Repository: richard-peng-xia/MMed-RAG
Branch: main
Commit: 45ceed33eef4
Files: 283
Total size: 64.5 MB
Directory structure:
gitextract_tizp684z/
├── .gitignore
├── LICENSE
├── README.md
├── data/
│ ├── test/
│ │ ├── report/
│ │ │ ├── harvard_test.json
│ │ │ ├── iuxray_test.json
│ │ │ ├── mimic_test.json
│ │ │ ├── pmc-oa_test.json
│ │ │ └── quilt-1m_test.json
│ │ └── vqa/
│ │ ├── harvard_test.jsonl
│ │ ├── iuxray_test.jsonl
│ │ ├── mimic_test.jsonl
│ │ ├── pmc-oa_test.jsonl
│ │ └── quilt-1m_test.jsonl
│ └── training/
│ ├── alignment/
│ │ ├── ophthalmology/
│ │ │ ├── harvard_report.json
│ │ │ └── harvard_vqa.json
│ │ ├── pathology/
│ │ │ └── pathology_vqa.json
│ │ └── radiology/
│ │ ├── radiology_report.json
│ │ └── radiology_vqa.json
│ └── retriever/
│ ├── ophthalmology/
│ │ ├── harvard_train_7000.json
│ │ └── harvard_val_1000.json
│ ├── pathology/
│ │ ├── pathology_train.json
│ │ └── pathology_val.json
│ └── radiology/
│ ├── radiology_train.json
│ └── radiology_val.json
├── requirements.txt
├── scripts/
│ ├── finetune_clip.sh
│ ├── retrieve_clip_VQA.sh
│ ├── retrieve_clip_report.sh
│ └── train_dpo_2stages.sh
└── train/
├── dpo/
│ ├── LICENSE
│ ├── cog.yaml
│ ├── dpo_trainer_2stages.py
│ ├── llava/
│ │ ├── __init__.py
│ │ ├── constants.py
│ │ ├── conversation.py
│ │ ├── conversation_new.py
│ │ ├── eval/
│ │ │ ├── eval_gpt_review.py
│ │ │ ├── eval_gpt_review_bench.py
│ │ │ ├── eval_gpt_review_visual.py
│ │ │ ├── eval_pope.py
│ │ │ ├── eval_science_qa.py
│ │ │ ├── eval_science_qa_gpt4.py
│ │ │ ├── eval_science_qa_gpt4_requery.py
│ │ │ ├── eval_textvqa.py
│ │ │ ├── generate_webpage_data_from_table.py
│ │ │ ├── m4c_evaluator.py
│ │ │ ├── model_qa.py
│ │ │ ├── model_vqa.py
│ │ │ ├── model_vqa_loader.py
│ │ │ ├── model_vqa_mmbench.py
│ │ │ ├── model_vqa_science.py
│ │ │ ├── qa_baseline_gpt35.py
│ │ │ ├── run_llava.py
│ │ │ ├── summarize_gpt_review.py
│ │ │ ├── table/
│ │ │ │ ├── answer/
│ │ │ │ │ ├── answer_alpaca-13b.jsonl
│ │ │ │ │ ├── answer_bard.jsonl
│ │ │ │ │ ├── answer_gpt35.jsonl
│ │ │ │ │ ├── answer_llama-13b.jsonl
│ │ │ │ │ └── answer_vicuna-13b.jsonl
│ │ │ │ ├── caps_boxes_coco2014_val_80.jsonl
│ │ │ │ ├── model.jsonl
│ │ │ │ ├── prompt.jsonl
│ │ │ │ ├── question.jsonl
│ │ │ │ ├── results/
│ │ │ │ │ ├── test_sqa_llava_13b_v0.json
│ │ │ │ │ └── test_sqa_llava_lcs_558k_sqa_12e_vicuna_v1_3_13b.json
│ │ │ │ ├── review/
│ │ │ │ │ ├── review_alpaca-13b_vicuna-13b.jsonl
│ │ │ │ │ ├── review_bard_vicuna-13b.jsonl
│ │ │ │ │ ├── review_gpt35_vicuna-13b.jsonl
│ │ │ │ │ └── review_llama-13b_vicuna-13b.jsonl
│ │ │ │ ├── reviewer.jsonl
│ │ │ │ └── rule.json
│ │ │ └── webpage/
│ │ │ └── styles.css
│ │ ├── mm_utils.py
│ │ ├── model/
│ │ │ ├── __init__.py
│ │ │ ├── apply_delta.py
│ │ │ ├── builder.py
│ │ │ ├── consolidate.py
│ │ │ ├── language_model/
│ │ │ │ ├── llava_llama.py
│ │ │ │ ├── llava_mistral.py
│ │ │ │ └── llava_mpt.py
│ │ │ ├── llava_arch.py
│ │ │ ├── make_delta.py
│ │ │ ├── multimodal_encoder/
│ │ │ │ ├── builder.py
│ │ │ │ └── clip_encoder.py
│ │ │ ├── multimodal_projector/
│ │ │ │ └── builder.py
│ │ │ └── utils.py
│ │ ├── serve/
│ │ │ ├── __init__.py
│ │ │ ├── cli.py
│ │ │ ├── controller.py
│ │ │ ├── gradio_web_server.py
│ │ │ ├── model_worker.py
│ │ │ ├── register_worker.py
│ │ │ ├── sglang_worker.py
│ │ │ └── test_message.py
│ │ ├── train/
│ │ │ ├── llama_flash_attn_monkey_patch.py
│ │ │ ├── llama_xformers_attn_monkey_patch.py
│ │ │ ├── llava_trainer.py
│ │ │ ├── train.py
│ │ │ ├── train_dpo.py
│ │ │ ├── train_dpo_inherent.py
│ │ │ ├── train_mem.py
│ │ │ └── train_xformers.py
│ │ └── utils.py
│ ├── llava_trainer_2stages.py
│ ├── povid_infer.py
│ ├── predict.py
│ ├── pyproject.toml
│ ├── scripts/
│ │ ├── convert_gqa_for_eval.py
│ │ ├── convert_mmbench_for_submission.py
│ │ ├── convert_mmvet_for_eval.py
│ │ ├── convert_seed_for_submission.py
│ │ ├── convert_sqa_to_llava.py
│ │ ├── convert_sqa_to_llava_base_prompt.py
│ │ ├── convert_vizwiz_for_submission.py
│ │ ├── convert_vqav2_for_submission.py
│ │ ├── extract_mm_projector.py
│ │ ├── finetune.sh
│ │ ├── finetune_full_schedule.sh
│ │ ├── finetune_lora.sh
│ │ ├── finetune_qlora.sh
│ │ ├── finetune_sqa.sh
│ │ ├── merge_lora_weights.py
│ │ ├── pretrain.sh
│ │ ├── pretrain_xformers.sh
│ │ ├── run_povid.sh
│ │ ├── sqa_eval_batch.sh
│ │ ├── sqa_eval_gather.sh
│ │ ├── upload_pypi.sh
│ │ ├── v1_5/
│ │ │ ├── eval/
│ │ │ │ ├── gqa.sh
│ │ │ │ ├── llavabench.sh
│ │ │ │ ├── mmbench.sh
│ │ │ │ ├── mmbench_cn.sh
│ │ │ │ ├── mme.sh
│ │ │ │ ├── mmvet.sh
│ │ │ │ ├── pope.sh
│ │ │ │ ├── qbench.sh
│ │ │ │ ├── qbench_zh.sh
│ │ │ │ ├── seed.sh
│ │ │ │ ├── sqa.sh
│ │ │ │ ├── textvqa.sh
│ │ │ │ ├── vizwiz.sh
│ │ │ │ └── vqav2.sh
│ │ │ ├── finetune.sh
│ │ │ ├── finetune_lora.sh
│ │ │ ├── finetune_task.sh
│ │ │ ├── finetune_task_lora.sh
│ │ │ └── pretrain.sh
│ │ ├── zero2.json
│ │ ├── zero3.json
│ │ └── zero3_offload.json
│ ├── tool/
│ │ ├── dpo_trainer.py
│ │ └── dpo_trainer_inherent.py
│ └── train_dpo_2stages.py
└── open_clip/
├── CITATION.cff
├── HISTORY.md
├── LICENSE
├── MANIFEST.in
├── setup.py
└── src/
├── open_clip/
│ ├── __init__.py
│ ├── big_vision.py
│ ├── coca_model.py
│ ├── constants.py
│ ├── factory.py
│ ├── hf_configs.py
│ ├── hf_model.py
│ ├── loss.py
│ ├── model.py
│ ├── model_configs/
│ │ ├── EVA01-g-14-plus.json
│ │ ├── EVA01-g-14.json
│ │ ├── EVA02-B-16.json
│ │ ├── EVA02-E-14-plus.json
│ │ ├── EVA02-E-14.json
│ │ ├── EVA02-L-14-336.json
│ │ ├── EVA02-L-14.json
│ │ ├── RN101-quickgelu.json
│ │ ├── RN101.json
│ │ ├── RN50-quickgelu.json
│ │ ├── RN50.json
│ │ ├── RN50x16.json
│ │ ├── RN50x4.json
│ │ ├── RN50x64.json
│ │ ├── ViT-B-16-SigLIP-256.json
│ │ ├── ViT-B-16-SigLIP-384.json
│ │ ├── ViT-B-16-SigLIP-512.json
│ │ ├── ViT-B-16-SigLIP-i18n-256.json
│ │ ├── ViT-B-16-SigLIP.json
│ │ ├── ViT-B-16-plus-240.json
│ │ ├── ViT-B-16-plus.json
│ │ ├── ViT-B-16-quickgelu.json
│ │ ├── ViT-B-16.json
│ │ ├── ViT-B-32-256.json
│ │ ├── ViT-B-32-plus-256.json
│ │ ├── ViT-B-32-quickgelu.json
│ │ ├── ViT-B-32.json
│ │ ├── ViT-H-14-378-quickgelu.json
│ │ ├── ViT-H-14-CLIPA-336.json
│ │ ├── ViT-H-14-CLIPA.json
│ │ ├── ViT-H-14-quickgelu.json
│ │ ├── ViT-H-14.json
│ │ ├── ViT-H-16.json
│ │ ├── ViT-L-14-280.json
│ │ ├── ViT-L-14-336.json
│ │ ├── ViT-L-14-CLIPA-336.json
│ │ ├── ViT-L-14-CLIPA.json
│ │ ├── ViT-L-14-quickgelu.json
│ │ ├── ViT-L-14.json
│ │ ├── ViT-L-16-320.json
│ │ ├── ViT-L-16-SigLIP-256.json
│ │ ├── ViT-L-16-SigLIP-384.json
│ │ ├── ViT-L-16.json
│ │ ├── ViT-M-16-alt.json
│ │ ├── ViT-M-16.json
│ │ ├── ViT-M-32-alt.json
│ │ ├── ViT-M-32.json
│ │ ├── ViT-S-16-alt.json
│ │ ├── ViT-S-16.json
│ │ ├── ViT-S-32-alt.json
│ │ ├── ViT-S-32.json
│ │ ├── ViT-SO400M-14-SigLIP-384.json
│ │ ├── ViT-SO400M-14-SigLIP.json
│ │ ├── ViT-bigG-14-CLIPA-336.json
│ │ ├── ViT-bigG-14-CLIPA.json
│ │ ├── ViT-bigG-14.json
│ │ ├── ViT-e-14.json
│ │ ├── ViT-g-14.json
│ │ ├── coca_ViT-B-32.json
│ │ ├── coca_ViT-L-14.json
│ │ ├── coca_base.json
│ │ ├── coca_roberta-ViT-B-32.json
│ │ ├── convnext_base.json
│ │ ├── convnext_base_w.json
│ │ ├── convnext_base_w_320.json
│ │ ├── convnext_large.json
│ │ ├── convnext_large_d.json
│ │ ├── convnext_large_d_320.json
│ │ ├── convnext_small.json
│ │ ├── convnext_tiny.json
│ │ ├── convnext_xlarge.json
│ │ ├── convnext_xxlarge.json
│ │ ├── convnext_xxlarge_320.json
│ │ ├── mt5-base-ViT-B-32.json
│ │ ├── mt5-xl-ViT-H-14.json
│ │ ├── nllb-clip-base-siglip.json
│ │ ├── nllb-clip-base.json
│ │ ├── nllb-clip-large-siglip.json
│ │ ├── nllb-clip-large.json
│ │ ├── roberta-ViT-B-32.json
│ │ ├── swin_base_patch4_window7_224.json
│ │ ├── vit_medium_patch16_gap_256.json
│ │ ├── vit_relpos_medium_patch16_cls_224.json
│ │ ├── xlm-roberta-base-ViT-B-32.json
│ │ └── xlm-roberta-large-ViT-H-14.json
│ ├── modified_resnet.py
│ ├── openai.py
│ ├── pos_embed.py
│ ├── pretrained.py
│ ├── push_to_hf_hub.py
│ ├── timm_model.py
│ ├── tokenizer.py
│ ├── transform.py
│ ├── transformer.py
│ ├── utils.py
│ ├── version.py
│ ├── zero_shot_classifier.py
│ └── zero_shot_metadata.py
├── retrieve_clip_VQA.py
├── retrieve_clip_report.py
└── training/
├── .gitignore
├── __init__.py
├── data.py
├── distributed.py
├── file_utils.py
├── logger.py
├── main.py
├── main_feature-work.py
├── main_retrieve_report.py
├── main_retrieve_report_harvard.py
├── params.py
├── precision.py
├── profiler.py
├── scheduler.py
├── train.py
└── zero_shot.py
================================================
FILE CONTENTS
================================================
================================================
FILE: .gitignore
================================================
backup
train/open_clip/.github
train/open_clip/.gitignore
train/open_clip/docs
train/open_clip/scripts
train/dpo/playground
# train/dpo/scripts
train/dpo/docs
train/dpo/wandb
train/open_clip/README.md
================================================
FILE: LICENSE
================================================
MIT License
Copyright (c) 2024 Peng "Richard" Xia
Permission is hereby granted, free of charge, to any person obtaining a copy
of this software and associated documentation files (the "Software"), to deal
in the Software without restriction, including without limitation the rights
to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
copies of the Software, and to permit persons to whom the Software is
furnished to do so, subject to the following conditions:
The above copyright notice and this permission notice shall be included in all
copies or substantial portions of the Software.
THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE
AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
SOFTWARE.
================================================
FILE: README.md
================================================
# MMed-RAG: Versatile Multimodal RAG System for Medical Vision Language Models
We introduce MMed-RAG, a powerful multimodal RAG system that boosts the factuality of Medical Vision-Language Models (Med-LVLMs) by up to 43.8%! 🩺 [[Paper](https://arxiv.org/abs/2410.13085)] [[X(Twitter)](https://x.com/HuaxiuYaoML/status/1847097594641584574)]
## 🚀 News
- [01/22/2025] MMed-RAG is accepted by ICLR 2025!
- [12/08/2024] The training scripts are released!
- [10/20/2024] The whole data is released in `data/`! Check it out!
- [10/18/2024] The manuscript can be found on [arXiv](https://arxiv.org/abs/2410.13085).
## 💡 Overview
MMed-RAG enhances alignment across medical domains like radiology, pathology, and ophthalmology with a domain-aware retrieval mechanism. And it tackles three key challenges in alignment of multimodal RAG:
1️⃣ Direct Copy Homework from Others❌ Think it by Self ✅
MMed-RAG helps Med-LVLMs avoid blindly copying external information by encouraging the model to rely on its own visual reasoning when solving complex problems.
2️⃣ Cannot Solve Problems by Self❌ Learn How to Copy ✅
When Med-LVLMs are unsure, MMed-RAG teaches the model to intelligently use retrieved knowledge, pulling in the right information at the right time, boosting accuracy, and reducing errors.
3️⃣ Copied Homework is Wrong❌ Avoid Interference from Incorrect Homework ✅
MMed-RAG prevents models from being misled by incorrect retrievals, reducing the risk of generating inaccurate medical diagnoses.
## 📦 Requirements
1. Clone this repository and navigate to MMed-RAG folder
```bash
git clone https://github.com/richard-peng-xia/MMed-RAG.git
cd MMed-RAG
```
2. Install Package: Create conda environment
```Shell
conda create -n MMed-RAG python=3.10 -y
conda activate MMed-RAG
cd MMed-RAG
pip install --upgrade pip # enable PEP 660 support
pip install -r requirements.txt
pip install trl
```
3. Download the required model checkpoints [LLaVA-Med-1.5](https://huggingface.co/microsoft/llava-med-v1.5-mistral-7b) from huggingface.
4. For all the medical datasets, you need firstly apply for the right of access and then download the dataset.
- [MIMIC-CXR](https://physionet.org/content/mimic-cxr-jpg/2.0.0/)
- [IU-Xray](https://drive.google.com/file/d/1c0BXEuDy8Cmm2jfN0YYGkQxFZd2ZIoLg/view) (Thanks to [R2GenGPT](https://github.com/wang-zhanyu/R2GenGPT) for sharing the file)
- [Harvard-FairVLMed](https://ophai.hms.harvard.edu/datasets/harvard-fairvlmed10k/)
- [PMC-OA](https://huggingface.co/datasets/axiong/pmc_oa)
- [Quilt-1M](https://github.com/wisdomikezogwo/quilt1m)
## 📖 Data Description
We provide a corresponding json or jsonl file for each dataset, including the image path, question, answer, and original report.
- Training: The data used to train the retriever and fine-tune the Med-LVLM are located in `data/training/retriever/MODALITY` and `data/training/alignment/MODALITY` respectively. Each folder contains data for VQA or report generation tasks.
- Test: All the test data for Med-LVLMs is placed under `data/test/TASK/MODALITY`.
`TASK`: report/vqa, `MODALITY`: radiology/pathology/ophthalmology.
## 🏋️ Train
### Retriver Fine-tuning
Use the following script, make sure to specify the data paths and the checkpoint saving location.
```
bash ./scripts/finetune_clip.sh
```
### Preference Fine-tuning
Use the script `train_dpo_2stages.sh` in `./script` or the following command, make sure to specify the necessary data paths and the checkpoint saving location.
```
deepspeed --include localhost:0,1,2,3 ./train/dpo/train_dpo_2stages.py \
--model_name_or_path /path/to/llava-med_model_checkpoint \
--deepspeed ./scripts/zero3.json \
--version v1 \
--lora_enable True --lora_r 128 --lora_alpha 256 --mm_projector_lr 2e-5 \
--data_path /path/to/data_json \
--image_folder /path/to/img_folder \
--vision_tower openai/clip-vit-large-patch14-336 \
--mm_projector_type mlp2x_gelu \
--mm_vision_select_layer -2 \
--mm_use_im_start_end False \
--mm_use_im_patch_token False \
--image_aspect_ratio pad \
--group_by_modality_length True \
--bf16 True \
--output_dir /path/to/output_checkpoint_saving_location \
--num_train_epochs 3 \
--per_device_train_batch_size 1\
--per_device_eval_batch_size 1 \
--gradient_accumulation_steps 1 \
--evaluation_strategy "no" \
--save_strategy "steps" \
--save_steps 200 \
--save_total_limit 1 \
--learning_rate 1e-7 \
--weight_decay 0. \
--warmup_ratio 0.03 \
--lr_scheduler_type "cosine" \
--logging_steps 1 \
--report_to wandb \
--tf32 True \
--model_max_length 1024 \
--gradient_checkpointing True \
--dataloader_num_workers 4 \
--lazy_preprocess True \
```
## 🥖 Retrieve
Use `retrieve_clip_report.sh` or `retrieve_clip_VQA.sh` to retrieve reports for report generation or VQA task. The script uses Harvard-FairVLMed dataset as an example. Make sure to specify the necessary data paths and the saving location.
## 📅 Schedule
- [x] Release the data (VQA and report generation tasks)
- [x] Release the training code
## 📚Citation
```bibtex
@article{xia2024mmedrag,
title={MMed-RAG: Versatile Multimodal RAG System for Medical Vision Language Models},
author={Xia, Peng and Zhu, Kangyu and Li, Haoran and Wang, Tianze and Shi, Weijia and Wang, Sheng and Zhang, Linjun and Zou, James and Yao, Huaxiu},
journal={arXiv preprint arXiv:2410.13085},
year={2024}
}
```
## 🙏Acknowledgement
We use code from [LLaVA-Med](https://github.com/microsoft/LLaVA-Med), [RULE](https://github.com/richard-peng-xia/RULE), [CARES](https://github.com/richard-peng-xia/CARES). We thank the authors for releasing their code.
================================================
FILE: data/test/report/harvard_test.json
================================================
[
{
"id": "data_08003",
"image_path": "slo_fundus_08003.jpg",
"filename": "data_08003.npz",
"report": "86-year-old white, non-hispanic female diagnosed with glaucoma.",
"age": 86.74,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "a 86 y.o. white, non-hispanic female was evaluated and diagnosed with glaucoma.",
"gpt4_summary": "86-year-old white, non-hispanic female diagnosed with glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08008",
"image_path": "slo_fundus_08008.jpg",
"filename": "data_08008.npz",
"report": "The clinical note prescribes erythromycin ophthalmic ointment for the patient's right eye. The patient is referred to ophthalmology. No mention of glaucoma. Other conditions include goiter, rheumatoid arthritis, etc.",
"age": 39.36,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "erythromycin (romycin) ophthalmic ointment place 0.5 inches into the right eye 4 (four) times a day. your orders normal orders this visit ambulatory referral to Institution ophthalmology humphrey visual field - ou - both eyes oct, optic nerve - ou - both eyes - condition list as of DATE_TIME goiter rheumatoid arthritis hemorrhoids fatigue vitamin d deficiency antinuclear factor positive fibromyalgia carpal tunnel syndrome thrombophlebitis disorder of thyroid premenopausal menorrhagia irregular menses contraception management results summary immunizations administered on date of encounter - DATE_TIME none",
"gpt4_summary": "The clinical note prescribes erythromycin ophthalmic ointment for the patient's right eye. The patient is referred to ophthalmology. No mention of glaucoma. Other conditions include goiter, rheumatoid arthritis, etc.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08009",
"image_path": "slo_fundus_08009.jpg",
"filename": "data_08009.npz",
"report": "Patient displays thin temporal os and hvf 24-2 shows corresponding inferior defects. Risk factors for glaucoma noted. Patient also has borderline diabetes, chronic anemia and a family history of macular degeneration.",
"age": 67.09,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "question ltg? risks include c/d asym iop is wnl, PERSON is -2, -3. oct rnfl shows thin superior ou, thin temporal os hvf 24-2 shows corresponding inferior defects os only, PERSON denies migraine required transfution ?chronic anemia from bleeding denies history of trauma, PERSON no apd patient reports pcp is following for borderline dmii hemoglobin a1c date value ref range status DATE_TIME 5.7 (h) 4.2 - 5.6 % final comment: hba1c levels 5.7-6.4% represent pre-diabetes, indicating impaired glucose control and an increased risk of developing diabetes. the diagnostic hba1c level for diabetes is 6.5% or greater. hba1c levels <4.2% may indicate a hemoglobinopathy or anemia, and an alternative method is recommended to monitor glucose control. mild combined forms of age related cataract ou continue to observe. fmhx of macular degeneration mother progressed to blindness before passed away mom was a smoker pvd od no holes/tears/breaks seen on exam. warned pt of rd symptoms. pt will rtc if they experience new/worsening symptoms or rd/rt symptoms. hyperopia ou w/ astigmatism od and presbyopia ou otc sheet given refer to glaucoma service in DATE_TIME by signing my name below, i, PERSON, acting as a scribe, attest that this documentation has been prepared under the direction and in the presence of PERSON, LOCATION DATE_TIME by signing my name below, i, PERSON, attest that this documentation has been prepared under my direction.",
"gpt4_summary": "Patient displays thin temporal os and hvf 24-2 shows corresponding inferior defects. Risk factors for glaucoma noted. Patient also has borderline diabetes, chronic anemia and a family history of macular degeneration.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08010",
"image_path": "slo_fundus_08010.jpg",
"filename": "data_08010.npz",
"report": "The 44-year-old patient has dry eye, pinguecula, and optic disc cupping. There are nonspecific defects in their visual field, and thinning in the superior and temporal sectors of the eye. No signs of glaucoma.",
"age": 44.72,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "44 y.o. with PERSON / dry eye > warm compresses, lid hygiene, artificial tears > flax seed / fish oil supplementation pinguecula ou > artificial tears optic disc cupping ou - no family hx - photos DATE_TIME - cct 531/527 - hvf DATE_TIME: reliable ou, nonspecific defects, essentially full ou DATE_TIME nonspecific defects ou DATE_TIME od borderline reliable, essentially full os borderline reliable inferior and paracentral defects - oct rnfl DATE_TIME: reliable ou, PERSON, os with superior thinning, borderline temporal thinning DATE_TIME od wnl os with superior thinning, borderline temporal thinning DATE_TIME 83/74 od wnl os with superior thinning, borderline temporal thinning PERSON today 10/10 > monitor for now, iop good off medication vitreous syneresis > no retinal breaks/ detachment fu DATE_TIME, mrx, dilate, hvf/ oct",
"gpt4_summary": "The 44-year-old patient has dry eye, pinguecula, and optic disc cupping. There are nonspecific defects in their visual field, and thinning in the superior and temporal sectors of the eye. No signs of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08013",
"image_path": "slo_fundus_08013.jpg",
"filename": "data_08013.npz",
"report": "Patient unhappy with post-surgery visual improvement due to severe glaucoma. Misunderstood pre-surgery conversations. Sought second opinion but decided to continue with current provider. Upcoming appointments scheduled for eyelid, cornea and low-vision care.",
"age": 64.7,
"gender": "male",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "patient is disappointed with result from surgery because vision 'didn't improve,' but i explained vision is limited by his severe glaucoma. i never promised/guaranteed outcomes to the patient, but he seems to have misunderstood our initial conversations before surgery. he also said he searched for second opinion in LOCATION, LOCATION, which i applauded. doctor there said he would 'adjust' something, but it's unclear to me what that means. ultimately i said it was ok to change providers (he had researched dr. PERSONon), but he said he'd give me 'one more try.' -scheduled to see dr. PERSON to establish eyelid care DATE_TIME. -follow-up with dr. PERSON for cornea care => will try to coordinate appointment as of DATE_TIME. -follow-up with dr. PERSON for mrx and low-vision care. -preservative-free artificial tears as needed. -rtc in DATE_TIME with iop check ou, hvf 10-2 od and hvf 24-2 os, sooner prn. i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow (PERSON, PERSON. i have reviewed the resident/fellow's notes and made any necessary changes. the information above was documented by PERSON as a scribe for PERSON on DATE_TIME. i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "Patient unhappy with post-surgery visual improvement due to severe glaucoma. Misunderstood pre-surgery conversations. Sought second opinion but decided to continue with current provider. Upcoming appointments scheduled for eyelid, cornea and low-vision care.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08016",
"image_path": "slo_fundus_08016.jpg",
"filename": "data_08016.npz",
"report": "The patient, a 65-year-old female, is a suspect for open-angle glaucoma, presenting no family history. She also has sulfa allergy, a history of trauma, and early cataracts. For now, no glaucoma treatment is planned.",
"age": 65.26,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "65 yo wf self referral, was seen prior by dr. PERSON poor. followed for DATE_TIME as glaucoma suspect. no fh, + sulfa allergy, no asthma, + trauma (as a child falls, soft ball injury (teeth), had car accident priror) 1. open angle glaucoma suspect ou - cct 539 ou - gonio ou: open ou, slightly narrow, but no iop change after dilation. - t max high teens per records. DATE_TIME mid teens without rx. - hvf full ou and oct with stable vertical thinning od and full os (stable per reviewing prior records) - long discussion was done about the nature of the disease, visual prognosis and management options at this stage, patient voiced understanding, all questions were answered. considering stable changes od on LOCATION/o multiple trauma prior, possible traumatic neuropathy od, will observe for now without glaucoma rx. r/b of observation vs prophylactic tx od discussed. rtc: DATE_TIME for iop, gonio, hvf ou, dialate ou, oct ou plan: observe without rx 2. early cataracts ou - nvs observe 3. myopia ou - ok with glasses, observe - dfe DATE_TIME - no holes or tears.",
"gpt4_summary": "The patient, a 65-year-old female, is a suspect for open-angle glaucoma, presenting no family history. She also has sulfa allergy, a history of trauma, and early cataracts. For now, no glaucoma treatment is planned.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08019",
"image_path": "slo_fundus_08019.jpg",
"filename": "data_08019.npz",
"report": "Patient is on brimonidine/alphagan for the left eye 2x/day & prednisolone for the right eye 1x/day. Advised not to rub operated eye for 4 weeks. Urged to contact the glaucoma department for any concerns.",
"age": 67.77,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "medication route frequency LOCATION (teal) the left eye DATE_TIME brimonidine/alphagan3 (purple) the left eye 2x/day prednisolone 1 (white or pink) the right eye 1x/day \u00f8 some medications that may be prescribed in lieu of this medication include: latanoprost, xalatan, travatan z, travaprost, LOCATION, LOCATION, LOCATION/tafluprost (preservative-free). 1 some medications that may be prescribed in lieu of this medication (topical steroid) include: prednisolone acetate, pred forte, durezol, LOCATION, LOCATION, LOCATION, loteprednol, fluorometholone. prednisolone should be shaken 20 times before placing it in the eye. 3 some medications that may be prescribed in lieu of this medication include: brimonidine, alphagan, PERSON avoid rubbing the operated eye for at least 4 full weeks. keep shield over operated eye at bedtime until instructed by medical doctor (usually DATE_TIME). no bending, straining or lifting anything heavier than 5 pounds until the doctor indicates it. always wait DATE_TIME (by the clock) in between eye drops. if you have eye pain, vision changes or other concerns, do not hesitate to contact the glaucoma department. for routine questions, please call PHONE_NUMBER (LOCATION, ask for glaucoma department) or PHONE_NUMBER (longwood). for emergencies, please call PHONE_NUMBER and ask for the glaucoma physician on-call. please bring this to your next visit.",
"gpt4_summary": "Patient is on brimonidine/alphagan for the left eye 2x/day & prednisolone for the right eye 1x/day. Advised not to rub operated eye for 4 weeks. Urged to contact the glaucoma department for any concerns.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08021",
"image_path": "slo_fundus_08021.jpg",
"filename": "data_08021.npz",
"report": "The patient, formerly of Pasquale, has primary open angle glaucoma and amblyopia in the left eye. Other issues include lattice in both eyes and a history of cataract extraction in both eyes.",
"age": 68.47,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "first seen by PERSON PERSON on DATE_TIME, former pasquale patient diagnosis:primary open angle glaucoma, amblyopia left eye (et) target iop: / , tmax: ( ) / ( ) 25 central corneal thickness: / 540 gonioscopy: refractive error: od . . / os . . optic nerve findings on initial visit right eye: mostly normal optic nerve findings on initial visit left eye: thin nfl visual fields on initial visit right eye: non-specific visual fields on initial visit left eye: superior arcuate medication history and intolerances: initially latanoprost glaucoma procedures right eye: glaucoma procedures left eye: other eye procedures right eye: cataract extraction other eye procedures left eye: cataract extraction other eye problems right eye: lattice other eye problems left eye: amblyopia, lattice family history: mother (94), steroids: no trauma: no asthma: no other medical history and problems: plan: \u00ff appears stable, check in DATE_TIME, vf and dilate",
"gpt4_summary": "The patient, formerly of Pasquale, has primary open angle glaucoma and amblyopia in the left eye. Other issues include lattice in both eyes and a history of cataract extraction in both eyes.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08022",
"image_path": "slo_fundus_08022.jpg",
"filename": "data_08022.npz",
"report": "Patient visited for a second opinion and was diagnosed with low tension glaucoma. Initial visit showed no thinning in the right eye, but focal superior thinning in left eye. Plans to start new medication regimen including timoptic, brimonidine and continuing latanoprost. ",
"age": 55.12,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "first seen by dr. LOCATION on DATE_TIME self referred for second opinion diagnosis: low tension glaucoma dx DATE_TIME target iop: DATE_TIME, tmax: 19 ( ) / 20 ( ) set target empirically, limited data goal may not need to be this low, especially od central corneal thickness: 533.533.533 / 531.531.531 gonioscopy: refractive error: od . . / os . . optic nerve findings on initial visit right eye: no definite thinning, although trend on oct rnfl optic nerve findings on initial visit left eye: focal superior thinning. visual fields on initial visit right eye: full visual fields on initial visit left eye: inferior nasal step, LOCATION medication history and intolerances: PERSON bid ou - pt reports too expensive latanoprost qhs ou glaucoma procedures right eye : none glaucoma procedures left eye : none other eye procedures: none family history: no glaucoma niece with retinal PERSON steroids: no trauma/eye surgery: none plan: stop combigan start timoptic start brimonidine continue latanoprost DATE_TIME dfe if iop still above goal next visit consider slt laser vs adding dorzolamide.",
"gpt4_summary": "Patient visited for a second opinion and was diagnosed with low tension glaucoma. Initial visit showed no thinning in the right eye, but focal superior thinning in left eye. Plans to start new medication regimen including timoptic, brimonidine and continuing latanoprost. ",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08024",
"image_path": "slo_fundus_08024.jpg",
"filename": "data_08024.npz",
"report": "61 y.o. white, non-hispanic male with no diagnosis of glaucoma. Requested to mail clinical note to specific person and location.",
"age": 61.93,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "a 61 y.o. white, non-hispanic male with no diagnosis of glaucoma. can you please mail a copy of my note to PERSON PERSON at LOCATION? thank you!",
"gpt4_summary": "61 y.o. white, non-hispanic male with no diagnosis of glaucoma. Requested to mail clinical note to specific person and location.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08032",
"image_path": "slo_fundus_08032.jpg",
"filename": "data_08032.npz",
"report": "61 y.o. male suspect for glaucoma due to family history, ocular hypertension, and high intraocular pressure (IOP: 29/32). His father possibly had glaucoma. Patient also has incipient senile cataract, myopia, astigmatism, and presbyopia.",
"age": 61.65,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "61 y.o. male presents for a comprehensive eye exam. he was last seen by me DATE_TIME. PERSON: ocular hypertension, father with possible glaucoma pmhx: htn since the last visit he notes in the morning he sees a white ring around his peripheral vision that then clears up. difficulty driving with current rx for distance. assessment/plan: # glaucoma suspect/ohtn - glaucoma suspect based on family history and iop , c/d - iop - 29/32 on intake, rechecked to be 23/26 - tmax - unknown, mid to high 20s per patient - cct - 590/596 thick ou - c/d - 0.35. 0.35 - gonio - open to cbb ou - family history - possibly father later in life - last hvf performed - not done yet - last oct rnfl performed - DATE_TIME - full ou, increased c/d but healthy rnfl - fundus photos obtained - DATE_TIME - dilated optic nerve exam performed ou DATE_TIME - discussed potential for progressive irreversible vision loss due to glaucomatous optic neuropathy due to high eye pressure and results of ohts trial - return in DATE_TIME with hvf 24-2, oct rnfl, gonio before dilation # incipient senile cataract # myopia with astigmatism and presbyopia - va 20/20 ou with current rx - can continue current rx - small change in rx without improvement in visual acuity rtc DATE_TIME or sooner prn with hvf 24-2, oct rnfl - no dilation PERSON, md",
"gpt4_summary": "61 y.o. male suspect for glaucoma due to family history, ocular hypertension, and high intraocular pressure (IOP: 29/32). His father possibly had glaucoma. Patient also has incipient senile cataract, myopia, astigmatism, and presbyopia.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08035",
"image_path": "slo_fundus_08035.jpg",
"filename": "data_08035.npz",
"report": "76yo patient has depression, htn, breast cancer, visually significant cataract, pseudophakia os, and glaucoma (recently diagnosed, on latanoprost). No family history of glaucoma. IOP is OK but concern about hvf defect. Also has allergic conjunctivitis, and conjunctival pigment.",
"age": 76.43,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "single",
"note": "76 yo patient pmh depression, htn, breast ca last seen by me DATE_TIME \u00ff cataract od - starting to become visually significant; pt denies any difficulty with vision and no significant anisometropia - observe for now \u00ff pseudophakia os s/p ce/iol DATE_TIME at LOCATION - doing well \u00ff glaucoma - recently diagnosed at LOCATION and started on latanoprost ou qhs - iop DATE_TIME, 13 previously 15 - no family history of glaucoma - gonio DATE_TIME open to ss 4 quadrants ou - cct 500, 495- iop likely higher than measured - rnfl DATE_TIME:poor signal strength; ? inferior thinning ou - rnfl DATE_TIME: poor quality nerve and gca - hvf 9/19: os scattered deficits; od dense PERSON tracking turned off but per technicians poor ability to cooperate and so may be unreliable - hvf DATE_TIME: od 3/12 fl, dense superonasal quandrantic defect that persists from last scan os: scattered inferior and nasal defects; no evidence of homonymous defect - disc photos DATE_TIME: c/d 0.6 ou, full LOCATION, os with some superior thinning; normal vessels and visible macula - dfe DATE_TIME wnl - plan: refer to glaucoma. i asked her to bring PERSON records to visit (i do not have these or know the history of her glaucoma diagnosis.) iop is ok, but i am concerned about the persistent hvf defect. of note, the defect is dense and quadrantic, respecting horizontal and vertical meridiens, but does not appear to be homonymous \u00ff allergic conjunctivitis - continue to use zatditor prn \u00ff conjunctival pigment - observe in the setting of xalatan \u00ff patient to followup with urgent changes as needed; otherwise see glaucoma next available and will return in 6 m with me _____________________ \u00ff PERSON, md, mph comprehensive ophthalmology LOCATION",
"gpt4_summary": "76yo patient has depression, htn, breast cancer, visually significant cataract, pseudophakia os, and glaucoma (recently diagnosed, on latanoprost). No family history of glaucoma. IOP is OK but concern about hvf defect. Also has allergic conjunctivitis, and conjunctival pigment.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08040",
"image_path": "slo_fundus_08040.jpg",
"filename": "data_08040.npz",
"report": "The note discusses a 62-year-old female with blepharitis, who experiences significant improvement with ocusoft wipes. She wears multifocal contact lenses and is being referred to optometry. She is suspected of having glaucoma due to an increased c/d ratio, despite normal intraocular pressure. Other factors like family history or steroid medication use are ruled out. Eye scans reveal borderline changes and thinning superiorly. Future visits are scheduled for ongoing evaluation.",
"age": 62.49,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "62f # blepharitis -uses ocusoft wipes with great improvement >PERSON >warm compresses >omega 3 fa >at prn # refractive: wears multifocal contact lenses, and progressives. very happy >refer to optometry for cl eval # glaucoma suspect: increased c/d ratio -normal iop, no history of steroid medications, no fhx -pachy 530/530 -disc photos DATE_TIME -oct DATE_TIME: od borderline changes; os thinning superiorly -hvf DATE_TIME: full ou >follow DATE_TIME for now rtc DATE_TIME: coe, hvf, oct disc",
"gpt4_summary": "The note discusses a 62-year-old female with blepharitis, who experiences significant improvement with ocusoft wipes. She wears multifocal contact lenses and is being referred to optometry. She is suspected of having glaucoma due to an increased c/d ratio, despite normal intraocular pressure. Other factors like family history or steroid medication use are ruled out. Eye scans reveal borderline changes and thinning superiorly. Future visits are scheduled for ongoing evaluation.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08047",
"image_path": "slo_fundus_08047.jpg",
"filename": "data_08047.npz",
"report": "Patient shows signs of glaucoma. Hx of amblyopia in left eye. No HIV retinopathy. Marked cupping OD>OS. Intraocular pressure highly elevated. RNFL thinning OD. Normal HVF.",
"age": 40.65,
"gender": "male",
"race": "white",
"ethnicity": "hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "imp: hx ambly os (20/70 bcva) no hiv retinopathy cupping od>os, vertical notch od. iop highly elevated DATE_TIME. open on gonio. rnfl with progressive thinning od, hvf normal -cct 560s ou previously -administered cosopt and brimonidine x1 ou in clinic small ch nevus od refr error plan: cosopt bid ou referral to glaucoma rx=m yrly cos",
"gpt4_summary": "Patient shows signs of glaucoma. Hx of amblyopia in left eye. No HIV retinopathy. Marked cupping OD>OS. Intraocular pressure highly elevated. RNFL thinning OD. Normal HVF.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08049",
"image_path": "slo_fundus_08049.jpg",
"filename": "data_08049.npz",
"report": "This clinical note does not provide any medical information or mention the presence of glaucoma. It primarily guides on account activation in a newly developed portal.",
"age": 62.46,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "user account. important information about your account: \u0007 if you already have a account, please sign in with your existing username and your account will automatically be activated in our new portal - \u0007",
"gpt4_summary": "This clinical note does not provide any medical information or mention the presence of glaucoma. It primarily guides on account activation in a newly developed portal.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08050",
"image_path": "slo_fundus_08050.jpg",
"filename": "data_08050.npz",
"report": "Patient has presbyopia and glaucoma. Undergoing treatment to control intraocular pressure (IOP). Recent procedures include phaco/xen gel stent. Plans to possibly continue with phaco/xen procedure on next visit.",
"age": 71.81,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "and presbyopia, both eyes -stable. 6. social/systemic issues: patient referred to clinic after ed visit on DATE_TIME. i requested the patient to transfer any relevant medical records concerning her glaucoma. attending's plan: -goal intraocular pressure less than or equal to 17 mmhg, right eye. -goal intraocular pressure less than or equal to 14 mmhg, left eye. -iop at goal od and at goal os on DATE_TIME on timolol bid od, LOCATION bid od and s/p phaco/xen gel stent os. -decrease LOCATION to qhs ou (from bid od) to control iop od and keep iop in the very low teens os. -continue ocudose bid od. -instructions written/typed/printed out for patient (see table/details under patient instructions). -emphasized adherence to medication regimen. -preservative-free artificial tears as needed. -retinal detachment precautions were reviewed with the patient. -long discussion with patient on DATE_TIME: given iop above goal os and numerous allergies os, we proceeded with phaco/open xen gel stent os with 3-piece in the bag (li) due to pxf on DATE_TIME. -rtc in DATE_TIME with iop check ou, bat od, optical biometry ou, and oct rnfl/gcc ou, sooner prn. strongly consider phaco/xen od next visit. the information above was documented by PERSON as a scribe for PERSON on DATE_TIME.",
"gpt4_summary": "Patient has presbyopia and glaucoma. Undergoing treatment to control intraocular pressure (IOP). Recent procedures include phaco/xen gel stent. Plans to possibly continue with phaco/xen procedure on next visit.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08054",
"image_path": "slo_fundus_08054.jpg",
"filename": "data_08054.npz",
"report": "Patient, 68, with GERD, hypertension, intraocular pressure is 16/16, previously was 18/17, 26/23, max of 26/23. Patient has ocular hypertension. C/D ratio is 0.5/0.5, open on gonioscopy. No mention of glaucoma.",
"age": 68.25,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "68 y.o. with gerd, hypertension ocular hypertension ou - tcurrent: 16/16 - t previous: 26/23, 18/17 - tmax: 26/23 - tgoal: - c/d ratio: 0.5/0.5 - gonioscopy: open ou - central corneal thickness: DATE_TIME: DATE_TIME wnl ou DATE_TIME wnl ou DATE_TIME wnl ou DATE_TIME 84/87 wnl both eyes DATE_TIME 86/88 wnl ou - hvf: DATE_TIME full ou DATE_TIME full ou DATE_TIME full ou DATE_TIME full both eyes DATE_TIME od full os high fp, nonspecific defects - family history: +mother - race: aa - optic nerve photos >? iop better/stable on latanoprost ou, continue immature cataract ou - not visually significant > observe dry eye - has occ burning, itching. better on artificial tears refractive error - no change fu DATE_TIME mrx, dilate, hvf/ oct",
"gpt4_summary": "Patient, 68, with GERD, hypertension, intraocular pressure is 16/16, previously was 18/17, 26/23, max of 26/23. Patient has ocular hypertension. C/D ratio is 0.5/0.5, open on gonioscopy. No mention of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08055",
"image_path": "slo_fundus_08055.jpg",
"filename": "data_08055.npz",
"report": "The patient has glaucoma and is considering different types of surgery. Due to the severe irritation caused by current medication, they proceeded with phaco/trab mmc os. Follow-up planned for IOP check.",
"age": 75.92,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "only. -continue e-mycin qhs os as needed for comfort. -instructions written/typed/printed out for patient (see table/details under patient instructions) previously.*** -emphasized adherence to medication regimen. -preservative-free artificial tears as needed. -long discussion with patient on DATE_TIME: patient has given a lot of thought to the different types of glaucoma surgery (and whether to have it or not given stable hvf), and given the need of 5 agents to control iop os (some of which are causing severe irritation), she proceeded with phaco/trab mmc os on DATE_TIME. -rtc in DATE_TIME with iop check ou, hvf ou, dilation ou, and oct rnfl/gcc os only by experienced technician (please try to obtain 9/10 signal strength), sooner prn. DATE_TIME iop disc the information above was documented by PERSON as a scribe for PERSON on DATE_TIME.",
"gpt4_summary": "The patient has glaucoma and is considering different types of surgery. Due to the severe irritation caused by current medication, they proceeded with phaco/trab mmc os. Follow-up planned for IOP check.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08056",
"image_path": "slo_fundus_08056.jpg",
"filename": "data_08056.npz",
"report": "Visual field test is to be performed on the left eye with lid taping, following monocular precautions. No mention of glaucoma.",
"age": 69.99,
"gender": "female",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "married or partnered",
"note": "DATE_TIME, visual field to be performed on the left eye only with lid taping 2. monocular precautions 1. follow up in neuro-op in DATE_TIME, visual field to be performed on the left eye only with lid taping 2. monocular precautions this note was prepared.",
"gpt4_summary": "Visual field test is to be performed on the left eye with lid taping, following monocular precautions. No mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08057",
"image_path": "slo_fundus_08057.jpg",
"filename": "data_08057.npz",
"report": "Patient has suspected myelinated nerve fiber layer od, near circumferential on exam. Experiencing enlarging blind spot; advised to bring records to next appointment. No mention of glaucoma.",
"age": 61.89,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "unknown",
"note": "subjective PERSON given assessment and plan \u00ff suspected myelinated nerve fiber layer od: - near circumferential on exam - per patient, has had enlarging blind spot on recent visual fields over DATE_TIME, has been followed at spindell eye, optometrist following concerned by visual field changes and told to come here - cos referral, would recommend obtaining baseline photos and visual field; in the interim, instructed patient to bring all records to this appointment PERSON, PERSON DATE_TIME DATE_TIME \u00ff PERSON, PERSONE DATE_TIME",
"gpt4_summary": "Patient has suspected myelinated nerve fiber layer od, near circumferential on exam. Experiencing enlarging blind spot; advised to bring records to next appointment. No mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08058",
"image_path": "slo_fundus_08058.jpg",
"filename": "data_08058.npz",
"report": "The patient has glaucoma and is taking multiple medications: Timolol/Brimonidine 1x/night in both eyes, Dorzolamide 3x/day in right eye, Netarsudil 1x/night in right eye, and artificial tears as needed in both eyes.",
"age": 72.18,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "medication route frequency PERSON (teal)6 both eyes 1x/night timolol/brimonidine** (dark blue) the right eye 3x/day dorzolamide (orange)& both eyes 3x/day netarsudil (white)4 the right eye 1x/night preservative free artificial tears both eyes 6-8x/day as needed \u00f8 some medications that may be prescribed in lieu of this medication include: latanoprost, xalatan, travatan z, travaprost, LOCATION, LOCATION, LOCATION/tafluprost (preservative-free). 6 this medication is also known as vyzulta. ** this medication is also known as combigan, and it represents a combination of timolol and brimonidine. & some medications that may be prescribed in lieu of this medication include: dorzolamide, trusopt, PERSON, brinzolamide. 4 this medication is also known as rhopressa. always wait DATE_TIME (by the clock) in between eye drops. please bring this to your next visit. for routine questions, please call PHONE_NUMBER (LOCATION, ask for glaucoma department) or PHONE_NUMBER (longwood). for emergencies, please call PHONE_NUMBER and ask for the glaucoma physician on-call.",
"gpt4_summary": "The patient has glaucoma and is taking multiple medications: Timolol/Brimonidine 1x/night in both eyes, Dorzolamide 3x/day in right eye, Netarsudil 1x/night in right eye, and artificial tears as needed in both eyes.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08066",
"image_path": "slo_fundus_08066.jpg",
"filename": "data_08066.npz",
"report": "69 y.o. male has dry eyes, blepharitis, ocular hypertension, cataracts (not visually significant), refractive error. No glaucoma detected. Monitoring for now.",
"age": 69.8,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "69 y.o. male # dry eyes / blepharitis >at qid prn >warm compresses >omega-3 fatty acids >consider doxy # ocular hypertension ou -neg fhx -cct 594 / 606 -oct rnfl DATE_TIME: normal ou -hvf DATE_TIME: full ou >discussed monitoring vs starting drops. monitor for now. # cataract ou -not visually significant >monitor # refractive error >mrx given DATE_TIME f/u DATE_TIME: gonio, iop",
"gpt4_summary": "69 y.o. male has dry eyes, blepharitis, ocular hypertension, cataracts (not visually significant), refractive error. No glaucoma detected. Monitoring for now.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08068",
"image_path": "slo_fundus_08068.jpg",
"filename": "data_08068.npz",
"report": "Patient is a glaucoma suspect, with myopia being a risk factor. Intraocular pressure is within normal range, with possible mild corneal arcus. New prescription for myopia with astigmatism and presbyopia given. The patient also has cataracts and borderline high cholesterol.",
"age": 52.86,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "glaucoma suspect risks are myopia. iop is wnl, t corr is +3 ou. c/d - 0.4. 0.5 no fmhx. oct onh nfl wnl ou, gcl PERSON unreliable possible artifact LOCATION. hvf 24-2 watch inferior od wnl os DATE_TIME. myopia with astigmatism and presbyopia new rx given. warned of rd symptoms. cataracts ou multifocal PERSON with PERSON. states he does not wear his scl anywhere. observe. mild corneal arcus h/o borderline high cholesterol. observe. f/u in DATE_TIME for LOCATION, oct.",
"gpt4_summary": "Patient is a glaucoma suspect, with myopia being a risk factor. Intraocular pressure is within normal range, with possible mild corneal arcus. New prescription for myopia with astigmatism and presbyopia given. The patient also has cataracts and borderline high cholesterol.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08073",
"image_path": "slo_fundus_08073.jpg",
"filename": "data_08073.npz",
"report": "Patient seeking second opinion for eye issues. Goals include reducing intraocular pressure in both eyes. Glaucoma suspected due to elevated intraocular pressure. Current treatment includes Zioptan and PERSON medication and Xen Gel Stent procedure.",
"age": 56.51,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "here for second opinion on DATE_TIME (referred by a patient of mine, ms. PERSON). attending's plan: -goal intraocular pressure less than or equal to 17 mmhg, right eye. -goal intraocular pressure less than or equal to 12 mmhg, left eye. -iop at goal od and above goal os on DATE_TIME on zioptan qhs os, PERSON, and s/p xen gel stent os. -continue PERSON -continue zioptan qhs os. -restart rhopressa qhs os. -hold PERSON> sample given on DATE_TIME. -instructions written/typed/printed out for patient (see table/details under patient instructions). -emphasized adherence to medication regimen. -preservative-free artificial tears as needed. -long discussion with patient on DATE_TIME: given elevated iop os on close to mtmtx and desire to minimize eye drop burden, we proceeded with open xen gel stent os on DATE_TIME. -rtc in DATE_TIME with iop check and disc photos ou, sooner prn. in future, we could try ocudose bid os, or pf cosopt bid os only (maybe branded PERSON as well). we may want to consider bgi os if iop still above goal and especially if progression demonstrated given numerous intolerances to medication. the information above was documented by PERSON as a scribe for PERSON on DATE_TIME.",
"gpt4_summary": "Patient seeking second opinion for eye issues. Goals include reducing intraocular pressure in both eyes. Glaucoma suspected due to elevated intraocular pressure. Current treatment includes Zioptan and PERSON medication and Xen Gel Stent procedure.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08075",
"image_path": "slo_fundus_08075.jpg",
"filename": "data_08075.npz",
"report": "Patient suspected of glaucoma due to cupping, has myopic astigmatism, Type 1 diabetes without retinopathy, and scheduled for silent sinus syndrome surgery.",
"age": 50.97,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "cos clinic note assessment/plan: 1. glaucoma suspect due to cupping -full hvf at baseline, full rnfl -iop acceptable for now 2. myopic astigmatism -rx prn 3. diabetes type 1 without retinopathy ou -bg control -annual dfe 4. silent sinus syndrome -scheduled for surgery (ent) at DATE_TIME -pre-operative hertels exophthalmetry shows between 2-3mm enophthalmos of the right eye -follow-up after recovery from surgery to monitor degree of enophthalmos -report sent to dr. PERSON in DATE_TIME after sinus surgery for undilated exam",
"gpt4_summary": "Patient suspected of glaucoma due to cupping, has myopic astigmatism, Type 1 diabetes without retinopathy, and scheduled for silent sinus syndrome surgery.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08077",
"image_path": "slo_fundus_08077.jpg",
"filename": "data_08077.npz",
"report": "Patient referred for suspected open angle glaucoma with low risk in both eyes. Risk factors include family history of glaucoma (mother) and long-term steroid use. No history of eye trauma or other eye procedures. Undergone IOP tonometry with pressure 23 both eyes. No glaucoma medication issues or allergies. Advised follow up.",
"age": 38.1,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "PERSON is a DATE_TIME DATE_TIME patient referred by outside optometrist, first seen by dr. LOCATION on DATE_TIME # ohtn # open angle glaucoma suspect low risk od, low risk os risk factors: positive family history of glaucoma or blindness (mother with pigmentary dispersion), positive history of longterm steroids (steroid cream for eczema since ~2020), negative history of eye trauma (k abrasions only) central corneal thickness: 442 / 446 (DATE_TIME)gonioscopy: open ou tmax: ( ) / ( ) target iop: / refractive error wrx: od . . / os . . glaucoma procedures/lasers: none other eye procedures/lasers: none glaucoma medication issues: negative history of asthma negative history of bradycardia negative sulfa allergy negative history of renal disfuntion or kidney stones testing: baseline DATE_TIME (DATE_TIME) oct rnfl: (DATE_TIME) hvf 24-2 ou: #social: pt is pediatrician at Institution (nicu) #hx k abraision x 2 - once was a scratch and the other was a chemical in the eye/ lab related - unclear laterality # systemic: anxiety, svt s/p ablation plan DATE_TIME: iop tonometry tonometry (3:04 pm) right left pressure 23 23 discussed the natural history of glaucoma, diagnosis of glaucoma supspect, and the importance of follow up. paracentral defects both eyes left eye is superior and right eye is inferior which does correspond to thinning on optical coherence tomography. last dilated exam: DATE_TIME rnfl:DATE_TIME last visual field: DATE_TIME baseline disc photos: return to glaucoma clinic DATE_TIME with dilated fundus exam, disc photos, PERSON, and please check wrx (just read the glasses that she is wearing please)",
"gpt4_summary": "Patient referred for suspected open angle glaucoma with low risk in both eyes. Risk factors include family history of glaucoma (mother) and long-term steroid use. No history of eye trauma or other eye procedures. Undergone IOP tonometry with pressure 23 both eyes. No glaucoma medication issues or allergies. Advised follow up.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08078",
"image_path": "slo_fundus_08078.jpg",
"filename": "data_08078.npz",
"report": "Patient has PVD in right eye, mild cataract in both eyes, and normal, non-glaucomatous cupping in both eyes. Yearly follow-up planned.",
"age": 64.48,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "imp: pvd od mild cataract ou cupping ou--appears to be physiologic; +fh gl testing stable, wnl shallow ac; angles open by gonio refr error plan: yrly sooner prn j NRP, pgy4 i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow. i have reviewed the resident/fellow's notes and made any necessary changes.",
"gpt4_summary": "Patient has PVD in right eye, mild cataract in both eyes, and normal, non-glaucomatous cupping in both eyes. Yearly follow-up planned.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08083",
"image_path": "slo_fundus_08083.jpg",
"filename": "data_08083.npz",
"report": "Madeline recently underwent glaucoma surgery in left eye. Her conditions include open angle glaucoma in both eyes, pseudophakia, astigmatism, myopia, presbyopia, and asthma. Showing improvement, but further treatment may be considered.",
"age": 65.06,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "madeline a PERSON is a DATE_TIME. female ref for second opinion following recent glaucoma surgery in the left eye with PERSON eye history, from notes: s/p iridocyclitis os s/p bleb revision w mmc, 5fu and PERSON well s/p slt os (temp 1/2) pseudophakia ou s/p argon laser NRP os hyperopia astigmatism presbyopia posterior vitreous detachment od h/o suprachoroidal hemorrhage os myopia astigmatism presbyopia 1. open angle glaucoma ou s/p trab DATE_TIME, s/p bleb revision os DATE_TIME dr. PERSON at ocb, performed due to hypotony-->iop has improved hvf 9/17 early nasal changes od since DATE_TIME (prior to that ess full); os sa stable since DATE_TIME with inferior thinning ou + asthma travatan qhs od 2. pseudophakia ou plan: discussed current presentation and prognosis in detail, all questions answered. travatan qhs od dc pred PERSON is borderline in od and trending up in os. goal is likely mid teens od, low teens os. repeat iop check after stopping prednisolone--if not at goal, consider additional agent ou (vs slt od/gtt os) rtc sooner prn",
"gpt4_summary": "Madeline recently underwent glaucoma surgery in left eye. Her conditions include open angle glaucoma in both eyes, pseudophakia, astigmatism, myopia, presbyopia, and asthma. Showing improvement, but further treatment may be considered.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08096",
"image_path": "slo_fundus_08096.jpg",
"filename": "data_08096.npz",
"report": "The patient is currently taking econazole, sulfacetamide sodium-sulfur, valacyclovir, and acetaminophen-codeine for various conditions. They underwent Humphrey Visual Field and OCT optic nerve tests. Conditions include varicose veins and hypertension. No mention of glaucoma.",
"age": 63.79,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "total) by mouth DATE_TIME. econazole nitrate 1 % cream (taking) apply topically DATE_TIME. sulfacetamide sodium-sulfur (prascion) 10-5 % (w/w) clsr (taking) apply topically 2 (two) times a day. valacyclovir (valtrex) 1000 mg tablet (taking) take 2 tablets (2,000 mg total) by mouth 2 (two) times a day. x DATE_TIME only, as needed for cold sores PERSON DATE_TIME as needed acetaminophen-codeine (tylenol-codeine #PHONE_NUMBER mg per tablet take 1-2 tablets by mouth every 4 (DATE_TIME as needed. partial fill ok your orders normal orders this visit humphrey visual field - ou - both eyes oct, optic nerve - ou - both eyes - cirrus; optic disc; rnfl; 6mm length condition list as of DATE_TIME varicose veins of lower extremities with other complications hypertension results summary immunizations administered on date of encounter - DATE_TIME none",
"gpt4_summary": "The patient is currently taking econazole, sulfacetamide sodium-sulfur, valacyclovir, and acetaminophen-codeine for various conditions. They underwent Humphrey Visual Field and OCT optic nerve tests. Conditions include varicose veins and hypertension. No mention of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08097",
"image_path": "slo_fundus_08097.jpg",
"filename": "data_08097.npz",
"report": "63-year-old patient with history of hypertension, hyperlipidemia, diabetes, GERD, back pain, and thyroidectomy for Graves' disease. No glaucoma mentioned but patient has controlled hyperglycemia, mild cataracts, occasional floaters, and dry eyes.\n",
"age": 63.85,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "63 yo disabled medical assistant with history of htn, hyperlipidemia, diabetes, gerd, low back pain, hypothyroidism s/p thyroidectomy for graves' disease has 15 and 10 PERSON in revere. mva DATE_TIME, recovering from l knee injury \u00ff 1. dm diagnosed DATE_TIME -history of gestational dm -hba1c 8.1% DATE_TIME >> 7.5% DATE_TIME >> 7.1% DATE_TIME no evidence of diabetic retinopathy on dilated fundus examination DATE_TIME. patient was advised to maintain tight control of blood sugar and blood pressure. \u00ff 2. history of graves disease, s/p rai -slight orbital fat prominence/hooding ou, but no other orbital signs \u00ff 3. cataracts ou-mild - not yet visually significant, denies glare, but is using sunglasses more frequently in the sun, anxious about driving at DATE_TIME but not due to vision >> updated mrx given DATE_TIME at request, no change in rx \u00ff 4. pvd ou -sees occasional floaters \u00ff 5. incr'd c/d od> os: intact rims tmax 22/21. cct 590/600 (thick). no fhx hvf DATE_TIME: full ou oct DATE_TIME: wnl ou oct DATE_TIME: wnl ou baseline oct DATE_TIME: wnl ou >> iop and onh stable, continue to follow \u00ff 6. dry eyes/mgd ou: clean lids in am or in shower prn >> artificial tears prn, also has patanol prn (uses rarely), prefers brand name patanol, finds this works best PERSON i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow. i have reviewed the resident/fellow's notes and made any necessary changes.",
"gpt4_summary": "63-year-old patient with history of hypertension, hyperlipidemia, diabetes, GERD, back pain, and thyroidectomy for Graves' disease. No glaucoma mentioned but patient has controlled hyperglycemia, mild cataracts, occasional floaters, and dry eyes.\n",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08101",
"image_path": "slo_fundus_08101.jpg",
"filename": "data_08101.npz",
"report": "Patient has history of poor compliance with glaucoma treatments. Diagnosis: mild glaucoma. Medications: latanoprost, timolol. Glaucoma procedures performed on both eyes. Assessment: thin cornea, progression of vision field loss, irreversible nature of glaucoma discussed. Plan: restart latanoprost and timolol.",
"age": 73.22,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "first seen by Person on DATE_TIME. previously seen dr. PERSON. he is here for transfer of care due to distance to main campus. he has a history of poor compliance and stopping eye drops for DATE_TIME. diagnosis: mild PERSON target iop: / , tmax: ( ) / ( ) central corneal thickness: 489 / 490 gonioscopy: cbb, 2+ pigment refractive error: od . . / os . . optic nerve/rnfl findings on baseline visit right eye (DATE_TIME): borderline superior/inferior thinning optic nerve/rnfl findings on baseline visit left eye (DATE_TIME): possible borderline superior thinning visual fields on baseline visit right eye (DATE_TIME): superior nasal step visual fields on baseline visit left eye (DATE_TIME): full medication history at first visit: latanoprost, timolol medication intolerances: rhopressa (cost) glaucoma procedures right eye: glaucoma procedures left eye: other eye procedures right eye: other eye procedures left eye: other eye problems right eye: other eye problems left eye: family history: mother steroids: trauma: asthma: other medical history and problems: assessment: 1. mild poag od>os -thin cct -poor compliance with hvf progression od; new baseline set DATE_TIME -discussed irreversible nature of glaucoma and strong recommendation to restart drops 2. ns cataracts ou -pt feels like vision or glasses have gotten weaker; refract next visit 3. posterior vitreous detachment od -last dfe DATE_TIME, was stable -rd precautions plan: -restart timolol 2/2, latanoprost 1/1 -pt undergoing cardiac surgery DATE_TIME; so we will defer next iop check until patient is medically stable return in DATE_TIME for mrx, iop, dilate",
"gpt4_summary": "Patient has history of poor compliance with glaucoma treatments. Diagnosis: mild glaucoma. Medications: latanoprost, timolol. Glaucoma procedures performed on both eyes. Assessment: thin cornea, progression of vision field loss, irreversible nature of glaucoma discussed. Plan: restart latanoprost and timolol.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08106",
"image_path": "slo_fundus_08106.jpg",
"filename": "data_08106.npz",
"report": "Patient with breast cancer history follows up for idiopathic intracranial hypertension (iih). Despite weight gain, visual status remains stable. Concerns over increased intracranial pressure discussed. No glaucoma mentioned.",
"age": 35.59,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "formulation: this patient with a history of breast cancer (s/p mastectomy with negative nodes, chemo/radiation) follows-up for iih. she seems to be doing very well from a visual standpoint, but she has gained considerable weight. my exam showed excellent afferent and efferent visual function (note that the field in one eye had to be repeated because of poor performance, which then improved). funduscopy reveals moderate frisen grade i edema ou. \u00ff i am very concerned about the weight gain, despite the essentially unchanged visual status, because it can trigger higher intracranial pressures. we had a significant talk about the risk and how we might manage that risk. she decided to again try to manage her diet, which is complicated by her 'craving' of sugar. i redressed the benefit of seeing a nutritionist, and she stated that she would call someone with whom she had previously worked. i encouraged regular weighings. we discussed use of diamox but we deferred, pending her weight in DATE_TIME. i also discussed a social worker-therapist, but she did not want to pursue this. she committed to a 10 pound weight loss by next visit. impression: 1. idiopathic intracranial hypertension, mild and stable without medical intervention 2. history of breast cancer \u00ff recommendations: 1. more attention to weight management 2. follow-up neuro-ophthalmic examination in DATE_TIME. consider initiating acetazolamide in the future",
"gpt4_summary": "Patient with breast cancer history follows up for idiopathic intracranial hypertension (iih). Despite weight gain, visual status remains stable. Concerns over increased intracranial pressure discussed. No glaucoma mentioned.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08107",
"image_path": "slo_fundus_08107.jpg",
"filename": "data_08107.npz",
"report": "Patient has diabetes type 2, history of stroke with left homonymous hemianopsia. RNFL showing superior thinning indicators of glaucoma. Cataracts present but not visually significant. Glaucoma consultation advised.",
"age": 58.5,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "-dm type 2 - no retinopathy -history of a stroke DATE_TIME, left homonymous hemianopsia -?poag: >>rnfl significant superior thinning ou, temporal and inferior thinning os >>hvf: right homonymous hemianopsia consistent with stroke, ?inferior nasal step os may benefit from glaucoma referral -refractive error/presbyopia -cataracts ou - not visually significant dilated exam cursory given pt. requesting to leave because of transportation issue. LOCATION, pgy4 this patient was unable to stay to see the attending and was only seen by the resident above. i have reviewed the resident's notes --suggest consultation with glaucoma service",
"gpt4_summary": "Patient has diabetes type 2, history of stroke with left homonymous hemianopsia. RNFL showing superior thinning indicators of glaucoma. Cataracts present but not visually significant. Glaucoma consultation advised.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08109",
"image_path": "slo_fundus_08109.jpg",
"filename": "data_08109.npz",
"report": "80 y.o. patient with cataracts and a history of glaucoma. Cataract surgery was delayed due to COVID-19. The patient hasn't been using prescribed medication, resulting in high intraocular pressure (IOP).",
"age": 80.22,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "80 y.o. previously followed by dr. PERSON at bidmc last seen in DATE_TIME, was told she had cataracts ou last visit DATE_TIME. was supposed to have cataract surgery but postponed due to covid pandemic hx glaucoma - iop 14 ou - cct 580/568 - rnfl DATE_TIME od thin sup os wnl DATE_TIME 64/92 od this sup, borderline temporal, inferiorly; PERSON DATE_TIME high fn ou, od superior and inferior arcuate defect, os rim artifact - pt ran out of DATE_TIME and has not been using. iop to high DATE_TIME. > restart latanoprost nightly ou > consider istent ou combined cataract bilateral - visually significant and affecting activities of DATE_TIME living - dilates well, [no ] flomax, [no ] pxf, [no ] guttae, [no] blood thinners - discussed cataract surgery, patient elected to proceed with cataract surgery with iol left eye. right eye to follow. with istent > risks, benefits, and alternatives to surgery were discussed with the patient, including but not limited to the potential risk of infection, bleeding, loss of vision, loss of eye, need for further surgery or laser, retinal detachment, change in glasses and reading glasses, macular edema, increased eye pressure and glaucoma. no guarantees given. all patient questions were answered.? > discussed available iols including presbyopia and astigmatism correcting lenses including all out-of-pocket expenses. > pt opts for monofocal iol, aim distance ?> anesthesia: peribulbar block > other concerns:",
"gpt4_summary": "80 y.o. patient with cataracts and a history of glaucoma. Cataract surgery was delayed due to COVID-19. The patient hasn't been using prescribed medication, resulting in high intraocular pressure (IOP).",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08112",
"image_path": "slo_fundus_08112.jpg",
"filename": "data_08112.npz",
"report": "51 y.o. female, suspected glaucoma due to increased cdr. Negative family history, normal OCT, mild nonspecific changes OD in HVF. Monitoring refractive error.",
"age": 51.73,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "assessment and plan 51 y.o. female with h/o left-sided bell's palsy # glaucoma suspect due to mildly incr cdr -neg fhx -pachy: 520/524 -oct DATE_TIME: normal ou -hvf DATE_TIME: reduced reliability ou, mild nonspec changes od, full os >monitor # refractive error >mrx given (svl reading) rtc DATE_TIME: coe, hvf, oct",
"gpt4_summary": "51 y.o. female, suspected glaucoma due to increased cdr. Negative family history, normal OCT, mild nonspecific changes OD in HVF. Monitoring refractive error.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08119",
"image_path": "slo_fundus_08119.jpg",
"filename": "data_08119.npz",
"report": "Patient is a glaucoma suspect but has normal visual fields in both eyes. Intraocular pressure and testing show stable results. No treatment initiated, planned for monitoring.",
"age": 73.99,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "first seen by dr. PERSON on DATE_TIME diagnosis: glaucoma suspect target iop: DATE_TIME, tmax: 14 (DATE_TIME) / 15.9 (DATE_TIME) central corneal thickness: 567.567.568 / 579.579.579 corneal hysteresis: 11.7 / 11.4* gonioscopy: refractive error: od +1.25. -0.25. 102 / os +1.25. -0.25. 087 optic nerve findings on initial visit right eye: optic nerve findings on initial visit left eye: visual fields on initial visit right eye: normal visual fields on initial visit left eye: normal medication history and intolerances: none glaucoma procedures right eye: none glaucoma procedures left eye: none other eye procedures right eye: none other eye procedures left eye: none other eye problems right eye: none other eye problems left eye: none family history: sister, no vision loss steroids: no trauma: no asthma: no other medical history and problems: none plan: # glaucoma suspect due to cup to disc ratio, both eyes - intraocular pressure acceptable both eyes, testing stable both eyes and findings reassuring on examination - continue to monitor without initiating treatment - return to clinic DATE_TIME for intraocular pressure check, humphrey visual field, optical coherence tomography and dilate # cataract, both eyes - mild, not visually significant, monitor i, PERSON, am acting as scribe for PERSONmd, PERSON for patient PERSON on DATE_TIME.",
"gpt4_summary": "Patient is a glaucoma suspect but has normal visual fields in both eyes. Intraocular pressure and testing show stable results. No treatment initiated, planned for monitoring.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08120",
"image_path": "slo_fundus_08120.jpg",
"filename": "data_08120.npz",
"report": "The 67 y.o. male patient has a history of glaucoma (POAG), with an increased c:d ratio and controlled IOP. He also shows ocular scars and has a history of ocular migraines and scleral lens wear.",
"age": 67.95,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "67 y.o. m 1. s/p phaco/pciol os (aim intermediate) doing well happy with vision mild pco, recheck next time (pt not bothered yet) 2. poag(s), based on inc c:d ratio ou fhx negative tmax mid teens per pt report PERSON full ou cct thin ou oct abnl thinning, stable ou dp stable iop controlled ou (goal low teens ou) and hvf full observe closely 3. cr scars ou in macula, stable, f/u dr young, - amd vs pattern dystrophy 4. ocular migraine, no ha followed, 1st episode DATE_TIME no recent sx 5. h/o scl wear monovision, od distance, os near no longer wearing PERSON has svd for DATE_TIME driving only, and prefers no correction for near DATE_TIME. s/p phaco/pciol od (aim distance) DATE_TIME, mild pco, recheck next time (pt not bothered yet) f/u 6 PERSON check",
"gpt4_summary": "The 67 y.o. male patient has a history of glaucoma (POAG), with an increased c:d ratio and controlled IOP. He also shows ocular scars and has a history of ocular migraines and scleral lens wear.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08127",
"image_path": "slo_fundus_08127.jpg",
"filename": "data_08127.npz",
"report": "27 y.o. white, non-hispanic female. No diagnosis of glaucoma. Exam as needed. Assisted by Huy Nguyen, PGY3.",
"age": 27.87,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "unknown",
"note": "a 27 y.o. white, non-hispanic female with no diagnosis of glaucoma. examination prn (this note was prepared with assistance from huy nguyen, pgy3)",
"gpt4_summary": "27 y.o. white, non-hispanic female. No diagnosis of glaucoma. Exam as needed. Assisted by Huy Nguyen, PGY3.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08132",
"image_path": "slo_fundus_08132.jpg",
"filename": "data_08132.npz",
"report": "The patient is taking timolol 0.5% ophthalmic gel, dropped in each eye daily. They are also taking trazodone orally. The patient has been referred for visual field and optic nerve examinations. No mention of glaucoma. Other health conditions include chronic renal impairment, hyperkalemia, hyperlipidemia, gout, hypothyroidism, GERD, and hypertension.\n",
"age": 86.55,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "married or partnered",
"note": "timolol (timoptic-xe) 0.5 % ophthalmic gel-forming (taking) place 1 drop into each eye daily. trazodone hcl (trazodone oral) (taking) take by mouth. your orders normal orders this visit ambulatory referral to Institution ophthalmology humphrey visual field - ou - both eyes oct, optic nerve - ou - both eyes - cirrus; rnfl condition list as of DATE_TIME chronic renal impairment hyperkalemia hyperlipidemia gout hypothyroidism gastroesophageal reflux disease hypertensive disorder results summary immunizations administered on date of encounter - DATE_TIME none patient gateway activation information your account is ready to use. activate your account using following steps: 1. visit URL. 2. click 'enroll now' and create your user account. important information about your account: ? if you already have a account, please sign in with your username and password. ? you must log into your account within DATE_TIME or activation code will expire. ? trouble logging in? use support link found on the top right side of the login page. ? need help? support team makes every effort to respond to phone or email messages within DATE_TIME. to reach the support team, email EMAIL_ADDRESSPHONE_NUMBER. calls or messages are answered DATE_TIME, DATE_TIME, est - and will make every effort to contact you within DATE_TIME.",
"gpt4_summary": "The patient is taking timolol 0.5% ophthalmic gel, dropped in each eye daily. They are also taking trazodone orally. The patient has been referred for visual field and optic nerve examinations. No mention of glaucoma. Other health conditions include chronic renal impairment, hyperkalemia, hyperlipidemia, gout, hypothyroidism, GERD, and hypertension.\n",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08135",
"image_path": "slo_fundus_08135.jpg",
"filename": "data_08135.npz",
"report": "The patient has been advised to use warm compresses and stop eye rubbing. Potential referral for ABMD. Needs to return to the Glaucoma Clinic for further tests.",
"age": 59.32,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "prescribing encouraged warm compresses bid, pf ats qid stop eye rubbing last dilated exam: DATE_TIME last oct rnfl: DATE_TIME last visual field: DATE_TIME baseline disc photos: DATE_TIME consider referral to cornea for abmd if symptomatically not improved return to glaucoma clinic in DATE_TIME with NRP, humphrey visual field 24-2, and optical coherence tomography retinal nerve fiber layer.",
"gpt4_summary": "The patient has been advised to use warm compresses and stop eye rubbing. Potential referral for ABMD. Needs to return to the Glaucoma Clinic for further tests.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08136",
"image_path": "slo_fundus_08136.jpg",
"filename": "data_08136.npz",
"report": "Patient is a suspect of narrow angle glaucoma due to hereditary reasons. She previously suffered sudden vision loss and had been diagnosed with Posner-Schlossman syndrome. She's also had episodes of bright light vision, diagnosed as ocular migraines. She had laser peripheral iridotomy (LPI), which reduced the symptoms. The patient's intraocular pressure is currently acceptable and her visual field is stable, but she has mild posterior capsular opacification in right eye. Follow-up planned in 6 months.",
"age": 70.87,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "1) narrow angle glaucoma suspect ou - fh: mother - angle closure; no steroids or trauma - complex recent eye history: pt always told she had open angles DATE_TIME: sudden vision loss od and flu-like symptoms, headache; iop 51; initially diagnosed with posner-schlossman; LOCATION with LOCATION, LOCATION, also prednisolone, now off all drops DATE_TIME: had several episodes of seeing bright light ou lasting or DATE_TIME, seen by neuro-ophth, diagnosed with ocular migraines and also told she had narrow angles had lpis ou in DATE_TIME, no episodes since - gonio DATE_TIME narrow, with very small pis (barely visible and not patent os) - oct full, hvf full - repeat iridotomy od and os DATE_TIME - ce ou in LOCATION DATE_TIME) pciol ou - PERSON plan: doing well intraocular pressure acceptable rnfl oct and visual field stable mild posterior capsular opacification right eye rtc 6 mths dilate, disc photos",
"gpt4_summary": "Patient is a suspect of narrow angle glaucoma due to hereditary reasons. She previously suffered sudden vision loss and had been diagnosed with Posner-Schlossman syndrome. She's also had episodes of bright light vision, diagnosed as ocular migraines. She had laser peripheral iridotomy (LPI), which reduced the symptoms. The patient's intraocular pressure is currently acceptable and her visual field is stable, but she has mild posterior capsular opacification in right eye. Follow-up planned in 6 months.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08140",
"image_path": "slo_fundus_08140.jpg",
"filename": "data_08140.npz",
"report": "The patient has glaucoma. The intraocular pressure (IOP) is above target in both eyes, an additional medication (Rhopressa) was recommended due to new disc hemorrhage in right eye and increasing IOP, but the patient refused. Retinal detachment precautions reviewed.",
"age": 61.86,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "glaucoma as well as other theories (as of DATE_TIME). attending's plan: -goal intraocular pressure less than or equal to 14 mmhg, right eye. -goal intraocular pressure less than or equal to 14 mmhg, left eye. -iop above goal ou on DATE_TIME on PERSON. -continue vyzulta qhs ou. -long discussion with patient on DATE_TIME: i strongly recommended starting rhopressa qhs ou in addition to vyzulta qhs ou given iop above goal ou (set by dr. PERSON) and new disc hemorrhage od noted on DATE_TIME with iop of 12 mmhg. she vehemently refused despite risk of permanent irreversible vision loss explained to the patient. -retinal detachment precautions were reviewed with the patient. -preservative-free artificial tears as needed. -rtc in DATE_TIME with iop check, hvf, dilation, and disc photos ou, sooner prn. if persistently above goal, recurring disc hemorrhages or progression, i will revisit treatment or urge patient to explore a second opinion. i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow (PERSON, md). i have reviewed the resident/fellow's notes and made any necessary changes. i spent DATE_TIME with the patient, more than half of which was spent on counseling and coordination of care for this patient's glaucoma and other ocular co-morbidities.",
"gpt4_summary": "The patient has glaucoma. The intraocular pressure (IOP) is above target in both eyes, an additional medication (Rhopressa) was recommended due to new disc hemorrhage in right eye and increasing IOP, but the patient refused. Retinal detachment precautions reviewed.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08141",
"image_path": "slo_fundus_08141.jpg",
"filename": "data_08141.npz",
"report": "The patient is taking timolol/brimonidine, also known as Combigan, for both eyes 2x/day and the right eye 3x/day. This indicates the presence of glaucoma.",
"age": 70.29,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "results summary immunizations administered on date of encounter - DATE_TIME none instructions from this visit: medication route frequency timolol/brimonidine** (dark blue) both eyes 2x/day PERSON (orange)& the right eye 3x/day ** this medication is also known as combigan, and it represents a combination of timolol and brimonidine. & some medications that may be prescribed in lieu of this medication include: dorzolamide, trusopt, PERSON, brinzolamide. always wait DATE_TIME (by the clock) in between eye drops. please bring this to your next visit. for routine questions, please call PHONE_NUMBER (LOCATION) or PHONE_NUMBER (LOCATION). for emergencies, please call PHONE_NUMBER and ask for the glaucoma physician on-call.",
"gpt4_summary": "The patient is taking timolol/brimonidine, also known as Combigan, for both eyes 2x/day and the right eye 3x/day. This indicates the presence of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08142",
"image_path": "slo_fundus_08142.jpg",
"filename": "data_08142.npz",
"report": "Patient has ocular hypertension, with heavy pigment and Pseudoexfoliation Syndrome (PXE). No definite damage noted. Higher PXE and intraocular pressure indicate need for monitoring. Diagnosed as glaucoma suspect.",
"age": 71.53,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "# ocular hypertension pxe , os>od +fhx, brother and mother PERSON ou ttarget: / , tmax: 26/24 (for a long time per patient, never treated) cct: / gonioscopy: open ou, heavy pigment os rnfl PERSON vf normal ou plan: no definite damage at this time pxe os and iop running higher needs close monitoring check pachy next visit , dilate, rtc 4 mths diagnosis of glaucoma/glaucoma suspect discussed with patient - review of natural history and management options discussed. importance of lifelong follow up and adherence to treatments discussed in order to lower risk of permanent vision loss/blindness from glaucoma. all questions answered.",
"gpt4_summary": "Patient has ocular hypertension, with heavy pigment and Pseudoexfoliation Syndrome (PXE). No definite damage noted. Higher PXE and intraocular pressure indicate need for monitoring. Diagnosed as glaucoma suspect.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08147",
"image_path": "slo_fundus_08147.jpg",
"filename": "data_08147.npz",
"report": "Patient screening shows no signs of fever, cough, breath shortness, sore throat, muscle aches, nasal congestion, or loss of smell/taste. No concerning symptoms or comorbidities. No mention of glaucoma.\n",
"age": 68.74,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "PERSON pre-visit symptom screening date: DATE_TIME symptoms fever: no cough: no mild shortness of breath: no sore throat: no muscle aches: no nasal congestion: no loss of smell/taste: no atypical symptom concerning for PERSON: no concerning symptoms or comorbidities: no additional symptom comments:not answered date of symptom onset: not answered pre-visit screening in DATE_TIME, has the patient had a positive or pending DATE_TIME test outside of Institution? no in DATE_TIME, has the patient spent DATE_TIME within 6 feet of anyone currently infected with DATE_TIME? no",
"gpt4_summary": "Patient screening shows no signs of fever, cough, breath shortness, sore throat, muscle aches, nasal congestion, or loss of smell/taste. No concerning symptoms or comorbidities. No mention of glaucoma.\n",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08148",
"image_path": "slo_fundus_08148.jpg",
"filename": "data_08148.npz",
"report": "Patient has posterior vitreous detachment (PVD) in right eye (OD), nuclear sclerotic (NS) cataract in both eyes (OU), and suspected glaucoma more in left eye (OS) than right.",
"age": 59.78,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "cos clinic note assessment/plan: 1. pvd od -repeat dfe without any rts or rds -rd return precautions reviewed 2. ns cataract ou -monitor 3. glaucoma suspect os>od -gonio open, PERSON, cct 516/515 -hvf and oct with slight defects os only -would monitor off of iop meds to establish trend rtc in DATE_TIME for iop, hvf ou",
"gpt4_summary": "Patient has posterior vitreous detachment (PVD) in right eye (OD), nuclear sclerotic (NS) cataract in both eyes (OU), and suspected glaucoma more in left eye (OS) than right.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08155",
"image_path": "slo_fundus_08155.jpg",
"filename": "data_08155.npz",
"report": "Patient is a 62-year-old endoscopy nurse with various conditions including hypertension, hyperlipidemia, diabetes, sleep apnea, coronary artery disease, etc. Has ocular hypertension with thick corneas and a high risk of glaucoma due to family history.",
"age": 62.05,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "62 yo endoscopy rn at bmc with history of htn, hyperlipidemia, dm, sleep apnea, cad s/p 4-vessel cabg 5/21/1/4 (sternal wound debridement 6/27, flap DATE_TIME), hashimoto's thyroiditis, cervical dysplasia s/p leep DATE_TIME, gerd, anemia, psoriasis,pseudogout \u00ff 1. s/p phaco/pciol ou (DATE_TIME od and DATE_TIME os) - tr pco os> od, but remains asymptomatic >> requested mrx DATE_TIME \u00ff 2. diabetes x DATE_TIME -hba1c 8.1% DATE_TIME >> 6.8% DATE_TIME >> 6.8% DATE_TIME >> 8.9% DATE_TIME >> 6.9% DATE_TIME >> 8.3% DATE_TIME (ordered for low bcva): wnl ou no evidence of diabetic retinopathy on examination DATE_TIME. patient was advised to maintain tight control of blood sugar and blood pressure. \u00ff 3. ocular hypertension tmax 20/18. cct DATE_TIME: 582/569 (thick/ave) +strong family history of glaucoma (brother (s/p mx rd) and father (now deceased)) gonio DATE_TIME: cbb 360' ou hvf DATE_TIME: full ou hvf DATE_TIME: od full with non-specific defects, os full hvf DATE_TIME: full ou hvf DATE_TIME: od full. os borderline superior rim losses. (dif from DATE_TIME) hvf DATE_TIME: od borderline superior rim losses. os full DATE_TIME: wnl ou oct DATE_TIME: od sup thinning, worse than prior. os wnl DATE_TIME: PERSON, stable. PERSON, poor signal DATE_TIME. oct DATE_TIME: od borderline superior thinning, stable. os wnl DATE_TIME: od borderline superior thinning. os wnl >> DATE_TIME: iop stable. DATE_TIME worse but it historically fluctuates and no clear hvf correlate. will follow \u00ff 4. mild erm os - asymptomatic \u00ff 5. pvd od >> rd precautions \u00ff 6. peripapillary choroidal pigmentation",
"gpt4_summary": "Patient is a 62-year-old endoscopy nurse with various conditions including hypertension, hyperlipidemia, diabetes, sleep apnea, coronary artery disease, etc. Has ocular hypertension with thick corneas and a high risk of glaucoma due to family history.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08158",
"image_path": "slo_fundus_08158.jpg",
"filename": "data_08158.npz",
"report": "72 y.o. female with history of fibromyalgia and breast cancer. She displays low suspicion of glaucoma, no significant cataracts and dry eye syndrome. Also has refractive error.",
"age": 72.34,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "72 y.o. female with h/o fibromyalgia, possible chronic fatigue syndrome, breast ca diagnosed in DATE_TIME s/p surgery/radiation previously followed by PERSON suspect based on cup:disc asymmetry os>od (low suspicion) noted to have pigment in anterior chamber post-dilation by dr. PERSON in past; no k spindle visible on exam fam hx: denies tmax: 18/19 cct: PERSON gonio DATE_TIME: ou open to ptm hvf DATE_TIME: od full, os few inferior rim defects DATE_TIME: PERSON, os few inferior defects likely full rnfl DATE_TIME: ou wnl DATE_TIME: ou wnl and stable disc photos: DATE_TIME last dilated: DATE_TIME >> observe off eyedrops - narrow angles ou not occludable on gonioscopy DATE_TIME >> monitor. signs & symptoms of acute angle closure glaucoma discussed - combined senile cataract ou not visually significant and not affecting activities of DATE_TIME living at this time >> observe - meibomian gland dysfunction/dry eye syndrome ou dry ocular surface DATE_TIME, reports intermittent irritation >> treatment with warm compresses, fish/flaxseed oil, artificial tears discussed - refractive error >> a prescription for new glasses was given to the patient last visit. f/up DATE_TIME with mrx, bat, hvf, rnfl oct, gonio, then dilation discussed longer wait times due to need testing, gonio by md, then dilation. pt stated understanding; ok with this as long as appts scheduled on DATE_TIME",
"gpt4_summary": "72 y.o. female with history of fibromyalgia and breast cancer. She displays low suspicion of glaucoma, no significant cataracts and dry eye syndrome. Also has refractive error.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08159",
"image_path": "slo_fundus_08159.jpg",
"filename": "data_08159.npz",
"report": "The patient has visual field defects potentially from a right-sided homonymous defect and Wet AMD. Brain MRI ordered to rule out left occipital ischemic event. No mention of glaucoma.",
"age": 72.02,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "left side that could represent an acute/subacute occipital ischemic event. i believe that the patient could have noticed the visual field defect only in the left eye because the vision in her right eye is more severely impaired. her visual fields are hard to interpret given the defects caused by the amd, but there is a nasal visual field defect in the left eye and a corresponding temporal field defect in the right eye that could potentially represent a right-sided homonymous visual field defect. given that finding, i ordered a brain mri to rule out an occipital ischemic event. i will decide on further management depending on the results from the imaging. impression: 1. wet amd - treated with eylea 2. ?new right homonymous visual field defect - rule out ischemic event in the left occipital lobe 3. pseudophakia ou 4. pco os plan: 1. mri brain 2. follow up depending on the results of #1 PERSON, md",
"gpt4_summary": "The patient has visual field defects potentially from a right-sided homonymous defect and Wet AMD. Brain MRI ordered to rule out left occipital ischemic event. No mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08160",
"image_path": "slo_fundus_08160.jpg",
"filename": "data_08160.npz",
"report": "The patient has stable chronic conditions, including glaucoma \u2013 evident from good Intraocular Pressure (IOP) control. Currently, on a drug regimen (Cosopt) which should continue, especially as moderate risk of progression without care. Moderate activity such as marathon training can resume.",
"age": 41.31,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "given that iop pressures were at goal, we decided to observe on current regimen. we discussed slt and a handout was provided in case patient wants to come off cosopt. i recommended that he still continue the current medication regimen given that his tmax was 55 mmhg os, and he is about to resume marathon training. -long discussion with patient on DATE_TIME: given stable chronic illnesses with good iop control, we will continue monitoring the patient on the prescription drug regimen described above. importance of follow-up explained to patient given moderate risk of progression without care. we reviewed hvf/oct together, and they were stable! -rtc in DATE_TIME for iop check, dilation, and disc photos ou, sooner prn. strict return precautions, especially if marathon training resumes. the information above was documented by PERSON as a scribe for PERSON on DATE_TIME. i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "The patient has stable chronic conditions, including glaucoma \u2013 evident from good Intraocular Pressure (IOP) control. Currently, on a drug regimen (Cosopt) which should continue, especially as moderate risk of progression without care. Moderate activity such as marathon training can resume.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08162",
"image_path": "slo_fundus_08162.jpg",
"filename": "data_08162.npz",
"report": "74 yo woman with oculopharyngeal muscular dystrophy has cataracts, is considering surgery. Increased c/d. No family history of glaucoma. Vision within normal limits on assessments. Experiencing diplopia.",
"age": 74.81,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "74 yo woman with history of oculopharyngeal muscular dystrophy x DATE_TIME new patient DATE_TIME, prior care at tufts c/o needs glasses to see, must use glasses for distance and tv 1. cataract ou DATE_TIME: -starting to become symptomatic os>od with DATE_TIME driving -would like to observe for now, considering surgery for DATE_TIME after she returns from DATE_TIME in LOCATION 2. incr'd c/d ou tmax 15 ou. cct DATE_TIME (ave). no fhx glaucoma. hvf DATE_TIME: full ou (os fixation losses) 1st hvf DATE_TIME: od reliable, wnl. os rare rim losses DATE_TIME: wnl ou oct DATE_TIME: wnl ou oct DATE_TIME: PERSON ou >> will follow 3. s/PERSON 3 (PERSON), most recently 8/17 -very happy with results 4. PERSON (she is uncertain if binocular) -noted only at distance during DATE_TIME, noted over DATE_TIME >> orthophoric in primary gaze, only -1 limitation os in elevation abduction, and adduction, but denies diplopia >> neuro-op consultation for diplopia in setting of omd. in meantime will update glasses prescription for optimal acuity",
"gpt4_summary": "74 yo woman with oculopharyngeal muscular dystrophy has cataracts, is considering surgery. Increased c/d. No family history of glaucoma. Vision within normal limits on assessments. Experiencing diplopia.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08165",
"image_path": "slo_fundus_08165.jpg",
"filename": "data_08165.npz",
"report": "The patient has uveitis-glaucoma-hyphema syndrome and angle recession in left eye. Their right eye has a mild, not visually significant cataract. No thinning in retinal nerve fiber layer for either eye. They were intolerant to brimonidine glaucoma medication. No family history of eye diseases.",
"age": 50.26,
"gender": "male",
"race": "white",
"ethnicity": "hispanic",
"language": "english",
"maritalstatus": "single",
"note": "first seen by dr. PERSON on DATE_TIME glaucoma medication intolerances: brimonidine (follicular conjunctivitis) target iop: DATE_TIME, tmax: 24 / 46 central corneal thickness: 547 / 540 gonioscopy: od: d35f 2+; os: PERSON 4+, s/p nasal goniotomy retinal nerve fiber layer, right eye: no thinning retinal nerve fiber layer, left eye: no thinning visual fields, right eye: full visual fields, left eye: full family history: none steroids: none trauma: fell and hit head as a teenager asthma/copd: none other medical history and problems: generally healthy assessment/plan: 50 y.o. male # uveitis-glaucoma-hyphema (ugh) syndrome and angle recession, left eye - s/p iol exchange/kahook os (DATE_TIME, ma60ac +19.0 d in LOCATION, truncated superior haptic of prior sa60at remains in capsular bag) - initially presented to Institution ed DATE_TIME with iop 46 that improved with drops; inferior iol optic/haptic was out of capsular bag and subluxed inferiorly/anteriorly - iop acceptable ou, vf and oct stable - continue dorzolamide/timolol bid os - return in DATE_TIME for iop check, dilate, disc photos # cataract, right eye - mild, not visually significant, monitor PERSON, md",
"gpt4_summary": "The patient has uveitis-glaucoma-hyphema syndrome and angle recession in left eye. Their right eye has a mild, not visually significant cataract. No thinning in retinal nerve fiber layer for either eye. They were intolerant to brimonidine glaucoma medication. No family history of eye diseases.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08166",
"image_path": "slo_fundus_08166.jpg",
"filename": "data_08166.npz",
"report": "The patient has primary open angle glaucoma, moderate stage in right eye and mild stage in left eye. They also suffer from essential hypertension, class 1 obesity, uterine leiomyoma.",
"age": 64.06,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "DATE_TIMEtitution comp oph mc tech PERSON main campus DATE_TIME DATE_TIME PERSONtitution comprehensive oph main campus PHONE_NUMBER orders placed this visit humphrey visual field - ou - both eyes oct, optic nerve - ou - both eyes - cirrus; optic disc; rnfl condition list as of DATE_TIME uterine leiomyoma essential hypertension class 1 obesity healthcare maintenance mva restrained driver abnormal magnetic resonance imaging of cervical spine primary open angle glaucoma of right eye, moderate stage primary open angle glaucoma of left eye, mild stage results summary immunizations administered on date of encounter",
"gpt4_summary": "The patient has primary open angle glaucoma, moderate stage in right eye and mild stage in left eye. They also suffer from essential hypertension, class 1 obesity, uterine leiomyoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08168",
"image_path": "slo_fundus_08168.jpg",
"filename": "data_08168.npz",
"report": "Patient experienced transient r-sided visual loss on unclear date. Dr suspected migraine aura or potential TIA. Recommended starting asa 81mg. Patient refused. No mention of glaucoma.",
"age": 67.43,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "concerning features >> follow \u00ff 7. hx transient visual obscuration DATE_TIME r-sided visual loss (unclear if monocular or binocular) on DATE_TIME - saw dr. PERSON on DATE_TIME, believed most likely migraine aura, but could not rule-out tia, recommended beginning asa 81mg - following with pcp for risk factor optimization - patient does not wish to take aspirin 81mg, not currently taking, does not believe this was a tia - follow-up with dr. PERSON prn \u00ff 8. refractive error - no change in mrx DATE_TIME >> will provide eyeglasses rx DATE_TIME as backup (PERSON)",
"gpt4_summary": "Patient experienced transient r-sided visual loss on unclear date. Dr suspected migraine aura or potential TIA. Recommended starting asa 81mg. Patient refused. No mention of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08169",
"image_path": "slo_fundus_08169.jpg",
"filename": "data_08169.npz",
"report": "64yo female is a glaucoma suspect due to increased cup/disc ratio. Regular testing in the past; current tests are nonspecific for glaucoma. No intervention needed at this time.",
"age": 64.72,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "64 f hx breast ca, tongue ca for f/u glaucoma testing. # glaucoma suspect with increased cup/disc ratio, left > right eye. pt recalls having regular glaucoma testing due to suspicious cupping in the past. [ fhx: no [ cct: 555,569 [ oct DATE_TIME: superior and inftemp thinning od, sup / temp / inf thinning os (stable) [ hvf DATE_TIME: full od, focal supnas defect corresponding to retinal lesion os - although abnormal, the oct is nonspecific for glaucoma, and the visual field test shows no evidence of glaucomatous defects. - no intervention required at this time. continue to monitor. # old posterior vitreous detachment, both eyes. no retinal breaks seen. - discussed retinal detachment precautions. - monitor; return for new symptoms. # NRP, left eye, previously noted - monitor # refractive error. still having some trouble adapting to progressives. - rx given for new glasses. may wish to try standard bifocals or single-vision glasses. rtc 1 year, sooner prn",
"gpt4_summary": "64yo female is a glaucoma suspect due to increased cup/disc ratio. Regular testing in the past; current tests are nonspecific for glaucoma. No intervention needed at this time.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08172",
"image_path": "slo_fundus_08172.jpg",
"filename": "data_08172.npz",
"report": "The patient is suspected of having glaucoma with notable thick cornea & asymmetrical cupping. Mother on latanoprost for high eye pressure. No field loss noted. Normal OCT in left, thin retinal nerve fiber layer in right. Retinas are attached, some posterior vitreous detachment in left eye. The patient also has dry eyes, mild cataracts, and seasonal allergies.",
"age": 61.32,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "glaucoma suspect ou c/d asym, thick cornea--Tcorr is -3.5 OD, -3 os. mom on latanoprost and high iop. hvf 24-2 is wnl ou. oct onh nfl thin OD WNL OS. posterior vitreous detachment os shafer negative, retina attached 360 on dilated eye exam of both eyes. retinal detachment precautions reviewed. PERSON gland dysfunction and dry eyes, bilateral mild ocular surface dryness. warm compresses, lid hygiene. artificial tears as needed. mild age related cataracts, bilateral not visually significant. monitor. seasonal allergy worse in DATE_TIME. gave pt allergy handout. f/u in DATE_TIME for LOCATION, oct, ar/refract. by signing my name below, i, PERSON, acting as a scribe, attest that this documentation has been prepared under the direction and in the presence of PERSON, LOCATION DATE_TIME by signing my name below, i, PERSON, attest that this documentation has been prepared under my direction.",
"gpt4_summary": "The patient is suspected of having glaucoma with notable thick cornea & asymmetrical cupping. Mother on latanoprost for high eye pressure. No field loss noted. Normal OCT in left, thin retinal nerve fiber layer in right. Retinas are attached, some posterior vitreous detachment in left eye. The patient also has dry eyes, mild cataracts, and seasonal allergies.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08174",
"image_path": "slo_fundus_08174.jpg",
"filename": "data_08174.npz",
"report": "Patient with history of eye trauma experienced by blunt force, has normal test results with no glaucoma or retinal tears. Warned of retinal detachment symptoms. Follow-up planned.",
"age": 42.01,
"gender": "male",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "h/o blunt force trauma to the eye (DATE_TIME) pt got punched in the face- was seen on 01/14 at main campus after the event. he is experiencing flashes of light od. Optos, oct and hvf done. oct onh nfl is normal ou. OCT mac WNL. hvf is wnl ou. depressed 360. no retinal tears or holes. warned of RD Sx. will f/u in DATE_TIME. pvd od/ Syneresis os observe. dermatochalasis od>os longstanding. observe. f/u in DATE_TIME dfe.",
"gpt4_summary": "Patient with history of eye trauma experienced by blunt force, has normal test results with no glaucoma or retinal tears. Warned of retinal detachment symptoms. Follow-up planned.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08175",
"image_path": "slo_fundus_08175.jpg",
"filename": "data_08175.npz",
"report": "The patient has been prescribed an ophthalmic solution for both eyes. They have been diagnosed with glaucoma, among other conditions like hypertensive disorder, osteoporosis, and arteriosclerotic heart disease.",
"age": 70.92,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "ophthalmic solution (taking) place 1 drop into each eye every 4 (DATE_TIME. your orders normal orders this visit humphrey visual field - od - right eye oct, optic nerve - od - right eye - cirrus; optic disc; rnfl future labs/procedures complete by expires b-scan ultrasound - os - left eye as directed DATE_TIME condition list as of DATE_TIME hypertensive disorder osteoporosis glaucoma arteriosclerotic heart disease sensorineural hearing loss asthma fracture of humerus hyperlipidemia results summary immunizations administered on date of encounter - DATE_TIME none patient gateway activation information your account is ready to use. LOCATION.",
"gpt4_summary": "The patient has been prescribed an ophthalmic solution for both eyes. They have been diagnosed with glaucoma, among other conditions like hypertensive disorder, osteoporosis, and arteriosclerotic heart disease.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08177",
"image_path": "slo_fundus_08177.jpg",
"filename": "data_08177.npz",
"report": "The clinical note does not provide specific details about the patient's condition, including the presence or absence of glaucoma.",
"age": 35.49,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "spent a total of DATE_TIME personally preparing and caring for this patient (face-to-face and non face-to-face); formulating and finalizing the note, a copy of which was given to the patient DATE_TIME.]",
"gpt4_summary": "The clinical note does not provide specific details about the patient's condition, including the presence or absence of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08179",
"image_path": "slo_fundus_08179.jpg",
"filename": "data_08179.npz",
"report": "54 y.o. female with moderate myopia and bifocals; no significant change in prescription; has two small, flat, non-atypical choroidal nevus; borderline intraocular pressure (IOP) of 22/19; healthy optical nerves; mother uses drops for high IOP. Glaucoma not confirmed.",
"age": 54.65,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "54 y.o. f returns for routine DATE_TIME eye exam # refractive error ou -long standing moderate myopia now with PERSON changes; noting she needs to take glasses off for near work - doing well with current bifocals, no significant change in rx # choroidal nevus x2 os -flat, small size, no atypical features >continue to observe # borderline iop - cct 540/535 - tmax 22/24 - iop 22/19 - optic nerves look healthy - mother uses drops for high iop - hvf DATE_TIME od full os nonspecific defects DATE_TIME od full os full - oct DATE_TIME 81/80 od thin sup os PERSON -- ave wnl DATE_TIME 82/83 od borderline thin sup/inf os wnl > iop borderline at 22/19 ou. observe. photos DATE_TIME follow up DATE_TIME, mrx, dilate. photos",
"gpt4_summary": "54 y.o. female with moderate myopia and bifocals; no significant change in prescription; has two small, flat, non-atypical choroidal nevus; borderline intraocular pressure (IOP) of 22/19; healthy optical nerves; mother uses drops for high IOP. Glaucoma not confirmed.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08183",
"image_path": "slo_fundus_08183.jpg",
"filename": "data_08183.npz",
"report": "Patient has right optic neuropathy, likely traumatic, migraines with aura, intermittent vertigo possibly linked to migraines and disease. Shows signs of conjunctivitis and dry eye syndrome. No glaucoma mentioned.",
"age": 57.18,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "the absence of a relative afferent pupillary defect or dyschromatopsia. relatively mild PERSON thinning is noted on DATE_TIME, though this finding was not seen on her recent outside oct studies, and appears disproportionate to the density of her field loss. subtle temporal pallor is noted in the right optic disc, however. with respect to the patient's headaches and dizziness, her history of intermittent visual obscuration od with retroorbital discomfort and photophobia suggests a component of underlying migraines with aura. consideration may be given to LOCATION's disease in light of her aural fullness, tinnitus, and paroxysmal vertigo, as also previously noted by PERSON in otolaryngology, though she has notably had limited symptomatic relief with appropriate therapy; her imaging has reassuringly not revealed signs of superior canal dehiscence. regardless, she may benefit from further evaluation by neuro-otology for additional diagnostic testing. we also recommended evaluation by her dentist for consideration of a bite guard in light of her tmj dysfunction and persistent headaches, as well as updated refraction, particularly for intermediate distance vision. impression: 1. right optic neuropathy, likely traumatic 2. migraines with aura 3. intermittent vertigo, likely multifactorial secondary to #2 and ?PERSON's disease 4. PERSON dysfunction 5. dry eye syndrome 6. follicular conjunctivits recommendations: 1. dental evaluation for bite guard for suspected tmj dysfunction 2. consider referral to neuro-otology for evaluation of episodic vertigo 3. recommend updated refraction 4. follow-up neuro-ophthalmic examination in DATE_TIME (this note was prepared with the assistance of PERSON, md, neuro-ophthalmology fellow.) PERSON, PERSON neuro-ophthalmology LOCATION PHONE_NUMBER fax PHONE_NUMBER",
"gpt4_summary": "Patient has right optic neuropathy, likely traumatic, migraines with aura, intermittent vertigo possibly linked to migraines and disease. Shows signs of conjunctivitis and dry eye syndrome. No glaucoma mentioned.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08186",
"image_path": "slo_fundus_08186.jpg",
"filename": "data_08186.npz",
"report": "Patient with glaucoma experienced bilateral vision loss due to optic disc edema. Leptomeningeal disease from breast cancer caused optic neuropathy. Brain radiation therapy improved vision OS. Note recommends tapering prednisone.",
"age": 67.33,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "pseudophakia ou, and glaucoma, who developed bilateral vision loss od>os with optic disc edema characterized by hemorrhage and cotton wool spots. she has been found to have leptomeningeal disease from breast cancer, which can cause optic neuropathy related to papilledema or ischemia from infiltration of the subarachnoid space around the anterior optic nerve. steroids initially helped os but the vision progressed in that eye. she has now received whole brain radiation therapy (30 gy) and notes improvement in the brightness of vision os. the exam shows acuities of nlp od and 20/25 os. the right optic nerve has developed atrophy and pallor already, suggesting ischemic injury related to leptomeningeal disease as opposed to papilledema or to optic neuritis. the left optic nerve has improved to 20/25 with radiation therapy, showing inferior greater than superior visual field constriction. i recommended tapering the prednisone over DATE_TIME as she is having side effects and does not have optic neuritis. i will test her vision again in DATE_TIME to monitor her progress. we hope that the radiation and the new chemotherapy will help to maintain her vision in the left eye. \u00ff impression: 1. bilateral optic neuropathy os>od from leptomeningeal breast carcinoma recommendations: 1. taper prednisone: 50 mg x DATE_TIME, 40 mg x DATE_TIME, 20 mg x DATE_TIME, 10 mg x DATE_TIME, skip DATE_TIME, 10 mg x DATE_TIME then off. 2. return in DATE_TIME it is a pleasure to participate in the care of this patient. please do not hesitate to call with questions. ? PERSON, PERSON: greater than half of this DATE_TIME visit was spent counseling the patient on the medical condition or coordinating care.",
"gpt4_summary": "Patient with glaucoma experienced bilateral vision loss due to optic disc edema. Leptomeningeal disease from breast cancer caused optic neuropathy. Brain radiation therapy improved vision OS. Note recommends tapering prednisone.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08187",
"image_path": "slo_fundus_08187.jpg",
"filename": "data_08187.npz",
"report": "61-year-old female chaplain, glaucoma suspect due to increased cup/disc ratio, prevailing more in left than right eye. Risk factors include family history, borderline thinning on Oct, and thin corneas. No actions needed currently.",
"age": 61.7,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "61 f, PERSON chaplain for f/u glaucoma testing. # glaucoma suspect with increased cup/disc ratio, left > right eye [ fhx: father [ cct: 504,505 [ oct DATE_TIME: full od, stable suptemp thinning os [ hvf DATE_TIME: full ou - discussed several risk factors including family history, borderline thinning on oct, and thin corneas. - no intervention required at this time. continue to monitor, but recommended f/u testing in DATE_TIME. rtc DATE_TIME, sooner prn previously: # dry eye disease, both eyes, mild. - reviewed artificial tears ou qid prn. # mild vitreomacular traction, right eye # minimal epiretinal membrane, left eye # posterior vitreous detachment, left eye, with symptomatic floaters. - monitor # cataract, both eyes. minimal and not visually significant in both eyes. - continue to monitor. # refractive error, would like to update glasses. - new rx given to patient.",
"gpt4_summary": "61-year-old female chaplain, glaucoma suspect due to increased cup/disc ratio, prevailing more in left than right eye. Risk factors include family history, borderline thinning on Oct, and thin corneas. No actions needed currently.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08188",
"image_path": "slo_fundus_08188.jpg",
"filename": "data_08188.npz",
"report": "Patient with open angle glaucoma, cataract in right eye and asymptomatic dry eye. Macular degeneration and epiretinal membrane present in both eyes. Elevated intraocular pressure (IOP) noted. Good response to SLT treatment.\n",
"age": 84.4,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "NRP w/ open angle glaucoma ou (od>os), cataract od, pciol os s/p yag ? 1. open angle glaucoma ou: (pt used to see dr. PERSON), lumigan too expensive - cct 587/591 - tmax 27/23 - vf 12/10 possibly worse od, better in DATE_TIME, worse again in 6/12, possibly worse od in 10/13, worse od in DATE_TIME. dp's done DATE_TIME. gdx in DATE_TIME unable od, stable os. oct done in 5/13, worse od in 6/14 s/p slt od DATE_TIME w good response 18 -> 14 s/p slt od in DATE_TIME w good response 24 -> 14 pt stopped using drops, elev iop in 10/15, pt stopped using drops again in 5/16 s/p slt os in DATE_TIME w good response 23 -> 14 - goal iop low teens od, mid teens os. - at goal DATE_TIME ? plan: hold xal ou qhs, c/w cos od bid - monitor od w hvf DATE_TIME. may need additional PERSON if vf worsens further. - rtc in DATE_TIME for iop, hvf and dp's. ? 2. s/p ce/ pciol od DATE_TIME - doing ok. elev iop and blurry vision on pod1, resolved. - pt aware of limited visual potential 2/2 erm od plan: mrx od given in 7/10 ? 3. macular degeneration and erm ou: s/p 23g ppv LOCATION mp ?od DATE_TIME plan: per dr. PERSON. ? 4. pciol + pco os s/p yag DATE_TIME. b&l li61u, 20.5d. - much improved vision ? 5. dry eye - mildly symptomatic. rec lubrication especially qhs to help with am symptoms. ? other: pt is a friend of the ceo of LOCATION, constructing the 3rd building for LOCATION. now retired. pt in LOCATION until DATE_TIME. pt has throat cancer.",
"gpt4_summary": "Patient with open angle glaucoma, cataract in right eye and asymptomatic dry eye. Macular degeneration and epiretinal membrane present in both eyes. Elevated intraocular pressure (IOP) noted. Good response to SLT treatment.\n",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08193",
"image_path": "slo_fundus_08193.jpg",
"filename": "data_08193.npz",
"report": "39-year-old white non-Hispanic female with no diagnosis of glaucoma. Office requests patient to schedule an appointment.",
"age": 39.39,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "a 39 y.o. white, non-hispanic female with no diagnosis of glaucoma. lvm requesting pt call the office to schedule an LOCATION ou, callback numb er provided.",
"gpt4_summary": "39-year-old white non-Hispanic female with no diagnosis of glaucoma. Office requests patient to schedule an appointment.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08195",
"image_path": "slo_fundus_08195.jpg",
"filename": "data_08195.npz",
"report": "Patient on multiple meds including eye drops. Conditions: hypertensive disorder, hypercholesterolemia, allergic rhinitis, nasal congestion. No glaucoma mentioned. No recent immunizations.",
"age": 75.32,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "irbesartan (avapro oral) take 300 mg by mouth DATE_TIME. loratadine oral take by mouth. naproxen sodium (aleve) 220 mg tablet take 220 mg by mouth 2 (two) times a day as needed. polymyxin b sulf-trimethoprim (polytrim) 10,000 unit- 1 mg/ml drop place 1 drop into the left eye 4 (four) times a day. prednisolone acetate (pred LOCATION) 1 % ophthalmic suspension place 1 drop into the left eye 4 (four) times a day. terazosin hcl (terazosin oral) take 3 mg by mouth DATE_TIME. condition list as of DATE_TIME hypertensive disorder hypercholesterolemia seasonal allergic rhinitis nasal congestion results summary immunizations administered on date of encounter - DATE_TIME none",
"gpt4_summary": "Patient on multiple meds including eye drops. Conditions: hypertensive disorder, hypercholesterolemia, allergic rhinitis, nasal congestion. No glaucoma mentioned. No recent immunizations.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08198",
"image_path": "slo_fundus_08198.jpg",
"filename": "data_08198.npz",
"report": "The patient is scheduled for intraocular pressure (IOP) check and ocular coherence tomography (OCT) RNFL/GCC tests, likely for glaucoma monitoring. Tropicamide usage approved.",
"age": 70.23,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "patient's request on DATE_TIME. -rtc in DATE_TIME with iop check and oct rnfl/gcc ou (ok to use tropicamide 0.5% to obtain good view), sooner prn. the information above was documented by PERSON as a scribe for PERSON on DATE_TIME.",
"gpt4_summary": "The patient is scheduled for intraocular pressure (IOP) check and ocular coherence tomography (OCT) RNFL/GCC tests, likely for glaucoma monitoring. Tropicamide usage approved.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08202",
"image_path": "slo_fundus_08202.jpg",
"filename": "data_08202.npz",
"report": "The 45-year-old male patient has ocular hypertension and is possibly at a pre-perimetric glaucoma stage. He is not regular with his timolol eye drops. There's also allergic conjunctivitis, dry eyes, and refractive error.",
"age": 45.9,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "45 y.o. man presents for follow up 1. ocular htn: has not been compliant with drops recently (timolol) and taking them at DATE_TIME instead of the morning. humphrey visual field full ou, optical coherence tomography shows thinning ou DATE_TIME that is stable. possibly pre-perimetric glaucoma. pressure DATE_TIME is too high. -continue timolol qd ou in am every day -if pressures creep into DATE_TIME, then would add xalatan ou qhs -return for pressure check in 4-5 mos dfe: 3/20 gonio: DATE_TIME tmax: 28/32 cct: 534, 534 hvf: 3/20 oct: 3/20 famhx: no 2. allergic conjunctivitis ou: stable; having some dryness too; occasionally gets pingueculitis -better on zaditor -artificial tears prn \u00ff 3. refractive error: wants a new rx for glasses - old ones are scratched -give new rx for glasses",
"gpt4_summary": "The 45-year-old male patient has ocular hypertension and is possibly at a pre-perimetric glaucoma stage. He is not regular with his timolol eye drops. There's also allergic conjunctivitis, dry eyes, and refractive error.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08204",
"image_path": "slo_fundus_08204.jpg",
"filename": "data_08204.npz",
"report": "Ms. PERSON, a retail manager, has decreased peripheral vision and a history of a stable arachnoid cyst in pituitary area. She's suspected to have optic neuropathy due to cyst. No glaucoma mentioned.",
"age": 42.94,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "formulation: ms. PERSON is a retail store manager here for evaluation of her decreased peripheral vision. she has history of arachnoid cyst in pituitary area that is being follow and has been stable in size (last mri DATE_TIME). on the exam DATE_TIME, she had mild temporal pallor of her optic nerves bilaterally. the visual field results were not reliable. there was loss of ganglionic cell layer in macula on oct. thus, there appears to be an optic neuropathy, which could the result of compression from the arachnoid cyst. we will follow her in DATE_TIME and re-evaluate her to make sure the findings are not progressive. impression: 1. possible compression optic neuropathy from pituitary arachnoid cyst plan: 1. follow up in DATE_TIME. 2. consider repeat oct during re-evaluation PERSON neuro-ophthalmology LOCATION PHONE_NUMBER fax PHONE_NUMBER",
"gpt4_summary": "Ms. PERSON, a retail manager, has decreased peripheral vision and a history of a stable arachnoid cyst in pituitary area. She's suspected to have optic neuropathy due to cyst. No glaucoma mentioned.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08208",
"image_path": "slo_fundus_08208.jpg",
"filename": "data_08208.npz",
"report": "The patient is a glaucoma suspect based on increased c/d ratio and family history. Mild cataract is present but not visually significant. Patient's IOP is controlled. A new glasses prescription was given.",
"age": 63.49,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "1. glaucoma suspect based on inc c:d ratio ou fhx + mom and mgm with glaucoma hvf od: reliable, mild ins defect (fluctuates in location but no worse in severity) hvf os reliable and full oct borderline os, PERSON dp stable gonio open ou cct average 546,548 iop controlled, observe 2. refractive error: a prescription for new glasses was given to the patient DATE_TIME. 3. mild cataract is present ou that is not visually significant. observation at this time was recommended. DATE_TIME, mrx, iop, hvf, LOCATION, oct and dp",
"gpt4_summary": "The patient is a glaucoma suspect based on increased c/d ratio and family history. Mild cataract is present but not visually significant. Patient's IOP is controlled. A new glasses prescription was given.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08212",
"image_path": "slo_fundus_08212.jpg",
"filename": "data_08212.npz",
"report": "65 y.o. male, glaucoma suspect, with no changes in vision since last visit. Also has bipolar disorder, hyperlipidemia, obesity, hypertension, and is a former smoker. No pain or discomfort in eyes. Stable thinning, no significant cataracts or vision issues. 'Sunken eyes' noticed, possibly due to dermatochalasis.",
"age": 65.15,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "65 y.o. male presents for glaucoma suspect follow-up last visit with me: DATE_TIME pohx: glaucoma at last eye exam, feels eyes 'sunken in' and family notes it too pmhx: bipolar disorder, hyperlipidemia, obesity, hypertension, cad, former smoker hpi DATE_TIME: pt here for glaucoma suspect ou pt denies any visual changes since last visit pt denies any new flashes or floaters ou, no pain, ou feel comfortable ocular medications: none assessment/plan: # glaucoma suspect - glaucoma suspect based on increased cup/disc - iop - 12/11 - tmax - 17/17 here DATE_TIME - cct - 520/520 - thin ou - c/d - 0.8. 0.75 - gonio - refused at last visit - family history - none per patient - last hvf performed - DATE_TIME - full ou, DATE_TIME - full ou - last oct rnfl performed - DATE_TIME - stable LOCATION thinning od > os - DATE_TIME - non-specific LOCATION thinning, ou, large disc area ou - baseline fundus photos obtained - DATE_TIME - dilated optic nerve exam performed ou DATE_TIME - discussed potential for progressive irreversible vision loss due to glaucomatous optic neuropathy. - return in DATE_TIME with hvf 24-2, iop check # cataract, not visually significant # myopia with astigmatism and presbyopia - mild cataract is present that is not visually significant. - bcva 20/20, 20/20 - observation of cataracts at this time was recommended. - will try new prescription for glasses and if continuing to bother patient will consider cataract extraction surgery # dermatochalasis/steatoblepharon - family is telling him to have 'sunken eyes', likely from relative positioning of brow and dermatochalasis, no concerning orbital signs - symmetric hertel's DATE_TIME - not visually significant - observe rtc for glaucoma testing in DATE_TIME with hvf 24-2, iop check, refract/dilate if allows PERSON, md",
"gpt4_summary": "65 y.o. male, glaucoma suspect, with no changes in vision since last visit. Also has bipolar disorder, hyperlipidemia, obesity, hypertension, and is a former smoker. No pain or discomfort in eyes. Stable thinning, no significant cataracts or vision issues. 'Sunken eyes' noticed, possibly due to dermatochalasis.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08213",
"image_path": "slo_fundus_08213.jpg",
"filename": "data_08213.npz",
"report": "Patient suspected of glaucoma. Normal optic nerve, visual fields. Tmax at 22, low corneal hysteresis (8.8/8.6), central corneal thickness 520/515. No procedures/medication history. Slightly large nerves, intraocular pressure around 20.",
"age": 56.41,
"gender": "male",
"race": "black",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "married or partnered",
"note": "first seen by dr. PERSON on DATE_TIME diagnosis: glaucoma suspect target iop: / , tmax: 22 (DATE_TIME) / 22 (DATE_TIME) central corneal thickness: 525, 527, 529 / 514, 515, 516 corneal hysteresis: 8.8/8.6 gonioscopy: scleral spur, light pigment refractive error: od . . / os . . optic nerve findings on initial visit right eye: normal optic nerve findings on initial visit left eye: normal visual fields on initial visit right eye: normal visual fields on initial visit left eye: normal medication history and intolerances at first visit: none glaucoma procedures right eye: glaucoma procedures left eye: other eye procedures right eye: other eye procedures left eye: other eye problems right eye: other eye problems left eye: family history: mother and younger sister (vision loss at young age) steroids: no trauma: no asthma: no other medical history and problems: none initial note: large cup:disc ratio, slightly large nerves, intraocular pressure around 20, mother with glaucoma and good vision, low corneal hysteresis (8.8 and 8.6) and central corneal thickness 520/515). could consider selective laser trabeculoplasty sooner than later. plan: slightly large nerves, large cups, borderline iop; check in DATE_TIME with testing and dilation. PERSON scribing for dr. PERSON (DATE_TIME, DATE_TIME) i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "Patient suspected of glaucoma. Normal optic nerve, visual fields. Tmax at 22, low corneal hysteresis (8.8/8.6), central corneal thickness 520/515. No procedures/medication history. Slightly large nerves, intraocular pressure around 20.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08217",
"image_path": "slo_fundus_08217.jpg",
"filename": "data_08217.npz",
"report": "The patient has posterior optic neuropathy likely due to trauma, pellucid marginal degeneration, cataract, myopia with astigmatism, and presbyopia. No signs of glaucoma mentioned.",
"age": 56.45,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "foveal sensitivity and peripheral defects, consistent with posterior optic neuropathy (LOCATION), and given the onset after the fall this is likely traumatic - recommend patient wear polycarbonate lenses for protection - recommend he follow-up with neuro-op service for evaluation and information on prognosis although prognosis is guarded and vision will not likely improve significantly - recommend return to me in DATE_TIME with hvf 24-2 and oct rnfl, no dilation # headaches - no ocular cause of headaches seen on exam DATE_TIME - can follow-up with neurology dr. PERSON as scheduled DATE_TIME - has had concussion in the past, now feels like he has a migraine all day and night, having difficulty sleeping - no recommendations given DATE_TIME to patient, pain is not around eye but behind left temple # pellucid marginal degeneration os > od - visual acuity was 20/40 previously with glasses and 20/50 with contacts os - sees well with PERSON or glasses - recommend polycarbonate lenses as above # cataract, not visually significant # myopia with astigmatism and presbyopia (high astigmatism from pmd as above) - mild cataract is present that is not visually significant. - bcva 20/20, DATE_TIME/cf DATE_TIME - observation of cataracts at this time was recommended. rtc to neuro-op - appointment to be scheduled, referral placed DATE_TIME rtc to me in DATE_TIME with hvf 24-2 and oct rnfl, no dilation, can refract if pinhole improves os PERSON, md",
"gpt4_summary": "The patient has posterior optic neuropathy likely due to trauma, pellucid marginal degeneration, cataract, myopia with astigmatism, and presbyopia. No signs of glaucoma mentioned.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08223",
"image_path": "slo_fundus_08223.jpg",
"filename": "data_08223.npz",
"report": "The patient is suspected of glaucoma based on visual field. Initial tests show mostly healthy nerves, thinning on the right eye's optic nerve, inferior nasal step on right eye, but all normal for left eye. No medications being used.",
"age": 73.58,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "first seen by PERSON PERSON on DATE_TIME diagnosis: glaucoma suspect based on humphrey visual field; referred by dr. PERSON target iop: / , tmax: ( ) / ( ) central corneal thickness: 530 / 531 gonioscopy: cbb refractive error: LOCATION . -0.75 . 100 / os +3.50 . -1.00 . 087 optic nerve findings on initial visit right eye: superior thinning optic nerve findings on initial visit left eye: normal visual fields on initial visit right eye: inferior nasal step visual fields on initial visit left eye: normal medications being used at first visit: none medication intolerances:none glaucoma procedures right eye: none glaucoma procedures left eye: none other eye procedures right eye: none other eye procedures left eye: none other eye problems right eye: none other eye problems left eye: none family history: none steroids: intermittent (not for a long time) trauma: none asthma: intermittent (not active-- pt suspicious of prior diagnosis) other medical history and problems: cabg x 4, cardiac stent initial note: referred by PERSON for glaucoma suspect both eyes. prior testing reveals superior thinning and an inferior nasal step on humphrey visual field right eye despite the nerve appearing mostly healthy and intraocular pressure 10 on no medications. all testing normal left eye. right eye with inferior nasal step and corresponding thinning on optical coherence tomography. however the pressures are lowand the nerves look acceptable both eyes (though small and sl tilt). unclear if this defect is chronic/congenital or new. patient to bring in old records. monitor off drops. plan: continue to monitor off drops. patient to bring old records of testing. repeat optical coherence tomography and humphrey visual field in DATE_TIME.",
"gpt4_summary": "The patient is suspected of glaucoma based on visual field. Initial tests show mostly healthy nerves, thinning on the right eye's optic nerve, inferior nasal step on right eye, but all normal for left eye. No medications being used.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08224",
"image_path": "slo_fundus_08224.jpg",
"filename": "data_08224.npz",
"report": "Patient has choroidal melanoma in right eye and severe glaucoma in left eye. Right eye's intraocular pressure is 30, left eye's is 27/12. Surgery recommended. Currently using diamox.",
"age": 86.01,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "first seen by dr. PERSON on DATE_TIME, aronow patient diagnosis: choroidal melanoma right eye with intraocular pressure 27/12 target iop: / , tmax: ( ) / ( ) central corneal thickness: 485 / 653 gonioscopy: refractive error: PERSON. -3.25. 100 / os +0.50. DATE_TIME. 035 optic nerve findings on initial visit right eye: optic nerve findings on initial visit left eye: thin throughout visual fields on initial visit right eye: visual fields on initial visit left eye: superior arcuate and inferior arcuate dense medication history and intolerances at first visit: PERSON, combigan latanoprost diamox glaucoma procedures right eye: glaucoma procedures left eye: other eye procedures right eye: cataract extraction other eye procedures left eye: cataract extraction, dsek other eye problems right eye: other eye problems left eye: family history: steroids: trauma: asthma: other medical history and problems: plan: severe glaucoma left eye but intraocular pressure is low and monitored in LOCATION. right eye intraocular pressure is 30, but appears to have active melanoma. seeing aronow DATE_TIME who recommends enucleation. tolerating diamox and he can decide if he would like to continue or stop until surgery. intraocular pressure left eye target should be low",
"gpt4_summary": "Patient has choroidal melanoma in right eye and severe glaucoma in left eye. Right eye's intraocular pressure is 30, left eye's is 27/12. Surgery recommended. Currently using diamox.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08226",
"image_path": "slo_fundus_08226.jpg",
"filename": "data_08226.npz",
"report": "Patient has eye pressure in right and left. Glaucoma indicated through cupped out c/d ratios of 0.85 and 1.0. Restriction and deficiencies in visual fields.",
"age": 83.98,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "pressure 19 07 tonometry #2 (ta ub, DATE_TIME) right left pressure DATE_TIME gonioscopy right left superior c/d 35f c/d 35f, pas inferior c/d 35f c/d 35f pupils pupils right perrl left LOCATION visual fields left right restrictions partial superior temporal, inferior temporal, superior nasal, inferior nasal deficiencies partial superior temporal, inferior temporal, superior nasal, inferior nasal deficiencies extraocular movement right left result full, ortho full, ortho neuro/psych oriented x3: yes mood/affect: normal slit lamp and fundus exam slit lamp exam right left lids/lashes ll lagophthalmos ll lagophthalmos conjunctiva/sclera normal tube and plate well covered, trabeculectomy LOCATION with quiet bleb, trace microcysts cornea dry, 1+ diffuse pee dry pee anterior chamber normal quiet, tube in good position in LOCATION PERSON normal, pxf material, tid at margin LOCATION, ik touch superotemporal, peripheral LOCATION, tid lens posterior chamber intraocular lens, pseudoexfoliation posterior chamber intraocular lens, pseudoexfoliation vitreous normal normal fundus exam right left disc thinning inferiorly, ppa ppa, cupped out c/d ratio 0.85 1.0 macula normal normal refraction wearing rx sphere cylinder axis right -PHONE_NUMBERE left -0.50 -0.75 73",
"gpt4_summary": "Patient has eye pressure in right and left. Glaucoma indicated through cupped out c/d ratios of 0.85 and 1.0. Restriction and deficiencies in visual fields.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08227",
"image_path": "slo_fundus_08227.jpg",
"filename": "data_08227.npz",
"report": "The patient has persistently high intraocular pressure which suggests they have glaucoma. Risks of laser treatment were discussed. If pressure remains high, possible treatments include SLT or Trab 360.",
"age": 31.79,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "needed. -contact lens hygiene was reviewed on DATE_TIME. -long discussion with patient on DATE_TIME: given iop persistently above goal od, we will proceed with LOCATION. risks, benefits, and alternatives to laser were discussed with the patient, including the potential risk of infection, bleeding, loss of vision, loss of eye, double vision, need for further surgery or laser, retinal detachment, change in glasses and reading glasses. no guarantees given. questions answered. consents signed. *** asa/blood thinners *** increased risk of complications due to implants/special equipment needed -- *** preferred anesthesia -- *** diabetic -- no -rtc on DATE_TIME with iop check, hvf, and oct rnfl/gcc ou, sooner prn. if iop still above goal od next visit, we can consider booking slt od (if iop above goal but hvf stable) versus trab 360 od (if iop above goal and hvf significantly progressed versus adding rhopressa qhs ou. the information above was documented by PERSON as a scribe for PERSON on DATE_TIME.",
"gpt4_summary": "The patient has persistently high intraocular pressure which suggests they have glaucoma. Risks of laser treatment were discussed. If pressure remains high, possible treatments include SLT or Trab 360.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08228",
"image_path": "slo_fundus_08228.jpg",
"filename": "data_08228.npz",
"report": "Retired physician has undergone surgery for elevated intraocular pressure (IOP); goals of <=10mmHg in the right eye and <=9mmHg in left eye. Currently off glaucoma meds. Further monitoring planned.",
"age": 84.96,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "a retired physician. attending's plan: -goal intraocular pressure less than or equal to 10 mmhg, right eye. -goal intraocular pressure less than or equal to 09 mmhg, left eye. -iop *** goal od and *** goal os on DATE_TIME s/p phaco/ecp/kdb ou and off glaucoma medications. -continue close monitoring off glaucoma medications. -preservative-free artificial tears as needed. -patient admits to snoring sporadically (?possible ltg component given progression at normal PERSON), but his wife denied it is consistent. if further progression, will re-visit DATE_TIME. -good phaco/migs candidate when patient ready, but currently patient happy with vision. -long discussion with patient on DATE_TIME: we discussed surgical intervention given iop slightly above goal os and new disc hemorrhage os inferiorly with iop of 10 mmhg; he would be a good candidate for phaco/trab os first versus phaco/ecp/kdb os. after extensively discussing pros/cons of each procedure, we proceeded with phaco/ecp/kdb os (attending case) on DATE_TIME knowing further intervention may be needed in the future. -long discussion with patient on DATE_TIME: given good response os and wish for best vision od, we proceeded with phaco/ecp/kdb od on DATE_TIME. -rtc in DATE_TIME for iop check, hvf, dilation, and oct rnfl/gcc ou, sooner prn. we'll attempt zioptan qhs ou in future if iop above goal and/or ocudose after surgery if iop control needed (and we'll try to spare him rhopressa). the information above was documented by PERSON as a scribe for PERSON on DATE_TIME.",
"gpt4_summary": "Retired physician has undergone surgery for elevated intraocular pressure (IOP); goals of <=10mmHg in the right eye and <=9mmHg in left eye. Currently off glaucoma meds. Further monitoring planned.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08229",
"image_path": "slo_fundus_08229.jpg",
"filename": "data_08229.npz",
"report": "The patient has been diagnosed with normal tension glaucoma, moderate in the right eye, and mild in the left eye. No prior glaucoma surgery recorded. The patient needs intraocular pressure of approximately 12 in both eyes.",
"age": 54.53,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "# first seen by PERSON on DATE_TIME diagnosis: normal tension glaucoma, moderate right eye and mild left eye ttarget: / , tmax: ( ) / ( ) cct: / gonioscopy: open both eyes refractive error: od -3.00. -0.75. 168 / os -3.75. sphere. optic nerve: cup:disc ratio 0.85 both eyes with disc heme in both eyes rnfl oct: borderline thinning both eyes (average retinal nerve fiber layer 76 um right eye and 81 um left eye) vf: inferior arcuate right eye (md -11.82 db), inferior paracentral defect left eye (md -4.42 db) med intolerances: on latanoprost prior glaucoma surgery: none od / none os other eye surgery: none od/ none PERSON: ? uncle (went blind)/ steroids: none/ asthma: none/ trauma: none # pvd right eye -shafer neg - retinal detachment precautions reviewed pmhx: proteinuria (unclear etiology, on PERSON), osa (on cpap) plan: primary open angle glaucoma both eyes drance heme DATE_TIME needs intraocular pressure close to 12 both eyes continue ltn. also add timolol bid rtc DATE_TIME intraocular pressure check, dilation, dp and repeat humphrey visual field diagnosis of glaucoma/glaucoma suspect discussed with patient - review of natural history and management options discussed. importance of lifelong follow up and adherence to treatments discussed in order to lower risk of permanent vision loss/blindness from glaucoma. all questions answered. i spent DATE_TIME with the patient, more than half of which was spent on counseling and coordination of care for this patient's glaucoma",
"gpt4_summary": "The patient has been diagnosed with normal tension glaucoma, moderate in the right eye, and mild in the left eye. No prior glaucoma surgery recorded. The patient needs intraocular pressure of approximately 12 in both eyes.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08232",
"image_path": "slo_fundus_08232.jpg",
"filename": "data_08232.npz",
"report": "Patient shows mild refractive change, posterior vitreous detachment, cataract, and is glaucoma suspect (due to cup asymmetry) with stable pressure. No family history or symptoms of glaucoma.",
"age": 69.11,
"gender": "male",
"race": "white",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "married or partnered",
"note": "last seen by me DATE_TIME) refractive: mild change - give new rx for glasses 2) posterior vitreous detachment od: seen in past by vavvas with no breaks found. stable 3) glaucoma suspect (cupping os>od): pressures have been fine. the visual fields have been reassuring but DATE_TIME are low quality os. the optical coherence tomography shows larger nerve os with cupping but no thinning. pachymetry is slightly thin. there is no family hx of glaucoma. i think this is physiologic cup asymmetry and is not worrisome. - repeat humphrey visual field alone in DATE_TIME to be sure - otherwise return DATE_TIME for dilation, humphrey visual field and optical coherence tomography - needs gonio next time dfe: 11/21 vf: 11/21 DATE_TIME gonio: tmax: 15, 15 cct: 513, 530 fhx: no 4) cataracts ou: mild with no symptoms. DATE_TIME driving is fine. -follow 5) PERSON's os?: not seen DATE_TIME on exam. thought to be from carotid dissection DATE_TIME. -follow",
"gpt4_summary": "Patient shows mild refractive change, posterior vitreous detachment, cataract, and is glaucoma suspect (due to cup asymmetry) with stable pressure. No family history or symptoms of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08233",
"image_path": "slo_fundus_08233.jpg",
"filename": "data_08233.npz",
"report": "Patient has cataract in left eye, glaucoma in both eyes controlled with Xalatan. Also has age-related macular degeneration (AMD) in both eyes and sup arcuate ou.",
"age": 75.47,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "imp: pciol od cataract os poag ou; PERSON; iop controlled with xalatan; unremarkable oct of rnfl, but hvf --first here DATE_TIME--suggests sup arcuate ou amd ou plan: 4 mo dilated exam/refraction plus oct of rnfl and PERSON; hvf repeat",
"gpt4_summary": "Patient has cataract in left eye, glaucoma in both eyes controlled with Xalatan. Also has age-related macular degeneration (AMD) in both eyes and sup arcuate ou.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08234",
"image_path": "slo_fundus_08234.jpg",
"filename": "data_08234.npz",
"report": "The patient has visual field loss but stable OCT, indicating close monitoring. Mild guttata are stable. History of retinal person with adjacent fluid and demarcation line. Dry eyes present.",
"age": 76.48,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "visual field with sn losses, but oct stable. continue to monitor closely. \u00ff\u00ff 5. mild guttata ou -stable cct DATE_TIME: 532/535 \u00ff\u00ff 6. hx retinal PERSON, with small cuff of fluid surrounding, and adjacent demarcation line just anterior to this. asx >> rd precautions reviewed 7. dry eyes ou - continue artificial tears 3-4 times DATE_TIME - start artificial tear ointment at bedtime - warm compresses",
"gpt4_summary": "The patient has visual field loss but stable OCT, indicating close monitoring. Mild guttata are stable. History of retinal person with adjacent fluid and demarcation line. Dry eyes present.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08236",
"image_path": "slo_fundus_08236.jpg",
"filename": "data_08236.npz",
"report": "The 49 y.o. female patient, with history of Graves disease and breast cancer, has no signs of optic neuropathy or glaucoma. She reported diplopia when tired, and has dermatochalasis, potentially needing surgery.",
"age": 50.01,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "49 y.o. female presents for a new patient visit referred by endocrinologist PERSON PERSON chang, as she is considering undergoing radioactive iodine therapy. she has a past medical history of graves disease and breast cancer s/p bilateral mastectomy 1. graves disease diagnosed DATE_TIME with mild graves PERSON methimazole, planning for possible radioactive iodine treatment disease - 20/20 ou, no dyschromatopsia - mild lid retraction/flare ou, no evidence of optic neuropathy - oct rnfl DATE_TIME: wnl ou - hvf DATE_TIME: reliable and full ou - previously tried selenium 100 mcg po bid (started DATE_TIME), but no longer taking since no benefit noted - dr. PERSON questioning whether would benefit from corticosteroid treatment before and during rai treatment - never smoker - reports vertical binocular diplopia when tired, not likely graves related - continue artificial tears prn - no signs of optic neuropathy, does not need to add corticosteroid treatment if pursuing rai 2. diplopia - patient notes vertical diplopia when tired, has had prism in her glasses since DATE_TIME - small right hypertropia noted on alternate cover, 3pd at distance - patient has a left head tilt on exam DATE_TIME and on her driver's license photo, could be due to congenital 4th nerve palsy with mild decompensation versus other etiologies - observe for now 3. dermatochalasis - patient notes fullness of upper and lower lids ou, interested in possible surgical correction - in light of mild lid retraction would recommend further evaluation with oculoplastics service in the next DATE_TIME, after her thyroid levels have stabilized rtc to oculoplastics service in DATE_TIME (after rai/thyroid labs have stabilized) to discuss lid procedures for dermatochalasis rtc DATE_TIME or sooner for routine exam with me PERSON, pgy-4 patient seen and discussed with resident. agree with assessment and plan. PERSON, md",
"gpt4_summary": "The 49 y.o. female patient, with history of Graves disease and breast cancer, has no signs of optic neuropathy or glaucoma. She reported diplopia when tired, and has dermatochalasis, potentially needing surgery.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08238",
"image_path": "slo_fundus_08238.jpg",
"filename": "data_08238.npz",
"report": "Patient has posterior vitreous detachment, dermatochalasis of upper eyelids, choroidal nevus in left eye, and dry eye syndrome. There are ongoing treatments for glaucoma and cataract.",
"age": 65.52,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "eye -follow-up with dr. PERSON for cornea care. 5. posterior vitreous detachment, both eyes -retinal detachment precautions were reviewed with the patient. DATE_TIME/o breast cancer w/ tamoxifen use, d/c DATE_TIME 7. dermatochalasis of upper eyelids, both eyes -follow-up with dr. PERSON for eyelid care. 8. choroidal nevus, left eye 9. dry eye syndrome, both eyes -preservative-free artificial tears as needed. 10. social/systemic issues: referred to clinic by dr. PERSON. patient is a retired nurse from PERSON. attending's plan: -goal intraocular pressure less than or equal to *** mmhg, right eye. -goal intraocular pressure less than or equal to *** mmhg, left eye. -iop *** goal od and *** goal os on DATE_TIME on ***. -retinal detachment precautions were reviewed with the patient. -preservative-free artificial tears as needed. -follow-up with dr. PERSON for cornea care. -follow-up with dr. PERSON for eyelid care. -rtc in DATE_TIME with iop check, ***, dilation, and disc photos ou, sooner prn. i spent DATE_TIME on care for the patient (face-to-face and non-face-to-face), more than half of which was spent on counseling and coordination of care for this patient's glaucoma and cataract. the information above was documented by PERSON as a scribe for PERSON on DATE_TIME.",
"gpt4_summary": "Patient has posterior vitreous detachment, dermatochalasis of upper eyelids, choroidal nevus in left eye, and dry eye syndrome. There are ongoing treatments for glaucoma and cataract.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08240",
"image_path": "slo_fundus_08240.jpg",
"filename": "data_08240.npz",
"report": "Patient has mild, angle recession glaucoma & amblyopia in left eye, caused by metal-induced trauma. Also, has asthma but tolerates timolol well for glaucoma. Plan to stop timolol & monitor IOP.",
"age": 44.01,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "first seen by dr. PERSON on DATE_TIME, former patient of song angle recession glaucoma left eye, mild, amblyopia left eye, ruptured globe left eye (metal in ac), DATE_TIME target iop: DATE_TIME, tmax: 20 (DATE_TIME) / 20 (DATE_TIME) central corneal thickness: 520 / 508 gonioscopy: inferior angle recession os with pas in inferotemporal quadrant as a result of trauma refractive error: od -PHONE_NUMBER / os +0.00. LOCATION. 167 optic nerve findings on initial visit right eye: healthy optic nerve findings on initial visit left eye:oct-rnfl (87/82) with inf thinning visual fields on initial visit right eye: normal visual fields on initial visit left eye: normal medication history and intolerances: timolol on visit with df (has tolerated despite asthma) glaucoma procedures right eye : glaucoma procedures left eye : other eye procedures: amblyopia left eye family history: steroids: trauma: other history and problems: asthma (uses albuterol inhaler) plan: stop timolol, iop okay. monitor in DATE_TIME.",
"gpt4_summary": "Patient has mild, angle recession glaucoma & amblyopia in left eye, caused by metal-induced trauma. Also, has asthma but tolerates timolol well for glaucoma. Plan to stop timolol & monitor IOP.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08246",
"image_path": "slo_fundus_08246.jpg",
"filename": "data_08246.npz",
"report": "Mr. PERSON has mild nonproliferative diabetic retinopathy in both eyes, central retinal vein occlusion in the right eye, and bilateral nuclear sclerotic cataract. Glaucoma presence is negative.",
"age": 58.48,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "mr. PERSON is a DATE_TIME. male with 1. both eyes affected by mild nonproliferative diabetic retinopathy with macular edema, associated with type 2 diabetes mellitus 2. central retinal vein occlusion with macular edema of right eye 3. nuclear sclerotic cataract, bilateral vision readings for this visit: va distance LOCATION distance cc va near LOCATION near cc iop right 20/20-2 ph ph 19 left 20/20 ph ph 19 referred by dr. PERSON for continued care assessment 1. sup. PERSON with PERSON scatter laser superior LOCATION. 3.20.18 s/p multiple avastin last DATE_TIME - va is stable 20/25, iop DATE_TIME DATE_TIME: me os stable compared to his previous scan - oct 11.15.19: improved edema compared to DATE_TIME. continue to monitor for now 2. mild PERSON ou - a1c: pt doesn't remember (DATE_TIME) - insulin dependent. 3. asymmetric high c/d ratio od>os - negative glaucoma family history - iop is 21/19 - saw dr. PERSON DATE_TIME who started pt on latanoprost - dr. PERSON also recommended slt - discussed with pt that LOCATION is very slightly preferable to latanoprost as latanoprost may increase edema, but both good options for iop control - emphasized need for regular f/u with dr. PERSON plan - monitor for now f/u with dr. PERSON as scheduled 2.2020 f/u with PERSON PERSON as recommended return to clinic in DATE_TIME, sooner as needed, with oct. the above note was recorded by PERSON as a scribe for PERSON demetrios PERSON, PERSON on DATE_TIME at DATE_TIME i attest that i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate. demetrios PERSON, DATE_TIME.",
"gpt4_summary": "Mr. PERSON has mild nonproliferative diabetic retinopathy in both eyes, central retinal vein occlusion in the right eye, and bilateral nuclear sclerotic cataract. Glaucoma presence is negative.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08248",
"image_path": "slo_fundus_08248.jpg",
"filename": "data_08248.npz",
"report": "The note reveals visually significant issues in both eyes on certain dates, with posterior vitreous detachment in the left eye. Patient suffers from dry eye syndrome. Goal intraocular pressure is set at less than or equal to 17 mmHg in both eyes.",
"age": 64.5,
"gender": "female",
"race": "white",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "unknown",
"note": "DATE_TIME.','-potentially visually-significant, both eyes as of DATE_TIME.','-visually-significant, right eye as of DATE_TIME.','-visually-significant, left eye as of DATE_TIME.','-visually-significant, both eyes as of DATE_TIME.','-not visually-significant, right eye as of DATE_TIME.','-not visually-significant, left eye as of DATE_TIME.','-not visually-significant, both eyes as of DATE_TIME.','-stable.'} 3. posterior vitreous detachment, left eye -retinal detachment precautions were reviewed with the patient. 4. s/PERSON, both eyes 5. dry eye syndrome, both eyes -preservative-free artificial tears as needed. 6. social/systemic issues: seen formerly by dr. PERSON. attending's plan: -goal intraocular pressure {goal pressure:19197::'~','less than or equal to','=','greater than or equal to'} 17 mmhg, right eye. -goal intraocular pressure {goal pressure:19197::'~','less than or equal to','=','greater than or equal to'} 17 mmhg, left eye. -iop {goal:19197::'at','above','well above'} goal od and {goal:19197::'at','above','well above'} goal os on DATE_TIME on off glaucoma medications. DATE_TIME plus others oct",
"gpt4_summary": "The note reveals visually significant issues in both eyes on certain dates, with posterior vitreous detachment in the left eye. Patient suffers from dry eye syndrome. Goal intraocular pressure is set at less than or equal to 17 mmHg in both eyes.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08249",
"image_path": "slo_fundus_08249.jpg",
"filename": "data_08249.npz",
"report": "Patient has early-stage cataracts in both eyes with symptoms of glare. They also have choroidal nevi, more significant in the left eye. No mention of glaucoma.",
"age": 57.96,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "wears pals for better quality of vision \u00ff 5. cataracts ou - early sx of glare, ctm 6. choroidal nevi os>od cox, pgy-4 i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow. i have reviewed the resident/fellow's notes and made any necessary changes.",
"gpt4_summary": "Patient has early-stage cataracts in both eyes with symptoms of glare. They also have choroidal nevi, more significant in the left eye. No mention of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08250",
"image_path": "slo_fundus_08250.jpg",
"filename": "data_08250.npz",
"report": "The patient had cataract surgery and yag pc, with dry macular detected by OCT. No signs of glaucoma in RNFL OU. Requires glasses prescription.",
"age": 79.61,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "imp: s/p cataract surgery ou and yag pc os in LOCATION macular PERSON ou--dry by oct now central LOCATION sec to PERSON; normal oct of rnfl ou refr error plan: rx=m glasses",
"gpt4_summary": "The patient had cataract surgery and yag pc, with dry macular detected by OCT. No signs of glaucoma in RNFL OU. Requires glasses prescription.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08251",
"image_path": "slo_fundus_08251.jpg",
"filename": "data_08251.npz",
"report": "The patient has severe dry eye syndrome, is using refresh and at gel for symptoms. Monitoring for eye strain despite new prescription. Glaucoma medication might cause side effects. Recommended restasis and humidifier.",
"age": 62.96,
"gender": "female",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "periph on temporal side >> monitor # eye strain - despite new mrx recently >> consider re-eval mrx soon # dry eye - severe on exam DATE_TIME, very symptomatic - already using refresh PERSON and at gel qhs - will hold off on punctal plugs for now as may keep glaucoma meds against eye for longer and cause side effects >> rec pfat gel qid ou >> rec restasis bid ou >> rec humidifier daily # refractive error >> mrx provided previously # dry eye syndrome >> continue artificial tears, gel drop qid ou rtc 3 mo no dilate surface check PERSON, md, mph",
"gpt4_summary": "The patient has severe dry eye syndrome, is using refresh and at gel for symptoms. Monitoring for eye strain despite new prescription. Glaucoma medication might cause side effects. Recommended restasis and humidifier.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08252",
"image_path": "slo_fundus_08252.jpg",
"filename": "data_08252.npz",
"report": "78-year-old patient with history of COPD, hypertension, and hyperlipidemia has visually significant cataract in left eye, affecting daily activities. Patient has agreed to proceed with cataract surgery and potential risks including infection, bleeding, vision loss, and glaucoma were discussed. Astigmatism and ocular hypertension noted, but eye pressure excellent on latanoprost. Early signs of primary open-angle glaucoma were also observed.",
"age": 78.68,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "78 y.o. est pt, hx of LOCATION, LOCATION, PERSON, copd, htn, hyperlipidemia, mild ashtma, pituitary cyst followed by dr. PERSON wishes to see me instead as his wife is a patient of mine PERSON great, happy with result combined cataract left - visually significant and affecting activities of DATE_TIME living - dilates moderately , [+ ] flomax, [no ] pxf, [no ] guttae, [+] 81 mg asa - discussed cataract surgery, patient elected to proceed with cataract surgery with iol left eye. with istent > risks, benefits, and alternatives to surgery were discussed with the patient, including but not limited to the potential risk of infection, bleeding, loss of vision, loss of eye, need for further surgery or laser, retinal detachment, change in glasses and reading glasses, macular edema, increased eye pressure and glaucoma. no guarantees given. all patient questions were answered.? > discussed available iols including presbyopia and astigmatism correcting lenses including all out-of-pocket expenses. could benefit from toric iol in os but since he has astigmatism in the LOCATION, he will still need glasses to correct the vision. he is fine with wearing glasses so we opted to not use a toric iol in the left eye. > pt opts for monofocal iol, aim distance ?> anesthesia: peribulbar block > other concerns: omidria/epishugarcaine asteroid hyalosis os - stable hx ocular htn, possible early poag os - iop excellent on latanoprost qhs os - tmax 27 ou - cct DATE_TIME DATE_TIME wnl ou DATE_TIME PERSON - hvf DATE_TIME borderline reliable od with central defects (difficult test due to fogging of the lens despite taping his mask) os nonspecific defects DATE_TIME nonspecific defects ou > observe refractive error > no significant change",
"gpt4_summary": "78-year-old patient with history of COPD, hypertension, and hyperlipidemia has visually significant cataract in left eye, affecting daily activities. Patient has agreed to proceed with cataract surgery and potential risks including infection, bleeding, vision loss, and glaucoma were discussed. Astigmatism and ocular hypertension noted, but eye pressure excellent on latanoprost. Early signs of primary open-angle glaucoma were also observed.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08253",
"image_path": "slo_fundus_08253.jpg",
"filename": "data_08253.npz",
"report": "The patient underwent laser iridotomy for narrow angles and shows signs of ocular cupping - a possible indicator of glaucoma. They have low intraocular pressure, cataracts, dermatochalasis, and pterygium.",
"age": 64.11,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "single",
"note": "imp: s/p laser iridotomy ou DATE_TIME for occludable narrow angles cupping ou; low iop, PERSON, nl hvf and oct amd ou - followed by dr. PERSON cataract ou dermatochalasis ou pterygium ou plan: DATE_TIME with hvf and oct rx=m rudnick pgy4 i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow. i have reviewed the resident/fellow's notes and made any necessary changes.",
"gpt4_summary": "The patient underwent laser iridotomy for narrow angles and shows signs of ocular cupping - a possible indicator of glaucoma. They have low intraocular pressure, cataracts, dermatochalasis, and pterygium.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08255",
"image_path": "slo_fundus_08255.jpg",
"filename": "data_08255.npz",
"report": "The patient has reduced acuity in the left eye and a cataract in the right eye, with no evidence of optic neuropathy. A macular hole has been noted by an ophthalmologist. No glaucoma present.",
"age": 79.04,
"gender": "male",
"race": "white",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "married or partnered",
"note": "prophylactic - a low dose beta blocker may be reasonable if he continues to have high blood pressure. he has reduced acuity in the left eye that has been stable over time. we did not find evidence of an optic neuropathy os and his evaluation of the neural components of his macula were normal. his outside ophthalmologist had noted a macular hole. he has bilateral dermatochalasis and a cataract od. these are not bothering him for now. recommendations: 1. could start a migraine prophylactic if he has frequent recurrence of positive visual phenomena 2. follow up with his comprehensive ophthalmologist i personally spent a total of *** DATE_TIME on care for this patient on the date of the encounter. this includes face-to-face time during the visit as well as non face-to-face time spent on chart documentation, and care coordination. this note was prepared by dr. PERSON, neuro-ophthalmology fellow, and me. any part of this note that was prepared by the resident or fellow was reviewed and modified as necessary by me to complete the finalized summary. ? PERSON, LOCATION.",
"gpt4_summary": "The patient has reduced acuity in the left eye and a cataract in the right eye, with no evidence of optic neuropathy. A macular hole has been noted by an ophthalmologist. No glaucoma present.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08257",
"image_path": "slo_fundus_08257.jpg",
"filename": "data_08257.npz",
"report": "63 y.o. black, non-hispanic female with no diagnosis of glaucoma.",
"age": 63.19,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "a 63 y.o. black, non-hispanic female with no diagnosis of glaucoma.",
"gpt4_summary": "63 y.o. black, non-hispanic female with no diagnosis of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08258",
"image_path": "slo_fundus_08258.jpg",
"filename": "data_08258.npz",
"report": "The clinical note discusses allergies, current medications, appointments, and overall health conditions of a patient. Notable medications include acetaminophen-codeine for pain and alendronate for osteoporosis. The patient is also taking levothyroxine for hypothyroidism. There is no mention of glaucoma.",
"age": 59.31,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "allergies as of DATE_TIME ibuprofen levofloxacin sulfa (sulfonamide antibiotics) sulfamethoxazole-trimethoprim medications and orders your current medications acetaminophen-codeine (tylenol-codeine #PHONE_NUMBER mg per tablet (taking) take 1-2 tablets by mouth every 4 (DATE_TIME as needed for pain (specific location in comments). alendronate (fosamax) 70 mg tablet (taking) take 1 tablet (70 mg total) by mouth DATE_TIME. PERSON (xanax) 0.25 mg tablet (taking) take 1 tablet (0.25 mg total) by mouth nightly as needed (back pain). cholecalciferol (vitamin d3) 2,000 unit capsule (taking) take by mouth DATE_TIME. conjugated estrogens (premarin) vaginal cream (taking) place 0.5 g vaginally nightly. use DATE_TIME x DATE_TIME then decrease to 2x/wk. levothyroxine (synthroid, levothroid) 75 mcg tablet (taking) take 1 tablet (75 mcg total) by mouth DATE_TIME. multivitamin per tablet (taking) take 1 tablet by mouth DATE_TIME. hrishikesh sawant DATE_TIME 2:26 am metal med transfer process pravastatin (pravachol) 20 mg tablet (taking) take 1 tablet (20 mg total) by mouth DATE_TIME. your orders future appointments provider department dept phone DATE_TIME PERSON alora LOCATION, PERSONtitution medical dermatology 617-726-2914 DATE_TIME alaka ray, PERSONtitution internal medicine associates 617-724-4600 DATE_TIME DATE_TIME PERSON, md, PERSON associates 617-742-2054 DATE_TIME 9:10 am PERSON, PERSONtitution comprehensive oph main campus PHONE_NUMBER orders placed this visit humphrey visual field - ou - both eyes oct, optic nerve - ou - both eyes - condition list as of DATE_TIME migraine dizziness back pain health care maintenance hypothyroidism osteoporosis results summary immunizations administered on date of encounter - DATE_TIME none",
"gpt4_summary": "The clinical note discusses allergies, current medications, appointments, and overall health conditions of a patient. Notable medications include acetaminophen-codeine for pain and alendronate for osteoporosis. The patient is also taking levothyroxine for hypothyroidism. There is no mention of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08259",
"image_path": "slo_fundus_08259.jpg",
"filename": "data_08259.npz",
"report": "The patient has primary open-angle glaucoma that's mild stage. Undergone glaucoma procedure, current IOP is acceptable. Also suffers from early cataract, refractive error (hyperopia, presbyopia), and dry eyes.",
"age": 72.11,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "1. primary open-angle glaucoma ou mild stage: tmax 18/25 mm hg; cct 480/475. angle narrow by PERSON but open on gonio DATE_TIME glaucoma procedure: od: slt DATE_TIME with PERSON: slt DATE_TIME with PERSON current iop is acceptable; tg < 16 od and =12 os 2. early cataract ou: minimally visually significant plan: observe 3. refractive error: hyperopia, presbyopia --continue current rx 4. dry eyes at prn plan iop excellent on cosopt bid visual field left eye is slowly worsening rnfl oct worse vs DATE_TIME gonioscopy remains open goal now near 12 os - continue ltn and timolol bid both eyes - rtc DATE_TIME iop check",
"gpt4_summary": "The patient has primary open-angle glaucoma that's mild stage. Undergone glaucoma procedure, current IOP is acceptable. Also suffers from early cataract, refractive error (hyperopia, presbyopia), and dry eyes.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08263",
"image_path": "slo_fundus_08263.jpg",
"filename": "data_08263.npz",
"report": "53-year-old female is a glaucoma suspect due to cup:disc appearance, likely physiologic in healthy appearing rims; low intraocular pressure. No family history of glaucoma.",
"age": 53.31,
"gender": "female",
"race": "white",
"ethnicity": "unknown",
"language": "spanish",
"maritalstatus": "married or partnered",
"note": "53 y.o. female healthy here with husband in past; here alone DATE_TIME - glaucoma suspect based on cup:disc appearance ou, likely physiologic in setting of healthy appearing rims and low iop fam hx: none tmax: 15/15 cct thin: 498/498 gonio : hvf DATE_TIME: ou full DATE_TIME: ou full rnfl DATE_TIME: ou wnl DATE_TIME: PERSON and stable, PERSON with slightly decreased avg nfl disc photos: DATE_TIME last dilated: DATE_TIME >> monitor off eyedrops given normal testing DATE_TIME - refractive error >> defers new glasses prescription DATE_TIME. she asked about possibility of surgery to eliminate need for glasses. we discussed laser vision correction but possibility of needing reading glasses if target distance, or blended/minimonovision. also discussed contact lenses. she will continue with glasses for now f/up DATE_TIME with hvf, rnfl oct, dilation, sooner prn",
"gpt4_summary": "53-year-old female is a glaucoma suspect due to cup:disc appearance, likely physiologic in healthy appearing rims; low intraocular pressure. No family history of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08265",
"image_path": "slo_fundus_08265.jpg",
"filename": "data_08265.npz",
"report": "Patient has optic nerve hypoplasia, mild refractive error os>od, 1 pd right hypertropia, inferior field loss in both eyes, anxiety and nausea. No glaucoma indication.",
"age": 49.19,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "formulation: this patient returns for follow up of optic nerve hypoplasia and intermittent, achy left eye pain that precipitates anxiety and nausea. her exam is notable for mild refractive error os>od. her anterior exam is normal. her optic nerves appear hypoplastic and her humphrey visual fields are notable for inferior field loss in both eyes. her efferent exam is notable for a 1 pd right hypertropia at distance. it seems that he symptoms may be related to both refractive error and a small vertical misalignment. assessment: 1. hypoplastic optic nerves, possibly secondary to superior segmental optic nerve atrophy 2. refractive error 3. small right hypertropia 4. history of PERSON ou plan: 1. we will plan to bring the patient back for prism measurements (undilated) and refraction in DATE_TIME and provide a new prescription at that time this patient was seen and note prepared with PERSON, ophthalmology resident.",
"gpt4_summary": "Patient has optic nerve hypoplasia, mild refractive error os>od, 1 pd right hypertropia, inferior field loss in both eyes, anxiety and nausea. No glaucoma indication.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08266",
"image_path": "slo_fundus_08266.jpg",
"filename": "data_08266.npz",
"report": "The patient has vision problems and is suspected of having narrow angle glaucoma in both eyes, shown by their specialty eye tests. They also have a mild cataract but no current treatments or medications.",
"age": 67.14,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "problem list items addressed this visit eye/vision problems narrow angle glaucoma suspect of both eyes overview primary angle closure suspect. target iop: / ; tmax: ( ) / ( ); central corneal thickness: / ; ch: / refractive error: od +3.25 . sphere x / os +2.50 . sphere x optic nerve structure and function: normal visual field and retinal nerve fiber layer at presentation (DATE_TIME). medications and intolerances: none procedures and complications: none relevant history and problems: cataract - mild current assessment & plan no intraocular pressure treatment now. rx specs. other visit diagnoses narrow angle glaucoma suspect relevant orders humphrey visual field - ou - both eyes (completed) oct, optic nerve - ou - both eyes - (completed) return in DATE_TIME (around DATE_TIME) for optic nerve imaging (oct), visual field, gonioscopy, pachymetry.",
"gpt4_summary": "The patient has vision problems and is suspected of having narrow angle glaucoma in both eyes, shown by their specialty eye tests. They also have a mild cataract but no current treatments or medications.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08270",
"image_path": "slo_fundus_08270.jpg",
"filename": "data_08270.npz",
"report": "The patient's right eye is consistently over the goal. BGI was performed with three fenestrations. Considerations include phaco/BGI for the left eye and Rhopressa QHS if IOP exceeds 12 mmHg. Glaucoma may be present.",
"age": 72.03,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "persistently above goal od on PERSON except for PERSON, we proceeded with bgi od st (3 fenestrations) in the sulcus on DATE_TIME. -rtc in DATE_TIME with iop check and oct rnfl/gcc ou, sooner prn. if good result obtained od, we may want to consider phaco/bgi os. if iop above 12 mmhg od, we will also consider rhopressa qhs or LOCATION to head off hypertensive phase. the information above was documented by Person as a scribe for PERSON on DATE_TIME.",
"gpt4_summary": "The patient's right eye is consistently over the goal. BGI was performed with three fenestrations. Considerations include phaco/BGI for the left eye and Rhopressa QHS if IOP exceeds 12 mmHg. Glaucoma may be present.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08272",
"image_path": "slo_fundus_08272.jpg",
"filename": "data_08272.npz",
"report": "Patient has chronic angle-closure glaucoma in right eye and ocular hypertension in left. Pressure is controlled and stable. Has pseudophakia which is stable and previous retinal detachments but is stable.\n",
"age": 52.21,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "1. chronic angle-closure glacuoma od / ocular hypertension os: cct 630/570 iop goal less than 21mmhg. iop control is well within the target range. ran out of brimonidine and travatan DATE_TIME; pressure remains stable. plan: cont cosopt ou bid hold brimonidine 0.15% ou bid for now hold travatan ou qhs for now f/u DATE_TIME pressure check 2. pseudophakia (pciol) ou: stable plan: observe DATE_TIME/o multiple retinal detachments od s/p sb: stable plan: rd precautions discussed monocular precautions",
"gpt4_summary": "Patient has chronic angle-closure glaucoma in right eye and ocular hypertension in left. Pressure is controlled and stable. Has pseudophakia which is stable and previous retinal detachments but is stable.\n",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08277",
"image_path": "slo_fundus_08277.jpg",
"filename": "data_08277.npz",
"report": "The clinical note does not indicate the presence of glaucoma. It mentions color fundus photography, visual field for both eyes, and retina examinations. The patient has multiple conditions like back pain, depression, osteoporosis, among others.",
"age": 55.09,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "vishal mane DATE_TIME needs PERSON. metal med transfer process. ropinirole (requip) 1 mg tablet 3 mg tab p.o. DATE_TIME your orders normal orders this visit color fundus photography - ou - both eyes PERSON visual field - ou - both eyes oct, retina - ou - both eyes - cirrus; retina; 6mm length; 0.25mm spacing future labs/procedures complete by expires mri angio neck DATE_TIME DATE_TIME mri brain DATE_TIME DATE_TIME oct, retina - ou - both eyes - cirrus; retina; 6mm length; 0.25mm spacing as directed DATE_TIME condition list as of DATE_TIME back pain depression osteoporosis injury of head endometriosis restless leg syndrome migraine hearing loss sleep apnea asthma hypertensive disorder ddd (degenerative disc disease), lumbar lumbar spondylosis thoracic spondylosis sciatica traumatic brain injury hyperlipidemia age-related nuclear cataract of both eyes facet joint disease neuropathic pain results summary immunizations administered on date of encounter - DATE_TIME none",
"gpt4_summary": "The clinical note does not indicate the presence of glaucoma. It mentions color fundus photography, visual field for both eyes, and retina examinations. The patient has multiple conditions like back pain, depression, osteoporosis, among others.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08280",
"image_path": "slo_fundus_08280.jpg",
"filename": "data_08280.npz",
"report": "Patient has myopic astigmatism, presbyopia, and is deemed a glaucoma suspect with ocular pressure of 24 mmHg. Recommended glaucoma-related tests.",
"age": 49.32,
"gender": "female",
"race": "white",
"ethnicity": "unknown",
"language": "unknown",
"maritalstatus": "married or partnered",
"note": "1. myopic astigmat against the rule, presbyope 2. rx = -0.25-0.75x135 add +1.75 -0.50 -0.50x90 add +1.75 3. glaucoma suspect based on iop's of 24 mmhg ou............. refer to glaucoma for vf and onh photos 4. confrontational visual fields seems slightly constricted.",
"gpt4_summary": "Patient has myopic astigmatism, presbyopia, and is deemed a glaucoma suspect with ocular pressure of 24 mmHg. Recommended glaucoma-related tests.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08283",
"image_path": "slo_fundus_08283.jpg",
"filename": "data_08283.npz",
"report": "The patient has mog-associated disease/optic neuritis. Their care team is working on insurance approval for IVIG treatment. No mention of glaucoma.",
"age": 69.06,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "flares. PERSON has the best data for reduction of DATE_TIME relapse rate of mog-associated disease/optic neuritis, and arguably a better side-effect profile than rituximab or cellcept. i agree with the recommendation of DATE_TIME ivig under the care of dr. PERSON whose team has been working for insurance approval. ? i will plan to see her back in DATE_TIME to monitor her progress. recommendations: 1. agree with DATE_TIME ivig treatments 2. return to see me in DATE_TIME i personally spent a total of DATE_TIME on care for this patient on the date of the encounter. this includes face-to-face time during the visit as well as non face-to-face time spent on chart documentation, and care coordination. ? PERSON, LOCATION.",
"gpt4_summary": "The patient has mog-associated disease/optic neuritis. Their care team is working on insurance approval for IVIG treatment. No mention of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08285",
"image_path": "slo_fundus_08285.jpg",
"filename": "data_08285.npz",
"report": "The patient, a 56 y.o. female, is a glaucoma suspect due to the cup to disc ratio in both eyes. There's no thinning of the retinal fiber layer or reduction in visual fields. No treatment commenced, will continue monitoring. She also has mild cataracts.\n",
"age": 56.9,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "hysteresis: 9.6 / 8.6 gonioscopy: d30f 2+ ou retinal nerve fiber layer, right eye: no thinning retinal nerve fiber layer, left eye: no thinning visual fields, right eye: full visual fields, left eye: full family history: none steroids: none trauma: none asthma/copd: none other medical history and problems: htn, hld, nafld, migraine, anxiety, depression assessment/plan: 56 y.o. female nwh medical assistant referred by dr. PERSON ding # glaucoma suspect due to cup to disc ratio, both eyes, both eyes - healthy nerve rim, reassuring testing - iop acceptable ou - continue to monitor without initiating treatment - return in DATE_TIME for iop check, dilate, oct, disc photos # cataract, both eyes - mild, not visually significant, monitor PERSON, PERSON___________________ i saw and evaluated this patient and discussed the case as appropriate with the fellow. i have reviewed the fellow's notes and made any necessary changes. PERSON scribing for dr. PERSON i attest that i was present while this encounter was recorded and agree that the information entered by my scribe and updated by me is complete and accurate. PERSON, md",
"gpt4_summary": "The patient, a 56 y.o. female, is a glaucoma suspect due to the cup to disc ratio in both eyes. There's no thinning of the retinal fiber layer or reduction in visual fields. No treatment commenced, will continue monitoring. She also has mild cataracts.\n",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08287",
"image_path": "slo_fundus_08287.jpg",
"filename": "data_08287.npz",
"report": "The patient is on several medications including venlafaxine, docusate sodium, neurontin, melatonin, omeprazole and vitamin B complex. No presence of glaucoma reported. Other conditions include asthma, depression, osteoarthritis, and urinary tract infection.",
"age": 76.56,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "venlafaxine (PERSON) 75 mg tablet (taking) take 1 tablet by mouth twice a day custom medication, see admin inst / label comment, reported on DATE_TIME DATE_TIME needs PERSON. metal med transfer process, from oncall docusate sodium (colace) 100 mg capsule take 1 capsule (100 mg total) by mouth 2 (two) times a day as needed for constipation. PERSON (neurontin) 300 mg capsule take 1 capsule (300 mg total) by mouth nightly as needed. melatonin 5 mg tab take 1 tablet (5 mg total) by mouth nightly. omeprazole (prilosec) 20 mg capsule take 20 mg by mouth DATE_TIME. reported on DATE_TIME DATE_TIME 3:23 am metal med transfer process, from PERSON (LOCATION) 20 mg tablet take 1 tablet (20 mg total) by mouth DATE_TIME. vitamin b complex oral take by mouth. reported on DATE_TIME DATE_TIME 3:27 am needs PERSON. metal med transfer process, from oncall your orders normal orders this visit humphrey visual field - ou - both eyes oct, optic nerve - ou - both eyes - condition list as of DATE_TIME asthma allergic rhinitis rectal prolapse depressive disorder atypical chest pain hypercholesterolemia s/p cholecystectomy history of bladder suspension procedure h/o hysterectomy for benign disease obesity fatigue osteoarthritis abnormal results of liver function studies gastroesophageal reflux disease seborrheic keratosis seborrheic dermatitis contact dermatitis actinic keratosis lumbar stenosis urinary incontinence urinary tract infection, site not specified chronic headaches routine adult health maintenance right hip pain results summary immunizations administered on date of encounter - DATE_TIME none",
"gpt4_summary": "The patient is on several medications including venlafaxine, docusate sodium, neurontin, melatonin, omeprazole and vitamin B complex. No presence of glaucoma reported. Other conditions include asthma, depression, osteoarthritis, and urinary tract infection.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08300",
"image_path": "slo_fundus_08300.jpg",
"filename": "data_08300.npz",
"report": "The patient is prescribed preservative-free artificial tears and will follow-up for cornea care. A check-up for intraocular pressure (IOP) is scheduled, with the possibility of Selective Laser Trabeculoplasty (SLT) treatment for glaucoma.",
"age": 59.13,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "to medication regimen. -instructions written/typed/printed out for patient (see table/details under patient instructions) previously. -preservative-free artificial tears as needed. -follow-up with dr. PERSON for cornea care. -rtc in DATE_TIME with iop check and hvf size v ou, sooner prn. if iop above goal or difficulty with adherence, we'll book slt os first, and if good result od. the information above was documented by PERSON as a scribe for PERSON on DATE_TIME.",
"gpt4_summary": "The patient is prescribed preservative-free artificial tears and will follow-up for cornea care. A check-up for intraocular pressure (IOP) is scheduled, with the possibility of Selective Laser Trabeculoplasty (SLT) treatment for glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08304",
"image_path": "slo_fundus_08304.jpg",
"filename": "data_08304.npz",
"report": "The patient has open-angle glaucoma, mild stage, with high intraocular pressure. Started on latanoprost. Underwent SLT with good response. Plan is to continue medication and follow-up.",
"age": 23.16,
"gender": "female",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "visual acuity visual acuity (snellen - linear) right left dist cc PHONE_NUMBER correction: glasses tonometry tonometry (applanation, DATE_TIME) right left pressure 17 15 main ophthalmology exam external exam right left external normal normal slit lamp exam right left lids/lashes normal normal conjunctiva/sclera normal normal cornea normal normal anterior chamber normal normal iris normal normal lens normal normal fundus exam right left vitreous normal normal disc normal normal c/d ratio 0.9 0.9 macula normal normal vessels normal normal periphery normal normal problem list items addressed this visit eye/vision problems open-angle glaucoma, mild stage overview early juvenile open-angle glaucoma ou: cct 660/660 tm 23/24: +family history. pt's iop has been high in previous visits and rfnl was showing some changes. pt has a possible vf defect os, but that is not significantly different than DATE_TIME. started on latanoprost by PERSON PERSON. iop higher DATE_TIME. will initially set goal at teens ou for ~20% decr in tm. stable vf with some fluctuation in vf os with early sup defects that don't appear worse since DATE_TIME. oct with no signficant change but may have slightly more sup thinning od --> will repeat with dilated test to confirm. testing stable but with high iop again so slt DATE_TIME with good response goal <18 current assessment & plan iop continues to be good after slt os DATE_TIME (20s --> mid teens) plan: latanoprost ou qhs follow-up in DATE_TIME iop check PERSON, LOCATION",
"gpt4_summary": "The patient has open-angle glaucoma, mild stage, with high intraocular pressure. Started on latanoprost. Underwent SLT with good response. Plan is to continue medication and follow-up.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08318",
"image_path": "slo_fundus_08318.jpg",
"filename": "data_08318.npz",
"report": "No evidence of glaucoma or sub-clinical abnormalities found. Patient has blurred vision, occipital neuralgia, and history of optic nerve 'pit'. Recommended trigger point injection.",
"age": 38.93,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "superiorly, i did not find any evidence of neural damage to account for her report of reduced vision. i also obtained fundus autofluorescence which did not show any sub-clinical abnormalities. i then obtained corneal topography, which performed with respect to the head pain, i suspect that she has occipital neuralgia. notably, the pain definitely does not include the cervical muscles. given the degree to which she is symptomatic, i suggested that she consider a trigger point injection, which she wishes to pursue.. she has carried a diagnosis of 'optic nerve pit' on the left. there is clearly a round, focal defect adjacent to the optic nerve head, but the high quality optical coherence tomography confirms both that the lesion lies outside of the nerve and that the ganglion cell complex is not diminished, as occurs with a pit. as such, this defect, which is in the collagen adjacent to the scleral ring, is not truly an optic nerve pit. diagnoses. 1. blurred vision, progressive, od, without evidence of neural or obvious optical explanation 2. significant head pain in region of occipital notch, with point tenderness, right, secondary to occipital neuralgia 3. history of optic nerve 'pit', os, but defect is outside of the nerve proper recommendations. 1. return for repeat measurement of central acuity od 2. trigger point injection at return appointment PERSON, PERSON, neuro-ophthalmology service i spent a total of DATE_TIME personally preparing and caring for this patient (face-to-face and non face-to-face); formulating, obtaining a series of imaging studies and review of each; reaching out to two corneal faculty members to return the pentacam images, reviewing my findings and discussing a management plan with the patient including the trigger point injection, and finalizing the note.]",
"gpt4_summary": "No evidence of glaucoma or sub-clinical abnormalities found. Patient has blurred vision, occipital neuralgia, and history of optic nerve 'pit'. Recommended trigger point injection.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08329",
"image_path": "slo_fundus_08329.jpg",
"filename": "data_08329.npz",
"report": "Patient has mild cataract and nevus in right eye, dry and refractive error in both eyes, and ocular hypertension in left eye. Suspected glaucoma is more in left eye than right.",
"age": 58.33,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "imp: pciol os mild cataract od ch nevus od dry ou refr error hx ocular htn os. glaucoma suspect os > od. PERSON open ou prev cct 570/565 tmax 19/29 hvf full and oct rnfl with thinning od > os stable plan: cont xalatan ou qhs ats ou qid rx=m 6 PERSON",
"gpt4_summary": "Patient has mild cataract and nevus in right eye, dry and refractive error in both eyes, and ocular hypertension in left eye. Suspected glaucoma is more in left eye than right.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08331",
"image_path": "slo_fundus_08331.jpg",
"filename": "data_08331.npz",
"report": "The patient is diagnosed with atypical idiopathic intracranial hypertension, with prominent radial retinal folds. No glaucoma is reported.",
"age": 46.48,
"gender": "male",
"race": "white",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "married or partnered",
"note": "periodically, and should return for new or worsening symptoms. diagnoses. 1. atypical idiopathic intracranial hypertension, with prominent radial retinal folds in a man in his DATE_TIME without weight gain or medication use. recommendations. 1. continue off diamox 2. rtc as needed 3. comprehensive for DATE_TIME eye exams 1. continue off diamox 2. rtc DATE_TIME or sooner for new symptoms PERSON, PERSON, neuro-ophthalmology service (this note was prepared with the assistance of dr. PERSON.) ----- i spent a total of DATE_TIME preparing and caring for this patient (face-to-face and non face-to-face); formulating (including review of the presentation with the resident or review of medical tests) and finalizing the note.]",
"gpt4_summary": "The patient is diagnosed with atypical idiopathic intracranial hypertension, with prominent radial retinal folds. No glaucoma is reported.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08333",
"image_path": "slo_fundus_08333.jpg",
"filename": "data_08333.npz",
"report": "The patient has cornea care with checks for intraocular pressure (IOP), field of vision (HVF), and retinal nerve fiber layer (RNFL). If IOP is elevated, medications (brimonidine or timolol) could be used. No mention of glaucoma.",
"age": 72.77,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "NAME for cornea care. -rtc in DATE_TIME with iop check ou, hvf, dilation, and oct rnfl/gcc ou, sooner prn. low threshold to start brimonidine or timolol od if iop persistently above goal. the information above was documented by PERSON as a scribe for PERSON on DATE_TIME.",
"gpt4_summary": "The patient has cornea care with checks for intraocular pressure (IOP), field of vision (HVF), and retinal nerve fiber layer (RNFL). If IOP is elevated, medications (brimonidine or timolol) could be used. No mention of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08334",
"image_path": "slo_fundus_08334.jpg",
"filename": "data_08334.npz",
"report": "Patient exhibits afferent pupillary defect, metamorphopsia & has defects in visual fields. Has a history of sequential naion and erosion of epiretinal membrane. No evidence of progression of optic neuropathy or glaucoma present.",
"age": 71.71,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "afferent pupillary defect on the left. there is significant metamorphopsia in the left eye on amsler grid. automated visual fields done with good test performance show dense inferior altitudinal defects ou with a superior nasal defect os. these defects appear stable when compared to the last available vf from DATE_TIME. extraocular motility is full and the patient is orthophoric in all gaze directions. on dilated fundus evaluation, there is pallor of both optic nerve heads os > od and there is an erm os; oct of the macula confirms the presence of an erm with significant architectural distortion. in summary, PERSON has a history of sequential naion (od 2011, os DATE_TIME) for which she was followed at Institution until DATE_TIME. her most recent decline in vision in the left eye is most likely explained by progression of an epiretinal membrane; i do not have access to prior oct of the macula to confirm this hypothesis, but based on the prior neuro-ophthalmology records from DATE_TIME (cf visual fields), there is no evidence of progression of the optic neuropathy on either side. in this context, i suggested PERSON to be evaluated by retina to consider a surgical correction of the erm. i will see her again in DATE_TIME, before if needed. ? impression: 1. sequential naion -od DATE_TIME. erm os -visually significant. recommendations: 1. referral to retina 2. continue follow up with ophthalmology 3. return to neuro-ophthalmology in DATE_TIME, before if needed. it is a pleasure to participate in the care of this patient. please do not hesitate to call with questions.",
"gpt4_summary": "Patient exhibits afferent pupillary defect, metamorphopsia & has defects in visual fields. Has a history of sequential naion and erosion of epiretinal membrane. No evidence of progression of optic neuropathy or glaucoma present.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08335",
"image_path": "slo_fundus_08335.jpg",
"filename": "data_08335.npz",
"report": "Clinical note implies a high threat to patient's vision/neurological function/systemic health. High risk of morbidity related to diagnosis. No mention of glaucoma.",
"age": 52.06,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "problems as detailed under 'diagnoses' above that pose a threat to vision / neurological function or systemic health. my assessment of this case also included review of the following data: including: results of tests and documents from our er, review of unique test results (including those described under 'ancillary studies' above and review of the mri), ordering unique tests) with respect to management, this patient has a potential high risk of morbidity related to his diagnosis.]",
"gpt4_summary": "Clinical note implies a high threat to patient's vision/neurological function/systemic health. High risk of morbidity related to diagnosis. No mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08338",
"image_path": "slo_fundus_08338.jpg",
"filename": "data_08338.npz",
"report": "47 y.o. white, non-hispanic female. No diagnosis of glaucoma. Information recorded accurately by scribe.",
"age": 47.57,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "a 47 y.o. white, non-hispanic female with no diagnosis of glaucoma. present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "47 y.o. white, non-hispanic female. No diagnosis of glaucoma. Information recorded accurately by scribe.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08346",
"image_path": "slo_fundus_08346.jpg",
"filename": "data_08346.npz",
"report": "The patient presented with blurry vision due to uncorrected refractive error and exophoria at near. Examination revealed optic disc edema, secondary to meningioma resection. No mentions of glaucoma.",
"age": 11.77,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "formulation: this patient presents for evaluation of blurry vision in setting of atypical meningioma with extension to sagittal sinus and skull. DATE_TIME's exam showed decreased visual acuity in each eye which improves to normal with pin-hole, indicating uncorrected refractive error. his afferent exam was normal with full color plates and excellent stereopsis. ocular motilities were full with a moderate exophoria at near. visual field testing was normal although there were excessive false positives in the right eye. OCT RNFL confirms the presence of edema in both eyes. oct gcc segmentation analysis shows early thinning of the gcc in both eyes. fundus exam showed mild swelling of both optic nerves. given this patient's diagnosis and the fact that he is currently going through radiation therapy, i would like to follow him closely with repeat exam and hvf in DATE_TIME. his blurry vision is refractive but i recommend holding off on finalizing a glasses prescription until his condition has stabilized. impression: 1. optic disc edema ou, secondary to #2 2. meningioma s/p resection, h/o hydrocephalus, now with vp shunt 3. refractive error 4. Exophoria at near, asymptomatic recommendations: 1-2. follow-up neuro-ophthalmology clinic DATE_TIME with hvf 3-4. discussed nature of near-sightedness with patient and mother. refer to optom (here or children's) for refraction once findings stabilize this note was prepared with the assistance of haley italia, od, resident",
"gpt4_summary": "The patient presented with blurry vision due to uncorrected refractive error and exophoria at near. Examination revealed optic disc edema, secondary to meningioma resection. No mentions of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08347",
"image_path": "slo_fundus_08347.jpg",
"filename": "data_08347.npz",
"report": "The clinical note does not provide specific details about the presence of glaucoma. Important information included the central corneal thickness (496 / 498) and refractive error for both eyes. The patient has a history of left-sided stroke, dementia, and right sided weakness.",
"age": 73.11,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "first seen by Person on DATE_TIME diagnosis: *** target iop: / , tmax: ( ) / ( ) central corneal thickness: 496 / 498 gonioscopy: *** refractive error: OD +0.50 . -1.00 . 178 / os +0.50 . -1.75 . 178 optic nerve/rnfl findings on baseline visit right eye (DATE_TIME): *** optic nerve/rnfl findings on baseline visit left eye (DATE_TIME): *** visual fields on baseline visit right eye (DATE_TIME): *** visual fields on baseline visit left eye (DATE_TIME): *** medication history at first visit: medication intolerances: glaucoma procedures right eye: glaucoma procedures left eye: other eye procedures right eye: other eye procedures left eye: other eye problems right eye: other eye problems left eye: family history: steroids: trauma: asthma: other medical history and problems: assessment: 1. *** - 2. *** - plan: -cpm rtc DATE_TIME for dfe dementia left sided stroke with right sided ue weakness and a right hemianopsia",
"gpt4_summary": "The clinical note does not provide specific details about the presence of glaucoma. Important information included the central corneal thickness (496 / 498) and refractive error for both eyes. The patient has a history of left-sided stroke, dementia, and right sided weakness.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08352",
"image_path": "slo_fundus_08352.jpg",
"filename": "data_08352.npz",
"report": "The 58-year-old patient, a registered nurse, presents with ocular hypertension, no genetic history of glaucoma, but shows few symptoms like enlarged blind spots and rim losses. Prescription given to control intraocular pressure.",
"age": 58.96,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "58 yo rn working in home care with history of hypercholesterolemia, asthma, anemia, recent vertigo attributed to viral PERSON\u00ff 1. ocular hypertension tmax 23/24. cct DATE_TIME (thin). no fhx hvf DATE_TIME: od enlarged bs, few inferior losses. os sn rim losses hvf DATE_TIME: full ou hvf DATE_TIME: PERSON reliability, full. os better reliability, isolated sn loss, prob full. hvf DATE_TIME: full ou hvf DATE_TIME: PERSON. os ?PERSON, trace ins DATE_TIME: PERSON ou (os inferior rim slightly thinner than prior-- 114 from 122) DATE_TIME: wnl ou oct DATE_TIME: wnl ou, stable DATE_TIME: wnl ou, stable DATE_TIME: wnl ou oct DATE_TIME: od borderline superior thinning. os PERSON DATE_TIME: trace PERSON, os superior and inferior thinning iop DATE_TIME: 13/13 mmhg -continue xalatan ou qhs (dense sa when off xalatan for DATE_TIME in past) >> use at prior to xalatan for recent burning after instillation (worse if using DATE_TIME) - refill sent DATE_TIME dp DATE_TIME: od only (0.5) >> will continue to follow on xalatan, watch inferior rim os. repeat hvf and oct on f/u \u00ff 2. rpe changes od -stable \u00ff 3. mild cataract ou -follow \u00ff 4. dry eyes ou - symptomatic with extended computer use >> continue artificial tears prn PERSON, pgy-4 i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow. i have reviewed the resident/fellow's notes and made any necessary changes. \u00ff",
"gpt4_summary": "The 58-year-old patient, a registered nurse, presents with ocular hypertension, no genetic history of glaucoma, but shows few symptoms like enlarged blind spots and rim losses. Prescription given to control intraocular pressure.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08359",
"image_path": "slo_fundus_08359.jpg",
"filename": "data_08359.npz",
"report": "The patient has moderate to severe primary open angle glaucoma in both eyes, more so in the right one. They've had previous treatment and have no family history of glaucoma. The patient also has dry age-related macular degeneration and allergies to medication including Alphagan. Historical conditions include basal cell cancer. They have history of heart failure, hypertension, and take aspirin.",
"age": 84.03,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "?# moderate to severe primary open angle glaucoma od > os - pachymetry (530/546); tmax 22/27 (on treatment per old records from dr. PERSON); no fhx of glaucoma - followed previously by dr. PERSON in LOCATION, ma - s/p alt ou (od x 5 most recent in DATE_TIME; os x 1 in DATE_TIME) - s/p slt od (DATE_TIME) - hvf with LOCATION PERSON; sns os - oct-rnfl (51/76) with sup and PERSON <= 12 ou; borderline od DATE_TIME ? - cosopt bid ou - travatan qhs ou # dry amd ou - areds ii # toric pciol ou (DATE_TIME) - follow # h/o rll basal cell ca s/p mohs and reconstruction (DATE_TIME) - per dr. PERSON or dr. PERSON ? social/systemic: alphagan allergy; h/o chf and LOCATION; htn; asa 81 ? rtc DATE_TIME with hvf ou",
"gpt4_summary": "The patient has moderate to severe primary open angle glaucoma in both eyes, more so in the right one. They've had previous treatment and have no family history of glaucoma. The patient also has dry age-related macular degeneration and allergies to medication including Alphagan. Historical conditions include basal cell cancer. They have history of heart failure, hypertension, and take aspirin.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08360",
"image_path": "slo_fundus_08360.jpg",
"filename": "data_08360.npz",
"report": "The 66-year-old woman is a previous patient with vitreous floaters, a history of EKC, inferior scleral show and cataracts in both eyes. She has suspected glaucoma in her left eye due to C:D asymmetry, family history (mother) and IOP of 15/16 Pachy 575/569. She also has a history of ocular migraines.",
"age": 66.16,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "66 y.o. woman \u00ff Former patient of Dr. PERSON \u00ff 1. Vitreous floaters OU -Patient with PVD OU -No retinal hole/tear/detachment on DFE OU today RD precautions reviewed 2. History of EKC OU -Patient with history of EKC in 2008 -Patient with multiple recurrences of subepithelial infiltrates with taper of steroids -Patient with recurrent subepithelial infiltrates OD in 3/2018 \u00ff Previously discussed with patient that her subepithelial infiltrates OD may be related to HSV (given her history of cold sores and frequency of recurrence OD) \u00ff -No subepithelial infiltrates OD since stopping lotemax \u00ff 3. Inferior scleral show OU DES/MGD OU -Likely contributing to her report of eye burning and irritation OU \u00ff Patient had not noticed any benefit from Xiidra (given possibility that Xiidra can increase risk of HSV recurrence, recommended stopping Xiidra) \u00ff Continue Refresh PM/Genteal PM/Systane PM 1 application nightly both eyes Continue Theratears 1 drop four times daily both eyes Continue off of Xiidra now \u00ff 4. Cataracts OU -Becoming visually significant, but patient denies problematic symptoms currently \u00ff 5. PVD OU -RD precautions reviewed \u00ff 6. Glaucoma suspect OS -Given C:D asymmetry OS>OD -Patient with family history of glaucoma (mother) -IOP 15/16 Pachy 575/569: true IOP same as measured OCT RNFL 5/19/2021: normal OU HVF 5/19/2021: full OU \u00ff 7. Ocular migraine -Patient with history of ocular migraine previously -Monitor \u00ff",
"gpt4_summary": "The 66-year-old woman is a previous patient with vitreous floaters, a history of EKC, inferior scleral show and cataracts in both eyes. She has suspected glaucoma in her left eye due to C:D asymmetry, family history (mother) and IOP of 15/16 Pachy 575/569. She also has a history of ocular migraines.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08361",
"image_path": "slo_fundus_08361.jpg",
"filename": "data_08361.npz",
"report": "The patient has primary open angle glaucoma, with good pressures and stable visual fields. They're prescribed xalatan. Their macular edema has resolved. No diabetic eye disease noted and they're advised to control glycemic levels.",
"age": 83.44,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "last seen by me DATE_TIME. 1. primary open angle glaucoma ou: pressures DATE_TIME are good on xalatan ou qhs; visual fields DATE_TIME show stable nasal step od. optical coherence tomography show stable thinning od inferiorly. - cont latanoprost ou qhs - return pressure check and dilation in DATE_TIME dfe: 11/21 hvf: 6/22 oct: 6/22 gonio: 3/13 tmax: 22/17 cct: 502, 509 fhx: yes 2. pseudophakia ou: h/o PERSON macular edema od, now resolved - stable 3. niddm: no eye disease; not on medications now - encourage glycemic control 4. refractive: stable - keep old glasses",
"gpt4_summary": "The patient has primary open angle glaucoma, with good pressures and stable visual fields. They're prescribed xalatan. Their macular edema has resolved. No diabetic eye disease noted and they're advised to control glycemic levels.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08371",
"image_path": "slo_fundus_08371.jpg",
"filename": "data_08371.npz",
"report": "93 y.o. white, non-Hispanic male diagnosed with glaucoma. Follow-up as needed.",
"age": 93.04,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "a 93 y.o. white, non-hispanic male was evaluated and diagnosed with glaucoma. continue at prn",
"gpt4_summary": "93 y.o. white, non-Hispanic male diagnosed with glaucoma. Follow-up as needed.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08373",
"image_path": "slo_fundus_08373.jpg",
"filename": "data_08373.npz",
"report": "The patient has hyperopia, astigmatism, presbyopia, and dryness in eyes. He reports some dizziness and decreasing flashes of lights. Examination reveals no evidence of pigmented cells, retinal tears, etc. He's a low suspicion glaucoma suspect.\n",
"age": 65.53,
"gender": "male",
"race": "white",
"ethnicity": "hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "PERSON is a DATE_TIME. male hyperopia w/ astigmatism and presbyopia ou optional rx given per pt's request pt denies changes to vision, wears pals which he has for DATE_TIME. pt reports that he's tilting head back on while using computer to see better. obstructive sleep apnea pt reports dryness in ou does not use any gtts. he does not have humidifier at home but there is one on his cpap. he reports some dizziness but may be due to his ear, on medication\u00fffor htn pvd os synereses od warned of rd sx's rtc for new floaters, flashes, or curtains pt reports that flashes of lights have been decreasing since PERSON reports that floaters in os seem stable, he has had them before pvd and they look the same pt denies pain ou -- he felt pressure when he was at the ed, but now resolved. per ed visit (dr. PERSON on DATE_TIME): ------------------------------------------------------------- there is no evidence of pigmented cells in anterior vitreous, no retinal tears, breaks, holes, or detachment on dilated fundus exam with scleral depression ------------------------------------------------------------- cornea scratched os DATE_TIME low suspicion glaucoma suspect risks include: c/d asym PERSON 0 od -1 os hvf 24-2 wnl ou oct wnl ou ofhx: mother and sister with cataracts aunt with armd ou f/u in DATE_TIME for dfe, ar/refract",
"gpt4_summary": "The patient has hyperopia, astigmatism, presbyopia, and dryness in eyes. He reports some dizziness and decreasing flashes of lights. Examination reveals no evidence of pigmented cells, retinal tears, etc. He's a low suspicion glaucoma suspect.\n",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08378",
"image_path": "slo_fundus_08378.jpg",
"filename": "data_08378.npz",
"report": "81-year-old white, non-hispanic male diagnosed with glaucoma. His account is activated and ready for use.",
"age": 81.57,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "a 81 y.o. white, non-hispanic male was evaluated and diagnosed with glaucoma. activation information your account is ready to use. LOCATION.",
"gpt4_summary": "81-year-old white, non-hispanic male diagnosed with glaucoma. His account is activated and ready for use.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08381",
"image_path": "slo_fundus_08381.jpg",
"filename": "data_08381.npz",
"report": "The note mentions further worsening of inferior. It also suggests the need for an intraocular pressure (IOP) check, a Humphrey visual field (HVF) test for the left eye, and disc photos. No mention of glaucoma.",
"age": 76.7,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "worsening of inferior PERSON with PERSON PERSON over the phone on DATE_TIME. -rtc in DATE_TIME with iop check ou, hvf os (with coaching), and disc photos ou, sooner prn. the information above was documented by PERSON as a scribe for PERSON on DATE_TIME.",
"gpt4_summary": "The note mentions further worsening of inferior. It also suggests the need for an intraocular pressure (IOP) check, a Humphrey visual field (HVF) test for the left eye, and disc photos. No mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08384",
"image_path": "slo_fundus_08384.jpg",
"filename": "data_08384.npz",
"report": "Patient has moderate primary open-angle glaucoma in the right eye and is a suspected case in the left eye. No known family history of glaucoma or prolonged steroid use. Cataract in both eyes and posterior vitreous detachment in left eye.",
"age": 79.81,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "1) moderate primary open angle glaucoma right eye, suspect left eye - referred by PERSON, asymmetric c/d ratio od>os. tmax 25/22. - no known fhx of glaucoma. no hx of long-term steroid use. - central corneal thickness 570s/580s - gonioscopy open - humphrey visual field with superior arcuate right eye, nonspecific changes left eye - optical coherence tomography retinal nerve fiber layer with s/i thinning right eye, full left eye - intraocular pressure 20/19 - concerning for moderate glaucoma right eye, suspect left eye - intraocular pressure goal midteens right eye, high teens left eye - great difficulty with gonioscopy so not a good selective laser trabeculoplasty candidate - recommend starting latanoprost qhs both eyes \u00ff 2. hyperopia ou, astigmatism ou, presbyopia - awaiting rx \u00ff 2. cataract both eyes - dfe next visit \u00ff \u00ff 3. posterior vitreous detachment left eye - monitor return to clinic DATE_TIME intraocular pressure/dfe \u00ff",
"gpt4_summary": "Patient has moderate primary open-angle glaucoma in the right eye and is a suspected case in the left eye. No known family history of glaucoma or prolonged steroid use. Cataract in both eyes and posterior vitreous detachment in left eye.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08385",
"image_path": "slo_fundus_08385.jpg",
"filename": "data_08385.npz",
"report": "Patient, a 79-year-old male with ckd & prostate cancer, has intermittent blurry vision due to dry eyes/blepharitis. Suffers from pco affecting vision & glare. Underwent yag capsulotomy treatment in his right eye. History shows laser treatment, high iop spikes post-cataract surgery, & familial glaucoma. Optic nerves are healthy but there's global depression; condition progressed. Intrigued at the prospect of surgery for vision-related mild ptosis & dermatochalasis, but currently deferred.",
"age": 79.69,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "79 y.o. male with ckd, prostate ca s/p rt # dry eyes / blepharitis -cause of intermittent blurry vision, improves with at. >at qid >at gel qhs prn >warm compresses / lid hygiene bid >omega-3 fatty acids # s/p phaco/pciol od DATE_TIME -has diffuse pco, symptomatic with blurry vision and glare at DATE_TIME >yag capsulotomy right eye; discussed r/b/a including risk of vision loss, glaucoma, inflammation, increased floaters, retinal detachment. pt verbalizes understanding and wishes to proceed. # h/o coag >DATE_TIME -prev followed by PERSON PERSON for DATE_TIME who is now retired. had been on drops in the past. -had laser procedure DATE_TIME and stopped drops -both parents had glaucoma -high iop spikes after cataract surgery ou -healthy appearing optic nerves with mild asymmetry -stable hvf since DATE_TIME; borderline changes on DATE_TIME with global depression os>od, similar to or slightly worse than DATE_TIME, progressed compared to DATE_TIME -oct DATE_TIME wnl -pachy 561/559 PERSON, open angles ou, no h/o trauma >monitor, repeat hvf after yag # s/p phaco/pciol os DATE_TIME # pco os s/p yag capsulotomy DATE_TIME -doing well # mild erm os -good foveal contour >monitor # posterior vitreous detachment ou -no tears/traction >rd precautions # mild ptosis and dermatochalasis -feels it is affecting vision and interested in surgical correction, but defers for now. >will refer to oculoplastics if patient wishes to pursue this rtc DATE_TIME: coe, hvf, oct nerve, bat",
"gpt4_summary": "Patient, a 79-year-old male with ckd & prostate cancer, has intermittent blurry vision due to dry eyes/blepharitis. Suffers from pco affecting vision & glare. Underwent yag capsulotomy treatment in his right eye. History shows laser treatment, high iop spikes post-cataract surgery, & familial glaucoma. Optic nerves are healthy but there's global depression; condition progressed. Intrigued at the prospect of surgery for vision-related mild ptosis & dermatochalasis, but currently deferred.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08386",
"image_path": "slo_fundus_08386.jpg",
"filename": "data_08386.npz",
"report": "The patient has pituitary macroadenoma with chiasmal compression but shows significant visual improvement after treatment. They are considered a glaucoma suspect, with mild retinal ganglion cell loss.",
"age": 46.1,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "mri from DATE_TIME was stable. DATE_TIME showed mild drop out of retinal ganglion cells ou (i.e. 'PERSON change). my exam showed no change. impression: 1. pituitary macroadenoma with chiasmal compression, status post trans-sphenoidal resection x 2 and proton bean radiation (DATE_TIME), with significant visual improvement after last intervention 2. glaucoma suspect recommendations: 1. consider obtaining over the counter reading glasses, likely a +1.00 or +1.25. 2. neuro-ophthalmology follow up in DATE_TIME or sooner if concerns arise this note was written with assistance from PERSON, neuro-ophthalmology fellow. ----- [administrative formulation. my impression of this case is based upon an assessment of the the patient's chronic problems as detailed under 'diagnoses' above that pose a threat to vision / neurological function or systemic health. my assessment of this case also included review of the following data: 1) results of tests and outside documents (specifically: a review of prior external notes; review of unique test results (including those described under 'ancillary studies' above); ordering unique tests; assessment requiring independent historian); 2) independent interpretation of tests performed by dr. PERSON; and 3) discussion or communication or management with dr. PERSON. with respect to management, this patient has a - high risk of morbidity related to therapy/elective or major surgery/decision regarding PERSON. - moderate risk of morbidity related to (drug management; minor surgery; treatment limited by social determinants or health). i spent a total of greater than (DATE_TIME preparing for, caring for (face-to-face and non face-to-face), formulating (including review of the presentation with the resident or fellow or of medical tests) and finalizing the visit for this patient.]",
"gpt4_summary": "The patient has pituitary macroadenoma with chiasmal compression but shows significant visual improvement after treatment. They are considered a glaucoma suspect, with mild retinal ganglion cell loss.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08387",
"image_path": "slo_fundus_08387.jpg",
"filename": "data_08387.npz",
"report": "The note does not provide information on the presence of glaucoma. It discusses a patient requesting a second HVF test and the results worsening.",
"age": 76.7,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "test os first) pt often requests a second round of hvf and the results look worse due to PERSON scribing for dr. Person i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "The note does not provide information on the presence of glaucoma. It discusses a patient requesting a second HVF test and the results worsening.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08390",
"image_path": "slo_fundus_08390.jpg",
"filename": "data_08390.npz",
"report": "Patient post phaco/iol, has enlarged c/d, previously on Xalatan. Noted with blepharitis and possible early glaucoma signs. Considering restarting Xalatan, consulting Glaucoma service.\n",
"age": 80.07,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "imp: s/p phaco/iol ou at ophtho in new LOCATION enlarged c/d -- was on xalatan but self d/c'd; PERSON DATE_TIME blepharitis ou hvf od with sup temp defect and possible early nasal step with thinning on rnfl consider restarting xalatan vs repeat hvf in DATE_TIME i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow. i have reviewed the resident/fellow's notes and made any necessary changes. will consult glaucoma service (may also need neuro-oph opinion)",
"gpt4_summary": "Patient post phaco/iol, has enlarged c/d, previously on Xalatan. Noted with blepharitis and possible early glaucoma signs. Considering restarting Xalatan, consulting Glaucoma service.\n",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08391",
"image_path": "slo_fundus_08391.jpg",
"filename": "data_08391.npz",
"report": "64-year-old white, non-Hispanic male patient. He has no diagnosis of glaucoma. Patient's gateway account is activated and ready for use.",
"age": 64.17,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "legally separated",
"note": "a 64 y.o. white, non-hispanic male with no diagnosis of glaucoma. patient gateway activation information your account is ready to use. activate your account using following steps:",
"gpt4_summary": "64-year-old white, non-Hispanic male patient. He has no diagnosis of glaucoma. Patient's gateway account is activated and ready for use.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08400",
"image_path": "slo_fundus_08400.jpg",
"filename": "data_08400.npz",
"report": "The patient is a 54 y.o. female suspected glaucoma due to cup to disc ratio high in myopia. She's on latanoprost for eye treatment. A right cataract is also noted.",
"age": 54.41,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "first seen by dr. PERSON on DATE_TIME glaucoma medication intolerances: none target iop: DATE_TIME, tmax: 21 / 21 central corneal thickness: 563 / 565 gonioscopy: d35f 1+ ou retinal nerve fiber layer, right eye: inf thinning retinal nerve fiber layer, left eye: sup/inf thinning visual fields, right eye: inferior > superior arcuate-like depression visual fields, left eye: superior arcuate-like depression, inferior nasal step, enlarged blind spot family history: none steroids: none trauma: none asthma/copd: none other medical history and problems: generally healthy assessment/plan: 54 y.o. female software engineer # glaucoma suspect due to cup to disc ratio, both eyes - tilted nerves, evaluation complicated by high myopia - dr. PERSON started PERSONop acceptable ou - continue latanoprost qhs ou; low threshold to escalate therapy od - return in DATE_TIME for iop check # high myopia, both eyes; operculated hole, right eye - no underlying fluid, hole appears chronic and pigmented - next appointment with PERSON PERSON DATE_TIME # cataract, right > left eye - approaching visually significance, monitor, particularly psc od karen hong, LOCATION___________________ i saw and evaluated this patient and discussed the case as appropriate with the fellow. i have reviewed the fellow's notes and made any necessary changes. PERSON scribing for dr. PERSON i attest that i was present while this encounter was recorded and agree that the information entered by my scribe and updated by me is complete and accurate. PERSON, md",
"gpt4_summary": "The patient is a 54 y.o. female suspected glaucoma due to cup to disc ratio high in myopia. She's on latanoprost for eye treatment. A right cataract is also noted.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08401",
"image_path": "slo_fundus_08401.jpg",
"filename": "data_08401.npz",
"report": "Patient suspected of glaucoma based on cup to disc ratio, with no family history of condition. Also presents dry eye, resolved chemical keratitis. Plan refers to glaucoma service.",
"age": 42.96,
"gender": "male",
"race": "white",
"ethnicity": "unknown",
"language": "unknown",
"maritalstatus": "married or partnered",
"note": "# glaucoma suspect based on cup to disc ratio - no family history - cct thick - hvf with new LOCATION defect od - oct rnfl demonstrates progression of inferior thinning ou # dry eye ou - uses pf ats rarely # chemical keratitis od - resolved plan: - pf ats, wcs - refer to glaucoma service for management \u00ff PERSON, pgy-2 i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow. i have reviewed the resident/fellow's notes and made any necessary changes.",
"gpt4_summary": "Patient suspected of glaucoma based on cup to disc ratio, with no family history of condition. Also presents dry eye, resolved chemical keratitis. Plan refers to glaucoma service.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08404",
"image_path": "slo_fundus_08404.jpg",
"filename": "data_08404.npz",
"report": "The patient, Taye Ige, doesn't smoke and has prescriptions for glasses sphere +2.00 right, +2.50 left. He has allergies to chloroquine hcl, is on aspirin, atenolol and triamcinolone acetonide. No mention of glaucoma.",
"age": 52.91,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "taye ige date of birth: DATE_TIME patient PERSON: NUMBER Institution LOCATION phone #: PHONE_NUMBER dept fax #: PHONE_NUMBER taye ige DATE_TIME office visit mrn: NUMBER provider: PERSON, LOCATION: Institution comprehensive oph main campus patient demographics address phone e-mail address #4, femi deru close, PERSON, LOCATION, LOCATION unavailable EMAIL_ADDRESS information date of birth sex race ethnicity preferred language preferred written language DATE_TIME male black or NRP no NRP NRP reason for visit none vital signs/measurements smoking status never smoker most recent eyeglasses prescription (DATE_TIME) sphere cylinder add right LOCATION sphere +2.00 left +2.50 sphere +2.00 allergies as of DATE_TIME chloroquine hcl medications and orders your current medications aspirin 81 mg ec tablet take 81 mg by mouth DATE_TIME. atenolol (tenormin) 50 mg tablet take 1 tablet (50 mg total) by mouth DATE_TIME. triamcinolone acetonide 0.1 % ointment apply topically 2 (two) times a day for DATE_TIME. your orders normal orders this visit color fundus photography - ou - both eyes humphrey visual field - ou - both eyes oct, optic nerve - ou - both eyes - condition list as of DATE_TIME family history of diabetes mellitus hypertension trigeminal neuralgia of left side of face right leg pain results summary immunizations administered on date of encounter - DATE_TIME none",
"gpt4_summary": "The patient, Taye Ige, doesn't smoke and has prescriptions for glasses sphere +2.00 right, +2.50 left. He has allergies to chloroquine hcl, is on aspirin, atenolol and triamcinolone acetonide. No mention of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08416",
"image_path": "slo_fundus_08416.jpg",
"filename": "data_08416.npz",
"report": "The patient is taking Simvastatin. They have osteoarthritis in the hip, a colon polyp, hyperlipidemia, a heart murmur, snoring, and a lung nodule. They also have high blood pressure but no glaucoma diagnosis.",
"age": 66.09,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "available; details: dispense: capsule(s); date: DATE_TIME PERSON DATE_TIME 8:39 am needs PERSON. metal med transfer process. simvastatin (zocor) 10 mg tablet (taking) take 1 tablet by mouth DATE_TIME ( discontinue 20mg) your orders normal orders this visit humphrey visual field - ou - both eyes oct, optic nerve - ou - both eyes - cirrus; optic disc; 6mm length; no condition list as of DATE_TIME osteoarthritis of hip colon polyp hyperlipidemia heart murmur snoring lung nodule healthcare maintenance elevated blood pressure reading without diagnosis of hypertension results summary immunizations administered on date of encounter - DATE_TIME none",
"gpt4_summary": "The patient is taking Simvastatin. They have osteoarthritis in the hip, a colon polyp, hyperlipidemia, a heart murmur, snoring, and a lung nodule. They also have high blood pressure but no glaucoma diagnosis.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08417",
"image_path": "slo_fundus_08417.jpg",
"filename": "data_08417.npz",
"report": "Untreated Glaucoma condition noted, patient previously used Xalatan. Intolerant to many. Glaucoma procedures considered. Also has cataract. Plan to start IOP, OCT check in 2 mo.",
"age": 61.54,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "1. , ou has gone untreated x DATE_TIME; tmax DATE_TIME; cct not known at this time. was intolerant to many PERSON was previously on xalatan prior to going to LOCATION glaucoma procedures: od: LOCATION os: ltp 2. PERSON cataract, ou plan: start PERSON will get iop --oct check 2 mo",
"gpt4_summary": "Untreated Glaucoma condition noted, patient previously used Xalatan. Intolerant to many. Glaucoma procedures considered. Also has cataract. Plan to start IOP, OCT check in 2 mo.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08419",
"image_path": "slo_fundus_08419.jpg",
"filename": "data_08419.npz",
"report": "66 y.o. white, non-hispanic male. No diagnosis of glaucoma.",
"age": 66.88,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "a 66 y.o. white, non-hispanic male with no diagnosis of glaucoma.",
"gpt4_summary": "66 y.o. white, non-hispanic male. No diagnosis of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08422",
"image_path": "slo_fundus_08422.jpg",
"filename": "data_08422.npz",
"report": "37-year-old white, non-Hispanic male with no diagnosis of glaucoma. Encounter details are recorded accurately.",
"age": 37.67,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "a 37 y.o. white, non-hispanic male with no diagnosis of glaucoma. scribe for PERSON on DATE_TIME at DATE_TIME am. i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "37-year-old white, non-Hispanic male with no diagnosis of glaucoma. Encounter details are recorded accurately.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08423",
"image_path": "slo_fundus_08423.jpg",
"filename": "data_08423.npz",
"report": "The patient has glaucoma and is on various medications: timolol (1x/night), brimonidine (2x/day), dorzolamide (3x/day), and netarsudil (1x/night). Alternative medication options mentioned. Emphasizes calling glaucoma dept. for queries.",
"age": 76.06,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "medication route frequency LOCATION (teal) both eyes 1x/night timolol1 (yellow) both eyes 2x/day brimonidine3 (purple) both eyes 3x/day dorzolamide (orange)& both eyes 3x/day netarsudil (white)4 both eyes 1x/night \u00f8 some medications that may be prescribed in lieu of this medication include: latanoprost, xalatan, travatan z, travaprost, LOCATION, LOCATION, LOCATION/tafluprost (preservative-free). 1 some medications that may be prescribed in lieu of this medication include: timolol timoptic, timoptic xe = timolol gel-forming solution (gfs), betoptic s, LOCATION, LOCATION, ocudose (preservative-free). & some medications that may be prescribed in lieu of this medication include: dorzolamide, trusopt, PERSON, brinzolamide. 3 some medications that may be prescribed in lieu of this medication include: brimonidine, alphagan, PERSON 4 this medication is also known as rhopressa. always wait DATE_TIME (by the clock) in between eye drops. please bring this to your next visit. for routine questions, please call PHONE_NUMBER (LOCATION, ask for glaucoma department) or PHONE_NUMBER (longwood). for emergencies, please call PHONE_NUMBER and ask for the glaucoma physician on-call.",
"gpt4_summary": "The patient has glaucoma and is on various medications: timolol (1x/night), brimonidine (2x/day), dorzolamide (3x/day), and netarsudil (1x/night). Alternative medication options mentioned. Emphasizes calling glaucoma dept. for queries.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08425",
"image_path": "slo_fundus_08425.jpg",
"filename": "data_08425.npz",
"report": "76-year-old woman has pseudoexfoliation glaucoma (worse in right eye), managed successfully with current regimen. Underwent successful cataract surgery and YAG laser treatment. Has latex allergy.",
"age": 76.83,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "76 yo woman with pxf (od>os) 1. pseudoexfoliation glaucoma (od>os) - iop acceptable ou with PERSON DATE_TIME. cpm with PERSON. oct stable ou. iop's stable on current regimen. cpm. 2. pseudophakia ou -- patient has done very well with with cataract surgery at wills with excellent visual outcomes ou. had yag laser on DATE_TIME (PERSON) with excellent outcome os and 8-9-16 od. vision excellent 3. shortness of breath on metoprolol -- discontinued by pcp DATE_TIME. doing well on cosopt 4. blepharitis (os>od). some irritation os although corneas look good and no evidence of inflammation in ac. rec wc/lh with artificial tears. - allergic to latex 5. syncopal episode on DATE_TIME. etiology unknown. broke hip and was in LOCATION for DATE_TIME and then DATE_TIME at spaulding. now staying in handicapped room at a residence inn in LOCATION, LOCATION. there was a question of whether this episode could possibly be due to any of her eye drops. while it is a possibility that the beta blocker could have contributed, the pt has been on a topical beta blocker for DATE_TIME with no untoward effects. comprehensive workup while at Institution has not revealed any underlying etiology for the syncope. heart rate was normal with no shortness of breath in epic notes so no evidence of bradycardia secondary to the cosopt. if bradycardia develops or additional sycopal episodes, will try off of timolol. will see dr. PERSON 6-26-17 for ongoing follow up. began weight bearing on right leg DATE_TIME and still using walker. follow up here in DATE_TIME for iop check",
"gpt4_summary": "76-year-old woman has pseudoexfoliation glaucoma (worse in right eye), managed successfully with current regimen. Underwent successful cataract surgery and YAG laser treatment. Has latex allergy.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08427",
"image_path": "slo_fundus_08427.jpg",
"filename": "data_08427.npz",
"report": "Patient with history of left optic nerve glioma, currently stable. Visual function is good (20/15 ou). She's followed for panhypopituitarism post-radiation. Glaucoma is suspected; OCT imaging used.",
"age": 25.99,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "formulation: the patient has a history of a left optic nerve glioma which extended to the chiasm, status post biopsy and proton beam radiotherapy (DATE_TIME). her visual function has been stable with excellent acuity (20/15 ou), thought with a questionable left afferent pupillary defect. her visual fields DATE_TIME, which i repeated because of poor technical performance initially, demonstrated a similar left nasal field and right superior temporal areas of decreased sensitivity. she continues to be followed by neuroendocrinology for panhypopituitarism and PERSON following radiation therapy. her most recent imaging last june/2016 was also stable. she is a glaucoma suspect, and i recommended oct with ganglion cell segmentation as a means to help follow her status. there is the confounding factor of the degree to which any ganglion cell loss that is identified would be secondary to the tumor/surgery/radiation, but this test will be useful to follow her course going forward, especially if the tumor remains dormant. the oct showed significant loss of the gcl/ipl complex bilaterally, with nasal loss od, which is more suggestive of glioma as the causative mechanism rather than glaucoma. impression: 1. optic pathway glioma involving the left optic nerve and extending to the chiasm, s/p two craniotomies (for a biopsy, then post-operative 'leakage') and proton beam radiation (DATE_TIME), stable 2. panhypopituitarism, secondary to #1 3. glaucoma suspect 4. polycystic ovarian disorder plan: 1. follow-up neuro-ophthalmic examination in DATE_TIME. repeat mri brain DATE_TIME. color photographs/DATE_TIME",
"gpt4_summary": "Patient with history of left optic nerve glioma, currently stable. Visual function is good (20/15 ou). She's followed for panhypopituitarism post-radiation. Glaucoma is suspected; OCT imaging used.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08430",
"image_path": "slo_fundus_08430.jpg",
"filename": "data_08430.npz",
"report": "The patient has a high risk of morbidity related to therapy, surgery or decisions. Moderate risk exists from drug management, minor surgery, or treatment limited by social health factors. No mention of glaucoma.",
"age": 69.76,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "(this note was prepared with the assistance of PERSON, neuro-ophthalmology fellow.) ----- [administrative formulation. my impression of this case is based upon an assessment of the the patient's acute / chronic problems as detailed under 'diagnoses' above that pose a threat to vision / neurological function or systemic health. my assessment of this case also included review of the following data: 1) results of tests and outside documents (specifically: a review of prior external notes; review of unique test results (including those described under 'ancillary studies' above); ordering unique tests; assessment requiring independent historian); 2) independent interpretation of tests performed by PERSON ; and 3) discussion or communication or management with dr. . with respect to management, this patient has a - high risk of morbidity related to therapy/elective or major surgery/decision regarding PERSON. - moderate risk of morbidity related to (drug management; minor surgery; treatment limited by social determinants or health). i spent a total of greater than (DATE_TIME preparing for, caring for (face-to-face and non face-to-face), formulating (including review of the presentation with the resident or fellow or of medical tests) and finalizing the visit for this patient.]",
"gpt4_summary": "The patient has a high risk of morbidity related to therapy, surgery or decisions. Moderate risk exists from drug management, minor surgery, or treatment limited by social health factors. No mention of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08432",
"image_path": "slo_fundus_08432.jpg",
"filename": "data_08432.npz",
"report": "22 y.o male with history of primary open-angle glaucoma (POAG) has increased cup-to-disc ratio; treated with drops. Elevated intraocular pressure (IOP) reportedly well-controlled. OCT & HVF normal.",
"age": 22.88,
"gender": "male",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "unknown",
"note": "22 y.o. m 1. poag (s) based on inc c:d ratio ou was treated with drops by PERSON PERSON at chb x DATE_TIME (DATE_TIME), none since h/o elevated iop tmax unknown iop controlled ou DATE_TIME hvf full ou oct wnl ou dp stable observe discussed risk of glaucoma and recommended follow up DATE_TIME. refractive error: a prescription for new glasses was given to the patient DATE_TIME. f/u DATE_TIME, mrx, iop, hvf, LOCATION, oct an dp",
"gpt4_summary": "22 y.o male with history of primary open-angle glaucoma (POAG) has increased cup-to-disc ratio; treated with drops. Elevated intraocular pressure (IOP) reportedly well-controlled. OCT & HVF normal.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08433",
"image_path": "slo_fundus_08433.jpg",
"filename": "data_08433.npz",
"report": "Clinical notes indicate slow progression in the patient's condition. Further tests are planned including dilation and IOP check. Presence of glaucoma is not stated.",
"age": 70.71,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "miller for retina care. -long discussion with patient on DATE_TIME: given slow progression on oct and disc photos over DATE_TIME, i recommended PERSON to the low teens. -rtc in DATE_TIME with iop check ou, hvf os, dilation ou, and oct rnfl/gcc ou, sooner prn. the information above was documented by PERSON as a scribe for PERSON on DATE_TIME.",
"gpt4_summary": "Clinical notes indicate slow progression in the patient's condition. Further tests are planned including dilation and IOP check. Presence of glaucoma is not stated.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08434",
"image_path": "slo_fundus_08434.jpg",
"filename": "data_08434.npz",
"report": "The patient is a female with Graves' disease and mild symptoms. Her HbA1c level is 7.2% indicating diabetes. She also has a history of scleritis and hyperopia. Glaucoma is not mentioned.",
"age": 66.11,
"gender": "female",
"race": "white",
"ethnicity": "hispanic",
"language": "english",
"maritalstatus": "single",
"note": "PERSON is a DATE_TIME. female graves disease diagnosed with graves PERSON. hamnvik at bwh reports 'fairly mild'. PERSON hvf 24-2: full ou dm2 deferred dilation so she does not accidentally vote for the wrong candidate DATE_TIME! PERSON taken. a1c is good. no bdr. hgb a1c date value ref range status DATE_TIME 7.2 (h) 4.2 - 5.6 % final comment: hba1c levels 5.7-6.4% represent pre-diabetes, indicating impaired glucose control and an increased risk of developing diabetes. the diagnostic hba1c level for diabetes is 6.5% or greater. hba1c levels <4.2% may indicate a hemoglobinopathy or anemia, and an alternative method is recommended to monitor glucose control. hemoglobin a1c date value ref range status DATE_TIME (h) 4.2 - 5.6 % final comment: hba1c levels 5.7-6.4% represent pre-diabetes, indicating impaired glucose control and an increased risk of developing diabetes. the diagnostic hba1c level for diabetes is 6.5% or greater. hba1c levels <4.2% may indicate a hemoglobinopathy or anemia, and an alternative method is recommended to monitor glucose control. h/o scleritis ou not symptomatic. hyperopia with presbyopia new rx given. f/u in DATE_TIME for hvf 24-2, oct, NRP, ar/refract. by signing my name below, i, PERSON, acting as a scribe, attest that this documentation has been prepared under the direction and in the presence of PERSON, LOCATION DATE_TIME by signing my name below, i, PERSON, attest that this documentation has been prepared under my direction.",
"gpt4_summary": "The patient is a female with Graves' disease and mild symptoms. Her HbA1c level is 7.2% indicating diabetes. She also has a history of scleritis and hyperopia. Glaucoma is not mentioned.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08437",
"image_path": "slo_fundus_08437.jpg",
"filename": "data_08437.npz",
"report": "The patient had IIH which is now resolved, and optic asymmetry, currently asymptomatic. She has lost 35 pounds, assisting her improvements. No diamox needed. Glaucoma not mentioned.",
"age": 21.49,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "unknown",
"note": "double vision or pulsatile tinnitus. she probably improved by loosing weight as she reports she has lost 35 pounds since DATE_TIME. she can stay off diamox and hopefully continue to loose weight and let us know if she had her prior iih symptoms recurrence. diagnoses. 1. iih, currently resolved 2. optic PERSON left>right currently asymptomatic recommendations. 1. follow up in DATE_TIME. stay off diamox 3. encourage weight loss PERSON, PERSON, neuro-ophthalmology service (this note was prepared with the assistance of PERSON, md, neuro-ophthalmology fellow.) ----- [administrative formulation. my impression of this case is based upon an assessment of the the patient's problems as detailed under 'diagnoses' (listed above) that pose a threat to vision, neurological function or systemic health. my assessment of this case also included review of the following data: 1) results of tests and outside documents; review of unique test results (including those described under 'ancillary studies' above); ordering unique tests; assessment requiring independent historian, her father); 2) independent interpretation of tests performed by dr. ***; and 3) discussion or communication of management with dr. PERSON. with respect to management, this patient has a - potentially high risk of visual or neurological morbidity related to the above diagnoses and considerations of management. - potentially moderate risk of visual or neurological morbidity related to the above diagnoses and considerations of management (including treatment limited by social determinants or health). i spent a total of greater than (DATE_TIME preparing and caring for this patient (face-to-face and non face-to-face); formulating (including review of the presentation with the resident or fellow or review of medical tests) and finalizing the note.]",
"gpt4_summary": "The patient had IIH which is now resolved, and optic asymmetry, currently asymptomatic. She has lost 35 pounds, assisting her improvements. No diamox needed. Glaucoma not mentioned.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08438",
"image_path": "slo_fundus_08438.jpg",
"filename": "data_08438.npz",
"report": "Patient has ocular hypertension with intraocular pressure of 27, low risk but untreated. Reviewed & opted for selective laser trabeculoplasty. Stable, high corneal hysteresis.",
"age": 63.38,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "first seen by PERSON PERSON on DATE_TIME diagnosis: ocular hypertension referred by optometry (dr. LOCATION) target iop: 23/23, tmax: 34 (DATE_TIME) / 33 (DATE_TIME) central corneal thickness: 561 / 566 corneal hysteresis: 10.0 / 11.0 gonioscopy: refractive error: od . . / os . . optic nerve findings on initial visit right eye: optic nerve findings on initial visit left eye: visual fields on initial visit right eye: visual fields on initial visit left eye: medication history and intolerances at first visit: glaucoma procedures right eye: glaucoma procedures left eye: other eye procedures right eye: other eye procedures left eye: other eye problems right eye: myopia, cl wearer other eye problems left eye: myopia, cl wearer family history: ?pgm steroids: no trauma: no asthma: no other medical history and problems: initial note: ocular hypertension with low risk, but intraocular pressure of 27 DATE_TIME and DATE_TIME untreated. central corneal thickness around 550. reviewed treatment options and would like to pursue selective laser trabeculoplasty plan: pressure right eye just above target and left eye below target; responded well to selective laser trabeculoplasty high corneal hysteresis (10.0/11.0) looks great and stable return to clinic in DATE_TIME for intraocular pressure check and hvf i personally saw and examined the patient and reviewed the findings and agree with what is documented in the record. i discussed the patient with the resident and agree with their note which accurately reflects my own findings and plan.",
"gpt4_summary": "Patient has ocular hypertension with intraocular pressure of 27, low risk but untreated. Reviewed & opted for selective laser trabeculoplasty. Stable, high corneal hysteresis.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08440",
"image_path": "slo_fundus_08440.jpg",
"filename": "data_08440.npz",
"report": "The male patient is a new glaucoma suspect due to family history and intraocular pressure (IOP). His CCT is normal, but OCT RNFL is slightly thin. He has started latanoprost for treatment.",
"age": 60.32,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "unknown",
"note": "PERSON is a DATE_TIME. male is a new patient to me and presents for a comprehensive eye exam. he was last seen by dr. PERSON on DATE_TIME. his sister is our tech PERSON. \u00ff open angle glaucoma glaucoma suspect based on family history, iop and PERSON DATE_TIME tmax - 23/23 cct - LOCATION - within normal limits od, thin os gonio: open angle, not occludable ou family history - + mother last hvf 24-2: wnl ou last oct rnfl slightly thin ou, slightly thin gcl superior ou start latanoprost qhs ou cataract ou not visually significant observe at this time hyperopia with astigmatism and presbyopia optional mrx dispensed otc equivalence handout given can continue otc readers or use rx f/u in DATE_TIME for iop check, no dilation, optos",
"gpt4_summary": "The male patient is a new glaucoma suspect due to family history and intraocular pressure (IOP). His CCT is normal, but OCT RNFL is slightly thin. He has started latanoprost for treatment.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08442",
"image_path": "slo_fundus_08442.jpg",
"filename": "data_08442.npz",
"report": "70 y.o. white, non-hispanic male diagnosed with glaucoma. Also had phone COVID screen.",
"age": 70.47,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "a 70 y.o. white, non-hispanic male was evaluated and diagnosed with glaucoma. phone covid screen",
"gpt4_summary": "70 y.o. white, non-hispanic male diagnosed with glaucoma. Also had phone COVID screen.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08444",
"image_path": "slo_fundus_08444.jpg",
"filename": "data_08444.npz",
"report": "Patient has mild stage primary open-angle glaucoma (POAG). Cupping isn't impressive, but there is nerve fiber layer (NFL) loss in left eye. Left visual field defect consistent with NFL dropout. Taking latanoprost but recommended to stop briefly to check untreated intraocular pressure (IOP), which is currently 11 in both eyes. Family history of glaucoma in father. Follow up scheduled.",
"age": 61.9,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "poag mild stage tmax unknown; cct DATE_TIME. on LOCATION but not adherent. while cupping is not impressive there is nfl loss os that can be appreciated on the disc photo and oct. the vf defect os is c/w nfl dropout PERSONfh in father ?hx steroids for asthma, but not currently using any inhalers no eye trauma started on latanoprost DATE_TIME, iop 11/11 today hvf unremarkable right, left with inferior depressions no correlated with exam plan: rec stopping latanoprost for holiday to determine true untreated iop follow up DATE_TIME for an iop ck.",
"gpt4_summary": "Patient has mild stage primary open-angle glaucoma (POAG). Cupping isn't impressive, but there is nerve fiber layer (NFL) loss in left eye. Left visual field defect consistent with NFL dropout. Taking latanoprost but recommended to stop briefly to check untreated intraocular pressure (IOP), which is currently 11 in both eyes. Family history of glaucoma in father. Follow up scheduled.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08449",
"image_path": "slo_fundus_08449.jpg",
"filename": "data_08449.npz",
"report": "76 y.o. female, glaucoma suspect due to cup: disc appearance. Open angles ou, borderline might be related to dermatochalasis. Risks of acute angle closure glaucoma discussed. Cataracts might narrow angles in future. Nuclear senile cataract ou impacting vision.\n",
"age": 76.98,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "76 y.o. female with h/o oa, paf, pe, hypertension considering complete right shoulder replacement vs shoulder repair friend had lost left eye to ?glaucoma - glaucoma suspect based on cup: disc appearance ou fam hx: +brother tmax: 18/18 (22 by tonopen in plastics clinic) cct: gonio DATE_TIME: ou open to ss/ptm hvf DATE_TIME: ou with borderline superior defects possibly related to dermatochalasis DATE_TIME: od nonspecific inferior defect, os rim defect rnfl DATE_TIME: ou wnl DATE_TIME: od borderline superior, PERSON (likely stable with decreased avg thickness related to decreased signal strength) disc photos: DATE_TIME last dilated: DATE_TIME >> monitor off eyedrops for now - narrow angles ou not occludable by gonioscopy DATE_TIME postdilation iop (DATE_TIME) was unchanged at 16/17 >> monitor. signs & symptoms of acute angle closure glaucoma discussed. also discussed that as cataracts grow her angles may become occludable in future at which time a laser peripheral iridotomy would be recommended - nuclear senile cataract ou becoming visually significant with glare when driving at DATE_TIME but states still doing ok for now. follows white lines on roads >> observe; bat each visit ? ?- posterior vitreous detachment od, syneresis os seen by dr. PERSONME for floater od; previously noted pvd in that eye >> retinal detachment precautions - s/p rll cyst removal by dr. PERSON ??f/up DATE_TIME with bat, hvf, cct, dilation, sooner prn",
"gpt4_summary": "76 y.o. female, glaucoma suspect due to cup: disc appearance. Open angles ou, borderline might be related to dermatochalasis. Risks of acute angle closure glaucoma discussed. Cataracts might narrow angles in future. Nuclear senile cataract ou impacting vision.\n",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08451",
"image_path": "slo_fundus_08451.jpg",
"filename": "data_08451.npz",
"report": "The patient may have late post-radiation optic neuropathy related to previous radiation therapy (17000 gy) for squamous cell carcinoma. Considered treatment for optic nerve radiation injury. No mention of glaucoma.",
"age": 61.84,
"gender": "male",
"race": "white",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "married or partnered",
"note": "did not demonstrate significant improvement. it remains possible that this could represent a late post-radiation optic neuropathy, and review of his radonc notes from DATE_TIME clarifies that he did receive a total radiation dose of 17000 gy at that time. we discussed that we would like to discuss his case at our management conference to determine possible options, including limited case reports suggesting some success in treating optic nerve radiation injury with PERSON (as has been used more widely for radiation injury elsewhere in the cns). in the meantime, he can taper the prednisone, and we will repeat mri brain/orbits to assess for any interval evolution of the right optic nerve enhancement. impression: 1. optic neuropathy od, unclear etiology, possibly secondary to prior radiation 2. history of radiation therapy in DATE_TIME (17000 gy) for right sided squamous cell carcinoma of the neck secondary to oral DATE_TIME. history of tick bites yearly, self treats with one dose of oral doxycycline 4. PERSON. history of macula-on retinal detachment s/p pr in DATE_TIME plan: 1. taper prednisone over DATE_TIME. repeat mri brain and orbits 3. oct optic nerve (rnfl and gcc) DATE_TIME. repeat neuro-ophthalmic exam pending mri result (this note was prepared with the assistance of makayla mccoskey, md) dean PERSON, PERSON neuro-ophthalmology LOCATION PHONE_NUMBER fax PHONE_NUMBER",
"gpt4_summary": "The patient may have late post-radiation optic neuropathy related to previous radiation therapy (17000 gy) for squamous cell carcinoma. Considered treatment for optic nerve radiation injury. No mention of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08453",
"image_path": "slo_fundus_08453.jpg",
"filename": "data_08453.npz",
"report": "65 y.o. female has primary open-angle glaucoma (POAG) based on increased c:d ratio and history of elevated intraocular pressure (IOP). Family history includes 2 uncles, 1 aunt and grandmother with glaucoma. Bilateral monocular diplopia. Dry eyes.",
"age": 65.15,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "65 y.o. female f/u glaucoma testing 1. poag(s) based on increased c:d ratio ou, od od - pachymetry (585/578); tmax (13/16); ? fhx of glaucoma (father) - hvf with nonspecific changes ou - oct-rnfl (83/77) wnl ou - tg = mid teens ou ? - follow without eye drop therapy for now ? # dm2 - no npdr or csme - bp and bs control - sees dr. PERSON at joslin yearly # cataract ou - not visually significant - follow social/systemic: dm2 ? rtc DATE_TIME with hvf ou and disc photos ou",
"gpt4_summary": "Patient is suspected of having open angle glaucoma, more in left eye than right. The father has a history of glaucoma. No specific changes in visual fields identified. OCT-RNFL results normal. No immediate eye drop therapy required. Patient also has type 2 diabetes and cataracts, both under control.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08482",
"image_path": "slo_fundus_08482.jpg",
"filename": "data_08482.npz",
"report": "Patient's intraocular pressure (IOP) managed with timolol. SLT performed on both eyes. Still above IOP goal. Could consider Rhopressa in future. Potential candidate for phaco/migs. Glaucoma not specifically mentioned.",
"age": 72.93,
"gender": "female",
"race": "white",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "single",
"note": "pressure less than or equal to 17 mmhg, right eye. -goal intraocular pressure less than or equal to 17 mmhg, left eye. -iop at goal od and at goal os on DATE_TIME on timolol bid ou and s/p slt ou. -continue timolol bid ou. -instructions written out for patient (see table/details under patient instructions) previously. -emphasized adherence to medication regimen. -preservative-free artificial tears as needed. -patient is good phaco/migs candidate when she's ready to have ce/iol. -long discussion with patient on DATE_TIME: patient's iop is still above goal. she never started rhopressa as her mother who is in her DATE_TIME suffered a broken hip, and she has been busy. we decided to give slt a try given multiple medication allergies. we proceeded with slt od 180\u00f8 starting at 0.4 mj given highly pigmented tm on DATE_TIME. -long discussion with patient on DATE_TIME: given her good initial response s/p slt od (8-point drop), we proceeded with slt os 180\u00f8 starting at 0.4 mj given highly pigmented tm on DATE_TIME. -long discussion with patient on DATE_TIME: patient's ~90 y/o mother has a h/o of macular degeneration without a current provider to follow-up; i provided her with contact information to several PERSON providers and recommended that her mother seek out phaco/pciol given poor vision in her only eye. -rtc in DATE_TIME with iop check, arx, bat, optical biometry, and disc photos ou, sooner prn. if iop spike in future, consider rhopressa qhs ou versus PERSON (knowing irides may change color). consider phaco/migs in the future once patient is bothered by vision. the information above was documented by Person as a scribe for PERSON on DATE_TIME.",
"gpt4_summary": "Patient's intraocular pressure (IOP) managed with timolol. SLT performed on both eyes. Still above IOP goal. Could consider Rhopressa in future. Potential candidate for phaco/migs. Glaucoma not specifically mentioned.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08486",
"image_path": "slo_fundus_08486.jpg",
"filename": "data_08486.npz",
"report": "Patient has diffuse large B cell lymphoma, seizures, right homonymous hemianopia, binocular horizontal diplopia, and dry eyes. Glaucoma is suspected in right eye due to elevated intraocular pressure and increased cup:disc ratio.",
"age": 71.79,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "impression: 1. diffuse large b cell lymphoma with intracranial intravascular lymphoma, ischemic infarcts, DATE_TIME, chemo completed DATE_TIME, subclinical seizures in the left temporal lobe (controlled now with LOCATION and briviact) 2. right homonymous hemianopia secondary to #1 3. binocular horizontal diplopia, worse at near > far, likely due to convergence insufficiency 4. glaucoma suspect od, with elevated intraocular pressure od and increased cup:disc ratio od>os ?5. pciol opacification os > od 6. dry eyes os > od recommendations: 1. prescribed timolol drops twice a day only in the right eye 2. she will find a local ophthalmologist (and notify us if she needs a referral to PERSON), to assess for intraocular pressures, pciol opacification os > od, and dry eyes 3. preservative-free artificial eye drops ou 4. oct and fundus photos DATE_TIME. neuro-ophthalmic follow up in DATE_TIME (this note was prepared with the assistance of PERSON, neuro-ophthalmology fellow.) it is a pleasure to participate in the care of this patient. please do not hesitate to call with questions. ? sincerely, ? PERSON, PERSON spent DATE_TIME with this patient, more than 50% of which was face to face with the patient.",
"gpt4_summary": "Patient has diffuse large B cell lymphoma, seizures, right homonymous hemianopia, binocular horizontal diplopia, and dry eyes. Glaucoma is suspected in right eye due to elevated intraocular pressure and increased cup:disc ratio.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08487",
"image_path": "slo_fundus_08487.jpg",
"filename": "data_08487.npz",
"report": "Patient has cupping in both eyes, no glaucoma detected. HVF and OCT are normal. No intraocular pressure elevation. Also has cataracts and PVD in both eyes, and refractive error.",
"age": 75.37,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "Imp: cupping ou, as before; normal hvf and oct today; no iop elevation; av cct Cataract ou pvd ou refr error Plan: yrly with hvf and oct rx=m",
"gpt4_summary": "Patient has cupping in both eyes, no glaucoma detected. HVF and OCT are normal. No intraocular pressure elevation. Also has cataracts and PVD in both eyes, and refractive error.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08488",
"image_path": "slo_fundus_08488.jpg",
"filename": "data_08488.npz",
"report": "31 y.o. male is a glaucoma suspect due to increased c:d ratio. His intraocular pressure is controlled, goal 21 or less. Family history positive for glaucoma.",
"age": 31.17,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "31 y.o. male 1. glaucoma suspect based on inc c:d ratio ou cct thick hvf full oct wnl dp stable c/w 2014 iop controlled (goal 21 or less ou) fhx + maternal aunts/uncles observe rec DATE_TIME eye exam 2. refractive error: a prescription for new glasses was given to the patient DATE_TIME. 3. PERSON wear (sports) contact lens hygiene was reviewed with the patient including regular cleaning and changing of lenses and avoiding sleeping in contacts. patient was instructed to discontinue contact lens use with any change in vision, pain, redness or irritation and call immediately or proceed to the emergency department. 1 yr mrx, iop, hvf, LOCATION, oct and dp letter to pcp: dr. PERSON scribing for dr. Person i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "31 y.o. male is a glaucoma suspect due to increased c:d ratio. His intraocular pressure is controlled, goal 21 or less. Family history positive for glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08491",
"image_path": "slo_fundus_08491.jpg",
"filename": "data_08491.npz",
"report": "The patient has a history of left eye trauma and open angles in both eyes. They have primary open angle glaucoma/suspected mild glaucoma in the right eye but no need for glaucoma drops. Also, they have dry eyes and mild cataracts in both eyes.",
"age": 64.67,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "humphrey visual field mostly normal both eyes. patient also has a history of left eye trauma with angle recession. angles are open in both eyes. plan: # primary open angle glaucoma versus suspect, mild, right eye - intraocular pressure acceptable s/p selective laser trabeculoplasty both eyes - testing normal and stable both eyes DATE_TIME - no glaucoma drops for now - recommended at's for dry eyes # cataract, both eyes - mild, not visually significant, monitor return to clinic in DATE_TIME for optical coherence tomography both eyes i, PERSON, am acting as scribe for PERSONmd, PERSON for patient PERSON on DATE_TIME. - Person i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "The patient has a history of left eye trauma and open angles in both eyes. They have primary open angle glaucoma/suspected mild glaucoma in the right eye but no need for glaucoma drops. Also, they have dry eyes and mild cataracts in both eyes.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08497",
"image_path": "slo_fundus_08497.jpg",
"filename": "data_08497.npz",
"report": "The patient has posterior vitreous detachment in both eyes and is off glaucoma medications but under close monitoring. Also, the goal intraocular pressure is \u2264 17 mmHg for both eyes.",
"age": 75.68,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "bul -follow-up with dr. PERSON for eyelid care. 5. posterior vitreous detachment, both eyes -retinal detachment precautions were reviewed with the patient. 6. social/systemic issues: prior patient of dr. PERSON's. she was a former member of the lion's vision center. attending's plan: -goal intraocular pressure less than or equal to 17 mmhg, right eye. -goal intraocular pressure less than or equal to 17 mmhg, left eye. -iop *** goal od and *** goal os on DATE_TIME off glaucoma medications. -continue close monitoring off glaucoma medications. -preservative-free artificial tears as needed. -long discussion with patient on DATE_TIME and DATE_TIME: patient is symptomatic from cataracts, so we proceeded with phaco/pciol od first on DATE_TIME. -long discussion with patient on DATE_TIME: given great result so far od, we proceeded with phaco/pciol os on DATE_TIME. -i referred to oculoplastics for blepharoplasty evaluation on DATE_TIME => patient has an appointment with dr. PERSON on DATE_TIME. -follow-up with dr. PERSON for eyelid care. -rtc in DATE_TIME with iop check, hvf, dilation, and oct rnfl/gcc ou, sooner prn. the information above was documented by Person as a scribe for PERSON on DATE_TIME. i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate. i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow (neal patel, PERSON. i have reviewed the resident/fellow's notes and made any necessary changes.",
"gpt4_summary": "The patient has posterior vitreous detachment in both eyes and is off glaucoma medications but under close monitoring. Also, the goal intraocular pressure is \u2264 17 mmHg for both eyes.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08498",
"image_path": "slo_fundus_08498.jpg",
"filename": "data_08498.npz",
"report": "The patient has glaucoma with elevated intraocular pressure (IOP). They underwent laser peripheral iridotomy (LPI) in both eyes due to obstructive condition and narrow angles. They are currently on medication including dorzolamide, valtrex, and rhopressa.",
"age": 61.86,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "lpi ou. -continue dorzolamide bid ou. -continue pf qd od => to be managed by dr. PERSON. -continue valtrex 500 mg po qd. -continue rhopressa qhs od. -emphasized adherence to medication regimen. -instructions written/typed/printed out for patient (see table/details under patient instructions) previously. -preservative-free artificial tears as needed. -follow-up with dr. PERSON for cornea care. -long discussion with patient on DATE_TIME: given elevated iop od on 2 agents for iop control od and occludable PERSON, we proceeded with urgent lpi od on DATE_TIME. -long discussion with patient on DATE_TIME: given good result od s/p lpi od as well as narrow angle os, we proceeded with lpi os on DATE_TIME. -rtc in DATE_TIME with iop check, dilation, and oct rnfl/gcc ou, sooner prn. once stable from hzo standpoint, i may proceed with phaco/kdb od. we'll see. the information above was documented by Person as a scribe for PERSON on DATE_TIME. i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "The patient has glaucoma with elevated intraocular pressure (IOP). They underwent laser peripheral iridotomy (LPI) in both eyes due to obstructive condition and narrow angles. They are currently on medication including dorzolamide, valtrex, and rhopressa.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08499",
"image_path": "slo_fundus_08499.jpg",
"filename": "data_08499.npz",
"report": "The clinical note mentions a concern regarding a skull base repair. It does not mention the presence of glaucoma. The patient was requested to schedule follow-ups and ask any questions.",
"age": 46.94,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "concerns for the skull base repair. i asked him to schedule a follow up with dr. PERSON. i asked him to schedule a follow up with me in DATE_TIME. i asked him to call with any questions or concerns in the interim. all questions and concerns were answered. i personally saw and evaluated the patient with PERSON, pa-c. i performed the history, examination, nasal endoscopy and impression and plan myself. i personally made all medical and surgical diagnoses and decisions for the patient. i have reviewed the note in it's entirety and composed/edited before signing. PERSON t gray, PERSON of rhinology department of otolaryngology LOCATION cc: PERSON, PERSON, PERSON, md",
"gpt4_summary": "The clinical note mentions a concern regarding a skull base repair. It does not mention the presence of glaucoma. The patient was requested to schedule follow-ups and ask any questions.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08508",
"image_path": "slo_fundus_08508.jpg",
"filename": "data_08508.npz",
"report": "The patient has open angle glaucoma with high risk in both eyes due to ocular hypertension. They\u2019ve started on latanoprost, dorzolamide, and brimonidine medications. The left eye has retinal nerve fiber layer consistent with vein occlusion.",
"age": 72.12,
"gender": "male",
"race": "white",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "married or partnered",
"note": "problem list items addressed this visit eye/vision problems open angle with borderline findings and high glaucoma risk in both eyes overview open angle glaucoma suspect based on ocular hypertension to 40's target iop: / ; tmax: ( ) / ( ); central corneal thickness: 587 / 585; ch: / refractive error: od . x / os . x optic nerve structure and function: normal retinal nerve fiber layer and visual field right eye, consistent with vein occlusion left eye (DATE_TIME) medications and intolerances: started on latanoprost, dorzolamide, brimonidine DATE_TIME (Institution ed). procedures and complications: none relevant history and problems: central retinal vein occlusion? left eye DATE_TIME (see Institution ed) current assessment & plan continue dorzolamide ou bid, latanoprost ou qhs, stop brimonidine ou bid, relevant medications dorzolamide (trusopt) 2 % ophthalmic solution latanoprost (xalatan) 0.005 % ophthalmic solution other relevant orders automated visual field, extended - ou - both eyes (completed) oct, optic nerve - ou - both eyes - cirrus; macula cube, onh cube (completed) return DATE_TIME, for dilation.",
"gpt4_summary": "The patient has open angle glaucoma with high risk in both eyes due to ocular hypertension. They\u2019ve started on latanoprost, dorzolamide, and brimonidine medications. The left eye has retinal nerve fiber layer consistent with vein occlusion.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08514",
"image_path": "slo_fundus_08514.jpg",
"filename": "data_08514.npz",
"report": "70yo female using high-risk drug ethambutol for lung disease, has scattered defects in left eye but normal color vision. Not confirmed glaucoma. Also has vitreous detachment, dry eyes, reduced vision, and nuclear sclerosis.",
"age": 70.62,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "70 yo female presents for follow up in the setting of using new high-risk medication - ethambutol for PERSON lung disease. \u00ff 1. h/o ethambutol use 2' to mac lung disease -duration: started DATE_TIME, discontinued DATE_TIME: 400 mg po tid (21 mg/kg) -was also on rifampin 300 mg po bid and azithromycin 500 mg po qd -color vision normal ou, h/o full amsler ou -hvf DATE_TIME - od essentially full, good reliability - os few scattered defects with one repeatable defect nasal to blindspot, good reliability -rnfl DATE_TIME normal ou -baseline fundus photos taken DATE_TIME \u00ff 2. posterior vitreous detachment ou -rd precautions \u00ff 3. dry eyes ou -continue with warm compresses bid and at's DATE_TIME \u00ff 4. PERSON reduced bcva 20/70, denies diplopia -patched as a child, h/o strabismus surgery -monocular precautions, polycarbonate material for spectacles \u00ff 5. nuclear sclerosis ou -not visually significant -asymptomatic -observe rtc DATE_TIME for cee i have reviewed the notes, assessments, and/or procedures performed by dr. PERSON (PERSON resident), have made appropriate changes as needed, and i agree with his documentation above.",
"gpt4_summary": "70yo female using high-risk drug ethambutol for lung disease, has scattered defects in left eye but normal color vision. Not confirmed glaucoma. Also has vitreous detachment, dry eyes, reduced vision, and nuclear sclerosis.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08520",
"image_path": "slo_fundus_08520.jpg",
"filename": "data_08520.npz",
"report": "Patient has visual suppression of the vestibular-ocular reflex and past hypertropia. Recommended follow-up with neuro-ophthalmology, optometry, and neurology; glasses refraction and fresnel prism. No mention of glaucoma.",
"age": 34.89,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "visual suppression of the vestibular-ocular reflex, ? relevance to #1 4. prior left hypertropia not seen DATE_TIME recommendations: 1. follow-up with neuro-ophthalmology in DATE_TIME, sooner prn 2. referral to optometry for a refraction and glasses 3. fresnel prism (1 bd os) in the lower portion of the glasses 4. re-establish care with neurology 1. oct optic nerves ou and macula with retinal ganglion cell / inner plexiform segmentation DATE_TIME. follow-up with neuro-ophthalmology in DATE_TIME, sooner prn 3. follow-up with neurology and rheumatology as scheduled 4. agree with repeating mri brain with and without contrast in DATE_TIME (this note was prepared at least in part by PERSON, neuro-ophthalmology fellow)",
"gpt4_summary": "Patient has visual suppression of the vestibular-ocular reflex and past hypertropia. Recommended follow-up with neuro-ophthalmology, optometry, and neurology; glasses refraction and fresnel prism. No mention of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08521",
"image_path": "slo_fundus_08521.jpg",
"filename": "data_08521.npz",
"report": "The patient has glaucoma worsening at normal intraocular pressures. Multiple follow-ups are planned with specialists. They have been given medication plans including Vyzulta and Doxycycline to manage the condition.",
"age": 93.21,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "seen by dr. PERSON at bpei naples (he was my cornea co-fellow at bpei miami). patient was also seen by dr. PERSON (one of my attendings at bpei) on DATE_TIME and then again in DATE_TIME. attending's plan: -goal intraocular pressure less than or equal to 12 mmhg, right eye. -goal intraocular pressure less than or equal to 12 mmhg, left eye. -iop at goal od and at goal os on DATE_TIME on pf cosopt tid ou, PERSON, and lotemax qd od. -continue vyzulta qhs ou. -continue pf PERSON => samples given on DATE_TIME. -continue lotemax qd od => to be managed by cornea team. -continue doxycycline 50 mg po qd => to be managed by cornea team. -instructions written out for patient (see table/details under patient instructions) previously. -emphasized adherence to medication regimen. -continue valtrex 1000 mg po qd => to be managed by cornea team. -continue NRP per retina/dr. PERSON. -follow-up with low-vision as planned. -follow-up with dr. PERSON for cornea care => ok to proceed with calcium deposit removal if needed. -follow-up with retina specialist for care. -follow-up with retina as planned. -note to cardiologist (PERSON) and pcp on DATE_TIME: given worsening of glaucoma at normal intraocular pressures (although borderline), i would recommend ruling out nocturnal hypotension (using bp medications in the am, if possible) and ruling out sleep apnea if any signs/symptoms as these two diagnoses could cause glaucoma to worsen at normal iops. -rtc in DATE_TIME with iop check ou, dilation ou, oct rnfl/gcc od (experienced technician), and disc photos ou, sooner prn. if hvfs worsen further, strongly consider cpc versus bgi. the information above was documented by Person as a scribe for PERSON on DATE_TIME.",
"gpt4_summary": "The patient has glaucoma worsening at normal intraocular pressures. Multiple follow-ups are planned with specialists. They have been given medication plans including Vyzulta and Doxycycline to manage the condition.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08522",
"image_path": "slo_fundus_08522.jpg",
"filename": "data_08522.npz",
"report": "77 y.o. white, non-hispanic male diagnosed with glaucoma. Had nose carcinoma previously treated by resection & radiation. No radiation retinopathy found.",
"age": 77.02,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "a 77 y.o. white, non-hispanic male was evaluated and diagnosed with glaucoma. carcinoma on nose s/p resection and radiation -no radiation retinopathy on dfe DATE_TIME -continue to monitor",
"gpt4_summary": "77 y.o. white, non-hispanic male diagnosed with glaucoma. Had nose carcinoma previously treated by resection & radiation. No radiation retinopathy found.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08523",
"image_path": "slo_fundus_08523.jpg",
"filename": "data_08523.npz",
"report": "The 52-year-old male patient has a family history of glaucoma, and shows signs of primary open-angle glaucoma (poag) with increased c:d ou. His intraocular pressure (IOP) is stable, and he shows mild visual field defects. Repeat visual field test recommended.",
"age": 52.28,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "52 y.o. male 1. poag(s) based on increased c:d ou fhx positive (mother had surgery) tmax unknown cct 525/514 (thin ou) hvf od reliable, mild ins/sns defects at far nasal edge of test, new os reliable and full repeat hvf next time oct borderline os, PERSON, stable rnfl thickness average ou dp stable gonio open ou iop controlled observe 2. s/PERSON 2003 (h/o -2.25 myope prior to surgery) observe DATE_TIME/o viral conjunctivitis quiet DATE_TIME, observe 4. refractive error: a prescription for new glasses was given to the patient DATE_TIME, may also cpm with otc readers +1.75 5. posterior vitreous detachment ou: no retinal holes, tears, or detachment on exam. retinal detachment precautions were reviewed with the patient. 6 mo check va, iop and hvf ou",
"gpt4_summary": "The 52-year-old male patient has a family history of glaucoma, and shows signs of primary open-angle glaucoma (poag) with increased c:d ou. His intraocular pressure (IOP) is stable, and he shows mild visual field defects. Repeat visual field test recommended.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08525",
"image_path": "slo_fundus_08525.jpg",
"filename": "data_08525.npz",
"report": "The patient is taking several medications for various conditions including severe constipation, hypertension, back pain, and arthritis among others. There is no mention of glaucoma.",
"age": 65.08,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "polyethylene glycol (glycolax) 17 gram packet (taking) take 17 g by mouth DATE_TIME as needed (severe constipation). protein powder (LOCATION) powd (taking) take by mouth 3 (three) times a day with meals. senna (senokot) 8.6 mg tablet (taking) take 1 tablet by mouth 2 (two) times a day as needed for constipation. tizanidine (zanaflex) 2 mg tablet (taking) 4mg in the am, DATE_TIME in the afternoon, 4mg in the pm acetaminophen (tylenol) 325 mg tablet take 2 tablets (650 mg total) by mouth every 6 (DATE_TIME. PERSON (lopressor) 25 mg tablet take 0.5 tablets (12.5 mg total) by mouth 2 (two) times a day. your orders normal orders this visit humphrey visual field - ou - both eyes oct, optic nerve - ou - both eyes - cirrus condition list as of DATE_TIME tinnitus cystocele osteoporosis aortic valve regurgitation hypothyroidism sicca syndrome iron deficiency anemia pharyngitis urinary incontinence blood in urine kidney stone osteoarthritis of knee rheumatoid arthritis streptococcal sore throat heterozygous thalassemia decubitus ulcer of left buttock, stage 4 history of total hip replacement total knee replacement status pericarditis constipation sacral osteomyelitis microcytic anemia hypertension back pain of lumbosacaral region with sciatica results summary immunizations administered on date of encounter - DATE_TIME none",
"gpt4_summary": "The patient is taking several medications for various conditions including severe constipation, hypertension, back pain, and arthritis among others. There is no mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08529",
"image_path": "slo_fundus_08529.jpg",
"filename": "data_08529.npz",
"report": "84 y.o. male with hypertension, CAD, and hyperlipidemia. Comprehensive eye exam revealed cataracts, myopic shift, and posterior vitreous detachment. Enlarged c/d ratio, IOP WNL. No glaucoma.",
"age": 84.96,
"gender": "male",
"race": "white",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "married or partnered",
"note": "84 y.o. male with hypertension, cad, hyperlipidemia, here for comprehensive eye exam # cataracts, ou - bat 20/50, 20/50 - borderline significant, myopic shift. pt still not bothered. - poor dilation, on flomax > observe # posterior vitreous detachment, ou - rd precautions reviewed # enlarged c/d ratio - no trauma, no steroid use - iop wnl - no family hx - cct DATE_TIME wnl ou DATE_TIME wnl ou, stable DATE_TIME od wnl os borderline thin temp, overall stable DATE_TIME od wnl, os borderline thin overall stable - hvf DATE_TIME borderline unreliable od inferior nasal step os ? rim artifact hvf DATE_TIME: od with improved inferior nasal step, os with nonspecific inferior defects hvf DATE_TIME od nonspecific inferior defects os ?rim artifact, nonspecific nasal defects hvf DATE_TIME od 20%fn increased inferior and superior nonspecific defects os high fl increased nonspecific defect > stable. observe # s/p ptosis repair DATE_TIME # choroidal nevus os - stable in size - no orange pigment or subretinal fluid - observe # eyelid lesion lul - looks crusted and dry - can try moisturizer. if worse, patient knows to inform his dermatologist. #blepharitis ou - discusses ats, lid hygiene, and warm compresses fu DATE_TIME, mrx, hvf, oct, dilate i saw and evaluated this patient and discussed the case as appropriate with the resident. i have reviewed the resident's notes and made any necessary changes. PERSON",
"gpt4_summary": "84 y.o. male with hypertension, CAD, and hyperlipidemia. Comprehensive eye exam revealed cataracts, myopic shift, and posterior vitreous detachment. Enlarged c/d ratio, IOP WNL. No glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08530",
"image_path": "slo_fundus_08530.jpg",
"filename": "data_08530.npz",
"report": "Patient has early cataract in both eyes, partial vitreous detachment in left eye, and greater optic disc cupping in right eye indicating suspected glaucoma. No eye pressure elevation; normal OCT.",
"age": 69.98,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "imp: early cataract ou pvd os cupping od>os (gl-s; +fh) no iop elevation; normal oct of rnfl ou now; PERSON refr error plan: rx=m yrly",
"gpt4_summary": "Patient has early cataract in both eyes, partial vitreous detachment in left eye, and greater optic disc cupping in right eye indicating suspected glaucoma. No eye pressure elevation; normal OCT.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08531",
"image_path": "slo_fundus_08531.jpg",
"filename": "data_08531.npz",
"report": "Patient post-phaco/iol surgery in left eye, has cataract in right eye with 20/25+ vision. No glaucoma detected, normal HVF & OCT. Experiences dry eye symptoms more in left eye. Plan to monitor right eye cataract.",
"age": 78.46,
"gender": "female",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "married or partnered",
"note": "# s/p phaco/iol os # cataract od - bcva 20/25+, no symptomatic progression # large c/d ratio --normal hvf and oct today # dry eye os>od - spk with dry eye symptoms #refr error plan: - ats - observe cataract od for now - mrx provided rtc 6-12 months, sooner prn PERSON, pgy-2 re-check hvf and oct of rnfl then",
"gpt4_summary": "Patient post-phaco/iol surgery in left eye, has cataract in right eye with 20/25+ vision. No glaucoma detected, normal HVF & OCT. Experiences dry eye symptoms more in left eye. Plan to monitor right eye cataract.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08542",
"image_path": "slo_fundus_08542.jpg",
"filename": "data_08542.npz",
"report": "The 89-year-old female patient has elevated intraocular pressure in left eye and thin optical coherence tomography. She's on Travatan for potential glaucoma and is referred to a glaucoma specialist. Also has cataracts.",
"age": 89.35,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "PERSON is a 89 y.o. female pxfg risks include race, pxf, age iop is wnl od, elevated os, tcorr is +2 ou . oct rnfl thin ou. hvf: sas ou gonio: open angles, not acludable 1-2 pigmented tm ou.. safe to dilate patient on travatan qhs ou refer to glaucoma specialist cataract w/ pxf ou try new rx continue to observe. follow up with glaucoma team next available by signing my name below, i, PERSON, acting as a scribe, attest that this documentation has been prepared under the direction and in the presence of PERSON, LOCATION DATE_TIME DATE_TIME by signing my name below, i, PERSON, attest that this documentation has been prepared under my direction.",
"gpt4_summary": "The 89-year-old female patient has elevated intraocular pressure in left eye and thin optical coherence tomography. She's on Travatan for potential glaucoma and is referred to a glaucoma specialist. Also has cataracts.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08546",
"image_path": "slo_fundus_08546.jpg",
"filename": "data_08546.npz",
"report": "Gertrude Gallagher, 78 years old, has been diagnosed as a glaucoma suspect due to increased cup/disc ratio in both eyes. She also has cataract in both eyes and dermatochalasis. Her blood glucose and pressure are being controlled.",
"age": 78.07,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "DATE_TIME PERSON, patient: gertrude f PERSON mr number: NUMBER date of birth: DATE_TIME date of visit: DATE_TIME dear dr. PERSON: i saw our mutual patient, gertrude gallagher, for a follow-up eye examination. please find below a summary of the examination, assessment, and plan. thank you for allowing me to participate in this patient's care. vision readings for this visit: va distance LOCATION distance cc va near LOCATION near cc iop right 20/30 19 left 20/30+2 19 assessment and plan: 78 f hx htn, dm last visit here with me in DATE_TIME. endocrinologist is PERSON md . # no evidence of diabetic retinopathy. - importance of blood glucose and blood pressure control discussed with patient. - annual dilated eye exams, sooner prn visual changes. # glaucoma suspect with increased cup/disc ratio, both eyes [ fhx: father [ cct: 564,567 [ gonio: open to cbb 360 ou [ oct DATE_TIME: wnl ou [ hvf DATE_TIME: nonspecific inf defect od, full os - no intervention required at this time. continue to monitor. # cataract, both eyes, not yet visually significant to warrant surgery. - monitor for now. # dermatochalasis, both upper eyelids, not functionally bothering the patient at this time. - monitor. # refractive error, some change vs previous, would like to change glasses. rtc 1 year, sooner prn if you have questions, please do not hesitate to call me. i look forward to following gertrude along with you. sincerely, , LOCATION PERSON, md",
"gpt4_summary": "Gertrude Gallagher, 78 years old, has been diagnosed as a glaucoma suspect due to increased cup/disc ratio in both eyes. She also has cataract in both eyes and dermatochalasis. Her blood glucose and pressure are being controlled.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08552",
"image_path": "slo_fundus_08552.jpg",
"filename": "data_08552.npz",
"report": "79 yo woman with history of hyperlipidemia, hypothyroidism and non-ischemic cardiomyopathy undergoes eye surgery. Has mild pco, oily tear film and increased c/d, but no glaucoma.",
"age": 79.68,
"gender": "female",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "79 yo woman with history of hyperlipidemia, hypothyroidism, non-ischemic cardiomyopathy daughter is PERSON radiologist, pari pandharipande, cell PHONE_NUMBER. pt lives in champagne, LOCATION. \u00ff\u00ff 1. s/p phaco/pciol ou (od DATE_TIME and os DATE_TIME) -comfortable, happy -mild pco od, LOCATION >> mrx provided as backup DATE_TIME (only uses readers and happy with current) \u00ff\u00ff 2. mgd ou with oily tear film - using refresh bid - using warm compresses >> continue warm compresses at least qhs, at prn, oily fish, she feels this is helping \u00ff\u00ff 3. incr'd c/d ou tmax 20/19. cct 504/523 (thin). no fhx glaucoma hvf DATE_TIME: good reliability, full ou hvf DATE_TIME: overall full; few spots of decreased sensitivity nasally os 1st hvf DATE_TIME: od high fixation losses. ?sns, LOCATION. os fixation losses and false +. full DATE_TIME: wnl ou, similar to DATE_TIME oct DATE_TIME: wnl ou; gc shows mild LOCATION loss. will monitor. DATE_TIME: wnl ou oct DATE_TIME: wnl ou oct DATE_TIME: wnl ou oct DATE_TIME: wnl ou >> will follow \u00ff\u00ff 4. small choroidal nevus os -benign features \u00ff\u00ff 5. pvd ou -no tears, breaks -rd precautions",
"gpt4_summary": "79 yo woman with history of hyperlipidemia, hypothyroidism and non-ischemic cardiomyopathy undergoes eye surgery. Has mild pco, oily tear film and increased c/d, but no glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08554",
"image_path": "slo_fundus_08554.jpg",
"filename": "data_08554.npz",
"report": "Mid-teens patient being monitored for glaucoma. On Latanoprost and Timolol. Cataract is mild but causing symptoms, especially in left eye. Had trabeculectomy/mmc in right eye. Intraocular pressure stable in both eyes.",
"age": 69.65,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "mid-teens. DATE_TIME much higher at 25 both eyes on latanoprost and timolol. nerves are small and slightly pale. cataract is mild and she is quite symptomatic with everything seeming gray, especially in the left eye also has lattice going to see PERSON. monitored for glaucoma for many from rockwood DATE_TIME: hvf DATE_TIME DATE_TIME od: sup arcuate, new. os: borderline reliability, early sup ns, similar to previous plan: # primary open angle glaucoma, both eyes - doing well s/p trabeculectomy/mmc right eye - intraocular pressure was good left eye initially but was creeping back up (all sutures lysed), so timolol was started - intraocular pressure now doing well both eyes - continue timolol once DATE_TIME left eye # foreign body sensation, right eye - limbal conjunctival suture protruding in the right eye, removed DATE_TIME # cataract, both eyes - mild, not visually significant, monitor return to clinic DATE_TIME, i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "Mid-teens patient being monitored for glaucoma. On Latanoprost and Timolol. Cataract is mild but causing symptoms, especially in left eye. Had trabeculectomy/mmc in right eye. Intraocular pressure stable in both eyes.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08557",
"image_path": "slo_fundus_08557.jpg",
"filename": "data_08557.npz",
"report": "Patient had normal opening pressure in recent lp. Has choroidal plexus carcinoma, now on chemo, and left homonymous hemianopia. Exhibits papilledema and left complete third cranial nerve palsy. No mention of glaucoma.",
"age": 12.95,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "recent lp (12/08) revealed a normal opening pressure (17 cmh2o) and that she is not currently having any symptoms of increased intracranial pressure. we will plan to continue monitoring her closely, with repeat visual field testing within DATE_TIME. impression: 1. choroidal plexus carcinoma s/p surgical resection, now on chemotherapy ?2. left homonymous hemianopia secondary to 1 3. papilledema, in the setting of 1 4. enhancing lesion involving the left oculomotor nerve and posterior cavernous sinus. 5. left complete third cranial nerve palsy with pupil involvement secondary to #4 recommendations: 1. follow-up with neuro-ophthalmology within DATE_TIME. a card was given to the father with our contact information - he will call back when they have a date for the next cycle of chemo and will be returning to LOCATION (excepted DATE_TIME) 2. please contact neuro-ophthalmology on call if you have any questions or concers this note was prepared with the assistance of ines lains, PERSON, neuro-ophthalmology resident. it is a pleasure to participate in the care of this patient. please do not hesitate to call with questions. ? sincerely, PERSON, PERSON spent DATE_TIME with this patient, more than 50% of which was face to face with the patient.",
"gpt4_summary": "Patient had normal opening pressure in recent lp. Has choroidal plexus carcinoma, now on chemo, and left homonymous hemianopia. Exhibits papilledema and left complete third cranial nerve palsy. No mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08564",
"image_path": "slo_fundus_08564.jpg",
"filename": "data_08564.npz",
"report": "66 y.o. had right v1 zoster with postherpetic neuralgia, treated with valtrex. No corneal or retinal involvement. Prior complex cataract surgery, had infection. Now glaucoma suspect; switched from timolol to latanoprost, with improved intraocular pressure.",
"age": 66.96,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "66 y.o. here with his daugther ew fu for zoster \u00ff #right v1 zoster, resolved with postherpetic neuralgia ?-started on valtrex 1g tid DATE_TIME by his pcp - no evidence of corneal involvement or retinal involvement. - DATE_TIME: no more pain. no longer taking gabapentin or nortriptyline #s/p complex phaco/pciol with trypan os DATE_TIME , aim -10.00 - doing well, happy with vision >provided new rx #hx cataract surgery od >DATE_TIME - done in LOCATION - per patient, had an infection prior to the cataract surgery - appears to be extracapsular cataract surgery, patient states it might have been a complicated surgery and took DATE_TIME. no prior records available >monitor # glaucoma suspect ou no fhx of glaucoma iop normal cct 535/548 oct rnfl DATE_TIME: PERSON thin sup and inf DATE_TIME 86/64 od wnl os thin sup and PERSON hvf DATE_TIME field): od: generalized depression. ?enlarged blindspot with scattered central losses os: nasal losses not fully respecting vertical meridian- ?enlarged blind spot vs early sup arcuate vs sup rim losses DATE_TIME od enlarged blind spot os early sup arcuate DATE_TIME: iop suboptimal on timolol, no significant iop reduction, switch to latanoprost qhs os DATE_TIME: iop suboptimal on latanoprost qhs os DATE_TIME: iop 16/16 off latanoprost x DATE_TIME. restart latanoprost. fu DATE_TIME, hvf/oct. DATE_TIME: iop much better on latanoprost ou, continue # posterior vitreous detachment os - notes increased floaters x DATE_TIME breaks / detachments > retinal detachment precautions DATE_TIME, iop check",
"gpt4_summary": "66 y.o. had right v1 zoster with postherpetic neuralgia, treated with valtrex. No corneal or retinal involvement. Prior complex cataract surgery, had infection. Now glaucoma suspect; switched from timolol to latanoprost, with improved intraocular pressure.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08565",
"image_path": "slo_fundus_08565.jpg",
"filename": "data_08565.npz",
"report": "The note suggests a likely left optic neuropathy, with potential causes including traumatic optic neuropathy or a compressive cause. No specific mention of glaucoma. MRI recommended.",
"age": 71.03,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "generalized depression. oct, optic nerve - ou - both eyes - cirrus; optic disc; gcc, rnfl right eye reliability was good. left eye reliability was good. notes od: normal prnfl thickness (avg 100 microns). normal macular gcipl (avg 75 microns) os: thinner prnfl compared with od (avg 87 microns). macular gcipl thinning (avg 64 microns). ? impression: mr. PERSON likely has a left optic neuropathy based upon the left relative apd, mild visual field depression os, and oct showing PERSON and macular gcl thinning compared to the right eye. the cause could be a traumatic optic neuropathy from history of facial trauma from a hockey puck, but we ordered an mri of the orbits with and without contrast to exclude a compressive cause. we discussed this assessment and recommendation in detail. ?recommendations: 1. mri orbits with and without contrast 2. return on DATE_TIME as mri within DATE_TIME ? PERSON, LOCATION note: greater than half of this DATE_TIME visit was spent counseling the patient on the medical condition or coordinating care.",
"gpt4_summary": "The note suggests a likely left optic neuropathy, with potential causes including traumatic optic neuropathy or a compressive cause. No specific mention of glaucoma. MRI recommended.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08566",
"image_path": "slo_fundus_08566.jpg",
"filename": "data_08566.npz",
"report": "The patient is under treatment for maintaining intraocular pressure in both eyes at 13 mmhg or less. Medications used include latanoprost and brimonidine. Consideration for future use of selective laser trabeculoplasty. Glaucoma not confirmed.",
"age": 68.4,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "dr. PERSON's at ehs. she enjoys swimming and tries to do a mile a day. attending's plan: -goal intraocular pressure less than or equal to 13 mmhg, right eye. -goal intraocular pressure less than or equal to 13 mmhg, left eye. -iop at goal od and at goal os on DATE_TIME on latanoprost qhs ou and brimonidine bid od. -continue latanoprost qhs ou. -continue brimonidine bid od. -instructions written/typed/printed out for patient (see table/details under patient instructions) previously. -emphasized adherence to medication regimen. -encouraged tight blood glucose, blood pressure and blood cholesterol control. -preservative-free artificial tears as needed. -follow-up with dr. PERSON for cornea care. -retinal detachment precautions were reviewed with the patient. -long discussion with patient on DATE_TIME: given stable hvf and oct ou as well as iops at goal ou, we will proceed with current medication regimen and schedule a DATE_TIME follow-up. -rtc in DATE_TIME with iop check, arx, bat, dilation, and disc photos ou, sooner prn. we could consider slt in future although i tend to think slt isn't as effective in ntg. we could also consider phaco/migs (?peck) when cataracts become visually-significant. the information above was documented by Person as a scribe for PERSON on DATE_TIME. i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "The patient is under treatment for maintaining intraocular pressure in both eyes at 13 mmhg or less. Medications used include latanoprost and brimonidine. Consideration for future use of selective laser trabeculoplasty. Glaucoma not confirmed.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08567",
"image_path": "slo_fundus_08567.jpg",
"filename": "data_08567.npz",
"report": "Female patient presents for follow-up of type II diabetes, mild cataract, cornea guttata, and is a glaucoma suspect. No evidence of diabetic retinopathy. Stable glaucoma suspect based on corneal asymmetry.\n",
"age": 62.98,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "DATE_TIME. female presents for follow-up of dm ii, early cataract, cornea guttata, glaucoma suspect 1. diabetes mellitus, type ii - no evidence of diabetic retinopathy on dilated macular examination DATE_TIME a1c: 7.3% DATE_TIME - recommend DATE_TIME dilated eye exams. - discussed importance of blood sugar control. - patient was advised to maintain tight blood sugar and blood pressure control in order to reduce risk of complications in eyes, kidneys, and peripheral nerves to hands/feet/etc 2. cataract, not visually significant - mild cataract is present that is not visually significant. - bcva od 20/20, os 20/20 - observation at this time was recommended. 3. PERSON guttae ou but no haze/edema - cct in PHONE_NUMBER - cct in PHONE_NUMBER - stable - cct DATE_TIME 604/548 - bcva 20/20 ou - no complaints of morning blurred vision - observe 4. glaucoma suspect - glaucoma suspect based on c/d asymmetry os > od - iop - 14/14 - tmax - 15/15 - cct - 566/574 (with corneal edema) - c/d - 0.35/0.5 - gonio - open ou - c25s/trptm, no pas od, c30r, tr ptm, no pas DATE_TIME - family history - mother + - hvf DATE_TIME: full ou - hvf DATE_TIME: full ou - oct rnfl DATE_TIME: PERSON oct rnfl DATE_TIME wnl ou - fundus photos obtained - DATE_TIME - dilated optic nerve exam performed ou DATE_TIME - discussed potential for progressive irreversible vision loss due to glaucomatous optic neuropathy. - likely physiologic cupping os due to larger nerve - follow as suspect rtc DATE_TIME or sooner prn with LOCATION, hvf 24-2, cct h nguyen pgy-4",
"gpt4_summary": "Female patient presents for follow-up of type II diabetes, mild cataract, cornea guttata, and is a glaucoma suspect. No evidence of diabetic retinopathy. Stable glaucoma suspect based on corneal asymmetry.\n",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08569",
"image_path": "slo_fundus_08569.jpg",
"filename": "data_08569.npz",
"report": "Patient with Susac syndrome, stable, not immunosuppressed. Risk of seizures, on Trileptal. Intraocular pressure exceeds goal in both eyes, off glaucoma meds. Discussed adherence to meds.",
"age": 31.95,
"gender": "female",
"race": "white",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "single",
"note": "spells. her susac syndrome was thought to be relatively stable, so immunosuppression was not initiated during her hospitalization and referral to neuro-immunology was made. she was started on trileptal for abnormal eeg activity with risk for seizures but of uncertain clinical significance. previously seen by dr. PERSON at Institution and also at ocb. she lives DATE_TIME away on the cape. attending's plan: -goal intraocular pressure less than or equal to 12 mmhg, right eye. -goal intraocular pressure less than or equal to 12 mmhg, left eye. -iop above goal od and above goal os on DATE_TIME off glaucoma medications. -start PERSON given cupping/thinning on oct/hvf deficits. -emphasized adherence to medication regimen. -instructions written/typed/printed out for patient (see table/details under patient instructions). -preservative-free artificial tears as needed. -long discussion with patient on DATE_TIME: incredibly strong blink reflex. we will trial gonioscopy/pachymetry in future (once she trusts us). i felt strongly about starting eye drops given cupping/thin oct/hvf deficits even though they may be related to LOCATION. -rtc in DATE_TIME with iop check (with icare), pachymetry, gonioscopy, and disc photos ou, sooner prn. i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow (PERSON, PERSON. i have reviewed the resident/fellow's notes and made any necessary changes.",
"gpt4_summary": "Patient with Susac syndrome, stable, not immunosuppressed. Risk of seizures, on Trileptal. Intraocular pressure exceeds goal in both eyes, off glaucoma meds. Discussed adherence to meds.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08570",
"image_path": "slo_fundus_08570.jpg",
"filename": "data_08570.npz",
"report": "The patient has giant cell arteritis, not glaucoma. The right eye is stable while there's a segmentation error in the left eye's ganglion cell complex measurement. The doctor plans steroid treatment and recommended vaccinations.",
"age": 78.89,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "and stable in the right eye (80 microns DATE_TIME, 79 microns on DATE_TIME). there was a segmentation error in the ganglion cell complex measurement in the left eye. my overall impression is that this patient has giant cell arteritis. my plan is: -follow up chest magnetic resonance angiography to assess for aneurysm -follow up: anca, hcv, hbv, spep, crp, esr, cbc, bmp, PERSON -consider actemra -i recommend the following steroid taper: 40 mg po prednisone for DATE_TIME, then 30 mg for DATE_TIME, then 20 mg for DATE_TIME, then 10 mg until follow up wutg dr. PERSON -recommend the covid boosters, influenza vaccination, shingles vaccination, tetanus-diphtheria vaccination, and pneumonia vaccination. follow up with primary care doctor to make sure she is up to date with the immunizations. we discussed this diagnostic impression and plan in detail. i will see the patient again in DATE_TIME to reassess progress, sooner if new symptoms arise in the interim. thank you for allowing me to participate in the care of your patient. ???? ??please do not hesitate to call with questions. ? sincerely, ? PERSON, LOCATION neuro-ophthalmology, headache unit, and skull base neurology clinic. division of neuroimmunology, Institution neuro-ophthalmology, Institution this note was prepared with the assistance of LOCATION stevanovic LOCATION, pgy-3 ophthalmology resident ? note: i personally spent {encounter time:19197::'15','25','30','40','45','60','80','100'} minutes preparing for, caring for the patient (face-to-face and non-face-to-face), and finalizing the visit for this patient. this time excludes any listed procedures.",
"gpt4_summary": "The patient has giant cell arteritis, not glaucoma. The right eye is stable while there's a segmentation error in the left eye's ganglion cell complex measurement. The doctor plans steroid treatment and recommended vaccinations.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08572",
"image_path": "slo_fundus_08572.jpg",
"filename": "data_08572.npz",
"report": "Patient, diagnosed with ocular hypertension both eyes, exhibits intraocular pressure of 38 (right eye) and 44 (left eye). Central corneal thickness is 537 (right) and 584 (left). Left eye shows early glaucoma damage. New plan includes latanoprost and cosopt. Family history of glaucoma.",
"age": 45.28,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "first seen by PERSON PERSON on 01/14//2021 diagnosis: ocular hypertension both eyes (last seen by dr. hoguet in DATE_TIME) target iop: / , tmax: 38 (DATE_TIME) / 44 (DATE_TIME) central corneal thickness: 537 / 584 gonioscopy: open both eyes refractive error: od -1.25 . -0.50 . 100 / os -1.75 . +0.25 . 080 optic nerve findings on initial visit right eye: normal optic nerve findings on initial visit left eye: mild thinning visual fields on initial visit right eye: normal visual fields on initial visit left eye: superior nasal step and paracentral defect medication history and intolerances at first visit: none (previously on timolol) glaucoma procedures right eye: none glaucoma procedures left eye: none other eye procedures right eye: none other eye procedures left eye: none other eye problems right eye: none other eye problems left eye: none family history: yes (mother and maternal uncle are df patients, mother undergoing surgery; maternal grandmother went blind from glaucoma) steroids: no trauma: no asthma: no other medical history and problems: hypothyroid, anemia, anxiety initial note: history of ocular htn, stopped drops in DATE_TIME. PERSON. presented with intraocular pressure 38 right eye and DATE_TIME left eye off treatment. central corneal thickness 537 right eye and 584 left eye. right eye with no evidence glaucoma damage, left eye with early damage with sn step. initiated cosopt and ltn. plan: intraocular pressure too high both eyes DATE_TIME, improved with one round drops start latanoprost qhs and cosopt twice a day to both eyes return to clinic DATE_TIME for follow up repeat central corneal thickness given 50 micron difference",
"gpt4_summary": "Patient, diagnosed with ocular hypertension both eyes, exhibits intraocular pressure of 38 (right eye) and 44 (left eye). Central corneal thickness is 537 (right) and 584 (left). Left eye shows early glaucoma damage. New plan includes latanoprost and cosopt. Family history of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08575",
"image_path": "slo_fundus_08575.jpg",
"filename": "data_08575.npz",
"report": "The patient has a history of femoral artery synovial cell sarcoma and intracranial avm. The patient is under follow-up for glaucoma suspect testing with open angle glaucoma suspected. They also have dry eyes, MGD/blepharitis, and a refractive error.",
"age": 53.05,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "DATE_TIME f with history of r femoral artery synovial cell sarcoma s/p radiation DATE_TIME, left-sided intracranial avm s/p craniotomy in DATE_TIME presenting for follow-up for glaucoma suspect testing, previously seen at ocb: \u00ff 1. choroidal nevus od, last dilated DATE_TIME - small and flat - no drusen - likely part of normal pigmentation - fundus photos DATE_TIME - dilate at next visit. \u00ff 2. open angle glaucoma suspect - was followed at ocb - iop ok DATE_TIME - rims appear healthy - pachy thick, true iop lower - hvf (DATE_TIME) reliable, full ou. - oct rnfl (DATE_TIME) no thinning ou. 3. mgd/blepharitis - doing wc, PERSON, lid scrubs - discussed omega-3 supplements - she is asking about steroids would try fish oil, flax seed oil allergic to azithromycin could try topical lotemax gel as needed, rx given, no refills 4. dry eyes schirmer test: od 12mm, os 7mm use artificial tears (preservative -free) as needed for symptoms of dry eye episodes of recurrent erosions? try lubricating gel qhs 5. refractive error new glasses prescription given DATE_TIME follow up DATE_TIME for dilated exam PersonON, PERSON i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow. i have reviewed the resident/fellow's notes and made any necessary changes. PERSON, md, facs",
"gpt4_summary": "The patient has a history of femoral artery synovial cell sarcoma and intracranial avm. The patient is under follow-up for glaucoma suspect testing with open angle glaucoma suspected. They also have dry eyes, MGD/blepharitis, and a refractive error.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08581",
"image_path": "slo_fundus_08581.jpg",
"filename": "data_08581.npz",
"report": "Patient shows large c/d ratio; possible primary open angle glaucoma suspected. Also, hyperthyroidism and thyroid eye disease observed. Plan: start timolol gel treatments.",
"age": 42.63,
"gender": "male",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "first seen by Person on DATE_TIME. large c/d ratio noticed DATE_TIME and has since been monitored as a glaucoma suspect. first noticed left eyelid retraction DATE_TIME. found to have hyperthyroidism and thyroid eye disease. diagnosis: possible primary open angle glaucoma od, mild target iop: / , tmax: ( ) / ( ) central corneal thickness: 572 / 569 gonioscopy: open to cbb, trace pigment refractive error: od . . / os . . optic nerve/rnfl findings on initial visit right eye (DATE_TIME): 0.8, mild inferior borderline thinning optic nerve/rnfl findings on initial visit left eye (DATE_TIME): 0.8 full visual fields on initial visit right eye (DATE_TIME): full visual fields on initial visit left eye (2/203/2021): full medication history at first visit: medication intolerances: glaucoma procedures right eye: glaucoma procedures left eye: other eye procedures right eye: other eye procedures left eye: other eye problems right eye: other eye problems left eye: family history: pgm steroids: no trauma: no asthma: no other medical history and problems: hyperthyroidism assessment: 1. likely pre-perimetric primary open angle glaucoma od, suspect os -borderline inferior thinning on oct rnfl and gcc, new compared to previous; also oct suggests mild changes in vcdr, rim area all in the same eye -discussed repeat testing with observation to confirm change versus treatment -start timolol, and will reassess oct in DATE_TIME hvf ordered DATE_TIME in error 2. hyperthyroidism, mild thyroid eye disease -on methimazole -using artificial tears plan: -start timolol gel 1/0 rtc in DATE_TIME for iop check",
"gpt4_summary": "Patient shows large c/d ratio; possible primary open angle glaucoma suspected. Also, hyperthyroidism and thyroid eye disease observed. Plan: start timolol gel treatments.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08590",
"image_path": "slo_fundus_08590.jpg",
"filename": "data_08590.npz",
"report": "71 y.o. patient with history of hypercholesterolemia, hypertension, migraine, GERD, osteoporosis, presbyopia and dry eye. Recent laser retinopexy; no new breaks. Cataracts stable. No family history of glaucoma; low risk.",
"age": 71.58,
"gender": "female",
"race": "white",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "married or partnered",
"note": "71 y.o. with hx of hypercholesterolemia, hypertensive d/o, migraine, gerd, osteoporosis #hst os s/p laser retinopexy DATE_TIME - good laser barricade. > no new breaks, rd precautions #refractive error / presbyopia ou - current glasses are working well for her #cataract os>od - no significant change > observe #cd asymmetry os> od, likely physiologic - iop good - no family hx - cct 620/615 - hvf DATE_TIME full ou DATE_TIME wnl ou DATE_TIME ou > observe , low risk #dry eye > artificial tears fu DATE_TIME, mrx, bat, dilate",
"gpt4_summary": "71 y.o. patient with history of hypercholesterolemia, hypertension, migraine, GERD, osteoporosis, presbyopia and dry eye. Recent laser retinopexy; no new breaks. Cataracts stable. No family history of glaucoma; low risk.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08592",
"image_path": "slo_fundus_08592.jpg",
"filename": "data_08592.npz",
"report": "The 67-year-old female patient has ocular hypertension and early cataracts, but no glaucoma. Her vision is suboptimal but normal when wearing glasses. She is to be continued treatment and observed.",
"age": 67.55,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "assessment and plan 67 y.o. female 1. ocular hypertension -famhx: father (glc vs oht) -tmax 26/27 -pachy: 551/573 -gonio: open ou -hvf DATE_TIME: nonspecific changes ou -hvf DATE_TIME: normal ou -oct DATE_TIME: normal ou -disc photos DATE_TIME: 0.25 / 0.30 >iop stable >cont txe qam ou 2. early cataracts ou -not vis signif >observe 3. suboptimal vision ou -likely amblyopia; pt states her vision is normal/clear when wearing glasses -stable bcva f/u 6 mos: coe, mrx",
"gpt4_summary": "The 67-year-old female patient has ocular hypertension and early cataracts, but no glaucoma. Her vision is suboptimal but normal when wearing glasses. She is to be continued treatment and observed.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08593",
"image_path": "slo_fundus_08593.jpg",
"filename": "data_08593.npz",
"report": "53 yro male with myopia, mild astigmatism, and presbyopia. Discussed glasses for near reading. Has history of scleral lens wearing; now not interested. Glaucoma suspect due to enlarged c/d ratio.",
"age": 53.87,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "53 yro male PERSON anesthesiologist 1. myopia with mild astigmatism; presbyopia ou - small change in ou - c/o hard for near reading - discusses pal glasses; pt wants to try - new rx=mrx given to pt per request - pt ed adaptation period with pal 2. h/o scls wearing - does not wear cls - not interested in cls exam today 3. glaucoma suspect ou secondary to enlarged c/d ratio - negative f/h glaucoma - iop DATE_TIME: 16/16 - c/d ratio: od: 0.60; os: 0.65; PERSON: 547; osl 544 in DATE_TIME rnfl DATE_TIME: borderline thinning sup and nasal: stable since DATE_TIME; borderline nasally os - oct gcc DATE_TIME: normal ou - hvf in DATE_TIME, DATE_TIME and DATE_TIME: PERSON, monitor DATE_TIME. retinal lattice degeneration ou - no tears/holes, LOCATION precaution reviewed with pt 5. mild mgd/des ou - suggest warm compresses bid - at's prn",
"gpt4_summary": "53 yro male with myopia, mild astigmatism, and presbyopia. Discussed glasses for near reading. Has history of scleral lens wearing; now not interested. Glaucoma suspect due to enlarged c/d ratio.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08595",
"image_path": "slo_fundus_08595.jpg",
"filename": "data_08595.npz",
"report": "Patient has a history of phaco/pciol surgery and shows stable recovery. Also displays stable amblyopia and esotropia, mild and stable ptosis, and itching. Suspect for glaucoma due to increased cup/disc, but pressures are normal, thin corneas and visual field tests are reassuring. OCT shows slight thinning OD.",
"age": 83.06,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "1) s/p phaco/pciol os (DATE_TIME): well-healed, drops stopped 2) s/p phaco/PERSON (DATE_TIME): stable 3) amblyopia/esotropia os: stable 4) ptosis right upper lid: mild, stable - follow 5) itching: mild -zaditor or artificial tears 6) glaucoma suspect (incr cup/disc): pressure are normal, corneas are thin ou, visual field testing is reassuring DATE_TIME. the optical coherence tomography shows slight thinning od but no worsening over DATE_TIME. -no meds for now -return for testing DATE_TIME, but could stop after that if still stable dfe: 10/20 vf: 10/20 DATE_TIME gonio: 10/16 tmax: 19, 20 cct: 512, 529 fhx: unknown 7) refractive: happy without glasses for distance -cont with only otc for near",
"gpt4_summary": "Patient has a history of phaco/pciol surgery and shows stable recovery. Also displays stable amblyopia and esotropia, mild and stable ptosis, and itching. Suspect for glaucoma due to increased cup/disc, but pressures are normal, thin corneas and visual field tests are reassuring. OCT shows slight thinning OD.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08598",
"image_path": "slo_fundus_08598.jpg",
"filename": "data_08598.npz",
"report": "The patient has mixed mechanism glaucoma, possibly related to an ocular vascular event. They have undergone multiple surgeries, including trabeculectomy and phaco-trabectome. There are recurrent choroidal effusions, and the patient uses Valtrex for stable vision. The intraocular pressure is aimed to be kept in low teens. The patient is hesitant about further surgery due to age. Anti-VEGF injections are used for macular edema. Their visual field remains stable.",
"age": 89.6,
"gender": "male",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "# mixed mechanism glaucoma (poag ou / cacg os): cct 450/440 tm unknown to pt; iop goal is low teens. pt with significant LOCATION os esp. relative to level of on change. PERSON: s/p phaco combined with trabectome DATE_TIME od; s/p combined with trabeculectomy os DATE_TIME. s/p trabeculectomy od DATE_TIME - postop course significant for choroidal effusions which spontaneously resolved over DATE_TIME. progression on vf od may be related to brvo, os may be related to iop elevation prior to trab. \u00ff had had recurrent choroidals od after slow taper of durezol and in context of iop in the single digits. resolved od after restarting durezol although has been recurrent PERSON was high in context of hsv keratitis os/dendrite that resolved with PERSON. b scan DATE_TIME: mild choroidal effusion, no vitreitis \u00ff # brvo od , PERSON ; prev vascular event in os with me os - anti vegf per dr miller # corneal ulcer, od noted DATE_TIME DATE_TIME: minimal improvement with q1 hour vigamox. PERSON added DATE_TIME: appears slightly improved based on description after adding PERSON/day and only using vigamox 4-5x/day od. \u00ff\u00ff\u00ff we prev discussed surgery several times but he is hesitant given age plan: od presumed fungal infection -- resolved becoming pthysical remains on valtrex os vision is stable DATE_TIME macular edema , seeing PERSON getting anti vegf injections tarsorrhaphy left eye intraocular pressure DATE_TIME excellent visual field is stable vs DATE_TIME continue cosopt pf tid os alphagan p tid os zioptan qhs os rhopressa DATE_TIME mths intraocular pressure ; dilate , disc photos",
"gpt4_summary": "The patient has mixed mechanism glaucoma, possibly related to an ocular vascular event. They have undergone multiple surgeries, including trabeculectomy and phaco-trabectome. There are recurrent choroidal effusions, and the patient uses Valtrex for stable vision. The intraocular pressure is aimed to be kept in low teens. The patient is hesitant about further surgery due to age. Anti-VEGF injections are used for macular edema. Their visual field remains stable.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08599",
"image_path": "slo_fundus_08599.jpg",
"filename": "data_08599.npz",
"report": "Patient has cupping in both eyes but low intraocular pressure along with normal visual field and OCT. Also has nuclear sclerosis and dry eyes. Presence of pituitary adenoma.",
"age": 62.24,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "imp: cupping ou, but low iop and normal hvf and oct nuclear sclerosis ou mgd/dry ou pituitary adenoma refr error periocular discomfort os--after concussion and iv glutathione injection --unchanged eye exam plan: warm compr/art tears f/u with pcp cos yrly with hvf and oct",
"gpt4_summary": "Patient has cupping in both eyes but low intraocular pressure along with normal visual field and OCT. Also has nuclear sclerosis and dry eyes. Presence of pituitary adenoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08600",
"image_path": "slo_fundus_08600.jpg",
"filename": "data_08600.npz",
"report": "78 y.o. white, non-hispanic female has no diagnosis of glaucoma. Continues latanoprost with lid wipe use. Potential switch of medications.",
"age": 78.32,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "a 78 y.o. white, non-hispanic female with no diagnosis of glaucoma. latanoprost persists with lid wipe use, consider punctal plugs first then switching medications. the information above was documented by PERSON as a scribe for PERSON on DATE_TIME.",
"gpt4_summary": "78 y.o. white, non-hispanic female has no diagnosis of glaucoma. Continues latanoprost with lid wipe use. Potential switch of medications.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08602",
"image_path": "slo_fundus_08602.jpg",
"filename": "data_08602.npz",
"report": "47-year-old male with vitreous syneresis, myopia/presbyopia, dry eyes, and suspected glaucoma. No family history of glaucoma, open ocular angles, inferior arc deficits in left eye, and retinal thinning observed.",
"age": 48.32,
"gender": "male",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "47 y.o. male # vitreous syneresis ou >rd warning signs and symptoms reviewed with patient. # myopia/presbyopia >cont current wear # dry eyes >at qid prn >warm compresses >discussed taking periodic breaks from prolonged reading and computer use. # glaucoma suspect -pachy 554/547 -neg fhx -gonio: open ou -hvf DATE_TIME: od full; os sup and inf arc deficits -oct DATE_TIME: PERSON thinning (worse); os inf thinning (stable to slightly worse) f/u DATE_TIME: hvf, oct nerve",
"gpt4_summary": "47-year-old male with vitreous syneresis, myopia/presbyopia, dry eyes, and suspected glaucoma. No family history of glaucoma, open ocular angles, inferior arc deficits in left eye, and retinal thinning observed.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08603",
"image_path": "slo_fundus_08603.jpg",
"filename": "data_08603.npz",
"report": "Patient has cancer, hypertension, and hyperlipidemia. Oct optic nerve and MRI orbits with contrast recommended. No mention of glaucoma.",
"age": 69.85,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "cancer 7. htn and hyperlipidemia recommendations: 1. oct optic nerve DATE_TIME. follow up in DATE_TIME with repeated vf, before if needed 3. repeat the mri orbits with contrast it is a pleasure to participate in the care of this patient. please do not hesitate to call with questions. sincerely, PERSON, PERSON spent DATE_TIME with this patient, more than 50% of which was face to face with the patient.",
"gpt4_summary": "Patient has cancer, hypertension, and hyperlipidemia. Oct optic nerve and MRI orbits with contrast recommended. No mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08607",
"image_path": "slo_fundus_08607.jpg",
"filename": "data_08607.npz",
"report": "Patient shows signs of possible glaucoma (increased cup/disc), but tests such as pachymetry, optical coherence tomography, and visual fields are normal. No family glaucoma history.",
"age": 81.33,
"gender": "male",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "married or partnered",
"note": "1) refractive: changed -give new rx for glasses 2) s/p phaco od (DATE_TIME): stable 3) glaucoma suspect (increased cup/disc): pressures are ok; pachymetry is fine, optical coherence tomography is within normal limits and the visual fields show only a right upper LOCATION (old stroke), no family history. gonio is open ou. -repeat testing DATE_TIME dfe: 6/18 vf: DATE_TIME: 12/18 gonio: 12/18 tmax: 17, 17 cct: 516, 532 fhx: no 4) dry eyes: mild -artificial tears as needed 5) s/p phaco os (DATE_TIME): stable",
"gpt4_summary": "Patient shows signs of possible glaucoma (increased cup/disc), but tests such as pachymetry, optical coherence tomography, and visual fields are normal. No family glaucoma history.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08608",
"image_path": "slo_fundus_08608.jpg",
"filename": "data_08608.npz",
"report": "58-year-old male patient with glaucoma in both eyes. Currently on latanoprost and timolol, returned to evening dosage due to unreliable morning administration. Also has cataracts and an epiretinal membrane in the left eye, both visually insignificant, and a repaired peripheral retinal tear.",
"age": 58.59,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "58 m for glaucoma f/u. has tried taking timolol in the am but found that he could not do so reliably, so he has returned to taking in the the evening. # glaucoma, both eyes, on latanoprost qhs ou and timolol qhs os [ s/p slt ou (DATE_TIME PERSON at bmc) [ fhx: unknown [ cct: 535,534 [ oct DATE_TIME: sup > PERSON, PERSON > sup thinning os (may be confounded by erm) [ hvf DATE_TIME: full od, generalized depression with inf nasal defect os - iop acceptable at this time and near physiologic minimum in the left eye - continue latanoprost ou qhs and timolol os qhs (could not take reliably in the morning) # cataract, both eyes. not visually significant in both eyes. - continue to monitor. # epiretinal membrane, left eye. not visually significant enough to warrant surgery. - monitor. # peripheral retinal tear, left eye, s/p laser retinopexy (DATE_TIME) # refractive error - f/u with PERSON as needed rtc DATE_TIME, sooner prn",
"gpt4_summary": "58-year-old male patient with glaucoma in both eyes. Currently on latanoprost and timolol, returned to evening dosage due to unreliable morning administration. Also has cataracts and an epiretinal membrane in the left eye, both visually insignificant, and a repaired peripheral retinal tear.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08609",
"image_path": "slo_fundus_08609.jpg",
"filename": "data_08609.npz",
"report": "Patient to undergo baerveldt tube surgery on left eye, handled by PERSON at LOCATION. Diagnosis: severe primary open angle glaucoma. No blood thinners used.",
"age": 65.12,
"gender": "male",
"race": "black",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "single",
"note": "please schedule this patient (PERSON) for surgery: baerveldt tube laterality: left eye surgeon: PERSON, LOCATION level: 2 diagnoses associated with this procedure for booking: primary open angle glaucoma, severe, left eye anesthesia: mac plus topical and sub-tenon's case duration: DATE_TIME operating time blood thinners: this patient is not on blood thinners please send me confirmation message with the date when scheduled. thank you!",
"gpt4_summary": "Patient to undergo baerveldt tube surgery on left eye, handled by PERSON at LOCATION. Diagnosis: severe primary open angle glaucoma. No blood thinners used.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08613",
"image_path": "slo_fundus_08613.jpg",
"filename": "data_08613.npz",
"report": "The patient's right optic nerve head may display shunted venous blood flow. They've had a supraclinoid aneurysm clipped, and a choroidal nevus OD. Glaucoma isn't directly mentioned.",
"age": 51.29,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "the right optic nerve head -?shunting of venous blood flow because of #1 4. s/p clipping of supraclinoid aneurysm 5. choroidal nevus od -suggested follow up with ophthalmology vs retina. recommendations: 1. review mri once uploaded 2. referral to URLeitag 3. return to neuro-ophthalmology in DATE_TIME, before if needed. it is a pleasure to participate in the care of this patient. please do not hesitate to call with questions. ? sincerely, ? PERSON, PERSON spent DATE_TIME with this patient, more than 50% of which was face to face with the patient.",
"gpt4_summary": "The patient's right optic nerve head may display shunted venous blood flow. They've had a supraclinoid aneurysm clipped, and a choroidal nevus OD. Glaucoma isn't directly mentioned.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08617",
"image_path": "slo_fundus_08617.jpg",
"filename": "data_08617.npz",
"report": "The patient, a 58 y.o. male, is a suspect for glaucoma with increased cup-to-disc ratio and borderline high fixation losses. However, intraocular pressure is possibly within normal limits. There are also early signs of cataracts and refractive error. Follow-up recommended in 6-9 months.",
"age": 58.88,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "assessment/plan: 58 y.o. male 1) glaucoma suspect -incr c/d -famhx neg -iop ?within normal limits (low teens) -tmax: unk. -tgoal: low teens -pachy: 559/530 -oct DATE_TIME: borderline signal strength, sup thinning od, wnl os -oct DATE_TIME: superior PERSON, nl os -hvf DATE_TIME shows ? early LOCATION arcuate defect os (though likely rim artifact), PERSON DATE_TIME: od high false negatives - ? early LOCATION defect vs rim, os borderline high fixation losses - cloverleaf-like pattern -gonio open to ss 360 ou >superior rim somewhat thinner od, which correlates with oct but not with hvf. no evidence of progression on oct. hvf findings out of proportion to on appearance and oct. ? 2) incipient cataracts -not visually significant >observe ? 3) refractive error - rx given at last appt plan: observe f/u 6-9 months with disc photos, hvf (try left eye first) sooner prn i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow. i have reviewed the resident/fellow's notes and made any necessary changes.",
"gpt4_summary": "The patient, a 58 y.o. male, is a suspect for glaucoma with increased cup-to-disc ratio and borderline high fixation losses. However, intraocular pressure is possibly within normal limits. There are also early signs of cataracts and refractive error. Follow-up recommended in 6-9 months.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08618",
"image_path": "slo_fundus_08618.jpg",
"filename": "data_08618.npz",
"report": "A 62 y.o female is suspected of having glaucoma due to cup to disc ratio in both eyes. The retinal nerve fiber layer doesn't exhibit thinning. No family history of glaucoma. She will continue to be monitored without treatment.",
"age": 62.19,
"gender": "female",
"race": "black",
"ethnicity": "hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "first seen by dr. PERSON on DATE_TIME glaucoma medication intolerances: none target iop: DATE_TIME, tmax: unknown / unknown central corneal thickness: 510 / 496 gonioscopy: c35b 1+ ou retinal nerve fiber layer, right eye: no thinning, average 91 um retinal nerve fiber layer, left eye: no thinning, average 93 um visual fields, right eye: non-specific defects visual fields, left eye: non-specific defects family history: mother (no history of glaucoma surgeries or blindness) steroids: none trauma: none asthma/copd: none other medical history and problems: osa, htn, hld, depression assessment/plan: 62 y.o. female # glaucoma suspect due to cup to disc ratio, both eyes - iop acceptable ou, exam and oct reassuring, not a great first vf testing quality - continue to monitor without initiating treatment - return in DATE_TIME for iop check, vf, dilate, oct, disc photos # pterygium, right eye - occasionally gets inflamed, can use chilled artificial tears, not interested in excision at this time # cataract, both eyes - mild, not visually significant, monitor PERSON, md",
"gpt4_summary": "A 62 y.o female is suspected of having glaucoma due to cup to disc ratio in both eyes. The retinal nerve fiber layer doesn't exhibit thinning. No family history of glaucoma. She will continue to be monitored without treatment.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08621",
"image_path": "slo_fundus_08621.jpg",
"filename": "data_08621.npz",
"report": "Patient approved for weight lifting. Target intraocular pressure <= 20 mmhg for both eyes. On dated Cosopt BID OS, which they should continue. Advised to follow medication regimen, use artificial tears as needed, and follow up with Dr. for retina and trauma care. May need lower pressure target and Brimonidine addition if OCT worsens.",
"age": 18.28,
"gender": "male",
"race": "white",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "single",
"note": "continue these activities in the future. following a discussion on DATE_TIME, i approved of him returning to weight lifting. attending's plan: -goal intraocular pressure less than or equal to 20 mmhg, right eye. -goal intraocular pressure less than or equal to 20 mmhg, left eye. -iop at goal od and at goal os on DATE_TIME on cosopt bid os. -continue cosopt bid os. -instructions written/typed/printed out for patient (see table/details under patient instructions) previously. -emphasized adherence to medication regimen. -preservative-free artificial tears as needed. -follow-up with dr. PERSON for retina care. -follow-up with dr. PERSON for trauma care. -mrx given to patient at his request on DATE_TIME. -rtc in DATE_TIME with iop check, arx/mrx, and disc photos ou, sooner prn. if oct worsens further, he may need a much lower goal and brimonidine added. the information above was documented by PERSON as a scribe for PERSON on DATE_TIME.",
"gpt4_summary": "Patient approved for weight lifting. Target intraocular pressure <= 20 mmhg for both eyes. On dated Cosopt BID OS, which they should continue. Advised to follow medication regimen, use artificial tears as needed, and follow up with Dr. for retina and trauma care. May need lower pressure target and Brimonidine addition if OCT worsens.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08624",
"image_path": "slo_fundus_08624.jpg",
"filename": "data_08624.npz",
"report": "The patient is doing well, with a history of a corneal ulcer in the left eye, non-visually significant cataract, and retinal issues. Possible presence of glaucoma, though prior test results are needed for confirmation.",
"age": 66.35,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "asymmetry DATE_TIME (levator repair/fat advancement) - per oculoplastics dr. PERSON - doing well at this time - maintains good upper lid height & contour 5. corneal pannus os - longstanding, stable overall - h/o corneal ulcer in the left eye a long time ago per patient (details unclear) - previously evaluated by dr. PERSON who felt this was possibly 2/2 the ulcer - nonvisually significant - observe 6. operculated retinal PERSON flat per dfe DATE_TIME - no new flashes or floaters per patient - monitor DATE_TIME. cataract ou - nonvisually significant - observe plan: order 3rd new rgp od in the envision aspheric design and ship direct to the patient to compare. may continue wearing the 1st spherical eo pair in the interim. will return front surface toric rgp od for warranty exchange. reviewed proper cl hygiene/care. recommend use of artificial tears/rewetting drops as needed for comfort. continue with use of plus readers over the distance contacts as needed for near activities. retinal detachment precautions reviewed in detail. followup DATE_TIME cl progress evaluation. have new rgp od already inserted DATE_TIME prior to the followup. will also need iop check and gonioscopy thereafter. advised patient to bring copies of her prior glaucoma tests at the next visit for review if possible. rtc sooner as needed with any concerns.",
"gpt4_summary": "The patient is doing well, with a history of a corneal ulcer in the left eye, non-visually significant cataract, and retinal issues. Possible presence of glaucoma, though prior test results are needed for confirmation.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08625",
"image_path": "slo_fundus_08625.jpg",
"filename": "data_08625.npz",
"report": "The patient, a diabetic female, has a history including brain tumor, diabetes with retinopathy, and a recent stroke. Her vision is 20/20 and optic nerves are sharp. No glaucoma is present, but due to large c/d with superior thinning of rims, glaucoma testing is planned next visit.",
"age": 71.22,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "PERSON is a DATE_TIME. female presenting for dmtii. PERSON: dmtii, brain tumor saw dr. PERSONME, referred by dr. PERSON for PERSON saw me DATE_TIME \u00ff # dmtii with retinopathy last a1c 7.4 dx ~2015 previously PERSON, os mild-moderate; DATE_TIME no evidence of PERSON/bg control \u00ff # pvd ou stable - continue to monitor \u00ff # pseudophakia ou od: clear centrally s/p yag os: clear centrally - continue to monitor \u00ff # right sphenoid ring meningioma s/p craniotomy DATE_TIME - no apd - colors full DATE_TIME DATE_TIME - optic nerves sharp - vision 20/20 - previously followed with dr. PERSON; now has neurologist because of a new recent stroke - hvf DATE_TIME reliable and scattered defects but overall full note: rnfl oct performed incidentally. does reveal large c/d with superior thinning of rims - will do baseline glaucoma testing at next visit follow up in DATE_TIME; NRP, rnfl oct, cct, disc photos _____________________ PERSON, md, mph comprehensive ophthalmology LOCATION",
"gpt4_summary": "The patient, a diabetic female, has a history including brain tumor, diabetes with retinopathy, and a recent stroke. Her vision is 20/20 and optic nerves are sharp. No glaucoma is present, but due to large c/d with superior thinning of rims, glaucoma testing is planned next visit.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08627",
"image_path": "slo_fundus_08627.jpg",
"filename": "data_08627.npz",
"report": "The patient has end-stage chronic angle closure glaucoma (CACG) in right eye and moderate-severe CACG in left eye. Left eye pressure measured 10.7. He struggles with follow-up and taking drops.",
"age": 79.93,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "od but was not in enough pain to consider this option at the time #pvd ou plan DATE_TIME: iop tonometry tonometry (ora, DATE_TIME) right left pressure 46.4 10.7 could not get accurate reading on PERSON , comfort od, acceptable PERSON has end-stage cacg right eye, mod-severe os but has difficulty maintaining follow up and taking his drops. *he was last seen by dr. LOCATION in DATE_TIME and is here to re-establish care. he is overdue for testing os (oct rnfl, LOCATION, and hvf all os only). *in DATE_TIME, he was considering enucleation od with oculoplastics due to pain od but has not followed up with glaucoma, cornea, or oculoplastics since that time. *there is scattered peripheral anterior synechiae on gonioscopy left eye, which supports the diagnosis of chronic angle closure glaucoma left eye. *though optical coherence tomography is green left eye, closer inspection shows it to be notched to rim left eye superiorly. *humphrey visual field left eye shows stable inferior attitudinal defect when compared to DATE_TIME. *i am changing his diagnosis left eye to mod-severe chronic angle closure glaucoma. - restart latanoprost once a day at bedtime in the left eye only - goal of od is comfort care - monocular precautions last dilated exam: DATE_TIME ou last oct rnfl: DATE_TIME os only last visual field: DATE_TIME os only baseline disc photos: DATE_TIME os only cell: PHONE_NUMBER return to glaucoma clinic DATE_TIME with intraocular pressure check on ltn *he will see optom on DATE_TIME and they will refract him PERSON acting as scribe for dr. PERSON on DATE_TIME at DATE_TIME.",
"gpt4_summary": "The patient has end-stage chronic angle closure glaucoma (CACG) in right eye and moderate-severe CACG in left eye. Left eye pressure measured 10.7. He struggles with follow-up and taking drops.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08628",
"image_path": "slo_fundus_08628.jpg",
"filename": "data_08628.npz",
"report": "Patient has 20/20 vision with normal color vision. Noted to have optic nerve compression in right eye, caused by a sphenoid meningioma. Also shows signs of thyroid eye disease, potentially related to Hashimoto's disease history. Surgery planned. No mention of glaucoma.",
"age": 51.21,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "nerve compression. on my evaluation, the visual acuity is 20/20 in both eyes with normal color vision ou. there is a clear relative afferent pupillary defect on the right. there is a 4mm proptosis of the right eye which induces a temporal scleral show on abduction. however, the extraocular motility is full ou and the alternate cover test does not reveal any ocular misalignment. cranial nerves v1-v2 function is normal. automated visual fields done with good reliability revealed an inferior arcuate defect on the right. dilated fundus exam revealed swelling of the right optic nerve head. i obtained a ganglion cell segmentation of the macula which demonstrated ganglion cell loss superiorly in the right eye. this correlates with the inferior visual field defect noted DATE_TIME. this patient's findings are consistent with a compressive optic neuropathy in the right eye, induced by a sphenoid meningioma invading the right orbital apex. prominence of the extraocular muscle was also noted on imaging DATE_TIME suggesting thyroid eye disease. the patient has a history of hashimoto's disease which can cause thyroid eye disease, although uncommonly. she has a follow up planned with dr.kasper who is planning a surgery likely in collaboration with dr.PERSON. i would like to see her again DATE_TIME before surgery in order to have a baseline visual function evaluation pre-operatively. impression: 1. sphenoid wing meningioma with invasion of the right orbital apex 2. right compressive optic neuropathy secondary to #1 3. right eye proptosis secondary to #1 recommendations: 1. follow up as planned with dr.PERSON 2. follow-up neuro-ophthalmic examination DATE_TIME before surgery PERSON, PERSON neuro-ophthalmology LOCATION PHONE_NUMBER fax PHONE_NUMBER",
"gpt4_summary": "Patient has 20/20 vision with normal color vision. Noted to have optic nerve compression in right eye, caused by a sphenoid meningioma. Also shows signs of thyroid eye disease, potentially related to Hashimoto's disease history. Surgery planned. No mention of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08629",
"image_path": "slo_fundus_08629.jpg",
"filename": "data_08629.npz",
"report": "The patient has blurry vision in both eyes and mild disc edema bilaterally, raising concern for increased intracranial pressure. Yet, no glaucoma is detected. She has migraine headaches and possibly anti-cholinergic side effects of psychiatric meds.",
"age": 26.64,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "formulation: this patient presents for evaluation due to blurry vision in both eyes for DATE_TIME. she has a history of occasional migraine headaches and is currently experiencing one. her examination shows excellent afferent function. automated perimetry DATE_TIME showed a global depression more so nasally in the right eye, and superior arcuate defect left eye. repeat automated perimetry DATE_TIME was unreliable and showed global depression both eyes. however, her visual fields are full to confrontation bilaterally. fundus exam shows mild disc edema bilaterally. mri brain and mrv showed no abnormalities. ultrasound did not show any optic nerve head drusen. bilateral disc edema raises concern for increased intracranial pressure, although she is not having constant or positional headaches or any other symptoms suggestive of increased intracranial pressure. given that she has excellent afferent function, we will monitor her for now and consider an lp if her symptoms worsen. she is also complaining of blurry vision at near, although she read well at distance DATE_TIME. it is unclear why this is the case. she is on many psychiatric medications, so there may be anti-cholinergic effects that can be affecting her accomodation. we will consider a goldmann visual field at the next visit. impression: 1. bilateral disc edema 2. migraine headaches plan: 1. follow up in DATE_TIME this note was prepared with the assistance of PERSON, PERSON, neuro-ophthalmology resident PERSON, PERSON neuro-ophthalmology LOCATION PHONE_NUMBER fax PHONE_NUMBER cc. PERSON",
"gpt4_summary": "The patient has blurry vision in both eyes and mild disc edema bilaterally, raising concern for increased intracranial pressure. Yet, no glaucoma is detected. She has migraine headaches and possibly anti-cholinergic side effects of psychiatric meds.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08630",
"image_path": "slo_fundus_08630.jpg",
"filename": "data_08630.npz",
"report": "Glaucoma is suspected after observing an increased c:d ratio, this could be from narrow angles though they are currently open and underlying issue has been addressed. No glaucoma in family history.",
"age": 64.82,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "1. glaucoma suspect based on inc c:d ratio ou tmax 16,15 cct 645 ou (thick ou). no family history of glaucoma; s/p lpi ou (DATE_TIME PERSON) to address narrow angle component ou. angles are open and lpis patent ou. ghost images have resolved (were present x DATE_TIME) hvf full ou oct wnl ou dp stable iop controlled ou plan: observe 2. mild cataract is present ou that is not visually significant. observation at this time was recommended. 3. refractive error: a prescription for new glasses was given to the patient DATE_TIME. f/u DATE_TIME, mrx, iop, hvf, md to gonio before dilation, oct and dp",
"gpt4_summary": "Glaucoma is suspected after observing an increased c:d ratio, this could be from narrow angles though they are currently open and underlying issue has been addressed. No glaucoma in family history.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08631",
"image_path": "slo_fundus_08631.jpg",
"filename": "data_08631.npz",
"report": "Patient with membranous nephropathy and idiopathic intracranial hypertension doing well on Diamox. New findings include afferent pupillary defect, visual field defect, and a macular lesion. No glaucoma mentioned.",
"age": 37.47,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "formulation: this patient with a history of membranous nephropathy with a recent flare, currently on rituximab infusions, who presented for a follow up for idiopathic intracranial hypertension. in terms of iih, she is doing well on a total dose of 2000 mg od diamox (the dose was recently increased by her nephrologist in order to treat fluid retention from the nephropathy) and her optic discs look unchanged. however, DATE_TIME she was noted to have new afferent pupillary defect os, new inferior arcuate visual field defect and a LOCATION macular lesion os corresponding to the visual field loss. the patient reports intermittently seeing a 'blurry spot' in her left eye for the past DATE_TIME. we obtained a fluorescein angiogram and an oct through the lesion. there is a thickening of the inner retinal layers on oct and no vitritis, thus inflammatory or infectious etiology seems less likely. notably, the fluorescein angiogram did not show vasculitis. the findings were discussed with the retina fellow dr. PERSON and the patient will be scheduled at the retina clinic within DATE_TIME. i will see her again in DATE_TIME or sooner if needed. impression: 1. idiopathic intracranial pressure 2. membranous nephropathy, on rituximab 3. new (fall, DATE_TIME) superior macular lesion of unknown etiology os \u00ff recommendations: 1. continue diamox 1000mg bid 2. follow-up neuro-ophthalmic examination in DATE_TIME",
"gpt4_summary": "Patient with membranous nephropathy and idiopathic intracranial hypertension doing well on Diamox. New findings include afferent pupillary defect, visual field defect, and a macular lesion. No glaucoma mentioned.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08632",
"image_path": "slo_fundus_08632.jpg",
"filename": "data_08632.npz",
"report": "The patient has ocular hypertension in both eyes and has undergone selective laser trabeculoplasty. There's no thinning of the retinal nerve fiber layer and no visual field compromise. Also noted is a past orbital fracture. No signs of glaucoma.",
"age": 72.44,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "first seen by dr. PERSON on DATE_TIME glaucoma medication intolerances: none target iop: DATE_TIME, tmax: 30 / 23 central corneal thickness: 578 / 585 corneal hysteresis: 11.2 / 11.8 gonioscopy: c35f 2+ ou retinal nerve fiber layer, right eye: no thinning retinal nerve fiber layer, left eye: no thinning visual fields, right eye: full visual fields, left eye: full family history: none steroids: none trauma: fall with left orbital fracture DATE_TIME asthma/copd: none other medical history and problems: hld, s/p gastric sleeve assessment/plan: 72 y.o. female working in Institution grant review # ocular hypertension, both eyes - s/p selective laser trabeculoplasty ou (od DATE_TIME, os DATE_TIME) - iop acceptable ou, vf and oct stable - continue to monitor without initiating topical treatment - return in DATE_TIME for iop check # s/p left orbital floor fracture repair (DATE_TIME) - monitor # cataract, both eyes - mild, not visually significant, monitor - she mentioned that she would be interested in advanced technology lens when time comes for surgery, which would be reasonable if iop and nerves remain healthy PERSON scribing for dr. PERSON i attest that i was present while this encounter was recorded and agree that the information entered by my scribe and updated by me is complete and accurate. PERSON, md",
"gpt4_summary": "The patient has ocular hypertension in both eyes and has undergone selective laser trabeculoplasty. There's no thinning of the retinal nerve fiber layer and no visual field compromise. Also noted is a past orbital fracture. No signs of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08633",
"image_path": "slo_fundus_08633.jpg",
"filename": "data_08633.npz",
"report": "The patient has asymptomatic glaucoma, currently managed by a regimen of various medications. However, due to the extensive treatment, tube shunt surgery is recommended.",
"age": 34.98,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "membrane od asymptomatic monitor plan continue current regimen for now as iop at goal- combigan bid od simbrinza bid od rhopressa qhs od lotemax qhs od latanoprost qhs od acetazolamide po 250mg bid discussed situation with patient. would recommend tube shunt surgery, likely PERSON, in near future given extensive treatment burden. printed information sheet on tube shunts provided. patient to think about it. return DATE_TIME, sooner prn",
"gpt4_summary": "The patient has asymptomatic glaucoma, currently managed by a regimen of various medications. However, due to the extensive treatment, tube shunt surgery is recommended.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08634",
"image_path": "slo_fundus_08634.jpg",
"filename": "data_08634.npz",
"report": "Patient with type 2 diabetes, mild retinopathy, macular edema, asthma, chronic sinusitis, nonalcoholic fatty liver disease, overweight, back pain. No mention of glaucoma.",
"age": 56.28,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "type 2 diabetes mellitus with mild nonproliferative retinopathy and macular edema mild persistent asthma without complication chronic sinusitis health care maintenance nafld (nonalcoholic fatty liver disease) overweight low back pain results summary immunizations administered on date of encounter",
"gpt4_summary": "Patient with type 2 diabetes, mild retinopathy, macular edema, asthma, chronic sinusitis, nonalcoholic fatty liver disease, overweight, back pain. No mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08637",
"image_path": "slo_fundus_08637.jpg",
"filename": "data_08637.npz",
"report": "75-year-old male presents with, most notably, pseudoexfoliation glaucoma in the right eye, with worsening ocular hypertension. This is compounded by his existing optic neuropathy. IOP-lowering therapy was recommended for both eyes, due to the condition's progression.",
"age": 75.85,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "75 m hx nmo, htn, LOCATION, hld, cad s/p cabg, carotid stenosis, ckd, ild initially referred by PERSON for evaluation of ocular hypertension \u00ff # likely pseudoexfoliation glaucoma, right eye, with significantly greater ocular hypertension compared with the last visit. superimposed upon optic neuropathy in the right eye related to neuromyelitis optica. [ fhx: no [ cct: 577,565 [ gonio DATE_TIME: open to cbb ou, no pas , mild sampoelesi line od [ hvf DATE_TIME: generalized depression with paracentral nasal sparing od (comparable to DATE_TIME), full os [ oct DATE_TIME: superior and inferior thinning od, full os - given high iop, discussed high risk of progressive glaucomatous optic neuropathy superimposed on his existing optic neuropathy in the right eye. recommended iop-lowering therapy in the right eye. - discussed that iop in the left eye is acceptable but borderline; recommended iop lowering in the left eye as well given monocular status. - also discussed that pxf may accelerate cataract growth and may complicate cataract surgery in the future - start latanoprost qhs ou rtc DATE_TIME for iop check, sooner prn\u00ff previously: # cataract, both eyes, not visually significant. - monitor for now. \u00ff # hx neuromyelitis optica with PERSON antibodies, on ivig therapy # optic neuropathy, right eye, due to prior optic neuritis - f/u with PERSON and PERSON (neurology) as scheduled \u00ff",
"gpt4_summary": "75-year-old male presents with, most notably, pseudoexfoliation glaucoma in the right eye, with worsening ocular hypertension. This is compounded by his existing optic neuropathy. IOP-lowering therapy was recommended for both eyes, due to the condition's progression.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08638",
"image_path": "slo_fundus_08638.jpg",
"filename": "data_08638.npz",
"report": "56 y.o. white, non-hispanic male diagnosed with glaucoma. Patient has been consulted and coordinated for care.",
"age": 56.59,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "a 56 y.o. white, non-hispanic male was evaluated and diagnosed with glaucoma. counseling the patient on the medical condition or coordinating care.",
"gpt4_summary": "56 y.o. white, non-hispanic male diagnosed with glaucoma. Patient has been consulted and coordinated for care.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08646",
"image_path": "slo_fundus_08646.jpg",
"filename": "data_08646.npz",
"report": "78-year-old patient with history of ailments including bronchiectasis and osteoporosis. Notes blurred lines resolved with refraction, likely due to astigmatism. Also has cataracts and had strabismus surgery in the past. Awaiting to start ethambutol again. No signs of optic neuropathy or macular disturbance; no signs of glaucoma observed.",
"age": 78.41,
"gender": "female",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "married or partnered",
"note": "78 yo NRP retired cancer pharmacology researcher with history of hypercholesterolemia, gerd, osteoporosis, PERSON's esophagus, bronchiectasis lee with me DATE_TIME. here for f/u after starting ethambutol notes distance isn't as clear in church, doesn't wear glasses. notes sl blur of vertical lines os at near >> resolved with refraction DATE_TIME. cataracts ou -astigmatism os likely cause of monocular diplopia, glare -given mrx in polycarbonates 2/16, updated DATE_TIME. PERSON/dense refractive amblyopia os -s/p strabismus surgery as a teenager -notes left eye drifts outwards occasionally, but not particularly bothered by this 3. pulmonary mai, started ethambutol 800 mg qd (used in past at 1250 mg x DATE_TIME then 750 qd, no problems) (another course DATE_TIME (800 mg qd)) >> 2/16: plans to start ethambutol again, awaiting sensitivities. no signs of optic neuropathy 2/16, with color vision full, no apd. no macular disturbance >> DATE_TIME: on ethambutol, rifampin, azithromycin since DATE_TIME (planned DATE_TIME per patient) macula DATE_TIME: normal, intact ellipsoid layer ou hvf 24-2 DATE_TIME: pt fatigued during examination (first had 10-2 instead of 24-2 hvf) od fixation losses, enlarged bs. similar to prior os high fixation losses, enlarged bs. >> will follow with hvf in DATE_TIME, with enlarged bs ou in setting of fixation losses. hvf 10-2 DATE_TIME: reliable and full ou DATE_TIME: no dyschromatopsia >> hvf DATE_TIME: od fixation losses, enlarged bs similar to prior, full. os full DATE_TIME: PERSON ou, intact ellipsoid layer macula DATE_TIME: wnl ou, intact is/os junction macula DATE_TIME: wnl ou, intact is/os junction macula DATE_TIME: wnl ou PHONE_NUMBER",
"gpt4_summary": "78-year-old patient with history of ailments including bronchiectasis and osteoporosis. Notes blurred lines resolved with refraction, likely due to astigmatism. Also has cataracts and had strabismus surgery in the past. Awaiting to start ethambutol again. No signs of optic neuropathy or macular disturbance; no signs of glaucoma observed.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08647",
"image_path": "slo_fundus_08647.jpg",
"filename": "data_08647.npz",
"report": "Patient has a history of cva and the goal intraocular pressure is 14 mmhg in both eyes. Pressure was above goal on DATE_TIME. Oct worsened on DATE_TIME. Glaucoma hinted by medication regimen and intraocular pressure details.",
"age": 78.33,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "for >DATE_TIME; she is originally from LOCATION. patient has a h/o cva (~1998) with h/o PERSON (not completely evident on hvf on DATE_TIME). she leaves for LOCATION on DATE_TIME! attending's plan: -goal intraocular pressure less than or equal to 14 mmhg, right eye. -goal intraocular pressure less than or equal to 14 mmhg, left eye. -iop above goal od and above goal os on DATE_TIME on combigan bid ou and rhopressa qhs ou. -continue PERSON bid ou => sample given on DATE_TIME. -continue rhopressa qhs ou => sample given on DATE_TIME. -start zioptan qhs ou. -instructions written/typed/printed out for patient (see table/details under patient instructions). -emphasized adherence to medication regimen. -oct worsened ou on DATE_TIME and od on DATE_TIME. -preservative-free artificial tears as needed. -encouraged tight blood glucose, blood pressure and blood cholesterol control. -retinal detachment precautions were reviewed with the patient. -mrx given at patient request on DATE_TIME and DATE_TIME (re-printed from DATE_TIME). -rtc in DATE_TIME with iop check ou, hvf os, dilation ou, and oct rnfl/gcc ou, sooner prn. if above goal or progression in the future, consider slt versus xen gel stent versus versus vyzulta. if rhopressa becomes bothersome od/ou, consider slt od/ou in future. consider punctal plugs ou if dry eye symptoms persist despite increasing pf at usage. the information above was documented by Person as a scribe for PERSON on DATE_TIME. i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "Patient has a history of cva and the goal intraocular pressure is 14 mmhg in both eyes. Pressure was above goal on DATE_TIME. Oct worsened on DATE_TIME. Glaucoma hinted by medication regimen and intraocular pressure details.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08648",
"image_path": "slo_fundus_08648.jpg",
"filename": "data_08648.npz",
"report": "Patient visited Dr. PERSON, suspected of glaucoma but with low suspicion. Eye tests (corneal hysteresis, optic nerve, visual fields, gonioscopy) were normal. No evidence of Glaucoma found.",
"age": 44.56,
"gender": "female",
"race": "white",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "single",
"note": "first seen by PERSON PERSON on DATE_TIME diagnosis: glaucoma suspect low suspicion target iop: / , tmax: ( ) / ( ) central corneal thickness: 648 / 647 corneal hysteresis: 11.5/10.2 gonioscopy: open to ciliary body band both eyes refractive error: od . . / os . . optic nerve findings on initial visit right eye: normal optic nerve findings on initial visit left eye: normal visual fields on initial visit right eye: normal visual fields on initial visit left eye: normal medication history and intolerances at first visit: glaucoma procedures right eye: glaucoma procedures left eye: other eye procedures right eye: other eye procedures left eye: other eye problems right eye: other eye problems left eye: family history: none steroids: none trauma: none asthma: none other medical history and problems: dm2, ckd, hypothyroid, dvt DATE_TIME on apixaban initial note: no evidence of glaucoma, healthy nerves, normal low intraocular pressure, thick corneas plan: follow up DATE_TIME with optometry for dilated exam PERSON scribing for dr. PERSON (DATE_TIME, DATE_TIME) i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "Patient visited Dr. PERSON, suspected of glaucoma but with low suspicion. Eye tests (corneal hysteresis, optic nerve, visual fields, gonioscopy) were normal. No evidence of Glaucoma found.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08652",
"image_path": "slo_fundus_08652.jpg",
"filename": "data_08652.npz",
"report": "The patient is suspected of having glaucoma. Factors include race and family history. Notable findings include retinal nerve fiber layer thinning and high intraocular pressure. The patient is on Latanoprost treatment.",
"age": 79.88,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "glaucoma suspect refered by PERSON risks include race, PERSON (grandmother and aunt) central corneal thickness 510s optical coherence tomography with retinal nerve fiber layer thinning and some segmentation errors humphrey visual field with generalized depression right eye, left eye with possible inferior deficit but not realiable ons with good rim intraocular pressure 22 on latanoprost qhs both eyes continue latanaprost for now, repeat humphrey visual field next visit pciol ou stable \u00ff old crvo od s/p lucentis x 3 (last DATE_TIME) and s/p PERSON (DATE_TIME) and then switched to eylea x 3 (DATE_TIME) to chronic cme when she was lost to follow up oct shows minimal cme with relatively good vision monitor \u00ff type 2 dm bg/bp control allergies - pt reports itching and watering, bothersome - DATE_TIME bid both eyes as needed 6 ml humphrey visual field and intraocular pressure/gonio",
"gpt4_summary": "The patient is suspected of having glaucoma. Factors include race and family history. Notable findings include retinal nerve fiber layer thinning and high intraocular pressure. The patient is on Latanoprost treatment.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08654",
"image_path": "slo_fundus_08654.jpg",
"filename": "data_08654.npz",
"report": "Patient has severe glaucoma with high intraocular pressure. Recommend trabeculectomy for left eye and possibly repeat cyclophotocoagulation for right. Risks and benefits discussed.",
"age": 64.89,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "eyes - continue acetazolamide 250mg qid severe disease intraocular pressure poorly controlled, too high for health of optic nerve recommend trabeculectomy left eye ; some scarring from prior pars plana vitrectomy increased risk of recurrent retinal detachment discussed may need repeat cyclophotocoagulation right eye i discussed the risks/benefits/alternative of trabeculectomy surgery including but not limited to the following: infection, bleeding, droopy lid, double vision, need for additional/repeat procedure if scarring develops, lack of desired iop lowering, need for additional iop lowering medications, prolonged inflammation, possible retinal detachment and rare loss of vision. after this discussion, the patient elected to proceed. i discussed the risks/benefits/alternative of cyclodestructive surgery including but not limited to the following: vision loss, droopy lid, double vision, need for additional/repeat procedure, lack of desired effect, prolonged inflammation, possible progression of cataracts, hypotony. after this discussion, the patient elected to proceed. \u00ff",
"gpt4_summary": "Patient has severe glaucoma with high intraocular pressure. Recommend trabeculectomy for left eye and possibly repeat cyclophotocoagulation for right. Risks and benefits discussed.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08659",
"image_path": "slo_fundus_08659.jpg",
"filename": "data_08659.npz",
"report": "The patient is a 74-year-old female with primary open angle glaucoma. She displays moderate symptoms in the right eye and mild in the left. Her intraocular pressure (IOP) is stable. She has a cataract in both eyes and will return later on for a check-up.",
"age": 74.24,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "assessment and plan first seen by dr. PERSON on DATE_TIME (previously followed by dr. PERSON) glaucoma medication intolerances: none target iop: DATE_TIME, tmax: unknown / unknown central corneal thickness: 536 / 526 gonioscopy: d40f 1+ ou retinal nerve fiber layer, right eye: superior/inferior thinning retinal nerve fiber layer, left eye: early vertical thinning visual fields, right eye: dense superior arcuate visual fields, left eye: grossly full, watch for inferior arcuate family history: none steroids: none trauma: none asthma/copd: none other medical history and problems: htn, hld, depression, restless leg syndrome, hypothyroidism assessment/plan: 74 y.o. female # primary open angle glaucoma, moderate right eye, mild left eye - iop acceptable ou - continue brimonidine bid od, PERSON - return in DATE_TIME for iop check, dilate, disc photos - will request records from PERSON's office # cataract, both eyes - mild, not visually significant, monitor PERSON scribing for dr. PERSON i attest that i was present while this encounter was recorded and agree that the information entered by my scribe and updated by me is complete and accurate. PERSON, md",
"gpt4_summary": "The patient is a 74-year-old female with primary open angle glaucoma. She displays moderate symptoms in the right eye and mild in the left. Her intraocular pressure (IOP) is stable. She has a cataract in both eyes and will return later on for a check-up.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08660",
"image_path": "slo_fundus_08660.jpg",
"filename": "data_08660.npz",
"report": "75-year-old male with a history of phacoemulsification surgery showing ocular hypertension, a potential glaucoma suspect. He has normal ocular health on most measures, and is responding well to Lumigan.",
"age": 75.94,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "75 y.o. male # s/p phaco/PERSONIME, os DATE_TIME -doing well # glaucoma suspect, ocular hypertension ou -no family hx -tmax 26/27 -pachy: 574/572 -oct rnfl DATE_TIME: normal ou -hvf DATE_TIME: full ou -gonio: open ou -good iop reduction on lumigan >cont lumigan qhs ou # pvd os, PERSON -no retinal detachments/tears >rd warnings signs and symptoms reviewed # blepharitis >warm compresses / lid hygiene bid >omega-3 fatty acids rtc DATE_TIME: coe, hvf, oct nerve",
"gpt4_summary": "75-year-old male with a history of phacoemulsification surgery showing ocular hypertension, a potential glaucoma suspect. He has normal ocular health on most measures, and is responding well to Lumigan.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08663",
"image_path": "slo_fundus_08663.jpg",
"filename": "data_08663.npz",
"report": "The patient is closely monitored off glaucoma medications. They discussed the potential for phaco/ecp surgery due to visually significant cataracts. The patient decided to defer the surgery.",
"age": 79.9,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "close monitoring off glaucoma medications. -retinal detachment precautions were reviewed with the patient. -preservative-free artificial tears as needed. -mrx given upon patient's request on DATE_TIME. -long discussion with patient on DATE_TIME: i think she is a good phaco/ecp candidate od, then os given borderline PERSON and h/o narrow angles. -long discussion with patient on DATE_TIME: given that her cataracts are visually significant od>os, we proceeded with phaco/ecp od on DATE_TIME. we discussed aiming plano od with the potential of monovision with os for near in the future depending on where she ends up od. -rtc in DATE_TIME with iop check ou, arx ou, bat os, optical biometry ou, hvf os, dilation ou, and disc photos ou, sooner prn. patient wishes to defer phaco/ecp for now knowing anisometropia may get in the way of having best vision possible. the information above was documented by PERSON as a scribe for PERSON on DATE_TIME.",
"gpt4_summary": "The patient is closely monitored off glaucoma medications. They discussed the potential for phaco/ecp surgery due to visually significant cataracts. The patient decided to defer the surgery.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08664",
"image_path": "slo_fundus_08664.jpg",
"filename": "data_08664.npz",
"report": "48 y.o. white, non-hispanic male, no glaucoma diagnosis but has cupping, borderline pressures OU. Plan: prescription for glasses.",
"age": 48.49,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "a 48 y.o. white, non-hispanic male with no diagnosis of glaucoma. imp: cupping and borderline pressures ou; testing again unchanged refr error plan: rx=m glasses",
"gpt4_summary": "48 y.o. white, non-hispanic male, no glaucoma diagnosis but has cupping, borderline pressures OU. Plan: prescription for glasses.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08666",
"image_path": "slo_fundus_08666.jpg",
"filename": "data_08666.npz",
"report": "The 62-year-old male patient is a glaucoma suspect due to an increased cup/disc ratio in both eyes, but appears low risk currently. Also has posterior vitreous detachment, cataract (not visually significant), and refractive error.",
"age": 62.43,
"gender": "male",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "62 m hx htn # glaucoma suspect with increased cup/disc ratio, both eyes, with healthy-appearing nerve rims [ fhx: no [ cct: 562,568 [ oct DATE_TIME: PERSON ou [ hvf DATE_TIME: full ou - likely low risk at this time. no intervention required. continue to monitor. # old posterior vitreous detachment, both eyes. no retinal breaks seen. - monitor; return for new symptoms. # cataract, both eyes, not visually significant. - monitor for now. # refractive error (astigmatism and presbyopia), doing well with current over-the-counter glasses. rtc 1 year, sooner prn",
"gpt4_summary": "The 62-year-old male patient is a glaucoma suspect due to an increased cup/disc ratio in both eyes, but appears low risk currently. Also has posterior vitreous detachment, cataract (not visually significant), and refractive error.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08668",
"image_path": "slo_fundus_08668.jpg",
"filename": "data_08668.npz",
"report": "The 45-year-old male patient has a likely diagnosis of glaucoma in both eyes, with progressive nerve fiber layer thinning. An alternate diagnosis could be alcohol optic neuropathy. Patient had a successful selective laser trabeculoplasty in both eyes. He also has dry eye syndrome and a history of a medial canthal cyst in his left eye.",
"age": 45.38,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "45 m hx etoh d/o for f/u of glaucoma # likely glaucoma, both eyes, with progressive nerve fibre layer thinning. ddx is alcohol optic neuropathy though would expect more pallor and less cupping. [ s/p slt 360 deg od DATE_TIME, os DATE_TIME [ fhx: no [ tmax: 33,31 [ cct: 534,523 [ oct DATE_TIME: st and it thinning od, LOCATION > it thinning os [ hvf DATE_TIME: unreliable with central depression od, generalized depression os - discussed importance of etoh cessation. has been doing much better lately. - discussed importance of treatment and f/u for glaucoma; natural history is progressive visual loss and eventual blindness. - doing well s/p selective laser trabeculoplasty in both eyes. no eyedrops needed at this time. \u00ff\u00ff # dry eye syndrome, mild. - artificial tears 1 gtt ou qid prn. - minimize environmental factors (e.g., fans, hair dryers, smoke). \u00ff\u00ff # history of medial canthal cyst, left eye, s/p excision (PERSON) \u00ff\u00ff defers dilation DATE_TIME rtc DATE_TIME with hvf/oct/dilation, sooner prn",
"gpt4_summary": "The 45-year-old male patient has a likely diagnosis of glaucoma in both eyes, with progressive nerve fiber layer thinning. An alternate diagnosis could be alcohol optic neuropathy. Patient had a successful selective laser trabeculoplasty in both eyes. He also has dry eye syndrome and a history of a medial canthal cyst in his left eye.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08669",
"image_path": "slo_fundus_08669.jpg",
"filename": "data_08669.npz",
"report": "The note reports a 77-year-old woman with slightly worsened cataract in her right eye and suspected open-angle glaucoma. Additionally, she has a small area of atrophy in her retina and seasonal allergies.",
"age": 77.87,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "77 yo woman 1) s/p uncomplicated phaco/pciol os DATE_TIME doing well. ? 2) cataract od. slightly worse. pt notices that night driving a bit more challenging. -pt beginning to notice glare. not otherwise bothered. plan: observe ? 3) des - at 4) oag suspect. slight c/d asymmetry (os>od). hvf normal ou DATE_TIME. oct normal. continue to monitor. 5) small area of cr atrophy in nasal midperipheral retina os. unchanged. monitor 6) seasonal allergies - try pataday qd ou. ? return DATE_TIME with iop check and dilated exam.",
"gpt4_summary": "The note reports a 77-year-old woman with slightly worsened cataract in her right eye and suspected open-angle glaucoma. Additionally, she has a small area of atrophy in her retina and seasonal allergies.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08674",
"image_path": "slo_fundus_08674.jpg",
"filename": "data_08674.npz",
"report": "The clinical note doesn't provide specific details about the patient's condition, including the presence or absence of glaucoma.",
"age": 53.83,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "appropriate with the resident/fellow (PERSON, PERSON. i have reviewed the resident/fellow's notes and made any necessary changes. the information above was documented by PERSON as a scribe for PERSON on DATE_TIME.",
"gpt4_summary": "The clinical note doesn't provide specific details about the patient's condition, including the presence or absence of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08675",
"image_path": "slo_fundus_08675.jpg",
"filename": "data_08675.npz",
"report": "The note describes a patient with acute/chronic conditions posing a risk to vision/neurological function. This includes reviewing test results and external documents, test interpretation, and discussions with an unnamed person. The patient has high risk of morbidity. Glaucoma is not mentioned.",
"age": 34.28,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "this case is based upon an assessment of the the patient's acute / chronic problems as detailed under 'diagnoses' above that pose a threat to vision / neurological function or systemic health. my assessment of this case also included review of the following data: 1) results of tests and outside documents (specifically: a review of prior external notes; review of unique test results (including those described under 'ancillary studies' above); ordering unique tests; assessment requiring independent historian); hvf, gcc, gvf 2) independent interpretation of tests performed by PERSON; and 3) discussion or communication or management with PERSON with respect to management, this patient has a - high risk of morbidity related to therapy/elective or major surgery/decision regarding PERSON. - moderate risk of morbidity related to (drug management; minor surgery; treatment limited by social determinants or health). i spent a total of greater than (DATE_TIME preparing for, caring for (face-to-face and non face-to-face), formulating (including review of the presentation with the resident or fellow or of medical tests) and finalizing the visit for this patient.]",
"gpt4_summary": "The note describes a patient with acute/chronic conditions posing a risk to vision/neurological function. This includes reviewing test results and external documents, test interpretation, and discussions with an unnamed person. The patient has high risk of morbidity. Glaucoma is not mentioned.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08682",
"image_path": "slo_fundus_08682.jpg",
"filename": "data_08682.npz",
"report": "The patient is a 72-year-old woman with a history of several conditions including eczema, endometrial cancer, keratoconus, and skin cancer. She is a glaucoma suspect due to a c/d ratio and retinal nerve fiber layer (rnfl) thinning. Other conditions include cataract ou, mgd/blepharitis, choroidal folds od, retinoschisis os and a new lower left lid lesion.",
"age": 72.36,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "72 yo woman with history of eczema, rosacea, s/p endometrial ca surgery DATE_TIME, bcc middle back 1980, melanoma in situ calf ~2005-2010 1. keratoconus -minimal signs (PERSON), subtle fleischer ring od noted DATE_TIME -stopped rgps due to discomfort -saw dr. PERSON in past -saw dr. PERSON DATE_TIME: moderate od and mild os, stable c/w 2013, to f/u prn -declined mrx DATE_TIME and DATE_TIME. mrx DATE_TIME. cataract ou -stable, will follow 3. glaucoma suspect - based on c/d ratio -told of rnfl thinning on exam outside -no family history (limited history) -cct unclear tmax here 17 (usually near 10 ou) gonio open ou hvf DATE_TIME: full ou (od subthreshhold in depression) hvf DATE_TIME: od good reliability, inferior borderline losses, similar to DATE_TIME os good reliability, inferior borderline losses hvf DATE_TIME: od high fixation losses, likely full. os full hvf DATE_TIME (DATE_TIME): reliable ou od: borderline inferonasal depression, PERSON: full, LOCATION oct DATE_TIME: stable ou (shifted peaks ou) oct DATE_TIME: stable ou (shifted peaks ou) oct DATE_TIME: od full. os borderline temporal thinning. stable ou, shifted peaks ou oct DATE_TIME: shifted peak os; full ou >> will follow 4. mgd/blepharitis, mild des -worse with antihistamine use -at prn, wc 5. choroidal folds od - superotemporally with subtle elevation and underlying small choroidal nevus -likely corresponds to area of in depression on hvf 24-2 >> saw dr. aronow DATE_TIME and DATE_TIME, to f/u prn 6. retinoschisis os -inferotemporally, no breaks >> evaluated by dr. PERSON as above, to f/u prn 7. new left lower lid lesion -history of skin cancer - melanoma on back calf, basal cell DATE_TIME -reports DATE_TIME with interval growth, occasional itching, no bleeding, 3.5x3mm with telangiectatic vessels >>referral to oculoplastic",
"gpt4_summary": "The patient is a 72-year-old woman with a history of several conditions including eczema, endometrial cancer, keratoconus, and skin cancer. She is a glaucoma suspect due to a c/d ratio and retinal nerve fiber layer (rnfl) thinning. Other conditions include cataract ou, mgd/blepharitis, choroidal folds od, retinoschisis os and a new lower left lid lesion.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08686",
"image_path": "slo_fundus_08686.jpg",
"filename": "data_08686.npz",
"report": "The patient is a 70-year-old white, non-Hispanic female who displays no signs or diagnosis of glaucoma.",
"age": 70.19,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "a 70 y.o. white, non-hispanic female with no diagnosis of glaucoma. entered by my scribe is complete and accurate.",
"gpt4_summary": "The patient is a 70-year-old white, non-Hispanic female who displays no signs or diagnosis of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08693",
"image_path": "slo_fundus_08693.jpg",
"filename": "data_08693.npz",
"report": "Patient seeking second opinion on new glaucoma diagnosis. Has family history of glaucoma, but showed no signs in the recent examination. Plan is to monitor without therapy.",
"age": 58.07,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "pt here for second opinion on new glc diagnosis pt had dilated exam DATE_TIME by outside PERSON: +family history (mother, brother) cct 563/550 no trauma, no steroid use procedures/meds: none testing: DATE_TIME oct no thinning ou hvf: full normal ou DATE_TIME: iop excellent ou assessment: physiologic cupping without signs of glaucoma plan: monitor off therapy as low risk glc suspect rtc 9-12 months for dfe and repeat oct rnfl ou and repeat hvf ou",
"gpt4_summary": "Patient seeking second opinion on new glaucoma diagnosis. Has family history of glaucoma, but showed no signs in the recent examination. Plan is to monitor without therapy.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08696",
"image_path": "slo_fundus_08696.jpg",
"filename": "data_08696.npz",
"report": "The patient has a cataract and glaucoma (POAG diagnosed by Dr. PERSON). Surgery for cataract deferred for now. Noted possible superior thinning of optic nerve which could lead to irreversible vision loss due to glaucoma. No retinal tears/detachment.",
"age": 89.27,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "married or partnered",
"note": "cataract os - plan sn6-wf 19.5 - in setting of pxf - dilates well, discussed risks with pxf - defer surgery for now - recheck in DATE_TIME # poag - poag diagnosed by dr. PERSON, was on cosopt/latanoprost, PERSON 18/21 - tmax 25/28 in epic by tonopen - cct - 594/589, thick ou - c/d - 0.3. 0.6 - family history - unknown - last hvf performed - DATE_TIME - full ou, central defects os - DATE_TIME - full od, unable to test os - last oct rnfl performed - DATE_TIME- full od, os with possible superior thinning - DATE_TIME - full od, unable to test os - dilated optic nerve exam performed ou DATE_TIME - discussed potential for progressive irreversible vision loss due to glaucomatous optic neuropathy. - repeat testing os after ce/iol os # posterior vitreous detachment ou - extended ophthalmoscopy shows no retinal tears/detachment. - retinal detachment precautions were reviewed with the patient in detail including increase in and/or change in floaters, worsening flashing lights, and curtains or shadows. - rtc urgently for any of the above signs rtc for ce/iol os, to be scheduled - block/distance PERSON, md",
"gpt4_summary": "The patient has a cataract and glaucoma (POAG diagnosed by Dr. PERSON). Surgery for cataract deferred for now. Noted possible superior thinning of optic nerve which could lead to irreversible vision loss due to glaucoma. No retinal tears/detachment.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08700",
"image_path": "slo_fundus_08700.jpg",
"filename": "data_08700.npz",
"report": "Patient had a follow-up eye exam. Key findings include mild nonproliferative diabetic retinopathy in both eyes and post-op cataract surgery in the right eye. Patient is a glaucoma suspect due to cup/disc asymmetry in left > right eye.",
"age": 62.24,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "DATE_TIME PERSON, PERSON parkman st boston ma 02114 patient: PERSON mr number: NUMBER date of birth: DATE_TIME date of visit: DATE_TIME dear dr. PERSON: i saw our mutual patient, PERSON, for a follow-up eye examination. please find below a summary of the examination, assessment, and plan. thank you for allowing me to participate in this patient's care. vision readings for this visit: va distance LOCATION distance cc va near LOCATION near cc iop right 20/40-1 j2 14 left 20/40 j2 14 assessment and plan: 62 m hx htn, dm previously saw PERSON, last visit DATE_TIME. transferring to the stoneham location. # mild nonproliferative diabetic retinopathy, both eyes, without evidence of clinically significant macular edema. - no specific ocular intervention needed at this time. - importance of blood glucose and blood pressure control discussed with patient. - annual dilated eye exams, sooner prn visual changes. # s/p cataract surgery, right eye (DATE_TIME PERSON), doing well # cataract, left eye. not yet visually significant to warrant surgery in the left eye. - continue to monitor. # glaucoma suspect with cup/disc asymmetry, left > right eye [ fhx: no [ cct: 564,551 [ oct DATE_TIME: full ou [ hvf DATE_TIME: generalized depression ou - previously evaluated by PERSON in DATE_TIME for visual field test suspicious for bitemporal defect; mri unremarkable. - no intervention required at this time. continue to monitor. # refractive error, needs glasses. - new rx given to patient. rtc 1 year, sooner prn if you have questions, please do not hesitate to call me. i look forward to following PERSON with you. sincerely, , PERSON no recipients",
"gpt4_summary": "Patient had a follow-up eye exam. Key findings include mild nonproliferative diabetic retinopathy in both eyes and post-op cataract surgery in the right eye. Patient is a glaucoma suspect due to cup/disc asymmetry in left > right eye.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08704",
"image_path": "slo_fundus_08704.jpg",
"filename": "data_08704.npz",
"report": "The clinical note does not provide specific details on the patient's health status or mention the presence of glaucoma. It refers to moderate risk of morbidity related to treatment and management aspects.",
"age": 73.29,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "retina management 2. neuro-ophthalmic follow-up as needed PERSON, PERSON, neuro-ophthalmology service (this note was prepared with the assistance of dr. PERSON, optometry resident) ----- [administrative formulation. my impression of this case is based upon an assessment of the the patient's acute / chronic problems as detailed under 'diagnoses' above that pose a threat to vision / neurological function or systemic health. my assessment of this case also included review of the following data: 1) results of tests and outside documents (specifically: a review of prior external notes; review of unique test results (including those described under 'ancillary studies' above) 2) independent interpretation of tests performed by drs. PERSON with respect to management, this patient has a . - moderate risk of morbidity related to (drug management; minor surgery; treatment limited by social determinants or health). i spent a total of greater than (DATE_TIME preparing and caring for this patient (face-to-face and non face-to-face); formulating (including review of the presentation with the resident or fellow or review of medical tests) and finalizing the note.]",
"gpt4_summary": "The clinical note does not provide specific details on the patient's health status or mention the presence of glaucoma. It refers to moderate risk of morbidity related to treatment and management aspects.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08706",
"image_path": "slo_fundus_08706.jpg",
"filename": "data_08706.npz",
"report": "Patient has a goal intraocular pressure of 17 mmhg in both eyes, currently off glaucoma medications. Preservative-free artificial tears used as needed.",
"age": 64.33,
"gender": "female",
"race": "white",
"ethnicity": "hispanic",
"language": "spanish",
"maritalstatus": "married or partnered",
"note": "plan: -goal intraocular pressure less than or equal to 17 mmhg, right eye. -goal intraocular pressure less than or equal to 17 mmhg, left eye. -iop *** goal od and *** goal os on 02/23/22off glaucoma medications. -preservative-free artificial tears as needed. -monocular precautions discussed: patient should wear polycarbonate glasses at all times to protect seeing eye. -follow-up with dr. PERSON/dr. PERSON for retina care. -rtc in DATE_TIME with iop check, dilation, pachymetry ou, and disc photos ou, sooner prn. i personally spent DATE_TIME preparing for, caring for the patient (face-to-face and non face-to-face), and finalizing the visit for this patient. the information above was documented by Person as a scribe for PERSON on DATE_TIME. i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate. i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow (neal patel, PERSON. i have reviewed the resident/fellow's notes and made any necessary changes.",
"gpt4_summary": "Patient has a goal intraocular pressure of 17 mmhg in both eyes, currently off glaucoma medications. Preservative-free artificial tears used as needed.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08708",
"image_path": "slo_fundus_08708.jpg",
"filename": "data_08708.npz",
"report": "Patient's vision improved to 20/30 from previous hand motion. Automated perimetry shows field loss. Optic nerve head became pale. Patient has recovered from optic neuritis attack. No mention of glaucoma.",
"age": 73.4,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "formulation: this patient reports improved vision od, and my exam showed marked improvement, now with an acuity of 20/30 (vs. hand motion last time). given this improvement, i was able to obtain automated perimetry, which showed field loss mostly inferiorly and somewhat temporally od. the right optic nerve head has become pale, as expected. enlarged optic nerve cups ou are unchanged. this patient has recovered markedly from her attack of optic neuritis, although the recovery did not occur as quickly with the iv corticosteroids as can sometimes be seen. the specific etiology is not know with certainty - demyelination is a primary consideration, although her age at presentation and lack of cerebral lesions is against this diagnosis. however, her daughter does have a history of ms and rheumatoid arthritis; i had queried whether daughter was ever tested for nmo and mog but patient did not want to pursue this information because of her daughter's psychological condition. she is not being followed by a neurologist. i recommended that she do so and she agreed to see her daughter's neurologist at PERSON. impression: 1. atypical right optic neuritis, ? etiology 2. daughter has 'ms' and rheumatoid arthritis plan: 1. return to neuro-op in DATE_TIME. consultation her daughter's neurology at PERSON, PERSON neuro-ophthalmology LOCATION PHONE_NUMBER fax PHONE_NUMBER",
"gpt4_summary": "Patient's vision improved to 20/30 from previous hand motion. Automated perimetry shows field loss. Optic nerve head became pale. Patient has recovered from optic neuritis attack. No mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08715",
"image_path": "slo_fundus_08715.jpg",
"filename": "data_08715.npz",
"report": "The 69-year-old patient, with a history of hypertension and sciatica, returned from a cruise with viral conjunctivitis. Her mother, a former glaucoma patient, passed away in 2013. The patient displays signs of glaucoma, cataract, and dry eyes, but symptoms have improved after using a hairdryer 4x/week.",
"age": 69.99,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "69 yo bank receptionist with history of htn, sciatica DATE_TIME seen in ew DATE_TIME for viral conjunctivitis after returning from cruise \u00ff 1. c/d asymmetry od>os tmax 20/21. cct 596/616 (thick). +mother was a glaucoma patient of dr. PERSON (passed away 11/13) hvf DATE_TIME: full ou, reliable hvf DATE_TIME: od inferior borderline losses, non-specific. os full. hvf DATE_TIME: full ou (tr enlarged bs od). hvf DATE_TIME: full ou oct DATE_TIME: PERSON ou, stable DATE_TIME: PERSON ou, stable DATE_TIME: wnl ou, stable DATE_TIME: PERSON ou oct DATE_TIME: od borderline inferior thinning. PERSON. disc photos 5/12 >> will follow \u00ff 2. guttae ou continues to have intermittent blurry vision in the am, no worsening. since using hairdryer, has noted improvement, able to work on computer with clarity. defers PERSON (dislikes PERSON). still using hairdryer 4x/wk and it's working well -cct DATE_TIME: 574/564 -cct DATE_TIME: 596/616 \u00ff 3. cataract ou - nvs, monitor >> updated mrx DATE_TIME for reading glasses \u00ff 4. dry eye/mgd - having sx of burning/tearing a few times per wk, very mild spk on exam - rec at prn f/u DATE_TIME PERSON i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow. i have reviewed the resident/fellow's notes and made any necessary changes.",
"gpt4_summary": "The 69-year-old patient, with a history of hypertension and sciatica, returned from a cruise with viral conjunctivitis. Her mother, a former glaucoma patient, passed away in 2013. The patient displays signs of glaucoma, cataract, and dry eyes, but symptoms have improved after using a hairdryer 4x/week.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08718",
"image_path": "slo_fundus_08718.jpg",
"filename": "data_08718.npz",
"report": "The patient is a 69-year-old non-Hispanic white female. She does not have a diagnosis of glaucoma.",
"age": 69.32,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "a 69 y.o. white, non-hispanic female with no diagnosis of glaucoma. notes and made any necessary changes.",
"gpt4_summary": "The patient is a 69-year-old non-Hispanic white female. She does not have a diagnosis of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08719",
"image_path": "slo_fundus_08719.jpg",
"filename": "data_08719.npz",
"report": "Patient has limitation in superior visual field OU 3, indicating possible glaucoma. Scheduled for strabismus surgery and pre-op evaluations.",
"age": 70.61,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "limitation in superior visual field ou 3. schedule for strabismus surgery and pre-op evaluations note prepared with assistance from PERSON, neuro-ophthalmology fellow. PERSON, PERSON neuro-ophthalmology LOCATION PHONE_NUMBER fax PHONE_NUMBER",
"gpt4_summary": "Patient has limitation in superior visual field OU 3, indicating possible glaucoma. Scheduled for strabismus surgery and pre-op evaluations.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08720",
"image_path": "slo_fundus_08720.jpg",
"filename": "data_08720.npz",
"report": "The patient has severe primary open angle glaucoma, more advanced in the left eye than right. She wasn't aware how advanced her glaucoma was. Glaucoma surgery is likely. She also has visually significant cataracts.",
"age": 80.78,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "first seen by Person on DATE_TIME. patient referred by dr. PERSON for advanced glaucoma. she was originally schedule for cataract surgery with outside surgeon, but came here for second opinion. she was not aware that her glaucoma was this advanced. diagnosis: primary open angle glaucoma, severe os>od target iop: / , tmax: ( ) / ( ) central corneal thickness: 524 / 526 gonioscopy: ptm/ss od, ss with few pas os refractive error: PERSON . LOCATION . 095 / os +3.50 . DATE_TIME . 140 optic nerve/rnfl findings on baseline visit right eye (DATE_TIME): superior/inferior thinning optic nerve/rnfl findings on baseline visit left eye (DATE_TIME): superior/inferior thinning visual fields on baseline visit right eye (DATE_TIME): deep inferior>superior arcuate visual fields on baseline visit left eye (DATE_TIME): superior altitudinal, deep inferior arcuate medication history at first visit: latanoprost, brimonidine medication intolerances: glaucoma procedures right eye: glaucoma procedures left eye: other eye procedures right eye: other eye procedures left eye: other eye problems right eye: other eye problems left eye: family history: mother, mgm steroids: no trauma: no asthma: no other medical history and problems: assessment: 1. primary open angle glaucoma, severe os>od -discussed likely need for glaucoma surgery -recommend phaco/tube os, consider PERSON vs baerveldt -target iop 12 2. ns cataracts ou -visually significant, glare, difficulty driving -discussed preference for combined phaco/glaucoma surgery plan: -continue latanoprost 1/1, brimonidine 3/3 -start cosopt 2/2 -plan for phaco/tube os, consider PERSON vs baerveldt rtc DATE_TIME for iop check and dilation; okay to schedule phaco/tube os",
"gpt4_summary": "The patient has severe primary open angle glaucoma, more advanced in the left eye than right. She wasn't aware how advanced her glaucoma was. Glaucoma surgery is likely. She also has visually significant cataracts.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08721",
"image_path": "slo_fundus_08721.jpg",
"filename": "data_08721.npz",
"report": "The patient exhibits hyperopia with presbyopia and has a history of narrow angles. However, no glaucoma is present, and normal rnfl & gcl were noted. The patient also has mild ptosis.",
"age": 63.52,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "PERSON: DATE_TIME outside -- pt reports previous clinic is still in the process of faxing notes to Institution dilate pt w/ pe 2.5% hyperopia w/ presbyopia ou pt flies drones optional rx given otc handout given w/ corrections h/o narrow angles ou s/PERSON -- DATE_TIME in LOCATION safe to dilate w/ pe 2.5% risks include: age, c/d asym, increased c/d pt will investigate PERSON oct (DATE_TIME) rnfl and gcl normal ou hvf 24-2 (DATE_TIME) done fhx of amd paternal aunt mild ptosis observe warned interventions may lead to chronic dryness f/u in DATE_TIME for oct, dfe w/ pe 2.5%, ar/refract",
"gpt4_summary": "The patient exhibits hyperopia with presbyopia and has a history of narrow angles. However, no glaucoma is present, and normal rnfl & gcl were noted. The patient also has mild ptosis.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08724",
"image_path": "slo_fundus_08724.jpg",
"filename": "data_08724.npz",
"report": "82yo former construction worker with history of heart disease, atrial fibrillation, severe heart valve regurgitation, cancer, cataract, and partial vision loss. Showed signs of increased c/d ratio, corneal scar. Presence of glaucoma not explicitly mentioned.",
"age": 82.92,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "82 yo former construction worker with history of cad s/p cabg 5/11, atrial fibrillation (s/p pacer DATE_TIME, now on coumadin), severe tr/mr, PERSON and bcc excisions from face, metastatic parotid scc (s/p l total parotidectomy and l neck dissection 3/14), s/p cva DATE_TIME (l carotid occlusion and l crao) 1. cataract od>os >> requested mrx DATE_TIME as backup, given in polycarbonates 2. s/p crao os DATE_TIME - continue monocular precautions 3. rosacea blepharitis ou - has used emn and PERSON in past prn, prefers emn >> refilled DATE_TIME. corneal scar od and mdf os - asymptomatic 5. incr c/d ratio tmax 18 ou. cct 546/528. no fhx. hvf DATE_TIME: od scattered non-specific central depression. os dense depression generalized hvf DATE_TIME: od reliable and full hvf DATE_TIME: od full (50% fixation losses). os unable DATE_TIME: od superior and borderline inferior thinning (similar to DATE_TIME, but sl worse than DATE_TIME) os inferior thinning (inf worse than 1/13, but missing information inferiorly) DATE_TIME: od superior and borderline inferior thinning, sl worse cw 1/13 and 12/11. os superior and inferior thinning, stable oct DATE_TIME: od borderline superior and inferior thinning, stable. os thinning superior and inferiorly, decr signal strength DATE_TIME: od borderline superior and inferior thinning. os thinning - likely real but details of scan likely artifact disc photo DATE_TIME: sloping rim, approx 0.65 od. os 0.8, pallor >> will continue to follow closely in this monocular man. iop great, watch superior PERSON, here for repeat hvf rosacea bleph ou od endothelial/posterior stromal scar superonasal to axis os mdf superiorly LOCATION focally os nc3no2 vitreous os pvd c/d od 0.7 sloping with ppa (difficult to calc rim 2/2 ppa), no disc heme c/d os 0.9 shallow cup, atrophic, pale. ppa os attenuated vessels mild peripheral reticular changes ou os cr scar superotemporally, flat",
"gpt4_summary": "82yo former construction worker with history of heart disease, atrial fibrillation, severe heart valve regurgitation, cancer, cataract, and partial vision loss. Showed signs of increased c/d ratio, corneal scar. Presence of glaucoma not explicitly mentioned.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08730",
"image_path": "slo_fundus_08730.jpg",
"filename": "data_08730.npz",
"report": "The patient has a right eye pressure of 20 and left eye pressure of 21. Their most recent eyeglasses prescription includes a sphere, cylinder, and axis. They are taking lisinopril and metoprolol succinate orally. No mention of glaucoma.",
"age": 70.13,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "married or partnered",
"note": "DATE_TIME's visit (applanation, 9:14 am) right left pressure 20 21 most recent eyeglasses prescription (DATE_TIME) sphere cylinder axis add right +1.00 -1.75 100 +2.50 left +1.25 -1.50 080 +2.50 ???????? ?? ????: DATE_TIME no known allergies medications and orders your current medications lisinopril oral (taking) take by mouth. metoprolol succinate oral (taking) take by mouth. your orders ??????? ??????????? ?? ???? ????? humphrey visual field - ou - both eyes oct, optic nerve - ou - both eyes - cirrus; optic disc; rnfl optic disc photos - ou - both eyes results summary ???????? ??????? ? ???? ??????: DATE_TIME none patient gateway activation information your account is ready to use. activate your account using following steps: 1. visit URL. 2. click 'enroll now' and create your user account.",
"gpt4_summary": "The patient has a right eye pressure of 20 and left eye pressure of 21. Their most recent eyeglasses prescription includes a sphere, cylinder, and axis. They are taking lisinopril and metoprolol succinate orally. No mention of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08731",
"image_path": "slo_fundus_08731.jpg",
"filename": "data_08731.npz",
"report": "72-year-old female has had a stroke, no glaucoma visible but her optic nerve heads look asymmetrical. Other conditions include nuclear sclerosis and refractive error.",
"age": 73.4,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "72f 1. s/p r mca stroke on DATE_TIME (r putamen, r caudate): no vf defect per patient at testing done at mayo clinic - no vf seen DATE_TIME on hvf 2. asymmetric on appearance, c/d od>os, PERSON oct borderline inferior od - hvf full ou 3. nuclear sclerosis ou 4. refractive error ou - new mrx DATE_TIME plan; rx = mrx",
"gpt4_summary": "72-year-old female has had a stroke, no glaucoma visible but her optic nerve heads look asymmetrical. Other conditions include nuclear sclerosis and refractive error.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08733",
"image_path": "slo_fundus_08733.jpg",
"filename": "data_08733.npz",
"report": "21 y.o male with suspected glaucoma due to cup to disc ratio in both eyes. Previously told he had glaucoma in the right eye. Current IOP is acceptable. No treatment needed - will monitor.\n",
"age": 21.7,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "first seen by dr. PERSON on DATE_TIME glaucoma medication intolerances: none target iop: DATE_TIME, tmax: unknown / unknown (never high) central corneal thickness: 513 / 517 corneal hysteresis: 10.3 / 10.1 gonioscopy: d35f 1+ mostly with 3+ inferiorly ou retinal nerve fiber layer, right eye: no thinning retinal nerve fiber layer, left eye: no thinning visual fields, right eye: full visual fields, left eye: full family history: none steroids: none trauma: none asthma/copd: none other medical history and problems: none assessment/plan: 21 y.o. male # glaucoma suspect due to cup to disc ratio, both eyes - reports he was told he had glaucoma in his right eye at PERSON, but more likely physiologic cupping based on nerve exam and testing - iop acceptable ou - continue to monitor without initiating treatment - return in DATE_TIME for iop check, dilate, oct, disc photos PERSON scribing for dr. PERSON i attest that i was present while this encounter was recorded and agree that the information entered by my scribe and updated by me is complete and accurate. PERSON, md",
"gpt4_summary": "21 y.o male with suspected glaucoma due to cup to disc ratio in both eyes. Previously told he had glaucoma in the right eye. Current IOP is acceptable. No treatment needed - will monitor.\n",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08734",
"image_path": "slo_fundus_08734.jpg",
"filename": "data_08734.npz",
"report": "Patient has glaucoma in both eyes due to various mechanisms, with open angle glaucoma worse in left eye. Patient has a history of intolerance to medications and limited visual potential due to glaucoma. Current treatment plan includes timolol and latanoprost.",
"age": 81.73,
"gender": "female",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "single",
"note": "attending assessment and plan - glaucoma of both eyes due to combination of mechanisms, open angle glaucoma ou, os worse than od: cct 550/510 - narrow angles s/p peripheral iridotomies ou, angles still narrow but not occludable on gonio DATE_TIME or DATE_TIME, no post-dilation iop spike od in 7/17 -intolerance to medications: ag - caused irritation. - s/p phaco ecp os DATE_TIME, limited visual potential given glaucoma bcva remains 20/30 with no improvement on pinhole but no evidence of cme on DATE_TIME ecp in the right eye DATE_TIME (0.15 to PERSON) - residual inflammation resolved - goal PERSON 12 ou - iop at goal od but dh in DATE_TIME w iop of 12. plan: - timolol od qam (pt was using bid) and c/w cosopt os bid, change to latanoprost ou qhs - note to PERSON will do hvf od every 6 mo. - rtc 3-4 mo for iop check ou. \u00ff - pciol os (sn60wf, power 22.0 d) s/p ce/iol/ ecp in the right eye DATE_TIME (aim plano, loose zonules) plan: see above. \u00ff\u00ff - other: pt speaks mandarin. pt is away from DATE_TIME. PERSON scribing for dr. PERSON (DATE_TIME, DATE_TIME) i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "Patient has glaucoma in both eyes due to various mechanisms, with open angle glaucoma worse in left eye. Patient has a history of intolerance to medications and limited visual potential due to glaucoma. Current treatment plan includes timolol and latanoprost.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08738",
"image_path": "slo_fundus_08738.jpg",
"filename": "data_08738.npz",
"report": "Patient assessed as a glaucoma suspect. Exam shows abnormal contour on OCT, bilateral cataracts, macular hole repair, and 1-2+ nuclear sclerosis. Glaucoma presence undetermined.",
"age": 69.28,
"gender": "female",
"race": "white",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "divorced",
"note": "assessment glaucoma suspect vf completed cupping od s/p repair of macular hole od abnormal contour on oct biltaeral cataracts main ophthalmology exam external exam right left external normal normal slit lamp exam right left lids/lashes normal normal conjunctiva/sclera sutures normal cornea normal normal anterior chamber normal normal iris normal normal lens 2+ nuclear sclerosis 1+ nuclear sclerosis vitreous s/p ppv fundus exam right left disc normal normal c/d ratio 0.55 0.35 macula flat, macular hole closed , erm removed wnl vessels normal normal periphery normal normal plan dilate DATE_TIME",
"gpt4_summary": "Patient assessed as a glaucoma suspect. Exam shows abnormal contour on OCT, bilateral cataracts, macular hole repair, and 1-2+ nuclear sclerosis. Glaucoma presence undetermined.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08742",
"image_path": "slo_fundus_08742.jpg",
"filename": "data_08742.npz",
"report": "The patient has moderate primary angle closure glaucoma in the right eye and is a suspect for the same in the left eye. OCT-RNFL shows early thinning in the right eye. Latest visits show increased IOP and OCT progression, leading to irritation. Plans include possible surgery for intraocular pressure management.",
"age": 73.57,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "?? # moderate primary angle closure glaucoma od / angle closure suspect os - pachymetry (598/563); tmax 18/16; no fhx of glaucoma - s/PERSON with inferior nasal step od; unremarkable os (unreliable ou) - oct-rnfl (73/84) with early inf thinning od - appears occludable od on gonio - tg <= 14 given higher iop at most recent visits in combination with oct progression ou irritation with ltn -stopped visual field right eye is worse DATE_TIME rnfl oct is worse od superiorly 2020 sup PERSON ; DATE_TIME ?? # PERSON/p phaco/iol os by dr. PERSON (DATE_TIME) via superior scleral tunnel incision - s/p complex phaco/iol od (DATE_TIME) - as above # dm2 - no npdr or csme ou - bp and bs control - follow # s/p blepharoplasty and external levator resection ou (DATE_TIME) - per dr. fay social/systemic: dm; asa; goes to fl (LOCATION) in DATE_TIME; allergic to asa, latex, and sulfur plan: rnfl oct right eye may be worse superiorly vs DATE_TIME, left eye is stable visual field right eye likely worse compared to DATE_TIME, left eye is stable recurrent drance him right eye DATE_TIME needs lower intraocular pressure - continue on dorzolamide right eye and combigan tid both eyes plan for endocyclophotocoagulation + kahook i discussed the risks/benefits/alternative of surgery including but not limited to the following: infection, bleeding, droopy lid, double vision, need for additional/repeat procedure if scarring develops, lack of desired iop lowering, need for additional iop lowering medications, prolonged inflammation, possible retinal detachment and rare loss of vision. after this discussion, the patient elected to proceed.",
"gpt4_summary": "The patient has moderate primary angle closure glaucoma in the right eye and is a suspect for the same in the left eye. OCT-RNFL shows early thinning in the right eye. Latest visits show increased IOP and OCT progression, leading to irritation. Plans include possible surgery for intraocular pressure management.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08745",
"image_path": "slo_fundus_08745.jpg",
"filename": "data_08745.npz",
"report": "The patient is suspected of having glaucoma, with worse visual field in the left eye. Other eye problems include refractive error. Past history includes htn, allergies. The patient has no record of prior glaucoma or eye surgery. Follow up in 4 months planned.",
"age": 48.47,
"gender": "female",
"race": "white",
"ethnicity": "hispanic",
"language": "english",
"maritalstatus": "single",
"note": "# first seen by PERSON on DATE_TIME diagnosis: prior pt of PERSONon; not seen since DATE_TIME glaucoma suspect ttarget: / , tmax: ( ) / ( ) untreated 18 both eyes / prior target 20 per PERSONct: 546, 547, 548 / 528, 529, 530 gonioscopy: refractive error: od . . / os . . optic nerve: rnfl oct: vf: med intolerances: prior glaucoma surgery: -- od / -- os other eye surgery: -- od/ -- os fhx: gm+/ steroids: no/ asthma: mild/ trauma: no # [other eye problems] pmhx: htn, allergies plan: visual field worse left eye (fell asleep) possible green progression on rnfl oct both eyes vs DATE_TIME return to clinic 4 mths for PERSON faster-c visual field both eyes dilate, disc photos likely no need for drops yet diagnosis of glaucoma/glaucoma suspect discussed with patient - review of natural history and management options discussed. importance of lifelong follow up and adherence to treatments discussed in order to lower risk of permanent vision loss/blindness from glaucoma. all questions answered. i personally spent DATE_TIME preparing for, caring for this patient's glaucoma, and finalizing the visit for this patient.",
"gpt4_summary": "The patient is suspected of having glaucoma, with worse visual field in the left eye. Other eye problems include refractive error. Past history includes htn, allergies. The patient has no record of prior glaucoma or eye surgery. Follow up in 4 months planned.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08747",
"image_path": "slo_fundus_08747.jpg",
"filename": "data_08747.npz",
"report": "The note discusses a 71 y.o. white, Unknown female who has been diagnosed with glaucoma. There were no pre-visit symptoms or comorbidities present.",
"age": 71.73,
"gender": "female",
"race": "white",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "single",
"note": "a 71 y.o. white, Unknown female was evaluated and diagnosed with glaucoma. PERSON pre-visit symptom screening date: DATE_TIME symptoms fever: no cough: no mild shortness of breath: no sore throat: no muscle aches: no nasal congestion: no loss of smell/taste: no atypical symptom concerning for PERSON: no concerning symptoms or comorbidities: no additional symptom comments:not answered date of symptom onset: not answered pre-visit screening in DATE_TIME, has the patient had a positive or pending DATE_TIME test outside of Institution? no in DATE_TIME, has the patient spent DATE_TIME within 6 feet of anyone currently infected with DATE_TIME? no",
"gpt4_summary": "The note discusses a 71 y.o. white, Unknown female who has been diagnosed with glaucoma. There were no pre-visit symptoms or comorbidities present.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08750",
"image_path": "slo_fundus_08750.jpg",
"filename": "data_08750.npz",
"report": "The patient has toxoplasmosis but no active inflammation or retinitis, chronic retinal detachment, and is suspected of having glaucoma due to increased c/d ratio (possibly physiologic).",
"age": 44.28,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "single",
"note": "1. toxoplasmosis ou - no active inflammation or retinitis od - return in DATE_TIME; sooner prn any new symptoms 2. chronic retinal detachment os s/p ppv/lensectomy/endolaser/cryo/scleral buckle DATE_TIME os - aphakia os - secondary to uveitis/toxo per record - nlp eye with total rd - no eye pain - observe 3. poag suspect od vs physiologic (monocular patient) due to increased c/d ratio, likely physiologic. - previously seen by PERSON PERSON in DATE_TIME who recommended DATE_TIME monitoring but he has not followed up - iop has been in teens without treatment, gonio open - on 0.8, large cup, but healthy rims, no defect on hvf or rnfl oct previously - dr. PERSON had recommended: hvf od, photos, PERSON, dilate od - the patient did not schedule an appointment with glaucoma - will plug patient back in to glaucoma i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow. i have reviewed the resident/fellow's notes and made any necessary changes. \u00ff",
"gpt4_summary": "The patient has toxoplasmosis but no active inflammation or retinitis, chronic retinal detachment, and is suspected of having glaucoma due to increased c/d ratio (possibly physiologic).",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08753",
"image_path": "slo_fundus_08753.jpg",
"filename": "data_08753.npz",
"report": "Patient has glaucoma & experiencing difficulties. Had uveitis in left eye post-birth, flared after cataract extraction. Also has iritis, dry eyes, and epiretinal membrane.",
"age": 75.05,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "visually significant, will hold off on surgery for now - by boland calculations DATE_TIME. will think it over, but having real difficulties. had uveitis left eye only after giving birth and subsequently flared after cataract extraction could consider solumedrol. # iritis # dry eyes # epiretinal membrane, left eye - followed by PERSON valtrex 1000mg once per day po and prednisolone once per day left eye i, PERSON, am acting as scribe for PERSONmd, PERSON for patient on DATE_TIME.",
"gpt4_summary": "Patient has glaucoma & experiencing difficulties. Had uveitis in left eye post-birth, flared after cataract extraction. Also has iritis, dry eyes, and epiretinal membrane.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08755",
"image_path": "slo_fundus_08755.jpg",
"filename": "data_08755.npz",
"report": "Patient has cataract, early AMD, narrow angles, anterior clinoid meningioma, sphenoid sinus mass; pituitary adenoma but no significant field cuts. No evidence of optic nerve head edema or glaucoma. Good glucose control.",
"age": 68.41,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "single",
"note": "PERSON: s/p ce/iol os DATE_TIME, cataract od, early amd, narrow angles s/p lpi ou, previously followed by dr. PERSON: right anterior clinoid meningioma (incidentally found on mri for paresthesias), sphenoid sinus mass c/w pituitary adenoma by biopsy DATE_TIME, dm on glipizide, htn, hld she notes her neurosurgeon dr. PERSON recommended visits here DATE_TIME for evaluation of visual effects of her meningioma or pituitary adenoma. s/p ce/iol od DATE_TIME s/p ce/iol os DATE_TIME - mild pco +donesis of iol os--beware of yag energy in the future history of right anterior clinoid meningioma new sphenoid sinus mass turned out to be pituitary adenoma, s/p biopsy dr. PERSON did hvf 24-2 DATE_TIME reveals no significant field cuts related to pituitary adenoma or meningioma baseline DATE_TIME reveals no areas of rnfl thinning, increased rnfl thickness present od > os without evidence of clinical optic nerve head edema recommend serial testing DATE_TIME with hvf but will change to 30-2 hvf 30-2 (DATE_TIME): normal ou oct (DATE_TIME): gcl and rnfl both normal ou pt neurologist reports DATE_TIME or DATE_TIME visits hx of dm good hba1c no bdr on prior exam hemoglobin a1c date value ref range status DATE_TIME (h) 4.2 - 5.6 % final comment: hba1c levels 5.7-6.4% represent pre-diabetes, indicating impaired glucose control and an increased risk of developing diabetes. the diagnostic hba1c level for diabetes is 6.5% or greater. hba1c levels <4.2% may indicate a hemoglobinopathy or anemia, and an alternative method is recommended to monitor glucose control. dry amd drusen/rpe changes ou discussed PERSON vitamins, diet modification to include more green leafy vegetables, uv light protection, and not smoking home amsler monitoring f/u in DATE_TIME (hvf, oct) optos no dilation",
"gpt4_summary": "Patient has cataract, early AMD, narrow angles, anterior clinoid meningioma, sphenoid sinus mass; pituitary adenoma but no significant field cuts. No evidence of optic nerve head edema or glaucoma. Good glucose control.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08760",
"image_path": "slo_fundus_08760.jpg",
"filename": "data_08760.npz",
"report": "72 y.o. woman experiencing eye irritation and burning sensation. Increased treatment recommended for ocular surface dryness. Patient with history of 'optic neuritis'; optic nerve atrophy detected. No Glaucoma. Ot",
"age": 72.22,
"gender": "female",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "other",
"maritalstatus": "married or partnered",
"note": "72 y.o. woman presenting for cornea evaluation: referred by dr. PERSON patient's daughter translated NRP for patient at patient request DATE_TIME. des ou/mgd ou -schirmer's DATE_TIME 9 os DATE_TIME patient symptomatic with eye irritation os>od and burning sensation os>od recommend increased treatment for ocular surface dryness plan: placed bll punctal plugs DATE_TIME continue restasis 1 drop two times DATE_TIME both eyes (store drop in refrigerator) start doxycycline 50mg orally DATE_TIME (take pill in DATE_TIME with plenty of water, avoid taking with calcium, discussed risk of photosensitivity) (recommend patient restart pepcid orally DATE_TIME) 2. optic nerve atrophy os -patient reports history of 'optic neuritis' os about 16-17 years ago, treated by dr. PERSON -hvf testing confirms enlarged blind spot os DATE_TIME -likely stable over time, but patient requests follow-up with dr. PERSON now and so patient referred to dr. PERSON DATE_TIME. cataracts ou -likely visually significant but patient does not drive at DATE_TIME and patient not bothered by vision currently -monitor for now, if problems with vision will proceed with cataract surgery 4. dermatochalasis bul -patient denies problems with eyelids, monitor 5. vitreous syneresis ou -rd precautions reviewed 6. refractive error ou -continue with current eyeglasses for now follow-up with me in DATE_TIME with replacement of bll punctal plugs, sooner as needed all patient questions and concerns answered. PERSON, md",
"gpt4_summary": "72 y.o. woman experiencing eye irritation and burning sensation. Increased treatment recommended for ocular surface dryness. Patient with history of 'optic neuritis'; optic nerve atrophy detected. No Glaucoma. Ot",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08761",
"image_path": "slo_fundus_08761.jpg",
"filename": "data_08761.npz",
"report": "Female patient with polycystic ovarian syndrome and neck pain diagnosed with Intracranial hypertension (iih). Noted optic nerve anomalies and previous papilledema. No glaucoma mentioned.",
"age": 36.85,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "ovarian syndrome have a much higher risk of developing iih that females of the same weight and age who do not have PERSON. diagnoses. 1. iih (diagnosed in DATE_TIME) with atypical presentation of optic nerve head appearance 2. PERSON, ou, with fine rpe defects, possibly secondary to earlier papilledema 3. polycystic ovarian syndrome 4. musculoskeletal neck pain recommendations. 1. return in DATE_TIME for repeat evaluation, sooner if headaches significantly worsen or vision changes 1. return in DATE_TIME, or within DATE_TIME of new pregnancy, or immediately if new symptoms arise. continue follow-up with local eye care provide for routine eye care. note prepared with assistance from PERSON, neuro-ophthalmology fellow. PERSON, PERSON, neuro-ophthalmology service i spent a total of DATE_TIME personally preparing and caring for this patient (face-to-face and non face-to-face); formulating (including review of the presentation with the resident or fellow or review of medical tests) and finalizing the note.]",
"gpt4_summary": "Female patient with polycystic ovarian syndrome and neck pain diagnosed with Intracranial hypertension (iih). Noted optic nerve anomalies and previous papilledema. No glaucoma mentioned.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08763",
"image_path": "slo_fundus_08763.jpg",
"filename": "data_08763.npz",
"report": "Patient was seen for acute bilateral angle closure, diagnosed as secondary to topiramate use. UBM confirmed bilateral uveal effusions. Target Tmax was 45/62 and optic nerve findings 0.3 in both eyes. No glaucoma procedures done. Other medical history included corneal edema related to angle closure event. Plan included cessation of topiramate.",
"age": 65.21,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "first seen by dr. PERSON on DATE_TIME referred from the er for acute bilateral angle closure diagnosis:topiramate induced/secondary bilateral angle closure (pt had been on topiramate DATE_TIME prior to angle closure event) ubm confirms bilateral uveal effusions 360 consistent with diagnosis of topiramate induced angle closure target iop: / , tmax: 45 (DATE_TIME ) / 62 (DATE_TIME ) central corneal thickness: / gonioscopy: DATE_TIME: no structures/closed both eyes 6/19: open od / poor view, but unable to view structures os refractive error: od . . / os . . optic nerve findings on initial visit right eye: 0.3 optic nerve findings on initial visit left eye: 0.3 visual fields on initial visit right eye: pending visual fields on initial visit left eye: pending medication history and intolerances at first visit: none glaucoma procedures right eye: none glaucoma procedures left eye: none other eye procedures right eye: none other eye procedures left eye: none other eye problems right eye: none other eye problems left eye: none family history: none steroids: none trauma: none asthma: none other medical history and problems: # corneal edema: - may be due the angle closure event - stopped topical cai - cct 6/19: 775 - started PERSON and ggt DATE_TIME social/medical:? htn on hctz plan: stay off topiramate - continue latanoprost qhs both eyes for now continue to taper prednisolone od, DATE_TIME x DATE_TIME then stop taper pf os - 3/2/1 ok stop PERSON and ointment ok to stop atropine bid both eyes, for DATE_TIME pt wishes to go to stoneham - she can't get into LOCATION easily. iop improving with drops rtc 3 wks soneru iop check and repeat octrnflou as i suspect nerve edema more resolved",
"gpt4_summary": "Patient was seen for acute bilateral angle closure, diagnosed as secondary to topiramate use. UBM confirmed bilateral uveal effusions. Target Tmax was 45/62 and optic nerve findings 0.3 in both eyes. No glaucoma procedures done. Other medical history included corneal edema related to angle closure event. Plan included cessation of topiramate.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08772",
"image_path": "slo_fundus_08772.jpg",
"filename": "data_08772.npz",
"report": "Patient has no history of eye injuries, surgeries, steroid use, or family history of glaucoma but has discontinued Topamax for epilepsy. Diagnosis of glaucoma discussed, potential primary angle closure suspected.",
"age": 48.87,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "pacs , first seen nz DATE_TIME, no meds *discontinued topamax after DATE_TIME of use (discontinued DATE_TIME but took a couple of times DATE_TIME) - for epilepsy emmetrope *no history of eye injuries *no history of eye surgeries *no history of steroid use *no family history of glaucoma ttarget: / , tmax: 16 ou cct: 597, 598, 600 / 623, 625, 628 gonioscopy: rnfl oct nml ou , vf nml ou plan: pacs ou but may be due to topomax use long discussion with patient she is to talk to her neurologist, stop the topomax as appropriate substitution made to her meds, rtc in DATE_TIME for repeat gonio and ubm suspect this is primary angle closure will plan for lpi at that time if still closed and no evidence of choroidal expansion s/s acute angle closure discussed in detail with patient, return precautions discussed no dilation diagnosis of glaucoma/glaucoma suspect discussed with patient - review of natural history and management options discussed. importance of lifelong follow up and adherence to treatments discussed in order to lower risk of permanent vision loss/blindness from glaucoma. all questions answered. i spent DATE_TIME with the patient, more than half of which was spent on counseling and coordination of care for this patient's glaucoma",
"gpt4_summary": "Patient has no history of eye injuries, surgeries, steroid use, or family history of glaucoma but has discontinued Topamax for epilepsy. Diagnosis of glaucoma discussed, potential primary angle closure suspected.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08773",
"image_path": "slo_fundus_08773.jpg",
"filename": "data_08773.npz",
"report": "The patient is being referred to ophthalmology and has undergone Humphrey visual field and optic nerve tests in both eyes. They suffer from a hypertensive disorder, otosclerosis, and hearing loss. No specific mention of glaucoma.",
"age": 69.11,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "DATE_TIME nahyoung PERSON, PERSONtitution oph plastics main campus PHONE_NUMBER orders placed this visit ambulatory referral to Institution ophthalmology ambulatory referral to Institution ophthalmology humphrey visual field - ou - both eyes oct, optic nerve - ou - both eyes - cirrus oct, retina - ou - both eyes - cirrus; retina; macula cube, 5 line raster; 6mm length condition list as of DATE_TIME hypertensive disorder otosclerosis hearing loss results summary immunizations administered on date of encounter - DATE_TIME none patient gateway activation information your account is ready to use. activate your account using following steps:",
"gpt4_summary": "The patient is being referred to ophthalmology and has undergone Humphrey visual field and optic nerve tests in both eyes. They suffer from a hypertensive disorder, otosclerosis, and hearing loss. No specific mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08776",
"image_path": "slo_fundus_08776.jpg",
"filename": "data_08776.npz",
"report": "63 y/o female with stable moderate non proliferative diabetic retinopathy, nasal pterygium, cataracts, refractive error, and corneal verticillata. No glaucoma. Using latanoprost.",
"age": 64.28,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "spanish",
"maritalstatus": "widowed",
"note": "63 y/o female presents for DATE_TIME f/u with PERSON assessment: 1. PERSON stable on latanoprost qhs ou testing stable 2. moderate non proliferative diabetic retinopathy ou - last a1c: 8.4% (DATE_TIME) - without macular edema - maintain tight blood sugar and bp control - monitor 3. nasal pterygium os - does not appear symptomatic 4. cataracts ou - od: 2+ ns, 3+ cortical change - os: 2+ ns, 3+ cortical change, 1+ psc she remains happy with vision monitor. 5. refractive error ou 6. corneal verticillata ou - on amiodarone plan: - continue latanoprost ou qhs. - f/u in DATE_TIME , sooner prn. PERSON scribing for dr. PERSON. i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "63 y/o female with stable moderate non proliferative diabetic retinopathy, nasal pterygium, cataracts, refractive error, and corneal verticillata. No glaucoma. Using latanoprost.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08777",
"image_path": "slo_fundus_08777.jpg",
"filename": "data_08777.npz",
"report": "Patient has neovascular glaucoma in the blind right eye with an intraocular pressure of 50. Also has wet AMD. Some medication intolerance noted. Developing facial rash potentially due to brimonidine. Plan is comfort care.",
"age": 80.02,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "# neovascular glaucoma in blind eye od iop 50 DATE_TIME per pt in LOCATION under care of PERSON for wet amd ou prior surgery: pciol ou med intolerance: ttarget: / , tmax: ( ) / ( ) cct: 601 / 590 gonioscopy: open PERSON oct completely normal os vf central defect os due to amd hx lung cancer plan: arrives on cosopt, aphagan, atropine and PERSON ; goal is comfort only -- comfortable now but developed facial rash on the right side since starting drops may be related to brimonidine -- can stop this and see if it improves cont cosopt, atropine and pf bid os is completely healthy and can be monitored DATE_TIME rtc 4-6 LOCATION, unless develops any pain i do not recommend cpc in this nlp eye as there is a risk of so , though remote if continued pain , should consider LOCATION chlorpromazine or enucleation",
"gpt4_summary": "Patient has neovascular glaucoma in the blind right eye with an intraocular pressure of 50. Also has wet AMD. Some medication intolerance noted. Developing facial rash potentially due to brimonidine. Plan is comfort care.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08778",
"image_path": "slo_fundus_08778.jpg",
"filename": "data_08778.npz",
"report": "The patient has glaucoma with intraocular pressure (IOP) persistently above target, despite being on 4 agents. Both eyes received NRP NRP gel stents to control IOP. Future YAG capsulotomy considered.",
"age": 83.92,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "od. -hold PERSON -hold PERSON. -emphasized adherence to medication regimen. -instructions written/typed/printed out for patient (see table/details under patient instructions). -preservative-free artificial tears as needed. -mrx given at patient's request on DATE_TIME. -follow-up with dr. PERSON for refractive care. -long discussion with patient on DATE_TIME: given iop persistently above goal on 4 agents for iop control os, we proceeded with NRP NRP gel stent os on DATE_TIME. -long discussion with patient on DATE_TIME: given iop above goal on 4 agents for iop control od as well as further worsened hvf od and great result os, we proceeded with NRP NRP gel stent od on DATE_TIME. -rtc in DATE_TIME with iop check ou, hvf os (with coaching), dilation ou, and disc photos ou, sooner prn. consider yag capsulotomy in the future depending on dr. PERSON's assessment. the information above was partially documented by Person as a scribe for PERSON on DATE_TIME. i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "The patient has glaucoma with intraocular pressure (IOP) persistently above target, despite being on 4 agents. Both eyes received NRP NRP gel stents to control IOP. Future YAG capsulotomy considered.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08781",
"image_path": "slo_fundus_08781.jpg",
"filename": "data_08781.npz",
"report": "83-year-old male scheduled for yag capsulotomy due to a posterior capsule opacification on the left. He experiences dry eye symptoms, in addition to increased c/d ratio and a suspected undiagnosed case of glaucoma. His medication includes latanoprost.",
"age": 83.9,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "married or partnered",
"note": "83 y.o.\u00ffmale, NRP speaking, here with his son for follow-up after ce/iol os DATE_TIME, ce/iol od DATE_TIME: latanoprost added in DATE_TIME, here for iop check \u00ff\u00ff 1. pseudophakia os vision a little worse DATE_TIME moderate posterior capsule opacification on left wants to schedule yag capsulotomy \u00ff\u00ff 2. PERSON doing well \u00ff\u00ff 4. dry eye symptoms use artificial tears (preservative -free) as needed for symptoms of dry eye warm compresses, lid hygiene with baby shampoo bid, use at prn for symptoms of dry eye. try gel at bedtime \u00ff\u00ff 5. increased c/d ratio PERSON xe no family hx of glaucoma monitor low suspicion pachy thin (NRP), true iop higher than measured oct rnfl DATE_TIME: od sup thin, borderline temp thin, os: PERSON and temp thinning, borderline sup thinning DATE_TIME: od borderline sup thin, os: borderline inf and temp thinning, stable compared to DATE_TIME oct rnfl DATE_TIME: od: sup thinning, borderline temporal thinning os: PERSON and temporal thinning, borderline sup thinning \u00ff\u00ff hvf DATE_TIME: od sup nasal defect hvf DATE_TIME: od sup and PERSON nasal step, os scattered non-specific defects, sup nasal step and sup paracentral defect (possibly from old occipital infarct), stable compared to DATE_TIME hvf DATE_TIME: od: sup and inferior nasal defects, os superior paracentral rec: - continue timolol xe qam - cont latanoprost qhs \u00ff\u00ff 6. subacute infarct in right occipital lobe (old) follow-up with pcp, now on coumadin for a-fib \u00ff\u00ff 7. recent left 7th n palsy no lagophthalmos DATE_TIME",
"gpt4_summary": "83-year-old male scheduled for yag capsulotomy due to a posterior capsule opacification on the left. He experiences dry eye symptoms, in addition to increased c/d ratio and a suspected undiagnosed case of glaucoma. His medication includes latanoprost.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08783",
"image_path": "slo_fundus_08783.jpg",
"filename": "data_08783.npz",
"report": "Patient on glaucoma medication (dorzolamide and latanoprost), exhibiting signs of disease. Post-op from successful laser treatment. Left eye more worrisome, with refractive error and early signs in right eye.",
"age": 64.83,
"gender": "female",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "teens on drops (dorzolamide twice a day both eyes and latanoprost at bedtime both eyes), post selective laser trabeculoplasty both eyes in DATE_TIME. tmax 18/18. no prior fields available; baseline humphrey visual field here with nasal step left eye and early inferior arcuate right eye. left nerve slightly more suspicious than right eye. refractive error is -11 prior to PERSON and cataract surgery. * no optical coherence tomography's in the future plan: pt currently on: dorzolamide bid ou latanoprost qhs both eyes --watch closely, low threshold to switch to cosopt obtain visual field tests from PERSON's office return to clinic DATE_TIME intraocular pressure check and humphrey visual field both eyes i, PERSON, am acting as scribe for PERSONmd, PERSON for patient in PERSON on DATE_TIME. - david s Person, md, phd i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate. pt declined to participate in gms",
"gpt4_summary": "Patient on glaucoma medication (dorzolamide and latanoprost), exhibiting signs of disease. Post-op from successful laser treatment. Left eye more worrisome, with refractive error and early signs in right eye.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08787",
"image_path": "slo_fundus_08787.jpg",
"filename": "data_08787.npz",
"report": "Patient diagnosed with mild primary open angle glaucoma. Medications include latanoprost, rhopressa. Procedures included selective laser on left eye. Maximum intraocular pressure at 27 mmHg. Family history of glaucoma.",
"age": 71.49,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "first seen by PERSON PERSON on DATE_TIME diagnosis: mild primary open angle glaucoma target iop: DATE_TIME, tmax: ( ) / ( ) max = 27 central corneal thickness: 542 / 547 557/586 corneal hysteresis 9.2/10.1 gonioscopy: refractive error: od +1.50 . -0.75 . 115 / os +1.75 . -0.50 . 103 optic nerve findings on initial visit right eye: normal,small optic nerve findings on initial visit left eye: normal,small visual fields on initial visit right eye: normal visual fields on initial visit left eye: normal medications being used at first visit: tried latanoprost, lumigan and travatan, intraocular pressure in DATE_TIME, taking latanoprost, rhopressa. no response to dorzolamide 557/565 medication intolerances: glaucoma procedures right eye: glaucoma procedures left eye: selective laser DATE_TIME outside, minimal response other eye procedures right eye: other eye procedures left eye: other eye problems right eye: transient vision loss DATE_TIME with carotid ultrasound normal other eye problems left eye: family history: mother, sister, brother steroids: trauma: asthma: other medical history and problems: initial note: glaucoma suspect versus early glaucoma intraocular pressure running mid-20s on latanoprost alone, now lower to 18 with rhopressa. had selective laser trabeculoplasty left eye with minimal response, maximum intraocular pressure 27 mmhg, central corneal thickness 542/547 plan: will set target of 22 given healthy nerve and normal visual field. could have selective laser trabeculoplasty or could stop rhopressa (had intraocular pressure around 22 on latanoprost alone). she will stop rhopressa and follow up with faith discs are small so watch closely.",
"gpt4_summary": "Patient diagnosed with mild primary open angle glaucoma. Medications include latanoprost, rhopressa. Procedures included selective laser on left eye. Maximum intraocular pressure at 27 mmHg. Family history of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08788",
"image_path": "slo_fundus_08788.jpg",
"filename": "data_08788.npz",
"report": "Patient has bilateral posterior chamber intraocular lens (PCIOL), posterior vitreous detachment (PVD), minimal macular changes, and refractive error. Vision corrects to 20/70 and 20/80. Temporal RNFL thinning in left eye greater than right observed, suggesting possible optic neuropathy. No mention of glaucoma.",
"age": 62.12,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "single",
"note": "imp: pciol ou pvd ou minimal macular changes ou refr error ou, but corrects to 20/70 and 20/80 dyschromatopsia ou normal oct of mac ou temporal rnfl thinning by oct os>od (corresponds to disc exam) hvf unrel od but suggests sup altitudinal defect os plan: consult with neuro-oph (presumed optic neuropathy)",
"gpt4_summary": "Patient has bilateral posterior chamber intraocular lens (PCIOL), posterior vitreous detachment (PVD), minimal macular changes, and refractive error. Vision corrects to 20/70 and 20/80. Temporal RNFL thinning in left eye greater than right observed, suggesting possible optic neuropathy. No mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08789",
"image_path": "slo_fundus_08789.jpg",
"filename": "data_08789.npz",
"report": "The patient has severe pigmentary glaucoma, more in the right eye than the left. Despite having medication, issues with drop adherence are reported. Both visual fields & OCT appear worse. Progressive surgical options are discussed.",
"age": 47.76,
"gender": "male",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "first seen by dr. PERSON on DATE_TIME glaucoma medication intolerances: target iop: DATE_TIME, tmax: 30 / 44 central corneal thickness: 442 / 473 corneal hysteresis: 8.7 / 9.6 gonioscopy: d40f 4+ ou retinal nerve fiber layer, right eye: superior/inferior thinning retinal nerve fiber layer, left eye: superior/inferior thinning visual fields, right eye: superior > inferior arcuate visual fields, left eye: inferior > superior arcuate family history: none steroids: none trauma: none asthma/copd: none other medical history and problems: htn assessment/plan: 47 y.o. male PERSON in research # pigmentary glaucoma, severe, right > left eye - presented DATE_TIME to dr. PERSON with advanced disease ou, was recommended to start drops but did not until appointment with glaucoma DATE_TIME, when started on latanoprost qhs ou, dorzolamide/timolol bid ou, brimonidine bid ou - iop acceptable ou, but reports significant drop adherence issues, and vf and oct appear worse ou - discussed importance of drop adherence and techniques for remembering, as well as that surgical options are possible if continued issues - continue latanoprost qhs ou, dorzolamide/timolol bid ou, brimonidine bid ou - return in DATE_TIME for iop check, 10-2 vf # s/p myopic prk, both eyes (DATE_TIME) - thin corneas complicate iop evaluation PERSON, LOCATION mba ____________________ i saw and evaluated this patient and discussed the case as appropriate with the resident. i have reviewed the resident's notes and made any necessary changes. PERSON scribing for dr. PERSON i attest that i was present while this encounter was recorded and agree that the information entered by my scribe and updated by me is complete and accurate. PERSON, md",
"gpt4_summary": "The patient has severe pigmentary glaucoma, more in the right eye than the left. Despite having medication, issues with drop adherence are reported. Both visual fields & OCT appear worse. Progressive surgical options are discussed.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08792",
"image_path": "slo_fundus_08792.jpg",
"filename": "data_08792.npz",
"report": "68 y.o. male has visual field defect, c/d asymmetry, cataracts, myopia/presbyopia, history of hsv keratitis, family history of undefined condition, and mild corneal abrasion. No mention of glaucoma.",
"age": 68.47,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "68 y.o. male last seen by me DATE_TIME; before that by dr. PERSON in sleep medicine, works in data science \u00ff assessment: \u00ff 1. visual field defect os present x DATE_TIME evaluated by neuro PERSON (PERSON) unclear etiology has c/d asymmetry although c/d od>os \u00ff 2. cataracts ou - unable to refract to 20/20 - discussed DATE_TIME gradual worsening vision over DATE_TIME; interfering with night driving, work - mac oct DATE_TIME with normal foveal contour ou - motivated for surgery- refer \u00ff 3. myopia/presbyopia - current mrx with prisms esotropia - has not noted significant change-- no double vision *note prism in lenses ou \u00ff 4. h/o hsv keratitis (unknown which eye) as a child treated at columbia presbytarian no recurrences \u00ff 5. family history of LOCATION notes h/o floaters - stable retina flat on dfe DATE_TIME \u00ff 6. c/d assymetry, noted prior, but not glaucoma workup before - rnfl DATE_TIME: od superior rim thinning, os full rims - hvf DATE_TIME: reliable ou; superior field defect os that is stable from prior; od scattered central defects without pattern 7. mild corneal abrasion at limbus od - no fb under lid (everted) - unknown mechanism - appears to be healing already - will sent vigamox eye drop to use three times DATE_TIME od for DATE_TIME; \u00ff plan: refer for cataract evaluation \u00ff f/u in DATE_TIME with dilation and hvf, rnfl oct, cct, or sooner prn.",
"gpt4_summary": "68 y.o. male has visual field defect, c/d asymmetry, cataracts, myopia/presbyopia, history of hsv keratitis, family history of undefined condition, and mild corneal abrasion. No mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08793",
"image_path": "slo_fundus_08793.jpg",
"filename": "data_08793.npz",
"report": "The patient is on multiple medications including a nasal spray, ibuprofen, ketoconazole shampoo, multivitamins, polyethylene glycol, ranitidine, and saw palmetto. Medical conditions include skin cancer, GERD, atrial fibrillation, allergic rhinitis, prostate condition, depression, fatigue, hernia, hyperlipidemia, back pain, colon polyp, and chronic pansinusitis. No mention of glaucoma.",
"age": 60.93,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "mcg/actuation nasal spray 2 sprays by nasal route DATE_TIME. 2 sprays each nostril. ibuprofen (advil,motrin) 600 mg tablet take 1 tablet by mouth every 8 (DATE_TIME as needed. PERSON DATE_TIME prn varchasv malviya DATE_TIME metal med transfer process ketoconazole (nizoral) 2 % shampoo apply topically DATE_TIME. apply to the center of the face during shower then rinse it off in DATE_TIME. PERSON DATE_TIME >PERSON, PERSON DATE_TIME DATE_TIME prn multivitamins capsule take 1 capsule by mouth DATE_TIME. varchasv malviya DATE_TIME metal med transfer process polyethylene glycol (golytely) PHONE_NUMBER -5.86 gram solution take 4,000 ml by mouth once. reported on DATE_TIME varchasv malviya DATE_TIME metal med transfer process ranitidine (zantac) 150 mg tablet take 1 tablet by mouth 2 (two) times a day. PERSON DATE_TIME prn varchasv malviya DATE_TIME metal med transfer process saw palmetto oral take 160 mg by mouth DATE_TIME. new chapter 5lx brand condition list as of DATE_TIME malignant neoplasm of skin gastroesophageal reflux disease atrial fibrillation allergic rhinitis asymmetric prostate depressive disorder fatigue inguinal hernia mixed hyperlipidemia low back pain colon polyp depression healthcare maintenance chronic pansinusitis results summary immunizations administered on date of encounter - DATE_TIME none",
"gpt4_summary": "The patient is on multiple medications including a nasal spray, ibuprofen, ketoconazole shampoo, multivitamins, polyethylene glycol, ranitidine, and saw palmetto. Medical conditions include skin cancer, GERD, atrial fibrillation, allergic rhinitis, prostate condition, depression, fatigue, hernia, hyperlipidemia, back pain, colon polyp, and chronic pansinusitis. No mention of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08797",
"image_path": "slo_fundus_08797.jpg",
"filename": "data_08797.npz",
"report": "The patient has ocular hypertension in both eyes with IOP 30/32 and asthma/COPD, cataract in both eyes, and diabetes without retinopathy. No glaucoma or medication intolerance noted.",
"age": 72.56,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "legally separated",
"note": "first seen by dr. PERSON on DATE_TIME glaucoma medication intolerances: none target iop: DATE_TIME, tmax: 30 / 32 central corneal thickness: 580 / 590 gonioscopy: d40f 1+ ou retinal nerve fiber layer, right eye: no thinning retinal nerve fiber layer, left eye: no thinning visual fields, right eye: grossly full visual fields, left eye: grossly full family history: brother steroids: none trauma: none asthma/copd: possible asthma other medical history and problems: dm, htn assessment/plan: 72 y.o. female # ocular hypertension, both eyes - iop 30/32 with dr. PERSONME, started on latanoprost qhs ou with good response - difficulty with vf testing reliability/fluctuation - iop acceptable ou, vf and oct stable ou - continue latanoprost qhs ou - return in DATE_TIME for iop check # cataract, both eyes - approaching visual significance - biometry obtained DATE_TIME # dm without retinopathy - blood sugar and blood pressure control, DATE_TIME dilated eye exam (last dfe DATE_TIME) # refractive error - dispensed updated mrx DATE_TIME PERSON, PERSON, PERSON___________________ i saw and evaluated this patient and discussed the case as appropriate with the fellow. i have reviewed the fellow's notes and made any necessary changes. PERSON scribing for dr. PERSON i attest that i was present while this encounter was recorded and agree that the information entered by my scribe and updated by me is complete and accurate. PERSON, md",
"gpt4_summary": "The patient has ocular hypertension in both eyes with IOP 30/32 and asthma/COPD, cataract in both eyes, and diabetes without retinopathy. No glaucoma or medication intolerance noted.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08799",
"image_path": "slo_fundus_08799.jpg",
"filename": "data_08799.npz",
"report": "The patient has moderate primary open angle glaucoma in right eye, mild in left. Currently untreated with intraocular pressure (IOP) at 23/21. Side effects from medication observed, considered resuming Travatan and Timolol. May consider selective laser trabeculoplasty (SLT) soon. Patient previously on Plaquenil therapy, no contraindication to continue. Patient is a nurse.",
"age": 55.75,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "- primary open angle glaucoma moderate od, mild os: untreated iop 23/ 21, cct: thick 617/628 possible follicular rxn from combigan, trav causes redness, +fly hx mother (uses drops) disc photos done in 6/13, hvf DATE_TIME: od: 2/14 fl, dense superior and inferior ns; os: low reliability, normal --nfl DATE_TIME: od: superior and inf thinning, os normal unusual to see on asymmetry without much iop asymmetry. nl color plates in 3/14 lost to f/u from DATE_TIME. pt ran out of drops for DATE_TIME. goal iop mid teens od (adjusting for cct), and around 20 os - elevated ou DATE_TIME. plan: - resume travatan ou qhs, resume timolol od qam. - reinforced compliance. - may need to consider slt od soon. if effective, t/c same for os. can arrange for lw on DATE_TIME. - consider neuro-op eval given on asymmetry, although color plates nl. - rtc in 6 wks for iop, NRP and dp's. ? - pt was on plaquenil therapy in the past: on dose <6.5mg/kg/day; no contraindication to continuing therapy - cataracts nvs plan: pt saw PERSON PERSON. to see optom for mrx. - other: pt is a nurse.",
"gpt4_summary": "The patient has moderate primary open angle glaucoma in right eye, mild in left. Currently untreated with intraocular pressure (IOP) at 23/21. Side effects from medication observed, considered resuming Travatan and Timolol. May consider selective laser trabeculoplasty (SLT) soon. Patient previously on Plaquenil therapy, no contraindication to continue. Patient is a nurse.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08803",
"image_path": "slo_fundus_08803.jpg",
"filename": "data_08803.npz",
"report": "The patient has pseudoexfoliation (pxf) glaucoma in both eyes, previously treated at a different institution. They're using latanoprost eye drops and show signs of glaucoma progression in the right eye. Patient also has cataracts.",
"age": 82.03,
"gender": "male",
"race": "white",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "unknown",
"note": "# pxf glaucoma ou, prev followed by NAME INSTITUTION with glaucoma DATE_TIME, treated with drops no fhx arrives on latanoprost qhs ou DATE_TIME PERSON bid ou DATE_TIME ttarget: / , tmax: 24/26 ; iop on drops low teens ou cct: 539 / 555 gonioscopy: rnfl oct - per records progression od; sup/inf thinning ou vf - per records concern for in vf progression od ; PERSON defect, os rim artifact vs sup arc disc heme DATE_TIME od on eliquis for afib # pp os sn60wf +20.5 plan: referred for consideration of LOCATION vs phaco/migs/combined od given recent progression per notes concern for recent progression od however no prior testing available for review -- recommend we obtain this before proceeding further iop currently excellent, given tmax and cct cont drops for now rtc 3-4 mths repeat vf and dilate ou if planning to undergo ce, would recommend migs (either istent or kdb) i spent DATE_TIME with the patient, more than half of which was spent on counseling and coordination of care for this patient's glaucoma and cataracts diagnosis of glaucoma/glaucoma suspect discussed with patient - review of natural history and management options discussed. importance of lifelong follow up and adherence to treatments discussed in order to lower risk of permanent vision loss/blindness from glaucoma. all questions answered.",
"gpt4_summary": "The patient has pseudoexfoliation (pxf) glaucoma in both eyes, previously treated at a different institution. They're using latanoprost eye drops and show signs of glaucoma progression in the right eye. Patient also has cataracts.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08805",
"image_path": "slo_fundus_08805.jpg",
"filename": "data_08805.npz",
"report": "Patient has primary angle closure, cataract, elevated intraocular pressure that was lowered with medication. No damage from glaucoma, occludable angles, normal visual field, and normal retinal nerve fibre layer. Lens extraction may be an option in future.",
"age": 71.4,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "# primary angle closure ou s/p LPI OU (DATE_TIME) - tmax 50s ou (after dilation); cct (pending); no known fhx glaucoma - iop elevated in the setting of dilation into 50s; lowered with diamox, travatan, Brimonidine, Cosopt (drops x 4 rounds) to 30/28 - occludable angles ou on gonio - hvf full ou - oct-rnfl (95/90) wnl ou - iop elevation to 22 os post dilation despite patent lpi - tg <= 18 ou - cosopt bid ou # cataract ou - not yet visually significant - may benefit from early lens extraction given angle closure (discussed previously with dr. hoguet) - follow for now social/systemic: none plan: iop increasing os no def glaucoma damage phaco may be a good option when becomes symptomatic - continue cosopt bid rtc 6 mths bat, mrx, dilate , iol calcs",
"gpt4_summary": "Patient has primary angle closure, cataract, elevated intraocular pressure that was lowered with medication. No damage from glaucoma, occludable angles, normal visual field, and normal retinal nerve fibre layer. Lens extraction may be an option in future.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08806",
"image_path": "slo_fundus_08806.jpg",
"filename": "data_08806.npz",
"report": "Patient has been reminded about precautions. Recommended preservative-free artificial tears as needed. Next visit scheduled for IOP check, dilation, and OCT RNFL/GCC OU. Glaucoma not mentioned.\n",
"age": 70.81,
"gender": "female",
"race": "white",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "married or partnered",
"note": "precautions were reviewed with the patient. -preservative-free artificial tears as needed. -rtc in DATE_TIME with iop check, dilation, and oct rnfl/gcc ou, sooner prn.",
"gpt4_summary": "Patient has been reminded about precautions. Recommended preservative-free artificial tears as needed. Next visit scheduled for IOP check, dilation, and OCT RNFL/GCC OU. Glaucoma not mentioned.\n",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08808",
"image_path": "slo_fundus_08808.jpg",
"filename": "data_08808.npz",
"report": "62-year-old Cantonese-speaking female suspected of having glaucoma due to increased cup:disc ratio. Other conditions include combined senile cataracts Os>Od, macular retinal pigmentary changes Ou, an epiretinal membrane Od, and bilateral upper lid dermatochalasis.",
"age": 62.17,
"gender": "female",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "married or partnered",
"note": "?62f cantonese-speaking with h/o hypertension, hysterectomy seen previously by dr. PERSON, then went to ocb as insurance did not cover meei, then returned here daughter translated in cantonese; husband and patient speak a little mandarin 1. glaucoma suspected based on increased cup:disc ratio ou -tmax here 16/16; 15/17 at ocb -tcurrent 13/13 -cct thin (~510 ou) -hvf DATE_TIME (1st) with suggestion of sa os, did not clearly correlate with onh appearance DATE_TIME: od borderline reliable (high false positives) with superior defect ?lid artifact; os superior nasal step (less superior arcuate) that doesn't correlate with onh appearance or rnfl oct but does possibly correlate with superior cortical wedge DATE_TIME: ou few nonspecific defects likely full DATE_TIME: ou lids taped; od borderline reliable with possible superior arcuate, os full -oct DATE_TIME (at ocb): normal ou by their report -oct DATE_TIME: ou wnl DATE_TIME: ou wnl DATE_TIME: ou PERSON (but avg nfl slightly lower ou) -disc photos: taken DATE_TIME -last dilated: DATE_TIME >> monitor off eyedrops for now but watch hvf and oct closely. 2. combined senile cataracts os>od becoming visually significant but patient states not bothered much by vision at this time >> risks/benefits of cataract surgery discussed again DATE_TIME. prefers no surgery unless absolutely necessary 3. macular retinal pigmentary changes ou and epiretinal membrane od -? ?noted previously >> monitor 4. bilateral upper lid dermatochalasis (os>od) >> offered oculoplastics referral in past; patient deferred 5. refractive error >> a prescription for new glasses was given to the patient DATE_TIME. f/up DATE_TIME with repeat hvf (tape upper lids), disc photos, gonioscopy, no dilation, sooner prn",
"gpt4_summary": "62-year-old Cantonese-speaking female suspected of having glaucoma due to increased cup:disc ratio. Other conditions include combined senile cataracts Os>Od, macular retinal pigmentary changes Ou, an epiretinal membrane Od, and bilateral upper lid dermatochalasis.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08810",
"image_path": "slo_fundus_08810.jpg",
"filename": "data_08810.npz",
"report": "Patient is using Vyzulta once at night, Dorzolamide/Timolol and Brimonidine thrice a day in both eyes. Indicates treatment for glaucoma.",
"age": 77.51,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "vyzulta (green) 1 time per night, both eyes dorzolamide/timolol (blue) 3 times per day, both eyes brimonidine (purple) 3 times per day, both eyes",
"gpt4_summary": "Patient is using Vyzulta once at night, Dorzolamide/Timolol and Brimonidine thrice a day in both eyes. Indicates treatment for glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08814",
"image_path": "slo_fundus_08814.jpg",
"filename": "data_08814.npz",
"report": "The patient had visual field and optic nerve tests on both eyes. Conditions include type 2 diabetes, depression, hypertension, obesity, and seizures. No presence of glaucoma.",
"age": 52.46,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "your orders normal orders this visit humphrey visual field - ou - both eyes oct, optic nerve - ou - both eyes - cirrus; optic disc; rnfl, onh cube condition list as of DATE_TIME cerebrovascular accident acquired immunodeficiency syndrome depression type 2 diabetes mellitus dysplasia of anus compression fracture of vertebral column eczema elevated cholesterol gastroesophageal reflux disease routine adult health maintenance hematemesis hemiparesis herpes labialis history of dvt (deep vein thrombosis) history of herpes zoster hypertension impaired mobility obesity onychomycosis migraine headache seizure disorder tetralogy of fallot vitamin d deficiency xerosis of skin central sleep apnea foot swelling osteoporosis domestic problems results summary immunizations administered on date of encounter - DATE_TIME none",
"gpt4_summary": "The patient had visual field and optic nerve tests on both eyes. Conditions include type 2 diabetes, depression, hypertension, obesity, and seizures. No presence of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08820",
"image_path": "slo_fundus_08820.jpg",
"filename": "data_08820.npz",
"report": "The note mentions optic neuropathy and diplopia but does not explicitly mention glaucoma. Patient's intraocular pressures are at goal in both eyes on Timolol. Patient also has a history of stroke, follows neuro-ophthalmic and retina cares, and uses artificial tears.",
"age": 78.41,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "diplopia/possible optic neuropathy od. -follow-up with dr. PERSON for ?prisms to help diplopia. 8. social/systemic issues: patient resides with his wife (also a patient in my clinic); patient suffers from LOCATION as of DATE_TIME and is on chronic PERSON prednisone. he has a history of stroke as of DATE_TIME. attending's plan: -goal intraocular pressure less than or equal to 12 mmhg, right eye. -goal intraocular pressure less than or equal to 14 mmhg, left eye. -iop ***at goal od and ***at goal os on DATE_TIME on timolol bid ou. -continue timolol bid ou. -emphasized adherence to medication regimen. -encouraged tight blood glucose, blood pressure and blood cholesterol control. -follow-up with dr. PERSON for retina care. -follow-up with dr. PERSON for neuro-ophthalmic care. -follow-up with dr. PERSON/eyelid care. -follow-up with dr. PERSON for ?prisms to help diplopia. -preservative-free artificial tears as needed. -long discussion with patient on DATE_TIME: i will be referring the patient to dr. PERSON for his binocular vision disorder with diplopia. -rtc in DATE_TIME with iop check ou, hvf 10-2 size iii od, oct rnfl/gcc os, and disc photos ou, sooner prn. the information above was documented by PERSON as a scribe for PERSON on DATE_TIME.",
"gpt4_summary": "The note mentions optic neuropathy and diplopia but does not explicitly mention glaucoma. Patient's intraocular pressures are at goal in both eyes on Timolol. Patient also has a history of stroke, follows neuro-ophthalmic and retina cares, and uses artificial tears.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08821",
"image_path": "slo_fundus_08821.jpg",
"filename": "data_08821.npz",
"report": "Clinical note does not provide specific details about patient's issues but suggests high risk of visual or neurological issues based on diagnoses. Glaucoma not mentioned.",
"age": 59.66,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "formulation. my impression of this case is based upon an assessment of the the patient's problems as detailed under 'diagnoses' (listed above) that pose a threat to vision, neurological function or systemic health. my assessment of this case also included review of the following data: 1) results of tests and outside documents; review of unique test results (including those described under 'ancillary studies' above); ordering unique tests; ); 2) independent interpretation of tests performed by dr. PERSON; and 3) discussion or communication of management with PERSON PERSON. with respect to management, this patient has a potentially high risk of visual or neurological morbidity related to the above diagnoses and considerations of management.]",
"gpt4_summary": "Clinical note does not provide specific details about patient's issues but suggests high risk of visual or neurological issues based on diagnoses. Glaucoma not mentioned.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08824",
"image_path": "slo_fundus_08824.jpg",
"filename": "data_08824.npz",
"report": "Patient likely has low tension glaucoma. Has a history of glaucoma, myopic cupping, possible fluctuating intraocular pressure & thin corneas. Also noted pseudophakia, which is stable. Patient has history of shingles.",
"age": 81.23,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "attending's note: 1. likely low tension glaucoma ou vs myopic cupping, hx of dh od. - t max per records mid teens, DATE_TIME low teens on latanaprost - cct thin 520/530 - gonio: open ou - hvf DATE_TIME changes od consistent with PERSON, os - early bjerrum scotoma with corresponding, PERSON. iop os borderline, likely have iop fluctuation. - h/o + drance heme od, but not clear if due to glaucoma progression (minimal PERSON) or due to cll. st p slt os DATE_TIME, doing well, iop is excellent, will csm. - iop goal low teens ou - at goal DATE_TIME, humphrey visual field os worse DATE_TIME 2/2 ptosis. plan: c/w xal ou qhs. - rtc in DATE_TIME for iop and dp's. 2. pseudophakia ou, stable - per dr. PERSON l side in DATE_TIME, persistent k staining w possible ac reaction (post-dilation) os in DATE_TIME plan: referral to cornea for evaluation. - ptosis PERSON, after shingles plan: monitor for now. - other: pt used to see dr. PERSON. pt is hoh and has cll. pt had shingles of the v1 l side in DATE_TIME sydney lovelace scribing for dr. PERSON (DATE_TIME, DATE_TIME) i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "Patient likely has low tension glaucoma. Has a history of glaucoma, myopic cupping, possible fluctuating intraocular pressure & thin corneas. Also noted pseudophakia, which is stable. Patient has history of shingles.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08828",
"image_path": "slo_fundus_08828.jpg",
"filename": "data_08828.npz",
"report": "The female patient, a cardiologist in biotech, has a history of ocular hypertension and family history of glaucoma. Her eye pressure is well controlled, and shows no signs of glaucoma currently. Recommended follow-up.",
"age": 58.12,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "female (cardiologist now in biotech) 1. h/o ohtn ou dating back DATE_TIME. tmax mid-20s ou (?24). never treated. pt is on systemic bb fhx positive, mother s/PERSON, grandmother had glaucoma as well cct 549,546 (average ou) hvf reliable and full ou oct stable ou dp DATE_TIME iop well controlled ou gonio open ou no pathologic cupping observe 2. papillomatosis of rll, rul, and lll removed by dr. PERSONE doing well with no e/o recurrence 3. mild cataracts present ou that are not visually significant. observation at this time was recommended. DATE_TIME/o trauma od from scuba mask 10/2018 with periorbital bruising, no intraocular heme/inflammation 5. re - cpm with otc readers f/u DATE_TIME, mrx, iop, hvf, LOCATION by md, oct and dp mom needs NRP specialist PERSON but we do not have glau there, only mc,lw or stn",
"gpt4_summary": "The female patient, a cardiologist in biotech, has a history of ocular hypertension and family history of glaucoma. Her eye pressure is well controlled, and shows no signs of glaucoma currently. Recommended follow-up.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08831",
"image_path": "slo_fundus_08831.jpg",
"filename": "data_08831.npz",
"report": "Patient is a glaucoma suspect with an acceptable IOP level and no evidence of glaucoma on visual field exam. To continue monitoring without initiating treatment. Also has cataracts in both eyes, and asteroid hyalosis in left eye.",
"age": 58.09,
"gender": "female",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "first seen by dr. PERSON on DATE_TIME glaucoma medication intolerances: none target iop: 22 / 22, tmax: unknown / unknown (19 / 19 per patient) central corneal thickness: 554 / 566 gonioscopy: c35f 3+ ou retinal nerve fiber layer, right eye: borderline superior thinning retinal nerve fiber layer, left eye: borderline superior thinning visual fields, right eye: no thinning visual fields, left eye: no thinning family history: none steroids: none trauma: none asthma/copd: none other medical history and problems: htn assessment/plan: 58 y.o. female analytical chemist # glaucoma suspect due to cup to disc ratio, both eyes - nerve exam and testing reassuring, no evidence of glaucoma on visual field or optical coherence tomography of optic nerve - iop acceptable ou, vf and oct stable ou - continue to monitor without initiating treatment - return in DATE_TIME for iop check, vf, dilate, oct, disc photos # Asteroid hyalosis, left eye - monitor # cataract, both eyes - mild, not visually significant, monitor PERSON scribing for dr. PERSON i attest that i was present while this encounter was recorded and agree that the information entered by my scribe and updated by me is complete and accurate. PERSON, md",
"gpt4_summary": "Patient is a glaucoma suspect with an acceptable IOP level and no evidence of glaucoma on visual field exam. To continue monitoring without initiating treatment. Also has cataracts in both eyes, and asteroid hyalosis in left eye.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08832",
"image_path": "slo_fundus_08832.jpg",
"filename": "data_08832.npz",
"report": "The 66-year-old female patient has primary open-angle glaucoma of indeterminate stage in the right eye and moderate stage in the left eye. Visual fields have worsened, due to myopic degeneration. She underwent successful trabeculectomy but has mild discomfort.",
"age": 66.7,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "brimonidine (irritation, injection); LOCATION and PERSON (cost) target iop: DATE_TIME, tmax: unknown / 42 on maximum treatment including acetazolamide central corneal thickness: 549 / 547 gonioscopy: c35f 2+ ou retinal nerve fiber layer, right eye: difficult image capture, vertical thinning retinal nerve fiber layer, left eye: inferior > superior thinning visual fields, right eye: dense central/inferior scotoma in setting of myopic degeneration visual fields, left eye: inferior arcuate and superior nasal step family history: mother steroids: inhaled trauma: none asthma/copd: none other medical history and problems: migraine assessment/plan: 66 y.o. female paralegal # primary open angle glaucoma, indeterminate stage right eye, moderate left eye - s/p selective laser trabeculoplasty os (ineffective per patient), trabeculectomy os (DATE_TIME, pulled releasable DATE_TIME, laser suture lysis DATE_TIME) - iop acceptable ou, healed well after trabeculectomy but has mild injection and irritation os, though no signs of blebitis or intraocular inflammation - vf od may be worse but high fixation losses, while vf os stable/improved - oct image capture limited od, roughly stable os though signal loss inferiorly - can try prednisolone qd as needed os, but call immediately if worsening injection, photophobia, vision changes, or other concerns - return in DATE_TIME for iop check # myopic degeneration, right >> left eye - baseline vision od counting fingers centrally but vf shows peripheral preservation - monitor # cataract, both eyes - mild, not visually significant, monitor PERSON scribing for dr. PERSON i attest that i was present while this encounter was recorded and agree that the information entered by my scribe and updated by me is complete and accurate. PERSON, md",
"gpt4_summary": "The 66-year-old female patient has primary open-angle glaucoma of indeterminate stage in the right eye and moderate stage in the left eye. Visual fields have worsened, due to myopic degeneration. She underwent successful trabeculectomy but has mild discomfort.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08835",
"image_path": "slo_fundus_08835.jpg",
"filename": "data_08835.npz",
"report": "The patient is taking cod liver oil, epinephrine (epipen), fluorouracil (efudex) and lisinopril. They also suffer from a range of conditions including hyperlipidemia, gout, and basal cell carcinoma. No mention of glaucoma.",
"age": 58.42,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "cod liver oil oil (taking) take 1 tablet by mouth DATE_TIME. epinephrine (epipen) 0.3 mg/0.3 ml (1:1,000) PERSON (taking) as directed. fluorouracil (efudex) 5 % cream (taking) apply topically 2 (two) times a day. to face for DATE_TIME lisinopril (prinivil,zestril) 5 mg tablet (taking) take 0.5 tablets (2.5 mg total) by mouth DATE_TIME. multivitamin oral (taking) take by mouth. your orders future appointments provider department dept phone DATE_TIME DATE_TIME PERSON, PERSON DATE_TIME 8:10 am PERSON, PERSONtitution comprehensive oph main campus PHONE_NUMBER orders placed this visit humphrey visual field - ou - both eyes oct, optic nerve - ou - both eyes - oct, retina - ou - both eyes - cirrus; retina; macula cube, 5 line raster; 6mm length condition list as of DATE_TIME seasonal allergies hyperlipidemia overweight chondromalacia hypertensive disorder basal cell carcinoma of skin gout actinic keratosis routine adult health maintenance results summary immunizations administered on date of encounter - DATE_TIME none",
"gpt4_summary": "The patient is taking cod liver oil, epinephrine (epipen), fluorouracil (efudex) and lisinopril. They also suffer from a range of conditions including hyperlipidemia, gout, and basal cell carcinoma. No mention of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08840",
"image_path": "slo_fundus_08840.jpg",
"filename": "data_08840.npz",
"report": "The patient is a 66-year-old female with severe primary open glaucoma in both eyes, and has undergone past surgeries. She uses medication including latanoprost, brimonidine, and prednisolone. She shows no glaucoma medication intolerance.",
"age": 66.63,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "first seen by dr. PERSON on DATE_TIME (previously followed by dr. PERSON, moved from LOCATION to live with daughter) glaucoma medication intolerances: none target iop: DATE_TIME, tmax: DATE_TIME central corneal thickness: 461 / 470 gonioscopy: c35f 2+ ou retinal nerve fiber layer, right eye: advanced vertical thinning retinal nerve fiber layer, left eye: advanced vertical thinning visual fields, right eye: generalized depresison visual fields, left eye: dense superior arcuate family history: father steroids: topical trauma: fall with head strike and concussion DATE_TIME asthma/copd: none other medical history and problems: vitiligo, bradycardia assessment/plan: 66 y.o. female # primary open angle glaucoma, severe, both eyes - s/p trabeculectomy ou (od ~2010 and DATE_TIME, os DATE_TIME), phaco/trabeculectomy ou (od DATE_TIME, os DATE_TIME) - arrived chronically on prednisolone qd ou, ok to continue, unclear if previously had uveitic component, but quiet ou now, will consider stopping in future but continue as long as not bothering her and exam/iop stable - iop acceptable ou, oct stable ou, vf os may be worse, and she attributes it to a change she noticed after fall with head strike, could have component of traumatic optic neuropathy - continue latanoprost qhs ou, brimonidine bid ou, prednisolone qd ou DATE_TIME/week - return in DATE_TIME for iop check, vf os # s/p cataract surgery with posterior chamber intraocular lens, both eyes - monitor PERSON, md",
"gpt4_summary": "The patient is a 66-year-old female with severe primary open glaucoma in both eyes, and has undergone past surgeries. She uses medication including latanoprost, brimonidine, and prednisolone. She shows no glaucoma medication intolerance.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08842",
"image_path": "slo_fundus_08842.jpg",
"filename": "data_08842.npz",
"report": "The patient has glaucoma. Prescribed latanoprost, switched from timoptic xe to cosopt, and started on brimonidine. Reviewed retinal detachment precautions. Future consideration for phaco/bgi treatment, but patient would like to wait until completion of lymphoma therapy.\n",
"age": 68.24,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "DATE_TIME on latanoprost qhs ou and timoptic xe qam ou. -continue latanoprost qhs ou. -switch timoptic xe qam ou to cosopt bid ou. -start brimonidine bid os. -instructions written/typed/printed out for patient (see table/details under patient instructions). -emphasized adherence to medication regimen. -preservative-free artificial tears as needed. -retinal detachment precautions were reviewed with the patient. -follow-up with dr. PERSON for general eye care. -rtc in DATE_TIME with iop check ou, arx ou, bat ou, optical biometry ou, dilation ou, oct rnfl/gcc os, and disc photos ou, sooner prn. consider phaco/ecp/kdb os in the future knowing her guttae may cause prolonged corneal edema; we could also consider phaco/bgi os with LOCATION placement -- patient would like to wait until she completes her therapy for mantle cell lymphoma (DATE_TIME). if above goal, consider brimonidine bid ou (from bid os) and rhopressa qhs os. i spent DATE_TIME with the patient, more than half of which was spent on counseling and coordination of care for this patient's glaucoma and cataracts. the information above was documented by PERSON as a scribe for PERSON on DATE_TIME. i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow (PERSON, md). i have reviewed the resident/fellow's notes and made any necessary changes.",
"gpt4_summary": "The patient has glaucoma. Prescribed latanoprost, switched from timoptic xe to cosopt, and started on brimonidine. Reviewed retinal detachment precautions. Future consideration for phaco/bgi treatment, but patient would like to wait until completion of lymphoma therapy.\n",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08845",
"image_path": "slo_fundus_08845.jpg",
"filename": "data_08845.npz",
"report": "The patient is suspected of having open angle glaucoma. Intraocular pressure readings were 17 and 16, with a max of 22/23. The patient also has microscopic colitis and shows a small inferior defect in the right eye.",
"age": 63.84,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "17.1 12.9 tonometry #2 (applanation, DATE_TIME) right left pressure 17 16 tonometry comments unable to get higher ws ou, pt blinking target and PERSON pressure right left target na na max 22 (DATE_TIME) 23 (DATE_TIME) , acceptable od, acceptable os PERSON is an open angle glaucoma suspect PERSON, here for hvf 10-2, oct rnfl, and dfe. here for earlier than planned visit due to intraocular pressure being 22/23 at retina visit in DATE_TIME. *pt was recently diagnosed with microscopic colitis and was prescribed DATE_TIME tapered dose of budesonide (but did not start due to pt wanting to avoid steroids) *oct retinal nerve fiber layer was overall normal both eyes but borderline superiorly right eye stable from DATE_TIME humphrey visual field DATE_TIME with small inferior defect right eye correlation with optical coherence tomography rnfl right eye but seen prev in DATE_TIME monitor for now, follow field if defect confirmed in field, low threshold to intervene continue to monitor off glc drops last dilated exam: DATE_TIME last oct rnfl: DATE_TIME DATE_TIME: DATE_TIME last visual field: DATE_TIME baseline disc photos: DATE_TIME return to glaucoma clinic 4 PERSON visual field 24-2 right eye only",
"gpt4_summary": "The patient is suspected of having open angle glaucoma. Intraocular pressure readings were 17 and 16, with a max of 22/23. The patient also has microscopic colitis and shows a small inferior defect in the right eye.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08846",
"image_path": "slo_fundus_08846.jpg",
"filename": "data_08846.npz",
"report": "The 59-year-old patient suffers from hypertension, hyperlipidemia, and migraines. Glaucoma is suspected but eye pressure is stable. Other issues include mild dry eye and presbyopia.",
"age": 59.97,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "59 y.o. with hypertension, hyperlipidemia, migraine glaucoma suspect ou - iop ok and stable - cct DATE_TIME - hvf DATE_TIME od full os high false positives DATE_TIME od full os nonspecific defects - DATE_TIME ou wnl ou DATE_TIME ou wnl - nerves appear stable DATE_TIME - + family hx > observe, repeat testing DATE_TIME dry eye /meibomian gland dysfunction - mild dryness DATE_TIME ou > warm compresses, lid hygiene, artificial tears > flax seed / fish oil supplementation presbyopia ou - no significant change > given updated rx for backup fu DATE_TIME, mrx, dilate hvf/ oct",
"gpt4_summary": "The 59-year-old patient suffers from hypertension, hyperlipidemia, and migraines. Glaucoma is suspected but eye pressure is stable. Other issues include mild dry eye and presbyopia.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08848",
"image_path": "slo_fundus_08848.jpg",
"filename": "data_08848.npz",
"report": "The patient has chronic posterior vitreous detachment, DM2 without retinopathy, refractive error and drusen, along with pigment changes in the retina. Temporal artery biopsies tested negative for GCA. No signs of glaucoma.",
"age": 86.56,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "25 cct: 513, 513 fhx: no 5) chronic posterior vitreous detachment ou: stable - observe 6) dm2, no medications yet: no retinopathy on exam; a1c was 6.3 - encourage tight glucose/bp control 7) refractive error: changed -give new rx for glasses DATE_TIME 8) pmr: diagnosed in LOCATION started on prednisone - concern was for gca as well. there is no evidence of this on exam DATE_TIME - the best corrected vision is still excellent, the nerves are normal, the color vision is full ou. bilateral temporal artery biopsies negative. esr 5 crp 1.1 DATE_TIME. he is still very concerned that he has gca. i explained to him that the visual changes os are purely refractive and this could be improved with a pair of glasses. he is also being treated for trigeminal neuralgia now. -cont with his low dose prednisone as prescribed 9) drusen and retinal pigment changes ou: chronic wavy lines on amsler grid but now complaining of some recent changes, no fluid seen on exam. could be from posterior capsule opacification? repeat optical coherence tomography of retina showed only drusen. saw PERSON who started him on areds - last seen by her DATE_TIME. -cont with areds/amsler and f/u with PERSON to reschedule 10) blepharitis: mild - artificial tears and warm compresses",
"gpt4_summary": "The patient has chronic posterior vitreous detachment, DM2 without retinopathy, refractive error and drusen, along with pigment changes in the retina. Temporal artery biopsies tested negative for GCA. No signs of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08849",
"image_path": "slo_fundus_08849.jpg",
"filename": "data_08849.npz",
"report": "The clinical note does not provide specific details about the patient's condition, including any information or diagnosis related to glaucoma.",
"age": 33.45,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "hospital neuro-ophthalmology, Institution pt seen & discussed w/ emilie bergeron, md, neuro-ophthalmology fellow. ? i personally spent DATE_TIME preparing for, caring for the patient (face-to-face and non-face-to-face), and finalizing the visit for this patient. this time excludes any listed procedures.",
"gpt4_summary": "The clinical note does not provide specific details about the patient's condition, including any information or diagnosis related to glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08852",
"image_path": "slo_fundus_08852.jpg",
"filename": "data_08852.npz",
"report": "56yo man with l zygoma orif history, type II diabetes, hypertension underwent exam for vision issues. Exam revealed cortical and ns cataract os>od, likely refractive amblyopia od. No glaucoma mentioned.",
"age": 56.3,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "56 yo man with history of l zygoma orif DATE_TIME (fracture by crowbar), dm2, htn presenting for second opinion eye exam. np DATE_TIME: here with his sister ingrid, with whom he lives with (reports low iq, unemployed, lives in other part of her 2-family). she has many concerns about patient's vision, specifically if anything can be done for his right eye, if there is a legal designation for blindness in that eye, if there is the possibility for referral for services given he his tripping and falling at home (vision od isn't good), and what can be done to optimize the vision in the left eye. 1. cortical and ns cataract os>od -mild photophobia, tearing, and blurry vision. to ensure no other cause for decr'd vision os: -macula oct DATE_TIME: od posterior NRP. os wnl -onh oct DATE_TIME: os borderline inferior thinning screening hvf DATE_TIME DATE_TIME: od unable. os full (isolated superior rim loss) 2. likely refractive amblyopia od - patient with long standing history of what sounds like amblyopia od. underwent patching and multiple surgeries. currently hm, which patient states is his baseline. >> vision rehabilitation referral 3. type ii diabetes diagnosed age 30 - a1c unknown, but with variable sugar control per history - no evidence of proliferative disease on exam DATE_TIME - recommend DATE_TIME eye exam and tight bg control",
"gpt4_summary": "56yo man with l zygoma orif history, type II diabetes, hypertension underwent exam for vision issues. Exam revealed cortical and ns cataract os>od, likely refractive amblyopia od. No glaucoma mentioned.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08856",
"image_path": "slo_fundus_08856.jpg",
"filename": "data_08856.npz",
"report": "63-year-old white, non-hispanic male. No diagnosis of glaucoma. Underwent COVID phone screening.",
"age": 63.7,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "a 63 y.o. white, non-hispanic male with no diagnosis of glaucoma. covid phone screening",
"gpt4_summary": "63-year-old white, non-hispanic male. No diagnosis of glaucoma. Underwent COVID phone screening.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08857",
"image_path": "slo_fundus_08857.jpg",
"filename": "data_08857.npz",
"report": "Female patient with primary open angle glaucoma, severe in left eye, moderate in right eye. She requires glaucoma surgery and uses glaucoma drops. Also, a history of autoimmune disease and osteoarthritis.",
"age": 78.27,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "DATE_TIME. female referred by dr. PERSON lives in LOCATION and followed by dr. PERSON at the eye institute for medicine & surgery in rockledge, LOCATION, fax PHONE_NUMBER \u00ff PERSON: primary open angle glaucoma, moderate right eye, severe left eye, worsening vf, s/p slt os (DATE_TIME nasal, DATE_TIME temporal, DATE_TIME nasal) drusen and erm ou\u00ff pseudophakia ou\u00ff s/p pterygium excision, both eyes (DATE_TIME) peripheral corneal thinning ou - patient notes it has been present since DATE_TIME when she was first told of it - equivocal history of autoimmune disease, never had clear diagnosis, workup in DATE_TIME negative, patient has osteoarthritis with prominent hand involvement - no active areas of thinning, appearance not consistent with senile furrow degeneration, no active areas of thinning - observe for now, okay to proceed with glaucoma surgery (tube preferred over trab) corneal stromal opacities os multiple, small etiologies unknown, related to brimonidine allergy? also has significant PERSON follicular rxn and injection plan: glaucoma drops per dr. PERSON. off brimonidine now. defer steroid. see me as needed.",
"gpt4_summary": "Female patient with primary open angle glaucoma, severe in left eye, moderate in right eye. She requires glaucoma surgery and uses glaucoma drops. Also, a history of autoimmune disease and osteoarthritis.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08858",
"image_path": "slo_fundus_08858.jpg",
"filename": "data_08858.npz",
"report": "Patient first seen by a specialist for suspected glaucoma. Indications suggest probable primary open angle glaucoma in right eye based on OCT and early visual field changes.",
"age": 68.13,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "first seen by PERSON PERSON on DATE_TIME, sg diagnosis: glaucoma suspect target iop: / , tmax: ( ) / ( ) central corneal thickness: / 531/514 gonioscopy: refractive error: od . . / os . . optic nerve findings on initial visit right eye: optic nerve findings on initial visit left eye: visual fields on initial visit right eye: visual fields on initial visit left eye: medication history and intolerances at first visit: glaucoma procedures right eye: glaucoma procedures left eye: other eye procedures right eye: other eye procedures left eye: other eye problems right eye: other eye problems left eye: family history: steroids: trauma: asthma: other medical history and problems: PERSON plan: patient left without being seen. likely primary open angle glaucoma right eye based on optical coherence tomography and early humphrey visual field changes.",
"gpt4_summary": "Patient first seen by a specialist for suspected glaucoma. Indications suggest probable primary open angle glaucoma in right eye based on OCT and early visual field changes.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08863",
"image_path": "slo_fundus_08863.jpg",
"filename": "data_08863.npz",
"report": "The patient has moderate normal tension glaucoma in both eyes, with intraocular pressure at 10. No family history of glaucoma was reported. Some long-term progression was noted, especially in the left eye. Condition is stable, presumably due to Dorzolamide treatment, continued twice daily.",
"age": 80.45,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "1. moderate normal tension glaucoma ou - cct (540/559); tmax unknown (10 ou on initial visit); no fhx of glaucoma - hvf with ia os (full od) - some ltf especially in os, but overall likely stable - oct-rnfl 77/75 (sup thin os) - iop 10 ou DATE_TIME on dorzolamide; stable - cont dorzolamide bid ou given likely vascular dysregulation as a component of his disease - continue LOCATION at dinner time instead of bed time right before sleeping (ok per his pcp) given concerns with ocular perfusion 2. pciol ou (sulcus 3 piece iol od nasally displaced) - stable - follow 3. h/o rd os vs tear os? - laser scars seen os - followed by dr. PERSON precautions 4. erm ou with PERSON od - followed by dr. PERSON social/systemic: takes LOCATION; uses PERSON bid rtc DATE_TIME with hvf ou (os first, then od)",
"gpt4_summary": "The patient has moderate normal tension glaucoma in both eyes, with intraocular pressure at 10. No family history of glaucoma was reported. Some long-term progression was noted, especially in the left eye. Condition is stable, presumably due to Dorzolamide treatment, continued twice daily.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08867",
"image_path": "slo_fundus_08867.jpg",
"filename": "data_08867.npz",
"report": "The patient is an open-angle glaucoma suspect due to a visual field defect in the right eye, with high glaucoma risk in both eyes. Currently, no extra intraocular pressure treatment is needed.",
"age": 64.76,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "problem list items addressed this visit neuro and eent open angle with borderline findings and high glaucoma risk in both eyes overview open angle glaucoma suspect based on visual field defect and cdr right eye. previously managed by dr. PERSON. target iop: / , tmax: ( ) / ( ); central corneal thickness: / refractive error: od -5.25 . sphere x / os -4.25 . -0.75 x 130 optic nerve structure and function: paracentral defect right eye. medications and intolerances: was on drops while in LOCATION - stopped here. procedures and complications: none relevant history and problems: current assessment & plan no additional intraocular pressure treatment now. relevant orders humphrey visual field - ou - both eyes (completed) oct, optic nerve - ou - both eyes - cirrus (completed)",
"gpt4_summary": "The patient is an open-angle glaucoma suspect due to a visual field defect in the right eye, with high glaucoma risk in both eyes. Currently, no extra intraocular pressure treatment is needed.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08868",
"image_path": "slo_fundus_08868.jpg",
"filename": "data_08868.npz",
"report": "Patient status post left complete resection of occipital lobe avm, exhibiting recent reading difficulty. No mass effect or enhancement suggesting tumour. Recommended repeat CT scan. No glaucoma mentioned.",
"age": 60.89,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "occipital cortex, but that must be due to loss of afferent radiation fibers that would project to that tissue. in addition, there was volume loss at the left parietal-occipital sulcus, in the region that i was exploring as a potential explanation for the reading difficulty. this region did not enhance, nor was there mass effect, which makes a tumor very unlikely (although, plausibly, still plausible for a low grade glioma or oligodendroglioma). dr. PERSON suggested that this area could have experienced volume loss because of closure of vessels that had communicated with the avm, although this would not explain the recent onset of reading difficulties. given the fairly recent onset of symptoms, dr. PERSON recommended repeat ct with contrast in DATE_TIME, which the patient agreed to do. diagnoses. 1. status post left complete resection of occipital lobe avm (age 20) 2. recent difficulty with reading, ? etiology recommendations. 1. ct of brain with contrast: done 2. repeat ct of brain with contrast in DATE_TIME. patient will obtain cd of early ct scans for comparison PERSON, PERSON, neuro-ophthalmology service ----- i spent a total of DATE_TIME preparing and caring for this patient (face-to-face and non face-to-face); reviewing the ct with the patient before and after my discussion with dr. PERSON; formulating and finalizing the note.]",
"gpt4_summary": "Patient status post left complete resection of occipital lobe avm, exhibiting recent reading difficulty. No mass effect or enhancement suggesting tumour. Recommended repeat CT scan. No glaucoma mentioned.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08870",
"image_path": "slo_fundus_08870.jpg",
"filename": "data_08870.npz",
"report": "The patient has ocular hypertension and some decline in condition while being on 3 glaucoma drops (Combigan, Travatan, Dorzolamide). Despite the inclusion of Travatan, IOP never exceeded 21. Travatan was stopped without issues. Worsening hvfs noted.",
"age": 53.45,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "1. ocular hypertension (cacg s/p lpis ou) with optic nerve PERSON 22/23 or 21 ou per dr. PERSON; had 1 iop reading of 25, DATE_TIME with PERSON, so was sent to PERSON - per review of charts, iops never higher than 21 despite 1st drop added of travatan - stable but some decline PERSON (different machines though) - was on 3 glaucoma drops (combigan and travatan despite tmax 22/23, so travatan stopped DATE_TIME without problems) - worsening hvfs DATE_TIME a. cpm (combigan ou, travatan ou) but add dorzolamide ou bid b. rtc 1-2 weeks pressure check; repeat undilated hvf ou",
"gpt4_summary": "The patient has ocular hypertension and some decline in condition while being on 3 glaucoma drops (Combigan, Travatan, Dorzolamide). Despite the inclusion of Travatan, IOP never exceeded 21. Travatan was stopped without issues. Worsening hvfs noted.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08871",
"image_path": "slo_fundus_08871.jpg",
"filename": "data_08871.npz",
"report": "77 y.o. woman with niddm, afib, wet amd followed by Dr. Identified as a glaucoma suspect based on c/d asymmetry, but has excellent iop and no family history of glaucoma. Possible defects due to amd, not glaucoma. Also has cataract.",
"age": 78.02,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "legally separated",
"note": "77 y.o. woman with niddm, afib on warfarin seen by dr. PERSON DATE_TIME. followed by dr. PERSON for wet amd. \u00ff # wet armd ou - s/p eylea injection ou, most recently DATE_TIME - followed by dr. i PERSON \u00ff # LOCATION -no evidence of diabetic retinopathy -a1c ~6.9, followed at beth israel -stressed importance of bs, bp control \u00ff # glaucoma suspect based on c/d asymmetry os>od - no family history of glaucoma, no trauma - healthy rim ou, good iop ou, relatively low suspicion given excellent iop - cct DATE_TIME DATE_TIME wnl ou DATE_TIME wnl DATE_TIME wnl ou --stable - hvf DATE_TIME od central defects os unreliable, inf defects hvf DATE_TIME more reliable DATE_TIME, od/os with enlarged blind spots. stable overall hvf DATE_TIME od unreliable due to fn error os borderline unreliable due to fn error, possible arcuate defect -observe. iop excellent. vf defects in od and maybe os likely related to amd and not glaucoma. oct has remained stable # combined cataract ou - becoming visually significant, observe for now \u00ff #refractive error - mrx provided last visit fu DATE_TIME, mrx, dilate",
"gpt4_summary": "77 y.o. woman with niddm, afib, wet amd followed by Dr. Identified as a glaucoma suspect based on c/d asymmetry, but has excellent iop and no family history of glaucoma. Possible defects due to amd, not glaucoma. Also has cataract.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08872",
"image_path": "slo_fundus_08872.jpg",
"filename": "data_08872.npz",
"report": "Patient is a 45 year old white, non-hispanic female. She does not have glaucoma. COVID prescreening done.",
"age": 45.43,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "a 45 y.o. white, non-hispanic female with no diagnosis of glaucoma. covid prescreening complete.",
"gpt4_summary": "Patient is a 45 year old white, non-hispanic female. She does not have glaucoma. COVID prescreening done.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08877",
"image_path": "slo_fundus_08877.jpg",
"filename": "data_08877.npz",
"report": "Patient has wet age-related macular degeneration in both eyes, geographic atrophy, poor vision and no indicated glaucoma. Injections and OCT scan also mentioned.",
"age": 83.12,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "History: \u00ff Wet age-related macular degeneration, both eyes \u00ff s/p Intravitreal injection of bevacizumab x 5, right eye s/p Intravitreal injection of afliberceopt x 3, right eye \u00ff s/p Intravitreal injection of bevacizumab x ?, left eye Now with geographic atrophy, poor vision \u00ff s/p Intravitreal injection of ranibizumab # 32, right eye - last DATE \u00ff \u00ff Optical coherence tomography (OCT)\u00ff DATE: \u00ff\u00ff\u00ffRight - Persistent\u00ffsubretinal fluid involving the fovea, pigment epithelial detachments, drusen, CMT = 271\u00ff-> 311\u00ffum \u00ff\u00ff\u00ffLeft - Outer retinal tubulation, no fluid, drusen, central retinal atrophy - stable \u00ff \u00ff Procedure: \u00ff Intravitreal injection of aflibercept # 15 / # 12\u00ffin this series, right eye \u00ff \u00ff Recommend: \u00ff Intravitreal injection of aflibercept, right eye, 4 weeks +OCT OU \u00ff \u00ff PERSON",
"gpt4_summary": "Patient has wet age-related macular degeneration in both eyes, geographic atrophy, poor vision and no indicated glaucoma. Injections and OCT scan also mentioned.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08878",
"image_path": "slo_fundus_08878.jpg",
"filename": "data_08878.npz",
"report": "56 y.o. male is suspected to have glaucoma due to cup/disc (c/d) asymmetry. There is no family history of the illness. The patient's intraocular pressure is controlled. There is also mention of a refractive error.",
"age": 56.24,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "56 y.o. male 1. glaucoma suspect based on c/d asymmetry od>os no family history. tmax: 21,20 cct: cct 573 & 578 (average) hvf full ou oct wnl ou family history: denies race: white optic nerve photos stable ou c/w 2008 iop controlled observe 2. refractive error: mrx given DATE_TIME. floaters no tears/rd rd warnings 6 PERSON check PERSON c Person scribing for dr. PERSON at DATE_TIME on DATE_TIME. i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "56 y.o. male is suspected to have glaucoma due to cup/disc (c/d) asymmetry. There is no family history of the illness. The patient's intraocular pressure is controlled. There is also mention of a refractive error.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08882",
"image_path": "slo_fundus_08882.jpg",
"filename": "data_08882.npz",
"report": "The patient has been diagnosed with glaucoma, with intraocular pressure (IOP) levels noted at 22/19. No previous glaucoma surgery has been conducted. The plan involves starting the patient on Timolol for early damage, particularly in the right eye.",
"age": 73.72,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "# first seen by PERSON on DATE_TIME diagnosis: glaucoma eval based on nct iop 22/19 ttarget: / , tmax: ( ) / ( ) cct: 538 / 543 gonioscopy: refractive error: od -1.25. -0.25. 060 / os -0.50. -0.75. 115 optic nerve: rnfl oct: borderline od ; os nml vf: normal both eyes med intolerances: prior glaucoma surgery: none od / none os other eye surgery: sulcus iol od with iol exchange due to concern for p acnes s/p antibiotic injection / pciol os by PERSON FHx:father (no vision loss or surgery) / steroids: on prednisone for autoimmune pancreatitis & nhl (stopped in DATE_TIME for 6 months) / asthma: no / trauma: none # s/p ce pmhx: autoimmune pancreatitis , NHL , htn, hld, hypothyroid plan: likely early damage od, given iop difference between two eyes and history of multiple eye surgery in od, i recommend we start treated patient agrees start timolol once/day in od only, rba discussed rtc 2-3 mths intraocular pressure, disc photos, dilate diagnosis of glaucoma/glaucoma suspect discussed with patient - review of natural history and management options discussed. importance of lifelong follow up and adherence to treatments discussed in order to lower risk of permanent vision loss/blindness from glaucoma. all questions answered. i spent 45 MINUTES with the patient, more than half of which was spent on counseling and coordination of care for this patient's glaucoma",
"gpt4_summary": "The patient has been diagnosed with glaucoma, with intraocular pressure (IOP) levels noted at 22/19. No previous glaucoma surgery has been conducted. The plan involves starting the patient on Timolol for early damage, particularly in the right eye.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08886",
"image_path": "slo_fundus_08886.jpg",
"filename": "data_08886.npz",
"report": "Patient has cataracts in both eyes and is off glaucoma medications. Restarting Cosopt and Brimonidine to maintain intraocular pressure \u226414 mmHg in both eyes. Not currently using Rhopressa.",
"age": 53.03,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "the patient. 4. cataracts, both eyes -potentially visually significant as of DATE_TIME. 5. social/systemic issues: originally from LOCATION, LOCATION. she has been in the LOCATION for since DATE_TIME. attending's plan: -goal intraocular pressure less than or equal to 14 mmhg, right eye -goal intraocular pressure less than or equal to 14 mmhg, left eye -iop above goal od and above goal os on DATE_TIME off glaucoma medications. -restart cosopt bid ou. -restart brimonidine bid ou. -hold rhopressa qhs ou. -instructions written/typed/printed out for patient (see table/details under patient instructions). -emphasized adherence to medication regimen. -retinal detachment precautions were reviewed with the patient. -preservative-free artificial tears as needed. -rtc in DATE_TIME with iop check, arx/mrx (near/far), bat, optical biometry, and disc photos ou, sooner prn. if iop above goal still, we can try rhopressa at that point. the information above was documented by Person as a scribe for PERSON on DATE_TIME. i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "Patient has cataracts in both eyes and is off glaucoma medications. Restarting Cosopt and Brimonidine to maintain intraocular pressure \u226414 mmHg in both eyes. Not currently using Rhopressa.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08887",
"image_path": "slo_fundus_08887.jpg",
"filename": "data_08887.npz",
"report": "Patient has narrow occludable angle ou, requiring lpi ou. Reviewed risks, benefits of laser surgery & retinal detachment precautions. No asa/blood thinners needed.",
"age": 74.3,
"gender": "female",
"race": "white",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "married or partnered",
"note": "for patient (see table/details under patient instructions). -emphasized adherence to medication regimen. -preservative-free artificial tears as needed. -retinal detachment precautions were reviewed with the patient. -long discussion with patient on DATE_TIME: given narrow occludable angle ou, we will proceed lpi ou. risks, benefits, and alternatives to laser were discussed with the patient, including the potential risk of infection, bleeding, loss of vision, loss of eye, double vision, need for further surgery or laser, retinal detachment, change in glasses and reading glasses. no guarantees given. questions answered. consents signed. no asa/blood thinners implants/special equipment needed -- none preferred anesthesia -- topical diabetic -- DATE_TIME after lpi ou with iop check, gonioscopy, dilation, and disc photos ou, sooner prn. i personally spent DATE_TIME preparing for, caring for the patient (face-to-face and non face-to-face), and finalizing the visit for this patient. the information above was documented by Person as a scribe for PERSON on DATE_TIME. i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow (PERSON, md). i have reviewed the resident/fellow's notes and made any necessary changes. i saw and evaluated this patient and discussed the case as appropriate with the medical student (PERSON). i have reviewed the medical student's notes and made any necessary changes.",
"gpt4_summary": "Patient has narrow occludable angle ou, requiring lpi ou. Reviewed risks, benefits of laser surgery & retinal detachment precautions. No asa/blood thinners needed.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08893",
"image_path": "slo_fundus_08893.jpg",
"filename": "data_08893.npz",
"report": "Possible normal tension glaucoma in female with large eye cups, high cup-to-disc ratio. Paternal cousin & grandfather had glaucoma. Current intraocular pressure normal. Family genetics discussed.",
"age": 26.73,
"gender": "female",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "female with concern regarding possible normal tension glaucoma. she has been noted to have large cups and high cup-to-disc ratio. she has a paternal first cousin with a nonprogressing visual field defect in one of her eyes and is on 'drops' for intraocular pressure control. the cousin was diagnosed at DATE_TIME and has never had 'high' intraocular pressure. her grandfather also had glaucoma and possibly normal tension glaucoma. exam DATE_TIME reveals large cups (cup:disc ratio of 0.7-0.8) with intact rims. the retina is otherwise normal. humphrey visual field testing was normal with full fields and optical coherence tomography is essentially normal with one borderline area superiorly right eye. intraocular pressure was 19 right eye and 17 left eye with central corneal thickness of 496 right eye and 500 left eye . impression: the main finding is large cups which may be normal for her or may be an early indicator of a progressive disease. the most significant family history is the paternal cousin, no other family members have evidence of disease. we discussed the genetics of normal tension glaucoma (patient is a genetic counselor at Institution) including both mendelian forms due to optn or tbk1 mutations and common complex disease. its highly unlikely she carries an optn or tbk1 mutation given her mostly normal exam. we will follow up looking for any clinical indication of progression including repeat humphrey visual field and optical coherence tomography in.",
"gpt4_summary": "Possible normal tension glaucoma in female with large eye cups, high cup-to-disc ratio. Paternal cousin & grandfather had glaucoma. Current intraocular pressure normal. Family genetics discussed.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08894",
"image_path": "slo_fundus_08894.jpg",
"filename": "data_08894.npz",
"report": "The patient has central retinal vein occlusion in right eye and unexplained vision loss, possibly due to traumatic optic neuropathy. Shows symptoms of microvascular disease. No glaucoma mentioned.",
"age": 65.39,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "neuropathy, but was not consistent with her poor visual acuity. ct face and orbits did not show any orbital fracture or evidence of traumatic optic nerve injuery. mri brain with and without contrast showed moderate white matter changes consistent with microvascular disease, but did not reveal an etiologly of her vision URLere was concern for giant cell arteritis, however her esr and crp were normal and her head aches were consistent with her recent head trauma. i discussed my findings of central retinal vein occlusion with the patient, but also my concern that these findings do not adequately explain her vision loss as her macula appears well perfused. despite negative imaging, my leading differential diagnosis would be a traumatic optic neuropathy that is relatively acute given the lack of pallor of her optic nerve. i again emphasized the need for the patient to obtain urgent primary care evaluation for her frequent falls including thorough syncope evaluation and medication review. impression: 1. central retina vein occlusion right eye 2. vision loss right eye not fully explained by #1 3. possible traumatic optic neuropathy 4. recent frequent falls plan: 1. ct face DATE_TIME, mri brain and orbits with and without contrast pending results of above 2. urgent primary care work up for falls 3. follow up with retina specialist for further management of vein occlusion 4. follow up with me in DATE_TIME for repeat exam 5. monocular precautions- patient will change her prescription to polycarbonate lenses this note was prepared with the assistance of laurel tainsh md, ophthalmology resident PERSON, PERSON neuro-ophthalmology LOCATION PHONE_NUMBER fax PHONE_NUMBER",
"gpt4_summary": "The patient has central retinal vein occlusion in right eye and unexplained vision loss, possibly due to traumatic optic neuropathy. Shows symptoms of microvascular disease. No glaucoma mentioned.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08897",
"image_path": "slo_fundus_08897.jpg",
"filename": "data_08897.npz",
"report": "46-year-old female followed up for asthenopia and glaucoma evaluation after a bike accident. No ocular trauma detected but possible post-concussion syndrome noted. She's a glaucoma suspect with increased cup/disc ratio in both eyes. Also has macular drusen in the right eye. Rx updated.",
"age": 46.62,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "46 f for f/u from PERSON ed DATE_TIME with asthenopia; also for glaucoma evaluation. recently with bicycle accident with headstrike DATE_TIME; no ocular trauma seen DATE_TIME. # possible post-concussion syndrome, with acute increased difficulty in compensating for astigmatism and presbyopia. - f/u with pcp # glaucoma suspect with increased cup/disc ratio, both eyes [ fhx: father [ cct: 566,570 [ oct DATE_TIME: full ou [ hvf DATE_TIME: full ou - no intervention required at this time. continue to monitor. # macular drusen, right eye. not visually significant. - discussed not smoking; antioxidants; uv protection - monitor # refractive error (myopic astigmatism and early presbyopia), needs to update glasses. discussed normal effects of presbyopia - new rx given to patient. rtc 1 year, sooner prn i personally spent >DATE_TIME preparing for, caring for the patient (face-to-face and non face-to-face), and finalizing the visit for this patient on DATE_TIME of the visit.",
"gpt4_summary": "46-year-old female followed up for asthenopia and glaucoma evaluation after a bike accident. No ocular trauma detected but possible post-concussion syndrome noted. She's a glaucoma suspect with increased cup/disc ratio in both eyes. Also has macular drusen in the right eye. Rx updated.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08905",
"image_path": "slo_fundus_08905.jpg",
"filename": "data_08905.npz",
"report": "Patient with low risk glaucoma suspect due to increased c:d ratio. Visually significant cataracts present in both eyes, with symptoms including vision deterioration. Patient opted for surgery.",
"age": 79.76,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "# low risk glaucoma suspect due to increased c:d ratio no fhx tmax 19/17 per available epic records cct 595/596 hvf wnl ou oct rnfl shows artifactual changes od (likely due to cataract), wnl os \u00ff\u00ff # visually significant cataracts od>os -pt is symptomatic and has noticed a deterioration in vision in the right eye affecting pt's adl; pt interested in surgery pmhx: niddm (a1c 6.1), htn, hld, gout plan: schedule for ce/iol od gerardo gesualdi has a visually significant cataract in the both eye that is impairing activities of DATE_TIME living and the patient desires surgery the r/b/a were discussed including a potential for loss of vision due to surgical complication including but not limited to infection, hemorrhage, retinal detachment and need to return to or, and benefits of cataract extraction were explained to the patient as was the option of deferring the surgery to DATE_TIME. the patient opted to proceed with surgery and informed consent was obtained. issues related to refractive error and its correction post-op have also been discussed. i have explained that there can be no guarantee of complete spectacle freedom. target: distance lens type: monofocal trauma: no flomax: no guttae: trace pxf: no dm: yes, not on insulin trypan: maybe pupil diameter 6 mm iris hooks/malyugan ring: likely no nuclear disassembly method: stop and chop anesthesia: PERSON aspirin/warfarin: asa right eye first will need to get a scan -- significant difference in axial length i spent DATE_TIME with the patient, more than half of which was spent on counseling and coordination of care for this patient's glaucoma and cataracts",
"gpt4_summary": "Patient with low risk glaucoma suspect due to increased c:d ratio. Visually significant cataracts present in both eyes, with symptoms including vision deterioration. Patient opted for surgery.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08906",
"image_path": "slo_fundus_08906.jpg",
"filename": "data_08906.npz",
"report": "86 y.o. white, non-hispanic female diagnosed with glaucoma. Recommended hygiene: baby shampoo, gel at night if needed.",
"age": 86.52,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "a 86 y.o. white, non-hispanic female was evaluated and diagnosed with glaucoma. hygiene prn. at recommendation given, baby shampoo (not oil), if still sx gel qhs",
"gpt4_summary": "86 y.o. white, non-hispanic female diagnosed with glaucoma. Recommended hygiene: baby shampoo, gel at night if needed.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08907",
"image_path": "slo_fundus_08907.jpg",
"filename": "data_08907.npz",
"report": "The patient has glaucoma of the left eye associated with ocular inflammation in a mild stage. There's a history of uveitic (HSV) glaucoma with recurrences. Timolol is used for treatment.",
"age": 43.63,
"gender": "male",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "visual acuity visual acuity (snellen - linear) right left dist cc 20/20 20/20 correction: glasses tonometry tonometry (applanation, DATE_TIME) right left pressure 20 12 tonometry #2 (applanation, DATE_TIME) right left pressure 17 16 main ophthalmology exam external exam right left external normal normal slit lamp exam right left lids/lashes normal normal conjunctiva/sclera normal normal cornea normal normal anterior chamber normal normal iris normal normal lens 1+ cortical cataract 1+ cortical cataract fundus exam right left vitreous normal normal disc normal normal c/d ratio 0.7 0.7 macula normal normal vessels normal normal periphery normal normal problem list items addressed this visit eye/vision problems glaucoma of left eye associated with ocular inflammation, mild stage overview history of uveitic (hsv) glaucoma, likely LOCATION os, DATE_TIME with recurrence (third episode) cct 540s ou, maximum iop DATE_TIME os, family history neg - episode in DATE_TIME and recurrent episode DATE_TIME with iop elevation and cell - prior surgeries and lasers: none - intolerance to medications: none - hvf DATE_TIME and DATE_TIME: full ou - oct rnfl with ?worsening inf thinning os flare up DATE_TIME, improved on pred, valtrex and glaucoma meds --> off pred now iop better, but still symmetric with od so will keep on timolol os given recurrences though only using DATE_TIME current assessment & plan iop controlled currently on no drops testing had been normal with no sign of glaucomatous defects patient with cupping though ou and needs DATE_TIME testing follow-up in DATE_TIME iop check PERSON, md DATE_TIME",
"gpt4_summary": "The patient has glaucoma of the left eye associated with ocular inflammation in a mild stage. There's a history of uveitic (HSV) glaucoma with recurrences. Timolol is used for treatment.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08911",
"image_path": "slo_fundus_08911.jpg",
"filename": "data_08911.npz",
"report": "72 y.o. white, non-hispanic female diagnosed with glaucoma. Underwent covid phone screening.",
"age": 72.21,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "a 72 y.o. white, non-hispanic female was evaluated and diagnosed with glaucoma. covid phone screening",
"gpt4_summary": "72 y.o. white, non-hispanic female diagnosed with glaucoma. Underwent covid phone screening.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08912",
"image_path": "slo_fundus_08912.jpg",
"filename": "data_08912.npz",
"report": "75 y.o. white, non-hispanic female diagnosed with glaucoma.",
"age": 75.75,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "a 75 y.o. white, non-hispanic female was evaluated and diagnosed with glaucoma.",
"gpt4_summary": "75 y.o. white, non-hispanic female diagnosed with glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08916",
"image_path": "slo_fundus_08916.jpg",
"filename": "data_08916.npz",
"report": "Patient suspect for glaucoma with low intraocular pressure. Normal optic nerve findings. Enlarged blind spot, retinal scar in right eye, normal fields in left. No family history of glaucoma. Other conditions: cutaneous lupus. Plan: regular monitoring, occasional hydrocortisone use.\n",
"age": 45.67,
"gender": "female",
"race": "asian",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "single",
"note": "first seen by dr. PERSON on DATE_TIME, patient of nz diagnosis: glaucoma suspect, low iop, LOCATION near disc od accounting for vf loss \u00ff target iop: 23 / 23,\u00ff tmax: 18 ( ) / 18 ( ) \u00ff central corneal thickness: 623 / 625 \u00ff gonioscopy: \u00ff refractive error: od . . / os . . \u00ff optic nerve findings on initial visit right eye: large normal optic nerve findings on initial visit left eye: large normal \u00ff visual fields on initial visit right eye: enlarged blind spot, retinal scar visual fields on initial visit left eye: normal \u00ff medication history and intolerances at first visit:\u00ff \u00ff glaucoma procedures right eye: glaucoma procedures left eye: \u00ff other eye procedures right eye: other eye procedures left eye: \u00ff other eye problems right eye: rpe scar near disc od accounting for vf loss other eye problems left eye: \u00ff \u00ff family history: none, daughter has large cup:disc at DATE_TIME noted steroids: hydrocortizone cream (rare use) trauma: asthma: \u00ff other medical history and problems:\u00ff \u00ff cutaneous lupus (briefly was on plaquenil) \u00ff plan: \u00ff - humphrey visual field and optical coherence tomography stable DATE_TIME - iop ok; only very rare use of hydrocortisone cream (<1/mo) - otc readers ok; if unhappy can call optom - return to clinic DATE_TIME with optical coherence tomography and humphrey visual field ou",
"gpt4_summary": "Patient suspect for glaucoma with low intraocular pressure. Normal optic nerve findings. Enlarged blind spot, retinal scar in right eye, normal fields in left. No family history of glaucoma. Other conditions: cutaneous lupus. Plan: regular monitoring, occasional hydrocortisone use.\n",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08919",
"image_path": "slo_fundus_08919.jpg",
"filename": "data_08919.npz",
"report": "The patient has chronic problems that threaten vision/neurological function & health. High risk of morbidity due to stroke. No mention of glaucoma.",
"age": 43.67,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "return to neuro-ophth as needed PERSON, PERSON, neuro-ophthalmology service (this note was prepared with the assistance of dr. PERSON.) ----- [administrative formulation. my impression of this case is based upon an assessment of the the patient's chronic problems as detailed under 'diagnoses' above that pose a threat to vision / neurological function or systemic health. my assessment of this case also included review of the following data: 1) results of tests and outside documents (specifically: a review of prior external notes (dr. PERSON); review of unique test results (including those described under 'ancillary studies' above); ordering unique tests; assessment requiring independent historian - his wife); 2) independent interpretation of tests performed by PERSON (mri and ct) ; and with respect to management, this patient has a high risk of morbidity related to his stroke. ]",
"gpt4_summary": "The patient has chronic problems that threaten vision/neurological function & health. High risk of morbidity due to stroke. No mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08922",
"image_path": "slo_fundus_08922.jpg",
"filename": "data_08922.npz",
"report": "The patient is a 66-year-old male with ocular hypertension in both eyes, interested in participating in a coast trial. No glaucoma medication intolerances. No thinning in retinal nerve fibre layer in either eye. Other medical history includes prostate cancer, hypertension, hyperlipidemia, and asthma. Mild cataracts in both eyes, not visually significant. Plan includes selective laser trabeculoplasty.",
"age": 67.02,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "first seen by dr. PERSON on DATE_TIME (previously followed by dr. PERSON) glaucoma medication intolerances: none target iop: DATE_TIME, tmax: 28 / 27 central corneal thickness: 533 / 533 gonioscopy: c30b 2+ ou retinal nerve fiber layer, right eye: no thinning retinal nerve fiber layer, left eye: no thinning visual fields, right eye: full visual fields, left eye: full family history: father in setting of injury, mother, borther steroids: none trauma: none asthma/copd: asthma other medical history and problems: prostate cancer s/p prostatectomy, htn, hld assessment/plan: 66 y.o. male security guard # ocular hypertension, both eyes - iop too high ou, vf and oct stable - discussed drops vs selective laser trabeculoplasty, interested in participating in coast trial - i discussed the risks/benefits/alternatives to bilateral eye selective laser trabeculoplasty including but not limited to the following: prolonged inflammation, acute eye pressure elevation, and inadequate eye pressure lowering that requires further treatment. after this discussion, the patient elected to proceed. - return in DATE_TIME for iop check, vf sita standard, biometry, and slt ou as per coast trial protocol # exophoria - no diplopia, good control, likely longstanding, monitor # cataract, both eyes - mild, not visually significant, monitor # refractive error, contact lens wear - next appointment with PERSON DATE_TIME - next appointment with dr. lo DATE_TIME PERSON, md",
"gpt4_summary": "The patient is a 66-year-old male with ocular hypertension in both eyes, interested in participating in a coast trial. No glaucoma medication intolerances. No thinning in retinal nerve fibre layer in either eye. Other medical history includes prostate cancer, hypertension, hyperlipidemia, and asthma. Mild cataracts in both eyes, not visually significant. Plan includes selective laser trabeculoplasty.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08928",
"image_path": "slo_fundus_08928.jpg",
"filename": "data_08928.npz",
"report": "Patient has glaucoma and is on medication. Intraocular pressure goals: \u226417 mmhg for both eyes. She's advised to pause Cosopt and Brimonidine, and resume Latanoprost. Possible revision of Xen gel stent if pressure exceeds goals.\n",
"age": 56.31,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "married or partnered",
"note": "shared patient with dr. PERSON. patient originally from LOCATION; she understands NRP fairly well. she has been accompanied by her fully bilingual daughter and her son. patient's daughter is best contact for appointments: roseance phanor, tel. PHONE_NUMBER (updated phone number DATE_TIME). PERSON also comes to some appointments. attending's plan: -goal intraocular pressure less than or equal to 17 mmhg, right eye. -goal intraocular pressure less than or equal to 17 mmhg, left eye. -iop at goal od and at goal os on DATE_TIME s/p phaco/xen os s/p needling at the slit lamp (failed) and off glaucoma medications. -hold cosopt bid ou. -hold brimonidine tid ou. -restart latanoprost qhs ou => sample given on DATE_TIME. -instructions written out for patient (see table/details under patient instructions). -emphasized adherence to medication regimen. -preservative-free artificial tears as needed. -follow-up with dr. PERSON for retina care. -long discussion with patient in english/french on DATE_TIME: we proceeded with phaco/xen gel stent os. -rtc in DATE_TIME with iop check and disc photos ou, sooner prn. if iop above goal os in future, consider revision of xen gel stent in or. the information above was documented by PERSON as a scribe for PERSON on DATE_TIME. i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "Patient has glaucoma and is on medication. Intraocular pressure goals: \u226417 mmhg for both eyes. She's advised to pause Cosopt and Brimonidine, and resume Latanoprost. Possible revision of Xen gel stent if pressure exceeds goals.\n",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08929",
"image_path": "slo_fundus_08929.jpg",
"filename": "data_08929.npz",
"report": "Patient has type II diabetes, good visual acuity, right upper eyelid cystic lesion, blepharitis, high c/d ratio in both eyes, and history of trauma in right eye. Noted RNFL thinning in the right eye. No IOP elevations, though family history of glaucoma. Possible low-tension glaucoma. Reevaluation in 6 months.",
"age": 90.99,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "imp: dmii without diabetic PERSON, with good va cystic lesion rul blepharitis ou inc c/d od>os, hx trauma od - oct rnfl DATE_TIME: od sup thinning PERSON, PERSON--stable; hvf with arcuate changes od>os - + fhx glaucoma (mother) - no iop elevation -cct 614/582 rnfl thinning likely post traumatic from childhood, but could represent low tension glaucoma pt wishes to rv here in 6 mo--will repeat hvf and oct of rnfl then",
"gpt4_summary": "Patient has type II diabetes, good visual acuity, right upper eyelid cystic lesion, blepharitis, high c/d ratio in both eyes, and history of trauma in right eye. Noted RNFL thinning in the right eye. No IOP elevations, though family history of glaucoma. Possible low-tension glaucoma. Reevaluation in 6 months.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08930",
"image_path": "slo_fundus_08930.jpg",
"filename": "data_08930.npz",
"report": "Patient experienced sudden vision loss in right eye, characterized by a 'black line' and increasing blurry vision. Oct and fluorescein angiogram showed 'cotton wool spot', cellular debris, potentially from inflammation/infection. Right optic nerve appeared normal. Diagnosis unclear; considering lebers hereditary optic neuropathy. Further genetic, serological testing recommended. No sign of glaucoma.",
"age": 29.79,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "formulation: this patient experienced sudden, painless loss of vision, like a 'black line' just below fixation in his right eye. he was seen by an ophthalmologist who performed oct and fluorescein angiogram, and he diagnosed a 'cotton wool spot'. since that exam, the size of the black line has stayed the same but an area of blurry vision in the inferior quadrant has progressed. my exam showed an abnormal visual field od, with a relatively dense, inferior central-cecal defect combined with a broader inferior arcuate defect. the fundus exam showed a moderate dense superficial retinal abnormality in the proximal superior arcuate region, which by oct was irregular and thus not consistent with a myelinated nerve fiber defect (which was my initial inclination). the oct also showed cellular debris above and around the lesion, which suggests an inflammatory or infectious etiology. notably, there were no vitreous cells on slit lamp exam. using direct ophthalmoscopy, i perceived very fine telangiectatic peripapillary vessels only in the right eye. both optic nerves appeared normal. i do not have a clear explanation for the visual loss. i am considering lebers hereditary optic neuropathy given his gender/age, the central-cecal like field defect and the possible telangiectasias. for this reason, i recommended lhon genetic testing, given the availability of a possible therapy. however, this diagnosis does not explain the white retinal lesion and seeming cellular reaction. to address this abnormality, which is likely the important clue to the diagnosis, i will confer with dr. PERSON, and hopefully obtain recommendations for serological testing which we can perform DATE_TIME. impression: 1. inferior visual loss od, ? etiology recommendations: 1. follow-up neuro-ophthalmic examination DATE_TIME (i devoted DATE_TIME to the diagnosis and discussion of management.)",
"gpt4_summary": "Patient experienced sudden vision loss in right eye, characterized by a 'black line' and increasing blurry vision. Oct and fluorescein angiogram showed 'cotton wool spot', cellular debris, potentially from inflammation/infection. Right optic nerve appeared normal. Diagnosis unclear; considering lebers hereditary optic neuropathy. Further genetic, serological testing recommended. No sign of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08931",
"image_path": "slo_fundus_08931.jpg",
"filename": "data_08931.npz",
"report": "The patient is a moderate glaucoma suspect with mild cdr asymmetry. Pachymetry (561/547) and Tmax (15/13) noted. A relative has glaucoma. Nasal step discovered that may suggest early glaucoma. Has an early cataract and eyelid conditions.",
"age": 61.76,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "?- glaucoma suspect (moderate) with mild cdr assymetry od > os - pachymetry (561/547); tmax (15/13); PERSON of glaucoma (sister uses PERSON) - hvf with ? early PERSON nasal step od that may be repeatable compared to DATE_TIME with dr. PERSON; full DATE_TIME (47/51) global thinning ou ?- there is poor structure-function correlation and i suspect this is more likely a congenital anomaly and less likely glaucoma - tg = mid teens ou; at goal ou plan: - follow without PERSON for now - reassured patient that tonometer tips are sufficiently sterilized prior to checking iop with LOCATION's solution ? # early cataract ou - not visually significant - follow - chalazion of eyelids, blepharitis plan: pt saw dr. PERSON before. ? social/systemic: hcv treated with sovaldi, htn, hypothyroid; pt was seeing dr. song before. pt has a remote fhx of rp. ? rtc DATE_TIME for iop, NRP and dp's ou. PERSON scribing for dr. PERSON (DATE_TIME, DATE_TIME) i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "The patient is a moderate glaucoma suspect with mild cdr asymmetry. Pachymetry (561/547) and Tmax (15/13) noted. A relative has glaucoma. Nasal step discovered that may suggest early glaucoma. Has an early cataract and eyelid conditions.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08934",
"image_path": "slo_fundus_08934.jpg",
"filename": "data_08934.npz",
"report": "Patient referred for glaucoma monitoring as a glaucoma suspect with increased cup/disc ratio in both eyes. No intervention required, continue to monitor.",
"age": 73.27,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "DATE_TIME PERSON, PERSON charles street boston ma 02114 patient: PERSON a kulash mr number: NUMBER date of birth: DATE_TIME date of visit: DATE_TIME dear dr. PERSON: thank you for referring PERSON to me for evaluation. below are the relevant portions of the exam, along with my assessment and plan of care. vision readings for this visit: va distance LOCATION distance cc va near LOCATION near cc iop right 20/150 16 left 20/70-2 15 assessment and plan: 73 m hx htn last cos visit with PERSON in DATE_TIME. referred back by PERSON for glaucoma monitoring. # glaucoma suspect with increased cup/disc ratio, both eyes [ fhx: no [ cct: 592,575 [ oct DATE_TIME: full ou [ hvf DATE_TIME: central defect od, full os - no intervention required at this time. continue to monitor. # s/p cataract surgery, both eyes, doing well # nonexudative age-related macular degeneration, both eyes - f/u with PERSON, next appt DATE_TIME # refractive error, doing well with current glasses. rtc 1 year, sooner prn if you have questions, please do not hesitate to call me. i look forward to following PERSON along with you. sincerely, , PERSON beverly woo, md",
"gpt4_summary": "Patient referred for glaucoma monitoring as a glaucoma suspect with increased cup/disc ratio in both eyes. No intervention required, continue to monitor.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08936",
"image_path": "slo_fundus_08936.jpg",
"filename": "data_08936.npz",
"report": "The patient underwent phaco/pciol on both eyes and yag capsulotomy to improve vision. Glaucoma is stable. Patient unhappy with blepharoplasty ou results. Follow-ups required for moderate progression risk. Prescription managed.\n",
"age": 64.32,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "if she would like second opinion) for eyelid care. -long discussion with patient on DATE_TIME: given patient amenable and wish for better vision os>od, we proceeded with phaco/pciol os first on DATE_TIME. -i referred her to dr. PERSON on DATE_TIME for refractive care. -mrx given to patient at their request on DATE_TIME and DATE_TIME. -long discussion with patient on DATE_TIME: given visually-significant cataract od that has worsened in DATE_TIME, we proceeded with complex phaco/pciol od (attending case at patient's request) on DATE_TIME. -long discussion with patient on DATE_TIME: given that patient is bothered by pco od, we proceeded with yag capsulotomy od on DATE_TIME. -long discussion with patient on DATE_TIME: i discussed patient's great visual acuity ou and stable hvf, oct, and iop, which indicates stable glaucoma (i.e., 1 stable chronic illness). we also had a long discussion about her recent blepharoplasty ou, which looks good but patient is unhappy with the result of her right eye. i encouraged her to either see dr. PERSON sooner or meet with dr. PERSON for second opinion. importance of follow-up explained to patient given moderate risk of progression without care. prescription drug management was performed. -rtc in DATE_TIME with iop check, hvf (with coaching), dilation, and disc photos ou, sooner prn. i personally spent DATE_TIME preparing for, caring for the patient (face-to-face and non face-to-face), and finalizing the visit for this patient. the information above was documented by Person as a scribe for PERSON on DATE_TIME. i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "The patient underwent phaco/pciol on both eyes and yag capsulotomy to improve vision. Glaucoma is stable. Patient unhappy with blepharoplasty ou results. Follow-ups required for moderate progression risk. Prescription managed.\n",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08937",
"image_path": "slo_fundus_08937.jpg",
"filename": "data_08937.npz",
"report": "Patient has history of being a glaucoma suspect with stable condition. Also has cataracts, mild ptosis, and refractive error. Plans to review yearly.",
"age": 80.52,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "imp: history glaucoma suspect ou; stable hvf and oct cataract ou; asymptomatic mild PERSON ou mild ptosis ou (levator dehisc) refr error plan: yrly with hvf and oct of rnfl and PERSON (mostly wears ctls)",
"gpt4_summary": "Patient has history of being a glaucoma suspect with stable condition. Also has cataracts, mild ptosis, and refractive error. Plans to review yearly.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08938",
"image_path": "slo_fundus_08938.jpg",
"filename": "data_08938.npz",
"report": "54-year-old male patient has ocular hypertension and is on medication (Latanoprost and formerly Betoptic) - IOP at 25/23. No glaucoma detected, but shows temporal thinning. Also has mild myopia, presbyopia, drusen, epiretinal membrane, and non-significant cataracts.",
"age": 54.41,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "54\u00ffyo old male here for DATE_TIME eye exam: \u00ff\u00ff 1. ocular hypetension on meds (latanoprost, betoptic for DATE_TIME, since his 30s) though questionable compliance stopped betoptic DATE_TIME, here for iop check iop today 25/23 (DATE_TIME) \u00ff\u00ff hvf DATE_TIME: full, reliable hvf DATE_TIME: full, reliable hvf DATE_TIME: full ou, reliable DATE_TIME: temporal thinning ou, expected with eccentric cup thick cornea (pachy 600s per outside records) oct rnfl DATE_TIME: normal ou oct rnfl DATE_TIME: normal ou oct rnfl DATE_TIME: normal ou \u00ff\u00ff rec: - cont latanoprost qhs ou - resume timolol xe ou - return DATE_TIME, iop check \u00ff 2. mild myopic correction and presbyopia does not want glasses rx \u00ff\u00ff 3. rpe changes, drusen od, epiretinal membrane os vision good oct macula DATE_TIME: PERSON, very few drusen erm os, mild extrafoveal wrinkling monitor \u00ff\u00ff 4. cataracts ou not visually significant, monitor",
"gpt4_summary": "54-year-old male patient has ocular hypertension and is on medication (Latanoprost and formerly Betoptic) - IOP at 25/23. No glaucoma detected, but shows temporal thinning. Also has mild myopia, presbyopia, drusen, epiretinal membrane, and non-significant cataracts.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08939",
"image_path": "slo_fundus_08939.jpg",
"filename": "data_08939.npz",
"report": "56 y.o. male suspected of having glaucoma due to increased c:d ratio. IOP controlled, some borderline thinning OD, will need follow-up in 6 months.",
"age": 56.09,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "56 y.o. male records reviewed from dr. PERSON 1. glaucoma suspect ou based on increased c:d ratio ou and + pxf os fhx negative hvf full ou oct/ borderline sup thinning od, wnl os; normal ganglion cell analysis ou dp DATE_TIME iop controlled ou observe discussed risk of glaucoma and need for f/u 2. re - cpm with otc readers, inc to +2.00 prn for small print f/u 6 mo check iop, gonio and cct ou",
"gpt4_summary": "56 y.o. male suspected of having glaucoma due to increased c:d ratio. IOP controlled, some borderline thinning OD, will need follow-up in 6 months.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08947",
"image_path": "slo_fundus_08947.jpg",
"filename": "data_08947.npz",
"report": "The patient is a male suspect of low tension glaucoma with risks due to c/d asymmetry, age, and race. They have a thin temporal ou and gcl, more so in the right eye. They also have mild cataracts, hyperopia with presbyopia, and seasonal allergies. No family history of glaucoma or anemia is reported. The patient needs follow-up for glaucoma and transfer of care to a specialist.",
"age": 55.3,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "PERSON is a DATE_TIME. male low tension glaucoma suspect risks include: c/d asymm, age, race. DATE_TIME) rnfl thin temporal ou. gcl thin od > os. thin gcl ou. PERSON -4 ou. hvf 24-2 (DATE_TIME) watch inferior, low reliability od, watch superior, low reliability; increase fixsation os -- repeat next visit low reliability due to fleeting views during hvf pt reports no fhx of glaucoma or anemia pt denies h/o transfusion, trauma, or anemia transfer of care to glaucoma specialist in DATE_TIME hyperopia with presbyopia ou, astigmatism os gave rx mild cataracts ou observe, not visually significant seasonal allergies gave pt seasonal allergy handout recommend at's prn, allergy PERSON, and allergy testing avoid heat/rubbing/allergens avoid visine and other medications that 'get the red out' avoid flonase and other steroidal medications avoid decongestant 'd' variants of allergy meds f/u in DATE_TIME for glaucoma, transfer of care; repeat hvf 24-2,",
"gpt4_summary": "The patient is a male suspect of low tension glaucoma with risks due to c/d asymmetry, age, and race. They have a thin temporal ou and gcl, more so in the right eye. They also have mild cataracts, hyperopia with presbyopia, and seasonal allergies. No family history of glaucoma or anemia is reported. The patient needs follow-up for glaucoma and transfer of care to a specialist.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08950",
"image_path": "slo_fundus_08950.jpg",
"filename": "data_08950.npz",
"report": "The 89-year-old patient has Fuchs corneal dystrophy and open angle glaucoma, with an elevated interoccular pressure in her left eye, possibly due to a steroid response. She's on medication for the glaucoma.",
"age": 89.45,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "89 y.o. woman 1. fuchs corneal dystrophy os>od os: previously, pachy os: 650 and od: 630 \u00ffs/p dmek DATE_TIME os (dr. PERSON) graft attached and clear s/p trauma with towel on DATE_TIME, epithelial defect resolved > followed by PERSON, missed her DATE_TIME > consider switching to lotemax daily os due to steroid response. will talk to dr. PERSON \u00ff 2. open angle glaucoma ou -continue PERSON bid in both eyes -- diagnosed DATE_TIME, only has used this medication during this time >tcurrent: 17/26 >tmax: unknown >tgoal: >c/d ratio: 0.5/0.6 >gonio: open ou DATE_TIME >cct: >oct: DATE_TIME with full rims ou DATE_TIME wnl ou >hvf: od 7/11 fl, os 5/11 fl, od with ? nasal step, os with central scattered defects with unclear pattern >family history: >race: NRP >optic nerve photos: >> iop elevated os, using pf DATE_TIME in that eye, ? steroid response >> continue PERSON bid ou add alphagan bid os >> iop check with dr. PERSONE. if iop ok, fu with me DATE_TIME. pseudophakia ou -s/p capsulotomy ou, visual axis clear ou -monitor for now \u00ff\u00ff 4. refractive error ou - continue current glasses \u00ff 5. detaching posterior LOCATION face ou -no macular traction on DATE_TIME -rd precautions reviewed \u00ff 6. des os>od - plugs and ats \u00ff \u00ff",
"gpt4_summary": "The 89-year-old patient has Fuchs corneal dystrophy and open angle glaucoma, with an elevated interoccular pressure in her left eye, possibly due to a steroid response. She's on medication for the glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08952",
"image_path": "slo_fundus_08952.jpg",
"filename": "data_08952.npz",
"report": "The note does not provide details regarding the presence of glaucoma. It mentions normal orders, an ambulatory visit, and the patient has allergies, lactose intolerance, and chest pain.",
"age": 35.25,
"gender": "female",
"race": "white",
"ethnicity": "hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "directions: not available; details: not available; date: DATE_TIME LOCATION pawar DATE_TIME needs PERSON. metal med transfer process. your orders normal orders this visit ambulatory - ou - both eyes oct, optic nerve - ou - both eyes - condition list as of DATE_TIME seasonal allergic rhinitis lactose intolerance chest pain annual physical exam results summary immunizations administered on date of encounter - DATE_TIME none",
"gpt4_summary": "The note does not provide details regarding the presence of glaucoma. It mentions normal orders, an ambulatory visit, and the patient has allergies, lactose intolerance, and chest pain.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08954",
"image_path": "slo_fundus_08954.jpg",
"filename": "data_08954.npz",
"report": "Patient has potential glaucoma and left eye trauma or possible amblyopia. Advised to start latanoprost, increase smoking cessation. Soft drusen increase observed.",
"age": 73.08,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "od left before md exam DATE_TIME. left message about importance of starting latanoprost to prevent blindness, will refer to glaucoma service 5. left eye trauma vs. possible amblyopia os at DATE_TIME, pencil poked os. ever since, left eye bcva was 20/40. denies patching. 6. soft drusen os >> counseled re importance of smoking cessation. areds 2 advised >> retina consultation for increase in number and size of soft drusen >> saw dr. PERSON DATE_TIME. erm od with PERSON od>os -stable",
"gpt4_summary": "Patient has potential glaucoma and left eye trauma or possible amblyopia. Advised to start latanoprost, increase smoking cessation. Soft drusen increase observed.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08955",
"image_path": "slo_fundus_08955.jpg",
"filename": "data_08955.npz",
"report": "Imp: Cupping in both eyes, glaucoma suspected. However, low eye pressure, normal field of vision & OCT test result. Mild cataracts & refractive error present.",
"age": 71.53,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "Imp: cupping ou, susp. for glaucoma; but low pressure, thick pachymetry, and normal hvf and oct normal (and stable) Mild cataract ou refr error Plan: rx=m glasses RTC 1 yr yrly w hvf and oct",
"gpt4_summary": "Imp: Cupping in both eyes, glaucoma suspected. However, low eye pressure, normal field of vision & OCT test result. Mild cataracts & refractive error present.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08961",
"image_path": "slo_fundus_08961.jpg",
"filename": "data_08961.npz",
"report": "The patient has a history of ocular hypertension and recurrent cme. There was a past instance of blunt trauma to the left eye. She's under monitoring without IOP medication. Glaucoma procedures have been performed on both eyes.",
"age": 67.38,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "first seen by Person on DATE_TIME. she has had a crvo os since DATE_TIME and sees dr. PERSON for recurrent cme. she had ocular hypertension on DATE_TIME. diagnosis: history of ocular hypertension target iop: / , tmax: ( ) / ( ) central corneal thickness: 509 / 540 gonioscopy: refractive error: od +0.75 . DATE_TIME . 088 / os -0.50 . -1.00 . 080 optic nerve/rnfl findings on baseline visit right eye (DATE_TIME): 0.3, full optic nerve/rnfl findings on baseline visit left eye (DATE_TIME): 0.3, borderline superior thinning visual fields on baseline visit right eye (DATE_TIME): full visual fields on baseline visit left eye (DATE_TIME): non-specific defects medication history at first visit: none medication intolerances: glaucoma procedures right eye: glaucoma procedures left eye: other eye procedures right eye: other eye procedures left eye: anti-vegf other eye problems right eye: other eye problems left eye: PERSON family history: no steroids: no trauma: blunt trauma left eye asthma: no other medical history and problems: assessment: 1. history of ocular hypertension -first episode of high iop was on DATE_TIME, stable since then -dilated DATE_TIME, did not get to gonio -testing okay so far, keep an eye on the left superior rnfl 2. PERSON os -initially diagnosed in DATE_TIME cme, getting injections with dr. PERSON plan: -monitor off of iop meds -will follow-up with a gonio on the next visit rtc in DATE_TIME for iop, LOCATION, gonio",
"gpt4_summary": "The patient has a history of ocular hypertension and recurrent cme. There was a past instance of blunt trauma to the left eye. She's under monitoring without IOP medication. Glaucoma procedures have been performed on both eyes.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08966",
"image_path": "slo_fundus_08966.jpg",
"filename": "data_08966.npz",
"report": "The patient suffers from arthritis and hypercholesterolemia, takes meclizine, simvastatin, and Ambien, and has received a visual field test. There is no mention of glaucoma.",
"age": 79.25,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "for pain (specific location in comments). meclizine hcl (meclizine oral) (taking) take 3 mg by mouth. simvastatin (zocor) 20 mg tablet (taking) take 20 mg by mouth nightly. PERSON (ambien) 5 mg tablet (taking) take 5 mg by mouth nightly as needed for sleep. your orders normal orders this visit humphrey visual field - ou - both eyes oct, optic nerve - ou - both eyes - cirrus condition list as of DATE_TIME arthritis hypercholesterolemia results",
"gpt4_summary": "The patient suffers from arthritis and hypercholesterolemia, takes meclizine, simvastatin, and Ambien, and has received a visual field test. There is no mention of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08968",
"image_path": "slo_fundus_08968.jpg",
"filename": "data_08968.npz",
"report": "The clinical note indicates a patient with chronic problems impacting vision/neurological function. Specific tests, assessments, and communication regarding management suggest a moderate risk of morbidity. Glaucoma not mentioned.",
"age": 37.84,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "single",
"note": "yanna (LOCATION) NRP PERSON) ----- [administrative formulation. my impression of this case is based upon an assessment of the the patient's chronic problems as detailed under 'diagnoses' above that pose a threat to vision / neurological function. my assessment of this case also included review of the following data: oct, hvf, mri 1) results of tests and outside documents (specifically: a review of prior external notes; review of unique test results (including those described under 'ancillary studies' above); ordering unique tests; assessment requiring independent historian); 2) independent interpretation of tests performed by PERSON PERSON plotkin 3) discussion or communication or management with dr. PERSON with respect to management, this patient has a moderate risk of morbidity related to treatment limited by social determinants or health.",
"gpt4_summary": "The clinical note indicates a patient with chronic problems impacting vision/neurological function. Specific tests, assessments, and communication regarding management suggest a moderate risk of morbidity. Glaucoma not mentioned.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08970",
"image_path": "slo_fundus_08970.jpg",
"filename": "data_08970.npz",
"report": "Patient's current medication includes aspirin, atenolol, multivitamin, omeprazole, simvastatin, and triamcinolone acetonide. Diagnosed with glaucoma and other conditions like menopause, hypercholesterolemia, and osteoporosis.",
"age": 73.93,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "current medications aspirin 81 mg chewable tablet (taking) dose: not available; form: not available; route: PERSON; frequency: qd; directions: not available; details: dispense: tablet(s); date: DATE_TIME akshay bhosale DATE_TIME needs PERSON. metal med transfer process. atenolol (tenormin) 25 mg tablet (taking) take 0.5 tablets by mouth DATE_TIME. akshay bhosale DATE_TIME metal med transfer process multivitamin oral (taking) dose: not available; form: not available; route: PERSON; frequency: not available; directions: not available; details: not available; date: DATE_TIME akshay bhosale DATE_TIME needs PERSON. metal med transfer process. omeprazole (prilosec) 20 mg capsule (taking) take 1 capsule by mouth DATE_TIME. akshay bhosale DATE_TIME metal med transfer process simvastatin (zocor) 5 mg tablet (taking) take 1 tablet by mouth DATE_TIME. PERSON bhosale DATE_TIME metal med transfer process triamcinolone acetonide 0.1 % cream (taking) apply 1 application topically 2 (two) times a day. akshay bhosale DATE_TIME metal med transfer process your orders normal orders this visit oct, optic nerve - ou - both eyes condition list as of DATE_TIME menopause present hemorrhoids hypercholesterolemia hypertensive disorder glaucoma vitamin d deficiency gastroesophageal reflux disease osteoporosis actinic keratosis basal cell carcinoma of skin knee pain arthritis healthcare maintenance hx of colonic polyps obesity results summary immunizations administered on date of encounter - DATE_TIME none",
"gpt4_summary": "Patient's current medication includes aspirin, atenolol, multivitamin, omeprazole, simvastatin, and triamcinolone acetonide. Diagnosed with glaucoma and other conditions like menopause, hypercholesterolemia, and osteoporosis.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08972",
"image_path": "slo_fundus_08972.jpg",
"filename": "data_08972.npz",
"report": "The clinical note indicates a change in the patient's eye drop treatment. The prescription for latanoprost and dorzolamide has been ceased. The text does not state explicitly about the presence of glaucoma.",
"age": 81.26,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "medication route frequency latanoprost* (teal) stop dorzolamide& (orange) the left eye 3x/day rhopressa (white) stop LOCATION (rhopressa-latanoprost) (white) both eyes DATE_TIME * some medications that may be prescribed in lieu of this medication include: latanoprost, xalatan, travatan z, travaprost, LOCATION, LOCATION, LOCATION/tafluprost (preservative-free). & some medications that may be prescribed in lieu of this medication include: dorzolamide, trusopt, PERSON, brinzolamide. always wait DATE_TIME (by the clock) in between eye drops. please bring this to your next visit. for routine questions, please call PHONE_NUMBER (LOCATION, ask for glaucoma department) or PHONE_NUMBER (longwood). for emergencies, please call PHONE_NUMBER and ask for the glaucoma physician on-call.",
"gpt4_summary": "The clinical note indicates a change in the patient's eye drop treatment. The prescription for latanoprost and dorzolamide has been ceased. The text does not state explicitly about the presence of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08973",
"image_path": "slo_fundus_08973.jpg",
"filename": "data_08973.npz",
"report": "The 62-year-old male patient is suspected to have glaucoma due to an increased c:d ratio; he has a controlled eye pressure. He also has a nuclear cataract in the right eye, notably worse than the left. He suffers from blurry vision and struggles with night driving. After discussing options: updating glasses or cataract surgery with an intraocular lens implant, he decided on surgery. Risks were discussed and reviewed.",
"age": 62.88,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "62 y.o. male 1. glaucoma suspect based on inc c:d ratio ou family history: negative cct: 578/573, average ou hvf full ou dp stable ou c/w 2012 oct wnl ou iop controlled ou observe 2. nuc cataract (od>os). myopic shift od pt bothered by blurry vision od at distance trouble with night driving discussed options of updating glasses vs ce/iol od he wants to proceed with ce/iol od at this time risks, benefits, and alternatives to surgery were discussed with the patient, including the potential risk of infection, bleeding, loss of vision, loss of eye, double vision, need for further surgery or laser, retinal detachment, change in glasses and reading glasses. no guarantees given. questions answered. refractive target options discussed. pt wants to aim distance with monofocal lens. + baby asa, cpm no flomax/tamsulosin/alpha blockers cat surgery od",
"gpt4_summary": "The 62-year-old male patient is suspected to have glaucoma due to an increased c:d ratio; he has a controlled eye pressure. He also has a nuclear cataract in the right eye, notably worse than the left. He suffers from blurry vision and struggles with night driving. After discussing options: updating glasses or cataract surgery with an intraocular lens implant, he decided on surgery. Risks were discussed and reviewed.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08981",
"image_path": "slo_fundus_08981.jpg",
"filename": "data_08981.npz",
"report": "The clinical note does not provide any key details or mention the presence of glaucoma. It summarizes the process of patient care, including preparation, treatment, and review.",
"age": 41.21,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "management; minor surgery; treatment limited by social determinants or health). i spent a total of greater than (DATE_TIME preparing for, caring for (face-to-face and non face-to-face), formulating (including review of the presentation with the resident or fellow or of medical tests) and finalizing the visit for this patient.]",
"gpt4_summary": "The clinical note does not provide any key details or mention the presence of glaucoma. It summarizes the process of patient care, including preparation, treatment, and review.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08985",
"image_path": "slo_fundus_08985.jpg",
"filename": "data_08985.npz",
"report": "Patient has advanced pigmentary glaucoma. Intraocular pressure 26mm hg, corneal thickness 515/505 microns. Despite low pressure, vision loss occurred in the right eye. Surgery recommended for left eye, patient agreed for a trabeculectomy.",
"age": 61.55,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "1. pigmentary glaucoma ou vs poag ou: advanced stage ou. intraocular pressure (iop) max 26 mm hg, ou; central corneal thickness 515/505 microns. iop goal is low teens. has been on timolol since DATE_TIME. glaucoma procedures: od: PERSON alt 90 degrees od. os: none target =12 ou not possible to assess for progression od ; PERSON likely stable since DATE_TIME ? plan: visual field left eye is worse he's lost va in od from glaucoma over DATE_TIME despite low intraocular pressure v advanced disease subjectively vision is worsening surgery may be his best chance at preserving vision in os -- high myope to risk of hypotony and LOCATION is higher, discussed this with him; no blood thinners he would like to try trabeculectomy i discussed the risks/benefits/alternative of trabeculectomy surgery including but not limited to the following: infection, bleeding, droopy lid, double vision, need for additional/repeat procedure if scarring develops, lack of desired iop lowering, need for additional iop lowering medications, prolonged inflammation, possible retinal detachment and rare loss of vision. after this discussion, the patient elected to proceed. PERSON ou qhs continue cosopt 2% ou bid cont alphagan 0.2% ou bid or tid rhopressa at DATE_TIME addendum: every effort made to schedule surgery within DATE_TIME, surgery scheduled but patient declined surgery at this time i spoke to him during the visit that he may continue to lose vision should he defer surgery, he understands",
"gpt4_summary": "Patient has advanced pigmentary glaucoma. Intraocular pressure 26mm hg, corneal thickness 515/505 microns. Despite low pressure, vision loss occurred in the right eye. Surgery recommended for left eye, patient agreed for a trabeculectomy.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08991",
"image_path": "slo_fundus_08991.jpg",
"filename": "data_08991.npz",
"report": "Female patient with a history of strabismic amblyopia, esotropia, exotropia and adult strabismus surgery. She has myopia with astigmatism. Low suspicion of glaucoma, though risks include myopia. No glaucoma detected.",
"age": 41.73,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "PERSON is a DATE_TIME. female patient is a web designer Strabismic amblyopia OS she complains of eye turn os had esotropia as a child, surgery at 1-2 had patching during childhood now has exotropia os only - when tired/sick, noticing threshold is lowered has never had prism in the glasses denies diplopia h/o adult strabismus surgery 'DATE_TIME per pt myopia w/ astigmatism ou optional rx given per pt -- 'i would like to get new frames since my current ones are on their last legs' warned of rd sx's rtc for new floaters, flashes, or curtains low suspicion glaucoma suspect risks include: myopia IOP WNL OU, tcorr 0 od -1 os oct rnfl slightly thin superior od normal os. GCL normal ou. HVF WNLOU mild scarring in temporal conjunctiva os noted by PERSON in DATE_TIME for dfe, ar/refract",
"gpt4_summary": "Female patient with a history of strabismic amblyopia, esotropia, exotropia and adult strabismus surgery. She has myopia with astigmatism. Low suspicion of glaucoma, though risks include myopia. No glaucoma detected.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08992",
"image_path": "slo_fundus_08992.jpg",
"filename": "data_08992.npz",
"report": "The patient showed signs of atypical optic neuritis, indicative of a severe vision loss and long optic nerve enhancement. Tests didn't meet criteria for MS or suggest MOG/NMO. Further testing is needed.",
"age": 42.58,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "showed long segment enhancement of the optic nerve, raising the suspicion for an 'atypical' as opposed to 'idiopathic' optic neuritis. i do not have access to the initial ophthalmic exam (outside), but asked the patient to provide me with this assessment. McDonald were not met to suggest ms and both mog and nmo were negative. i will obtain a repeated mri brain and orbits which the patient was supposed to have done DATE_TIME after his initial presentation, send the mog and nmo antibodies given the imperfect sensitivity, add a fta, ace and a ct chest to rule out sarcoidosis. i will see him again in DATE_TIME, before if needed. impression: 1. right optic neuritis -episode in DATE_TIME; residual mild afferent visual dysfunction. -'atypical' given the reported severity of vision loss and long segment enhancement of the optic nerve. -nmo/mog negative at presentation 2. presbyopia ou recommendations: 1. mri brain/orbits c+c- 2. repeat mog and nmo; add ace and ct chest 3. follow up with neurology. 4. provide reports from ophthalmology. it is a pleasure to participate in the care of this patient. please do not hesitate to call with questions. ? sincerely, PERSON, PERSON spent DATE_TIME with this patient, more than 50% of which was face to face with the patient.",
"gpt4_summary": "The patient showed signs of atypical optic neuritis, indicative of a severe vision loss and long optic nerve enhancement. Tests didn't meet criteria for MS or suggest MOG/NMO. Further testing is needed.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08993",
"image_path": "slo_fundus_08993.jpg",
"filename": "data_08993.npz",
"report": "The patient visited the clinic for glaucoma. Their visual acuity was measured as 20/20 for both eyes while intraocular pressure was 14 in both eyes. No allergies found. Current medications include fluticasone propionate and spironolactone. Some tests were ordered.",
"age": 35.5,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "PERSON date of birth: DATE_TIME patient PERSON: NUMBER Institution LOCATION dept phone #: PHONE_NUMBER dept fax #: PHONE_NUMBER DATE_TIME office visit mrn: NUMBER provider: PERSON, LOCATION: Institution glaucoma main campus patient demographics address phone e-mail address LOCATION PHONE_NUMBER (home) PHONE_NUMBER (mobile) *preferred* EMAIL_ADDRESS information date of birth sex race ethnicity preferred language preferred written language DATE_TIME female white or NRP no NRP NRP reason for visit glaucoma vital signs/measurements smoking status never smoker your visual acuity as measured during DATE_TIME's visit (snellen - linear) right left dist cc 20/20 20/20 correction: glasses your intraocular pressure measured during DATE_TIME's visit (DATE_TIME) right left pressure 14 14 no eyeglass prescription found allergies as of DATE_TIME cephalexin medications and orders your current medications fluticasone propionate ( PERSON) (taking) by nasal route. spironolactone (aldactone) 100 mg tablet (taking) take 100 mg by mouth DATE_TIME. your orders normal orders this visit humphrey visual field - ou - both eyes oct, optic nerve - ou - both eyes - cirrus future labs/procedures complete by expires humphrey visual field - ou - both eyes as directed DATE_TIME, optic nerve - ou - both eyes - cirrus; optic disc; onh cube; 6mm length; no as directed DATE_TIME condition list as of DATE_TIME irritable bowel syndrome depressive disorder results summary immunizations administered on date of encounter - DATE_TIME none",
"gpt4_summary": "The patient visited the clinic for glaucoma. Their visual acuity was measured as 20/20 for both eyes while intraocular pressure was 14 in both eyes. No allergies found. Current medications include fluticasone propionate and spironolactone. Some tests were ordered.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_08994",
"image_path": "slo_fundus_08994.jpg",
"filename": "data_08994.npz",
"report": "Patient has hyperopia and was prescribed glasses. Noted narrow angles OU and enlarged c/d OU with familial history of potentially elevated IOP. IOP is within normal limits. Noted superior thinning OU; glaucoma suspected due to thinning inferiorly OS. Referred for glaucoma testing and evaluation. ERM OS observed along with possible macular hole. BCVA 20/20. Follow-up in 4-6 months.\n",
"age": 70.92,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "DATE_TIME seen in person DATE_TIME; with virtual visit DATE_TIME \u00ff 1. hyperopia - gave rx for glasses again DATE_TIME (no change) \u00ff 2. narrow angles ou s/PERSON \u00ff 3. enlarged c/d ou - father with ? elevated iop, never took drops - healthy appearing rims - iop wnl-- 12/12 prev 13 ou; prev tmax 14 - cct 557, 556- iop about measured - rnfl oct: superior thinning ou on three sets of testing, DATE_TIME through DATE_TIME, with offset peaks as likely explanation; stable DATE_TIME - gca DATE_TIME ok od, revealing PERSON (see below) - hvf ou reliable with no scattered defects DATE_TIME; DATE_TIME reliable and full od and unreliable with inferior rim defect os (pt states that she had difficulty focusing on second eye and so suspect not real change.) - disc photos DATE_TIME: c/d 0.4 od, 0.5 os, sharp without hemes, vessels normal, surrounding retinal tissues flat - discussed with glaucoma, concerned about thinning inferiorly os which is thinner on tracing than right. - refer to glaucoma for repeat testing and evaluation \u00ff 4. erm os , now with appearance of macular hole on oct associated with ganglion cell analysis for rnfl oct. - bcva 20/20 -monitored by dr. PERSON, last DATE_TIME, seeing DATE_TIME \u00ff followup 4-6 m with glaucoma for repeat testing, then me after that; with retina as planned ------------------------------------------ PERSON, md comprehensive ophthalmology LOCATION",
"gpt4_summary": "Patient has hyperopia and was prescribed glasses. Noted narrow angles OU and enlarged c/d OU with familial history of potentially elevated IOP. IOP is within normal limits. Noted superior thinning OU; glaucoma suspected due to thinning inferiorly OS. Referred for glaucoma testing and evaluation. ERM OS observed along with possible macular hole. BCVA 20/20. Follow-up in 4-6 months.\n",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08996",
"image_path": "slo_fundus_08996.jpg",
"filename": "data_08996.npz",
"report": "60 y.o. female patient has open angle glaucoma, possible angle recession, mild to moderate, in right eye; borderline ocular hypertension in the left. Also has recurrent corneal erosion and cataracts.",
"age": 61.03,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "first seen by dr. PERSON on DATE_TIME (previously followed by dr. PERSON) glaucoma medication intolerances: none target iop: DATE_TIME, tmax: 25 / 24 central corneal thickness: 578 / 578 gonioscopy: d40f 1+ ou with recession inferior od retinal nerve fiber layer, right eye: superior/inferior thinning retinal nerve fiber layer, left eye: no thinning visual fields, right eye: possible early superior nasal step, high fixation losses visual fields, left eye: watch for inferior arcuate family history: none steroids: none trauma: poked in od by son DATE_TIME asthma/copd: none other medical history and problems: none assessment/plan: 60 y.o. female in research compliance at children's # open angle glaucoma, possible angle recession, mild to moderate, right eye; borderline ocular hypertension, left eye - dr. PERSON offered treatment in past, but decided to observe - oct od has been progressing, disc photos slightly worse, vf developing possible early superior nasal step od - previously discussed start PERSON, patient started ou due to concern about asymmetric cosmesis - iop borderline od, acceptable os - continue latanoprost qhs ou - return in DATE_TIME for iop check # recurrent corneal erosion, right eye, by history - monitor # cataract, both eyes - mild, not visually significant, monitor PERSON, md",
"gpt4_summary": "60 y.o. female patient has open angle glaucoma, possible angle recession, mild to moderate, in right eye; borderline ocular hypertension in the left. Also has recurrent corneal erosion and cataracts.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_08998",
"image_path": "slo_fundus_08998.jpg",
"filename": "data_08998.npz",
"report": "The patient has pigment dispersion syndrome in the right eye and advanced primary open angle glaucoma in the left eye. The left eye also has an intra-ocular pressure of 42, which requires urgent surgery. The patient is resistant to the surgery suggestion, preferring to use marijuana.",
"age": 57.76,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "first seen by PERSON PERSON on DATE_TIME diagnosis: pigment dispersion syndrome right eye, advanced primary open angle glaucoma left eye referred by PERSON, PERSON iop: / , tmax: ( ) / ( ) tmax 42 left eye DATE_TIME central corneal thickness: / gonioscopy: scleral spur both eyes refractive error: od . . / os . . optic nerve findings on initial visit right eye: 0.8 optic nerve findings on initial visit left eye: ntc visual fields on initial visit right eye: visual fields on initial visit left eye: medication history and intolerances at first visit: combigan bid left eye, latanoprost qhs left eye, dorzolamide bid left eye . ineffective on latanoprost and LOCATION. glaucoma procedures right eye: glaucoma procedures left eye: other eye procedures right eye: other eye procedures left eye: other eye problems right eye: cataract other eye problems left eye: cataract family history: not sure, possible retina issues steroids: topical steroids trauma: none asthma: none other medical history and problems: dental issues, does not have a pcp. denies anticoagulants, dm plan: severe pigment dispersion left eye, suspect right eye intraocular pressure too high i recommended a trabeculectomy to be done urgently DATE_TIME or DATE_TIME. he prefers to try smoking a lot of marijuana as he believes this worked in the past. i explained that there is no evidence this will work and urged him to consider surgery. i also agreed to see him DATE_TIME if he refuses surgery DATE_TIME. initial note: 57 yo male with glaucoma suspect right eye, severe glaucoma left eye with intraocular pressure 42 left eye and ntc on 4 gtts left eye, needs urgent surgery.",
"gpt4_summary": "The patient has pigment dispersion syndrome in the right eye and advanced primary open angle glaucoma in the left eye. The left eye also has an intra-ocular pressure of 42, which requires urgent surgery. The patient is resistant to the surgery suggestion, preferring to use marijuana.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09007",
"image_path": "slo_fundus_09007.jpg",
"filename": "data_09007.npz",
"report": "The clinical note discusses a male patient with multiple health issues such as diabetes, hypertension, hyperlipidemia, Hepatitis C, and prostate and hepatocellular carcinoma. He is a former smoker and a potential glaucoma suspect; his mother had glaucoma. Other eye conditions include mild cataracts and cobblestone degeneration, but no retinopathy or ocular involvement from Graves' disease was found. He also has a history of eye trauma.\n",
"age": 65.11,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "DATE_TIME man former smoker w/ dm, htn, hyperlipidemia, hep c, DATE_TIME diagnosis of prostate cancer, DATE_TIME diagnosis of hepatocellular carcinoma s/p extended right hepatectomy presents for comprehensive exam. previously followed at ocb, wishes to transfer care to Institution here for testing only # cataracts ou: mild, not visually significant. observe - on flomax \u00ff # glaucoma suspect ou: tmax 20/20. mother with glaucoma iop DATE_TIME: 11/18 per ocb note - cct DATE_TIME - hvf DATE_TIME. full od. PERSON, new, unreliable DATE_TIME od full os nonspecific nasal defects, unreliable due to high fp - oct DATE_TIME: intact rnfl contours ou; ou unchanged vs DATE_TIME DATE_TIME: no thinning ou \u00ff- photo doen DATE_TIME > repeat DATE_TIME # cobblestone degeneration ou and NRP scar os scar os ? h/o blunt trauma- hit in eye with drinking glass DATE_TIME \u00ff # diabetes mellitus last a1c was 7.1 (DATE_TIME) improved from 9.3 (DATE_TIME) treating with metformin 1000 mg bid, and glimepiride, jardiance - no retinopathy - recommend bs control # graves' disease s/p rai therapy (dr. PERSON, PERSON, DATE_TIME) tsh high DATE_TIME 21.20, increased dose of levothyroxine to 175 mcg/day no history of ocular involvement \u00ff # refractive error, presbyopia new rx provided for backup, pt still happy with current glasses fu DATE_TIME, mrx, dilate, hvf/ oct",
"gpt4_summary": "The clinical note discusses a male patient with multiple health issues such as diabetes, hypertension, hyperlipidemia, Hepatitis C, and prostate and hepatocellular carcinoma. He is a former smoker and a potential glaucoma suspect; his mother had glaucoma. Other eye conditions include mild cataracts and cobblestone degeneration, but no retinopathy or ocular involvement from Graves' disease was found. He also has a history of eye trauma.\n",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09009",
"image_path": "slo_fundus_09009.jpg",
"filename": "data_09009.npz",
"report": "Patient, a former shipyard inspector, has elevated intraocular pressure in both eyes indicating the presence of glaucoma. Changes to medication regimen have been made and follow-up appointments recommended.",
"age": 88.39,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "drs. PERSON and mallery. patient is a former shipyard inspector. attending's plan: -goal intraocular pressure less than or equal to 10 mmhg, right eye. -goal intraocular pressure less than or equal to 13 mmhg, left eye. -iop above goal od and above goal os on DATE_TIME on timolol qhs ou, dorzolamide bid od, and brimonidine bid ou. -start pf cosopt bid ou. -start PERSON bid ou. -start zioptan qhs ou. -stop dorzolamide bid od. -stop brimonidine bid ou. -stop timolol bid ou. -instructions written/typed/printed out for patient (see table/details under patient instructions). -emphasized adherence to medication regimen. -preservative-free artificial tears as needed. -retinal detachment precautions were reviewed with the patient. -follow-up with dr. PERSON for general eye care. -follow-up with dr. PERSON for neuro-ophthalmology care. -follow-up with dr. PERSON for refractive care. -follow-up with dr. PERSON for dry eye care. -follow-up with dr. PERSON for retina care. -rtc in DATE_TIME at lw with iop check and disc photos ou, sooner prn. consider bgi in the future if iop remains elevated. the information above was documented by Person as a scribe for PERSON on DATE_TIME. i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "Patient, a former shipyard inspector, has elevated intraocular pressure in both eyes indicating the presence of glaucoma. Changes to medication regimen have been made and follow-up appointments recommended.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09010",
"image_path": "slo_fundus_09010.jpg",
"filename": "data_09010.npz",
"report": "The patient's tests show borderline superior thinning and decreased signal in right eye. Conditions improved by a later date. Eye pressure is stable. Provides unclear information about glaucoma.",
"age": 75.85,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "not reliable due to low signal. oct DATE_TIME: od borderline superior thinning, stable (better signal/image than 7/16). PERSON. DATE_TIME: decreased signal od with superior thinning appears worse, but associated with significant missing data superiorly. os superior thinning resolved (new at 12/15 exam) oct DATE_TIME: od superior thinning. os superior thinning (new). decr'd signal od>os oct DATE_TIME: od insufficient signal (blink). os full. DATE_TIME: wnl ou oct DATE_TIME: wnl ou, stable hrt DATE_TIME: PERSON ou dp DATE_TIME: 0.65 ou, sl hazy view with cataract ou - xalatan ou qhs resumed DATE_TIME (was on latanoprost os only from DATE_TIME to 1/08 with dr. PERSON, stopped as findings had resolved) DATE_TIME: poor signal strength oct, likely due to cataract. hvf with slight progression od. iop stable low teens. - DATE_TIME: will hold on xalatan qhs ou now s/p ce ou. >> DATE_TIME: oct and hvf stable, iop good. will follow, he feels comforted by following hvf DATE_TIME >> DATE_TIME: increase in thinning superiorly od, non-specific hvf changes >> will check again in DATE_TIME, holding xalatan ou qhs since ce \u00ff\u00ff 5. dermatochalasis ou \u00ff\u00ff 6. pvd ou: rd precautions \u00ff\u00ff 7. trace PERSONME: stable erm just nasal to LOCATION, no cme >> oct on f/u \u00ff\u00ff 8. small intraretinal hemorrhage temporal periphery os DATE_TIME, resolved DATE_TIME \u00ff\u00ff 9. drusen temporal to macula ou",
"gpt4_summary": "The patient's tests show borderline superior thinning and decreased signal in right eye. Conditions improved by a later date. Eye pressure is stable. Provides unclear information about glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09013",
"image_path": "slo_fundus_09013.jpg",
"filename": "data_09013.npz",
"report": "The patient has been prescribed latanoprost (xalatan) 0.005% ophthalmic solution for nightly use, which suggests the presence of glaucoma.",
"age": 74.62,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "divorced",
"note": "PERSON telephone: PHONE_NUMBER fax: PHONE_NUMBER hours: e-prescribed (1 of 1) latanoprost (xalatan) 0.005 % ophthalmic solution sig: place 1 drop into each eye nightly. start: DATE_TIME quantity: 2.5 ml refills: 12 your orders normal orders this visit humphrey visual field - ou - both eyes oct, optic nerve - ou - both eyes - optic disc photos - ou - both eyes results summary immunizations administered on date of encounter - DATE_TIME none patient gateway activation information your account is ready to use. LOCATION.",
"gpt4_summary": "The patient has been prescribed latanoprost (xalatan) 0.005% ophthalmic solution for nightly use, which suggests the presence of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09015",
"image_path": "slo_fundus_09015.jpg",
"filename": "data_09015.npz",
"report": "Patient underwent selective laser trabeculoplasty in right eye and will return to glaucoma clinic for intraocular pressure check. Possible further surgery if pressure remains high. Presence of glaucoma indicated.",
"age": 61.76,
"gender": "female",
"race": "white",
"ethnicity": "unknown",
"language": "other",
"maritalstatus": "married or partnered",
"note": "surgery. selective laser trabeculoplasty right eye DATE_TIME return to glaucoma clinic DATE_TIME intraocular pressure check possible surgical planning if intraocular pressure still high",
"gpt4_summary": "Patient underwent selective laser trabeculoplasty in right eye and will return to glaucoma clinic for intraocular pressure check. Possible further surgery if pressure remains high. Presence of glaucoma indicated.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09022",
"image_path": "slo_fundus_09022.jpg",
"filename": "data_09022.npz",
"report": "Patient has complex photopsias, possibly due to migraine aura given her history. No additional neurological issues or imaging findings. Normal afferent function and no optic/chorioretinal inflammation. Reviewed retinal detachment warning signs. Plan for follow-up. No glaucoma mentioned.",
"age": 39.6,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "of persistent, more complex photopsias in DATE_TIME may be more reflective of a migraine aura (particularly in light of her prior history of the same and persistent symptoms with eye closure), the duration of her more recent symptoms would be unusual for a migrainous process. the absence of additional neurological involvement or reported findings on imaging would also argue against occipital seizures, while her normal afferent function and static clinical course reduces suspicion for an optic nerve or chorioretinal inflammatory disorder. we accordingly reviewed warning signs for retinal detachment as well as continued routine ophthalmological care unless she notices changes in her symptoms. i will plan to see ms. papas in follow-up as needed, although she understood to contact me with any questions or concerns. thank you for the opportunity to participate in ms. PERSON's care. sincerely, PERSON, LOCATION were spent during this encounter and in reviewing the medical record, exclusive of procedures.",
"gpt4_summary": "Patient has complex photopsias, possibly due to migraine aura given her history. No additional neurological issues or imaging findings. Normal afferent function and no optic/chorioretinal inflammation. Reviewed retinal detachment warning signs. Plan for follow-up. No glaucoma mentioned.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09024",
"image_path": "slo_fundus_09024.jpg",
"filename": "data_09024.npz",
"report": "The female patient has thyroid disease, dryness, and a refractive error managed with OTC readers. She is suspected of having glaucoma due to eye asymmetry. No proptosis or discharge present. Possible allergies.",
"age": 65.01,
"gender": "female",
"race": "white",
"ethnicity": "hispanic",
"language": "spanish",
"maritalstatus": "married or partnered",
"note": "DATE_TIME. female DATE_TIME/o thyroid disease mild ul retraction, no proptosis at prn dryness 2. refractive error: cpm with otc readers 3. glaucoma susp b/o c:d asymmetry od>os fhx maternal aunt PERSON cct 598,596 thick ou, so actual iop is lower than measured hvf full ou oct wnl ou plan: observe closely 4. bilateral conjunctival injection ou no discharge ou ? allergic vs due to des or thyroid disease no relief with refresh bid - tid try to add zaditor ou bid (high pollen count right now) f/u 6 PERSON, iop, hvf, LOCATION, oct and dp PERSON scribing for dr. Person i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "The female patient has thyroid disease, dryness, and a refractive error managed with OTC readers. She is suspected of having glaucoma due to eye asymmetry. No proptosis or discharge present. Possible allergies.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09026",
"image_path": "slo_fundus_09026.jpg",
"filename": "data_09026.npz",
"report": "The clinical note does not provide specific information on the presence of glaucoma. It only mentions a review of ocular imaging by a resident.",
"age": 64.4,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "unknown",
"note": "with the resident and review of medical tests, including two sets of reviews of ocular imaging) and finalizing the note.]",
"gpt4_summary": "The clinical note does not provide specific information on the presence of glaucoma. It only mentions a review of ocular imaging by a resident.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09028",
"image_path": "slo_fundus_09028.jpg",
"filename": "data_09028.npz",
"report": "Patient has a history of sequential non-arteritic anterior ischemic optic neuropathy (NAION). Optic disc swelling resolved with prednisone treatment. Acuity measured 20/200 in right eye, a decrease from a prior level of 20/30. OCT suggests no structural change to right nerve but shows optic atrophy in left eye. Patient is overall stable but needs reading glasses. No presence of glaucoma noted.",
"age": 50.8,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "and central deep depression. high fl. os: nasal quadrant depression and superior temporal inner-arcuate region depression (stable compared to DATE_TIME) oct, optic nerve - ou - both eyes - cirrus; optic disc; rnfl, gcc right eye reliability was good. left eye reliability was good. notes od: prnfl thinning superiorly and inferiorly (stable compared to DATE_TIME, avg 54 microns). diffuse gcipl thinning (avg 54 microns) os: PERSON thinning diffusely, greatest superiorly and inferiorly (avg 51 microns). gcipl thinning sparing a sector LOCATION to the fovea along the horizontal (avg 56 microns). formulation: ms. PERSON has a history of sequential naion, and given the severe vision loss already present in the right eye, we treated with prednisone. her optic disc swelling resolved and she was tapered off of prednisone. her exam DATE_TIME is overall stable, although her acuity measured 20/200 od today and was 20/30 at the last visit DATE_TIME. notably the acuity od has ranged to a poor as cf at the first visits with us in DATE_TIME and DATE_TIME, and then was noted to be better probably due to finding a preserved island of vision within her scotoma at subsequent visits. she does not notice a functional change between the eyes though notes that she now needs reading glasses. oct suggests there has been no structural change to the right nerve. oct was only done in the edematous stable os, so we now see optic atrophy os with a preserved sector of gcipl superior-nasal to the foveal. overall i think she is stable. i will see her back again in DATE_TIME to recheck her exam. impression: 1. naion os, probable naion od recommendations: 1. follow up in DATE_TIME ? ? PERSON, LOCATION note: greater than half of this DATE_TIME visit was spent counseling the patient on the medical condition or coordinating care.",
"gpt4_summary": "Patient has a history of sequential non-arteritic anterior ischemic optic neuropathy (NAION). Optic disc swelling resolved with prednisone treatment. Acuity measured 20/200 in right eye, a decrease from a prior level of 20/30. OCT suggests no structural change to right nerve but shows optic atrophy in left eye. Patient is overall stable but needs reading glasses. No presence of glaucoma noted.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09029",
"image_path": "slo_fundus_09029.jpg",
"filename": "data_09029.npz",
"report": "The clinical note indicates the patient is on medication for both eyes, taken once nightly. Alternatives include latanoprost, xalatan, travatan z, travaprost, and tafluprost. The patient is advised to consult the glaucoma department for routine queries.",
"age": 59.26,
"gender": "male",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "medication route frequency LOCATION (teal) both eyes 1x/night \u00f8 some medications that may be prescribed in lieu of this medication include: latanoprost, xalatan, travatan z, travaprost, LOCATION, LOCATION, LOCATION/tafluprost (preservative-free). always wait DATE_TIME (by the clock) in between eye drops. please bring this to your next visit. for routine questions, please call PHONE_NUMBER (LOCATION, ask for glaucoma department) or PHONE_NUMBER (longwood). for emergencies, please call PHONE_NUMBER and ask for the glaucoma physician on-call.",
"gpt4_summary": "The clinical note indicates the patient is on medication for both eyes, taken once nightly. Alternatives include latanoprost, xalatan, travatan z, travaprost, and tafluprost. The patient is advised to consult the glaucoma department for routine queries.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09032",
"image_path": "slo_fundus_09032.jpg",
"filename": "data_09032.npz",
"report": "The patient has a diagnosis of primary open angle glaucoma in both eyes with thin corneas (508/480) and elevated intraocular pressure (23/24). The patient has no medication intolerances and will start treatment with latanoprost.",
"age": 53.23,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "first seen by PERSON PERSON on DATE_TIME diagnosis: primary open angle glaucoma, PERSON both eyes referred by optometrist PERSON. PERSON target iop: / , tmax: ( ) / ( ) 23 central corneal thickness: 508 / 481 corneal hysteresis: 8.7/7.8 gonioscopy: open to scleral spur both eyes, 3+ pigment refractive error: od . . / os . . optic nerve findings on initial visit right eye: mild inferior and superior thinning optic nerve findings on initial visit left eye: inferior>superior thinning, c/d 0.9 visual fields on initial visit right eye: superior nasal step visual fields on initial visit left eye: superior arcuate medication history and intolerances at first visit: none glaucoma procedures right eye: glaucoma procedures left eye: other eye procedures right eye: PERSON other eye procedures left eye: PERSON other eye problems right eye: other eye problems left eye: family history: maternal cousin steroids: none trauma: does boxing, sometimes gets punched in the eye asthma: none other medical history and problems: migraines, sleep apnea, hld initial note: moderate oag os>od, PERSON - thin corneas (508/480), elevated intraocular pressure (23/24), young patient, also with risk factors for ntg (migraine, sleep apnea) - iop goal <14 ou - start treatment with latanoprost vs slt vs both plan: recommend selective laser trabeculoplasty or latanoprost and he will start with latanoprost but come on an selective laser DATE_TIME for treatment. PERSON scribing for dr. PERSON (DATE_TIME, 10:17 am) i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "The patient has a diagnosis of primary open angle glaucoma in both eyes with thin corneas (508/480) and elevated intraocular pressure (23/24). The patient has no medication intolerances and will start treatment with latanoprost.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09037",
"image_path": "slo_fundus_09037.jpg",
"filename": "data_09037.npz",
"report": "Patient started Rhopressa for both eyes. If ineffective, may need laser surgery or Xen. Glaucoma not explicitly mentioned. Has insignificant cataract in both eyes.",
"age": 63.59,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "unknown",
"note": "- start rhopressa once nightly both eyes - if intraocular pressure remains elevated after adding rhopressa, could repeat selective laser trabeculoplasty or do xen - return to clinic DATE_TIME for intraocular pressure check and repeat baseline testing # cataract, both eyes - not visually significant, monitor i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow. i have reviewed the resident/fellow's notes and made any necessary changes.",
"gpt4_summary": "Patient started Rhopressa for both eyes. If ineffective, may need laser surgery or Xen. Glaucoma not explicitly mentioned. Has insignificant cataract in both eyes.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09039",
"image_path": "slo_fundus_09039.jpg",
"filename": "data_09039.npz",
"report": "30 y.o. with high myopia, trace posterior subcapsular cataracts, and visual disturbance in the left eye, causing darker vision. Uses old contact in left eye; non-smoker and no diabetes. No mention of glaucoma.",
"age": 30.87,
"gender": "female",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "30 y.o. high myopia ou > updated glasses rx given rgp wearer - using old contact in os, has appt to see cl clinic DATE_TIME trace posterior subcapsular cataracts ou os> od - nonsmoker, no diabetes, no steroids > observe PERSON gland dysfunction > warm compresses, lid hygiene, artificial tears > flax seed / fish oil supplementation visual disturbance - vision in the left eye appears 'darker' than the right eye - color vision PERSON shows - rnfl oct show thinning but difficult to interpret because of tilted nerves - mac oct wnl > unclear etiology. likely not an optic nerve issue. could be the slightly worse psc causing this symptom. no other alarming features. will observe, repeat testing in DATE_TIME, repeat hvf/ rnfl oct",
"gpt4_summary": "30 y.o. with high myopia, trace posterior subcapsular cataracts, and visual disturbance in the left eye, causing darker vision. Uses old contact in left eye; non-smoker and no diabetes. No mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09046",
"image_path": "slo_fundus_09046.jpg",
"filename": "data_09046.npz",
"report": "Patient is taking Combigan (timolol and brimonidine) 2x/day for glaucoma. Timed dosage, emergency contacts provided.",
"age": 72.97,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "(dark blue) both eyes 2x/day ** this medication is also known as combigan, and it represents a combination of timolol and brimonidine. always wait DATE_TIME (by the clock) in between eye drops. please bring this to your next visit. for routine questions, please call PHONE_NUMBER (LOCATION) or PHONE_NUMBER (LOCATION). for emergencies, please call PHONE_NUMBER and ask for the glaucoma physician on-call",
"gpt4_summary": "Patient is taking Combigan (timolol and brimonidine) 2x/day for glaucoma. Timed dosage, emergency contacts provided.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09047",
"image_path": "slo_fundus_09047.jpg",
"filename": "data_09047.npz",
"report": "56-year-old male podiatrist with hypertension, hypothyroidism referred by doctor. Possibility of glaucoma suspected due to cup:disc asymmetry os>od. Patient exhibits fluctuating inferior defects and thin superior borderline inferior. Patient desires consultation with glaucoma specialist.",
"age": 56.45,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "56 y.o. male podiatrist with hypertension, hypothyroidism works DATE_TIME (DATE_TIME) on DATE_TIME referred by dr. PERSON suspect based on cup:disc asymmetry os>od fam hx: none tmax: 17/17 cct: 546/532 gonio DATE_TIME (dr. PERSON): ou open to cbb hvf DATE_TIME: od ?early inferior nasal step, os ?early inferior arcuate DATE_TIME: PERSON, os persistent ?early inferior arcuate DATE_TIME: od full, os inferior defect DATE_TIME: od nonspecific nasal defects, os borderline reliable (8/14 fl) full DATE_TIME: od full, os persistent inferior defects (fluctuates each visit) rnfl DATE_TIME: PERSON, os thin superior borderline inferior DATE_TIME: PERSON, os thin superior borderline inferior (stable from DATE_TIME) disc photos: DATE_TIME last dilated: DATE_TIME seen by PERSON rao DATE_TIME for abnormal oct os: may be segmentation artifact due to slight tilt of nerve. hvf DATE_TIME with possible persistent inferior defect (though fluctuates) which matches superior thinning on oct. >> findings discussed at length with patient again. he would like to see glaucoma specialist (dr. PERSON has left) to discuss pros/cons of LOCATION/o viral conjunctivitis in DATE_TIME (treated with LOCATION for DATE_TIME in march), with subepithelial infiltrates ou (os was near visual axis); resolved >> cont preservative-free artificial tears as needed - blepharitis/meibomian gland dysfunction ou azasite was too expensive >> continue warm compresses (encouraged regular use), artificial tears prn - refractive error >> a prescription for new glasses was given to the patient DATE_TIME for bifocals for computer and reading (computer glasses alone didn't work due to inability to read paperwork when working with patients) f/up with me in DATE_TIME, no dilation, sooner prn",
"gpt4_summary": "56-year-old male podiatrist with hypertension, hypothyroidism referred by doctor. Possibility of glaucoma suspected due to cup:disc asymmetry os>od. Patient exhibits fluctuating inferior defects and thin superior borderline inferior. Patient desires consultation with glaucoma specialist.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09050",
"image_path": "slo_fundus_09050.jpg",
"filename": "data_09050.npz",
"report": "The note mentions a goal of maintaining intraocular pressure in both eyes. The patient is advised to continue with cosopt, pf medication, and wear protective glasses. No explicit mention of glaucoma.",
"age": 52.72,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "eyes -preservative-free artificial tears as needed. DATE_TIME/o failed dsek x2, right eye -follow-up with dr. PERSON for cornea care. 5. social/systemic issues: referred by dr. PERSON. previously seen by PERSON PERSON. attending's plan: -goal intraocular pressure less than or equal to *** mmhg, right eye. -goal intraocular pressure less than or equal to *** mmhg, left eye. -iop *** goal od and *** goal os on DATE_TIME on cosopt bid od and pf bid od. -continue cosopt bid od. -continue pf bid od. -instructions written/typed/printed out for patient (see table/details under patient instructions). -emphasized adherence to medication regimen. -preservative-free artificial tears as needed. -monocular precautions discussed: patient should wear polycarbonate glasses at all times to protect seeing eye. -follow-up with dr. PERSON for cornea care. -rtc in *** with iop check, dilation, and disc photos ou, sooner prn. i personally spent DATE_TIME preparing for, caring for the patient (face-to-face and non face-to-face), and finalizing the visit for this patient. the information above was documented by Person as a scribe for PERSON on DATE_TIME. i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "The note mentions a goal of maintaining intraocular pressure in both eyes. The patient is advised to continue with cosopt, pf medication, and wear protective glasses. No explicit mention of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09056",
"image_path": "slo_fundus_09056.jpg",
"filename": "data_09056.npz",
"report": "The patient is using three kinds of eye drops for glaucoma: Brimonidine (Alphagan) in left eye twice a day, Cosopt (Dorzolamide/Timolol) in both eyes twice a day, and Latanoprost (Xalatan) in left eye.",
"age": 83.69,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "thank you for allowing us to participate in your care. please follow up as instructed. if you have any problems, such as decreasing vision, increasing pain, or increasing redness, please call at anytime. if you are having an emergency, we have a DATE_TIME emergency room at 243 LOCATION in LOCATION. PERSON 8am-5pm: PHONE_NUMBER for emergencies or DATE_TIME: PHONE_NUMBER and ask for glaucoma doctor on call please use your eyedrops as follows: drug eye top color schedule brimonidine (alphagan) left eye purple 2x/day cosopt (dorzolamide/timolol) both eyes blue 2x/day latanoprost (xalatan) left eye teal DATE_TIME allow DATE_TIME between drops. - it is very important to take your eye drops DATE_TIME as instructed, including DATE_TIME of your next visit. - please remember to bring your eye drops to your next visit. - if you run out of any of your drops before your next visit, please have the pharmacy call your doctor to authorize a refill.",
"gpt4_summary": "The patient is using three kinds of eye drops for glaucoma: Brimonidine (Alphagan) in left eye twice a day, Cosopt (Dorzolamide/Timolol) in both eyes twice a day, and Latanoprost (Xalatan) in left eye.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09060",
"image_path": "slo_fundus_09060.jpg",
"filename": "data_09060.npz",
"report": "Patient has 2+ posterior capsule opacity. YAG capsulotomy OD is being considered if CME is controlled. It's also suggested to perform trabeculotomy 360 OS if IOP rises. No clear mention of glaucoma.",
"age": 61.54,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "2+ pco. i explained that we can consider yag capsulotomy od in the near future if dr. PERSON agrees that it would be beneficial and if cme is controlled. we can sign consents over telemedicine if dr. PERSON agrees to yag capsulotomy od. -rtc in DATE_TIME for iop check and oct rnfl/gcc ou, sooner prn. in the future, i will likely perform trabeculotomy 360 os if iop above goal. if va not 20/20 od, consider yag capsulotomy od in future if cme resolved and with dr. PERSON's blessing. the information above was documented by Person as a scribe for PERSON on DATE_TIME. i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "Patient has 2+ posterior capsule opacity. YAG capsulotomy OD is being considered if CME is controlled. It's also suggested to perform trabeculotomy 360 OS if IOP rises. No clear mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09063",
"image_path": "slo_fundus_09063.jpg",
"filename": "data_09063.npz",
"report": "The patient has early manifest glaucoma in the right eye and is a glaucoma suspect with increased cup/disc ratio in the left eye. Regular monitoring and treatment with latanoprost are advised.",
"age": 68.26,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "DATE_TIME f \u00ff # likely early manifest glaucoma, right eye # glaucoma suspect with increased cup/disc ratio, left eye [ fhx: no [ cct: 565,568 [ oct DATE_TIME: inferior thinning od, nonspecific os [ hvf DATE_TIME: low reliability with sup > inf defect od, full os - given concordant findings in the right eye, likely early glaucoma in the right eye. - reviewed importance of treatment and f/u in the prevention of progressive permanent vision loss from glaucoma. - iop acceptable on latanoprost. continue PERSON. - handout previously given for selective laser trabeculoplasty as well. # cataract, both eyes, minimal and not visually significant. - monitor for now. \u00ff rtc DATE_TIME, sooner prn previously: # hx of retinal hemorrhage in peripheral retina, seen previously. no retinal hemorrhages seen DATE_TIME. - monitor for recurrence \u00ff # s/p excision of rll lesions (DATE_TIME PERSON), doing well \u00ff # refractive error, needs glasses for hyperopia and presbyopia. - rx given for new glasses for DATE_TIME driving; may continue otc readers. \u00ff",
"gpt4_summary": "The patient has early manifest glaucoma in the right eye and is a glaucoma suspect with increased cup/disc ratio in the left eye. Regular monitoring and treatment with latanoprost are advised.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09073",
"image_path": "slo_fundus_09073.jpg",
"filename": "data_09073.npz",
"report": "Patient with stable idiopathic intracranial hypertension and possible polycystic ovary syndrome has been advised to gradually discontinue diamox. No mention of glaucoma.",
"age": 25.73,
"gender": "female",
"race": "white",
"ethnicity": "hispanic",
"language": "english",
"maritalstatus": "single",
"note": "been stable. considering the stability of her weight and her afferent exam and the uncertainty as to whether her new headaches were caused by pseudotumor cerebri or a potential viral infection, it is reasonable to attempt a taper of diamox. prior to her visit to the ed, she had not taken diamox since DATE_TIME and was asymptomatic until DATE_TIME. as such, i recommended decreasing the dose by half, then discontinuation, which she understands is a trial to determine if she needs to take this medicine. impression: 1. h/o idiopathic intracranial hypertension with optic nerve head pallor and stably depressed visual fields 2. possible polycystic ovary syndrome recommendations: 1. zyrtec 5 mg (can be increased to 10 mg DATE_TIME if not helpful). if the daily headaches continue, consider 500 mg bid of diamox 2. follow up with obgyn for possible treatment of suspected polycystic ovary syndrome 3. follow up with neuro-ophthalmology clinic in DATE_TIME. decrease diamox 500 mg to qd for DATE_TIME, then stop 2. follow up in DATE_TIME this note was prepared with the assistance of PERSON, md, neuro-ophthalmology fellow.",
"gpt4_summary": "Patient with stable idiopathic intracranial hypertension and possible polycystic ovary syndrome has been advised to gradually discontinue diamox. No mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09074",
"image_path": "slo_fundus_09074.jpg",
"filename": "data_09074.npz",
"report": "Pt has large suspicious nevus in left macula and small nevus in right eye, with no significant changes observed. History of GI stromal tumor in remission. Non-glaucomatous visual field loss in left eye linked to optic nerve. No evidence of glaucoma.",
"age": 69.9,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "1. large suspicious nevus in left macula. pt actively followed by PERSON gragadous DATE_TIME for this lesion. fundus photos of this lesion suggest no meaningful change since DATE_TIME. \u00ff 2. small nevus od. \u00ff 3. h/o gist ( gi stromal tumor) in remission. followed at tufts. don't think this is related to eye issues. \u00ff 4. nonglaucomatous visual field loss os that is optic nerve based. there is a mild dychromatopsia os but missing some color plates seems to be related to his inferior arcuate scotoma which may be retinal based. no pathological cupping is seen and optic nerves have not changed vs DATE_TIME photos that in our chart. tmax 15 mm hg \u00ff 5. h/o skin cas due to lots of sunbathing. PERSON. pt claims has been stable. pt followed by a dermatologist \u00ff plan: visual field stable both eyes rnfl oct stable visual field changes are due to macular lesion left eye which is mostly superior to the macula explaining the inferior defect no clear evidence of glaucoma rtc 1 yr visual field , rnfl oct , dilate",
"gpt4_summary": "Pt has large suspicious nevus in left macula and small nevus in right eye, with no significant changes observed. History of GI stromal tumor in remission. Non-glaucomatous visual field loss in left eye linked to optic nerve. No evidence of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09076",
"image_path": "slo_fundus_09076.jpg",
"filename": "data_09076.npz",
"report": "45 y.o. Asian, non-Hispanic female. No diagnosis of glaucoma. Immunizations administered. Patient gateway account activated.",
"age": 45.09,
"gender": "female",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "a 45 y.o. asian, non-hispanic female with no diagnosis of glaucoma. immunizations administered on date of encounter - DATE_TIME none patient gateway activation information your account is ready to use. activate your account using following steps: 1. visit URL. 2. click 'enroll now' and create your user account. for more detailed steps on enrollment please click the 'learn more' link underneath the 'enroll now' button on URL. important information a",
"gpt4_summary": "45 y.o. Asian, non-Hispanic female. No diagnosis of glaucoma. Immunizations administered. Patient gateway account activated.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09077",
"image_path": "slo_fundus_09077.jpg",
"filename": "data_09077.npz",
"report": "The patient has severe mixed mechanism glaucoma in both eyes, exhibiting advanced diffuse thinning. On glaucoma medications, has no known intolerances. Gout, Hypothyroidism, Rheumatoid Arthritis also noted.",
"age": 74.41,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "married or partnered",
"note": "first seen by dr. PERSON on DATE_TIME (previously followed by DR PERSON ) glaucoma medication intolerances: none target iop: DATE_TIME, tmax: 35 / 24 central corneal thickness: 480 / 480 gonioscopy: c30f 2+ ou, scattered low pas ou retinal nerve fiber layer, right eye: advanced diffuse thinning retinal nerve fiber layer, left eye: advanced diffuse thinning visual fields, right eye: inferior altitudinal, superior arcuate visual fields, left eye: central island family history: grandmother steroids: none trauma: none asthma/copd: none other medical history and problems: PERSON's witness, esrd on hemodialysis, rheumatoid arthritis, htn, hld, hypothyroidism, gout, history of breast cancer assessment/plan: 74 y.o. NRP-speaking female # mixed mechanism glaucoma, severe, both eyes - s/p phaco/trabeculectomy ou (od DATE_TIME dr. PERSON, os DATE_TIME dr. PERSON), s/p selective laser NRP DATE_TIME - had gap in visits and off drops most of DATE_TIME, significant oct progression since DATE_TIME; long gap again DATE_TIME-DATE_TIME in setting of DATE_TIME - follow vf with 24-2 od and 10-2 os - iop acceptable ou, vf and oct roughly stable ou - continue latanoprost qhs ou, dorzolamide/timolol bid ou, brimonidine bid ou - return in DATE_TIME for iop check # s/p cataract surgery with posterior chamber intraocular lens, both eyes - doing well, monitor PERSON, md",
"gpt4_summary": "The patient has severe mixed mechanism glaucoma in both eyes, exhibiting advanced diffuse thinning. On glaucoma medications, has no known intolerances. Gout, Hypothyroidism, Rheumatoid Arthritis also noted.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09078",
"image_path": "slo_fundus_09078.jpg",
"filename": "data_09078.npz",
"report": "The patient has nuclear sclerosis and cupping in both eyes, suspicious for glaucoma. However, thick cct is unusual. Normal OCT and HVF, no increased IOP.",
"age": 72.12,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "imp: nuclear sclerosis ou cupping ou, susp for glaucoma, but anomalous with thick cct; nl oct and nl hvf; no iop elevation refr error lid margin lesion od: patient reports no growth for DATE_TIME. monitor. blepharitis history ant corneal dystrophy sup os>od \u00ff plan: rx=m glasses prn warm compr/art tears rtc DATE_TIME--repeat hvf and oct then",
"gpt4_summary": "The patient has nuclear sclerosis and cupping in both eyes, suspicious for glaucoma. However, thick cct is unusual. Normal OCT and HVF, no increased IOP.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09080",
"image_path": "slo_fundus_09080.jpg",
"filename": "data_09080.npz",
"report": "Patient suspected of glaucoma due to family history and specific test findings, including cup-disc asymmetry and borderline IOP. Also has astigmatism, presbyopia.",
"age": 45.72,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "impression and plan: 1) glaucoma suspect -based on family history (father). cup to disc asymmetry -iop borderline (21 ou) -vf with non specific defects although more pronounced nasally URLllow. 2) astigmatism and presbyopia ou -updated glasses prescription given to patient follow up DATE_TIME with vf 24-2, oct on, pachymetry ou PERSON, md",
"gpt4_summary": "Patient suspected of glaucoma due to family history and specific test findings, including cup-disc asymmetry and borderline IOP. Also has astigmatism, presbyopia.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09081",
"image_path": "slo_fundus_09081.jpg",
"filename": "data_09081.npz",
"report": "55-year-old female presented with ocular surface irritation and is a glaucoma suspect due to increased cup/disc ratio and asymmetry in her left eye. Patient has mild dry eye disease, environmental allergies, and a conjunctival lesion.",
"age": 55.13,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "55 f for f/u from PERSON ed DATE_TIME with ocular surface irritation. also for glaucoma suspect. # dry eye disease, both eyes, mild. associated with NRP gland dysfunction. improved with treatment. - continue artificial tears ou qid prn. - start artificial tear ointment ou qhs. - discussed controlling environmental factors, including avoiding/blocking air movement around the face. - discussed taking frequent breaks while reading, using the computer or phone, or watching tv. - continue warm compresses. - handout given to patient. # glaucoma suspect with increased cup/disc ratio and cup/disc asymmetry, left > right eye [ fhx: maternal grandaunt [ cct: 435,451 [ oct gcc DATE_TIME: full ou [ oct rnfl DATE_TIME: full od, borderline thinning PERSON os [ hvf DATE_TIME: generalized depression od, full os - no intervention required at this time. continue to monitor. # DATE_TIME allergic conjunctivitis, both eyes. - antihistamine eyedrops as needed. # conjunctival lesion, right eye, possible concretion rtc DATE_TIME, sooner prn",
"gpt4_summary": "55-year-old female presented with ocular surface irritation and is a glaucoma suspect due to increased cup/disc ratio and asymmetry in her left eye. Patient has mild dry eye disease, environmental allergies, and a conjunctival lesion.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09084",
"image_path": "slo_fundus_09084.jpg",
"filename": "data_09084.npz",
"report": "The patient has severe primary open angle glaucoma in the right eye, moderate in the left. Patient is continuing medications latanoprost and cosopt. Recommended selective laser trabeculoplasty in left eye, with patient understood risks and wishes to proceed. Also has history of shingles with no ocular involvement, mild eretinal membrane, and diabetes without eye complications.",
"age": 76.44,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "?# severe primary open angle glaucoma od > os (moderate) - pachymetry (DATE_TIME); tmax 26/22; no fhx of glaucoma - hvf with PERSON (60/71) with sup and PERSONp slt od DATE_TIME (falkenstein) - tg = low to mid teens ou; borderline DATE_TIME with likely oct progression os ? - continue latanoprost qhs ou - continue cosopt bid ou - recommend slt os - risks, benefits, alternatives of selective laser trabeculoplasty os explained in detail to patient, including but not limited to bleeding, pain, decreased vision, corneal edema, inflammation, increased intraocular pressure, persistent inflammation, or a complication requiring need for another procedure. informed consent obtained. patient expresses understanding and wishes to proceed. - previously discussed filtration surgery with dr. PERSON # pciol ou with pco od > os - to undergo yag cap od by dr. PERSON # h/o l v1 shingles without ocular involvement - follow # mild erm ou with ?angioid streaks ou - follow # dm2 - no npdr or csme on most recent dfe with dr. PERSON and bs control - follow ? social/systemic: dm2 ? plan for slt os as above",
"gpt4_summary": "The patient has severe primary open angle glaucoma in the right eye, moderate in the left. Patient is continuing medications latanoprost and cosopt. Recommended selective laser trabeculoplasty in left eye, with patient understood risks and wishes to proceed. Also has history of shingles with no ocular involvement, mild eretinal membrane, and diabetes without eye complications.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09086",
"image_path": "slo_fundus_09086.jpg",
"filename": "data_09086.npz",
"report": "43-year-old female, glaucoma suspect, underwent glaucoma screening. Tests showed normal OCT and HVF results in both eyes but non-specific defects noted. Family history of glaucoma present.",
"age": 43.71,
"gender": "female",
"race": "white",
"ethnicity": "hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "43 y.o.female h/o glaucoma suspect, presents for glaucoma screening tests 1. glaucoma suspect ou -iop 16/16 -c/d 0.5/0.6 -(+) family history -oct and hvf on DATE_TIME normal oct: right eye reliability was good. left eye reliability was good. findings right eye normal left eye normal. hvf: hvf mean deviation (os) - left eye +0.38 hvf mean deviation (od) - right eye +0.20 right eye reliability/fixation was poor mean deviation was calculated to be: -+0.2 db. interpretation of the testing revealed: non-specific defects. left eye reliability/fixation was poor. mean deviation was calculated to be: +0.38 db. interpretation of the testing revealed: non-specific defects advised pt to have a complete eye examination, including dilation, on a DATE_TIME basis.",
"gpt4_summary": "43-year-old female, glaucoma suspect, underwent glaucoma screening. Tests showed normal OCT and HVF results in both eyes but non-specific defects noted. Family history of glaucoma present.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09089",
"image_path": "slo_fundus_09089.jpg",
"filename": "data_09089.npz",
"report": "The clinical note does not provide information about the presence of glaucoma. The patient is instructed to return if their symptoms worsen or vision drops.",
"age": 18.69,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "and oct gcc analysis 3. return sooner if any drop in vision or worsening of symptoms this note was prepared with the assistance of PERSON, LOCATION pgy3 attending: i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow. i have reviewed the resident/fellow's notes and made any necessary changes.",
"gpt4_summary": "The clinical note does not provide information about the presence of glaucoma. The patient is instructed to return if their symptoms worsen or vision drops.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09091",
"image_path": "slo_fundus_09091.jpg",
"filename": "data_09091.npz",
"report": "The patient has a high risk of glaucoma in both eyes. No immunizations were administered at the time of the visit. A new patient gateway account is ready for activation.",
"age": 63.78,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "and high glaucoma risk in both eyes results summary immunizations administered on date of encounter - DATE_TIME none patient gateway activation information your account is ready to use. activate your account using following steps: 1. visit URL. 2. click 'enroll now' and create your user account. important information about your account: \u0007 if you already have a account, please sign in with your existing username and your account will automatically be activated in our new portal - \u0007 you must log into your account within DATE_TIME or activation code will expire. \u0007 trouble logging in? use support link found on the top right side of the login page. \u0007 need help? support team makes every effort to respond to phone or email messages within DATE_TIME. to reach the support team, email EMAIL_ADDRESSPHONE_NUMBER. calls or messages are answered DATE_TIME, DATE_TIME, est - and will make every effort to contact you withi.",
"gpt4_summary": "The patient has a high risk of glaucoma in both eyes. No immunizations were administered at the time of the visit. A new patient gateway account is ready for activation.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09093",
"image_path": "slo_fundus_09093.jpg",
"filename": "data_09093.npz",
"report": "Patient has moderate stage primary open-angle glaucoma (POAG) in both eyes (OU). Intraocular pressure improving but fluctuates. Cataracts in both eyes observed. Dr. recommended selective laser trabeculoplasty (SLT) to stabilize eye pressure.",
"age": 72.2,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "per dr. PERSON DATE_TIME: 1. poag ou, moderate stage. - iop better DATE_TIME into low teens (but likely fluctuates) - 547/560 cct, t max 24/22 - hvf fluctuates but appears to be progressing od>os - discussed slt od first to stabilize her iop at a lower level, r/b of the procedure discussed in details, she voiced understanding and wants to proceed. informed consent signed, will schedule na for the procedure. long discussion was done about nature of the disease, visual prgnosis and management options, she voiced understanding, all questions were answered. \u00ff - d/c brimonidine bid ou - continue PERSON ou \u00ff 2. cataract ou -per dr. PERSON. des ou -artificial tears \u00ff 4. subconjuctival heme od - vision stable, no eye pain, no signs of infection or intraocular heme - observe imp: brimonidine allergy with blepharoconjunctivitis ou poag ou cataract ou refr error plan: stop brimonidine cont xalatan rx=m f/u w dr. PERSON",
"gpt4_summary": "Patient has moderate stage primary open-angle glaucoma (POAG) in both eyes (OU). Intraocular pressure improving but fluctuates. Cataracts in both eyes observed. Dr. recommended selective laser trabeculoplasty (SLT) to stabilize eye pressure.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09095",
"image_path": "slo_fundus_09095.jpg",
"filename": "data_09095.npz",
"report": "The patient was referred for glaucoma management. They have primary open angle glaucoma, a history of noncompliance with Azopt, and previously underwent neck surgery and cataract surgery. Other conditions include asthma and an allergy to a medication, now tolerated.",
"age": 79.82,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "referred by PERSONfor management of glaucoma had neck surgery (fell downstairs, long hospitalization); pt is at stoneham office usually \u00ff 1. poag ou (= primary open angle glaucoma) - s/p slt #1 os DATE_TIME - tmax DATE_TIME ou, admits to poor compliance x DATE_TIME when going thru cancer treatments, - fhx negative - cct 519,517 (thin ou) - hvf full od, + progression of sa and ia defects noted os-->? secondary to wosening cataract vs progression - note h/o PERSON allergy but taking now without problems; h/o asthma, on advair and inhalers, could not tolerate timolol, but pt barely remembers the specifics of this; says he's on new breathings meds and would be willing to try this in the future if needed; - h/o noncompliance on azopt 2. s/p cataract surgery ou - s/p phaco od DATE_TIME (wants driver's license so wanted phaco od); 1 PERSON, azopt, brimonidine, timolol x 1 after pod#1 iop check - s/p phaco/iol/istent os DATE_TIME, significant posterior pressure from coughing - had steroid response post ce os now resolved \u00ff 3. erm os (= epiretinal membrane, left eye) - affecting bcva -->considering erm peel with PERSON plan: prev patient of PERSON ; seen nz DATE_TIME visual field is worse but rnfl oct stable has not had visual field in DATE_TIME and intraocular pressure was high in the interim , now much better cont xalatan qhs ou; PERSON bid ou; PERSON bid both eyes refraction given mild posterior capsular opacification rtc 4 mths for visual field sita fast and dilation",
"gpt4_summary": "The patient was referred for glaucoma management. They have primary open angle glaucoma, a history of noncompliance with Azopt, and previously underwent neck surgery and cataract surgery. Other conditions include asthma and an allergy to a medication, now tolerated.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09096",
"image_path": "slo_fundus_09096.jpg",
"filename": "data_09096.npz",
"report": "67yof, glaucoma suspect, has narrow angles requiring laser and follows with ocb for glaucoma. Was seen at joslin, recommended for laser procedure. Seeking second opinion.",
"age": 67.96,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "67yof presents for evaluation. new patient to dr. PERSON DATE_TIME pmh of lung cancer on chemo, cns avm s/p craniotomy follows with PERSON PERSON at ocb as glaucoma suspect. went to joslin recently and was told that she needs laser for narrow angles. 1. glaucoma suspect -follows with ocb for glaucoma suspect with no intervention, however was seen at joslin on DATE_TIME and recommended for unknown laser procedure for glaucoma. here for second opinion. -enlarged c:d ou -tmax 16/15 -iop DATE_TIME 12/13 -hvf DATE_TIME: left superior homonymous LOCATION, longstanding per patient after craniotomy for avm -oct rnfl DATE_TIME: inferior losses ou (per last ocb note, has been stable for years) 2. narrow angle ou -here for second opinion, recommended ?lpi at LOCATION. sister had lpi recently -gonio today with narrow angles temporally and superiorly ou rec: - defer dilation - lpi od 3. corneal verticillata -prior amiodarone use, not currently. not visually signficant 4. left superior homonymous quadrantanopia -seen on hvf DATE_TIME -long standing after craniotomy for avm in DATE_TIME. epiretinal membrane ou -monitor 6. refractive error -mrx provided",
"gpt4_summary": "67yof, glaucoma suspect, has narrow angles requiring laser and follows with ocb for glaucoma. Was seen at joslin, recommended for laser procedure. Seeking second opinion.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09102",
"image_path": "slo_fundus_09102.jpg",
"filename": "data_09102.npz",
"report": "63-year-old patient with hypertension, hypercholesterolemia, type 2 diabetes mellitus, and prostate cancer. Has optic disc cupping indicating glaucoma suspicion, but no definite glaucoma signs. Started on latanoprost.",
"age": 63.95,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "63 y.o. new patient with hypertension, hypercholesterolemia, type 2 dm, prostate ca here for eye exam. wishes to transfer care here type 2 diabetes mellitus with no diabetic retinopathy ou hemoglobin a1c date value ref range status DATE_TIME 7.1 (h) 4.3 - 6.4 % final > importance of blood pressure, blood sugar and lipid control emphasized > DATE_TIME exams glaucoma suspect based on optic disc cupping - tcurrent: 19/20 - tmax: patient does not know - gonioscopy: - central corneal thickness: DATE_TIME: DATE_TIME 84/77 od wnl os borderline thin superiorly - hvf: DATE_TIME od full os unreliable with isolated defects inferiorly - family history: sister has glaucoma - race: aa > followed by dr. PERSON in LOCATION, started on latanoprost >? testing shows no definite signs of glaucoma. he was reportedly started on latanoprost for high iop. continue latanoprost for now. retrieve old records > iop check in DATE_TIME refractive error > updated glasses prescription given DATE_TIME, iop check, gonio, disc photos",
"gpt4_summary": "63-year-old patient with hypertension, hypercholesterolemia, type 2 diabetes mellitus, and prostate cancer. Has optic disc cupping indicating glaucoma suspicion, but no definite glaucoma signs. Started on latanoprost.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09103",
"image_path": "slo_fundus_09103.jpg",
"filename": "data_09103.npz",
"report": "Patient has thyroid eye disease, Graves' disease, and compressive optic neuropathy. Experiencing vision issues, but no glaucoma indicated. Potential treatments include steroids, radiation, Tepezza or strabismus surgery.",
"age": 71.47,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "oral prednisolone in DATE_TIME. he has not had orbital decompression. he was prescribed separate prism glasses for distance and near by his optometrist DATE_TIME. with these glasses, he reports he no longer sees diplopia, but is still experiencing some visual 'confusion'. his central visual acuities were 20/20-2 od and 20/30-2 os, without improvement with pinhole. ishihara testing revealed 7/8 od and full colors os. he exhibited mild limitation of abduction in both eyes. alternate cover testing revealed comitant right hypertropia and esotropia. he continues to have epiphora, lid erythema and edema, and conjunctival injection. PERSON can continue with his habitual glasses and should return to dr. PERSON for continued management of his thyroid eye disease and compressive optic neuropathy and dr. PERSON's recommendations on whether additional treatment with steroids, radiation, or Tepezza would be beneficial. strabismus surgery can be considered as an option in the future, after the patient is no longer in the active phase of ted. impression: 1. thyroid eye disease with compressive optic neuropathy; active phase 2. oblique binocular diplopia 2/2 #1 3. graves' disease 4. PERSON, lid erythema and edema, and conjunctival erythema 2/2 #1 plan: 1. follow-up with dr. PERSON for management of ted/compressive optic neuropathy; discuss further treatment with steroids, radiation, or candidacy for Tepezza 2. can pursue strabismus surgery in the future; follow-up prn dean PERSON, PERSON neuro-ophthalmology LOCATION PHONE_NUMBER",
"gpt4_summary": "Patient has thyroid eye disease, Graves' disease, and compressive optic neuropathy. Experiencing vision issues, but no glaucoma indicated. Potential treatments include steroids, radiation, Tepezza or strabismus surgery.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09105",
"image_path": "slo_fundus_09105.jpg",
"filename": "data_09105.npz",
"report": "The patient, a female, has primary open angle glaucoma with likely progression and advanced cupping of the optic nerve. Also, has cataracts in both eyes which are not visually significant.",
"age": 39.47,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "other",
"maritalstatus": "unknown",
"note": "PERSON is a DATE_TIME. female 1. primary open angle glaucoma -tmax 22 by history -cct thick ou -humphrey visual field (hvf) 5/16 sup alt od, inf arc/sup paracentral os--progression likely compared with DATE_TIME -optic nerve with adv cupping ou -no asthma (had at birth, not anymore , never had an asthma attack ) 2. cataract both eyes -not visually significant plan -diagnosis and treatment options dicussed w pt in detail and all questions answered -brimonidine tid ou, PERSON ou -add travatan ou -f/u 2 PERSON check",
"gpt4_summary": "The patient, a female, has primary open angle glaucoma with likely progression and advanced cupping of the optic nerve. Also, has cataracts in both eyes which are not visually significant.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09107",
"image_path": "slo_fundus_09107.jpg",
"filename": "data_09107.npz",
"report": "The note is an appointment confirmation at a Neuro-Ophthalmology suite. There's no indication of glaucoma. Pupils might be dilated for the exam, causing temporary blurred vision and light sensitivity.",
"age": 41.67,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "married or partnered",
"note": "DATE_TIME PERSON 20 PERSON 02302 dear ms. PERSON: we thank you for choosing Institution for your care and we look forward to welcoming you for your appointment on DATE_TIME at DATE_TIME with dr. PERSON. our neuro-ophthalmology suite is located on the 9th floor of the Institution. we ask patients to allow DATE_TIME for a first appointment. if you have any questions or concerns, please contact our office at PHONE_NUMBER. please be aware that your pupils might need to be dilated for your exam. dilation of your pupils will produce blurred vision for at least 2-3 hours, and it will make your eyes sensitive to light. these effects can make it difficult, or unsafe, to drive a car. as such, it is advisable to attend your appointment with someone who can drive, or at least you should be prepared to remain in the area until you believe your vision has returned to normal. * reminder: if you have had a previous mri of your brain or orbits, please mail out your disc to neuro-ophthalmology. sincerely, naomi francisque administration assistant",
"gpt4_summary": "The note is an appointment confirmation at a Neuro-Ophthalmology suite. There's no indication of glaucoma. Pupils might be dilated for the exam, causing temporary blurred vision and light sensitivity.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09108",
"image_path": "slo_fundus_09108.jpg",
"filename": "data_09108.npz",
"report": "The patient has stable vision but can be refracted to 20/50 in the left eye. They have undergone selective laser trabeculoplasty for better intraocular pressure control - an indicator for glaucoma management.",
"age": 72.81,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "looks ess stable refracted for glasses DATE_TIME to optimize vision, able to be refracted to 20/50 left eye subjectively he feels his vision is about the same *selective laser trabeculoplasty for more intraocular pressure control os continue brimonidine bid os continue cosopt bid os last dilated exam: DATE_TIME with retina DATE_TIME rnfl: DATE_TIME last visual field: DATE_TIME os only baseline disc photos: DATE_TIME return to glaucoma clinic for selective laser trabeculoplasty left eye in LOCATION consents signed in clinic DATE_TIME PERSON acting as scribe for dr. PERSON on DATE_TIME at DATE_TIME.",
"gpt4_summary": "The patient has stable vision but can be refracted to 20/50 in the left eye. They have undergone selective laser trabeculoplasty for better intraocular pressure control - an indicator for glaucoma management.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09111",
"image_path": "slo_fundus_09111.jpg",
"filename": "data_09111.npz",
"report": "The patient is a 59-year-old male with a status of preglaucoma. Both eyes healthy with no detectable thinning or visual field loss. No treatment needed currently, reassessment suggested.",
"age": 59.65,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "first seen by dr. PERSON on DATE_TIME glaucoma medication intolerances: none target iop: DATE_TIME, tmax: 18 / 18 central corneal thickness: 544 / 543 gonioscopy: d40f 1+ ou retinal nerve fiber layer, right eye: no thinning retinal nerve fiber layer, left eye: no thinning visual fields, right eye: full visual fields, left eye: full family history: none steroids: none trauma: none asthma/copd: possible emphysema other medical history and problems: dm2, htn, hld, bipolar disorder, LOCATION, s/p defibrillator, htn, hld, osa assessment/plan: 59 y.o. male # glaucoma suspect, both eyes - reports that dr. PERSON told him that he has preglaucoma - iop acceptable ou - nerves healthy on exam, vf and oct normal DATE_TIME - continue to monitor without initiating treatment - recommend DATE_TIME exam with local optometrist or comprehensive ophthalmologist - happy to have patient return to see me at any time as needed # cataract, both eyes - mild, not visually significant, monitor PERSON scribing for dr. PERSON i attest that i was present while this encounter was recorded and agree that the information entered by my scribe and updated by me is complete and accurate. PERSON, md",
"gpt4_summary": "The patient is a 59-year-old male with a status of preglaucoma. Both eyes healthy with no detectable thinning or visual field loss. No treatment needed currently, reassessment suggested.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09112",
"image_path": "slo_fundus_09112.jpg",
"filename": "data_09112.npz",
"report": "Patient has a history of flap tear os and retinal detachment precautions, for which they were given urgent return instructions. No explicit mention of glaucoma.",
"age": 61.45,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "shadows. - rtc urgently for any of the above signs # history of flap tear os - s/p laser - follow-up with PERSON as scheduled - retinal detachment precautions were reviewed with the patient in detail and they are to return immediately for symptoms including increase in and/or change in floaters, worsening flashing lights, and curtains or shadows. rtc 8-12 oct rnfl, hvf 24-2, dilation ou, refraction ou PERSON, md",
"gpt4_summary": "Patient has a history of flap tear os and retinal detachment precautions, for which they were given urgent return instructions. No explicit mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09119",
"image_path": "slo_fundus_09119.jpg",
"filename": "data_09119.npz",
"report": "The patient is taking Ergocalciferol (Vitamin D2) 2,000 unit tablets, but no other medications reported. They have been referred to ophthalmology and specifically named tests suggest a concern for potential glaucoma. The patient's conditions include pulmonary lymphangioleiomyomatosis and obstructive sleep apnea syndrome.",
"age": 44.35,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "PERSON; frequency: bid; directions: not available; details: dispense: ml(s); date: DATE_TIME erin PERSON DATE_TIME patient not taking PERSON DATE_TIME 9:02 am received from: partners lmr ergocalciferol, vitamin d2, 2,000 unit tab take 3 tablets by mouth DATE_TIME. vitamin d2 (ergocalciferol) 2000 unit tablet; dose: 50000 units; form: take 25 tablet; route: PERSON; frequency: not available; directions: not available; details: dispense: tablet(s); taking; status: active; source: LOCATION,PERSON; date: DATE_TIME your orders normal orders this visit ambulatory referral to Institution ophthalmology humphrey visual field - ou - both eyes oct, optic nerve - ou - both eyes - optic disc photos - ou - both eyes condition list as of DATE_TIME pulmonary lymphangioleiomyomatosis obstructive sleep apnea syndrome results summary immunizations administered on date of encounter - DATE_TIME none",
"gpt4_summary": "The patient is taking Ergocalciferol (Vitamin D2) 2,000 unit tablets, but no other medications reported. They have been referred to ophthalmology and specifically named tests suggest a concern for potential glaucoma. The patient's conditions include pulmonary lymphangioleiomyomatosis and obstructive sleep apnea syndrome.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09120",
"image_path": "slo_fundus_09120.jpg",
"filename": "data_09120.npz",
"report": "Patient has partial superior temporal and superior nasal deficiencies, normal iris, and tilted disc with inf ppa. No mention of glaucoma.",
"age": 71.97,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "pupils dark light right PERSON 3 2 left LOCATION 3 2 visual fields left right restrictions partial superior temporal, superior nasal deficiencies partial superior temporal, superior nasal deficiencies extraocular movement right left result ortho ortho -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- pain with upgaze ou neuro/psych oriented x3: yes mood/affect: normal dilation both eyes: 5.0%/0.5% phenylephrine/tropicamide @ DATE_TIME slit lamp and fundus exam external exam right left external normal normal (skin protoburtance near cheek left) slit lamp exam right left lids/lashes blepharitis, dermatochalasis. rul papilloma laterally blepharitis, dermatochalasis conjunctiva/sclera normal normal cornea no guttae; no ks no guttae; no ks anterior chamber normal normal iris no pxf; no tid no pxf; no tid lens 2+ nuclear sclerosis 2+ nuclear sclerosis vitreous normal normal fundus exam right left disc tilted with ppa; inf temporal sloping tilted with ppa; with inf temporal sloping; large heme superior to disc c/d ratio 0.7 0.7 macula normal normal vessels normal normal periphery confluent cobblestone temporally confluent cobblestone temporally refraction wearing rx sphere cylinder axis add right +1.25 -0.50 045 +2.75 left LOCATION -0.50 170 +2.75",
"gpt4_summary": "Patient has partial superior temporal and superior nasal deficiencies, normal iris, and tilted disc with inf ppa. No mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09122",
"image_path": "slo_fundus_09122.jpg",
"filename": "data_09122.npz",
"report": "The patient previously diagnosed with glaucoma is myopic and has trouble with eye drops due to burning. Has tried different options with no success. Reports iris color lightening but no signs of it in the exam. Underwent selective laser treatment on left eye. The right eye is stable while the left eye may be worse. Currently monitoring as the risk of further surgery is high due to slowly progressing disease and cardiomyopathy. They're to return to the clinic in 5 months.",
"age": 67.74,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "# second opinion glaucoma prev seen with PERSON ; dx in DATE_TIME cl wearer ; -5 myopoe having trouble with drops PERSON:adopted / steroids: qvar for asthma/ trauma: none prior surgery: none med intolerance: has tried brim, LOCATION, ltn, timolol, LOCATION, timolol occudose -- had burning with all ; discontinued all drops rhopressa ttarget: / , tmax: ( ) / ( ) 16 ou here off all drops (17 per records) cct: 540 / 540 gonioscopy: cbb, concave config rnfl oct sup/inf defect od, sup defect PERSON defect os>od -- od confirmed worse DATE_TIME patient reports iris color lightening over DATE_TIME ? pds -- no def signs of it on my exam DATE_TIME however , though gonio config is suggestive htn; parathyroid surgery s/p selective laser NRPME s/p selective laser trabeculoplasty left eye DATE_TIME plan: s/p kdb right eye intraocular pressure hasnt changed much right eye is stable left eye visual field and rnfl oct may be a little worse discussed with patient monitor for now since risk of trabeculectomy is likely higher than her very slowly progressive disease she also has cardiomyopathy recommend check bp at DATE_TIME return to clinic 5 mths visual field left eye",
"gpt4_summary": "The patient previously diagnosed with glaucoma is myopic and has trouble with eye drops due to burning. Has tried different options with no success. Reports iris color lightening but no signs of it in the exam. Underwent selective laser treatment on left eye. The right eye is stable while the left eye may be worse. Currently monitoring as the risk of further surgery is high due to slowly progressing disease and cardiomyopathy. They're to return to the clinic in 5 months.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09127",
"image_path": "slo_fundus_09127.jpg",
"filename": "data_09127.npz",
"report": "The clinical note does not provide specific details about the patient's condition. There's no mention of glaucoma or any other specific diagnosis.",
"age": 79.71,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "examination, and he also discussed his findings, conclusions and management strategy with the patient'}. any part of this letter that was prepared by the resident or fellow was reviewed and modified as necessary by dr. PERSON to complete the finalized summary.) ? note: greater than half of this {encounter time:19197::'25','40','45','60'} minute visit was spent counseling the patient on the medical condition or coordinating care.",
"gpt4_summary": "The clinical note does not provide specific details about the patient's condition. There's no mention of glaucoma or any other specific diagnosis.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09131",
"image_path": "slo_fundus_09131.jpg",
"filename": "data_09131.npz",
"report": "The patient has a macular pucker in the left eye, post two surgeries, and immature cataracts in both eyes. No mention of glaucoma is present.",
"age": 69.07,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "of fusion 4. macular pucker, os, status post surgery x2 (DATE_TIME) 5. immature cataract, ou recommendations: 1. obtain an updated refraction for progressive glasses and return DATE_TIME after to reassess prisms 2. return to clinic DATE_TIME after obtaining progressive glasses 3. follow up with general ophthalmology as scheduled this note was written with assistance from PERSON, neuro-ophthalmology fellow. PERSON, PERSON neuro-ophthalmology LOCATION PHONE_NUMBER fax PHONE_NUMBER ----- [administrative formulation. my impression of this case is based upon an assessment of the the patient's chronic problems as detailed under 'diagnoses' above that pose a threat to vision / neurological function or systemic health. my assessment of this case also included review of the following data: 1) results of tests and outside documents (specifically: a review of prior external notes; review of unique test results (including those described under 'ancillary studies' above); ordering unique tests; assessment requiring independent historian); 2) independent interpretation of tests performed by dr. PERSON; and 3) discussion or communication or management with PERSON. with respect to management, this patient has a - moderate risk of morbidity related to (drug management; minor surgery; treatment limited by social determinants or health). i spent a total of greater than (DATE_TIME preparing for, caring for (face-to-face and non face-to-face), formulating (including review of the presentation with the resident or fellow or of medical tests) and finalizing the visit for this patient.]",
"gpt4_summary": "The patient has a macular pucker in the left eye, post two surgeries, and immature cataracts in both eyes. No mention of glaucoma is present.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09133",
"image_path": "slo_fundus_09133.jpg",
"filename": "data_09133.npz",
"report": "40 y.o. white, non-hispanic male without glaucoma diagnosis. Reviewed and updated resident/fellow's notes.",
"age": 40.94,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "a 40 y.o. white, non-hispanic male with no diagnosis of glaucoma. reviewed the resident/fellow's notes and made any necessary changes.",
"gpt4_summary": "40 y.o. white, non-hispanic male without glaucoma diagnosis. Reviewed and updated resident/fellow's notes.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09135",
"image_path": "slo_fundus_09135.jpg",
"filename": "data_09135.npz",
"report": "Suspected glaucoma with present cupping OU and family history. However, hvf and oct are normal. Lower intraocular pressure (iop). Refractive error 568 OU. Plan: yearly glasses prescription, hvf and oct.",
"age": 49.95,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "imp: cupping ou, susp for glaucoma, +fh, but normal hvf and oct again; lower iop; 568 ou refr error plan: rx=m glasses yrly w hvf and oct",
"gpt4_summary": "Suspected glaucoma with present cupping OU and family history. However, hvf and oct are normal. Lower intraocular pressure (iop). Refractive error 568 OU. Plan: yearly glasses prescription, hvf and oct.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09139",
"image_path": "slo_fundus_09139.jpg",
"filename": "data_09139.npz",
"report": "The clinical note provides no specific details about the patient's condition or the presence of glaucoma.",
"age": 74.48,
"gender": "male",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "while this encounter was recorded and agree that the information entered by my scribe and updated by me is complete and accurate.",
"gpt4_summary": "The clinical note provides no specific details about the patient's condition or the presence of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09145",
"image_path": "slo_fundus_09145.jpg",
"filename": "data_09145.npz",
"report": "The patient has post concussive syndrome, mild convergence insufficiency, light sensitivity, and seizure. No signs of glaucoma found in optic nerve HEADS exam. Suggested FL41 lenses and convergence exercises.",
"age": 42.22,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "and the patient is orthophoric in all gaze directions in the distance. at near, there is a small angle (4 pd) PERSON. his near point of convergence varied from 10 cm to 8 cm with effort. on dilated fundus evaluation, both optic nerve heads and macula have a normal appearance. i obtained an oct rnfl that shows no rnfl loss. in summary, this patient has symptoms consistent with a post concussive syndrome. his exam shows mild convergence insufficiency but he denies PERSON at near. since he still reports some light sensitivity, i suggested him to try fl41 lenses which have been shown to improve symptoms in post concussive patients. i also advised him to continue convergence exercises and use artificial tears on a regular basis. if his blurry vision persists, i would suggest to obtain a refraction with an optometrist looking more specifically for latent hyperopia. i will see him again in DATE_TIME, before if needed. ? impression: 1. post concussive syndrome -improvement since head trauma (DATE_TIME) -residual symptoms (as per notes) 2. convergence insufficiency -mild; likely secondary to #1 -no diplopia at near 3. light sensitivity -secondary to #1. 4. seizure x 1 -followed by neurology -normal mri brain and eeg 3. add ? recommendations: 1. fl41 lenses 2. at prn 3. updated refraction with optometrist - rule out latent hyperopia. 4. follow up in DATE_TIME, before if needed. it is a pleasure to participate in the care of this patient. please do not hesitate to call with questions. ? sincerely, ? PERSON, PERSON spent DATE_TIME with this patient, more than 50% of which was face to face with the patient.",
"gpt4_summary": "The patient has post concussive syndrome, mild convergence insufficiency, light sensitivity, and seizure. No signs of glaucoma found in optic nerve HEADS exam. Suggested FL41 lenses and convergence exercises.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09146",
"image_path": "slo_fundus_09146.jpg",
"filename": "data_09146.npz",
"report": "The 63-year-old patient with a history of myomectomy, knee arthroplasty, depression, has family history of glaucoma. She has early signs of glaucoma, mild cataracts, refractive error, and small choroidal nevus.",
"age": 63.85,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "63 PERSON with history of myomectomy, l knee arthroplasty DATE_TIME, depression np DATE_TIME, previously followed dr. PERSON, then dr. PERSON. fhx glaucoma, reports hvf normal with dr. PERSON in past (but thinks dif type of machine?) ta 15/16. cct 580/547 (thick/ave). PERSON (paternal gmother and aunt) 1st hvf here DATE_TIME DATE_TIME: od: superior arcuate, ?early ins. os: superior arcuate with possible rim artifact DATE_TIME DATE_TIME: od: inferior and superior thinning, borderline nasal thinning. os: inferior thinning. oct DATE_TIME: od borderline signal, is thinning. os inferior thinning. dfe w/ healthy neuroretinal rim, no evidence of focal thinning. PERSON likely limited 2/2 myopia >> will repeat hvf in DATE_TIME given losses c/w glaucomatous loss \u00ff 2. PERSON (dr. PERSON) -stable, rd precautions \u00ff 3. mild cataracts ou with small psc ou -asx, will continue to monitor \u00ff 4. refractive error - toric PERSON wearer -updated rx with dr. PERSON 5. small choroidal nevus os 6. PERSON >> likely dysfunction of blink with tear hygiene, but will attempt p/i on f/u \u00ff h nguyen pgy-4 i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow. i have reviewed the resident/fellow's notes and made any necessary changes.",
"gpt4_summary": "The 63-year-old patient with a history of myomectomy, knee arthroplasty, depression, has family history of glaucoma. She has early signs of glaucoma, mild cataracts, refractive error, and small choroidal nevus.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09147",
"image_path": "slo_fundus_09147.jpg",
"filename": "data_09147.npz",
"report": "The patient has multiple conditions like nasal obstruction, various allergies, diabetes, obesity, hyperlipidemia, asthma, hypertension, and facial swelling, among others. No mention of glaucoma.",
"age": 56.12,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "oct, optic nerve - ou - both eyes - condition list as of DATE_TIME nasal obstruction non-seasonal allergic rhinitis due to fungal spores syncope colitis, indeterminate diverticulitis PERSON syndrome gastroesophageal reflux disease diabetes mellitus obesity cyst and pseudocyst of pancreas classic ige mediated food allergy complication of procedure: spt scallop (DATE_TIME) spt oyster (DATE_TIME) spt clam (DATE_TIME) spt crab (DATE_TIME) spt lobster (DATE_TIME) hyperlipidemia asthma facial swelling hypertension chronic non-seasonal allergic rhinitis morbid obesity due to excess calories results summary immunizations administered on date of encounter - DATE_TIME none",
"gpt4_summary": "The patient has multiple conditions like nasal obstruction, various allergies, diabetes, obesity, hyperlipidemia, asthma, hypertension, and facial swelling, among others. No mention of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09149",
"image_path": "slo_fundus_09149.jpg",
"filename": "data_09149.npz",
"report": "The clinical note does not contain specific details about the presence of glaucoma. The orders placed include a Humphrey visual field test for both eyes.",
"age": 28.28,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "your orders future appointments provider department dept phone DATE_TIME PERSON, md, PERSONn LOCATION PHONE DATE_TIME DATE_TIME a sola-LOCATION, PERSON Institution PHONE DATE_TIME DATE_TIME PERSON, md, PERSONtitution oph trauma main campus PHONE_NUMBER orders placed this visit humphrey visual field - ou - both eyes results summary immunizations administered on date of encounter - DATE_TIME none patient gateway activation information your account is ready to use. activate your account using following steps:",
"gpt4_summary": "The clinical note does not contain specific details about the presence of glaucoma. The orders placed include a Humphrey visual field test for both eyes.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09156",
"image_path": "slo_fundus_09156.jpg",
"filename": "data_09156.npz",
"report": "The patient has chronic angle closure glaucoma resulting from neovascular glaucoma. IOP is too high. Plans to start Rhopressa, possibly need cpc, and continue Alphagan and other meds. Laser surgery discussed and patient agreed. Additionally, other conditions noted are advanced proliferative diabetic Retinopathy, pseudophakia which is being monitored, and ptosis.",
"age": 76.71,
"gender": "male",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "married or partnered",
"note": "fellow assessment and plan: 1. chronic angle closure glaucoma resulting from neovascular glaucoma odos oct rnfl DATE_TIME: stable oct rnfl DATE_TIME: od: stable, os maybe worse hvf DATE_TIME: od sad, PERSON hvf DATE_TIME: od sup arcuate, os inferior arcuate latanoprost qhs not effective timolol did not lower pressure suspect brimonidine adverse events instructed importance of taking medications to prevent blindness \u00ff rec: - cont cosopt bid ou - refer to glaucoma for consideration for slt \u00ff 4. posterior vitreous detachment ou retinal detachment precautions were reviewed with the patient in detail including increase in and/or change in floaters, worsening flashing lights, and curtains or shadows \u00ff 5. cataract ou not visually significant, monitor \u00ff",
"gpt4_summary": "The patient has diabetes mellitus, hypertension, glaucoma with an intraocular pressure in the 20s, posterior vitreous detachment, and cataract. Medications for glaucoma are ineffective, and a referral to glaucoma specialist is suggested.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09176",
"image_path": "slo_fundus_09176.jpg",
"filename": "data_09176.npz",
"report": "Patient was prescribed latanoprost ophthalmic solution for glaucoma treatment. The patient is instructed to place 1 drop into each eye nightly.",
"age": 59.3,
"gender": "female",
"race": "black",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "married or partnered",
"note": "cvs/pharmacy telephone: PHONE_NUMBER fax: PHONE_NUMBER hours: e-prescribed (1 of 1) latanoprost (xalatan) 0.005 % ophthalmic solution sig: place 1 drop into each eye nightly. start: DATE_TIME quantity: 2.5 ml refills: 11 your orders normal orders this visit PERSON visual field - ou - both eyes oct, optic nerve - ou - both eyes - cirrus optic disc photos - ou - both eyes results summary immunizations administered on date of encounter - DATE_TIME none patient gateway activation information your account is ready to use. activate your account using following steps:",
"gpt4_summary": "Patient was prescribed latanoprost ophthalmic solution for glaucoma treatment. The patient is instructed to place 1 drop into each eye nightly.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09180",
"image_path": "slo_fundus_09180.jpg",
"filename": "data_09180.npz",
"report": "Patient has glaucoma and treatment adherence discussed to prevent permanent vision loss. Regular follow-ups are essential. Tonometry readings indicate normal eye pressure. Other exam findings, including pupils and visual fields, are normal.",
"age": 78.25,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "review of natural history and management options discussed. importance of lifelong follow up and adherence to treatments discussed in order to lower risk of permanent vision loss/blindness from glaucoma. all questions answered. i personally spent DATE_TIME preparing for, caring for this patient's glaucoma, and finalizing the visit for this patient. below you will find my full exam findings. if you have questions, please do not hesitate to call me. i look forward to following NRP along with you. sincerely, PERSON, PERSON no recipients base eye exam visual acuity (snellen - linear) right left dist sc 20/60 +1 20/40 -1 dist ph sc PHONE_NUMBER correction: glasses tonometry (ora, DATE_TIME) right left pressure 9.9 11.7 tonometry #2 (applanation, DATE_TIME) right left pressure 8 10 gonioscopy right left temporal cbb cbb nasal cbb cbb superior cbb cbb inferior cbb cbb pupils pupils dark light PERSON right PERSON 4 3 none left LOCATION 4 3 none visual fields (counting fingers) left right full full extraocular movement right left full, ortho full, ortho neuro/psych oriented x3: yes mood/affect: normal slit lamp and fundus exam slit lamp exam right left lids/lashes normal normal conjunctiva/sclera 1+ injection 1+ injection cornea verticillata verticillata anterior chamber normal normal iris normal normal lens normal normal vitreous normal normal fundus exam right left disc thin rim thin rim c/d ratio 0.9 0.9 macula normal normal",
"gpt4_summary": "Patient has glaucoma and treatment adherence discussed to prevent permanent vision loss. Regular follow-ups are essential. Tonometry readings indicate normal eye pressure. Other exam findings, including pupils and visual fields, are normal.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09181",
"image_path": "slo_fundus_09181.jpg",
"filename": "data_09181.npz",
"report": "The patient has stable bilateral optic neuropathy. No clear cause has been identified, but there's no ongoing concern due to stability of her condition. No glaucoma present.",
"age": 67.1,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "24-2. strategy: sita - fast. reliability: poor. mean deviation: -5.17 db db. pattern standard deviation: 2.89 db db. change: stable. foveal threshold: reduced. findings: non-specific defects. oct, optic nerve - ou - both eyes - cirrus; gcc, rnfl right eye good. 78. stable. abnormal superior. diffuse thinning. left eye 69. stable. abnormal superior. diffuse thinning. impression and recommendations: in summary, ms. PERSON's examination again reveals a largely stable bilateral optic neuropathy relative to her examination with dr. PERSON in DATE_TIME. the etiology of her optic neuropathy remains somewhat unclear, particularly in the absence of abrupt vision loss suggestive of an inflammatory or ischemic process, progression compatible with an infiltrative or compressive etiology, or probable toxic exposures or nutritional deficiencies (again noting that the relatively few cases of tacrolimus-associated optic neuropathy reported in the literature have generally involved relatively rapid or severe vision loss). her prior vascular imaging and fundus examination are also not suggestive of ocular ischemic syndrome despite her episodes of transient vision loss. regardless, the stability of her examination and oct over this period provide some reassurance against an ongoing process, and so we discussed continued observation for further vision changes with routine eye examinations. i will plan to see ms. PERSON in follow-up as needed for new or worsening symptoms, although she understood to contact me with any additional questions or concerns. thank you for the opportunity to participate in ms. PERSON's care. sincerely, PERSON, LOCATION were spent during this encounter and in reviewing the medical record, exclusive of procedures.",
"gpt4_summary": "The patient has stable bilateral optic neuropathy. No clear cause has been identified, but there's no ongoing concern due to stability of her condition. No glaucoma present.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09186",
"image_path": "slo_fundus_09186.jpg",
"filename": "data_09186.npz",
"report": "NZ patient has juvenile onset normal tension glaucoma in both eyes, target IOP at mid-teens. Has cataract in both eyes, superglue injury to left eye. Medication: Brimonidine, Latanoprost.",
"age": 51.17,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "first seen by dr. PERSON on DATE_TIME, nz patient diagnosis: juvenile onset normal tension glaucoma both eyes target iop: DATE_TIME, tmax: 20 (DATE_TIME) / 18 ( ) central corneal thickness: 580 / 545 corneal hysteresis: 9.3 / 9.4 * gonioscopy: refractive error: od . . / os . . optic nerve findings on initial visit right eye: optic nerve findings on initial visit left eye: visual fields on initial visit right eye: early inferior nasal visual fields on initial visit left eye: diffuse loss medications being used at first visit: brimonidine latanoprost medication intolerances: none known glaucoma procedures right eye: glaucoma procedures left eye: other eye procedures right eye: other eye procedures left eye: other eye problems right eye: cataract other eye problems left eye: had superglue injury to left eye, cataract family history: mother as an adult steroids: no trauma: no asthma: no other medical history and problems: hyperlipidemia initial note: juvenile onset open angle glaucoma with low intraocular pressure and target around 13, central corneal thickness does have intraocular pressure in midteens at times, mostly stable dry eyes plan: # juvenile onset normal tension glaucoma, both eyes - intraocular pressure too high right eye, at target left eye, though visual field stable both eyes - add dorzolamide 2 times per day right eye - continue brimonidine twice a day both eyes, latanoprost once nightly both eyes - return to clinic DATE_TIME for intraocular pressure check, optical coherence tomography both eyes # cataract, both eyes - mild, not visually significant, monitor i, PERSON, am acting as scribe for PERSONmd, PERSON for patient PERSON on DATE_TIME.",
"gpt4_summary": "NZ patient has juvenile onset normal tension glaucoma in both eyes, target IOP at mid-teens. Has cataract in both eyes, superglue injury to left eye. Medication: Brimonidine, Latanoprost.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09187",
"image_path": "slo_fundus_09187.jpg",
"filename": "data_09187.npz",
"report": "Patient experiencing allergies and itching. Advised warm compress, lid hygiene, scrubs, and artificial tears for comfort. Precautions for retinal detachment discussed. No mention of glaucoma.",
"age": 37.7,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "allergies/itching. recommend warm compress and lid hygiene/scrubs qd to bid ou. recommend artificial tears/rewetting drops as needed for ocular comfort. retinal detachment precautions reviewed. followup in DATE_TIME for iop check. rtc sooner as needed.",
"gpt4_summary": "Patient experiencing allergies and itching. Advised warm compress, lid hygiene, scrubs, and artificial tears for comfort. Precautions for retinal detachment discussed. No mention of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09190",
"image_path": "slo_fundus_09190.jpg",
"filename": "data_09190.npz",
"report": "75 y.o. patient presents with focus issues, intermittent blurred vision. Examined for glaucoma - results reassuring. Plan: artificial tears, warm compresses, updated glasses prescription.",
"age": 75.05,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "75 y.o. with a. fib, cva, migraines, vertigo, ptsd, htn here with focusing issues. having a sensation behind the eye that feels like he cannot focus well. intermittent transient blurring of vision - reassuring exam and testing > try treating with artificial tears > warm compresses combined cataract ou - not visually significant > observe refractive error > updated glasses prescription given follow up DATE_TIME, mrx, dilate",
"gpt4_summary": "75 y.o. patient presents with focus issues, intermittent blurred vision. Examined for glaucoma - results reassuring. Plan: artificial tears, warm compresses, updated glasses prescription.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09192",
"image_path": "slo_fundus_09192.jpg",
"filename": "data_09192.npz",
"report": "Patient has mild stage primary open-angle in both eyes and is a low risk glaucoma suspect. No history of trauma, kidney disease or asthma. No known allergies to glaucoma medications. Presence of dry eye syndrome and incipient cataracts in both eyes. Intraocular pressure (IOP) goals <= 21 mmhg. Follow-up planned.",
"age": 41.41,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "attending's assessment: 1. primary open-angle, mild stage, both eyes versus glaucoma suspect, low risk, both eyes family history of glaucoma: mother, 3 maternal aunts, maternal grandmother no history of asthma, trauma or kidney disease. +reports history of NRP steroids during allergy injections while in college, only used for DATE_TIME at a time. central corneal thickness (cct - DATE_TIME): 550/562 tmax (maximum intraocular pressure recorded: 16/14 iop (DATE_TIME): 15/15 mmhg iop (DATE_TIME): 14/12 mmhg iop (DATE_TIME): 12/12 mmhg gonioscopy (DATE_TIME): od: open os: open allergies to glaucoma medications: none known prior intraocular surgeries: none prior history of lasers: none last hvf (DATE_TIME): od: stable and full os: stable and full last oct rnfl (DATE_TIME): od: average thickness 86 microns, stable with superior thinning os: average thickness 84 microns, stable DATE_TIME gcc (DATE_TIME): od: baseline os: baseline baseline optic disc photos: DATE_TIME 2. dry eye syndrome, both eyes -preservative-free artificial tears as needed. 3. incipient cataracts, both eyes -not visually significant as of DATE_TIME. 4. social/systemic issues: rn in k-8 school in LOCATION. prior patient of dr. hoguet's. attending's plan: -goal intraocular pressure less than or equal to 21 mmhg, right eye -goal intraocular pressure less than or equal to 21 mmhg, left eye -iop at goal ou on DATE_TIME off glaucoma medications. -continue close monitoring off glaucoma medications. -preservative-free artificial tears as needed. -follow-up in DATE_TIME with iop check, hvf, dilation, and disc photos ou, sooner prn.",
"gpt4_summary": "Patient has mild stage primary open-angle in both eyes and is a low risk glaucoma suspect. No history of trauma, kidney disease or asthma. No known allergies to glaucoma medications. Presence of dry eye syndrome and incipient cataracts in both eyes. Intraocular pressure (IOP) goals <= 21 mmhg. Follow-up planned.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09199",
"image_path": "slo_fundus_09199.jpg",
"filename": "data_09199.npz",
"report": "The patient has a history of hyphema in the right eye due to an exercise band accident. Gonioscopy shows more than a 180-degree recession. HVF, OCT, and CCT results are normal.",
"age": 26.52,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "imp: h/o hyphema od due to exercise band to DATE_TIME angle recession od with >180 degrees recession on gonioscopy - last hvf and DATE_TIME normal, previously followed by dr. PERSON then PERSON, DATE_TIME --today normal hvf ou; oct of rnfl unremarkable (borderline sup rnfl PERSON); cct 559/578 floaters od --rd s&s disc plan: yrly with repeat hvf and oct",
"gpt4_summary": "The patient has a history of hyphema in the right eye due to an exercise band accident. Gonioscopy shows more than a 180-degree recession. HVF, OCT, and CCT results are normal.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09201",
"image_path": "slo_fundus_09201.jpg",
"filename": "data_09201.npz",
"report": "The patient is suspected to have glaucoma due to cup to disc ratio in both eyes. However, no thinning found in retinal nerve fiber layers. Earlier elevated intraocular pressure (IOP) may have been incorrect. Currently, IOP is within acceptable range without treatment. Patient also has mild, non-significant cataracts.",
"age": 53.62,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "first seen by dr. PERSON on DATE_TIME glaucoma medication intolerances: none target iop: DATE_TIME, tmax: 23 / 21 central corneal thickness: 531 / 545 gonioscopy: c35f, 1+ ptm ou retinal nerve fiber layer, right eye: no thinning retinal nerve fiber layer, left eye: no thinning visual fields, right eye: grossly full, mild inferior depression, does not correspond to oct/nerve visual fields, left eye: grossly full, mild superior depression, does not correspond to oct/nerve family history: mother steroids: none trauma: none asthma/copd: none other medical history and problems: htn assessment/plan: 53 y.o. female # questionable ocular hypertension, glaucoma suspect due to cup to disc ratio, both eyes - dr. PERSON started PERSONE - oct without thinning, earlier elevated iop may have been spurious due to squeezing with tonopen, was listed as 27/23 prior to applanation DATE_TIME during same visit - iop acceptable ou after stopping latanoprost qhs ou - continue to monitor without resuming treatment - return in DATE_TIME for iop check, dilate # cataract, both eyes - mild, not visually significant, monitor PERSON, md",
"gpt4_summary": "The patient is suspected to have glaucoma due to cup to disc ratio in both eyes. However, no thinning found in retinal nerve fiber layers. Earlier elevated intraocular pressure (IOP) may have been incorrect. Currently, IOP is within acceptable range without treatment. Patient also has mild, non-significant cataracts.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09203",
"image_path": "slo_fundus_09203.jpg",
"filename": "data_09203.npz",
"report": "The patient has inadequately controlled pressure in their right eye. Despite medication, their intraocular pressure (IOP) is consistently high. They've had a cataract grow in the same eye leading to a narrower angle. They've undergone phaco/ecp/kdb treatment. There is potential for YAG Capsulotomy in the future. Glaucoma not mentioned.",
"age": 74.5,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "unknown",
"note": "medications. her angle in the right eye also is more narrow due to the cataract. we discussed that we will add rhopressa qhs od for now and we should proceed with LOCATION/PERSON given her pressure is inadequately controlled. -long discussion with patient on DATE_TIME: given iop persistently above goal od despite addition of rhopressa and cataract that has grown od leading to narrow angle od, we proceeded with phaco/ecp/kdb od on DATE_TIME. -mrx given at patient's request on DATE_TIME. -rtc in DATE_TIME with iop check ou, PERSON (with coaching), and disc photos ou, sooner prn. we may consider yag capsulotomy os in future if mrx isn't 20/30 or better. the information above was documented by PERSON as a scribe for PERSON on DATE_TIME.",
"gpt4_summary": "The patient has inadequately controlled pressure in their right eye. Despite medication, their intraocular pressure (IOP) is consistently high. They've had a cataract grow in the same eye leading to a narrower angle. They've undergone phaco/ecp/kdb treatment. There is potential for YAG Capsulotomy in the future. Glaucoma not mentioned.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09204",
"image_path": "slo_fundus_09204.jpg",
"filename": "data_09204.npz",
"report": "The clinical note does not provide specific details about the patient's condition, including the presence or absence of glaucoma.",
"age": 79.76,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "resident/fellow. i have reviewed the resident/fellow's notes and made any necessary changes. i, PERSON, am acting as scribe for PERSONmd, PERSON for patient PERSON on DATE_TIME.",
"gpt4_summary": "The clinical note does not provide specific details about the patient's condition, including the presence or absence of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09206",
"image_path": "slo_fundus_09206.jpg",
"filename": "data_09206.npz",
"report": "The patient has dysfunction in the left vestibular nuclei and persistent lesions in the left lateral medulla. Her oscillopsia results from unilateral vestibular loss. No mention of glaucoma.",
"age": 29.07,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "showed no enhancing lesions. the left vestibular function is likely related to dysfunction in the left vestibular nuclei, and she has some chronic flair lesions in the left lateral medulla. her oscillopsia with movement is related to unilateral vestibular loss and failure to appropriately compensate. it therefore differs from oscillopsia from pendular nystagmus and is less amenable to medical treatment. we discussed there is a possibility that her brain could begin to compensate over time or that the unilateral vestibular loss could improve as myelination recovers. recommendations: 1. see local optometrist for refraction, possibly eye glasses ?2. return in DATE_TIME to see me for visual field, oct on DATE_TIME i spent a total of DATE_TIME reviewing the electronic medical record, taking an updated history, performing a physical exam, reviewing mri brain from DATE_TIME, interpreting the oct and visual field testing, discussing the findings and treatment plan with ms. PERSON, and documenting the clinical encounter. PERSON, LOCATION.",
"gpt4_summary": "The patient has dysfunction in the left vestibular nuclei and persistent lesions in the left lateral medulla. Her oscillopsia results from unilateral vestibular loss. No mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09207",
"image_path": "slo_fundus_09207.jpg",
"filename": "data_09207.npz",
"report": "The patient is a 55-year-old attorney with a history of hyperlipidemia, depression, ADHD, benign familial tremor, and has been treated for dense brunescent cataract and mac-off rd. Auter has a strong dry surface, pigment dispersion syndrome, and hx erm; wear of contact lenses has also been resolved. Has no glaucoma but will start anti-hypertensive ocular medication.",
"age": 55.87,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "55 yo attorney with history of hyperlipidemia, depression, adhd, benign familial tremor, PERSON with me DATE_TIME. s/p phaco/pciol od DATE_TIME of dense brunescent cataract. +hx LOCATION, 2+ifis/lidrs. +very deep brow ls is only composite declined toric due to expense. has very dry surface >> treated with at and aware des will impact final va >> DATE_TIME: collagen plug (eagle 0.3) placed LOCATION, continue pfat. change to name-brand pf qid taper. no ilevro (never started). refresh pm at least qhs, more if possible >> DATE_TIME: updated mrx DATE_TIME. cortical cataract os -mild progression since DATE_TIME, now in axis 3. s/p ppv od DATE_TIME for mac-off rd extending from DATE_TIME, tear DATE_TIME (dr. PERSON, LOCATION) 4. PERSONME for subclinical rd os with single break 5. pigment dispersion syndrome ou tmax 18/21. cct 561/590 (ave/thick). PERSON (maternal gmo) hvf DATE_TIME: od fixation losses, inferior arcuate. os full hvf DATE_TIME: od full. os subthreshold losses inferiorly, no progression hvf with inferior losses in past, full DATE_TIME for 2nd test in row DATE_TIME: od superior thinning, os grossly full DATE_TIME: od missing data. os superior thinning, different machine but appears worse c/w normative database DATE_TIME oct DATE_TIME: ou wnl (but decr signal PERSON) PERSON ou 10/06 >> DATE_TIME: has had monitoring q6 DATE_TIME while in LOCATION, no LOCATION, last hvf approx DATE_TIME, reports iop have not been elevated. >> will start ocular anti-htn. has pds, depression. will try PERSON ou bid, check iop, gonio, repeat testing 6. history of ctl overwear no contacts since DATE_TIME. resolved micropannus ou. wants to return to ctl as of DATE_TIME -more recently wearing toric ctl until DATE_TIME (didn't want expense, vision was declining) 7. pvd ou 8. hx erm ou -noted at least in DATE_TIME os, poor view od pre-op DATE_TIME DATE_TIME: erm od > os but with preserved foveal contour ou",
"gpt4_summary": "The patient is a 55-year-old attorney with a history of hyperlipidemia, depression, ADHD, benign familial tremor, and has been treated for dense brunescent cataract and mac-off rd. Auter has a strong dry surface, pigment dispersion syndrome, and hx erm; wear of contact lenses has also been resolved. Has no glaucoma but will start anti-hypertensive ocular medication.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09212",
"image_path": "slo_fundus_09212.jpg",
"filename": "data_09212.npz",
"report": "The patient has ocular hypertension in both eyes with slightly narrow angles. The pressure increased after dilation. No sign of glaucoma but medication for hypertension initiated. Cataracts noted.",
"age": 72.46,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "may DATE_TIME, DATE_TIME PERSON, PERSON joslin place LOCATION ma 02215 patient: PERSON mr number: NUMBER date of birth: DATE_TIME date of visit: DATE_TIME dear dr. PERSON: thank you for referring PERSON to me for evaluation. below are the relevant portions of my note. if you have questions, please do not hesitate to call me. i look forward to following PERSON along with you. sincerely, PERSONon, PERSON no recipients visual acuity (snellen - linear) right left dist cc PHONE_NUMBER dist ph cc PHONE_NUMBER correction: glasses tonometry tonometry (applanation, DATE_TIME) right left pressure 26 23 tonometry #2 (after dil, DATE_TIME) right left pressure 35 25 main ophthalmology exam external exam right left external normal normal slit lamp exam right left lids/lashes normal normal conjunctiva/sclera normal normal cornea normal normal anterior chamber slightly shallow slightly shallow iris normal normal lens 1+ nuclear sclerosis 1+ nuclear sclerosis vitreous normal normal fundus exam right left disc rim intact, small on rim intact, small on c/d ratio 0.4 0.4 macula normal normal vessels normal normal periphery nl, dfe 5/16 nl, dfe 5/16 attending's assessment and plan: - ocular hypertension ou, angles slightly narrow w iop inc after dil ou. PERSON. PERSON. medication intolerance: none central corneal thickness: 509/ 519 goal PERSON around 20, os around 20 plan: c/w xal ou qhs. - drop of LOCATION given ou in the office - may need lpi in the future vs ce given iop elev after dil. - add timolol ou qam - cataracts, nvs plan: per dr. sharuk - systemic / social issues: no dm. y - rtc in 2 mo for iop ou and oct ou.",
"gpt4_summary": "The patient has ocular hypertension in both eyes with slightly narrow angles. The pressure increased after dilation. No sign of glaucoma but medication for hypertension initiated. Cataracts noted.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09213",
"image_path": "slo_fundus_09213.jpg",
"filename": "data_09213.npz",
"report": "The patient has chronic angle closure glaucoma with intraocular pressure in 20-24 range in both eyes. Prior treatment includes laser peripheral iridotomy. Currently on latanoprost, previously timolol, recommending cataract extraction.",
"age": 66.51,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "married or partnered",
"note": "first seen by PERSONn DATE_TIME diagnosis: chronic angle closure glaucoma. s/p laser peripheral iridotomy DATE_TIME both eyes. on 2 drops with intraocular pressure in 20-24 range both eyes. target iop: / , tmax: 25 (outside records) / 30 (outside records) central corneal thickness: 597 / 581 gonioscopy: appositionally closed, peripheral anterior synechiae both eyes refractive error: od . . / os . . optic nerve findings on initial visit right eye: average retinal nerve fiber layer 87um optic nerve findings on initial visit left eye: average retinal nerve fiber layer 95 um visual fields on initial visit right eye: non-specific defects, borderline reliability visual fields on initial visit left eye: non-specific defects, borderline reliability medication history and intolerances at first visit: on latanoprost and timolol (ran out of timolol so not currently using) glaucoma procedures right eye: laser peripheral iridotomy DATE_TIME glaucoma procedures left eye: laser peripheral iridotomy DATE_TIME other eye procedures right eye: none other eye procedures left eye: none other eye problems right eye: cataract other eye problems left eye: cataract family history: no steroids: no trauma: no asthma: no other medical history and problems: arthritis plan: initial note: PERSON both eyes intraocular pressure 20 right eye and 21 left eye on latanoprost (ran out of timolol DATE_TIME) optical coherence tomography within normal limits both eyes, humphrey visual field with borderline reliability and non-specific defects gonioscopy shows peripheral anterior synechiae and occludible angles, pi patent in both eyes recommend cataract extraction/iol both eyes continue latanoprost both eyes. also refilled timolol given borderline intraocular pressure DATE_TIME and history of intraocular pressure 20-24 range at outside provider on both drops",
"gpt4_summary": "The patient has chronic angle closure glaucoma with intraocular pressure in 20-24 range in both eyes. Prior treatment includes laser peripheral iridotomy. Currently on latanoprost, previously timolol, recommending cataract extraction.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09215",
"image_path": "slo_fundus_09215.jpg",
"filename": "data_09215.npz",
"report": "The note mentions medications including dorzolamide-timolol, furosemide, latanoprost etc., mainly for eye disorders and heart conditions. Patient does have glaucoma, amongst other conditions like Parkinson's, heart diseases etc.",
"age": 83.87,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "dorzolamide-timolol (cosopt) 22.3-6.8 mg/ml ophthalmic solution place 1 drop into the left eye 2 (two) times a day. furosemide (lasix) 20 mg tablet take 1 tablet (20 mg total) by mouth DATE_TIME. latanoprost (xalatan) 0.005 % ophthalmic solution place 1 drop into the left eye every evening. PERSON succinate (toprol-xl) 25 mg 24 hr tablet take 1 tablet (25 mg total) by mouth DATE_TIME. multivitamin per tablet take 1 tablet by mouth DATE_TIME. PERSON, md, phd DATE_TIME PERSON pegwar DATE_TIME 4:12 am metal med transfer process pimavanserin (nuplazid) 17 mg tablet take 2 tablets (34 mg total) by mouth DATE_TIME. facility administered medications metoprolol succinate (toprol-xl) er tablet 25 mg take 0.5 tablets (25 mg total) by mouth DATE_TIME. your orders future appointments provider department dept phone DATE_TIME PERSON echo 3 (cupid) PERSON cardiac us DATE_TIME PERSON, PERSONtitution cardiology division DATE_TIME DATE_TIME PERSON y hung, md, LOCATION; Institution neuro room 25 Institution department of neurology DATE_TIME 8:10 am PERSON, PERSONtitution glaucoma main campus PHONE_NUMBER condition list as of DATE_TIME parkinson's disease arteriosclerotic heart disease glaucoma hypertensive disorder dysphagia aortic valve disorder hyperlipidemia edema of lower extremity carotid atherosclerosis perforated corneal ulcer post-operative state results summary immunizations administered on date of encounter - DATE_TIME none",
"gpt4_summary": "The note mentions medications including dorzolamide-timolol, furosemide, latanoprost etc., mainly for eye disorders and heart conditions. Patient does have glaucoma, amongst other conditions like Parkinson's, heart diseases etc.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09216",
"image_path": "slo_fundus_09216.jpg",
"filename": "data_09216.npz",
"report": "Patient shows signs of potential glaucoma with presence of eye cupping. Family history of glaucoma present. No treatment necessary yet. Also has nuclear sclerosis, floaters and refractive error.",
"age": 65.97,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "imp: cupping ou, susp for glaucoma fhx+ paternal grandmother iop DATE_TIME cct 580/582 hvf full ou oct reassurring with borderline nasal thinning od only. observe off treatment f/u DATE_TIME iop check nuclear sclerosis ou pvd (floater) ou refr error plan: rx=m glasses i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow. i have reviewed the resident/fellow's notes and made any necessary changes.",
"gpt4_summary": "Patient shows signs of potential glaucoma with presence of eye cupping. Family history of glaucoma present. No treatment necessary yet. Also has nuclear sclerosis, floaters and refractive error.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09221",
"image_path": "slo_fundus_09221.jpg",
"filename": "data_09221.npz",
"report": "51-year-old patient has diabetes mellitus, hypothyroidism but no diabetic retinopathy. Showed optic disc cupping, abnormality often seen in glaucoma, in one eye. No immediate intervention recommended.",
"age": 51.67,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "51 y.o. est patient with dm, hypothyroidism # type 2 diabetes mellitus with no diabetic retinopathy ou hemoglobin a1c date value ref range status DATE_TIME (h) 4.2 - 5.6 % final comment: hba1c levels 5.7-6.4% represent pre-diabetes, indicating impaired glucose control and an increased risk of developing diabetes. the diagnostic hba1c level for diabetes is 6.5% or greater. hba1c is performed by the roche tina-quant immunoassay method which does not detect (incidental) hemoglobin variants. hemoglobin electrophoresis should be ordered in patients with suspected hemoglobinopathies. > importance of blood pressure, blood sugar and lipid control emphasized > yearly exams # optic disc cupping os> od - + family hx, father and PERSON 22 ou - photos - cct DATE_TIME DATE_TIME 100/94 wnl both eyes DATE_TIME 98/95 wnl both eyes - hvf DATE_TIME full both eyes DATE_TIME nonspecific defects > observe, no indication for intervention at this time. repeat testing in a year # refractive error > updated glasses prescription given for reading last visit, no significant change stable exam fu DATE_TIME, mrx, dilate, hvf/ oct",
"gpt4_summary": "51-year-old patient has diabetes mellitus, hypothyroidism but no diabetic retinopathy. Showed optic disc cupping, abnormality often seen in glaucoma, in one eye. No immediate intervention recommended.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09224",
"image_path": "slo_fundus_09224.jpg",
"filename": "data_09224.npz",
"report": "The note mentions the presence of glaucoma requiring treatment with multiple medications including latanoprost, rhopressa, diamox, cosopt, and brimonidine. The patient also has a significant cataract and high intraocular pressure in both eyes.",
"age": 74.69,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "latanoprost qhs ou, rhopressa qhs os, diamox 125 mg PERSON, cosopt bid os, brimonidine bid os, and s/p phaco/ecp/kdb od. -start latanoprost qhs ou (from qhs os only). -continue rhopressa qhs os only. -continue diamox 125 mg po qhs for sleep apnea (not for glaucoma). -continue cosopt bid os. -start brimonidine bid os. -hold brimonidine bid od. -hold PERSON. -emphasized adherence to medication regimen. -instructions written/typed/printed out for patient (see table/details under patient instructions). -encouraged tight blood glucose, blood pressure and blood cholesterol control -preservative-free artificial tears as needed. -mrx given at patient's request on DATE_TIME. -follow-up with dr. PERSON-gerogiannis for general eye care. -long discussion with patient on DATE_TIME: given visually-significant cataract od and need for 6 agents for iop control, we proceeded with phaco/ecp/kdb od on DATE_TIME. -rtc in DATE_TIME with iop check, hvf (with coaching), dilation, and oct rnfl/gcc ou, sooner prn. consider ecp/kdb os in the future if good result persists od => aiming to book surgery os before he goes away at DATE_TIME. the information above was documented by Person as a scribe for PERSON on DATE_TIME. i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate. fellow a/p repeat automated perimetry confirmed change od, stable os retinal nerve fiber layer/gcc stable intraocular pressure too high right eye, too high left eye recommend continue latanoprost 1/1, rhopressa 0/1, change dorzolamide/timolol 2/2, brimonidine 2/2 return to clinic intraocular pressure check in DATE_TIME",
"gpt4_summary": "The note mentions the presence of glaucoma requiring treatment with multiple medications including latanoprost, rhopressa, diamox, cosopt, and brimonidine. The patient also has a significant cataract and high intraocular pressure in both eyes.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09227",
"image_path": "slo_fundus_09227.jpg",
"filename": "data_09227.npz",
"report": "35-year-old male, with a history of POTS and small fiber neuropathy, is a suspect for glaucoma based on increased C:D ratio OU. The patient stopped using Flonase, which stabilized his IOP. He suffers migraines with visual auras and occasional tunnel vision. He experiences floaters in his eyes and difficulty with night vision. He has been prescribed new glasses and is scheduled for a 6-month check.",
"age": 35.53,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "35 y.o. male h/o pots and small fiber neuropathy 1. glaucoma suspect based on inc c:d ratio ou, PERSON (DATE_TIME on flonase) likely steroid responder hvf full oct wnl and stable ou dp stable pt stopped flonase DATE_TIME, iop now controlled ou observe 2. migraine with visual aura first episode: DATE_TIME two episodes in DATE_TIME DATE_TIME: tunnel vision (DATE_TIME) followed by headache afterwards resolved with asa left sided numbness, stumbling (neurologic sx lasted < DATE_TIME and resolved)\u00ff DATE_TIME: episode of central blind spot in vision with zigzag rainbow oil/water mixture around edge lasted DATE_TIME and resolved + headache followed (and headache continues), no other neurologic sx. now bothered by migraines and brain zap sx, seeing neurologist, tried topamax but stopped due to increase in has 3. floaters ou, PERSON, chronic, no tob dust/retinal tears/rd rd warnings 4. refractive error: a prescription for new glasses was given to the patient DATE_TIME. 5. c/o night vision trouble can't drive well at DATE_TIME can't see other things that other people can retina eval color wnl ou 6 mo check mrx, iop (by md)",
"gpt4_summary": "35-year-old male, with a history of POTS and small fiber neuropathy, is a suspect for glaucoma based on increased C:D ratio OU. The patient stopped using Flonase, which stabilized his IOP. He suffers migraines with visual auras and occasional tunnel vision. He experiences floaters in his eyes and difficulty with night vision. He has been prescribed new glasses and is scheduled for a 6-month check.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09229",
"image_path": "slo_fundus_09229.jpg",
"filename": "data_09229.npz",
"report": "74-year-old woman suspect for primary open angle glaucoma due to cup:disc asymmetry; disc hemorrhage in left eye observed. Has family history of glaucoma. Both eyes have cataracts, but not significant.",
"age": 75.02,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "74 LOCATION wf, referred by dr. PERSON for glaucoma eval h/o disc heme os on retinal exam 1. primary open angle glaucoma suspect based on cup:disc asymmetry od refer to retina for eval pinguecula ou - artificial tears - sunglasses when outdoors refractive error > updated glasses prescription given",
"gpt4_summary": "61 y.o. patient with hyperlipidemia and weight loss sees intermittent vertical black line. Has lamellar hole in both eyes. No glaucoma mentioned.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09238",
"image_path": "slo_fundus_09238.jpg",
"filename": "data_09238.npz",
"report": "Patient with cataract and posterior vitreous detachment. Suspicion for glaucoma due to cupping, but no confirmed history of IOP elevation. Occasional thinning in retina.",
"age": 73.01,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "imp: cataract ou pvd ou cupping ou, susp for glaucoma, but PERSON; no hx iop elev; stable oct with focal borderline rnfl thinning od; nl rnfl os; unrel hvf ou (falling asleep) refr error plan: rx=m yrly with hvf and oct",
"gpt4_summary": "Patient with cataract and posterior vitreous detachment. Suspicion for glaucoma due to cupping, but no confirmed history of IOP elevation. Occasional thinning in retina.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09241",
"image_path": "slo_fundus_09241.jpg",
"filename": "data_09241.npz",
"report": "The patient, a 63-year-old male, has primary open-angle glaucoma (POAG) based on increased cup-to-disc ratio, but no history of elevated intraocular pressure. He has never been treated before, family history is negative. OCT and HVF were normal. The intraocular pressure is under control. The patient also has a mild, non-visually significant cataract. The plan is regular observation, discussion of glaucoma risk, and periodic testing. He can use over-the-counter readers +2.50.",
"age": 63.87,
"gender": "male",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "63 y.o. male 1. poag(s) based on inc c:d ratio ou no h/o elevated iop has been checked with testing in the past, never treated fhx negative hvf full ou oct wnl ou cct thick ou (605, 611) iop controlled ou plan: observe discussed risk of glaucoma and need for DATE_TIME testing 2. mild cataract is present ou that is not visually significant. observation at this time was recommended. 3. re - mrx given or may use otc readers +2.50 DATE_TIME, mrx, iop, hvf, LOCATION, oct and dp",
"gpt4_summary": "The patient, a 63-year-old male, has primary open-angle glaucoma (POAG) based on increased cup-to-disc ratio, but no history of elevated intraocular pressure. He has never been treated before, family history is negative. OCT and HVF were normal. The intraocular pressure is under control. The patient also has a mild, non-visually significant cataract. The plan is regular observation, discussion of glaucoma risk, and periodic testing. He can use over-the-counter readers +2.50.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09242",
"image_path": "slo_fundus_09242.jpg",
"filename": "data_09242.npz",
"report": "The patient has type II diabetes with an A1C value at the upper end of the normal range, suggesting good control. They are a glaucoma suspect with a pituitary adenoma, anterior stromal scar of unclear origin and pingueculae. They also have seasonal allergies and dry eye.",
"age": 32.77,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "married or partnered",
"note": "dm ii hemoglobin a1c date value ref range status DATE_TIME 5.6 4.2 - 5.6 % final comment: hba1c levels 5.7-6.4% represent pre-diabetes, indicating impaired glucose control and an increased risk of developing diabetes. the diagnostic hba1c level for diabetes is 6.5% or greater. hba1c is performed by the roche tina-quant immunoassay method which does not detect (incidental) hemoglobin variants. hemoglobin electrophoresis should be ordered in patients with suspected hemoglobinopathies. pituitary adenoma hvf 24-2 full and reliable ou 30-2 to be done next visit anterior stromal scar od unclear origin pingueculae ou nasally and temporally ou encouraged ats prn glaucoma suspect PERSON, onh and PERSON, tcorr +4/+4 seasonal allergy allergy and dry eye handout given and explained. recommend pataday for allergy season. at's prn. no heat, no rubbing during allergy season. PERSON shows minimal myopic, but takes no refraction excellent vision ou follow up with me in DATE_TIME for routine exam by signing my name below, i, PERSON, md, acting as a scribe, attest that this documentation has been prepared under the direction and in the presence of PERSON, LOCATION DATE_TIME DATE_TIME",
"gpt4_summary": "The patient has type II diabetes with an A1C value at the upper end of the normal range, suggesting good control. They are a glaucoma suspect with a pituitary adenoma, anterior stromal scar of unclear origin and pingueculae. They also have seasonal allergies and dry eye.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09245",
"image_path": "slo_fundus_09245.jpg",
"filename": "data_09245.npz",
"report": "The 59-year-old male patient has a history of various health issues and is currently seeking a second opinion on ocular hypertension. His intraocular pressure (IOP) is elevated at 28-30 mmHg. This, along with family history and other symptoms, makes him a suspect for glaucoma.",
"age": 59.79,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "59 yo man director of special education for nh state prisons with history of bcc r temple DATE_TIME arthritis, irritable bowel, sinus issues new patient DATE_TIME DATE_TIME, here for 2nd opinion on ocular htn. reports he's always had elevated iop around 26-28, but most recently 28-30 mmhg and discussed starting PERSON 1. glaucoma suspect od>os ta 30/29 DATE_TIME. cct DATE_TIME 575/563 (thick/ave). PERSON (father, also may have had amd, deceased) gonio DATE_TIME: cbb 360' ou hvf DATE_TIME: full ou oct DATE_TIME: od is thinning. os superior and borderline it thinning >> discussed findings, 14% ohts risk over DATE_TIME. given fhx, c/d and iop will start txe ou qam and check iop in DATE_TIME would like to continue care here onh photos on f/u with NRP and iop check",
"gpt4_summary": "The 59-year-old male patient has a history of various health issues and is currently seeking a second opinion on ocular hypertension. His intraocular pressure (IOP) is elevated at 28-30 mmHg. This, along with family history and other symptoms, makes him a suspect for glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09247",
"image_path": "slo_fundus_09247.jpg",
"filename": "data_09247.npz",
"report": "Patient has stable inferior thinning in the right eye (OD). Treatments with latanoprost were started, stopped and resumed, with patient's intraocular pressure (IOP) monitored. However, hierarchal visual field changes in the left eye (OS) led to resumption of latanoprost. Patient suffered from loss to follow-up and interrupted treatment. Currently, visual field and retinal pigment epithelium status are stable. The patient has asymptomatic pterygium and retinal pigment epithelium changes, with advice given on healthy lifestyle. No evidence of glaucoma mentioned.\n",
"age": 85.96,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "stable DATE_TIME: od inferior thinning, stable. PERSON (tr thinner) 1st DATE_TIME: od inferior thinning, os normal 1st oct DATE_TIME: od inferior thinning. PERSON st thinning \u00ff >> iop stable DATE_TIME, but 2nd reliable hvf showing reproducible superior paracentral depression c/w inferior onh thinning od >> started latanoprost ou qhs but stopped after DATE_TIME on his own DATE_TIME: resumed latanoprost, f/u check iop DATE_TIME and hvf DATE_TIME: overall stable but given hvf changes os with iop sl higher os than od, restart latanoprost qhs ou for now (pt didn't call for refill DATE_TIME, again reminded to refill) DATE_TIME: lost to f/u until now. ran out of PERSON and stopped latanoprost at least 6 months now. hvf od stable, os sl denser but more compact central depression (likely due to dry amd os>od as oct stable ou). resume latanoprost DATE_TIME: testing stable, continue latanoprost \u00ff 5. pterygium ou -asymptomatic, monitor \u00ff 6. pvd ou -rd precautions reviewed \u00ff 7. rpe changes os>>od - oct obtained DATE_TIME DATE_TIME: rpe irregularity ou >> counseled re healthy lifestyle. non-smoker \u00ff",
"gpt4_summary": "Patient has stable inferior thinning in the right eye (OD). Treatments with latanoprost were started, stopped and resumed, with patient's intraocular pressure (IOP) monitored. However, hierarchal visual field changes in the left eye (OS) led to resumption of latanoprost. Patient suffered from loss to follow-up and interrupted treatment. Currently, visual field and retinal pigment epithelium status are stable. The patient has asymptomatic pterygium and retinal pigment epithelium changes, with advice given on healthy lifestyle. No evidence of glaucoma mentioned.\n",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09250",
"image_path": "slo_fundus_09250.jpg",
"filename": "data_09250.npz",
"report": "Patient has glaucoma, with medication intolerances due to pain and herpetic infection concerns. They also have corneal edema, anxiety, htn, hld, hypothyroidism, migraines, and osa. Treatment options considered are beta blockers and possible surgery.",
"age": 57.68,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "first seen by dr. PERSON on DATE_TIME (previously followed by dr. PERSON) glaucoma medication intolerances: PERSON (pain), avoiding pgas given concern for herpetic infection, avoiding dorzolamide due to corneal edema target iop: DATE_TIME, tmax: 25 / 13 central corneal thickness: 599 / 532 gonioscopy: od: heavy pas inferiorly and nasally, c30f 2+ superiorly/temporally; os: c30f 2+ retinal nerve fiber layer, right eye: full retinal nerve fiber layer, left eye: full visual fields, right eye: generalized depression, nonspecific defects visual fields, left eye: full, nonspecific defects family history: father, brother requiring surgery steroids: topical right eye trauma: none asthma/copd: asthma other medical history and problems: anxiety, htn, hld, hypothyroidsm, migraine, osa assessment/plan: 57 y.o. female # primary angle closure, right eye - etiology of very asymmetric pas and corneal edema unclear, possible ice syndrome spectrum? - iop borderline od and acceptable os on brimonidine bid od - continue brimonidine bid os; could potentially add betaxolol bid od in future if necessary - ok to proceed with phaco/dmek od from glaucoma standpoint, would maybe benefit from slight goniosynechialysis at that time - return in DATE_TIME for iop check, dilate, disc photos # corneal edema, right eye - on acyclovir 400mg bid maintenance, prednisolone bid od, PERSON had kontur lens 8.6/16 placed DATE_TIME for pain, on moxifloxacin bid od - dr. jurkunas planning for phaco/dmek od # cataract, both eyes - approaching visual significance faith LOCATION, PERSON saw and evaluated this patient and discussed the case as appropriate with the resident/fellow. i have reviewed the resident/fellow's notes and made any necessary changes. PERSON, md",
"gpt4_summary": "Patient has glaucoma, with medication intolerances due to pain and herpetic infection concerns. They also have corneal edema, anxiety, htn, hld, hypothyroidism, migraines, and osa. Treatment options considered are beta blockers and possible surgery.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09252",
"image_path": "slo_fundus_09252.jpg",
"filename": "data_09252.npz",
"report": "78 yo patient with diabetes and hypertension has no light perception vision OS, possible previous acute angle closure OS with attempted surgical repair. Ocular hypertension is okay, but further glaucoma testing scheduled.",
"age": 79.11,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "spanish",
"maritalstatus": "single",
"note": "78 yo with dm, hypertension seen by dr. PERSON previously \u00ff\u00ff s/p complex phaco/pciol with trypan od , aim -0.25 DATE_TIME temporal wound, shallow chamber, stop and chop, no complications - doing well > updated glasses rx given (polycarbonate), encouraged to wear full time given monocular status \u00ff\u00ff\u00ff no light perception vision os: longstanding per patient, DATE_TIME; suspect prior episode of acute angle closure os with attempted surgical repair; patent pi for narrow angle od; no posterior view os. PERSON done 6/13: PERSON -follow, no pain \u00ff\u00ff allergic conjunctivitis: mild -patanol bid ou -warm compresses bid -artificial tears prn \u00ff\u00ff refractive: rx given \u00ff\u00ff ocular hypertension: iop ok DATE_TIME - cct 498/480 - hvf od borderline reliable, paracentral scotoma, scattered defects - oct od inf thinning, PERSON > observe for now, repeat hvf/ oct in 6 months\u00ff fu DATE_TIME, iop check, glaucoma testing, hvf, oct (od only)",
"gpt4_summary": "78 yo patient with diabetes and hypertension has no light perception vision OS, possible previous acute angle closure OS with attempted surgical repair. Ocular hypertension is okay, but further glaucoma testing scheduled.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09254",
"image_path": "slo_fundus_09254.jpg",
"filename": "data_09254.npz",
"report": "Patient has cupping in both eyes, not glaucoma as per HVF & OCT tests. Also has thick CCT, mild cataract, and refractive error.",
"age": 68.02,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "imp: cupping ou; not glaucomatous by hvf and oct now; thick cct mild cataract ou refr error plan: rx=m prn yrly with hvf and oct",
"gpt4_summary": "Patient has cupping in both eyes, not glaucoma as per HVF & OCT tests. Also has thick CCT, mild cataract, and refractive error.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09255",
"image_path": "slo_fundus_09255.jpg",
"filename": "data_09255.npz",
"report": "29 y.o. male patient with pre-perimetric juvenile open-angle glaucoma in both eyes, treated with SLT in the left eye. Noted early nasal thinning, stable condition, but higher IOP than previous baseline. Uses Cosopt, mild papillary conjunctivitis improved after stopping Alphagan.",
"age": 29.02,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "29 y.o. m prev. followed by PERSON, then dr. song 1. pre-perimetric juvenile open-angle glaucoma ou s/p slt os DATE_TIME cct 580/570; tm 40 mmhg ou; superimposed upon congenitally anomalous ons - h/o alphagan allergy - s/p slt os (DATE_TIME) - oct-rnfl (88/87) with early nasal thinning os; remains stable - hvf full ou; stable - iop remains higher than previous baseline of mid teens ou; but no change on oct or hvf - tg <= 21 ou reasonable; above goal DATE_TIME ou despite compliance 2. history of mild papillary conjunctivitis ou - improved since stopping alphagan and using PERSON pf cosopt as above social/systemic: soft cl wearer (occasionally) plan continue cosopt pf bid ou DATE_TIME iop check t/c latanoprost or LOCATION if iop still high",
"gpt4_summary": "29 y.o. male patient with pre-perimetric juvenile open-angle glaucoma in both eyes, treated with SLT in the left eye. Noted early nasal thinning, stable condition, but higher IOP than previous baseline. Uses Cosopt, mild papillary conjunctivitis improved after stopping Alphagan.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09256",
"image_path": "slo_fundus_09256.jpg",
"filename": "data_09256.npz",
"report": "Patient exhibits disc asymmetry and borderline intraocular pressures (19,22). Glaucoma not confirmed. Will return for intraocular pressure check and tests.",
"age": 55.72,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "imp: disc asymmetry and borderline pressures (19,22 DATE_TIME), as before normal/stable hvf ou; stable oct; angles open by gonio refr error plan: rx=m glasses as iop is up slightly DATE_TIME, rv in DATE_TIME for iop check and repeat hvf and oct",
"gpt4_summary": "Patient exhibits disc asymmetry and borderline intraocular pressures (19,22). Glaucoma not confirmed. Will return for intraocular pressure check and tests.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09258",
"image_path": "slo_fundus_09258.jpg",
"filename": "data_09258.npz",
"report": "64 y.o. male with angle recession glaucoma in right eye due to past trauma; myopic right eye. Suspected glaucoma in the left eye based on appearance. No allergies. Asthma during exercise. Central corneal thickness: 582/573. Plan is to start timolol treatment for right eye; monitor asthma symptoms. History of blunt trauma in the right eye, resulting in retinal detachment. Early cataract identified in left eye. High myopia history in the right eye. No diabetic retinopathy observed.",
"age": 64.68,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "attending's assessment and plan: 64 y.o. male - angle recession glaucoma od, s/p blunt trauma od in DATE_TIME. on appears myopic od. PERSON, low 20s os. PERSON (sister has PERSON). medication intolerance: none. pt had asthma during exercise. central corneal thickness: 582/ 573 glaucoma suspect os based on on appearance. vf loss os in DATE_TIME 2/2 cryo scars goal PERSON, os around 20 plan: start timolol od bid - pt to monitor asthma symptoms - pseudophakia od 2005 s/p yag capsulotomy, early cataract os - hx of blunt trauma od, s/p sb for retinal detachment od in DATE_TIME and PERSON graft for exposed buckle s/p cryo os for retinal tears plan: per dr. PERSON \u00ff - epiretinal membrane ou - niddm, no retinopathy ou - hx of high myopia od - systemic / social: PERSON in DATE_TIME for iop and DATE_TIME. PERSON scribing for dr. PERSON. i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "64 y.o. male with angle recession glaucoma in right eye due to past trauma; myopic right eye. Suspected glaucoma in the left eye based on appearance. No allergies. Asthma during exercise. Central corneal thickness: 582/573. Plan is to start timolol treatment for right eye; monitor asthma symptoms. History of blunt trauma in the right eye, resulting in retinal detachment. Early cataract identified in left eye. High myopia history in the right eye. No diabetic retinopathy observed.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09261",
"image_path": "slo_fundus_09261.jpg",
"filename": "data_09261.npz",
"report": "69-year-old white, Hispanic male with no diagnosis of glaucoma. Instructed to sign into Partners Patient Gateway using his personal details.",
"age": 69.96,
"gender": "male",
"race": "white",
"ethnicity": "hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "a 69 y.o. white, hispanic male with no diagnosis of glaucoma. Partners Patient Gateway account, please sign in with your username and password. \u0007 You must log into your Partners Patient Gateway Account within 30 days or Activation code will expire. \u0007 Trouble logging in? Use Support Link found on the top right side of the Login Page. \u0007 Need help? Partners Patient Gateway Support Team makes every effort to respond to phone or email messages within 3 business day. To reach the Partners Patient Gateway Support Team, email patientgateway@partners.org or call 800-745-9683. Calls or messages are answered Monday to Friday, 8 a.m. to 5:00 p.m., EST - and will make every effort to contact you within 3 business days.",
"gpt4_summary": "69-year-old white, Hispanic male with no diagnosis of glaucoma. Instructed to sign into Partners Patient Gateway using his personal details.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09264",
"image_path": "slo_fundus_09264.jpg",
"filename": "data_09264.npz",
"report": "Patient's refractive status stable. Cataract OS, Epiretinal membrane OD and RF-negative RA all stable. Post phaco and retinal detachment repair in right eye also stable. Suspected glaucoma (due to increased cup/disc OS>OD), but intraocular pressure and humphrey visual fields normal, not worrisome for glaucoma. Left hemianopia reported, neurology appointment set.",
"age": 74.55,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "1. Refractive: No change -keep old glasses 2. Cataract OS: stable, doing well at home - monitor for now 3. Epiretinal membrane OD: moderate, stable, but acuity may also be limited by hx of old retinal detachment and repair -f/u with PERSON today 5. s/p phaco OD: Stable 6. s/p retinal detachment repair OD: retina attached - retinal detachment precautions -f/u with LY today 7. RF-negative RA: stable; no eye disease 8. Glaucoma suspect (incr cup/disc OS>OD): intraocular pressure OK again today, max pressure 18/21; humphrey visual fields are stable and not worrisome for glaucoma (but see below). The Optical coherence tomography is stable. -follow without meds for now -ok to stop testing for now as has been stable x many years DFE: 9/20 VF: 9/20 OCT: 9/20 Gonio: 2/13 Tmax: 18, 21 CCT: 596, 582 FHx: no 9) Left hemianopia: Pt says this developing right after her bypass surgery last year and has not changed. She has no other neurologic complaints. Has not been worked up in the past. -has appointment with neurology",
"gpt4_summary": "Patient's refractive status stable. Cataract OS, Epiretinal membrane OD and RF-negative RA all stable. Post phaco and retinal detachment repair in right eye also stable. Suspected glaucoma (due to increased cup/disc OS>OD), but intraocular pressure and humphrey visual fields normal, not worrisome for glaucoma. Left hemianopia reported, neurology appointment set.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09269",
"image_path": "slo_fundus_09269.jpg",
"filename": "data_09269.npz",
"report": "Patient with ALS has history of right lumbar radiculopathy with foot drop. Neuro-ophthalmic evaluation shows small anterior cortical opacities on both sides, but normal visual function. No glaucoma mentioned.",
"age": 45.25,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "formulation: this patent with als diagnosed in DATE_TIME is here for a follow up as per als research study. his symptoms started in DATE_TIME with right lower extremity weakness. he has history of right lumbar radiculopathy with right foot drop (surgery in DATE_TIME). his neuro-ophthalmic evaluation is overall unchanged, notable only for small anterior cortical opacities on on both sides. he has normal afferent and efferent visual function. no red desaturation. hvf, disc/fundus photos, cirrus sd-oct gcc, and macula oct were obtained DATE_TIME per study protocol. i will see him again per study protocol. this patent with als diagnosed in DATE_TIME is here for a follow up as per als research study. his symptoms started in DATE_TIME with right lower extremity weakness. he has history of right lumbar radiculopathy with right foot drop (surgery in DATE_TIME). his neuro-ophthalmic evaluation is overall unchanged, notable only for small anterior cortical opacities on on both sides. he has normal afferent and efferent visual function. we did not need to obtain a visual field or DATE_TIME. i will see him again per study protocol. impression: 1. als plan: 1. follow up per study schedule 1. follow up per study schedule this note was prepared with the assistance of PERSON, md, neuro-ophthalmology resident (pgy3). i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow. i have reviewed the resident/fellow's notes and made any necessary changes.",
"gpt4_summary": "Patient with ALS has history of right lumbar radiculopathy with foot drop. Neuro-ophthalmic evaluation shows small anterior cortical opacities on both sides, but normal visual function. No glaucoma mentioned.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09274",
"image_path": "slo_fundus_09274.jpg",
"filename": "data_09274.npz",
"report": "61 y.o male found to have mild cataract, controlled IOP, and glaucoma suspected due to increased C:D ratio and family history. New glasses prescribed.",
"age": 61.21,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "61 y.o. male 1. diabetes: no evidence of diabetic retinopathy. blood sugar, blood pressure, and cholesterol control encouraged. 2. mild cataract is present ou that is not visually significant. observation at this time was recommended. 3. glaucoma suspect based on inc c:d ratio fhx positive - father and mgm with glaucoma and ? pgf hvf full oct wnl dp stable iop controlled observe 4. refractive error: a prescription for new glasses was given to the patient DATE_TIME. 5. posterior vitreous detachment ou: no retinal holes, tears, or detachment on exam. retinal detachment precautions were reviewed with the patient. f/u 1 yr, mrx, iop, hvf, dilate, oct/dp",
"gpt4_summary": "61 y.o male found to have mild cataract, controlled IOP, and glaucoma suspected due to increased C:D ratio and family history. New glasses prescribed.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09275",
"image_path": "slo_fundus_09275.jpg",
"filename": "data_09275.npz",
"report": "The patient's left eye intraocular pressure is at the goal range. They are off glaucoma medications and have undergone laser peripheral iridotomy. Close monitoring will continue.",
"age": 63.47,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "single",
"note": "mmhg, left eye -iop at goal od and at goal os on DATE_TIME off glaucoma medications and s/p lpi ou x2. -continue close monitoring off glaucoma medications. -preservative-free artificial tears as needed. -rtc in DATE_TIME with iop check, hvf 24-2 size v, and disc photos ou, sooner prn. if hvf size v doesn't show deficits, disc photos, and iop stable, then we'll extend to DATE_TIME again with size v fields going forward. the information above was documented by Person as a scribe for PERSON on DATE_TIME. i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "The patient's left eye intraocular pressure is at the goal range. They are off glaucoma medications and have undergone laser peripheral iridotomy. Close monitoring will continue.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09276",
"image_path": "slo_fundus_09276.jpg",
"filename": "data_09276.npz",
"report": "70-year-old male patient has ocular hypertension, early cataracts, and recurrent erosion but currently doing well with conditions managed. No specific mention of glaucoma.",
"age": 70.1,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "70 yo male: 1. Refractive error: -new Rx for glasses given 2. Ocular hypertension OU: pressure ok today; has not had testing for some time - last seen here three years ago. VF: 1/16 HVF 7/23/2020: non-specific defects OCT: 1/16 OCT RNFL 7/23/2020: OD: normal/ OS: sup thinning Gonio: Tmax: 26, 27 CCT: 561, 553 FHx: yes - cont Timolol BID OU - add Dorzolamide BID OS - IOP check in 2-3 months 3. Early cataract OU: not visually significant, doing well -Monitor 4. Recurrent erosion: Doing well now without flare-ups Using artificial tears during the day (could not tolerate refresh PM- too thick) -follow",
"gpt4_summary": "70-year-old male patient has ocular hypertension, early cataracts, and recurrent erosion but currently doing well with conditions managed. No specific mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09277",
"image_path": "slo_fundus_09277.jpg",
"filename": "data_09277.npz",
"report": "The patient has open-angle glaucoma with high intraocular pressure and pain in both eyes. No known family history of glaucoma. Astigmatism detected, requiring cornea evaluation. Follow-up with specialists planned.",
"age": 40.18,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "? oag ou PERSON is +4 ou. iop is high- oct onh nfl is PERSON ou. reports pain ou. he will ask his family about family hx--none that he knows of. hvf wnl ou. superior kc ou see pentacam-astigmatism 2.7 d od 5.3 d os. no rubbing. needs cornea eval.. recommend conservative management. possible rigid cl fitting. PERSON ou nasal > temporal. recommend PERSON, sunglasses and using heat in the car on the floor. seasonal allergies ou no rubbing !!! allergy handout given. has an appointment with PERSON PERSON. f/u with glaucoma specialists in DATE_TIME. by signing my name below, i, PERSON, acting as a scribe, attest that this documentation has been prepared under the direction and in the presence of PERSON, md. DATE_TIME 9:07 am by signing my name below, i, PERSON, attest that this documentation has been prepared under my direction.",
"gpt4_summary": "The patient has open-angle glaucoma with high intraocular pressure and pain in both eyes. No known family history of glaucoma. Astigmatism detected, requiring cornea evaluation. Follow-up with specialists planned.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09279",
"image_path": "slo_fundus_09279.jpg",
"filename": "data_09279.npz",
"report": "The patient, a 95 y.o. female, has a long history of normal tension glaucoma in both eyes with fluctuating severity. She is on latanoprost treatment. Other issues - right nasolacrimal duct obstruction, DM without retinopathy, non-exudative age-related macular degeneration.",
"age": 95.37,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "first seen by dr. PERSON on DATE_TIME (previously followed by drs. PERSON, pasquale, rao, LOCATION, rhee, PERSON) glaucoma medication intolerances: none target iop: DATE_TIME, tmax: 20 / 18 central corneal thickness: 520 / 520 cornea hysteresis: 10.8 / 10.3 gonioscopy: d40f 1+ ou retinal nerve fiber layer, right eye: superior/inferior thinning retinal nerve fiber layer, left eye: borderline superior thinning visual fields, right eye: inferior > superior arcuate visual fields, left eye: inferior > superior arcuate family history: none steroids: none trauma: none asthma/copd: none other medical history and problems: dm, htn assessment/plan: 95 y.o. female # normal tension glaucoma, indeterminate stage, both eyes - long history at Institution, changes in drops from timolol to latanoprost to PERSON back to latanoprost then monitoring off medications, resumed latanoprost qhs ou DATE_TIME - mri brain DATE_TIME without mass lesion - vf's have fluctuated, severity does not quite correspond with exam/oct - iop acceptable ou, oct stable, vf fluctuating, may be worse but having increasing difficulty with testing reliability given age - continue on latanoprost qhs ou - return in DATE_TIME iop check # right nasolacrimal duct obstruction - symptomatic tearing and occasional epiphora - referral to oculoplastics # dm without retinopathy - blood sugar and blood pressure control, DATE_TIME dilated eye exam (last dfe DATE_TIME) # non-exudative age-related macular degeneration, both eyes - amsler grid # s/p cataract surgery with posterior chamber intraocular lens, both eyes - od DATE_TIME, os DATE_TIME - monitor PERSON scribing for dr. PERSON i attest that i was present while this encounter was recorded and agree that the information entered by my scribe and updated by me is complete and accurate. PERSON, md",
"gpt4_summary": "The patient, a 95 y.o. female, has a long history of normal tension glaucoma in both eyes with fluctuating severity. She is on latanoprost treatment. Other issues - right nasolacrimal duct obstruction, DM without retinopathy, non-exudative age-related macular degeneration.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09281",
"image_path": "slo_fundus_09281.jpg",
"filename": "data_09281.npz",
"report": "Non-glaucomatous cupping observed, no intraocular pressure elevation. Trace nuclear sclerosis and dry eyes present, yearly prescriptions planned. Glaucoma not mentioned.\n",
"age": 51.57,
"gender": "female",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "imp: non-glaucomatous cupping ou; normal hvf and DATE_TIME; no iop elevation trace nuclear sclerosis ou hx dry ou refr error plan: rx=m art tears prn yrly with hvf and oct",
"gpt4_summary": "Non-glaucomatous cupping observed, no intraocular pressure elevation. Trace nuclear sclerosis and dry eyes present, yearly prescriptions planned. Glaucoma not mentioned.\n",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09283",
"image_path": "slo_fundus_09283.jpg",
"filename": "data_09283.npz",
"report": "52 y.o. male suspected of glaucoma due to cup-to-disc ratio. No signs of thinning in retinal nerve fiber layer. No treatment initiated but will continue to monitor. Also has minor cataracts, but not visually significant.",
"age": 52.67,
"gender": "male",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "first seen by on DATE_TIME glaucoma medication intolerances: none target iop: DATE_TIME, tmax: 17 / 18 central corneal thickness: 565 / 536 gonioscopy: c35f 2+ ou retinal nerve fiber layer, right eye: no thinning retinal nerve fiber layer, left eye: no thinning visual fields, right eye: full visual fields, left eye: full family history: none steroids: none trauma: none asthma/copd: none other medical history and problems: cad s/p pci, on LOCATION, htn, hld, osa assessment/plan: 52 y.o. male government contract agent # glaucoma suspect due to cup to disc ratio, both eyes - large nerve head, suspect physiologic cupping - iop acceptable ou, testing reassuring - continue to monitor without initiating treatment - return in DATE_TIME for iop check, dilate # eyelash buried under conjunctiva, left eye - small snip incision made with vannas scissors, lash removed with jewelers at slit lamp DATE_TIME - moxifloxacin qid os x DATE_TIME # cataract, both eyes - mild, not visually significant, monitor PERSON, md",
"gpt4_summary": "52 y.o. male suspected of glaucoma due to cup-to-disc ratio. No signs of thinning in retinal nerve fiber layer. No treatment initiated but will continue to monitor. Also has minor cataracts, but not visually significant.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09285",
"image_path": "slo_fundus_09285.jpg",
"filename": "data_09285.npz",
"report": "The female patient has primary open-angle glaucoma (POAG) with a higher cup-to-disc ratio in the right eye. Her intraocular pressure (IOP) is stable. She has a mild, non-visually significant cataract in the right eye. Underwent phacoemulsification and posterior chamber intraocular lens. She's doing well post-operation.",
"age": 70.87,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "DATE_TIME. female 1. poag(s) based on inc c:d ratio, od>os has been followed by optom with regular hvfs in the past fhx negative tmax unknown hvf full ou oct wnl ou dp stable iop controlled ou observe 2. s/p phaco/pciol os DATE_TIME, aimed myopic s/p yag cap os DATE_TIME doing well DATE_TIME/o erm, s/p ppv/mp DATE_TIME os dr. PERSON doing well 4. mild cataract is present od that is not visually significant. observation at this time was recommended. 5. refractive error: a prescription for new glasses was given to the patient DATE_TIME. DATE_TIME, mrx, iop, hvf, dilate, oct and dp PERSON scribing for dr. PERSON at DATE_TIME on DATE_TIME. i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "The female patient has primary open-angle glaucoma (POAG) with a higher cup-to-disc ratio in the right eye. Her intraocular pressure (IOP) is stable. She has a mild, non-visually significant cataract in the right eye. Underwent phacoemulsification and posterior chamber intraocular lens. She's doing well post-operation.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09286",
"image_path": "slo_fundus_09286.jpg",
"filename": "data_09286.npz",
"report": "Patient is a glaucoma suspect with no family history. IOP is 12/12 consistently. OCT reveals thin rim in right eye, bordering issues in left. Inferior defect is noted.",
"age": 77.39,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "DATE_TIME URLle presents for glaucoma tests 1. glaucoma suspect -black, DATE_TIME -no family history -iop 12/12 (DATE_TIME) 12/12 (DATE_TIME) 12/12 (DATE_TIME, with thin rim oct: right eye reliability was good. left eye reliability was good. findings right eye normal left eye superior was borderline. the other was normal. hvf: hvf mean deviation (os) - left eye NRP hvf mean deviation (od) - right eye +1.56 right eye reliability/fixation was poor mean deviation was calculated to be: PERSON db. interpretation of the testing revealed: non-specific defects. left eye reliability/fixation was poor. mean deviation was calculated to be: PERSON db. interpretation of the testing revealed: inferior defect refer to glaucoma",
"gpt4_summary": "Patient is a glaucoma suspect with no family history. IOP is 12/12 consistently. OCT reveals thin rim in right eye, bordering issues in left. Inferior defect is noted.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09288",
"image_path": "slo_fundus_09288.jpg",
"filename": "data_09288.npz",
"report": "Patient is a low-risk glaucoma suspect with no known family history or high IOP. Both RNFL OCT and HVF are normal. Glaucoma was discussed, with emphasis on treatment adherence. Cataract is also being monitored.",
"age": 50.88,
"gender": "female",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "# glaucoma suspect, low risk, ou: - no known family hx of glaucoma - no known h/o high iop, gonio open - rnfl oct and hvf wnl ou DATE_TIME - diagnosis of glaucoma/glaucoma suspect discussed with patient - review of natural history and management options discussed. importance of lifelong follow up and adherence to treatments discussed in order to lower risk of permanent vision loss/blindness from glaucoma. all questions answered. - recommend monitoring # cataract ou nvs - not vis sig monitor f/u DATE_TIME hvf/oct/dfe, sooner prn\u00ff \u00ff",
"gpt4_summary": "Patient is a low-risk glaucoma suspect with no known family history or high IOP. Both RNFL OCT and HVF are normal. Glaucoma was discussed, with emphasis on treatment adherence. Cataract is also being monitored.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09289",
"image_path": "slo_fundus_09289.jpg",
"filename": "data_09289.npz",
"report": "Patient had an intraocular pressure check, humphrey visual field, and optical coherence tomography. Relatives advised to be examined for glaucoma.",
"age": 62.47,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "reviewed return to clinic DATE_TIME for intraocular pressure check, humphrey visual field, optical coherence tomography and dilation advised that siblings and first degree relatives be examined for glaucoma PERSON scribing for dr. PERSON (DATE_TIME, 6:18 am) i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "Patient had an intraocular pressure check, humphrey visual field, and optical coherence tomography. Relatives advised to be examined for glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09290",
"image_path": "slo_fundus_09290.jpg",
"filename": "data_09290.npz",
"report": "Debra L Sybertz is a low risk open angle glaucoma suspect with narrow, occludable angles. After laser peripheral iridotomy (LPI), her intraocular pressure (IOP) is okay without medication. She also has senile cataract and dermatochalasis.",
"age": 63.87,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "debra l sybertz is a DATE_TIME DATE_TIME patient previously a patient of first seen by dr. LOCATION on DATE_TIME # open angle glaucoma suspect low risk od, low risk os s/PERSON narrow angles - occludable ou on gonio DATE_TIME - s/p lpi ou with open angle and iop ok on no meds risk factors: central corneal thickness: / gonioscopy: tmax: ( ) / ( ) target iop: / refractive error wrx: PERSON. -0.25. 158 / os +1.50. -0.50. 115 glaucoma procedures/lasers: s/PERSON ou other eye procedures/lasers: none glaucoma medication issues: none negative sulfa allergy testing: baseline DATE_TIME (DATE_TIME) oct rnfl: full ou (DATE_TIME) hvf 24-2 ou: within normal limits ou # combined senile cataract - may becoming visually significant - monitor for now # dermatochalasis ul ou - pt noting vis sig at DATE_TIME, following up with evaluation at pro optical plan DATE_TIME: iop tonometry tonometry (applanation, DATE_TIME) right left pressure 14 14 tonometry #2 (app by LOCATION dilation, DATE_TIME) right left pressure DATE_TIME , acceptable od, acceptable os pt is new to me, here for dfe, hvf 24-2, and oct. . imaging full and within normal limits. dfe normal. continue to monitor off meds last dilated exam: DATE_TIME DATE_TIME rnfl: DATE_TIME last visual field: DATE_TIME baseline disc photos: DATE_TIME return to glaucoma clinic in DATE_TIME with dfe, optical coherence tomography rnfl, and humphrey visual field 24-2 PERSON acting as scribe for",
"gpt4_summary": "Debra L Sybertz is a low risk open angle glaucoma suspect with narrow, occludable angles. After laser peripheral iridotomy (LPI), her intraocular pressure (IOP) is okay without medication. She also has senile cataract and dermatochalasis.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09294",
"image_path": "slo_fundus_09294.jpg",
"filename": "data_09294.npz",
"report": "The patient has impaired vision due to cortical dysfunction. They have a non-modifiable risk factor for cardiovascular diseases due to migraine with aura. No changes in current medication are required. No mention of glaucoma.",
"age": 67.55,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "the time of the visual aura, however, the patient should not drive, as vision is truly impaired due to dysfunction of the cortical visual areas. we also discussed that the presence of migraine with aura is a non-modifiable risk factor for cardiovascular and cerebrovascular disease. i do not think that his current treatment regiment of apixaban, atorvastatin and bp meds needs to be adjusted. we discussed this diagnostic impression and plan in detail. we have not scheduled further follow-up but i am happy to see the patient again if the need arises. thank you for allowing me to participate in the care of your patient. ???? ??please do not hesitate to call with questions. ? sincerely, ? PERSON, LOCATION neuro-ophthalmology, headache unit, and inflammatory neuro-ophthalmology/skull base disorders clinic. division of comprehensive neurology, Institution neuro-ophthalmology, Institution ? note: greater than half of this DATE_TIME visit was spent counseling the patient on the medical condition or coordinating care. this time excludes any listed procedures.",
"gpt4_summary": "The patient has impaired vision due to cortical dysfunction. They have a non-modifiable risk factor for cardiovascular diseases due to migraine with aura. No changes in current medication are required. No mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09295",
"image_path": "slo_fundus_09295.jpg",
"filename": "data_09295.npz",
"report": "Patient stable with giant cell arteritis. Visual acuity, color vision, visual field changes, fundus exam and ganglion cell thickness are normal. No signs of glaucoma.\n",
"age": 85.11,
"gender": "male",
"race": "white",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "married or partnered",
"note": "formulation: this patient returns for follow up of gca. my exam revealed stable visual acuity and color vision. his automated (humphrey) visual field showed non-specific changes on the right (stable), and inferior nasal loss on the left side (stable/improved). his fundus exam revealed normal disc on the right side. on the left, there was no disc pallor, however, there was excavation of the superior margin of the disc with a vessel crossing through the superior rim. overall, the appearance of the left optic disc was stable. his oct showed normal ganglion cell thickness results. overall, he is stable visually, and my exam shows no change. he is currently on 10 mg prednisone DATE_TIME and his esr DATE_TIME is 9. his rheumatologist is managing his prednisone taper and i will defer to him in this regard. i agree with considering tocilizumab per his rheumatologist. i generally treat with prednisone for DATE_TIME, depending upon the details of each specific case. the goal is to use the lowest dose of corticosteroid possible to maintain quiescence of the disease. given that he had a very high esr initially (>100), this serology is useful to monitor to assess disease activity. his esr DATE_TIME of 9, is reassuring. impression: 1. giant cell arteritis recommendations: 1. continue the prednisone per rheumatology; consider tocilizumab 2. follow up with neuro-ophthalmology clinic in DATE_TIME. follow-up neuro-ophthalmic examination with PERSON as scheduled PERSON, PERSON fellow",
"gpt4_summary": "Patient stable with giant cell arteritis. Visual acuity, color vision, visual field changes, fundus exam and ganglion cell thickness are normal. No signs of glaucoma.\n",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09304",
"image_path": "slo_fundus_09304.jpg",
"filename": "data_09304.npz",
"report": "Patient has cataracts in both eyes but is not symptomatic. Disc asymmetry noted, but normal hvf and oct. No mention of glaucoma. Plan: 6-month check-up.",
"age": 73.87,
"gender": "male",
"race": "white",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "single",
"note": "imp: cataracts ou, but not symptomatic and corrects to 20/20 disc asymmetry, but thick cct and normal hvf and oct refr error plan: 6 mo--refract and dilated exam",
"gpt4_summary": "Patient has cataracts in both eyes but is not symptomatic. Disc asymmetry noted, but normal hvf and oct. No mention of glaucoma. Plan: 6-month check-up.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09308",
"image_path": "slo_fundus_09308.jpg",
"filename": "data_09308.npz",
"report": "The patient is a 60-year-old woman with a complicated cataract in her left eye, idiopathic NRP in both eyes, and cataract in her right eye. She also has refractive errors and is a glaucoma suspect. She has not been using her glaucoma medication consistently.\n",
"age": 63.1,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "60 yo woman presents with: 1. complicated cataract os -- requiring synechiolysis, malyugan ring, trypan blue staining DATE_TIME. procedure complicated by pc rupture and retained nuclear material (approx 60-75% of the nucleus). s/p pars plana lensectomy DATE_TIME with tiny wisp of retained cortex in inferior vitreous base - quiet off topical steroids 2. idiopathic NRP, ou: - s/p diagnositic ppv DATE_TIME: results from vitrectomy specimen: viral and toxoplasmosis pcrs are negative, no growth on cultures, cytology shows histiocytes, small lymphocytes and occasional giant cells, il-6 is less than 3.9 and LOCATION is 2.8, igh gene rearrangement is negative?. - serologies DATE_TIME: increased alt (32) and ast (42); repeated DATE_TIME lfts normal. other serologies were negative, including ana, lyme, rpr/fta-abs, ace/lysozyme, LOCATION, PERSON. normal esr. s/p cellcept therapy, failed due to toxicity - labs DATE_TIME: quantiferon gold: positive. she had a ppd placed DATE_TIME which as negative (0mm). originally from antigua, has had prior negative ppds. 3. s/p ppv os for persistent tuft of vitreous over the fovea os?? - good result, improvement in visual acuity - no breaks or tears seen previously \u00ff 4. cataract, od: - nvs; monitor \u00ff 5. refractive error: - mr=rx DATE_TIME. glaucoma suspect -- negative family history -- declines pachy and gonio -- improved with cosopt bid ou, but patient has had poor compliance ('i do not used it consistently because it stings for DATE_TIME) -- DATE_TIME iop 21/23 -- continue cosopt bid ou, brimonidine bid ou; will increase brimonidine to tid ou rtc 3-4 months with oct rnfl on arrival",
"gpt4_summary": "The patient is a 60-year-old woman with a complicated cataract in her left eye, idiopathic NRP in both eyes, and cataract in her right eye. She also has refractive errors and is a glaucoma suspect. She has not been using her glaucoma medication consistently.\n",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09311",
"image_path": "slo_fundus_09311.jpg",
"filename": "data_09311.npz",
"report": "74 yo retired surgeon with history of colonic polyps has normal tension glaucoma. On Travatan Z, with good compliance. Will be referred for further glaucoma management. Also has cataracts.",
"age": 74.8,
"gender": "male",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "74 yo retired orthopedic surgeon and PERSON father, with history of colonic polyps new patient DATE_TIME 1. normal tension glaucoma (c/d, hvf) has received care in LOCATION: tmax 20 ou per patient. no fhx glaucoma started travatan z ou qhs since DATE_TIME (LOCATION), was told iop decr'd to 15 ou last hvf DATE_TIME in LOCATION DATE_TIME DATE_TIME: gonio: cbb 360' ou cct DATE_TIME (ave) hvf DATE_TIME: od ins. os central depression >> vf loss od (apparently new) correlates with onh. ta 12 ou on travatan z with good compliance. will refer to glaucoma for further management 2. cataract ou >> updated mrx DATE_TIME 3. guttae ou",
"gpt4_summary": "74 yo retired surgeon with history of colonic polyps has normal tension glaucoma. On Travatan Z, with good compliance. Will be referred for further glaucoma management. Also has cataracts.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09312",
"image_path": "slo_fundus_09312.jpg",
"filename": "data_09312.npz",
"report": "78 y.o. white, non-hispanic female diagnosed with glaucoma.",
"age": 78.23,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "a 78 y.o. white, non-hispanic female was evaluated and diagnosed with glaucoma.",
"gpt4_summary": "78 y.o. white, non-hispanic female diagnosed with glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09313",
"image_path": "slo_fundus_09313.jpg",
"filename": "data_09313.npz",
"report": "Patient shows optic atrophy (OD > OS) and increased cup to disc ratios. Glaucoma a possibility but not a leading diagnosis. Ruling out compressive lesion, nutritional deficiencies, and syphilis. Recommends MRI test.",
"age": 36.82,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "od > os. her history does not reveal any clear etiology to explain this finding. the decline in visual acuity along with the dyschromatopsia favor a non glaucomatous etiology. in this case, it is indicated to rule out a compressive lesion as well as other causes of reversible optic neuropathies such as nutritional (folate, b12, copper) and infectious (syphilis); i asked PERSON to provide me with her previous records to help evaluate if there has been any progression. if the initial work up comes back completely negative, we will descuss the relevance of obtaining genetic testing for dominant optic atrophy. although glaucoma remains a possibility, it remains a diagnosis of exlclusion in this situation. impression: 1. optic atrophy od > os -rule out compressive lesion -rule out nutritional (folate, b12) -rule out other reversible cause of optic neuropathy, i.e syphilis. -doa to consider. 2. increased cup to disc ratios ou -family history os glaucoma -ntg is a diagnosis of exclusion. 3. ?refractive amblyopia os recommendations: 1. mri brain and orbits c+ c- 2. LOCATION, LOCATION, LOCATION, mma, PERSON, folate 3. obtain records from LOCATION 4. follow up in DATE_TIME, before if needed. it is a pleasure to participate in the care of this patient. please do not hesitate to call with questions. ? sincerely, ? PERSON, PERSON spent DATE_TIME with this patient, more than 50% of which was face to face with the patient.",
"gpt4_summary": "Patient shows optic atrophy (OD > OS) and increased cup to disc ratios. Glaucoma a possibility but not a leading diagnosis. Ruling out compressive lesion, nutritional deficiencies, and syphilis. Recommends MRI test.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09314",
"image_path": "slo_fundus_09314.jpg",
"filename": "data_09314.npz",
"report": "Patient has hyperopia and astigmatism. Mild symptoms reported, no ocular signs of optic neuritis or MS. Family history of glaucoma, but tests normal so far. Glaucoma testing to be repeated. MRI planned.",
"age": 36.41,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "imp: ref error- hyperopia with astigmatism ou -son putting glasses at high risk of breaking, seeking ctl referral mgd/blepharitis incr c:d ou- PERSON, but + fhx glaucoma (grandmother) PERSON full, oct normal DATE_TIME -cct 479/484 urgent complaint: episodes of feeling eyes not tracking well, episode of room spinning, mild systemic symptoms (temp sensitivity) -underwent outpatient blood workup, negative -outside practitioner mentioned possibility of ms: DATE_TIME normal acuity, colors, motility, no pain with eye movement, no nerve edema, no relative afferent pupillary defect. overall no ocular signs of optic neuritis or ms. patient to get mri in DATE_TIME. -discussed overall normal eye exam, recommend continued workup with his pcp plan: wc, ats follow up with pcp as planned repeat glaucoma testing DATE_TIME ctl referral per patient preference weinert, pgy4 i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow. i have reviewed the resident/fellow's notes and made any necessary changes.",
"gpt4_summary": "Patient has hyperopia and astigmatism. Mild symptoms reported, no ocular signs of optic neuritis or MS. Family history of glaucoma, but tests normal so far. Glaucoma testing to be repeated. MRI planned.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09319",
"image_path": "slo_fundus_09319.jpg",
"filename": "data_09319.npz",
"report": "33-year-old female with suspected glaucoma started on timolol. She has a family history of glaucoma. Currently, no signs of glaucoma are found with normal eye exams and testing. She will be temporarily taken off timolol.",
"age": 33.25,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "33 y.o.f woman w/pmh chronic ha, narcolepsy w/o cataplexy (on LOCATION, stimulants), depression, s/p sinus surgery, follows with PERSON in LOCATION, started timolol ~ DATE_TIME bid ou for ?glaucoma suspect / thinning on oct (records not available DATE_TIME for review). glaucoma suspect, ou, low risk unknown tmax cct 560's ou gonio wide open ou tcurrent on timolol 16 ou + f/h glaucoma mgf (was on drops, no surgery) and brother (hx rop, angle closure) no personal hx eye surgery/laser/injury denies prev symptoms of pds steroid cream for eczema very rarely for yrs (not on face) reviewed findings -- all reassuring, no signs of glaucoma at this time with full hvf, normal oct and normal clinical exam without signs of secondary causes of intermittent ohtn d/w patient - safe iop for her is likely <22 at this time # mild myopia with astigmatism ou plan - trial off of timolol return DATE_TIME iop check patient will bring records for review at that time",
"gpt4_summary": "33-year-old female with suspected glaucoma started on timolol. She has a family history of glaucoma. Currently, no signs of glaucoma are found with normal eye exams and testing. She will be temporarily taken off timolol.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09320",
"image_path": "slo_fundus_09320.jpg",
"filename": "data_09320.npz",
"report": "The patient has glaucoma, high myopia, vision complications, and allergies to eye drops. The patient's parents also had glaucoma. Eye pressure is typically in single digits. Optic disc exam shows loss. The treatment plan includes trabeculectomy or xen implant.",
"age": 67.6,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "# poag ou dx in DATE_TIME currently followed by PERSON in LOCATION/PERSON DATE_TIME for high myopia + flonase in the past, joint steroid injections no trauma treated with drops only since dx multiple allergy to eyedrops and preservatives arrives on LOCATION nightly and timolol bid ou parents with glaucoma, one sister ( no vision loss per patient) pp ou , s/p istent ou ttarget: / , tmax unknown, per patient iop usually in single digits cct: 497 / 507 gonioscopy: open to cbb ou rnfl oct inf thinning ou vf dense sup defects ou plan: high myope with anomalous nerves dense superior vf defects ou with matching inf thinning on oct optic disc exam appears to have loss of PERSON per patient vf have been worsening (only one prior available for review DATE_TIME) and subjectively worsening vision discussed with patient the difficulty with diagnosis and treatment of her condition there is some evidence of single digit iops may be beneficial in patients similar to her also cannot tolerate drops i think it is reasonable to proceed with trabeculectomy or xen implant ou -- as long as she understands the higher risk of symptomatic hypotony especially as we are aiming for single digit pressures of note she is not on bp medications diagnosis of glaucoma/glaucoma suspect discussed with patient - review of natural history and management options discussed. importance of lifelong follow up and adherence to treatments discussed in order to lower risk of permanent vision loss/blindness from glaucoma. all questions answered. i spent DATE_TIME with the patient, more than half of which was spent on counseling and coordination of care for this patient's glaucoma",
"gpt4_summary": "The patient has glaucoma, high myopia, vision complications, and allergies to eye drops. The patient's parents also had glaucoma. Eye pressure is typically in single digits. Optic disc exam shows loss. The treatment plan includes trabeculectomy or xen implant.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09321",
"image_path": "slo_fundus_09321.jpg",
"filename": "data_09321.npz",
"report": "Patient has glaucoma and cataracts. Current treatment isn't controlling intraocular pressure (IOP) effectively. Medication changing from Trusopt to Cosopt. Counseling given about treatment adherence.",
"age": 79.58,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "LOCATION; she has hyperlipidemia. attending's plan: -goal intraocular pressure less than or equal to 12 mmhg, right eye. -goal intraocular pressure less than or equal to 12 mmhg, left eye. -iop above goal od and above goal os on DATE_TIME on trusopt 2% bid ou. -stop trusopt 2% bid ou. -start cosopt bid ou. -start LOCATION qhs ou. -instructions written/typed/printed out for patient (see table/details under patient instructions). -emphasized adherence to medication regimen. -preservative-free artificial tears as needed. -retinal detachment precautions were reviewed with the patient. -rtc in DATE_TIME with iop check, arx, bat, optical biometry, dilation, and disc photos ou, sooner prn. if iop above goal at next visit, strongly consider phaco/xen gel stent vs. phaco/trab mmc os. i spent DATE_TIME with the patient and her husband, more than half of which was spent on counseling and coordination of care for this patient's glaucoma and cataracts. the information above was documented by PERSON as a scribe for PERSON on DATE_TIME. i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow (PERSON, md). i have reviewed the resident/fellow's notes and made any necessary changes.",
"gpt4_summary": "Patient has glaucoma and cataracts. Current treatment isn't controlling intraocular pressure (IOP) effectively. Medication changing from Trusopt to Cosopt. Counseling given about treatment adherence.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09328",
"image_path": "slo_fundus_09328.jpg",
"filename": "data_09328.npz",
"report": "Patient might have narrow angles and was recommended to have a gonioscopy. Family history of glaucoma, with mother and maternal grandmother both having treatments. Currently uses glasses and has no past eye surgeries or allergies.",
"age": 47.87,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "patient was told by optometrist that she might have narrow angles. she was recommended to see ophthalmologist and have gonioscopy. pt saw PERSON PERSON DATE_TIME, and PERSON referred patient here. mother with history of lpi's ou but DATE_TIME older than when pt had it. \u00ff 1. occludable narrow angles ou (plateau iris component) - started glasses when mostly for reading, started glasses around 39 yo - mild hyperope or latent hyperope; when saw dr. papaliodis, rx was LOCATION 16 ou meei as of DATE_TIME - no eye drop or medical allergies - no past lasers and surgeries for eyes - fh glaucoma - mother with lpis ou - had lasers at 65 yo (mother also has dm); maternal grandmother (dm, 'very bad' glaucoma, also had surgery for this) - no h/o past ocular trauma - uses NRP steroids prn for hematology condition (itp) - plateau iris configuration ou per ubm DATE_TIME - s/p lpi od DATE_TIME (with intermittent light reflex, pt re-assured it was expected) - s/p lpi os DATE_TIME - stable with ch 9.5 od (DATE_TIME), borderline od, unable os (?) a. re-iterated possibility of aacg; also need for cacg screening life-long b. recheck DATE_TIME dilated hvf and DATE_TIME. presbyopia - uses glasses prn \u00ff",
"gpt4_summary": "Patient might have narrow angles and was recommended to have a gonioscopy. Family history of glaucoma, with mother and maternal grandmother both having treatments. Currently uses glasses and has no past eye surgeries or allergies.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09329",
"image_path": "slo_fundus_09329.jpg",
"filename": "data_09329.npz",
"report": "The patient has retinal detachment in both eyes and is seeing a glaucoma specialist. The goal for intraocular pressure is less than or equal to 17 mmHg (right eye) & 15 mmHg (left eye). Adherence to the medication regimen was emphasized, and blood sugar and blood pressure control were encouraged.",
"age": 71.04,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "detachment, both eyes -retinal detachment precautions were reviewed with the patient. 7. social/systemic issues: patient was seeing a glaucoma specialist in LOCATION, LOCATION has returned back to residing in PERSON as of DATE_TIME. of note, she comes from a family of 12 children. she will be visiting her family from DATE_TIME to visit her children. attending's plan: -goal intraocular pressure less than or equal to 17 mmhg, right eye. -goal intraocular pressure less than or equal to 15 mmhg, left eye. -iop at goal od and at goal os on DATE_TIME on intermittent PERSON, brimonidine tid ou, and rhopressa qhs ou. -continue PERSON qhs ou consistently => sample given on DATE_TIME. -continue brimonidine tid ou. -continue rhopressa qhs ou => sample given on DATE_TIME, DATE_TIME, and DATE_TIME. -instructions written/typed/printed out for patient (see table/details under patient instructions) previously. -emphasized adherence to medication regimen. -continue pazeo bid ou prn itching -emphasized adherence to medication regimen. -retinal detachment precautions were reviewed with the patient. -encouraged tight blood glucose, blood pressure and blood cholesterol control. -preservative-free artificial tears as needed. -mrx given at patient's request on DATE_TIME. -mrx given at patient's request on DATE_TIME. -rtc DATE_TIME with iop check and disc photos ou, sooner prn. if iop above goal in the future, consider phaco/ecp/kdb versus phaco/ecp/istent os first. i saw and evaluated this patient and discussed the case as appropriate with the medical student (PERSON). i have reviewed the medical student's notes and made any necessary changes.",
"gpt4_summary": "The patient has retinal detachment in both eyes and is seeing a glaucoma specialist. The goal for intraocular pressure is less than or equal to 17 mmHg (right eye) & 15 mmHg (left eye). Adherence to the medication regimen was emphasized, and blood sugar and blood pressure control were encouraged.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09330",
"image_path": "slo_fundus_09330.jpg",
"filename": "data_09330.npz",
"report": "The clinical note doesn't provide explicit information on the presence of glaucoma. It mentions a future visual field test and reports on conditions including asthma, bronchitis, hypertension, hepatitis B, stress incontinence, and cellulitis.",
"age": 64.51,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "nerve - ou - both eyes - oct, retina - ou - both eyes - future labs/procedures complete by expires humphrey visual field - ou - both eyes as directed DATE_TIME - both eyes - as directed DATE_TIME condition list as of DATE_TIME asthma bronchitis hypertension history of hepatitis b female stress incontinence cellulitis of extremity results summary immunizations administered on date of encounter - DATE_TIME none patient gateway activation information your account is ready to use. activate your account using following steps: 1. visit URL. 2. click 'enroll now' and create your user account.",
"gpt4_summary": "The clinical note doesn't provide explicit information on the presence of glaucoma. It mentions a future visual field test and reports on conditions including asthma, bronchitis, hypertension, hepatitis B, stress incontinence, and cellulitis.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09332",
"image_path": "slo_fundus_09332.jpg",
"filename": "data_09332.npz",
"report": "The patient has persistently elevated intraocular pressure (IOP) indicative of glaucoma, hence the recommendation for surgery. However, due to a pre-planned trip, surgery might be rescheduled. Also, the right eye pain could be due to dryness. Re-commencing taping recommended.",
"age": 49.19,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "he wouldn't feel comfortable managing her anymore). -long discussion with patient on DATE_TIME: given persistently elevated iop od on close to mtmtx (except for po cais and vyzulta), i do recommend proceeding with in bgi od. however, patient has LOCATION trip planned in DATE_TIME, which she can't reschedule. (1) most likely i will see her before her trip to LOCATION for hvf 10-2 od and iop check as well as dilation ou or (2) if there's a cancellation for surgery on DATE_TIME, we will proceed on that date. we proceeded with in bgi in sulcus od on DATE_TIME. -long discussion with patient on DATE_TIME: i will discuss situation with PERSON (i provided my personal cell phone number to be given to dr. PERSON). once we discuss the situation, i may do telemedicine with her. i think that maybe her right eye pain symptoms are related to dryness, and i recommended re-commencing taping at DATE_TIME with e-mycin ointment as well as frequent lubrication. -rtc in DATE_TIME with iop check and disc photos ou, sooner prn. i spent DATE_TIME with the patient, more than half of which was spent on counseling and coordination of care for this patient's glaucoma.",
"gpt4_summary": "The patient has persistently elevated intraocular pressure (IOP) indicative of glaucoma, hence the recommendation for surgery. However, due to a pre-planned trip, surgery might be rescheduled. Also, the right eye pain could be due to dryness. Re-commencing taping recommended.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09334",
"image_path": "slo_fundus_09334.jpg",
"filename": "data_09334.npz",
"report": "Patient to undergo glaucoma surgery in left eye. Recommended for virus testing pre-surgery. Pending arrangement for COVID testing.",
"age": 84.38,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "based on your visit with dr. PERSON on DATE_TIME, she is planning to do glaucoma surgery in the left eye. to keep the operating room a safe place, dr. PERSON is recommending you to be tested for the DATE_TIME virus within DATE_TIME before your surgery. her secretary will arrange for covid testing. her secretary's name is PERSON, and she will call you to schedule your procedure. if you don't hear from her in DATE_TIME, please call her at PHONE_NUMBER. if you have questions about medications not related to your eyes, please call your primary care physician.",
"gpt4_summary": "Patient to undergo glaucoma surgery in left eye. Recommended for virus testing pre-surgery. Pending arrangement for COVID testing.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09339",
"image_path": "slo_fundus_09339.jpg",
"filename": "data_09339.npz",
"report": "54 y.o. male with gout history, recurrent anterior uveitis & glaucoma suspicion due to asymmetric cup-to-disc ratio. No active ocular inflammation, lumbar x-ray suggests possible ankylosing spondylitis. Stable intraocular pressure.",
"age": 54.63,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "54 y.o. male with h/o gout, r v1 zoster # recurrent anterior uveitis od patient had serologies by pcp including PERSON (neg), lyme serology (equivocal -- positive igm criteria and negative igg); ace (negative); quantiferon gold (neg). synchronously with his iritis he developed a 'pulmonary inflammation' that has been treated by his pulmonologist with systemic prednisone patient had chest ct scan that was negative patient had right v1 shingles DATE_TIME -no evidence of active ocular inflammation -unable to confirm whether recent episodes represent true recurrences; pt starts using pred forte and symptoms resolve within DATE_TIME. -reports he has not had a recurrence since having shingles. -DATE_TIME: reports he had a recent lumbar xray showing possible ankylosing spondylitis. following with rheumatologist. >observe # glaucoma suspect, cdr asymmetry -tmax 24/23 -pachy: 536/542 -gonio: open ou -oct DATE_TIME: od inferiorly thinning; os normal -hvf DATE_TIME: full ou >monitor off drops # steroid associated glaucoma -iop stable off istalol # right v1 hzv DATE_TIME -resolved lagopthalmos od f/u 6 mos: iop, oct rnfl",
"gpt4_summary": "54 y.o. male with gout history, recurrent anterior uveitis & glaucoma suspicion due to asymmetric cup-to-disc ratio. No active ocular inflammation, lumbar x-ray suggests possible ankylosing spondylitis. Stable intraocular pressure.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09343",
"image_path": "slo_fundus_09343.jpg",
"filename": "data_09343.npz",
"report": "70 y.o. male has normal tension glaucoma; mild in right eye, severe (paracentral) in left. Dorzolamide allergy. Retinal nerve fibers show no thinning in right eye, inferior thinning in left. Family history of glaucoma.",
"age": 70.79,
"gender": "male",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "first seen by dr. PERSON on DATE_TIME glaucoma medication intolerances: dorzolamide (allergy) target iop: DATE_TIME, tmax: high teens ou central corneal thickness: 514 / 513 gonioscopy: PERSON 2+ ou retinal nerve fiber layer, right eye: no focal thinning retinal nerve fiber layer, left eye: inferior thinning visual fields, right eye: full visual fields, left eye: dense superior arcuate family history: brother and several other family members steroids: none trauma: none asthma/copd: none other medical history and problems: graves disease s/p iodine ablation and subsequent hypothyroidism, ckd, gout assessment/plan: 70 y.o. male retired computer science professor # normal tension glaucoma, mild right eye, severe (paracentral) left eye - outside vf appears stable for DATE_TIME, oct os may be slightly worse vs image capture fluctuation - iop acceptable ou - vf and oct roughly stable, some slight fluctuation in 10-2 os but not definitive for change - continue latanoprost qhs ou, PERSON - discussed that options for next steps os include vyzulta, rhopressa/rocklatan, or timolol; will hold for now as long as iop reasonable and testing stable - return in DATE_TIME for iop check, vf (24-2 od and a 24-2 and 10-2 os), dilate, DATE_TIME PERSON, left eye - mild, not visually significant, monitor # cataract, both eyes - mild, not visually significant, monitor PERSON scribing for dr. PERSON i attest that i was present while this encounter was recorded and agree that the information entered by my scribe and updated by me is complete and accurate. PERSON, md",
"gpt4_summary": "70 y.o. male has normal tension glaucoma; mild in right eye, severe (paracentral) in left. Dorzolamide allergy. Retinal nerve fibers show no thinning in right eye, inferior thinning in left. Family history of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09347",
"image_path": "slo_fundus_09347.jpg",
"filename": "data_09347.npz",
"report": "Patient had a crusting rash on left forehead that was suspiciously like shingles but tested negative. A slow decline in disease was noted, the patient had high intraocular pressure previously. Has asthma but tolerates timolol well. Glaucoma and cornea follow-up arranged.",
"age": 77.5,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "other",
"maritalstatus": "married or partnered",
"note": "DATE_TIME dr. PERSON # pciol ou: - per patient performed in DATE_TIME by dr. PERSON of independence eye associates in dartmouth, ma # query vzv LOCATION / endotheliitis os: patient endorses having had a very itchy crusting rash over the left forehead that extended down to the left brow in DATE_TIME. patient's pcp thought that this might have been shingles but, per patient, the 'chicken pox' lab work came back negative. patient states that it took DATE_TIME for all of the crusting to resolve. patient continues to endorse a sense of pruritis in the area of the prior rash, but does not endorse any pain. patient has noted a slow decline in LOCATION since DATE_TIME, and in the ed on DATE_TIME noted to have an iop of DATE_TIME, va of cf@1ft. - minimal guttae od, and difficult to assess guttae os given the edema and PERSON's folds - no evidence of surface disease aside from areas of pee, some confluent, no obvious dendritic lesions - however, given this very significant history of what sounds highly suspicious for shingles in the v1 distribution on the left side back in DATE_TIME, will opt to treat the patient again at this time (concern for endotheliitis given the corneal edema that is still present despite normalized iop, and concern for LOCATION given the elevated iop previously in the ed) - will also redraw viral labs DATE_TIME: hsv1, hsv2, vzv - start valacyclovir 1g tid - start pf qid os - continue timolol, dorz, brimonidine bid each - note: patient does has asthma, but states that he has been tolerating all of his drops well without noticing any worsening of sob; will continue timolol at this time - stop latanoprost (viral concern, uveitis concern, reduce drop burden, iop improved) pmh: htn, gout, mi, triple bypass, right carotid endarterectomy, colon ca, prostate ca, bilateral hip replacement, dm2, gerd f/u - will arrange for further glaucoma and cornea follow-up",
"gpt4_summary": "Patient had a crusting rash on left forehead that was suspiciously like shingles but tested negative. A slow decline in disease was noted, the patient had high intraocular pressure previously. Has asthma but tolerates timolol well. Glaucoma and cornea follow-up arranged.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09353",
"image_path": "slo_fundus_09353.jpg",
"filename": "data_09353.npz",
"report": "Patient underwent successful laser peripheral iridectomy 2/16 ago. No glaucoma - potential signs (cupping od) but normal pressures, reassured by testing. No chalazia.",
"age": 55.07,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "1) refractive: stable 2) s/p laser peripheral iridectomy os done 2/16 ago: looks patent but is at DATE_TIME. there is no diplopia. no need for laser od as the gonio appears open 3) glaucoma susupect ou: there is cupping od, but normal pressures. all testing is reassuring. i think this is physiologic cupping od -return for baseline testing DATE_TIME to be sure dfe: 3/16 vf: 5/16 DATE_TIME gonio: 23/16 tmax: 16, 16 cct: 542, 546 fhx: 4) chalazia: gone -warm compresses bid prn",
"gpt4_summary": "Patient underwent successful laser peripheral iridectomy 2/16 ago. No glaucoma - potential signs (cupping od) but normal pressures, reassured by testing. No chalazia.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09360",
"image_path": "slo_fundus_09360.jpg",
"filename": "data_09360.npz",
"report": "Patient has glaucoma, hypertensive disorder, and Crohn's disease. Had a Humphrey visual field and optic nerve tests in both eyes. No immunizations given during visit.",
"age": 84.12,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "normal orders this visit humphrey visual field - ou - both eyes oct, optic nerve - ou - both eyes - cirrus; rnfl condition list as of DATE_TIME glaucoma hypertensive disorder crohn's disease results summary immunizations administered on date of encounter - DATE_TIME none patient gateway activation information your account is ready to use. LOCATION.",
"gpt4_summary": "Patient has glaucoma, hypertensive disorder, and Crohn's disease. Had a Humphrey visual field and optic nerve tests in both eyes. No immunizations given during visit.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09361",
"image_path": "slo_fundus_09361.jpg",
"filename": "data_09361.npz",
"report": "75 y.o. female, glaucoma suspect due to family history, experiencing problems with left eye post-cataract surgery. No glaucoma symptoms. Bifocal glasses assist vision. Mild nuclear sclerotic cataract od, defer surgery.",
"age": 75.42,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "75 y.o. female presents for follow-up visit. patient reports that 'os is not functioning well after cataract surgery'. denies diplopia, but feels that the left eye does not move normally. has no vision problems. no flashes, no floaters, no pain. \u00ff 1. glaucoma suspect - mother had glaucoma in DATE_TIME, sister diagnosed with glaucoma recently, had laser tx - iop DATE_TIME, pt reports that PERSON was around 22 per patient - optic nerves appear ok - per pt report, no hx of hvf hvf DATE_TIME test, dilated) DATE_TIME: full ou hvf DATE_TIME: non-specific defects \u00ff 2. post-op month #8 after phaco/ pciol on left patient complains of problems with os, 'not functioning well'. vision good, denies diplopia strabismus as a child but has since resolved. \u00ff unclear etiology of her symptoms possibly symptomatic from anisometropia, but hesitant to get od done, given that she is unhappy with outcome os. \u00ff has made bifocal glasses (not progressive). this helps with vision (has not done well with progressive glasses in the past). complains that she sees the lines under her eyes more since the surgery. she claims that she did not have this before. she notices a 'white' area on her inferior lid os after the surgery. mild pco os but not any more symptomatic than before. defer laser. ? 3. nuclear sclerotic cataract od - becoming visually significant - has some trouble with anisometropia, but prefers to defer surgery od at this time, not happy with outcome os. \u00ff 4. refractive error rx provided",
"gpt4_summary": "75 y.o. female, glaucoma suspect due to family history, experiencing problems with left eye post-cataract surgery. No glaucoma symptoms. Bifocal glasses assist vision. Mild nuclear sclerotic cataract od, defer surgery.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09362",
"image_path": "slo_fundus_09362.jpg",
"filename": "data_09362.npz",
"report": "Patient has pre-diabetes, is actively losing weight. There's cupping and borderline intraocular pressure, indicating potential glaucoma risk. Prescribed medication as needed, yearly checks suggested.",
"age": 71.46,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "imp: doing well with pciol ou pre-diabetic (actively losing weight) cupping and borderline iop ou ( testing normal) pvd os refr error plan: rx=m prn yrly with hvf and oct rudnick pgy4 i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow. i have reviewed the resident/fellow's notes and made any necessary changes.",
"gpt4_summary": "Patient has pre-diabetes, is actively losing weight. There's cupping and borderline intraocular pressure, indicating potential glaucoma risk. Prescribed medication as needed, yearly checks suggested.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09363",
"image_path": "slo_fundus_09363.jpg",
"filename": "data_09363.npz",
"report": "The patient is taking simvastatin 20mg tablet at night and has conditions such as hyperlipidemia, anxiety, dysfunctional uterine bleeding, and is an ex-smoker. No mention of glaucoma.",
"age": 68.16,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "simvastatin (zocor) 20 mg tablet (taking) simvastatin 20 mg tablet; dose: 20 mg; form: take 1 tablet; route: PERSON; frequency: qpm; directions: not available; details: dispense: tablet(s); status: active; source: PERSON,PERSON,p.a.-c.; date: DATE_TIME PERSON DATE_TIME received from: partners lmr your orders normal orders this visit humphrey visual field - ou - both eyes oct, optic nerve - ou - both eyes - cirrus future labs/procedures complete by expires oct, optic nerve - ou - both eyes - cirrus DATE_TIME (approximate) DATE_TIME condition list as of DATE_TIME hyperlipidemia anxiety dysfunctional uterine bleeding ex-smoker results summary immunizations administered on date of encounter - DATE_TIME none patient gateway activation information your account is ready to use. activate your account using following steps: 1. visit URL. 2. click 'enroll now' and create your user account. important information about your account: ? if you already have a account, please sign in with your username and password. ? you must log into your account within DATE_TIME or activation code will expire. ? trouble logging in? use support link found on the top right side of the login page. ? need help? support team makes every effort to respond to phone or email messages within DATE_TIME. to reach the support team, email EMAIL_ADDRESSPHONE_NUMBER. calls or messages are answered DATE_TIME, DATE_TIME, est - and will make every effort to contact you within DATE_TIME.",
"gpt4_summary": "The patient is taking simvastatin 20mg tablet at night and has conditions such as hyperlipidemia, anxiety, dysfunctional uterine bleeding, and is an ex-smoker. No mention of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09368",
"image_path": "slo_fundus_09368.jpg",
"filename": "data_09368.npz",
"report": "Patient has open angle glaucoma with borderline findings - low risk. Also has conductive hearing loss, presbyopia, tear film insufficiency, tympanic membrane perforation, hemorrhoids, lymphocytopenia, latent tuberculosis.",
"age": 46.91,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "married or partnered",
"note": "DATE_TIME a zeidman, PERSON chelsea adult medicine DATE_TIME am PERSON r LOCATION, PERSONtitution glaucoma main campus PHONE_NUMBER orders placed this visit humphrey visual field - ou - both eyes oct, optic nerve - ou - both eyes - visante condition list as of DATE_TIME middle ear conductive hearing loss open angle with borderline findings, low risk presbyopia tear film insufficiency total perforation of left tympanic membrane grade ii hemorrhoids lymphocytopenia latent tuberculosis by blood test results summary immunizations administered on date of encounter.",
"gpt4_summary": "Patient has open angle glaucoma with borderline findings - low risk. Also has conductive hearing loss, presbyopia, tear film insufficiency, tympanic membrane perforation, hemorrhoids, lymphocytopenia, latent tuberculosis.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09369",
"image_path": "slo_fundus_09369.jpg",
"filename": "data_09369.npz",
"report": "The clinical note is a reminder for an upcoming appointment with Dr. NRP Song. No information about glaucoma is mentioned in the note.",
"age": 82.63,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "DATE_TIME, DATE_TIME PERSONdick' patient: PERSON pantano mr number: NUMBER date of birth: DATE_TIME date of visit: DATE_TIME to whom it may concern: this is Institution PERSON reminding you of your upcoming appointment on DATE_TIME at DATE_TIME with dr. NRP song. your appointment may last DATE_TIME. please complete the PERSON screening questionnaire for your appointment available on patient gateway prior to your visit. as a reminder, we are asking that no more than one person accompany you to your appointment and will provide a mask for you to wear while in the office. thank you, Institution, PERSON phone: PHONE_NUMBER, option 3 fax: PHONE_NUMBER",
"gpt4_summary": "The clinical note is a reminder for an upcoming appointment with Dr. NRP Song. No information about glaucoma is mentioned in the note.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09371",
"image_path": "slo_fundus_09371.jpg",
"filename": "data_09371.npz",
"report": "The patient likely has Primary Open-Angle Glaucoma (POAG). Other conditions mentioned are Diabetes Mellitus type 2, cataracts, hyperopia/presbyopia. Decided to adjust glaucoma med to Cosopt, to control Intraocular pressure (IOP).",
"age": 72.13,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "# likely poag, moderate, ou: -previously followed by dr. PERSON (PERSON) who moved -reports tmax about 25 or 26 -pachy: DATE_TIME shows fairly diffuse thinning ou - gonio open \u00ff\u00ff # diabetes mellitus type 2, diagnosed DATE_TIME -no retinopathy >importance of blood pressure, glucose, and lipid control emphasized with patient \u00ff\u00ff \u00ff# cataracts ou -borderline visually significant, not yet affecting activities >monitor \u00ff\u00ff \u00ff\u00ff # hyperopia/presbyopia >cont wrx (received from optometrist DATE_TIME) \u00ff\u00ff plan: vf od likely stable but may be worse c/w DATE_TIME iop also too high based on cct and level of damage, set target to 15 ou discussed slt vs drops he would like to try additional drops for now change timolol to cosopt bid ou for ease of use ; rba discussed cont latanoprost ou qhs rtc 2 PERSON check in LOCATION can see me after in LOCATION or mc",
"gpt4_summary": "The patient likely has Primary Open-Angle Glaucoma (POAG). Other conditions mentioned are Diabetes Mellitus type 2, cataracts, hyperopia/presbyopia. Decided to adjust glaucoma med to Cosopt, to control Intraocular pressure (IOP).",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09372",
"image_path": "slo_fundus_09372.jpg",
"filename": "data_09372.npz",
"report": "Patient has worsening right eye Humphrey visual field; incorrect prescription used. Continuing latanoprost and timolol for left eye. Dilated exam and optical coherence tomography needed. Possible glaucoma.",
"age": 77.24,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "intervention: s/p ce/iol/ PERSONIME (LOCATION): mrx DATE_TIME humphrey visual field 24-2 standard right eye done- worsened rx used was -0.75 which i don't think is correct left: --continue latanoprost (teal cap) DATE_TIME at bedtime --continue timolol (yellow cap) DATE_TIME dilated exam: DATE_TIME DATE_TIME rnfl: DATE_TIME *needs dilated octs last visual field: DATE_TIME (unreliable) baseline disc photos: DATE_TIME, DATE_TIME disc photo both eyes on way out f/u DATE_TIME with repeat humphrey visual field sita fast both eyes (not c faster and not standard) f/u with PERSON as scheduled",
"gpt4_summary": "Patient has worsening right eye Humphrey visual field; incorrect prescription used. Continuing latanoprost and timolol for left eye. Dilated exam and optical coherence tomography needed. Possible glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09373",
"image_path": "slo_fundus_09373.jpg",
"filename": "data_09373.npz",
"report": "The patient has open angle glaucoma in both eyes with signs of worsening, in addition to early cataracts and posterior vitreous detachment. Treatment includes LOCATION, alphagan, and ltn.",
"age": 68.48,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "1. open angle glaucoma ou, referred by PERSON due to concern for worsening vfDATE_TIME ; dx in DATE_TIME no fhx, no trauma, no steroids ttarget: DATE_TIME, tmax: 21 ou cct: 554, 554, 554 / 563, 563, 563 gonioscopy: open ou rnfl oct inf and sup thinning od, inf thinning PERSON defect ou medications : LOCATION, alphagan and ltn ou 2. early cataracts ou: stable -observe 3. posterior vitreous detachment od: stable -retinal detachment 4. refractive: stable - happy without distance glasses a/p: likely sn defect ou but patient is a poor vf taker - long, unreliable tests ; unclear if any true worsening, indeed vf may be stable compared to DATE_TIME rnfl oct unchanged since DATE_TIME , however PERSON likely bottomed out iop has consistently measured bellow 12 which is likely acceptable range for patient recommend repeating vf in 3-4 mths will need to confirm true worsening before proceeding with trab ; can consider trab if having diff with drops and/or at the time ce",
"gpt4_summary": "The patient has open angle glaucoma in both eyes with signs of worsening, in addition to early cataracts and posterior vitreous detachment. Treatment includes LOCATION, alphagan, and ltn.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09375",
"image_path": "slo_fundus_09375.jpg",
"filename": "data_09375.npz",
"report": "Patient has a strong family history of glaucoma and is therefore a glaucoma suspect. Suffers from migraines but exhibits good IOP and C/D ratio and no eye pain.",
"age": 26.8,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "married or partnered",
"note": "first seen by Person on DATE_TIME. seen for routine eye exam DATE_TIME in LOCATION. has had migraines for DATE_TIME. diagnosis: glaucoma suspect by family history prior history: target iop: / , tmax: ( ) / ( ) central corneal thickness: 559 / 577 gonioscopy: ss ou, lots of iris processes refractive error: od . . / os . . optic nerve/rnfl findings on initial visit right eye (DATE_TIME): full, wnl optic nerve/rnfl findings on initial visit left eye (DATE_TIME): full, wnl visual fields on initial visit right eye (DATE_TIME): full, reliable visual fields on initial visit left eye (DATE_TIME): full, reliable medication history and intolerances at first visit: glaucoma procedures right eye: glaucoma procedures left eye: other eye procedures right eye: other eye procedures left eye: other eye problems right eye: other eye problems left eye: family history: mother, maternal aunt, maternal uncle, LOCATION -- mgm with blindness steroids: no trauma: no asthma: other medical history and problems: assessment: 1. glaucoma suspect 2/2 strong family history -baseline oct and hvf wnl -iop and c/d ratio good DATE_TIME -consanguinity in family, but parents are not related 2. right-sided headaches -no eye pain, but some over superior orbit -per patient, brain imaging wnl DATE_TIME prior plan: -monitor off of iop lowering medications -no intraocular causes for headache seen on exam DATE_TIME -discussed speaking with pcp about migraine treatment rtc in DATE_TIME in cos or glaucoma with me, iop, dilate, oct rnfl/gcipl",
"gpt4_summary": "Patient has a strong family history of glaucoma and is therefore a glaucoma suspect. Suffers from migraines but exhibits good IOP and C/D ratio and no eye pain.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09377",
"image_path": "slo_fundus_09377.jpg",
"filename": "data_09377.npz",
"report": "Patient first seen by Dr. PERSON. Diagnosis is primary angle closure suspect with normal optic nerve and visual fields. Plan includes laser iridotomy due to risks identified. Glaucoma medication history noted.",
"age": 64.52,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "first seen by dr. PERSON on DATE_TIME diagnosis: primary angle closure suspect target iop: / , tmax: ( ) / ( ) central corneal thickness: 539 / 525 gonioscopy:closed refractive error: od +4.50 . -0.75 . 015 / os +3.00 . . optic nerve findings on initial visit right eye: normal optic nerve findings on initial visit left eye: normal visual fields on initial visit right eye: normal visual fields on initial visit left eye: normal medication history and intolerances at first visit: glaucoma procedures right eye: glaucoma procedures left eye: other eye procedures right eye: other eye procedures left eye: other eye problems right eye: other eye problems left eye: family history: steroids: flonase, flovent trauma: no asthma: yes other medical history and problems: plan: i discussed the risks/benefits/alternative of laser iridotomy including but not limited to the following: prolonged inflammation, acute eye pressure elevation and glare. after this discussion, the patient elected to proceed. initial note: +4d hyperope, closed without peripheral anterior synechiae large cup:disc ratio healthy nerve, normal visual field",
"gpt4_summary": "Patient first seen by Dr. PERSON. Diagnosis is primary angle closure suspect with normal optic nerve and visual fields. Plan includes laser iridotomy due to risks identified. Glaucoma medication history noted.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09382",
"image_path": "slo_fundus_09382.jpg",
"filename": "data_09382.npz",
"report": "Patient suspected of primary open-angle glaucoma due to family history (mother) and slightly asymmetrical cup/disc ratio. Optic nerves stable, IOP in excellent range. Diplopia likely due to developing cataract.",
"age": 70.74,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "poag suspect based on +fh (mother) and slightly assymetric cup/disc ratio, average cct ? DATE_TIME: iop in excellent range optic nerves stable, humphrey visual field and optical coherence tomography normal diploplia had been previously noted os on LOCATION testing- eoms were all normal, likely secondary to developing cataract os she has her\u00ffrefraction locally ? h/o pvd ou. scattered PERSONfh of amd no retinal elevation no changes noted with amsler grid ? plan: observe, return visit DATE_TIME for iop check, and humphrey visual field optical coherence tomography both eyes .",
"gpt4_summary": "Patient suspected of primary open-angle glaucoma due to family history (mother) and slightly asymmetrical cup/disc ratio. Optic nerves stable, IOP in excellent range. Diplopia likely due to developing cataract.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09388",
"image_path": "slo_fundus_09388.jpg",
"filename": "data_09388.npz",
"report": "The patient is prescribed levalbuterol for wheezing, Ativan for anxiety, and spironolactone. Various conditions listed, including hypercholesterolemia, hypertension, sleep apnea, and cataracts. No mention of glaucoma.",
"age": 65.96,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "levalbuterol (PERSON) 45 mcg/actuation inhaler inhale 2 puffs into the lungs every 6 (DATE_TIME as needed for wheezing. PERSON (ativan) 0.5 mg tablet take 1 tablet by mouth as needed for anxiety spironolactone (aldactone) 50 mg tablet take 1 tablet (50 mg total) by mouth DATE_TIME. your orders future appointments provider department dept phone DATE_TIME PERSON, PERSONtitution endocrine associates 617-726-8720 DATE_TIME 10:15 am PERSON pulm lab cox pft1 PERSON pulmonary and critical care unit 617-726-1200 DATE_TIME 11:00 am PERSON, PERSONtitution pulmonary associates PHONE_NUMBER orders placed this visit humphrey visual field - ou - both eyes oct, optic nerve - ou - both eyes - optical biometry - ou - both eyes condition list as of DATE_TIME homocystinemia colon polyp hypercholesterolemia chronic sinusitis essential hypertension diarrhea depressive disorder hyperaldosteronism adrenal nodule posterior vitreous detachment epiretinal membrane (erm) of right eye lattice degeneration of peripheral retina cataracts, both eyes coronary artery disease enzyme disorder chest pain sleep apnea other chest pain word finding difficulty discharge planning issues diplopia dyspnea angina pectoris coronary artery disease involving native coronary artery of native heart without angina pectoris acute pain of right knee onychia of toe of right foot numerous moles results summary immunizations administered on date of encounter - DATE_TIME none",
"gpt4_summary": "The patient is prescribed levalbuterol for wheezing, Ativan for anxiety, and spironolactone. Various conditions listed, including hypercholesterolemia, hypertension, sleep apnea, and cataracts. No mention of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09394",
"image_path": "slo_fundus_09394.jpg",
"filename": "data_09394.npz",
"report": "Patient has mild glaucoma due to past lens removal for ectopia lentis. Repeat Humphrey visual field and dilated OCT retinal nerve fiber layer tests needed. If intraocular pressure exceeds 10-11, referral to neuro-ophthalmology advised.",
"age": 25.34,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "threshold to refer to neuro-ophthalmology if there is progression at intraocular pressure of 10-11. PERSON has mild glaucoma ou secondary to s/p lens removal for ectopia lentis and PERSON ou, here for repeat humphrey visual field both eyes (24-2 both eyes, to check and make sure these have stabilized) and dilated optical coherence tomography retinal nerve fiber layer. *low threshold to refer to neuro-ophthalmology if there is progression at intraocular pressure of 10-11. continue latanoprost qhs both eyes dorzolamide bid ou last dilated exam: DATE_TIME DATE_TIME rnfl: DATE_TIME last visual field: DATE_TIME baseline disc photos: DATE_TIME return to glaucoma clinic DATE_TIME for intraocular pressure check on the dorzolamide PERSON acting as scribe for dr. PERSON on DATE_TIME at DATE_TIME.",
"gpt4_summary": "Patient has mild glaucoma due to past lens removal for ectopia lentis. Repeat Humphrey visual field and dilated OCT retinal nerve fiber layer tests needed. If intraocular pressure exceeds 10-11, referral to neuro-ophthalmology advised.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09396",
"image_path": "slo_fundus_09396.jpg",
"filename": "data_09396.npz",
"report": "The patient is suspected by their doctor of having glaucoma in both eyes based on several factors, including a family history of the disease (the patient's mother and sister). They display normal intraocular pressure and central corneal thickness. No medication or procedures for glaucoma have been conducted. Patient also has red-green color blindness.",
"age": 26.66,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "first seen by PERSON PERSON on DATE_TIME diagnosis: glaucoma suspect of both eyes based on cup:disc ratio and fhx (patient's mom is df patient) target iop: DATE_TIME, tmax: ( ) / ( ) central corneal thickness: 567 / 577 corneal hysteresis: 10.3/10.1 gonioscopy: open to ciliary body band both eyes refractive error: od . . / os . . optic nerve findings on initial visit right eye: full optic nerve findings on initial visit left eye: full visual fields on initial visit right eye: full visual fields on initial visit left eye: full medication history and intolerances at first visit: none glaucoma procedures right eye: none glaucoma procedures left eye: none other eye procedures right eye: none other eye procedures left eye: none other eye problems right eye: none other eye problems left eye: none family history: mother (has had glaucoma surgeries, no blindness)- diagnosed in DATE_TIME, sister (28 yo) with ocular hypertension on drops steroids: none trauma: none asthma: none other medical history and problems: red-green color blindness initial note: strong fhx DATE_TIME glaucoma with mom diagnosed at DATE_TIME and sister who is on drops for ocular hypertension at DATE_TIME. unknown tmax but per patient intraocular pressure has never been high. normal central corneal thickness (567, 577). intraocular pressure within normal limits DATE_TIME and optical coherence PERSON visual field are full. observe off drops for now with DATE_TIME follow up given strong fhx. plan: intraocular pressure acceptable off drops no glaucoma damage on testing continue to observe off drops for now return to clinic DATE_TIME for dilation, optical coherence tomography and humphrey visual field",
"gpt4_summary": "The patient is suspected by their doctor of having glaucoma in both eyes based on several factors, including a family history of the disease (the patient's mother and sister). They display normal intraocular pressure and central corneal thickness. No medication or procedures for glaucoma have been conducted. Patient also has red-green color blindness.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09398",
"image_path": "slo_fundus_09398.jpg",
"filename": "data_09398.npz",
"report": "Patient has genetically confirmed Leber's hereditary optic neuropathy causing paracentral vision loss. Vision has improved to 20/20 right eye and 20/15 left eye, but mild dyschromatopsia and central scotomas remain. The note does not indicate presence of glaucoma.",
"age": 38.94,
"gender": "male",
"race": "white",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "married or partnered",
"note": "formulation: this patient returns for follow up of paracentral vision loss and genetically confirmed leber's hereditary optic neuropathy (DATE_TIME mutation). my exam revealed improved visual acuity with 20/20 in the right eye, and 20/15 in the left eye. he had mild dyschromatopsia, and bilateral central scotomas on visual fields that have been stable. oct showed reduced ganglion cell segmentation layer in both eyes. it is very good that his vision has improved, and this sometimes happens sometimes in this condition. i advised him that good nutrition and avoidance of toxins such as cigarettes and alcohol is essential. i will see him again in DATE_TIME. this patient presents with progressive visual loss ou, with mostly a paracentral vision loss. he has now tested positively for the leber's DATE_TIME mutation. \u00ff his neuro-ophthalmic exam is notable for significantly improved acuity ou DATE_TIME with 20/20 vision, although he frequently completely misses individual letters, mild dyschromatopsia, poor central vision on amsler grid, bilateral central scotomas on visual fields and bilateral optic nerve pallor, all consistent with a bilateral optic neuropathy. \u00ff i counseled him extensively regarding the new diagnosis of leber's. it is very good that his vision has improved, and this sometimes happens sometimes in this condition. i advised him that good nutrition and avoidance of toxins such as cigarettes and alcohol is essential. i will see him again in DATE_TIME. impression: 1. bilateral optic neuropathy secondary to lhon (DATE_TIME mutation), with significant visual recovery plan: 1. follow-up neuro-ophthalmic examination in DATE_TIME this note was prepared with the assistance of PERSON, md, neuro-ophthalmology fellow. PERSON neuro-ophthalmology LOCATION PHONE_NUMBER fax PHONE_NUMBER",
"gpt4_summary": "Patient has genetically confirmed Leber's hereditary optic neuropathy causing paracentral vision loss. Vision has improved to 20/20 right eye and 20/15 left eye, but mild dyschromatopsia and central scotomas remain. The note does not indicate presence of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09401",
"image_path": "slo_fundus_09401.jpg",
"filename": "data_09401.npz",
"report": "The clinical note doesn't provide any specific details about the patient's condition, including the presence of glaucoma.",
"age": 80.95,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "the resident/fellow's notes and made any necessary changes. i, PERSON, am acting as scribe for PERSONmd, PERSON for patient PERSON on DATE_TIME. - PERSON",
"gpt4_summary": "The clinical note doesn't provide any specific details about the patient's condition, including the presence of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09410",
"image_path": "slo_fundus_09410.jpg",
"filename": "data_09410.npz",
"report": "67 y.o. patient has history of high iop with oil and extensive laser treatment, suspect glaucoma due to optic nerve cupping. Maternal grandmother had glaucoma. Patient also has a nuclear cataract and history of laser retinopexy. Patient has steroid response, but iop is good for now. Opted not to have secondary iol surgery.",
"age": 67.79,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "67 y.o. new patient to me referred by dr. PERSON for glaucoma suspect eval # glaucoma suspect ou due to optic nerve cupping os > od - h/o high iop with oil, h/o extensive laser - maternal grandmother had glaucoma - hvf DATE_TIME od full os superior rim artifact - oct DATE_TIME od thin sup os thin sup/PERSON excellent 15/14 > monitor for now. will repeat testing in a DATE_TIME # nuclear cataract od - explains myopic shift, per patient from -3 d to -6 d - bcva 20/25+ > observe for now, she wants to avoid cataract surgery for now. > reeval in DATE_TIME # hst od s/p laser retinopexy DATE_TIME kriegstein and DATE_TIME comander - increased flashes (DATE_TIME) - retina attached DATE_TIME on exam # h/o recurrent LOCATION with pvr - s/p 23 g sor /fax PERSON from ac/ 14% c3 f8 os (DATE_TIME) - sp sb/ ppl/el/ret /afx/ silicone oil (1000) os (DATE_TIME) - s/p laser retinopexy os (DATE_TIME) - s/p ce (phaco)/23gppv/pfo/el/rr/fax os (DATE_TIME) - s/p ppv/mp/el/14% c3f8 os (DATE_TIME) - retina attached on exam # trace erm os # hx of cme os off acular since DATE_TIME hx of trace intraretinal cysts, resolved DATE_TIME on DATE_TIME DATE_TIME - stable # aphakia os has aphakic cl va ph 20/40 discussed secondary iol in past, but patient not interested cont glasses and cl when tolerable # hx of steroid response os - excellent iop now # NRP lesion - likely old chalazion fu DATE_TIME, mrx, repeat hvf/ oct",
"gpt4_summary": "67 y.o. patient has history of high iop with oil and extensive laser treatment, suspect glaucoma due to optic nerve cupping. Maternal grandmother had glaucoma. Patient also has a nuclear cataract and history of laser retinopexy. Patient has steroid response, but iop is good for now. Opted not to have secondary iol surgery.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09411",
"image_path": "slo_fundus_09411.jpg",
"filename": "data_09411.npz",
"report": "78 y.o. white, non-hispanic male diagnosed with glaucoma. Emergency contact available for on-call glaucoma physician.",
"age": 78.27,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "a 78 y.o. white, non-hispanic male was evaluated and diagnosed with glaucoma. PHONE_NUMBER (LOCATION). for emergencies, please call PHONE_NUMBER and ask for the glaucoma physician on-call.",
"gpt4_summary": "78 y.o. white, non-hispanic male diagnosed with glaucoma. Emergency contact available for on-call glaucoma physician.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09412",
"image_path": "slo_fundus_09412.jpg",
"filename": "data_09412.npz",
"report": "Patient has hypertension, proliferative diabetic retinopathy with macular edema, type 2 diabetes mellitus, bilateral pseudophakia, and epiretinal membrane. No mention of glaucoma.",
"age": 64.85,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "Return in about 6 months (around DATE) for IOP Check. Orders Placed this Visit Automated Visual Field, Extended - OU - Both Eyes OCT, Optic Nerve - OU - Both Eyes - Cirrus; Optic Disc; ONH Cube Condition List as of DATE Hypertension Proliferative diabetic retinopathy of both eyes with macular edema associated with type 2 diabetes mellitus Bilateral pseudophakia Epiretinal membrane (ERM) of both eyes Results Summary Immunizations Administered on Date of Encounter - DATE",
"gpt4_summary": "Patient has hypertension, proliferative diabetic retinopathy with macular edema, type 2 diabetes mellitus, bilateral pseudophakia, and epiretinal membrane. No mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09416",
"image_path": "slo_fundus_09416.jpg",
"filename": "data_09416.npz",
"report": "67 y.o. white, non-hispanic male diagnosed with glaucoma during a neuro-ophthalmology evaluation.",
"age": 67.47,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "a 67 y.o. white, non-hispanic male was evaluated and diagnosed with glaucoma. fellow or review of medical tests) and finalizing the note.] dean PERSON, PERSON neuro-ophthalmology LOCATION PHONE_NUMBER fax PHONE_NUMBER",
"gpt4_summary": "67 y.o. white, non-hispanic male diagnosed with glaucoma during a neuro-ophthalmology evaluation.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09417",
"image_path": "slo_fundus_09417.jpg",
"filename": "data_09417.npz",
"report": "The patient has pseudoexfoliation glaucoma, particularly severe in the left eye (os). They show ineffective response to rhopressa and intolerances to timolol/latanoprost and combigan. Trabeculectomy has been suggested.",
"age": 84.88,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "first seen by PERSON PERSON on DATE_TIME, LOCATION patient diagnosis: pseudoexfoliation glaucoma, pre-perimetric od on vf DATE_TIME although with moderate to severe stage defects with dr. LOCATION. severe stage os. here for second opinion after recommending trabeculectomy os. target iop: DATE_TIME, tmax: 20 (DATE_TIME) / 25 ( ) central corneal thickness: 599 / 642 gonioscopy: DATE_TIME: open ou refractive error: od . . / os . . optic nerve findings on initial visit right eye: glaucoma, small optic nerve findings on initial visit left eye: borderline visual fields on initial visit right eye: scattered defects visual fields on initial visit left eye: ia > sa. medication history and intolerances: os burning with timolol/latanoprost. dry mouth with combigan and ineffective per pt. poor response to rhopressa glaucoma procedures right eye: glaucoma procedures left eye: slt os DATE_TIME, no effect (LOCATION) other eye procedures right eye: PERSONE other eye procedures left eye: s/p complex phaco/ppv/lensectomy/aciol DATE_TIME other eye problems right eye: other eye problems left eye: family history: none steroids: +cream prn intermittently. trauma: none asthma: none other medical history and problems: plan: continue zioptan qhs ou (started DATE_TIME), intraocular pressure above target, but testing mostly stable. may need much lower intraocular pressure in which case may need trabeculectomy",
"gpt4_summary": "The patient has pseudoexfoliation glaucoma, particularly severe in the left eye (os). They show ineffective response to rhopressa and intolerances to timolol/latanoprost and combigan. Trabeculectomy has been suggested.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09419",
"image_path": "slo_fundus_09419.jpg",
"filename": "data_09419.npz",
"report": "The 73 y.o. female patient has moderate cataract, refractive error, blepharitis, posterior vitreous detachment, and pterygium. Glaucoma is not mentioned. She left before seeing the doctor.",
"age": 73.3,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "73 y.o. female with PERSON note: pt left prior to seeing md or having testing. she had an appointment for her hemoptysis that she was eager to get to. will reschedule for DATE_TIME. prior note: 1. PERSON, treated DATE_TIME and restarted therapy with ethambutol 1000mg mg po as of DATE_TIME on healthy ou hvf od reliable and full hvf os reliable, one point defect superior paracentral (new - ? due to toxicity vs artifact, plan to repeat next time) dp stable plan: continue to monitor for toxicity closely with serial eye exams, hvfs, color testing DATE_TIME or prn sooner for any change in vision pt weighs 114 lbs, so her dose is ~ 19.3 mg/kg/day 2. moderate cataract is present that is becoming visually significant os. observation at this time was recommended. pt not bothered. 3. refractive error: a prescription for new glasses was given to the patient DATE_TIME. recommend svd for driving and svn for reading, trouble with bifocals in the past. 4. blepharitis: good relief with short course of blephamide, then stopped as directed. wc/lh at prn 5. posterior vitreous detachment ou: no retinal holes, tears, or detachment on exam. retinal detachment precautions were reviewed with the patient. 6. pterygium od, nvs, observe f/u check va, iop, color, hvf 24-2, dilate PERSON scribing for dr. PERSON at 8:41 am on DATE_TIME. i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "The 73 y.o. female patient has moderate cataract, refractive error, blepharitis, posterior vitreous detachment, and pterygium. Glaucoma is not mentioned. She left before seeing the doctor.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09423",
"image_path": "slo_fundus_09423.jpg",
"filename": "data_09423.npz",
"report": "61-year-old patient with history of hypertension, diabetes, and sleep apnea suspected of having glaucoma due to increased cup/disc ratio. Also has moderate nonproliferative diabetic retinopathy and macular edema, improving with anti-VEGF injections, cataracts, and refractive error.\n",
"age": 61.68,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "61 f, tufts rn, hx htn, dm, osa last a1c 9.3 on DATE_TIME for f/u glaucoma testing. # glaucoma suspect with increased cup/disc ratio, both eyes. states that she had been monitored as a glaucoma suspect for DATE_TIME without a positive diagnosis of glaucoma. [ gonio DATE_TIME: open 360 ou [ oct DATE_TIME: borderline thinning PERSON, full os (stable) [ hvf DATE_TIME: dec rel and generalized depression with nonspecific superior defect od, generalized depression but full os - overall improving performance on visual field testing. - no intervention required at this time. continue to monitor. # cataract, both eyes. not visually significant in both eyes. - discussed elective cataract surgery in the future though not indicated at this time. - continue to monitor. # moderate nonproliferative diabetic retinopathy, both eyes, with clinically significant macular edema, both eyes. significantly improving with anti-vegf injections in both eyes. - f/u with PERSON, next appt DATE_TIME - reviewed with patient the importance of blood glucose and blood pressure control in the prevention of ocular and systemic complications. # hx of transient monocular vision loss (DATE_TIME). found to have mild (20%) bilateral carotid stenosis, with unrevealing brain mri and echocardiogram. - saw PERSON (neurology) in DATE_TIME # refractive error, doing well with current glasses. rtc to me DATE_TIME, sooner as needed",
"gpt4_summary": "61-year-old patient with history of hypertension, diabetes, and sleep apnea suspected of having glaucoma due to increased cup/disc ratio. Also has moderate nonproliferative diabetic retinopathy and macular edema, improving with anti-VEGF injections, cataracts, and refractive error.\n",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09426",
"image_path": "slo_fundus_09426.jpg",
"filename": "data_09426.npz",
"report": "Patient on brimonidine and dorzolamide for glaucoma, declines latanoprost/rhopressa due to side effects. Also has cataract and dermatitis. May need cataract extraction + trabeculectomy.",
"age": 75.71,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "brimonidine, does not wish to try latanoprost or rhopressa due to concern for side effects. at last visit DATE_TIME with dr. PERSON, added dorzolamide right eye twice a day for monocular trial. \u00ff also has cataract. \u00ff got worse at intraocular pressure in mid/upper teens current assessment & plan intraocular pressure at target both eyes. needs low intraocular pressure given previous progression. with dermatitis DATE_TIME, possible rhopressa? stop rhopressa continue timolol patient may need phaco/trab given low intraocular pressure goals return in DATE_TIME to see if it is still up and if so, likely cataract extraction + trabeculectomy relevant orders humphrey visual field - ou - both eyes (completed) other visit diagnoses research study patient - primary return in DATE_TIME (around DATE_TIME) for iop.",
"gpt4_summary": "Patient on brimonidine and dorzolamide for glaucoma, declines latanoprost/rhopressa due to side effects. Also has cataract and dermatitis. May need cataract extraction + trabeculectomy.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09427",
"image_path": "slo_fundus_09427.jpg",
"filename": "data_09427.npz",
"report": "The clinical note mentions a Humphrey visual field test and an Optic Nerve Cirrus condition test for both eyes. There's no direct mention of glaucoma. Other conditions include hypertension, hypercholesterolemia, and arthritis.",
"age": 61.13,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "humphrey visual field - ou - both eyes DATE_TIME (approximate) DATE_TIME orders placed this visit humphrey visual field - ou - both eyes oct, optic nerve - ou - both eyes - cirrus condition list as of DATE_TIME hypertensive disorder hypercholesterolemia arthritis results summary immunizations administered on date of encounter - DATE_TIME none patient gateway activation information your account is ready to use. activate your account using following steps:",
"gpt4_summary": "The clinical note mentions a Humphrey visual field test and an Optic Nerve Cirrus condition test for both eyes. There's no direct mention of glaucoma. Other conditions include hypertension, hypercholesterolemia, and arthritis.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09428",
"image_path": "slo_fundus_09428.jpg",
"filename": "data_09428.npz",
"report": "The patient has primary open angle glaucoma with severe condition in the right eye and mild in left. No history of glaucoma procedures or drug intolerances. Also, suffers from cataracts and diabetes.",
"age": 61.72,
"gender": "male",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "first seen by dr. PERSON on DATE_TIME diagnosis: primary open angle glaucoma target iop: 18/18 / , tmax: 24/23 ( ) / ( ) central corneal thickness: 547 / 563 gonioscopy: tm initially both eyes refractive error: od . . / os . . optic nerve findings on initial visit right eye: large cdr, thin superior optic nerve findings on initial visit left eye: large cdr visual fields on initial visit right eye: non-specific visual fields on initial visit left eye: non-specific medication history and intolerances: none glaucoma procedures right eye: none glaucoma procedures left eye: none other eye procedures right eye: none other eye procedures left eye: none other eye problems right eye: cataract, dm without dr other eye problems left eye: cataract, dm without PERSON family history: none steroids: none trauma: none asthma: albuterol inhaler other medical history and problems: plan: #primary open angle glaucoma, severe right, mild left -last seen DATE_TIME as a glaucoma suspect, then lost to follow up. re-presents DATE_TIME with new dense superior arcuate defect right eye, iop 18/16 on latanoprost but he did not have intraocular pressure checked at all from DATE_TIME -needs target low teens right eye and mid left eye given rapid progression -discussed LOCATION, drops - he wishes to try drops first -continue latanoprost qhs both eyes -start dorzolamide/timolol twice a day both eyes -f/u DATE_TIME iop check. #cataracts ou may be visually significant, but pt asymptomatic",
"gpt4_summary": "The patient has primary open angle glaucoma with severe condition in the right eye and mild in left. No history of glaucoma procedures or drug intolerances. Also, suffers from cataracts and diabetes.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09433",
"image_path": "slo_fundus_09433.jpg",
"filename": "data_09433.npz",
"report": "The 71-year-old patient, despite having disc hemorrhage, displayed no signs of glaucoma in the given exam. They have mild nonproliferative diabetic retinopathy and have been referred to the retina service.",
"age": 71.43,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "71 y.o. new patient to me DATE_TIME, used to work in the computer field, pmh: PERSON, cad, htn, hyperlipidemia, former patient of dr. PERSON last visit with PERSON, was found to have disc hemorrhage os # disc hemorrhage os - iop wnl - pachymetry 533/521 DATE_TIME - hvf DATE_TIME and DATE_TIME (borderline reliability) full ou - DATE_TIME wnl ou, DATE_TIME wnl ou > no signs of glaucoma ou on exam DATE_TIME > repeat hvf/ DATE_TIME # type 2 diabetes mellitus with mild nonproliferative diabetic retinopathy ou hemoglobin a1c date value ref range status DATE_TIME 7.8 (h) 4.3 - 5.6 % final comment: hba1c levels 5.7-6.4% represent pre-diabetes, indicating impaired glucose control and an increased risk of developing diabetes compared with lower hba1c levels. the diagnostic hba1c level for diabetes is 6.5% or greater. > requested referral to retina svc for further evaluation. he is very concerned about potential vision loss and would like more information about his condition. now follows with PERSON > importance of blood pressure, blood sugar and lipid control emphasized # combined cataracts ou - not visually significant > observe # cobblestone degeneration os # dermatochalasis ou # lll eyelid lesions > referral to oculoplastics for excision fu DATE_TIME, mrx, bat, dilate, repeat hvf/oct \u00ff i saw and evaluated this patient and discussed the case as appropriate with the resident. i have reviewed the resident's notes and made any necessary changes. PERSON",
"gpt4_summary": "The 71-year-old patient, despite having disc hemorrhage, displayed no signs of glaucoma in the given exam. They have mild nonproliferative diabetic retinopathy and have been referred to the retina service.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09436",
"image_path": "slo_fundus_09436.jpg",
"filename": "data_09436.npz",
"report": "The patient is using Plaquenil, with an unchanged eye examination. The patient may have pigmentary glaucoma with family history (father), with an elevated intraocular pressure in the right eye. Patient advised to wean off steroids to avoid increased IOP. Open angle observed in both eyes. Patient also has allergy/dry eye issues.",
"age": 68.19,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "plaquenil use 200mg bid - started DATE_TIME baseline plaquenil hvf 10-2 ou done. hvf 10-2 wnl ou. OCT Mac OU WNL. . patients pcp has lower the dose. reassured pt. recommend yearly plaquenil eye exam. ?pigmentary glaucoma +fmhx (dad), race. iop is elevated od normal os. PERSON -1 ou. hvf DATE_TIME WNL ou. oct rnfl normal ou. gcl normal ou. continue latanoprost qhs ou pt started steroid injections to scalp since DATE_TIME, as well as steroid ointment pt reported they are currently waning off steroids, encouraged pt to keep waning off use b/c steroids often increase IOP Gonio (DATE_TIME): 3-4+ pigmented tm od; 2-3+ pigmented tm os multiple iris processes ou open angle not occludable ou sarcoid diagnose DATE_TIME no breathing trouble pt takes steroid injections in scalp -- pcp stopped injections hemoglobin a1c date value ref range status DATE_TIME 5.3 4.8 - 5.9 % final recommend to check her a1c pvd od seen at ed DATE_TIME for this. no holes or tears. warned of rd symptoms. pt reports occasional flashes at DATE_TIME, but does not notice floaters. pigmented ring od > os observe DATE_TIME allergies/drye eye gave pt seasonal allergy handout recommend at's prn, allergy /Drye eye, and allergy testing avoid heat/rubbing/allergens avoid visine and other medications that 'get the red out' avoid flonase and other steroidal medications avoid decongestant 'd' variants of allergy meds follow up in DATE_TIME for iop, oct.",
"gpt4_summary": "The patient is using Plaquenil, with an unchanged eye examination. The patient may have pigmentary glaucoma with family history (father), with an elevated intraocular pressure in the right eye. Patient advised to wean off steroids to avoid increased IOP. Open angle observed in both eyes. Patient also has allergy/dry eye issues.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09438",
"image_path": "slo_fundus_09438.jpg",
"filename": "data_09438.npz",
"report": "The patient has been prescribed Latanoprost for potential glaucoma, with an option to consider selective laser trabeculoplasty. Their next checkup for intraocular pressure is scheduled.",
"age": 75.84,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "eyes start latanoprost qhs both eyes -- printed rx given. pt will consider starting this versus selective laser trabeculoplasty. pt still consider LOCATION last dilated exam: DATE_TIME DATE_TIME rnfl: DATE_TIME last visual field:DATE_TIME baseline disc photos: DATE_TIME return to glaucoma clinic DATE_TIME with intraocular pressure check on ltn or selective laser trabeculoplasty depending on pt's preference PERSON acting as scribe for dr. PERSON on DATE_TIME at DATE_TIME.",
"gpt4_summary": "The patient has been prescribed Latanoprost for potential glaucoma, with an option to consider selective laser trabeculoplasty. Their next checkup for intraocular pressure is scheduled.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09443",
"image_path": "slo_fundus_09443.jpg",
"filename": "data_09443.npz",
"report": "The patient shows no signs of retinal vasculitis. She experiences shadow OS due to PVD and has asymmetrical cup to disc ratio (OD 0.3, OS 0.45). OCT RNFL indicates slight superior thinning OS. Glaucoma presence is not indicated.",
"age": 54.76,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "This has completely resolved on initial exam 2/2019. If she had retinal vasculitis previously, the systemic treatment she has received (IV solumedrol, PO Prednisone, IV Rituxan and PO Cytoxan) would be appropriate to induce resolution. - On exam today, she has no evidence of retinal vasculitis. - normal OCT macula - FA 3/27/19 2. PVD OS - discussed with patient likely cause of shadow OS; no retinal tears/holes - monitor 3. Cup to disc asymmetry -- noted on exam at outside facility - prior records from 2015 with documented asymmetry (documented as OD 0.3, OS 0.45) - full visual fields OU 3/2019 - OCT RNFL with slight thinning superiorly OS; healthy rim on exam - monitor RTC 3 months",
"gpt4_summary": "The patient shows no signs of retinal vasculitis. She experiences shadow OS due to PVD and has asymmetrical cup to disc ratio (OD 0.3, OS 0.45). OCT RNFL indicates slight superior thinning OS. Glaucoma presence is not indicated.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09447",
"image_path": "slo_fundus_09447.jpg",
"filename": "data_09447.npz",
"report": "Ms. PERSON has nodules in lung apices and recurrent blurred vision. Cause of the vision loss is unclear, not typical of migraine or retinal vasospasm. Glaucoma is suspected, requiring monitoring.",
"age": 55.36,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "arteries. 3. PERSON nodules in the visualized lung apices with areas of pleural-parenchymal thickening. dedicated ct chest for further evaluation is suggested. impression and reccomendations: in summary, the etiology of ms. PERSON's recurrent blurred vision remains unclear. despite her accompanying photophobia, the duration of her symptoms is not typical of a migrainous process or retinal vasospasm, and her examination and recent vascular imaging do not reveal typical features of ocular ischemic syndrome. consideration may be given to a refractive process such as ocular surface disease or cataracts, although her symptoms are somewhat disproportionate to her examination findings. as a result, despite the absence of overt afferent dysfunction on examination, consideration may be given to evaluation for a retinal cause of her striking photophobia and nyctalopia, particularly if her symptoms do not improve with conservative management. as noted previously, the etiology of ms. PERSON's recurrent, prolonged vision loss following strenuous exercise is also unclear, but has been reported in patients with glaucoma, perhaps reflecting iop elevation or vascular steal; as a result, continued monitoring of ms. PERSON's perimetry and iop may be informative. i will plan to see ms. PERSON in follow-up in DATE_TIME, although she understood to contact me sooner with any questions or concerns. thank you for the opportunity to participate in ms. PERSON's care. sincerely, PERSON, LOCATION were spent during this encounter and in reviewing the medical record, exclusive of procedures.",
"gpt4_summary": "Ms. PERSON has nodules in lung apices and recurrent blurred vision. Cause of the vision loss is unclear, not typical of migraine or retinal vasospasm. Glaucoma is suspected, requiring monitoring.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09450",
"image_path": "slo_fundus_09450.jpg",
"filename": "data_09450.npz",
"report": "The patient, a non-smoker, has visual acuity measured as dist sc 20/50 for both eyes. No eyeglass prescription found. No known allergies. Conditions include Retinitis Pigmentosa, visual field defect, and edema of optic nerve. No mention of glaucoma.",
"age": 8.95,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "PERSON of birth: DATE_TIME patient PERSON: NUMBER Institution neuro oph LOCATION dept phone #: PHONE_NUMBER dept fax #: PHONE_NUMBER mario mcminn DATE_TIME office visit mrn: NUMBER provider: PERSON, LOCATION: Institution neuro oph main campus patient demographics address phone e-mail address 264 LOCATION street newton DATE_TIME_NUMBER (home) PHONE_NUMBER (mobile) *preferred* EMAIL_ADDRESS information date of birth sex race ethnicity preferred language preferred written language DATE_TIME male white or NRP no NRP NRP reason for visit new evaluation vital signs/measurements smoking status never smoker your visual acuity as measured during DATE_TIME's visit (snellen - linear) right left dist sc 20/50 20/50 dist ph sc ni 20/40 near sc j2 j1+ no eyeglass prescription found allergies as of DATE_TIME no known allergies medications and orders your orders future labs/procedures complete by expires fundus photos - ou - both eyes as directed DATE_TIME oct, optic nerve - ou - both eyes - cirrus; optic disc; onh cube, rnfl, gcc as directed DATE_TIME condition list as of DATE_TIME retinitis pigmentosa visual field defect edema of optic nerve results summary immunizations administered on date of encounter - DATE_TIME none",
"gpt4_summary": "The patient, a non-smoker, has visual acuity measured as dist sc 20/50 for both eyes. No eyeglass prescription found. No known allergies. Conditions include Retinitis Pigmentosa, visual field defect, and edema of optic nerve. No mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09451",
"image_path": "slo_fundus_09451.jpg",
"filename": "data_09451.npz",
"report": "Patient has pigmentary glaucoma and cataracts in both eyes, and compound astigmatism with presbyopia. They're educated on glaucoma's effects and informed regular checks are crucial. Declined cataract consultation for now. New glasses prescription given.",
"age": 76.27,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "married or partnered",
"note": "assessment: 1. pigmentary glaucoma ou - monitored by dr. Person 2. cataracts ou - not visually significant 3. compound PERSON astigmatism with presbyopia ou plan: 1. educated patient on how glaucoma effects vision. told patient that glaucoma is associated with high eye pressures and that it must be checked every visit. family history is a risk factor. educated that yearly eye appointments are necessary to rule out any start of glaucoma and that those that do not return may end up with worse vision due to undiagnosed glaucoma. verbal understanding. continue care with dr. PERSON as instructed. 2. educated patient on findings DATE_TIME. educated patient that their condition is associated with age/uv light/or specific systemic diseases that lead to progression of the lens inside their eye to become cloudy. educated patient that surgery is the only method of removing cataract. patient declines cataract consultation at this time. monitor DATE_TIME. 3. new spectacle prescription given to patient DATE_TIME. adaptation to new prescription discussed. verbal understanding. return DATE_TIME for comprehensive eye exams with dr. PERSON at longwood optometry. sooner if vision worsens, redness/pain occur, or any other visual anomalies occur.",
"gpt4_summary": "Patient has pigmentary glaucoma and cataracts in both eyes, and compound astigmatism with presbyopia. They're educated on glaucoma's effects and informed regular checks are crucial. Declined cataract consultation for now. New glasses prescription given.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09455",
"image_path": "slo_fundus_09455.jpg",
"filename": "data_09455.npz",
"report": "The patient has ocular hypertension in both eyes with high IOP. Gonioscopy presented 2+ OU. Retinal nerve fiber layer showed no thinning. Visual fields were full. She also has a history of herpetic keratitis in the left eye. No signs of glaucoma.",
"age": 45.16,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "first seen by dr. PERSON on DATE_TIME glaucoma medication intolerances: n/a target iop: DATE_TIME, tmax: 26 / 28 central corneal thickness: 507 / 524 gonioscopy: PERSON 2+ ou retinal nerve fiber layer, right eye: no thinning retinal nerve fiber layer, left eye: no thinning visual fields, right eye: full visual fields, left eye: full family history: father, paternal grandfather, uncle steroids: none trauma: none asthma/copd: asthma other medical history and problems: htn, migraine, depression assessment/plan: 45 y.o. female nurse # ocular hypertension, both eyes - iop too high ou - continue to monitor without initiating topical treatment - return DATE_TIME as scheduled for iop check, PERSON, biometry, and bilateral selective laser trabeculoplasty as per coast trial protocol # history of herpetic keratitis, left eye (DATE_TIME) - mild epithelial scarring -",
"gpt4_summary": "The patient has ocular hypertension in both eyes with high IOP. Gonioscopy presented 2+ OU. Retinal nerve fiber layer showed no thinning. Visual fields were full. She also has a history of herpetic keratitis in the left eye. No signs of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09459",
"image_path": "slo_fundus_09459.jpg",
"filename": "data_09459.npz",
"report": "Primary angle closure glaucoma diagnosis, worse in left eye than right eye. Increased intraocular pressure, worsening visual field. Previous treatments include latanoprost and laser procedures. Allergic reaction to timolol, brimonidine or cosopt pf. Stable, keep current management.",
"age": 73.8,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "first seen by PERSON PERSON on DATE_TIME diagnosis: primary angle closure glaucoma left eye > right eye. visual field got worse with intraocular pressure in the 22 range. target iop: / , tmax: ( ) / ( ) target 16 central corneal thickness: / gonioscopy: refractive error: od . . / os . . optic nerve findings on initial visit right eye: optic nerve findings on initial visit left eye: visual fields on initial visit right eye: inferior paracentral visual fields on initial visit left eye: inferior arcuate, encroaching onto fixation , enlarged blind spot medication history and intolerances at first visit: latanoprost, PERSON bid ou. had allergic reaction to timolol or brimonidine or cosopt pf glaucoma procedures right eye: laser peripheral iridotomy, selective laser trabeculoplasty glaucoma procedures left eye: laser peripheral iridotomy ,selective laser trabeculoplasty other eye procedures right eye: none other eye procedures left eye: none other eye problems right eye: none other eye problems left eye: none family history: none steroids: none trauma: patient had an electrocuted in DATE_TIME and had some 'bleeding in the eye' asthma: none other medical history and problems: knee pain plan: iop excellent, continue present management. mostly stable exam DATE_TIME",
"gpt4_summary": "Primary angle closure glaucoma diagnosis, worse in left eye than right eye. Increased intraocular pressure, worsening visual field. Previous treatments include latanoprost and laser procedures. Allergic reaction to timolol, brimonidine or cosopt pf. Stable, keep current management.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09467",
"image_path": "slo_fundus_09467.jpg",
"filename": "data_09467.npz",
"report": "51 y.o. Asian, non-Hispanic female, no diagnosis of glaucoma. Encounter recorded and information verified as complete and accurate.",
"age": 51.78,
"gender": "female",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "a 51 y.o. asian, non-hispanic female with no diagnosis of glaucoma. encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "51 y.o. Asian, non-Hispanic female, no diagnosis of glaucoma. Encounter recorded and information verified as complete and accurate.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09473",
"image_path": "slo_fundus_09473.jpg",
"filename": "data_09473.npz",
"report": "Patient is taking various medications including Docusate Sodium, Finasteride, Efudex, Lorazepam, Mometasone, Singulair, Omega-3 Fatty Acids, Polyethylene Glycol, Senna, Tamsulosin, and Verapamil. Has conditions like heart disease, benign prostatic hyperplasia, erectile dysfunction, hypertension, dry eye syndrome, pupillary miosis and IFIS. No mention of glaucoma.",
"age": 80.36,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "docusate sodium (colace) 100 mg capsule (taking) take 100 mg by mouth 2 (two) times a day. reported on DATE_TIME finasteride (proscar) 5 mg tablet (taking) take 1 tablet (5 mg total) by mouth DATE_TIME. PERSON (efudex) 5 % cream (taking) apply 1 application topically 2 (two) times a day. apply twice a day for DATE_TIME to area on right cheek; abhijit wakle DATE_TIME metal med transfer process lorazepam (ativan) 0.5 mg tablet (taking) reported on DATE_TIME william r cannon, LOCATION 2:17 pm received from: partners healthcare mometasone (elocon) 0.1 % cream (taking) apply topically DATE_TIME as needed. PERSON (singulair) 10 mg tablet (taking) take 10 mg by mouth DATE_TIME as needed. reported on DATE_TIME omega-3 fatty acids/fish oil (omega 3 fish oil oral) (taking) take by mouth. polyethylene glycol (glycolax) 17 gram packet (taking) take 17 g by mouth DATE_TIME. reported on DATE_TIME PERSON DATE_TIME 4:09 am metal med transfer process senna (senokot) 8.6 mg tablet (taking) take 2 tablets by mouth 2 (two) times a day. reported on DATE_TIME abhijit wakle DATE_TIME 4:09 am metal med transfer process tamsulosin (flomax) 0.4 mg cp24 (taking) take 1 capsule (0.4 mg total) by mouth DATE_TIME. verapamil (LOCATION) 200 mg (taking) take 1 capsule (200 mg total) by mouth DATE_TIME. your orders normal orders this visit humphrey visual field - ou - both eyes oct, optic nerve - ou - both eyes - cirrus condition list as of DATE_TIME heart disease PERSON (benign prostatic hyperplasia) erectile dysfunction hypertension dry eye syndrome pupillary miosis tamsulosin-associated intraoperative floppy iris syndrome (ifis) results summary immunizations administered on date of encounter - DATE_TIME none",
"gpt4_summary": "Patient is taking various medications including Docusate Sodium, Finasteride, Efudex, Lorazepam, Mometasone, Singulair, Omega-3 Fatty Acids, Polyethylene Glycol, Senna, Tamsulosin, and Verapamil. Has conditions like heart disease, benign prostatic hyperplasia, erectile dysfunction, hypertension, dry eye syndrome, pupillary miosis and IFIS. No mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09482",
"image_path": "slo_fundus_09482.jpg",
"filename": "data_09482.npz",
"report": "Patient has glaucoma and mild optic atrophy, which is currently stable. No signs of chordoma recurrence. He's experiencing memory issues potentially linked to radiation. A follow-up surveillance MRI and an outpatient ophthalmology visit are needed.\n",
"age": 68.62,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "his glaucoma, although he also needs to be monitored for radiation-induced optic nerve damage. overall, his mild optic atrophy appears stable currently. there are no findings that would suggest chordoma recurrence. he also describes some memory problems, which could be related to the radiation exposure. my plan: - follow up surveillance mri next at Institution given possible changes on recent mri. - follow up with outpatient ophthalmologist for consideration of cataract extraction od. i gave him several recommendations DATE_TIME - he again deferred neuropsychological testing given patient's reports of memory disturbance following radiation treatment i will see the patient again in DATE_TIME to reassess progress, sooner if new symptoms arise in the interim. thank you for allowing me to participate in the care of your patient. please do not hesitate to call with questions. ? sincerely, PERSON, LOCATION neuro-ophthalmology, headache unit, and inflammatory neuro-ophthalmology/skull base disorders clinic. division of neuroimmunology, Institution neuro-ophthalmology, Institution i personally spent DATE_TIME preparing for, caring for the patient (face-to-face and non-face-to-face), and finalizing the visit for this patient. this time excludes any listed procedures.",
"gpt4_summary": "Patient has glaucoma and mild optic atrophy, which is currently stable. No signs of chordoma recurrence. He's experiencing memory issues potentially linked to radiation. A follow-up surveillance MRI and an outpatient ophthalmology visit are needed.\n",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09485",
"image_path": "slo_fundus_09485.jpg",
"filename": "data_09485.npz",
"report": "The patient is on medication including sildenafil, antihypertensive, vitamin D3, and atorvastatin. Medical conditions include head injury, hyperlipidemia, sarcoidosis, kidney stone, bipolar disorder, hemochromatosis, diabetes type 2, glaucoma.",
"age": 52.07,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "LOCATION mohanty DATE_TIME needs PERSON. metal med transfer process. sildenafil, antihypertensive, (revatio) 20 mg tablet (taking) take 1 tablet (20 mg total) by mouth once as needed. vitamin d3 2,000 unit tablet (taking) take 1 tablet twice daily atorvastatin (lipitor) 20 mg tablet take 1 tablet (20 mg total) by mouth nightly. your orders normal orders this visit humphrey visual field - ou - both eyes oct, optic nerve - ou - both eyes - cirrus; rnfl condition list as of DATE_TIME injury of head hyperlipidemia sarcoidosis kidney stone bipolar disorder hemochromatosis carrier dm (diabetes mellitus), type 2 glaucoma at risk for obstructive sleep apnea pain in joint of left shoulder right foot drop healthcare maintenance results summary immunizations administered on date of encounter - DATE_TIME none",
"gpt4_summary": "The patient is on medication including sildenafil, antihypertensive, vitamin D3, and atorvastatin. Medical conditions include head injury, hyperlipidemia, sarcoidosis, kidney stone, bipolar disorder, hemochromatosis, diabetes type 2, glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09487",
"image_path": "slo_fundus_09487.jpg",
"filename": "data_09487.npz",
"report": "68-year-old manager with various health issues. Suspected of having Primary Open-Angle Glaucoma (POAG) due to c/d ratio 0.7 ou, but does not have a family history of glaucoma. Noted that despite cataract surgery, dry eye irritation will persist.",
"age": 68.26,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "68 PERSON manager with history of htn, hypercholesterolemia, cad s/p cabg DATE_TIME (couper), LOCATION, osteoarthritis of knee s/p r knee surgery 9/12, afib/vtach now s/p pacer (on coumadin, goal 2-3) asa 81 mg metal k abrasion os many years ago (evaluated by dr. post) DATE_TIME saw dr. PERSON for fb under lid os >> removed in office referred for cataract evaluation by PERSON rhee 1. s/p phaco/pciol ou (od DATE_TIME and os DATE_TIME, toric ou) deep brow. coumadin with LOCATION generally around 2.5 (does not want topical) pentacam DATE_TIME: PERSON. PERSON, doing well. 2. poag suspect (by c/d ratio 0.7 ou) tmax 21 ou (DATE_TIME), previously 17/19. cct 590/595 (thick). no fhx glaucoma hvf DATE_TIME: full ou hvf DATE_TIME: full ou oct 3/DATE_TIME: wnl ou oct DATE_TIME: wnl ou dp DATE_TIME >> followed by PERSON/turalba, felt stable at last visit DATE_TIME (likely physiologic cupping) >> will follow. DATE_TIME. pvd ou -floaters os for many years (od is finer) 4. mgd ou -used azasite and wc in past. now on optive bid which helps his baseline irritation >> understands dry eye/irritation will persist despite cataract surgery, and may still cause some glare",
"gpt4_summary": "68-year-old manager with various health issues. Suspected of having Primary Open-Angle Glaucoma (POAG) due to c/d ratio 0.7 ou, but does not have a family history of glaucoma. Noted that despite cataract surgery, dry eye irritation will persist.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09490",
"image_path": "slo_fundus_09490.jpg",
"filename": "data_09490.npz",
"report": "54 year-old female with sarcoidosis, significant dry eye, mild cataracts, potential glaucoma; follow-up in 6-12 months. Left clinic unattended; case discussed with resident/fellow.",
"age": 54.08,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "54 F with sarcoid Previously seen by Dr. PERSON Imp: 1. Significant dry eye OU - rec AT QID and WC, consider plugs in future 2. Mild cat OU - monitor, myopic shift today since 2011 (was plano OU in 2011) 3. Ref err - Mrx today 4. Sarcoid - no hx eye involvement, none today 5. Glc suspect: OCT/HVF acceptable, IOP borderline, CCT slightly thick/protective Plan: Repeat testing in 6-12mo PERSON: Patient angry that she was told she has a 'macular nerve' problem and didn't understand why she was here. After an extensive explanation by me, patient said she did not want to be seen by Dr. PERSON and left the exam room. She understands that her evaluation is incomplete without an evaluation by the attending and leaving before being seen is leaving AMA. She expressed understanding. I discussed the case as appropriate with the resident/fellow. I have reviewed the resident/fellow's notes and made any necessary changes.",
"gpt4_summary": "54 year-old female with sarcoidosis, significant dry eye, mild cataracts, potential glaucoma; follow-up in 6-12 months. Left clinic unattended; case discussed with resident/fellow.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09491",
"image_path": "slo_fundus_09491.jpg",
"filename": "data_09491.npz",
"report": "79 y.o. female eye patient with past cataract surgery and degenerative drusen. Tested for glaucoma due to increased cup to disc ratio, no signs at the moment. She struggles with near vision.",
"age": 79.39,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "79 y.o. female presents for a comprehensive eye exam and glaucoma testing. last seen by dr. PERSON for degenerative drusen of both eyes. since the last visit she still feels that the left eye is not as good for near as it was previously. 1. PERSON cataract surgery ou in LOCATION - monovision od aimed for distance - os aimed for reading per patient, se of os is -0.875, can read at near without spectacles - new mrx given to patient DATE_TIME, recommend fill rx or use otc readers for near 2. glaucoma suspect - glaucoma suspect based on increased cup to disc ratio - iop - 11/10 - tmax - 11/11 - cct - 535/508 - c/d - 0.55. 0.5 - family history - negative per patient - last hvf performed - DATE_TIME - non-specific defects od > os - last oct rnfl performed - DATE_TIME - full ou - baseline fundus photos obtained - DATE_TIME - dilated optic nerve exam performed ou at last visit - discussed potential for progressive irreversible vision loss due to glaucomatous optic neuropathy. - no evidence of glaucomatous optic neuropathy on clinical exam and testing DATE_TIME, although hvf shows peripheral defects od > os, recommend repeat testing - return in DATE_TIME with repeat hvf. 3. PERSON macula performed - DATE_TIME, on macular drusen noted rtc 2-3 months for repeat hvf 24-2 (os first, then od) then gonio with me, no dilation the above note was recorded by PERSON brewer as a scribe for dr. PERSON (DATE_TIME). \u00ff i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate. \u00ff PERSON, md",
"gpt4_summary": "79 y.o. female eye patient with past cataract surgery and degenerative drusen. Tested for glaucoma due to increased cup to disc ratio, no signs at the moment. She struggles with near vision.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09499",
"image_path": "slo_fundus_09499.jpg",
"filename": "data_09499.npz",
"report": "50-year-old unknown black female, no diagnosis of glaucoma, account ready to use at patient gateway.",
"age": 50.77,
"gender": "female",
"race": "black",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "married or partnered",
"note": "a 50 y.o. black, Unknown female with no diagnosis of glaucoma. administered on date of encounter - DATE_TIME none patient gateway activation information your account is ready to use. LOCATION.",
"gpt4_summary": "50-year-old unknown black female, no diagnosis of glaucoma, account ready to use at patient gateway.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09500",
"image_path": "slo_fundus_09500.jpg",
"filename": "data_09500.npz",
"report": "Patient referred for glaucoma assessment. Diagnosis: mild POAG(Primary Open-Angle Glaucoma) OD (right eye), OHTN (ocular hypertension) OS (left eye). Inferior RNFL (Retinal Nerve Fiber Layer) in right eye looks thinner than left. Plan: start latanoprost.",
"age": 62.3,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "first seen by Person on DATE_TIME. referred by dr. PERSON for glaucoma evaluation. diagnosis: mild POAG OD, ohtn os Target IOP: / , tmax: ( ) / ( ) central corneal thickness: 521 / 523 gonioscopy: cbb, 1-3+ pigment refractive error: od . . / os . . optic nerve/rnfl findings on baseline visit right eye (DATE_TIME): 0.45, but inferior rnfl looks thinner than left eye optic nerve/rnfl findings on baseline visit left eye (DATE_TIME): 0.2, full visual fields on baseline visit right eye (DATE_TIME): full visual fields on baseline visit left eye (DATE_TIME): full medication history at first visit: medication intolerances: glaucoma procedures right eye: glaucoma procedures left eye: other eye procedures right eye: other eye procedures left eye: other eye problems right eye: other eye problems left eye: family history: sister (surgery), mother steroids: no trauma: no asthma: no other medical history and problems: assessment: 1. mild POAG OD, ohtn os -inferior rnfl od looks thinner than left eye 2. ns cataracts ou -not yet significant -monitor plan: -start latanoprost 1/1 rtc in DATE_TIME for dfe",
"gpt4_summary": "Patient referred for glaucoma assessment. Diagnosis: mild POAG(Primary Open-Angle Glaucoma) OD (right eye), OHTN (ocular hypertension) OS (left eye). Inferior RNFL (Retinal Nerve Fiber Layer) in right eye looks thinner than left. Plan: start latanoprost.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09503",
"image_path": "slo_fundus_09503.jpg",
"filename": "data_09503.npz",
"report": "The patient is an 83-year-old woman with a history of hypertension, osteoarthritis, and vertigo. She underwent right knee arthroplasty in 2019. She is suspected of having glaucoma, but no family history. She also has blepharitis, punctal ectropion, trichiasis, and mild hypertensive retinopathy, and is under treatment for these.",
"age": 83.65,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "83 yo woman with history of HTN, osteoarthritis, vertigo (saw Dr. PERSON, no episodes since treated with his therapist Dr. PERSON) S/p R total knee arthroplasty 9/5/19 \u00ff 1. Glaucoma suspect (c/d ratio) Tmax 18 OU (24 OD on POD#1). CCT 545/542 (ave). No FHx glacuoma Followed by Dr. PERSON in past HVF 10/4/22: Full OU HVF 8/24/21: OD full. OS superior rim loss HVF 8/4/20: full OU HVF 7/23/19: full OU HVF 7/10/18: full OU HVF 5/22/15: full OU HVF 5/23/14: full OU (isolated loss inferiorly) OCT 10/4/22: WNL OU OCT 8/24/21: WNL OU OCT 8/4/20: WNL OU OCT 7/23/19: WNL OU OCT 7/10/18: WNL OU OCT 6/20/17: WNL OU OCT 6/7/16: WNL OU OCT 5/22/15: WNL OU OCT 5/23/14: WNL OU \u00ff 2. s/p phaco/PCIOL OU (10/25/07 OD and 1/24/08 OS; Dr. PERSON OU) Mild PCO OS> OD; off visual axis, asx >> updated MRx 10/4/22 \u00ff 3. Blepharitis OU with MGD -Exam severe today with thickened eyelids OU with telangiectasis >> expressed MG OU today -Performing WCs with showers >> WC/LH. Will add Azasite scrubs x 2 wks. Continue EMN ung x 1-2 wks QHS prn >> may consider doxycyline in future \u00ff 4. Punctal ectropion OS>OD, appears to have spastic component (lids occluding each other's puncta) >> epiphora and some mucous, also component of blepharitis/MGD. Will consider plastics eval \u00ff 5. RLL trichiasis and LLL trichiasis >> asx, will follow 6. Mild hypertensive retinopathy (AV nicking OU) >> monitor patanol PRN vernal sx",
"gpt4_summary": "The patient is an 83-year-old woman with a history of hypertension, osteoarthritis, and vertigo. She underwent right knee arthroplasty in 2019. She is suspected of having glaucoma, but no family history. She also has blepharitis, punctal ectropion, trichiasis, and mild hypertensive retinopathy, and is under treatment for these.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09508",
"image_path": "slo_fundus_09508.jpg",
"filename": "data_09508.npz",
"report": "The patient has mild primary open-angle glaucoma in the left eye and is a glaucoma suspect in the right eye. Father had glaucoma diagnosed at age 90. No signs of high intraocular pressure. Patient also has dry eye and pseudophakia.",
"age": 68.87,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "# poag os (mild), and suspect od: - fhx glaucoma in father (dx 90 yo) - no known h/o high iop, gonio open - diagnosis of glaucoma/glaucoma suspect discussed with patient - review of natural history and management options discussed. importance of lifelong follow up and adherence to treatments discussed in order to lower risk of permanent vision loss/blindness from glaucoma. all questions answered. \u00ff\u00ff # dry eye, evaporative mild rosacea -hc ou bid -at ou bid-tid -omega iii fa po \u00ff\u00ff # pseudophakia ou: - monitor, per hatch \u00ff plan: good effect with LOCATION ou qhs, ccm \u00ff cc: dr. PERSON- 4 months repeat hvf",
"gpt4_summary": "The patient has mild primary open-angle glaucoma in the left eye and is a glaucoma suspect in the right eye. Father had glaucoma diagnosed at age 90. No signs of high intraocular pressure. Patient also has dry eye and pseudophakia.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09509",
"image_path": "slo_fundus_09509.jpg",
"filename": "data_09509.npz",
"report": "82-year-old white, non-Hispanic female, no diagnosis of glaucoma, completed COVID prescreening.",
"age": 82.31,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "a 82 y.o. white, non-hispanic female with no diagnosis of glaucoma. covid prescreening complete.",
"gpt4_summary": "82-year-old white, non-Hispanic female, no diagnosis of glaucoma, completed COVID prescreening.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09510",
"image_path": "slo_fundus_09510.jpg",
"filename": "data_09510.npz",
"report": "Patient has cataract in both eyes, experiences glare at night, and is a glaucoma suspect due to c/d asymmetry. Past surgeries include strabismus surgery and eyelid ptosis repair. Dry vs recurrent corneal erosion. Plan: yearly eye exam.",
"age": 80.16,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "imp: cataract ou - noticing glare at night - monitor glaucoma suspect based on c/d asymmetry - fhx: +father - tmax: 18/19; DATE_TIME 12/14 - cct 499/498 - hvf DATE_TIME normal ou; oct with stable sup thinning ou - angles open by gonio thyroid eye disease: h/o graves disease s/p radioactive iodine DATE_TIME, nonsmoker - s/p strabismus surgery (dr. PERSON) DATE_TIME internal recession lul with tarsal posterior spacer graft from lul to lll DATE_TIME - s/p right upper eyelid ptosis repair via external levator advancement, and left upper eyelid recession DATE_TIME lul recession DATE_TIME - followed by dr. PERSON and tufts endocrinology vortex keratopathy --amiodarone x DATE_TIME dry vs. recurrent corneal erosion od --gel/oint hs refr error plan: yrly exam with hvf and oct",
"gpt4_summary": "Patient has cataract in both eyes, experiences glare at night, and is a glaucoma suspect due to c/d asymmetry. Past surgeries include strabismus surgery and eyelid ptosis repair. Dry vs recurrent corneal erosion. Plan: yearly eye exam.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09511",
"image_path": "slo_fundus_09511.jpg",
"filename": "data_09511.npz",
"report": "The female patient, an employee with a history of breast cancer, is suspected to have glaucoma based on cup:disc ratio and possible pigment dispersion syndrome. Continued monitoring and repeat tests are recommended. She also has posterior vitreous detachment, dry eyes, and refractive error.",
"age": 64.95,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "DATE_TIME. female PERSON employee with h/o breast ca on tamoxifen - glaucoma suspect based on cup:disc ratio ou with possible pigment dispersion syndrome fam hx: none tmax (here): 21/20 cct: 570/580 gonio DATE_TIME: open to cbb 360, no pas, 2+ pigmented tm hvf DATE_TIME: ou reliable and full DATE_TIME: od nasal defects, os full rnfl DATE_TIME: ou wnl DATE_TIME: PERSON but decreasing avg nfl, PERSON and stable gcl DATE_TIME: ou wnl disc photos: DATE_TIME, DATE_TIME, DATE_TIME last dilated: DATE_TIME >> continue to monitor closely, particularly avg nfl od. plan to repeat hvf soon - posterior vitreous detachment ou last dfe by PERSON DATE_TIME showed pvd ou no new retinal holes/tears DATE_TIME >> retinal detachment precautions - mild dry eye syndrome ou notes itching/irritation around fall time every year >> chilled preservative-free artificial tears, zaditor ou bid prn - refractive error >> a prescription for new glasses was given to the patient DATE_TIME. repeat hvf od soon f/up DATE_TIME with mrx, bat, hvf, rnfl oct, dilation, sooner prn",
"gpt4_summary": "The female patient, an employee with a history of breast cancer, is suspected to have glaucoma based on cup:disc ratio and possible pigment dispersion syndrome. Continued monitoring and repeat tests are recommended. She also has posterior vitreous detachment, dry eyes, and refractive error.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09512",
"image_path": "slo_fundus_09512.jpg",
"filename": "data_09512.npz",
"report": "Patient has multiple meningiomas likely caused by exogenous estrogen intake, one lesion compressing optic nerve. History of open angle glaucoma in both eyes. Follow-up required for glaucoma management.",
"age": 79.68,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "that development of multiple meningiomas might have occurred secondary to the exogenous estrogen which is very plausible given that many meningiomas express estrogen receptors. diagnoses. 1. multiple meningiomas, one lesion causing prechiasmal optic nerve compression 2. history of open angle glaucoma both eyes 3. PERSON syndrome, with history of long-time exogenous estrogen intake that likely influenced #1 4. convergence PERSON recommendations. 1. follow up in DATE_TIME with hvf, oct gcc and rnfl 2. follow up with dr. PERSON DATE_TIME with surveillance mri 3. refer to comprehensive ophthalmololgy for glaucoma management; i will refill latanoprost but not PERSON, PERSON, neuro-ophthalmology service (this note was prepared with the assistance of dr. PERSON, md, neuro-ophthalmology resident.) ----- [administrative formulation. my impression of this case is based upon an assessment of the the patient's acute / chronic problems as detailed under 'diagnoses' above that pose a threat to vision / neurological function or systemic health. my assessment of this case also included review of the following data: 1) results of tests and outside documents (specifically: a review of prior external notes; review of unique test results (including those described under 'ancillary studies' above); ordering unique tests; assessment requiring independent historian - daughter);dr. PERSON, dr. PERSON 2) independent interpretation of tests performed by dr. PERSON 3) discussion or communication or management with dr. PERSON, dr. PERSON with respect to management, this patient has a high risk of morbidity related to therapy/elective or major surgery/decision regarding PERSON.]",
"gpt4_summary": "Patient has multiple meningiomas likely caused by exogenous estrogen intake, one lesion compressing optic nerve. History of open angle glaucoma in both eyes. Follow-up required for glaucoma management.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09513",
"image_path": "slo_fundus_09513.jpg",
"filename": "data_09513.npz",
"report": "Patient has primary open angle glaucoma in both eyes. Condition is stable as per optical coherence tomography and automated perimetry. No need for drops.",
"age": 29.74,
"gender": "male",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "plan: #primary open angle glaucoma (poag) of both eyes, suspect - optical coherence tomography, automated perimetry stable, intraocular pressure around baseline - can continue to monitor for now off drops",
"gpt4_summary": "Patient has primary open angle glaucoma in both eyes. Condition is stable as per optical coherence tomography and automated perimetry. No need for drops.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09514",
"image_path": "slo_fundus_09514.jpg",
"filename": "data_09514.npz",
"report": "The patient is to take ergocalciferol 400 unit tablet and fingolimod 0.5mg capsule. Orders for fundus photography, visual field testing and optic nerve were placed. No mention of glaucoma.",
"age": 40.14,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "ergocalciferol 400 unit tablet take 1 tablet by mouth DATE_TIME. LOCATION pawar DATE_TIME 1:25 am metal med transfer process fingolimod (gilenya) 0.5 mg cap take 1 capsule (0.5 mg total) by mouth DATE_TIME. your orders future appointments provider department dept phone DATE_TIME bwh amb infusion chair 14 bwh ambulatory infusion center DATE_TIME DATE_TIME PERSON, PERSON partners ms and infusion center 617-525-6550 DATE_TIME DATE_TIME PERSON amb infusion chair PERSON ambulatory infusion center DATE_TIME DATE_TIME, PERSON and women's hospital, department of neurology PHONE DATE_TIME 11:00 am PERSON, LOCATION shore physicians group 7 DATE_TIME 10:00 am PERSON, PERSONtitution neuro oph main campus PHONE_NUMBER orders placed this visit color fundus photography - ou - both eyes humphrey visual field - ou - both eyes oct, optic nerve - ou - both eyes - cirrus; gcc, rnfl condition list as of DATE_TIME multiple sclerosis results summary immunizations administered on date of encounter - DATE_TIME none",
"gpt4_summary": "The patient is to take ergocalciferol 400 unit tablet and fingolimod 0.5mg capsule. Orders for fundus photography, visual field testing and optic nerve were placed. No mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09519",
"image_path": "slo_fundus_09519.jpg",
"filename": "data_09519.npz",
"report": "The 26-year-old patient has keratoconus and significant thinning in the left eye, possible hydrops, and was advised about potential surgery. Patient is also a glaucoma suspect due to increased c/d; no trauma or steroid use.",
"age": 26.99,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "26 PERSON here for follow up referred by PERSON wore scleral lenses x DATE_TIME (rgp before that) works in information security # keratoconus os > od diagnosed at ~14 yo #s/p cxl od (DATE_TIME) kmax DATE_TIME 66.4/79.7 (thinnest 351/142) - last used scleral lenses DATE_TIME DATE_TIME 67.0/82.6 wore scleral lenses DATE_TIME DATE_TIME 67.1/75.5 wore scleral lenses DATE_TIME (just out) some fluctuation in scans, no ob progression profound thinning os > od with scarring, possible hydrops discussed alk/pkp surgery os.appears too thin for cxl but could consider in attempt to stabilize tissue around cone will monitor at this time and consider in the future. pt would PERSON to avoid surgery if possible add gel tear qhs # seasonal allergies - no eye rubbing zaditor bid prn # neovascularization of cornea monitor # glaucoma suspect due to increased c/d no fhx, no steroid use, no trauma cct thin due to kc appears full , will monitor fu DATE_TIME pent compare",
"gpt4_summary": "The 26-year-old patient has keratoconus and significant thinning in the left eye, possible hydrops, and was advised about potential surgery. Patient is also a glaucoma suspect due to increased c/d; no trauma or steroid use.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09520",
"image_path": "slo_fundus_09520.jpg",
"filename": "data_09520.npz",
"report": "The clinical note does not provide any specific details about the presence of glaucoma.",
"age": 81.6,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "and then afterwards in DATE_TIME with intraocular pressure check PERSON acting as scribe for dr. PERSON on DATE_TIME at DATE_TIME.",
"gpt4_summary": "The clinical note does not provide any specific details about the presence of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09525",
"image_path": "slo_fundus_09525.jpg",
"filename": "data_09525.npz",
"report": "The patient has glaucoma and has undergone eye procedures. They have history of asthma, bradycaryia, and renal dysfunction/kidney stones. They are allergic to sulfa. Their condition is being monitored with various glaucoma tests and procedures.",
"age": 68.03,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "procedures/lasers: other eye procedures/lasers: glaucoma medication issues: {positive and negative:22522} history of asthma {positive and negative:22522} history of bradycardia {positive and negative:22522} sulfa allergy {positive and negative:22522} history of renal disfuntion or kidney stones testing: baseline DATE_TIME (DATE_TIME) hvf- od, sup arcuate; os, generalized depression - no prior for comparison (DATE_TIME) hvf 10-2 os DATE_TIME: small central island (DATE_TIME, PERSON thinning; os, generalized thinning \u00ff # cataract ou - mild, monitor for now # plan DATE_TIME: iop not recorded , {blank single:19197::'acceptable','too high','too low'} od, {blank single:19197::'acceptable','too high','too low'} os last dilated exam: DATE_TIME DATE_TIME rnfl: DATE_TIME last visual field: DATE_TIME baseline disc photos: DATE_TIME return to glaucoma clinic",
"gpt4_summary": "The patient has glaucoma and has undergone eye procedures. They have history of asthma, bradycaryia, and renal dysfunction/kidney stones. They are allergic to sulfa. Their condition is being monitored with various glaucoma tests and procedures.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09529",
"image_path": "slo_fundus_09529.jpg",
"filename": "data_09529.npz",
"report": "55 y.o. male diagnosed with advanced primary open angle glaucoma, worse in right eye. No medication intolerance reported. Corneal thickness 564/567. Plan includes Xalatan, Timolol, and possibility of surgery. Also, borderline cataracts.",
"age": 55.52,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "unknown",
"note": "attending's assessment and plan: 55 y.o. male - primary open angle glaucoma, advanced ou, od worse than os. PERSON, 24 os on treatment. positive fhx. medication intolerance: none central corneal thickness: 564/ 567 goal PERSON around 10, os around 10 - elevated ou in DATE_TIME. plan: c/w xal ou qhs. add timolol ou bid and PERSON ou bid. - pt may need procedure/ surgery if iop is not better controlled soon. - cataracts, borderline vs plan: monitor - systemic / social: pt is from PERSON. y - rtc in DATE_TIME for iop ou, hvf 10-2 ou and oct ou.",
"gpt4_summary": "55 y.o. male diagnosed with advanced primary open angle glaucoma, worse in right eye. No medication intolerance reported. Corneal thickness 564/567. Plan includes Xalatan, Timolol, and possibility of surgery. Also, borderline cataracts.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09531",
"image_path": "slo_fundus_09531.jpg",
"filename": "data_09531.npz",
"report": "The patient is a glaucoma suspect with no family history, 20/20 vision, and normal OCT. Also presents with posterior vitreous detachment and retinal gland dysfunction/dry eye syndrome. No new floaters/tears/holes/detachments.",
"age": 62.27,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "glaucoma suspect based on cup:disc appearance ou fam hx: none tmax: 20/20, PERSON is 0 od -1 os. gonio DATE_TIME: ou open to ss/cbb hvf DATE_TIME: ou full hvf DATE_TIME: ou full. rnfl oct DATE_TIME: ou PERSON oct DATE_TIME: ou wnl disc photos: DATE_TIME observe. posterior vitreous detachment ou symptom onset od DATE_TIME, os 9-DATE_TIME no retinal tears/holes/detachment on dilated exam DATE_TIME no new floaters DATE_TIME (persistent old floaters) retinal detachment precautions discussed PERSON gland dysfunction/dry eye syndrome ou treatment with warm compresses,artificial tears discussed last visit chorioretinal punched out pigmented lesion od ?operculum flat. patient reports she has been made aware of this lesion which has remained unchanged for DATE_TIME. observe refractive error new rx given. f/u in DATE_TIME for oct, NRP, ar/refract.",
"gpt4_summary": "The patient is a glaucoma suspect with no family history, 20/20 vision, and normal OCT. Also presents with posterior vitreous detachment and retinal gland dysfunction/dry eye syndrome. No new floaters/tears/holes/detachments.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09534",
"image_path": "slo_fundus_09534.jpg",
"filename": "data_09534.npz",
"report": "The patient is a 23-year-old healthy female with ocular hypertension in both eyes. No glaucoma present. No thinning of retinal nerve fiber layer observed. Undergoing monitoring.",
"age": 23.85,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "first seen by dr. PERSON on DATE_TIME glaucoma medication intolerances: none target iop: DATE_TIME, tmax: 27 / 27 central corneal thickness: 609 / 610 gonioscopy: d40f 1+ ou retinal nerve fiber layer, right eye: no thinning retinal nerve fiber layer, left eye: no thinning visual fields, right eye: full visual fields, left eye: full family history: none steroids: none trauma: none asthma/copd: none other medical history and problems: generally healthy assessment/plan: 23 y.o. female investment banker # ocular hypertension, both eyes - iop borderline ou - discussed monitoring for now, and future treatments could include drops like latanoprost or selective laser trabeculoplasty - continue to monitor without initiating treatment - return in DATE_TIME for iop check, dilate, disc photos PERSON, md",
"gpt4_summary": "The patient is a 23-year-old healthy female with ocular hypertension in both eyes. No glaucoma present. No thinning of retinal nerve fiber layer observed. Undergoing monitoring.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09535",
"image_path": "slo_fundus_09535.jpg",
"filename": "data_09535.npz",
"report": "64 y.o. male referred for glaucoma suspect evaluation due to optic disc cupping. Tests were within normal limits. Mild cataracts and dry eye noted, no glaucoma or ocular issues found.\n",
"age": 64.4,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "64 y.o. male s/p stem cell transplant (unrelated donor) DATE_TIME referred by dr. PERSON for glaucoma suspect eval \u00ff \u00ff # glaucoma suspect based on optic disc cupping - tcurrent: 18/16 - tmax: 18/17 - central corneal thickness: DATE_TIME: DATE_TIME wnl ou DATE_TIME PERSON - hvf: DATE_TIME essentially full DATE_TIME full - family history: none - race: NRP >? low risk. observe # incipient cataract both eyes - not visually significant > observe # family hx of amd (mother) - no signs of amd # dry eye ou s/p stem cell transplant - no signs of ocular PERSON > sees dr. PERSON, last visit DATE_TIME # ll punctal ectropion - initially symptomatic but no longer tearing > observe # refractive error > updated glasses prescription given per request for distance glasses fu DATE_TIME, mrx, dilate",
"gpt4_summary": "64 y.o. male referred for glaucoma suspect evaluation due to optic disc cupping. Tests were within normal limits. Mild cataracts and dry eye noted, no glaucoma or ocular issues found.\n",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09536",
"image_path": "slo_fundus_09536.jpg",
"filename": "data_09536.npz",
"report": "Patient has symptoms in right eye, visual field defect. Left eye shows nasal defect. Unclear link to past hemiplegic migraine. MRI brain will be done. History of chronic kidney disease present.",
"age": 29.55,
"gender": "female",
"race": "black",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "single",
"note": "patient localizes all her symptoms to the temporal field in the right eye, but the hvf in the left eye DATE_TIME shows a clear nasal defect. it is not clear how the patient's report of right eye temporal vision loss occurring during her hemiplegic migraine (that ostensibly recovered) is linked with her more recent vision loss. there may have been a single event that then partially recovered before the patient rediscovered her symptoms of peripheral field loss vs. there being 2 separate events. i will obtain an mri brain with contrast. we will check her kidney function DATE_TIME given her history of ckd. i will contact her with the results. ? impression: 1. possible right homonymous visual field defect 2. chronic kidney disease ? recommendations: 1. mri brain with contrast 2. labs DATE_TIME: bun, creatinine it is a pleasure to participate in the care of this patient. please do not hesitate to call with questions. ? sincerely, ? PERSON, PERSON spent DATE_TIME with this patient, more than 50% of which was face to face with the patient.",
"gpt4_summary": "Patient has symptoms in right eye, visual field defect. Left eye shows nasal defect. Unclear link to past hemiplegic migraine. MRI brain will be done. History of chronic kidney disease present.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09537",
"image_path": "slo_fundus_09537.jpg",
"filename": "data_09537.npz",
"report": "63-year-old female suspected of Glaucoma. Referral from optometry for Intraocular Pressure evaluation. Not tolerating NRP. Questions about Cosopt effectiveness. Family history positive.",
"age": 63.99,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "63 yo f glaucoma suspect referred by optometry for evaluation as her ophthalmologists wants to PERSON for her iop. poag suspect, PERSON; cct 566/579. currently on cosopt bid, ou. did not tolerate NRP in the past. i question whether cosopt is effective. there is no definitive vf loss family hx is positive for grand mother, but no close siblings. plan hold cosopt for now. hold on laser treatment f/u in DATE_TIME with LOCATION--oct",
"gpt4_summary": "63-year-old female suspected of Glaucoma. Referral from optometry for Intraocular Pressure evaluation. Not tolerating NRP. Questions about Cosopt effectiveness. Family history positive.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09538",
"image_path": "slo_fundus_09538.jpg",
"filename": "data_09538.npz",
"report": "50 y.o. white, Hispanic female diagnosed with glaucoma. Will be out of town at a specified date/time.",
"age": 50.18,
"gender": "female",
"race": "white",
"ethnicity": "hispanic",
"language": "spanish",
"maritalstatus": "married or partnered",
"note": "a 50 y.o. white, hispanic female was evaluated and diagnosed with glaucoma. needs PERSON, leaving town DATE_TIME",
"gpt4_summary": "50 y.o. white, Hispanic female diagnosed with glaucoma. Will be out of town at a specified date/time.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09539",
"image_path": "slo_fundus_09539.jpg",
"filename": "data_09539.npz",
"report": "63 y.o. female has Primary Open Angle Glaucoma (POAG) detected through c:d asymmetry and has a family history of glaucoma. Also noted is a mild non-visually significant cataract and refractive error.",
"age": 63.39,
"gender": "female",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "63 y.o. female 1. poag(s) based on c:d asymmetry od right eye [ fhx: no [ cct: 524,542 [ DATE_TIME: full od, suspicious for suptemp thinning os [ hvf DATE_TIME: superior defect ou (possible lid artifact) - superior visual field defect in both eyes. possible lid artifact but cannot rule out glaucomatous defect (though not concordant with area of thinning on oct). first-time testing. - plan for repeat visual field testing in the near future. rtc 3-4 months with hvf, sooner prn previously: # no evidence of diabetic retinopathy. - importance of blood glucose and blood pressure control discussed with patient. - annual dilated eye exams, sooner prn visual changes. # early dry age-related macular degeneration, both eyes. nonsmoker. no fhx. - monitor; discussed not smoking; uv protection; antioxidants. # refractive error, some change from previous, would like to update glasses. - new rx given to patient.",
"gpt4_summary": "73-year-old male patient with a history of hypertension and diabetes claimed floaters in right eye and underwent glaucoma testing. No retinal breaks found but showed increased cup/disc ratio which is indicative of glaucoma potential. No evidence of diabetic retinopathy. The patient also has early dry age-related macular degeneration in both eyes and a refractive error.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09553",
"image_path": "slo_fundus_09553.jpg",
"filename": "data_09553.npz",
"report": "Patient has narrow angles, CRT of 565/575, intraocular pressure is great in both eyes indicating no glaucoma. Also has stable hyperopia/presbyopia.",
"age": 68.01,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "1. narrow angles, ou. s/PERSON angle a little narrow od and more open os. cct 565/575. p dilation iop ou great ? 2. hyperopia/presbyopia - stable, continue with current mrx md at Institution sailor ? plan visual field borderline first test rnfl oct stable deferred dilation DATE_TIME intraocular pressure great both eyes rtc DATE_TIME for dilation both eyes & disc photos testing DATE_TIME",
"gpt4_summary": "Patient has narrow angles, CRT of 565/575, intraocular pressure is great in both eyes indicating no glaucoma. Also has stable hyperopia/presbyopia.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09557",
"image_path": "slo_fundus_09557.jpg",
"filename": "data_09557.npz",
"report": "57 y.o. female suspect for glaucoma presented for eye examination. Clinical findings revealed thin cct, superior thinning in both eyes, and superior arcuate defect. Also suffers from dry eye. Referred to glaucoma service.",
"age": 57.48,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "single",
"note": "57 y.o. female glaucoma suspect. presents for cee, 1. glaucoma suspect (c/d od>os) tmax DATE_TIME. cct 521/524 (thin). PERSON (mother, father) gonio: ciliary band body 360, with 2+ pigmenation on tm, no NRP ou (DATE_TIME) hvf DATE_TIME: PERSON, os with PERSON defects DATE_TIME: superotemporal thinning ou, od>os superiorly optic nerve photos 11/11 0.6/0.5 with intact rim ou oct: right eye reliability was good. left eye reliability was good. findings right eye superior thinning left eye superior was borderline. hvf: hvf mean deviation (os) - left eye -6.52 hvf mean deviation (od) - right eye -5.56 right eye reliability/fixation was borderline mean deviation was calculated to be: -5.56 db. interpretation of the testing revealed: superior arcuate defect left eye reliability/fixation was borderline. mean deviation was calculated to be: -6.52 db. interpretation of the testing revealed: superior arcuate defect 2.4. dry eye ou - instructed to apply warm compresses toclosed eyelids twice a day, for DATE_TIME at a time. - use over-the-counter artificial tears such as refresh, LOCATION, theratears 4 x per day or as needed. (systane sample given DATE_TIME) refer to glaucoma service",
"gpt4_summary": "57 y.o. female suspect for glaucoma presented for eye examination. Clinical findings revealed thin cct, superior thinning in both eyes, and superior arcuate defect. Also suffers from dry eye. Referred to glaucoma service.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09560",
"image_path": "slo_fundus_09560.jpg",
"filename": "data_09560.npz",
"report": "Patient underwent retinal detachment & cataract surgery and has history of uveitis due to ankylosing spondylitis; now stable. Glaucoma suspected due to optic cupping.",
"age": 70.85,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "unknown",
"note": "imp: s/p rd repair od s/p right phaco/iol and yag pc cataract os history of uveitis ou (ankylosing spondylitis); quiet lately drusen ou pvd os cupping ou; susp for glaucoma. cct 503/496; hvf full, oct PERSON; iop 16/16 DATE_TIME refr error --enjoys monovision plan: continue NRP yearly and repeat hvf and oct of rnfl and PERSON",
"gpt4_summary": "Patient underwent retinal detachment & cataract surgery and has history of uveitis due to ankylosing spondylitis; now stable. Glaucoma suspected due to optic cupping.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09561",
"image_path": "slo_fundus_09561.jpg",
"filename": "data_09561.npz",
"report": "The patient has nuclear sclerosis in both eyes, right exotropia with amblyopia, undergone strabismus surgery, has a pituitary lesion which was removed endoscopically, and thinning retinal nerve fiber layer in left eye. No glaucoma is indicated.",
"age": 71.51,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "imp: no diabetic retinopathy nuclear sclerosis ou right exotropia with amblyopia; s/p strabismus surgery pituitary lesion s/p endoscopic resection DATE_TIME cupping os (no hx iop elevation) --cct DATE_TIME; normal hvf os; temp rnfl thinning os; Normal rnfl od;; few paracentral and inferior losses od with poor fixation (NRP) refr error plan: yrly with repeat hvf and oct wang pgy4 i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow. i have reviewed the resident/fellow's notes and made any necessary changes. requests strabismus consult re large angle exotropia od",
"gpt4_summary": "The patient has nuclear sclerosis in both eyes, right exotropia with amblyopia, undergone strabismus surgery, has a pituitary lesion which was removed endoscopically, and thinning retinal nerve fiber layer in left eye. No glaucoma is indicated.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09562",
"image_path": "slo_fundus_09562.jpg",
"filename": "data_09562.npz",
"report": "34 y.o male diagnosed with glaucoma. Has life-long ocular albinism, limited peripheral vision, depth perception, and low light difficulties. Will consult with Dr. Comander.",
"age": 34.01,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "a 34 y.o. white, non-hispanic male was evaluated and diagnosed with glaucoma. imp: life-long hx of ocular albinism ---now c/o limited peripheral vision, depth perception, and low light difficulties hvf with central island ou; abn oct of rnfl and PERSON has LOCATION nystagmus on lateral gaze; largely resolves in primary NRP error plan: consult with dr. comander",
"gpt4_summary": "34 y.o male diagnosed with glaucoma. Has life-long ocular albinism, limited peripheral vision, depth perception, and low light difficulties. Will consult with Dr. Comander.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09564",
"image_path": "slo_fundus_09564.jpg",
"filename": "data_09564.npz",
"report": "The patient has been using brimonidine for left eye and has had various tests including dilation, RNFL, visual field, and disc photos. They are due for a follow-up in a glaucoma clinic.",
"age": 55.95,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "brimonidine bid os last dilated exam: DATE_TIME DATE_TIME rnfl: DATE_TIME last visual field: DATE_TIME baseline disc photos: DATE_TIME return to glaucoma clinic in DATE_TIME with dfe, and repeat optical coherence tomography and humphrey visual field 10-2 left eye only please",
"gpt4_summary": "The patient has been using brimonidine for left eye and has had various tests including dilation, RNFL, visual field, and disc photos. They are due for a follow-up in a glaucoma clinic.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09570",
"image_path": "slo_fundus_09570.jpg",
"filename": "data_09570.npz",
"report": "Suspected genetic optic atrophy, despite negative genet testing. Recent iritis improved with prednisolone. No mention of glaucoma. Plan includes research level testing and follow-up.",
"age": 28.96,
"gender": "male",
"race": "white",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "single",
"note": "mutations for optic atrophy has returned negative. as mentioned by PERSON, the genetics counselor who has worked with him, genet testing identifies a known genetic mutation about 50% of the time when there is a clinical diagnosis of genetic optic atrophy. it remains likely therefore that he has a form of DOA, perhaps with a mutation in a non-coding segment of dna. his examination DATE_TIME remains stable. he recently had iritis, but it currently is improved with prednisolone eye drops. he will follow the guidance of his ophthalmologist, but if there is any recurrence he can be referred to the uveitis service here. i will inquire whether there is any research testing that may be an option and will plan to see him in follow up in DATE_TIME. recommendations: 1. return in DATE_TIME. will inquire about research level testing ? PERSON, LOCATION ? note: greater than half of this DATE_TIME visit was spent counseling the patient on the medical condition or coordinating care.",
"gpt4_summary": "Suspected genetic optic atrophy, despite negative genet testing. Recent iritis improved with prednisolone. No mention of glaucoma. Plan includes research level testing and follow-up.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09573",
"image_path": "slo_fundus_09573.jpg",
"filename": "data_09573.npz",
"report": "79-year-old female evaluated for glaucoma. She has a family history of glaucoma (mother). Tests show likely physiologic cupping, thin cornea but glaucoma risk is very low. Regular eye exams are suggested.",
"age": 79.88,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "79 y.o. female patient presents for cataract followup former neonatologist at bwh \u00ff referred by dr. PERSON for glaucoma eval # most likely physiologic cupping ou +fhx for glaucoma (mother on drops) large nerves cct thin, 506/508 on lenstar tmax 17, DATE_TIME (tonopen) in cornea clinic tcurrent 11,10 hvf full oct wnl ou rims appear intact clinically d/w patient this is most likely physiologic cupping given her reassuring testing. she does have risk factors of thin cornea and mother who is on drops (but unknown glaucoma status), however her clinical appearance is very reassuring overall. recommend DATE_TIME dilated eye exams to ensure no new suspicious changes, but at this point the risk of glaucoma appears very low. #s/p PERSONIME (zxr00 +20.5 diopters, aim -0.25) - mrx: -0.75 - 0.25 x049 \u00ff # s/p ceiol os DATE_TIME (zxr00 +21.5\u00ffdiopters, aim -0.50) - patient very happy with results mrx: -0.50 -0.50 x058 \u00ff \u00ff # s/p bll ectropion repair DATE_TIME (dr. PERSON) lower lid laxity with tearing ou not interested in pursuing surgery # history of bcc on face, lip, nasal canthus od, forehead # chalazion lll expressed PERSON at slit lamp with gentle pressure on lid no ulceration or bleeding, no madarosis start wc rec plastics if not improved plan recommend routine DATE_TIME eye exams return to glaucoma clinic with any concerns",
"gpt4_summary": "79-year-old female evaluated for glaucoma. She has a family history of glaucoma (mother). Tests show likely physiologic cupping, thin cornea but glaucoma risk is very low. Regular eye exams are suggested.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09575",
"image_path": "slo_fundus_09575.jpg",
"filename": "data_09575.npz",
"report": "The patient has elevated igm anticardiolipin antibody and congenital color deficiency. No mention of glaucoma. The patient got nauseous during dye testing.\n\n",
"age": 46.47,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "anticardiolipin antibody after DATE_TIME because the igm anticardiolipin antibody might appear transiently. 3. congenital color deficiency recommendations. 1. patient will discuss the elevated igm anticardiolipin antibody with dr. mark 2. return prn 3. DATE_TIME general eye exam PERSON, PERSON, neuro-ophthalmology service i spent a total of greater than (DATE_TIME preparing and caring for this patient (face-to-face and non face-to-face); formulating and finalizing the note.] pt states that gets very nauseous with any kind of dye testing. this nurse verified that pt did not have any shellfish allergy dye to iodine in the dye. icg dye warmed for pt to reduce chance of nausea. icg administered via butterfly to r antecub. DATE_TIME after injection, pt began throwing up. throwing up resolved after DATE_TIME and with sniffing alcohol swap. testing was stopped for DATE_TIME due to throwing up. pt able to leave testing without any distress. shari PERSON, PERSON neuro-ophthalmology LOCATION PHONE_NUMBER fax PHONE_NUMBER",
"gpt4_summary": "The patient has elevated igm anticardiolipin antibody and congenital color deficiency. No mention of glaucoma. The patient got nauseous during dye testing.\n\n",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09576",
"image_path": "slo_fundus_09576.jpg",
"filename": "data_09576.npz",
"report": "The 85-year-old male patient, an ex-mathematician now working for Wolfram, has primary open-angle glaucoma. It is at an advanced stage in the right eye and mild stage in the left. He also has pseudophakia, wet age-related macular degeneration, dry eye syndrome, and ocular surface disease.",
"age": 85.06,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "85 y.o. m prev pt of PERSON former mathematician, now 'telecommutes' for wolfram in PERSON, still works DATE_TIME / day! doing well. wife got a job at google. \u00ff # primary open angle glaucoma ou, advanced stage od/mild stage os - diagnosis: DATE_TIME, was followed in LOCATION and states his doctor noted his iop was trending upward - h/o slt od 4/16 - cct 570s/580s - tmax 46 od, ?28os - rnfl oct shows diffuse thinning od, full os \u00ff - iop goal low-teens od, mid/high teens os - at goal \u00ff\u00ff # pseudophakia ou - stable ou \u00ff\u00ff # age-related macular degeneration, wet, ou - followed by dr. PERSON, s/p multiple anti-vegf injections most recently DATE_TIME ou \u00ff\u00ff # dry eye syndrome ou in setting of ectropion and incomplete lid closure od: - seeing dr. PERSON, add wc/lh bid, pt having mixed results with tears continue to try \u00ff # ocular surface disease - component of medicamentosa. much improved since switching to pf cosopt - continue lid scrubs and wc - in future can consider switch to LOCATION, anticipate pa \u00ff\u00ff plan \u00ffdoing well with current regimen, surface looks great cont cosopt-pf bid ou cont PERSON qhs ou --> hold off on switch to zioptan qhs ou - patient may change insurance now that wife is hired by google holding PERSON bid \u00ff continue genteal gel qhs ou \u00ff DATE_TIME iop, dilate, oct rnfl gcc and dp",
"gpt4_summary": "The 85-year-old male patient, an ex-mathematician now working for Wolfram, has primary open-angle glaucoma. It is at an advanced stage in the right eye and mild stage in the left. He also has pseudophakia, wet age-related macular degeneration, dry eye syndrome, and ocular surface disease.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09579",
"image_path": "slo_fundus_09579.jpg",
"filename": "data_09579.npz",
"report": "Patient has mild uveitic glaucoma in the right eye and is a glaucoma suspect in the left due to cup to disc ratio. She's had past treatments for iris bombe and responses to steroids.",
"age": 32.09,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "first seen by dr. PERSON on DATE_TIME glaucoma medication intolerances: none target iop: DATE_TIME, tmax: unknown / unknown central corneal thickness: 534 / 548 gonioscopy: PERSON 1+ ou, with broad pigmentation/iris processes od retinal nerve fiber layer, right eye: no focal thinning, globally slightly thinner than os retinal nerve fiber layer, left eye: no thinning visual fields, right eye: essentially full, watch for superior arcuate visual fields, left eye: full family history: none steroids: topical, sub-tenon's trauma: none asthma/copd: none other medical history and problems: hla-b27-related spondyloarthritis, migraine assessment/plan: 32 y.o. female PERSON post-doc in analytical chemistry # uveitic glaucoma, mild, right eye # glaucoma suspect due to cup to disc ratio, left eye - s/p laser peripheral iridotomy od (2008), surgical iridectomy od (DATE_TIME) for iris bombe - history of steroid response to sub-tenon's triamcinolone that was controlled with simbrinza - iop acceptable ou, oct and vf roughly stable ou, though watch for superior arcuate od - continue to monitor without resuming treatment - return in DATE_TIME for iop check # hla-b27 associated anterior uveitis, right eye - diagnosed at age 14 - off LOCATION and topical steroids - next appointment with PERSON butler DATE_TIME # s/p cataract surgery with posterior chamber intraocular lens, right eye (DATE_TIME) - monitor # soft contact lens wear, left eye - monitor PERSON, PERSON___________________ i saw and evaluated this patient and discussed the case as appropriate with the resident. i have reviewed the resident's notes and made any necessary changes. PERSON scribing for dr. PERSON i attest that i was present while this encounter was recorded and agree that the information entered by my scribe and updated by me is complete and accurate. PERSON, md",
"gpt4_summary": "Patient has mild uveitic glaucoma in the right eye and is a glaucoma suspect in the left due to cup to disc ratio. She's had past treatments for iris bombe and responses to steroids.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09583",
"image_path": "slo_fundus_09583.jpg",
"filename": "data_09583.npz",
"report": "Patient has severe pseudoexfoliation glaucoma in right eye, glaucoma suspected due to cup to disc ratio in left eye. Intolerant to certain glaucoma medications. Retinal nerve fiber thinning in the right eye. Controlled intraocular pressure, declined selective laser trabeculoplasty and trabeculectomy. Also has mild, not significant pterygium in left eye and cataract in both eyes.",
"age": 57.93,
"gender": "male",
"race": "white",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "married or partnered",
"note": "first seen by dr. PERSON on DATE_TIME (previously followed by dr. PERSON) glaucoma medication intolerances: bak (allergy, blepharodermatitis); Alphagan P (injection); acetazolamide/methazolamide (tingling in hands/feet/face, polyuria) target iop: 16 / 22, tmax: 45 / 22 central corneal thickness: 540 / 555 gonioscopy: od: (c)d35b 4+; os: d40f 4+ retinal nerve fiber layer, right eye: superior/inferior thinning retinal nerve fiber layer, left eye: no thinning visual fields, right eye: superior arcuate, inferior nasal step into arcuate visual fields, left eye: grossly full family history: none steroids: none trauma: none asthma/copd: none other medical history and problems: hld assessment/plan: 57 y.o. male bar owner, landscaping company owner # pseudoexfoliation glaucoma, severe, right eye # glaucoma suspect due to cup to disc ratio, left eye - s/p micropulse cpc/gatt od (DATE_TIME) - extremely rapid progression in DATE_TIME but not as quickly as expected in DATE_TIME while iop uncontrolled, patient previously had been hesitant to travel to see glaucoma specialist, had declined selective laser trabeculoplasty, also developed severe drop allergies - iop acceptable ou - had declined trabeculectomy od when iop previously much higher - oct ou and vf os roughly stable, vf od unreliable - continue zioptan qhs od, cosopt pf bid od - return in DATE_TIME for iop check - gave patient contact information for dr. PERSON office because he lives in LOCATION; patient also considering moving to LOCATION # pterygium, left eye - mild, not visually significant, monitor # cataract, both eyes - mild, not visually significant, monitor PERSON scribing for dr. PERSON i attest that i was present while this encounter was recorded and agree that the information entered by my scribe and updated by me is complete and accurate. PERSON, md",
"gpt4_summary": "Patient has severe pseudoexfoliation glaucoma in right eye, glaucoma suspected due to cup to disc ratio in left eye. Intolerant to certain glaucoma medications. Retinal nerve fiber thinning in the right eye. Controlled intraocular pressure, declined selective laser trabeculoplasty and trabeculectomy. Also has mild, not significant pterygium in left eye and cataract in both eyes.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09584",
"image_path": "slo_fundus_09584.jpg",
"filename": "data_09584.npz",
"report": "Patient has end-stage open angle glaucoma in left eye (OS) and mild primary open angle glaucoma in right eye (OD). Maternal uncle also had glaucoma. Possible history of eye trauma. Non-compliant with high pressures, needs increased monitoring.",
"age": 53.77,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "attendings a/p: - end-stage open angle glaucoma os, primary open angle glaucoma, mild od - maternal uncle with glaucoma - ? h/o eye trauma os hit with finger but didn't go to eye md - no past steroid use, tmax 32/32 os, cct 534/541 - was last seen by me DATE_TIME and then reported to er in interim DATE_TIME for lost to follow up and noncompliance with high pressures, lost to f/u again from DATE_TIME. - oct od worse in DATE_TIME. hx of iop elevation ou in DATE_TIME. - goal iop mid teens od, comfort os - iop at goal DATE_TIME ou. plan: c/w xal ou qhs, c/w cosopt ou tid, c/w alphagan ou tid - reinforced compliance. - may need cpc mp in the near future. - stressed compliance - rtc in DATE_TIME for iop check ou and dfe ou. - monocular precautions; polycarbonate (impact resistant) prescription given in DATE_TIME - other: seen by dr. PERSON and dr. PERSON. hx of car accident in DATE_TIME. guy PERSON scribing for dr. PERSON (DATE_TIME, 4:08 pm) i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "Patient has end-stage open angle glaucoma in left eye (OS) and mild primary open angle glaucoma in right eye (OD). Maternal uncle also had glaucoma. Possible history of eye trauma. Non-compliant with high pressures, needs increased monitoring.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09587",
"image_path": "slo_fundus_09587.jpg",
"filename": "data_09587.npz",
"report": "Patient had prior BRVO in right eye, laser treated cataract in both eyes, suspected glaucoma. On Timolol and Xalatan. Eye pressure stable, but there is increasing retinal nerve fiber layer thinning and visual field loss. Further glaucoma consultation needed.",
"age": 75.72,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "imp: s/p brvo od; PERSON and laser prev cataract ou glaucoma suspect ou; on timolol and xalatan; iop stable, but progression of rnfl thinning od and hvf ou refr error plan: cpm for now consult with glaucoma service",
"gpt4_summary": "Patient had prior BRVO in right eye, laser treated cataract in both eyes, suspected glaucoma. On Timolol and Xalatan. Eye pressure stable, but there is increasing retinal nerve fiber layer thinning and visual field loss. Further glaucoma consultation needed.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09588",
"image_path": "slo_fundus_09588.jpg",
"filename": "data_09588.npz",
"report": "73 y.o. female is a glaucoma suspect with enlarged c/d od>os, thinning ou, open gonio, and a history of retinal tear. Stable >rd precautions, mild blepharitis, and refractive error noted.",
"age": 73.72,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "assessment and plan 73 y.o. female glaucoma suspect: enlarged c/d od>os -incr c/d -famhx neg -tprev: 17/15, 18/18, 19/20 -tcurrent: 14/14 -pachy : 544/551 -oct DATE_TIME: thinning ou -oct DATE_TIME: od sup and PERSON thinning; os sup thinning; stable ou -oct DATE_TIME: od inf thinning; PERSON; stable ou -hvf DATE_TIME: full ou -hvf DATE_TIME: PERSON DATE_TIME: full ou, no bs plotted -gonio: open ou -disc photos DATE_TIME h/o retinal tear s/p laser os -stable >rd precuations blepharitis -mild, may have had recent flare up DATE_TIME that improved with emycin ung >warm compresses and lid hygiene bid >at qid prn s/p phaco/pciol os DATE_TIME; s/p phaco/PERSONIME -doing well refractive error >mrx given at patient's request f/u 1 yr: hvf, oct nerve",
"gpt4_summary": "73 y.o. female is a glaucoma suspect with enlarged c/d od>os, thinning ou, open gonio, and a history of retinal tear. Stable >rd precautions, mild blepharitis, and refractive error noted.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09589",
"image_path": "slo_fundus_09589.jpg",
"filename": "data_09589.npz",
"report": "68-year-old Hispanic male with no diagnosed glaucoma. Prescreening completed.",
"age": 68.08,
"gender": "male",
"race": "white",
"ethnicity": "hispanic",
"language": "spanish",
"maritalstatus": "married or partnered",
"note": "a 68 y.o. white, hispanic male with no diagnosis of glaucoma. prescreen complete",
"gpt4_summary": "68-year-old Hispanic male with no diagnosed glaucoma. Prescreening completed.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09590",
"image_path": "slo_fundus_09590.jpg",
"filename": "data_09590.npz",
"report": "Patient has advanced-stage primary open-angle glaucoma (POAG) with intraocular pressure (IOP) close to target but not ideal. Visual field tests stable. Undergone 'trabectome' glaucoma procedures. Possible allergies to some meds. IOP increased again.",
"age": 78.15,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "1. poag advanced stage with gon ou tmax 20mmhg ou, cct 500/491 microns - iop now close to target but not ideal, ou. it is encouraging that vfs have been stable since DATE_TIME glaucoma procedures: od: LOCATION; \u00fftrabectome. \u00ff os: LOCATION; trabectome glaucoma medication issues: alphagan allergy; probable bak allergy but tolerating PERSON; prostaglandin associated periorbitopathy\u00ff \u00ff\u00ff\u00ff\u00ff\u00ff\u00ff+ asthma \u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00fftarget<14 ?? 2. pds - \u00ffpt was told that she had this diagnosis at DATE_TIME. pseudophakia ou \u00ff plan: ?iop\u00fftoo high DATE_TIME and eyes red continue PERSON \u00ffand\u00ffvyzulta qhs os- iop increased to 21, 20 w/o rhopressa added xalatan ou with initial good response (13 both eyes) but now intraocular pressure back up to 20 right eye and 19 left eye- however, her daughter says that she just moved into assisted living DATE_TIME and that she may be out of her routine cpm rv DATE_TIME iop check NRP \u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff",
"gpt4_summary": "Patient has advanced-stage primary open-angle glaucoma (POAG) with intraocular pressure (IOP) close to target but not ideal. Visual field tests stable. Undergone 'trabectome' glaucoma procedures. Possible allergies to some meds. IOP increased again.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09593",
"image_path": "slo_fundus_09593.jpg",
"filename": "data_09593.npz",
"report": "Patient has presbyopia and dry eye syndrome, experiencing worsening intermittent blurry vision. Over the counter readers not helping. Suspected dry eye suggested, glaucoma not mentioned.",
"age": 83.36,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "presbyopia # dry eye syndrome - has been having worsening intermittent blurry vision when reading - has been using +2.50 d over the counter readers without improvement. could increase to +3d and increase illumination - suspect possible dry eye component given improvement with blinking - recommend artificial tears - to optometry to new refraction for reading only.",
"gpt4_summary": "Patient has presbyopia and dry eye syndrome, experiencing worsening intermittent blurry vision. Over the counter readers not helping. Suspected dry eye suggested, glaucoma not mentioned.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09596",
"image_path": "slo_fundus_09596.jpg",
"filename": "data_09596.npz",
"report": "Patient has primary open angle glaucoma (POAG), stable intraocular pressure. On Xalatan and Timolol. Presence of cataract and posterior vitreous detachment. No diabetic retinopathy.",
"age": 76.79,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "imp: 1. poag; stable iop, on xalatan and timolol ou; tmax 24.5/24; 560/563; oct/hvf with progression DATE_TIME. cataract ou 3. pvd (floater) ou 4. no diabetic retinopathy 5. refr error plan: cpm consult glaucoma service",
"gpt4_summary": "Patient has primary open angle glaucoma (POAG), stable intraocular pressure. On Xalatan and Timolol. Presence of cataract and posterior vitreous detachment. No diabetic retinopathy.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09599",
"image_path": "slo_fundus_09599.jpg",
"filename": "data_09599.npz",
"report": "Patient prescribed brimonidine/alphagan3 and brinzolamide/azopt for the left eye 3x/day. Contact glaucoma department with questions. EM contact: glaucoma physician on-call.",
"age": 78.95,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "medication route frequency brimonidine/alphagan3 (purple) the left eye 3x/day brinzolamide/azopt (orange)& the left eye 3x/day 3 some medications that may be prescribed in lieu of this medication include: brimonidine, alphagan, PERSON some medications that may be prescribed in lieu of this medication include: dorzolamide, trusopt, PERSON, brinzolamide. always wait DATE_TIME (by the clock) in between eye drops. please bring this to your next visit. for routine questions, please call PHONE_NUMBER (LOCATION, ask for glaucoma department) or PHONE_NUMBER (longwood). you can also reach dr. PERSON 's administrative assistant at (617)-573 for emergencies, please call PHONE_NUMBER and ask for the glaucoma physician on-call.",
"gpt4_summary": "Patient prescribed brimonidine/alphagan3 and brinzolamide/azopt for the left eye 3x/day. Contact glaucoma department with questions. EM contact: glaucoma physician on-call.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09600",
"image_path": "slo_fundus_09600.jpg",
"filename": "data_09600.npz",
"report": "24-year-old white, Hispanic male diagnosed with glaucoma. Examined by PERSON MD, PhD in ophthalmology.",
"age": 24.76,
"gender": "male",
"race": "white",
"ethnicity": "hispanic",
"language": "english",
"maritalstatus": "single",
"note": "a 24 y.o. white, hispanic male was evaluated and diagnosed with glaucoma. hours. Attending to Review: PERSON PERDSON MD, PhD Ophthalmology Residen LOCATION PERSON Resident DATE_TIME PERSON, MD DATE_TIME",
"gpt4_summary": "24-year-old white, Hispanic male diagnosed with glaucoma. Examined by PERSON MD, PhD in ophthalmology.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09602",
"image_path": "slo_fundus_09602.jpg",
"filename": "data_09602.npz",
"report": "Patient has keratoconus, previous pkp od, rgp os, pvd od, cataract os, pseudophakia od, and a chiasmal tumor which is stable on cabergoline. No presence of glaucoma.",
"age": 58.42,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "imp keratoconus ou- sp pkp od (prev followed by PERSON PERSON), rgp os pvd od cataract os pseudophakia od chiasmal tumor- LOCATION stable on cabergoline (last mri DATE_TIME). last seen by dr. PERSON neuro-op DATE_TIME. no new symptoms but sent by Institution neuro-endocrine to update hvf and for comprehensive exam. hvf with temporal defects od and diffuse suppression os with high fl. oct borderline od and thin os (most prom sup and PERSON). similar pattern compared to notes from DATE_TIME plan: oct/hvf non glaucomatous and PERSON, f/u neuro-op non urgent for ongoing hvf f/u dr. PERSON for rgp update monitor cataract and keratoconus- re-refer to cornea when needed i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow. i have reviewed the resident/fellow's notes and made any necessary changes. management by neuro-oph, cornea, and optom services",
"gpt4_summary": "Patient has keratoconus, previous pkp od, rgp os, pvd od, cataract os, pseudophakia od, and a chiasmal tumor which is stable on cabergoline. No presence of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09603",
"image_path": "slo_fundus_09603.jpg",
"filename": "data_09603.npz",
"report": "The patient is prepping for surgery, taking chlorhexidine, hydrochlorothiazide, and losartan. Skin conditions involve basal cell carcinoma and squamous cell carcinoma. No mention of glaucoma.",
"age": 75.25,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "chlorhexidine (hibiclens) 4 % external liquid apply topically DATE_TIME. wash lower legs qd DATE_TIME prior to surgery PERSON DATE_TIME metal med transfer process hydrochlorothiazide (hydrodiuril) 25 mg tablet take 1 tablet by mouth DATE_TIME. PERSON DATE_TIME metal med transfer process losartan (cozaar) 50 mg tablet take 1 tablet by mouth DATE_TIME. PERSON DATE_TIME metal med transfer process your orders future appointments provider department dept phone DATE_TIME a LOCATION, PERSON physicians & surgeons UK_NHS DATE_TIME DATE_TIME PERSON, PERSONtitution neuro oph main campus PHONE_NUMBER future orders complete by expires ophthalmology research imaging as directed DATE_TIME orders placed this visit fundus photos - ou - both eyes humphrey visual field - ou - both eyes oct, optic nerve - ou - both eyes - cirrus; rnfl, gcc; no condition list as of DATE_TIME hypertensive disorder nephritis skin lesion basal cell carcinoma of back basal cell carcinoma of skin of scapular region superficial basal cell carcinoma of skin of left shoulder basal cell carcinoma of scapular region basal cell carcinoma of scapular region neoplasm of uncertain behavior of skin squamous cell carcinoma of left upper extremity basal cell carcinoma of right forehead basal cell carcinoma of sideburn area results summary immunizations administered on date of encounter - DATE_TIME none",
"gpt4_summary": "The patient is prepping for surgery, taking chlorhexidine, hydrochlorothiazide, and losartan. Skin conditions involve basal cell carcinoma and squamous cell carcinoma. No mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09604",
"image_path": "slo_fundus_09604.jpg",
"filename": "data_09604.npz",
"report": "The note discusses test review, independent interpretation of tests, and communication regarding patient management. The patient shows a potential high risk of visual/neurological issues. No mention of glaucoma.",
"age": 42.07,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "also included review of the following data: 1) results of tests and outside documents; review of unique test results (including those described under 'ancillary studies' above); ordering unique tests); 2) independent interpretation of tests performed by dr. PERSON, LOCATION; and 3) discussion or communication of management with dr. PERSON. with respect to management, this patient has a potentially high risk of visual or neurological morbidity related to the above diagnoses and considerations of management.] PERSON, PERSON neuro-ophthalmology LOCATION PHONE_NUMBER fax PHONE_NUMBER",
"gpt4_summary": "The note discusses test review, independent interpretation of tests, and communication regarding patient management. The patient shows a potential high risk of visual/neurological issues. No mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09605",
"image_path": "slo_fundus_09605.jpg",
"filename": "data_09605.npz",
"report": "The patient has open-angle glaucoma which has responded well to latanoprost. Other risk factors include diabetes and race. The observed intraocular pressure was 17/20. The patient also has hyperopia with astigmatism, presbyopia, and has begun insulin for diabetes management. Hemoglobin A1c levels are high.",
"age": 65.4,
"gender": "female",
"race": "black",
"ethnicity": "unknown",
"language": "unknown",
"maritalstatus": "divorced",
"note": "oag very good response to latanoprost risks include dm, race, PERSON (brother in drops), optic nerve appearance iop is 17/20, PERSON is +5 ou. PERSON ou hvf--nonspecific changes cpm with PERSON pciol os stable. done at LOCATION. combined forms of cataract od iol master done observation recommended at this time. no trouble with day or DATE_TIME driving. pinguecula ou hx of pterygium removal os reports tearing od>>os. use at's prn, uv protection. hyperopia with astigmatism and presbyopia new rx given to pt. PERSON. PERSON diagnosed DATE_TIME. recently started insulin, also on oral meds. spoke about the importance of blood sugar control. hgb a1c date value ref range status DATE_TIME 7.5 (h) 4.2 - 5.6 % final comment: hba1c levels 5.7-6.4% represent pre-diabetes, indicating impaired glucose control and an increased risk of developing diabetes. the diagnostic hba1c level for diabetes is 6.5% or greater. hba1c levels <4.2% may indicate a hemoglobinopathy or anemia, and an alternative method is recommended to monitor glucose control. hemoglobin a1c date value ref range status DATE_TIME 8.1 (h) 4.2 - 5.6 % final comment: hba1c levels 5.7-6.4% represent pre-diabetes, indicating impaired glucose control and an increased risk of developing diabetes. the diagnostic hba1c level for diabetes is 6.5% or greater. hba1c is performed by the roche tina-quant immunoassay method which does not detect (incidental) hemoglobin variants. hemoglobin electrophoresis should be ordered in patients with suspected hemoglobinopathies. f/u in DATE_TIME iop check with icare, hvf 24-2, no dilation",
"gpt4_summary": "The patient has open-angle glaucoma which has responded well to latanoprost. Other risk factors include diabetes and race. The observed intraocular pressure was 17/20. The patient also has hyperopia with astigmatism, presbyopia, and has begun insulin for diabetes management. Hemoglobin A1c levels are high.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09609",
"image_path": "slo_fundus_09609.jpg",
"filename": "data_09609.npz",
"report": "The patient has stable chronic illnesses and is at a moderate risk of glaucoma progression without care. She has good IOP control, is on a regimen of Brimonidine BID OS, and uses preservative-free artificial tears.",
"age": 60.49,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "pressure less than or equal to 20 mmhg, left eye. -iop at goal od and at goal os on DATE_TIME on brimonidine bid os. -continue brimonidine bid os. -instructions written/typed/printed out for patient (see table/details under patient instructions) previously. -emphasized adherence to medication regimen. -preservative-free artificial tears as needed. -long discussion with patient on DATE_TIME: given stable chronic illnesses with good iop control, we will continue monitoring the patient on the prescription drug regimen described above. importance of follow-up explained to patient given moderate risk of progression without care. i assured her that the ora pressures are not always accurate and my iop measurements are what matter most. i also checked the cyst on her left eye, which does not appear worrisome upon exam. i also explained the importance of utilizing preservative-free artificial tears every DATE_TIME while staring at screens or reading for prolonged periods of time. -rtc in DATE_TIME with iop check ou, hvf os, and disc photos ou, sooner prn. the information above was documented by Person as a scribe for PERSON on DATE_TIME. i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate. i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow (PERSON, md). i have reviewed the resident/fellow's notes and made any necessary changes. i saw and evaluated this patient and discussed the case as appropriate with the medical student (PERSON).",
"gpt4_summary": "The patient has stable chronic illnesses and is at a moderate risk of glaucoma progression without care. She has good IOP control, is on a regimen of Brimonidine BID OS, and uses preservative-free artificial tears.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09610",
"image_path": "slo_fundus_09610.jpg",
"filename": "data_09610.npz",
"report": "The patient chose to proceed with laser trabeculoplasty, a treatment for glaucoma, despite the risk of prolonged inflammation and acute eye pressure elevation. He also has mild, visually insignificant cataract in both eyes.",
"age": 62.32,
"gender": "male",
"race": "white",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "married or partnered",
"note": "discussed the risks/benefits/alternative of laser trabeculoplasty including but not limited to the following: prolonged inflammation, and acute eye pressure elevation. after this discussion, the patient elected to proceed. - continue latanoprost once nightly both eyes \u00ff # cataract, both eyes - mild, not visually significant, monitor \u00ff i, PERSON, am acting as scribe for PERSONmd, PERSON for patient vincent j cardillo on DATE_TIME. - PERSON",
"gpt4_summary": "The patient chose to proceed with laser trabeculoplasty, a treatment for glaucoma, despite the risk of prolonged inflammation and acute eye pressure elevation. He also has mild, visually insignificant cataract in both eyes.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09612",
"image_path": "slo_fundus_09612.jpg",
"filename": "data_09612.npz",
"report": "The patient has visual symptoms of multiple sclerosis including diplopia, vision loss, and visual field loss. They also have psoriatic arthritis. No mention of glaucoma.",
"age": 16.94,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "visual symptoms that ms can cause, including diplopia, vision loss from optic neurits and visual field loss and recommended that she calls me if any of these symptoms develop. she should follow with dr. NRP for initiation of dmt as scheduled. ? impression: 1. left ino - resolved 2. recent diagnosis of multiple sclerosis 3. psoriatic arthritis ? recommendations: 1. oct with rnfl/gcl DATE_TIME and macular cube 2. follow up in DATE_TIME with repeat visual fields 3. follow with PERSON NRP for initiation of dmt as scheduled it is a pleasure to participate in the care of this patient. please do not hesitate to call with questions. ? sincerely, ? PERSON, LOCATION note was prepared with the assistance of dr. PERSON, neuro-ophthalmology fellow. i spent DATE_TIME with this patient, more than 50% of which was face to face with the patient.",
"gpt4_summary": "The patient has visual symptoms of multiple sclerosis including diplopia, vision loss, and visual field loss. They also have psoriatic arthritis. No mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09613",
"image_path": "slo_fundus_09613.jpg",
"filename": "data_09613.npz",
"report": "The patient has no thinning of optic nerve RNFL, GCC. No optic disc drusen or hyperaf is present. Examination results led to low suspicion for iih, so no imaging needed.",
"age": 31.73,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "rapd, optic nerves with lumpy nasal elevation -efferent exam normal: full eom hvf 24-2 ou: full ou oct optic nerve rnfl, gcc: no thinning ou faf ou: no optic disc hyperaf suggestive of optic disc drusen ou b scan ou: no acoustic evidence of optic disc drusen ou case discussed with neuro-op on call (stevanovic) given reassuring afferent exam and minimal findings, very low suspicion for iih, no indication for imaging at this time plan: -referral to cos within DATE_TIME -return precautions discussed extensively -return sooner with worsening pain, vision changes, other concerns d/w PERSON pgy2 PERSON, md, phd resident DATE_TIME 1403 PERSON LOCATION, NRPE 1620",
"gpt4_summary": "The patient has no thinning of optic nerve RNFL, GCC. No optic disc drusen or hyperaf is present. Examination results led to low suspicion for iih, so no imaging needed.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09615",
"image_path": "slo_fundus_09615.jpg",
"filename": "data_09615.npz",
"report": "59-year-old female with asthma, experiencing vitreous floaters, has normal rnfl and macular OCT tests but shows paracentral defects on hvf. Uncertainty on the cause hinted it might be due to cataracts. She has an operculated retinal hole or asymptomatic chorioretinal scars which are stable. She also has cataracts which are borderline significant at this point, causing slight myopic shift in her left eye. There's no mention of glaucoma.",
"age": 60.03,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "59 y.o. woman with asthma followed by dr. PERSON and PERSON previously, requesting f/u here in 243 inferior drance heme od (noted DATE_TIME) - noted in ew, not seen DATE_TIME - hvf DATE_TIME borderline reliable due to high fl/ fn od paracentral defects os paracentral defects DATE_TIME unreliable due to high fl/ fn od paracentral defects os paracentral defects DATE_TIME od nasal paracentral defects os nasal defects DATE_TIME od inf and superior nasal defects increased from prior PERSON and sup nasal defects increased from DATE_TIME DATE_TIME wnl ou DATE_TIME wnl ou DATE_TIME PERSON ou DATE_TIME nl ou - macular oct previously wnl ou > unclear reason for paracentral defects on hvf. rnfl oct and macular oct are both normal. may be affected by cataracts > observe operculated retinal hole ou, old chorioretinal scars ou - asymptomatic, stable to DATE_TIME other breaks with prior scleral depression 360 ?? vitreous floaters ou - retina intact cataracts ou, os>od - borderline visually signfiicant at this time with slight myopic shift os - pt wishes to observe for now > updated mrx given DATE_TIME ? dry eyes ou - in the past tried restasis bid ou (started 11/10) but gives her headache - related to nasal pinguecula and heat - use at qid episcleritis os noted DATE_TIME - resolved - also has pingueculae ou > artificial tears for comfort fu DATE_TIME, mrx, bat dilate i saw and evaluated this patient and discussed the case as appropriate with the resident. i have reviewed the resident's notes and made any necessary changes. PERSON",
"gpt4_summary": "59-year-old female with asthma, experiencing vitreous floaters, has normal rnfl and macular OCT tests but shows paracentral defects on hvf. Uncertainty on the cause hinted it might be due to cataracts. She has an operculated retinal hole or asymptomatic chorioretinal scars which are stable. She also has cataracts which are borderline significant at this point, causing slight myopic shift in her left eye. There's no mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09619",
"image_path": "slo_fundus_09619.jpg",
"filename": "data_09619.npz",
"report": "Patient referred as glaucoma suspect due to cupping and ohtn. Both eyes show full RNFL/GCIPL. Right eye shows some visual field defects. No record of glaucoma procedures or other eye issues. Patient has thick CCT and minimal visual issues.",
"age": 47.61,
"gender": "male",
"race": "white",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "married or partnered",
"note": "first seen by Person on DATE_TIME. referred by PERSON PERSON diagnosis: glaucoma suspect due to cupping and ohtn target iop: / , tmax: ( ) / ( ) central corneal thickness: 629 / 642 gonioscopy: cbb refractive error: od -PHONE_NUMBER / os -0.50 . -0.50 . 080 optic nerve/rnfl findings on initial visit right eye (DATE_TIME): full rnfl, artifact nasally and on gcipl optic nerve/rnfl findings on initial visit left eye (DATE_TIME): full rnfl/gcipl visual fields on initial visit right eye (DATE_TIME): few scattered defects visual fields on initial visit left eye (DATE_TIME): full medication history at first visit: medication intolerances: glaucoma procedures right eye: glaucoma procedures left eye: other eye procedures right eye: other eye procedures left eye: other eye problems right eye: other eye problems left eye: family history: no steroids: no trauma: no asthma: no other medical history and problems: assessment: 1. glaucoma suspect, low risk ou -thick cct, not relaxed during iop check; was normal when i checked -oct with artifact, need to dilate next visit and repeat DATE_TIME and iop's normal, can follow back with dr. PERSON 2. history of esotropia s/p strabismus surgery -used patching and glasses as a kid -doing well, no double vision 3. latent nystagmus ou -see above plan: -monitor off of iop medications rtc in DATE_TIME for LOCATION, oct rnfl/gcipl (wait until fully dilated, poor scan)",
"gpt4_summary": "Patient referred as glaucoma suspect due to cupping and ohtn. Both eyes show full RNFL/GCIPL. Right eye shows some visual field defects. No record of glaucoma procedures or other eye issues. Patient has thick CCT and minimal visual issues.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09622",
"image_path": "slo_fundus_09622.jpg",
"filename": "data_09622.npz",
"report": "Patient has dry eyes and nuclear sclerosis in both eyes. No diabetic retinopathy. More cupping in left eye than right. Normal IOP, HVF, OCT RNFL. No glaucoma.",
"age": 50.62,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "imp: dry ou no diabetic retinopathy cupping os>od - iop nl, PERSON, hvf and oct rnfl nl nuclear sclerosis ou refr error plan: art tears yrly repeat hvf and oct of rnfl then",
"gpt4_summary": "Patient has dry eyes and nuclear sclerosis in both eyes. No diabetic retinopathy. More cupping in left eye than right. Normal IOP, HVF, OCT RNFL. No glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09623",
"image_path": "slo_fundus_09623.jpg",
"filename": "data_09623.npz",
"report": "The patient is using latanoprost ophthalmic solution for eyes nightly, suggesting a likely treatment for glaucoma. Other conditions include rosacea, ankle sprain, syncope, migraine, atrial fibrillation, and hypertrophic cardiomyopathy.",
"age": 39.94,
"gender": "female",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "latanoprost (xalatan) 0.005 % ophthalmic solution place 1 drop into each eye nightly. oxazepam (PERSON) 10 mg capsule take 10 mg by mouth DATE_TIME. reported on DATE_TIME nikhil arun sangave DATE_TIME 1:19 pm received from: partners lmr received sig: oxazepam 10 mg capsule; dose: 10 mg; form: take 1 capsule; route: PERSON; frequency: qhs; directions: not available; details: dispense: capsule(s); not taking; status: active; source: tessema,PERSON; date: your orders normal orders this visit humphrey visual field - ou - both eyes oct, optic nerve - ou - both eyes - cirrus; optic disc condition list as of DATE_TIME rosacea sprain of ankle syncope migraine atrial fibrillation hypertrophic cardiomyopathy s/p implantation of automatic cardioverter/defibrillator (aicd) results summary immunizations administered on date of encounter - DATE_TIME none",
"gpt4_summary": "The patient is using latanoprost ophthalmic solution for eyes nightly, suggesting a likely treatment for glaucoma. Other conditions include rosacea, ankle sprain, syncope, migraine, atrial fibrillation, and hypertrophic cardiomyopathy.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09625",
"image_path": "slo_fundus_09625.jpg",
"filename": "data_09625.npz",
"report": "74 y.o. male with suspected glaucoma, showing increased c/d ratio, deep excavated cup, positive family history. OCT tests show superior thinning in right eye, normal left eye. He has vitreomacular traction and is recommended to return for a check. Additionally, patient has a history of keratitis and stable RPE changes.",
"age": 74.32,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "74 y.o. male here for follow-up as glaucoma suspect: \u00ff\u00ff 1. glaucoma suspect increased c/d ratio with large disc overall but deep excavated cup, positive family history PERSON, pachy average/thin tmax 18/17 cct 539/529 hvf full DATE_TIME hvf DATE_TIME: reliable ou, normal DATE_TIME, normal ou oct DATE_TIME: od: superior thinning, os normal DATE_TIME: od borderline sup thin, os normal oct rnfl DATE_TIME: borderline sup thinning od, normal os oct rnfl DATE_TIME: borderline sup thinning od, normal os, stable DATE_TIME: normal ou oct rfnl DATE_TIME: normal ou hvf DATE_TIME: ou full, reliable hvf DATE_TIME: full, reliable ou hvf DATE_TIME: full, reliable ou hvf DATE_TIME: normal ou, reliable hvf DATE_TIME: normal ou, reliable hvf DATE_TIME: borderline reliable od, otherwise full ou \u00ff\u00ff referred to glaucoma, dr. PERSON. physiologic cupping. spectralis oct normal ou. gonio in glaucoma: 'ss 360 with pigment inferiorly at schwalbe's; 3+ pigment to tm' \u00ff\u00ff rec: fu in DATE_TIME for iop check \u00ff\u00ff 2. cataract ou not visually signficant, good acuity, continue observation \u00ff\u00ff 3. rpe changes periphery ou observe, no change \u00ff\u00ff 4. refractive error rx provided\u00ffpreviously, sees well with current glasses does not want new rx \u00ff\u00ff 5. dry eyes uses at as needed rec: - try liquigel (sample given) - gel at DATE_TIME \u00ff\u00ff 6. episode of PERSON keratitis os in DATE_TIME resolved no recurrence \u00ff\u00ff 7. vitreomacular traction ou oct macula DATE_TIME: vmt ou oct macula DATE_TIME: same as previous oct macula DATE_TIME: vmt ou, stable DATE_TIME: vmt ou, stable DATE_TIME: vmt os only (od has resolved) DATE_TIME: vmt os, od normal foveal contour",
"gpt4_summary": "74 y.o. male with suspected glaucoma, showing increased c/d ratio, deep excavated cup, positive family history. OCT tests show superior thinning in right eye, normal left eye. He has vitreomacular traction and is recommended to return for a check. Additionally, patient has a history of keratitis and stable RPE changes.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09626",
"image_path": "slo_fundus_09626.jpg",
"filename": "data_09626.npz",
"report": "57-year-old patient, high myopia, had cataract surgery. IOP elevated initially but is now normal. Borderline IOP prior to surgery, no family history of glaucoma. The C/D ratio a bit high. No diagnosed glaucoma.",
"age": 58.22,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "57 PERSON, here for follow-up after ce/iol od DATE_TIME \u00ff\u00ff 1. high myopia prior to cataract surgery \u00ff\u00ff 2. s/p\u00ffphaco/ pciol on left DATE_TIME doing well, iop elevated on day #1, now good off meds ? 3. borderline iop pre-op no family hx of glaucoma c/d ratio a little high\u00ff\u00ff \u00ff\u00ff pachy 563/552, true iop same as measured baseline oct poor images, will repeat DATE_TIME oct rnfl DATE_TIME: normal ou, ?sup temporal thinning os DATE_TIME: borderline thinning ou hvf DATE_TIME: not very reliable, od full, os with ? inf nasal defects hvf DATE_TIME: full ou \u00ff rec: - cont off drops - return in DATE_TIME, for repeat oct rnfl, dilation \u00ff 4. PERSON happy with vision ok to use otc readers",
"gpt4_summary": "57-year-old patient, high myopia, had cataract surgery. IOP elevated initially but is now normal. Borderline IOP prior to surgery, no family history of glaucoma. The C/D ratio a bit high. No diagnosed glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09631",
"image_path": "slo_fundus_09631.jpg",
"filename": "data_09631.npz",
"report": "The patient suffers from increased intraocular pressure (IOP) in the right eye. They have symptoms in both eyes related to medication side effects. Narrow eye angles persist in the left eye but the right eye is post cataract surgery with a more open eye. There are non-specific defects in the visual field of the right eye.",
"age": 38.7,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "s/PERSON and with iop od up again on just pilo ou (patient also symptomatic to pilo side effects) - better on LOCATION but now with symptoms os and angle still narrow os ? - s/p ce/iol od + ecp on DATE_TIME with deeper chamber and gonio more open goal iop teens for now ? ?? current assessment & plan iop good ou off cosopt for DATE_TIME) hvf with non-specific rim-type defects od worse than os, though nerves have minimal cupping plan: monitor off cosopt follow-up in DATE_TIME iop check, dfe with LOCATION, rnfl oct lens replaced overview s/p LOCATION ecp DATE_TIME s/p phaco/iol os DATE_TIME current assessment & plan the patient is status-post cataract surgery left eye performed on DATE_TIME without complication. mac oct showed no cme to account for vision od. plan: to see optom for refraction PERSON, PERSON",
"gpt4_summary": "The patient suffers from increased intraocular pressure (IOP) in the right eye. They have symptoms in both eyes related to medication side effects. Narrow eye angles persist in the left eye but the right eye is post cataract surgery with a more open eye. There are non-specific defects in the visual field of the right eye.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09633",
"image_path": "slo_fundus_09633.jpg",
"filename": "data_09633.npz",
"report": "The clinical note discusses the use of punctal plugs in case of problems with preservative-free artificial tears. No mention of glaucoma.",
"age": 66.25,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "punctal plugs if difficulty with preservative-free artificial tears. the information above was documented by PERSON as a scribe for PERSON on DATE_TIME.",
"gpt4_summary": "The clinical note discusses the use of punctal plugs in case of problems with preservative-free artificial tears. No mention of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09635",
"image_path": "slo_fundus_09635.jpg",
"filename": "data_09635.npz",
"report": "85 y.o. patient has moderate stage glaucoma & pseudophakia in both eyes. IOP 17/17, CCT 573/571. Macular hole in right eye is stable. Continues with latanoprost treatment.",
"age": 85.87,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "85 y.o. transferring care here. was being followed by dr. PERSON and dr. PERSON in ct poag - moderate stag ou - iop 17/17 - tmax ? - cct 573/571 - oct DATE_TIME od wnl os focal thinning inferiorly but PERSON DATE_TIME od nonspecific defects os borderline unreliable, paracentral defects > continue latanoprost qhs ou pseudophakia ou - looks fine macular hole od stable pdr ou s/p prp ou fu DATE_TIME iop check",
"gpt4_summary": "85 y.o. patient has moderate stage glaucoma & pseudophakia in both eyes. IOP 17/17, CCT 573/571. Macular hole in right eye is stable. Continues with latanoprost treatment.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09639",
"image_path": "slo_fundus_09639.jpg",
"filename": "data_09639.npz",
"report": "The 75-year-old male patient likely has mild primary open angle glaucoma, which was discovered during use of topical steroid. The glaucoma is more prominent in the left eye (os). He has stable arcuate defects and fluctuating visual field changes in the superior part of his eye. He responds well to latanoprost and also has dry age-related macular degeneration (os>od). His vision is 20/25 and also suffers from pterygium.",
"age": 75.13,
"gender": "male",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "75 y.o. male mandarin-speaking (but speaks decent english) healthy - likely mild primary open angle glaucoma os>od fam hx: tmax: 24 os when using topical steroid (used for DATE_TIME); otherwise around 17-20; old notes showed 18/21 prior reports from LOCATION showed cup:disc 0.4/0.6 cct: 561/563 gonio DATE_TIME: ou open to ss with darkly pigmented tm hvf DATE_TIME: od full, os possible early superior arcuate DATE_TIME: od inferior and nasal rim defect, os superior arcuate appeared worse than 7/PHONE_NUMBER: od few scattered defects, os superior arcuate stable from 7/PHONE_NUMBER: od nonspecific defects, os superior arcuate defect, persistent but fluctuates since DATE_TIME ?related to dermatochalasis rnfl DATE_TIME: ou PERSON: ou wnl and stable disc photos: DATE_TIME, DATE_TIME, DATE_TIME last dilated: DATE_TIME given persistent hvf changes os and slightly asymmetric iop, was started on latanoprost with good response >> continue latanoprost ou qhs >> consider taper upper lids with future hvf - dry age related macular degeneration os>od vision stable at 20/25 >> amsler grid monitoring, healthy lifestyle, areds, sunglasses outdoors - pterygium ou stable, not bothersome to patient defers routine refraction at each visit (doesn't want new glasses and doesn't want to pay for refraction) f/up DATE_TIME with macular oct, no dilation, sooner prn mrx only if patient wishes to obtain new glasses",
"gpt4_summary": "The 75-year-old male patient likely has mild primary open angle glaucoma, which was discovered during use of topical steroid. The glaucoma is more prominent in the left eye (os). He has stable arcuate defects and fluctuating visual field changes in the superior part of his eye. He responds well to latanoprost and also has dry age-related macular degeneration (os>od). His vision is 20/25 and also suffers from pterygium.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09641",
"image_path": "slo_fundus_09641.jpg",
"filename": "data_09641.npz",
"report": "The note mentions a female patient with no indication of glaucoma. Conditions include asthma, vitamin D deficiency, iron deficiency anemia, cervical disc disease, abnormal mammogram, and sprained right ankle. Current medication includes beclomethasone and omega 3-DHA-EPA-fish oil. She's allergic to dog dander.",
"age": 60.24,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "PERSON date of birth: DATE_TIME patient PERSON: NUMBER Institution LOCATION phone #: PHONE_NUMBER dept fax #: PHONE_NUMBER susan n morrison DATE_TIME appointment PERSON: NUMBER provider: PERSON mc tech department: Institution comprehensive oph main campus patient demographics address phone e-mail address 260 puritan road swampscott ma 01907 PHONE_NUMBER (home) PHONE_NUMBER (work) *preferred* URLrrison@URL basic information date of birth sex race ethnicity preferred language preferred written language DATE_TIME female white or NRP no NRP NRP future appointments provider department center DATE_TIME DATE_TIME PERSON, LOCATION shore physicians group PERSON DATE_TIME PERSON, LOCATION shore physicians group nsp marblehe reason for visit none vital signs/measurements smoking status never smoker most recent eyeglasses prescription (DATE_TIME) sphere cylinder axis add right -1.75 -1.00 155 +2.00 left plano -0.50 030 +2.00 allergies as of DATE_TIME dog dander medications and orders your current medications beclomethasone (qvar) 80 mcg/actuation inhaler inhale 2 puffs into the lungs 2 (two) times a day. omega 3-dha-epa-fish oil 1,000 mg (120 PERSON) cap take 1 capsule by mouth DATE_TIME. condition list as of DATE_TIME asthma vitamin d deficiency iron deficiency anemia cervical disc disease abnormal mammogram sprain of right ankle results summary immunizations administered on date of encounter - DATE_TIME none",
"gpt4_summary": "The note mentions a female patient with no indication of glaucoma. Conditions include asthma, vitamin D deficiency, iron deficiency anemia, cervical disc disease, abnormal mammogram, and sprained right ankle. Current medication includes beclomethasone and omega 3-DHA-EPA-fish oil. She's allergic to dog dander.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09642",
"image_path": "slo_fundus_09642.jpg",
"filename": "data_09642.npz",
"report": "68 y.o. patient with primary open-angle glaucoma (poag) in the left eye (os). Undergoing treatment with latanoprost with plans to add cosopt. Non-specific defects in visual field, thin area in os.",
"age": 68.51,
"gender": "male",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "married or partnered",
"note": "68 y.o. new patient to me referred by Institution ew poor historian. poag os, suspect PERSON DATE_TIME - hvf DATE_TIME od nonspecific defects os sup and PERSON - oct DATE_TIME od wnl os thin sup/PERSON suboptimal on latanoprost 13/20 > add cosopt to os > fu DATE_TIME for iop check eye irritation - warm compresses - artificial tears",
"gpt4_summary": "68 y.o. patient with primary open-angle glaucoma (poag) in the left eye (os). Undergoing treatment with latanoprost with plans to add cosopt. Non-specific defects in visual field, thin area in os.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09643",
"image_path": "slo_fundus_09643.jpg",
"filename": "data_09643.npz",
"report": "Patient scheduled for complex cataract and g-probe cyclophotocoagulation surgery in left eye due to secondary glaucoma and age-related cataract. Not on blood thinners.",
"age": 68.63,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "please schedule this patient (PERSON) for surgery: complex cataract and g-probe cyclophotocoagulation laterality: left eye surgeon: PERSON, LOCATION level: 3 diagnoses associated with this procedure for booking: indeterminate stage secondary glaucoma of left eye due to combination mechanisms; combined forms of age-related cataract of left eye anesthesia: mac plus block by anesthesia team case duration: 45 minutes operating time blood thinners: this patient is not on blood thinners please send me confirmation message with the date when scheduled. thank you!",
"gpt4_summary": "Patient scheduled for complex cataract and g-probe cyclophotocoagulation surgery in left eye due to secondary glaucoma and age-related cataract. Not on blood thinners.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09646",
"image_path": "slo_fundus_09646.jpg",
"filename": "data_09646.npz",
"report": "The patient has stable chronic illnesses with good intraocular pressure (IOP) control. The patient has a moderate risk of glaucoma progression without care, continuing on a prescription drug regimen.",
"age": 89.75,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "DATE_TIME, DATE_TIME, and DATE_TIME. -long discussion with patient on DATE_TIME: given stable chronic illnesses with good iop control, we will continue monitoring the patient on the prescription drug regimen described above. importance of follow-up explained to patient given moderate risk of progression without care. -rtc in DATE_TIME with iop check ou, hvf 24-2 size v ou (with experienced technician), PERSON, and oct rnfl/gcc od (with experienced technician), sooner prn. the information above was documented by Person as a scribe for PERSON on DATE_TIME. i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "The patient has stable chronic illnesses with good intraocular pressure (IOP) control. The patient has a moderate risk of glaucoma progression without care, continuing on a prescription drug regimen.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09648",
"image_path": "slo_fundus_09648.jpg",
"filename": "data_09648.npz",
"report": "Patient complains of earache, headache, and weight loss due to jaw pain. Risk of cardiac impacts and blindness in left eye if current condition worsens. Has kidney dysfunction, history of lamellar hole, iritis, scleritis, uveitis- potentially autoimmune. No mention of glaucoma.",
"age": 74.01,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "ear ache after on DATE_TIME, then headache all over head, couldn't even touch his scalp - has lost weight, but thinks this is due to not eating much from jaw pain - denies fevers - discussion had with dean and his wife PERSON about the gravity of this condition and potential cardiac impacts as well as risk of blindness in the left eye if untreated, they were concerned about his chf and i recommended they discuss that with the providers in the ed # posterior vitreous detachment os - extended ophthalmoscopy shows no retinal tears/detachment. - rd precautions # iritis od/scleritis od - quiet DATE_TIME observe - non granulomatous acute anterior uveitis od - onset DATE_TIME after bronchitis, could be auto-immune - has kidney dysfunction, will be careful with valtrex if needed will check with pcp - resolved, observe # s/p ce/iol os DATE_TIME # s/p ce/iol od (dr. DATE_TIME) - good post-op result - open pc s/p yag os - observe # mild erm os - not visually significant, erm obtained in past - observe # history of lamellar hole od s/p ppv by PERSON DATE_TIME - stable, observe patient sent to ed DATE_TIME emergently rtc to me in DATE_TIME, oct macula for epiretinal membrane os PERSON, PERSON personally spent a total of DATE_TIME on care for this patient on the date of the encounter. this includes face-to-face time during the visit as well as non face-to-face time spent on chart review, documentation, and care coordination.",
"gpt4_summary": "Patient complains of earache, headache, and weight loss due to jaw pain. Risk of cardiac impacts and blindness in left eye if current condition worsens. Has kidney dysfunction, history of lamellar hole, iritis, scleritis, uveitis- potentially autoimmune. No mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09650",
"image_path": "slo_fundus_09650.jpg",
"filename": "data_09650.npz",
"report": "The patient is a glaucoma suspect with large c/d, possibly due to physiological cupping from large nerves. He has a family history of glaucoma, increasing eye pressure, and borderline temporal thinning. He's starting treatment for eye pressure, followed by an IOP check.",
"age": 56.72,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "DATE_TIME man with htn: last saw me DATE_TIME \u00ff 1. refractive error: mild myopic astigmatism \u00ff 2. glaucoma suspect based on large c/d: probably physiologic cupping from large nerves; --+fam hx (mother and father) --tc 21, 21 last 18,18 by applanation by md --hvf DATE_TIME: os unreliable with 9/10 fl but full; od reliable and full DATE_TIME: reliable and full; DATE_TIME: reliable and full ou, DATE_TIME: reliable, normal ou --nfl DATE_TIME: normal od, tr temp thinning PERSON oct DATE_TIME: normal od, borderline temporal thinning PERSON DATE_TIME: normal od; borderline temporal thinning os \u00ff --disc photos DATE_TIME: od: c/d 0.5, healthy rims; os: c/d 0.5, healthy rims-- looks same compared to DATE_TIME --cct 557/560 * given increasing eye pressure with significant family history, will start on PERSON covered by insurance * return in DATE_TIME for iop check only \u00ff 3.dysfunctional tear syndrome: PERSON with warm compresses, lid hygiene, and artificial tears was discussed with the patient. \u00ff 4. scleral show ou: symmetric proptosis on hertel's, no other evidence of thyroid PERSON --per patient, thyroid testing normal, no diplopia \u00ff follow up 2-3 m for iop check only after DATE_TIME for dilated comprehensive exam with glaucoma testing",
"gpt4_summary": "The patient is a glaucoma suspect with large c/d, possibly due to physiological cupping from large nerves. He has a family history of glaucoma, increasing eye pressure, and borderline temporal thinning. He's starting treatment for eye pressure, followed by an IOP check.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09651",
"image_path": "slo_fundus_09651.jpg",
"filename": "data_09651.npz",
"report": "The patient is a 60-year-old ophthalmology chair and retina surgeon with hypertension and history of thyroid cancer. There is an indication of c/d asymmetry os>od with a family history of glaucoma. Noted superior thinning in both eyes, possibly due to pvd. Also, a new pvd was observed in the left eye. Overminused vision corrected with lens prescription updates.",
"age": 60.66,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "60 yo ophthalmology chair and retina surgeon with history of htn, s/p total thyroidectomy for papillary thyroid ca DATE_TIME, s/p rai for 3 positive nodes, osteopenia lee DATE_TIME 1. c/d asymmetry os>od with fhx glaucoma tmax DATE_TIME. cct PERSON (thick). PERSON (maternal grandmother went blind from glaucoma) hvf DATE_TIME: full ou hvf DATE_TIME: full ou oct DATE_TIME: od borderline superior thinning. similar to prior, may be temporalization of curve. os borderline superior and nasal thinning. similar to prior DATE_TIME: od superior thinning (but missing data, likely due to pvd). PERSON: wnl ou (borderline PERSON) -follown thinning. DATE_TIME. guttae ou cct DATE_TIME: PERSON cct DATE_TIME: DATE_TIME 571/581 > more prominent DATE_TIME and perhaps contributing to some visual sx along with sl incr in cataract od>os. no edema, cct stable. will follow 3. lattice os and cr scars os>od -stable 4. pvd od, very dense, old. new pvd os noted DATE_TIME. des: taking fish oil supplements and using systane prn **overminused od>os, symptomatic >> given updated mrx DATE_TIME >> slightly overminused again DATE_TIME >> updated mrx DATE_TIME. will not change cyl axis os given no complains os",
"gpt4_summary": "The patient is a 60-year-old ophthalmology chair and retina surgeon with hypertension and history of thyroid cancer. There is an indication of c/d asymmetry os>od with a family history of glaucoma. Noted superior thinning in both eyes, possibly due to pvd. Also, a new pvd was observed in the left eye. Overminused vision corrected with lens prescription updates.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09655",
"image_path": "slo_fundus_09655.jpg",
"filename": "data_09655.npz",
"report": "Patient, a retired bartender, suspected of glaucoma due to increased cup to disc ratios. IOP normal, no family history. Also has hyperopia, astigmatism, presbyopia and dry eye syndrome.",
"age": 74.25,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "impression and plan: DATE_TIME who is retired from being a bartender at the boston convention center 1. glaucoma suspect -based on increased cup to disc ratios ou -pachy DATE_TIME on within normal limits ou -iop remain normal -no family history 2. hyperopia, astigmatism and presbyopia ou -rx for glasses provided 3. mgd and evaporative dry eye syndrome -warm compresses and eyelid hygiene PERSON with oct on, gc segmentation and vf 24-2 PERSON, md",
"gpt4_summary": "Patient, a retired bartender, suspected of glaucoma due to increased cup to disc ratios. IOP normal, no family history. Also has hyperopia, astigmatism, presbyopia and dry eye syndrome.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09661",
"image_path": "slo_fundus_09661.jpg",
"filename": "data_09661.npz",
"report": "The patient has trauma or kidney disease. The maximum intraocular pressure and central corneal thickness aren't stated. The gonioscopy, HVF, and RNFL results are unclear. The patient has allergies to glaucoma medications and previous intraocular surgeries. The OCT-GCC findings, IOP goals and underlying social/systemic issues are undefined. The presence of glaucoma isn't confirmed.",
"age": 69.8,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "trauma or kidney disease central corneal thickness (cct - ***): *** tmax (maximum intraocular pressure recorded - ***): *** iop (***): mmhg not recorded gonioscopy (***): od: {gonio findings:19197::'open','narrow','closed','unable','pending'} os: {gonio findings:19197::'open','narrow','closed','unable','pending'} allergies to glaucoma medications: *** prior intraocular surgeries: *** prior history of lasers: *** last hvf (***): od: {hvf findings:19197::'baseline','stable','stable and full','worsened','improved from prior','unable','pending'} os: {hvf findings:19197::'baseline','stable','stable and full','worsened','improved from prior','unable','pending'} DATE_TIME rnfl (***): od: average thickness *** microns, {oct rnfl findings:19197::'baseline','stable','stable and full','worsened','improved from prior','unable','pending'} os: average thickness *** microns, {oct rnfl findings:19197::'baseline','stable','stable and full','worsened','improved from prior','unable','pending'} last oct gcc (***): od: {oct gcc findings:19197::'baseline','stable','worsened','improved from prior','unable','pending'} os: {oct gcc findings:19197::'baseline','stable','worsened','improved from prior','unable','pending'} baseline optic disc photos: {baseline photoes:19197::'unable','pending'} 2. 3. social/systemic issues: *** attending's plan: -goal intraocular pressure {goal pressure:19197::'~','less than or equal to','=','greater than or equal to'} *** mmhg, right eye -goal intraocular pressure {goal pressure:19197::'~','less than or equal to','=','greater than or equal to'} *** mmhg, left eye",
"gpt4_summary": "The patient has trauma or kidney disease. The maximum intraocular pressure and central corneal thickness aren't stated. The gonioscopy, HVF, and RNFL results are unclear. The patient has allergies to glaucoma medications and previous intraocular surgeries. The OCT-GCC findings, IOP goals and underlying social/systemic issues are undefined. The presence of glaucoma isn't confirmed.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09666",
"image_path": "slo_fundus_09666.jpg",
"filename": "data_09666.npz",
"report": "Patient takes depakote, nadolol, tiotropium, and latanoprost (for eyes). Orders for visual field and optic nerve tests. Conditions include headache, seizure disorder, sensorineural hearing loss.",
"age": 64.86,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "route every 4 (DATE_TIME as needed for pain (specific location in comments). PERSON (depakote oral) (taking) take by mouth. nadolol oral (taking) take by mouth. tiotropium (PERSON) 18 mcg inhalation capsule (taking) inhale 18 mcg into the lungs DATE_TIME. latanoprost (xalatan) 0.005 % ophthalmic solution place 1 drop into each eye nightly. your orders normal orders this visit humphrey visual field - ou - both eyes oct, optic nerve - ou - both eyes - cirrus condition list as of DATE_TIME headache seizure disorder sensorineural hearing loss resultsATE_TIME.",
"gpt4_summary": "Patient takes depakote, nadolol, tiotropium, and latanoprost (for eyes). Orders for visual field and optic nerve tests. Conditions include headache, seizure disorder, sensorineural hearing loss.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09670",
"image_path": "slo_fundus_09670.jpg",
"filename": "data_09670.npz",
"report": "The patient has primary open angle glaucoma in both eyes, with the condition worsening in the left eye. They have a history of disc heme in the right eye, possible changes in the left eye, and cataracts starting to develop. Therapy under consideration.",
"age": 76.18,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "other",
"maritalstatus": "married or partnered",
"note": "attending assessment & plan - primary open angle glaucoma ou, os> od. tmax 24.5/25.5. h/o disc heme od. cct 500 ou allergy to ag, sulfa allergy but PERSON. possible on change os in DATE_TIME. dp's stable in 11/15. vf 10/12 fluct os, better in 4/13 os, stable ou in 3/16 angles slightly narrow, no iop elevation after dil in 1/17 goal iop high teens od, mid teens os - at goal od, borderline os plan: - azopt bid od and inc to tid os. monitor os closely, may need additional therapy. - consider slt for os if iop still borderline. - early cataracts os>od - monitor. - dm diagnosed in DATE_TIME, no dr in 1/17 rtc in 2 mo for iop check.",
"gpt4_summary": "The patient has primary open angle glaucoma in both eyes, with the condition worsening in the left eye. They have a history of disc heme in the right eye, possible changes in the left eye, and cataracts starting to develop. Therapy under consideration.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09672",
"image_path": "slo_fundus_09672.jpg",
"filename": "data_09672.npz",
"report": "71-year-old white, non-Hispanic male with no diagnosis of glaucoma.",
"age": 71.22,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "a 71 y.o. white, non-hispanic male with no diagnosis of glaucoma. accurate. PERSON, md",
"gpt4_summary": "71-year-old white, non-Hispanic male with no diagnosis of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09674",
"image_path": "slo_fundus_09674.jpg",
"filename": "data_09674.npz",
"report": "Ms. PERSON has optic neuropathy related to optic disc drusen. She's under Dr. PERSON's care for glaucoma and IOP lowering therapy. MRI showed no optic nerve abnormalities but multiple T2 white matter lesions. Referred to Dr. PERSON for potential neuro-inflammatory disorder. No symptom history apart from vertigo. Will continue latanoprost, goal of low teens IOP. Further consultation scheduled in DATE_TIME.\n",
"age": 41.58,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "ms. PERSON has optic neuropathy which was thought to be related to optic disc drusen. an mri of the orbits (DATE_TIME) with contrast did not show any abnormalities of the optic nerve. she is being followed by glaucoma (dr. PERSON) to assist with iop lowering therapy which may be helpful to slow progression of visual field loss related to optic disc drusen. there was concern in DATE_TIME of her iops measuring 20 mm hg in both eyes with a mild worsening in the nfl thinning os and mild worsening of her nasal visual field defect os. in follow up DATE_TIME she had an mri of the brain as part of a workup of vertigo, which shows numerous t2 white matter lesions which are periventricular, subcortical, and a few that are juxtacortical. i am concerned these are clinically silent ms lesions given the lesion distribution. she has no history of symptoms referable to them other than possibly the vertigo/imbalance, though by history that sounded like bppv. i discussed the concerns at length with her and her husband PERSON (by phone). i have recommended that she see dr. PERSON at Institution for further evaluation as to whether she has a demyelinating or other neuro-inflammatory disorder. PERSON DATE_TIME were acceptable and the visual fields are stable, but she should still re-establish care with dr. PERSON. i will plan to see her back in DATE_TIME. recommendations: 1. referral to dr. PERSON at Institution 2. continue latanoprost, follow up with dr. PERSON regarding iop lowering. goal of low teens. 3. scheduled follow up with me in DATE_TIME. i personally spent a total of DATE_TIME on care for this patient on the date of the encounter. this includes face-to-face time during the visit as well as non face-to-face time spent on chart documentation, and care coordination. PERSON, LOCATION.",
"gpt4_summary": "Ms. PERSON has optic neuropathy related to optic disc drusen. She's under Dr. PERSON's care for glaucoma and IOP lowering therapy. MRI showed no optic nerve abnormalities but multiple T2 white matter lesions. Referred to Dr. PERSON for potential neuro-inflammatory disorder. No symptom history apart from vertigo. Will continue latanoprost, goal of low teens IOP. Further consultation scheduled in DATE_TIME.\n",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09678",
"image_path": "slo_fundus_09678.jpg",
"filename": "data_09678.npz",
"report": "The patient, a female, is a suspect for glaucoma, largely based on the appearance of her optic cup-to-disc ratio. Medical history shows a blunt trauma to the left eye in the past. No family history of glaucoma. IOP (15/16) and CCT (565/548) are also noted. Macular scar detected in left eye due to previous blunt trauma. Patient has senile cataract in her right eye which is not significantly impacting her daily activities. A new prescription for eyeglasses was issued.",
"age": 64.4,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "PERSON is a DATE_TIME. female glaucoma suspect based on cup:disc appearance ou +h/o blunt trauma os (DATE_TIME from punch to eye) prior notes from dimock from DATE_TIME: iop 15/16 fam hx: none tmax: 15/16 cct: 565/548 gonio DATE_TIME: ou open to ptm/ss (faintly pigmented tm) hvf DATE_TIME: od dense superior defect (?lid), os possible inferior arcuate DATE_TIME: od resolved superior arcuate, os dense inferior>superior arcuate (unreliable) DATE_TIME: ou unreliable with fluctuating defects each visit DATE_TIME: PERSON. rnfl DATE_TIME: ou wnl macular scar os history of blunt trauma DATE_TIME. pupil slightly decentered retinal detachment precautions discussed combined senile cataract od>os not visually significant and not affecting activities of DATE_TIME living observe refractive error a prescription for new glasses was given to the patient. f/u in DATE_TIME for LOCATION, oct, hvf 24-2.",
"gpt4_summary": "The patient, a female, is a suspect for glaucoma, largely based on the appearance of her optic cup-to-disc ratio. Medical history shows a blunt trauma to the left eye in the past. No family history of glaucoma. IOP (15/16) and CCT (565/548) are also noted. Macular scar detected in left eye due to previous blunt trauma. Patient has senile cataract in her right eye which is not significantly impacting her daily activities. A new prescription for eyeglasses was issued.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09681",
"image_path": "slo_fundus_09681.jpg",
"filename": "data_09681.npz",
"report": "Stable optical coherence tomography; fluctuating but normal Humphrey visual field; intraocular pressure managed with medication in left eye; post-surgery right eye is good; glaucoma not mentioned.",
"age": 74.87,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "ora optical coherence tomography is stable, humphrey visual field fluctuates (but is within the realm of older tests) intraocular pressure ok on dorzolamide/timolol and brimonidine left eye right eye looks great after surgery return to clinic DATE_TIME with intraocular pressure check, humphrey visual field and dilation",
"gpt4_summary": "Stable optical coherence tomography; fluctuating but normal Humphrey visual field; intraocular pressure managed with medication in left eye; post-surgery right eye is good; glaucoma not mentioned.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09683",
"image_path": "slo_fundus_09683.jpg",
"filename": "data_09683.npz",
"report": "48-year-old female with signs of primary open-angle glaucoma (POAG) based on c:d asymmetry and history of advanced glaucoma in mother. Current IOP controlled. Has posterior vitreous detachment, no retinal issues were found.",
"age": 48.83,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "48 y.o. female 1. poag(s) based on c:d asymmetry od> started on wc, also noted to have c/d asymmetry od>os \u00ff 1. hx rll pyogenic granuloma -asx, resolved over DATE_TIME \u00ff 2. c/d asymmetry od>os -noted since DATE_TIME, followed by dr. PERSON records show tmax 22. cct DATE_TIME: 581 ou (thick). +mother (PERSON, has mmg, s/p lpi ou, on xalatan ) \u00ff hvf DATE_TIME DATE_TIME: full ou hvf DATE_TIME: full ou oct today DATE_TIME: PERSON. os borderline temporal thinning oct DATE_TIME: wnl ou oct DATE_TIME: wnl ou oct DATE_TIME: PERSON. PERSON st thinning disc photos DATE_TIME: 0.65 ou >> will follow \u00ff 3. cr scar od \u00ff 4. refractive error >> updated mrx DATE_TIME (using glasses for driving, but uncomfortable walking with them unless +1.50 otc readers. would like to obtain rx sunglasses) \u00ff 5. cataracts ou - not visually significant \u00ff 6. isolated ma os DATE_TIME -hba1c 6.0% DATE_TIME >> encouraged efforts with diet and healthy lifestyle, to f/u with pcp",
"gpt4_summary": "The 64-year-old patient, a copier technician/mechanic with a history of hypercholesterolemia, is observed to have an asymmetric optic disc which might indicate potential glaucoma, but requires further monitoring. Patient also has cataracts.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09703",
"image_path": "slo_fundus_09703.jpg",
"filename": "data_09703.npz",
"report": "The patient has enlarged optic nerve cups but shows normal neuro-ophthalmic function. Likely has physiologic cupping, with mild sloping of superior disc, which requires monitoring. No glaucoma detected.",
"age": 29.74,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "may DATE_TIME, 2020 PERSON, LOCATION NUMBER date of birth: PERSON date of visit: DATE_TIME dear dr. PERSON: thank you for referring PERSON to me for evaluation. below are the relevant portions of my note. if you have questions, please do not hesitate to call me. i look forward to following PERSON along with you. sincerely, PERSON, PERSON PERSON, LOCATION LOCATION street LOCATION DATE_TIME via facsimile: PHONE_NUMBER adam g. this patient is referred by his optometrist for concern over enlarged optic nerve cups. the neuro-ophthalmic exam shows normal afferent and efferent function. dilated fundus exam were shows mild sloping of the right optic nerve superiorly with c/d of 0.55 and 0.5 os. oct of the retinal gcc was normal ou. i suspect that this patient most likely has physiologic cupping given his age and excellent visual function. there is mild sloping of the superior disc PERSON which should be monitored with DATE_TIME eye exams and periodic visual field testing. it is reassuring that the retinal gcc analysis (a sensitive marker for optic nerve health) is normal ou. there is no clear explanation for his perception of decreased vision od when the lights are out in his bedroom but i reassured him that this symptom is almost surely benign. impression: 1. physiologic optic disc cupping, though with slight asymmetry recommendations: 1. follow-up neuro-ophthalmic examination prn 2. at least yearly general eye exams note prepared with the assistance of PERSON DATE_TIME, md, fellow.",
"gpt4_summary": "The patient has enlarged optic nerve cups but shows normal neuro-ophthalmic function. Likely has physiologic cupping, with mild sloping of superior disc, which requires monitoring. No glaucoma detected.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09708",
"image_path": "slo_fundus_09708.jpg",
"filename": "data_09708.npz",
"report": "Patient with borderline glaucoma in both eyes and a family history of glaucoma. Intraocular pressure of 21 in right eye. Observed thinning of ganglion cell layer in both eyes, but more pronounced in right. Patient's glaucoma may be associated with steroid use.",
"age": 62.64,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "steroid responders borderline glaucoma ou hx of family glaucoma, dad. t corr +1 od 0 os iop DATE_TIME od 21 os. ?lens rim artifact od, blind spot shift. thin gcl od>os, thin onh nfl od>os pvd os no holes or tears. dad had PERSON and buckle--blind from this in one eye per pt. PERSON had rd and was blind in one eye as well. nuclear sclerosis ou seems mild. pt has glare. observe hold on latanoprost for now--could consider if the steroid dose or iop goes up cpm with betoptic and alphagan. pt knows to come in for iop check if steroids have to be increased. on celcept and actemra as well as 5 mg of prednisone. taking salsalate PERSON as she cannot take naproxen. myopia dad with LOCATION. vision change od has now resolved noticed gray spot on right paracentral/inferior field of view. this was unilateral change od. followed by her typical vision migraine aura that was bilateral. migraine went away, gray spot was gone within DATE_TIME. there is an area on hvf that could correspond with gray spot seen by patient. no hollenhorst plaques, clots, bleeding or ischemic areas. she will call for any changes. DATE_TIME f/PERSON, LOCATION, oct.",
"gpt4_summary": "Patient with borderline glaucoma in both eyes and a family history of glaucoma. Intraocular pressure of 21 in right eye. Observed thinning of ganglion cell layer in both eyes, but more pronounced in right. Patient's glaucoma may be associated with steroid use.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09709",
"image_path": "slo_fundus_09709.jpg",
"filename": "data_09709.npz",
"report": "Patient has longstanding, unchanged intermittent floaters but denies flashes and ocular pain. Reports irritation and fbs presence in right eye. No glaucoma mentioned.",
"age": 73.96,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "only. pt denies flashes but notes longstanding intermittent floaters ou,unchanged. (-) ocular pain, double vision, itchy but c/o fbs and irritation od x DATE_TIME. hemoglobin a1c - external date value ref range status DATE_TIME 6.4 % final ---------- fasting blood sugar 130 DATE_TIME before lunch per pt ocular meds: none DATE_TIME: hvf ful ou rtc1 year with oct rnfl only 1-2 years round plastic tiny fb removed from inside of upper lid at slit lamp, recommend .ats ou prn",
"gpt4_summary": "Patient has longstanding, unchanged intermittent floaters but denies flashes and ocular pain. Reports irritation and fbs presence in right eye. No glaucoma mentioned.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09710",
"image_path": "slo_fundus_09710.jpg",
"filename": "data_09710.npz",
"report": "The patient has stable primary open angle glaucoma in both eyes, with consistent visual field and reduced intraocular pressure. Treatments include latanoprost, dorzolamide/timolol, and brimonidine. Mild cataracts present.",
"age": 65.82,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "# primary open angle glaucoma, both eyes - stable DATE_TIME, visual field same as in DATE_TIME and intraocular pressure lower (max around DATE_TIME) - continue latanoprost once nightly both eyes, dorzolamide/timolol 2 times per day both eyes, brimonidine 2 times per day right eye, daily both eyes and mzm - he is following with fechner in LOCATION and here DATE_TIME - return to clinic DATE_TIME for intraocular pressure check, humphrey visual field both eyes, dilate, optical coherence tomography both eyes \u00ff # cataract, both eyes - mild, not visually significant, monitor",
"gpt4_summary": "The patient has stable primary open angle glaucoma in both eyes, with consistent visual field and reduced intraocular pressure. Treatments include latanoprost, dorzolamide/timolol, and brimonidine. Mild cataracts present.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09718",
"image_path": "slo_fundus_09718.jpg",
"filename": "data_09718.npz",
"report": "Patient has uveitis causing head swelling, visual field defects suggesting optic nerve involvement, vitreous hemorrhage, and retinal hemorrhages. Cause of uveitis is unknown. Glaucoma isn't mentioned.",
"age": 55.56,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "head swelling is epiphenomenal to the uveitis. the finding of regional deficits in the visual field strongly suggests direct involvement of the right optic nerve, presumably by the same process that has caused the uveitis. as such, the primary goal should be to seek a cause of the uveitis, although i explained to the patient that it is not uncommon for a specific cause of uveitis not to be found, at least in the initial investigation. an unusual feature of his presentation is the vitreous hemorrhage, which was significant enough to prompt surgery to remove the blood. the cause of the hemorrhage is not clear. notably, i found two small retinal hemorrhages and an epiretinal membrane in the inferior macula od. the latter could have resulted from the inflammation. i doubt that the former is related to the vitreous hemorrhage and perhaps they are simply the result of the epiretinal membraine. diagnoses. 1. history of uveitis, each eye sequentially, unknown explanation 2. status post vitreous hemorrhage, od, ? etiology 3. epiretinal membrane, od, presumably secondary to uveitis recommendations. 1. return in DATE_TIME. continue uveitis work-up as had been planned PERSON, PERSON, neuro-ophthalmology service i spent a total of DATE_TIME preparing and caring for this patient (face-to-face and non face-to-face); formulating (including review of the presentation with the resident or fellow or review of medical tests) and finalizing the note.]",
"gpt4_summary": "Patient has uveitis causing head swelling, visual field defects suggesting optic nerve involvement, vitreous hemorrhage, and retinal hemorrhages. Cause of uveitis is unknown. Glaucoma isn't mentioned.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09719",
"image_path": "slo_fundus_09719.jpg",
"filename": "data_09719.npz",
"report": "Male patient is a glaucoma suspect, with age and other risks such as c/d asym and deep cupping. No family history of glaucoma, recent tests normal. Advised warm compresses for styes. Has dry eye, hyperopia, astigmatism, presbyopia, mild cataracts, dermatochalasis, and ptosis.",
"age": 62.21,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "PERSON is a DATE_TIME. male glaucoma suspect ou risks include: age, c/d asym, deep cupping od > os iop wnl ou. Tcorr +1 OD 0 OS will get old notes from INSTITUTION ophthalmologist--(it sounds like they were concerned for glaucoma as well and did an oct) no family hx oct rnfl and gcl normal ou hvf 24-2 normal ou h/o several styes s/p excision of chalazion of right upper eyelid DATE_TIME PERSON advised pt to use warm compresses, just covering the surface off the styes at's prn dry eye ou gave pt dry eye handout recommend at's prn avoid heat/rubbing hyperopia w/ astigmatism and presbyopia ou didn't use reading glasses until DATE_TIME he is doing a bit of monovision mild cataracts ou observe, not visually significant dermatochalasis, bilateral ptosis, bilateral observe f/u in DATE_TIME for oct, NRP, ar/refract",
"gpt4_summary": "Male patient is a glaucoma suspect, with age and other risks such as c/d asym and deep cupping. No family history of glaucoma, recent tests normal. Advised warm compresses for styes. Has dry eye, hyperopia, astigmatism, presbyopia, mild cataracts, dermatochalasis, and ptosis.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09726",
"image_path": "slo_fundus_09726.jpg",
"filename": "data_09726.npz",
"report": "The patient has open-angle glaucoma based on increased cup to disc ratio. Tobradex was used post operation which responded quickly. The patient shows constriction in their visual field but it appears stable and they haven't noticed changes. The intraocular pressure goal is less than 20. They show possible progression in nerve appearance, but their nerve photo is stable. Current plan is to monitor the patient without eye drops and return to the clinic in 9-12 months.",
"age": 77.29,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "prior LOCATION pt. # oag(s) based on increased c:d ratio ou tmax 35 od (postop, in the setting of tobradex use, quickly responeded to LOCATION and PERSON) PERSON negative cct 527 ou hvf os essentially full, gvf od showed generalized constriction that appears stable DATE_TIME oct os wnl DATE_TIME goal iop <20 watching os closely because of nerve appearance \u00ff gvf very constricted od with possible progression vs. variability given low vision od. PERSON has not noted any visual field changes. nerve photo stable to exam from DATE_TIME. \u00ff # h/o rd od s/p sb - stable plan: vf os normal, od improved rnfl oct stable iop acceptable monitor off drops rtc 9-12 LOCATION, hvf os, LOCATION, oct ou seeing dr. PERSON soon as well \u00ff",
"gpt4_summary": "The patient has open-angle glaucoma based on increased cup to disc ratio. Tobradex was used post operation which responded quickly. The patient shows constriction in their visual field but it appears stable and they haven't noticed changes. The intraocular pressure goal is less than 20. They show possible progression in nerve appearance, but their nerve photo is stable. Current plan is to monitor the patient without eye drops and return to the clinic in 9-12 months.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09737",
"image_path": "slo_fundus_09737.jpg",
"filename": "data_09737.npz",
"report": "The clinical note does not provide details on the presence of glaucoma in the patient's condition.",
"age": 28.05,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "options on her arrival, though we discussed local referral if she returns to LOCATION. i will plan to see ms. PERSON in follow-up as needed, although she understood to contact me with any questions or concerns. thank you for the opportunity to participate in ms. PERSON's care. sincerely, PERSON, PERSON than DATE_TIME were spent during this encounter and in reviewing the medical record.",
"gpt4_summary": "The clinical note does not provide details on the presence of glaucoma in the patient's condition.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09739",
"image_path": "slo_fundus_09739.jpg",
"filename": "data_09739.npz",
"report": "Patient has primary angle closure glaucoma. History of glaucoma in family (paternal aunt). Has been experiencing severe headaches. Continuing with prescribed eye medication, but considering lens extraction for long-term IOP control. Consent for LPI OS obtained. Has iris ischemia. No social/systemic issue.",
"age": 39.1,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "? # primary angle closure glaucoma od / primary angle closure os - cct (596/564); tmax DATE_TIME od / 22 os; PERSON of glaucoma (paternal aunt) - h/o r-sided headaches since DATE_TIME escalating in severity; came to ew DATE_TIME with aacg od iop in DATE_TIME when headaches did not resolve - hvf with nonspecific changes ou (1st field) - oct-rnfl (111/101) wnl ou - gonioscopy shows occludable angles ou - s/p lpi od (DATE_TIME) ? - continue LOCATION bid od - continue LOCATION 1% bid od - recommend lpi os (temporal) - ?risks, benefits, alternatives of lpi os explained in detail to patient, including but not limited to bleeding, pain, decreased vision, dysphotopsias, and need for another procedure. informed consent obtained. patient expresses understanding and wishes to proceed. - extensive discussion with patient about continuing medical management od vs lens extraction per eagle trial; explained that lens extraction will not correct pupil function but is likely to be helpful for long-term iop control - patient to consider lens extraction and is agreeable to continuing eye drops as above in the interim # iris ischemia/fixed pupil od - due to aacg as above - does have some mild photophobia od which is likely due to poor pupil function - follow for now ? social/systemic: none plan for lpi os (temporal) as above i have spent greater than half of this DATE_TIME encounter counseling the patient on angle closure glaucoma, treatment options, and risk of vision loss from prolonged elevated intraocular pressure.",
"gpt4_summary": "Patient has primary angle closure glaucoma. History of glaucoma in family (paternal aunt). Has been experiencing severe headaches. Continuing with prescribed eye medication, but considering lens extraction for long-term IOP control. Consent for LPI OS obtained. Has iris ischemia. No social/systemic issue.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09741",
"image_path": "slo_fundus_09741.jpg",
"filename": "data_09741.npz",
"report": "Patient has mild primary open angle glaucoma in the left eye and is a suspect for right eye. They were prescribed Latanoprost. Noted OCT RNFL defect previously. Gonioscopy shows long CBB OU.",
"age": 36.88,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "first seen by Person on DATE_TIME. saw dr. PERSON a few months ago who saw an oct rnfl defect and prescribed latanoprost. diagnosis: mild primary open angle glaucoma, left eye; suspect right eye target iop: / , tmax: ( ) / ( ) central corneal thickness: 553 / 552 gonioscopy: long cbb ou refractive error: od -3.75 . DATE_TIME . 120 / os -4.00 . -1.00 . 050 optic nerve/rnfl findings on baseline visit right eye (DATE_TIME): full optic nerve/rnfl findings on baseline visit left eye (DATE_TIME): green disease with corresponding superotemporal gcipl thinning visual fields on baseline visit right eye (DATE_TIME): grossly full visual fields on baseline visit left eye (DATE_TIME): non-specific superior defects medication history at first visit: latanoprost 1/1 medication intolerances: glaucoma procedures right eye: glaucoma procedures left eye: other eye procedures right eye: other eye procedures left eye: other eye problems right eye: other eye problems left eye: family history: mgm steroids: no trauma: no asthma: no other medical history and problems: assessment: 1. primary open angle glaucoma, mild left eye; suspect right eye -pre-treatment iop 18 -target iop 16 plan: -continue lat 1/1 rtc in 3 months for dfe and disc photos",
"gpt4_summary": "Patient has mild primary open angle glaucoma in the left eye and is a suspect for right eye. They were prescribed Latanoprost. Noted OCT RNFL defect previously. Gonioscopy shows long CBB OU.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09748",
"image_path": "slo_fundus_09748.jpg",
"filename": "data_09748.npz",
"report": "The clinical note does not provide any information regarding the presence of glaucoma. Other mentioned details include nystagmus and patient gateway activation.",
"age": 31.7,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "DATE_TIME condition list as of DATE_TIME nystagmus results summary immunizations administered on date of encounter - DATE_TIME none patient gateway activation information your account is ready to use. LOCATION.",
"gpt4_summary": "The clinical note does not provide any information regarding the presence of glaucoma. Other mentioned details include nystagmus and patient gateway activation.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09750",
"image_path": "slo_fundus_09750.jpg",
"filename": "data_09750.npz",
"report": "58yo with hyperlipidemia, injured by squash racket causing corneal abrasion. Notes occasional floaters. Suspected glaucoma due to c/d asymmetry; low suspicion, borderline IOP. Mild cataracts present.",
"age": 58.5,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "58 yo banker with history of hyperlipidemia his mother was raised in LOCATION (NRP) was struck by partner's squash racket while playing DATE_TIME (was wearing his glasses, but no goggles). diagnosed with corneal abrasion os, notes floater os since then, but no other apparent injury. still plays at university club occasional floaters \u00ff 1. glaucoma suspect, c/d asymmetry od>os (low suspicion) seen by PERSON rhee in the past tmax 21/22. cct 530/531 (sl thin). no fhx hvf DATE_TIME: full ou hvf DATE_TIME: full ou hvf DATE_TIME: full ou hvf 3/08: full ou stable since DATE_TIME oct DATE_TIME: wnl ou oct DATE_TIME: wnl ou DATE_TIME: wnl ou oct DATE_TIME: wnl ou iop borderline, onh appear stable, will continue to follow. \u00ff 2. mild cataracts, not visually significant -updated glasses prescription last visit for sunglasses (dvo) (current glasses nice too as they are small enough profile he can look under them to read) PERSON shift \u00ff 3. h/o exotropia surgery age DATE_TIME. refractive error - provided updated mrx DATE_TIME DATE_TIME (overminused, will change his squash goggles and possibly pals)",
"gpt4_summary": "58yo with hyperlipidemia, injured by squash racket causing corneal abrasion. Notes occasional floaters. Suspected glaucoma due to c/d asymmetry; low suspicion, borderline IOP. Mild cataracts present.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09752",
"image_path": "slo_fundus_09752.jpg",
"filename": "data_09752.npz",
"report": "Male patient with DM2 presented for a diabetic eye exam. His A1C level is slightly high but better than last visit. He is a low-suspicion glaucoma suspect with normal IOP and mac scan. Reports having contact dermatitis possibly due to mask use.",
"age": 55.92,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "PERSON is a DATE_TIME. male presents DATE_TIME for diabetic eye health exam. dm2 no bdr on exam (DATE_TIME) a1c little high, better than last visit discussed the importance of blood sugar control hemoglobin a1c date value ref range status DATE_TIME 8.4 (h) 4.2 - 5.6 % final comment: hba1c levels 5.7-6.4% represent pre-diabetes, indicating impaired glucose control and an increased risk of developing diabetes. the diagnostic hba1c level for diabetes is 6.5% or greater. hba1c levels <4.2% may indicate a hemoglobinopathy or anemia, and an alternative method is recommended to monitor glucose control. pt reports his a1c is higher than it has ever been low suspicion glaucoma suspect risks include: DM2 IOP WNL OU Tcorr -2, -1 oct rnfl normal ou. gcl thin ou. Mac scan WNL ou. hvf 24-2 full ou instructed pt to investigate ofhx rl dermatitis, mild changes, ?allergic shiner reports he is been going through contact dermatitis from DATE_TIME. works in hospital setting, thinks it's related to 'mask wearing'. does not appear to be contact dermatitis per DATE_TIME's (DATE_TIME) exam has been using 'topic DATE_TIME around the eyelids and around the facial skin (?steroid ointment) -- warned pt to avoid steroidal meds, as they increase risks on ocular health. gave pt seasonal allergy handout recommend at's prn and allergy testing avoid heat/rubbing/allergens avoid visine and other medications that 'get the red out' recommended pt to see dermatology specialist rtc in DATE_TIME for diabetic eye exam by signing my name below, i, PERSON, acting as a scribe, attest that this documentation has been prepared under the direction and in the presence of PERSON, LOCATION DATE_TIME DATE_TIME",
"gpt4_summary": "Male patient with DM2 presented for a diabetic eye exam. His A1C level is slightly high but better than last visit. He is a low-suspicion glaucoma suspect with normal IOP and mac scan. Reports having contact dermatitis possibly due to mask use.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09755",
"image_path": "slo_fundus_09755.jpg",
"filename": "data_09755.npz",
"report": "The patient has high intraocular pressure (30/24, 31/25), indicative of glaucoma, and has responded well to latanoprost. No follow-up needed.",
"age": 61.73,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "initial note: found to have intraocular pressure 30/24 and 31/25 and started on latanoprost with good response. visual field full in LOCATION relevant medications latanoprost (xalatan) 0.005 % ophthalmic solution other relevant orders humphrey visual field - ou - both eyes (completed) oct, optic nerve - ou - both eyes - cirrus; rnfl, gcc (completed) return for no follow up.",
"gpt4_summary": "The patient has high intraocular pressure (30/24, 31/25), indicative of glaucoma, and has responded well to latanoprost. No follow-up needed.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09758",
"image_path": "slo_fundus_09758.jpg",
"filename": "data_09758.npz",
"report": "The clinical note reveals the patient has hypothyroidism, breast cancer, hypertension, thyroid cancer, osteopenia, asthma, heart issues, and glaucoma, among other conditions.",
"age": 77.12,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "mg tab take 1 tablet (20 mg total) by mouth DATE_TIME. simvastatin (zocor) 10 mg tablet take 1 tablet (10 mg total) by mouth nightly. facility administered medications iopamidol (isovue-370) 76 % injection 100 ml inject 100 ml into the vein once as needed for pre procedure/treatment (for ct simulation). condition list as of DATE_TIME hypothyroidism breast cancer hypertensive disorder malignant neoplasm of thyroid gland hyperlipidemia osteopenia gastroesophageal reflux disease asthma paroxysmal atrial fibrillation advanced directives, counseling/discussion h/o arthroscopy of knee glaucoma routine adult health maintenance hernia acquired absence of organ, lung normal tension glaucoma of both eyes atrial flutter atrial fibrillation elevated cholesterol hypertension pain of hand heart murmur asthma exacerbation bone metastasis results summary immunizations administered on date of encounter - DATE_TIME none",
"gpt4_summary": "The clinical note reveals the patient has hypothyroidism, breast cancer, hypertension, thyroid cancer, osteopenia, asthma, heart issues, and glaucoma, among other conditions.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09762",
"image_path": "slo_fundus_09762.jpg",
"filename": "data_09762.npz",
"report": "70 y.o. male patient diagnosed with glaucoma, has pseudophakia, immature cataract, retinal detachment repair with scleral buckle and vitreous debris. Referred to glaucoma service, iop stable.",
"age": 70.78,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "a 70 y.o. white, non-hispanic male was evaluated and diagnosed with glaucoma. 70 y.o. male: \u00ff\u00ff 1. pseudophakia od (dr. PERSON) s/p yag capsulotomy DATE_TIME, doing well \u00ff\u00ff 2. immature cataract os not very visually significant to patient, wears cl in os \u00ff\u00ff 3. s/p retinal detachment repair with scleral buckle ou os in DATE_TIME od: scleral buckle placement, \u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ffcryoretinopexy, drainage of \u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ff\u00ffsubretinal fluid, od DATE_TIME (dr. PERSON) retina attached now vitreous debris od, stable floaters, rare flashes \u00ff\u00ff 4. glaucoma suspect iop ok (16/17- a little higher than prior values) large cups was referred to glaucoma service in the past, seen by PERSONon oct rnfl DATE_TIME: borderline DATE_TIME: mild progression od sup thinning, os inferior thinning DATE_TIME DATE_TIME: sup thinning od, normal os oct rnfl DATE_TIME: od: worsening sup thinning and new inferior thinning/ os: normal hvf DATE_TIME: dense nasal defect os (described in glaucoma note previously, images of old hvf not available in synergy to compare) hvf DATE_TIME: stable hvf DATE_TIME: stable hvf DATE_TIME: stable hvf defect os likely related to previous retinal detachment and residual retinal scarring \u00ff pachy PERSON: true iop about the same as measured rec: - start timolol bid od follow-up for iop check",
"gpt4_summary": "70 y.o. male patient diagnosed with glaucoma, has pseudophakia, immature cataract, retinal detachment repair with scleral buckle and vitreous debris. Referred to glaucoma service, iop stable.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09766",
"image_path": "slo_fundus_09766.jpg",
"filename": "data_09766.npz",
"report": "The patient is suspected to have primary open-angle glaucoma (POAG), currently using Lumigan. Gonioscopy shows open angles. It's mentioned the patient may have pre-perimetric glaucoma, with extra follow-up required.",
"age": 62.68,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "# poag suspect, here for second opinion, prev seen PERSON arrives on lumigan , no fhx, no trauma, no steroids ttarget: / , tmax:18 ou cct: 536 / 545 gonioscopy: open to cbb ou rnfl oct borderline ou, watch od vf full ou anesthesiologist plan: vf DATE_TIME likely stable ou -- difficult due to myopic nerves may be pre-perimetric glaucoma but will need to follow to assess for progression continue monitoring off drops to have PERSON done soon , discussed rba of multifocal lens with patient, he will do this locally will also plan to follow with ophthalmologic locally for DATE_TIME or bi-annual testing if any concern for worsening, will return to LOCATION",
"gpt4_summary": "The patient is suspected to have primary open-angle glaucoma (POAG), currently using Lumigan. Gonioscopy shows open angles. It's mentioned the patient may have pre-perimetric glaucoma, with extra follow-up required.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09768",
"image_path": "slo_fundus_09768.jpg",
"filename": "data_09768.npz",
"report": "Female patient with low suspicion for glaucoma. Risks include crowded optic disc and family history of glaucoma. Normal rnfl and gcl. Nonspecific HVF 24-2 changes. Also has history of stye and macular degeneration in family.",
"age": 29.67,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "PERSON is a DATE_TIME. female low suspicion glaucoma suspect risks include: PERSON (paternal side of family), crowded optic disc dad had trabeculectomy in DATE_TIME PERSON. PERSON DATE_TIME (DATE_TIME) rnfl and gcl normal ou hvf 24-2 (DATE_TIME) nonspecific changes ou showed pt glaucoma diagrams h/o stye rul pt can treat with warm compresses fhx of macular degeneration pt reports this on her maternal side of family f/u in DATE_TIME for hvf 24-2, oct, NRP, ar/refract",
"gpt4_summary": "Female patient with low suspicion for glaucoma. Risks include crowded optic disc and family history of glaucoma. Normal rnfl and gcl. Nonspecific HVF 24-2 changes. Also has history of stye and macular degeneration in family.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09771",
"image_path": "slo_fundus_09771.jpg",
"filename": "data_09771.npz",
"report": "The patient has stable blepharitis/dry eyes and somewhat visually significant cataracts. She is suspect for glaucoma with an increased cup to disc ratio, ocular hypertension, thin pachymetry, and slightly higher intraocular pressure. The patient is on treatment with latanoprost for glaucoma suspect/ocular hypertension, which was not taken recently due to lack of supply. She also has a refractive error and has lost her glasses.",
"age": 84.36,
"gender": "female",
"race": "white",
"ethnicity": "hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "last seen by me DATE_TIME. 1. blepharitis/dry eyes ou: stable - continue warm compresses as needed - continue flax seed oil - continue preservative free artificial tears as needed 2. cataracts ou: somewhat visually significant, but still able to do activities without difficulty. she does not drive. - observe for now but is moving toward need for surgery in DATE_TIME. refractive error: changed - lost glasses - give new rx for glasses 4. increased cup to disc ratio, glaucoma suspect/ocular hypertension: pachymetry thin (522, 515), PERSON pressure 22, DATE_TIME, gonio open ou; intraocular pressure slightly higher DATE_TIME but has not been taking drops, large nerves ou on imaging without progressive thinning. visual fields have been nonspecific ou with lid artifact DATE_TIME. she has not been taking the latanoprost - ran out. - restart latanprost ou qhs - return for pressure check in DATE_TIME dfe: 5/22 vf: 5/22 oct: 5/22 gonio: 3/13 tmax: 24, 22 cct: 522,515 fhx: unknown",
"gpt4_summary": "The patient has stable blepharitis/dry eyes and somewhat visually significant cataracts. She is suspect for glaucoma with an increased cup to disc ratio, ocular hypertension, thin pachymetry, and slightly higher intraocular pressure. The patient is on treatment with latanoprost for glaucoma suspect/ocular hypertension, which was not taken recently due to lack of supply. She also has a refractive error and has lost her glasses.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09773",
"image_path": "slo_fundus_09773.jpg",
"filename": "data_09773.npz",
"report": "The 47-year-old male patient, who once had micro-hyphema which has now resolved, is considered a glaucoma suspect due to physiologic cupping with large nerves. However, OCT nerve is normal. Mother may have had glaucoma. Also suffers from allergic conjunctivitis.",
"age": 47.95,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "47 y.o. male here for DATE_TIME eye exam # micro-hyphema od (DATE_TIME) - 2/2 bungee cord 4/14, resolved, iop stable # retina PERSON resolved \u00ff\u00ff # glaucoma suspect ou - likely physiologic cupping in setting of large nerves ou - ?fh mom glaucoma (vs cataract). pt not sure - oct nerve DATE_TIME: normal ou - pachy: 556/569 - gonio DATE_TIME: pigmented tm, open to cbb all quadrants, no angle recession, no pas - hvf DATE_TIME: reliable and full ou - disc photos DATE_TIME # allergic conjunctivitis >zaditor prn rtc 1 year: coe, hvf, oct nerve",
"gpt4_summary": "The 47-year-old male patient, who once had micro-hyphema which has now resolved, is considered a glaucoma suspect due to physiologic cupping with large nerves. However, OCT nerve is normal. Mother may have had glaucoma. Also suffers from allergic conjunctivitis.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09774",
"image_path": "slo_fundus_09774.jpg",
"filename": "data_09774.npz",
"report": "55-year-old female patient with visual changes, notably a black spot in her eye. She has large cup-to-disc ratio, but normal intraocular pressure. No glaucoma detected. No history of cancer or recent flu-like illnesses. She was referred to Retina and Oral Medicine.",
"age": 55.36,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "55f referred from ed with visual changes os (black spot os, amsler grid changes) found to have very large c:d ou (normal iop DATE_TIME) \u00ff plan #visual changes os mac oct DATE_TIME: od normal foveal contour, os with loss of outer retinal layers nasal to fovea no tamoxifen no plaquenil no recent flu-like illnesses no cancer history recent illness history: DATE_TIME when she was sick with a cold and after a course of antibiotic she developed 'thrush'. she was prescribed 3 different type of antifungal medications (she did not respond to the first course). seen by dr. PERSON for glossitis- referred to oral medicine for this where she is now being followed and has occasionally bee on steroids refer to retina # large c/d ratio - longstanding per patient - iop ok - rnfl oct full rims ou - hvf reliable and full ou - observe plan: followup next available with retina for retinal findings os followup annually with me-- disc photos next visit and cct _____________________ PERSON, md, mph comprehensive ophthalmology LOCATION",
"gpt4_summary": "55-year-old female patient with visual changes, notably a black spot in her eye. She has large cup-to-disc ratio, but normal intraocular pressure. No glaucoma detected. No history of cancer or recent flu-like illnesses. She was referred to Retina and Oral Medicine.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09775",
"image_path": "slo_fundus_09775.jpg",
"filename": "data_09775.npz",
"report": "Patient has no diabetes. Pre-op medications include topical and antibiotic. IOP check and HVF OU scheduled. If IOP persists above goal, MP CPC or restart suggested. No direct mention of glaucoma.",
"age": 73.06,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "implants/special equipment needed -- *** preferred anesthesia -- *** diabetic -- no pre-op medications -- topical LOCATION and antibiotic DATE_TIME prior to surgery -rtc in DATE_TIME with iop check and hvf ou, sooner prn. if iop persistently above goal on LOCATION/steroids in the future and especially if hvf worsens od in the future, we can consider mp cpc (mp probe alone) or restarting PERSON. the information above was documented by PERSON as a scribe for PERSON on DATE_TIME .",
"gpt4_summary": "Patient has no diabetes. Pre-op medications include topical and antibiotic. IOP check and HVF OU scheduled. If IOP persists above goal, MP CPC or restart suggested. No direct mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09777",
"image_path": "slo_fundus_09777.jpg",
"filename": "data_09777.npz",
"report": "The patient is on Benicar (40mg) and Prednisone (80mg). They are referred to Ophthalmology with orders for multiple eye tests, including for glaucoma. No immunizations were given.",
"age": 65.59,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "(benicar) 40 mg tablet take 40 mg by mouth DATE_TIME. prednisone (deltasone) 20 mg tablet take 4 tablets (80 mg total) by mouth DATE_TIME. your orders normal orders this visit ambulatory referral to Institution ophthalmology color fundus photography - ou - both eyes creatinine/PERSON visual field - ou - both eyes oct, optic nerve - ou - both eyes - optovue oct, retina - ou - both eyes - cirrus; retina future labs/procedures complete by expires mri brain DATE_TIME DATE_TIME mri face DATE_TIME, retina - ou - both eyes - cirrus; retina as directed DATE_TIME results summary results immunizations administered on date of encounter - DATE_TIME none patient gateway activation information your account is ready to use. LOCATION.",
"gpt4_summary": "The patient is on Benicar (40mg) and Prednisone (80mg). They are referred to Ophthalmology with orders for multiple eye tests, including for glaucoma. No immunizations were given.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09778",
"image_path": "slo_fundus_09778.jpg",
"filename": "data_09778.npz",
"report": "78 y.o. black, non-hispanic female diagnosed with glaucoma.",
"age": 78.9,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "other",
"maritalstatus": "married or partnered",
"note": "a 78 y.o. black, non-hispanic female was evaluated and diagnosed with glaucoma. already have a account, please sign in with your username and password. \u0007",
"gpt4_summary": "78 y.o. black, non-hispanic female diagnosed with glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09783",
"image_path": "slo_fundus_09783.jpg",
"filename": "data_09783.npz",
"report": "The 65-year-old male is suspected of having glaucoma due to an enlarged c/d ratio. He has hyperopia and presbyopia, enlarged nuclear and cortical cataract, and a posterior vitreous detachment. His vision is 20/20 in the right eye and 20/25 in the left.\n",
"age": 65.97,
"gender": "male",
"race": "asian",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "married or partnered",
"note": "65 y.o. male referred by PERSON for glaucoma evaluation # glaucoma suspect ou secondary to enlarged c/d ratio os>od - no fh glc - cct 520's - tmax 16 ou, PERSON: wide open to cbb - cups large os>od c/w large DATE_TIME rnfl and gcc full ou but possible relative blunting superiorly os within the green - hvf has been unreliable: in DATE_TIME, possible LOCATION, DATE_TIME, cloverleaf ou # nuclear and cortical cataract ou - c/o DATE_TIME driving - bcva od: 20/20; os: 20/25 - pt ed, will monitor # hyperopia ou with presbyopia - per dr jiang # posterior vitreous detachment os - rd precautions plan DATE_TIME reassuring findings, reviewed with patient - monitor off drops - monitor os for progression in the green DATE_TIME iop hvf ou with careful coaching during hvf",
"gpt4_summary": "The 65-year-old male is suspected of having glaucoma due to an enlarged c/d ratio. He has hyperopia and presbyopia, enlarged nuclear and cortical cataract, and a posterior vitreous detachment. His vision is 20/20 in the right eye and 20/25 in the left.\n",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09785",
"image_path": "slo_fundus_09785.jpg",
"filename": "data_09785.npz",
"report": "Patient discussed pseudoexfoliation (pxf), cataracts and their connection. Follow-up appointment scheduled for an IOP check and disc photos. No mention of glaucoma.",
"age": 60.63,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "we discussed pxf, cataracts, and their connection (see above). -rtc in DATE_TIME with iop check and disc photos ou, sooner prn. the information above was documented by PERSON as a scribe for PERSON on DATE_TIME.",
"gpt4_summary": "Patient discussed pseudoexfoliation (pxf), cataracts and their connection. Follow-up appointment scheduled for an IOP check and disc photos. No mention of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09787",
"image_path": "slo_fundus_09787.jpg",
"filename": "data_09787.npz",
"report": "The patient has glaucoma, worse in the right eye with hard to control pressures. His vision loss is due to glaucoma despite a tube shunt surgery. He hasn't seen a glaucoma doctor in a while and has been on steroids.",
"age": 77.99,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "glaucoma eval (cct, gonio, hvf 24-2, and oct rnfl). *pt reports that right eye has much more difficult to control pressures *he is here for a second opinion after losing vision right eye in DATE_TIME after a tube shunt surgery. however, his intraocular pressure 'hovers around 28-29' per pt so it is likely that the glaucoma took his vision. *he has not seen a glaucoma doctor for DATE_TIME since his last surgery in DATE_TIME. this is likely why he has been on pf bid ou steroids for DATE_TIME. stop pred LOCATION bid ou *has been using over DATE_TIME continue simbrinza bid ou start latanoprost qhs both eyes last dilated exam: next visit DATE_TIME rnfl: DATE_TIME last visual field: DATE_TIME baseline disc photos: next visit return to glaucoma clinic DATE_TIME with gvf right eye, dfe, and dilated optical coherence tomography mac, and disc photos *sent message to PERSON to get his prior notes from dr. PERSON in PERSON acting as scribe for dr. PERSON on DATE_TIME.",
"gpt4_summary": "The patient has glaucoma, worse in the right eye with hard to control pressures. His vision loss is due to glaucoma despite a tube shunt surgery. He hasn't seen a glaucoma doctor in a while and has been on steroids.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09788",
"image_path": "slo_fundus_09788.jpg",
"filename": "data_09788.npz",
"report": "73-year-old female has migraines with aura and right eye blurriness. She has a past medical history of psoriasis and Crohn's disease and is here for follow-up. Noticed a decrease in vision. Glaucoma is suspected.",
"age": 73.49,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "73 yo f here for fu having migraines with aura. noticing r eye blurriness. referred by son in law (PERSON) pmhx: psoriasis, crohn's (not active) sees a doctor in ct #s/p ce/pciol os, zcb00 +22.0 DATE_TIME # s/p cataract extraction/iol od DATE_TIME - noticing progressive blurring - pco could be contributing - schedule yag cap #opacification of the posterior capsule discussed opc and that it is the cause of decrease vision and lifestyle complaint. risks benefits and alternatives of surgery discussed with the patient. risk of floaters, retinal detachment and retinal swelling discussed with patient. fu DATE_TIME post yag. #dry eye ou with mgd/reduced tf not using omega 3 fa, restasis or systane currently restart systane 2-3x/day ou, hc bid, omega-3 fa can add restasis back if dry eye not improved # dry amd ou very mild rpe mottling on exam - continue areds2 oct no edema #glaucoma suspect with mild increased c/d -oct DATE_TIME without thinning -hvf DATE_TIME poor reliability due to high fl mod depression inferiorly od; nonspecific changes os -overall does not correlate with oct although one wedge of mod thinning od sn which has improved since last test will repeat hvf od after yag #eczema on lids and face NRP dermatologist # migraines with aura - having DATE_TIME verapamil, which has decreased episodes - mri/mra brain normal per pt (ordered by neuro) - following with milford neurology - dr. PERSON. has f/u in DATE_TIME. schedule yag cap od repeat hvf od after yag",
"gpt4_summary": "73-year-old female has migraines with aura and right eye blurriness. She has a past medical history of psoriasis and Crohn's disease and is here for follow-up. Noticed a decrease in vision. Glaucoma is suspected.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09799",
"image_path": "slo_fundus_09799.jpg",
"filename": "data_09799.npz",
"report": "The patient is a 63-year-old female suspected of glaucoma due to cup to disc ratio, with narrow angles noted in both eyes. She also has mild cataracts in both eyes. No glaucoma medication intolerances.",
"age": 63.92,
"gender": "female",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "refraction (auto) sphere cylinder axis right LOCATION -0.50 095 left +1.75 -1.00 095 assessment and plan first seen by dr. PERSON on DATE_TIME glaucoma medication intolerances: none target iop: DATE_TIME, tmax: 22 / 21 central corneal thickness: 603 / 594 gonioscopy: (b)d20p 1+, no pas ou retinal nerve fiber layer, right eye: no thinning retinal nerve fiber layer, left eye: no thinning visual fields, right eye: full visual fields, left eye: full family history: none steroids: none trauma: none asthma/copd: none other medical history and problems: generally healthy assessment/plan: 63 y.o. female referred by dr. PERSON for narrow angles # anatomic narrow angle/primary angle closure suspect, both eyes # glaucoma suspect due to cup to disc ratio, right > left eye - iop acceptable ou, angles borderline - return in DATE_TIME for iop check, dilate with tropicamide 0.5% # cataract, both eyes - mild, not visually significant, monitor PERSON scribing for dr. PERSON i attest that i was present while this encounter was recorded and agree that the information entered by my scribe and updated by me is complete and accurate. PERSON, md",
"gpt4_summary": "The patient is a 63-year-old female suspected of glaucoma due to cup to disc ratio, with narrow angles noted in both eyes. She also has mild cataracts in both eyes. No glaucoma medication intolerances.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09800",
"image_path": "slo_fundus_09800.jpg",
"filename": "data_09800.npz",
"report": "The patient underwent visual tests for both eyes and has asthma, depression, diabetes type 2, reflux disease, hypertension, and ankle pain. No mention of glaucoma found.",
"age": 61.63,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "legally separated",
"note": "color fundus photography - ou - both eyes humphrey visual field - ou - both eyes oct, optic nerve - ou - both eyes - cirrus; retina, optic disc; rnfl, gcc, 5 line raster condition list as of DATE_TIME asthma depressive disorder type 2 diabetes mellitus gastroesophageal reflux disease hypertensive disorder ankle pain results summary immunizations administered on date of encounter",
"gpt4_summary": "The patient underwent visual tests for both eyes and has asthma, depression, diabetes type 2, reflux disease, hypertension, and ankle pain. No mention of glaucoma found.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09802",
"image_path": "slo_fundus_09802.jpg",
"filename": "data_09802.npz",
"report": "82 y.o. male dentist has severe neck problems, nuclear cataract os nuclear sclerosis, pseudophakia od iol stable, pigment macular changes os, blepharitis ou, posterior vitreous detachment os, and ocular hypertension ou. No glaucoma detected.",
"age": 82.8,
"gender": "male",
"race": "white",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "married or partnered",
"note": "82 y.o. male\u00ffretired dentist, here for follow up: very difficult slit lamp exam, severe neck problems, cannot reach slit lamp for more than DATE_TIME at a time. \u00ff 1. type ii dm no evidence of diabetic retinopathy. patient was advised to maintain tight blood sugar and blood pressure control. mild non-proliferative diabetic retinopathy in the past. follow-up with pcp for glycemic control. 2. nuclear cataract os nuclear sclerosis, not very visually significant observation for now ?? 3. pseudophakia od iol stable, capsule clear ? 4. pigment macular changes os not visually significant monitor amsler grid DATE_TIME drusen ou rec: - refer to retina \u00ff\u00ff 5. blepharitis ou warm compresses, lid hygiene with baby shampoo bid, use at prn for symptoms of dry eye. 6. posterior vitreous detachment os ?retinal detachment precautions were reviewed with the patient in detail including increase in and/or change in floaters, worsening flashing lights, and curtains or shadows? 7. ocular hypertension ou iop DATE_TIME: 20/22 iop DATE_TIME: 24/25 (22/24 measured by me) iop DATE_TIME: 19/19 (applanation by me) iop DATE_TIME: 21/22 oct rnfl DATE_TIME: normal ou hvf DATE_TIME: inferior central scotoma ou, borderline reliability optic nerves look ok cont latanoprost qhs ou",
"gpt4_summary": "82 y.o. male dentist has severe neck problems, nuclear cataract os nuclear sclerosis, pseudophakia od iol stable, pigment macular changes os, blepharitis ou, posterior vitreous detachment os, and ocular hypertension ou. No glaucoma detected.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09804",
"image_path": "slo_fundus_09804.jpg",
"filename": "data_09804.npz",
"report": "The patient shows no symptoms of infection or comorbidities during a pre-visit screening. There is no mention of glaucoma.",
"age": 49.08,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "PERSON pre-visit symptom screening date: DATE_TIME symptoms fever: no cough: no mild shortness of breath: no sore throat: no muscle aches: no nasal congestion: no loss of smell/taste: no atypical symptom concerning for PERSON: no concerning symptoms or comorbidities: no additional symptom comments:not answered date of symptom onset: not answered pre-visit screening in DATE_TIME, has the patient had a positive or pending DATE_TIME test outside of Institution? no in DATE_TIME, has the patient spent DATE_TIME within 6 feet of anyone currently infected with DATE_TIME? no",
"gpt4_summary": "The patient shows no symptoms of infection or comorbidities during a pre-visit screening. There is no mention of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09806",
"image_path": "slo_fundus_09806.jpg",
"filename": "data_09806.npz",
"report": "62 yo woman with hyperlipidemia, depression, anxiety, panic attacks, vernal irritation with pollen has borderline increased eye pressure, but thick corneas, no glaucoma. History of dry eyes, allergic conjunctivitis, choroidal nevus OS.",
"age": 62.99,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "62 yo woman with history of hyperlipidemia, depression, anxiety, panic attacks vernal irritation with pollen. \u00ff 1. incr'd c/d ou (borderline elevated iop but thick corneas) -tmax 22/22. cct DATE_TIME (thick). no fhx glaucoma gonio DATE_TIME: cbb 360' ou hvf DATE_TIME: full ou (enlarged bs os) hvf DATE_TIME: full ou hvf DATE_TIME: full ou oct DATE_TIME: wnl ou, stable DATE_TIME: wnl ou oct DATE_TIME: PERSON ou, stable DATE_TIME: wnl ou >> will follow. \u00ff 2. history of dry eyes and allergic conjunctivitis -stopped wearing ctl due to dryness -symptoms now well controlled -also uses opcon-a sparingly >> continue using systane qday prn >> advised zaditor for itching (instead of opcon-a) \u00ff 3. pvd os maintain rd precautions \u00ff 4. choroidal nevus os -updated rx DATE_TIME DATE_TIME as backup (prefers LOCATION) LOCATION pgy4 i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow. i have reviewed the resident/fellow's notes and made any necessary changes.",
"gpt4_summary": "62 yo woman with hyperlipidemia, depression, anxiety, panic attacks, vernal irritation with pollen has borderline increased eye pressure, but thick corneas, no glaucoma. History of dry eyes, allergic conjunctivitis, choroidal nevus OS.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09807",
"image_path": "slo_fundus_09807.jpg",
"filename": "data_09807.npz",
"report": "51 y.o. white, non-hispanic female. No diagnosis of glaucoma. No procedures listed.",
"age": 51.96,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "a 51 y.o. white, non-hispanic female with no diagnosis of glaucoma. this patient. this time excludes any listed procedures.",
"gpt4_summary": "51 y.o. white, non-hispanic female. No diagnosis of glaucoma. No procedures listed.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09809",
"image_path": "slo_fundus_09809.jpg",
"filename": "data_09809.npz",
"report": "Patient had a fall & car accident. Doesn't drive anymore. Plan includes controlling intraocular pressure (IOP) in both eyes to \u2264 15 mmHg. Current IOP is 21 mmHg, borderline high, indicative of possible glaucoma. Will pursue topical therapy.",
"age": 87.65,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "still works for an insurance company. his children went to harvard undergraduate. his daughter is a dermatologist. he had a fall while golfing in LOCATION; he also had a car accident on DATE_TIME, and he doesn't drive anymore. attending's plan: -goal intraocular pressure less than or equal to 15 mmhg, right eye. -goal intraocular pressure less than or equal to 15 mmhg, left eye. -iop above goal ou on DATE_TIME on PERSON. -continue PERSON => rx sent to pharmacy on DATE_TIME. -start brimonidine bid ou. -instructions written/typed/printed out for patient (see table/details under patient instructions). -emphasized adherence to medication regimen. -follow-up with dr. PERSON for retina care. -retinal detachment precautions were reviewed with the patient. -monocular precautions discussed: patient should wear polycarbonate glasses at all times to protect seeing eye. -preservative-free artificial tears as needed. -long discussion with patient on DATE_TIME: he may have hvf defects that correspond to onh appearance/oct rnfl, and he is monocular. his iop is borderline at 21 mmhg. i recommended therapy ou to lower iop. pros/cons discussed in detail including possibility of permanent eye color change; patient elected to pursue topical therapy. i also recommended bp medications be taken in DATE_TIME (if pcp thinks it is safe). he denied snoring or sleep apnea s/sx on a consistent basis. -rtc in DATE_TIME for iop check, dilation, oct rnfl/gcc, and disc photos ou, sooner prn. the information above was documented by PERSON as a scribe for PERSON on DATE_TIME.",
"gpt4_summary": "Patient had a fall & car accident. Doesn't drive anymore. Plan includes controlling intraocular pressure (IOP) in both eyes to \u2264 15 mmHg. Current IOP is 21 mmHg, borderline high, indicative of possible glaucoma. Will pursue topical therapy.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09812",
"image_path": "slo_fundus_09812.jpg",
"filename": "data_09812.npz",
"report": "69 yo woman has a history of hypertension, hypothyroidism, and bipolar disorder. Reports declining vision due to cataract, myopic degeneration and glaucoma. Might be considered for combined glaucoma/cataract surgery. High risk for glaucoma (c/d os>od).",
"age": 69.82,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "69 yo woman with history of htn, hypothyroidism, bipolar disorder new patient DATE_TIME DATE_TIME. has been followed by PERSON PERSON. reports that vision has been gradually declining vision at all distances ou over DATE_TIME. 1. cataract ou - likely slightly contributing to decline in vision, vision worsens by a few lines with bat, however myopic degeneration and glaucoma likely more contributory >> mrx DATE_TIME in polycarbonates >> will refer for consideration of combined glaucoma/cataract surgery in future 2. glaucoma (c/d os>od), high risk tmax 16/16 uncle with glaucoma, but also had corneal transplant DATE_TIME: is thinning ou, myopic nerve hvf DATE_TIME: od global depression. PERSON, scattered superior losses >> DATE_TIME: hvf and onh concerning, never had LOCATION will start latanoprost ou qhs (practiced PERSON admin in clinic). glaucoma referral 3. myopic degeneration od>os, staphyloma ou, central macular schisis os se od -15.75 and os -12.50 oct macula DATE_TIME: od: myopic appearance, loss of foveal contour, flat, os: temporal macular retinoschsis >> retina evaluation 4. dermatochalasis ou > observe k PERSON i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow. i have reviewed the resident/fellow's notes and made any necessary changes.",
"gpt4_summary": "69 yo woman has a history of hypertension, hypothyroidism, and bipolar disorder. Reports declining vision due to cataract, myopic degeneration and glaucoma. Might be considered for combined glaucoma/cataract surgery. High risk for glaucoma (c/d os>od).",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09814",
"image_path": "slo_fundus_09814.jpg",
"filename": "data_09814.npz",
"report": "Patient has optic papillitis, outer retinitis, & abnormal spinal fluid possibly linked to myxopapillary ependymoma. Visual acuity 20/20. Inflammatory retinal/choroidal lesions found in right eye. No mention of glaucoma.",
"age": 54.72,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "optic papillitis and outer retinitis of unclear etiology. during the workup she was found to have abnormal spinal fluid which in retrospect may have been related to the myxopapillary ependymoma which became symptomatic as the prednisone was tapered. DATE_TIME on exam the acuities are 20/20 od (distance) and 20/20 os (near). there is no dyschromatopsia or relative apd. visual field testing shows a new inferior nasal constriction od; os there is central and inferior depression with a deep paracentral defect supratemporally. overall the left visual field is stable. the right optic nerve and retina were previously normal, but DATE_TIME there is mild hyperemic disc swelling with peripapillary retinal folds, and numerous deep white retinal lesions in the macula and periphery sparing nasally. in the left eye there is resolved edema with sectoral temporal disc atrophy and nfl loss in the inferior macula. i did not appreciate the prior seen deep retinal lesions in the left eye. ms. PERSON now has PERSON and likely inflammatory outer retinal/choroidal lesions in the right eye. it is likely to be an inflammatory process, and it is unclear if it is related to the ependymoma. i started her on prednisone 60 mg DATE_TIME to take until she sees dr. LOCATION DATE_TIME. she does not want systemic steroids but was willing to consider a periocular injection until other non-steroidal immune modulating therapy becomes effective. \u00ff plan: 1. prednisone 60 mg DATE_TIME. dr. PERSON on DATE_TIME. PERSON, LOCATION. \u00ff \u00ff note: greater than half of this DATE_TIME visit was spent counseling the patient on the medical condition or coordinating care. \u00ff",
"gpt4_summary": "Patient has optic papillitis, outer retinitis, & abnormal spinal fluid possibly linked to myxopapillary ependymoma. Visual acuity 20/20. Inflammatory retinal/choroidal lesions found in right eye. No mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09817",
"image_path": "slo_fundus_09817.jpg",
"filename": "data_09817.npz",
"report": "34 y/o male physician, glaucoma suspect due to enlarged c/d ratio. No known family history of glaucoma or history of long-term steroid use. IOP mid teens. Also has myopia, astigmatism, and history of seasonal allergic conjunctivitis/rhinitis. No need for intervention.",
"age": 33.85,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "34 y/o male physician at boston healthcare for the homeless. presents here DATE_TIME for iop check and repeat hvf. last seen on DATE_TIME for comprehensive eye exam and cl exam. \u00ff assessment: 1. glaucoma suspect ou enlarged c/d ratio ou. iop mid teens. no known fhx of glaucoma. no hx of long-term steroid use. cct DATE_TIME: 537/541 gonio DATE_TIME: open ou oct-rnfl DATE_TIME: normal od, borderline focal thinning superiorly os DATE_TIME: borderline focal thinning superiorly ou DATE_TIME: borderline focal thinning superiorly ou hvf DATE_TIME: essentially full ou DATE_TIME: essentially full ou iop DATE_TIME 14/14. no indication for intervention at present. continue to monitor at this time. 2. myopia, astigmatism ou latest refraction on DATE_TIME. only had minor rx changes. specs rx dispensed in case new glasses wanted, but not necessary. 3. soft contact lens wearer no need for toric correction. cl rx last dispensed on DATE_TIME for PERSON oasys hydraluxe DATE_TIME. 4. hx of seasonal allergic conjunctivitis and rhinitis takes PERSON and uses PERSON prn. doing fine at the moment. 5. PERSON ou mild overall. currently asymptomatic. no longer doing warm compresses or lid hygiene/scrubs. 6. choroidal PERSON. stable benign appearance per latest dfe on DATE_TIME. management/plan: reviewed proper cl hygiene/care including avoiding sleeping/swimming/showering in lenses and discarding them DATE_TIME after each use. continue zaditor bid ou and PERSON prn for seasonal allergic conjunctivitis and rhinitis. recommended warm compresses, lid hygiene/scrubs, and artificial tears prn for ocular comfort. return in DATE_TIME for DATE_TIME comprehensive eye exam, cl exam, and repeat DATE_TIME. rtc sooner prn.",
"gpt4_summary": "34 y/o male physician, glaucoma suspect due to enlarged c/d ratio. No known family history of glaucoma or history of long-term steroid use. IOP mid teens. Also has myopia, astigmatism, and history of seasonal allergic conjunctivitis/rhinitis. No need for intervention.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09823",
"image_path": "slo_fundus_09823.jpg",
"filename": "data_09823.npz",
"report": "Patient suspected of normal tension glaucoma due to increased cup/disc ratio. Pachymetry 540 ou and normal pressure. Family history of glaucoma. Ocular migraines noted. OCT imaging reveals borderline thinning.",
"age": 57.47,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "1. normal tension glaucoma suspect based on increased cup/disc ratio ou: pachymetry 540 ou outside record, pressure has always been in normal range per patient, ok today too, + fh: father with glaucoma on multiple gtt, +history of ocular migraine. visual field DATE_TIME reliable but shows a new inferior defect os, oct imaging shows borderline thinning inferior and superior od and thinning sup os. this corresponds to the visual field test DATE_TIME. -repeat humphrey visual field DATE_TIME is normal od, nonspecific defect os - continue monitoring without drops - follow up in DATE_TIME with rnfl oct dfe: 2/16 vf: 5/16 oct: 2/16 gonio: 4/11 tmax: ?17 ou cct: 540 ou fhx: yes 2. contact wearer: stopped using them due to discomfort, ahppy with just glasses now 3. refractive: sl change - rx given for new glasses 3. corneal scars ou: benign, look like PERSON's nodules - lid hygiene 4. lattice os: benign, no frank breaks - retinal detachment warnings 5. ptosis ou: stable, does not wish for surgical correction at this time - observe",
"gpt4_summary": "Patient suspected of normal tension glaucoma due to increased cup/disc ratio. Pachymetry 540 ou and normal pressure. Family history of glaucoma. Ocular migraines noted. OCT imaging reveals borderline thinning.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09825",
"image_path": "slo_fundus_09825.jpg",
"filename": "data_09825.npz",
"report": "Patient with primary open angle glaucoma in both eyes. Current drugs (Timolol, Dorzolamide, Brimonidine) are insufficient. Allergic to Lantanoprost. Requesting Netarsudil for control, to prevent further vision loss.",
"age": 83.13,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "to whom it may concern, i am writing to obtain prior authorization for my patient PERSON (dob DATE_TIME) for netarsudil 0.02% (rhopressa) eye drops. as you know this patient has primary open angle glaucoma in both eyes. this patient's glaucoma is sub-optimally controlled despite already being on maximum other glaucoma medications including the following: - timolol 0.5%/dorzolamide 2% (cosopt) - brimonidine 0.2% they have allergies or have failed the following medications: - latanoprost 0.005% (xalatan) the patient has tried a sample of netarsudil 0.02% (rhopressa) in both eyes, which has improved their intraocular pressure control and in my professional opinion, prevented vision loss. PERSON is at risk of losing more vision and becoming blind if their condition is not well controlled. i urge you to authorize netarsudil 0.02% (rhopressa) eye drops as soon as possible. if they cannot obtain these medications, the next step for them is to undergo additional eye surgery, which has been shown to be not only extremely costly to the health care system but also not ideal for their clinical care. thank you for your understanding. please feel free to contact me for any questions. sincerely, PERSONLOCATION, md",
"gpt4_summary": "Patient with primary open angle glaucoma in both eyes. Current drugs (Timolol, Dorzolamide, Brimonidine) are insufficient. Allergic to Lantanoprost. Requesting Netarsudil for control, to prevent further vision loss.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09831",
"image_path": "slo_fundus_09831.jpg",
"filename": "data_09831.npz",
"report": "The patient is a suspect for glaucoma based on cup to disc ratio and is on glaucoma medication, timolol. They exhibit perifoveal cystic fluid in the right eye, and retinal thinning in both, with no notable family history of glaucoma.",
"age": 39.41,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "e/o pdr - oct mac DATE_TIME: perifoveal cystic fluid od, retinal thinning ou >> maintain good glucose, bp, cholesterol control # cataract ou - very mild, early - given hx of ppv, will monitor more closely # glaucoma suspect - based on c/d - glaucoma meds: timolol qam ou - fhx: none - glauc drug allergies: none - iop 15/14 - tmax (DATE_TIME) 16/30 - gonio (DATE_TIME): open to ss 360 ou, no nvi/nva - pachy (DATE_TIME): 595/564 - hx eye surg or lasers: s/p ppv ou, PERSON ou hvf DATE_TIME: reliable od only, od sup nasal and other focal defects; os unable hvf DATE_TIME: mod reliable od, reliable os; od w nonspecific periph changes, os w inferior > sup nasal step DATE_TIME: od thinning sup and PERSON, os poor scan 2/2 vit heme DATE_TIME: od thinning sup and PERSON, os thinning sup (worsened on this scan) DATE_TIME: od thinning sup, os borderline thinning sup >> stable changes on hvf and oct rnfl (mild fluctuation test to test). may be 2/2 laser and dmi >> continue timolol qam ou. # refractive error/myopia >> mrx provided rtc 6 mo dilate mrx oct rnfl (hvf os only if vision improved) PERSON, md, mph Institution | Institution",
"gpt4_summary": "The patient is a suspect for glaucoma based on cup to disc ratio and is on glaucoma medication, timolol. They exhibit perifoveal cystic fluid in the right eye, and retinal thinning in both, with no notable family history of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09836",
"image_path": "slo_fundus_09836.jpg",
"filename": "data_09836.npz",
"report": "The 72-year-old male patient has severe mixed-mechanism glaucoma in the left eye. His intraocular pressure (IOP) is controlled. The Avastin injection was requested and performed successfully without complications.",
"age": 72.59,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "72 y.o. male referred from PERSON for nvg os 1. mixed-mechanism glaucoma, severe stage, left eye (nvg/pds - possibly confounded by crao os/naion ou) - nvi/nva on exam DATE_TIME - iop controlled on drops but was high DATE_TIME - avastin injection requested by glaucoma - r/b/a discussed with patient, will proceed with avastin injection discussed follow up plan with dr. PERSON - he will see this patient in DATE_TIME and refer back to us if needed. rossin vitreoretinal procedure note date: PERSON pre op diagnosis: 1. neovascular glaucoma os post-op diagnosis: same provider: PERSON procedure: 1. intravitreal injection os avastin anesthesia: 1. topical 0.5% proparacaine 2. subconjunctival 2% lidocaine complications: none procedure: after the risks, benefits, alternatives and techniques were discussed with the patient, all questions were answered and informed consent was signed. proparacaine was instilled onto the ocular surface followed by 4% topical lidocaine on cotton tip then by subconjunctival 2% lidocaine. the eye was prepped in the usual fashion for this procedure. once analgesia was achieved a lid speculum was placed. calipers were used to mark 3.5 mm posterior to the limbus at DATE_TIME. a drop of povidone was placed on the surface. a 30 guage needle was used to inject PERSON intravitreally. speculum was removed and additional gatifloxicin was applied. vision was lp and the optic nerve perfused. the patient tolerated the procedure well and there were no complications. ? rd precautions reviewed.?? ? patient was discharged home in stable condition, they will follow up DATE_TIME in clinic PERSON, PERSON",
"gpt4_summary": "The 72-year-old male patient has severe mixed-mechanism glaucoma in the left eye. His intraocular pressure (IOP) is controlled. The Avastin injection was requested and performed successfully without complications.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09839",
"image_path": "slo_fundus_09839.jpg",
"filename": "data_09839.npz",
"report": "Female patient with elevated intraocular pressure (IOP) and ocular hypertension, referred by optometrist. Has family history of glaucoma. No need for IOP lowering medication currently.",
"age": 31.04,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "female presenting for evaluation of elevated iop. referred by optometrist. currently DATE_TIME pregnant. psychologist, husband is a neonatology fellow at bch 1. ocular hypertension -referred by optometrist, reportedly 'elevated iop x DATE_TIME, low DATE_TIME. -family history of glaucoma (maternal uncle) -open on gonio todau ou DATE_TIME -iop 19/20 on PERSON: true iop is lower than measured hvf DATE_TIME: normal ou oct DATE_TIME: borderline inferior od, otherwise normal -no need for iop lowering medication at this time -recommend DATE_TIME monitoring with hvf, DATE_TIME. refractive error -wears contacts and glasses alternating. -mrx given defer dilation DATE_TIME, DATE_TIME pregnant liebman pgy3 i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow. i have reviewed the resident/fellow's notes and made any necessary changes.",
"gpt4_summary": "Female patient with elevated intraocular pressure (IOP) and ocular hypertension, referred by optometrist. Has family history of glaucoma. No need for IOP lowering medication currently.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09840",
"image_path": "slo_fundus_09840.jpg",
"filename": "data_09840.npz",
"report": "The patient has severe sequential NAION with atypical features, bilateral choroidal folds, and a choroidal nevus. Anisocoria is present. No glaucoma was mentioned.",
"age": 58.3,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "katz) as a risk factor for naion. unrelated to the above, i also found anisocoria, which is probably a 'tonic' pupil given the sectoral palsy observed with slit lamp evaluation. the patient already had a thorough work up to rule out giant cell arteritis, inflammatory and infectious processes including sarcoidosis and syphilis and malignancies which reinforces the likelihood of this being consistent with naion. the acute and sequential nature of visual loss also favors this hypothesis. in this context, i would not suggest any further investigation. the decision of continuing the systemic corticosteroids will be discussed with URLllery, as he is the primary neuro-ophthalmologist on this case. i referred the patient for vision rehabilitation and emphasized the importance of ocular protection. she will continue her follow up with URLllery and neurology and i will be pleased to see her again if needed. impression: 1. severe sequential naion with atypical features 2. bilateral choroidal folds os > od - likely related to moderate hyperopia 3. choroidal nevus os - no signs suspicious for malignancy 4. anisocoria os > od - ?tonic pupil recommendations: 1. referral to vision rehabilitation 2. systemic corticosteroids per URLllery and neurology 3. follow-up neuro-ophthalmic examination with URLllery this note was prepared with the assistance of PERSON, neuro-ophthalmology fellow. i spent DATE_TIME with this patient, reviewing her history and exam and the results of multiple tests. considerable time also was given for discussion of management.) *hayreh PERSON and PERSON, incipient nonarteritic anterior ischemic optic neuropathy, ophthalmology",
"gpt4_summary": "The patient has severe sequential NAION with atypical features, bilateral choroidal folds, and a choroidal nevus. Anisocoria is present. No glaucoma was mentioned.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09841",
"image_path": "slo_fundus_09841.jpg",
"filename": "data_09841.npz",
"report": "The patient has advanced glaucoma in both eyes, with intraocular pressure goals of <= 12 mmHg. She's managing it with brimonidine and latanoprost and may need future eye surgery.",
"age": 85.72,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "previously seen at boston medical center. her son recently moved to providence. attending's plan: -goal intraocular pressure less than or equal to 12 mmhg, right eye (note thin ccts). -goal intraocular pressure less than or equal to 12 mmhg, left eye (note thin ccts). -advanced disease ou with central islands remaining os>od. -iop at goal od and at goal os on DATE_TIME on PERSON, brimonidine tid od, latanoprost qhs ou, and s/p phaco/bgi ou (open ou). -continue PERSON. -continue brimonidine tid od. -continue latanoprost qhs ou. -instructions written/typed/printed out for patient (see table/details under patient instructions) previously. -emphasized adherence to medication regimen. -encouraged tight blood glucose, blood pressure and blood cholesterol control. -preservative-free artificial tears as needed. -long discussion with patient and daughter-in-law on DATE_TIME: given great PERSON ou and numerous post-operative visits related to od, patient wishes to wait for phaco/bgi os. patient is aware that she will need surgery os at some point, and i will strongly recommend it if iop above goal os or any further progression. -mrx given by dr. PERSON on DATE_TIME. patient may need yag cap od in the future. -long discussion with patient on DATE_TIME: we proceeded with phaco/bgi os on DATE_TIME given great iop on less medication od and iop above goal os. -rtc in DATE_TIME with iop check ou, hvf 10-2 od (with coaching), and disc photos ou, sooner prn. if hvf worsens any further od, strongly consider rhopressa qhs od/os and lowering goal to 08 mmhg od/os. the information above was documented by Person as a scribe for PERSON on DATE_TIME.",
"gpt4_summary": "The patient has advanced glaucoma in both eyes, with intraocular pressure goals of <= 12 mmHg. She's managing it with brimonidine and latanoprost and may need future eye surgery.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09845",
"image_path": "slo_fundus_09845.jpg",
"filename": "data_09845.npz",
"report": "63-year-old male with proliferative diabetic retinopathy and a good visual acuity. Also has cataracts, refractive error, and an improved vision of 20/25. Referred to a glaucoma service.",
"age": 63.9,
"gender": "male",
"race": "white",
"ethnicity": "hispanic",
"language": "spanish",
"maritalstatus": "married or partnered",
"note": "63 y.o. male with PERSON patient of dr. PERSON (PERSON) previously seen in LOCATION ew in DATE_TIME but no followup until DATE_TIME then saw dr. PERSON (had prp), and then tallman eye associates (anti-vegf) proliferative diabetic retinopathy ou without macular edema pdr od with ncvh s/p 27g ppv/ el/ fax DATE_TIME (ekim/ yy) -va much improved to 20/25 \u00ff new vh os DATE_TIME - recommend more laser - rba discussed, pt requests for us to proceed treatment schedule os DATE_TIME pascal prp os DATE_TIME indirect prp os DATE_TIME indirect prp os erm od good visual acuity, observe for now cataract ou - observe \u00ff refractive error - per dr. PERSON combigan bid od and dorzolamide bid od - referral to glaucoma service\u00ff\u00ff plan: - keep head elevated - bs/bp control emphasized - indirect prp DATE_TIME os - repeat in DATE_TIME PERSON, md",
"gpt4_summary": "63-year-old male with proliferative diabetic retinopathy and a good visual acuity. Also has cataracts, refractive error, and an improved vision of 20/25. Referred to a glaucoma service.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09846",
"image_path": "slo_fundus_09846.jpg",
"filename": "data_09846.npz",
"report": "Patient to start latanoprost treatment daily for both eyes, an indication of glaucoma. Planned follow-up for refraction, eye pressure checks, and dilation at next glaucoma clinic visit.",
"age": 59.41,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "work for her. will refract her at next visit. start latanoprost daily both eyes last dilated exam: DATE_TIME last oct rnfl: DATE_TIME last visual field: DATE_TIME baseline disc photos: none return to glaucoma clinic in DATE_TIME for wrx/arx/mrx, dfe and intraocular pressure check on ltn, please check intraocular pressure with both ora and gat before dilation, thank you. i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "Patient to start latanoprost treatment daily for both eyes, an indication of glaucoma. Planned follow-up for refraction, eye pressure checks, and dilation at next glaucoma clinic visit.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09848",
"image_path": "slo_fundus_09848.jpg",
"filename": "data_09848.npz",
"report": "76-year-old female patient for follow-up of glaucoma. Currently using latanoprost after temporary switch to bimatoprost. Diagnosed with pseudoexfoliation glaucoma and narrow angles in left eye. Left eye also has a cataract, dry eye syndrome, and an epiretinal membrane. Patient declined cataract surgery. Prescribed artificial tears for dry eye syndrome. New prescription for glasses provided.",
"age": 76.97,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "married or partnered",
"note": "76 f for f/u of glaucoma. last visit here with me was in DATE_TIME. saw an ophthalmologist while in LOCATION in DATE_TIME. reports that she was given bimatoprost to use while there instead of latanoprost but she is back on latanoprost now. # pseudoexfoliation glaucoma, left eye. faint pseudoexfoliation material is noted for the first time DATE_TIME. # hx of narrow angles, left eye, s/p laser peripheral iridotomy (DATE_TIME PERSON). iridotomy is patent and angle is reasonably open. [ oct DATE_TIME: full od, sup/inf thinning os (stable) [ hvf DATE_TIME: suspicious for superonasal defect od, consistent inferior arc os (similar to before) - iop appears acceptable DATE_TIME. continue latanoprost os qhs. - discussed risk of glaucoma, accelerated cataract progression, and complications during cataract surgery. # cataract, left > right eye. borderline visually significant, particularly on glare testing in the left eye. - discussed elective cataract surgery. pt is not interested at this time and feels vision is currently adequate for functional needs. - continue to monitor. - pt would like to update glasses. discussed that vision will be limited by cataract even with new glasses. # dry eye syndrome, mild. - artificial tears 1 gtt ou qid prn. - minimize environmental factors (e.g., fans, hair dryers, smoke). # epiretinal membrane, left eye, not visually significant. # old posterior vitreous detachment, left eye. no retinal breaks seen. - monitor; return for new symptoms. # refractive error, some change from previous, would like to update glasses. - new rx given to patient. rtc DATE_TIME, sooner prn",
"gpt4_summary": "76-year-old female patient for follow-up of glaucoma. Currently using latanoprost after temporary switch to bimatoprost. Diagnosed with pseudoexfoliation glaucoma and narrow angles in left eye. Left eye also has a cataract, dry eye syndrome, and an epiretinal membrane. Patient declined cataract surgery. Prescribed artificial tears for dry eye syndrome. New prescription for glasses provided.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09851",
"image_path": "slo_fundus_09851.jpg",
"filename": "data_09851.npz",
"report": "The patient has an early lamellar hole in the left eye, noticed blurry vision when reading TV captions. There's no indication of glaucoma. The patient stopped taking Ocuvites as advised. Observation is recommended. A retinal hemorrhage was resolved in the right eye.",
"age": 79.86,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "-oct DATE_TIME: normal foveal contour -oct DATE_TIME: os early lamellar hole, no cysts, stable. -oct DATE_TIME: os early lamellar hole, no cystic changes--> very mild clinically, observe >> recommended by outside ophthalmologist to take ocuvites >> discussed not indicated DATE_TIME and has stopped taking them -patient noticing more blurry vision os when trying to reading captions on tv, fine with glasses on but didn't have to use them before DATE_TIME DATE_TIME: od tr erm nasally. os tr erm, tr irreg contour. no cme \u00ff 4. des ou >> has not been using at \u00ff 5. retinal hemorrhage od superior periphery on exam DATE_TIME, resolved -maintain htn control",
"gpt4_summary": "The patient has an early lamellar hole in the left eye, noticed blurry vision when reading TV captions. There's no indication of glaucoma. The patient stopped taking Ocuvites as advised. Observation is recommended. A retinal hemorrhage was resolved in the right eye.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09852",
"image_path": "slo_fundus_09852.jpg",
"filename": "data_09852.npz",
"report": "63-year-old female with myopia, astigmatism, presbyopia, nuclear cataract, and MG/D. She's a suspect for glaucoma due to asymmetry. No family history of glaucoma. Patient experiences halos & difficulty driving.",
"age": 63.41,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "63 yro female 1. myopia astigmatism ou with presbyopia - small change in ou; ok to continue current glasses - new rx=mrx given to pt 2. glaucoma suspect secondary to asymmetry c/d od>os - negative f/h - iop DATE_TIME: 12/12 - c/d ratio: od: 0.60; os: 0.40 - cct: DATE_TIME nfl in DATE_TIME, DATE_TIME, DATE_TIME, DATE_TIME and DATE_TIME DATE_TIME: PERSON oct gcc: normal ou - hvf on DATE_TIME, DATE_TIME and DATE_TIME: full ou - pt edu, will monitor DATE_TIME. nuclear cataract ou - pt c/o halos, difficulty driving at DATE_TIME - discuss cataract surgery vs observe, will observe - monitor DATE_TIME. mgd/des ou - continue at's bid and gel qhs ou - warm compresses qd 5. h/o hemorrhagic pvd w/ operculated holes os, s/p laser DATE_TIME; trace erm os - stable - continue to f/u with dr. PERSON as instructed *deferred dilation DATE_TIME because she was dilated by dr. PERSON DATE_TIME; pt has no flashing light; no changes on floaters. pt understands.",
"gpt4_summary": "63-year-old female with myopia, astigmatism, presbyopia, nuclear cataract, and MG/D. She's a suspect for glaucoma due to asymmetry. No family history of glaucoma. Patient experiences halos & difficulty driving.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09854",
"image_path": "slo_fundus_09854.jpg",
"filename": "data_09854.npz",
"report": "The patient has a history of head trauma, asthma treated with steroids, and glaucoma. They couldn't tolerate Lumigan and Travatan. Options of adding drops or Selective Laser Trabeculoplasty were discussed.",
"age": 72.15,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "# NRP, os>od prev seen PERSON could not tolerate lumigan, travatan and LOCATION h/o head trauma and PERSON; + steroids for asthma last use DATE_TIME ; +gm with glaucoma no prior surgery/lasers ttarget: / , tmax: 21 / 22 per pt cct: 515, 515, 515 / 484, 484, 484 gonioscopy: ptm/ss ou rnfl oct nml od, diffuse loss of rnfl and gcc os vf nml od, nasal defect os (only prior test from DATE_TIME) plan: based on level of damage , tmax and cct, target os should be at least 15 , if not lower od target 18 discussed options of adding drops vs slt -- he would like to proceed with slt os will schedule if delayed should see me in 3 mths for repeat vf and dilation ou cont travatan os for now corkscrew vessels ou, h/o head trauma, however low suspicion for cc fistula as bilateral, no blood in sc on gonio and iop symmetric discussed with patient, will monitor diagnosis of glaucoma/glaucoma suspect discussed with patient - review of natural history and management options discussed. importance of lifelong follow up and adherence to treatments discussed in order to lower risk of permanent vision loss/blindness from glaucoma. all questions answered. i spent DATE_TIME with the patient, more than half of which was spent on counseling and coordination of care for this patient's glaucoma",
"gpt4_summary": "The patient has a history of head trauma, asthma treated with steroids, and glaucoma. They couldn't tolerate Lumigan and Travatan. Options of adding drops or Selective Laser Trabeculoplasty were discussed.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09858",
"image_path": "slo_fundus_09858.jpg",
"filename": "data_09858.npz",
"report": "Patient transferred care to Dr. Sol. Goals include intraocular pressure <=18 mmhg in both eyes; current measurements exceed these goals. Patient previously off glaucoma meds, advised to restart brimonidine. Anxiety noted.",
"age": 50.84,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "chwalisz/dr. cestari for neuro-ophthalmic care. 6. social/systemic issues: prior patient of dr. PERSON's and dr. PERSON's (she chose to transfer care to dr. sol ); her name is gaelic. attending's plan: -goal intraocular pressure less than or equal to 18 mmhg, right eye. -goal intraocular pressure less than or equal to 18 mmhg, left eye. -iop above goal od and above goal os on DATE_TIME off glaucoma medications. -restart brimonidine bid ou. -emphasized adherence to medication regimen. -preservative-free artificial tears as needed. -follow-up with dr. PERSON/dr. PERSON for neuro-ophthalmic care => patient is very anxious about her neurologic symptoms, so i messaged dr. PERSON on DATE_TIME to see if his appointment could be moved up. -follow-up with dr. PERSON for cornea care. -follow-up with dr. PERSON for refractive care/optometry needs. -rtc in DATE_TIME for iop check, pachymetry, dilation, and disc photos ou, sooner prn. consider slt if adherence to medication is an issue.",
"gpt4_summary": "Patient transferred care to Dr. Sol. Goals include intraocular pressure <=18 mmhg in both eyes; current measurements exceed these goals. Patient previously off glaucoma meds, advised to restart brimonidine. Anxiety noted.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09863",
"image_path": "slo_fundus_09863.jpg",
"filename": "data_09863.npz",
"report": "The 58 y.o patient complains of poor distance vision due to cataracts. Has history of eye injury, ocular hypertension with intraocular pressure (IOP) of 26. No mention of glaucoma.",
"age": 58.67,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "58 y.o. referred by dr. PERSON md (berkshire medical center) hx of PERSON ou, in LOCATION DATE_TIME - no ectasia congenital cataracts ou - central anterior subcapsular cataracts - os with traumatic cataract as well - complains of poor distance vision, however, he is only using contact in the right eye. would correct both eyes for distance and reevaluate in DATE_TIME hx of injury to os at DATE_TIME, hit with a chunk of ice - had patch, possibly had hyphema, developed cataract - has 2-3 quadrants of angle recession nasally - iop at 26 ou ocular hypertension ou - iop 26 ou - gonio od open os angle recession nasally - cct DATE_TIME od wnl os borderline thin sup - hvf DATE_TIME essentially full ou > observe reevaluate in DATE_TIME mrx, bat dilate",
"gpt4_summary": "The 58 y.o patient complains of poor distance vision due to cataracts. Has history of eye injury, ocular hypertension with intraocular pressure (IOP) of 26. No mention of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09868",
"image_path": "slo_fundus_09868.jpg",
"filename": "data_09868.npz",
"report": "The clinical note is scribed by a glaucoma fellow for Dr. PERSON. The fellow attests their presence during the encounter recording and agrees that the provided information is accurate.",
"age": 78.97,
"gender": "male",
"race": "white",
"ethnicity": "hispanic",
"language": "unknown",
"maritalstatus": "married or partnered",
"note": "md glaucoma fellow PERSON scribing for dr. PERSON i attest that i was present while this encounter was recorded and agree that the information entered by my scribe and updated by me is complete and accurate. PERSON, md",
"gpt4_summary": "The clinical note is scribed by a glaucoma fellow for Dr. PERSON. The fellow attests their presence during the encounter recording and agrees that the provided information is accurate.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09871",
"image_path": "slo_fundus_09871.jpg",
"filename": "data_09871.npz",
"report": "82-year-old patient with pseudophakia and age-related macular degeneration. Large c/d ratio and central defect progression suggest glaucoma. Currently on latanoprost and brimonidine eye drops, but a referral for glaucoma surgery is recommended.",
"age": 82.78,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "divorced",
"note": "82 yo female from krimea, here for follow-up, iop check, hvf, DATE_TIME. pseudophakia os doing well, happy with vision says she sees better when she tilts her glasses but does not want to be refracted DATE_TIME. PERSON (done in LOCATION) visual axis clear 3. age-related macular degeneration dry changes DATE_TIME: no fluid monitor 4. large c/d ratio osPERSON, but has progression of central defect os tmax 20/19 pachy 523/517, true iop higher than measured hvf DATE_TIME: dense inferior paracentral scotoma and possibly early superior arcuate defect os od with mild inferior nasal changes hvf DATE_TIME: unreliable od, superior defect os not very reliable, dense paracentral scotoma, superior and inferior defects hvf DATE_TIME: od full, os with worsening central defect hvf DATE_TIME: od full, os with worsening inferior and early sup arcuate defect oct rnfl DATE_TIME: od inf thinning, os sup and PERSON thinning DATE_TIME: stable (volumes a little worse) oct rnfl DATE_TIME: stable taking latanoprost, LOCATION and brimonidine ou iop 16/17 DATE_TIME rec: - cont same drops, increase brimonidine to tid - refer to glaucoma for consideration of surgery os 5. thyroid disease prominent globes, lid retraction no diplopia hertel DATE_TIME base 97, 23mm ou",
"gpt4_summary": "82-year-old patient with pseudophakia and age-related macular degeneration. Large c/d ratio and central defect progression suggest glaucoma. Currently on latanoprost and brimonidine eye drops, but a referral for glaucoma surgery is recommended.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09872",
"image_path": "slo_fundus_09872.jpg",
"filename": "data_09872.npz",
"report": "The patient is a glaucoma suspect under Boston Eyecare Consultants' care. Initial optic nerve findings and visual fields were healthy and normal respectively. No glaucoma procedures were done. Both eyes have epiretinal membrane. Plan is to monitor intraocular pressure.",
"age": 62.93,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "first seen by PERSON PERSON on DATE_TIME, followed at boston eyecare consultants diagnosis: glaucoma suspect, followed in falmouth, borderline vf left eye target iop: DATE_TIME, tmax: 23 (per patient) / 26.2 (DATE_TIME) central corneal thickness: 661 / 660 gonioscopy: open refractive error: od LOCATION. -2.50. 100 / os -3.25. -1.75. 085 optic nerve findings on initial visit right eye: healthy optic nerve findings on initial visit left eye: healthy visual fields on initial visit right eye: normal visual fields on initial visit left eye: normal medication history and intolerances at first visit: none glaucoma procedures right eye: glaucoma procedures left eye: other eye procedures right eye: other eye procedures left eye: other eye problems right eye: epiretinal membrane other eye problems left eye: epiretinal membrane family history: steroids: no trauma: no asthma: no other medical history and problems: colon ca DATE_TIME initial plan: slightly large cdr, has been monitored for DATE_TIME. PERSON. intraocular pressure left eye often higher than right eye plan: stable, check DATE_TIME, early cataracts. left eye tends to run higher, low threshold to treat return to clinic DATE_TIME, testing and dilation i, PERSON, am acting as scribe for PERSONmd, PERSON for patient PERSON on DATE_TIME. - Person i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "The patient is a glaucoma suspect under Boston Eyecare Consultants' care. Initial optic nerve findings and visual fields were healthy and normal respectively. No glaucoma procedures were done. Both eyes have epiretinal membrane. Plan is to monitor intraocular pressure.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09873",
"image_path": "slo_fundus_09873.jpg",
"filename": "data_09873.npz",
"report": "The patient has idiopathic intracranial hypertension but does not exhibit glaucoma. Recommendations include continuation of acetazolamide, weight loss, and a follow-up neuro-ophthalmology exam.",
"age": 24.27,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "my read does not show a cause of intracranial hypertension. they are not on any typical inciting medications but we have seen patients that in the setting of hormonal changes related to gender conversion (in this case using testosterone pellets recently) have iih. we will await a formal read on mri/mrv and also recommend obtaining an lp to check csf constituents and get an opening pressure. we prescibed diamox for the patient to start. we will have her return to neuro-oph clinic in DATE_TIME. impression: 1. idiopathic intracranial hypertension recommendations: 1. continue acetazolamide 500mg 2x/day 2. continue weight loss efforts with end goal of 6-10% of current body weight lost through low salt diet and increased physical activity 3. follow up neuro-ophthalmology exam DATE_TIME. lumbar puncture with opening pressure and standard labs (glucose, protein, cell count/differential, gram stain and culture) - please obtain at Institution before patient is discharged. please get opening pressure in lateral decubitus position. 2. start 500mg 2x/day acetazolamide - rx sent 3. weight loss with end goal of 6-10% of current body weight lost through low salt diet and increased physical activity 4. follow-up neuro-ophthalmic examination in DATE_TIME this note was prepared with the assistance of PERSON, neuro-ophthalmology fellow.",
"gpt4_summary": "The patient has idiopathic intracranial hypertension but does not exhibit glaucoma. Recommendations include continuation of acetazolamide, weight loss, and a follow-up neuro-ophthalmology exam.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09876",
"image_path": "slo_fundus_09876.jpg",
"filename": "data_09876.npz",
"report": "The clinical note did not mention the presence of glaucoma. The patient's case involves a moderate risk of visual or neurological problems. Management and treatment options are being discussed with the attending doctors.",
"age": 34.1,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "married or partnered",
"note": "that pose a threat to vision, neurological function or systemic health. my assessment of this case also included review of the following data: 1) results of tests and outside documents; review of unique test results (including those described under 'ancillary studies' above); ordering unique tests; assessment requiring independent historian); mri brain and orbits and mrv 2) independent interpretation of tests performed by dr. sokol/dr. PERSON ; and 3) discussion or communication of management with dr. . with respect to management, this patient has a - potentially moderate risk of visual or neurological morbidity related to the above diagnoses and considerations of management (including treatment limited by social determinants or health). i spent a total of greater than (DATE_TIME preparing and caring for this patient (face-to-face and non face-to-face); formulating (including review of the presentation with the resident or fellow or review of medical tests) and finalizing the note.]",
"gpt4_summary": "The clinical note did not mention the presence of glaucoma. The patient's case involves a moderate risk of visual or neurological problems. Management and treatment options are being discussed with the attending doctors.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09877",
"image_path": "slo_fundus_09877.jpg",
"filename": "data_09877.npz",
"report": "Patient has right eye soreness. No diabetic retinopathy found. Cataract in both eyes, minimal, not visually significant. Glaucoma suspect with increased cup/disc ratio in right eye. Further evaluation needed.",
"age": 55.92,
"gender": "female",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "legally separated",
"note": "DATE_TIME, DATE_TIME PERSON, md, mph 440 LOCATION DATE_TIME PERSON patient: PERSON mr number: NUMBER date of birth: DATE_TIME date of visit: DATE_TIME i saw our mutual patient, PERSON, for a follow-up eye examination. please find below a summary of the examination, assessment, and plan. thank you for allowing me to participate in this patient's care. 55 f hx htn, dm, LOCATION. works at spaulding last a1c 9.60 on DATE_TIME has had DATE_TIME of eye soreness and irritation in the lateral canthus of the right eye # capped PERSON vs early chalazion, r upper eyelid - discussed warm compresses and lid massage # no evidence of diabetic retinopathy. - importance of blood glucose and blood pressure control discussed with patient. - annual dilated eye exams, sooner prn visual changes. # cataract, both eyes. minimal and not visually significant in both eyes. - continue to monitor. # glaucoma suspect with increased cup/disc ratio, right > left eye [ fhx: unknown [ cct: 524,515 [ DATE_TIME: full ou [ hvf DATE_TIME: full ou - no intervention required at this time. continue to monitor. # conjunctival melanosis, both eyes. appears benign. - photos taken previously # dry eye syndrome, mild. - artificial tears 1 gtt ou qid prn. - minimize environmental factors (e.g., fans, hair dryers, smoke). # refractive error, minimal change from previous, would like to update glasses. - new rx given to patient. rtc 1 year with hvf/oct/dilation, sooner prn if you have questions, please do not hesitate to contact me sincerely, PERSON: no recipients",
"gpt4_summary": "Patient has right eye soreness. No diabetic retinopathy found. Cataract in both eyes, minimal, not visually significant. Glaucoma suspect with increased cup/disc ratio in right eye. Further evaluation needed.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09882",
"image_path": "slo_fundus_09882.jpg",
"filename": "data_09882.npz",
"report": "Patient has right eye pain, possible occipital neuralgia. Small exophoria (convergence insufficiency) present. Plan: trial occipital nerve block. No mention of glaucoma.",
"age": 70.96,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "and otherwise good afferent visual function, and normal posterior poles. there is also a small exophoria at near (convergence insufficiency pattern). to external palpation, there is: mild tenderness over the right eye and right external temporalis tendon, and significant tenderness over the right greater & lesser occipital nerve my overall impression is that the right eye pain is likely referred from the neck vs cervicogenic occipital neuralgia. however, should a connection to her systemic inflammatory disease become established, i would advocate for initiating systemic immune suppression. my plan is: - trial of occipital nerve block - defer trial of neuropathic pain medicine for now - defer immunomodulatory therapy for now we discussed this diagnostic impression and plan in detail. we have not scheduled further follow-up but i am happy to see the patient again if the need arises. thank you for allowing me to participate in the care of your patient. ???? ??please do not hesitate to call with questions. ? sincerely, ? PERSON, LOCATION neuro-ophthalmology, headache unit, and inflammatory neuro-ophthalmology/skull base disorders clinic. division of comprehensive neurology, Institution neuro-ophthalmology, Institution ? note: greater than half of this DATE_TIME visit was spent counseling the patient on the medical condition or coordinating care. this time excludes any listed procedures.",
"gpt4_summary": "Patient has right eye pain, possible occipital neuralgia. Small exophoria (convergence insufficiency) present. Plan: trial occipital nerve block. No mention of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09883",
"image_path": "slo_fundus_09883.jpg",
"filename": "data_09883.npz",
"report": "Patient has choroidal nevus in right eye, mild cataract in both eyes, and has had bilateral upper lid blepharoplasty. No mention of glaucoma.",
"age": 69.96,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "currently # choroidal nevus, right eye - monitor # cataract, both eyes - mild, not visually significant, monitor # s/p bilateral upper lid blepharoplasty (dr. PERSON at tufts) - monitor PERSON scribing for dr. PERSON i attest that i was present while this encounter was recorded and agree that the information entered by my scribe and updated by me is complete and accurate. PERSON, md",
"gpt4_summary": "Patient has choroidal nevus in right eye, mild cataract in both eyes, and has had bilateral upper lid blepharoplasty. No mention of glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09884",
"image_path": "slo_fundus_09884.jpg",
"filename": "data_09884.npz",
"report": "The note recommends using artificial tears or ointments 4-6 times a day for eye irritation from blepharitis. A warm pack aids relief. Lid scrubs with baby shampoo in the shower are advised. No mention of glaucoma.",
"age": 63.21,
"gender": "female",
"race": "black",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "single",
"note": "artificial tears/ointments artificial tears, which you can get without a prescription, will often help relieve eye irritation associated with blepharitis. use the drops 4 to 6 times a day unless your doctor instructs otherwise. you can also use artificial tear ointments at bedtime. drops: any brand is okay. examples that i like include: refresh or systane ointments: any brand is okay. examples that i like include refresh pm, PERSON, or genteal warm compresses: twice a day for a month, then once a day if you have a warm pack: 1. wash your hands. 2. heat the warm pack until quite warm but not burning. 3. wrap the warm pack in a paper towel and set on the bones around your eyes with your lids closed. keep the pack on for DATE_TIME. you will probably not need to reheat it. 4. wash your lids gently with warm water. if you do not have a warm pack: 1. wash your hands. 2. heat up a clean washcloth using very warm tap water. 3. wring out the washcloth and hold it over your closed lids until it cools. 4. repeat until you have had a warm washcloth over your lids for DATE_TIME. 5. wash your lids gently with warm water. lid scrubs 1. in the shower, use johnson+johnson baby shampoo to wash eyelids and eyelashes 2. avoid getting shampoo in your eye",
"gpt4_summary": "The note recommends using artificial tears or ointments 4-6 times a day for eye irritation from blepharitis. A warm pack aids relief. Lid scrubs with baby shampoo in the shower are advised. No mention of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09886",
"image_path": "slo_fundus_09886.jpg",
"filename": "data_09886.npz",
"report": "Glaucoma suspect due to cup/disk ratio. Floaters and flashes have resolved. Excellent intraocular pressure. Retinal detachment discussed. Possible ocular migraines. Myopic astigmatism and mild cataracts present but not significant.",
"age": 58.82,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "58 y.o. woman presents for follow-up # vitreous PERSON - symptoms in DATE_TIME which she described as new 'shadow, like when drops fall down near your eyes when it's raining' followed by flashes of light in the temporal field of vision (like a mirror moving in the temporal field of vision). also noted pressure like sensation around the eye. -in ew exam, weiss ring was not seen and these were thought to be possibly 2/2 ocular migraines. - no weiss ring present on exam DATE_TIME. - no evidence of holes, tears, or detachment. PERSON's sign negative on last dfe - floaters and flashes since resolved >retinal detachment warning signs discussed with patient. # glaucoma suspect by cup/disk ratio: - no history of trauma - no family history - normal iop DATE_TIME DATE_TIME - cct 566/581 (DATE_TIME) - od>os -oct rnfl DATE_TIME: sup thinning od, focal borderline sup/temp thinning os -hvf DATE_TIME: reliable and full ou >continue to monitor off drops given excellent iop and thick corneas # myopic astigmatism: - updated mrx given previously # mild-age related cataracts: - not visually significant, ctm #ocular migraine, od? - visual symptoms attributed to ocular migraine in past. possibly consistent with vitreous syneresis as above but unusual to have periocular pressure pain. - no repeat episodes after. # fevers of unknown etiology: follows with rheumatology. fu DATE_TIME, oct PERSON, PERSON i saw and evaluated this patient and discussed the case as appropriate with the resident. i have reviewed the resident's notes and made any necessary changes. PERSON",
"gpt4_summary": "Glaucoma suspect due to cup/disk ratio. Floaters and flashes have resolved. Excellent intraocular pressure. Retinal detachment discussed. Possible ocular migraines. Myopic astigmatism and mild cataracts present but not significant.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09890",
"image_path": "slo_fundus_09890.jpg",
"filename": "data_09890.npz",
"report": "The 83-year-old male patient is a high-risk glaucoma suspect due to c/d asymmetry. His intraocular pressure (IOP) is not being controlled and he has shown possible progression in his visual field. He also has pseudophakia in both eyes, a history of hemorrhagic PVD in the right eye, and age-related macular degeneration.",
"age": 84.13,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "unknown",
"maritalstatus": "divorced",
"note": "83 y.o. m \u00ff son PERSON referred by PERSON for glaucoma monitoring np to me DATE_TIME \u00ff # glaucoma suspect, high risk, due to c/d asymmetry od>os, possible dh od DATE_TIME tmax 23/21 (28 os pod#1). cct DATE_TIME. no known fhx (parents lived in small village, minimal health care) gonio DATE_TIME: cbb 360 od and os oct : overall full, slightborderline sup thinning od>os hvf : DATE_TIME, grossly full with paracentral depressions od; DATE_TIME poor reliability but possible progression of inferior depressions od \u00ff goal iop high teens ou - again, not at goal, has not taken ltn for DATE_TIME. we discussed the importance of lowering the iop to goal, given that hvf appears worse DATE_TIME. \u00ff # pseudophakia ou (dr PERSON) s/p phaco/pciol ou (DATE_TIME od and DATE_TIME os), trace ifis - happy with vision, using otcs \u00ff # hx hst od s/p laser PERSON (PERSON) DATE_TIME s/p hemorrhagic pvd od DATE_TIME - retina attached - rd precautions reviewed \u00ff # amd ou - intermediate dry od with rpd - wet os, type ii cnvm - getting injections os with PERSON, last DATE_TIME \u00ff \u00ff plan resume PERSON emphasized and progression on hvf reviewed with patient. new rx sent in. DATE_TIME dilate oct rnfl gcc \u00ff",
"gpt4_summary": "The 83-year-old male patient is a high-risk glaucoma suspect due to c/d asymmetry. His intraocular pressure (IOP) is not being controlled and he has shown possible progression in his visual field. He also has pseudophakia in both eyes, a history of hemorrhagic PVD in the right eye, and age-related macular degeneration.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09892",
"image_path": "slo_fundus_09892.jpg",
"filename": "data_09892.npz",
"report": "The male patient works at an orchestra, suspected of glaucoma with risks including myopia, c/d asymmetry, and IOP at 16/16. Experienced eye strain playing video games. Referred for glaucoma evaluation.",
"age": 49.2,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "PERSON is a DATE_TIME. male pt works at LOCATION symphony orchestra glaucoma suspect risks include: myopia, c/d asym, inferior gcl lost and superior arcuate change on hvf iop 16/16. tcorr -3 ou oct rnfl thin ou. PERSON but myopic hvf 24-2: watch supero-temporal od denies steroid use normal bp, thyroid and normal testing per patient prior treatment for hepc denies transfusion and prior trauma refer to glaucoma for evaluation myopia with presbyopia ou pt notes that he has to take glasses to see up close, phone, computer his current glasses hurt his eyes optional rx dispensed pt reports he experiences eye strain when playing nintendo switch (video game) as a handheld whether or not while wearing glasses. when playing on the tv, pt does not experience eye strain. warned of PERSON dry eye ou gave pt dry eye handout recommend at's prn avoid heat/rubbing avoid visine and other medications that 'get the red out' pt admits to using visine prn ou DATE_TIME -- advised pt to avoid using this f/u with glaucoma, next available.",
"gpt4_summary": "The male patient works at an orchestra, suspected of glaucoma with risks including myopia, c/d asymmetry, and IOP at 16/16. Experienced eye strain playing video games. Referred for glaucoma evaluation.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09895",
"image_path": "slo_fundus_09895.jpg",
"filename": "data_09895.npz",
"report": "The clinical note describes an 84-year-old white, non-Hispanic female who has been diagnosed with glaucoma.",
"age": 84.57,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "a 84 y.o. white, non-hispanic female was evaluated and diagnosed with glaucoma. for more detailed steps on enrollment please click the 'learn more' link underneath the 'enroll now' button on URL. important information about your account: ? if you already have a account, please sign in with your username and password. ? you must log into your account within DATE_TIME or activation code will expire. ? trouble logging in? use support link found on the top right side of the login page. ? need help? support team makes every effort to respond to phone or email messages within DATE_TIME. to reach the support team, email EMAIL_ADDRESSPHONE_NUMBER. calls or messages are answered DATE_TIME, DATE_TIME, est - and will make every effort to contact you within DATE_TIME.",
"gpt4_summary": "The clinical note describes an 84-year-old white, non-Hispanic female who has been diagnosed with glaucoma.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09898",
"image_path": "slo_fundus_09898.jpg",
"filename": "data_09898.npz",
"report": "The female patient has diabetes mellitus type 2, no retinopathy, incipient cataracts in both eyes, optic disc cupping in both eyes with IOP 15/16, CCT 492/490, and borderline changes in OCT RNFL. No glaucoma or family history. Also has fatigable ptosis.",
"age": 60.76,
"gender": "female",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "DATE_TIME. female \u00ff # diabetes mellitus type 2 -no retinopathy >importance of blood glucose, bp, and lipid control emphasized with patient \u00ff \u00ff# incipient cataract ou -not visually significant >observe \u00ff \u00ff # optic disc cupping ou - iop 15/16 - cct 492/490 - no family hx - oct rnfl DATE_TIME: borderline changes ou, stable - hvf DATE_TIME: full ou >monitor # ptosis rul> lul - feels eyes get droopy at DATE_TIME fatigable ptosis > not very bothersome to patient so she opted to observe rtc 1 year: oct rnfl + gca",
"gpt4_summary": "The female patient has diabetes mellitus type 2, no retinopathy, incipient cataracts in both eyes, optic disc cupping in both eyes with IOP 15/16, CCT 492/490, and borderline changes in OCT RNFL. No glaucoma or family history. Also has fatigable ptosis.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09901",
"image_path": "slo_fundus_09901.jpg",
"filename": "data_09901.npz",
"report": "Patient has primary open angle glaucoma in both eyes, increased intraocular pressure in right eye, mild visual field progression, stable optic nerve fiber layer and cataract in left eye.",
"age": 80.31,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "imp: poag ou, on dorzolamide ou bid; iop elevation to 27 od DATE_TIME; angles open; mild hvf progression ou, stable oct of rnfl ou cataract os PERSON error plan: cpm add xalatan ou qhs (has asthma--no beta blocker; will use LOCATION rather than PERSON=m glasses consult with glaucoma service",
"gpt4_summary": "Patient has primary open angle glaucoma in both eyes, increased intraocular pressure in right eye, mild visual field progression, stable optic nerve fiber layer and cataract in left eye.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09902",
"image_path": "slo_fundus_09902.jpg",
"filename": "data_09902.npz",
"report": "The patient had an intraocular pressure check and various eye examinations. No explicit mention of glaucoma was made in the note.",
"age": 70.28,
"gender": "female",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "care. -rtc in DATE_TIME with iop check ou, arx ou, bat os, optical biometry ou, dilation ou, and disc photos ou, sooner prn. i personally spent DATE_TIME preparing for, caring for the patient (face-to-face and non face-to-face), and finalizing the visit for this patient. the information above was documented by PERSON as a scribe for PERSON on DATE_TIME. i saw and evaluated this patient and discussed the case as appropriate with the resident/fellow (PERSON md). i have reviewed the resident/fellow's notes and made any necessary changes.",
"gpt4_summary": "The patient had an intraocular pressure check and various eye examinations. No explicit mention of glaucoma was made in the note.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09905",
"image_path": "slo_fundus_09905.jpg",
"filename": "data_09905.npz",
"report": "82 y.o female patient with severe primary open-angle glaucoma (POAG) in the right eye, mild in the left. High intraocular pressure (IOP) uncontrolled in the right eye despite medication. No family history of glaucoma. Discussed diagnosis, management options, and surgery recommendation with patient and children. Also receiving treatment for wet amd.",
"age": 82.58,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "widowed",
"note": "82 y.o. f referred by ew for elevated iop od accompanied by her adult children, PERSON (daughter) and scott - leigh has meniere's and is on diamox # poag ou, severe od, mild os, with uncontrolled iop od on mmt - tmax in recent chart history is 54/28 on DATE_TIME 25/12 on mmt including methazolamide, tolerating PERSON well (more so than diamox) - no fh glaucoma - gonio open with no pas - cct pending - refraction pending diagnosis of glaucoma/glaucoma suspect discussed with patient - review of natural history and management options discussed. importance of lifelong follow up and adherence to treatments discussed in order to lower risk of permanent vision loss/blindness from glaucoma. all questions answered. d/w patient, would benefit from sugical iop lowering, would recommend phaco-PERSON/- anti-vegf at time of surgery r/b/a to surgery including but not limited to infection, bleeding, swelling, inflammation, retinal tear/rd, need for meds, need for further procedure, risk of worsening glaucoma despite surgery, hypotony, loss of vision, loss of eye, all d/w patient and all questions answered. written consent obtained. # wet amd ou receiving injections ou (dr. PERSON, notes in epic) last injection od DATE_TIME, od DATE_TIME plan continue mmt: travatan ou qpm PERSON ou bid pilocarpine PERSON 50mg tid po rtc DATE_TIME for arx mrx lenstar and iop retina consult placed - daughter would like to establish care with retina service here for now while glaucoma is being addressed.",
"gpt4_summary": "82 y.o female patient with severe primary open-angle glaucoma (POAG) in the right eye, mild in the left. High intraocular pressure (IOP) uncontrolled in the right eye despite medication. No family history of glaucoma. Discussed diagnosis, management options, and surgery recommendation with patient and children. Also receiving treatment for wet amd.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09906",
"image_path": "slo_fundus_09906.jpg",
"filename": "data_09906.npz",
"report": "Patient is a 45-year-old black, non-hispanic male. He has no diagnosis of glaucoma. Some online enrollment steps are shared.",
"age": 45.41,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "a 45 y.o. black, non-hispanic male with no diagnosis of glaucoma. account using following steps: 1. visit URL. 2. click 'enroll now' and create your user account. for more detailed steps on enrollment please click the 'learn more' link underneath the 'enroll now' button on URL.",
"gpt4_summary": "Patient is a 45-year-old black, non-hispanic male. He has no diagnosis of glaucoma. Some online enrollment steps are shared.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09912",
"image_path": "slo_fundus_09912.jpg",
"filename": "data_09912.npz",
"report": "Patient has severe glaucoma in right eye. A DMEK procedure is advised with potential limited vision improvement. Additional suggestion to flush out residual matter to avoid damage.",
"age": 83.64,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "i think it's fine to go ahead with dmek od, but i warned her that vision may not improve significantly since it may be more limited by her severe glaucoma od. while you're in there, i think it would be a good idea to flush out the residual PERSON using some viscoelastic +/- forceps to grab since the pellet can worsen corneal endothelial health. thank you!",
"gpt4_summary": "Patient has severe glaucoma in right eye. A DMEK procedure is advised with potential limited vision improvement. Additional suggestion to flush out residual matter to avoid damage.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09913",
"image_path": "slo_fundus_09913.jpg",
"filename": "data_09913.npz",
"report": "The 55-year-old female patient is suspected of having primary open-angle glaucoma. Her mother had advanced stage normal-tension glaucoma. OCT showed borderline inferior thinning in right eye. IOP is controlled. She also has moderate myopia, a history of blepharitis/dry eye syndrome, and plugs in place.",
"age": 55.87,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "55 y.o. female h/o cervicomedullary junction meningioma (found incidentally) 1. poag suspect with strong fh glaucoma (mom with adv stage ntg). tmax 16 ou cct 530,543 hvf full ou dp stable ou oct wnl borderline inf thinning od, wnl os, stable rnfl average thickness ou c/w prior, ganglion cell analysis wnl ou iop controlled observe 2. moderate myopia mrx given doing well with current pals 3. h/o blepharitis/des ll plugs in place, relieved sx of eye pain and burning DATE_TIME, after discussion with patient she wants to leave plugs place for now at prn f/u 1 yr for mrx, PERSON, LOCATION, oct and dp",
"gpt4_summary": "The 55-year-old female patient is suspected of having primary open-angle glaucoma. Her mother had advanced stage normal-tension glaucoma. OCT showed borderline inferior thinning in right eye. IOP is controlled. She also has moderate myopia, a history of blepharitis/dry eye syndrome, and plugs in place.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09915",
"image_path": "slo_fundus_09915.jpg",
"filename": "data_09915.npz",
"report": "Patient has multiple conditions including glaucoma. Medications include potassium chloride, prochlorperazine, propranolol, ranitidine, vitamin B2, sertraline, simvastatin, timolol (for eyes) and PERSON.",
"age": 76.7,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "frequency: bid; directions: not available; details: not available; date: DATE_TIME DATE_TIME needs PERSON. metal med transfer process. potassium chloride (klor-con) 10 meq cr tablet take 3 tablets (30 meq total) by mouth DATE_TIME. potassium chloride (klor-con) 10 meq cr tablet take three tablets by mouth once DATE_TIME prochlorperazine (compazine) 10 mg tablet take one tablet by mouth DATE_TIME as needed for nausea propranolol (inderal la) 80 mg 24 hr capsule take 1 capsule (80 mg total) by mouth DATE_TIME. ranitidine (zantac) 150 mg tablet take 1 tablet (150 mg total) by mouth 2 (two) times a day. PERSON, vitamin b2, (,vitamin b-2,) 25 mg tab take 1 tablet by mouth DATE_TIME. hrishikesh sawant DATE_TIME metal med transfer process sertraline (LOCATION) 25 mg tablet take one tablet by mouth DATE_TIME simvastatin (zocor) 20 mg tablet take one tablet by mouth at bedtime timolol (timoptic-xe) 0.5 % ophthalmic gel-forming place 1 drop into each eye every morning. PERSON (ultram) 50 mg tablet take 2 tablets (100 mg total) by mouth 3 (three) times a day. URL. may request partial fill condition list as of DATE_TIME primary malignant neoplasm of endometrium multiple sclerosis hypertensive disorder hyperlipidemia osteoarthritis diverticular disease osteopenia migraine glaucoma routine general medical examination at a health care facility anxiety heart murmur chronic pain herpes zoster acute upper respiratory infection seborrheic keratosis eczema overweight medicare annual wellness visit, subsequent urinary frequency cerebral infarction results summary immunizations administered on date of encounter - DATE_TIME none",
"gpt4_summary": "Patient has multiple conditions including glaucoma. Medications include potassium chloride, prochlorperazine, propranolol, ranitidine, vitamin B2, sertraline, simvastatin, timolol (for eyes) and PERSON.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09919",
"image_path": "slo_fundus_09919.jpg",
"filename": "data_09919.npz",
"report": "The patient's intraocular pressure is at goal in both eyes and they are not on glaucoma medications. Phaco/istent treatments are proposed. Blood glucose, BP and cholesterol control is crucial. Retinal detachment measures were discussed.",
"age": 71.12,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "intraocular pressure less than or equal to 21 mmhg, right eye (arbitrarily set). -goal intraocular pressure less than or equal to 17 mmhg, left eye (arbitrarily set). -iop at goal od and at goal os on DATE_TIME off glaucoma medications. -continue close monitoring off glaucoma medications. -encouraged tight blood glucose, blood pressure and blood cholesterol control. -retinal detachment precautions were reviewed with the patient. -preservative-free artificial tears as needed. -briefly discussed ce/iol on DATE_TIME; patient may book at next visit; phaco/istent or phaco/kdb candidate. -long discussion with patient on DATE_TIME: given high iop os, possible progression on oct confirmed os, bat 20/500 os, and c/o decreased vision os, we proceeded with a phaco/ecp/istent os first on DATE_TIME. -long discussion with patient on DATE_TIME: given iop asymmetry and good response os to phaco/ecp/istent, we proceeded with phaco/ecp/istent od on DATE_TIME. -rtc in DATE_TIME iop check, dilation, and disc photos ou, sooner prn. consider yag capsulotomy os/od when patient is bothered by his vision os/od. the information above was documented by Person as a scribe for PERSON on DATE_TIME.",
"gpt4_summary": "The patient's intraocular pressure is at goal in both eyes and they are not on glaucoma medications. Phaco/istent treatments are proposed. Blood glucose, BP and cholesterol control is crucial. Retinal detachment measures were discussed.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09921",
"image_path": "slo_fundus_09921.jpg",
"filename": "data_09921.npz",
"report": "Patient has left occipital porencephalic cyst, right homonymous hemianopia (related to the cyst), and bilateral optic atrophy. There's unexpected rnfl loss, suggesting a non-cyst related issue. Glaucoma not mentioned.",
"age": 46.94,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "for reversible causes of optic neuropathies although my suspicion is low. impression: 1. left occipital porencephalic cyst 2. right homonymous hemianopia -secondary to #1 3. bilateral optic atrophy -mostly explained by transynaptic degeneration from #1 -? superimposed temporal vf with correlating rnfl loss os - not expected from #1 -rule out compressive lesion . recommendations: 1. mri brain and orbits c+ c- 2. obtain cbc, lyme, fta, b12, folate, mma, homocystein 3. follow up depending on the results of #1-2. it is a pleasure to participate in the care of this patient. please do not hesitate to call with questions. ? sincerely, ? PERSON, PERSON spent DATE_TIME with this patient, more than 50% of which was face to face with the patient.",
"gpt4_summary": "Patient has left occipital porencephalic cyst, right homonymous hemianopia (related to the cyst), and bilateral optic atrophy. There's unexpected rnfl loss, suggesting a non-cyst related issue. Glaucoma not mentioned.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09923",
"image_path": "slo_fundus_09923.jpg",
"filename": "data_09923.npz",
"report": "46 y/o male has neurofibromatosis type 1, bicuspid aortic valve, and mitral valve prolapse. He also has pigment dispersion syndrome, is a glaucoma suspect but doesn't have glaucoma currently. History of herpes zoster ophthalmicus. Under observation.",
"age": 46.79,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "46 y.o. male with h/o bicuspid aortic valve, mitral valve prolapse, neurofibromatosis type 1 - atypical pigmented (mostly episcleral) lesion os eastern NRP descent. nonsmoker no change from prior size measurements or compared to prior photos DATE_TIME >> observe - neurofibromatosis type 1 with non-enhancing t2 hyperintense lesion in genu of corpus callosum suggestive of low-grade glioma followed by dr. PERSON he has had asymmetric proptosis os>od without significant change since DATE_TIME (~3-4mm difference between os and od). no orbital lesions noted on orbital mri DATE_TIME and followup brain PERSON (last DATE_TIME). no evidence of optic neuropathy (stable visual acuity, color vision, and hvf) >> continue to monitor - pigment dispersion syndrome/glaucoma suspect ou tmax: 16/17 cct: 563/562 gonio DATE_TIME: ou open to cbb, 2+ pigmented tm hvf DATE_TIME: ou likely full DATE_TIME: ou reliable and full DATE_TIME: od nonspecific superior defects, os full rnfl DATE_TIME: PERSON, os thin n DATE_TIME: PERSON, os thin n DATE_TIME: PERSON, os thin n (likely stable from DATE_TIME) disc photos: DATE_TIME last dilated: DATE_TIME previously followed by dr. PERSON then PERSON; no glaucoma at this time though tilted nerves reduce oct reliability. monitor iop (still ok but slightly increased from prior) >> monitor off eyedrops - likely physiologic anisocoria os>od asymmetry similar in light and dark; has been present since first exam here in DATE_TIME >> monitor - h/o herpes zoster ophthalmicus os (DATE_TIME) noted lesions on left nasal bridge and upper lid near brow no ocular involvement at the time >> observe f/up DATE_TIME with mrx, rnfl oct, dilation, sooner prn discussed q6month followup to monitor iop in setting of pigment dispersion",
"gpt4_summary": "46 y/o male has neurofibromatosis type 1, bicuspid aortic valve, and mitral valve prolapse. He also has pigment dispersion syndrome, is a glaucoma suspect but doesn't have glaucoma currently. History of herpes zoster ophthalmicus. Under observation.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09926",
"image_path": "slo_fundus_09926.jpg",
"filename": "data_09926.npz",
"report": "The patient is taking cod liver oil and alendronate (fosamax). They have undergone laser iridotomy in both eyes, suggesting treatment for glaucoma. Other conditions include osteoporosis, depressive disorder, dyslipidemia, smoker, hemorrhoids and more.",
"age": 72.18,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "cod liver oil cap (taking) dose: 1 tbsp; form: not available; route: PERSON; frequency: qd; directions: not available; details: not available; date: DATE_TIME PERSON DATE_TIME DATE_TIME needs PERSON. metal med transfer process. alendronate (fosamax) 70 mg tablet take 1 tablet (70 mg total) by mouth DATE_TIME. take in DATE_TIME with a full glass of water, on an empty stomach, and do not take anything else by mouth or lie down for DATE_TIME. your orders future appointments provider department dept phone DATE_TIME DATE_TIME PERSON, LOCATION shore physicians group PHONE_NUMBER future orders complete by expires laser iridotomy - od - right eye as directed DATE_TIME laser iridotomy - os - left eye as directed DATE_TIME orders placed this visit humphrey visual field - ou - both eyes oct, optic nerve - ou - both eyes - condition list as of DATE_TIME depressive disorder dyslipidemia smoker hemorrhoids osteoporosis centrilobular emphysema bronchiectasis without complication preventive measure atherosclerotic vascular disease results summary immunizations administered on date of encounter - DATE_TIME none",
"gpt4_summary": "The patient is taking cod liver oil and alendronate (fosamax). They have undergone laser iridotomy in both eyes, suggesting treatment for glaucoma. Other conditions include osteoporosis, depressive disorder, dyslipidemia, smoker, hemorrhoids and more.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09929",
"image_path": "slo_fundus_09929.jpg",
"filename": "data_09929.npz",
"report": "The patient has glaucoma, treated with latanoprost. There's an inferior defect and dense quadrantanopsia in both eyes, with a moderate cataract becoming visually significant. No diabetic retinopathy present. The patient has Fuchs dystrophy and migraines.",
"age": 78.77,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "DATE_TIME. female 1. PERSON, on lumigan and PERSON DATE_TIME, c:d asymmetry od>os - changed from lumigan to latanoprost due to cost; PERSON stopped DATE_TIME to decrease risk of endo toxicity from cai in the setting of fuchs fhx negatives tmax 23 per old records cct 567, 548 (average ou) hvf od left sided inferior defect, dense quadrantanopsia hvf os left sided inferior dense quadrantanopsia, stable c/w (new in DATE_TIME) oct od: wnl oct os: borderline inferior thinning stable ou dp stable iop controlled ou (tgoal mid-upper teens) plan: cpm with latanoprost ou qhs 2. moderate cataract is present that is becoming visually significant. refer to cornea given guttae 3. diabetes: no evidence of diabetic retinopathy on dfe. blood sugar and blood pressure control encouraged. 4. fuchs dystrophy ou cct 567, 548 (average ou), stable (560's in past visit) stable, observe no am blur 5. migraine aura, observe 6. bilateral PERSON left sided PERSON, present on hvf ou from DATE_TIME, new as compared to prior visual field from DATE_TIME pt was hospitalized for high bp (NRP) around that time pt denies neurologic sx except for a bad ha at the time upon further reflection about this time, pt reports word finding difficulty and possible visual hallucinations/flashing in her vision pt had ct scan in hospital and mri which she reports were normal. letter to pcp f/u 6 months va and iop ou letter to PERSON. PERSON (cardiology)",
"gpt4_summary": "The patient has glaucoma, treated with latanoprost. There's an inferior defect and dense quadrantanopsia in both eyes, with a moderate cataract becoming visually significant. No diabetic retinopathy present. The patient has Fuchs dystrophy and migraines.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09931",
"image_path": "slo_fundus_09931.jpg",
"filename": "data_09931.npz",
"report": "The note is regarding an upcoming neuro-ophthalmology appointment. There is no specific mention of glaucoma in the note. The patient is advised about possible effects of pupil dilation.",
"age": 75.62,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "DATE_TIME PERSON dear mr. PERSON a grass: we thank you for choosing Institution for your care and we look forward to welcoming you for your appointment on DATE_TIME at DATE_TIME with dr. PERSON. our neuro-ophthalmology suite is located on the 9th floor of the Institution. we ask patients to allow DATE_TIME for a first appointment. if you have any questions or concerns, please contact our office at PHONE_NUMBER. please be aware that your pupils might need to be dilated for your exam. dilation of your pupils will produce blurred vision for at least 2-3 hours, and it will make your eyes sensitive to light. these effects can make it difficult, or unsafe, to drive a car. as such, it is advisable to attend your appointment with someone who can drive, or at least you should be prepared to remain in the area until you believe your vision has returned to normal. * reminder: if you have had a previous mri of your brain or orbits, please hand carry the cd of the images to your appointment. sincerely, naomi francisque administration assistant",
"gpt4_summary": "The note is regarding an upcoming neuro-ophthalmology appointment. There is no specific mention of glaucoma in the note. The patient is advised about possible effects of pupil dilation.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09942",
"image_path": "slo_fundus_09942.jpg",
"filename": "data_09942.npz",
"report": "The clinical note lists multiple health conditions: hypertensive disorder, hypercholesterolemia, joint pain, anemia, vitamin D deficiency, hypothyroidism, osteopenia, type 2 diabetes, sleep apnea, shortness of breath, obesity, and loose stools. There is no mention of glaucoma.",
"age": 63.61,
"gender": "female",
"race": "asian",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "m althausen m plante, LOCATION 5:04 pm received from: partners lmr received sig: dose: 81 mg; form: take 1 tablet; route: PERSON; frequency: qd; directions: not available; details: dispense: tablet(s); status: active; source: PERSON,PERSON; date: DATE_TIME atenolol (tenormin) 50 mg tablet take 1 tablet (50 mg total) by mouth DATE_TIME. cholecalciferol, vitamin d3, (vitamin d3 oral) take by mouth. 1000 unit 1 oral bid. PERSON DATE_TIME needs PERSON. metal med transfer process, from oncall cyclobenzaprine (flexeril) 10 mg tablet take 1 tablet (10 mg total) by mouth 3 (three) times a day as needed for muscle spasms. levothyroxine (synthroid, levothroid) 75 mcg tablet take 1 tablet (75 mcg total) by mouth DATE_TIME. onetouch ultra test strp strips 1 each by miscellaneous route as needed. oxiconazole (LOCATION) 1 % lotion apply topically 2 (two) times a day. simvastatin (zocor) 20 mg tablet dose: 20 mg; form: take 1 tablet; route: PERSON; frequency: qpm; directions: not available; details: duration: 90 day(s); dispense: 90 tablet(s); status: active; source: agarwal-harding,PERSON.; date: DATE_TIME PERSON DATE_TIME received from: partners lmr condition list as of DATE_TIME hypertensive disorder hypercholesterolemia multiple joint pain anemia vitamin d deficiency hypothyroidism osteopenia type 2 diabetes mellitus obstructive sleep apnea syndrome shortness of breath obesity loose stools results summary immunizations administered on date of encounter - DATE_TIME none",
"gpt4_summary": "The clinical note lists multiple health conditions: hypertensive disorder, hypercholesterolemia, joint pain, anemia, vitamin D deficiency, hypothyroidism, osteopenia, type 2 diabetes, sleep apnea, shortness of breath, obesity, and loose stools. There is no mention of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09946",
"image_path": "slo_fundus_09946.jpg",
"filename": "data_09946.npz",
"report": "52-year-old white, non-Hispanic male. No glaucoma diagnosis. Retina checkup scheduled in 6 months. Managed by comprehensive ophthalmology.",
"age": 52.01,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "a 52 y.o. white, non-hispanic male with no diagnosis of glaucoma. with retina in 6m as planned _____________________ \u00ff PERSON, md, mph comprehensive ophthalmology LOCATION",
"gpt4_summary": "52-year-old white, non-Hispanic male. No glaucoma diagnosis. Retina checkup scheduled in 6 months. Managed by comprehensive ophthalmology.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09947",
"image_path": "slo_fundus_09947.jpg",
"filename": "data_09947.npz",
"report": "Post cataract surgery and YAG laser caps treatment. Glaucoma suspected due to cupping and previous elevated IOP, now controlled with Xalatan. No macular edema.",
"age": 87.65,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "imp: s/p cataract surgery and yag laser caps ou erm od>os - oct mac no striae/edema glaucoma suspect ou; cupping ou and prev iop elev od - iop now controlled on xalatan ou qhs - normal oct and hvf DATE_TIME blepharitis/dry ou refr error plan: cpm PERSON/art tears prn 6 mo exam",
"gpt4_summary": "Post cataract surgery and YAG laser caps treatment. Glaucoma suspected due to cupping and previous elevated IOP, now controlled with Xalatan. No macular edema.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09949",
"image_path": "slo_fundus_09949.jpg",
"filename": "data_09949.npz",
"report": "34 y.o. suspect for glaucoma in both eyes due to enlarged c/d ratio. No family history or trauma. High myopia as a risk factor. Stable vision, open gonioscopy. No history of glaucoma medication. Suggested further testing. Mild vision distortion.",
"age": 34.52,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "34 y.o. glaucoma suspect, both eyes - 2/2 to enlarged c/d ratio and borderline PERSON DATE_TIME 22/22 - risk factors: no family history, no trauma/steroids, average cct - tmax: 26 from DATE_TIME - hvf 24-2 DATE_TIME (bmc): reliable and full ou DATE_TIME: reliable and full ou DATE_TIME: reliable and full ou - stable DATE_TIME: reliable and full ou -- stable - oct rnfl DATE_TIME (bmc): 8/10 qual ou, 88 right eye, DATE_TIME left eye, mostly full DATE_TIME: od 87 os 88, PERSON ou DATE_TIME: od 85 os 88, PERSON ou - stable DATE_TIME: od 85 os 85 PERSON ou -- stable - gonioscopy : open to cbb with posterior bowing peripherally with no tid and no significant pigmentation or k spindle. - cct 531/532 - photos done DATE_TIME - drops: never been on drops for glaucoma > observe, repeat testing in DATE_TIME high myopia ou > rd precautions > new rx given per patient request floaters os, some new od - no tears/holes/subretinal fluid/rd > rd precautions mild distortion of vision os - reported 'wavy reflection' in lower quadrant of vision os - corrects to 20/20, macula flat, good foveal reflex > artificial tears fu DATE_TIME mrx, dilate, hvf/ oct",
"gpt4_summary": "34 y.o. suspect for glaucoma in both eyes due to enlarged c/d ratio. No family history or trauma. High myopia as a risk factor. Stable vision, open gonioscopy. No history of glaucoma medication. Suggested further testing. Mild vision distortion.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09952",
"image_path": "slo_fundus_09952.jpg",
"filename": "data_09952.npz",
"report": "The clinical note doesn't mention the presence of glaucoma. The patient's conditions include intracranial meningioma, otalgia, breast lump, migraines, s/p laparoscopic cholecystectomy, multiple thyroid nodules, and iga deficiency.",
"age": 34.82,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "date of birth: DATE_TIME patient mrn: NUMBER Institution neuro oph LOCATION dept phone #: PHONE_NUMBER dept fax #: PHONE_NUMBER DATE_TIME office visit mrn: NUMBER provider: PERSON, PERSON: address phone e-mail address PHONE_NUMBER (home) PHONE_NUMBER (work) PHONE_NUMBER (mobile) EMAIL_ADDRESS information date of birth sex race ethnicity preferred language preferred written language DATE_TIME female white or NRP no NRP NRP future appointments provider department center DATE_TIME 10:00 am PERSON r LOCATION, PERSONtitution pappas center for neuro oncology DATE_TIME 10:00 am PERSON, PERSONtitution neuro oph main campus Institution main reason for visit none vital signs/measurements smoking status light tobacco smoker no eyeglass prescription found allergies as of DATE_TIME sulfa (sulfonamide antibiotics) medications and orders your current medications citalopram (celexa) 10 mg tablet take 10 mg by mouth DATE_TIME. oxcarbazepine (trileptal) 150 mg tablet take 1 tablet (150 mg total) by mouth 2 (two) times a day. propranolol (inderal la) 80 mg 24 hr capsule take 1 capsule (80 mg total) by mouth DATE_TIME. condition list as of DATE_TIME intracranial meningioma otalgia breast lump migraine with aura and without status migrainosus, not intractable s/p laparoscopic cholecystectomy multiple thyroid nodules iga deficiency smoker results summary immunizations administered on date of encounter - DATE_TIME none",
"gpt4_summary": "The clinical note doesn't mention the presence of glaucoma. The patient's conditions include intracranial meningioma, otalgia, breast lump, migraines, s/p laparoscopic cholecystectomy, multiple thyroid nodules, and iga deficiency.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09956",
"image_path": "slo_fundus_09956.jpg",
"filename": "data_09956.npz",
"report": "63-year-old patient, with a history of breast cancer, gerd, bronchiectasis, and cataract, last saw the doctor for an urgent eval. The patient has dry eye, uses artificial tears. Mild c/d asymmetry indicates possibility of glaucoma.",
"age": 64.45,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "63 yo chef/caterer (works in LOCATION ) with history of breast cancer, gerd with periodic mac bronchiectasis, forehead bcc removed in DATE_TIME, cholelithiasis \u00ff her brother is a cardiologist. son URLugman, now successful instagrammer and daughter DATE_TIME. plays tennis 3x/wk DATE_TIME plans culinary tourism trips \u00ff pt of dr. PERSON, last seen by dr. PERSONME, then me 10/16 for urgent des eval \u00ff last saw me DATE_TIME \u00ff 1. dry eye / meibomian gland dysfunction - now only using ats as needed. - can add warm compresses, lid hygiene - already using fish oil \u00ff 2. cataracts (no1nc1 ou) >> mrx given - refracts to 20/20 \u00ff 3. history of breast cancer s/p unilateral lumpectomy 1/05, s/p xrt (3/05), started tamoxifen 3/05 and now off-- completed DATE_TIME, now off meds - no changes in vision, no metamorphopsia. \u00ff 4. mild c/d asymmetry od>os (0.6/0.4), in setting of larger PERSON -intact rims ou, no fhx cct 527/532-- iop likely higher than measured \u00ff hvf 10/19:od reliable and full; os 3/10fl and 21%fp; termporal scattered defects hvf 6/18: od 7/11 fl, scattered defects, os reliable and full hvf DATE_TIME: high false positives ou. full ou hvf DATE_TIME: high false positives ou. likely unreliable od, wnl os \u00ff oct 10/19: rims intact ou DATE_TIME: rims intact ou DATE_TIME: wnl ou, stable DATE_TIME: PERSON ou observe \u00ff plan: followup in DATE_TIME, sooner prn _____________________ PERSON, md comprehensive ophthalmology LOCATION",
"gpt4_summary": "63-year-old patient, with a history of breast cancer, gerd, bronchiectasis, and cataract, last saw the doctor for an urgent eval. The patient has dry eye, uses artificial tears. Mild c/d asymmetry indicates possibility of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09959",
"image_path": "slo_fundus_09959.jpg",
"filename": "data_09959.npz",
"report": "The patient has a non-visually significant cataract, a refractive error for which glasses have been prescribed, and a pterygium. There's a suspicion of glaucoma based on increased c:d ratio and slightly thin cct. Diabetes is managed, with no retinopathy observed.",
"age": 69.52,
"gender": "male",
"race": "white",
"ethnicity": "unknown",
"language": "english",
"maritalstatus": "married or partnered",
"note": "68 PERSON here for PERSON testing speaks NRP, interpreter present 1. diabetes: no evidence of diabetic retinopathy on last exam. blood sugar, blood pressure, and cholesterol control encouraged. URLd cataract is present ou that is not visually significant. observation at this time was recommended. 3. refractive error: a prescription for new glasses was given to the patient DATE_TIME. 4. pterygium od, nvs, observe 5. NRP suspect ou based on inc c:d ratio fhx mgf lost vision (? cause) cct slightly thin (514,514) hvf full ou oct PERSON, borderline os gonio open ou iop controlled observe DATE_TIME, mrx, iop, hvf, LOCATION, oct and dp stacey c Person scribing for dr. Person i was present while this encounter was recorded and agree that the information entered by my scribe is complete and accurate.",
"gpt4_summary": "The patient has a non-visually significant cataract, a refractive error for which glasses have been prescribed, and a pterygium. There's a suspicion of glaucoma based on increased c:d ratio and slightly thin cct. Diabetes is managed, with no retinopathy observed.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09965",
"image_path": "slo_fundus_09965.jpg",
"filename": "data_09965.npz",
"report": "63 y.o. patient with a. fib; narrow, non-occludable angles; optic disc cupping; excellent intraocular pressure; cct 552/565. Glaucoma risk low. Presence of NS cataract, refractive error.",
"age": 63.75,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "63 y.o. with a. fib on eliquis here for testing only narrow angles ou, not occludable - hyperopic - angle closure symptoms discussed > monitor, repeat gonioscopy next visit optic disc cupping ou - no family hx - excellent iop - cct 552/565 - photos done DATE_TIME PERSON ou - hvf DATE_TIME full ou > low risk. observe nuclear sclerotic cataract ou - not visually significant > observe refractive error > updated glasses prescription given per request last visit fu DATE_TIME, mrx, gonio, dilate",
"gpt4_summary": "63 y.o. patient with a. fib; narrow, non-occludable angles; optic disc cupping; excellent intraocular pressure; cct 552/565. Glaucoma risk low. Presence of NS cataract, refractive error.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09966",
"image_path": "slo_fundus_09966.jpg",
"filename": "data_09966.npz",
"report": "35-year-old myopic male with history of pigmentary dispersion syndrome and glaucomatous optic neuropathy, diagnosed with pds glaucoma. His vision is stable, with no pain reported. Previously on timolol, it was ineffective and caused weakness. His current plan includes dorzolamide and latanaprost. Previously was a runner, experienced blurry vision post-run. Noted family history of glaucoma.",
"age": 35.19,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "resident assessment and plan 35 yo myopic male previously followed by PERSON PERSON, originally referred for evaluation and LOCATION of pds glaucoma ou from PERSON (dr. PERSON). was diagnosed DATE_TIME, was on timolol with iops in teens, but iop continued to increase. alternative LOCATION are discussed. +fh of poag (grandfather). t max per pt is low DATE_TIME. vision is stable, no eye pain. states that he used to be a runner, but usually had very blurry vision after the run. no sulfa allergy, no asthma. no h/o trauma or steroid use. timolol caused weakness/tiredness, also, ineffective, felt better without it 1. pigmentary dispersion syndrome with glaucomatous optic neuropathy os, suspect PERSON/o blurry vision/eye pain after extensive running (episodes of pigmentary storm) - t max per pt - low DATE_TIME without LOCATION, had been in mid teens on timolol for DATE_TIME, but couldn't tolerate due to weakness. - cct 529/538 (thinner) - DATE_TIME hvf/oct rfnl od wnl, large nerve; os - significant cupping with glaucomatous damage, stable. - iop goal od mid/high teens; os - mid/low teens, csm rtc: DATE_TIME plan:- cont dorzolomide bid (started by outside physician) - cont latanaprost ou qhs 2. myopia ou - ok with current glasses - see above cc. PERSON PERSON (LOCATION)",
"gpt4_summary": "35-year-old myopic male with history of pigmentary dispersion syndrome and glaucomatous optic neuropathy, diagnosed with pds glaucoma. His vision is stable, with no pain reported. Previously on timolol, it was ineffective and caused weakness. His current plan includes dorzolamide and latanaprost. Previously was a runner, experienced blurry vision post-run. Noted family history of glaucoma.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09967",
"image_path": "slo_fundus_09967.jpg",
"filename": "data_09967.npz",
"report": "The patient has a history of high myopia and is suspected for primary open angle glaucoma due to an increased cup-to-disc ratio. The patient's sister has undergone surgery and is on glaucoma drops.",
"age": 49.52,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "h/o high myopia h/o glaucoma suspect 1. primary open angle glaucoma suspect ou based on increased c:d ratio ou fhx + sister s/p surgery and on drops for glaucoma gonio open ou hvf full ou oct wnl ou dp DATE_TIME stable iop controlled ou observe 2. flashes od no retinal tears/holes/rd on exam rd warnings d/w patient 3. high myopia ou rd warnings mrx given for new glasses. 4. rare PERSON wear (special occasions only) cl hygiene f/u DATE_TIME, mrx, iop, hvf, cct, dilate, oct/dp",
"gpt4_summary": "The patient has a history of high myopia and is suspected for primary open angle glaucoma due to an increased cup-to-disc ratio. The patient's sister has undergone surgery and is on glaucoma drops.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09977",
"image_path": "slo_fundus_09977.jpg",
"filename": "data_09977.npz",
"report": "28 y.o. male with a history of myopia, blepharitis, and recurrent hordeolum. Large c:d. No history of ocular hypertension. Intraocular pressure 12/12. No glaucoma, indicated by normal HVF and RNFL OCT.",
"age": 28.68,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "28 y.o. m, new patient, here for evaluation of large c:NRP pohx: myopia, large c:d, recurrent hordeolum, blepharitis pmh: none # large c:d, os > od - unknown fhx (adopted) - cct 512/514 - hvf wnl - rnfl oct wnl - iop 12/12; no history of ohtx - most likely physiologic cupping, low risk > follow up in DATE_TIME # refractive error - last mrx DATE_TIME # blepharitis - warm compresses, lid hygiene - fatty fish/omega 3 supplementation discussed # history of ocular migraine - resolved fu DATE_TIME, mrx, dilate i saw and evaluated this patient and discussed the case as appropriate with the resident. i have reviewed the resident's notes and made any necessary changes. PERSON",
"gpt4_summary": "28 y.o. male with a history of myopia, blepharitis, and recurrent hordeolum. Large c:d. No history of ocular hypertension. Intraocular pressure 12/12. No glaucoma, indicated by normal HVF and RNFL OCT.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09978",
"image_path": "slo_fundus_09978.jpg",
"filename": "data_09978.npz",
"report": "The 63 year old patient suffers from occasional flashing lights in peripheral vision, cataracts, refractive error and choroidal nevi. Prescription for new glasses given. Noted as glaucoma suspect, with no family history, normal IOP and healthy c/d.",
"age": 63.64,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "63 yo last seen by me DATE_TIME, by dr. PERSON retired teacher 1. occasional flashing lights in peripheral vision, only at DATE_TIME; stable floaters - retinal detachment precautions discussed. patient will contact our office immediately for new flashing lights, floaters or a curtain coming over the vision; if unable to get appointment to be seen or during non-business hours, patient will go to Institution ew at 243 NRP street for exam. \u00ff\u00ff 2. cataracts od>os - cortical changes od - more trouble at DATE_TIME driving in the rain 3. refractive error: - a prescription for new glasses was given to the patient DATE_TIME. \u00ff\u00ff 4. 2 episodes of darkening of PERSON past; since last visit 1 time\u00ff-- resolved \u00ff note from dr. PERSON: situation discussed with patient; in my experience monocular visual changes on awakening are often explained by differences in dark adaptation between the two eye, i.e. one eye was covered and the other was not. unless her symptoms change, i would not recommend further work-up. \u00ff 5. choroidal nevi ou - small and flat od - 2 dd with ring of drusen os; PERSON taken; no elevation, no orange pigment\u00ff - bscan DATE_TIME: technique: closed lids. contour: within normal limits. lens: phakic. vitreous: interfaces, low reflective. lesion: dome, superior. LOCATION echo pattern: within normal limits. notes a small dome shaped elevation is seen superiorly measuring approximately <1.0mm. - observe \u00ff 6. glaucoma suspect - no family history - iop ok - large c/d by symmetric and healthy appearing - cct 545, 546 -rnfl DATE_TIME: full rims ou - hvf DATE_TIME: reliable and full \u00ff followup: DATE_TIME; DATE_TIME for testing (DATE_TIME) _____________________ PERSON, md, mph comprehensive ophthalmology LOCATION",
"gpt4_summary": "The 63 year old patient suffers from occasional flashing lights in peripheral vision, cataracts, refractive error and choroidal nevi. Prescription for new glasses given. Noted as glaucoma suspect, with no family history, normal IOP and healthy c/d.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09979",
"image_path": "slo_fundus_09979.jpg",
"filename": "data_09979.npz",
"report": "The 70 y.o. female is a glaucoma suspect with intraocular pressure (IOP) okay currently, but has past history of high myopia. She also has had retinal detachments, diabetic retinopathy, and mild refractive error.",
"age": 70.99,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "other",
"maritalstatus": "unknown",
"note": "70 y.o. f here for follow-up \u00ff\u00ff 1. PERSON toric LOCATION (os DATE_TIME, od DATE_TIME) doing well, happy with vision s/p yag cap os DATE_TIME s/p yag cap od DATE_TIME 2. dm excellent control s/p weight loss no diabetic retinopathy continue good bs/bp control continues DATE_TIME eye exams \u00ff\u00ff 3. glaucoma suspect iop ok today large c/d ratio but used to have high myopia prior to ce, possibly myopic discs DATE_TIME: borderline sup thinning od oct rnfl DATE_TIME: normal ou oct rnfl DATE_TIME: od normal/ os borderline sup thin pachy 575/571, true iop a little lower than measured hvf DATE_TIME: normal ou, reliable hvf DATE_TIME: os with possible small nasal defect hvf DATE_TIME: od full os: sup temporal defect/ enlarged blind spot, likely related to retinal scar from LOCATION repair 4. posterior vitreous detachment ou retinal detachment precautions were reviewed with the patient in detail including increase in and/or change in floaters, worsening flashing lights, and curtains or shadows \u00ff\u00ff 5. mild refractive error/presbyopia - currently just wears otc readers \u00ff 6. retinal flap tear os after yag capsulotomy, treated with laser by dr. kylstra then developed retinal detachment os, s/p ppv/el/fax/14%c3f8 os for mac-on rd (wang/kylstra), DATE_TIME. looks good; retina attached. small branch retinal vein occlusion adjacent to area of laser/ retinotomy (noted by URLlstra, stable compared to photos seeing dr. PERSON now, has appointment in DATE_TIME \u00ff",
"gpt4_summary": "The 70 y.o. female is a glaucoma suspect with intraocular pressure (IOP) okay currently, but has past history of high myopia. She also has had retinal detachments, diabetic retinopathy, and mild refractive error.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09981",
"image_path": "slo_fundus_09981.jpg",
"filename": "data_09981.npz",
"report": "Patient to have cataract and trabeculectomy surgery on the left eye. Diagnosed with severe pigmentary glaucoma and age-related nuclear cataract. Not on blood thinners.",
"age": 75.92,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "please schedule this patient (PERSON ) for surgery: cataract and trabeculectomy laterality: left eye surgeon: PERSON, LOCATION level: 2 diagnoses associated with this procedure for booking: pigmentary glaucoma of left eye, severe stage; age-related nuclear cataract of left eye anesthesia: mac plus topical and sub-tenon's block case duration: DATE_TIME operating time blood thinners: this patient is not on blood thinners please send me confirmation message with the date when scheduled. thank you!",
"gpt4_summary": "Patient to have cataract and trabeculectomy surgery on the left eye. Diagnosed with severe pigmentary glaucoma and age-related nuclear cataract. Not on blood thinners.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09984",
"image_path": "slo_fundus_09984.jpg",
"filename": "data_09984.npz",
"report": "The 79-year-old patient has been referred for a glaucoma evaluation. They have moderate stage glaucoma in their right eye but no history of asthma, trauma, or steroid use. The patient wants to switch from Lumigan to generic latanaprost due to cost.",
"age": 79.7,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "79 PERSON referred by PERSON for glaucoma eval. no fh, no steroid use, no trauma, no sulfa allergy. no h/o asthma, lost f/u since DATE_TIME 1. poag od moderate stage, PERSON 34 od (post op) and 21 os - gonio: open - has been in mid/high teens on pg and timolol od. - t goal od mid/low teens, os mid/high teens, at goal - hvf od DATE_TIME: has high ltfs over DATE_TIME, appears stable. os - stable early changes. - oct rnfl with artifacts DATE_TIME, but appears stable. long discussion was done about nature of the disease, visual prognosis and management options, all questions answered. wants to switch to generic latanaprost from lumigan due to cost. plan; cont timolol gel 0.5% od only qam stop lumigan, start latanaprost ou qhs rtc: DATE_TIME for iop only longwood 2. pseudophakia ou, DATE_TIME - stable - per dr. PERSON 3. erm ou - stable",
"gpt4_summary": "The 79-year-old patient has been referred for a glaucoma evaluation. They have moderate stage glaucoma in their right eye but no history of asthma, trauma, or steroid use. The patient wants to switch from Lumigan to generic latanaprost due to cost.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09985",
"image_path": "slo_fundus_09985.jpg",
"filename": "data_09985.npz",
"report": "The patient has narrow angles, underwent laser peripheral iridotomy (LPI) and phacoemulsification in both eyes, and shows mild optic nerve cupping. They're considered a low risk suspect for narrow angle glaucoma. Tests show mild thinning in the eye. No evidence of tropia or phoria. Dry eye is present and may be causing monocular diplopia.",
"age": 73.78,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "single",
"note": "# narrow angles, s/p lpi ou and now phaco ou, mild on cupping ou/narrow angle glaucoma suspect low risk ou: PERSON:none/ steroids: none/ trauma: none prior surgery: lpi ou, ce/iol ou (DATE_TIME) med intolerance: none ttarget: 20 /20 , tmax: ( ) / ( ) cct: / gonioscopy: rnfl oct shows mild thinning inf/temp od, wnl os gcc shows inferior thinning od, diffuse thinning worse PERSON DATE_TIME) wnl ou # pseudophakia ou (DATE_TIME) # dry eye od> os likely causing monocular diplopia, intermittent no evidence of tropia or phoria of cross over test DATE_TIME; eoms are full use at qid patient to pay attention to symptoms and report back plan: vf od likely stable compared to DATE_TIME, os appears worse but does fluctuate possible artifact from lens rim continue to observe off drops ; nerve appearance is reassuring , as is iop follow up DATE_TIME with repeat hvf ou, os first , pachymetry, gonio \u00ff",
"gpt4_summary": "The patient has narrow angles, underwent laser peripheral iridotomy (LPI) and phacoemulsification in both eyes, and shows mild optic nerve cupping. They're considered a low risk suspect for narrow angle glaucoma. Tests show mild thinning in the eye. No evidence of tropia or phoria. Dry eye is present and may be causing monocular diplopia.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09988",
"image_path": "slo_fundus_09988.jpg",
"filename": "data_09988.npz",
"report": "The patient's eye examination shows normal visual fields, vitreous condensation, and no optic nerve damage, ruling out glaucoma. Symptoms may be due to migraines or vitreous floaters.",
"age": 54.72,
"gender": "male",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "divorced",
"note": "continues to be excellent, including automated visual fields. fundi have a normal appearance, though he does have prominent vitreous condensation od>os. oct does not show any evidence of optic nerve damage. given his history of hypercoagulability and the recent eye exam findings, i obtained fluorescein angiogram, which was reassuring. my overall impression continues to be that some of his symptoms are migrainous in origin. however, some may also be related to vitreous floaters. being a visual artist, he is particularly attuned to visual changes. my plan is: - no migraine prophylactic at this point - apixaban as per hematology - upcoming appointment in retina with dr. PERSON we have not scheduled further follow-up but i am happy to see the patient again if the need arises. thank you for allowing me to participate in the care of your patient. ???? ??please do not hesitate to call with questions. ? sincerely, ? PERSON, LOCATION neuro-ophthalmology, headache unit, and inflammatory neuro-ophthalmology/skull base disorders clinic. division of neuroimmunology, Institution neuro-ophthalmology, Institution ? note: greater than half of this DATE_TIME visit was spent counseling the patient on the medical condition or coordinating care. this time excludes any listed procedures.",
"gpt4_summary": "The patient's eye examination shows normal visual fields, vitreous condensation, and no optic nerve damage, ruling out glaucoma. Symptoms may be due to migraines or vitreous floaters.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09989",
"image_path": "slo_fundus_09989.jpg",
"filename": "data_09989.npz",
"report": "The patient was diagnosed with normal tension glaucoma but had no progression, even after stopping eye drops around 2013. The patient has a family history of glaucoma but no history of eye trauma or long-term steroids use. They do not have any glaucoma medication issues. They also have vertical diplopia, blepharitis, and rosacea. They are continuously monitored.",
"age": 63.3,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "PERSON is a DATE_TIME DATE_TIME patient self-referred, first seen by dr. NRP on DATE_TIME. previously followed at the kellogg eye center # glaucoma suspect : due to enlarged c/d ratio. diagnosed DATE_TIME with normal tension glaucoma was on latanoprost qhs ou for many years with no progression on humphrey visual field stopped drops ~2013 with DATE_TIME monitoring, continued to have no progression risk factors: positive family history of glaucoma or blindness (grandmother, sister recently told glaucoma suspicion) , negative history of longterm steroids, negative history of eye trauma central corneal thickness: / (DATE_TIME)gonioscopy: open ou tmax: ( ) / ( ) mid teens here target iop: / not application refractive error wrx: od . . / os . . glaucoma procedures/lasers: none other eye procedures/lasers: none glaucoma medication issues: negative history of asthma negative history of bradycardia negative sulfa allergy negative history of renal disfuntion or kidney stones testing: baseline DATE_TIME (DATE_TIME) oct rnfl (DATE_TIME) hvf 24-2 ou # vertical diplopia: - diagnosed ~30 years ago - has been evaluated previously by neuro ophthalmologist - previously worked up with mri DATE_TIME, reportedly unremarkable - no history of trauma - prisms, optom to manage - recently had a refraction. # blepharitis and rosacea - comfortable DATE_TIME. asymptomatic. #social: moved to ma in DATE_TIME. previously lived in LOCATION, LOCATION. plan DATE_TIME: iop not recorded , *** od, *** os PERSON is here for dfe, humphrey visual field, and LOCATION. continue to monitor off therapy last dilated exam: DATE_TIME*** DATE_TIME rnfl: DATE_TIME*** last visual field:DATE_TIME*** baseline disc photos: DATE_TIME return to glaucoma clinic*** i, PERSON, am acting as scribe for dr. PERSON for patient PERSON on DATE_TIME. -",
"gpt4_summary": "The patient was diagnosed with normal tension glaucoma but had no progression, even after stopping eye drops around 2013. The patient has a family history of glaucoma but no history of eye trauma or long-term steroids use. They do not have any glaucoma medication issues. They also have vertical diplopia, blepharitis, and rosacea. They are continuously monitored.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09996",
"image_path": "slo_fundus_09996.jpg",
"filename": "data_09996.npz",
"report": "Patient has glaucoma, with right eye (OD) intraocular pressure above goal, left eye (OS) at the goal. Advised to start brimonidine, ensuring medication adherence, use artificial tears. Possible surgery for cataract.",
"age": 84.71,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "than or equal to 17 mmhg, right eye. -goal intraocular pressure less than or equal to 17 mmhg, left eye. -iop above goal od and at goal os on DATE_TIME off glaucoma medications. -start brimonidine bid od. -instructions written/typed/printed out for patient (see table/details under patient instructions). -emphasized adherence to medication regimen. -preservative-free artificial tears as neeed. -retinal detachment precautions were reviewed with the patient. -follow-up with dr. PERSON for refractive care. -follow-up with dr. PERSON for retina care. -rtc in DATE_TIME @ DATE_TIME with iop check ou, PERSON, bat od, optical biometry ou, hvf size v ou, dilation ou, and disc photos ou, sooner prn. we can consider pga qhs ou in future if progression or iop spike in either eye. good phaco/migs candidate od, but we can consider slt od (since patient is reluctant to undergo phaco => she believes it may have triggered wet amd os). i spent DATE_TIME with the patient, more than half of which was spent on counseling and coordination of care for this patient's glaucoma and cataract. the information above was documented by PERSON as a scribe for PERSON on DATE_TIME.",
"gpt4_summary": "Patient has glaucoma, with right eye (OD) intraocular pressure above goal, left eye (OS) at the goal. Advised to start brimonidine, ensuring medication adherence, use artificial tears. Possible surgery for cataract.",
"glaucoma": "yes",
"use": "test"
},
{
"id": "data_09998",
"image_path": "slo_fundus_09998.jpg",
"filename": "data_09998.npz",
"report": "57-year-old patient suspected of glaucoma underwent glaucoma tests. The oct and hvf on both eyes were normal with a non-specific defect revealed. A complete eye examination is advised.",
"age": 57.58,
"gender": "male",
"race": "black",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "57 URLleh/o glaucoma suspect, presents for glaucoma tests 1. glaucoma suspect ou >tcurrent: 12/12 >tmax: >tgoal: >c/d ratio: 0.7/0.6 >gonio: PERSON >cct: 529/530 >oct: DATE_TIME wnl ou >hvf: DATE_TIME full ou >family history: grandmother >race: af am >optic nerve photos DATE_TIME full rims ou oct and hvf 0n 9/17/20220, wnl oct: right eye reliability was good. left eye reliability was good. findings right eye normal left eye normal. hvf: hvf mean deviation (os) - left eye 1.26 hvf mean deviation (od) - right eye 2.04 right eye reliability/fixation was poor mean deviation was calculated to be: 2.04 db. interpretation of the testing revealed: non-specific defects left eye reliability/fixation was poor. mean deviation was calculated to be: 1.26 db. interpretation of the testing revealed: non-specific defects advised pt to have a complete eye examination, including dilation, on a DATE_TIME basis.",
"gpt4_summary": "57-year-old patient suspected of glaucoma underwent glaucoma tests. The oct and hvf on both eyes were normal with a non-specific defect revealed. A complete eye examination is advised.",
"glaucoma": "no",
"use": "test"
},
{
"id": "data_09999",
"image_path": "slo_fundus_09999.jpg",
"filename": "data_09999.npz",
"report": "Patient has pciol ou, toric os, pvd ou, and cupping os but no history of elevated IOP. Normal perimetry and OCT. No glaucoma mentioned.",
"age": 73.03,
"gender": "female",
"race": "white",
"ethnicity": "non-hispanic",
"language": "english",
"maritalstatus": "married or partnered",
"note": "imp: doing well with pciol ou (toric os) pvd ou cupping os; no hx iop elev; normal automated perimetry and optical coherence tomography now; PERSON refr error plan: rx=m 18 mo",
"gpt4_summary": "Patient has pciol ou, toric os, pvd ou, and cupping os but no history of elevated IOP. Normal perimetry and OCT. No glaucoma mentioned.",
"glaucoma": "no",
"use": "test"
}
]
================================================
FILE: data/test/report/iuxray_test.json
================================================
[
{
"id": "CXR3030_IM-1405",
"report": "Normal cardiomediastinal silhouette. There is no focal consolidation. There are no XXXX of a large pleural effusion. There is no pneumothorax. There is no acute bony abnormality seen.",
"image_path": [
"CXR3030_IM-1405/0.png",
"CXR3030_IM-1405/1.png"
],
"split": "test"
},
{
"id": "CXR38_IM-1911",
"report": "Lungs are clear. There is no pneumothorax or pleural effusion. The heart and mediastinum are within normal limits. Bony structures are intact.",
"image_path": [
"CXR38_IM-1911/0.png",
"CXR38_IM-1911/1.png"
],
"split": "test"
},
{
"id": "CXR3957_IM-2022",
"report": "Cardiac and mediastinal contours are within normal limits. The lungs are clear. Bony structures are intact.",
"image_path": [
"CXR3957_IM-2022/0.png",
"CXR3957_IM-2022/1.png"
],
"split": "test"
},
{
"id": "CXR621_IM-2203",
"report": "The heart, pulmonary XXXX and mediastinum are within normal limits. There is no pleural effusion or pneumothorax. There is no focal air space opacity to suggest a pneumonia. There are mild degenerative changes of the spine.",
"image_path": [
"CXR621_IM-2203/0.png",
"CXR621_IM-2203/1.png"
],
"split": "test"
},
{
"id": "CXR1347_IM-0225",
"report": "The cardiomediastinal silhouette is normal in size and contour. No focal consolidation, pneumothorax or large pleural effusion. Negative for acute displaced rib fracture.",
"image_path": [
"CXR1347_IM-0225/0.png",
"CXR1347_IM-0225/1.png"
],
"split": "test"
},
{
"id": "CXR2915_IM-1317",
"report": "The heart size is normal. The mediastinal contour is within normal limits. The lungs are free of any focal infiltrates. There are no nodules or masses. No visible pneumothorax. No visible pleural fluid. The XXXX are grossly normal. There is no visible free intraperitoneal air under the diaphragm.",
"image_path": [
"CXR2915_IM-1317/0.png",
"CXR2915_IM-1317/1.png"
],
"split": "test"
},
{
"id": "CXR34_IM-1644",
"report": "The heart is normal in size and contour. The lungs are clear, without evidence of infiltrate. There is no pneumothorax or effusion.",
"image_path": [
"CXR34_IM-1644/0.png",
"CXR34_IM-1644/1.png"
],
"split": "test"
},
{
"id": "CXR2590_IM-1083",
"report": "The heart is normal in size. The mediastinum is unremarkable. The lungs are clear.",
"image_path": [
"CXR2590_IM-1083/0.png",
"CXR2590_IM-1083/1.png"
],
"split": "test"
},
{
"id": "CXR1176_IM-0119",
"report": "The lungs and pleural spaces show no acute abnormality. Heart size and pulmonary vascularity within normal limits. .",
"image_path": [
"CXR1176_IM-0119/0.png",
"CXR1176_IM-0119/1.png"
],
"split": "test"
},
{
"id": "CXR738_IM-2296",
"report": "The heart and lungs have XXXX XXXX in the interval. Both lungs are clear and expanded. Heart and mediastinum normal.",
"image_path": [
"CXR738_IM-2296/0.png",
"CXR738_IM-2296/1.png"
],
"split": "test"
},
{
"id": "CXR2480_IM-1009",
"report": "The heart is normal in size and contour. There is no mediastinal widening. The lungs are clear bilaterally. No large pleural effusion or pneumothorax. The XXXX are intact.",
"image_path": [
"CXR2480_IM-1009/0.png",
"CXR2480_IM-1009/1.png"
],
"split": "test"
},
{
"id": "CXR3222_IM-1522",
"report": "The cardiomediastinal silhouette and pulmonary vasculature are within normal limits in size. The lungs are clear of focal airspace disease, pneumothorax, or pleural effusion. There are no acute bony findings.",
"image_path": [
"CXR3222_IM-1522/0.png",
"CXR3222_IM-1522/1.png"
],
"split": "test"
},
{
"id": "CXR1005_IM-0006",
"report": "Cardiac and mediastinal contours are within normal limits. The lungs are clear. Bony structures are intact.",
"image_path": [
"CXR1005_IM-0006/0.png",
"CXR1005_IM-0006/1.png"
],
"split": "test"
},
{
"id": "CXR3542_IM-1734",
"report": "Heart size and mediastinal contours appear within normal limits. Pulmonary vascularity is within normal limits. No focal consolidation, suspicious pulmonary opacity, pneumothorax or definite pleural effusion. Visualized osseous structures appear intact.",
"image_path": [
"CXR3542_IM-1734/0.png",
"CXR3542_IM-1734/1.png"
],
"split": "test"
},
{
"id": "CXR325_IM-1539",
"report": "Lungs are clear. No pleural effusions or pneumothoraces. Heart and mediastinum of normal size and contour.",
"image_path": [
"CXR325_IM-1539/0.png",
"CXR325_IM-1539/1.png"
],
"split": "test"
},
{
"id": "CXR2785_IM-1220",
"report": "Cardiac and mediastinal contours are within normal limits. The lungs are clear. Bony structures are intact.",
"image_path": [
"CXR2785_IM-1220/0.png",
"CXR2785_IM-1220/1.png"
],
"split": "test"
},
{
"id": "CXR3991_IM-2044",
"report": "The cardiac contours are normal. The lungs are clear. Thoracic spondylosis.",
"image_path": [
"CXR3991_IM-2044/0.png",
"CXR3991_IM-2044/1.png"
],
"split": "test"
},
{
"id": "CXR3527_IM-1724",
"report": "Both lungs are clear and expanded. Heart and mediastinum normal.",
"image_path": [
"CXR3527_IM-1724/0.png",
"CXR3527_IM-1724/1.png"
],
"split": "test"
},
{
"id": "CXR3460_IM-1681",
"report": "The heart and mediastinum are unremarkable. The lungs are clear without infiltrate. There is no effusion or pneumothorax.",
"image_path": [
"CXR3460_IM-1681/0.png",
"CXR3460_IM-1681/1.png"
],
"split": "test"
},
{
"id": "CXR2784_IM-1220",
"report": "The heart is normal in size and contour. There is no mediastinal widening. The lungs are clear bilaterally. No large pleural effusion or pneumothorax. The XXXX are intact.",
"image_path": [
"CXR2784_IM-1220/0.png",
"CXR2784_IM-1220/1.png"
],
"split": "test"
},
{
"id": "CXR1425_IM-0272",
"report": "The lungs are clear bilaterally. Specifically, no evidence of focal consolidation, pneumothorax, or pleural effusion.. Cardio mediastinal silhouette is unremarkable. Visualized osseous structures of the thorax are without acute abnormality.",
"image_path": [
"CXR1425_IM-0272/0.png",
"CXR1425_IM-0272/1.png"
],
"split": "test"
},
{
"id": "CXR779_IM-2321",
"report": "The cardiomediastinal silhouette is normal in size and contour. No focal consolidation, pneumothorax or large pleural effusion. Negative for acute displaced rib fracture.",
"image_path": [
"CXR779_IM-2321/0.png",
"CXR779_IM-2321/1.png"
],
"split": "test"
},
{
"id": "CXR1966_IM-0629",
"report": "The heart is normal in size. The mediastinum is unremarkable. The lungs are clear.",
"image_path": [
"CXR1966_IM-0629/0.png",
"CXR1966_IM-0629/1.png"
],
"split": "test"
},
{
"id": "CXR3765_IM-1884",
"report": "The cardiomediastinal silhouette is within normal limits for size and contour. The lungs are normally inflated without evidence of focal airspace disease, pleural effusion, or pneumothorax. Osseous structures are within normal limits for patient age..",
"image_path": [
"CXR3765_IM-1884/0.png",
"CXR3765_IM-1884/1.png"
],
"split": "test"
},
{
"id": "CXR2686_IM-1158",
"report": "Heart size within normal limits. No focal airspace disease. No pneumothorax or effusions.",
"image_path": [
"CXR2686_IM-1158/0.png",
"CXR2686_IM-1158/1.png"
],
"split": "test"
},
{
"id": "CXR2354_IM-0918",
"report": "Lungs are clear. No pneumothorax or pleural effusion. Normal heart and mediastinal contours. Normal pulmonary vasculature. Bony thorax intact.",
"image_path": [
"CXR2354_IM-0918/0.png",
"CXR2354_IM-0918/1.png"
],
"split": "test"
},
{
"id": "CXR3445_IM-1668",
"report": "No gross consolidation, atelectasis or infiltrate. No pleural fluid collection or pneumothorax. Cardiomediastinal silhouette is within normal limits. XXXX XXXX is intact.",
"image_path": [
"CXR3445_IM-1668/0.png",
"CXR3445_IM-1668/1.png"
],
"split": "test"
},
{
"id": "CXR3751_IM-1875",
"report": "The lungs are clear without evidence of focal airspace disease. There is no evidence of pneumothorax or large pleural effusion. The cardiac and mediastinal contours are within normal limits. The XXXX are unremarkable.",
"image_path": [
"CXR3751_IM-1875/0.png",
"CXR3751_IM-1875/1.png"
],
"split": "test"
},
{
"id": "CXR3734_IM-1866",
"report": "Lungs are clear bilaterally. Cardiac and mediastinal silhouettes are normal. Pulmonary vasculature is normal. No pneumothorax or pleural effusion. No acute bony abnormality.",
"image_path": [
"CXR3734_IM-1866/0.png",
"CXR3734_IM-1866/1.png"
],
"split": "test"
},
{
"id": "CXR377_IM-1889",
"report": "Heart size and pulmonary vascularity appear within normal limits. The lungs are free of focal airspace disease. No pleural effusion or pneumothorax is seen. Degenerative changes are present in the spine.",
"image_path": [
"CXR377_IM-1889/0.png",
"CXR377_IM-1889/1.png"
],
"split": "test"
},
{
"id": "CXR344_IM-1664",
"report": "The lungs are clear bilaterally. Specifically, no evidence of focal consolidation, pneumothorax, or pleural effusion.. Cardio mediastinal silhouette is unremarkable. Visualized osseous structures of the thorax are without acute abnormality.",
"image_path": [
"CXR344_IM-1664/0.png",
"CXR344_IM-1664/1.png"
],
"split": "test"
},
{
"id": "CXR3646_IM-1808-0001",
"report": "The lungs are clear. Heart size is normal. No pneumothorax.",
"image_path": [
"CXR3646_IM-1808-0001/0.png",
"CXR3646_IM-1808-0001/1.png"
],
"split": "test"
},
{
"id": "CXR3335_IM-1598",
"report": "Heart size and mediastinal contour are normal. Pulmonary vascularity is normal. Lungs are clear. No pleural effusions or pneumothoraces. Degenerative changes in the thoracic spine.",
"image_path": [
"CXR3335_IM-1598/0.png",
"CXR3335_IM-1598/1.png"
],
"split": "test"
},
{
"id": "CXR2780_IM-1218",
"report": "The heart and lungs have XXXX XXXX in the interval. Both lungs are clear and expanded. Heart and mediastinum normal.",
"image_path": [
"CXR2780_IM-1218/0.png",
"CXR2780_IM-1218/1.png"
],
"split": "test"
},
{
"id": "CXR1997_IM-0651",
"report": "Heart size normal. Lungs are clear. XXXX are normal. No pneumonia, effusions, edema, pneumothorax, adenopathy, nodules or masses.",
"image_path": [
"CXR1997_IM-0651/0.png",
"CXR1997_IM-0651/1.png"
],
"split": "test"
},
{
"id": "CXR1440_IM-0284",
"report": "Cardiac and mediastinal contours are within normal limits. The lungs are clear. Bony structures are intact.",
"image_path": [
"CXR1440_IM-0284/0.png",
"CXR1440_IM-0284/1.png"
],
"split": "test"
},
{
"id": "CXR1259_IM-0175",
"report": "The heart is normal in size. The mediastinum is unremarkable. The lungs are clear.",
"image_path": [
"CXR1259_IM-0175/0.png",
"CXR1259_IM-0175/1.png"
],
"split": "test"
},
{
"id": "CXR658_IM-2234",
"report": "The lungs are clear. The heart and pulmonary XXXX are normal. The pleural spaces are clear. Mediastinal contours are normal.",
"image_path": [
"CXR658_IM-2234/0.png",
"CXR658_IM-2234/1.png"
],
"split": "test"
},
{
"id": "CXR1812_IM-0525",
"report": "No focal consolidation, suspicious pulmonary opacity, pneumothorax or definite pleural effusion. Heart size and pulmonary vascularity within normal limits, visualized osseous structures appear intact.",
"image_path": [
"CXR1812_IM-0525/0.png",
"CXR1812_IM-0525/1.png"
],
"split": "test"
},
{
"id": "CXR2357_IM-0921",
"report": "Cardiomediastinal silhouette and pulmonary vasculature are within normal limits. Lungs are clear. No pneumothorax or pleural effusion. No acute osseous findings.",
"image_path": [
"CXR2357_IM-0921/0.png",
"CXR2357_IM-0921/1.png"
],
"split": "test"
},
{
"id": "CXR2232_IM-0832",
"report": "The lungs are clear bilaterally. Specifically, no evidence of focal consolidation, pneumothorax, or pleural effusion. Cardiomediastinal silhouette is unremarkable. Visualized osseous structures of the thorax are without acute abnormality.",
"image_path": [
"CXR2232_IM-0832/0.png",
"CXR2232_IM-0832/1.png"
],
"split": "test"
},
{
"id": "CXR993_IM-2478",
"report": "Heart size normal. Lungs are clear. XXXX are normal. No pneumonia, effusions, edema, pneumothorax, adenopathy, nodules or masses.",
"image_path": [
"CXR993_IM-2478/0.png",
"CXR993_IM-2478/1.png"
],
"split": "test"
},
{
"id": "CXR2734_IM-1189",
"report": "The cardiomediastinal silhouette is within normal limits for size and contour. The lungs are normally inflated without evidence of focal airspace disease, pleural effusion, or pneumothorax. Osseous structures are within normal limits for patient age..",
"image_path": [
"CXR2734_IM-1189/0.png",
"CXR2734_IM-1189/1.png"
],
"split": "test"
},
{
"id": "CXR461_IM-2090",
"report": "The cardiomediastinal silhouette is normal size and configuration. Pulmonary vasculature within normal limits. The lungs are well-aerated. There is no pneumothorax, pleural effusion, or focal consolidation.",
"image_path": [
"CXR461_IM-2090/0.png",
"CXR461_IM-2090/1.png"
],
"split": "test"
},
{
"id": "CXR2098_IM-0728",
"report": "The heart size is normal. Lungs are clear. There is no pleural line to suggest pneumothorax or costophrenic XXXX blunting to suggest large pleural effusion. Bony structures are within normal limits.",
"image_path": [
"CXR2098_IM-0728/0.png",
"CXR2098_IM-0728/1.png"
],
"split": "test"
},
{
"id": "CXR2277_IM-0864",
"report": "The lungs are clear without evidence of focal airspace disease. There is no evidence of pneumothorax or large pleural effusion. The cardiac and mediastinal contours are within normal limits. The XXXX are unremarkable.",
"image_path": [
"CXR2277_IM-0864/0.png",
"CXR2277_IM-0864/1.png"
],
"split": "test"
},
{
"id": "CXR2099_IM-0729",
"report": "The lungs are clear bilaterally. Specifically, no evidence of focal consolidation, pneumothorax, or pleural effusion.. Cardio mediastinal silhouette is unremarkable. Visualized osseous structures of the thorax are without acute abnormality.",
"image_path": [
"CXR2099_IM-0729/0.png",
"CXR2099_IM-0729/1.png"
],
"split": "test"
},
{
"id": "CXR1633_IM-0414",
"report": "The lungs are clear bilaterally. Specifically, no evidence of focal consolidation, pneumothorax, or pleural effusion.. Cardio mediastinal silhouette is unremarkable. Visualized osseous structures of the thorax are without acute abnormality.",
"image_path": [
"CXR1633_IM-0414/0.png",
"CXR1633_IM-0414/1.png"
],
"split": "test"
},
{
"id": "CXR3883_IM-1971",
"report": "No pneumothorax, pleural effusion or airspace consolidation. Heart size and pulmonary vasculature appear within normal limits. XXXX XXXX are intact.",
"image_path": [
"CXR3883_IM-1971/0.png",
"CXR3883_IM-1971/1.png"
],
"split": "test"
},
{
"id": "CXR3041_IM-1415",
"report": "Heart size normal. Lungs are clear. XXXX are normal. No pneumonia, effusions, edema, pneumothorax, adenopathy, nodules or masses.",
"image_path": [
"CXR3041_IM-1415/0.png",
"CXR3041_IM-1415/1.png"
],
"split": "test"
},
{
"id": "CXR269_IM-1161",
"report": "The cardiomediastinal silhouette is normal size and configuration. Pulmonary vasculature within normal limits. The lungs are well-aerated. There is no pneumothorax, pleural effusion, or focal consolidation.",
"image_path": [
"CXR269_IM-1161/0.png",
"CXR269_IM-1161/1.png"
],
"split": "test"
},
{
"id": "CXR3552_IM-1741",
"report": "Heart size within normal limits, stable mediastinal and hilar contours. No focal alveolar consolidation, no definite pleural effusion seen. No typical findings of pulmonary edema.",
"image_path": [
"CXR3552_IM-1741/0.png",
"CXR3552_IM-1741/1.png"
],
"split": "test"
},
{
"id": "CXR1854_IM-0555",
"report": "The cardiomediastinal silhouette is normal in size and contour. No focal consolidation, pneumothorax or large pleural effusion. Negative for acute displaced rib fracture.",
"image_path": [
"CXR1854_IM-0555/0.png",
"CXR1854_IM-0555/1.png"
],
"split": "test"
},
{
"id": "CXR3745_IM-1872",
"report": "Cardiomediastinal silhouette and pulmonary vasculature are within normal limits. Lungs are clear. No pneumothorax or pleural effusion. No acute osseous findings.",
"image_path": [
"CXR3745_IM-1872/0.png",
"CXR3745_IM-1872/1.png"
],
"split": "test"
},
{
"id": "CXR1467_IM-0302",
"report": "The lungs are clear bilaterally. Specifically, no evidence of focal consolidation, pneumothorax, or pleural effusion. Cardiomediastinal silhouette is unremarkable. Visualized osseous structures of the thorax are without acute abnormality.",
"image_path": [
"CXR1467_IM-0302/0.png",
"CXR1467_IM-0302/1.png"
],
"split": "test"
},
{
"id": "CXR1270_IM-0181",
"report": "2 images. Heart size and pulmonary vascular engorgement appear within limits of normal. Mediastinal contour is unremarkable. No focal consolidation, pleural effusion, or pneumothorax identified. No convincing acute bony findings.",
"image_path": [
"CXR1270_IM-0181/0.png",
"CXR1270_IM-0181/1.png"
],
"split": "test"
},
{
"id": "CXR3098_IM-1450",
"report": "Heart size and mediastinal contours appear within normal limits. Pulmonary vascularity is within normal limits. No focal consolidation, suspicious pulmonary opacity, pneumothorax or definite pleural effusion. Visualized osseous structures appear intact.",
"image_path": [
"CXR3098_IM-1450/0.png",
"CXR3098_IM-1450/1.png"
],
"split": "test"
},
{
"id": "CXR1603_IM-0391",
"report": "Heart size normal. Lungs are clear. XXXX are normal. No pneumonia, effusions, edema, pneumothorax, adenopathy, nodules or masses.",
"image_path": [
"CXR1603_IM-0391/0.png",
"CXR1603_IM-0391/1.png"
],
"split": "test"
},
{
"id": "CXR1008_IM-0009",
"report": "Heart size and mediastinal contours are normal in appearance. No consolidative airspace opacities. No radiographic evidence of pleural effusion or pneumothorax. Visualized osseous structures appear intact.",
"image_path": [
"CXR1008_IM-0009/0.png",
"CXR1008_IM-0009/1.png"
],
"split": "test"
},
{
"id": "CXR2916_IM-1318",
"report": "Heart size within normal limits. No focal alveolar consolidation, no definite pleural effusion seen. No typical findings of pulmonary edema. No pneumothorax.",
"image_path": [
"CXR2916_IM-1318/0.png",
"CXR2916_IM-1318/1.png"
],
"split": "test"
},
{
"id": "CXR1632_IM-0413",
"report": "The lungs are clear bilaterally. Specifically, no evidence of focal consolidation, pneumothorax, or pleural effusion.. Cardio mediastinal silhouette is unremarkable. Visualized osseous structures of the thorax are without acute abnormality.",
"image_path": [
"CXR1632_IM-0413/0.png",
"CXR1632_IM-0413/1.png"
],
"split": "test"
},
{
"id": "CXR3265_IM-1551",
"report": "The heart size and mediastinal contours appear within normal limits. No focal airspace consolidation, pleural effusion or pneumothorax. No acute bony abnormalities.",
"image_path": [
"CXR3265_IM-1551/0.png",
"CXR3265_IM-1551/1.png"
],
"split": "test"
},
{
"id": "CXR2851_IM-1260-0001",
"report": "The cardiomediastinal silhouette and pulmonary vasculature are within normal limits in size. The lungs are clear of focal airspace disease, pneumothorax, or pleural effusion. There are no acute bony findings.",
"image_path": [
"CXR2851_IM-1260-0001/0.png",
"CXR2851_IM-1260-0001/1.png"
],
"split": "test"
},
{
"id": "CXR242_IM-0963",
"report": "Lungs are clear bilaterally with no focal infiltrate, pleural effusion, or pneumothoraces. Cardiomediastinal silhouette is within normal limits. XXXX and soft tissues are unremarkable.",
"image_path": [
"CXR242_IM-0963/0.png",
"CXR242_IM-0963/1.png"
],
"split": "test"
},
{
"id": "CXR3427_IM-1657",
"report": "The cardiac silhouette and mediastinum size are within normal limits. There is no pulmonary edema. There is no focal consolidation. There are no XXXX of a large pleural effusion. There is no evidence of pneumothorax.",
"image_path": [
"CXR3427_IM-1657/0.png",
"CXR3427_IM-1657/1.png"
],
"split": "test"
},
{
"id": "CXR3220_IM-1522",
"report": "Lungs are clear. There is no pneumothorax or pleural effusion. The heart and mediastinum are within normal limits. Bony structures are intact.",
"image_path": [
"CXR3220_IM-1522/0.png",
"CXR3220_IM-1522/1.png"
],
"split": "test"
},
{
"id": "CXR2005_IM-0656",
"report": "Heart size normal. Lungs are clear. XXXX are normal. No pneumonia, effusions, edema, pneumothorax, adenopathy, nodules or masses.",
"image_path": [
"CXR2005_IM-0656/0.png",
"CXR2005_IM-0656/1.png"
],
"split": "test"
},
{
"id": "CXR1410_IM-0260",
"report": "The heart size is normal. The mediastinal contour is within normal limits. The lungs are free of any focal infiltrates. There are no nodules or masses. No visible pneumothorax. No visible pleural fluid. The XXXX are grossly normal. There is no visible free intraperitoneal air under the diaphragm.",
"image_path": [
"CXR1410_IM-0260/0.png",
"CXR1410_IM-0260/1.png"
],
"split": "test"
},
{
"id": "CXR879_IM-2393",
"report": "Cardiac and mediastinal contours are within normal limits. The lungs are clear. Bony structures are intact.",
"image_path": [
"CXR879_IM-2393/0.png",
"CXR879_IM-2393/1.png"
],
"split": "test"
},
{
"id": "CXR3020_IM-1395",
"report": "Heart size and mediastinal contours are normal in appearance. No consolidative airspace opacities. No radiographic evidence of pleural effusion or pneumothorax. Visualized osseous structures appear intact.",
"image_path": [
"CXR3020_IM-1395/0.png",
"CXR3020_IM-1395/1.png"
],
"split": "test"
},
{
"id": "CXR632_IM-2213",
"report": "Cardiac and mediastinal silhouette are unremarkable. Lungs are clear. No focal consolidation, pneumothorax, or pleural effusion identified. XXXX and soft tissue are unremarkable.",
"image_path": [
"CXR632_IM-2213/0.png",
"CXR632_IM-2213/1.png"
],
"split": "test"
},
{
"id": "CXR2937_IM-1339",
"report": "The heart size and mediastinal contours appear within normal limits. No focal airspace consolidation, pleural effusion or pneumothorax. No acute bony abnormalities.",
"image_path": [
"CXR2937_IM-1339/0.png",
"CXR2937_IM-1339/1.png"
],
"split": "test"
},
{
"id": "CXR328_IM-1560",
"report": "The heart size and pulmonary vascularity appear within normal limits. The lungs are free of focal airspace disease. No pleural effusion or pneumothorax is seen.",
"image_path": [
"CXR328_IM-1560/0.png",
"CXR328_IM-1560/1.png"
],
"split": "test"
},
{
"id": "CXR3817_IM-1925",
"report": "Lungs are clear bilaterally with no focal infiltrate, pleural effusion, or pneumothoraces. Cardiomediastinal silhouette is within normal limits. XXXX and soft tissues are unremarkable.",
"image_path": [
"CXR3817_IM-1925/0.png",
"CXR3817_IM-1925/1.png"
],
"split": "test"
},
{
"id": "CXR3059_IM-1425",
"report": "Lungs are clear bilaterally. There is no focal consolidation, pleural effusion, or pneumothoraces. Cardiomediastinal silhouette is within normal limits. XXXX are unremarkable.",
"image_path": [
"CXR3059_IM-1425/0.png",
"CXR3059_IM-1425/1.png"
],
"split": "test"
},
{
"id": "CXR2389_IM-0944",
"report": "2 images. Heart size and pulmonary vascular engorgement appear within limits of normal. Mediastinal contour is unremarkable. No focal consolidation, pleural effusion, or pneumothorax identified. No convincing acute bony findings.",
"image_path": [
"CXR2389_IM-0944/0.png",
"CXR2389_IM-0944/1.png"
],
"split": "test"
},
{
"id": "CXR869_IM-2389",
"report": "The heart is normal size. The mediastinum is unremarkable. There is no pleural effusion, pneumothorax, or focal airspace disease. The XXXX are unremarkable.",
"image_path": [
"CXR869_IM-2389/0.png",
"CXR869_IM-2389/1.png"
],
"split": "test"
},
{
"id": "CXR751_IM-2305",
"report": "Heart size within normal limits. No focal alveolar consolidation, no definite pleural effusion seen. No typical findings of pulmonary edema. No pneumothorax.",
"image_path": [
"CXR751_IM-2305/0.png",
"CXR751_IM-2305/1.png"
],
"split": "test"
},
{
"id": "CXR1209_IM-0142",
"report": "The lungs are clear bilaterally. Specifically, no evidence of focal consolidation, pneumothorax, or pleural effusion.. Cardio mediastinal silhouette is unremarkable. Visualized osseous structures of the thorax are without acute abnormality.",
"image_path": [
"CXR1209_IM-0142/0.png",
"CXR1209_IM-0142/1.png"
],
"split": "test"
},
{
"id": "CXR1588_IM-0382",
"report": "Heart size normal. Lungs are clear. XXXX are normal. No pneumonia, effusions, edema, pneumothorax, adenopathy, nodules or masses.",
"image_path": [
"CXR1588_IM-0382/0.png",
"CXR1588_IM-0382/1.png"
],
"split": "test"
},
{
"id": "CXR487_IM-2110",
"report": "Cardiomediastinal silhouettes are within normal limits. Lungs are clear without focal consolidation, pneumothorax, or pleural effusion. Bony thorax is unremarkable.",
"image_path": [
"CXR487_IM-2110/0.png",
"CXR487_IM-2110/1.png"
],
"split": "test"
},
{
"id": "CXR2940_IM-1341",
"report": "Heart size and mediastinal contour are normal. Pulmonary vascularity is normal. Lungs are clear. No pleural effusions or pneumothoraces. Degenerative changes in the thoracic spine.",
"image_path": [
"CXR2940_IM-1341/0.png",
"CXR2940_IM-1341/1.png"
],
"split": "test"
},
{
"id": "CXR1831_IM-0538",
"report": "Heart size within normal limits. No focal alveolar consolidation, no definite pleural effusion seen. No typical findings of pulmonary edema. No pneumothorax.",
"image_path": [
"CXR1831_IM-0538/0.png",
"CXR1831_IM-0538/1.png"
],
"split": "test"
},
{
"id": "CXR717_IM-2279",
"report": "The heart is normal in size. The mediastinum is unremarkable. The lungs are clear.",
"image_path": [
"CXR717_IM-2279/0.png",
"CXR717_IM-2279/1.png"
],
"split": "test"
},
{
"id": "CXR1434_IM-0279",
"report": "Both lungs are clear and expanded. Heart and mediastinum normal.",
"image_path": [
"CXR1434_IM-0279/0.png",
"CXR1434_IM-0279/1.png"
],
"split": "test"
},
{
"id": "CXR931_IM-2429",
"report": "The lungs and pleural spaces show no acute abnormality. Heart size and pulmonary vascularity within normal limits.",
"image_path": [
"CXR931_IM-2429/0.png",
"CXR931_IM-2429/1.png"
],
"split": "test"
},
{
"id": "CXR735_IM-2294",
"report": "The cardiomediastinal silhouette is within normal limits for size and contour. The lungs are normally inflated without evidence of focal airspace disease, pleural effusion, or pneumothorax. No acute osseus abnormality.",
"image_path": [
"CXR735_IM-2294/0.png",
"CXR735_IM-2294/1.png"
],
"split": "test"
},
{
"id": "CXR870_IM-2391",
"report": "The heart and lungs have XXXX XXXX in the interval. Both lungs are clear and expanded. Heart and mediastinum normal.",
"image_path": [
"CXR870_IM-2391/0.png",
"CXR870_IM-2391/1.png"
],
"split": "test"
},
{
"id": "CXR588_IM-2183",
"report": "The heart is normal in size and contour. There is no mediastinal widening. The lungs are clear bilaterally. No large pleural effusion or pneumothorax. The XXXX are intact.",
"image_path": [
"CXR588_IM-2183/0.png",
"CXR588_IM-2183/1.png"
],
"split": "test"
},
{
"id": "CXR1509_IM-0331",
"report": "Lungs are clear bilaterally.There is no focal consolidation, pleural effusion, or pneumothoraces. Cardiomediastinal silhouette is within normal limits. XXXX are unremarkable.",
"image_path": [
"CXR1509_IM-0331/0.png",
"CXR1509_IM-0331/1.png"
],
"split": "test"
},
{
"id": "CXR2953_IM-1351",
"report": "The lungs are clear. There is no pleural effusion or pneumothorax. The heart and mediastinum are normal. The skeletal structures are normal.",
"image_path": [
"CXR2953_IM-1351/0.png",
"CXR2953_IM-1351/1.png"
],
"split": "test"
},
{
"id": "CXR2204_IM-0813",
"report": "The heart and lungs have XXXX XXXX in the interval. Both lungs are clear and expanded. Heart and mediastinum normal.",
"image_path": [
"CXR2204_IM-0813/0.png",
"CXR2204_IM-0813/1.png"
],
"split": "test"
},
{
"id": "CXR43_IM-2070",
"report": "The heart and lungs have XXXX XXXX in the interval. Both lungs are clear and expanded. Heart and mediastinum normal.",
"image_path": [
"CXR43_IM-2070/0.png",
"CXR43_IM-2070/1.png"
],
"split": "test"
},
{
"id": "CXR3446_IM-1669",
"report": "Cardiac and mediastinal contours are within normal limits. The lungs are clear. Bony structures are intact.",
"image_path": [
"CXR3446_IM-1669/0.png",
"CXR3446_IM-1669/1.png"
],
"split": "test"
},
{
"id": "CXR3495_IM-1700",
"report": "The cardiomediastinal silhouette is within normal limits for size and contour. The lungs are normally inflated without evidence of focal airspace disease, pleural effusion, or pneumothorax. Osseous structures are within normal limits for patient age..",
"image_path": [
"CXR3495_IM-1700/0.png",
"CXR3495_IM-1700/1.png"
],
"split": "test"
},
{
"id": "CXR795_IM-2331",
"report": "Heart size normal. Lungs are clear. XXXX are normal. No pneumonia, effusions, edema, pneumothorax, adenopathy, nodules or masses.",
"image_path": [
"CXR795_IM-2331/0.png",
"CXR795_IM-2331/1.png"
],
"split": "test"
},
{
"id": "CXR3867_IM-1960",
"report": "The cardiomediastinal silhouette and pulmonary vasculature are within normal limits in size. The lungs are clear of focal airspace disease, pneumothorax, or pleural effusion. There are no acute bony findings.",
"image_path": [
"CXR3867_IM-1960/0.png",
"CXR3867_IM-1960/1.png"
],
"split": "test"
},
{
"id": "CXR3720_IM-1859",
"report": "The cardiomediastinal silhouette and pulmonary vasculature are within normal limits in size. The lungs are clear of focal airspace disease, pneumothorax, or pleural effusion. There are no acute bony findings.",
"image_path": [
"CXR3720_IM-1859/0.png",
"CXR3720_IM-1859/1.png"
],
"split": "test"
},
{
"id": "CXR1931_IM-0602",
"report": "The heart is normal in size. The mediastinum is unremarkable. The lungs are clear.",
"image_path": [
"CXR1931_IM-0602/0.png",
"CXR1931_IM-0602/1.png"
],
"split": "test"
},
{
"id": "CXR1771_IM-0505",
"report": "The heart and lungs have XXXX XXXX in the interval. Both lungs are clear and expanded. Heart and mediastinum normal.",
"image_path": [
"CXR1771_IM-0505/0.png",
"CXR1771_IM-0505/1.png"
],
"split": "test"
},
{
"id": "CXR3126_IM-1470",
"report": "The cardiomediastinal silhouette is within normal limits for appearance. No focal areas of pulmonary consolidation. No pneumothorax. No pleural effusion. The thoracic spine appears intact. No acute, displaced rib fractures.",
"image_path": [
"CXR3126_IM-1470/0.png",
"CXR3126_IM-1470/1.png"
],
"split": "test"
},
{
"id": "CXR3105_IM-1456",
"report": "Heart and mediastinum within normal limits. Negative for focal pulmonary consolidation, pleural effusion, or pneumothorax.",
"image_path": [
"CXR3105_IM-1456/0.png",
"CXR3105_IM-1456/1.png"
],
"split": "test"
},
{
"id": "CXR2796_IM-1228",
"report": "Cardiac and mediastinal contours are within normal limits. The lungs are clear. Bony structures are intact.",
"image_path": [
"CXR2796_IM-1228/0.png",
"CXR2796_IM-1228/1.png"
],
"split": "test"
},
{
"id": "CXR1323_IM-0209",
"report": "The heart size and mediastinal silhouette are within normal limits for contour. The lungs are clear. No pneumothorax or pleural effusions. The XXXX are intact.",
"image_path": [
"CXR1323_IM-0209/0.png",
"CXR1323_IM-0209/1.png"
],
"split": "test"
},
{
"id": "CXR1309_IM-0201-1001",
"report": "The cardiomediastinal silhouette and pulmonary vasculature are within normal limits in size. The lungs are clear of focal airspace disease, pneumothorax, or pleural effusion. There are no acute bony findings.",
"image_path": [
"CXR1309_IM-0201-1001/0.png",
"CXR1309_IM-0201-1001/1.png"
],
"split": "test"
},
{
"id": "CXR2423_IM-0965",
"report": "The heart is normal in size. The mediastinum is unremarkable. The lungs are clear.",
"image_path": [
"CXR2423_IM-0965/0.png",
"CXR2423_IM-0965/1.png"
],
"split": "test"
},
{
"id": "CXR3194_IM-1505",
"report": "The heart size and mediastinal silhouette are within normal limits for contour. The lungs are clear. No pneumothorax or pleural effusions. The XXXX are intact.",
"image_path": [
"CXR3194_IM-1505/0.png",
"CXR3194_IM-1505/1.png"
],
"split": "test"
},
{
"id": "CXR2136_IM-0758",
"report": "Mediastinal contours are normal. Lungs are clear. There is no pneumothorax or large pleural effusion.",
"image_path": [
"CXR2136_IM-0758/0.png",
"CXR2136_IM-0758/1.png"
],
"split": "test"
},
{
"id": "CXR3778_IM-1894",
"report": "Cardiac and mediastinal contours are within normal limits. The lungs are clear. Bony structures are intact.",
"image_path": [
"CXR3778_IM-1894/0.png",
"CXR3778_IM-1894/1.png"
],
"split": "test"
},
{
"id": "CXR1726_IM-0479",
"report": "Both lungs are clear and expanded. Heart and mediastinum normal.",
"image_path": [
"CXR1726_IM-0479/0.png",
"CXR1726_IM-0479/1.png"
],
"split": "test"
},
{
"id": "CXR2889_IM-1291",
"report": "The cardiomediastinal silhouette is within normal limits for size and contour. The lungs are normally inflated without evidence of focal airspace disease, pleural effusion, or pneumothorax. Osseous structures are within normal limits for patient age..",
"image_path": [
"CXR2889_IM-1291/0.png",
"CXR2889_IM-1291/1.png"
],
"split": "test"
},
{
"id": "CXR2786_IM-1221",
"report": "The lungs are clear bilaterally. Specifically, no evidence of focal consolidation, pneumothorax, or pleural effusion.. Cardio mediastinal silhouette is unremarkable. Visualized osseous structures of the thorax are without acute abnormality.",
"image_path": [
"CXR2786_IM-1221/0.png",
"CXR2786_IM-1221/1.png"
],
"split": "test"
},
{
"id": "CXR497_IM-2114",
"report": "Heart size normal. Lungs are clear. XXXX are normal. No pneumonia, effusions, edema, pneumothorax, adenopathy, nodules or masses.",
"image_path": [
"CXR497_IM-2114/0.png",
"CXR497_IM-2114/1.png"
],
"split": "test"
},
{
"id": "CXR162_IM-0401",
"report": "Heart size normal. Lungs are clear. XXXX are normal. No pneumonia, effusions, edema, pneumothorax, adenopathy, nodules or masses.",
"image_path": [
"CXR162_IM-0401/0.png",
"CXR162_IM-0401/1.png"
],
"split": "test"
},
{
"id": "CXR3763_IM-1883",
"report": "Both lungs are clear and expanded. Heart and mediastinum normal.",
"image_path": [
"CXR3763_IM-1883/0.png",
"CXR3763_IM-1883/1.png"
],
"split": "test"
},
{
"id": "CXR485_IM-2109",
"report": "The heart and lungs have XXXX XXXX in the interval. Both lungs are clear and expanded. Heart and mediastinum normal.",
"image_path": [
"CXR485_IM-2109/0.png",
"CXR485_IM-2109/1.png"
],
"split": "test"
},
{
"id": "CXR2020_IM-0668",
"report": "No focal lung consolidation. Heart size and pulmonary vascularity are within normal limits. No pneumothorax or pleural effusion. Osseous structures are grossly intact.",
"image_path": [
"CXR2020_IM-0668/0.png",
"CXR2020_IM-0668/1.png"
],
"split": "test"
},
{
"id": "CXR2623_IM-1111",
"report": "Lungs are clear bilaterally with no focal infiltrate, pleural effusion, or pneumothoraces. Cardiomediastinal silhouette is within normal limits. No acute bony or soft tissue abnormality.",
"image_path": [
"CXR2623_IM-1111/0.png",
"CXR2623_IM-1111/1.png"
],
"split": "test"
},
{
"id": "CXR1190_IM-0128",
"report": "Both lungs are clear and expanded. Heart and mediastinum normal.",
"image_path": [
"CXR1190_IM-0128/0.png",
"CXR1190_IM-0128/1.png"
],
"split": "test"
},
{
"id": "CXR1646_IM-0423",
"report": "The lungs are clear bilaterally. Specifically, no evidence of focal consolidation, pneumothorax, or pleural effusion.. Cardio mediastinal silhouette is unremarkable. Visualized osseous structures of the thorax are without acute abnormality.",
"image_path": [
"CXR1646_IM-0423/0.png",
"CXR1646_IM-0423/1.png"
],
"split": "test"
},
{
"id": "CXR1373_IM-0240",
"report": "The lungs are clear. There is no pleural effusion or pneumothorax. The heart is not significantly enlarged. There are atherosclerotic changes of the aorta. Arthritic changes of the skeletal structures are noted.",
"image_path": [
"CXR1373_IM-0240/0.png",
"CXR1373_IM-0240/1.png"
],
"split": "test"
},
{
"id": "CXR1627_IM-0408",
"report": "The lungs and pleural spaces show no acute abnormality. Heart size and pulmonary vascularity within normal limits. .",
"image_path": [
"CXR1627_IM-0408/0.png",
"CXR1627_IM-0408/1.png"
],
"split": "test"
},
{
"id": "CXR2592_IM-1084",
"report": "The lungs are clear. There is no pleural effusion or pneumothorax. The heart and mediastinum are normal. The skeletal structures are normal.",
"image_path": [
"CXR2592_IM-1084/0.png",
"CXR2592_IM-1084/1.png"
],
"split": "test"
},
{
"id": "CXR364_IM-1804",
"report": "The cardiomediastinal silhouette and pulmonary vasculature are within normal limits in size. The lungs are clear of focal airspace disease, pneumothorax, or pleural effusion. There are no acute bony findings.",
"image_path": [
"CXR364_IM-1804/0.png",
"CXR364_IM-1804/1.png"
],
"split": "test"
},
{
"id": "CXR3890_IM-1973",
"report": "Lungs are clear bilaterally with no focal infiltrate, pleural effusion, or pneumothoraces. Cardiomediastinal silhouette is within normal limits. XXXX and soft tissues are unremarkable.",
"image_path": [
"CXR3890_IM-1973/0.png",
"CXR3890_IM-1973/1.png"
],
"split": "test"
},
{
"id": "CXR1956_IM-0623",
"report": "The cardiomediastinal contours are within normal limits. Pulmonary vasculature is unremarkable. There is no focal airspace opacity. No pleural effusion or pneumothorax is seen. No acute bony abnormality is identified.",
"image_path": [
"CXR1956_IM-0623/0.png",
"CXR1956_IM-0623/1.png"
],
"split": "test"
},
{
"id": "CXR3902_IM-1981",
"report": "The heart and lungs have XXXX XXXX in the interval. Both lungs are clear and expanded. Heart and mediastinum normal.",
"image_path": [
"CXR3902_IM-1981/0.png",
"CXR3902_IM-1981/1.png"
],
"split": "test"
},
{
"id": "CXR1219_IM-0146",
"report": "Heart size and mediastinal contours are normal in appearance. No consolidative airspace opacities. No radiographic evidence of pleural effusion or pneumothorax. Visualized osseous structures appear intact.",
"image_path": [
"CXR1219_IM-0146/0.png",
"CXR1219_IM-0146/1.png"
],
"split": "test"
},
{
"id": "CXR932_IM-2430",
"report": "No gross consolidation, atelectasis or infiltrate. No pleural fluid collection or pneumothorax. Cardiomediastinal silhouette is within normal limits. XXXX XXXX is intact.",
"image_path": [
"CXR932_IM-2430/0.png",
"CXR932_IM-2430/1.png"
],
"split": "test"
},
{
"id": "CXR1487_IM-0314",
"report": "The heart and lungs have XXXX XXXX in the interval. Both lungs are clear and expanded. Heart and mediastinum normal.",
"image_path": [
"CXR1487_IM-0314/0.png",
"CXR1487_IM-0314/1.png"
],
"split": "test"
},
{
"id": "CXR1454_IM-0293",
"report": "The heart is normal in size. The mediastinum is unremarkable. The lungs are clear.",
"image_path": [
"CXR1454_IM-0293/0.png",
"CXR1454_IM-0293/1.png"
],
"split": "test"
},
{
"id": "CXR1582_IM-0378",
"report": "Both lungs are clear and expanded. Heart and mediastinum normal.",
"image_path": [
"CXR1582_IM-0378/0.png",
"CXR1582_IM-0378/1.png"
],
"split": "test"
},
{
"id": "CXR2413_IM-0959",
"report": "Heart size and pulmonary vascularity within normal limits. No focal infiltrate, pneumothorax or pleural effusion identified.",
"image_path": [
"CXR2413_IM-0959/0.png",
"CXR2413_IM-0959/1.png"
],
"split": "test"
},
{
"id": "CXR141_IM-0260",
"report": "Cardiac size, mediastinal contour, and pulmonary vascularity are within normal limits. No focal consolidation, suspicious pulmonary opacity, pleural effusion, or pneumothorax. The visualized osseous structures appear intact.",
"image_path": [
"CXR141_IM-0260/0.png",
"CXR141_IM-0260/1.png"
],
"split": "test"
},
{
"id": "CXR2910_IM-1314",
"report": "The heart size is normal. The mediastinal contour is within normal limits. The lungs are free of any focal infiltrates. There are no nodules or masses. No visible pneumothorax. No visible pleural fluid. The XXXX are grossly normal. There is no visible free intraperitoneal air under the diaphragm.",
"image_path": [
"CXR2910_IM-1314/0.png",
"CXR2910_IM-1314/1.png"
],
"split": "test"
},
{
"id": "CXR3549_IM-1739-1001",
"report": "The lungs are clear bilaterally. Specifically, no evidence of focal consolidation, pneumothorax, or pleural effusion.. Cardio mediastinal silhouette is unremarkable. Visualized osseous structures of the thorax are without acute abnormality.",
"image_path": [
"CXR3549_IM-1739-1001/0.png",
"CXR3549_IM-1739-1001/1.png"
],
"split": "test"
},
{
"id": "CXR3603_IM-1779",
"report": "Cardiac and mediastinal contours are within normal limits. The lungs are clear. Bony structures are intact.",
"image_path": [
"CXR3603_IM-1779/0.png",
"CXR3603_IM-1779/1.png"
],
"split": "test"
},
{
"id": "CXR1093_IM-0064",
"report": "The heart size and pulmonary vascularity appear within normal limits. The lungs are free of focal airspace disease. No pleural effusion or pneumothorax is seen.",
"image_path": [
"CXR1093_IM-0064/0.png",
"CXR1093_IM-0064/1.png"
],
"split": "test"
},
{
"id": "CXR2862_IM-1270",
"report": "The cardiomediastinal silhouette is within normal limits for size and contour. The lungs are normally inflated without evidence of focal airspace disease, pleural effusion, or pneumothorax. Osseous structures are within normal limits for patient age..",
"image_path": [
"CXR2862_IM-1270/0.png",
"CXR2862_IM-1270/1.png"
],
"split": "test"
},
{
"id": "CXR12_IM-0133",
"report": "Lungs are clear bilaterally. Cardiac and mediastinal silhouettes are normal. Pulmonary vasculature is normal. No pneumothorax or pleural effusion. No acute bony abnormality.",
"image_path": [
"CXR12_IM-0133/0.png",
"CXR12_IM-0133/1.png"
],
"split": "test"
},
{
"id": "CXR1535_IM-0346",
"report": "Heart size and mediastinal contours appear within normal limits. Pulmonary vascularity is within normal limits. No focal consolidation, suspicious pulmonary opacity, pneumothorax or definite pleural effusion. Visualized osseous structures appear intact.",
"image_path": [
"CXR1535_IM-0346/0.png",
"CXR1535_IM-0346/1.png"
],
"split": "test"
},
{
"id": "CXR3063_IM-1428",
"report": "Lungs are clear bilaterally. Cardiac and mediastinal silhouettes are normal. Pulmonary vasculature is normal. No pneumothorax or pleural effusion. No acute bony abnormality.",
"image_path": [
"CXR3063_IM-1428/0.png",
"CXR3063_IM-1428/1.png"
],
"split": "test"
},
{
"id": "CXR771_IM-2316",
"report": "Heart size and pulmonary vascularity within normal limits. No focal infiltrate, pneumothorax or pleural effusion identified.",
"image_path": [
"CXR771_IM-2316/0.png",
"CXR771_IM-2316/1.png"
],
"split": "test"
},
{
"id": "CXR3532_IM-1726",
"report": "The heart and lungs have XXXX XXXX in the interval. Both lungs are clear and expanded. Heart and mediastinum normal.",
"image_path": [
"CXR3532_IM-1726/0.png",
"CXR3532_IM-1726/1.png"
],
"split": "test"
},
{
"id": "CXR3845_IM-1945",
"report": "The cardiomediastinal silhouette and pulmonary vasculature are within normal limits in size. The lungs are clear of focal airspace disease, pneumothorax, or pleural effusion. There are no acute bony findings.",
"image_path": [
"CXR3845_IM-1945/0.png",
"CXR3845_IM-1945/1.png"
],
"split": "test"
},
{
"id": "CXR3403_IM-1647",
"report": "The cardiomediastinal silhouette is normal in size and contour. No focal consolidation, pneumothorax or large pleural effusion. Negative for acute displaced rib fracture.",
"image_path": [
"CXR3403_IM-1647/0.png",
"CXR3403_IM-1647/1.png"
],
"split": "test"
},
{
"id": "CXR1188_IM-0127",
"report": "Both lungs are clear and expanded. Heart and mediastinum normal.",
"image_path": [
"CXR1188_IM-0127/0.png",
"CXR1188_IM-0127/1.png"
],
"split": "test"
},
{
"id": "CXR3329_IM-1594",
"report": "The heart is normal in size and contour. There is no mediastinal widening. The lungs are clear bilaterally. No large pleural effusion or pneumothorax. The XXXX are intact.",
"image_path": [
"CXR3329_IM-1594/0.png",
"CXR3329_IM-1594/1.png"
],
"split": "test"
},
{
"id": "CXR3587_IM-1765",
"report": "The lungs are clear. The cardiomediastinal silhouette is within normal limits. No pneumothorax or pleural effusion.",
"image_path": [
"CXR3587_IM-1765/0.png",
"CXR3587_IM-1765/1.png"
],
"split": "test"
},
{
"id": "CXR1344_IM-0223",
"report": "Mediastinal contours are normal. Lungs are clear. There is no pneumothorax or large pleural effusion.",
"image_path": [
"CXR1344_IM-0223/0.png",
"CXR1344_IM-0223/1.png"
],
"split": "test"
},
{
"id": "CXR3962_IM-2027",
"report": "Heart size normal. Lungs are clear. XXXX are normal. No pneumonia, effusions, edema, pneumothorax, adenopathy, nodules or masses.",
"image_path": [
"CXR3962_IM-2027/0.png",
"CXR3962_IM-2027/1.png"
],
"split": "test"
},
{
"id": "CXR1891_IM-0580",
"report": "The heart and lungs have XXXX XXXX in the interval. Both lungs are clear and expanded. Heart and mediastinum normal.",
"image_path": [
"CXR1891_IM-0580/0.png",
"CXR1891_IM-0580/1.png"
],
"split": "test"
},
{
"id": "CXR1932_IM-0603",
"report": "Heart size and mediastinal contour are normal. Pulmonary vascularity is normal. Lungs are clear. No pleural effusions or pneumothoraces.",
"image_path": [
"CXR1932_IM-0603/0.png",
"CXR1932_IM-0603/1.png"
],
"split": "test"
},
{
"id": "CXR1510_IM-0331",
"report": "Lungs are clear bilaterally. Cardiac and mediastinal silhouettes are normal. Pulmonary vasculature is normal. No pneumothorax or pleural effusion. No acute bony abnormality.",
"image_path": [
"CXR1510_IM-0331/0.png",
"CXR1510_IM-0331/1.png"
],
"split": "test"
},
{
"id": "CXR86_IM-2380",
"report": "Heart size is within normal limits. No focal airspace consolidations. No pneumothorax or pleural effusion.",
"image_path": [
"CXR86_IM-2380/0.png",
"CXR86_IM-2380/1.png"
],
"split": "test"
},
{
"id": "CXR770_IM-2316",
"report": "Cardiac size, mediastinal contour, and pulmonary vascularity are within normal limits. No focal consolidation, suspicious pulmonary opacity, pleural effusion, or pneumothorax. The visualized osseous structures appear intact.",
"image_path": [
"CXR770_IM-2316/0.png",
"CXR770_IM-2316/1.png"
],
"split": "test"
},
{
"id": "CXR1796_IM-0517",
"report": "The lungs are clear bilaterally. Specifically, no evidence of focal consolidation, pneumothorax, or pleural effusion.. Cardio mediastinal silhouette is unremarkable. Visualized osseous structures of the thorax are without acute abnormality.",
"image_path": [
"CXR1796_IM-0517/0.png",
"CXR1796_IM-0517/1.png"
],
"split": "test"
},
{
"id": "CXR1480_IM-0311",
"report": "The heart is normal in size and contour. There is no mediastinal widening. The lungs are clear bilaterally. No large pleural effusion or pneumothorax. The XXXX are intact.",
"image_path": [
"CXR1480_IM-0311/0.png",
"CXR1480_IM-0311/1.png"
],
"split": "test"
},
{
"id": "CXR3203_IM-1513",
"report": "Cardiac and mediastinal contours are within normal limits. The lungs are clear. Bony structures are intact.",
"image_path": [
"CXR3203_IM-1513/0.png",
"CXR3203_IM-1513/1.png"
],
"split": "test"
},
{
"id": "CXR565_IM-2166",
"report": "The lungs are clear bilaterally. Specifically, no evidence of focal consolidation, pneumothorax, or pleural effusion.. Cardio mediastinal silhouette is unremarkable. Visualized osseous structures of the thorax are without acute abnormality.",
"image_path": [
"CXR565_IM-2166/0.png",
"CXR565_IM-2166/1.png"
],
"split": "test"
},
{
"id": "CXR474_IM-2101",
"report": "The lungs are clear. There is no pleural effusion or pneumothorax. The heart and mediastinum are normal. The skeletal structures are normal.",
"image_path": [
"CXR474_IM-2101/0.png",
"CXR474_IM-2101/1.png"
],
"split": "test"
},
{
"id": "CXR2861_IM-1269",
"report": "The heart size and pulmonary vascularity appear within normal limits. The lungs are free of focal airspace disease. No pleural effusion or pneumothorax is seen.",
"image_path": [
"CXR2861_IM-1269/0.png",
"CXR2861_IM-1269/1.png"
],
"split": "test"
},
{
"id": "CXR3106_IM-1456",
"report": "Cardiac and mediastinal contours are within normal limits. The lungs are clear. Bony structures are intact.",
"image_path": [
"CXR3106_IM-1456/0.png",
"CXR3106_IM-1456/1.png"
],
"split": "test"
},
{
"id": "CXR2061_IM-0698",
"report": "The heart and mediastinum are unremarkable. The lungs are clear without infiltrate. There is no effusion or pneumothorax.",
"image_path": [
"CXR2061_IM-0698/0.png",
"CXR2061_IM-0698/1.png"
],
"split": "test"
},
{
"id": "CXR39_IM-1978",
"report": "The heart and lungs have XXXX XXXX in the interval. Both lungs are clear and expanded. Heart and mediastinum normal.",
"image_path": [
"CXR39_IM-1978/0.png",
"CXR39_IM-1978/1.png"
],
"split": "test"
},
{
"id": "CXR3466_IM-1683",
"report": "The cardiomediastinal silhouette is normal in size and contour. Streaky perihilar opacities. Peribronchial cuffing also noted. No focal consolidation, pneumothorax or large pleural effusion. Normal XXXX.",
"image_path": [
"CXR3466_IM-1683/0.png",
"CXR3466_IM-1683/1.png"
],
"split": "test"
},
{
"id": "CXR1191_IM-0128",
"report": "Heart size and pulmonary vascular engorgement appear within limits of normal. Mediastinal contour is unremarkable. No focal consolidation, pleural effusion, or pneumothorax identified. No acute bony changes.",
"image_path": [
"CXR1191_IM-0128/0.png",
"CXR1191_IM-0128/1.png"
],
"split": "test"
},
{
"id": "CXR3844_IM-1945",
"report": "Lungs are clear. No pleural effusions or pneumothoraces. heart size is upper limits of normal.",
"image_path": [
"CXR3844_IM-1945/0.png",
"CXR3844_IM-1945/1.png"
],
"split": "test"
},
{
"id": "CXR1205_IM-0138",
"report": "Normal heart size. Clear lungs without pneumothorax or pleural effusion.",
"image_path": [
"CXR1205_IM-0138/0.png",
"CXR1205_IM-0138/1.png"
],
"split": "test"
},
{
"id": "CXR2948_IM-1348",
"report": "The heart size and pulmonary vascularity appear within normal limits. The lungs are free of focal airspace disease. No pleural effusion or pneumothorax is seen.",
"image_path": [
"CXR2948_IM-1348/0.png",
"CXR2948_IM-1348/1.png"
],
"split": "test"
},
{
"id": "CXR578_IM-2176",
"report": "Normal cardiomediastinal silhouette and hilar contours. The lungs are clear without focal area of consolidation, pleural effusion, or pneumothorax. Findings compatible with prior granulomatous disease. The visualized XXXX XXXX are intact without acute osseous abnormality.",
"image_path": [
"CXR578_IM-2176/0.png",
"CXR578_IM-2176/1.png"
],
"split": "test"
},
{
"id": "CXR3774_IM-1892",
"report": "Heart size is within normal limits. Tortuous aorta. Clear lungs. No pneumothorax. No pleural effusion. Atherosclerotic calcification within the aorta. Right lower lung granuloma.",
"image_path": [
"CXR3774_IM-1892/0.png",
"CXR3774_IM-1892/1.png"
],
"split": "test"
},
{
"id": "CXR3192_IM-1505",
"report": "The heart is normal in size. Mild fullness of the left hilum, small interval change from prior exam. Lucencies throughout the chest XXXX representing emphysematous change. Scattered bilateral calcified granulomas. No pneumothorax. Large hiatal hernia, increased from prior exam.",
"image_path": [
"CXR3192_IM-1505/0.png",
"CXR3192_IM-1505/1.png"
],
"split": "test"
},
{
"id": "CXR2229_IM-0831",
"report": "The heart size is normal. The mediastinal contour is within normal limits. The lungs are free of any focal infiltrates. There are no nodules or masses. No visible pneumothorax. No visible pleural fluid. The XXXX are grossly normal. There is no visible free intraperitoneal air under the diaphragm. Surgical clips are seen the right upper quadrant.",
"image_path": [
"CXR2229_IM-0831/0.png",
"CXR2229_IM-0831/1.png"
],
"split": "test"
},
{
"id": "CXR785_IM-2325",
"report": "The cardiomediastinal silhouette and pulmonary vasculature are within normal limits in size. The lungs are clear of focal airspace disease, pneumothorax, or pleural effusion. There are no acute bony findings.",
"image_path": [
"CXR785_IM-2325/0.png",
"CXR785_IM-2325/1.png"
],
"split": "test"
},
{
"id": "CXR3355_IM-1609",
"report": "Cardiomediastinal silhouettes are within normal limits. Lungs are hyperexpanded. Lungs are clear without focal consolidation, pneumothorax, or pleural effusion. Bony thorax is unremarkable.",
"image_path": [
"CXR3355_IM-1609/0.png",
"CXR3355_IM-1609/1.png"
],
"split": "test"
},
{
"id": "CXR1544_IM-0354",
"report": "Normal heart. Clear lungs. No pneumothorax. No pleural effusion.",
"image_path": [
"CXR1544_IM-0354/0.png",
"CXR1544_IM-0354/1.png"
],
"split": "test"
},
{
"id": "CXR304_IM-1413",
"report": "The XXXX examination consists of frontal and lateral radiographs of the chest. A total of 3 images were obtained. The cardiomediastinal contours are within normal limits allowing for low lung volumes and patient rotation. There is XXXX XXXX atelectasis. No consolidation, pleural effusion or pneumothorax. Calcified right infrahilar lymph XXXX again seen. Partially visualized lower cervical spine fusion XXXX.",
"image_path": [
"CXR304_IM-1413/0.png",
"CXR304_IM-1413/1.png"
],
"split": "test"
},
{
"id": "CXR692_IM-2258",
"report": "The lungs are clear. There are calcified granulomas. Heart size is normal. No pneumothorax. There are endplate changes in the spine.",
"image_path": [
"CXR692_IM-2258/0.png",
"CXR692_IM-2258/1.png"
],
"split": "test"
},
{
"id": "CXR435_IM-2075",
"report": "Lungs are clear. There is no pneumothorax or pleural effusion. The heart and mediastinum are within normal limits. Bony structures are intact.",
"image_path": [
"CXR435_IM-2075/0.png",
"CXR435_IM-2075/1.png"
],
"split": "test"
},
{
"id": "CXR1860_IM-0558",
"report": "The cardiac and mediastinal silhouettes are normal. The lungs are well-expanded and clear. There is no focal airspace opacity. There is no pneumothorax or effusion. There is dextrocurvature of the thoracic spine. There is XXXX deformity of the T9 vertebral body. Levocurvature of the lumbar spine with significant degenerative change is also noted.",
"image_path": [
"CXR1860_IM-0558/0.png",
"CXR1860_IM-0558/1.png"
],
"split": "test"
},
{
"id": "CXR3136_IM-1475",
"report": "Cardiac size, mediastinal contour, and pulmonary vascularity are within normal limits. No focal consolidation, suspicious pulmonary opacity, pleural effusion, or pneumothorax. The visualized osseous structures appear intact.",
"image_path": [
"CXR3136_IM-1475/0.png",
"CXR3136_IM-1475/1.png"
],
"split": "test"
},
{
"id": "CXR3687_IM-1838",
"report": "Heart size and mediastinal contours are within normal limits given AP projection. The right lung appears clear. There is minimal patchy atelectasis or early infiltrate in left lung base. No visible pleural effusion or pneumothorax. There is a partially visualized IVC XXXX on the lateral view. There are partially visualized surgical changes the cervical spine compatible with prior fusion procedure.",
"image_path": [
"CXR3687_IM-1838/0.png",
"CXR3687_IM-1838/1.png"
],
"split": "test"
},
{
"id": "CXR3673_IM-1828",
"report": "The heart is normal in size. The mediastinal contours are stable. Aortic calcifications are noted. There are small calcified lymph XXXX. Emphysema and chronic changes are identified. There is XXXX opacity in the left perihilar upper lobe. There is questionable XXXX extension to the pleural surface. This may represent acute infiltrate or developing density. There is no pleural effusion or pneumothorax.",
"image_path": [
"CXR3673_IM-1828/0.png",
"CXR3673_IM-1828/1.png"
],
"split": "test"
},
{
"id": "CXR1256_IM-0173",
"report": "The heart is normal in size and contour. There is mild calcification of the transverse XXXX. The lungs are clear, without evidence of infiltrate. There is no pneumothorax or effusion. Degenerative changes of the midthoracic spine are noted.",
"image_path": [
"CXR1256_IM-0173/0.png",
"CXR1256_IM-0173/1.png"
],
"split": "test"
},
{
"id": "CXR3843_IM-1944",
"report": "A right-sided chest XXXX remains in XXXX with the distal tip at the level of the mid SVC. The cardiomediastinal silhouette is within normal limits for appearance. No focal areas of pulmonary consolidation. No pulmonary nodules or mass lesions identified. No pneumothorax or pleural effusion. Mild degenerative changes of the thoracic spine.",
"image_path": [
"CXR3843_IM-1944/0.png",
"CXR3843_IM-1944/1.png"
],
"split": "test"
},
{
"id": "CXR3595_IM-1773-0001",
"report": "Stable cardiomegaly and mediastinal contour. Increased interstitial lung markings are seen, possibly due to volume overload. There is improved aeration of the lung bases with small residual left basilar effusion. No XXXX focal consolidation or pneumothorax. Stable tunneled dialysis catheter. Visualized osseous structures appear intact.",
"image_path": [
"CXR3595_IM-1773-0001/0.png",
"CXR3595_IM-1773-0001/1.png"
],
"split": "test"
},
{
"id": "CXR1675_IM-0445",
"report": "Lung volumes remain low. No infiltrates. Heart and pulmonary XXXX remain normal.",
"image_path": [
"CXR1675_IM-0445/0.png",
"CXR1675_IM-0445/1.png"
],
"split": "test"
},
{
"id": "CXR3066_IM-1430",
"report": "The heart is normal in size. The mediastinum is unremarkable. Mild emphysematous changes without focal consolidation. There is no pleural effusion. XXXX lingular scarring or atelectasis noted.",
"image_path": [
"CXR3066_IM-1430/0.png",
"CXR3066_IM-1430/1.png"
],
"split": "test"
},
{
"id": "CXR2681_IM-1154",
"report": "The heart, pulmonary XXXX and mediastinum are within normal limits. There is no pleural effusion or pneumothorax. There is no focal air space opacity to suggest a pneumonia. There is a small stable XXXX foreign body noted over the left chest. There are vascular calcifications over the aortic XXXX. There are mild degenerative changes of the spine.",
"image_path": [
"CXR2681_IM-1154/0.png",
"CXR2681_IM-1154/1.png"
],
"split": "test"
},
{
"id": "CXR2336_IM-0903",
"report": "Lungs are hyperinflated but clear. No focal infiltrate or effusion. Heart and mediastinal contours within normal limits. Calcified mediastinal XXXX identified.",
"image_path": [
"CXR2336_IM-0903/0.png",
"CXR2336_IM-0903/1.png"
],
"split": "test"
},
{
"id": "CXR3283_IM-1564",
"report": "Lungs are clear. No pleural effusions or pneumothoraces. Heart and mediastinum of normal size and contour.",
"image_path": [
"CXR3283_IM-1564/0.png",
"CXR3283_IM-1564/1.png"
],
"split": "test"
},
{
"id": "CXR569_IM-2169-0001",
"report": "The heart size and pulmonary vascularity appear within normal limits. The left hemidiaphragm remains elevated. Right base densities are again noted which appear improved. Previously seen left pleural effusion has resolved. There continues to be some left base opacities which may represent atelectasis. Surgical clips and suture lines are noted in the mediastinum. An air-fluid level is seen in the upper right abdomen immediately below the right hemidiaphragm. Extensive pleural densities are present on the right which may represent localized fluid or pleural thickening. No definite pneumothorax is seen.",
"image_path": [
"CXR569_IM-2169-0001/0.png",
"CXR569_IM-2169-0001/1.png"
],
"split": "test"
},
{
"id": "CXR1030_IM-0024",
"report": "Normal cardiomediastinal silhouette. There is no focal consolidation. There are no XXXX of a large pleural effusion. There is no pneumothorax. There is no acute bony abnormality seen. Mild degenerative changes of the spine.",
"image_path": [
"CXR1030_IM-0024/0.png",
"CXR1030_IM-0024/1.png"
],
"split": "test"
},
{
"id": "CXR1608_IM-0394",
"report": "The cardiac silhouette, upper mediastinum and pulmonary vasculature are within normal limits. There is no acute air space infiltrate, pleural effusion or pneumothorax. No pulmonary nodules are identified.",
"image_path": [
"CXR1608_IM-0394/0.png",
"CXR1608_IM-0394/1.png"
],
"split": "test"
},
{
"id": "CXR623_IM-2205",
"report": "The heart is normal in size. The mediastinum is stable. Atherosclerotic calcifications of the aorta. There is again a pleural based density in the right lung base, XXXX related to subpleural fat. The appearance is stable from multiple previous studies. The lungs are clear. There is no pleural effusion.",
"image_path": [
"CXR623_IM-2205/0.png",
"CXR623_IM-2205/1.png"
],
"split": "test"
},
{
"id": "CXR2965_IM-1358",
"report": "Heart size within normal limits. No focal airspace disease. No pleural effusion. No pneumothorax.",
"image_path": [
"CXR2965_IM-1358/0.png",
"CXR2965_IM-1358/1.png"
],
"split": "test"
},
{
"id": "CXR2876_IM-1282",
"report": "There are no focal areas of consolidation. No suspicious pulmonary opacities. Heart size within normal limits. No pleural effusions. There is no evidence of pneumothorax.",
"image_path": [
"CXR2876_IM-1282/0.png",
"CXR2876_IM-1282/1.png"
],
"split": "test"
},
{
"id": "CXR3922_IM-1996-0001",
"report": "Stable cardiomediastinal silhouette. No focal pulmonary opacity, pleural effusion or pneumothorax. No acute bony abnormality.",
"image_path": [
"CXR3922_IM-1996-0001/0.png",
"CXR3922_IM-1996-0001/1.png"
],
"split": "test"
},
{
"id": "CXR3085_IM-1444",
"report": "Normal cardiomediastinal contours. Marrow pneumothorax, focal lung consolidation or pleural effusions.",
"image_path": [
"CXR3085_IM-1444/0.png",
"CXR3085_IM-1444/1.png"
],
"split": "test"
},
{
"id": "CXR913_IM-2417",
"report": "Heart size normal. Stable cardiomediastinal silhouette. No pneumothorax, pleural effusion, or focal airspace disease. Bony structures are in XXXX alignment without fracture.",
"image_path": [
"CXR913_IM-2417/0.png",
"CXR913_IM-2417/1.png"
],
"split": "test"
},
{
"id": "CXR3474_IM-1688",
"report": "Crowded bronchovascular markings in the hilar and perihilar region, right lower lung zones. Low lung volumes. No noncalcified pulmonary nodules seen. No pleural effusion or pneumothorax. No small heart size. There is a right diaphragmatic hump. The soft tissues seen in the left cardiophrenic XXXX, could represent an ectatic descending aorta or hiatal hernia. Visualized XXXX of the chest XXXX are within normal limits. Degenerative changes demonstrated within the visualized thoracic spine.",
"image_path": [
"CXR3474_IM-1688/0.png",
"CXR3474_IM-1688/1.png"
],
"split": "test"
},
{
"id": "CXR2146_IM-0766",
"report": "Cardiac and mediastinal contours are within normal limits. The lungs are clear. Bony structures are intact.",
"image_path": [
"CXR2146_IM-0766/0.png",
"CXR2146_IM-0766/1.png"
],
"split": "test"
},
{
"id": "CXR1742_IM-0489",
"report": "Heart size mildly enlarged. No alveolar consolidation, no findings of pleural effusion or pulmonary edema. No pneumothorax. S-shaped spine curvature noted.",
"image_path": [
"CXR1742_IM-0489/0.png",
"CXR1742_IM-0489/1.png"
],
"split": "test"
},
{
"id": "CXR1642_IM-0421",
"report": "Lungs are clear. No pleural effusions or pneumothoraces. Heart size is normal with postoperative changes consistent with CABG. Degenerative changes in the thoracic spine.",
"image_path": [
"CXR1642_IM-0421/0.png",
"CXR1642_IM-0421/1.png"
],
"split": "test"
},
{
"id": "CXR2363_IM-0926",
"report": "Heart size is upper limits of normal. The pulmonary XXXX and mediastinum are within normal limits. There is no pleural effusion or pneumothorax. There is right basilar air space opacity.",
"image_path": [
"CXR2363_IM-0926/0.png",
"CXR2363_IM-0926/1.png"
],
"split": "test"
},
{
"id": "CXR3508_IM-1710",
"report": "The heart is normal in size. The cardiomediastinal contours are stable. There are stable bilateral pleural effusions with partial right-sided loculation. Biapical scarring and pleural thickening appears stable. There is again right-sided superior hilar retraction and mild rightward XXXX deviation. No acute infiltrate is appreciated.",
"image_path": [
"CXR3508_IM-1710/0.png",
"CXR3508_IM-1710/1.png"
],
"split": "test"
},
{
"id": "CXR2918_IM-1320",
"report": "Cardiomediastinal silhouette is normal. Pulmonary vasculature and XXXX are normal. No consolidation, pneumothorax or large pleural effusion. Osseous structures and soft tissues are normal.",
"image_path": [
"CXR2918_IM-1320/0.png",
"CXR2918_IM-1320/1.png"
],
"split": "test"
},
{
"id": "CXR2088_IM-0719",
"report": "Compared to prior examination from XXXX, there has been extubation and removal of central line and enteric tube. Stable cardiomegaly and mild thoracolumbar dextroscoliosis. Left basilar opacity XXXX represents chronic fibrosis/scar. No focal consolidation, pneumothorax, or effusion. No acute osseous abnormality.",
"image_path": [
"CXR2088_IM-0719/0.png",
"CXR2088_IM-0719/1.png"
],
"split": "test"
},
{
"id": "CXR1765_IM-0499",
"report": "The cardiomediastinal silhouette is within normal limits. There is rounded calcified density within the left lower lobe most consistent with granuloma. Remaining lungs are clear without evidence of focal opacification. No pneumothorax or large pleural effusion. No acute bone abnormality.",
"image_path": [
"CXR1765_IM-0499/0.png",
"CXR1765_IM-0499/1.png"
],
"split": "test"
},
{
"id": "CXR1470_IM-0303",
"report": "Mediastinal contours are normal. Lungs are clear. There is no pneumothorax or large pleural effusion.",
"image_path": [
"CXR1470_IM-0303/0.png",
"CXR1470_IM-0303/1.png"
],
"split": "test"
},
{
"id": "CXR3775_IM-1893",
"report": "No focal lung consolidation. Heart size and pulmonary vascularity are within normal limits. No pneumothorax or pleural effusion. Osseous structures are grossly intact.",
"image_path": [
"CXR3775_IM-1893/0.png",
"CXR3775_IM-1893/1.png"
],
"split": "test"
},
{
"id": "CXR3521_IM-1719",
"report": "The XXXX examination consists of frontal and lateral radiographs of the chest. The cardiomediastinal contours are within normal limits. There is right greater than left biapical bullous emphysema. No focal consolidation, pleural effusion, or pneumothorax identified. There are XXXX degenerative changes of the thoracic spine.",
"image_path": [
"CXR3521_IM-1719/0.png",
"CXR3521_IM-1719/1.png"
],
"split": "test"
},
{
"id": "CXR3382_IM-1629-0001",
"report": "Prominent interstitial markings. There are small bilateral pleural effusions. No pneumothorax or focal consolidation. Normal heart size. Catheter tubing present in the upper midabdomen. There is bilateral acromioclavicular degenerative joint disease, right greater than left.",
"image_path": [
"CXR3382_IM-1629-0001/0.png",
"CXR3382_IM-1629-0001/1.png"
],
"split": "test"
},
{
"id": "CXR1015_IM-0001",
"report": "Streaky and patchy bibasilar opacities, triangular density projected over the heart on the lateral view. No definite pleural effusion seen, no typical findings of pulmonary edema. Considering differences in technical factors XXXX stable cardiomediastinal silhouette with normal heart size.",
"image_path": [
"CXR1015_IM-0001/0.png",
"CXR1015_IM-0001/1.png"
],
"split": "test"
},
{
"id": "CXR2537_IM-1049",
"report": "Frontal and lateral views of the chest show an unchanged cardiomediastinal silhouette. Right-sided aortic XXXX. Normal mediastinal contour, pulmonary XXXX and vasculature, central airways and aeration of the lungs. There is right basal XXXX patchy opacity and bibasal atelectasis or scarring. There is no pleural effusion or pneumothorax. Right apical calcified granuloma noted.",
"image_path": [
"CXR2537_IM-1049/0.png",
"CXR2537_IM-1049/1.png"
],
"split": "test"
},
{
"id": "CXR1460_IM-0298",
"report": "Cardiac and mediastinal contours are within normal limits. The lungs are clear. Bony structures are intact.",
"image_path": [
"CXR1460_IM-0298/0.png",
"CXR1460_IM-0298/1.png"
],
"split": "test"
},
{
"id": "CXR1319_IM-0205",
"report": "The heart size and pulmonary vascularity appear within normal limits. The lungs are free of focal airspace disease. No pleural effusion or pneumothorax is seen.",
"image_path": [
"CXR1319_IM-0205/0.png",
"CXR1319_IM-0205/1.png"
],
"split": "test"
},
{
"id": "CXR3993_IM-2044",
"report": "The heart is mildly enlarged. Left hemidiaphragm is elevated. There is no acute infiltrate or pleural effusion. The mediastinum is unremarkable.",
"image_path": [
"CXR3993_IM-2044/0.png",
"CXR3993_IM-2044/1.png"
],
"split": "test"
},
{
"id": "CXR988_IM-2474",
"report": "Lungs are clear. No focal infiltrate. No pleural effusion or pneumothorax. Normal cardiomediastinal silhouette.",
"image_path": [
"CXR988_IM-2474/0.png",
"CXR988_IM-2474/1.png"
],
"split": "test"
},
{
"id": "CXR2445_IM-0981",
"report": "The heart is normal in size. The mediastinum is unremarkable. The lungs are clear.",
"image_path": [
"CXR2445_IM-0981/0.png",
"CXR2445_IM-0981/1.png"
],
"split": "test"
},
{
"id": "CXR1193_IM-0129",
"report": "Stable enlarged cardiac silhouette. Persistent bilateral lower lobe airspace disease, not significantly XXXX compared to prior. No pleural effusion or pneumothorax. No acute bony abnormality.",
"image_path": [
"CXR1193_IM-0129/0.png",
"CXR1193_IM-0129/1.png"
],
"split": "test"
},
{
"id": "CXR3472_IM-1688",
"report": "The cardiomediastinal silhouette and vasculature are within normal limits for size and contour. The lungs are normally inflated and clear. Osseous structures are within normal limits for patient age.",
"image_path": [
"CXR3472_IM-1688/0.png",
"CXR3472_IM-1688/1.png"
],
"split": "test"
},
{
"id": "CXR850_IM-2373-0001",
"report": "Stable appearance of the cardiomediastinal silhouette. There is no pneumothorax, pleural effusion, or focal airspace consolidation.",
"image_path": [
"CXR850_IM-2373-0001/0.png",
"CXR850_IM-2373-0001/1.png"
],
"split": "test"
},
{
"id": "CXR1277_IM-0185",
"report": "PA and lateral views the chest were obtained. The cardiomediastinal silhouette is normal in size and configuration. The lungs are well aerated. No pneumothorax, pleural effusion, or lobar air space consolidation. XXXX right middle lobe collapse appears less distinct than on prior study.",
"image_path": [
"CXR1277_IM-0185/0.png",
"CXR1277_IM-0185/1.png"
],
"split": "test"
},
{
"id": "CXR2145_IM-0766",
"report": "The cardiomediastinal silhouette is normal. The lungs are clear. There is no pneumothorax or pneumomediastinum. Visualized bony structures are normal.",
"image_path": [
"CXR2145_IM-0766/0.png",
"CXR2145_IM-0766/1.png"
],
"split": "test"
},
{
"id": "CXR3016_IM-1392",
"report": "Cardiac and mediastinal contours are within normal limits. Prior granulomatous disease. The lungs are clear. Thoracic spondylosis.",
"image_path": [
"CXR3016_IM-1392/0.png",
"CXR3016_IM-1392/1.png"
],
"split": "test"
},
{
"id": "CXR308_IM-1439",
"report": "Stable appearing right-sided XXXX the opacities. There is persistent elevation of the right hemidiaphragm. The cardiac silhouette and mediastinal contours are within normal limits. There is no pneumothorax.",
"image_path": [
"CXR308_IM-1439/0.png",
"CXR308_IM-1439/1.png"
],
"split": "test"
},
{
"id": "CXR1377_IM-0242",
"report": "The heart size is normal. The mediastinal contour is within normal limits. The lungs are free of any focal infiltrates. There are no nodules or masses. No visible pneumothorax. No visible pleural fluid. The XXXX are grossly normal. There is no visible free intraperitoneal air under the diaphragm.",
"image_path": [
"CXR1377_IM-0242/0.png",
"CXR1377_IM-0242/1.png"
],
"split": "test"
},
{
"id": "CXR2209_IM-0816",
"report": "The heart is normal in size. The mediastinum is unremarkable. Emphysematous changes are identified. The lungs are otherwise grossly clear.",
"image_path": [
"CXR2209_IM-0816/0.png",
"CXR2209_IM-0816/1.png"
],
"split": "test"
},
{
"id": "CXR3221_IM-1522",
"report": "The lungs are clear bilaterally. Specifically, no evidence of focal consolidation, pneumothorax, or pleural effusion.. Cardio mediastinal silhouette is unremarkable. Visualized osseous structures of the thorax are without acute abnormality.",
"image_path": [
"CXR3221_IM-1522/0.png",
"CXR3221_IM-1522/1.png"
],
"split": "test"
},
{
"id": "CXR2433_IM-0975",
"report": "Low lung volumes with bibasilar subsegmental atelectasis. No focal consolidations, pleural effusions, or pneumothoraces. Cardiomediastinal silhouette is within normal limits. Degenerative changes of the thoracic spine.",
"image_path": [
"CXR2433_IM-0975/0.png",
"CXR2433_IM-0975/1.png"
],
"split": "test"
},
{
"id": "CXR2575_IM-1075",
"report": "The lungs are clear. Heart size is normal. No pneumothorax. There are endplate changes within the spine.",
"image_path": [
"CXR2575_IM-1075/0.png",
"CXR2575_IM-1075/1.png"
],
"split": "test"
},
{
"id": "CXR761_IM-2310",
"report": "Lung volumes are low. No focal infiltrates. Heart size normal.",
"image_path": [
"CXR761_IM-2310/0.png",
"CXR761_IM-2310/1.png"
],
"split": "test"
},
{
"id": "CXR2531_IM-1045",
"report": "The lungs are clear bilaterally. Specifically, no evidence of focal consolidation, pneumothorax, or pleural effusion.. Scattered calcified granulomas noted. Cardio mediastinal silhouette is unremarkable. Visualized osseous structures of the thorax demonstrate mild multilevel degenerative disc disease of the thoracolumbar spine without acute abnormality.",
"image_path": [
"CXR2531_IM-1045/0.png",
"CXR2531_IM-1045/1.png"
],
"split": "test"
},
{
"id": "CXR3415_IM-1650",
"report": "No acute osseous abnormality. Mild degenerative changes of the thoracic spine. Stable normal cardiomediastinal silhouette and hilar contours. Prominence of superior mediastinal, XXXX superimposed structures. No focal area of consolidation, pleural effusion, or pneumothorax. Mild bibasilar atelectasis.",
"image_path": [
"CXR3415_IM-1650/0.png",
"CXR3415_IM-1650/1.png"
],
"split": "test"
},
{
"id": "CXR2378_IM-0938",
"report": "Cardiomediastinal silhouettes are within normal limits. Lungs are clear without focal consolidation, pneumothorax, or pleural effusion. Stable left lower lobe calcified granuloma. Remote left clavicle fracture.",
"image_path": [
"CXR2378_IM-0938/0.png",
"CXR2378_IM-0938/1.png"
],
"split": "test"
},
{
"id": "CXR980_IM-2468",
"report": "Heart size and mediastinal contours appear within normal limits. Pulmonary vascularity is within normal limits. No focal consolidation, suspicious pulmonary opacity, pneumothorax or definite pleural effusion. Visualized osseous structures appear intact.",
"image_path": [
"CXR980_IM-2468/0.png",
"CXR980_IM-2468/1.png"
],
"split": "test"
},
{
"id": "CXR2159_IM-0776",
"report": "The lungs and pleural spaces show no acute abnormality. Heart size and pulmonary vascularity within normal limits. .",
"image_path": [
"CXR2159_IM-0776/0.png",
"CXR2159_IM-0776/1.png"
],
"split": "test"
},
{
"id": "CXR877_IM-2392",
"report": "XXXX sternotomy XXXX appear intact. Surgical clips overlying the mediastinum. Mitral valve replacement seen. Low lung volumes. The interstitial markings appear prominent, which may represent interstitial edema. There is mild blunting of the posterior sulcus on the lateral view, which could represent a small effusion. No pneumothorax. No acute bony abnormality.",
"image_path": [
"CXR877_IM-2392/0.png",
"CXR877_IM-2392/1.png"
],
"split": "test"
},
{
"id": "CXR2401_IM-0950",
"report": "Cardiomediastinal silhouette is within normal limits of size and appearance. The pulmonary vascularity is unremarkable. Lungs are expanded and clear airspace disease. Negative for pneumothorax, pleural effusion, or pneumoperitoneum. Limited bone evaluation reveals no acute abnormality.",
"image_path": [
"CXR2401_IM-0950/0.png",
"CXR2401_IM-0950/1.png"
],
"split": "test"
},
{
"id": "CXR535_IM-2142",
"report": "There is S-shaped thoracolumbar scoliosis. There are T-spine osteophytes. XXXX opacity in the left lower lobe XXXX represents atelectasis or scarring. There is no pneumothorax. There is no large pleural effusion. The cardiomediastinal silhouette is within normal limits. There is no lobar pneumonia. There are calcified hilar lymph XXXX.",
"image_path": [
"CXR535_IM-2142/0.png",
"CXR535_IM-2142/1.png"
],
"split": "test"
},
{
"id": "CXR1269_IM-0181",
"report": "Normal heart size. Hyperexpanded lungs without focal consolidation, pneumothorax or large pleural effusion. Left nipple silhouette visualized. Negative for acute bone abnormality.",
"image_path": [
"CXR1269_IM-0181/0.png",
"CXR1269_IM-0181/1.png"
],
"split": "test"
},
{
"id": "CXR427_IM-2070",
"report": "The cardiomediastinal silhouette is within normal limits for size and contour. The lungs are normally inflated without evidence of focal airspace disease, pleural effusion, or pneumothorax. Osseous structures are within normal limits for patient age..",
"image_path": [
"CXR427_IM-2070/0.png",
"CXR427_IM-2070/1.png"
],
"split": "test"
},
{
"id": "CXR2314_IM-0889",
"report": "The lungs are XXXX. XXXX opacities are present in the right costophrenic XXXX. No focal infiltrates. Heart size normal.",
"image_path": [
"CXR2314_IM-0889/0.png",
"CXR2314_IM-0889/1.png"
],
"split": "test"
},
{
"id": "CXR891_IM-2403",
"report": "The heart size and pulmonary vascularity appear within normal limits. The lungs are free of focal airspace disease. No pleural effusion or pneumothorax is seen.",
"image_path": [
"CXR891_IM-2403/0.png",
"CXR891_IM-2403/1.png"
],
"split": "test"
},
{
"id": "CXR1126_IM-0082",
"report": "XXXX sternotomy XXXX and mediastinal surgical clips remain in XXXX. The cardiomediastinal silhouette is stable in appearance. The thoracic aorta is tortuous and calcified with stable appearance since XXXX exam. No focal areas of pulmonary consolidation. Scattered right basilar subsegmental atelectasis. The left lung appears clear. No pneumothorax or pleural effusion present. Moderate degenerative changes of the thoracic spine. Osteopenia. Mild loss of XXXX of a mid thoracic vertebral body.",
"image_path": [
"CXR1126_IM-0082/0.png",
"CXR1126_IM-0082/1.png"
],
"split": "test"
},
{
"id": "CXR136_IM-0233",
"report": "Heart size normal. Lungs are clear. XXXX are normal. No pneumonia, effusions, edema, pneumothorax, adenopathy, nodules or masses.",
"image_path": [
"CXR136_IM-0233/0.png",
"CXR136_IM-0233/1.png"
],
"split": "test"
},
{
"id": "CXR2768_IM-1212",
"report": "XXXX XXXX and lateral chest examination was obtained. The heart silhouette is normal in size and contour. Aortic XXXX appear unremarkable. Lungs demonstrate no acute findings. There is no effusion or pneumothorax.",
"image_path": [
"CXR2768_IM-1212/0.png",
"CXR2768_IM-1212/1.png"
],
"split": "test"
},
{
"id": "CXR1950_IM-0618",
"report": "Cardiac and mediastinal contours are unremarkable. Pulmonary vascularity is within normal limits. No focal air space opacities, pleural effusion, or pneumothorax. XXXX are grossly unremarkable.",
"image_path": [
"CXR1950_IM-0618/0.png",
"CXR1950_IM-0618/1.png"
],
"split": "test"
},
{
"id": "CXR1399_IM-0255",
"report": "The cardiac contours are normal. The lungs are clear. Thoracic spondylosis. Partial fusion of 2 vertebral bodies near the thoracolumbar junction.",
"image_path": [
"CXR1399_IM-0255/0.png",
"CXR1399_IM-0255/1.png"
],
"split": "test"
},
{
"id": "CXR922_IM-2423",
"report": "The heart is slightly large. Pulmonary XXXX are normal. No infiltrates.",
"image_path": [
"CXR922_IM-2423/0.png",
"CXR922_IM-2423/1.png"
],
"split": "test"
},
{
"id": "CXR2446_IM-0982",
"report": "The heart and lungs have XXXX XXXX in the interval. Both lungs are clear and expanded. The aorta is tortuous, but the heart and mediastinum otherwise normal.",
"image_path": [
"CXR2446_IM-0982/0.png",
"CXR2446_IM-0982/1.png"
],
"split": "test"
},
{
"id": "CXR2983_IM-1371",
"report": "Cardiomediastinal silhouette is within normal limits. No focal consolidation. There is right lower lobe scarring. No pneumothorax or large pleural effusion. Granulomas present. No acute bony abnormalities.",
"image_path": [
"CXR2983_IM-1371/0.png",
"CXR2983_IM-1371/1.png"
],
"split": "test"
},
{
"id": "CXR3281_IM-1562",
"report": "The heart size is within normal limits. Cardiomediastinal contour is normal. There is a right upper lobe nodule measuring 8 mm in diameter. Trachea is midline. The lungs otherwise clear. XXXX and soft tissues are unremarkable.",
"image_path": [
"CXR3281_IM-1562/0.png",
"CXR3281_IM-1562/1.png"
],
"split": "test"
},
{
"id": "CXR3716_IM-1856",
"report": "The cardiomediastinal silhouette is normal in size and contour. No focal consolidation, pneumothorax or large pleural effusion. Negative for acute displaced rib fracture. Bilateral nipple jewelry.",
"image_path": [
"CXR3716_IM-1856/0.png",
"CXR3716_IM-1856/1.png"
],
"split": "test"
},
{
"id": "CXR3124_IM-1468",
"report": "There is persistent, marked enlargement of the pulmonary arteries. Normal heart size. No focal airspace consolidation. No pleural effusion or pneumothorax. Visualized osseous structures are unremarkable in appearance.",
"image_path": [
"CXR3124_IM-1468/0.png",
"CXR3124_IM-1468/1.png"
],
"split": "test"
},
{
"id": "CXR2866_IM-1273",
"report": "Heart size normal. Lungs are clear. XXXX are normal. No pneumonia, effusions, edema, pneumothorax, adenopathy, nodules or masses.",
"image_path": [
"CXR2866_IM-1273/0.png",
"CXR2866_IM-1273/1.png"
],
"split": "test"
},
{
"id": "CXR2327_IM-0898",
"report": "There has been interval development of a large right-sided pleural effusion. The left lung is clear. There is no pneumothorax. Heart size mediastinal contours are within normal limits. XXXX deformity is noted at the upper thoracic vertebral body.",
"image_path": [
"CXR2327_IM-0898/0.png",
"CXR2327_IM-0898/1.png"
],
"split": "test"
},
{
"id": "CXR708_IM-2271",
"report": "No pleural effusion, pneumothorax or focal airspace opacities. Cardiomediastinal silhouette is within normal limits. The trachea is midline. No free subdiaphragmatic air. The included osseous structures are grossly intact.",
"image_path": [
"CXR708_IM-2271/0.png",
"CXR708_IM-2271/1.png"
],
"split": "test"
},
{
"id": "CXR3546_IM-1738",
"report": "Unchanged cardiomegaly. There is continued interstitial prominence bilaterally. Unchanged vascular appearance. There is patchy retrocardiac opacity. Negative for pneumothorax.",
"image_path": [
"CXR3546_IM-1738/0.png",
"CXR3546_IM-1738/1.png"
],
"split": "test"
},
{
"id": "CXR3707_IM-1851",
"report": "There may be a subtle airspace opacity in the right base near the midclavicular line. There is no pleural effusion or pneumothorax. The heart and mediastinum are normal. The skeletal structures are normal.",
"image_path": [
"CXR3707_IM-1851/0.png",
"CXR3707_IM-1851/1.png"
],
"split": "test"
},
{
"id": "CXR831_IM-2358",
"report": "The cardiomediastinal silhouette is normal in size and contour. Low lung volumes without focal consolidation, pneumothorax or large pleural effusion. Normal XXXX.",
"image_path": [
"CXR831_IM-2358/0.png",
"CXR831_IM-2358/1.png"
],
"split": "test"
},
{
"id": "CXR3691_IM-1842",
"report": "The heart is normal in size. The mediastinum is stable. Atherosclerotic calcifications of the aorta identified. There is no focal consolidation, pleural effusion or pneumothorax. Degenerative changes of the thoracic spine are noted.",
"image_path": [
"CXR3691_IM-1842/0.png",
"CXR3691_IM-1842/1.png"
],
"split": "test"
},
{
"id": "CXR404_IM-2052",
"report": "Artifact in the region of the central upper abdomen. No focal areas of consolidation. No pleural effusions. No evidence of pneumothorax. Heart size within normal limits. Osseous structures intact.",
"image_path": [
"CXR404_IM-2052/0.png",
"CXR404_IM-2052/1.png"
],
"split": "test"
},
{
"id": "CXR2727_IM-1187",
"report": "Heart size is normal. Cardiomediastinal silhouette stable. No pneumothorax, pleural effusion, or focal airspace disease. Nodular densities consistent with chronic granulomatous disease. Bony structures appear intact. Emphysema.",
"image_path": [
"CXR2727_IM-1187/0.png",
"CXR2727_IM-1187/1.png"
],
"split": "test"
},
{
"id": "CXR1899_IM-0582",
"report": "The lungs are clear bilaterally. Specifically, no evidence of focal consolidation, pneumothorax, or pleural effusion.. Cardio mediastinal silhouette is unremarkable. Visualized osseous structures of the thorax are without acute abnormality.",
"image_path": [
"CXR1899_IM-0582/0.png",
"CXR1899_IM-0582/1.png"
],
"split": "test"
},
{
"id": "CXR2424_IM-0966",
"report": "The lungs are clear. There is no pleural effusion or pneumothorax. The heart is not significantly enlarged. The mediastinum is normal. Arthritic changes of the skeletal structures are noted.",
"image_path": [
"CXR2424_IM-0966/0.png",
"CXR2424_IM-0966/1.png"
],
"split": "test"
},
{
"id": "CXR1530_IM-0344",
"report": "Mediastinal contours are normal. Lungs are clear. There is no pneumothorax or large pleural effusion.",
"image_path": [
"CXR1530_IM-0344/0.png",
"CXR1530_IM-0344/1.png"
],
"split": "test"
},
{
"id": "CXR2797_IM-1229",
"report": "The trachea is midline. The cardiomediastinal silhouette is normal. The lungs are clear, without evidence of acute infiltrate or effusion. There is no pneumothorax. Visualized bony structures reveal no acute abnormalities.",
"image_path": [
"CXR2797_IM-1229/0.png",
"CXR2797_IM-1229/1.png"
],
"split": "test"
},
{
"id": "CXR617_IM-2200",
"report": "Lungs are clear. No pleural effusions or pneumothoraces. heart and mediastinum are stable with normal sized heart. Degenerative changes in the spine.",
"image_path": [
"CXR617_IM-2200/0.png",
"CXR617_IM-2200/1.png"
],
"split": "test"
},
{
"id": "CXR3784_IM-1898",
"report": "AP view was obtained due to patient condition. Low volume lungs. No focal lung consolidation. The heart is not enlarged. No pleural effusion.",
"image_path": [
"CXR3784_IM-1898/0.png",
"CXR3784_IM-1898/1.png"
],
"split": "test"
},
{
"id": "CXR1799_IM-0519",
"report": "Heart size within normal limits. No focal airspace disease. No pneumothorax or pleural effusion.",
"image_path": [
"CXR1799_IM-0519/0.png",
"CXR1799_IM-0519/1.png"
],
"split": "test"
},
{
"id": "CXR3885_IM-1971",
"report": "The heart, pulmonary XXXX and mediastinum are within normal limits. There is no pleural effusion or pneumothorax. There is no focal air space opacity to suggest a pneumonia.",
"image_path": [
"CXR3885_IM-1971/0.png",
"CXR3885_IM-1971/1.png"
],
"split": "test"
},
{
"id": "CXR3340_IM-1601",
"report": "The cardiomediastinal silhouette is normal in size and contour. Atherosclerosis of the aortic XXXX. Minimal XXXX densities, left lung base. Hyperexpanded lungs. No focal consolidation, pneumothorax or large pleural effusion. Negative for acute bone abnormality.",
"image_path": [
"CXR3340_IM-1601/0.png",
"CXR3340_IM-1601/1.png"
],
"split": "test"
},
{
"id": "CXR2129_IM-0753",
"report": "The heart is normal in size and contour. The lungs are clear, without evidence of infiltrate. There is no pneumothorax or effusion.",
"image_path": [
"CXR2129_IM-0753/0.png",
"CXR2129_IM-0753/1.png"
],
"split": "test"
},
{
"id": "CXR584_IM-2181",
"report": "There are no focal areas of consolidation. No suspicious pulmonary opacities. Heart size within normal limits. No pleural effusions. No evidence of pneumothorax. Osseous structures intact.",
"image_path": [
"CXR584_IM-2181/0.png",
"CXR584_IM-2181/1.png"
],
"split": "test"
},
{
"id": "CXR251_IM-1032",
"report": "The heart is normal in size. The mediastinum is unremarkable. Mild hyperinflation is noted. There are granulomatous sequela. No acute infiltrate or significant pleural effusion are noted. The costophrenic XXXX are excluded.",
"image_path": [
"CXR251_IM-1032/0.png",
"CXR251_IM-1032/1.png"
],
"split": "test"
},
{
"id": "CXR1210_IM-0142",
"report": "The heart, pulmonary XXXX and mediastinum are within normal limits. There is no pleural effusion or pneumothorax. There is no focal air space opacity to suggest a pneumonia. There mild degenerative changes of the thoracic spine. There is a slight XXXX deformity of the lower thoracic body which is age-indeterminate.",
"image_path": [
"CXR1210_IM-0142/0.png",
"CXR1210_IM-0142/1.png"
],
"split": "test"
},
{
"id": "CXR3025_IM-1400",
"report": "The lungs are clear bilaterally. Specifically, no evidence of focal consolidation, pneumothorax, or pleural effusion.. Cardio mediastinal silhouette is unremarkable. Visualized osseous structures of the thorax are without acute abnormality. No acute displaced rib fractures.",
"image_path": [
"CXR3025_IM-1400/0.png",
"CXR3025_IM-1400/1.png"
],
"split": "test"
},
{
"id": "CXR2713_IM-1180",
"report": "The heart is normal in size and contour. The aorta is calcified and tortuous. The lung volumes are low. There is elevation of the right hemidiaphragm. Minimal streaky opacities in the lung bases, XXXX subsegmental atelectasis. No pleural effusion or pneumothorax.",
"image_path": [
"CXR2713_IM-1180/0.png",
"CXR2713_IM-1180/1.png"
],
"split": "test"
},
{
"id": "CXR3088_IM-1444",
"report": "Heart size and mediastinal contours appear within normal limits. No focal pulmonary opacity, pleural effusion or pneumothorax. There is levoscoliosis of the thoracic spine.",
"image_path": [
"CXR3088_IM-1444/0.png",
"CXR3088_IM-1444/1.png"
],
"split": "test"
},
{
"id": "CXR1471_IM-0304",
"report": "The cardiomediastinal silhouette is within normal limits for appearance. The lungs are hyperexpanded with flattening of the bilateral hemidiaphragms. Mild increased lung markings XXXX due to chronic changes. No focal pulmonary consolidation. No pneumothorax. No pleural effusion. Moderate degenerative changes of the thoracic spine. Calcified left perihilar granuloma redemonstrated.",
"image_path": [
"CXR1471_IM-0304/0.png",
"CXR1471_IM-0304/1.png"
],
"split": "test"
},
{
"id": "CXR387_IM-1962",
"report": "Heart size is normal. There is left hilar enlargement with partial opacification of the left upper lobe suggestive of hilar mass with obstructive atelectasis. Questionable small right midlung nodule. Negative for pneumothorax or pleural effusion. Bony thorax is unremarkable.",
"image_path": [
"CXR387_IM-1962/0.png",
"CXR387_IM-1962/1.png"
],
"split": "test"
},
{
"id": "CXR3712_IM-1854",
"report": "Changes of renal osteodystrophy are noted. Heart size and pulmonary vascularity appear within normal limits. The lungs are free of focal airspace disease. No pleural effusion or pneumothorax is seen.",
"image_path": [
"CXR3712_IM-1854/0.png",
"CXR3712_IM-1854/1.png"
],
"split": "test"
},
{
"id": "CXR184_IM-0544",
"report": "PA and lateral views were obtained. Lungs are clear. There is no pneumothorax or pleural effusion. The heart and mediastinum are within normal limits. Bony structures are intact. A 5 mm stable right apical nodule.",
"image_path": [
"CXR184_IM-0544/0.png",
"CXR184_IM-0544/1.png"
],
"split": "test"
},
{
"id": "CXR1046_IM-0036",
"report": "Heart and mediastinum within normal limits. Negative for focal pulmonary consolidation, pleural effusion, or pneumothorax.",
"image_path": [
"CXR1046_IM-0036/0.png",
"CXR1046_IM-0036/1.png"
],
"split": "test"
},
{
"id": "CXR757_IM-2308",
"report": "Heart size is normal. The lungs are clear. There are no focal air space consolidations. No pleural effusions or pneumothoraces. The hilar and mediastinal contours are unchanged. Normal pulmonary vascularity. Stable postsurgical changes of the lower cervical spine.",
"image_path": [
"CXR757_IM-2308/0.png",
"CXR757_IM-2308/1.png"
],
"split": "test"
},
{
"id": "CXR2559_IM-1063",
"report": "The heart size and pulmonary vascularity appear within normal limits. The lungs are free of focal airspace disease. No pleural effusion or pneumothorax is seen.",
"image_path": [
"CXR2559_IM-1063/0.png",
"CXR2559_IM-1063/1.png"
],
"split": "test"
},
{
"id": "CXR1570_IM-0372",
"report": "Evaluation for pneumothorax is limited due to exclusion of the superior-most pulmonary apices. No visible pleural XXXX. No focal air space opacities or pleural effusion. Cardiomediastinal silhouette is within normal limits. No free subdiaphragmatic air. Mild degenerative changes of the thoracic spine. Included osseous structures are grossly intact.",
"image_path": [
"CXR1570_IM-0372/0.png",
"CXR1570_IM-0372/1.png"
],
"split": "test"
},
{
"id": "CXR3155_IM-1486",
"report": "Heart size mildly enlarged with enlarged right atrium. No focal alveolar consolidation, no definite pleural effusion seen. No pneumothorax.",
"image_path": [
"CXR3155_IM-1486/0.png",
"CXR3155_IM-1486/1.png"
],
"split": "test"
},
{
"id": "CXR1622_IM-0404",
"report": "The cardiomediastinal silhouette is within normal limits for size and contour. The lungs are normally inflated without evidence of focal airspace disease, pleural effusion, or pneumothorax. No acute osseus abnormality..",
"image_path": [
"CXR1622_IM-0404/0.png",
"CXR1622_IM-0404/1.png"
],
"split": "test"
},
{
"id": "CXR2545_IM-1054",
"report": "The trachea is midline. The cardiomediastinal silhouette is normal. Lung XXXX are clear without evidence of effusion, infiltrate, or pneumothorax. Visualized bony structures are intact. Visualized soft tissues appear normal.",
"image_path": [
"CXR2545_IM-1054/0.png",
"CXR2545_IM-1054/1.png"
],
"split": "test"
},
{
"id": "CXR2168_IM-0784",
"report": "The heart size is within normal limits. Negative for focal pulmonary consolidation, pleural effusion, or pneumothorax.",
"image_path": [
"CXR2168_IM-0784/0.png",
"CXR2168_IM-0784/1.png"
],
"split": "test"
},
{
"id": "CXR2190_IM-0800",
"report": "Lungs are clear. No pleural effusions or pneumothoraces. Heart and mediastinum of normal size and contour. Degenerative changes in the spine. spinal stimulator is in XXXX with tip overlying the T9 vertebral body.",
"image_path": [
"CXR2190_IM-0800/0.png",
"CXR2190_IM-0800/1.png"
],
"split": "test"
},
{
"id": "CXR3391_IM-1637",
"report": "There are no focal areas of consolidation. No suspicious pulmonary opacities. Heart size within normal limits. No pleural effusions. There is no evidence of pneumothorax. Stable left mid lung granuloma.",
"image_path": [
"CXR3391_IM-1637/0.png",
"CXR3391_IM-1637/1.png"
],
"split": "test"
},
{
"id": "CXR1404_IM-0258",
"report": "No focal lung consolidation. Heart size and pulmonary vascularity are within normal limits. No pneumothorax or pleural effusion. No acute bony abnormalities. There are stable anterior wedge XXXX deformities of 2 midthoracic vertebral bodies.",
"image_path": [
"CXR1404_IM-0258/0.png",
"CXR1404_IM-0258/1.png"
],
"split": "test"
},
{
"id": "CXR1197_IM-0131",
"report": "XXXX XXXX and lateral chest examination was obtained. The heart silhouette is normal in size and contour. Aortic XXXX appear unremarkable. Lungs demonstrate no acute findings. There is no effusion or pneumothorax. Bilateral prominent lung vascularity medially, unchanged.",
"image_path": [
"CXR1197_IM-0131/0.png",
"CXR1197_IM-0131/1.png"
],
"split": "test"
},
{
"id": "CXR356_IM-1744",
"report": "The cardiomediastinal silhouette is within normal limits for size and contour. The lungs are normally inflated without evidence of focal airspace disease, pleural effusion, or pneumothorax. Osseous structures are within normal limits for patient age..",
"image_path": [
"CXR356_IM-1744/0.png",
"CXR356_IM-1744/1.png"
],
"split": "test"
},
{
"id": "CXR800_IM-2334",
"report": "The lungs and pleural spaces show no acute abnormality. Heart size is enlarged, pulmonary vascularity within normal limits. Marked tortuosity of the thoracic aorta. There are advanced degenerative changes of the glenohumeral joints bilaterally with bone-on-bone articulation, remodeling of the glenoid, and extensive subchondral cystic change. No displaced rib fractures are visualized. Diffuse osteopenia of the thoracic spine with a mid thoracic and several lower thoracic XXXX deformities, age-indeterminate. There is an air-fluid level in the middle mediastinum, most XXXX secondary to a large hiatal hernia.",
"image_path": [
"CXR800_IM-2334/0.png",
"CXR800_IM-2334/1.png"
],
"split": "test"
},
{
"id": "CXR292_IM-1322",
"report": "The heart is normal in size and contour. There is a vague area of airspace disease identified within the right midlung on the PA view. This is not well-demonstrated on the lateral view. There is no pneumothorax or effusion.",
"image_path": [
"CXR292_IM-1322/0.png",
"CXR292_IM-1322/1.png"
],
"split": "test"
},
{
"id": "CXR3348_IM-1605",
"report": "Stable cardiomegaly. The lungs are clear. Stable left lung base calcifications. No focal consolidations. No pneumothorax or pleural effusions. The XXXX are intact.",
"image_path": [
"CXR3348_IM-1605/0.png",
"CXR3348_IM-1605/1.png"
],
"split": "test"
},
{
"id": "CXR608_IM-2196",
"report": "The heart and mediastinum are unremarkable. The lungs are clear without infiltrate. There is no effusion or pneumothorax. There is an old healed fracture through the right 8th rib.",
"image_path": [
"CXR608_IM-2196/0.png",
"CXR608_IM-2196/1.png"
],
"split": "test"
},
{
"id": "CXR862_IM-2383",
"report": "The parenchymal scar in the left lower lobe is unchanged in the interval. No XXXX infiltrates or masses in the lungs. Heart and mediastinum are normal.",
"image_path": [
"CXR862_IM-2383/0.png",
"CXR862_IM-2383/1.png"
],
"split": "test"
},
{
"id": "CXR30_IM-1385",
"report": "Lungs are clear without focal consolidation, effusion, or pneumothorax. Normal heart size. Negative for pneumoperitoneum. Bony thorax and soft tissue grossly unremarkable",
"image_path": [
"CXR30_IM-1385/0.png",
"CXR30_IM-1385/1.png"
],
"split": "test"
},
{
"id": "CXR3705_IM-1851-1001",
"report": "The lungs are clear. There is no pleural effusion or pneumothorax. There has been a XXXX XXXX sternotomy. The heart is not significantly enlarged. There are atherosclerotic changes of the aorta. Arthritic changes of the skeletal structures are noted.",
"image_path": [
"CXR3705_IM-1851-1001/0.png",
"CXR3705_IM-1851-1001/1.png"
],
"split": "test"
},
{
"id": "CXR2799_IM-1231",
"report": "Lungs are clear bilaterally. Cardiac and mediastinal silhouettes are normal. Pulmonary vasculature is normal. No pneumothorax or pleural effusion. No acute bony abnormality.",
"image_path": [
"CXR2799_IM-1231/0.png",
"CXR2799_IM-1231/1.png"
],
"split": "test"
},
{
"id": "CXR3682_IM-1834",
"report": "The lungs are hypoventilated. There is no focal airspace opacity. The cardiomediastinal silhouette is normal in size. There is no pneumothorax or large pleural effusion.",
"image_path": [
"CXR3682_IM-1834/0.png",
"CXR3682_IM-1834/1.png"
],
"split": "test"
},
{
"id": "CXR3388_IM-1633",
"report": "Normal heart size and mediastinal contours. Stable calcification in the left upper lobe, XXXX representing a granuloma. No focal airspace opacities. No pleural effusion or pneumothorax. Visualized osseous structures are unremarkable in appearance.",
"image_path": [
"CXR3388_IM-1633/0.png",
"CXR3388_IM-1633/1.png"
],
"split": "test"
},
{
"id": "CXR3523_IM-1721",
"report": "The heart and lungs have XXXX XXXX in the interval. Both lungs are clear and expanded. Heart and mediastinum normal. No change right anterior soft tissue surgical clips. Configuration of breast shadows on the PA view suggests prior right lumpectomy.",
"image_path": [
"CXR3523_IM-1721/0.png",
"CXR3523_IM-1721/1.png"
],
"split": "test"
},
{
"id": "CXR3657_IM-1818",
"report": "The heart size is normal. There is vascular congestion in bilateral hilar areas. The lungs are hyperexpanded with flattened diaphragms. No acute bony abnormalities. No effusion or infiltrate. No pneumothorax or pneumomediastinum.",
"image_path": [
"CXR3657_IM-1818/0.png",
"CXR3657_IM-1818/1.png"
],
"split": "test"
},
{
"id": "CXR3271_IM-1552",
"report": "The lungs are clear bilaterally. Specifically, no evidence of focal consolidation, pneumothorax, or pleural effusion.. Cardio mediastinal silhouette is unremarkable. Visualized osseous structures of the thorax are without acute abnormality.",
"image_path": [
"CXR3271_IM-1552/0.png",
"CXR3271_IM-1552/1.png"
],
"split": "test"
},
{
"id": "CXR1253_IM-0171-0001",
"report": "Heart size and pulmonary vascularity appear within normal limits. The lungs are free of focal airspace disease. No pleural effusion or pneumothorax is seen.",
"image_path": [
"CXR1253_IM-0171-0001/0.png",
"CXR1253_IM-0171-0001/1.png"
],
"split": "test"
},
{
"id": "CXR3359_IM-1612",
"report": "Heart size normal. No focal airspace disease. No pneumothorax or effusions.",
"image_path": [
"CXR3359_IM-1612/0.png",
"CXR3359_IM-1612/1.png"
],
"split": "test"
},
{
"id": "CXR2197_IM-0807",
"report": "Heart size is normal. There are XXXX opacities which appear to XXXX XXXX above the right XXXX fissure. There is mild thickening in the fissure. No pneumothorax. No large pleural effusions.",
"image_path": [
"CXR2197_IM-0807/0.png",
"CXR2197_IM-0807/1.png"
],
"split": "test"
},
{
"id": "CXR1953_IM-0621",
"report": "The lungs are clear without evidence of focal airspace disease. There is no evidence of pneumothorax or large pleural effusion. The cardiac and mediastinal contours are within normal limits. The XXXX are unremarkable.",
"image_path": [
"CXR1953_IM-0621/0.png",
"CXR1953_IM-0621/1.png"
],
"split": "test"
},
{
"id": "CXR3651_IM-1813",
"report": "Blunting of the costophrenic XXXX XXXX represents scarring. No pleural effusion is identified on the lateral view. There is no focal consolidation. No pneumothorax is present. The cardiomediastinal silhouette is within normal limits are in the pulmonary vasculature is normal.",
"image_path": [
"CXR3651_IM-1813/0.png",
"CXR3651_IM-1813/1.png"
],
"split": "test"
},
{
"id": "CXR700_IM-2265",
"report": "The heart is normal in size and contour. There is a calcified granuloma in the right lower lung. The lungs are clear, without evidence of infiltrate. There is no pneumothorax or effusion. Osteopenia with mild degenerative changes of the thoracic spine is noted.",
"image_path": [
"CXR700_IM-2265/0.png",
"CXR700_IM-2265/1.png"
],
"split": "test"
},
{
"id": "CXR3171_IM-1494",
"report": "The heart and lungs have XXXX XXXX in the interval. Both lungs are clear and expanded. Heart and mediastinum normal.",
"image_path": [
"CXR3171_IM-1494/0.png",
"CXR3171_IM-1494/1.png"
],
"split": "test"
},
{
"id": "CXR423_IM-2066-0001",
"report": "There is a left subphrenic crescentic lucency, this is concerning for pneumoperitoneum. There are low lung volumes and bilateral moderate to large pleural effusions with bibasilar atelectasis/airspace disease that are larger in size in comparison to the prior exam. No pneumothorax. Heart size upper limits of normal. The left central venous catheter tip overlies the lower SVC. The feeding tube has been placed in the interval and extends below the diaphragm and below the XXXX-of-view.",
"image_path": [
"CXR423_IM-2066-0001/0.png",
"CXR423_IM-2066-0001/1.png"
],
"split": "test"
},
{
"id": "CXR2081_IM-0713",
"report": "The lungs are well-expanded and clear. No pleural effusion or pneumothorax is seen. The cardiomediastinal contour is normal. No acute osseous lesions are identified.",
"image_path": [
"CXR2081_IM-0713/0.png",
"CXR2081_IM-0713/1.png"
],
"split": "test"
},
{
"id": "CXR1943_IM-0612",
"report": "Heart size normal. Mediastinum unremarkable. Pulmonary vascularity within normal limits. Lungs symmetrically aerated without focal infiltrate or consolidation. Multiple scattered calcified granulomas are present bilaterally. No focal volume loss evident. No pneumothorax or pleural effusion. Bony thorax unremarkable.",
"image_path": [
"CXR1943_IM-0612/0.png",
"CXR1943_IM-0612/1.png"
],
"split": "test"
},
{
"id": "CXR379_IM-1903",
"report": "There has been interval placement of a dual-lumen dialysis catheter with the distal tip projected over the right atrium. Moderate cardiomegaly is identified. There is mild calcification of the transverse XXXX. XXXX airspace opacities are identified with bilateral pleural effusions.",
"image_path": [
"CXR379_IM-1903/0.png",
"CXR379_IM-1903/1.png"
],
"split": "test"
},
{
"id": "CXR1586_IM-0380",
"report": "The cardiac silhouette mediastinal contours are within normal limits. The lungs are clear bilaterally. No focal opacities. There is no large pleural effusion. No pneumothorax. There is XXXX deformities involving multiple vertebral bodies of the thoracic spine which appear stable compared to the previous exam.",
"image_path": [
"CXR1586_IM-0380/0.png",
"CXR1586_IM-0380/1.png"
],
"split": "test"
},
{
"id": "CXR1965_IM-0629",
"report": "There is moderate cardiomegaly. There are bilateral interstitial opacities, increased since the previous exam. No focal airspace consolidation, pleural effusions or pneumothorax. No acute bony abnormalities.",
"image_path": [
"CXR1965_IM-0629/0.png",
"CXR1965_IM-0629/1.png"
],
"split": "test"
},
{
"id": "CXR759_IM-2309",
"report": "The lungs are clear. The cardiomediastinal silhouette is within normal limits. There is ectasia of the thoracic aorta. No pleural effusion is identified.",
"image_path": [
"CXR759_IM-2309/0.png",
"CXR759_IM-2309/1.png"
],
"split": "test"
},
{
"id": "CXR663_IM-2239",
"report": "Lungs are clear bilaterally with no focal infiltrate, pleural effusion, or pneumothoraces. Cardiomediastinal silhouette is within normal limits. No acute bony or soft tissue abnormality.",
"image_path": [
"CXR663_IM-2239/0.png",
"CXR663_IM-2239/1.png"
],
"split": "test"
},
{
"id": "CXR657_IM-2233-0001",
"report": "Heart is at the upper limits of normal size. Lungs are clear without focal infiltrates. No pneumothorax or pleural effusion. Normal pulmonary vascularity.",
"image_path": [
"CXR657_IM-2233-0001/0.png",
"CXR657_IM-2233-0001/1.png"
],
"split": "test"
},
{
"id": "CXR23_IM-0879",
"report": "The heart size and pulmonary vascularity appear within normal limits. The lungs are free of focal airspace disease. No pleural effusion or pneumothorax is seen.",
"image_path": [
"CXR23_IM-0879/0.png",
"CXR23_IM-0879/1.png"
],
"split": "test"
},
{
"id": "CXR1560_IM-0366",
"report": "Normal heart. Clear lungs. No pneumothorax. No pleural effusion.",
"image_path": [
"CXR1560_IM-0366/0.png",
"CXR1560_IM-0366/1.png"
],
"split": "test"
},
{
"id": "CXR353_IM-1726",
"report": "XXXX XXXX and lateral chest examination was obtained. There is improvement in bilateral pulmonary edema with mild residual. There is minimal right-sided pleural effusion. Heart silhouette is not enlarged. There is calcified mediastinal lymph XXXX. There is no pneumothorax",
"image_path": [
"CXR353_IM-1726/0.png",
"CXR353_IM-1726/1.png"
],
"split": "test"
},
{
"id": "CXR3860_IM-1954",
"report": "The heart size and mediastinal silhouette are within normal limits for contour. The lungs are clear. No pneumothorax or pleural effusions. The XXXX are intact.",
"image_path": [
"CXR3860_IM-1954/0.png",
"CXR3860_IM-1954/1.png"
],
"split": "test"
},
{
"id": "CXR3958_IM-2022",
"report": "Both lungs are clear and expanded. Heart and mediastinum normal.",
"image_path": [
"CXR3958_IM-2022/0.png",
"CXR3958_IM-2022/1.png"
],
"split": "test"
},
{
"id": "CXR3889_IM-1973",
"report": "Heart size is normal. No pneumothorax, pleural effusion, or focal airspace disease. Bony structures appear intact.",
"image_path": [
"CXR3889_IM-1973/0.png",
"CXR3889_IM-1973/1.png"
],
"split": "test"
},
{
"id": "CXR1539_IM-0349",
"report": "The lungs are clear. The cardiomediastinal silhouette is within normal limits. No pleural effusion is identified.",
"image_path": [
"CXR1539_IM-0349/0.png",
"CXR1539_IM-0349/1.png"
],
"split": "test"
},
{
"id": "CXR307_IM-1432",
"report": "The cardiomediastinal silhouette and pulmonary vasculature are within normal limits. There is no pneumothorax or pleural effusion. There are no focal areas of consolidation.",
"image_path": [
"CXR307_IM-1432/0.png",
"CXR307_IM-1432/1.png"
],
"split": "test"
},
{
"id": "CXR2285_IM-0870",
"report": "XXXX sternotomy XXXX and mediastinal postsurgical changes. Stable cardiomegaly. Crowded bronchovascular and interstitial markings XXXX related to low lung volumes and technique. Grossly stable appearance of the lungs compared to prior exam without overt edema or gross airspace consolidation.",
"image_path": [
"CXR2285_IM-0870/0.png",
"CXR2285_IM-0870/1.png"
],
"split": "test"
},
{
"id": "CXR3489_IM-1696",
"report": "The cardiomediastinal silhouette is normal in size and contour. No focal consolidation, pneumothorax or large pleural effusion. Normal XXXX.",
"image_path": [
"CXR3489_IM-1696/0.png",
"CXR3489_IM-1696/1.png"
],
"split": "test"
},
{
"id": "CXR2502_IM-1027-1001",
"report": "There is a focal area of opacity in the right midlung zone. This was not present on the recent prior study. There is prominence of the pulmonary markings throughout and there are small bilateral pleural effusions. The heart is not significantly enlarged. There is a prosthetic valve. There are atherosclerotic changes of the aorta. Arthritic changes of the skeletal structures are noted.",
"image_path": [
"CXR2502_IM-1027-1001/0.png",
"CXR2502_IM-1027-1001/1.png"
],
"split": "test"
},
{
"id": "CXR2000_IM-0654",
"report": "The heart is normal in size and contour. The lungs are clear, without evidence of infiltrate. There is no pneumothorax or effusion.",
"image_path": [
"CXR2000_IM-0654/0.png",
"CXR2000_IM-0654/1.png"
],
"split": "test"
},
{
"id": "CXR2082_IM-0714",
"report": "The heart is enlarged. There is pulmonary vascular congestion with diffusely increased interstitial and mild patchy airspace opacities. The distribution XXXX pulmonary edema. There is no pneumothorax or large pleural effusion. There are no acute bony findings.",
"image_path": [
"CXR2082_IM-0714/0.png",
"CXR2082_IM-0714/1.png"
],
"split": "test"
},
{
"id": "CXR1346_IM-0224",
"report": "There is a right chest XXXX with catheter tip at the cavoatrial junction. Heart size is at the upper limits of normal. Lungs are grossly clear. No pleural effusion or pneumothorax. There are diffuse degenerative changes of the spine.",
"image_path": [
"CXR1346_IM-0224/0.png",
"CXR1346_IM-0224/1.png"
],
"split": "test"
},
{
"id": "CXR1431_IM-0278",
"report": "The cardiomediastinal silhouette and pulmonary vasculature are within normal limits in size. The lungs are clear of focal airspace disease, pneumothorax, or pleural effusion. There are no acute bony findings.",
"image_path": [
"CXR1431_IM-0278/0.png",
"CXR1431_IM-0278/1.png"
],
"split": "test"
},
{
"id": "CXR3193_IM-1505",
"report": "Mild hyperinflation. No focal consolidation, suspicious pulmonary opacity, pneumothorax or definite pleural effusion. Heart size and pulmonary vascularity within normal limits, visualized osseous structures appear intact.",
"image_path": [
"CXR3193_IM-1505/0.png",
"CXR3193_IM-1505/1.png"
],
"split": "test"
},
{
"id": "CXR2743_IM-1197",
"report": "There are no acute osseous abnormalities. Degenerative changes throughout the thoracic spine. Normal heart size. Calcific aorta. Normal vascular markings. No focal area of consolidation, pleural effusion, or pneumothorax.",
"image_path": [
"CXR2743_IM-1197/0.png",
"CXR2743_IM-1197/1.png"
],
"split": "test"
},
{
"id": "CXR2179_IM-0791",
"report": "Flattening of the bilateral hemidiaphragms. Lungs are clear. Soft tissues and bony structures unremarkable. No pneumothorax or effusion.",
"image_path": [
"CXR2179_IM-0791/0.png",
"CXR2179_IM-0791/1.png"
],
"split": "test"
},
{
"id": "CXR2086_IM-0717",
"report": "The cardiomediastinal silhouette is within normal limits. Lungs are clear without focal consolidation. No visualized pneumothorax or large pleural effusion. No acute bone abnormality.",
"image_path": [
"CXR2086_IM-0717/0.png",
"CXR2086_IM-0717/1.png"
],
"split": "test"
},
{
"id": "CXR689_IM-2257",
"report": "Three noncalcified lung nodules are present in the left lower lobe. The largest measures 3.5 mm in diameter. Another nodule is present near the right hilum. It is approximately 2 cm in diameter. The XXXX and mediastinum appear normal. Heart size normal.",
"image_path": [
"CXR689_IM-2257/0.png",
"CXR689_IM-2257/1.png"
],
"split": "test"
},
{
"id": "CXR2552_IM-1058",
"report": "Lungs are clear without focal consolidation, effusion, or pneumothorax. Normal heart size. Bony thorax and soft tissues grossly unremarkable",
"image_path": [
"CXR2552_IM-1058/0.png",
"CXR2552_IM-1058/1.png"
],
"split": "test"
},
{
"id": "CXR2865_IM-1273",
"report": "The cardiomediastinal silhouette and pulmonary vasculature are within normal limits in size. The lungs are clear of focal airspace disease, pneumothorax, or pleural effusion. XXXX closure device demonstrated projecting over the right heart. There are no acute bony findings.",
"image_path": [
"CXR2865_IM-1273/0.png",
"CXR2865_IM-1273/1.png"
],
"split": "test"
},
{
"id": "CXR661_IM-2238",
"report": "Spinal stimulator in XXXX. Lungs are clear without focal airspace disease. No pleural effusions or pneumothoraces. Heart and mediastinum of normal size and contour. Degenerative changes in the thoracic spine.",
"image_path": [
"CXR661_IM-2238/0.png",
"CXR661_IM-2238/1.png"
],
"split": "test"
},
{
"id": "CXR3250_IM-1540-1001",
"report": "Lungs are relatively clear. Heart size normal. Unfolded aorta. Moderate hiatal hernia. T-spine osteophytes and DISH.",
"image_path": [
"CXR3250_IM-1540-1001/0.png",
"CXR3250_IM-1540-1001/1.png"
],
"split": "test"
},
{
"id": "CXR2706_IM-1172",
"report": "The lungs are clear. There is no pleural effusion. The heart and mediastinum are normal. Arthritic changes are seen throughout the spine and both XXXX.",
"image_path": [
"CXR2706_IM-1172/0.png",
"CXR2706_IM-1172/1.png"
],
"split": "test"
},
{
"id": "CXR1591_IM-0384",
"report": "The trachea is midline. The cardio mediastinal silhouette is of normal size and contour. No evidence of focal infiltrate or effusion. Low lung volumes XXXX XXXX atelectasis and bronchovascular crowding. There is no pneumothorax. The visualized bony structures reveal no acute abnormalities. Lateral view reveals degenerative changes of the thoracic spine.",
"image_path": [
"CXR1591_IM-0384/0.png",
"CXR1591_IM-0384/1.png"
],
"split": "test"
},
{
"id": "CXR1085_IM-0059",
"report": "The lungs demonstrate low lung volumes but are clear bilaterally. Specifically, no evidence of focal consolidation, pneumothorax, or pleural effusion.. Mild streaky opacities in the left upper lobe on frontal projection are XXXX atelectatic or scar. Cardio mediastinal silhouette is unremarkable. Visualized osseous structures of the thorax are without acute abnormality.",
"image_path": [
"CXR1085_IM-0059/0.png",
"CXR1085_IM-0059/1.png"
],
"split": "test"
},
{
"id": "CXR3672_IM-1828",
"report": "Stable appearance of aortic valve prosthesis. Sternotomy XXXX. Aortic calcifications. Mild interstitial edema. No focal infiltrate. No effusion or pneumothorax. Mild cardiomegaly.",
"image_path": [
"CXR3672_IM-1828/0.png",
"CXR3672_IM-1828/1.png"
],
"split": "test"
},
{
"id": "CXR3302_IM-1579",
"report": "The heart is normal in size. The mediastinum is unremarkable. The lungs are slightly hypoinflated but clear. There is no pleural effusion.",
"image_path": [
"CXR3302_IM-1579/0.png",
"CXR3302_IM-1579/1.png"
],
"split": "test"
},
{
"id": "CXR2631_IM-1118",
"report": "The cardiomediastinal silhouette is normal in size and contour. No focal consolidation, pneumothorax or large pleural effusion. Interval placement of right humeral prosthesis, incompletely evaluated. Incompletely evaluated the lumbar spine fusion XXXX. XXXX cholecystectomy.",
"image_path": [
"CXR2631_IM-1118/0.png",
"CXR2631_IM-1118/1.png"
],
"split": "test"
},
{
"id": "CXR491_IM-2111",
"report": "Cardiomediastinal silhouette is stable and within normal limits. There is improved lung volumes bilaterally with persistent bibasilar atelectatic opacities, without focal consolidation, pneumothorax, or effusion. No acute bony abnormality identified.",
"image_path": [
"CXR491_IM-2111/0.png",
"CXR491_IM-2111/1.png"
],
"split": "test"
},
{
"id": "CXR764_IM-2311",
"report": "The cardiomediastinal silhouette is normal in size and contour. No focal consolidation, pneumothorax or large pleural effusion. Negative for acute abnormality.",
"image_path": [
"CXR764_IM-2311/0.png",
"CXR764_IM-2311/1.png"
],
"split": "test"
},
{
"id": "CXR605_IM-2194",
"report": "The heart is normal in size. The mediastinum is unremarkable. Small nodular opacity left upper lobe may represent early infiltrate. The lungs are otherwise clear. There is no pleural effusion.",
"image_path": [
"CXR605_IM-2194/0.png",
"CXR605_IM-2194/1.png"
],
"split": "test"
},
{
"id": "CXR710_IM-2273",
"report": "Stable normal cardiac size and contour with unremarkable mediastinal silhouette. Normal pulmonary XXXX. No active airspace disease/infiltrate. No pleural effusion or pneumothorax. Calcified granuloma right upper lobe.",
"image_path": [
"CXR710_IM-2273/0.png",
"CXR710_IM-2273/1.png"
],
"split": "test"
},
{
"id": "CXR2618_IM-1107",
"report": "Normal cardiomediastinal contours. No pneumothorax or large pleural effusions. Small focal retrocardiac lung opacity.",
"image_path": [
"CXR2618_IM-1107/0.png",
"CXR2618_IM-1107/1.png"
],
"split": "test"
},
{
"id": "CXR3039_IM-1412",
"report": "Normal heart size. Clear lungs. No pneumothorax or large pleural effusion.",
"image_path": [
"CXR3039_IM-1412/0.png",
"CXR3039_IM-1412/1.png"
],
"split": "test"
},
{
"id": "CXR3721_IM-1859",
"report": "Streaky opacity is noted within the left lung base which may represent focal area of atelectasis. Right lung is grossly clear. Cardiac silhouette and mediastinal contours are within normal limits. There is no pneumothorax. No large pleural effusion.",
"image_path": [
"CXR3721_IM-1859/0.png",
"CXR3721_IM-1859/1.png"
],
"split": "test"
},
{
"id": "CXR1255_IM-0172-1001",
"report": "XXXX XXXX right-sided chest tube tip now projects outside the thoracic cavity. No definite residual pneumothorax. Stable cardiomediastinal silhouette. There are low lung volumes. No large pleural effusion. No focal airspace consolidation. Small amount of subdiaphragmatic free air.",
"image_path": [
"CXR1255_IM-0172-1001/0.png",
"CXR1255_IM-0172-1001/1.png"
],
"split": "test"
},
{
"id": "CXR2558_IM-1062",
"report": "There is no focal consolidation. There is no pneumothorax or large pleural effusion. The cardiomediastinal contours are grossly unremarkable. The heart size is within normal limits.",
"image_path": [
"CXR2558_IM-1062/0.png",
"CXR2558_IM-1062/1.png"
],
"split": "test"
},
{
"id": "CXR386_IM-1954",
"report": "Heart size within normal limits, stable mediastinal and hilar contours. No focal alveolar consolidation, no definite pleural effusion seen. Bronchovascular crowding without typical findings of pulmonary edema.",
"image_path": [
"CXR386_IM-1954/0.png",
"CXR386_IM-1954/1.png"
],
"split": "test"
},
{
"id": "CXR380_IM-1911",
"report": "The XXXX examination consists of supine and crosstable lateral radiographs of the chest. External monitor leads XXXX the thorax. The cardiomediastinal contours are within normal limits. Pulmonary vascularity is within normal limits. No focal consolidation, pleural effusion, or pneumothorax identified. The visualized osseous structures and upper abdomen are unremarkable.",
"image_path": [
"CXR380_IM-1911/0.png",
"CXR380_IM-1911/1.png"
],
"split": "test"
},
{
"id": "CXR1701_IM-0462",
"report": "Cardiac and mediastinal contours are within normal limits. The lungs are clear. Bony structures are intact.",
"image_path": [
"CXR1701_IM-0462/0.png",
"CXR1701_IM-0462/1.png"
],
"split": "test"
},
{
"id": "CXR3964_IM-2028",
"report": "The heart is normal in size. The mediastinum is unremarkable. The lungs are hyperinflated compatible with emphysema. There is biapical scarring. No acute infiltrate is seen.",
"image_path": [
"CXR3964_IM-2028/0.png",
"CXR3964_IM-2028/1.png"
],
"split": "test"
},
{
"id": "CXR238_IM-0939",
"report": "Stable cardiomediastinal silhouette. No focal pulmonary opacity, pleural effusion or pneumothorax. No acute bony abnormality.",
"image_path": [
"CXR238_IM-0939/0.png",
"CXR238_IM-0939/1.png"
],
"split": "test"
},
{
"id": "CXR2247_IM-0844",
"report": "The cardiomediastinal silhouette is normal in size and appearance. No pleural effusion or pneumothorax. Lungs are clear.",
"image_path": [
"CXR2247_IM-0844/0.png",
"CXR2247_IM-0844/1.png"
],
"split": "test"
},
{
"id": "CXR908_IM-2413",
"report": "The lungs appear clear. There are calcified nodules projecting in the right upper lung. Mediastinal contours appear normal. The heart pulmonary XXXX appear normal. Pleural spaces are clear. Surgical clips are identified in the right neck and left mediastinum.",
"image_path": [
"CXR908_IM-2413/0.png",
"CXR908_IM-2413/1.png"
],
"split": "test"
},
{
"id": "CXR3170_IM-1494",
"report": "Heart size is normal. Aorta is tortuous and ectatic. Cardiomediastinal contours are normal. Lungs are clear without evidence of fibrosis. Pleural effusions or pneumothorax. Endplate sclerotic changes are present in the thoracic spine.",
"image_path": [
"CXR3170_IM-1494/0.png",
"CXR3170_IM-1494/1.png"
],
"split": "test"
},
{
"id": "CXR768_IM-2313",
"report": "Normal heart size and mediastinal contours. No focal air space opacities. No pleural effusion. Visualized osseous structures are unremarkable.",
"image_path": [
"CXR768_IM-2313/0.png",
"CXR768_IM-2313/1.png"
],
"split": "test"
},
{
"id": "CXR3118_IM-1466",
"report": "No pneumothorax, pleural effusion, or focal airspace disease. Heart size normal. Cardiomediastinal silhouette stable. Nodular densities consistent with chronic granulomatous disease. Bony structures appear intact.",
"image_path": [
"CXR3118_IM-1466/0.png",
"CXR3118_IM-1466/1.png"
],
"split": "test"
},
{
"id": "CXR1738_IM-0486",
"report": "Cardiac and mediastinal contours are within normal limits. Mild aortic tortuosity. The lungs are clear. Bony structures are intact.",
"image_path": [
"CXR1738_IM-0486/0.png",
"CXR1738_IM-0486/1.png"
],
"split": "test"
},
{
"id": "CXR1109_IM-0076",
"report": "Heart size and mediastinal contours appear within normal limits. Pulmonary vascularity is within normal limits. No focal consolidation, suspicious pulmonary opacity, pneumothorax or definite pleural effusion. Visualized osseous structures appear intact.",
"image_path": [
"CXR1109_IM-0076/0.png",
"CXR1109_IM-0076/1.png"
],
"split": "test"
},
{
"id": "CXR968_IM-2458",
"report": "Heart size within normal limits. No focal alveolar consolidation, no definite pleural effusion seen. No typical findings of pulmonary edema. No pneumothorax.",
"image_path": [
"CXR968_IM-2458/0.png",
"CXR968_IM-2458/1.png"
],
"split": "test"
},
{
"id": "CXR1543_IM-0353",
"report": "The cardiomediastinal silhouette is within normal limits. The lungs are normally inflated without evidence of focal airspace disease, pleural effusion, or pneumothorax. No acute osseus abnormality. Large hiatal hernia.",
"image_path": [
"CXR1543_IM-0353/0.png",
"CXR1543_IM-0353/1.png"
],
"split": "test"
},
{
"id": "CXR1960_IM-0627",
"report": "Cardiac and mediastinal contours are within normal limits. The lungs are clear. Bony structures are intact.",
"image_path": [
"CXR1960_IM-0627/0.png",
"CXR1960_IM-0627/1.png"
],
"split": "test"
},
{
"id": "CXR937_IM-2433",
"report": "Normal cardiac size. Normal pulmonary vasculature. No airspace disease. Negative for pneumothorax. Negative for acute osseous deformity. The thoracic spine has a normal appearance.",
"image_path": [
"CXR937_IM-2433/0.png",
"CXR937_IM-2433/1.png"
],
"split": "test"
},
{
"id": "CXR912_IM-2417",
"report": "No focal consolidation. No visualized pneumothorax. No large pleural effusions. Heart size is normal. The cardiomediastinal silhouette is grossly unremarkable.",
"image_path": [
"CXR912_IM-2417/0.png",
"CXR912_IM-2417/1.png"
],
"split": "test"
},
{
"id": "CXR3509_IM-1711-0001",
"report": "The heart size and pulmonary vascularity appear within normal limits. Right pleural effusion is present and appears increased. No pneumothorax is identified. Some scattered XXXX of right base atelectasis are seen. Surgical XXXX remain in XXXX. The left lung appears clear.",
"image_path": [
"CXR3509_IM-1711-0001/0.png",
"CXR3509_IM-1711-0001/1.png"
],
"split": "test"
},
{
"id": "CXR2211_IM-0818",
"report": "There is persistent cardiomegaly with suggestion of left atrial enlargement as evidenced by cardiac contour the lateral image and XXXX density on the frontal image. The lungs are clear. No visible pleural effusion or pneumothorax.",
"image_path": [
"CXR2211_IM-0818/0.png",
"CXR2211_IM-0818/1.png"
],
"split": "test"
},
{
"id": "CXR1855_IM-0555",
"report": "Heart size within normal limits. There is focal left lateral base airspace disease. There is a 6 mm nodular opacity in the right midlung. No pneumothorax. No pleural effusion. No displaced rib fractures. There is an apparent deformity of the right humeral surgical neck. This is not seen on the comparison. Correlate clinically with history of fracture.",
"image_path": [
"CXR1855_IM-0555/0.png",
"CXR1855_IM-0555/1.png"
],
"split": "test"
},
{
"id": "CXR502_IM-2120",
"report": "Chest. The trachea is midline. Negative for pneumothorax, pleural effusion or focal airspace consolidation. The heart size is normal. Abdomen. No pneumoperitoneum. There is a normal bowel XXXX pattern. Air and stool visible throughout the entire large colon including the rectum. No abnormally dilated small bowel loops. No evidence for intussusception or small bowel obstruction. No pathologic calcifications XXXX over the abdomen or pelvis. XXXX XXXX are without fracture or destructive lesion, though there are mild degenerative changes throughout the lumbar spine. Small hiatal hernia is not as well demonstrated on this exam.",
"image_path": [
"CXR502_IM-2120/0.png",
"CXR502_IM-2120/1.png"
],
"split": "test"
},
{
"id": "CXR1623_IM-0405",
"report": "Normal cardiomediastinal contours. No pneumothorax, pleural effusions or focal lung consolidation.",
"image_path": [
"CXR1623_IM-0405/0.png",
"CXR1623_IM-0405/1.png"
],
"split": "test"
},
{
"id": "CXR1265_IM-0179",
"report": "Normal heart size. There is a round density in the AP XXXX. XXXX study performed in XXXX is not available for review at this time. Lungs are hyperinflated with flattened diaphragms. Calcified right lower lobe granuloma. No focal airspace consolidation, pneumothorax, or pleural effusion. No pulmonary edema. No acute bony abnormality.",
"image_path": [
"CXR1265_IM-0179/0.png",
"CXR1265_IM-0179/1.png"
],
"split": "test"
},
{
"id": "CXR1598_IM-0389",
"report": "Heart size, mediastinal contour, and pulmonary vascularity are within normal limits. No focal consolidation, pleural effusion, or pneumothorax is identified. No acute osseous abnormality identified.",
"image_path": [
"CXR1598_IM-0389/0.png",
"CXR1598_IM-0389/1.png"
],
"split": "test"
},
{
"id": "CXR2355_IM-0919",
"report": "PA and lateral views the chest were obtained. There are low lung volumes on the frontal view, which accentuates heart size and lung markings. The heart size is upper limits normal or mildly enlarged. Mediastinum normal width. The pulmonary vasculature is within normal limits. There is left lung base atelectasis on frontal XXXX XXXX secondary to low volumes. No pneumothorax, pleural effusion, or focal air space consolidation.",
"image_path": [
"CXR2355_IM-0919/0.png",
"CXR2355_IM-0919/1.png"
],
"split": "test"
},
{
"id": "CXR2290_IM-0874",
"report": "There are no focal areas of consolidation. No suspicious pulmonary opacities. Heart size within normal limits. No pleural effusions. No evidence of pneumothorax. Osseous structures are intact.",
"image_path": [
"CXR2290_IM-0874/0.png",
"CXR2290_IM-0874/1.png"
],
"split": "test"
},
{
"id": "CXR3505_IM-1707",
"report": "Heart size is normal and the lungs are clear.",
"image_path": [
"CXR3505_IM-1707/0.png",
"CXR3505_IM-1707/1.png"
],
"split": "test"
},
{
"id": "CXR2760_IM-1207",
"report": "There is minimal scarring within the left lung base. The lungs are otherwise clear. Heart size is normal. No pneumothorax.",
"image_path": [
"CXR2760_IM-1207/0.png",
"CXR2760_IM-1207/1.png"
],
"split": "test"
},
{
"id": "CXR3534_IM-1727",
"report": "Lungs are clear bilaterally. There is no focal consolidation, pleural effusion, or pneumothoraces. Heart size is normal. Stable right paratracheal prominence, consistent with known calcified lymph node, seen on prior CT chest dated XXXX. XXXX are unremarkable.",
"image_path": [
"CXR3534_IM-1727/0.png",
"CXR3534_IM-1727/1.png"
],
"split": "test"
},
{
"id": "CXR2577_IM-1077",
"report": "Cardiomediastinal silhouette within normal limits. No acute bony abnormality. There are XXXX XXXX opacities, atelectasis versus airspace disease. No large effusion or pneumothorax.",
"image_path": [
"CXR2577_IM-1077/0.png",
"CXR2577_IM-1077/1.png"
],
"split": "test"
},
{
"id": "CXR1110_IM-0076",
"report": "Cardiomediastinal contours within normal limits. Pulmonary vascularity is normal. There are scattered calcified testes bilaterally, consistent with prior granulomatous infection, stable. No XXXX focal airspace consolidation. No pleural effusion, no pneumothorax. Bony structures unremarkable.",
"image_path": [
"CXR1110_IM-0076/0.png",
"CXR1110_IM-0076/1.png"
],
"split": "test"
},
{
"id": "CXR3083_IM-1442",
"report": "The lungs and pleural spaces show no acute abnormality. Heart size and pulmonary vascularity within normal limits. .",
"image_path": [
"CXR3083_IM-1442/0.png",
"CXR3083_IM-1442/1.png"
],
"split": "test"
},
{
"id": "CXR1130_IM-0087",
"report": "Heart size and pulmonary vascularity appear within normal limits. Calcified granuloma is present in the right base. No pneumothorax or pleural effusion is seen. In the lateral right base is identified an ill-defined somewhat oblong opacity. This was not present on the previous study. The remainder of the lungs appear clear.",
"image_path": [
"CXR1130_IM-0087/0.png",
"CXR1130_IM-0087/1.png"
],
"split": "test"
},
{
"id": "CXR3582_IM-1761",
"report": "Heart size is normal. The lungs are clear. There is no pneumothorax or large pleural effusion.",
"image_path": [
"CXR3582_IM-1761/0.png",
"CXR3582_IM-1761/1.png"
],
"split": "test"
},
{
"id": "CXR613_IM-2200",
"report": "The heart and lungs have XXXX XXXX in the interval. Both lungs are clear and expanded. Heart and mediastinum normal.",
"image_path": [
"CXR613_IM-2200/0.png",
"CXR613_IM-2200/1.png"
],
"split": "test"
},
{
"id": "CXR591_IM-2186",
"report": "The cardiomediastinal silhouette is within normal limits. The lungs are clear without areas of focal consolidation. There is a calcified granuloma within the left lung base. There is suggestion of a deep sulcus sign on the right. No definite pleural line of pneumothorax visualized. There is age-indeterminate wedging of several midthoracic vertebral bodies.",
"image_path": [
"CXR591_IM-2186/0.png",
"CXR591_IM-2186/1.png"
],
"split": "test"
},
{
"id": "CXR2077_IM-0710",
"report": "Right jugular XXXX catheter present with tip overlying the lower SVC. Curvilinear density projecting over the upper chest appears external on the lateral projection. Correlate clinically. Normal heart size and mediastinal contour appear normal pulmonary vascularity. XXXX scar/subsegmental atelectasis in the lingula. No focal airspace consolidation, pleural effusion, or pneumothorax. No acute osseous findings. Mild degenerative changes of the spine.",
"image_path": [
"CXR2077_IM-0710/0.png",
"CXR2077_IM-0710/1.png"
],
"split": "test"
},
{
"id": "CXR1788_IM-0513",
"report": "The trachea is midline. Negative for pneumothorax, pleural effusion, or focal airspace consolidation. The heart size is normal.",
"image_path": [
"CXR1788_IM-0513/0.png",
"CXR1788_IM-0513/1.png"
],
"split": "test"
},
{
"id": "CXR3981_IM-2039",
"report": "The lungs are clear. There is no pleural effusion or pneumothorax. The heart and mediastinum are normal. The skeletal structures are normal.",
"image_path": [
"CXR3981_IM-2039/0.png",
"CXR3981_IM-2039/1.png"
],
"split": "test"
},
{
"id": "CXR2100_IM-0731",
"report": "The heart size and mediastinal contours appear within normal limits. Atherosclerotic calcification of the aorta. No focal airspace consolidation, pleural effusions or pneumothorax. Questionable thin-walled cavitary lesion in the right lower lobe, only seen on the AP view and may represent artifact. No acute bony abnormalities.",
"image_path": [
"CXR2100_IM-0731/0.png",
"CXR2100_IM-0731/1.png"
],
"split": "test"
},
{
"id": "CXR3282_IM-1563",
"report": "Low lung volumes bilaterally, with lungs otherwise grossly clear. No focal consolidation, pneumothorax, or large pleural effusion. The cardiomediastinal silhouette is unremarkable. No acute osseous abnormalities identified.",
"image_path": [
"CXR3282_IM-1563/0.png",
"CXR3282_IM-1563/1.png"
],
"split": "test"
},
{
"id": "CXR3321_IM-1588",
"report": "XXXX XXXX and lateral chest examination was obtained. The heart silhouette is normal in size and contour. Aortic XXXX appear unremarkable. Lungs demonstrate no acute findings. There is no effusion or pneumothorax.",
"image_path": [
"CXR3321_IM-1588/0.png",
"CXR3321_IM-1588/1.png"
],
"split": "test"
},
{
"id": "CXR670_IM-2244",
"report": "The heart is top normal in size. The mediastinum is Stable. The aorta is atherosclerotic. There are mild chronic changes without focal consolidation. No pleural effusion is seen.",
"image_path": [
"CXR670_IM-2244/0.png",
"CXR670_IM-2244/1.png"
],
"split": "test"
},
{
"id": "CXR2660_IM-1142",
"report": "Heart size normal. Lungs are clear. XXXX are normal. No pneumonia, effusions, edema, pneumothorax, adenopathy, nodules or masses.",
"image_path": [
"CXR2660_IM-1142/0.png",
"CXR2660_IM-1142/1.png"
],
"split": "test"
},
{
"id": "CXR3933_IM-2004",
"report": "The heart size is normal. No pneumothorax. No large pleural effusions. No focal airspace opacities.",
"image_path": [
"CXR3933_IM-2004/0.png",
"CXR3933_IM-2004/1.png"
],
"split": "test"
},
{
"id": "CXR1282_IM-0188",
"report": "Normal heart size and mediastinal contours. Patchy right lower lobe airspace opacities. No pleural effusion or pneumothorax. Visualized osseous structures are unremarkable in appearance.",
"image_path": [
"CXR1282_IM-0188/0.png",
"CXR1282_IM-0188/1.png"
],
"split": "test"
},
{
"id": "CXR3360_IM-1613",
"report": "The lungs are clear bilaterally. Specifically, no evidence of focal consolidation, pneumothorax, or pleural effusion.. Left basilar subsegmental atelectasis versus scar noted. Cardio mediastinal silhouette is unremarkable. Visualized osseous structures of the thorax are without acute abnormality.",
"image_path": [
"CXR3360_IM-1613/0.png",
"CXR3360_IM-1613/1.png"
],
"split": "test"
},
{
"id": "CXR1517_IM-0335",
"report": "The lungs are clear bilaterally. Specifically, no evidence of focal consolidation, pneumothorax, or pleural effusion.. Cardio mediastinal silhouette is unremarkable. Visualized osseous structures of the thorax are without acute abnormality.",
"image_path": [
"CXR1517_IM-0335/0.png",
"CXR1517_IM-0335/1.png"
],
"split": "test"
},
{
"id": "CXR367_IM-1826",
"report": "The lungs are clear. No focal airspace consolidation. No pleural effusion or pneumothorax. Heart size is within normal limits.",
"image_path": [
"CXR367_IM-1826/0.png",
"CXR367_IM-1826/1.png"
],
"split": "test"
},
{
"id": "CXR3653_IM-1815",
"report": "The XXXX examination consists of frontal and lateral radiographs of the chest. There are diminished lung volumes with XXXX XXXX atelectasis. The cardiac silhouette is unchanged. There is mild to moderate tortuosity of the thoracic aorta. No focal consolidation, pleural effusion, or pneumothorax identified. Thoracic spondylosis is again seen.",
"image_path": [
"CXR3653_IM-1815/0.png",
"CXR3653_IM-1815/1.png"
],
"split": "test"
},
{
"id": "CXR1911_IM-0593",
"report": "Cardiac and mediastinal contours are unremarkable. Pulmonary vascularity is within normal limits. No focal air space opacities, pleural effusion, or pneumothorax. XXXX are grossly unremarkable.",
"image_path": [
"CXR1911_IM-0593/0.png",
"CXR1911_IM-0593/1.png"
],
"split": "test"
},
{
"id": "CXR1117_IM-0079",
"report": "The cardiomediastinal silhouette and pulmonary vasculature are within normal limits in size. There is ill-defined airspace opacity in the posterior left lower lobe. There is focal opacity in the right upper lobe which suggests scar and/or granulomatous calcification. There is no pneumothorax or pleural effusion.",
"image_path": [
"CXR1117_IM-0079/0.png",
"CXR1117_IM-0079/1.png"
],
"split": "test"
},
{
"id": "CXR3576_IM-1757",
"report": "The cardiomediastinal silhouette is within normal limits. The lungs are clear without areas of focal consolidation. No pneumothorax or large pleural effusion. No acute bone abnormality.",
"image_path": [
"CXR3576_IM-1757/0.png",
"CXR3576_IM-1757/1.png"
],
"split": "test"
},
{
"id": "CXR2008_IM-0658",
"report": "No focal consolidation. No visualized pneumothorax. No pleural effusions. Heart size normal. The cardiomediastinal silhouette is unremarkable.",
"image_path": [
"CXR2008_IM-0658/0.png",
"CXR2008_IM-0658/1.png"
],
"split": "test"
},
{
"id": "CXR3746_IM-1872",
"report": "Compared to prior examination, XXXX stent has been removed. Cardiomediastinal silhouette is stable and within normal limits. Stable mild atherosclerotic calcifications of the aortic XXXX are noted. There are mildly low lung volumes without focal consolidation, pneumothorax, or effusion identified. No acute bony abnormality seen.",
"image_path": [
"CXR3746_IM-1872/0.png",
"CXR3746_IM-1872/1.png"
],
"split": "test"
},
{
"id": "CXR3975_IM-2035",
"report": "No focal consolidation. No visualized pneumothorax. No large pleural effusions. Heart size normal. Cardiomediastinal silhouette is unremarkable.",
"image_path": [
"CXR3975_IM-2035/0.png",
"CXR3975_IM-2035/1.png"
],
"split": "test"
},
{
"id": "CXR1280_IM-0187",
"report": "The cardiac silhouette and mediastinum size are within normal limits. There is no pulmonary edema. There is no focal consolidation. There are no XXXX of pleural effusion. There is no evidence of pneumothorax.",
"image_path": [
"CXR1280_IM-0187/0.png",
"CXR1280_IM-0187/1.png"
],
"split": "test"
},
{
"id": "CXR3426_IM-1656",
"report": "The heart, pulmonary XXXX and mediastinum are within normal limits. There is no pleural effusion or pneumothorax. There is no focal air space opacity to suggest a pneumonia. There are minimal degenerative changes of the spine.",
"image_path": [
"CXR3426_IM-1656/0.png",
"CXR3426_IM-1656/1.png"
],
"split": "test"
},
{
"id": "CXR1466_IM-0302",
"report": "The heart is normal size. The mediastinum is unremarkable. There is no pleural effusion, pneumothorax, or focal airspace disease. The XXXX are unremarkable.",
"image_path": [
"CXR1466_IM-0302/0.png",
"CXR1466_IM-0302/1.png"
],
"split": "test"
},
{
"id": "CXR3722_IM-1859",
"report": "The lungs are clear. Heart size is normal. No pneumothorax.",
"image_path": [
"CXR3722_IM-1859/0.png",
"CXR3722_IM-1859/1.png"
],
"split": "test"
},
{
"id": "CXR1574_IM-0374",
"report": "Lungs are clear bilaterally. Cardiac and mediastinal silhouettes are normal. Pulmonary vasculature is normal. No pneumothorax or pleural effusion. No acute bony abnormality.",
"image_path": [
"CXR1574_IM-0374/0.png",
"CXR1574_IM-0374/1.png"
],
"split": "test"
},
{
"id": "CXR2695_IM-1166",
"report": "The cardiac contours are normal. The lungs are hyperinflated with flattened diaphragms. No acute pulmonary findings. Thoracic spondylosis.",
"image_path": [
"CXR2695_IM-1166/0.png",
"CXR2695_IM-1166/1.png"
],
"split": "test"
},
{
"id": "CXR1175_IM-0119",
"report": "Both lungs are clear and expanded. Heart and mediastinum normal.",
"image_path": [
"CXR1175_IM-0119/0.png",
"CXR1175_IM-0119/1.png"
],
"split": "test"
},
{
"id": "CXR814_IM-2345",
"report": "There is a calcified granuloma in the lateral left base. There is no pleural effusion or pneumothorax. The heart is not significantly enlarged. There are calcified left hilar lymph XXXX. There are atherosclerotic changes of the aorta. Arthritic changes of the skeletal structures are noted as well as scoliosis and lumbar region.",
"image_path": [
"CXR814_IM-2345/0.png",
"CXR814_IM-2345/1.png"
],
"split": "test"
},
{
"id": "CXR442_IM-2078",
"report": "The lungs remain hyperexpanded. No XXXX infiltrates or masses. Heart and mediastinum are normal.",
"image_path": [
"CXR442_IM-2078/0.png",
"CXR442_IM-2078/1.png"
],
"split": "test"
},
{
"id": "CXR1133_IM-0090",
"report": "Lungs are hyperexpanded. No infiltrates or masses. The eventration of the left hemidiaphragm identified previously is largely unchanged since the previous computed tomogram. Pulmonary XXXX are normal.",
"image_path": [
"CXR1133_IM-0090/0.png",
"CXR1133_IM-0090/1.png"
],
"split": "test"
},
{
"id": "CXR1601_IM-0390",
"report": "The lungs and pleural spaces show no acute abnormality. Heart size and pulmonary vascularity within normal limits.",
"image_path": [
"CXR1601_IM-0390/0.png",
"CXR1601_IM-0390/1.png"
],
"split": "test"
},
{
"id": "CXR3810_IM-1920",
"report": "The heart and mediastinum are unremarkable. The lungs are clear without infiltrate. There is no effusion or pneumothorax. There is surgical clips projected over the left lung apex, as well as, over the right upper quadrant of the abdomen.",
"image_path": [
"CXR3810_IM-1920/0.png",
"CXR3810_IM-1920/1.png"
],
"split": "test"
},
{
"id": "CXR1683_IM-0449",
"report": "The XXXX examination consists of frontal and lateral radiographs of the chest. There are diminished lung volumes. Right greater than left bilateral hilar and subcarinal adenopathy is again seen. The cardiac silhouette is prominent but probably artifactually large due to diminished lung volumes. No focal consolidation, pleural effusion, or pneumothorax identified. There is a deformity of the left clavicle compatible with remote XXXX.",
"image_path": [
"CXR1683_IM-0449/0.png",
"CXR1683_IM-0449/1.png"
],
"split": "test"
},
{
"id": "CXR859_IM-2380",
"report": "The cardiomediastinal silhouette and vasculature are within normal limits for size and contour. XXXX right lower lung opacity XXXX represents combination of soft tissue overlay and minimal atelectasis. No focal airspace consolidation, pleural effusion, or pneumothorax. Osseous structures are within normal limits for patient age.",
"image_path": [
"CXR859_IM-2380/0.png",
"CXR859_IM-2380/1.png"
],
"split": "test"
},
{
"id": "CXR2210_IM-0817",
"report": "The cardiomediastinal silhouette is within normal limits for appearance. No focal areas of pulmonary consolidation. No pneumothorax. No pleural effusion. The thoracic spine appears intact..",
"image_path": [
"CXR2210_IM-0817/0.png",
"CXR2210_IM-0817/1.png"
],
"split": "test"
},
{
"id": "CXR1094_IM-0065",
"report": "No acute osseous abnormality. The soft tissues are within normal limits. Normal appearing cardiomediastinal silhouette and hilar contours. Left lower lobe XXXX density XXXX representing atelectasis. No focal area of consolidation, pleural effusion, pneumothorax.",
"image_path": [
"CXR1094_IM-0065/0.png",
"CXR1094_IM-0065/1.png"
],
"split": "test"
},
{
"id": "CXR539_IM-2145",
"report": "2 images. Heart size and pulmonary vascular engorgement appear within limits of normal. Mediastinal contour is unremarkable. No focal consolidation, pleural effusion, or pneumothorax identified. No convincing acute bony findings.",
"image_path": [
"CXR539_IM-2145/0.png",
"CXR539_IM-2145/1.png"
],
"split": "test"
},
{
"id": "CXR1964_IM-0629",
"report": "Heart size and mediastinal contours appear within normal limits. Pulmonary vascularity is within normal limits. No focal consolidation, suspicious pulmonary opacity, pneumothorax or definite pleural effusion. Visualized osseous structures appear intact.",
"image_path": [
"CXR1964_IM-0629/0.png",
"CXR1964_IM-0629/1.png"
],
"split": "test"
},
{
"id": "CXR1158_IM-0107",
"report": "Heart size remains slightly large. Aorta remains tortuous. Pulmonary XXXX remain normal. No infiltrates or masses in the lungs.",
"image_path": [
"CXR1158_IM-0107/0.png",
"CXR1158_IM-0107/1.png"
],
"split": "test"
},
{
"id": "CXR2275_IM-0862",
"report": "The cardiomediastinal silhouette is within normal limits for size and contour. There is a right middle lobe nodule which is denser than adjacent XXXX is most XXXX calcified. The lungs are normally inflated without evidence of focal airspace disease, pleural effusion, or pneumothorax. Degenerative endplate changes of the spine.",
"image_path": [
"CXR2275_IM-0862/0.png",
"CXR2275_IM-0862/1.png"
],
"split": "test"
},
{
"id": "CXR511_IM-2127",
"report": "Hyperaerated lungs with flattened hemidiaphragms. Normal heart size. Increased retrosternal airspace. No focal infiltrate. No pneumothorax or pleural effusion.",
"image_path": [
"CXR511_IM-2127/0.png",
"CXR511_IM-2127/1.png"
],
"split": "test"
},
{
"id": "CXR399_IM-2043",
"report": "Heart size and pulmonary vascularity appear within normal limits. The lungs are free of focal airspace disease. No pleural effusion or pneumothorax is seen. Degenerative changes are present in the spine.",
"image_path": [
"CXR399_IM-2043/0.png",
"CXR399_IM-2043/1.png"
],
"split": "test"
},
{
"id": "CXR301_IM-1389",
"report": "Normal cardiomediastinal contours. Clear lungs bilaterally. No pneumothorax or large effusion.",
"image_path": [
"CXR301_IM-1389/0.png",
"CXR301_IM-1389/1.png"
],
"split": "test"
},
{
"id": "CXR391_IM-1986",
"report": "Low lung volumes. Heart size normal. No focal airspace consolidations. No pneumothorax or effusions.",
"image_path": [
"CXR391_IM-1986/0.png",
"CXR391_IM-1986/1.png"
],
"split": "test"
},
{
"id": "CXR3378_IM-1627",
"report": "There is a moderate right-sided pneumothorax measuring approximately 3.3 cm in the right apex. There is a minimally displaced right lateral 8th rib fracture and probable nondisplaced right lateral 7th rib fracture. Cardiomediastinal silhouette is within normal limits. Left lung is clear.",
"image_path": [
"CXR3378_IM-1627/0.png",
"CXR3378_IM-1627/1.png"
],
"split": "test"
},
{
"id": "CXR760_IM-2310",
"report": "There is minimal hyperexpansion and hyperlucency of the lungs suggestive of chronic lung disease, without focal consolidation, pneumothorax, or effusion identified. XXXX opacity in the left XXXX XXXX subsegmental atelectasis. Cardiomediastinal silhouette is grossly stable and within normal limits, with mild tortuosity and atherosclerosis of the thoracic aorta. Multilevel degenerative disc disease of the thoracolumbar spine noted without acute bony abnormality.",
"image_path": [
"CXR760_IM-2310/0.png",
"CXR760_IM-2310/1.png"
],
"split": "test"
},
{
"id": "CXR3814_IM-1923",
"report": "No focal consolidation, pneumothorax or definite pleural effusion. Heart size within normal limits, no mediastinal widening characteristic in appearance of vascular injury. No acute osseous injury XXXX demonstrated.",
"image_path": [
"CXR3814_IM-1923/0.png",
"CXR3814_IM-1923/1.png"
],
"split": "test"
},
{
"id": "CXR3224_IM-1524",
"report": "The cardiomediastinal silhouette is normal in size and contour. No focal consolidation, pneumothorax or large pleural effusion. Negative for acute bone abnormality.",
"image_path": [
"CXR3224_IM-1524/0.png",
"CXR3224_IM-1524/1.png"
],
"split": "test"
},
{
"id": "CXR929_IM-2427",
"report": "No change lung XXXX. XXXX opacities are present in the right lower lobe. No focal infiltrates. Heart and mediastinum are unremarkable. Aorta normal.",
"image_path": [
"CXR929_IM-2427/0.png",
"CXR929_IM-2427/1.png"
],
"split": "test"
},
{
"id": "CXR1697_IM-0458",
"report": "Lungs are clear bilaterally. Cardiac and mediastinal silhouettes are normal. Pulmonary vasculature is normal. No pneumothorax or pleural effusion. No acute bony abnormality.",
"image_path": [
"CXR1697_IM-0458/0.png",
"CXR1697_IM-0458/1.png"
],
"split": "test"
},
{
"id": "CXR2200_IM-0811",
"report": "Low lung volumes. Bibasilar atelectasis versus scarring. Stable left abdominal surgical clips. The heart size and mediastinal silhouette are within normal limits for contour. No pneumothorax or pleural effusions. The XXXX are intact.",
"image_path": [
"CXR2200_IM-0811/0.png",
"CXR2200_IM-0811/1.png"
],
"split": "test"
},
{
"id": "CXR3594_IM-1772",
"report": "The cardiomediastinal silhouette is normal. No focal airspace consolidation. No pneumothorax or pleural effusion.",
"image_path": [
"CXR3594_IM-1772/0.png",
"CXR3594_IM-1772/1.png"
],
"split": "test"
},
{
"id": "CXR2579_IM-1078",
"report": "The lungs are clear without focal consolidation, effusion, or pneumothorax. Normal heart size. Bony thorax unremarkable.",
"image_path": [
"CXR2579_IM-1078/0.png",
"CXR2579_IM-1078/1.png"
],
"split": "test"
},
{
"id": "CXR3836_IM-1939",
"report": "The heart size is normal. The mediastinal contour is within normal limits. The lungs are free of any focal infiltrates. There are no nodules or masses. No visible pneumothorax. No visible pleural fluid. The XXXX are grossly normal. There is no visible free intraperitoneal air under the diaphragm.",
"image_path": [
"CXR3836_IM-1939/0.png",
"CXR3836_IM-1939/1.png"
],
"split": "test"
},
{
"id": "CXR3428_IM-1657",
"report": "There is a prominent calcified head to the right anterior first rib. The aorta is tortuous. There are T-spine osteophytes. The cardiomediastinal silhouette and pulmonary vasculature are within normal limits. There is no pneumothorax or pleural effusion. There are no focal areas of consolidation.",
"image_path": [
"CXR3428_IM-1657/0.png",
"CXR3428_IM-1657/1.png"
],
"split": "test"
},
{
"id": "CXR1226_IM-0150",
"report": "The heart size is within normal limits. Trachea is midline. No pleural effusions or pneumothorax. Cardiomediastinal contours are normal. There is focal consolidation in the posterior segment of the right lower lobe. No bony or soft tissue abnormalities.",
"image_path": [
"CXR1226_IM-0150/0.png",
"CXR1226_IM-0150/1.png"
],
"split": "test"
},
{
"id": "CXR419_IM-2062",
"report": "Cardiac and mediastinal contours are within normal limits. The lungs are clear. Bony structures are intact.",
"image_path": [
"CXR419_IM-2062/0.png",
"CXR419_IM-2062/1.png"
],
"split": "test"
},
{
"id": "CXR3196_IM-1507",
"report": "Both lungs are clear and expanded. Heart and mediastinum normal.",
"image_path": [
"CXR3196_IM-1507/0.png",
"CXR3196_IM-1507/1.png"
],
"split": "test"
},
{
"id": "CXR3976_IM-2035",
"report": "Heart size and mediastinal contour are normal. Pulmonary vascularity is normal. Lungs are clear. No pleural effusions or pneumothoraces.",
"image_path": [
"CXR3976_IM-2035/0.png",
"CXR3976_IM-2035/1.png"
],
"split": "test"
},
{
"id": "CXR3081_IM-1440",
"report": "The heart is normal in size. The aorta is tortuous and ectatic. The lungs are clear without focal airspace opacity, pleural effusion, or pneumothorax. The osseous structures are intact.",
"image_path": [
"CXR3081_IM-1440/0.png",
"CXR3081_IM-1440/1.png"
],
"split": "test"
},
{
"id": "CXR1302_IM-0198",
"report": "Lungs are clear. No pleural effusions or pneumothoraces. heart and mediastinum are stable with ectasia of the aorta. Heart size is upper limits of normal. Degenerative changes in the spine.",
"image_path": [
"CXR1302_IM-0198/0.png",
"CXR1302_IM-0198/1.png"
],
"split": "test"
},
{
"id": "CXR3639_IM-1804",
"report": "The cardiac and mediastinal silhouette is normal There is no evidence of pneumomediastinum or pneumothorax. Clear lungs There are no large pleural effusions No evidence of displaced fractures.",
"image_path": [
"CXR3639_IM-1804/0.png",
"CXR3639_IM-1804/1.png"
],
"split": "test"
},
{
"id": "CXR1249_IM-0169",
"report": "The lungs are clear without evidence of focal airspace disease. There are calcified granulomas in the left lower lobe. There is no evidence of pneumothorax or large pleural effusion. The cardiac and mediastinal contours are within normal limits. The XXXX are unremarkable.",
"image_path": [
"CXR1249_IM-0169/0.png",
"CXR1249_IM-0169/1.png"
],
"split": "test"
},
{
"id": "CXR190_IM-0583",
"report": "The heart is normal in size. The mediastinum is unremarkable. The lungs are clear. There is no obvious lytic or destructive lesion. No displaced rib fracture is evident.",
"image_path": [
"CXR190_IM-0583/0.png",
"CXR190_IM-0583/1.png"
],
"split": "test"
},
{
"id": "CXR2151_IM-0771",
"report": "Hyperinflated lungs with flattened diaphragm and increased retrosternal airspace. No focal alveolar consolidation, no definite pleural effusion seen. Heart size within normal limits, the typical findings of pulmonary edema. Mild spine dextrocurvature noted.",
"image_path": [
"CXR2151_IM-0771/0.png",
"CXR2151_IM-0771/1.png"
],
"split": "test"
},
{
"id": "CXR1920_IM-0598",
"report": "Cardiomediastinal silhouette is normal in size and contour. Pulmonary vasculature is normal in caliber. Lungs are clear of focal airspace disease, pneumothorax or pleural effusion. There are no acute bony findings.",
"image_path": [
"CXR1920_IM-0598/0.png",
"CXR1920_IM-0598/1.png"
],
"split": "test"
},
{
"id": "CXR3112_IM-1461",
"report": "The heart is normal in size. The mediastinum is unremarkable. The lungs are clear.",
"image_path": [
"CXR3112_IM-1461/0.png",
"CXR3112_IM-1461/1.png"
],
"split": "test"
},
{
"id": "CXR2291_IM-0874",
"report": "Heart size is normal. The lungs are clear. There are no focal air space consolidations. No pleural effusions or pneumothoraces. The hilar and mediastinal contours are normal. Normal pulmonary vascularity. Umbilical piercing.",
"image_path": [
"CXR2291_IM-0874/0.png",
"CXR2291_IM-0874/1.png"
],
"split": "test"
},
{
"id": "CXR1610_IM-0395",
"report": "The heart and lungs have XXXX XXXX in the interval. Both lungs are clear and expanded. Heart and mediastinum normal.",
"image_path": [
"CXR1610_IM-0395/0.png",
"CXR1610_IM-0395/1.png"
],
"split": "test"
},
{
"id": "CXR1017_IM-0013",
"report": "Both lungs are clear and expanded with no infiltrates. Basilar focal atelectasis is present in the lingula. Heart size normal. Calcified right hilar XXXX are present",
"image_path": [
"CXR1017_IM-0013/0.png",
"CXR1017_IM-0013/1.png"
],
"split": "test"
},
{
"id": "CXR1234_IM-0157",
"report": "2 images. The cardiac silhouette is enlarged. Thoracic aortic atherosclerotic calcifications are present. There are finding status post sternotomy and CABG. XXXX atelectasis or scar is noted within the left midlung. There is blunting of the left costophrenic XXXX. No pneumothorax.",
"image_path": [
"CXR1234_IM-0157/0.png",
"CXR1234_IM-0157/1.png"
],
"split": "test"
},
{
"id": "CXR3785_IM-1898",
"report": "No pneumothorax or large pleural effusion. Mildly prominent perihilar opacities, XXXX due to bronchovascular crowding. Heart size within normal limits. Cardiomediastinal silhouette is XXXX. The bony structures appear intact.",
"image_path": [
"CXR3785_IM-1898/0.png",
"CXR3785_IM-1898/1.png"
],
"split": "test"
},
{
"id": "CXR510_IM-2126",
"report": "Lungs are clear bilaterally with no focal infiltrate, pleural effusion, or pneumothoraces. Cardiomediastinal silhouette is within normal limits. XXXX and soft tissues are unremarkable.",
"image_path": [
"CXR510_IM-2126/0.png",
"CXR510_IM-2126/1.png"
],
"split": "test"
},
{
"id": "CXR1972_IM-0633",
"report": "There is a XXXX airspace opacity in the left upper lung. Heart size within normal limits. Mild calcification of the aortic XXXX. No pneumothorax or pleural effusions.",
"image_path": [
"CXR1972_IM-0633/0.png",
"CXR1972_IM-0633/1.png"
],
"split": "test"
},
{
"id": "CXR1515_IM-0333",
"report": "The cardiomediastinal silhouette is within normal limits for appearance. No focal areas of pulmonary consolidation. No pneumothorax. No pleural effusion. The thoracic spine appears intact.",
"image_path": [
"CXR1515_IM-0333/0.png",
"CXR1515_IM-0333/1.png"
],
"split": "test"
},
{
"id": "CXR3123_IM-1468",
"report": "The heart is enlarged. Changes of XXXX sternotomy and bypass graft are identified in the lungs are grossly clear. XXXX right pleural thickening versus XXXX pleural effusion is noted. There is no acute infiltrate. No pneumothorax is seen. Mild granulomatous sequela are noted.",
"image_path": [
"CXR3123_IM-1468/0.png",
"CXR3123_IM-1468/1.png"
],
"split": "test"
},
{
"id": "CXR679_IM-2251",
"report": "XXXX sternotomy XXXX are intact and unchanged position from prior exam. Lungs are clear bilaterally with no focal infiltrate, pleural effusion, or pneumothoraces. Cardiomediastinal silhouette is within normal limits. XXXX and soft tissues are unremarkable.",
"image_path": [
"CXR679_IM-2251/0.png",
"CXR679_IM-2251/1.png"
],
"split": "test"
},
{
"id": "CXR1851_IM-0553",
"report": "Heart size is normal. No focal airspace consolidations. No pneumothorax or effusion. No acute osseous findings.",
"image_path": [
"CXR1851_IM-0553/0.png",
"CXR1851_IM-0553/1.png"
],
"split": "test"
},
{
"id": "CXR3204_IM-1513",
"report": "The lungs are clear. There is no pleural effusion. The heart is normal. There are atherosclerotic changes of the aorta. Senescent changes of the spine are seen.",
"image_path": [
"CXR3204_IM-1513/0.png",
"CXR3204_IM-1513/1.png"
],
"split": "test"
},
{
"id": "CXR264_IM-1125",
"report": "Heart XXXX, mediastinum, XXXX, bony structures and lung XXXX are unremarkable. No significant interval change compared to prior study, no XXXX infiltrates noted.",
"image_path": [
"CXR264_IM-1125/0.png",
"CXR264_IM-1125/1.png"
],
"split": "test"
},
{
"id": "CXR2491_IM-1017",
"report": "The cardiomediastinal silhouette and pulmonary vasculature are within normal limits. There is no pneumothorax or pleural effusion. There are no focal areas of consolidation.",
"image_path": [
"CXR2491_IM-1017/0.png",
"CXR2491_IM-1017/1.png"
],
"split": "test"
},
{
"id": "CXR94_IM-2436",
"report": "Heart size, mediastinal contour, and pulmonary vascularity are similar to comparison exam and within normal limits. No focal consolidation, suspicious pulmonary opacity, pleural effusion, or pneumothorax. The visualized osseous structures appear intact.",
"image_path": [
"CXR94_IM-2436/0.png",
"CXR94_IM-2436/1.png"
],
"split": "test"
},
{
"id": "CXR2148_IM-0767",
"report": "Cardiac and mediastinal contours are within normal limits. The lungs are clear. Bony structures are intact.",
"image_path": [
"CXR2148_IM-0767/0.png",
"CXR2148_IM-0767/1.png"
],
"split": "test"
},
{
"id": "CXR278_IM-1218",
"report": "No pneumothorax, pleural effusion, or focal airspace disease. Heart size normal. Stable cardiomediastinal silhouette. Nodular opacities consistent with chronic granulomatous disease. Bony structures intact.",
"image_path": [
"CXR278_IM-1218/0.png",
"CXR278_IM-1218/1.png"
],
"split": "test"
},
{
"id": "CXR1485_IM-0313",
"report": "Again seen are platelike horizontal opacities in both lung bases through this is consistent with scarring or subsegmental atelectasis. There are T-spine osteophytes. The cardiomediastinal silhouette and pulmonary vasculature are within normal limits. There is no pneumothorax or pleural effusion. There there is no lobar pneumonia. There are calcified right hilar granuloma. There are degenerative changes of the XXXX. There is a curvilinear density within and along the right costophrenic sulcus which most XXXX represents a skinfold. There is a unchanged fracture with callus at the left 9th lateral rib.",
"image_path": [
"CXR1485_IM-0313/0.png",
"CXR1485_IM-0313/1.png"
],
"split": "test"
},
{
"id": "CXR164_IM-0419",
"report": "The Cardiopulmonary silhouette is normal. The Heart size is normal. The lungs are clear with no pulmonary effusions or pneumothorax.",
"image_path": [
"CXR164_IM-0419/0.png",
"CXR164_IM-0419/1.png"
],
"split": "test"
},
{
"id": "CXR2773_IM-1214",
"report": "The heart is normal in size and contour. The lungs are clear, without evidence of infiltrate. There is no pneumothorax or effusion. Mild degenerative changes at the lower thoracic spine.",
"image_path": [
"CXR2773_IM-1214/0.png",
"CXR2773_IM-1214/1.png"
],
"split": "test"
},
{
"id": "CXR460_IM-2090",
"report": "The lungs and pleural spaces show no acute abnormality. Heart size and pulmonary vascularity within normal limits. Mild tortuosity of the thoracic aorta, unchanged",
"image_path": [
"CXR460_IM-2090/0.png",
"CXR460_IM-2090/1.png"
],
"split": "test"
},
{
"id": "CXR3898_IM-1978",
"report": "The cardiomediastinal silhouette is normal in size and contour. No focal consolidation, pneumothorax or large pleural effusion. Normal XXXX.",
"image_path": [
"CXR3898_IM-1978/0.png",
"CXR3898_IM-1978/1.png"
],
"split": "test"
},
{
"id": "CXR1409_IM-0260",
"report": "No focal consolidation. No visualized pneumothorax. Heart size and cardiomediastinal silhouette are grossly unremarkable. No large pleural effusions.",
"image_path": [
"CXR1409_IM-0260/0.png",
"CXR1409_IM-0260/1.png"
],
"split": "test"
},
{
"id": "CXR2078_IM-0710",
"report": "The lungs and pleural spaces show no acute abnormality. Heart size and pulmonary vascularity within normal limits.",
"image_path": [
"CXR2078_IM-0710/0.png",
"CXR2078_IM-0710/1.png"
],
"split": "test"
},
{
"id": "CXR1236_IM-0158",
"report": "The cardiomediastinal silhouette and pulmonary vasculature are within normal limits in size. The lungs are clear of focal airspace disease, pneumothorax, or pleural effusion. There are no acute bony findings.",
"image_path": [
"CXR1236_IM-0158/0.png",
"CXR1236_IM-0158/1.png"
],
"split": "test"
},
{
"id": "CXR3798_IM-1911",
"report": "The heart is normal in size. The pulmonary vascularity is within normal limits in appearance. No pneumothorax or pleural effusion. Patchy right lower lung opacification is noted.",
"image_path": [
"CXR3798_IM-1911/0.png",
"CXR3798_IM-1911/1.png"
],
"split": "test"
},
{
"id": "CXR3997_IM-2048",
"report": "Heart size within normal limits. Small, nodular opacity in the right upper lobe. This does not look like an acute infiltrate, and more XXXX represents a granuloma. No pneumothorax or effusions.",
"image_path": [
"CXR3997_IM-2048/0.png",
"CXR3997_IM-2048/1.png"
],
"split": "test"
},
{
"id": "CXR2478_IM-1007",
"report": "There your regular interstitial changes and possibly fibrosis in the left mid and lower lung zone and region of the right middle lobe. Hyperinflation is present. No focal consolidation is seen. There is no evidence for pleural effusion. The heart is not enlarged. Mediastinum is normal. There are arthritic changes of the spine.",
"image_path": [
"CXR2478_IM-1007/0.png",
"CXR2478_IM-1007/1.png"
],
"split": "test"
},
{
"id": "CXR1413_IM-0263",
"report": "Heart size is within normal limits for AP technique. Low lung volumes with bronchovascular crowding. No focal infiltrate. No visible pneumothorax. No pleural effusion.",
"image_path": [
"CXR1413_IM-0263/0.png",
"CXR1413_IM-0263/1.png"
],
"split": "test"
},
{
"id": "CXR3379_IM-1627",
"report": "No pneumothorax or large pleural effusion. Borderline cardiomegaly. Minimal retrocardiac airspace disease. Bony structures appear intact.",
"image_path": [
"CXR3379_IM-1627/0.png",
"CXR3379_IM-1627/1.png"
],
"split": "test"
},
{
"id": "CXR3442_IM-1667",
"report": "Normal cardiomediastinal contours. Low lung volumes with minimal left basilar opacities. No pneumothorax or pleural effusions.",
"image_path": [
"CXR3442_IM-1667/0.png",
"CXR3442_IM-1667/1.png"
],
"split": "test"
},
{
"id": "CXR1034_IM-0028",
"report": "The heart and lungs have XXXX XXXX in the interval. Both lungs are clear and expanded. Right middle lobe calcified granuloma is unchanged. Heart and mediastinum unchanged. No change hiatus hernia.",
"image_path": [
"CXR1034_IM-0028/0.png",
"CXR1034_IM-0028/1.png"
],
"split": "test"
},
{
"id": "CXR681_IM-2252-0001",
"report": "Heart size and pulmonary vascularity appear within normal limits. Right PICC line is in XXXX. The tip has moved into the left innominate vein. There has been interval development of several ill-defined focal opacities in the left and right mid lung zones. No pneumothorax or pleural effusion is seen.",
"image_path": [
"CXR681_IM-2252-0001/0.png",
"CXR681_IM-2252-0001/1.png"
],
"split": "test"
},
{
"id": "CXR721_IM-2282",
"report": "Lungs are clear. No pleural effusions or pneumothoraces. Heart and mediastinum of normal size and contour.",
"image_path": [
"CXR721_IM-2282/0.png",
"CXR721_IM-2282/1.png"
],
"split": "test"
},
{
"id": "CXR1914_IM-0595",
"report": "Stable heart size. Diffuse bilateral interstitial opacities. No pneumothorax. No effusions. No acute bony abnormalities.",
"image_path": [
"CXR1914_IM-0595/0.png",
"CXR1914_IM-0595/1.png"
],
"split": "test"
},
{
"id": "CXR628_IM-2208",
"report": "Frontal and lateral views of the chest with overlying external cardiac monitor leads show an unchanged cardiomediastinal silhouette. Cardiac silhouette at the upper limits of normal in size. Tortuous ectatic aorta. The aortic XXXX is near 5 cm in diameter. There is a retrocardiac left paraspinal bulge concerning for a descending thoracic aortic aneurysm. There is biapical scarring. No XXXX focal airspace consolidation or pleural effusion. XXXX spine spondylitic changes.",
"image_path": [
"CXR628_IM-2208/0.png",
"CXR628_IM-2208/1.png"
],
"split": "test"
},
{
"id": "CXR368_IM-1832",
"report": "Cardiomediastinal silhouette and pulmonary vasculature are within normal limits. Lungs are clear. No pneumothorax or pleural effusion. No acute osseous findings.",
"image_path": [
"CXR368_IM-1832/0.png",
"CXR368_IM-1832/1.png"
],
"split": "test"
},
{
"id": "CXR2843_IM-1254-1001",
"report": "The heart is normal in size. There is right paratracheal density concerning for lymphadenopathy. There are patchy right upper lobe streaky opacities. The remainder of the lungs are clear. There is no pleural effusion.",
"image_path": [
"CXR2843_IM-1254-1001/0.png",
"CXR2843_IM-1254-1001/1.png"
],
"split": "test"
},
{
"id": "CXR383_IM-1932",
"report": "Normal heart size. No focal air space consolidation, pneumothorax, pleural effusion, or pulmonary edema. Anterior osteophytes of the thoracic spine.",
"image_path": [
"CXR383_IM-1932/0.png",
"CXR383_IM-1932/1.png"
],
"split": "test"
},
{
"id": "CXR1393_IM-0251",
"report": "Right central venous line has been removed. Heart size and pulmonary vascularity appear within normal limits. A few bandlike opacities are present at the lateral left base. The appearance XXXX scarring or atelectasis. No focal airspace disease is seen. No discrete nodules are identified. No pneumothorax or pleural effusion is seen.",
"image_path": [
"CXR1393_IM-0251/0.png",
"CXR1393_IM-0251/1.png"
],
"split": "test"
},
{
"id": "CXR3816_IM-1925",
"report": "Heart size is at the upper limits of normal. The pulmonary vascularity appears within normal limits. The lungs are free of focal airspace disease. No pleural effusion or pneumothorax is seen. Degenerative changes are present in the spine. No non-calcified nodules are identified.",
"image_path": [
"CXR3816_IM-1925/0.png",
"CXR3816_IM-1925/1.png"
],
"split": "test"
},
{
"id": "CXR3522_IM-1720",
"report": "Lungs are clear. There is no pneumothorax or pleural effusion. The heart and mediastinum are within normal limits. Bony structures are intact.",
"image_path": [
"CXR3522_IM-1720/0.png",
"CXR3522_IM-1720/1.png"
],
"split": "test"
},
{
"id": "CXR1739_IM-0487",
"report": "There is a cortical irregularity along the anterior margin of the sternum. In addition, there is a focal retrosternal hypodense convexity. The cardiac silhouette is within normal limits. The thoracic aorta is torturous however the mediastinal contours are within normal limits. There is no pneumothorax. There is no large pleural effusion. There is streaky XXXX opacity within the left lung base XXXX representing atelectasis. Otherwise, the lungs are clear. There is thoracic kyphosis. There is hyperinflation of the lungs.",
"image_path": [
"CXR1739_IM-0487/0.png",
"CXR1739_IM-0487/1.png"
],
"split": "test"
},
{
"id": "CXR659_IM-2235",
"report": "Heart size within normal limits. Tortuous aorta. Low lung volumes with no focal consolidations. No pneumothorax or effusion. Moderate degenerative disc disease in the midthoracic spine.",
"image_path": [
"CXR659_IM-2235/0.png",
"CXR659_IM-2235/1.png"
],
"split": "test"
},
{
"id": "CXR3578_IM-1758",
"report": "The heart and lungs have XXXX XXXX in the interval. Both lungs are clear and expanded. Heart and mediastinum normal.",
"image_path": [
"CXR3578_IM-1758/0.png",
"CXR3578_IM-1758/1.png"
],
"split": "test"
},
{
"id": "CXR2130_IM-0755",
"report": "Cardiomegaly is present. There is interstitial pulmonary edema with the presence of XXXX B-lines. There is no pneumothorax. There is an oval, 17 mm nodular opacity projecting between the posterior left 5th and 6th ribs. There is a 10 mm nodular density projecting over the right posterior 4th rib. There is a XXXX posterior effusion. Normal mediastinal silhouette. T-spine osteophytes.",
"image_path": [
"CXR2130_IM-0755/0.png",
"CXR2130_IM-0755/1.png"
],
"split": "test"
},
{
"id": "CXR3609_IM-1782",
"report": "There is borderline cardiomegaly. Mediastinum and pulmonary vasculature are unremarkable. Lungs are clear. No pleural fluid or pneumothorax is appreciated.",
"image_path": [
"CXR3609_IM-1782/0.png",
"CXR3609_IM-1782/1.png"
],
"split": "test"
},
{
"id": "CXR1523_IM-0339",
"report": "Heart size, cardiomediastinal silhouette, and pulmonary vasculature are within normal limits. There are no infiltrates, effusions, or pneumothorax.",
"image_path": [
"CXR1523_IM-0339/0.png",
"CXR1523_IM-0339/1.png"
],
"split": "test"
},
{
"id": "CXR2138_IM-0760",
"report": "Normal heart size. Stable tortuous thoracic aorta. Prior granulomatous disease. Healed rib fractures appear stable. Focal opacity is noted in the left midlung overlying the 9th posterior rib which XXXX represents healing rib callus. No pneumothorax or pleural effusion.",
"image_path": [
"CXR2138_IM-0760/0.png",
"CXR2138_IM-0760/1.png"
],
"split": "test"
},
{
"id": "CXR261_IM-1100",
"report": "No focal areas of consolidation. Heart size within normal limits. No pleural effusions. No evidence of pneumothorax. Osseous structures appear intact.",
"image_path": [
"CXR261_IM-1100/0.png",
"CXR261_IM-1100/1.png"
],
"split": "test"
},
{
"id": "CXR1640_IM-0420",
"report": "The heart is normal in size. The mediastinum is unremarkable. Small nodule in the right upper lung is stable. The lungs are otherwise clear.",
"image_path": [
"CXR1640_IM-0420/0.png",
"CXR1640_IM-0420/1.png"
],
"split": "test"
},
{
"id": "CXR1919_IM-0598",
"report": "Hyperexpansion of the lungs with hyperlucency and flattening of hemidiaphragms suggestive of chronic emphysematous lung disease. Heart size within normal limits. Bibasilar, right greater than left atelectasis/airspace disease noted. No pneumothorax or large pleural effusion. No acute bony abnormality.",
"image_path": [
"CXR1919_IM-0598/0.png",
"CXR1919_IM-0598/1.png"
],
"split": "test"
},
{
"id": "CXR421_IM-2064",
"report": "Lungs are clear without focal consolidation, effusion, or pneumothorax. Normal heart size. Bony thorax and soft tissues grossly unremarkable. Negative for pneumoperitoneum.",
"image_path": [
"CXR421_IM-2064/0.png",
"CXR421_IM-2064/1.png"
],
"split": "test"
},
{
"id": "CXR1853_IM-0555",
"report": "The lungs are clear bilaterally. Specifically, no evidence of focal consolidation, pneumothorax, or pleural effusion. Cardiomediastinal silhouette is unremarkable. Visualized osseous structures of the thorax are without acute abnormality.",
"image_path": [
"CXR1853_IM-0555/0.png",
"CXR1853_IM-0555/1.png"
],
"split": "test"
},
{
"id": "CXR97_IM-2460",
"report": "The cardiac contours are normal. The lungs are clear. Thoracic spondylosis.",
"image_path": [
"CXR97_IM-2460/0.png",
"CXR97_IM-2460/1.png"
],
"split": "test"
},
{
"id": "CXR2787_IM-1222",
"report": "No pneumothorax, pleural effusion or airspace consolidation. Heart size is upper limits of normal. Pulmonary vasculature appear within normal limits. XXXX XXXX are intact.",
"image_path": [
"CXR2787_IM-1222/0.png",
"CXR2787_IM-1222/1.png"
],
"split": "test"
},
{
"id": "CXR2608_IM-1098",
"report": "Consolidation and costophrenic XXXX blunting persists in both lower lobes. Heart and pulmonary XXXX remain normal. No XXXX infiltrates.",
"image_path": [
"CXR2608_IM-1098/0.png",
"CXR2608_IM-1098/1.png"
],
"split": "test"
},
{
"id": "CXR2108_IM-0738",
"report": "The heart and lungs have XXXX XXXX in the interval. Both lungs are clear and expanded. Heart and mediastinum normal.",
"image_path": [
"CXR2108_IM-0738/0.png",
"CXR2108_IM-0738/1.png"
],
"split": "test"
},
{
"id": "CXR3846_IM-1946",
"report": "Heart size and mediastinal contour are normal. Pulmonary vascularity is normal. The right lung is clear. There is a recurrence moderate-sized left pleural effusion. No pneumothorax. Limited right base stringy density compatible with atelectasis. Dextroscoliosis of the thoracic spine.",
"image_path": [
"CXR3846_IM-1946/0.png",
"CXR3846_IM-1946/1.png"
],
"split": "test"
},
{
"id": "CXR450_IM-2082",
"report": "No focal consolidation. No pneumothorax. No pleural effusions. Heart size normal. Cardio mediastinal silhouette is unremarkable.",
"image_path": [
"CXR450_IM-2082/0.png",
"CXR450_IM-2082/1.png"
],
"split": "test"
},
{
"id": "CXR3173_IM-1495",
"report": "Lungs are clear. Heart size normal. No pneumothorax.",
"image_path": [
"CXR3173_IM-1495/0.png",
"CXR3173_IM-1495/1.png"
],
"split": "test"
},
{
"id": "CXR1681_IM-0448",
"report": "Both lungs are clear and expanded. Heart and mediastinum normal.",
"image_path": [
"CXR1681_IM-0448/0.png",
"CXR1681_IM-0448/1.png"
],
"split": "test"
},
{
"id": "CXR352_IM-1718",
"report": "The cardiomediastinal silhouette is within normal limits for appearance. The trachea is midline. No focal pulmonary consolidation. No pneumothorax. No pleural effusion. Minimal degenerative changes of the thoracic spine.",
"image_path": [
"CXR352_IM-1718/0.png",
"CXR352_IM-1718/1.png"
],
"split": "test"
},
{
"id": "CXR3519_IM-1717",
"report": "Large left lower lobe opacity is present. There does not appear to be significant mediastinal shift. There is no pneumothorax. The cardiac silhouette is not definitively identified and not fully evaluated. The mediastinal contours are unremarkable.",
"image_path": [
"CXR3519_IM-1717/0.png",
"CXR3519_IM-1717/1.png"
],
"split": "test"
},
{
"id": "CXR3589_IM-1767",
"report": "Cardiomediastinal contour and pulmonary vascularity stable and within normal limits. Lung volumes are slightly low. There are streaky left basal opacities. No pleural effusion or pneumothorax. No acute osseous findings. No free air is demonstrated.",
"image_path": [
"CXR3589_IM-1767/0.png",
"CXR3589_IM-1767/1.png"
],
"split": "test"
},
{
"id": "CXR1685_IM-0449",
"report": "Hyperinflated lungs with mildly flattened posterior diaphragm. No focal alveolar consolidation, no definite pleural effusion seen. Heart size within normal limits, no typical findings of pulmonary edema.",
"image_path": [
"CXR1685_IM-0449/0.png",
"CXR1685_IM-0449/1.png"
],
"split": "test"
},
{
"id": "CXR3180_IM-1500",
"report": "The heart is normal in size and contour. The lungs are clear, without evidence of infiltrate. There is no pneumothorax or effusion.",
"image_path": [
"CXR3180_IM-1500/0.png",
"CXR3180_IM-1500/1.png"
],
"split": "test"
},
{
"id": "CXR2733_IM-1189",
"report": "Bibasilar airspace opacities, right greater than left. The heart size and mediastinal silhouette are within normal limits for contour. No pneumothorax or pleural effusions. The XXXX are intact.",
"image_path": [
"CXR2733_IM-1189/0.png",
"CXR2733_IM-1189/1.png"
],
"split": "test"
},
{
"id": "CXR699_IM-2263",
"report": "Stable enlargement of the cardiac silhouette, stable mediastinal contours. Increased interstitial markings in the central lungs and bases, right greater than left. XXXX opacity on the lateral view over the heart also present on the previous exam suggesting chronic subsegmental atelectasis or scarring. No definite pleural effusion seen.",
"image_path": [
"CXR699_IM-2263/0.png",
"CXR699_IM-2263/1.png"
],
"split": "test"
},
{
"id": "CXR3849_IM-1947",
"report": "Cardiomediastinal silhouettes are within normal limits. Lungs are clear without focal consolidation, pneumothorax, or pleural effusion. Degenerative disease is seen in the thoracic spine and left XXXX XXXX.",
"image_path": [
"CXR3849_IM-1947/0.png",
"CXR3849_IM-1947/1.png"
],
"split": "test"
},
{
"id": "CXR2616_IM-1106",
"report": "Frontal and lateral views of the chest show normal size and configuration of the cardiac silhouette. The right costophrenic sulcus is blunted. There is an the right base XXXX/fluid level. The left lung is clear.",
"image_path": [
"CXR2616_IM-1106/0.png",
"CXR2616_IM-1106/1.png"
],
"split": "test"
},
{
"id": "CXR745_IM-2299",
"report": "The lungs are clear. There is no pleural effusion or pneumothorax. The heart is not significantly enlarged. There are atherosclerotic changes of the aorta. Arthritic changes of the skeletal structures are noted.",
"image_path": [
"CXR745_IM-2299/0.png",
"CXR745_IM-2299/1.png"
],
"split": "test"
},
{
"id": "CXR1011_IM-0013",
"report": "The heart is top normal in size. The mediastinum is unremarkable. The lungs are clear.",
"image_path": [
"CXR1011_IM-0013/0.png",
"CXR1011_IM-0013/1.png"
],
"split": "test"
},
{
"id": "CXR2052_IM-0690",
"report": "Lungs are clear without focal consolidation, effusion, or pneumothorax. Normal heart size. Scattered granulomatous changes. Mild unfolding of the thoracic aorta. Bony thorax is unremarkable",
"image_path": [
"CXR2052_IM-0690/0.png",
"CXR2052_IM-0690/1.png"
],
"split": "test"
},
{
"id": "CXR2529_IM-1044",
"report": "The lungs are clear bilaterally. Specifically, no evidence of focal consolidation, pneumothorax, or pleural effusion.. Cardio mediastinal silhouette is unremarkable. Visualized osseous structures of the thorax are without acute abnormality.",
"image_path": [
"CXR2529_IM-1044/0.png",
"CXR2529_IM-1044/1.png"
],
"split": "test"
},
{
"id": "CXR2074_IM-0708",
"report": "Low lung volumes. Stable ectasia of the thoracic aorta. Stable right upper mediastinal Bilateral small pleural effusions and bibasilar airspace opacities. The heart size and mediastinal silhouette are within normal limits for contour. No pneumothorax. Stable wedging of the anterior thoracic vertebral bodies.",
"image_path": [
"CXR2074_IM-0708/0.png",
"CXR2074_IM-0708/1.png"
],
"split": "test"
},
{
"id": "CXR3294_IM-1573",
"report": "The cardiomediastinal silhouette is within normal limits for appearance. The thoracic aorta is tortuous. A calcified granuloma is identified in the right middle lobe. No focal areas of pulmonary consolidation. No pneumothorax. No pleural effusion. The thoracic spine appears intact. No acute displaced rib fractures.",
"image_path": [
"CXR3294_IM-1573/0.png",
"CXR3294_IM-1573/1.png"
],
"split": "test"
},
{
"id": "CXR543_IM-2148",
"report": "The lungs are clear. The cardiomediastinal silhouette is within normal limits. No pleural effusion is identified.",
"image_path": [
"CXR543_IM-2148/0.png",
"CXR543_IM-2148/1.png"
],
"split": "test"
},
{
"id": "CXR3000_IM-1386-0001",
"report": "There are multiple bilateral pulmonary nodules. For example, there is a 12 mm left lower lobe nodule, XXXX seen on the frontal view. There is no pleural effusion or pneumothorax. Heart size is within normal limits. The left hilar contour is prominent. There are diffuse degenerative changes of the spine.",
"image_path": [
"CXR3000_IM-1386-0001/0.png",
"CXR3000_IM-1386-0001/1.png"
],
"split": "test"
},
{
"id": "CXR2259_IM-0850",
"report": "Bilateral glenohumeral degenerative joint disease. Scattered degenerative changes of the thoracic spine. Stable mild heart enlargement.Prominence of soft tissue density in the upper mediastinum. It is increased from most recent prior exam on XXXX. However, it appears similar compared to XXXX exams performed in XXXX. No focal area of consolidation, pleural effusion, or pneumothorax. Focal opacity in the left upper lobe XXXX represents scarring or related to overlying rib opacity.",
"image_path": [
"CXR2259_IM-0850/0.png",
"CXR2259_IM-0850/1.png"
],
"split": "test"
},
{
"id": "CXR1180_IM-0123",
"report": "Heart size and pulmonary vascularity appear within normal limits. There is mild tortuosity to the descending thoracic aorta. The lungs are free of focal airspace disease. No pleural effusion or pneumothorax is seen. No discrete nodules or adenopathy are noted. Degenerative changes are present in the spine.",
"image_path": [
"CXR1180_IM-0123/0.png",
"CXR1180_IM-0123/1.png"
],
"split": "test"
},
{
"id": "CXR106_IM-0042",
"report": "Heart size and mediastinal contour are normal. Pulmonary vascularity is normal. Lungs are clear. No pleural effusions or pneumothoraces.",
"image_path": [
"CXR106_IM-0042/0.png",
"CXR106_IM-0042/1.png"
],
"split": "test"
},
{
"id": "CXR2243_IM-0840",
"report": "The heart is normal size. The mediastinum is unremarkable. There is no pleural effusion, pneumothorax, or focal airspace disease. There is a stable calcified granuloma within the left lower lobe. There are stable chronic degenerative changes of the thoracic spine.",
"image_path": [
"CXR2243_IM-0840/0.png",
"CXR2243_IM-0840/1.png"
],
"split": "test"
},
{
"id": "CXR76_IM-2309",
"report": "Apparent scarring within the lingula. Lungs are otherwise clear. No pleural effusions or pneumothoraces. Heart and mediastinum of normal size and contour.",
"image_path": [
"CXR76_IM-2309/0.png",
"CXR76_IM-2309/1.png"
],
"split": "test"
},
{
"id": "CXR3570_IM-1754",
"report": "Normal heart size mediastinal contours. Subsegmental atelectasis versus scarring in the right midlung and left lower lobe. No focal airspace disease. No pleural effusion or pneumothorax. Low lung volumes. Visualized bony structures are unremarkable in appearance.",
"image_path": [
"CXR3570_IM-1754/0.png",
"CXR3570_IM-1754/1.png"
],
"split": "test"
},
{
"id": "CXR3139_IM-1476",
"report": "No focal areas of consolidation. No pleural effusions. No evidence of pneumothorax. Heart size within normal limits. Osseous structures intact.",
"image_path": [
"CXR3139_IM-1476/0.png",
"CXR3139_IM-1476/1.png"
],
"split": "test"
},
{
"id": "CXR1273_IM-0183",
"report": "Heart is mildly enlarged stable. Mediastinal contour is normal. Pulmonary vascularity is normal. Lungs are hyperexpanded but clear. No pleural effusions or pneumothoraces.",
"image_path": [
"CXR1273_IM-0183/0.png",
"CXR1273_IM-0183/1.png"
],
"split": "test"
},
{
"id": "CXR3449_IM-1672",
"report": "The XXXX examination consists of frontal and lateral radiographs of the chest. External monitor leads XXXX the thorax. The cardiomediastinal contours are within normal limits. Pulmonary vascularity is within normal limits. No focal consolidation, pleural effusion, or pneumothorax identified. The visualized osseous structures and upper abdomen are unremarkable.",
"image_path": [
"CXR3449_IM-1672/0.png",
"CXR3449_IM-1672/1.png"
],
"split": "test"
},
{
"id": "CXR3384_IM-1631",
"report": "Both lungs are clear and expanded. Heart and mediastinum normal.",
"image_path": [
"CXR3384_IM-1631/0.png",
"CXR3384_IM-1631/1.png"
],
"split": "test"
},
{
"id": "CXR622_IM-2204",
"report": "Both lungs are clear and expanded. Heart and mediastinum normal.",
"image_path": [
"CXR622_IM-2204/0.png",
"CXR622_IM-2204/1.png"
],
"split": "test"
},
{
"id": "CXR1873_IM-0565",
"report": "Cardiomediastinal silhouette is within normal limits. No focal consolidation, pneumothorax, or pleural effusion. No acute bony abnormalities. Degenerative changes of the thoracic spine.",
"image_path": [
"CXR1873_IM-0565/0.png",
"CXR1873_IM-0565/1.png"
],
"split": "test"
},
{
"id": "CXR3411_IM-1649-0001",
"report": "There are low lung volumes with bronchovascular crowding. There is patchy left lower lobe airspace disease. There are XXXX opacities in the right mid lung, XXXX subsegmental atelectasis. No significant pleural effusion. No pneumothorax. Heart size is within normal limits. There is aortic atherosclerotic vascular calcification.",
"image_path": [
"CXR3411_IM-1649-0001/0.png",
"CXR3411_IM-1649-0001/1.png"
],
"split": "test"
},
{
"id": "CXR1472_IM-0305",
"report": "Normal cardiac contour. Clear hyperexpanded lungs bilaterally with no pneumothorax or pleural effusion.",
"image_path": [
"CXR1472_IM-0305/0.png",
"CXR1472_IM-0305/1.png"
],
"split": "test"
},
{
"id": "CXR260_IM-1090",
"report": "Lungs are clear bilaterally. Cardiac and mediastinal silhouettes are normal. Pulmonary vasculature is normal. No pneumothorax or pleural effusion. No acute bony abnormality. There is a stable the electronic device any left anterior chest wall. There are advanced degenerative changes in the XXXX bilaterally. There is a 38 mm lucency in the right humeral head with geographic 1A margins.",
"image_path": [
"CXR260_IM-1090/0.png",
"CXR260_IM-1090/1.png"
],
"split": "test"
},
{
"id": "CXR1526_IM-0341",
"report": "No focal consolidation. No visualized pneumothorax. No large pleural effusions. The heart size and cardiomediastinal silhouette is grossly unremarkable. There is motion artifact on the lateral radiograph.",
"image_path": [
"CXR1526_IM-0341/0.png",
"CXR1526_IM-0341/1.png"
],
"split": "test"
},
{
"id": "CXR145_IM-0290",
"report": "Right costophrenic XXXX is blunted. In the left lower lobe a patchy infiltrate is present. The pulmonary XXXX are normal.",
"image_path": [
"CXR145_IM-0290/0.png",
"CXR145_IM-0290/1.png"
],
"split": "test"
},
{
"id": "CXR93_IM-2428",
"report": "Lungs are clear without focal consolidation, effusion, or pneumothorax. Normal heart size. Negative for pneumoperitoneum. Mild degenerative changes of the thoracic spine.",
"image_path": [
"CXR93_IM-2428/0.png",
"CXR93_IM-2428/1.png"
],
"split": "test"
},
{
"id": "CXR429_IM-2070",
"report": "The cardiomediastinal silhouette and pulmonary vasculature are within normal limits in size. The lungs are clear of focal airspace disease, pneumothorax, or pleural effusion. There is no definite evidence of acute fracture.",
"image_path": [
"CXR429_IM-2070/0.png",
"CXR429_IM-2070/1.png"
],
"split": "test"
},
{
"id": "CXR13_IM-0198",
"report": "The cardiac silhouette is borderline enlarged. Otherwise, there is no focal opacity. Mediastinal contours are within normal limits. There is no large pleural effusion. No pneumothorax.",
"image_path": [
"CXR13_IM-0198/0.png",
"CXR13_IM-0198/1.png"
],
"split": "test"
},
{
"id": "CXR1113_IM-0078",
"report": "Previous sulcal is normal in size and contour. Lungs are clear. No focal consolidation, pneumothorax, or pleural effusion. Interval resolution of previously described right midlung opacity suggesting resolved inflammatory/infectious process. Lungs are hyperexpanded with flattened diaphragms. XXXX and soft tissue are unremarkable.",
"image_path": [
"CXR1113_IM-0078/0.png",
"CXR1113_IM-0078/1.png"
],
"split": "test"
},
{
"id": "CXR3423_IM-1656",
"report": "the heart size is normal. There is tortuosity of aorta. Pulmonary vascularity is normal. No focal airspace disease or effusion. Degenerative changes in the thoracic spine.",
"image_path": [
"CXR3423_IM-1656/0.png",
"CXR3423_IM-1656/1.png"
],
"split": "test"
},
{
"id": "CXR3878_IM-1968",
"report": "Postop changes of CABG with mild cardiomegaly. There is an infiltrate in the right lower lobe. Thoracic spondylosis.",
"image_path": [
"CXR3878_IM-1968/0.png",
"CXR3878_IM-1968/1.png"
],
"split": "test"
},
{
"id": "CXR3422_IM-1656",
"report": "Heart size normal. Lungs are clear. XXXX are normal. No pneumonia, effusions, edema, pneumothorax, adenopathy, nodules or masses.",
"image_path": [
"CXR3422_IM-1656/0.png",
"CXR3422_IM-1656/1.png"
],
"split": "test"
},
{
"id": "CXR1429_IM-0275",
"report": "Mediastinal contours are normal. Heart size is within normal limits. Lungs are clear. There is no pneumothorax or large pleural effusion.",
"image_path": [
"CXR1429_IM-0275/0.png",
"CXR1429_IM-0275/1.png"
],
"split": "test"
},
{
"id": "CXR107_IM-0049",
"report": "The lungs are clear bilaterally. Specifically, no evidence of focal consolidation, pneumothorax, or pleural effusion.. Cardio mediastinal silhouette is unremarkable. Visualized osseous structures of the thorax are without acute abnormality.",
"image_path": [
"CXR107_IM-0049/0.png",
"CXR107_IM-0049/1.png"
],
"split": "test"
},
{
"id": "CXR753_IM-2306",
"report": "The heart, pulmonary XXXX and mediastinum are within normal limits. There is no pleural effusion or pneumothorax. There is no focal air space opacity to suggest a pneumonia. There are mild degenerative changes of the spine.",
"image_path": [
"CXR753_IM-2306/0.png",
"CXR753_IM-2306/1.png"
],
"split": "test"
},
{
"id": "CXR2924_IM-1327",
"report": "The heart size is normal. The mediastinal contour is within normal limits. The lungs are free of any focal infiltrates. There is a small calcified granuloma within the left upper lobe. There are no nodules or masses. No visible pneumothorax. No visible pleural fluid. The XXXX are grossly normal. There is no visible free intraperitoneal air under the diaphragm.",
"image_path": [
"CXR2924_IM-1327/0.png",
"CXR2924_IM-1327/1.png"
],
"split": "test"
},
{
"id": "CXR950_IM-2446",
"report": "The cardiomediastinal silhouette and pulmonary vasculature are within normal limits. There is no pneumothorax or pleural effusion. There are no focal areas of consolidation.",
"image_path": [
"CXR950_IM-2446/0.png",
"CXR950_IM-2446/1.png"
],
"split": "test"
},
{
"id": "CXR3430_IM-1659",
"report": "Heart size mildly to moderately enlarged, distal tip dual-lumen catheter near the caval atrial junction. Mild vascular cephalization, no definite interstitial changes of pulmonary edema, no focal alveolar consolidation. No pleural effusion XXXX demonstrated.",
"image_path": [
"CXR3430_IM-1659/0.png",
"CXR3430_IM-1659/1.png"
],
"split": "test"
},
{
"id": "CXR3772_IM-1891",
"report": "The heart size and pulmonary vascularity appear within normal limits. The lungs are free of focal airspace disease. No pleural effusion or pneumothorax is seen. Calcified granuloma are present. Degenerative changes are present in the spine.",
"image_path": [
"CXR3772_IM-1891/0.png",
"CXR3772_IM-1891/1.png"
],
"split": "test"
},
{
"id": "CXR290_IM-1303",
"report": "The lungs are clear. There are multiple surgical XXXX seen near the apical regions and lower cervical region bilaterally. The heart and mediastinum are normal. There is a screw in the right shoulder. The soft tissues are normal.",
"image_path": [
"CXR290_IM-1303/0.png",
"CXR290_IM-1303/1.png"
],
"split": "test"
},
{
"id": "CXR458_IM-2089",
"report": "The lungs are clear. The heart and pulmonary XXXX are normal. The pleural spaces are clear. Mediastinal contours are normal. Bony overlap in the lung apices could obscure a small pulmonary nodule.",
"image_path": [
"CXR458_IM-2089/0.png",
"CXR458_IM-2089/1.png"
],
"split": "test"
},
{
"id": "CXR2_IM-0652",
"report": "Borderline cardiomegaly. Midline sternotomy XXXX. Enlarged pulmonary arteries. Clear lungs. Inferior XXXX XXXX XXXX.",
"image_path": [
"CXR2_IM-0652/0.png",
"CXR2_IM-0652/1.png"
],
"split": "test"
},
{
"id": "CXR64_IM-2218",
"report": "2 images. Heart size upper limits of normal. Mediastinal contours are maintained. The patient is mildly rotated. There is a small to moderate sized right apical pneumothorax which measures approximately 2.0 cm. No focal airspace consolidation is seen. Left chest is clear. No definite displaced bony injury is seen. Results called XXXX. XXXX XXXX p.m. XXXX, XXXX.",
"image_path": [
"CXR64_IM-2218/0.png",
"CXR64_IM-2218/1.png"
],
"split": "test"
},
{
"id": "CXR2612_IM-1103",
"report": "The cardiomediastinal silhouette and pulmonary vasculature are within normal limits in size. The lungs are clear of focal airspace disease, pneumothorax, or pleural effusion. There are no acute bony findings.",
"image_path": [
"CXR2612_IM-1103/0.png",
"CXR2612_IM-1103/1.png"
],
"split": "test"
},
{
"id": "CXR1004_IM-0005",
"report": "The heart, pulmonary XXXX and mediastinum are within normal limits. There is no pleural effusion or pneumothorax. There is no focal air space opacity to suggest a pneumonia. The aorta is tortuous and ectatic. There are degenerative changes of the acromioclavicular joints. There degenerative changes of the spine. There is an IVC XXXX identified.",
"image_path": [
"CXR1004_IM-0005/0.png",
"CXR1004_IM-0005/1.png"
],
"split": "test"
},
{
"id": "CXR226_IM-0851",
"report": "The cardiac contours are normal. The lungs are clear. Thoracic spondylosis.",
"image_path": [
"CXR226_IM-0851/0.png",
"CXR226_IM-0851/1.png"
],
"split": "test"
},
{
"id": "CXR1708_IM-0466",
"report": "The cardiomediastinal silhouette is within normal limits for appearance. No focal areas of pulmonary consolidation. Calcified lymph XXXX are identified in the left infrahilar region. No pneumothorax. No pleural effusion. No acute, displaced rib fractures identified.",
"image_path": [
"CXR1708_IM-0466/0.png",
"CXR1708_IM-0466/1.png"
],
"split": "test"
},
{
"id": "CXR2312_IM-0887",
"report": "The heart is normal in size. The mediastinum is unremarkable. The lungs are clear.",
"image_path": [
"CXR2312_IM-0887/0.png",
"CXR2312_IM-0887/1.png"
],
"split": "test"
},
{
"id": "CXR49_IM-2110",
"report": "The heart, pulmonary XXXX and mediastinum are within normal limits. There is no pleural effusion or pneumothorax. There is no focal air space opacity to suggest a pneumonia. There are degenerative changes of the thoracic spine. There is a calcified granuloma identified in the right suprahilar region. The aorta is mildly tortuous and ectatic. There is asymmetric right apical smooth pleural thickening. There are severe degenerative changes of the XXXX.",
"image_path": [
"CXR49_IM-2110/0.png",
"CXR49_IM-2110/1.png"
],
"split": "test"
}
]
================================================
FILE: data/test/report/mimic_test.json
================================================
[
{
"id": "0c5f56c2-3d707105-b36af285-88d0ae60-48ef3fda",
"study_id": 53078789,
"subject_id": 15518538,
"report": "impression: No acute cardiopulmonary process. Findings: The lungs are clear. The cardiomediastinal silhouette is within normal limits.\n Median sternotomy wires are again noted with fractures of the superior most\n wires. No acute osseous abnormalities identified.",
"image_path": [
"p15/p15518538/s53078789/0c5f56c2-3d707105-b36af285-88d0ae60-48ef3fda.jpg"
],
"split": "test"
},
{
"id": "62e28fc5-93fe9a0b-36f25627-e72bcdc7-fddf5f6e",
"study_id": 56605732,
"subject_id": 18570152,
"report": "impression: Mild cardiomegaly and central pulmonary vascular congestion. Findings: A left pectoral pacemaker is noted with a single intact lead. The heart is\n mildly enlarged. Mild central pulmonary vascular congestion is noted. \n Bibasilar airspace opacities likely reflect atelectasis. There is no lobar\n consolidation, large pleural effusion, or pneumothorax.",
"image_path": [
"p18/p18570152/s56605732/62e28fc5-93fe9a0b-36f25627-e72bcdc7-fddf5f6e.jpg"
],
"split": "test"
},
{
"id": "c89c0bac-453ca322-9aec3b3a-af1073e8-833e0ccd",
"study_id": 59343122,
"subject_id": 18767957,
"report": "impression: Findings suggestive of interstitial edema. No superimposed acute\n consolidation or effusion. Unchanged cardiomegaly. Findings: PA and lateral views of the chest. The lungs are clear of focal consolidation\n or pleural effusion. There are however increased interstitial markings\n throughout the lungs and enlarged cardiac silhouette which is unchanged from\n prior. There is no acute osseous abnormality detected.",
"image_path": [
"p18/p18767957/s59343122/c89c0bac-453ca322-9aec3b3a-af1073e8-833e0ccd.jpg"
],
"split": "test"
},
{
"id": "fe5ade20-832e5f10-2fcedcb6-4c3c8557-e8bfb513",
"study_id": 51246566,
"subject_id": 18828251,
"report": "As compared to the previous radiograph, the pre-existing right\n upper lobe pneumonia is completely resolved. The pre-existing signs of mild\n fluid overload, however, are still present. The pre-existing cardiomegaly is\n unchanged. Several calcified lung nodules are also unchanged. Unchanged\n alignment of the sternal wires. No acute pneumonia, no pleural effusions.",
"image_path": [
"p18/p18828251/s51246566/fe5ade20-832e5f10-2fcedcb6-4c3c8557-e8bfb513.jpg"
],
"split": "test"
},
{
"id": "a67e2e2b-c5902ccf-adf291f3-51b417af-5b71eeaa",
"study_id": 52874049,
"subject_id": 17327592,
"report": "impression: Unchanged chronic elevation of the right hemidiaphragm with right basilar\n atelectasis. No new focal consolidation. Findings: Patient is status post median sternotomy and CABG. Heart size is normal. The\n mediastinal contours are unchanged. Right hemidiaphragm remains elevated with\n associated right basilar atelectasis. Pulmonary vasculature is not engorged.\n Left lung is grossly clear. No pleural effusion or pneumothorax is\n demonstrated. There are no acute osseous abnormalities. Mild to moderate\n multilevel degenerative changes are noted in the thoracic spine.",
"image_path": [
"p17/p17327592/s52874049/a67e2e2b-c5902ccf-adf291f3-51b417af-5b71eeaa.jpg"
],
"split": "test"
},
{
"id": "686a2b90-af0e2b68-75f6acc2-ea6fecdc-a69f5c88",
"study_id": 56836177,
"subject_id": 13475033,
"report": "impression: Stable prominence of the interstitial markings bilaterally. No new focal\n consolidation seen. Findings: Cardiac and mediastinal silhouettes are stable. There is stable diffuse\n prominence of the interstitial markings. No pleural effusion or pneumothorax\n is seen.",
"image_path": [
"p13/p13475033/s56836177/686a2b90-af0e2b68-75f6acc2-ea6fecdc-a69f5c88.jpg"
],
"split": "test"
},
{
"id": "e9683fa3-283e5f0c-c05c217c-b320d070-4a8e9fc0",
"study_id": 55484286,
"subject_id": 17318449,
"report": "impression: Left lower lobe consolidation, may represent pneumonia or\n aspiration. Findings: There is a new consolidation in the retrocardiac left lung\n base, concerning for pneumonia or aspiration. No pleural effusion or\n pneumothorax is seen. There is mild pulmonary vascular congestion. The\n mediastinal silhouette is unchanged. Multiple intact mediastinal wires relate\n to prior sternotomy.",
"image_path": [
"p17/p17318449/s55484286/e9683fa3-283e5f0c-c05c217c-b320d070-4a8e9fc0.jpg"
],
"split": "test"
},
{
"id": "63f854b9-c24c2a15-3c4ee54e-72c08c57-5b8bcf18",
"study_id": 50482541,
"subject_id": 16957952,
"report": "impression: No acute cardiopulmonary process. Findings: A portable erect frontal chest radiograph again demonstrates multiple sternal\n wires, which are intact. Heart size remains mildly enlarged. The lungs are\n fairly well-aerated, without focal consolidation, pleural effusion, or\n pneumothorax. The visualized upper abdomen is unremarkable.",
"image_path": [
"p16/p16957952/s50482541/63f854b9-c24c2a15-3c4ee54e-72c08c57-5b8bcf18.jpg"
],
"split": "test"
},
{
"id": "962a470a-df0275b5-6b8e2125-e3cc9c90-bf7e0a66",
"study_id": 54300688,
"subject_id": 10933609,
"report": "impression: Stable appearance of the chest. Findings: The cardiac, mediastinal, and hilar contours appear unchanged. \n Multifocal opacities which persist in the upper lungs with volume loss suggest\n chronic scarring without definite superimposed disease. Blunting of the left\n posterior costophrenic sulcus is unchanged, suggesting either trace pleural\n effusion or pleural thickening. Bony structures are unremarkable.",
"image_path": [
"p10/p10933609/s54300688/962a470a-df0275b5-6b8e2125-e3cc9c90-bf7e0a66.jpg"
],
"split": "test"
},
{
"id": "7a238738-8c621632-91033197-65bce15b-74461a6c",
"study_id": 51584806,
"subject_id": 19800337,
"report": "impression: No acute cardiopulmonary process. Findings: PA and lateral views of the chest are compared to previous exam\n from ___. The lungs are now clear without focal consolidation or\n effusion. Cardiomediastinal silhouette is normal. Osseous and soft tissue\n structures are unremarkable.",
"image_path": [
"p19/p19800337/s51584806/7a238738-8c621632-91033197-65bce15b-74461a6c.jpg"
],
"split": "test"
},
{
"id": "b9850dc4-c0036cbc-c577eb21-c259db2c-2d9368a6",
"study_id": 53138800,
"subject_id": 14353044,
"report": "As compared to the previous radiograph, there is no relevant\n change. Status post spinal stabilization, left subclavian access line. \n Borderline size of the cardiac silhouette, elevation of the right\n hemidiaphragm with subsequent areas of atelectasis seen on both the frontal\n and the lateral radiograph. No newly appeared parenchymal opacities. No\n larger pleural effusions.",
"image_path": [
"p14/p14353044/s53138800/b9850dc4-c0036cbc-c577eb21-c259db2c-2d9368a6.jpg"
],
"split": "test"
},
{
"id": "58081a4f-fb575b5b-d178ec1c-b8b6a415-24868cdf",
"study_id": 53567752,
"subject_id": 14387068,
"report": "impression: Slight interval decrease in size of right-sided pneumothorax;\n however, interval enlargement of the right-sided pleural effusion. Stable\n mild leftward deviation of the cardiomediastinal silhouette. Findings: AP and lateral views of the chest were compared to previous exam\n ___ ___.\n \n When compared to prior, previously seen right-sided pneumothorax is slightly\n smaller. There has, however, been interval enlargement of the right-sided\n pleural effusion. Slight leftward deviation of the mediastinum is unchanged. \n The left lung remains clear. The cardiomediastinal contours are stable. The\n osseous and soft tissue structures are unremarkable.",
"image_path": [
"p14/p14387068/s53567752/58081a4f-fb575b5b-d178ec1c-b8b6a415-24868cdf.jpg"
],
"split": "test"
},
{
"id": "f2795cb8-461db7d5-3a023168-8b1300eb-d418d99f",
"study_id": 50792961,
"subject_id": 14841168,
"report": "impression: No focal consolidation concerning for pneumonia. Findings: Compared to the prior radiograph, lung volumes remain low. Streaky opacity in\n the left lung base is likely atelectasis, and similar to the prior radiograph.\n No focal opacity identified at the left lung base on concurrent CT. Moderate\n cardiomegaly is unchanged. The mediastinal and hilar contours are stable. No\n pneumothorax is identified.",
"image_path": [
"p14/p14841168/s50792961/f2795cb8-461db7d5-3a023168-8b1300eb-d418d99f.jpg"
],
"split": "test"
},
{
"id": "f0e11656-d359330e-8e7c2e5d-09c9d0d0-583da81f",
"study_id": 57137730,
"subject_id": 18615099,
"report": "impression: Tiny right pleural effusion. Findings: Single portable upright chest radiograph was obtained. Linear\n atelectasis at the right base is more discrete compared to prior exam. No\n consolidation, effusion or pneumothorax is present. Moderate cardiomegaly is\n stable. A tiny right effusion is noted. Surgical clips and sternotomy wires\n are intact. A left chest cardiac device has two leads in stable position.",
"image_path": [
"p18/p18615099/s57137730/f0e11656-d359330e-8e7c2e5d-09c9d0d0-583da81f.jpg"
],
"split": "test"
},
{
"id": "a6aacacb-72188cab-113e38f7-dc63b7cb-e0b3cd1a",
"study_id": 52072042,
"subject_id": 17257913,
"report": "As compared to the previous radiograph, there is no relevant\n change. Relatively wide mediastinum, caused by mediastinal lipomatosis\n (documented on a PET-CT examination from ___). Borderline size of\n the cardiac silhouette. No evidence of pleural effusion, pulmonary edema, or\n pneumonia. No pneumothorax.",
"image_path": [
"p17/p17257913/s52072042/a6aacacb-72188cab-113e38f7-dc63b7cb-e0b3cd1a.jpg"
],
"split": "test"
},
{
"id": "93795e56-ef882771-fa23c36d-bf8cf35b-fc41aadc",
"study_id": 54472974,
"subject_id": 13762730,
"report": "impression: Stable marked cardiomegaly without evidence of pulmonary edema. Findings: Cardiac silhouette is markedly enlarged, but stable in size, with\n indwelling right atrial and right ventricular pacing leads unchanged in\n position. The lungs are well expanded and grossly clear except for a small\n calcified granuloma at the left lung apex. There are no pleural effusions or\n acute skeletal findings.",
"image_path": [
"p13/p13762730/s54472974/93795e56-ef882771-fa23c36d-bf8cf35b-fc41aadc.jpg"
],
"split": "test"
},
{
"id": "bc25fa99-0d3766cc-7704edb7-5c7a4a63-dc65480a",
"study_id": 54280501,
"subject_id": 16043637,
"report": "impression: Relatively hyperinflated lungs, suggesting COPD. Possible minimal central\n pulmonary vascular engorgement without overt pulmonary edema. No focal\n consolidation. Mild cardiomegaly. Findings: The patient is status post median sternotomy. Left-sided pacer device is seen\n with leads extending to the expected positions of the right atrium and right\n ventricle. The cardiac silhouette is mildly enlarged. Mediastinal contours\n are unremarkable. There may be minimal central vascular engorgement without\n overt pulmonary edema. No large pleural effusion is seen. There is no evidence\n of pneumothorax or focal consolidation. The lungs appear relatively\n hyperinflated.",
"image_path": [
"p16/p16043637/s54280501/bc25fa99-0d3766cc-7704edb7-5c7a4a63-dc65480a.jpg"
],
"split": "test"
},
{
"id": "dda9463c-13653db6-03e65f74-74ef0b98-4cceb8c9",
"study_id": 58929044,
"subject_id": 10933609,
"report": "impression: Essentially complete resolution of the right upper lobe opacity\n seen on prior. Findings suggestive of underlying chronic upper lobe scarring,\n although superimposed acute infectious process, particularly on the left, is\n not completely excluded. Findings: PA and lateral views of the chest are compared to multiple prior\n exams including CT torso from ___ with most recent x-ray from ___.\n \n When compared to most recent exam, there has been near complete resolution of\n the right upper lung opacity. There is evidence of scarring at the upper\n lobes bilaterally with retraction of the hila and some nodular densities,\n particularly in the left upper lung. These have been seen on multiple prior\n exams. Minimal blunting of the left posterior costophrenic angle may\n represent trace effusion. There is no large confluent consolidation. \n Cardiomediastinal silhouette is stable as are the osseous structures, noting\n multiple orthopedic screws projecting over the right glenoid.",
"image_path": [
"p10/p10933609/s58929044/dda9463c-13653db6-03e65f74-74ef0b98-4cceb8c9.jpg"
],
"split": "test"
},
{
"id": "2ae8ec41-067f24d2-3f3ea6b7-113cb63b-aa3cc9e0",
"study_id": 59239338,
"subject_id": 10402372,
"report": "impression: Little change in the severe bronchiectasis and emphysema. Findings: In comparison with the study of ___, there is little overall\n change in the peribronchial thickening and impaction with extensive bibasilar\n bronchiectasis. This is again extremely well seen on the lateral radiograph. \n Hyperexpansion of the lungs is consistent with emphysema and the cardiac size\n is normal. No evidence of pulmonary edema.\n \n No evidence of acute focal pneumonia.",
"image_path": [
"p10/p10402372/s59239338/2ae8ec41-067f24d2-3f3ea6b7-113cb63b-aa3cc9e0.jpg"
],
"split": "test"
},
{
"id": "9ffe4a2c-7cf9a8f6-c97f630e-4618ae86-c49236fd",
"study_id": 56618763,
"subject_id": 18079481,
"report": "impression: Low lung volumes without acute findings. Findings: Lung volumes are low. No pleural effusion or pneumothorax is\n detected. Bibasilar atelectasis is present. There is mild left ventricular\n enlargement. Bilateral rib fractures are noted.",
"image_path": [
"p18/p18079481/s56618763/9ffe4a2c-7cf9a8f6-c97f630e-4618ae86-c49236fd.jpg"
],
"split": "test"
},
{
"id": "992ca7aa-bc9d75c5-cab8f375-a649cfc4-2472eda9",
"study_id": 59589248,
"subject_id": 13352405,
"report": "impression: Stable appearance of right-sided postoperative small apical\n pneumothorax and pleural effusion. Findings: PA and lateral chest views have been obtained with patient in\n upright position. Comparison is made with the next preceding portable AP\n single chest view of ___. Right-sided chest tube remains in place\n terminating somewhat lower than on the preceding study in the apical area. \n The second lower right chest tube remains in unchanged position. Small amount\n of right-sided pleural effusion persists blunting the lateral and posterior\n pleural sinus. No new parenchymal infiltrates are seen, and no significant\n pneumothorax has developed in the apical area. The left-sided hemithorax\n remains unchanged with no new infiltrates. As before, there are local rib\n deformities apparently related to previous old trauma as already observed on\n previous chest CT.",
"image_path": [
"p13/p13352405/s59589248/992ca7aa-bc9d75c5-cab8f375-a649cfc4-2472eda9.jpg"
],
"split": "test"
},
{
"id": "255f4674-83241c13-0d166114-1542f2fc-016ce9ee",
"study_id": 53302552,
"subject_id": 12952223,
"report": "In comparison with study of ___, there is extremely poor\n inspiration on the frontal view. Opacification at the bases most likely\n reflects pleural fluid and atelectasis. The pulmonary vascularity is\n difficult to assess, though there probably is some elevated pulmonary venous\n pressure.",
"image_path": [
"p12/p12952223/s53302552/255f4674-83241c13-0d166114-1542f2fc-016ce9ee.jpg"
],
"split": "test"
},
{
"id": "8ce5b932-2d8ffc38-cb498d1d-80d458cd-cec8ac86",
"study_id": 50801992,
"subject_id": 16672854,
"report": "impression: New bilateral hazy opacities with persistent moderate\n cardiomegaly. These findings are likely representative of moderate pulmonary\n edema due to congestive heart failure. Findings: moderate cardiomegaly persists. There are new diffuse bilateral\n hazy opacities suggestive of moderate increase in pulmonary central venous\n pressure. Mid sternotomy wires appear intact. Lungs are without focal\n consolidation. Bilateral small pleural effusions may be present. No acute\n fracture is identified.",
"image_path": [
"p16/p16672854/s50801992/8ce5b932-2d8ffc38-cb498d1d-80d458cd-cec8ac86.jpg"
],
"split": "test"
},
{
"id": "47168ca2-46fb63bc-f859ecb2-d1a48369-fbc2f3cf",
"study_id": 55499601,
"subject_id": 19389547,
"report": "In comparison with the study of ___, there is increased prominence\n of opacification adjacent to the right lateral chest wall. It is unclear\n whether this could merely reflect change in degree of obliquity of the patient\n or whether there is a reason to suggest increased fluid within the pleural\n space. The right hemidiaphragm remains sharp and there is nothing to indicate\n layering pleural effusion.\n \n This information has been telephoned to Dr. ___, ___ was covering for Dr.\n ___.",
"image_path": [
"p19/p19389547/s55499601/47168ca2-46fb63bc-f859ecb2-d1a48369-fbc2f3cf.jpg"
],
"split": "test"
},
{
"id": "8a2ac87e-67bd3fae-31632688-1d6dbc89-594ca350",
"study_id": 56917340,
"subject_id": 18512911,
"report": "impression: Increased opacity of right lower lung may reflect worsening\n atelectasis, though in proper clinical setting, pneumonia is a possibility. \n No pleural effusion evident. Findings: Chest PA and lateral radiograph demonstrates unremarkable mediastinal and\n hilar contours. Stable mild cardiomegaly evident. Increased opacity\n overlying the right diaphragm on background of right lower lung atelectasis,\n may indicate pneumonia. No pleural effusion or pneumothorax evident.\n Stable L1 and T12 compression fractures. Stable degenerative changes of the\n right shoulder.",
"image_path": [
"p18/p18512911/s56917340/8a2ac87e-67bd3fae-31632688-1d6dbc89-594ca350.jpg"
],
"split": "test"
},
{
"id": "702ea80d-45e751b9-f310cea5-80c50417-c80de945",
"study_id": 58039954,
"subject_id": 19182863,
"report": "impression: Stable bilateral layering pleural effusions with bibasilar airspace process\n likely reflecting compressive atelectasis. There has been interval appearance\n of mild interstitial and pulmonary edema. Left-sided pacer remains in place\n with the lead traversing a left superior vena cava to the right ventricular\n apex. Status post median sternotomy with mitral annular ring. No\n pneumothorax. Findings: PA and lateral views of the chest ___ at 12:55 are submitted.",
"image_path": [
"p19/p19182863/s58039954/702ea80d-45e751b9-f310cea5-80c50417-c80de945.jpg"
],
"split": "test"
},
{
"id": "08da513d-5325ee2d-d57746d8-762cf929-bf1c0fa4",
"study_id": 50682888,
"subject_id": 19404187,
"report": "impression: Interval decrease in size of left upper lobe opacity, possibly\n reflecting resolution of prior hemorrhage. Likely small left pleural\n effusion. Findings: Chest PA and lateral radiograph demonstrates decreased size of the\n left upper lobe opacity possibly due to resolution of hemorrhage, now\n measuring 2.8 in the craniocaudal dimension compared to 3.5 cm on prior study.\n There is persisitent if not increased streaky retrocardiac opacities, possibly\n related to aspiration. No definitive opacification concerning for pneumonia.\n Minimal left costophrenic angle blunting, likely represents small left pleural\n effusion. No osseous abnormalities identified.",
"image_path": [
"p19/p19404187/s50682888/08da513d-5325ee2d-d57746d8-762cf929-bf1c0fa4.jpg"
],
"split": "test"
},
{
"id": "f95e2c77-d318c10b-c5113c5d-455b870e-eb3878e8",
"study_id": 50425233,
"subject_id": 14992360,
"report": "There is no pleural effusion,\n pneumothorax or focal airspace consolidation. The cardiac silhouette is\n mildly enlarged. The aorta is tortuous and calcified. The pulmonary\n vascularity is normal. A linear opacity in the left mid lung is probably\n scarring from prior pneumonia demonstrated in this region. Parenchymal\n distortion and apical bullous changes are consistent with underlying\n emphysema. Bilateral pleural thickening is redemonstrated, most pronounced at\n the apices and right upper hemithorax laterally. No new areas of parenchymal\n consolidation are noted.\n \n A left-sided pacemaker is present with wires terminating in the right atrium\n and right ventricle. Degenerative changes are seen in the thoracic spine.",
"image_path": [
"p14/p14992360/s50425233/f95e2c77-d318c10b-c5113c5d-455b870e-eb3878e8.jpg"
],
"split": "test"
},
{
"id": "5f860da1-0df267dd-71c297f8-f5833732-c79b751d",
"study_id": 59286076,
"subject_id": 19028690,
"report": "impression: Low lung volumes, without pneumonia or CHF. Moderate cardiac\n enlargement is stable in appearance. Findings: There are low lung volumes without focal consolidation, effusion,\n or pneumothorax. The cardiac silhouette is moderately enlarged, there is\n stable widening of the mediastinum. Pulmonary vasculature appears normal.",
"image_path": [
"p19/p19028690/s59286076/5f860da1-0df267dd-71c297f8-f5833732-c79b751d.jpg"
],
"split": "test"
},
{
"id": "3433048d-a6c5dc75-1a99a0b6-1f89a734-ef0b39b8",
"study_id": 56680924,
"subject_id": 13135946,
"report": "Comparison is made to prior study from ___.\n \n There is a Swan-Ganz catheter whose distal lead tip is in the main pulmonary\n outflow tract. The cardiac silhouette is enlarged. There is again seen\n moderate right-sized pleural effusion which is stable. There is some\n improvement in the pulmonary vascular edema. There are no pneumothoraces\n identified.",
"image_path": [
"p13/p13135946/s56680924/3433048d-a6c5dc75-1a99a0b6-1f89a734-ef0b39b8.jpg"
],
"split": "test"
},
{
"id": "c7bb0e40-1f6e7506-544a2f87-79320653-743f3351",
"study_id": 50149345,
"subject_id": 19757720,
"report": "As compared to the previous radiograph, there is no relevant\n change. Diffuse increased opacity of the right lung, with several air\n bronchograms. A pre-existing right pleural effusion seems to have moderately\n decreased. No changes in the left lung. Unchanged monitoring and support\n devices. Unchanged aspect of the cardiac silhouette.",
"image_path": [
"p19/p19757720/s50149345/c7bb0e40-1f6e7506-544a2f87-79320653-743f3351.jpg"
],
"split": "test"
},
{
"id": "0ebfea17-388d6e3e-19b4850d-4da084f8-0088c1c3",
"study_id": 50453673,
"subject_id": 16826047,
"report": "impression: Right lower lobe pneumonia with probable right subpulmonic\n effusion. Findings: Swan-Ganz catheter has been removed, and a\n right-sided Port-A-Cath is noted with tip in the lower SVC. Consolidative\n opacity within the right lower lobe is concerning for pneumonia. There is\n elevation of the right hemidiaphragm with lateralization of the diaphragmatic\n peak suggesting a subpulmonic effusion. The cardiac silhouette size is top\n normal. There is mild prominence of the pulmonary vascular markings. No\n left-sided pleural effusion is seen, and there is no pneumothorax. There are\n no acute osseous abnormalities.",
"image_path": [
"p16/p16826047/s50453673/0ebfea17-388d6e3e-19b4850d-4da084f8-0088c1c3.jpg"
],
"split": "test"
},
{
"id": "e38221a2-36d9eedb-5a9af804-2eba7cb0-ea8d7ffd",
"study_id": 54614605,
"subject_id": 17340686,
"report": "impression: New left central line. No pneumothorax. Findings: There is a new left subclavian line with tip at the cavoatrial junction. Lung\n volumes are low. The right lower lobe opacities unchanged. There continues to\n be cardiomegaly, pulmonary vascular redistribution, ill-defined vascularity,\n and retrocardiac opacity compatible with CHF. The NG tube and large bore right\n IJ line are unchanged. The ET tube is 2 cm above the Carina. There is no\n pneumothorax.",
"image_path": [
"p17/p17340686/s54614605/e38221a2-36d9eedb-5a9af804-2eba7cb0-ea8d7ffd.jpg"
],
"split": "test"
},
{
"id": "f2166859-f4629ed4-014033b5-930fc410-8a9f51c9",
"study_id": 58351865,
"subject_id": 17340686,
"report": "Frontal and lateral views of the chest were obtained. Double-lumen\n left-sided dialysis catheter is seen terminating in the right atrium, stable\n in position. There is stable enlargement of the cardiac silhouette. The\n aortic knob remains calcified. There is prominence of the pulmonary\n vasculature, similar to prior. There may be small bilateral pleural\n effusions. The lateral view is suboptimal due to patient's overlying arm and\n a posterior lung consolidation is not excluded. No evidence of pneumothorax.",
"image_path": [
"p17/p17340686/s58351865/f2166859-f4629ed4-014033b5-930fc410-8a9f51c9.jpg"
],
"split": "test"
},
{
"id": "1d1bc795-245a8bf2-267d7b91-209d78ab-a1e3f52f",
"study_id": 51836430,
"subject_id": 16848073,
"report": "There is no focal consolidation, pneumothorax or pneumomediastinum.\n Opacities at the bases are likely atelectasis. The cardiomediastinal\n silhouette is unremarkable.",
"image_path": [
"p16/p16848073/s51836430/1d1bc795-245a8bf2-267d7b91-209d78ab-a1e3f52f.jpg"
],
"split": "test"
},
{
"id": "7c90c07b-1bc26a56-953fb718-22a14ecc-13cba6ed",
"study_id": 51184012,
"subject_id": 14295224,
"report": "impression: Persistent right upper lobe ill-defined opacity has changed configuration\n compared to the prior study and may be reflective of recurrent pneumonia or\n aspiration.\n \n Change in interpretation from the preliminary to final report was communicated\n with Dr ___ ___ phone at ___ on ___ by ___ Findings: The lungs are hyperinflated and diaphragms are flattened. An ill-defined\n opacity in the right upper lobe is persists compared to ___, and\n has changed configuration slightly. An 8 mm right lower lobe pulmonary nodule\n is stable. A small right effusion or pleural thickening is unchanged. There\n is no pneumothorax. Cardiac and mediastinal contours are unchanged, and the\n patient is status post esophagectomy and gastric pull-through.",
"image_path": [
"p14/p14295224/s51184012/7c90c07b-1bc26a56-953fb718-22a14ecc-13cba6ed.jpg"
],
"split": "test"
},
{
"id": "fb85016a-bff648ee-d64f0e6d-8bf72ac1-ce274815",
"study_id": 58094975,
"subject_id": 18224196,
"report": "Since ___, right chest and mediastinal drain tubes have\n been removed. There is no appreciable pneumothorax. Left lower lung opacity\n obscuring the left cardiomediastinal border and the left lung base has\n minimally worsened since ___ and is combination of moderate left\n effusion and left lower lung atelectasis. Riight basal atelectasis and\n presumed small right pleural effusion is unchanged. There is no significant\n change in the upper mediastinal. Right internal jugular sheath has its tip\n ending at the upper SVC. There is evidence of prior median sternotomy and\n sternal sutures are intact.",
"image_path": [
"p18/p18224196/s58094975/fb85016a-bff648ee-d64f0e6d-8bf72ac1-ce274815.jpg"
],
"split": "test"
},
{
"id": "29a9ca2f-50292418-e78e2999-12755e18-3103a476",
"study_id": 50382515,
"subject_id": 16508811,
"report": "impression: Possible mild edema with superimposed pneumonia. Findings: In comparison with the most recent examination, lung volumes slightly lower. \n The cardiac silhouette is stably enlarged. Again noted is a mild\n indistinctness of the pulmonary vasculature with superimposed opacities\n bilaterally, more confluent on the left than previously noted, consistent with\n superimposed pneumonia.",
"image_path": [
"p16/p16508811/s50382515/29a9ca2f-50292418-e78e2999-12755e18-3103a476.jpg"
],
"split": "test"
},
{
"id": "1e7e7b71-9afe22dc-51aaf15b-79809a2a-bd5d192d",
"study_id": 50654010,
"subject_id": 16043637,
"report": "impression: 1. Right upper extremity PICC line terminates at the superior cavoatrial\n junction.\n 2. Stable cardiomegaly.\n 3. No definite evidence of pneumonia. Findings: Dual-chamber pacemaker and aortic valve are in stable position. Sternal wires\n are intact. Right upper extremity PICC line terminates at the superior\n cavoatrial junction. There is slight elevation of the right hemidiaphragm,\n and seen on prior studies. No definite parenchymal consolidation. No pleural\n effusion or pneumothorax. Heart size is mildly enlarged.",
"image_path": [
"p16/p16043637/s50654010/1e7e7b71-9afe22dc-51aaf15b-79809a2a-bd5d192d.jpg"
],
"split": "test"
},
{
"id": "1ed95e47-83a54489-79ebd823-db934045-acd7ca23",
"study_id": 58001075,
"subject_id": 18067737,
"report": "impression: Left upper lobe opacification with mild volume loss concerning\n for pneumonic consolidation and possibly post-obstructive pneumonitis\n associated with a new central mass, radiation stricture, or mucus plug. More\n central denser opacity may represent mass or particularly dense area of\n consolidation. CT is recommended to better assess if needed clinically,\n preferably with intravenous contrast if no contraindications exist. \n \n These findings were discussed with Dr. ___ at 3:30 p.m. on ___ by telephone. Findings: The right lung is clear. There is new diffuse patchy opacities\n throughout the left upper lobe and lingula. The left hemidiaphragm is\n slightly elevated. There is a more dense opacity compared to the prior study\n and is concerning for either a mass or more confluent consolidation. Prior\n radiation changes are also seen within the left lung. There is a small\n pleural effusion on the left. The mediastinal and cardiac contours on the\n left are blurred by superimposed lung opacification. The right mediastinal\n and hilar and cardiac contours are normal. Pacemaker is in place with\n biventricular leads in the appropriate position.",
"image_path": [
"p18/p18067737/s58001075/1ed95e47-83a54489-79ebd823-db934045-acd7ca23.jpg"
],
"split": "test"
},
{
"id": "9cc3281f-64ff9f26-d2f759b1-ee26296f-50d416d4",
"study_id": 57667161,
"subject_id": 16553329,
"report": "impression: Top normal heart size, tiny left effusion. Findings: AP upright and lateral views of the chest provided. There is top-normal heart\n size with tiny left pleural effusion. Calcified nodular structures in the left\n upper lung and right mid to lower lung likely represent calcified granulomas.\n There is no evidence of pneumonia or CHF. Mediastinal contour stable. Bony\n structures intact.",
"image_path": [
"p16/p16553329/s57667161/9cc3281f-64ff9f26-d2f759b1-ee26296f-50d416d4.jpg"
],
"split": "test"
},
{
"id": "6d864779-3ef443ae-59264dbd-d63f8a20-cf4aa1e5",
"study_id": 53025898,
"subject_id": 12847817,
"report": "impression: Slightly increased moderate to large right-sided pleural effusion with\n collapse of much of the right middle lobe and right lower lobe. Superimposed\n pneumonia cannot be excluded given the appropriate clinical circumstance. Findings: The heart size is moderately enlarged. The mediastinal silhouette and hilar\n contours are unchanged. A moderate to large right-sided pleural effusion is\n slightly increased in volume compared to prior examination with collapse of\n much of the right lower lobe and right middle lobe. There is also some\n consolidation at the base of the right upper lobe which could be due to\n compressive atelectasis. There is no left effusion. The upper lung zones\n appear clear. There is no pneumothorax.",
"image_path": [
"p12/p12847817/s53025898/6d864779-3ef443ae-59264dbd-d63f8a20-cf4aa1e5.jpg"
],
"split": "test"
},
{
"id": "fc2dd069-a9848695-2c9cc70c-cf06c0f6-38694917",
"study_id": 56858524,
"subject_id": 18487334,
"report": "impression: Mild cardiomegaly. No acute intrathoracic process. Findings: The lungs are low in volume but clear. The cardiac silhouette is possibly\n mildly enlarged. Low lung volumes may be responsible for mild widening of the\n mediastinal silhouette. The hilar contours and pleural surfaces are normal. \n No pleural effusion is present. A left-sided pacer terminates with its leads\n in the right atrium and right ventricle. Non-standard placement of the right\n atrial lead is unchanged.",
"image_path": [
"p18/p18487334/s56858524/fc2dd069-a9848695-2c9cc70c-cf06c0f6-38694917.jpg"
],
"split": "test"
},
{
"id": "0c0e3903-2f744a5c-3750bad4-6d772736-6bf1c8a2",
"study_id": 54899257,
"subject_id": 17763117,
"report": "impression: Stable chest findings, no evidence of new acute pneumonia. Findings: Patient's condition required examination in sitting upright position using AP\n frontal view and left lateral views. Comparison is made with the next\n preceding portable chest examination of ___. As before, there\n is status post sternotomy. Moderate cardiac enlargement is seen. Previously\n identified permanent pacer with dual intracavitary electrodes and ICD device\n in unchanged position. The same holds for the recently placed right-sided\n PICC line which is now seen to reach in the upper third of the right atrium. \n Moderate cardiac enlargement as before. No signs of acute CHF and no acute\n parenchymal infiltrates are present. Lateral and posterior pleural sinuses\n are free from any fluid accumulation.",
"image_path": [
"p17/p17763117/s54899257/0c0e3903-2f744a5c-3750bad4-6d772736-6bf1c8a2.jpg"
],
"split": "test"
},
{
"id": "a160eb01-5f36fb58-b0a04a57-1773448e-934b5036",
"study_id": 54232340,
"subject_id": 12736592,
"report": "impression: No relevant change from study 10 hours prior. Stable small right\n pleural effusion. Findings: Single frontal view of the chest was obtained. The heart is of\n normal size with stable cardiomediastinal contours. A small right pleural\n effusion is similar to the exam 10 hours prior. No focal consolidation or\n pneumothorax. There is small atelectasis at the right base. \n Chronic-appearing right rib fractures are similar to prior. Sternotomy wires\n and mediastinal clips are intact.",
"image_path": [
"p12/p12736592/s54232340/a160eb01-5f36fb58-b0a04a57-1773448e-934b5036.jpg"
],
"split": "test"
},
{
"id": "02ed59f0-43d0aa6f-4bf3340b-c891b4b8-42ea5f9b",
"study_id": 59862902,
"subject_id": 13475033,
"report": "impression: Cardiomegaly and interstitial opacities, likely due to interstitial edema. If\n the diagnosis is in doubt clinically, followup radiographs after diuresis may\n be helpful to exclude the possibility of an atypical interstitial pneumonia. Findings: Bilateral interstitial opacities likely represent interstitial edema. There\n is no new focal consolidation, pleural effusion, or pneumothorax. \n Cardiomegaly persists. The mediastinal and hilar contours are unchanged. \n Leftward scoliosis of the thoracic size stable.",
"image_path": [
"p13/p13475033/s59862902/02ed59f0-43d0aa6f-4bf3340b-c891b4b8-42ea5f9b.jpg"
],
"split": "test"
},
{
"id": "fae734b5-cdbcad8f-13e2fcaf-8e2731ff-ca43dfa9",
"study_id": 55874928,
"subject_id": 15094735,
"report": "impression: 1. Possible right lower lobe pneumonia.\n 2. Increasing volume overload. Findings: Right dialysis catheter again terminates in the mid right atrium. \n Lungs are overinflated, with biapical hyperlucency. There is new right lower\n lobe opacity with obscuration of the hemidiaphragm. Increasing volume\n overload with mild cardiomegaly, central venous congestion, and\n interstitial/early airspace pulmonary edema. Probable small left effusion. \n CABG changes are noted, with median sternotomy wires and mediastinal clips.",
"image_path": [
"p15/p15094735/s55874928/fae734b5-cdbcad8f-13e2fcaf-8e2731ff-ca43dfa9.jpg"
],
"split": "test"
},
{
"id": "4639cd47-e73a89d3-48315552-a87979a8-7dd4f191",
"study_id": 55670303,
"subject_id": 12538508,
"report": "Sternotomy wires are unchanged. The heart and mediastinal contours\n are within normal limits and stable. There has been interval decrease in a\n left-sided pleural effusion with some persisting left basilar atelectasis. \n The right lung is clear. A line between the posterior aspects of the left\n third and fourth rib space is more compatible with a skin fold rather than the\n visceral pleura of the lung, so pneumothorax is not favored. However, given\n the recent instrumentation, if growing clinical concern for pneumothorax\n exists, short-interval followup may be considered.",
"image_path": [
"p12/p12538508/s55670303/4639cd47-e73a89d3-48315552-a87979a8-7dd4f191.jpg"
],
"split": "test"
},
{
"id": "84ffb901-893b00a7-7f2090be-d5cf6a4e-c34ab763",
"study_id": 55198163,
"subject_id": 17189198,
"report": "impression: Moderate pulmonary edema, cardiac silhouette enlargement, and\n pleural effusions suggest CHF. No evidence of lobar pneumonia. Findings: Frontal and lateral chest radiographs demonstrate moderate\n interstitial pulmonary edema. The heart size is moderately enlarged, there\n are moderate bilateral pleural effusion. There is no lobar consolidation. \n The aortic contour is mildly tortuous. Embolic coiling material is seen in\n the mid abdomen on the lateral view.",
"image_path": [
"p17/p17189198/s55198163/84ffb901-893b00a7-7f2090be-d5cf6a4e-c34ab763.jpg"
],
"split": "test"
},
{
"id": "146e8390-fd657795-492c6a0b-7aaa1bef-06c08c00",
"study_id": 59503672,
"subject_id": 11052935,
"report": "impression: Increased interstitial markings at the left lung base,\n potentially due to chronic changes; however, in the proper clinical setting,\n component of infection is also possible. Two views of the chest may help\n further characterize. Findings: Single portable view of the chest is compared to previous exam from\n ___. As on prior, the lungs are hyperinflated with parenchymal\n changes suggestive of emphysema, particularly at the left lung apex. \n Increased interstitial markings are identified at the left lung base. \n Elsewhere, the lungs are grossly clear. Cardiomediastinal silhouette is\n within normal limits. Osseous and soft tissue structures are unremarkable. \n Linear patchy at the right lung base is compatible with atelectasis versus\n scarring.",
"image_path": [
"p11/p11052935/s59503672/146e8390-fd657795-492c6a0b-7aaa1bef-06c08c00.jpg"
],
"split": "test"
},
{
"id": "ac58123d-32acfa38-3c734ace-8ef59986-fcca19ef",
"study_id": 57330459,
"subject_id": 12699874,
"report": "impression: Significantly increased partly subpulmonic right pleural effusion\n since prior exam.\n \n These findings were discussed with Dr. ___ by Dr. ___ ___\n telephone on ___ at 12:10 p.m. Findings: Since the prior radiograph, there has been substantial increase in\n the right pleural effusion that is partly subpulmonic. The lungs are\n otherwise clear. There is no focal consolidation or pneumothorax. Heart size\n is top normal. Mediastinal silhouette is unremarkable.",
"image_path": [
"p12/p12699874/s57330459/ac58123d-32acfa38-3c734ace-8ef59986-fcca19ef.jpg"
],
"split": "test"
},
{
"id": "ed9e09e7-e22ee204-4a73ca03-dc121d89-5ca5a446",
"study_id": 53225437,
"subject_id": 12530259,
"report": "impression: The exam is stable since ___ with expected changes after left\n lower lobe lobectomy. Findings: The patient had left lower lobe lobectomy in ___. Expected stable\n surgical changes are seen in the left lung with volume loss and mild pleural\n thickening. There is no pneumothorax. The right lung is unremarkable. \n Mediastinal and cardiac contours are not enlarged.",
"image_path": [
"p12/p12530259/s53225437/ed9e09e7-e22ee204-4a73ca03-dc121d89-5ca5a446.jpg"
],
"split": "test"
},
{
"id": "c768ecd2-dec91075-b6e6d204-6a9d0da8-e1ce939a",
"study_id": 50545797,
"subject_id": 17962324,
"report": "impression: Pulmonary vascular congestion without overt edema or focal consolidation. Findings: The lungs are hyperinflated but clear of focal consolidation. There is\n relative increased lucency in the right upper lung which is similar compared\n to prior. Elsewhere, interstitial markings are somewhat more prominent when\n compared to prior suggesting pulmonary vascular congestion. There is no focal\n consolidation suspicious for pneumonia nor pleural effusion. Cardiac\n silhouette is moderately enlarged. Median sternotomy wires and mediastinal\n clips are noted. No acute osseous abnormalities.",
"image_path": [
"p17/p17962324/s50545797/c768ecd2-dec91075-b6e6d204-6a9d0da8-e1ce939a.jpg"
],
"split": "test"
},
{
"id": "a2958de9-3f5b2b3e-0f868adb-1bfb09df-e2f90c3e",
"study_id": 55266015,
"subject_id": 15541869,
"report": "impression: Large hiatal hernia. Multifocal atelectasis and small pleural\n effusions. Findings: Cardiomediastinal contours are stable in appearance with persistent\n very large hiatal hernia. Linear areas of atelectasis are present in both mid\n lung regions, and atelectasis is also identified in the lower lungs adjacent\n to the large hiatal hernia. No areas of consolidation are evident. Small\n pleural effusions are present bilaterally. Bones are diffusely demineralized,\n and multilevel compression deformities are present, most marked at the\n thoracolumbar junction and upper lumbar region, with similar appearance in the\n thoracic spine to recent CT of ___. The patient is status post\n vertebroplasty procedures in the upper lumbar spine.",
"image_path": [
"p15/p15541869/s55266015/a2958de9-3f5b2b3e-0f868adb-1bfb09df-e2f90c3e.jpg"
],
"split": "test"
},
{
"id": "c375e421-68a1e118-133cd727-71b1be6f-8d62fa58",
"study_id": 53339862,
"subject_id": 11673948,
"report": "impression: No acute intrathoracic process Findings: AP portable upright view of the chest. Overlying ekg leads are present. \n Minimal platelike left basal atelectasis is noted. Otherwise lungs are clear\n without focal consolidation, effusion or pneumothorax. No signs of congestion\n or edema. The cardiomediastinal silhouette is normal. Imaged osseous\n structures are intact.",
"image_path": [
"p11/p11673948/s53339862/c375e421-68a1e118-133cd727-71b1be6f-8d62fa58.jpg"
],
"split": "test"
},
{
"id": "cfc2ef1b-a194024a-6147d0d3-6d42379a-575c395f",
"study_id": 52078894,
"subject_id": 14312560,
"report": "impression: No significant interval change. Findings: Frontal and lateral views of the chest were obtained. There are\n relatively low lung volumes. Mild elevation of the right hemidiaphragm\n persists. There is persistent right base atelectasis. No new focal\n consolidation is seen. There is no pleural effusion or pneumothorax. The\n cardiac and mediastinal silhouettes are unremarkable.",
"image_path": [
"p14/p14312560/s52078894/cfc2ef1b-a194024a-6147d0d3-6d42379a-575c395f.jpg"
],
"split": "test"
},
{
"id": "9189763d-c3b6ee12-d0d89f14-29a0cb1f-e3dee331",
"study_id": 54849848,
"subject_id": 10886362,
"report": "impression: No significant interval changes during the last 24 hours\n interval. The described changes with postoperative status, CHF, pleural\n effusion and intra-aortic balloon pump device in place is of course compatible\n with the patient's hypoxia. Findings: AP single view of the chest has been obtained with patient in\n sitting semi-upright position. Comparison is made with the next preceding\n portable chest examination with the patient in supine position as of ___. Again noted is status post sternotomy and significant enlargement of\n the cardiac silhouette. Previously described permanent pacer in left axillary\n position with two intracavitary electrodes in unchanged location. Unchanged\n position of left internal jugular approach central venous line terminating in\n upper portion of SVC. No pneumothorax has developed. Diffuse haze over both\n lung bases as before obliterating the diaphragmatic contours and indicative of\n bilateral pleural effusions partially layering posteriorly. The pulmonary\n venous congestive pattern persists. An intra-aortic balloon pump device is\n seen to terminate in the descending thoracic aorta about 3 cm below the level\n of the lower thoracic arch contour. This is unchanged.",
"image_path": [
"p10/p10886362/s54849848/9189763d-c3b6ee12-d0d89f14-29a0cb1f-e3dee331.jpg"
],
"split": "test"
},
{
"id": "5dfffffd-68cbd012-f3428c65-ebd2ffd8-57793a0c",
"study_id": 51844819,
"subject_id": 14851532,
"report": "impression: 1. Increased mild pulmonary vascular congestion from ___ with small right\n pleural effusion and right basilar atelectasis. Right basilar opacity may be\n combination of above, but underlying consolidation due to infection is not\n excluded.\n 2. Staple, suture material and scar in the left upper-to-mid lung. Findings: The lungs appear hyperexpanded. There is mild increased pulmonary\n vascular congestion from ___. A small right pleural effusion is likely\n present with mild right basilar atelectasis. Right base consolidation is not\n entirely excluded. No significant left pleural effusion or pneumothorax is\n detected. Suture chain material and scarring in the left upper-to-mid lung\n zone is not significantly changed. Multiple mediastinal surgical clips are\n compatible with history of CABG surgery. The cardiac silhouette is top normal\n in size but unchanged. The mediastinal and hilar contours are within normal\n limits with moderate tortuosity of the descending thoracic aorta. Lobulation\n at the apex of the left hemi thorax along the mediastinal border is stable,\n residual of slowly resolving hematoma.",
"image_path": [
"p14/p14851532/s51844819/5dfffffd-68cbd012-f3428c65-ebd2ffd8-57793a0c.jpg"
],
"split": "test"
},
{
"id": "c9fff184-4c819069-e151edf5-6591caae-9a76e8f0",
"study_id": 52606958,
"subject_id": 13475033,
"report": "impression: Moderate to severe interstitial pulmonary edema is worse compared with ___. Findings: PA and lateral chest radiographs were obtained. Diffuse interstitial\n opacities have progressed since ___. The hila are indistinct. There\n is a new small left pleural effusion. Moderate cardiomegaly is similar. \n Aortic arch calcifications are similar. There is a stable convex left\n thoracic scoliosis. Thoracic vertebral compression fractures and old left\n clavicle fracture are unchanged.",
"image_path": [
"p13/p13475033/s52606958/c9fff184-4c819069-e151edf5-6591caae-9a76e8f0.jpg"
],
"split": "test"
},
{
"id": "4dd16b7e-2f2d14a6-589fa0e3-f24d8230-874d3c21",
"study_id": 59440363,
"subject_id": 16043637,
"report": "impression: No acute abnormalities identified to explain patient's cough and asthma flare. Findings: The heart size is normal. The hilar and mediastinal contours are\n unremarkable. The lungs are well expanded and clear. The patient is status\n post median sternotomy with aortic valve repair. There is a pacer with the\n leads terminating appropriately in the right atrium and right ventricle. \n There is an aortic valve prosthesis. There is no pleural effusion or\n pneumothorax. There are no focal consolidations.",
"image_path": [
"p16/p16043637/s59440363/4dd16b7e-2f2d14a6-589fa0e3-f24d8230-874d3c21.jpg"
],
"split": "test"
},
{
"id": "4a834d65-3c7a5557-474061e3-4903563c-7ac8bfb4",
"study_id": 55610892,
"subject_id": 13473495,
"report": "impression: Pulmonary edema is slightly worse than on recent exam. Findings: Low lung volumes are again noted. There are however persistently increased\n interstitial markings which appear slightly progressed compared to prior. \n There is no pleural effusion. The cardiac silhouette is enlarged, as on prior.\n Left subclavian stent is again seen.",
"image_path": [
"p13/p13473495/s55610892/4a834d65-3c7a5557-474061e3-4903563c-7ac8bfb4.jpg"
],
"split": "test"
},
{
"id": "469b6bc3-cd9c3a49-238f4c5d-38cce895-b225e937",
"study_id": 55255832,
"subject_id": 11893091,
"report": "impression: Unchanged lead positions from recently inserted dual-chamber pacemaker. Findings: The lead positions of the dual-chamber pacemaker is unchanged\n compared to the prior exam. There is moderate cardiomegaly. The lungs\n demonstrate moderate pulmonary edema but no evidence of pleural effusions or\n pneumothorax. Mild atelectatic changes at the lung bases are unchanged.\n Incidental note is made of chronic stable calcified scarring in the left apex.\n There are no new parenchymal opacities. There is no evidence of pneumothorax.",
"image_path": [
"p11/p11893091/s55255832/469b6bc3-cd9c3a49-238f4c5d-38cce895-b225e937.jpg"
],
"split": "test"
},
{
"id": "e4e0e4ff-71138eac-7cef38bd-ce820887-d59037ff",
"study_id": 54218896,
"subject_id": 12303667,
"report": "impression: Diffuse interstitial abnormalities, small nodules, with no\n appreciable progression. Improved lung volumes. Findings: The cardiomediastinal and hilar contours are normal. There is no\n pleural effusion or pneumothorax. Lung volumes are increased compared to the\n most recent prior study. Diffuse interstitial abnormality with small nodules\n not significantly changed. Pulmonary vasculature is within normal limits.",
"image_path": [
"p12/p12303667/s54218896/e4e0e4ff-71138eac-7cef38bd-ce820887-d59037ff.jpg"
],
"split": "test"
},
{
"id": "cbe3bc41-e94a672f-5fdd94a6-aa2446b0-e821a444",
"study_id": 56116675,
"subject_id": 16435402,
"report": "impression: In the region of the known lingular mass, there is a persistent opacity\n measuring approximately 6.2 x 5.0 cm which is decreased in comparison to the\n postbiopsy opacity noted in ___ but greater than expected for\n postoperative hemorrhage at this time; thus raising suspicion for a possible\n infectious process.\n \n These findings were discussed by Dr. ___ with Dr. ___ ___ telephone at\n 11:42 am on ___. Findings: In the region of the lingular mass, there is a persistent opacity measuring\n approximately 6.2 x 5.0 cm and decreased in comparison to the postbiopsy\n opacity noted in ___ but greater than expected for postoperative\n hemorrhage at this time and thus raising suspicion for a possible infectious\n process. Otherwise, the right lung is clear. Mediastinal and cardiac\n silhouettes appears normal. Osseous structures are grossly unremarkable.",
"image_path": [
"p16/p16435402/s56116675/cbe3bc41-e94a672f-5fdd94a6-aa2446b0-e821a444.jpg"
],
"split": "test"
},
{
"id": "54035728-03eb01c3-1af39698-5f789e6f-686ca166",
"study_id": 59450064,
"subject_id": 19150427,
"report": "As compared to the previous radiograph, there is increasing\n pulmonary edema that is now mild-to-moderate in extent. In addition,\n atelectatic changes are seen at both lung bases as well as at the bases of the\n right upper lobe. Status post CABG. The lateral radiograph shows\n mild-to-moderate pleural effusion. No pneumonia.",
"image_path": [
"p19/p19150427/s59450064/54035728-03eb01c3-1af39698-5f789e6f-686ca166.jpg"
],
"split": "test"
},
{
"id": "f762fbc6-ca1926fb-06f3ef2a-b996a151-66a3b743",
"study_id": 54759244,
"subject_id": 13448574,
"report": "impression: No acute cardiopulmonary process. No displaced rib fracture seen. Findings: Frontal and lateral views of the chest and 2 additional views of the\n left-sided ribs were obtained. A BB marker projects over the lateral ninth\n and ___ left ribs indicating patient's site of concern. No displaced\n fracture is seen. The lungs are clear without focal consolidation. No\n pleural effusion or pneumothorax is seen. The cardiac and mediastinal\n silhouettes are unremarkable. There may be very minimal left basilar linear\n atelectasis/scarring.",
"image_path": [
"p13/p13448574/s54759244/f762fbc6-ca1926fb-06f3ef2a-b996a151-66a3b743.jpg"
],
"split": "test"
},
{
"id": "2f8ca5e2-5a1e02ab-e84f7547-069743e9-0f08d9e0",
"study_id": 57765703,
"subject_id": 10268877,
"report": "impression: 1. Unchanged bibasilar opacities are consistent with atelectasis or\n consolidation and pneumonia should be considered in the appropriate clinical\n context.\n 2. Improved pulmonary edema. Findings: Portable AP chest radiograph is obtained with the patient in the\n semi-erect position. Tracheostomy noted. Cardiomediastinal silhouette is\n unchanged; bulging of the pulmonary outflow tract reflects enlargement of\n pulmonary arteries and suggests underlying pulmonary arterial hypertension. \n Pulmonary edema has slightly improved compared to the prior study. Small\n right pleural effusion is unchanged. Again bibasilar opacifications are noted\n and are suggestive of atelectasis or consolidation.",
"image_path": [
"p10/p10268877/s57765703/2f8ca5e2-5a1e02ab-e84f7547-069743e9-0f08d9e0.jpg"
],
"split": "test"
},
{
"id": "bfb7a467-e88452aa-9ca0804d-6b66419b-ebbeec35",
"study_id": 59108077,
"subject_id": 13896515,
"report": "impression: Interval development of moderate pulmonary edema, compatible with\n cardiac decompensation. Findings: Portable upright chest radiograph demonstrates interval decrease in\n lung volumes, and interval development of moderate alveolar and interstitial\n pulmonary edema. There are no definite effusions. There is no pneumothorax. \n The cardiac silhouette remains mildly enlarged. Calcification of the aortic\n knob is unchanged.",
"image_path": [
"p13/p13896515/s59108077/bfb7a467-e88452aa-9ca0804d-6b66419b-ebbeec35.jpg"
],
"split": "test"
},
{
"id": "d9cc9107-872f0471-6fba0396-edc86cf6-6e1a2a4e",
"study_id": 52937624,
"subject_id": 15131736,
"report": "impression: Low lung volumes with probable bibasilar atelectasis. Infection at the lung\n bases cannot be excluded in the correct clinical setting. Mild pulmonary\n vascular congestion and trace left pleural effusion. Findings: Exam is limited by patient positioning as well as the patient's chin and neck\n obscuring the lung apices. Low lung volumes are present. Heart size is\n moderately enlarged. Atherosclerotic calcifications are noted at the aortic\n knob. Mediastinal contours are unremarkable. Crowding of bronchovascular\n structures is present with possible mild pulmonary vascular congestion. Small\n left pleural effusion is likely present. Patchy bibasilar opacities may\n reflect atelectasis. No large pneumothorax is present. There are\n hypertrophic changes noted in the thoracic spine.",
"image_path": [
"p15/p15131736/s52937624/d9cc9107-872f0471-6fba0396-edc86cf6-6e1a2a4e.jpg"
],
"split": "test"
},
{
"id": "6e2797cc-f1c60fb3-30a651cc-c23cf3d1-b15803bb",
"study_id": 57258004,
"subject_id": 19907884,
"report": "impression: No acute cardiopulmonary abnormality. Findings: Cardiac silhouette size is normal. The mediastinal and hilar contours are\n unremarkable. The pulmonary vasculature is not engorged. No focal\n consolidation, pleural effusion or pneumothorax is detected. Elevation of the\n right hemidiaphragm is unchanged. Multiple clips are again noted in the right\n paramediastinal region.",
"image_path": [
"p19/p19907884/s57258004/6e2797cc-f1c60fb3-30a651cc-c23cf3d1-b15803bb.jpg"
],
"split": "test"
},
{
"id": "f2a7f664-bfff0efe-5bb44ad4-469f58a4-0e6b7892",
"study_id": 54211038,
"subject_id": 12185775,
"report": "impression: Appropriately placed ET tube. Moderate pulmonary edema.\n \n These findings were reported to Dr. ___ at 4:55 p.m. via phone by\n ___. Findings: New endotracheal tube is seen appropriately positioned terminating\n no less than 2.5 cm above the carina. There are low lung volumes bilaterally\n with moderate pulmonary edema . Small quantity of bilateral pleural effusion\n is seen. Cardiomediastinal silhouette is somewhat obscured but is stable and\n within normal limits.",
"image_path": [
"p12/p12185775/s54211038/f2a7f664-bfff0efe-5bb44ad4-469f58a4-0e6b7892.jpg"
],
"split": "test"
},
{
"id": "60c60c6e-1471b41d-d8ae011a-299592ea-7c39d5e7",
"study_id": 50301215,
"subject_id": 10886362,
"report": "The endotracheal tube is too high, at the thoracic inlet. This\n finding was called to the CCU nurse, ___ at 5:00 p.m. at the time of\n dictating this report by Dr. ___. Otherwise, the appearance of the lungs\n is unchanged. Pacemaker and left IJ line are unchanged.",
"image_path": [
"p10/p10886362/s50301215/60c60c6e-1471b41d-d8ae011a-299592ea-7c39d5e7.jpg"
],
"split": "test"
},
{
"id": "d20291fc-8d626aa2-b3b2ef02-6f8b81ac-12f2432d",
"study_id": 53462705,
"subject_id": 12185775,
"report": "impression: 1. Resolution of bilateral pleural effusions.\n 2. Heart size remains enlarged. This could be indicative of cardiomyopathy\n or a pericardial effusion. Findings: There has been interval removal of a right-sided PICC line. The\n cardiac silhouette remains enlarged. There has been resolution of bilateral\n pleural effusions. Again visualized are two calcified left upper lobe\n granulomas.",
"image_path": [
"p12/p12185775/s53462705/d20291fc-8d626aa2-b3b2ef02-6f8b81ac-12f2432d.jpg"
],
"split": "test"
},
{
"id": "d2dc716d-a9421294-0f30f0db-ef17232a-0cb5f249",
"study_id": 57977763,
"subject_id": 13881772,
"report": "impression: No acute cardiopulmonary process. Findings: Frontal and lateral views of the chest were obtained. The lungs\n are hyperinflated/well expanded. Costochondral calcification is noted. No\n definite focal consolidation is seen. There is no pleural effusion or\n pneumothorax. The cardiac and mediastinal silhouettes are stable.",
"image_path": [
"p13/p13881772/s57977763/d2dc716d-a9421294-0f30f0db-ef17232a-0cb5f249.jpg"
],
"split": "test"
},
{
"id": "6c0daac8-adefbe30-1a6a00e7-ac963bb6-fc69e8e4",
"study_id": 57988903,
"subject_id": 16508811,
"report": "impression: 1. Retrocardiac opacity concerning for pneumonia.\n 2. Hilar congestion. Findings: Right IJ access dialysis catheter again noted with its tip in the region of\n the right atrium. Increased retrocardiac opacity raises concern for\n pneumonia. Findings appear progressed from prior exam. The heart size is\n stable. No pneumothorax or pleural effusion. Mediastinal contour unchanged. \n Hilar congestion again noted.",
"image_path": [
"p16/p16508811/s57988903/6c0daac8-adefbe30-1a6a00e7-ac963bb6-fc69e8e4.jpg"
],
"split": "test"
},
{
"id": "4b842f9a-e380a620-f62f355a-f706be25-95150ec3",
"study_id": 55736427,
"subject_id": 10933609,
"report": "impression: Worsening multifocal opacities concerning for pneumonia. Probable mild\n pulmonary vascular congestion. Low lung volumes. Findings: Lung volumes are reduced. The left internal jugular central venous catheter\n has been removed. The heart size is borderline enlarged, but accentuated due\n to low inspiratory lung volumes. There is crowding of the bronchovascular\n structures with probable mild pulmonary vascular congestion. Worsening\n consolidative opacity in the right upper lung field as well as focal opacities\n within the left upper and bilateral lower lung fields are concerning for\n multifocal pneumonia. No pleural effusion or pneumothorax is seen. No acute\n osseous abnormalities visualized. Clips are demonstrated within the left\n upper quadrant of the abdomen.",
"image_path": [
"p10/p10933609/s55736427/4b842f9a-e380a620-f62f355a-f706be25-95150ec3.jpg"
],
"split": "test"
},
{
"id": "f3c65ae4-81c03654-c3fe857f-dec24a17-a5a118b9",
"study_id": 50492868,
"subject_id": 18487334,
"report": "impression: The feeding tube extends below the level the diaphragms but beyond the field\n of view of this radiograph, likely however within the distal stomach. No other\n significant interval change since the prior radiograph. Findings: The feeding tube extends below the level of the diaphragms but beyond the\n field of view of this radiograph, likely within the distal stomach. A left\n chest wall dual lead pacemaker is present. The tip of the right PICC line\n extends to the level of the mid SVC.\n \n No focal consolidation, pleural effusion or pneumothorax identified. The size\n and appearance of the cardiomediastinal silhouette is unchanged.",
"image_path": [
"p18/p18487334/s50492868/f3c65ae4-81c03654-c3fe857f-dec24a17-a5a118b9.jpg"
],
"split": "test"
},
{
"id": "1479bd69-820c7589-5e02e82e-b713275f-99aed79d",
"study_id": 55336208,
"subject_id": 16751749,
"report": "There is moderate amount of right-sided subcutaneous emphysema\n which is similar in appearance compared to prior. Right-sided chest tube is\n again visualized. There is no increase in the pneumothorax. Bilateral\n parenchymal opacities are again visualized and not significantly changed. The\n tracheostomy tube is in standard location. Right subclavian line tip is in\n the mid SVC.",
"image_path": [
"p16/p16751749/s55336208/1479bd69-820c7589-5e02e82e-b713275f-99aed79d.jpg"
],
"split": "test"
},
{
"id": "0e20294a-a19790ed-687b001e-481e4273-f89dd2c4",
"study_id": 56951123,
"subject_id": 16662264,
"report": "impression: Lingular consolidation persists but continues to decrease in size\n as compared to the prior study. Findings: Frontal and lateral views of the chest were obtained. There\n remains small residual consolidation in the lingula, which continues to\n decrease in size as compared to the prior studies. No definite focal\n consolidation is seen on the right. There is no pleural effusion or\n pneumothorax. The cardiac and mediastinal silhouettes are stable and\n unremarkable.",
"image_path": [
"p16/p16662264/s56951123/0e20294a-a19790ed-687b001e-481e4273-f89dd2c4.jpg"
],
"split": "test"
},
{
"id": "bf73d8b0-3e093d0f-dd91f13c-0d6e276b-53136b54",
"study_id": 51511674,
"subject_id": 19150427,
"report": "impression: No acute cardiopulmonary process. Findings: Lungs are clear without focal consolidation, effusion, or edema. Mild\n cardiomegaly is similar compared to prior. Coronary artery stents and median\n sternotomy wires are noted. No acute osseous abnormalities.",
"image_path": [
"p19/p19150427/s51511674/bf73d8b0-3e093d0f-dd91f13c-0d6e276b-53136b54.jpg"
],
"split": "test"
},
{
"id": "3bb2cb54-60f696d8-9dfcbee7-5a506428-c7316197",
"study_id": 58581234,
"subject_id": 16855430,
"report": "impression: Finding suggestive of pulmonary vascular congestion with possible\n small bilateral pleural effusions. Findings: AP and lateral views of the chest are compared to previous exam\n from ___. Previously identified left PICC line is no longer seen. \n Lower lung volumes seen on the current exam. There are indistinct pulmonary\n vascular markings suggestive of fluid overload. There are also possible small\n bilateral pleural effusions noting that lateral view is limited secondary to\n patient's arms obscuring visualization. Cardiac silhouette is enlarged but\n stable. Degenerative changes noted at the acromioclavicular joints\n bilaterally.",
"image_path": [
"p16/p16855430/s58581234/3bb2cb54-60f696d8-9dfcbee7-5a506428-c7316197.jpg"
],
"split": "test"
},
{
"id": "63bc3ab0-da8f9dcb-006bcd2c-5af27843-de7a7597",
"study_id": 53417168,
"subject_id": 13606683,
"report": "impression: 1. Stable moderate cardiomegaly\n 2. Stable chronic parenchymal changes.\n 3. No evidence of acute pulmonary edema. Findings: An AP upright radiograph of the chest is provided. There is no\n significant change from the prior examination. Moderate cardiomegaly is\n stable. Chronic parenchymal opacities which are better demonstrated on the\n prior chest CT are also unchanged. There is no evidence of superimposed\n airspace opacification or pulmonary edema. There is no pneumothorax or\n pleural effusion. Median sternotomy cerclage wires are intact. The right\n pectoral AICD and its leads are unchanged.",
"image_path": [
"p13/p13606683/s53417168/63bc3ab0-da8f9dcb-006bcd2c-5af27843-de7a7597.jpg"
],
"split": "test"
},
{
"id": "b267e44d-493a0dca-420b4fd5-a91a1026-c3386cac",
"study_id": 54770541,
"subject_id": 15259244,
"report": "impression: Right internal jugular central venous catheter tip in the SVC. \n No interval change in mild pulmonary edema with continued left basilar\n consolidation possibly reflecting atelectasis or infection, with small\n bilateral pleural effusions. Findings: Right internal jugular central venous catheter\n tip terminates in the SVC. No pneumothorax is present. Patient is status\n post median sternotomy, CABG, and mitral valve repair. There is continued\n opacification of the left lung base. Small bilateral pleural effusions, left\n greater than right are again noted. There is mild pulmonary edema. Subacute\n left posterior third rib fracture is present. Streaky opacity in the right\n lung base may reflect atelectasis.",
"image_path": [
"p15/p15259244/s54770541/b267e44d-493a0dca-420b4fd5-a91a1026-c3386cac.jpg"
],
"split": "test"
},
{
"id": "04d8b146-8f27fd48-e07afc43-464529fc-57350e1b",
"study_id": 59480739,
"subject_id": 18615099,
"report": "impression: Left pleural effusion with overlying atelectasis. Left base\n opacity may be due to combination of pleural effusion and atelectasis,\n although consolidation is not excluded. Mild pulmonary vascular congestion. Findings: Frontal and lateral views of the chest are obtained. The patient\n is status post median sternotomy and CABG. Dual-lead left-sided pacemaker is\n again seen with leads extending to the expected positions of the right atrium\n and likely right ventricle. There is blunting of the left costophrenic angle\n most consistent with a small left pleural effusion. Left base opacity may be\n due to combination of pleural effusion and atelectasis, although consolidation\n is not excluded. There is mild central pulmonary vascular congestion. The\n cardiac silhouette is mildly enlarged. Mediastinal contours are similar\n compared to ___. There is diffuse osteopenia.",
"image_path": [
"p18/p18615099/s59480739/04d8b146-8f27fd48-e07afc43-464529fc-57350e1b.jpg"
],
"split": "test"
},
{
"id": "dd28d7b2-1303acd7-f23b52ab-4c24a9ab-f7296720",
"study_id": 54611996,
"subject_id": 16334516,
"report": "As compared to the previous radiograph, there is unchanged evidence\n of mild-to-moderate pulmonary edema. The pre-existing scars in the lung\n parenchyma, notably at the left lung apex and left lung base are constant in\n appearance. Constant size of the cardiac silhouette. No larger pleural\n effusions. The Dobbhoff catheter has been pulled back. The catheter is now\n malpositioned in the esophagus and needs to be advanced by at least 10cm to\n ensure position in the stomach. Unchanged position of the left PICC line. \n Unchanged alignment of the sternotomy wires.",
"image_path": [
"p16/p16334516/s54611996/dd28d7b2-1303acd7-f23b52ab-4c24a9ab-f7296720.jpg"
],
"split": "test"
},
{
"id": "1b3d4f71-68977c5e-a070ff6b-29584c84-b70bf667",
"study_id": 52793175,
"subject_id": 16043637,
"report": "impression: No acute cardiopulmonary process, unchanged compared to ___. Findings: PA and lateral views of the chest. A left-sided pacemaker is in\n appropriate position. Sternotomy wires again seen. An aortic valve\n replacement is again noted. Faint haziness over the lower lung fields\n bilaterally, likely from patient's body habitus. This is unchanged. There is\n no new focal consolidation, pleural effusion or pneumothorax. \n Cardiomediastinal and hilar contours are normal.",
"image_path": [
"p16/p16043637/s52793175/1b3d4f71-68977c5e-a070ff6b-29584c84-b70bf667.jpg"
],
"split": "test"
},
{
"id": "027b4660-9fc20c6a-35de711b-876f0690-f2fcb5a3",
"study_id": 52589781,
"subject_id": 14177219,
"report": "impression: Stable mild pulmonary vascular engorgement. Heart size is top\n normal. No evidence of pneumonia. Findings: PA and lateral views of the chest. There is stable mild pulmonary\n vascular engorgement. No evidence of pulmonary edema. There are no focal\n consolidations. No pneumothorax or pleural effusion. Heart size is top\n normal.",
"image_path": [
"p14/p14177219/s52589781/027b4660-9fc20c6a-35de711b-876f0690-f2fcb5a3.jpg"
],
"split": "test"
},
{
"id": "9870d11d-3a0d9c78-f49f71c6-58644dd5-ce1b85fb",
"study_id": 56129930,
"subject_id": 11052935,
"report": "impression: Left lower lobe pneumonia, more apparent than on ___. Findings: There is increased opacification in the left lung base with\n obscuration of the left hemidiaphragm when compared to ___. Again noted\n is hyperinflation and flattening of the diaphragms suggesting emphysema. The\n cardiomediastinal silhouette is within normal limits.",
"image_path": [
"p11/p11052935/s56129930/9870d11d-3a0d9c78-f49f71c6-58644dd5-ce1b85fb.jpg"
],
"split": "test"
},
{
"id": "39513708-faae323a-d74bc04a-b49a24ec-fbe051f6",
"study_id": 56605732,
"subject_id": 18570152,
"report": "impression: Mild cardiomegaly and central pulmonary vascular congestion. Findings: A left pectoral pacemaker is noted with a single intact lead. The heart is\n mildly enlarged. Mild central pulmonary vascular congestion is noted. \n Bibasilar airspace opacities likely reflect atelectasis. There is no lobar\n consolidation, large pleural effusion, or pneumothorax.",
"image_path": [
"p18/p18570152/s56605732/39513708-faae323a-d74bc04a-b49a24ec-fbe051f6.jpg"
],
"split": "test"
},
{
"id": "f12f4aff-464794a0-43804b4b-647ac047-cc14b671",
"study_id": 57032496,
"subject_id": 17340686,
"report": "Single AP semi-erect portable view of the chest was obtained. \n Moderate-to-severe pulmonary edema is again seen. Difficult to exclude\n underlying pleural effusions. The cardiac and mediastinal silhouettes are\n stable. There has been interval placement of a large-bore left-sided\n catheter, distal tip not optimally seen, but likely terminates in the\n cavoatrial junction/right atrium.",
"image_path": [
"p17/p17340686/s57032496/f12f4aff-464794a0-43804b4b-647ac047-cc14b671.jpg"
],
"split": "test"
},
{
"id": "711d6472-5ff3166e-7741ea62-00213982-c3a8a67b",
"study_id": 50211839,
"subject_id": 13881772,
"report": "impression: No acute cardiopulmonary process. Findings: The lungs are hyperinflated but clear of consolidation. Nodular opacities at\n the lung bases are compatible with nipple shadows as opposed to pulmonary\n nodules. Cardiac silhouette is unchanged. Mitral annular calcifications are\n again noted. Old healed left lower rib fractures are again noted",
"image_path": [
"p13/p13881772/s50211839/711d6472-5ff3166e-7741ea62-00213982-c3a8a67b.jpg"
],
"split": "test"
},
{
"id": "5e861703-66367757-f8a458b6-39741594-3ab89d41",
"study_id": 50020371,
"subject_id": 15758946,
"report": "impression: No acute cardiopulmonary process. Findings: Frontal and lateral views of the chest are obtained. Left-sided\n Port-A-Cath is again seen, terminating at the distal SVC/cavoatrial junction. \n Persistent blunting of the right costophrenic angle is seen. Chain sutures\n are again noted in the right mid lung. No new focal consolidation, large\n pleural effusion, or evidence of pneumothorax is seen. Cardiac and\n mediastinal silhouettes are stable, as are hilar contours. Old right rib\n deformity is again seen involving posterior right eighth rib. Known lesion in\n the right scapula is better assessed on CT.",
"image_path": [
"p15/p15758946/s50020371/5e861703-66367757-f8a458b6-39741594-3ab89d41.jpg"
],
"split": "test"
},
{
"id": "c9fec029-7cff7a68-c85274cf-7a560cce-becdcb7e",
"study_id": 50406925,
"subject_id": 13078497,
"report": "impression: Worsening, now severe, bilateral pulmonary edema. Supervening\n pneumonia can certainly not be excluded in the appropriate clinical setting.\n Interval removal of endotracheal tube. Cardiomediastinal silhouette stable. Findings: There has been an increase in the bilateral pulmonary edema status\n post extubation as evidenced by increased dense opacification, which is now\n nearly confluent consistent with severe pulmonary edema. The\n cardiomediastinal silhouette is difficult to evaluate given intervening\n pulmonary edema opacity, however appears unchanged. There is no pneumothorax.\n There has been complete obscuration of the costophrenic angles suggestive of\n bilateral pleural effusions. Right IJ catheter is unchanged in position and\n ends in the upper SVC. Sternotomy wires are unchanged in position, aligned\n along the midline with no evidence of sternal dehiscence.",
"image_path": [
"p13/p13078497/s50406925/c9fec029-7cff7a68-c85274cf-7a560cce-becdcb7e.jpg"
],
"split": "test"
},
{
"id": "f46ebce4-270dbbd9-24602b65-695b054c-bcd8093c",
"study_id": 51280998,
"subject_id": 12699874,
"report": "impression: Large right pleural effusion again seen, stable to slightly\n increased, likely loculated, with compressive atelectasis of major portions of\n the right middle and lower lobes. If the cause of the pleural effusion has not\n been established, recommended a CT of the chest with contrast, after\n thoracentesis to rule out an underlying mass. Findings: Again seen is a large pleural effusion,\n with likely a loculated component on the right, with compressive atelectasis\n of major portions of the right lower and middle lobes. There is no\n pneumothorax. The left lung is well expanded and clear. The cardiac size is\n within normal limits. The hilar and mediastinal contours are normal.",
"image_path": [
"p12/p12699874/s51280998/f46ebce4-270dbbd9-24602b65-695b054c-bcd8093c.jpg"
],
"split": "test"
},
{
"id": "a9a7d29d-d6bfc7f0-0cf3ce22-1a6a9dbc-1df52ce1",
"study_id": 53619001,
"subject_id": 15659181,
"report": "impression: Prominence of the left hilum appears slightly less confluent as compared to\n the prior study, but otherwise persists; again, underlying lymphadenopathy is\n not entirely excluded, and could be further assessed for on nonurgent chest\n CT.\n \n No focal consolidation. Findings: There is persistent prominence of the left hilum which appears site less\n confluent as compared to ___, but more prominent as compared to chest\n radiograph from ___, underlying lymphadenopathy not excluded.No\n focal consolidation is seen. There is no pleural effusion or pneumothorax. \n The cardiac and mediastinal silhouettes are stable.",
"image_path": [
"p15/p15659181/s53619001/a9a7d29d-d6bfc7f0-0cf3ce22-1a6a9dbc-1df52ce1.jpg"
],
"split": "test"
},
{
"id": "d7395617-98bb6ef8-6f0187e5-2c3df909-6f3a57c4",
"study_id": 54389393,
"subject_id": 11052273,
"report": "impression: Pulmonary vascular congestion, small effusions with probable\n fluid in the right fissure. Findings: Single portable view of the chest. Bibasilar opacities with\n blunting of the costophrenic angles which could be due to effusions. There\n are indistinct pulmonary vascular markings. Relatively lentiform-shaped\n opacity over the right mid lung is suggestive of fluid within the fissure. \n The cardiac silhouette is enlarged, similar to prior. Atherosclerotic\n calcifications are noted.",
"image_path": [
"p11/p11052273/s54389393/d7395617-98bb6ef8-6f0187e5-2c3df909-6f3a57c4.jpg"
],
"split": "test"
},
{
"id": "469c319a-57c55551-e71b3f83-73849157-a180b0ee",
"study_id": 53424979,
"subject_id": 18615099,
"report": "impression: 1. Low lung volumes. Mild interstitial pulmonary edema, improved from the\n previous exam. \n \n 2. Near-complete interval resolution of bilateral pleural effusions since\n ___. \n \n 3. Prominent mediastinal silhouette is most likely due to low lung volumes\n and patient's positioning. A repeat conventional PA and lateral radiographs\n will be helpful, when tolerated. Findings: Portable upright view of the chest demonstrates low lung volumes, which\n accentuate bronchovascular markings. There is near-complete resolution of\n bilateral pleural effusions seen on ___ exam. There is no pneumothorax\n or focal consolidation. Streaky opacity in the left juxtahilar region along\n with mild prominence of the pulmonary vascularity likely reflects mild\n interstitial edema, which is improved compared to the prior study. Heart is\n mildly enlarged. Mediastinal contour is slightly widened, which is most\n likely due to low lung volumes and patient positioning. Post-surgical changes\n related to median sternotomy and CABG are again noted.",
"image_path": [
"p18/p18615099/s53424979/469c319a-57c55551-e71b3f83-73849157-a180b0ee.jpg"
],
"split": "test"
},
{
"id": "efea65d1-1ef297f0-129ff6e4-c843bd43-2db0b71d",
"study_id": 53386512,
"subject_id": 15393401,
"report": "impression: 1. Small bilateral pleural effusions.\n 2. Mild pulmonary vascular congestion/interstitial edema.\n 3. Right upper lobe densities, for which followup chest CT could be\n considered on a non-urgent basis. Findings: There are small bilateral pleural effusions with fluid extending\n into the major and minor fissures bilaterally. There is no focal\n consolidation. Rounded densities projecting over the peripheral right upper\n lung zone on the AP view may represent pulmonary nodules. There is mild\n pulmonary vascular congestion/interstitial edema. The cardiac silhouette is\n mild-to-moderately enlarged, but stable. The mediastinal and hilar contours\n are within normal limits. Partial calcification of the aortic knob is noted.",
"image_path": [
"p15/p15393401/s53386512/efea65d1-1ef297f0-129ff6e4-c843bd43-2db0b71d.jpg"
],
"split": "test"
},
{
"id": "02e0109a-820d6579-26cf0f89-4e81bca1-65cc007f",
"study_id": 59956784,
"subject_id": 12189285,
"report": "impression: 1. Small ilateral pleural effusions with bibasilar atelectasis. No focal\n consolidations.\n 2. Fractured and misaligned median sternotomy wires are stable, indicating\n chronic sternal nonunion. Findings: Dual-lumen dialysis catheter tip is in the right atrium. The\n previously noted left internal jugular line has since been removed. Moderate\n cardiomegaly is stable. Patient is status post median sternotomy with\n fractured median sternotomy wires which appear in disarray representative of\n sternal nonunion. Again visualized are small bilateral pleural effusions,\n greater on the right than the left with bibasilar atelectasis.",
"image_path": [
"p12/p12189285/s59956784/02e0109a-820d6579-26cf0f89-4e81bca1-65cc007f.jpg"
],
"split": "test"
},
{
"id": "b2dff771-d162bb4b-180d5ef7-ed2022f8-e32ac869",
"study_id": 58369249,
"subject_id": 14794396,
"report": "impression: Ill-defined nodular opacities within the upper lobes, more pronounced on the\n left, are similar compared to the prior CT, and again may reflect a drug\n related pneumonitis. No focal consolidation identified. Minimal atelectasis in\n the left lung base. Findings: Low lung volumes are present which accentuate the size of the cardiac\n silhouette which is mildly enlarged. The mediastinal and hilar contours are\n unremarkable. Ill-defined somewhat nodular opacities are noted within the\n upper lobes bilaterally, more pronounced on the left, similar to that seen on\n the prior CT. Known smaller nodules within the lower lobes bilaterally are\n better assessed on prior CT. Minimal atelectasis is seen at the left lung\n base. No pleural effusion, focal consolidation or pneumothorax is identified.\n Multiple clips are noted within the left upper abdomen compatible with prior\n nephrectomy. No acute osseous abnormalities demonstrated.",
"image_path": [
"p14/p14794396/s58369249/b2dff771-d162bb4b-180d5ef7-ed2022f8-e32ac869.jpg"
],
"split": "test"
},
{
"id": "325742c8-9cb60d54-750e1c80-c2ee97f6-0c6d0555",
"study_id": 54907683,
"subject_id": 16015751,
"report": "impression: 1. No acute cardiopulmonary process.\n 2. 9-mm right lower lobe nodule. As per the patient's CT ___,\n the patient is due to have a followup chest CT to assess right lower lobe\n nodule, to reassess right lower lung nodule. Findings: A right lower lobe nodule is similar in appearance to prior\n radiograph and CT, however true volume cannot be measured on radiography. \n Otherwise, the lungs are clear. There is no additional nodule, consolidation,\n effusion, or pneumothorax. The heart and mediastinal contours are normal. \n There is mild tortuosity of the descending aorta. Osseous structures are\n unremarkable.",
"image_path": [
"p16/p16015751/s54907683/325742c8-9cb60d54-750e1c80-c2ee97f6-0c6d0555.jpg"
],
"split": "test"
},
{
"id": "f3627f06-7f8dc376-299731cc-3607780e-44c820e4",
"study_id": 53656059,
"subject_id": 15857729,
"report": "impression: 1. Endotracheal tube terminates 3.3 cm above the carina. \n \n 2. Unchanged mild pulmonary edema. \n \n Findings discussed with ___ by ___ via telephone on\n ___ at 11:00 AM. Findings: As compared to prior chest radiograph from earlier today, there has been\n interval placement of an endotracheal tube, terminating 3.3 cm above the\n carina. The cardiac silhouette is enlarged. As before, there is mild\n pulmonary edema. Lungs are otherwise clear. There is no focal consolidation,\n pneumothorax or pleural effusion.",
"image_path": [
"p15/p15857729/s53656059/f3627f06-7f8dc376-299731cc-3607780e-44c820e4.jpg"
],
"split": "test"
},
{
"id": "6e87c959-24dfa50c-d3d91e0a-70a0dfad-96865517",
"study_id": 57049495,
"subject_id": 14727722,
"report": "impression: 1. Mild volume overload.\n 2. No pneumoperitoneum. Findings: A hemodialysis catheter terminates at the cavoatrial\n junction. Mild cardiomegaly is unchanged. The aorta is tortuous and\n unfolded. There is increased prominence of the mediastinal silhouette, with\n distention of the azygos and central veins. No pleural effusions or\n pneumothorax. No free air under the diaphragm.",
"image_path": [
"p14/p14727722/s57049495/6e87c959-24dfa50c-d3d91e0a-70a0dfad-96865517.jpg"
],
"split": "test"
},
{
"id": "86f89f10-d6932134-162d3d5b-689149a3-81dd2b70",
"study_id": 51503417,
"subject_id": 11413236,
"report": "impression: No acute cardiopulmonary process. Findings: There are low lung volumes. The lungs are clear. There is no pleural\n effusion or pneumothorax. The cardiomediastinal silhouette is unremarkable. \n Left central line terminates in the right atrium. Median sternotomy wires and\n mediastinal clips are noted. A calcified lymph node is noted in the AP\n window.",
"image_path": [
"p11/p11413236/s51503417/86f89f10-d6932134-162d3d5b-689149a3-81dd2b70.jpg"
],
"split": "test"
},
{
"id": "6631d848-2c0cb2c2-f85d6490-f5df355f-11011cb8",
"study_id": 50184397,
"subject_id": 14081759,
"report": "impression: 1. Improving pneumonia.\n \n 2. Thin spinal syndesmophytes suggesting the possibility of an inflammatory\n arthropathy such as could be seen with ankylosing spondylitis; clinical\n correlation is suggested. Findings: The heart is at the upper limits of normal size. The mediastinal\n and hilar contours appear unchanged. Hyperinflation is noted with persistent\n reticular opacities projecting over the left lower lung but markedly improved\n since the prior radiographs. Thin flowing anterior syndesmophytes are present\n throughout the thoracic spine. This appearance has an association with\n spondyloarthropathies.",
"image_path": [
"p14/p14081759/s50184397/6631d848-2c0cb2c2-f85d6490-f5df355f-11011cb8.jpg"
],
"split": "test"
},
{
"id": "5e868309-d66225ba-ff4f44dc-5e9aa433-7712e15d",
"study_id": 55331519,
"subject_id": 13078497,
"report": "In comparison with the study of ___, there is continued\n substantial enlargement of the cardiac silhouette with diffuse bilateral\n pulmonary opacifications consistent with worsening pulmonary edema and\n bilateral pleural effusion. An endotracheal tube is now in place with its tip\n approximately 6 cm above the carina. Nasogastric tube extends at least to the\n antrum of the stomach where it crosses the lower margin of the image.",
"image_path": [
"p13/p13078497/s55331519/5e868309-d66225ba-ff4f44dc-5e9aa433-7712e15d.jpg"
],
"split": "test"
},
{
"id": "8f866521-2083f0bb-a12df756-24346ecd-5e484e40",
"study_id": 57390903,
"subject_id": 19499595,
"report": "impression: No acute cardiopulmonary process. Findings: The lungs are clear. There is no consolidation, effusion, or edema. The\n cardiomediastinal silhouette is within normal limits. Multiple fractured\n median sternotomy wires are again noted. No acute osseous abnormalities, old\n healed left anterior rib fractures are noted. Surgical clips in the right\n upper quadrant suggest prior cholecystectomy.",
"image_path": [
"p19/p19499595/s57390903/8f866521-2083f0bb-a12df756-24346ecd-5e484e40.jpg"
],
"split": "test"
},
{
"id": "cbd0493a-45581768-2a4a0cdc-ed7b4ccf-20000354",
"study_id": 50882034,
"subject_id": 13031876,
"report": "impression: Right apical rounded opacity concerning for infection or malignancy. Recommend\n repeat dedicated AP and lateral chest radiograph, or CT for further\n evaluation.\n \n These recommendations were discussed with Dr. ___ ___ the MICU at 7:30AM by\n phone. Findings: There is a rounded opacity in the right upper lobe, approximately\n 1.8cm. There is no effusion or pneumothorax. The pulmonary vasculature is\n within normal limits. There is partial visualization of anterior fusion\n hardware of the cervical spine. The heart size is magnified by portable\n technique, the mediastinal contours are unremarkable.",
"image_path": [
"p13/p13031876/s50882034/cbd0493a-45581768-2a4a0cdc-ed7b4ccf-20000354.jpg"
],
"split": "test"
},
{
"id": "2c27c769-9854b0e9-102ff0b0-b17773f0-052865d7",
"study_id": 55853389,
"subject_id": 16875792,
"report": "impression: Improved areation of the lungs in comparison to the prior study\n from ___ with a decrease in small right pleural effusion. Findings: Previously visualized right internal jugular central venous\n catheter has since been removed. Post-surgical changes are visualized with\n intact median sternotomy wires, surgical clips and coils. Calcifications are\n again noted at the aortic arch.\n \n In comparison to prior study from ___, lung aeration has\n improved bilaterally. Mild atelectatic changes are again visualized at the\n left lung base. There is a small right pleural effusion, decreased in\n comparison to the prior study.",
"image_path": [
"p16/p16875792/s55853389/2c27c769-9854b0e9-102ff0b0-b17773f0-052865d7.jpg"
],
"split": "test"
},
{
"id": "794214ee-e57ac38e-8e01e79b-648f4673-7b7f3e7c",
"study_id": 50966773,
"subject_id": 13921768,
"report": "impression: 1. There is mild vascular congestion consistent with mild fluid overload.\n \n 2. Opacification of the right upper lung could be due to asymmetric pulmonary\n edema, scapula projecting over the lung or in the appropriate clinical setting\n pneumonia.\n \n 3. Small, bilateral pleural effusions and associated bibasilar atelectasis. Findings: Single AP view of the chest provided.\n \n A right atrioventricular pacemaker appears unchanged.\n \n The right lung is hypoinflated in relation to the left lung. There is mild\n vascular congestion consistent with fluid overload.\n \n No pneumothorax. Small, bilateral pleural effusions are seen with associated\n bibasilar atelectasis.\n \n Hilar contours are normal. The aorta is tortuous.\n \n Severe S-shaped is unchanged.",
"image_path": [
"p13/p13921768/s50966773/794214ee-e57ac38e-8e01e79b-648f4673-7b7f3e7c.jpg"
],
"split": "test"
},
{
"id": "dfa28d80-2c323234-0b53a9cc-fa22a300-37d9a55c",
"study_id": 59828891,
"subject_id": 13896515,
"report": "impression: Moderate left pleural effusion with overlying atelectasis, underlying\n consolidation not excluded. Similar pulmonary edema. Findings: Patient is status post median sternotomy. Left-sided pacer device is grossly\n stable in position. There is a moderate left pleural effusion with overlying\n atelectasis, left base consolidation is not excluded. Similar pulmonary edema\n persists, possibly asymmetric on the left. No right pleural effusion is seen.\n There is no pneumothorax. Cardiac and mediastinal silhouettes are stable.",
"image_path": [
"p13/p13896515/s59828891/dfa28d80-2c323234-0b53a9cc-fa22a300-37d9a55c.jpg"
],
"split": "test"
},
{
"id": "b046c8c0-a7b3367e-546b4f8c-222c475c-98dbe5b7",
"study_id": 50717913,
"subject_id": 14236258,
"report": "impression: No pulmonary edema or pneumonia. Findings: Left-sided dual lumen subclavian central venous catheter tip terminates within\n the proximal right atrium, coursing through a vascular stent within the left\n brachiocephalic vein and superior vena cava. Cardiac silhouette size is\n normal. Mild rightward deviation of the trachea with left superior\n mediastinal mass compatible with a known thyroid goiter is unchanged. Hilar\n contours are unchanged. Pulmonary vasculature is not engorged. Subsegmental\n atelectasis is noted in the lung bases without focal consolidation. No\n pleural effusion or pneumothorax is demonstrated. Marked degenerative changes\n of the left glenohumeral joints and remote right posterior rib are re-\n demonstrated.",
"image_path": [
"p14/p14236258/s50717913/b046c8c0-a7b3367e-546b4f8c-222c475c-98dbe5b7.jpg"
],
"split": "test"
},
{
"id": "0f5eff83-85fc727f-a7691318-ee53b149-e9d6062b",
"study_id": 59787158,
"subject_id": 13475033,
"report": "impression: Again seen reticular interstitial opacities distributed evenly\n across both lungs, stable over multiple prior radiographs, previously\n attributed to chronic hypersensitivity pneumonitis. Mild superimposed fluid\n overload cannot be excluded No focal consolidation. Findings: A right-sided hemodialysis catheter\n terminates at the right atrium. Again seen are reticular interstitial\n opacities distributed evenly across both lungs, stable over multiple prior\n radiographs, previously attributed to chronic hypersensitivity pneumonitis on\n the chest CT from ___. The cardiac and mediastinal silhouettes\n are unchanged. The central pulmonary vessels appear more prominent since the\n ___ study. Superimposed mild edema cannot be excluded. There is no\n focal consolidation, pleural effusion, or pneumothorax.",
"image_path": [
"p13/p13475033/s59787158/0f5eff83-85fc727f-a7691318-ee53b149-e9d6062b.jpg"
],
"split": "test"
},
{
"id": "f04feadc-4a8ef216-30473af0-2ae9053c-63131816",
"study_id": 58611846,
"subject_id": 13067703,
"report": "impression: Mild pulmonary vascular congestion without evidence of overt\n pulmonary edema. At least partially loculated left-sided pleural effusion\n with possible adjacent atelectasis. Free air below the diaphragm compatible\n with peritoneal dialysis. Right suprahilar mass as above. Findings: PA and lateral views of the chest are compared to previous exam\n from ___. Dual-lead pacing device is again seen with lead tips in\n stable position. Right upper lobe/suprahilar opacity with fiducial marker is\n again seen, not significantly changed from exam from two weeks prior. Left\n side pleural effusion which is seen with loculation posteriorly. There is\n mild pulmonary vascular congestion without frank pulmonary edema. Free air\n seen below the right hemidiaphragm is compatible with daily peritoneal\n dialysis. Osseous and soft tissue structures are unremarkable.",
"image_path": [
"p13/p13067703/s58611846/f04feadc-4a8ef216-30473af0-2ae9053c-63131816.jpg"
],
"split": "test"
},
{
"id": "eb810218-60a5a044-852328e8-4cdeeaef-1befd540",
"study_id": 56094236,
"subject_id": 18224196,
"report": "impression: 1. Increased small bilateral pleural effusions.\n 2. Cardiomegaly.\n 3. Hyperinflated lungs corresponding with known emphysema.\n \n These findings were discussed with Dr. ___ by Dr. ___ by\n telephone at 10:32 a.m. on ___. Findings: Small bilateral pleural effusions are increased in size compared to\n most recent prior exam. There is no focal consolidation. The lungs are\n hyperinflated with emphysematous changes as seen on prior CT. Heart size is\n increased, similar compared to prior.",
"image_path": [
"p18/p18224196/s56094236/eb810218-60a5a044-852328e8-4cdeeaef-1befd540.jpg"
],
"split": "test"
},
{
"id": "463d2a28-b411bb98-f7bda38e-7030ebb9-74a8a1e0",
"study_id": 58701930,
"subject_id": 16662264,
"report": "impression: No evidence of lobar pneumonia. Opacity adjacent to the cardiac apex at the\n left base appears to be chronic, though if there is concern for developing\n pneumonia radiographic follow-up would be appropriate. Findings: Subtle increased density adjacent to the cardiac apex, with obscuration of the\n lower left cardiac border, has been present on multiple prior studies, and is\n thus likely chronic. No corresponding abnormality was identified on the\n lateral view performed one day prior. There is no further parenchymal opacity\n identified. There is no pleural effusion or pneumothorax. The\n cardiomediastinal contours are unchanged. There is no pulmonary vascular\n congestion or edema. There are no acute osseous abnormalities.",
"image_path": [
"p16/p16662264/s58701930/463d2a28-b411bb98-f7bda38e-7030ebb9-74a8a1e0.jpg"
],
"split": "test"
},
{
"id": "5e2d7a5c-0cca16ec-3dff48d4-bab26e70-6bea7f6d",
"study_id": 54479348,
"subject_id": 15809646,
"report": "impression: 1. Tube and lines are in adequate position.\n 2. The remaining of the exam is unchanged without significant acute\n cardiopulmonary findings. Findings: New ET tube ends 2.9 cm above the carina. Right jugular line is in lower SVC.\n Left upper lobe rounded atelectasis was better assessed in recent CT, and\n there is minimal chronic thickening of the pleura at the costodiaphragmatic\n angles.",
"image_path": [
"p15/p15809646/s54479348/5e2d7a5c-0cca16ec-3dff48d4-bab26e70-6bea7f6d.jpg"
],
"split": "test"
},
{
"id": "426bad34-c84321a7-37a7e076-e0395dc2-f2a3123a",
"study_id": 59800551,
"subject_id": 15131736,
"report": "impression: Cardiomegaly and enlarged pulmonary arteries without definite\n acute cardiopulmonary process. Findings: Frontal and lateral views of the chest. The lungs are clear of\n confluent consolidation, effusion, or overt pulmonary edema. Cardiomegaly is\n stable. Enlarged pulmonary arteries are also seen, unchanged. \n Atherosclerotic calcifications seen at the aortic arch.",
"image_path": [
"p15/p15131736/s59800551/426bad34-c84321a7-37a7e076-e0395dc2-f2a3123a.jpg"
],
"split": "test"
},
{
"id": "47b82a26-321d12c0-2e8e3d70-fea4fb45-3e201e4c",
"study_id": 56465441,
"subject_id": 16055653,
"report": "In comparison with the study of ___, there has been placement of a\n right IJ catheter that extends to the lower portion of the SVC. No evidence\n of pneumothorax or widening of the mediastinum.\n \n In comparison with the prior study, there are even lower lung volumes, but\n otherwise little change in the appearance of the heart and lungs.",
"image_path": [
"p16/p16055653/s56465441/47b82a26-321d12c0-2e8e3d70-fea4fb45-3e201e4c.jpg"
],
"split": "test"
},
{
"id": "460564da-f530de8e-fabb35c1-53d562ae-404235d0",
"study_id": 56761306,
"subject_id": 19016834,
"report": "impression: 1. No pneumothorax or pneumomediastinum.\n 2. Increasing peribronchial opacification at the right base likely represents\n aspiration, possibly pneumonia. Findings: There is no pneumothorax or pneumomediastinum. The\n cardiomediastinal silhouette is normal. A small right pleural effusion is\n unchanged. Since the prior radiograph, there has been increased nodular\n peribronchial opacification, most readily explained by chronic aspiration. \n Mild hazy opacification at the left base is unchanged and likely represents\n chronic atelectasis.",
"image_path": [
"p19/p19016834/s56761306/460564da-f530de8e-fabb35c1-53d562ae-404235d0.jpg"
],
"split": "test"
},
{
"id": "58d7d80b-3610f757-0e540435-44dbf9dd-12c5b583",
"study_id": 55169735,
"subject_id": 18224196,
"report": "following repositioning, the coiled Dobbhoff tube in the mid\n esophagus has resolved. The distal end is within the stomach. Right internal\n jugular sheath is at upper SVC. Patient is following median sternotomy for\n mitral valve replacement and sternal sutures are intact. Mild-to-moderate\n right pleural effusion associated with adjacent lung atelectasis is unchanged\n since prior radiograph from ___. No other interval changes in the\n lung.",
"image_path": [
"p18/p18224196/s55169735/58d7d80b-3610f757-0e540435-44dbf9dd-12c5b583.jpg"
],
"split": "test"
},
{
"id": "8f79faef-d6ab7ef3-75eb04f9-26fe138d-a9352552",
"study_id": 57765976,
"subject_id": 16848073,
"report": "In comparison with the study of ___, there is little overall\n change. Cardiac silhouette is within normal limits and there is no evidence\n of acute pneumonia or vascular congestion. Mild atelectatic changes are\n suggested at the bases. \n \n Specifically, no evidence of pneumothorax or pneumomediastinum following the\n procedure.",
"image_path": [
"p16/p16848073/s57765976/8f79faef-d6ab7ef3-75eb04f9-26fe138d-a9352552.jpg"
],
"split": "test"
},
{
"id": "638f2c7f-1ddfe2c3-062f8057-b3e8a5aa-17b03955",
"study_id": 58307391,
"subject_id": 10274145,
"report": "impression: No acute intrathoracic process. Findings: The lungs are well expanded and clear. The\n cardiomediastinal silhouette, hilar contours, and pleural surfaces are normal.\n No pleural effusion or pneumothorax is present. Sternal wires are intact.",
"image_path": [
"p10/p10274145/s58307391/638f2c7f-1ddfe2c3-062f8057-b3e8a5aa-17b03955.jpg"
],
"split": "test"
},
{
"id": "66a29579-968d1700-4071c06f-fde97b0f-8ca7ce9b",
"study_id": 53825501,
"subject_id": 11569093,
"report": "Right-sided chest tube has been removed. There is a\n hydropneumothorax in the inferior right chest. The amount of fluid has\n increased compared to the study from two days prior. The thick irregular\n pleural disease around the right lung is again visualized. The left lung is\n clear. Cardiac and mediastinal silhouettes are unchanged.",
"image_path": [
"p11/p11569093/s53825501/66a29579-968d1700-4071c06f-fde97b0f-8ca7ce9b.jpg"
],
"split": "test"
},
{
"id": "7f656d45-d1f74ac4-4ad4b221-3f4ff982-a2435c40",
"study_id": 57798090,
"subject_id": 16957952,
"report": "impression: 1. Mild left basal atelectasis; no pneumonia.\n \n 2. Chronic mild to moderate cardiomegaly and pulmonary venous hypertension,\n but no pulmonary edema.\n \n 3. Chronically enlarged atherosclerotic thoracic aorta, with no focal\n aneurysm. Findings: Heterogeneous left basilar opacities do not have a correlate on the\n lateral radiograph and are likely minimal atelectasis. The lungs are\n otherwise clear. Mild pulmonary vascular congestion is not accompanied\n interstitial edema or pleural abnormality. Mild to moderate cardiomegaly is\n chronic. The thoracic aorta is generally enlarged, very tortuous and\n moderately calcified but neither focally aneurysmal nor changed since at least\n ___. The patient has had midline sternotomy and CABG. A right cervical\n rib is seen. Multilevel degenerative changes of the thoracic spine include\n unchanged wedging of a lower thoracic vertebral body.",
"image_path": [
"p16/p16957952/s57798090/7f656d45-d1f74ac4-4ad4b221-3f4ff982-a2435c40.jpg"
],
"split": "test"
},
{
"id": "98a6b1be-37d7c0d7-9de7d63b-c95bf9a0-17713dcd",
"study_id": 57345846,
"subject_id": 13979643,
"report": "As compared to the previous radiograph, the nasogastric tube has\n been advanced. The tip of the tube, however, is directed towards the\n gastroesophageal junction. No evidence of complications, no other relevant\n changes.",
"image_path": [
"p13/p13979643/s57345846/98a6b1be-37d7c0d7-9de7d63b-c95bf9a0-17713dcd.jpg"
],
"split": "test"
},
{
"id": "dae1f21b-39bf30ae-e438eeeb-ff8bfb80-1d3f7d87",
"study_id": 52019812,
"subject_id": 15032623,
"report": "impression: No acute cardiopulmonary process. Findings: AP and lateral chest radiographs are provided. There is no focal\n consolidation, pleural effusion, or pneumothorax. The cardiomediastinal\n silhouette is unremarkable. Median sternotomy wires are intact. Surgical\n clips are seen along the left heart border. There are degenerative changes\n throughout the thoracic spine and at the right acromioclavicular joint.",
"image_path": [
"p15/p15032623/s52019812/dae1f21b-39bf30ae-e438eeeb-ff8bfb80-1d3f7d87.jpg"
],
"split": "test"
},
{
"id": "637914b1-994c0db2-29d6aba2-56b11076-9cfcc278",
"study_id": 56991236,
"subject_id": 13291370,
"report": "impression: New right upper lobe pneumonia. Mild pulmonary vascular congestion. Findings: The patient is status post median sternotomy and CABG. Left-sided pacemaker\n device is noted with single lead terminating in the right ventricle,\n unchanged. The aortic knob is calcified and aorta remains mildly tortuous. \n There is new mild pulmonary vascular congestion. Hyperinflation of the lungs\n is re- demonstrated. New consolidative opacity within the right upper lobe is\n concerning for pneumonia. And ill-defined nodular opacity within the right\n upper lung field measuring up to 10 mm is also new, and likely infectious in\n etiology. No large pleural effusion or pneumothorax is present. No acute\n osseous abnormality is seen. There are multilevel degenerative changes in the\n thoracic spine.",
"image_path": [
"p13/p13291370/s56991236/637914b1-994c0db2-29d6aba2-56b11076-9cfcc278.jpg"
],
"split": "test"
},
{
"id": "5932603f-64abd8a2-713ef8b9-907f95b0-106004c5",
"study_id": 53035658,
"subject_id": 19720782,
"report": "impression: Unchanged appearance of the chest with findings of right pleural\n effusion, loculated and lower lobe atelectasis as well as right perihilar\n fibrosis is unchanged. Please refer to subsequent CTA chest for further\n details. Findings: AP portable upright chest radiograph was provided. Loculated right\n pleural effusion is again seen, with compressive lower lobe atelectasis\n unchanged. There is right perihilar opacity which likely reflects known\n fibrosis as seen on prior CT. New consolidation is seen. No pneumothorax. \n Overall, cardiomediastinal silhouette is stable. Bony structures are intact.",
"image_path": [
"p19/p19720782/s53035658/5932603f-64abd8a2-713ef8b9-907f95b0-106004c5.jpg"
],
"split": "test"
},
{
"id": "561aa77f-36bdb76f-e2a79068-a9c24ac5-0e745c62",
"study_id": 57622301,
"subject_id": 16826047,
"report": "impression: Persistent consolidation and loculated right pleural effusion\n with PleurX catheter in unchanged position. Findings: PA and lateral views of the chest are provided. PleurX catheter is\n again seen on the right with its tip at the level of the right sixth and\n seventh posterior rib interspace. There is persistent effusion and\n consolidation within the right lung, though there is slight improvement in the\n aeration in the right upper lung as compared with the prior chest radiograph. \n There is persistent loculated right pleural effusion for which a slight\n increased fluid component is seen along the right lateral upper lung. The\n left lung is unchanged and clear. Heart size cannot be assessed due to\n effacement of the right heart border. Bony structures appear intact.",
"image_path": [
"p16/p16826047/s57622301/561aa77f-36bdb76f-e2a79068-a9c24ac5-0e745c62.jpg"
],
"split": "test"
},
{
"id": "33222196-20a22f7b-b04dd8d7-3c2d9960-8b9630bb",
"study_id": 56513752,
"subject_id": 16662264,
"report": "In comparison with the study of ___, there is progressive decrease\n in the opacification at the bases, consistent with the clinical diagnosis of\n resolving pneumonia. However, there is still some opacification especially at\n the left base and overlying the cardiac silhouette. This is consistent with a\n lingular consolidation.",
"image_path": [
"p16/p16662264/s56513752/33222196-20a22f7b-b04dd8d7-3c2d9960-8b9630bb.jpg"
],
"split": "test"
},
{
"id": "6b77cbf9-987963b7-937492b5-149802aa-75535076",
"study_id": 52891865,
"subject_id": 16672854,
"report": "impression: Central pulmonary vascular congestion with moderate interstitial\n edema, concerning for cardiac decompensation. Findings: The patient is status post median\n sternotomy and prosthetic valve placement. The heart is mildly enlarged. The\n central pulmonary vessels are engorged and congested. Patchy bibasilar\n opacities are present, and there are multiple Kerley B lines, representing\n moderate interstitial edema. A tiny left pleural effusion is present. There\n is no pneumothorax.",
"image_path": [
"p16/p16672854/s52891865/6b77cbf9-987963b7-937492b5-149802aa-75535076.jpg"
],
"split": "test"
},
{
"id": "bced25e3-835951a9-cb1436cd-d095e342-730a3489",
"study_id": 53780576,
"subject_id": 13352405,
"report": "impression: Multiple chronic appearing left-sided rib fractures. No pneumothorax.\n Blunting of the costophrenic angle on the right likely represents pleural\n scarring and a small effusion, not significantly changed from ___. Findings: Chronic left-sided rib fractures are again noted. The cardiomediastinal and\n hilar contours are unchanged from ___. Pleural thickening and blunting at the\n right costophrenic angle is again demonstrated, and is stable from the prior\n exam in ___ and likely represents pleural scarring and a small pleural\n effusion. No focal consolidation or pneumothorax is identified.",
"image_path": [
"p13/p13352405/s53780576/bced25e3-835951a9-cb1436cd-d095e342-730a3489.jpg"
],
"split": "test"
},
{
"id": "ac9b202d-33441ce8-29b49c66-d903a94d-74c87396",
"study_id": 55596851,
"subject_id": 19765968,
"report": "In comparison with study of ___, there is little change. There\n may be some minimal residual elevation of pulmonary venous pressure and small\n pleural effusion with bibasilar atelectasis. Central catheter remains in\n place.",
"image_path": [
"p19/p19765968/s55596851/ac9b202d-33441ce8-29b49c66-d903a94d-74c87396.jpg"
],
"split": "test"
},
{
"id": "a02fc8d7-4d89d7b2-2bcaaf26-ebd72059-2e9d5341",
"study_id": 54225810,
"subject_id": 17189198,
"report": "impression: Bilateral ground glass opacities and small bilateral pleural\n effusions are consistent with moderate pulmonary edema. In the proper\n clinical setting, a pneumonia cannot be excluded. Can consider a repeat chest\n radiograph after diuresis. Findings: There is hilar congestion and diffuse bilateral ground glass\n opacities, most predominant at the bases, slightly improved from prior exam,\n and most consistent with pulmonary edema. An underlying pneumonia cannot be\n fully excluded. There are trace bilateral pleural effusions. There is no\n pneumothorax. The cardiac silhouette is moderately enlarged and unchanged\n from the prior exam. The mediastinal contours are normal.",
"image_path": [
"p17/p17189198/s54225810/a02fc8d7-4d89d7b2-2bcaaf26-ebd72059-2e9d5341.jpg"
],
"split": "test"
},
{
"id": "553f6199-37bc0e92-8f246bbd-f36f847e-8d0c8e14",
"study_id": 59685259,
"subject_id": 19499595,
"report": "impression: No evidence of pleural effusion or focal consolidation. Findings: The heart size, mediastinal, and hilar contours are normal. The lungs are\n clear and well expanded without effusion or focal consolidation. No acute rib\n fractures are seen. Several fractured sternotomy wires are unchanged.",
"image_path": [
"p19/p19499595/s59685259/553f6199-37bc0e92-8f246bbd-f36f847e-8d0c8e14.jpg"
],
"split": "test"
},
{
"id": "669b4965-be67a9dd-0ba00b96-3ed4d288-597c3f17",
"study_id": 54247614,
"subject_id": 13881772,
"report": "impression: Continued evidence of mild pulmonary vascular congestion and small pleural\n effusions. There is a suggestion of increased density in the retrocardiac\n area. This region could be better assessed by a lateral view if clinically\n indicated. A double-lumen right internal jugular catheter is in central\n position. Findings: 1 AP view. There is evidence for increased density in the retrocardiac area in\n the left hemidiaphragm is indistinct. The lung bases are partially obscured by\n extensive costochondral calcification. The costophrenic sulci are blunted. \n Bronchovascular markings are mildly increased, as before. The heart and\n mediastinal structures are unchanged as well. A double-lumen right internal\n jugular catheter has been inserted and terminates in the region of the lower\n superior vena cava.",
"image_path": [
"p13/p13881772/s54247614/669b4965-be67a9dd-0ba00b96-3ed4d288-597c3f17.jpg"
],
"split": "test"
},
{
"id": "715d0cdc-ddee4d9b-b5a28b77-350e1063-bc606f0d",
"study_id": 54602632,
"subject_id": 19991135,
"report": "In comparison with the study of ___, the monitoring and support\n devices remain in place without definite pneumothorax. The left lung remains\n essentially clear except for some atelectatic changes at the base. Extensive\n subcutaneous emphysema again persists along the right lateral chest wall. \n Opacification along the mediastinal border on the right again could reflect\n collection of pleural fluid. The development of hematoma cannot be excluded\n in the appropriate clinical setting.",
"image_path": [
"p19/p19991135/s54602632/715d0cdc-ddee4d9b-b5a28b77-350e1063-bc606f0d.jpg"
],
"split": "test"
},
{
"id": "7d6acf38-2ce33bef-4722c2e9-c0f089ec-c06a5100",
"study_id": 59343122,
"subject_id": 18767957,
"report": "impression: Findings suggestive of interstitial edema. No superimposed acute\n consolidation or effusion. Unchanged cardiomegaly. Findings: PA and lateral views of the chest. The lungs are clear of focal consolidation\n or pleural effusion. There are however increased interstitial markings\n throughout the lungs and enlarged cardiac silhouette which is unchanged from\n prior. There is no acute osseous abnormality detected.",
"image_path": [
"p18/p18767957/s59343122/7d6acf38-2ce33bef-4722c2e9-c0f089ec-c06a5100.jpg"
],
"split": "test"
},
{
"id": "7482f461-69260c1c-6d80e1ef-de9d3167-e122de4e",
"study_id": 51887095,
"subject_id": 11569093,
"report": "impression: Stable chest radiograph. Findings: There is persistent opacification of the right lower lung field,\n likely due to known pleural effusion and atelectasis. Small left pleural\n effusion is again noted. Overall, there has been no significant interval\n change. Endotracheal tube, left internal jugular catheter, and esophageal\n catheter are again seen in similar positions with esophageal catheter tip out\n of view. No pneumothorax is detected.",
"image_path": [
"p11/p11569093/s51887095/7482f461-69260c1c-6d80e1ef-de9d3167-e122de4e.jpg"
],
"split": "test"
},
{
"id": "2001d733-0290af9c-11d2f658-a475b597-45f1095a",
"study_id": 51227270,
"subject_id": 14387068,
"report": "Comparison is made to prior study from ___.\n \n There is a very large hydropneumothorax on the right side. There is\n compression of the lung parenchyma. There is also some mediastinal shift to\n the left side. The left lung appears well aerated without focal\n consolidation, pleural effusions or pneumothoraces. The right base has\n increased in the size with pleural effusion, however, this may be secondary to\n patient positioning. There is a pleural-based catheter at the right base.",
"image_path": [
"p14/p14387068/s51227270/2001d733-0290af9c-11d2f658-a475b597-45f1095a.jpg"
],
"split": "test"
},
{
"id": "0973f2e4-fd436409-ac1ae199-94dae0f7-7ed0d26a",
"study_id": 53158366,
"subject_id": 13450581,
"report": "impression: Left upper lobe linear opacities at site of prior treatment for lung\n carcinoma. Findings: The previously described left upper lobe mass is not seen on this radiograph. \n Linear opacities in the left upper lobe can be and a sequelae of prior\n treatment lung carcinoma. No pulmonary edema, pleural effusion or\n pneumothorax. The cardiomediastinal contours are unchanged.",
"image_path": [
"p13/p13450581/s53158366/0973f2e4-fd436409-ac1ae199-94dae0f7-7ed0d26a.jpg"
],
"split": "test"
},
{
"id": "210f9c01-9e0728bf-4b8ec9bf-34d1564e-16cf509c",
"study_id": 56093476,
"subject_id": 15881535,
"report": "impression: Interval enlargement of the cardiac silhouette even accounting\n for patient and technical factors. This likely signifies at least an increase\n in the size of the apparently known pericardial effusion. Findings: Lung volumes are diminished which exaggerates the cardiomediastinal\n configuration. However, even accounting for this change, there has been a\n relative dramatic increase in the size of the cardiac silhouette with now\n somewhat globular morphology. Ill-defined opacity is noted in the\n retrocardiac left lower lobe which is likely atelectasis given the volume\n loss. There is no focal consolidation. No definite effusion or pneumothorax\n is seen. The osseous structures are unremarkable. Incidental note is made of\n internal fixation hardware, incompletely evaluated, involving the mid\n diaphysis of the right clavicle. Tubing loops over the epigastric region and\n with the tip projecting at the dome of the left hemidiaphragm over the cardiac\n silhouette.",
"image_path": [
"p15/p15881535/s56093476/210f9c01-9e0728bf-4b8ec9bf-34d1564e-16cf509c.jpg"
],
"split": "test"
},
{
"id": "4c813a56-c3955f56-d8575305-9347eb08-6c581dc1",
"study_id": 53418217,
"subject_id": 17763117,
"report": "impression: Pulmonary vascular engorgement without overt pulmonary edema. No\n pneumonia. Findings: Frontal AP and lateral views of the chest were obtained. The\n patient is rotated. The left pectoral ICD leads end in the expected locations\n of the right atrium and right ventricle. The patient is status post median\n sternotomy with intact wires. A right PICC ends in the upper SVC. There is no\n focal consolidation, pleural effusion or pneumothorax. Opacity at the right\n cardiophrenic angle corresponds to mediastinal fat on CT ___. Aortic\n knob calcifications are noted. There is pulmonary vascular engorgement and\n mild cardiomegaly. \n \n A nodule in the right upper lung is not well visualized on this study and is\n better evaluated on chest CT ___. Multiple calcified granulomas are\n noted.",
"image_path": [
"p17/p17763117/s53418217/4c813a56-c3955f56-d8575305-9347eb08-6c581dc1.jpg"
],
"split": "test"
},
{
"id": "1b7bd4fd-2ddbc2c0-70d7a8f2-ff32883c-5c2ce9af",
"study_id": 55316579,
"subject_id": 13475033,
"report": "impression: New mild interstitial edema and tiny right pleural effusion. Findings: Interstitial prominence has increased compared to prior, suggestive of mild\n edema. No focal consolidation or pneumothorax is detected. Tiny right\n pleural effusion appears new compared to prior. Heart and mediastinal\n contours appear stable with mild cardiomegaly.",
"image_path": [
"p13/p13475033/s55316579/1b7bd4fd-2ddbc2c0-70d7a8f2-ff32883c-5c2ce9af.jpg"
],
"split": "test"
},
{
"id": "d2738a71-3831deab-ac7d0164-16ff75a4-284704ff",
"study_id": 52943383,
"subject_id": 10523725,
"report": "impression: No significant change since the prior study and no evidence of\n overt pulmonary edema. Findings: Since the prior radiograph there has been no significant change. \n There is no focal consolidation, pleural effusion, pneumothorax or pulmonary\n edema. Cardiomediastinal silhouette is unchanged and notable for tortuous\n aorta and mild cardiomegaly. Median sternotomy wires are present and intact. \n Clips are seen in the midline of the thorax. Bony structures are intact.",
"image_path": [
"p10/p10523725/s52943383/d2738a71-3831deab-ac7d0164-16ff75a4-284704ff.jpg"
],
"split": "test"
},
{
"id": "5c2bf1b4-d3738135-b0f5cea4-bfa67dda-166feb65",
"study_id": 58857549,
"subject_id": 15612622,
"report": "impression: No acute cardiopulmonary abnormality. Findings: Heart size is borderline enlarged with a left ventricular predominance. The\n aorta is unfolded. Mediastinal and hilar contours are unchanged. Calcified\n nodule in the left mid lung field is similar, compatible with a granuloma. \n Lungs are clear without focal consolidation. Pulmonary vasculature is normal.\n No pleural effusion or pneumothorax is seen. There are multilevel moderate\n degenerative changes in the thoracic spine.",
"image_path": [
"p15/p15612622/s58857549/5c2bf1b4-d3738135-b0f5cea4-bfa67dda-166feb65.jpg"
],
"split": "test"
},
{
"id": "177495f2-996738c6-f03f52bd-f9e6aad1-913f1885",
"study_id": 56012267,
"subject_id": 19016834,
"report": "impression: Improved right perihilar consolidation likely representing infection. Findings: The cardiac, mediastinal and hilar contours appear unremarkable. The large\n right perihilar consolidation, likely representing infection, has improved\n since the most recent prior examination of ___. Minimal\n air-fluid level is noted within the neoesophagus on the lateral view.",
"image_path": [
"p19/p19016834/s56012267/177495f2-996738c6-f03f52bd-f9e6aad1-913f1885.jpg"
],
"split": "test"
},
{
"id": "e8f40dc1-eb1d35c9-581a0b09-a78294c8-1a9ab9f1",
"study_id": 50640370,
"subject_id": 18417750,
"report": "impression: Findings suggesting mild pulmonary vascular congestion. Findings: A dual lead pacemaker/ICD device with two leads appears unchanged. \n The patient is status post endovascular aortic valve replacement. Mitral\n annular calcifications are present. The heart is moderately enlarged. The\n mediastinal and hilar contours appear unchanged. A mild new interstitial\n abnormality suggests vascular congestion, but no focal opacities are\n identified. There is no pleural effusion or pneumothorax. \n \n The patient is again status post vertebroplasty of the T10 vertebral body\n which demonstrates a fragmented moderate compression deformity with slight\n retropulsion of the dominant posterior fragment, but not significantly\n changed. Prior posterior fusion involving T10 and T11 also appears unchanged.\n A moderate biconcave L1 compression deformity appears unchanged.",
"image_path": [
"p18/p18417750/s50640370/e8f40dc1-eb1d35c9-581a0b09-a78294c8-1a9ab9f1.jpg"
],
"split": "test"
},
{
"id": "fd446187-4918e937-9c58f354-86463aca-af75d8a6",
"study_id": 56592251,
"subject_id": 14295224,
"report": "impression: Near resolution of right lower lobe pneumonia. Additional followup chest\n x-ray in 4 weeks may be helpful to document complete resolution or stability\n of residual right infrahilar opacity. Findings: Previously reported right lower lobe pneumonia has nearly resolved with only\n mild residual peribronchiolar opacification remaining in the right infrahilar\n area. A small right pleural effusion has nearly resolved. Localized\n bronchiectasis and scarring in the right upper lobe is similar to older\n studies. A small nodule at the right lung base is similar to previous CT of ___. Postoperative changes in the chest are similar including post\n radiation alterations and findings related to previous esophagectomy and\n pull-up procedure.",
"image_path": [
"p14/p14295224/s56592251/fd446187-4918e937-9c58f354-86463aca-af75d8a6.jpg"
],
"split": "test"
},
{
"id": "b68832f5-cb74ec26-125ffe9e-4e092765-e97f8be0",
"study_id": 50093776,
"subject_id": 15612622,
"report": "impression: Stable mediastinal contour which is not widened. Findings: Frontal and lateral views of the chest were obtained. Lungs are\n hyperinflated, flattening of the diaphragms, suggesting chronic obstructive\n pulmonary disease. 7-mm calcific focus in the left mid chest is stable. \n Cardiac silhouette top normal to mildly enlarged. The aorta is tortuous. \n Minimal lingular atelectasis is seen. There is also mild biapical pleural\n thickening. No focal consolidation is seen. There is no pleural effusion or\n pneumothorax. The mediastinal contours are stable and do not appear widened. \n There is diffuse osteopenia.",
"image_path": [
"p15/p15612622/s50093776/b68832f5-cb74ec26-125ffe9e-4e092765-e97f8be0.jpg"
],
"split": "test"
},
{
"id": "1344069d-f5bbd6ab-956a09d4-76f8bac1-7d8c3a04",
"study_id": 59203230,
"subject_id": 18835687,
"report": "impression: No acute intrathoracic process. No overt evidence of PCP. Findings: Chest frontal and lateral radiographs demonstrate unremarkable\n cardiomediastinal and hilar contours. Lungs are clear. No pleural effusion\n or pneumothorax evident. Minimal degenerative change at right\n acromioclavicular joint. No osseous abnormality is identified.",
"image_path": [
"p18/p18835687/s59203230/1344069d-f5bbd6ab-956a09d4-76f8bac1-7d8c3a04.jpg"
],
"split": "test"
},
{
"id": "97e98c24-079ba543-3cfe0fbe-b97b30b8-bbd0e9a5",
"study_id": 59891992,
"subject_id": 15438386,
"report": "Again, there are low lung volumes. Mild blunting of the costophrenic angles\n may in part relate to low lung volumes with likely trace pleural effusions. \n Additional subtle bibasilar opacities likely represent atelectasis. The\n patient is rotated to the right. The cardiac and mediastinal silhouettes are\n similar with the cardiac silhouette possibly slightly less prominent as\n compared to the prior study. No evidence of pneumothorax is seen. Chronic\n deformity of the right clavicle is again noted.",
"image_path": [
"p15/p15438386/s59891992/97e98c24-079ba543-3cfe0fbe-b97b30b8-bbd0e9a5.jpg"
],
"split": "test"
},
{
"id": "8b08f860-baa48664-53adfb7a-98469602-de45d5e7",
"study_id": 59372049,
"subject_id": 19748558,
"report": "impression: No acute cardiopulmonary process. Findings: PA and lateral chest radiographs are provided. There is no focal\n consolidation, pneumothorax or pleural effusion. The lungs are hyperinflated.\n Cardiomediastinal silhouette is unremarkable. There is no free air under the\n right hemidiaphragm. There are no concerning osseous lesions.",
"image_path": [
"p19/p19748558/s59372049/8b08f860-baa48664-53adfb7a-98469602-de45d5e7.jpg"
],
"split": "test"
},
{
"id": "bbfadd26-26a1370d-69d5f8f9-5b210fd9-a89a0589",
"study_id": 51877138,
"subject_id": 15259244,
"report": "impression: Patchy left basilar opacity, highly suggestive of atelectasis in\n association with a small-to-moderate suspected pleural effusion, although\n opacification is not entirely specific as the etiology. Findings: The patient is status post mitral valve replacement and probably\n coronary artery bypass graft surgery. The heart is mildly enlarged. There is\n patchy basilar opacification suggesting a combination of atelectasis and\n pleural effusion. Streaky left upper lobe opacity suggests minor atelectasis\n or scarring which is unchanged. There is no pneumothorax. No free air is\n demonstrated.",
"image_path": [
"p15/p15259244/s51877138/bbfadd26-26a1370d-69d5f8f9-5b210fd9-a89a0589.jpg"
],
"split": "test"
},
{
"id": "c9cd6c49-2bebaea2-82c0c5dc-c3d2e9a7-560599b0",
"study_id": 51002383,
"subject_id": 10933609,
"report": "impression: Bilateral upper lobe scarring unchanged without evidence of superimposed acute\n process. Findings: PA and lateral views of the chest. Bilateral upper lobe scarring is seen with\n superior retraction of the hila. The lung volumes are relatively low. There\n is no evidence of superimposed acute process. Cardiomediastinal silhouette is\n stable. Surgical clips in the upper abdomen again noted. Osseous structures\n are essentially unremarkable noting probable right glenoid orthopedic\n hardware.",
"image_path": [
"p10/p10933609/s51002383/c9cd6c49-2bebaea2-82c0c5dc-c3d2e9a7-560599b0.jpg"
],
"split": "test"
},
{
"id": "d45a4f1c-aa9b0b1d-714e476e-b6f28f01-34d6bcdc",
"study_id": 55799349,
"subject_id": 13484161,
"report": "impression: Enlarged cardiac silhouette and moderate interstitial edema. Findings: Frontal and lateral views of the chest were obtained. There is\n prominence of the interstitial markings suggesting moderate interstitial\n edema. No large pleural effusion is seen. There is no evidence of\n pneumothorax. The cardiac silhouette is enlarged. The aorta is tortuous.",
"image_path": [
"p13/p13484161/s55799349/d45a4f1c-aa9b0b1d-714e476e-b6f28f01-34d6bcdc.jpg"
],
"split": "test"
},
{
"id": "b85f7da5-828bea81-c7e95d37-4650d910-3c367fa4",
"study_id": 57254304,
"subject_id": 19623993,
"report": "impression: No focal consolidation concerning for pneumonia. Findings: Mild linear atelectasis in the right lung is unchanged. There is no new\n consolidation, pleural effusion, or pneumothorax. The cardiomediastinal and\n hilar silhouettes are normal.",
"image_path": [
"p19/p19623993/s57254304/b85f7da5-828bea81-c7e95d37-4650d910-3c367fa4.jpg"
],
"split": "test"
},
{
"id": "a8c650ae-950b6c2f-15d23a79-9c74f29c-af076691",
"study_id": 55420918,
"subject_id": 16853729,
"report": "impression: 1. Increasing bibasilar opacities which could be seen with lower airway\n inflammation or infection, although developing bronchopneumonia is not\n entirely excluded. \n \n 2. Mild anterior wedge compression deformity of a vertebral body at the\n thoracolumbar junction, likely L1; although probably chronic, potentially\n increased somewhat. Findings: The heart is mildly enlarged with a left ventricular configuration.\n There is similar unfolding of the thoracic aorta. The mediastinal and hilar\n contours appear unchanged including a convexity along the right upper\n mediastinal contour. Particularly since it appears stable over time, it can\n probably be attributed to tortuosity of the great vessels. \n \n At both lung bases, but more extensive on the right than left, there are\n patchy opacities, fairly streaky in nature but extensive. These are increased\n since the earlier examination and are accompanied by peribronchial cuffing. \n There is no pleural effusion or pneumothorax. \n \n Suspected mild loss in mid thoracic vertebral body heights appears unchanged\n and probably coincides with demineralization. The lower thoracic spine shows\n mild rightward convex curvature. There is wedging of an upper lumbar\n vertebral body which may be increased somewhat, although the apparent\n difference may be due to differences in orientation.",
"image_path": [
"p16/p16853729/s55420918/a8c650ae-950b6c2f-15d23a79-9c74f29c-af076691.jpg"
],
"split": "test"
},
{
"id": "3056f052-ff3c284f-0d46f60a-7d4ee6af-498142fb",
"study_id": 50957430,
"subject_id": 12736592,
"report": "impression: Left-sided chest tube now seen with tip overlying the left lung\n apex. Findings: Single portable view of the chest at 4:57 p.m. is compared to\n previous exam from earlier the same day at 4:10 p.m. Left-sided chest tube is\n seen with tip projecting over the left lung apex. Although there is increased\n lucency in the left hemithorax, no discrete pleural line is identified based\n on this supine film. There is left chest wall subcutaneous gas seen. \n Otherwise, there has been no change.",
"image_path": [
"p12/p12736592/s50957430/3056f052-ff3c284f-0d46f60a-7d4ee6af-498142fb.jpg"
],
"split": "test"
},
{
"id": "0ac370ca-d14e45b3-07c05241-b3a551b3-4cde1652",
"study_id": 53598647,
"subject_id": 13881772,
"report": "impression: No acute findings. Findings: PA and lateral views of the chest were provided. Lungs are clear\n bilaterally. No effusion or pneumothorax is seen. Cardiomediastinal\n silhouette is stable. Bony structures are intact.",
"image_path": [
"p13/p13881772/s53598647/0ac370ca-d14e45b3-07c05241-b3a551b3-4cde1652.jpg"
],
"split": "test"
},
{
"id": "5b433593-d02544b5-225e12eb-2d963391-108a1692",
"study_id": 53504804,
"subject_id": 19844485,
"report": "impression: Increased opacity at the right lung base, likely a combination of\n effusion and atelectasis, though underlying pneumonia difficult to exclude. Findings: PA and lateral views of the chest were provided. Since the prior\n exam, there is increased opacity at the right lung base which could represent\n a combination of atelectasis and effusion, though underlying pneumonia is\n difficult to exclude in the correct clinical setting. Lung volumes and\n evaluation for mild pulmonary edema is limited. There is no overt edema. No\n pneumothorax is seen. Bony structures appear intact.",
"image_path": [
"p19/p19844485/s53504804/5b433593-d02544b5-225e12eb-2d963391-108a1692.jpg"
],
"split": "test"
},
{
"id": "4f69d69a-0a777d03-41d5250c-ecbbd9a2-72febcb8",
"study_id": 51788928,
"subject_id": 11293517,
"report": "impression: Resolution of cardiogenic pulmonary edema and right lower lobe\n consolidation. Findings: PA and lateral radiographs of the chest demonstrate interval\n resolution of pulmonary edema as well as the possible right lower lobe\n consolidation. Mild cardiomegaly is chronic. The upper mediastinum is now\n less widened, consistent with resolution of central vascular engorgement. \n There is no pneumothorax or pleural effusion. Pulmonary vascularity is\n normal. The atrial, biventricular ICD are unchanged.",
"image_path": [
"p11/p11293517/s51788928/4f69d69a-0a777d03-41d5250c-ecbbd9a2-72febcb8.jpg"
],
"split": "test"
},
{
"id": "5a43bc2b-3fc26154-5114dc49-e3d4f15e-459347eb",
"study_id": 55108847,
"subject_id": 11413236,
"report": "impression: Persistent left basilar opacification, suspected to represent\n primarily atelectasis. However, the possibility of superimposed pneumonia\n could be considered in the appropriate clinical setting versus increased\n atelectasis associated with low lung volumes. Findings: The patient is status post sternotomy. A Port-A-Cath terminates at\n the cavoatrial junction. The heart is at the upper limits of normal size. A\n calcified lymph node is seen along the aortopulmonary window. The cardiac,\n mediastinal and hilar contours do not appear significantly changed. The lung\n volumes are low. There is persistent patchy opacification in the left lower\n lobe, which appears somewhat more dense and compressed, perhaps coinciding\n with differences in lung volumes rather than a true interval change however. \n In fact, left basilar opacities are more similar to ___, where\n lungs volumes were somewhat lower than on the more recent prior examination. \n There is no pleural effusion or pneumothorax. Bony structures are\n unremarkable.",
"image_path": [
"p11/p11413236/s55108847/5a43bc2b-3fc26154-5114dc49-e3d4f15e-459347eb.jpg"
],
"split": "test"
},
{
"id": "7e530d0e-05f64408-24c921b8-1929b8f8-29ec99fd",
"study_id": 50247294,
"subject_id": 12433541,
"report": "impression: Stable appearance of the chest; no evidence of a superimposed\n acute process. Findings: Right hilar and perihilar opacification appears unchanged and\n suggests a site of treated malignancy. The cardiac, mediastinal and hilar\n contours appear unchanged. The lungs appear otherwise clear. There are no\n pleural effusions or pneumothorax.",
"image_path": [
"p12/p12433541/s50247294/7e530d0e-05f64408-24c921b8-1929b8f8-29ec99fd.jpg"
],
"split": "test"
},
{
"id": "369dc5bd-70bd89d0-2d90fa80-f319ec1d-fb2802aa",
"study_id": 53631792,
"subject_id": 18460230,
"report": "In comparison with study of ___, the monitoring and support devices remain\n unchanged. There appears to be some increasing haziness of the right\n hemithorax, which would be consistent with some increasing pleural effusion. \n However, this is difficult to assess since it could reflect changes in patient\n position.\n \n The pulmonary vessels appear more engorged than on the previous study and\n there continues to be substantial enlargement of the cardiac silhouette.",
"image_path": [
"p18/p18460230/s53631792/369dc5bd-70bd89d0-2d90fa80-f319ec1d-fb2802aa.jpg"
],
"split": "test"
},
{
"id": "3ecc5fc4-ddb10e6d-149d9bc0-0e810143-adbc6d0d",
"study_id": 56216565,
"subject_id": 15857729,
"report": "impression: Moderate cardiomegaly smaller since the prior study.\n Opacity projecting over the spine on the lateral radiograph may reflect\n pneumonia. Findings: The lungs are normally expanded except for mild atelectasis at the lung bases.\n Opacities project over the spine on the lateral radiograph. The heart is\n slightly smaller since the study of ___, however there is still\n moderate cardiomegaly. There is no pleural effusion or pneumothorax. There is\n no pulmonary edema. Mild rightward deviation of the trachea is likely\n secondary to known enlargement of the thyroid, left greater than right.",
"image_path": [
"p15/p15857729/s56216565/3ecc5fc4-ddb10e6d-149d9bc0-0e810143-adbc6d0d.jpg"
],
"split": "test"
},
{
"id": "904cf86f-1866f68d-e860512e-9cbe3c9e-f9c32a56",
"study_id": 54355585,
"subject_id": 15840907,
"report": "impression: No acute cardiopulmonary pathology. Findings: The cardiomediastinal and hilar contours\n are normal. The lungs are well expanded and clear, without focal\n consolidation, pleural effusion or pneumothorax. Mild degenerative changes\n are seen in the thoracic spine.",
"image_path": [
"p15/p15840907/s54355585/904cf86f-1866f68d-e860512e-9cbe3c9e-f9c32a56.jpg"
],
"split": "test"
},
{
"id": "d6051124-a16053dc-2b4ecb89-8e1a17a9-252c1e8f",
"study_id": 53183707,
"subject_id": 10274145,
"report": "impression: No evidence of pneumonia. Stable cardiomegaly. Findings: The lungs are clear bilaterally with\n no areas of focal consolidation. There is no pleural effusion or\n pneumothorax. Patient is status post CABG. Cardiomegaly is stable. \n Mediastinal silhouette is within normal limits.",
"image_path": [
"p10/p10274145/s53183707/d6051124-a16053dc-2b4ecb89-8e1a17a9-252c1e8f.jpg"
],
"split": "test"
},
{
"id": "4161612b-04b736ab-f5965aae-1028ae0b-6bf634ae",
"study_id": 58084217,
"subject_id": 16751749,
"report": "impression: Little change. Findings: Per chest x-ray small right apical pneumothorax is present. This area can now\n no longer be evaluated due to overlying subcutaneous emphysema.\n \n Few opacifications have been present on numerous previous films. There is an\n increased density around the right chest tube which was not present on the\n chest x-ray of ___ though was present on the prior chest x-ray of\n 4:00 a.m. This is thought to probably represent atelectasis but could\n represent an area of infection.",
"image_path": [
"p16/p16751749/s58084217/4161612b-04b736ab-f5965aae-1028ae0b-6bf634ae.jpg"
],
"split": "test"
},
{
"id": "848b0d7f-e95a86d4-0c40c933-7b2dc937-ac3d74c6",
"study_id": 56258422,
"subject_id": 11022245,
"report": "As compared to the previous radiograph, the right venous\n introduction sheath has been removed and a left PICC line has been inserted. \n The course of the line is unremarkable, the tip of the line projects over the\n mid SVC. There is no evidence of complications, notably no pneumothorax.\n \n The pre-existing bilateral parenchymal opacities, mostly caused by pleural\n effusions and subsequent atelectasis, have decreased in extent.",
"image_path": [
"p11/p11022245/s56258422/848b0d7f-e95a86d4-0c40c933-7b2dc937-ac3d74c6.jpg"
],
"split": "test"
},
{
"id": "a5e77ee2-5fec82c7-1f5ffe9c-ccd28c6b-f4a44978",
"study_id": 59369967,
"subject_id": 12963531,
"report": "Again seen is severe cardiomegaly with a globular configuration of\n the heart. The central venous catheter for dialysis is again visualized\n projecting over the right atrium. There are small bilateral pleural\n effusions, similar compared to prior. There is no focal infiltrate.",
"image_path": [
"p12/p12963531/s59369967/a5e77ee2-5fec82c7-1f5ffe9c-ccd28c6b-f4a44978.jpg"
],
"split": "test"
},
{
"id": "2f0faf68-27020330-24ac6180-f913331b-440b1474",
"study_id": 59502822,
"subject_id": 16957952,
"report": "impression: 1. No acute cardiopulmonary process.\n 2. Known L1 and L2 compression deformities. Findings: There is no focal consolidation, pleural effusion or pneumothorax. Streaky\n opacities at the left lung base is most likely due to atelectasis. \n Cardiomediastinal silhouette is within normal limits. Median sternotomy wires\n are intact. Known compression deformities of L1 and L2 are partially imaged.",
"image_path": [
"p16/p16957952/s59502822/2f0faf68-27020330-24ac6180-f913331b-440b1474.jpg"
],
"split": "test"
},
{
"id": "ba4bbaf8-52c6f0c8-d6922907-95d9b63b-f10069d0",
"study_id": 58773373,
"subject_id": 16772702,
"report": "impression: Interval improvement of the findings compatible with congestive\n failure when compared to previous exam from ___ with persistent\n bilateral left greater than right pleural effusions and pulmonary vascular\n congestion. Findings: Frontal and lateral views of the chest are compared to previous\n exam from ___. When compared to prior, there has been interval\n improvement in the appearance of the pulmonary edema. Indistinct pulmonary\n vascular markings persist as well as small right and moderate left pleural\n effusions. Cardiac silhouette is enlarged but stable in configuration. \n Osseous and soft tissue structures are unchanged.",
"image_path": [
"p16/p16772702/s58773373/ba4bbaf8-52c6f0c8-d6922907-95d9b63b-f10069d0.jpg"
],
"split": "test"
},
{
"id": "3d5c9bad-c1fa71ed-adc295a3-b423edd6-afb265b0",
"study_id": 52279876,
"subject_id": 19765968,
"report": "impression: Little change in diffuse interstitial prominence, without new\n focal parenchymal opacity. Chronic osseous changes involving the distal right\n clavicle and mid-thoracic vertebral bodies are again noted. Findings: A mild diffuse interstitial abnormality persists, possibly reflecting known\n airways abnormalities previously imaged by CT. There are no new focal\n opacities. No effusion and no pneumothorax. The hilar and cardiomediastinal\n contours are unchanged. There is no pulmonary vascular congestion or\n pulmonary edema. Chronic deformity of the distal right clavicle is unchanged\n from prior studies. There is mild compression deformity of two mid-thoracic\n vertebral bodies, similarly stable. No new fractures are identified.",
"image_path": [
"p19/p19765968/s52279876/3d5c9bad-c1fa71ed-adc295a3-b423edd6-afb265b0.jpg"
],
"split": "test"
},
{
"id": "7f90be03-f64f2d0b-36350e78-668756f9-417c5b45",
"study_id": 51323886,
"subject_id": 19759491,
"report": "impression: 1. Stable pulmonary vascular congestion and interstitial edema.\n 2. Left lung base opacity is probably due to a combination of small left\n pleural effusion and adjacent atelectasis. Findings: There is no significant interval change since the prior radiograph performed\n yesterday evening. A biventricular pacer defibrillator is visualized. The\n hemodialysis catheter is unchanged in position and terminates in the right\n atrium.\n \n There is persistent mild pulmonary vascular congestion accompanied by\n interstitial pulmonary edema. No new areas of focal consolidation are\n identified. Left lung base opacity is probably due to a combination of a\n small pleural effusion and adjacent atelectasis. A small right pleural\n effusion is also noted. Stable cardiomegaly.",
"image_path": [
"p19/p19759491/s51323886/7f90be03-f64f2d0b-36350e78-668756f9-417c5b45.jpg"
],
"split": "test"
},
{
"id": "22353454-97e7e0d1-d2711b39-b8159585-512d3c23",
"study_id": 59847128,
"subject_id": 19182863,
"report": "Left PICC is unchanged in position compared to the prior\n radiograph. It enters via a left-sided approach, and makes a vertical descent\n at the level of the aortic arch, in keeping with known left-sided superior\n vena cava. The tip of the catheter continues to terminate just above the\n level of the diaphragm to the left of midline, and could be withdrawn\n approximately 8 cm to ensure positioning within the lower left superior vena\n cava. Cardiomediastinal contours are stable in appearance. Moderate right\n pleural effusion with subpulmonic component has slightly increased in size. \n Adjacent area of opacity within the right middle and lower lobe has also\n slightly worsened.",
"image_path": [
"p19/p19182863/s59847128/22353454-97e7e0d1-d2711b39-b8159585-512d3c23.jpg"
],
"split": "test"
},
{
"id": "e872e235-dee5ac10-dfd4a5e4-e40a9a02-73e5ee8a",
"study_id": 52072042,
"subject_id": 17257913,
"report": "As compared to the previous radiograph, there is no relevant\n change. Relatively wide mediastinum, caused by mediastinal lipomatosis\n (documented on a PET-CT examination from ___). Borderline size of\n the cardiac silhouette. No evidence of pleural effusion, pulmonary edema, or\n pneumonia. No pneumothorax.",
"image_path": [
"p17/p17257913/s52072042/e872e235-dee5ac10-dfd4a5e4-e40a9a02-73e5ee8a.jpg"
],
"split": "test"
},
{
"id": "02b9665e-286a47a7-edbf1119-14117e3b-ed29a2fe",
"study_id": 58057712,
"subject_id": 14841168,
"report": "As compared to the previous radiograph, there is no relevant\n change. The monitoring and support devices are in unchanged position. \n Moderate cardiomegaly with moderate right pleural effusion, accompanied by\n areas of bilateral basal atelectasis, right more than left. Mild fluid\n overload. No newly appeared parenchymal opacities.",
"image_path": [
"p14/p14841168/s58057712/02b9665e-286a47a7-edbf1119-14117e3b-ed29a2fe.jpg"
],
"split": "test"
},
{
"id": "596ada03-4cd1298c-35965d3c-db44850a-0baa9257",
"study_id": 59509358,
"subject_id": 19061282,
"report": "impression: Bilateral parenchymal opacities, right greater than left compatible with\n pneumonia in the proper clinical setting. Findings: There bilateral regions of consolidation, at the right lung and left mid to\n lower lung. Findings are most concerning for bilateral infection. Moderate\n enlargement of the cardiac silhouette is unchanged. Multiple vascular stents\n are also noted. No acute osseous abnormalities. Splenic calcifications are\n again noted.",
"image_path": [
"p19/p19061282/s59509358/596ada03-4cd1298c-35965d3c-db44850a-0baa9257.jpg"
],
"split": "test"
},
{
"id": "d09562d7-3ddb8397-a8101476-43ad0118-5fae5eb9",
"study_id": 57848354,
"subject_id": 11474065,
"report": "In comparison with the study of ___, there is again evidence of\n mild pulmonary edema, more prominent on the right. More focal area of\n opacification at the base medially with poor definition of the right heart\n border raises the possibility of a middle lobe pneumonia. Right pleural\n thickening or loculated effusion is again seen.",
"image_path": [
"p11/p11474065/s57848354/d09562d7-3ddb8397-a8101476-43ad0118-5fae5eb9.jpg"
],
"split": "test"
},
{
"id": "a19573c3-98f76c03-5552fc10-4d2cb79e-bce663a8",
"study_id": 56373739,
"subject_id": 12952223,
"report": "Compared to the previous radiograph, the monitoring and support\n devices are unchanged. A pre-existing right pleural effusion has slightly\n increased in extent. Subsequent areas of atelectasis are bilaterally\n constant. Constant appearance of the cardiac silhouette. No hilar or\n mediastinal abnormalities.",
"image_path": [
"p12/p12952223/s56373739/a19573c3-98f76c03-5552fc10-4d2cb79e-bce663a8.jpg"
],
"split": "test"
},
{
"id": "b06d47bc-8181cd72-254ab8b4-1731873e-41b7aed5",
"study_id": 55746776,
"subject_id": 15857729,
"report": "impression: No evidence of pneumonia. Clear lungs. Findings: Subtle linear opacity in the right upper lobe likely represents atelectasis. \n The lungs are otherwise clear. The hilar and cardiomediastinal contours are\n normal. There is no pneumothorax or pleural effusion. Pulmonary vascularity\n is normal.",
"image_path": [
"p15/p15857729/s55746776/b06d47bc-8181cd72-254ab8b4-1731873e-41b7aed5.jpg"
],
"split": "test"
},
{
"id": "51f5ce00-6a5bde30-814d9207-cc5f7a52-ceb3502a",
"study_id": 57456610,
"subject_id": 19028690,
"report": "impression: New right IJ line. No pneumothorax. Findings: Single portable view of the chest. There is a new right IJ central line with\n tip in the mid SVC. There is no pneumothorax. The lungs remain clear. \n Azygous fissure again noted. Cardiomediastinal silhouette is stable noting\n prominence of the upper mediastinum due to fat, unchanged.",
"image_path": [
"p19/p19028690/s57456610/51f5ce00-6a5bde30-814d9207-cc5f7a52-ceb3502a.jpg"
],
"split": "test"
},
{
"id": "03502481-6cda13ba-cb388ede-fbd7eb62-5b02b608",
"study_id": 53574399,
"subject_id": 17340686,
"report": "impression: Mild to moderate pulmonary edema, similar compared to the prior study, with\n more focal opacity in the right lung base concerning for an area of infection. Findings: Left-sided dual lumen dialysis catheter tip terminates in the proximal right\n atrium, unchanged. The heart is mild to moderately enlarged with left atrial\n prominence. Mediastinal contours are unchanged. There is mild to moderate\n moderate pulmonary edema, with more focal opacity seen in the right lung base,\n new from the prior study. Small bilateral pleural effusions are noted. There\n is no pneumothorax. No acute osseous abnormalities are visualized. Clips are\n seen within the upper abdomen.",
"image_path": [
"p17/p17340686/s53574399/03502481-6cda13ba-cb388ede-fbd7eb62-5b02b608.jpg"
],
"split": "test"
},
{
"id": "8b277408-532884e8-ea3f5ba6-e619ee5e-8c820c0c",
"study_id": 57883497,
"subject_id": 19454978,
"report": "Right PICC terminates in the lower superior vena cava. Right\n internal jugular catheter has been removed, with no visible pneumothorax. \n Otherwise, similar radiographic appearance of the chest since recent study.",
"image_path": [
"p19/p19454978/s57883497/8b277408-532884e8-ea3f5ba6-e619ee5e-8c820c0c.jpg"
],
"split": "test"
},
{
"id": "64c4f3ac-5b12f9d8-de62c4d5-1980be49-28cd96f9",
"study_id": 50139124,
"subject_id": 18079481,
"report": "As compared to the previous radiograph, the Dobbhoff catheter was\n advanced. The tip now projects over the proximal parts of the stomach, there\n is no evidence of complication, notably no pneumothorax. Otherwise, the\n radiograph is unchanged.",
"image_path": [
"p18/p18079481/s50139124/64c4f3ac-5b12f9d8-de62c4d5-1980be49-28cd96f9.jpg"
],
"split": "test"
},
{
"id": "14a4a35d-8763ba28-085afc05-45f80848-08962597",
"study_id": 54716295,
"subject_id": 18487334,
"report": "impression: Enteric tube tip in the proximal stomach Findings: Enteric tube tip in the proximal stomach. Right IJ line tip mid SVC. \n Endotracheal tube tip in good position. Sternotomy. There is cardiac\n pacemaker. Minimal new left basilar atelectasis. Suggestion of tiny left\n pleural effusion.",
"image_path": [
"p18/p18487334/s54716295/14a4a35d-8763ba28-085afc05-45f80848-08962597.jpg"
],
"split": "test"
},
{
"id": "ff9fed32-307dfd9e-3f70b114-c9234fbc-6a057052",
"study_id": 56997833,
"subject_id": 14851532,
"report": "impression: Re- demonstration of multifocal parenchymal opacities compatible with\n adenocarcinoma, better assessed on the previous CT. No acute cardiopulmonary\n abnormality. Findings: Cardiac silhouette size remains mildly enlarged and multiple mediastinal clips\n from prior CABG are again noted. The aorta remains tortuous and diffusely\n calcified. Pulmonary vasculature is not engorged. Hilar contours are\n similar. Ill-defined focal opacities are again noted within both upper lobes\n as well as within the left lower lobe, not substantially changed in the\n interval, and better assessed on the previous CT. No new focal consolidation,\n pleural effusion or pneumothorax is present. No acute osseous abnormalities\n detected. Clips are noted within the midline upper abdomen.",
"image_path": [
"p14/p14851532/s56997833/ff9fed32-307dfd9e-3f70b114-c9234fbc-6a057052.jpg"
],
"split": "test"
},
{
"id": "3d99ed96-dc2263d9-e1073168-b827579b-63b897ec",
"study_id": 51339993,
"subject_id": 16848073,
"report": "impression: 1. Worsening of the patient's pulmonary edema, more severe on the right than\n on the left.\n 2. Bibasilar pleural effusions with compressive atelectasis. Findings: There has been interval increase in the pulmonary edema, greater on\n the right than on the left. There are bilateral small pleural effusions with\n compressive atelectasis. There is stable widening of the mediastinum. A\n right chest tube is seen and unchanged from the prior exams. There are\n multiple overlying wires. The cardiomediastinal silhouette is unchanged.",
"image_path": [
"p16/p16848073/s51339993/3d99ed96-dc2263d9-e1073168-b827579b-63b897ec.jpg"
],
"split": "test"
},
{
"id": "aa20f78f-53dce569-e7263012-3c4ab839-7abbabd4",
"study_id": 54392033,
"subject_id": 18978682,
"report": "Comparison is made to prior study from ___.\n \n There is a right-sided PICC line with distal lead tip at the cavoatrial\n junction. There are low lung volumes with atelectasis at the lung bases and a\n left retrocardiac opacity. This is unchanged. Surgical clips within the left\n axilla are again seen. There are several healed old right-sided rib\n fractures. No pneumothoraces are seen.",
"image_path": [
"p18/p18978682/s54392033/aa20f78f-53dce569-e7263012-3c4ab839-7abbabd4.jpg"
],
"split": "test"
},
{
"id": "92c1d255-50a94318-0d4def6d-64a46468-3233bb79",
"study_id": 55372843,
"subject_id": 11052935,
"report": "impression: 1. No acute intrathoracic process.\n 2. Small focal opacity projects over the lateral right lower hemithorax.\n Shallow obliques off the frontal view are recommended for further evaluation.\n \n Findings and recommendations discussed with Dr. ___ (covering for\n Dr. ___, ___ by phone at ___:___pm ___. Findings: Frontal and lateral views of the chest were obtained. The lungs\n are hyperinflated. There is no focal consolidation, pleural effusion or\n pneumothorax. Small focal opacity projects over the lateral right lower\n hemithorax, may represent overlapping structures, but further evaluation is\n recommended with shallow obliques to assess for possible pulmonary nodule. \n Heart size is normal. Mediastinal silhouette and hilar contours are normal.",
"image_path": [
"p11/p11052935/s55372843/92c1d255-50a94318-0d4def6d-64a46468-3233bb79.jpg"
],
"split": "test"
},
{
"id": "80f8c1cf-51619e01-2da83861-7c12a49d-f6858e53",
"study_id": 57801123,
"subject_id": 18088200,
"report": "impression: No evidence of acute disease. Findings: The patient is status post sternotomy and probably coronary artery\n bypass graft surgery. The heart is mildly enlarged. The mediastinal and\n hilar contours appear unchanged, including a prominent left-sided epicardial\n fat pad. The lung volumes are low. Streaky lingular opacity suggesting minor\n atelectasis or scarring appears unchanged. Minimal blunting of the right\n costophrenic sulcus is more suggestive of similar slight atelectatic change,\n less likely persistent trace pleural effusion. There has been no significant\n change.",
"image_path": [
"p18/p18088200/s57801123/80f8c1cf-51619e01-2da83861-7c12a49d-f6858e53.jpg"
],
"split": "test"
},
{
"id": "8aa4f925-9b6e30c1-526619f6-79135e41-713c105c",
"study_id": 50255843,
"subject_id": 17270742,
"report": "impression: 1. Cavitary lesions in the right lung, consistent with known aspergillosis,\n with interval increase in the size of the largest lesion since ___.\n 2. Stable multifocal ground glass opacities, with more confluent consolidation\n in the left upper lobe. Findings: Again seen are two cavitary lesions in the\n right lung, with the largest in the right perihilar region, now measuring at\n least 14 cm in craniocaudal ___. This lesion is slightly larger since\n the prior study where it measured 11 cm. An airfluid level is seen in this\n lesion. The smaller cavitary lesion in the right upper lobe is stable. No new\n cavitary lesion is seen. Multiple areas of ground glass opacities, with more\n confluent consolidation in the left upper lobe are similar to the prior CT. No\n pleural effusions or pneumothorax is seen.",
"image_path": [
"p17/p17270742/s50255843/8aa4f925-9b6e30c1-526619f6-79135e41-713c105c.jpg"
],
"split": "test"
},
{
"id": "a8b7cbef-ae8ef4b0-09766f27-a49a3af2-eea22021",
"study_id": 55596851,
"subject_id": 19765968,
"report": "In comparison with study of ___, there is little change. There\n may be some minimal residual elevation of pulmonary venous pressure and small\n pleural effusion with bibasilar atelectasis. Central catheter remains in\n place.",
"image_path": [
"p19/p19765968/s55596851/a8b7cbef-ae8ef4b0-09766f27-a49a3af2-eea22021.jpg"
],
"split": "test"
},
{
"id": "c11e9140-f4243636-254f1c94-23fa1f6b-4efd76bf",
"study_id": 54773340,
"subject_id": 10449297,
"report": "impression: Pulmonary edema. Findings: Comparison is made to ___. In\n comparison to prior exam, there is increase in the vascular markings\n consistent with cardiac failure. No sizeable pleural effusion. \n Cardiomediastinal silhouette is top normal in size. The lungs show no focal\n opacities concerning for an infectious process. Compression deformity at\n approximate T12 vertebrae.",
"image_path": [
"p10/p10449297/s54773340/c11e9140-f4243636-254f1c94-23fa1f6b-4efd76bf.jpg"
],
"split": "test"
},
{
"id": "09eef487-ce5f18a5-ba553a04-30f2617c-4f4a6692",
"study_id": 59688743,
"subject_id": 15114531,
"report": "impression: No focal pneumonia. Findings: The right PICC has been removed in the interim. The lungs are well-expanded\n and clear. No focal consolidation, effusion, edema, or pneumothorax. The\n heart size is normal. The mediastinum is not widened. Surgical clips project\n over the left upper quadrant, unchanged. Anterior spinal fixation in the\n lower cervical spine is partially imaged. Multilevel degenerative changes in\n the thoracic spine are mild. Rightward curvature of the thoracic spine could\n be positional though was also present on ___.",
"image_path": [
"p15/p15114531/s59688743/09eef487-ce5f18a5-ba553a04-30f2617c-4f4a6692.jpg"
],
"split": "test"
},
{
"id": "4eab5702-5e51a961-a59e4e84-b5aa758f-4e367b89",
"study_id": 52841174,
"subject_id": 17669276,
"report": "impression: Mild interstitial edema, stable cardiomegaly with small bilateral\n effusions. Findings: AP upright and lateral views of the chest were provided. Midline\n sternotomy wires are again noted. Patient is rotated somewhat limiting the\n evaluation of the cardiomediastinal silhouette, though cardiomediastinal\n silhouette appears grossly stable. There are small layering bilateral\n effusions with mild interstitial edema. Overall, there has been no\n significant change from prior study. Bony structures are intact.",
"image_path": [
"p17/p17669276/s52841174/4eab5702-5e51a961-a59e4e84-b5aa758f-4e367b89.jpg"
],
"split": "test"
},
{
"id": "2a262a8c-c8739dde-30e57c4d-800f4b3a-51d54c14",
"study_id": 50966773,
"subject_id": 13921768,
"report": "impression: 1. There is mild vascular congestion consistent with mild fluid overload.\n \n 2. Opacification of the right upper lung could be due to asymmetric pulmonary\n edema, scapula projecting over the lung or in the appropriate clinical setting\n pneumonia.\n \n 3. Small, bilateral pleural effusions and associated bibasilar atelectasis. Findings: Single AP view of the chest provided.\n \n A right atrioventricular pacemaker appears unchanged.\n \n The right lung is hypoinflated in relation to the left lung. There is mild\n vascular congestion consistent with fluid overload.\n \n No pneumothorax. Small, bilateral pleural effusions are seen with associated\n bibasilar atelectasis.\n \n Hilar contours are normal. The aorta is tortuous.\n \n Severe S-shaped is unchanged.",
"image_path": [
"p13/p13921768/s50966773/2a262a8c-c8739dde-30e57c4d-800f4b3a-51d54c14.jpg"
],
"split": "test"
},
{
"id": "f1e6712c-61dabae0-6691539a-039dcbb7-6c467216",
"study_id": 52937462,
"subject_id": 10885696,
"report": "impression: Right lower lobe opacity with volume loss, likely atelectasis,\n unchanged since the earlier study of ___. Findings: The cardiomediastinal and hilar contours\n are stable, with stable enlargement of the left pulmonary artery superimposed\n over the left upper lung. Streaky opacities and volume loss in the right\n lower lobe, likely atelectasis, have been stable since the prior studies. No\n new consolidation, pulmonary edema, pleural effusion or pneumothorax is seen. \n There is stable volume loss in the left lung secondary to prior lobectomy.",
"image_path": [
"p10/p10885696/s52937462/f1e6712c-61dabae0-6691539a-039dcbb7-6c467216.jpg"
],
"split": "test"
},
{
"id": "9dbf45cb-e6b01b87-76e4d3db-7a480daf-192bce3b",
"study_id": 57001251,
"subject_id": 11293517,
"report": "impression: New bibasilar opacities could represent atelectasis, sequelae of aspiration or\n pneumonia. Findings: The lungs are well expanded and show a new right and left lower lobe opacity. \n The cardiac silhouette is enlarged, unchanged. The mediastinal silhouette and\n hilar contours are unremarkable. No pleural effusion or pneumothorax is\n present. Multiple right ventricular and right atrium leads are noted,\n unchanged. A left-sided pacer is also unchanged in position.",
"image_path": [
"p11/p11293517/s57001251/9dbf45cb-e6b01b87-76e4d3db-7a480daf-192bce3b.jpg"
],
"split": "test"
},
{
"id": "1de015eb-891f1b02-f90be378-d6af1e86-df3270c2",
"study_id": 57171514,
"subject_id": 11052935,
"report": "impression: No acute cardiopulmonary process. Findings: Single portable view of the chest. The lungs are hyperinflated but clear of\n consolidation. The cardiomediastinal silhouette is within normal limits. \n Osseous structures are unremarkable.",
"image_path": [
"p11/p11052935/s57171514/1de015eb-891f1b02-f90be378-d6af1e86-df3270c2.jpg"
],
"split": "test"
},
{
"id": "7491ba73-b81aa431-0b41a7cb-733d87f1-4523ba29",
"study_id": 59225625,
"subject_id": 10933609,
"report": "impression: Multifocal regions of consolidation, new since exam from two\n weeks prior, compatible with pneumonia in the proper clinical setting. \n Recommend repeat after treatment to document resolution. Findings: Frontal and lateral views of the chest are compared to previous\n exam from ___. There is new multifocal consolidation in the right\n upper lobe, within the right perihilar region and possibly in the retrocardiac\n region as well. Lungs are otherwise notable for parenchymal architectural\n distortion at the upper lungs bilaterally. There is no effusion. \n Cardiomediastinal silhouette is within normal limits. Osseous and soft tissue\n structures are unremarkable.",
"image_path": [
"p10/p10933609/s59225625/7491ba73-b81aa431-0b41a7cb-733d87f1-4523ba29.jpg"
],
"split": "test"
},
{
"id": "449aaf0d-39419c16-a79e10d0-a6d3b8b1-1076c60f",
"study_id": 50291999,
"subject_id": 12595991,
"report": "impression: Moderate cardiomegaly with AICD in unchanged position. No evidence of\n congestive heart failure or pneumonia. Findings: PA and lateral views of the chest provided demonstrate an AICD projecting over\n the left chest wall with leads extending into the region of the right atrium,\n right ventricle, and coronary sinus. Cardiomegaly is moderate. The lungs are\n clear. No pleural effusion or pneumothorax. Atherosclerotic calcification at\n the aortic knob. Bony structures intact. No free air below the right\n hemidiaphragm.",
"image_path": [
"p12/p12595991/s50291999/449aaf0d-39419c16-a79e10d0-a6d3b8b1-1076c60f.jpg"
],
"split": "test"
},
{
"id": "24960743-14f426d7-d057ceaa-ea719e12-5534250a",
"study_id": 56233609,
"subject_id": 18767957,
"report": "impression: No significant interval change. Findings: There has been no significant interval change. The cardiac and mediastinal\n silhouettes are stable. Hilar contours are stable with possible minimal\n central vascular engorgement.",
"image_path": [
"p18/p18767957/s56233609/24960743-14f426d7-d057ceaa-ea719e12-5534250a.jpg"
],
"split": "test"
},
{
"id": "3c333c52-c86e232a-705001ae-b328c40c-41096f34",
"study_id": 59873070,
"subject_id": 13352405,
"report": "As compared to the previous examination from ___, the\n rounded pleural opacity (should not be mistaken for a mass) on the right,\n caused by encapsulated pleural effusion, has almost completely resolved. The\n right pleural effusion has decreased in extent. However, there is elevation\n of the hemidiaphragm, a small basal pleural effusion and subsequent areas of\n atelectasis.\n \n On the left, the lung parenchyma now appears normal. Healed left rib\n fractures are visible. Normal size of the cardiac silhouette. Mild\n tortuosity of the thoracic aorta.",
"image_path": [
"p13/p13352405/s59873070/3c333c52-c86e232a-705001ae-b328c40c-41096f34.jpg"
],
"split": "test"
},
{
"id": "e6298e5b-366c6725-3be73135-100fb888-3168c3b2",
"study_id": 52052294,
"subject_id": 16050730,
"report": "In comparison with the study of ___, the hand of the patient\n obscures the lower half of the left chest. There is enlargement of the\n cardiac silhouette with indistinctness of engorged pulmonary vessels,\n consistent with elevated pulmonary venous pressure. In the appropriate\n clinical setting, superimposed basilar pneumonia could be considered.",
"image_path": [
"p16/p16050730/s52052294/e6298e5b-366c6725-3be73135-100fb888-3168c3b2.jpg"
],
"split": "test"
},
{
"id": "60ac55ad-b8bf8c04-356991fb-91f18417-83b359fa",
"study_id": 51882937,
"subject_id": 11052935,
"report": "impression: 1. Possible early right lower lobe pneumonia.\n 2. Left upper lobe scarring from prior pneumonia.\n 3. Findings consistent with COPD. Findings: PA and lateral chest radiographs were provided. There is a subtle\n opacity in the right lower lobe that is concerning for early pneumonia. There\n is linear scarring in the left upper lobe from area of prior pneumonia that\n has resolved. The lungs are hyperinflated and the diaphragms are flattened,\n consistent with COPD. There is no pleural effusion or pneumothorax. The\n cardiomediastinal silhouette is unremarkable. There is no free air under the\n right hemidiaphragm. There are no acute osseous lesions.",
"image_path": [
"p11/p11052935/s51882937/60ac55ad-b8bf8c04-356991fb-91f18417-83b359fa.jpg"
],
"split": "test"
},
{
"id": "d9c359c1-1be4d372-89b1a633-8ae85c64-d875118f",
"study_id": 59804376,
"subject_id": 16334516,
"report": "impression: No acute cardiothoracic process including no evidence of\n pneumonia. Findings: A longstanding left upper lobe oval nodule has been present since at\n least ___ and has not changed since at least ___ when a Chest CT report\n termed it benign. Sclerosis at the right first costochondral junction as well\n as post-surgical changes from a wedge resection in the right upper lobe are\n all stable since ___.\n The cardiomediastinal silhouette and hila are normal. There is no pleural\n effusion and no pneumothorax. Mild pulmonary vascular congestion is chronic or\n recurrent.",
"image_path": [
"p16/p16334516/s59804376/d9c359c1-1be4d372-89b1a633-8ae85c64-d875118f.jpg"
],
"split": "test"
},
{
"id": "20c5c50c-553e3e49-0736e206-832e3377-9d7f8937",
"study_id": 55946640,
"subject_id": 19016834,
"report": "impression: COPD, scarring at the right lung base. No definite signs of\n pneumonia or CHF. Findings: PA and lateral views of the chest were obtained. The lungs are\n hyperinflated with markedly widened AP diameter of the chest which is\n compatible with emphysema. An area of presumed scarring at the right lung\n base appears stable from most recent prior exam. There is no new\n consolidation, effusion, or pneumothorax seen. Cardiomediastinal silhouette\n appears stable. Bony structures intact.",
"image_path": [
"p19/p19016834/s55946640/20c5c50c-553e3e49-0736e206-832e3377-9d7f8937.jpg"
],
"split": "test"
},
{
"id": "0844862c-b31ad664-cb39e0fe-f457cc37-02e1b4ae",
"study_id": 51718410,
"subject_id": 13263843,
"report": "impression: There is no pneumothorax after pigtail placement. \n Right subpulmonic pleural effusion has significantly improved. Findings: New pigtail is in right lower hemithorax with significant improvement of\n subpulmonic effusion. Left lower lung pneumonia with small pleural effusion\n is slightly worse than ___ but improved since ___. \n Patient had right upper lobe lobectomy and radiation therapy for cancer, this\n was better assessed in recent CT scan.",
"image_path": [
"p13/p13263843/s51718410/0844862c-b31ad664-cb39e0fe-f457cc37-02e1b4ae.jpg"
],
"split": "test"
},
{
"id": "ac2bc5fb-c181f807-907ef393-692441ee-057ffb40",
"study_id": 50319774,
"subject_id": 13473495,
"report": "impression: Pulmonary vascular congestion, slightly worse in the interval. Findings: Severe cardiomegaly persists. A left subclavian vascular stent is re-\n demonstrated. Mediastinal contours are unchanged. There is pulmonary\n vascular congestion,slightly worse in the interval. A small amount of fluid\n is noted within the minor fissure. No focal consolidation, pleural effusion\n or pneumothorax is demonstrated.",
"image_path": [
"p13/p13473495/s50319774/ac2bc5fb-c181f807-907ef393-692441ee-057ffb40.jpg"
],
"split": "test"
},
{
"id": "dce92976-fb96a7c4-c9a1da62-474592a5-98203d87",
"study_id": 52702994,
"subject_id": 14744884,
"report": "impression: No acute cardiopulmonary process. Findings: The lungs are clear. Cardiomediastinal and hilar\n contours are normal. Right subclavian/brachiocephalic venous stents unchanged\n in position. There are no pleural effusions or pneumothorax.",
"image_path": [
"p14/p14744884/s52702994/dce92976-fb96a7c4-c9a1da62-474592a5-98203d87.jpg"
],
"split": "test"
},
{
"id": "d395c594-96025cff-7e6af4ad-ca08ac10-032bd500",
"study_id": 54023727,
"subject_id": 14387068,
"report": "In comparison with study of ___, the Dobbhoff tube has been pulled\n back somewhat. The opaque tip is in the mid body of the stomach, pointing\n laterally.\n \n Little overall change in the appearance of the heart and lungs.",
"image_path": [
"p14/p14387068/s54023727/d395c594-96025cff-7e6af4ad-ca08ac10-032bd500.jpg"
],
"split": "test"
},
{
"id": "232aed3a-74900285-3fa279f4-43c5af2a-e8406c03",
"study_id": 51986565,
"subject_id": 15114531,
"report": "impression: Persistent subtle peribronchial opacity in left lung is worrisome for early\n pneumonia in the appropriate clinical setting. Findings: Lungs are well inflated. Mild bilateral apical scarring noted. Subtle\n peribronchial opacity only seen on frontal view in the left lung superior and\n lateral to the left hilus is unchanged since prior examination. The lungs are\n otherwise clear. No pleural effusion or pneumothorax. Heart size,\n mediastinal contour, and hila are unremarkable.\n \n Visualized osseous structures are notable for anterior cervical spine fusion\n device. Mediastinal clips are again seen within the left upper quadrant.",
"image_path": [
"p15/p15114531/s51986565/232aed3a-74900285-3fa279f4-43c5af2a-e8406c03.jpg"
],
"split": "test"
},
{
"id": "09a3e9d9-822e7d52-af47f424-1f87a789-2edd0300",
"study_id": 53607277,
"subject_id": 16773796,
"report": "impression: Innumerable pulmonary metastases and migrated esophageal stents, residing\n within the stomach, without evidence of acute process. Findings: 2 views were obtained of the chest. Innumerable pulmonary metastases are\n re-demonstrated and better assessed on the recent CT without intervally\n developed focal consolidation, pleural effusion or pneumothorax. The\n esophageal stents again project over the upper abdomen consistent migration\n into the stomach as depicted on the recent CT. The heart and mediastinal\n contours are unchanged with postsurgical changes noted in the mediastinum. \n Osseous abnormalities described in the recent CT are not well assessed on the\n current examination.",
"image_path": [
"p16/p16773796/s53607277/09a3e9d9-822e7d52-af47f424-1f87a789-2edd0300.jpg"
],
"split": "test"
},
{
"id": "f3f953d7-e6a719c7-2e5e731b-3181955e-30e32f42",
"study_id": 59022336,
"subject_id": 14727722,
"report": "In comparison with the study of ___, there is little change and\n no evidence of acute cardiopulmonary disease. No pneumonia, vascular\n congestion, or pleural effusion. The cardiac silhouette is at the upper\n limits of normal in size or slightly enlarged.",
"image_path": [
"p14/p14727722/s59022336/f3f953d7-e6a719c7-2e5e731b-3181955e-30e32f42.jpg"
],
"split": "test"
},
{
"id": "8137d98b-e8a60482-a158cc07-096a8d02-978fa0cc",
"study_id": 55167068,
"subject_id": 14851532,
"report": "impression: Interval increase in interstitial markings bilaterally since the\n prior study raises concern for worsening pulmonary edema.\n \n Small right pleural effusion, better assessed on preceding CT.\n \n Left lower lobe opacities better seen on CT Findings: The cardiac silhouette remains mildly enlarged. In the interval\n since the prior study, there is increase in interstitial markings bilaterally,\n particularly centrally, worrisome for worsening pulmonary edema. Right\n basilar opacity is again seen, which may be due to fluid overload, although an\n underlying consolidation is not excluded. Small right pleural effusion was\n better seen on CT as was left lower lobe opacities. Surgical clips are noted\n overlying the left upper mediastinum. Aortic knob calcifications again seen.",
"image_path": [
"p14/p14851532/s55167068/8137d98b-e8a60482-a158cc07-096a8d02-978fa0cc.jpg"
],
"split": "test"
},
{
"id": "871b39ac-d22367db-2644f680-703ffc97-e29ad517",
"study_id": 59560734,
"subject_id": 13849733,
"report": "impression: Stable layering moderate right pleural effusion since ___. Findings: There are stable fibrotic changes involving both lungs with left\n apical scarring related to known prior tuberculosis exposure. There is a\n stable moderate layering right pleural effusion since ___. There are\n no new focally occurring parenchymal opacities concerning for pneumonia. \n There is no evidence of pneumothorax. Cardiomediastinal and hilar contours\n are stable, with heart size within the upper limits of normal. Pulmonary\n vascularity is not increased.",
"image_path": [
"p13/p13849733/s59560734/871b39ac-d22367db-2644f680-703ffc97-e29ad517.jpg"
],
"split": "test"
},
{
"id": "08a8deab-aa27ad50-256fe6f1-21da6275-363a878d",
"study_id": 57802287,
"subject_id": 10410641,
"report": "Pigtail pleural catheters remain in place bilaterally. Small\n bilateral apical lateral pneumothoraces have slightly decreased in size since\n the prior study. Small left pleural effusion is again demonstrated.",
"image_path": [
"p10/p10410641/s57802287/08a8deab-aa27ad50-256fe6f1-21da6275-363a878d.jpg"
],
"split": "test"
},
{
"id": "960b69b4-844f9fbb-2fe99d01-27e23cb6-c4a78097",
"study_id": 55693842,
"subject_id": 14387068,
"report": "Comparison is made to previous study from ___.\n \n There is a right-sided central venous line with distal tip at the cavoatrial\n junction. There is a feeding tube whose distal tip is below the GE junction. \n There is air-fluid level projecting over the right lower lobe consistent with\n the patient's known empyema. The pigtail catheter at the right base is no\n longer seen. There is also a left-sided small pleural effusion. No\n pneumothoraces are seen.",
"image_path": [
"p14/p14387068/s55693842/960b69b4-844f9fbb-2fe99d01-27e23cb6-c4a78097.jpg"
],
"split": "test"
},
{
"id": "6ec78bca-9eb86302-16367715-1a68dd88-f70084c0",
"study_id": 58641137,
"subject_id": 17032538,
"report": "Endotracheal tube terminates approximately 3.4 cm above the carina and is\n adequately positioned. Feeding tube is seen to course below the diaphragm\n into the stomach; however, distal end is out of the radiographic view.\n \n Right mid and lower lung and left lower lung opacities concerning for\n multifocal pneumonia have worsened since ___. An coexisting\n component pulmonary edema is possible. No other interval changes. Scarring in\n the right lower lungs and right apical dense pleural thickening are unchanged.\n Small bilateral pleural effusions are similar. No pneumothorax.",
"image_path": [
"p17/p17032538/s58641137/6ec78bca-9eb86302-16367715-1a68dd88-f70084c0.jpg"
],
"split": "test"
},
{
"id": "9c44b35d-68d09c0c-3cfbce66-0341de07-1c0346ee",
"study_id": 52356321,
"subject_id": 11607628,
"report": "impression: 1. Short interval development of massive cardiomegaly with globular\n configuration, concerning for pericardial effusion.\n \n 2. Trace left effusion with plate-like atelectasis. Possible trace right\n effusion, unchanged. \n \n Findings reported to Dr. ___ by phone at 4 a.m. on ___. Findings: Frontal and lateral views of the chest demonstrate left pectoral\n single lead AICD with stable position of lead terminating in the right\n ventricle. The heart appears globular and enlarged, more pronounced as\n compared to ___, morphology suggestive of pericardial effusion. \n There is plate-like atelectasis in the left base with associated pleural\n effusion, which is decreased since preceding exam. There is no pneumothorax\n or frank edema. Mild blunting of the right costophrenic angle is unchanged.",
"image_path": [
"p11/p11607628/s52356321/9c44b35d-68d09c0c-3cfbce66-0341de07-1c0346ee.jpg"
],
"split": "test"
},
{
"id": "38b3b47d-6984aed6-acb1ea60-2c93049b-1ccdfc91",
"study_id": 57339166,
"subject_id": 15840907,
"report": "Compared to ___ there is increased opacification within the right lower\n lobe with silhouetting of the right hemidiaphragm. This may represent right\n lower lobe atelectasis, however infectious process or asymmetric edema cannot\n be excluded. Additional areas of opacification in the right upper lung may\n represent asymmetric pulmonary edema. Cardiac silhouette is enlarged likely\n representing volume overload. A PA and lateral chest radiograph may be\n obtained to help localize area of consolidation. A Chest CT with contrast\n should be obtained once the patient is more stable to rule out presence of\n underlying mass. Findings were discussed with Dr. ___ is at 16:48 on ___ via telephone.",
"image_path": [
"p15/p15840907/s57339166/38b3b47d-6984aed6-acb1ea60-2c93049b-1ccdfc91.jpg"
],
"split": "test"
},
{
"id": "28c17b79-14a8e7a1-14591313-2a68d678-39106288",
"study_id": 57873452,
"subject_id": 10268877,
"report": "As compared to the previous radiograph, the monitoring and support\n devices are constant in position.\n \n The pre-existing right basal opacity, with maximum in the infrahilar area, is\n not substantially changed. On the left, there is decreased visibility of the\n left hemidiaphragm, suggesting the appearance of either atelectasis or small\n left pleural effusion. Unchanged moderate cardiomegaly. The right\n costophrenic sinus is unremarkable.",
"image_path": [
"p10/p10268877/s57873452/28c17b79-14a8e7a1-14591313-2a68d678-39106288.jpg"
],
"split": "test"
},
{
"id": "2d93fd96-9b0fecad-1fdab811-37caf33a-3874a948",
"study_id": 57424140,
"subject_id": 16826047,
"report": "impression: 1. Increased moderate right loculated pleural effusion. Unchanged\n positioning of a right pleural catheter.\n \n 2. Slight increase in right mid to lower lung heterogeneous opacities, likely\n partially due to increased pleural fluid, although atelectasis or infection in\n this region is certainly possible.\n \n 3. Borderline pulmonary edema.\n \n 4. Unchanged mild cardiomegaly.\n \n 5. Increased central adenopathy compared to prior radiographs from ___. Further evaluation could be performed with CT, if clinically\n indicated.\n \n Findings and recommendations were discussed with Dr. ___ by Dr. ___\n at 8:58 a.m. via telephone on the day of the study. Findings: There is redemonstration of a right pleural catheter, with its tip\n projecting over the posterior pleural space. A moderate loculated right\n pleural effusion is slightly increased in size compared to the most recent\n radiograph from ___. Heterogeneous opacities in the right mid to\n lower lung are slightly increased, possibly partially due to overlying pleural\n fluid, although atelectasis or infection in this region is certainly possible.\n There is borderline pulmonary edema. Mild cardiomegaly is not significantly\n changed. There is no definite left pleural effusion. No pneumothorax is\n seen. There is evidence of central adenopathy, increased compared to prior\n radiographs from ___.",
"image_path": [
"p16/p16826047/s57424140/2d93fd96-9b0fecad-1fdab811-37caf33a-3874a948.jpg"
],
"split": "test"
},
{
"id": "9a046e7c-057d79d3-d97632b4-19afc34b-e0beff6a",
"study_id": 54949810,
"subject_id": 17704774,
"report": "Comparison is made to previous study from ___.\n \n There are again seen diffuse masses and nodules throughout both lungs\n consistent with known widespread metastatic disease. There is a right-sided\n chest tube with distal tip at the right apex. The size of the pneumothorax at\n the right base, right lower chest wall, and right lung apex is unchanged. \n There is a persistent left retrocardiac opacity and left-sided pleural\n effusion. Hardware within the thoracic spine is again visualized.",
"image_path": [
"p17/p17704774/s54949810/9a046e7c-057d79d3-d97632b4-19afc34b-e0beff6a.jpg"
],
"split": "test"
},
{
"id": "41015709-991752ad-b8bf5519-0dd588fd-dec4d029",
"study_id": 58495629,
"subject_id": 19757720,
"report": "As compared to the previous radiograph, there is no relevant\n change. Near complete opacification of the right lung with multiple air\n bronchograms that has neither increased nor decreased in the interval. \n Unchanged widespread but less severe opacities on the left. Unchanged\n monitoring and support devices. No newly appeared parenchymal opacities. The\n regions of the costophrenic sinuses are not included on the image.",
"image_path": [
"p19/p19757720/s58495629/41015709-991752ad-b8bf5519-0dd588fd-dec4d029.jpg"
],
"split": "test"
},
{
"id": "0ae07ada-41d03c2a-ec74ae48-d0c17cec-343ae6fa",
"study_id": 50126222,
"subject_id": 11022245,
"report": "impression: Slight improvement in mild pulmonary edema. Patchy opacities in the lung\n bases may reflect atelectasis, but infection particularly in the left lung\n base cannot be completely excluded. Findings: Right-sided Port-A-Cath tip terminates at the junction of the SVC and right\n atrium. Patient is status post median sternotomy and aortic valve\n replacement. Lung volumes are low with mild enlargement of the cardiac\n silhouette, unchanged. Mediastinal and hilar contours are similar. There is\n mild pulmonary edema, slightly improved in the interval. Patchy opacities in\n the lung bases may reflect areas of atelectasis, but infection particularly in\n the left lung base cannot be completely excluded. No pleural effusion or\n pneumothorax is demonstrated. Elevation of the left hemidiaphragm is again\n noted. No acute osseous abnormality is visualized.",
"image_path": [
"p11/p11022245/s50126222/0ae07ada-41d03c2a-ec74ae48-d0c17cec-343ae6fa.jpg"
],
"split": "test"
},
{
"id": "ba021d0f-a80b547a-f46e1b2b-5b0a8ce9-3507868f",
"study_id": 59144799,
"subject_id": 18224196,
"report": "impression: Feeding tube tip in the distal stomach.\n Worsened pulmonary findings Findings: Feeding tube tip in the distal stomach. Central line, endotracheal tube have\n been removed. Sternotomy, valve replacements. Small bilateral pleural\n effusions have worsened. Left basilar atelectasis or infiltrate, worsened. \n Right basilar atelectasis, worsened. Increased heart size, more prominent. \n Mildly prominent pulmonary vascularity.",
"image_path": [
"p18/p18224196/s59144799/ba021d0f-a80b547a-f46e1b2b-5b0a8ce9-3507868f.jpg"
],
"split": "test"
},
{
"id": "6fa0dab9-9c76b1c5-e420ee1c-d851a556-a50a5a88",
"study_id": 56018459,
"subject_id": 18088200,
"report": "impression: 1. Left mid to lower lung atelectasis. Low lung volumes.\n 2. The patient is status post sternotomy with fracture of at least the first\n and second sternotomy wires and possibly the lower most sternotomy wire. Findings: Frontal and lateral views of the chest were obtained. The patient\n is status first median sternotomy. Again, there is fracture of at least the\n first and second sternal wires, the upper wire was seen to be fractured on the\n prior study, although the second wire was not clearly fractured at that time. \n There is left base atelectasis. No definite focal consolidation is seen. \n There are low lung volumes, which accentuate the bronchovascular markings. \n There is minimal blunting of the right costophrenic angle, although no\n definite pleural effusion is seen on the lateral view. There is no\n pneumothorax.\n \n The cardiac and mediastinal silhouettes are stable.",
"image_path": [
"p18/p18088200/s56018459/6fa0dab9-9c76b1c5-e420ee1c-d851a556-a50a5a88.jpg"
],
"split": "test"
},
{
"id": "1f37fa7f-bbfdda2f-9ae5bac4-0027124f-f462fe0b",
"study_id": 57334765,
"subject_id": 16435402,
"report": "impression: Vague opacity residua in the left mid to lower lung likely\n represents scarring in this patient with history of pneumonia in this region. \n No acute findings. Findings: There is unchanged opacity in the left mid lung which likely\n represents residual scarring in this patient with prior pneumonia in this\n region. Nipple shadows are noted bilaterally. No definite signs of acute\n consolidation, effusion or pneumothorax. No signs of pulmonary edema. The\n heart size and mediastinal contour are unremarkable. The bony structures are\n intact.",
"image_path": [
"p16/p16435402/s57334765/1f37fa7f-bbfdda2f-9ae5bac4-0027124f-f462fe0b.jpg"
],
"split": "test"
},
{
"id": "225164ad-9f7e5e4f-b9c9e387-2b07cdd5-10488e8b",
"study_id": 52624179,
"subject_id": 10933609,
"report": "impression: No acute cardiopulmonary process. Stable fibrotic changes in the\n upper lungs. Findings: PA and lateral images of the chest. The lungs well expanded. \n Bilateral upper lobe opacities consistent with chronic fibrosis are again\n seen, unchanged from prior exam. The lungs are otherwise clear. There is no\n pleural effusion or pneumothorax. The cardiomediastinal silhouette is\n unremarkable.",
"image_path": [
"p10/p10933609/s52624179/225164ad-9f7e5e4f-b9c9e387-2b07cdd5-10488e8b.jpg"
],
"split": "test"
},
{
"id": "04e9517d-42048357-acb498cb-3abdd733-bd007f09",
"study_id": 52578479,
"subject_id": 17340686,
"report": "impression: 1. No acute cardiopulmonary process.\n 2. Stable diffuse interstitial abnormality, moderate cardiomegaly, vascular\n engorgement and secondary signs of pulmonary hypertension. Findings: There is a diffuse mild interstitial abnormality, unchanged from\n prior chest radiographs, and likely chronic. There is no evidence of\n consolidation or edema. There is no pleural effusion or pneumothorax. There\n is evidence of stable pulmonary hypertension and vascular engorgement. The\n aorta is calcified and tortuous. The mediastinal contours are otherwise\n normal. The heart is moderately enlarged. A left Port-A-Cath is present with\n the tip in the right atrium.",
"image_path": [
"p17/p17340686/s52578479/04e9517d-42048357-acb498cb-3abdd733-bd007f09.jpg"
],
"split": "test"
},
{
"id": "02b1b4da-2bcf091c-b126afb0-da48d861-8ffa17a3",
"study_id": 51148398,
"subject_id": 19182863,
"report": "As compared to the previous radiograph, there is unchanged\n alignment of the sternal wires. The valvular replacement is unchanged. \n Unchanged lung volumes with, however, improved transparency at the lung bases\n and reduction in extent of the pre-existing interstitial opacities. In the\n lung apices however, signs of minimal basal apical blood flow redistribution\n remain present. Unchanged borderline size of the cardiac silhouette.\n \n Minimal dorsal pleural effusions, seen on the lateral radiograph only.",
"image_path": [
"p19/p19182863/s51148398/02b1b4da-2bcf091c-b126afb0-da48d861-8ffa17a3.jpg"
],
"split": "test"
},
{
"id": "2499c15e-4605f752-e137e424-4474ef69-839ebbaa",
"study_id": 56129930,
"subject_id": 11052935,
"report": "impression: Left lower lobe pneumonia, more apparent than on ___. Findings: There is increased opacification in the left lung base with\n obscuration of the left hemidiaphragm when compared to ___. Again noted\n is hyperinflation and flattening of the diaphragms suggesting emphysema. The\n cardiomediastinal silhouette is within normal limits.",
"image_path": [
"p11/p11052935/s56129930/2499c15e-4605f752-e137e424-4474ef69-839ebbaa.jpg"
],
"split": "test"
},
{
"id": "8aeadf93-9670a6fd-2e65b3ce-0719a2c7-d178e34c",
"study_id": 51070813,
"subject_id": 14177219,
"report": "impression: No pneumonia Findings: Interval decrease in the size of the cardiac silhouette which is now normal.\n Stable enlargement of the bilateral hila. Relative lucency of the left lower\n lobe is likely related to overlying soft tissue. No focal consolidation,\n pleural effusion or pneumothorax.",
"image_path": [
"p14/p14177219/s51070813/8aeadf93-9670a6fd-2e65b3ce-0719a2c7-d178e34c.jpg"
],
"split": "test"
},
{
"id": "ae716843-fde7cd99-a5fb83a1-9d5eb9d9-ffb02e30",
"study_id": 59287720,
"subject_id": 15378103,
"report": "In comparison with the study of ___, the monitoring and support\n devices remain in place. Diffuse bilateral pulmonary opacifications are\n essentially unchanged.",
"image_path": [
"p15/p15378103/s59287720/ae716843-fde7cd99-a5fb83a1-9d5eb9d9-ffb02e30.jpg"
],
"split": "test"
},
{
"id": "d72a1a8e-82ff68d3-b7f92ce9-a36fbe0c-1fd32274",
"study_id": 51244125,
"subject_id": 11512104,
"report": "impression: 1. Mild interstitial pulmonary edema. No focal consolidation.\n \n 2. Moderate cardiomegaly, not significantly changed.\n \n 3. Unchanged small left pleural effusion. Findings: Frontal and lateral radiographs of the chest were acquired. There\n is a diffuse interstitial abnormality, with a perihilar predominance,\n suggestive of mild interstitial pulmonary edema. Moderate enlargement of the\n cardiac silhouette is not significantly changed. A small left pleural\n effusion is not significantly changed. There is no definite right pleural\n effusion. The mediastinal contours are unchanged. There is a small hiatal\n hernia, not significantly changed. There is no pneumothorax. Surgical clips\n project over the upper abdomen on the lateral radiograph. Multilevel\n degenerative changes of the thoracolumbar spine are noted. Anterior wedging\n of a lower thoracic vertebral body is not significantly changed.",
"image_path": [
"p11/p11512104/s51244125/d72a1a8e-82ff68d3-b7f92ce9-a36fbe0c-1fd32274.jpg"
],
"split": "test"
},
{
"id": "42493196-32cde3ff-b94d0ab0-baf74d8e-a88ad016",
"study_id": 58198532,
"subject_id": 13475033,
"report": "impression: Chronic interstitial lung disease. No evidence of acute pulmonary edema. Findings: The lungs well expanded. Coarse reticular interstitial opacities are again\n noted bilaterally, consistent with chronic interstitial lung disease. No\n evidence acute pulmonary edema. There is no pleural effusion or pneumothorax.\n The cardiomediastinal silhouette is top-normal in size. Unchanged tortuous\n aorta",
"image_path": [
"p13/p13475033/s58198532/42493196-32cde3ff-b94d0ab0-baf74d8e-a88ad016.jpg"
],
"split": "test"
},
{
"id": "a0578edb-12a640ca-1ddab351-089c4d4c-00bb6f19",
"study_id": 54265960,
"subject_id": 18615099,
"report": "impression: Mild pulmonary vascular congestion, improved when compared to the\n prior exam. Findings: Patient is status post median sternotomy\n and CABG. Left-sided pacemaker device is noted with leads terminating in the\n right atrium and right ventricle, unchanged. The heart remains mildly\n enlarged but stable. The aorta is unfolded. There is mild pulmonary vascular\n congestion, which is improved when compared to the prior exam. No new focal\n consolidation, pleural effusion or pneumothorax is present. There are mild\n degenerative changes in the thoracic spine.",
"image_path": [
"p18/p18615099/s54265960/a0578edb-12a640ca-1ddab351-089c4d4c-00bb6f19.jpg"
],
"split": "test"
},
{
"id": "96970f3a-0571b454-3baba4d3-45236f65-abf7a9c6",
"study_id": 57420525,
"subject_id": 17257913,
"report": "impression: Stable chest findings, no evidence of pulmonary congestion or\n acute parenchymal infiltrates in this patient with history of cough. Findings: PA and lateral chest views were obtained with patient in upright\n position. Analysis is performed in direct comparison with the next preceding\n chest examination of ___. Heart size is normal. Relatively\n wide mediastinal and cardiac contours are compatible with previously on CT\n documented mediastinal lipomatosis. Accessible aortic contours are\n unremarkable. The pulmonary vasculature is not congested. No signs of acute\n or chronic parenchymal infiltrates are present and the lateral and posterior\n pleural sinuses are free. Skeletal structures of the thorax grossly\n unremarkable. In comparison with the next preceding study, no significant\n interval change can be identified. Prominence of soft tissue structures\n surrounding the skeletal structures of the thorax are indicative of rather\n advanced adiposity.",
"image_path": [
"p17/p17257913/s57420525/96970f3a-0571b454-3baba4d3-45236f65-abf7a9c6.jpg"
],
"split": "test"
},
{
"id": "1a329778-20bfaa24-80dfc02f-7f896fba-39d0dd88",
"study_id": 53546263,
"subject_id": 13606683,
"report": "impression: 1. Congestive heart failure with interstitial edema and small pleural\n effusions.\n \n 2. Hyperinflated lungs, in keeping with known emphysema on prior CT chest of\n ___. Findings: ICD with biventricular pacing lead remains in place. Stable\n cardiomegaly accompanied by pulmonary vascular congestion and new interstitial\n edema, superimposed upon chronic areas of linear scar in the mid and lower\n lungs. Lungs are overinflated, suggestive of COPD. Small pleural effusions\n are present bilaterally. Bones are diffusely demineralized.",
"image_path": [
"p13/p13606683/s53546263/1a329778-20bfaa24-80dfc02f-7f896fba-39d0dd88.jpg"
],
"split": "test"
},
{
"id": "954f63ab-17009b0a-74507f85-db57e82e-94a1eed1",
"study_id": 59142109,
"subject_id": 16622813,
"report": "Cardiomediastinal contours are stable in appearance. Lungs remain\n hyperinflated. A subtle area of increased opacity has developed at the left\n lung base and could reflect acute aspiration, developing pneumonia, or\n atelectasis. Other findings (including postoperative appearance of the right\n hemithorax and enlarged hilar structures due to a combination of enlarged\n pulmonary arteries and right hilar lymphadenopathy) appear unchanged since the\n recent chest radiograph.",
"image_path": [
"p16/p16622813/s59142109/954f63ab-17009b0a-74507f85-db57e82e-94a1eed1.jpg"
],
"split": "test"
},
{
"id": "8b21e141-af653815-b3918024-c96d4b9e-6805e677",
"study_id": 56805129,
"subject_id": 11293517,
"report": "impression: 1. Acute exacerbation of recurrent CHF. Possible right lower lobe pneumonia\n in the . Findings: Frontal and lateral views of the chest demonstrate new pulmonary\n and mediastinal vascular congestion, perihilar haziness and chronic moderate\n cardiomegaly. New right infrahilar consolidation could be regional edema or\n concurrent pneumonia. The leads of an atriobiventricular ICD are unchanged in\n position, as are two additional right sided right ventricular leads which\n cross the chest wall from right to the left pectoral pacemaker. There is no\n pleural effusion, or pneumothorax.",
"image_path": [
"p11/p11293517/s56805129/8b21e141-af653815-b3918024-c96d4b9e-6805e677.jpg"
],
"split": "test"
},
{
"id": "fd6d0847-90e245d6-5e8b9257-3f6a857c-cc3dccc6",
"study_id": 54830140,
"subject_id": 13475033,
"report": "impression: Mild cardiomegaly and mild interstitial edema. Findings: PA and lateral views of the chest were provided. The heart remains\n mildly enlarged. There is mild interstitial pulmonary edema which is similar\n to prior exam. No large effusion is seen. Eventration of the right\n hemidiaphragm is noted. Mediastinal contour is stable. No focal\n consolidation suggestive of pneumonia. The bony structures appear intact. No\n free air below the right hemidiaphragm. Aortic calcifications are again\n noted.",
"image_path": [
"p13/p13475033/s54830140/fd6d0847-90e245d6-5e8b9257-3f6a857c-cc3dccc6.jpg"
],
"split": "test"
},
{
"id": "1942d8aa-bc12ddf0-57ea2c73-ec049fab-e766a8bd",
"study_id": 51131475,
"subject_id": 18338007,
"report": "As compared to the previous radiograph, there is unchanged\n elevation of the left hemidiaphragm with subsequent decrease in volume of the\n left hemithorax. Otherwise, the lungs are more transparent than on the\n previous examination, likely to reflect improved ventilation. Unchanged mild\n subpleural scarring bilaterally, but no evidence of acute lung changes. No\n evidence of larger pleural effusions. No pneumothorax.",
"image_path": [
"p18/p18338007/s51131475/1942d8aa-bc12ddf0-57ea2c73-ec049fab-e766a8bd.jpg"
],
"split": "test"
},
{
"id": "7d620442-deb05a77-a0f55a7e-f9f1d0e1-99509e35",
"study_id": 58000887,
"subject_id": 14851532,
"report": "impression: Worsening moderate pulmonary edema as well as right moderate effusion.\n \n Left lower lobe parenchymal opacity in the superior segment is now obscured\n by increasing pulmonary edema. Findings: As compared to ___, interval worsening moderate pulmonary edema. \n Right moderate pleural effusion has also slightly increased. Small left\n effusion persists. Left lower lobe parenchymal opacity in the superior\n segment is now obscured by increasing pulmonary edema. Moderate cardiomegaly.\n No pneumothorax.",
"image_path": [
"p14/p14851532/s58000887/7d620442-deb05a77-a0f55a7e-f9f1d0e1-99509e35.jpg"
],
"split": "test"
},
{
"id": "8e161b87-cb333a65-3d63c0a2-06de571e-60c0978e",
"study_id": 55499739,
"subject_id": 19731864,
"report": "impression: No evidence of acute cardiopulmonary disease. Findings: The heart is moderately enlarged. The aortic arch is calcified. Again noted is\n mild prominence of the main pulmonary artery contour in the aortopulmonary\n window. There is no pleural effusion or pneumothorax. There is persistent\n minor atelectasis at the left lung base, but otherwise, the lungs appear\n clear.",
"image_path": [
"p19/p19731864/s55499739/8e161b87-cb333a65-3d63c0a2-06de571e-60c0978e.jpg"
],
"split": "test"
},
{
"id": "31fd8c2d-92304fd6-93dd126a-3ed4e346-c485de34",
"study_id": 53292802,
"subject_id": 14556809,
"report": "impression: Mild central pulmonar vascular engorgement. Findings: No focal consolidation, pleural effusion, or pneumothorax is\n detected. Heart and mediastinal contours are unchanged compared to prior with\n mild central pulmonary vascular engorgement. Elevation of the right\n hemidiaphragm is again noted. Single-lead pacer is seen in similar position.",
"image_path": [
"p14/p14556809/s53292802/31fd8c2d-92304fd6-93dd126a-3ed4e346-c485de34.jpg"
],
"split": "test"
},
{
"id": "8f27588d-1bdebd8f-27072fe7-d51a60d5-c6968fcf",
"study_id": 55652987,
"subject_id": 19720782,
"report": "impression: Persistent right-sided effusion and pulmonary vascular\n congestion. Findings: Single portable view of the chest. There is persistent elevation\n of the right hemidiaphragm with a superimposed right basilar opacity\n suggestive of an effusion, similar in size when compared to prior. There is\n also pulmonary vascular congestion, increased compared to prior. There is no\n definite focal consolidation. Cardiomediastinal silhouette is unchanged. \n Elevation of the right hilum with increased density in the right paratracheal\n region compatible with prior post-treatment changes, better characterized on\n prior CT.",
"image_path": [
"p19/p19720782/s55652987/8f27588d-1bdebd8f-27072fe7-d51a60d5-c6968fcf.jpg"
],
"split": "test"
},
{
"id": "71bfff81-56c6477b-3432d360-6d1f41d2-8b2d7988",
"study_id": 57663243,
"subject_id": 16855430,
"report": "impression: Pulmonary edema, small bilateral pleural effusions, mild\n cardiomegaly. Findings: Frontal and lateral views of the chest were obtained. Bilateral\n pleural effusions are seen as well as persistent pulmonary edema. Stable mild\n cardiomegaly noted. No interval changes are seen.",
"image_path": [
"p16/p16855430/s57663243/71bfff81-56c6477b-3432d360-6d1f41d2-8b2d7988.jpg"
],
"split": "test"
},
{
"id": "77961fbc-766a38fd-e7b726ed-43313009-06ed55d4",
"study_id": 55878458,
"subject_id": 10715477,
"report": "New PICC line on the right is projecting with its tip somewhere in\n the mediastinum. Appears to cross the midline, there is concern for potential\n arterial location. The initial line concerns were communicated over the\n telephone at the time of the wet read. Repeat PA and lateral radiograph,\n taken approximately an hour after the radiograph demonstrated the PICC line in\n the mid SVC. Potential small right pleural effusion. Stable moderate\n cardiomegaly.",
"image_path": [
"p10/p10715477/s55878458/77961fbc-766a38fd-e7b726ed-43313009-06ed55d4.jpg"
],
"split": "test"
},
{
"id": "13abc428-9f713fce-3b977311-23dd2093-f8c0d743",
"study_id": 59762262,
"subject_id": 15131736,
"report": "impression: Chronic moderate cardiomegaly and probably pulmonary hypertension, unchanged\n in appearance when compared to prior examination dated ___. No\n overt pulmonary edema or pneumonia. Findings: AP upright and lateral radiographs of the chest demonstrate low lung volumes.\n When compared to radiograph dated ___, there has been little\n interval change. The cardiomediastinal and hilar contours remain unchanged,\n the heart moderately enlarged. Prominent vasculature and prominence of the\n hila is suggestive of pulmonary hypertension. Obscuration of the bilateral\n costophrenic angles is consistent with likely small bilateral pleural\n effusions versus atelectasis. No acute osseous abnormalities identified.",
"image_path": [
"p15/p15131736/s59762262/13abc428-9f713fce-3b977311-23dd2093-f8c0d743.jpg"
],
"split": "test"
},
{
"id": "45e31ec5-029d54e9-1acec167-663a1397-bccb2493",
"study_id": 56614076,
"subject_id": 12185775,
"report": "As compared to the previous radiograph, there is a minimal decrease\n in extent of a pre-existing small right pleural effusion. Interstitial\n markings, on the other hand, are slightly increased, potentially reflecting\n increased interstitial fluid contents.\n \n Unchanged ___ of the cardiac silhouette. Unchanged basal areas of\n atelectasis, unchanged right venous introduction sheath. Also unchanged are\n left lung calcified granulomas.\n \n Overall, the findings indicate a mild increase in pulmonary edema.",
"image_path": [
"p12/p12185775/s56614076/45e31ec5-029d54e9-1acec167-663a1397-bccb2493.jpg"
],
"split": "test"
},
{
"id": "b2cda6f3-388157df-c26cec82-28b37970-af315339",
"study_id": 54355585,
"subject_id": 15840907,
"report": "impression: No acute cardiopulmonary pathology. Findings: The cardiomediastinal and hilar contours\n are normal. The lungs are well expanded and clear, without focal\n consolidation, pleural effusion or pneumothorax. Mild degenerative changes\n are seen in the thoracic spine.",
"image_path": [
"p15/p15840907/s54355585/b2cda6f3-388157df-c26cec82-28b37970-af315339.jpg"
],
"split": "test"
},
{
"id": "4d570d20-1f80af86-1855ab56-6d99bc9a-cd105562",
"study_id": 58128416,
"subject_id": 19759491,
"report": "impression: Left-sided pacer device is stable in position. Left-sided central venous\n catheter is also stable in position. Enlarged cardiomediastinal silhouette is\n again seen. Patient is status post median sternotomy and cardiac valve\n replacement. There is mild pulmonary vascular congestion/interstitial edema\n and a small left pleural effusion. Trace right pleural effusion is difficult\n to exclude. Evidence of old left-sided rib fractures is seen. Findings: Left-sided pacer device is stable in position. Left-sided central venous\n catheter is also stable in position. Enlarged cardiomediastinal silhouette is\n again seen. Patient is status post median sternotomy and cardiac valve\n replacement. There is mild pulmonary vascular congestion/interstitial edema\n and a small left pleural effusion. Trace right pleural effusion is difficult\n to exclude. Evidence of old left-sided rib fractures is seen.",
"image_path": [
"p19/p19759491/s58128416/4d570d20-1f80af86-1855ab56-6d99bc9a-cd105562.jpg"
],
"split": "test"
},
{
"id": "dc00203a-4168ce8c-d79d47d2-eef8780b-d3fe037a",
"study_id": 56990167,
"subject_id": 11924226,
"report": "Heart size is normal. Lung fields are clear. The superior\n mediastinum appears slightly widened, but this may be projectional. Patient\n is mildly rotated. Followup films in four to six weeks' time are recommended\n to keep this area under observation. Because of varying degrees of rotation,\n comparison to the previous examination of ___ is difficult.",
"image_path": [
"p11/p11924226/s56990167/dc00203a-4168ce8c-d79d47d2-eef8780b-d3fe037a.jpg"
],
"split": "test"
},
{
"id": "49c67d34-b57aa84d-37146bc3-a1b0773c-ef5be03c",
"study_id": 57801123,
"subject_id": 18088200,
"report": "impression: No evidence of acute disease. Findings: The patient is status post sternotomy and probably coronary artery\n bypass graft surgery. The heart is mildly enlarged. The mediastinal and\n hilar contours appear unchanged, including a prominent left-sided epicardial\n fat pad. The lung volumes are low. Streaky lingular opacity suggesting minor\n atelectasis or scarring appears unchanged. Minimal blunting of the right\n costophrenic sulcus is more suggestive of similar slight atelectatic change,\n less likely persistent trace pleural effusion. There has been no significant\n change.",
"image_path": [
"p18/p18088200/s57801123/49c67d34-b57aa84d-37146bc3-a1b0773c-ef5be03c.jpg"
],
"split": "test"
},
{
"id": "f4ed24b7-7ce4f984-cadc1a40-43fde803-53ae7d9b",
"study_id": 59638609,
"subject_id": 14387068,
"report": "impression: OG tube coiled within the stomach with the tip pointing towards\n the fundus. Otherwise, no significant interval change.\n \n These findings were reported to Dr. ___ by Dr. ___ ___ telephone at\n 2:30pm Findings: There has been placement of an OG feeding tube which is coiled\n within the stomach with the tip pointing towards the fundus. Compared to the\n most recent prior radiograph, there has been no significant change. Moderate\n loculated right pleural effusion, is unchanged. Left mid and lower lung\n opacities are stable. There is no pneumothorax. Cardiac silhouette is\n enlarged but stable.",
"image_path": [
"p14/p14387068/s59638609/f4ed24b7-7ce4f984-cadc1a40-43fde803-53ae7d9b.jpg"
],
"split": "test"
},
{
"id": "f6a7a470-9e057a45-d244e0e5-3efe1422-bb946478",
"study_id": 58283482,
"subject_id": 19991135,
"report": "In comparison with the study of ___, one of the right chest tubes\n appears to have been removed. No definite pneumothorax is appreciated. \n Post-surgical changes persist in the right hemithorax and there is extensive\n subcutaneous gas along the right lateral chest wall.",
"image_path": [
"p19/p19991135/s58283482/f6a7a470-9e057a45-d244e0e5-3efe1422-bb946478.jpg"
],
"split": "test"
},
{
"id": "7f893546-338c10fd-6a9cd08f-10d75928-62b63ac6",
"study_id": 59375123,
"subject_id": 18767957,
"report": "impression: No acute cardiopulmonary process. Findings: The cardiomediastinal and hilar contours are stable. There is no\n pleural effusion or pneumothorax. The lungs are well expanded and clear. \n Pulmonary vasculature is within normal limits.",
"image_path": [
"p18/p18767957/s59375123/7f893546-338c10fd-6a9cd08f-10d75928-62b63ac6.jpg"
],
"split": "test"
},
{
"id": "7d705bf2-0c6a9344-d86b9381-311c9eb2-e4b1ab6c",
"study_id": 52356800,
"subject_id": 19182863,
"report": "impression: Interval increase in right pleural effusion with complete\n atelectasis of the right middle and lower lobes, raising concern for bronchial\n obstruction.\n \n The above findings were communicated to Dr. ___ by Dr. ___ ___\n telephone at 4:55pm, ___ min after discovery. Findings: PA and lateral views of the chest demonstrate interval increase in\n size of right pleural effusion, along with complete atelectasis of the right\n middle and lower lobes, raising concern for bronchial obstruction. The right\n upper lobe and left lung are grossly clear. The heart size is unchanged. \n Median sternotomy wires and post-surgical changes associated with aortic valve\n replacement are unchanged.",
"image_path": [
"p19/p19182863/s52356800/7d705bf2-0c6a9344-d86b9381-311c9eb2-e4b1ab6c.jpg"
],
"split": "test"
},
{
"id": "bffeb923-b2e49523-b66fa14c-e5d62eb0-93afffd1",
"study_id": 59721249,
"subject_id": 16043240,
"report": "impression: Persistent left lung base atelectasis. Otherwise, unremarkable. Findings: PA and lateral views of the chest are obtained. The previously\n noted right IJ central venous catheter has been removed. Midline sternotomy\n wires and mediastinal clips are stable. There is slight elevation of the left\n hemidiaphragm with left basilar atelectasis with overall improvement in left\n basilar aeration compared with prior study. The right lung is clear. Heart\n is top normal. Mediastinal contour is stable. Bony structures are intact. \n Right AC joint arthropathy is again noted. No free air below the right\n hemidiaphragm.",
"image_path": [
"p16/p16043240/s59721249/bffeb923-b2e49523-b66fa14c-e5d62eb0-93afffd1.jpg"
],
"split": "test"
},
{
"id": "8fd47aef-a0002ac5-00dd791e-784fc4a3-a7bc5026",
"study_id": 59918608,
"subject_id": 13475033,
"report": "impression: Unchanged prominent interstitial markings reflecting chronic lung\n disease with possible superimposed mild pulmonary vascular congestion,\n although not striking. Findings: There is no definite pleural\n effusion or pneumothorax. The enlarged cardiomediastinal silhouette with\n diffuse interstitial markings is unchanged from prior. As previously\n suggested, this may reflect chronic interstitial lung disease with\n superimposed pulmonary vascular congestion. A right-side central line\n terminates in the right atrium. Although the exam is limited by overlying\n trauma board, there is no displaced rib fracture.",
"image_path": [
"p13/p13475033/s59918608/8fd47aef-a0002ac5-00dd791e-784fc4a3-a7bc5026.jpg"
],
"split": "test"
},
{
"id": "c8b95c4e-1ab26289-9107ecb6-6e70a749-ec02c584",
"study_id": 51435164,
"subject_id": 16826047,
"report": "In comparison with study of ___, despite the right Pleurx catheter\n in place, there is still a substantial layering pleural effusion with\n compressive atelectasis at the right base. The left lung is essentially clear\n at this time.\n \n Continued enlargement of the cardiac silhouette with minimal if any vascular\n congestion. No acute focal pneumonia on the left.",
"image_path": [
"p16/p16826047/s51435164/c8b95c4e-1ab26289-9107ecb6-6e70a749-ec02c584.jpg"
],
"split": "test"
},
{
"id": "a194aa87-2cb7c882-7602c814-7712dbb4-9ac8dea7",
"study_id": 54973829,
"subject_id": 12074041,
"report": "impression: No evidence of acute disease. Findings: The heart is at the upper limits of normal size. Linear\n calcification projects over the right lung apex. The lungs appear otherwise\n clear. There are no pleural effusions or pneumothorax. Vascular\n calcifications are widespread. No free air is demonstrated. There are\n moderate to severe degenerative changes involving each glenohumeral joints.\n Mild degenerative changes are present along the visualized lower thoracic\n spine.",
"image_path": [
"p12/p12074041/s54973829/a194aa87-2cb7c882-7602c814-7712dbb4-9ac8dea7.jpg"
],
"split": "test"
},
{
"id": "06da0b0e-ad407abe-e199913d-e079da96-22a7c445",
"study_id": 54073075,
"subject_id": 13586204,
"report": "impression: 1. Continued improvement in pulmonary edema.\n 2. Moderate bilateral pleural effusions. Findings: Since the previous radiograph, there has been continued improvement\n in the previously described pulmonary edema. There are moderate bilateral\n effusions, which are unchanged. There are small bibasilar hazy opacities\n consistent with atelectasis. The cardiomediastinal silhouette is normal. \n Cervical hardware is again noted.",
"image_path": [
"p13/p13586204/s54073075/06da0b0e-ad407abe-e199913d-e079da96-22a7c445.jpg"
],
"split": "test"
},
{
"id": "8146d764-df8a61cc-05eee7e7-2a09b0ca-af854e29",
"study_id": 56619225,
"subject_id": 17147859,
"report": "impression: Limited, negative. Findings: AP upright and lateral views of the chest provided. Lung volumes are low with\n bibasilar atelectasis noted. Perihilar bronchovascular crowding is also\n noted. The heart is likely within normal limits of size. No large effusion\n or pneumothorax. No convincing signs of pneumonia. Bony structures are\n intact.",
"image_path": [
"p17/p17147859/s56619225/8146d764-df8a61cc-05eee7e7-2a09b0ca-af854e29.jpg"
],
"split": "test"
},
{
"id": "879a2872-4e21c290-5352ae99-8805af62-5adc6c28",
"study_id": 56290236,
"subject_id": 18767957,
"report": "impression: No acute intrathoracic process. CT is more sensitive for\n detection of mass lesions. Findings: This study was not made available for my interpretation until\n today, ___. Frontal and lateral views of the chest were obtained. \n Increased opacity at the right lung base is likely due to overlapping vascular\n structures. There is no focal consolidation, pleural effusion or\n pneumothorax. Heart size is top normal. Mediastinal silhouette and hilar\n contours are normal.",
"image_path": [
"p18/p18767957/s56290236/879a2872-4e21c290-5352ae99-8805af62-5adc6c28.jpg"
],
"split": "test"
},
{
"id": "79de3895-78f8039f-6010f064-7af8dd2e-e73deecb",
"study_id": 53414987,
"subject_id": 19389547,
"report": "As compared to the previous radiograph, the pre-existing partly\n pleural partly parenchymal opacities on the right have completely resolved. \n There is an obviously post-surgical rib defect on the right at the level of\n the fifth rib. Minimal scarring in the region of the middle lobe, but no\n acute changes. No pleural effusions. No pneumonia. Normal size of the\n cardiac silhouette.",
"image_path": [
"p19/p19389547/s53414987/79de3895-78f8039f-6010f064-7af8dd2e-e73deecb.jpg"
],
"split": "test"
},
{
"id": "ca198d4c-70be63ec-5974f3e9-d6320a38-4eb83158",
"study_id": 56969126,
"subject_id": 17770657,
"report": "impression: 1. Background COPD, with suspected pulmonary hypertension.\n 2. Status post sternotomy, with mediastinal clips. No CHF. \n 3. No acute infiltrate identified. Residual scarring noted, detailed above. \n 4. No pneumothorax detected. Findings: The lungs are hyperinflated and the diaphragms are flattened, consistent with\n COPD. Multiple surgical clips are seen about the mediastinum, consistent with\n prior surgery. A linear wire-like density is again noted in the retrosternal\n region, unchanged. Previously seen anterior chest wall drains have been\n removed. \n \n On today's exam, the heart is not enlarged. The aorta is unfolded. There is\n prominence of a hila suggesting element of pulmonary hypertension, probably\n unchanged. There is some linear atelectasis and/or scarring at both lung\n bases. Ring-like opacity in the left upper zone seen on the prior study has\n resolved, with only minimal residual scarring. No CHF or new focal infiltrate\n is detected. No effusions are identified. No pneumothorax is detected.\n Relative lucency at the right base is thought to represent an artifact due to\n overlying soft tissues of the chest.",
"image_path": [
"p17/p17770657/s56969126/ca198d4c-70be63ec-5974f3e9-d6320a38-4eb83158.jpg"
],
"split": "test"
},
{
"id": "e5d1a79a-101a6822-e589102f-05d0d1c7-fe74e5e5",
"study_id": 53276158,
"subject_id": 16848073,
"report": "impression: No pneumothorax, pneumomediastinum, or deep cervical air. \n Recommend repeat PA and lateral imaging later today to verify these findings. \n Otherwise unremarkable chest radiograph. \n \n These findings were communicated to Dr. ___ at 11:55 a.m. by telephone by\n Dr. ___. Findings: There is no pneumothorax, pneumomediastinum, or deep cervical air. \n Recommend repeat PA and lateral radiographs of the chest to verify these\n findings. The lungs are well expanded. There is no evidence of acute cardiac\n or pulmonary process. Cardiomediastinal silhouette is unremarkable.",
"image_path": [
"p16/p16848073/s53276158/e5d1a79a-101a6822-e589102f-05d0d1c7-fe74e5e5.jpg"
],
"split": "test"
},
{
"id": "2861b26c-2fa81175-590e2970-96ddb7e3-43145356",
"study_id": 55779414,
"subject_id": 14295224,
"report": "impression: Right mid lung opacity, waxing and waning since ___, compatible with recurrent pneumonia. Follow-up is recommended after\n therapy to exclude neoplasm given the patient's history of malignancy.\n \n Final impression was communicated via phone call to Dr. ___ by ___\n ___ on ___ at 12:45pm. Findings: Frontal and lateral views of the chest were obtained. The heart is\n of normal size with normal cardiomediastinal contours. The known gastric\n pull-through for esophageal cancer is not distended. Bony coalition between\n the posterior arch of the sixth and seventh right ribs is congenital. There\n is increased vague opacity in the right mid lung superimposed on the site of\n bony coalition. Opacity in this area is increased since ___ but is\n similar to ___, and may represent recurrent pneumonia. A right\n lower lobe nodule is similar in size through ___. No pleural\n effusion or pneumothorax is present. The pulmonary vasculature is\n unremarkable. No radiopaque foreign body.",
"image_path": [
"p14/p14295224/s55779414/2861b26c-2fa81175-590e2970-96ddb7e3-43145356.jpg"
],
"split": "test"
},
{
"id": "b5da9d38-5e0c570b-e88b17c1-029654a9-a4f8a0b3",
"study_id": 51966612,
"subject_id": 10402372,
"report": "impression: No acute cardiopulmonary process. No significant interval\n change. Please note that peribronchovascular ground-glass opacities at the\n left greater than right lung bases seen on the prior chest CT of ___\n were not appreciated on prior chest radiography on the same date and may still\n be present. Additionally, several pulmonary nodules measuring up to 3 mm are\n not not well appreciated on the current study-CT is more sensitive. Findings: Frontal and lateral views of the chest are obtained. The lungs\n remain hyperinflated, suggesting chronic obstructive pulmonary disease. No\n focal consolidation, pleural effusion, or evidence of pneumothorax is seen. \n The cardiac and mediastinal silhouettes are stable and unremarkable. Hilar\n contours are also stable.",
"image_path": [
"p10/p10402372/s51966612/b5da9d38-5e0c570b-e88b17c1-029654a9-a4f8a0b3.jpg"
],
"split": "test"
},
{
"id": "5f4fdb1c-97aed97d-fa4a3b1b-9da4ea33-e9df38ee",
"study_id": 55430187,
"subject_id": 16043637,
"report": "impression: No acute cardiopulmonary process. Findings: The heart size is unchanged in size, and a left cardiac pacer device is in\n stable position with its lead in appropriate position. The patient is status\n post aortic valve replacement and median sternotomy. The lungs are clear of\n focal consolidation, pleural effusion or overt pulmonary edema. A right PICC\n terminates in the lower SVC.",
"image_path": [
"p16/p16043637/s55430187/5f4fdb1c-97aed97d-fa4a3b1b-9da4ea33-e9df38ee.jpg"
],
"split": "test"
},
{
"id": "02459e00-c32b7e61-1d7eaf5a-b10fc8f6-063f7d90",
"study_id": 57929429,
"subject_id": 16043637,
"report": "impression: 1. Expected normal position of permanent pacer electrodes.\n 2. Stable chest radiograph, no pneumothorax. Findings: A permanent pacer is again noted with leads terminating in the\n right atrium and right ventricle in satisfactory position. The metallic\n portion of an aortic valve prosthesis is again visualized. Sternotomy wires\n are also present. Heart size remains normal. The mediastinal and hilar\n contours are normal. There is no pleural effusion or pneumothorax. The lungs\n are clear.",
"image_path": [
"p16/p16043637/s57929429/02459e00-c32b7e61-1d7eaf5a-b10fc8f6-063f7d90.jpg"
],
"split": "test"
},
{
"id": "d8bc7ccc-a2bac7c8-1dd6d0a5-5ed27c66-4f556bac",
"study_id": 57363067,
"subject_id": 11934114,
"report": "impression: 1. Worsened now mild-to-moderate interstitial pulmonary edema and\n small-to-moderate bilateral layering pleural effusions.\n \n 2. Left-sided rib fractures in retrospect apparent since at least ___. Findings: There is interval worsening of now mild-to-moderate interstitial pulmonary\n edema and small-to-moderate bilateral layering pleural effusions. There is no\n evidence of pneumothorax. There is associated bibasilar atelectasis with no\n focal opacities concerning for pneumonia. The cardiomediastinal and hilar\n contours are stable demonstrating moderate cardiomegaly. Note is made of\n multiple left-sided rib fractures that in retrospect can be demonstrated on\n radiographs from ___.",
"image_path": [
"p11/p11934114/s57363067/d8bc7ccc-a2bac7c8-1dd6d0a5-5ed27c66-4f556bac.jpg"
],
"split": "test"
},
{
"id": "6aff92fc-a55af9c9-b11a0394-d2d62191-122cdf01",
"study_id": 50720959,
"subject_id": 11880923,
"report": "In comparison with the study of ___, there is slightly better\n inspiration. The left hemidiaphragm is not sharply seen and there is hazy\n opacification at the left base. This suggests a possible atelectasis and\n effusion. \n \n Monitoring and support devices are unchanged.",
"image_path": [
"p11/p11880923/s50720959/6aff92fc-a55af9c9-b11a0394-d2d62191-122cdf01.jpg"
],
"split": "test"
},
{
"id": "5df8c586-2f6adf15-722e6f13-ffa8a117-acd92b9a",
"study_id": 50205123,
"subject_id": 10933609,
"report": "impression: Chronic fibrotic changes within both lung apices. Low lung volumes with\n probable bibasilar atelectasis, though infection or aspiration cannot be\n excluded. Small left pleural effusion. Known left 11th rib fracture is not\n clearly seen on the current exam. Findings: The heart size is normal. Lung volumes are low. Biapical fibrotic changes\n with traction bronchiectasis is re- demonstrated. Minimal blunting of the\n left costophrenic angle suggests a trace left pleural effusion. Streaky\n bibasilar airspace opacities likely reflect atelectasis. No pneumothorax is\n identified. Known fracture of the left 11th rib is not clearly delineated on\n this exam. Clips are seen projecting over the left upper quadrant. No new\n fractures are seen. There is crowding of the bronchovascular structures but\n no overt pulmonary edema is demonstrated.",
"image_path": [
"p10/p10933609/s50205123/5df8c586-2f6adf15-722e6f13-ffa8a117-acd92b9a.jpg"
],
"split": "test"
},
{
"id": "14ff31ea-afb9a3f3-fca0fe57-1fb4e5d4-9f537945",
"study_id": 55430988,
"subject_id": 10268877,
"report": "As compared to the previous radiograph, there is no relevant\n change. Monitoring and support devices are constant. Constant cardiomegaly\n with relatively extensive retrocardiac atelectasis and the potential presence\n of a small left pleural effusion. Mild pulmonary edema. Areas of atelectasis\n at the right lung base. No newly occurred parenchymal opacities. No\n pneumothorax.",
"image_path": [
"p10/p10268877/s55430988/14ff31ea-afb9a3f3-fca0fe57-1fb4e5d4-9f537945.jpg"
],
"split": "test"
},
{
"id": "5ad83d61-44f64350-e0fe61c9-c78a0842-626ecb1f",
"study_id": 59691119,
"subject_id": 19759491,
"report": "In comparison with the study of ___, there is still enlargement\n of the cardiac silhouette with some elevation of pulmonary venous pressure,\n though substantially less than on the prior study. The more focal\n opacification at the left base is not appreciated at this time. There is\n fluid within one of the major fissures, though no substantial free pleural\n effusion.",
"image_path": [
"p19/p19759491/s59691119/5ad83d61-44f64350-e0fe61c9-c78a0842-626ecb1f.jpg"
],
"split": "test"
},
{
"id": "2d1e6273-8e13a27a-10e404d2-b5ff44ae-03ad30ce",
"study_id": 57231469,
"subject_id": 16508811,
"report": "In comparison with the study of ___, there is continued\n enlargement of the cardiac silhouette with congestive failure. Poor\n definition of the hemidiaphragms is consistent with bilateral pleural effusion\n and compressive atelectasis.\n \n There is an area of more coalescent opacification in the right upper zone that\n is asymmetric with the opposite side. In the appropriate clinical setting,\n this could well represent a developing focus of pneumonia.",
"image_path": [
"p16/p16508811/s57231469/2d1e6273-8e13a27a-10e404d2-b5ff44ae-03ad30ce.jpg"
],
"split": "test"
},
{
"id": "2c2536da-bc7670f1-2bbb98a2-e03017cc-87c616ee",
"study_id": 52110747,
"subject_id": 14556809,
"report": "As compared to the previous radiograph, the patient has been\n intubated. The tip of the endotracheal tube projects 3 cm above the carina. \n A left pectoral pacemaker is in unchanged position.\n \n In the interval, lung volumes have substantially decreased, there are signs\n indicative of mild-to-moderate pulmonary edema and atelectasis at both lung\n bases. No evidence of pneumonia. Short-term followup with chest radiographs\n is required.",
"image_path": [
"p14/p14556809/s52110747/2c2536da-bc7670f1-2bbb98a2-e03017cc-87c616ee.jpg"
],
"split": "test"
},
{
"id": "e539ba13-0f60a2b9-c5777304-ac5661fd-236f33a8",
"study_id": 55715754,
"subject_id": 15857729,
"report": "impression: Massive cardiomegaly with trace bilateral pleural effusions. \n Opacity within the right mid-to-lower lung is concerning for pneumonia. Findings: Semi-upright portable AP view of the chest provided. The heart is\n massively enlarged. There are trace pleural effusions. Increased opacity in\n the right mid-to-lower lung is concerning for pneumonia. The left lung\n appears essentially clear. No pneumothorax. The mediastinal contour appears\n normal. Bony structures are intact.",
"image_path": [
"p15/p15857729/s55715754/e539ba13-0f60a2b9-c5777304-ac5661fd-236f33a8.jpg"
],
"split": "test"
},
{
"id": "096b32ec-f7a979c1-df4bc2e0-589ac982-da947b3f",
"study_id": 50848467,
"subject_id": 16043637,
"report": "impression: Slight increased hazy opacities at the right lung base which may reflect\n developing consolidation in the appropriate clinical setting. Findings: There are slightly increased hazy opacities at the right lung base. The\n cardiomediastinal silhouette and hilar contours are unchanged. There is no\n pleural effusion or pneumothorax. Median sternotomy wires, left chest\n pacemaker, as well as cardiac valve replacement are unchanged.",
"image_path": [
"p16/p16043637/s50848467/096b32ec-f7a979c1-df4bc2e0-589ac982-da947b3f.jpg"
],
"split": "test"
},
{
"id": "e441d29c-c156066e-10c1c80f-419f440f-7a4bf94d",
"study_id": 55101140,
"subject_id": 11293517,
"report": "impression: Mild pulmonary congestion. Findings: Frontal and lateral views of the chest were obtained. Mild\n cardiomegaly is similar to prior. There is mild pulmonary congestion without\n overt pulmonary edema. No focal pulmonary consolidation, pleural effusion, or\n pneumothorax is seen. The osseous structures are unremarkable. The leads of\n an atriobiventricular ICD are in similar position to prior.",
"image_path": [
"p11/p11293517/s55101140/e441d29c-c156066e-10c1c80f-419f440f-7a4bf94d.jpg"
],
"split": "test"
},
{
"id": "c1b005c9-f5bb265e-ba26b793-e1767adb-b6c50b32",
"study_id": 57242265,
"subject_id": 13606683,
"report": "impression: Congestive heart failure with interstitial edema superimposed\n upon chronic changes of emphysema and pleural-parenchymal scarring. Findings: There has been previous median sternotomy and aortic valve\n replacement. ICD pacing device remains in place, with unchanged position of\n leads in the right atrium, right ventricle and an additional lead for\n biventricular pacing. Moderate cardiomegaly is stable in appearance, is\n accompanied by upper zone vascular redistribution and mild interstitial edema.\n The latter superimposed upon chronic pleural and parenchymal scarring within\n the mid and lower lungs bilaterally. Lung volumes are increased, in keeping\n with history of COPD. There are questionable small bilateral pleural\n effusions present.",
"image_path": [
"p13/p13606683/s57242265/c1b005c9-f5bb265e-ba26b793-e1767adb-b6c50b32.jpg"
],
"split": "test"
},
{
"id": "db56399e-4f04b226-d9773c85-a6d565a6-04fe3904",
"study_id": 58929701,
"subject_id": 12963531,
"report": "impression: 1. Area of increase density overlying the right hilum with a sharp lower\n margin is of unclear clinical significance. Chest CT is recommended for\n further assessment.\n 2. Severe cardiomegaly, unchanged.\n \n The impression was entered as an urgently flagged wet read on the ED dashboard\n by Dr ___ on ___ at 9:05 am after discussion with the attending as the\n patient was still in the ED. Findings: The lungs are well expanded and clear. Area of increase density\n overlying the right hilum with a sharp lower margin is of unclear clinical\n significance. Severe cardiomegaly is reidentified. The hilar contours are\n unremarkable. There is no pleural effusion or pneumothorax.",
"image_path": [
"p12/p12963531/s58929701/db56399e-4f04b226-d9773c85-a6d565a6-04fe3904.jpg"
],
"split": "test"
},
{
"id": "2d45a143-1df013b8-730bd381-c219de78-7ad22f77",
"study_id": 59044985,
"subject_id": 18110020,
"report": "Lungs are grossly clear. There are no new lung opacities which are\n of concern. There is no evidence to suggest pleural effusion or pneumothorax.\n Severe scoliosis is noted. Cardiomediastinal silhouette is unchanged. The\n nasogastric tube tip is in the stomach and right PICC line is approximately at\n the mid SVC.",
"image_path": [
"p18/p18110020/s59044985/2d45a143-1df013b8-730bd381-c219de78-7ad22f77.jpg"
],
"split": "test"
},
{
"id": "0f257273-0fa8c76f-737b4a98-eedda2aa-44d82e39",
"study_id": 54625738,
"subject_id": 19623993,
"report": "impression: No signs of pneumonia or other acute process. Findings: PA and lateral views of the chest were obtained demonstrating clear\n well expanded lungs without focal consolidation, effusion, pneumothorax. \n There is no free air below the right hemidiaphragm. Cardiomediastinal\n silhouette is normal. Bony structures are intact.",
"image_path": [
"p19/p19623993/s54625738/0f257273-0fa8c76f-737b4a98-eedda2aa-44d82e39.jpg"
],
"split": "test"
},
{
"id": "0fef51dc-8e713f62-0c7f23dc-fb145074-68b8ec4b",
"study_id": 51024049,
"subject_id": 17770657,
"report": "impression: Dobbhoff tube with tip coiled in stomach and tip terminating in\n the upper esophagus. Multiple opacifications likely represent multifocal\n pneumonia, possibly due to aspiration. Loculated pleural effusion in the\n right fissure. Findings: Portable chest radiograph demonstrates interval insertion of a\n Dobbhoff tube which is coiled within in the stomach and then turns back to\n terminate in the esophagus at the level of the clavicles. There is a\n left-sided PICC line with tip terminating in the mid SVC. There are\n multifocal opacifications, worst in the lung bases, which may represent\n atelectasis, though infectious process is consideration, possibly aspiration. \n Dense opacification projecting over the right mid lung corresponds to a\n loculated fissural effusion evident on the prior CT.",
"image_path": [
"p17/p17770657/s51024049/0fef51dc-8e713f62-0c7f23dc-fb145074-68b8ec4b.jpg"
],
"split": "test"
},
{
"id": "ab2de298-ded88235-d07642c2-25f1fa59-af01ed92",
"study_id": 54753684,
"subject_id": 13979643,
"report": "impression: Mild pulmonary vascular congestion. Subtle opacity in the right upper lung,\n possibly representing a confluence of shadows, but follow-up radiographs are\n recommended to assess for interval change. Findings: There is mild pulmonary vascular\n congestion. A subtle ill-defined opacity in the right upper lung may reflect\n overlapping shadows, though an underlying parenchymal process may be present. \n Follow-up radiographs are recommended to assess for interval change. Linear\n scarring within the right mid lung is unchanged from prior. Linear opacities\n within the bilateral lung bases likely reflect areas of subsegmental\n atelectasis. There is stable mild elevation of the left hemidiaphragm,\n unchanged from prior. The thoracic aorta is tortuous. Cardiomediastinal and\n hilar contours are within normal limits.",
"image_path": [
"p13/p13979643/s54753684/ab2de298-ded88235-d07642c2-25f1fa59-af01ed92.jpg"
],
"split": "test"
},
{
"id": "d506da5a-b2dad80c-f31e282e-15154de3-b4385bea",
"study_id": 55553875,
"subject_id": 12966004,
"report": "impression: Slight improvement of right upper lung opacity with increased\n bibasilar opacities possibly reflecting atelectasis or aspiration though\n worsening infection cannot be fully excluded. Findings: Endotracheal tube terminates 2.8 cm above the carina. Nasogastric\n tube terminates within the body of the stomach. Right internal jugular\n catheter ends in the lower SVC. Previously described right upper lung opacity\n is less conspicuous than on the prior. Bibasilar opacities are larger and\n could reflect atelectasis or an aspiration event. Worsening infection cannot\n be excluded. Small left pleural effusion is likely also present. The heart\n is normal in size, normal cardiomediastinal silhouette.",
"image_path": [
"p12/p12966004/s55553875/d506da5a-b2dad80c-f31e282e-15154de3-b4385bea.jpg"
],
"split": "test"
},
{
"id": "301ce3f6-a772d517-7d019547-b8f6d662-45d6850b",
"study_id": 59332553,
"subject_id": 14744884,
"report": "impression: No acute cardiopulmonary process. Findings: AP and lateral views of the chest. The lungs are clear of\n consolidation or effusion. The cardiac silhouette is enlarged but unchanged. \n No acute osseous abnormality is detected. Right brachiocephalic venous stent\n is again noted.",
"image_path": [
"p14/p14744884/s59332553/301ce3f6-a772d517-7d019547-b8f6d662-45d6850b.jpg"
],
"split": "test"
},
{
"id": "763d782b-5a51908c-3e57e293-836df343-de966853",
"study_id": 50943671,
"subject_id": 16848073,
"report": "impression: Right lower lobe opacity suggesting pneumonia or aspiration. Suspected\n moderate interstitial disease at the lung bases. Follow-up radiographs are\n recommended. Findings: A dual-lead pacemaker/ICD appears unchanged with leads terminating in the\n right atrium and ventricle, respectively. The heart is normal in size. There\n is increase in right infrahilar opacity probably correlating with focal right\n lower lobe opacity. This is superimposed on a probably more chronic\n interstitial abnormality at the lung bases, which is greater on the right than\n left. There is no definite pleural effusion or pneumothorax.",
"image_path": [
"p16/p16848073/s50943671/763d782b-5a51908c-3e57e293-836df343-de966853.jpg"
],
"split": "test"
},
{
"id": "7b1c0393-9d11556a-679af991-d0cc1d68-b1852b51",
"study_id": 54167884,
"subject_id": 19182863,
"report": "impression: Reappearance of moderate right pleural effusion. Findings: Reappearance of moderate right pleural effusion obscures the right heart\n border. There is elevation of the right hemidiaphragm. The cardiac\n silhouette continues to be mildly enlarged with no signs of vascular\n congestion. No focal consolidation is seen. Left internal jugular catheter\n ends in a known left persistent vena cava.",
"image_path": [
"p19/p19182863/s54167884/7b1c0393-9d11556a-679af991-d0cc1d68-b1852b51.jpg"
],
"split": "test"
},
{
"id": "f1096194-814152f3-c5c14405-305b19d8-0d4eaffb",
"study_id": 59999362,
"subject_id": 15518538,
"report": "impression: No acute cardiopulmonary process. Findings: The lungs are clear without focal consolidation. No pleural effusion or\n pneumothorax is seen. The cardiac and mediastinal silhouettes are\n unremarkable. The patient is status post median sternotomy with the superior\n most 2 sternotomy wires again seen to be fractured.",
"image_path": [
"p15/p15518538/s59999362/f1096194-814152f3-c5c14405-305b19d8-0d4eaffb.jpg"
],
"split": "test"
},
{
"id": "c826aa5d-6ff5ee3a-11a18fb2-ab264bed-566e1edb",
"study_id": 51988570,
"subject_id": 12074041,
"report": "impression: Minimal interstitial edema and mild cardiomegaly. Findings: Frontal and lateral views of the chest were obtained. A\n single-lead left-sided AICD is again seen with lead extending to the expected\n position of the right ventricle. There has been interval removal of a right\n internal jugular central venous catheter. There is minimal interstitial\n edema. No large pleural effusion or pneumothorax. The cardiac silhouette\n remains mildly enlarged. The aorta is tortuous. No focal consolidation seen.",
"image_path": [
"p12/p12074041/s51988570/c826aa5d-6ff5ee3a-11a18fb2-ab264bed-566e1edb.jpg"
],
"split": "test"
},
{
"id": "b800c916-3b94102e-b30f93af-af52c677-167e5233",
"study_id": 51584806,
"subject_id": 19800337,
"report": "impression: No acute cardiopulmonary process. Findings: PA and lateral views of the chest are compared to previous exam\n from ___. The lungs are now clear without focal consolidation or\n effusion. Cardiomediastinal silhouette is normal. Osseous and soft tissue\n structures are unremarkable.",
"image_path": [
"p19/p19800337/s51584806/b800c916-3b94102e-b30f93af-af52c677-167e5233.jpg"
],
"split": "test"
},
{
"id": "be022b6e-69a878a5-39db0aac-453cd12d-627ea0a0",
"study_id": 55187337,
"subject_id": 19759491,
"report": "impression: New left lower lobe infiltrate and effusion. Findings: Sternal wires, valve prosthesis, cardiac device, and mild cardiomegaly are\n unchanged. There is new left lower lobe infiltrate and small left effusion. \n There is also a small right effusion.",
"image_path": [
"p19/p19759491/s55187337/be022b6e-69a878a5-39db0aac-453cd12d-627ea0a0.jpg"
],
"split": "test"
},
{
"id": "61767c51-5b13fe95-8ee32eb0-6dc19ea8-be684efc",
"study_id": 52864337,
"subject_id": 13078497,
"report": "There has been interval intubation, with endotracheal tube tip\n terminating about 5 cm above the carina. Exam is otherwise remarkable for\n very slight improvement in widespread bilateral alveolar opacities,\n particularly when compared to the chest radiograph of ___. \n Bilateral pleural effusions are unchanged.",
"image_path": [
"p13/p13078497/s52864337/61767c51-5b13fe95-8ee32eb0-6dc19ea8-be684efc.jpg"
],
"split": "test"
},
{
"id": "21dd100a-bf76f673-4ee97c34-87797534-1ff8583e",
"study_id": 57833493,
"subject_id": 16662264,
"report": "impression: Unchanged bilateral pneumonia with decreased pleural effusions. Findings: Study is essentially unchanged from immediately prior study dated\n ___. Middle lobe and lingular infiltrate are once again observed and\n essentially unchanged. There has been a slight interval decrease of bilateral\n pleural effusions. No new areas of consolidation are appreciated. No\n pneumothorax. The cardiomediastinal silhouette is stable and within normal\n limits.",
"image_path": [
"p16/p16662264/s57833493/21dd100a-bf76f673-4ee97c34-87797534-1ff8583e.jpg"
],
"split": "test"
},
{
"id": "56800e51-37c27e17-e57356ac-463bc851-663bdfa9",
"study_id": 56970093,
"subject_id": 19061282,
"report": "impression: No acute cardiopulmonary process. Findings: Vascular stents are unchanged in position. No focal consolidation is seen. \n There is no large pleural effusion or pneumothorax. The cardiac and\n mediastinal silhouettes are stable. No pulmonary edema is seen.",
"image_path": [
"p19/p19061282/s56970093/56800e51-37c27e17-e57356ac-463bc851-663bdfa9.jpg"
],
"split": "test"
},
{
"id": "8e4f1e80-f399aae7-0d76204f-8cb99fb9-e837fe04",
"study_id": 54783326,
"subject_id": 13353878,
"report": "impression: No acute cardiopulmonary process. Findings: AP and lateral views of the chest. Right PICC is no longer visualized. The\n lungs are clear of consolidation or effusion. Cardiac silhouette is enlarged\n but stable. All left posterior 7th rib fracture is identified. \n Atherosclerotic calcifications noted at the aortic arch.",
"image_path": [
"p13/p13353878/s54783326/8e4f1e80-f399aae7-0d76204f-8cb99fb9-e837fe04.jpg"
],
"split": "test"
},
{
"id": "f5108618-8f9b67ff-661df382-f791f1ad-7a660047",
"study_id": 55696171,
"subject_id": 12736592,
"report": "Single portable view of the chest is compared to previous exam from\n earlier the same day at 4:57 p.m. There has been interval placement of a\n right-sided chest tube. Left-sided chest tube is again seen with some\n persistent left basilar pneumothorax. Cardiomediastinal silhouette is stable\n as are the osseous and soft tissue structures which are better characterized\n by CT scan.",
"image_path": [
"p12/p12736592/s55696171/f5108618-8f9b67ff-661df382-f791f1ad-7a660047.jpg"
],
"split": "test"
},
{
"id": "dd0edd5f-bbfc870a-23c7b603-2ee5bd53-caedb97b",
"study_id": 50149345,
"subject_id": 19757720,
"report": "As compared to the previous radiograph, there is no relevant\n change. Diffuse increased opacity of the right lung, with several air\n bronchograms. A pre-existing right pleural effusion seems to have moderately\n decreased. No changes in the left lung. Unchanged monitoring and support\n devices. Unchanged aspect of the cardiac silhouette.",
"image_path": [
"p19/p19757720/s50149345/dd0edd5f-bbfc870a-23c7b603-2ee5bd53-caedb97b.jpg"
],
"split": "test"
},
{
"id": "1e2bf7fd-0332021c-5954e527-9aef62e8-221c5e82",
"study_id": 56477444,
"subject_id": 12658295,
"report": "impression: Right lower lobe atelectasis with a small associated effusion,\n better assessed on concurrent CT. Findings: The lungs are well expanded and shows a right lower\n lobe opacity. The cardiac silhouette is enlarged. The mediastinal silhouette\n and hilar contours are normal. No pleural effusion or pneumothorax is\n present.",
"image_path": [
"p12/p12658295/s56477444/1e2bf7fd-0332021c-5954e527-9aef62e8-221c5e82.jpg"
],
"split": "test"
},
{
"id": "a65d3d93-ce43965b-d289b7d8-624367da-7d615da8",
"study_id": 59610928,
"subject_id": 16957952,
"report": "impression: Diffuse increased interstitial markings are compatible with\n minimal interstitial edema. No focal opacities concerning for pneumonia. Findings: There are increased interstitial markings bilaterally not\n significantly changed from ___, but no focal opacities. Heart size is\n top normal. The aorta is tortuous. There is no pleural effusion or\n pneumothorax. Sternotomy wires as well as mediastinal surgical clips from\n prior CABG are re-demonstrated and unchanged in position.",
"image_path": [
"p16/p16957952/s59610928/a65d3d93-ce43965b-d289b7d8-624367da-7d615da8.jpg"
],
"split": "test"
},
{
"id": "81045bbb-0ff47e0f-e6832f53-a8620841-66e813f0",
"study_id": 56632211,
"subject_id": 18828251,
"report": "In comparison with the study of ___, there is little overall\n change. Continued enlargement of the cardiac silhouette in a patient with\n intact midline sternal wires after CABG. No evidence of vascular congestion. \n The overall discordancy raises possibility of cardiomyopathy. Calcification\n is again seen in coronary vessels.\n \n No evidence of acute focal pneumonia.",
"image_path": [
"p18/p18828251/s56632211/81045bbb-0ff47e0f-e6832f53-a8620841-66e813f0.jpg"
],
"split": "test"
},
{
"id": "bb664e62-f26a58fb-f3f6515a-0cb91fa0-2638766f",
"study_id": 51150576,
"subject_id": 16319601,
"report": "impression: No pleural effusions bilaterally. Findings: Portable chest radiograph demonstrates unremarkable mediastinal,\n hilar, and cardiac contours. Minimal stable atelectasis noted in the\n bilateral lower lungs, right greater than left. Bilateral chest tubes\n projecting over lung bases with no reaccumulation of pleural effusions or\n pneumothorax. Other lines and tubes in appropriate position.",
"image_path": [
"p16/p16319601/s51150576/bb664e62-f26a58fb-f3f6515a-0cb91fa0-2638766f.jpg"
],
"split": "test"
},
{
"id": "89853b2a-bf88984c-37910d68-2401fca9-884951db",
"study_id": 54811277,
"subject_id": 19182863,
"report": "impression: Findings suggesting mild pulmonary edema. Similar moderate-sized\n right pleural effusion, probably loculated to some extent, with persistent\n lung opacification that can probably be attributed to associated atelectasis. Findings: There is a single-lead pacemaker/ICD device whose lead terminates\n in the right ventricle as before. The tricuspid and aortic valves has been\n replaced. Hazy opacities that are predominantly central within each lung\n suggest mild pulmonary edema. A persistent pleural effusion with loculated\n character appears unchanged on the right, with probable atelectasis opacifying\n a substantial portion of the right lower hemithorax, as before. There is\n probably a trace pleural effusion only on the left. No pneumothorax is\n demonstrated.",
"image_path": [
"p19/p19182863/s54811277/89853b2a-bf88984c-37910d68-2401fca9-884951db.jpg"
],
"split": "test"
},
{
"id": "d4d5dc4c-6021744f-fa9497e5-157fa69b-f68ddb75",
"study_id": 50438261,
"subject_id": 19623993,
"report": "The nasogastric tube is at the level of the pylorus. Nasoenteric\n tube is in place, the tip is out of the image but appears to be post-pyloric. \n The endotracheal tube has been removed. A new left central venous access line\n projects over the confluence of the brachiocephalic veins. Minimal loss in\n lung transparency, potentially caused by fluid overload. No evidence of\n pneumothorax.",
"image_path": [
"p19/p19623993/s50438261/d4d5dc4c-6021744f-fa9497e5-157fa69b-f68ddb75.jpg"
],
"split": "test"
},
{
"id": "6eaf7963-626eb629-9cbd1f78-ed48ebd0-cba58eee",
"study_id": 59044011,
"subject_id": 19389547,
"report": "As compared to the previous radiograph, there is no relevant\n change. The reduced volume of the right hemithorax with areas of lateral\n pleural thickening. The areas of pleural thickening are constant, size and\n morphology. Unchanged perihilar areas of fibrosis. Unchanged size and aspect\n of the cardiac silhouette, no pathologic changes in the left lung.",
"image_path": [
"p19/p19389547/s59044011/6eaf7963-626eb629-9cbd1f78-ed48ebd0-cba58eee.jpg"
],
"split": "test"
},
{
"id": "59a459f5-0bd58411-1d739d65-1d7477bf-92d830cb",
"study_id": 54882267,
"subject_id": 18224196,
"report": "impression: Left lung base atelectasis or scarring. Near-complete interval\n resolution of bilateral pleural effusions. Findings: Mild cardiomegaly is similar to prior. Pleural effusions have nearly\n completely resolved since the prior exam. No focal consolidation or\n pneumothorax. Left lung base linear opacities are compatible with scarring or\n atelectasis. A mitral valve prosthesis is noted. Sternotomy wires are\n intact. Osseous structures are unremarkable.",
"image_path": [
"p18/p18224196/s54882267/59a459f5-0bd58411-1d739d65-1d7477bf-92d830cb.jpg"
],
"split": "test"
},
{
"id": "c02bdcc0-549bf4f3-5f78b267-f547a2ea-ad315318",
"study_id": 51392471,
"subject_id": 16043637,
"report": "impression: No evidence of acute intrathoracic process. Findings: The patient is status post median sternotomy as well as pacemaker\n placement with leads terminating in right atrium and ventricle. There is also\n a aortic valve prosthesis. The heart size remains normal. There are no focal\n opacities concerning for an infectious process. No pleural effusion and no\n pneumothorax.",
"image_path": [
"p16/p16043637/s51392471/c02bdcc0-549bf4f3-5f78b267-f547a2ea-ad315318.jpg"
],
"split": "test"
},
{
"id": "fcbd8e6c-3d25351e-a80195ec-58b15ef8-9c07f9a2",
"study_id": 50036264,
"subject_id": 15131736,
"report": "impression: Findings suggestive of pulmonary vascular congestion. Findings: AP and lateral views of the chest are compared to previous exam\n from ___. There is engorgement of the central pulmonary\n vasculature with indistinct pulmonary vascular markings seen peripherally. \n There is no large confluent consolidation or effusion. Cardiac silhouette is\n enlarged but stable. Osseous and soft tissue structures are unchanged.",
"image_path": [
"p15/p15131736/s50036264/fcbd8e6c-3d25351e-a80195ec-58b15ef8-9c07f9a2.jpg"
],
"split": "test"
},
{
"id": "f0983c7e-5edaaa34-04885b30-b260a522-2451e5cb",
"study_id": 59633653,
"subject_id": 16826047,
"report": "impression: Increase in size of right-sided pleural effusion with pleural\n catheter in place. Expected associated right base atelectasis with\n possibility of infection not excluded. Findings: PA and lateral views of the chest are compared to previous exam\n from ___. Right chest wall port is again seen with catheter tip in\n the lower SVC. Right-sided pleural catheter is seen which appears to course\n in the fissure. Significant amount of right-sided pleural effusion has\n slightly increased since prior with fluid also seen within the major fissure. \n No pneumothorax seen. There is underlying parenchymal opacity as well,\n potentially atelectasis; however, infiltrate is also possible. Left lung is\n grossly clear. Cardiac silhouette is enlarged but stable in configuration. \n Osseous and soft tissue structures are unremarkable.",
"image_path": [
"p16/p16826047/s59633653/f0983c7e-5edaaa34-04885b30-b260a522-2451e5cb.jpg"
],
"split": "test"
},
{
"id": "3084f617-e040a88c-2e4bb84f-d190e19b-fc86d543",
"study_id": 51946836,
"subject_id": 16043637,
"report": "impression: Right PICC line can be traced to the mid SVC, beyond that the line is obscured\n by overlying pacer leads. Findings: Left pectoral pacemaker with leads overlying the right atrium and right\n ventricle. Right PICC line terminates at least at the mid SVC and the tip is\n obscured by overlying pacer leads. There is no pneumothorax. Top normal\n cardiac size. Normal hilar and mediastinal structures. No pneumonia, no\n pulmonary edema. No pleural effusions.",
"image_path": [
"p16/p16043637/s51946836/3084f617-e040a88c-2e4bb84f-d190e19b-fc86d543.jpg"
],
"split": "test"
},
{
"id": "ab104077-b39a8fcb-8c1d8fd5-5a8badb0-be5353a1",
"study_id": 56673612,
"subject_id": 11052935,
"report": "In comparison with the study of ___, the increased opacification at\n the left base has substantially cleared. The suspected area of opacification\n at the right base laterally is barely perceptible at this time. Substantial\n hyperexpansion of the lungs with upper lobe predominant emphysema is again\n noted and there is little change in the appearance of the cardiomediastinal\n silhouette.",
"image_path": [
"p11/p11052935/s56673612/ab104077-b39a8fcb-8c1d8fd5-5a8badb0-be5353a1.jpg"
],
"split": "test"
},
{
"id": "7b764993-32d1c941-d0ddfd50-1022cf30-82cdcfc7",
"study_id": 58306324,
"subject_id": 13475033,
"report": "impression: No acute cardiopulmonary process. Stable cardiomegaly. Stable\n thoracic compression fractures. Findings: Frontal and lateral chest radiographs demonstrate stable\n cardiomegaly and tortuous aorta. No focal opacification concerning for\n pneumonia identified. No pleural effusion or pneumothorax identified. \n Multiple thoracic compression deformities are unchanged since ___. \n Dense calcifications are noted within the right coronary artery as well as the\n aorta.",
"image_path": [
"p13/p13475033/s58306324/7b764993-32d1c941-d0ddfd50-1022cf30-82cdcfc7.jpg"
],
"split": "test"
},
{
"id": "93e655d4-f85397d7-f5a5bd25-3ff6da79-c4342fc6",
"study_id": 59962443,
"subject_id": 16957952,
"report": "impression: Stable diffuse increased interstitial markings with an interval increase in\n opacification in the retrocardiac region, best seen on the lateral view, which\n could be secondary to overlap of structures, however an acute infectious\n process is not excluded. Findings: The patient is status post CABG with intact sternotomy wires. The\n hilar and mediastinal contours appear to be stable with evidence of a tortuous\n aorta. There is stable mild cardiomegaly. There is no pleural effusion or\n pneumothorax. There appears to be a subtle increase in opacification in the\n retrocardiac region, superimposed on a stable mild background of interstitial\n abnormality, best seen on the lateral view.",
"image_path": [
"p16/p16957952/s59962443/93e655d4-f85397d7-f5a5bd25-3ff6da79-c4342fc6.jpg"
],
"split": "test"
},
{
"id": "806524e4-d5ed7e9b-1ac2dada-ba9c4a48-68216237",
"study_id": 53537165,
"subject_id": 11052273,
"report": "impression: No definite evidence for congestive heart failure. Patchy\n streaky opacity in the right lung base likely reflects atelectasis though\n infection is difficult to exclude. Findings: Mild cardiomegaly is unchanged compared to\n the prior study. Aortic knob calcifications are again noted. The mediastinal\n and hilar contours are stable. Previously noted pattern of mild pulmonary\n vascular congestion has essentially resolved. Streaky opacity in the right\n lung base likely reflects atelectasis. No pleural effusion, focal\n consolidation or pneumothorax is identified. No acute osseous abnormality is\n seen.",
"image_path": [
"p11/p11052273/s53537165/806524e4-d5ed7e9b-1ac2dada-ba9c4a48-68216237.jpg"
],
"split": "test"
},
{
"id": "e25c21c7-070fdd75-c67d52b8-9e091b7c-6c560ed4",
"study_id": 58706366,
"subject_id": 13352405,
"report": "impression: Relatively unchanged exam with continued small right pleural effusion, chronic\n elevation of the right hemidiaphragm and right basilar atelectasis. Findings: Cardiac silhouette size is top normal. Mediastinal and hilar contours are\n unchanged. There is no pulmonary vascular congestion. There is a small right\n pleural effusion with chronic elevation of the right hemidiaphragm, unchanged\n compared to the previous exam. Right basilar atelectasis is again\n demonstrated. No left-sided pleural effusion or pneumothorax is present. \n There are multiple old left-sided rib fractures. Multilevel degenerative\n changes are visualized in the thoracic spine. Chronic left AC joint\n dislocation is re- demonstrated.",
"image_path": [
"p13/p13352405/s58706366/e25c21c7-070fdd75-c67d52b8-9e091b7c-6c560ed4.jpg"
],
"split": "test"
},
{
"id": "11bf7fcd-96d58d34-49415fcc-c20c2b7d-1f340544",
"study_id": 57332361,
"subject_id": 11413236,
"report": "impression: No significant interval change. Findings: The patient is status post median sternotomy. Right-sided Port-A-Cath is\n again seen without significant change in position, terminating at the\n cavoatrial junction. Again, there are low lung volumes and minimal bibasilar\n atelectasis. Ovoid calcification projecting over the left mediastinum is\n again seen. Subcentimeter left lower lung rounded calcification is stable and\n may represent a calcified granuloma. No focal consolidation, pleural\n effusion, or evidence of pneumothorax is seen. The cardiac and mediastinal\n silhouettes are stable. There is no overt pulmonary edema.",
"image_path": [
"p11/p11413236/s57332361/11bf7fcd-96d58d34-49415fcc-c20c2b7d-1f340544.jpg"
],
"split": "test"
},
{
"id": "b0663db1-ba5dbce0-63cb3bda-a52f0def-7e5435d9",
"study_id": 53469163,
"subject_id": 12847817,
"report": "impression: 1. Persistent bilateral pleural effusions. \n \n 2. Marked cardiomegaly and pulmonary vascular congestion. Findings: Frontal and lateral chest radiographs were obtained. \n \n There are persistent bilateral small to moderate pleural effusions. There is\n marked cardiomegaly with mild to moderate pulmonary vascular congestion. No\n focal consolidation or pneumothorax is seen. Suture line in the right lower\n lobe and left-sided vascular stent are unchanged. No bony abnormality is\n identified.",
"image_path": [
"p12/p12847817/s53469163/b0663db1-ba5dbce0-63cb3bda-a52f0def-7e5435d9.jpg"
],
"split": "test"
},
{
"id": "608b0d80-17eff322-aea174f9-714f31a8-41683ee7",
"study_id": 50844481,
"subject_id": 17770657,
"report": "An endotracheal tube and right internal jugular\n central venous catheter have been removed. A left internal jugular catheter\n follows a normal course terminating at the confluence of the left\n brachiocephalic and SVC. Surgical clips and mediastinal drains are noted in\n situ.\n \n Lungs are hyperexpanded. There is no new consolidation. Right mid lung\n triangular opacity persists and probably represents fissural fluid. Subtle\n right basilar opacity is similar to the prior exam, probably fluid. Left\n effusion and atelectasis have improved. There is no pneumothorax. \n Cardiomediastinal silhouette is stable.",
"image_path": [
"p17/p17770657/s50844481/608b0d80-17eff322-aea174f9-714f31a8-41683ee7.jpg"
],
"split": "test"
},
{
"id": "20106d63-2c479e81-0d61595c-25ef9723-cba07432",
"study_id": 51031461,
"subject_id": 16409152,
"report": "ONE PORTABLE SUPINE AP VIEW OF THE CHEST. Right internal jugular\n catheter ends near the cavoatrial junction. NG tube is seen in the stomach\n with last side port below the GE junction. The lung findings are unchanged\n compared to study done two hours prior.",
"image_path": [
"p16/p16409152/s51031461/20106d63-2c479e81-0d61595c-25ef9723-cba07432.jpg"
],
"split": "test"
},
{
"id": "928a3662-7a9bc2d9-1808833b-79fd5d7b-76aabf9d",
"study_id": 52697942,
"subject_id": 15259244,
"report": "impression: No significant interval change since ___ noting left basilar\n opacity due to combination of pleural effusion with underlying atelectasis and\n possible consolidation. Findings: Single portable view of the chest is compared to previous exam from\n ___. Compared to prior, there has been no significant interval\n change. Dense retrocardiac opacity is again seen silhouetting of the\n hemidiaphragm. The right lung remains grossly clear. Mild pulmonary vascular\n congestion is unchanged. Cardiac silhouette is enlarged, but stable and\n notable for a prosthetic device.",
"image_path": [
"p15/p15259244/s52697942/928a3662-7a9bc2d9-1808833b-79fd5d7b-76aabf9d.jpg"
],
"split": "test"
},
{
"id": "ac8313a2-9e5439a8-e287d978-72c66b71-8d91da34",
"study_id": 59828891,
"subject_id": 13896515,
"report": "impression: Moderate left pleural effusion with overlying atelectasis, underlying\n consolidation not excluded. Similar pulmonary edema. Findings: Patient is status post median sternotomy. Left-sided pacer device is grossly\n stable in position. There is a moderate left pleural effusion with overlying\n atelectasis, left base consolidation is not excluded. Similar pulmonary edema\n persists, possibly asymmetric on the left. No right pleural effusion is seen.\n There is no pneumothorax. Cardiac and mediastinal silhouettes are stable.",
"image_path": [
"p13/p13896515/s59828891/ac8313a2-9e5439a8-e287d978-72c66b71-8d91da34.jpg"
],
"split": "test"
},
{
"id": "5b73306f-64ed83f7-dc6e0957-f8d1a9b2-bdd393f3",
"study_id": 59631450,
"subject_id": 14147787,
"report": "impression: Stable bilateral upper lung opacities, most likely local\n fibrosis. No evidence of disease progression. Findings: Again seen are stable bilateral linear opacities in the upper lungs\n with suggestion of local fibrosis. There is no evidence of fibrosis in other\n lung zones or progression of disease. There is no hilar adenopathy, focal\n consolidation, pleural effusion, or pneumothorax. No newly appeared\n micronodules. The cardiomediastinal silhouette is normal.",
"image_path": [
"p14/p14147787/s59631450/5b73306f-64ed83f7-dc6e0957-f8d1a9b2-bdd393f3.jpg"
],
"split": "test"
},
{
"id": "e3ba16c1-e0005eef-0c0e37cd-1ad23c91-beac16e8",
"study_id": 59196954,
"subject_id": 11880923,
"report": "Comparison is made to the prior study performed at 4:35 a.m. on\n ___.\n \n There is a right-sided catheter with the distal lead tip at the cavoatrial\n junction. There is a left IJ central venous line with the distal lead tip in\n the mid SVC. The endotracheal tube tip is 4.5 cm above the carina. The\n feeding tube whose distal tip is below the GE junction. These tubes are all\n unchanged in position. There is stable cardiomegaly. There is mild improved\n aeration at the lung bases. There remain bilateral pleural effusions. There\n are no signs for overt pulmonary edema or pneumothoraces.",
"image_path": [
"p11/p11880923/s59196954/e3ba16c1-e0005eef-0c0e37cd-1ad23c91-beac16e8.jpg"
],
"split": "test"
},
{
"id": "b5d3da06-fd20e016-8b1924e1-3ff9ceed-fb365036",
"study_id": 59610928,
"subject_id": 16957952,
"report": "impression: Diffuse increased interstitial markings are compatible with\n minimal interstitial edema. No focal opacities concerning for pneumonia. Findings: There are increased interstitial markings bilaterally not\n significantly changed from ___, but no focal opacities. Heart size is\n top normal. The aorta is tortuous. There is no pleural effusion or\n pneumothorax. Sternotomy wires as well as mediastinal surgical clips from\n prior CABG are re-demonstrated and unchanged in position.",
"image_path": [
"p16/p16957952/s59610928/b5d3da06-fd20e016-8b1924e1-3ff9ceed-fb365036.jpg"
],
"split": "test"
},
{
"id": "1fba2de2-36345a9e-ea2ef064-76c702c3-b80e6127",
"study_id": 59219088,
"subject_id": 16853729,
"report": "impression: Mild pulmonary vascular congestion and small left pleural\n effusion. More focal opacities in the lung bases may reflect atelectasis,\n though infection in these regions cannot be completely excluded. Findings: There are low lung volumes. The heart\n size remains moderately enlarged. The aorta is tortuous but stable. There is\n mild pulmonary vascular congestion with perihilar haziness. More focal\n opacities in the lung bases may reflect atelectasis, though infection in these\n regions cannot be completely excluded. Small left pleural effusion appears\n similar compared to the prior study. No pneumothorax is identified. Mild\n loss of height anteriorly of an upper lumbar vertebral body is unchanged.",
"image_path": [
"p16/p16853729/s59219088/1fba2de2-36345a9e-ea2ef064-76c702c3-b80e6127.jpg"
],
"split": "test"
},
{
"id": "f6a45850-afbc320a-ab118fd9-85e788d6-d88d5060",
"study_id": 56749558,
"subject_id": 13263843,
"report": "impression: Interval resolution of right pleural effusion. Findings: Frontal and lateral views of the chest were obtained. The patient\n is status post right upper chest wall resection, right upper lobectomy with\n right apical scarring and upward traction of the right hilum from radiation\n fibrosis, all unchanged. There is no pleural effusion or pneumothorax. The\n left lung is clear. Heart size is normal.",
"image_path": [
"p13/p13263843/s56749558/f6a45850-afbc320a-ab118fd9-85e788d6-d88d5060.jpg"
],
"split": "test"
},
{
"id": "1a0662d4-8bee75af-c5c452a9-4b43c737-b74d27c1",
"study_id": 59735304,
"subject_id": 11413236,
"report": "impression: Bibasilar atelectasis. No convincing evidence for pneumonia. Findings: AP portable upright view of the chest. Right chest wall Port-A-Cath again\n noted with catheter tip extending to the upper SVC region. Midline sternotomy\n wires are again noted. There is a calcified ovoid structure projecting over\n the mediastinum likely a calcified lymph node. There is mild basilar\n atelectasis noted bilaterally. No focal consolidation concerning for\n pneumonia. No large effusion or pneumothorax is seen. Cardiomediastinal\n silhouette is stable. Bony structures are intact.",
"image_path": [
"p11/p11413236/s59735304/1a0662d4-8bee75af-c5c452a9-4b43c737-b74d27c1.jpg"
],
"split": "test"
},
{
"id": "f7995b00-70025839-1b735979-92983f8a-5fb639f8",
"study_id": 56055109,
"subject_id": 13475033,
"report": "impression: No significant interval change. Stable diffuse increase in interstitial\n markings consistent with chronic lung disease. Findings: There still diffuse increase in interstitial markings bilaterally consistent\n with chronic interstitial lung disease. No new focal consolidation is seen. \n No pleural effusion or pneumothorax is seen. The cardiac and mediastinal\n silhouettes are grossly stable.",
"image_path": [
"p13/p13475033/s56055109/f7995b00-70025839-1b735979-92983f8a-5fb639f8.jpg"
],
"split": "test"
},
{
"id": "49d3507c-e1c8d85f-5d7f8127-2f2e14f5-a84a6a13",
"study_id": 59521539,
"subject_id": 16662264,
"report": "As compared to the previous radiograph from ___,\n there is substantial improvement of the pre-existing pneumonia. On the\n current image, small foci of remnant pneumonia are seen in the pericardiac\n areas of the lingula, and on the lateral image, in the middle lobe. There is\n no evidence of complications, notably no pleural effusion or lymphadenopathy. \n Otherwise, the lung parenchyma is normal. There is no hilar or mediastinal\n abnormality. Normal size and shape of the cardiac silhouette.",
"image_path": [
"p16/p16662264/s59521539/49d3507c-e1c8d85f-5d7f8127-2f2e14f5-a84a6a13.jpg"
],
"split": "test"
},
{
"id": "f3686ece-bb54acba-7f3b1ce4-b9166b5f-cd9b52c2",
"study_id": 50457087,
"subject_id": 11052935,
"report": "A new area of consolidation has developed in the left lower lobe,\n and is concerning for developing pneumonia considering the clinical suspicion\n for this entity. Additional nonspecific patchy opacity at the periphery of\n the right lung base could reflect focal atelectasis, or an additional site of\n infection. Severe upper lobe predominant emphysema is again demonstrated. \n Cardiomediastinal contours are normal. No pleural effusion or pneumothorax is\n evident.",
"image_path": [
"p11/p11052935/s50457087/f3686ece-bb54acba-7f3b1ce4-b9166b5f-cd9b52c2.jpg"
],
"split": "test"
},
{
"id": "af1457be-7507046a-550303e6-7079a0d3-56b7ab55",
"study_id": 51326934,
"subject_id": 19907884,
"report": "In comparison with the study of ___, the monitoring and support\n devices have been removed. Continued low lung volumes but no definite\n evidence of pneumonia, pleural effusion, or vascular congestion.\n \n As on the prior study, there is some poor definition of the right heart border\n that could well represent crowding of vessels.",
"image_path": [
"p19/p19907884/s51326934/af1457be-7507046a-550303e6-7079a0d3-56b7ab55.jpg"
],
"split": "test"
},
{
"id": "73f1035a-9d57466e-92c2b0b1-5ee3d31c-78ad1ad4",
"study_id": 58191597,
"subject_id": 19759491,
"report": "impression: Findings is compatible with mild interstitial edema. Findings: PA and lateral views of the chest. Triple lead pacing device along the right\n chest wall is again noted with leads in unchanged position. Mitral valvular\n replacement again noted. Prominence of the interstitial markings are again\n seen without evidence of focal consolidation or overt pulmonary edema. There\n is no large pleural effusion noting persistent probable fluid within the major\n fissure on the lateral. Degree of cardiomegaly has not changed. No acute\n osseous abnormalities detected.",
"image_path": [
"p19/p19759491/s58191597/73f1035a-9d57466e-92c2b0b1-5ee3d31c-78ad1ad4.jpg"
],
"split": "test"
},
{
"id": "ede252ee-83066d8a-376961c0-b07de3b1-0dfeb1e0",
"study_id": 50282926,
"subject_id": 15259244,
"report": "impression: Stable chronic cardiomegaly. Mild improvement in the chronic\n moderate-sized left pleural effusion and left basal atelectasis. Findings: The cardiomediastinal and hilar contours are stable, with moderate\n cardiomegaly. Multiple intact sternotomy wires, mediastinal surgical clips,\n and prosthetic aortic valve are noted. There is minimal improvement in a\n chronic moderate-sized left pleural effusion. No pneumothorax is seen. Faint\n opacity right base laterally appears to represent residua from ___ xray. \n Bibasal opacities, left greater than right, likely represents atelectasis. \n Ppossible background chronic lung disease. Faint opacity over left upper\n quadrant of abdomen may represent residual contrast in te stomach. No free air\n seen beneath the diaphragm.\n \n No obvious displaced rib fractures are seen. If there is a high clinical\n concern for a nondisplaced rib fracture, dedicated rib series scan be\n performed with a marker placed at the site of maximum tenderness.",
"image_path": [
"p15/p15259244/s50282926/ede252ee-83066d8a-376961c0-b07de3b1-0dfeb1e0.jpg"
],
"split": "test"
},
{
"id": "550025f0-fb28013b-e174e563-a9c2dc35-c3f0b4d0",
"study_id": 51762961,
"subject_id": 15114531,
"report": "In comparison with the study of ___, there is no change or evidence\n of acute cardiopulmonary disease. The lungs are clear and there is no\n vascular congestion or pleural effusion.\n \n Of incidental note is dilatation of the trachea consistent with the patient's\n known tracheomalacia. The esophageal capsule is no longer present and there\n are surgical clips in the upper abdomen.",
"image_path": [
"p15/p15114531/s51762961/550025f0-fb28013b-e174e563-a9c2dc35-c3f0b4d0.jpg"
],
"split": "test"
},
{
"id": "d169abca-f4a7073b-db2b836e-295d8b8e-3c68c604",
"study_id": 55034480,
"subject_id": 13896515,
"report": "impression: 1. Moderate left pleural effusion with moderate pulmonary edema, worsened\n compared to the most recent prior study.\n 2. Mild to moderate cardiomegaly. Findings: There is mild to moderate cardiomegaly. There is a moderate left pleural\n effusion with no right pleural effusion. There is no pneumothorax. Moderate\n pulmonary edema is seen, worse compared to the most recent prior study but\n similar compared to the study from ___. There has been interval\n removal of the right PICC. Left axillary pacemaker is again noted.",
"image_path": [
"p13/p13896515/s55034480/d169abca-f4a7073b-db2b836e-295d8b8e-3c68c604.jpg"
],
"split": "test"
},
{
"id": "c190fb7d-da5b3a51-5f074369-736f62a6-589d6474",
"study_id": 57219522,
"subject_id": 16662264,
"report": "impression: Improvement of multifocal infiltrates but persistent densities in\n right middle lobe and peripheral lingula. Further followup examination must\n be guided by patient's symptomatology. Findings: PA and lateral chest views were obtained with patient in upright\n position. Comparison is made with the next preceding similar study of\n ___. The heart size remains unchanged and is within normal limits. \n Unremarkable position of previously described left-sided PICC line terminating\n in mid portion of SVC. The pulmonary vasculature is not congested and no\n pneumothorax can be identified. On previous examinations remaining multifocal\n density have generally improved. In particular, a lesion identified on the\n last examination overlying the right upper lobe area laterally (third right\n intercostal space) has cleared up almost completely. Densities located in the\n right middle lobe as well as those seen in the left upper lobe lingula\n persist, but have also undergone a slight improvement. Again, no pneumothorax\n has developed, no new infiltrates are seen and the lateral and posterior\n pleural sinuses remain free from any pleural effusion.",
"image_path": [
"p16/p16662264/s57219522/c190fb7d-da5b3a51-5f074369-736f62a6-589d6474.jpg"
],
"split": "test"
},
{
"id": "d240a096-eb1996ea-8a08a168-367aa57b-96adf6ad",
"study_id": 54733030,
"subject_id": 16855430,
"report": "impression: Pulmonary edema, likely with trace pleural effusions. Findings: Portable AP upright chest radiograph is obtained. Lung volumes are\n low. There is mild ground-glass opacity involving both lungs concerning for\n pulmonary edema. No large pleural effusions are seen, though trace effusions\n are likely present. Heart size appears top normal. No pneumothorax. Bones\n appear intact.",
"image_path": [
"p16/p16855430/s54733030/d240a096-eb1996ea-8a08a168-367aa57b-96adf6ad.jpg"
],
"split": "test"
},
{
"id": "bf010702-69e984da-d0e9d988-cb6dbed8-1f759220",
"study_id": 58107496,
"subject_id": 13606683,
"report": "impression: Mildly indistinct pulmonary vascular markings suggestive of mild\n failure without frank pulmonary edema. Findings: PA and lateral views of the chest are compared to previous exams\n from ___ and ___.\n \n Linear opacities at the left greater than right base are suggestive of\n subsegmental atelectasis. Mildly indistinct pulmonary vascular markings are\n seen suggestive of mild failure; however, there is no definite confluent\n consolidation. Small left pleural effusion is seen. Cardiac silhouette is\n enlarged but stable. Again seen is a prosthetic valve. Median sternotomy\n wires are again seen with fracture at the inferior most wire. Osseous and\n soft tissue structures are otherwise unremarkable.",
"image_path": [
"p13/p13606683/s58107496/bf010702-69e984da-d0e9d988-cb6dbed8-1f759220.jpg"
],
"split": "test"
},
{
"id": "c33529b6-0bc71076-a10b08f6-ef0692d4-2c28d98f",
"study_id": 55782701,
"subject_id": 17318449,
"report": "impression: No acute cardiopulmonary process. Findings: Frontal and lateral views of the chest. The lungs are clear of\n focal consolidation or large effusion, noting that the right costophrenic\n angle is excluded from the field of view on the lateral view. No overt\n pulmonary edema. Cardiomediastinal silhouette is enlarged but stable. Median\n sternotomy wires are again noted. Hypertrophic changes seen in the spine.",
"image_path": [
"p17/p17318449/s55782701/c33529b6-0bc71076-a10b08f6-ef0692d4-2c28d98f.jpg"
],
"split": "test"
},
{
"id": "1b02ffa5-a6da06e3-9063b9ef-5e540245-c18323b5",
"study_id": 54742755,
"subject_id": 19991135,
"report": "impression: No acute cardiopulmonary abnormality. Bullous emphysema. Findings: Heart size is borderline enlarged but unchanged. Mediastinal and hilar\n contours are normal. Pulmonary vasculature is normal. Hyperinflation of the\n lungs with bullous emphysematous changes are again noted in the upper lobes.\n Lungs are clear without focal consolidation. No pleural effusion or\n pneumothorax is present. Pulmonary vasculature is normal. Right-sided rib cage\n deformities are chronic. Partially visualized is cervical spinal fusion\n hardware.",
"image_path": [
"p19/p19991135/s54742755/1b02ffa5-a6da06e3-9063b9ef-5e540245-c18323b5.jpg"
],
"split": "test"
},
{
"id": "9911ed32-2bf726d7-dfcdceb1-dc248f4e-b62bb269",
"study_id": 53053450,
"subject_id": 12185775,
"report": "As compared to the previous radiograph, the pre-existing opacities\n at the right lung base have improved. The left lung base is unchanged. \n Overall, the signs indicative of pulmonary edema have slightly decreased in\n severity but they are still clearly present. Unchanged moderate cardiomegaly\n and left calcified lung granulomas.",
"image_path": [
"p12/p12185775/s53053450/9911ed32-2bf726d7-dfcdceb1-dc248f4e-b62bb269.jpg"
],
"split": "test"
},
{
"id": "64613c7b-ce9fb911-c2eb42ab-41a905ea-97ce9a9d",
"study_id": 56362705,
"subject_id": 16116557,
"report": "impression: No acute cardiothoracic process. Findings: The lungs are clear, the cardiomediastinal silhouette and hila are\n normal. There is no pleural effusion and no pneumothorax. A replaced mitral\n valve is seen.",
"image_path": [
"p16/p16116557/s56362705/64613c7b-ce9fb911-c2eb42ab-41a905ea-97ce9a9d.jpg"
],
"split": "test"
},
{
"id": "8d361e7d-f4f46fc7-956ef2b6-bc506025-0df660c3",
"study_id": 58147681,
"subject_id": 16313531,
"report": "In comparison with the study of ___, there are continued areas of\n increased opacification bilaterally consistent with some combination of\n aspiration and volume loss. Increasing prominence of pulmonary vessels is\n consistent with overhydration or worsening cardiac function. Monitoring and\n support devices are in unchanged position, with the right PICC line again at\n the cavoatrial junction or in the right atrium.",
"image_path": [
"p16/p16313531/s58147681/8d361e7d-f4f46fc7-956ef2b6-bc506025-0df660c3.jpg"
],
"split": "test"
},
{
"id": "91db5745-87b0042c-4728fa53-e5352d85-501dae1c",
"study_id": 55564287,
"subject_id": 14236258,
"report": "impression: No acute cardiopulmonary process. Findings: AP and lateral views of the chest are compared to previous exam\n from ___. Dual-lumen left subclavian line is in stable position.\n The lungs are clear of consolidation. Trace blunting of the left costophrenic\n angle again seen. There is no right-sided pleural effusion. \n Cardiomediastinal silhouette is stable. Surgical clips project over the\n thoracic inlet bilaterally.\n \n Osseous structures again notable for bilateral, old posterior healed rib\n fractures and mild wedging of mid thoracic vertebral bodies, unchanged since\n ___. Degenerative changes again seen at the shoulders bilaterally\n including calcification in the region of the right coracoclavicular region.",
"image_path": [
"p14/p14236258/s55564287/91db5745-87b0042c-4728fa53-e5352d85-501dae1c.jpg"
],
"split": "test"
},
{
"id": "bb42be73-33be1577-a742e6e6-9c47b56b-95a9659e",
"study_id": 50170739,
"subject_id": 18893199,
"report": "impression: No acute cardiopulmonary abnormality. Findings: A cardiac conduction device is contiguous with a lead which terminates in the\n right atrium. There is no focal consolidation. There is no pneumothorax. \n The cardiomediastinal silhouette is unremarkable.",
"image_path": [
"p18/p18893199/s50170739/bb42be73-33be1577-a742e6e6-9c47b56b-95a9659e.jpg"
],
"split": "test"
},
{
"id": "35ba5821-6f988e43-c7ce7779-9947c2dc-064358ad",
"study_id": 56573421,
"subject_id": 19549821,
"report": "The lung volumes are normal. Mild bilateral apical scarring. \n Borderline size of the cardiac silhouette without pulmonary edema. No overt\n pneumonia. Small basal lung nodule projecting over the right costophrenic\n sinus, unchanged as compared to the previous examination.\n \n No inflammatory or edematous change in the lung parenchyma.\n \n Normal appearance of the mediastinum.",
"image_path": [
"p19/p19549821/s56573421/35ba5821-6f988e43-c7ce7779-9947c2dc-064358ad.jpg"
],
"split": "test"
},
{
"id": "f9a786b3-b5473ac8-3f0d1596-bc19198f-2a6ccc1c",
"study_id": 51478052,
"subject_id": 14851532,
"report": "As compared to the previous radiograph, the bilateral areas of\n atelectasis at the lung bases, left more than right, are present in unchanged\n manner. Minimal postoperative opacity at the left lung base that should\n receive attention on further followups. The right internal jugular vein\n catheter is unchanged. No overt pulmonary edema. No evidence of\n pneumothorax. Borderline size of the cardiac silhouette.",
"image_path": [
"p14/p14851532/s51478052/f9a786b3-b5473ac8-3f0d1596-bc19198f-2a6ccc1c.jpg"
],
"split": "test"
},
{
"id": "dca8209b-bd3fa52c-e5ca606b-9a0cfd8f-006336b3",
"study_id": 50620952,
"subject_id": 12475198,
"report": "Allowing for differences in technique and projection, there has\n been little change in the appearance of the chest since the recent study of\n one day earlier. Widespread heterogeneous areas of consolidation continue to\n affect the right lung more than the left. There has been slight worsening in\n the right lung base with otherwise no relevant changes.",
"image_path": [
"p12/p12475198/s50620952/dca8209b-bd3fa52c-e5ca606b-9a0cfd8f-006336b3.jpg"
],
"split": "test"
},
{
"id": "2d0d0dd1-758ad05c-5f33e8fa-08a1e0dc-63d862be",
"study_id": 54934220,
"subject_id": 10268877,
"report": "Comparison is made to previous study from ___.\n \n There is an endotracheal tube whose distal tip is 6.2 cm above the carina\n appropriately sited. There is a left-sided IJ line with distal lead tip in\n the mid SVC. There is a nasogastric tube whose tip and sideport are below the\n GE junction.\n \n There is a persistent left retrocardiac opacity. There is some atelectasis at\n the left lung base. There is improved aeration at the right lung base. No\n pneumothoraces are seen.",
"image_path": [
"p10/p10268877/s54934220/2d0d0dd1-758ad05c-5f33e8fa-08a1e0dc-63d862be.jpg"
],
"split": "test"
},
{
"id": "49177e16-0383da48-c2a81ed9-77e7a7c0-bbe8c9cb",
"study_id": 58807210,
"subject_id": 13762730,
"report": "impression: Right middle lobe and lingular pneumonia. Findings: There are parenchymal opacities in the right middle lobe. There\n are also ___-___ opacities in the region of the lingula. Dual-chamber\n pacer in the left upper chest terminates in the right atrium and ventricle,\n stable. Mild cardiomegaly and tortuous aorta is unchanged. There is no\n pleural effusion or pneumothorax. Hyperexpansion and flattened hemidiphragms\n suggest COPD.",
"image_path": [
"p13/p13762730/s58807210/49177e16-0383da48-c2a81ed9-77e7a7c0-bbe8c9cb.jpg"
],
"split": "test"
},
{
"id": "40b2ad97-b8cd3c49-7a1658b6-79be29bb-676d3481",
"study_id": 55492069,
"subject_id": 13352405,
"report": "Comparison is made to the prior study from ___.\n \n There are two right-sided chest tubes with distal tips at the apex and at the\n base. These are unchanged in position. No pneumothoraces are seen on either\n side. There is elevation of the right hemidiaphragm and volume loss on the\n right side. No signs for overt pulmonary edema is seen. There is some\n atelectasis at the lung bases.",
"image_path": [
"p13/p13352405/s55492069/40b2ad97-b8cd3c49-7a1658b6-79be29bb-676d3481.jpg"
],
"split": "test"
},
{
"id": "615687f6-9c68c0c3-ea00fb31-0987abc8-6d4be9c7",
"study_id": 59698565,
"subject_id": 18570152,
"report": "impression: Right lower lobe and left infrahilar opacities, right greater\n than left, in the appropriate clinical setting, raises concern for pneumonia. \n Recommend followup to resolution. Possible 0.9 cm nodular opacity along the\n superior aspect of the right lower lung opacity, could relate to\n consolidation, but pulmonary nodule not excluded. Recommend followup chest\n radiographs after appropriate therapy and if finding remains, chest CT.\n \n Left suprahilar opacity, which could be a second site of infection or relate\n to mild volume overload.\n \n Pulmonary vascular engorgement. Enlarged cardiac silhouette. Findings: Frontal and lateral views of the chest are obtained. Right lower\n lobe opacity is worrisome for consolidation, possibly due to pneumonia. \n Along the superior aspect of the right lower lung consolidation, there is a\n 0.9-cm nodular opacity, projecting between the posterior right sixth and\n seventh ribs, which could relate to consolidation or an underlying pulmonary\n nodule is not excluded. Recommend followup chest radiograph after appropriate\n therapy and if finding remains, chest CT. There is also a left suprahilar\n opacity, which could be a second site of infection or relate to mild volume\n overload. There is central pulmonary vascular engorgement. No large pleural\n effusion or pneumothorax is seen. Single-lead left-sided pacemaker is seen\n with leads in the expected position of the right ventricle. The cardiac\n silhouette is enlarged.",
"image_path": [
"p18/p18570152/s59698565/615687f6-9c68c0c3-ea00fb31-0987abc8-6d4be9c7.jpg"
],
"split": "test"
},
{
"id": "8a429357-0b188f6b-54307015-8a57c7cd-31b1ed38",
"study_id": 55557117,
"subject_id": 13078497,
"report": "As compared to the previous radiograph, there is no relevant\n change. Widespread bilateral parenchymal opacities, combined to an enlarged\n cardiac silhouette. The monitoring and support devices are in constant\n position.",
"image_path": [
"p13/p13078497/s55557117/8a429357-0b188f6b-54307015-8a57c7cd-31b1ed38.jpg"
],
"split": "test"
},
{
"id": "ab649acd-239dc728-c8404656-da6cbf96-fb31a0b6",
"study_id": 55939586,
"subject_id": 17396677,
"report": "As compared to the previous radiograph, there is complete clearing\n of the pre-existing opacity in the right lower lobe. No evidence of current\n pneumonia. No other parenchymal changes. Normal size of the cardiac\n silhouette. No pleural effusion. No hilar or mediastinal abnormalities.",
"image_path": [
"p17/p17396677/s55939586/ab649acd-239dc728-c8404656-da6cbf96-fb31a0b6.jpg"
],
"split": "test"
},
{
"id": "ce6c73a2-bfbdbdf8-f7f014a2-bfffc5e3-232d2d80",
"study_id": 58056585,
"subject_id": 18067737,
"report": "impression: 1. Left pleural effusion which appears increased since the prior study. Left\n retrocardiac opacity may relate to combination of effusion and atelectasis,\n however underlying consolidation cannot be excluded.\n 2. Left perihilar opacity consistent with known mass and parenchymal\n scarring. Grossly stable appearance of the left perihilar region. Findings: Frontal and lateral views of chest were obtained. Dual-lead\n left-sided pacemaker is again seen with leads extending to the expected\n positions of the right atrium and right ventricle. Left perihilar opacity is\n again seen, grossly similar in appearance, consistent with known mass and\n parenchymal scarring. There is persistent blunting of the left costophrenic\n angle which appears slightly increased since the prior study. Left\n retrocardiac opacity may relate to combination of effusion and atelectasis,\n however underlying consolidation cannot be excluded.\n The right lung is clear.",
"image_path": [
"p18/p18067737/s58056585/ce6c73a2-bfbdbdf8-f7f014a2-bfffc5e3-232d2d80.jpg"
],
"split": "test"
},
{
"id": "92e316b6-8facf11c-bce58686-26309d9a-afc8bed3",
"study_id": 57361130,
"subject_id": 16826047,
"report": "impression: Significant progression of a large right pleural effusion. \n Discussed with Dr ___ ___ phone at ___. Findings: A right pleural effusion has increased since ___ and is now\n large. The left lung is clear. No left effusion or pneumothorax is present. \n A right-sided Port-A-Cath tip remains in the mid SVC. Cardiomegaly is\n unchanged.",
"image_path": [
"p16/p16826047/s57361130/92e316b6-8facf11c-bce58686-26309d9a-afc8bed3.jpg"
],
"split": "test"
},
{
"id": "f9af4910-694f5e1f-75e4a512-0bd1c6dc-e4616d88",
"study_id": 57086484,
"subject_id": 14851532,
"report": "impression: 1. Increased right pleural effusion since the prior radiographs.\n 2. Moderate cardiomegaly, stable.\n 3. Left suprahilar opacity is attributed to postsurgical scarring and a\n previously seen consolidation, however is less well evaluated on the current\n radiograph. Frontal and lateral projections can be obtained for further\n evaluation as needed. Findings: Heart size is enlarged but stable. There are chronic coarsened interstitial\n markings. The opacity in the left suprahilar region is partially attributed\n to postsurgical scarring as well as the previously seen consolidation, however\n is not well evaluated on this single frontal projection.\n Right pleural effusion is increased, now small to moderate.",
"image_path": [
"p14/p14851532/s57086484/f9af4910-694f5e1f-75e4a512-0bd1c6dc-e4616d88.jpg"
],
"split": "test"
},
{
"id": "10a3cd75-c86d7f2a-f350e7bc-b872fc06-79271f33",
"study_id": 51820068,
"subject_id": 13475033,
"report": "impression: No superimposed pneumonia in this patient with known ILD. Findings: PA and lateral views of the chest were provided. As seen on\n multiple prior exams, there is generalized chronic interstitial fibrosis\n manifested by coarsened interstitial markings which is compatible with\n provided clinical history of ILD. There is no superimposed consolidation to\n suggest pneumonia. No pleural effusion or pneumothorax. The\n cardiomediastinal silhouette is stable. No free air below the right\n hemidiaphragm. An old left mid shaft clavicle deformity is again noted. No\n acute bony abnormalities.",
"image_path": [
"p13/p13475033/s51820068/10a3cd75-c86d7f2a-f350e7bc-b872fc06-79271f33.jpg"
],
"split": "test"
},
{
"id": "c148002c-a0674884-d784b291-762232a4-a10fa5aa",
"study_id": 56483572,
"subject_id": 19075045,
"report": "In comparison with the study of ___, the monitoring and support\n devices remain in place. There may be mild increased aeration in the left\n upper zone. Retrocardiac opacification is consistent with volume loss in the\n left lower lobe. Hazy opacification bilaterally is consistent with pleural\n effusions, and there is some increase in pulmonary venous pressure.",
"image_path": [
"p19/p19075045/s56483572/c148002c-a0674884-d784b291-762232a4-a10fa5aa.jpg"
],
"split": "test"
},
{
"id": "db368d36-8c00c286-fd73c287-46b788dc-3238c890",
"study_id": 56237499,
"subject_id": 14213287,
"report": "impression: No acute findings. Given findings on CT dated ___, a\n nonemergent 3 month f/u chest CT is appropriate to ensure complete resolution\n and/or stability of nodules per ___ guidelines. Findings: Lateral views of the chest were obtained. The lungs appear clear\n bilaterally. The previously detected opacity in the left lower lung appears\n to have resolved, though evaluation on a chest radiograph is suboptimal to\n assess complete resolution. Would recommend non-emergent CT of the chest to\n ensure resolution of the previously detected lingular opacity as well as\n multiple additional lung nodules described in detail on prior CT chest.\n Cardiomediastinal sillouhette appears normal. Bony structures are intact.",
"image_path": [
"p14/p14213287/s56237499/db368d36-8c00c286-fd73c287-46b788dc-3238c890.jpg"
],
"split": "test"
},
{
"id": "417162c9-a460e98a-56bf6ab3-b6c591a2-86230b6d",
"study_id": 56051681,
"subject_id": 11924226,
"report": "impression: No signs of pneumonia. Findings: PA and lateral views of the chest provided demonstrate no focal\n consolidation, effusion or pneumothorax. The cardiomediastinal silhouette is\n normal. Bony structures are intact. There is no free air below the right\n hemidiaphragm. Mild degenerative change in the mid thoracic spine noted on\n the lateral projection.",
"image_path": [
"p11/p11924226/s56051681/417162c9-a460e98a-56bf6ab3-b6c591a2-86230b6d.jpg"
],
"split": "test"
},
{
"id": "a9493b3c-4d63defd-55b09266-3147f2af-e73caba1",
"study_id": 52169517,
"subject_id": 17163861,
"report": "impression: No acute cardiopulmonary process. Findings: The lungs are clear. The hilar and cardiomediastinal contours are\n normal. There is no pneumothorax or pleural effusion. Pulmonary vascularity\n is normal. A dual-lead pacemaker is present.",
"image_path": [
"p17/p17163861/s52169517/a9493b3c-4d63defd-55b09266-3147f2af-e73caba1.jpg"
],
"split": "test"
},
{
"id": "555d2282-7ca48bd5-2e68791a-778b0044-8fa2ce6f",
"study_id": 58936592,
"subject_id": 17838301,
"report": "impression: Findings consistent with mild pulmonary edema. Findings: The heart is moderately enlarged. The mediastinal and hilar\n contours appear unchanged, allowing for differences in technique. A band-like\n opacity projecting over the left mid lung suggests minor atelectasis or\n scarring. More generally, there is mild increased opacification with\n indistinct pulmonary vascularity suggesting mild pulmonary vascular congestion\n without definite focal opacities. Calcified pleural plaques are suspected.",
"image_path": [
"p17/p17838301/s58936592/555d2282-7ca48bd5-2e68791a-778b0044-8fa2ce6f.jpg"
],
"split": "test"
},
{
"id": "5142f79d-ca2bee0e-d70061cd-e31c5917-98f78f0e",
"study_id": 51096107,
"subject_id": 19623993,
"report": "impression: Post-pyloric positioning of the Dobbhoff tube in the region of\n the second portion of the duodenum. Findings: The Dobbhoff tube has been advanced distally from its position on\n prior abdominal radiograph. The tip of the Dobhoff tube terminates in the\n region of the second portion of the duodenum. \n \n The heart remains mildly enlarged with bilateral hilar opacification. A right\n supraclavicular central venous catheter is noted terminating in the SVC. \n There is no pneumothorax. There is no abdominal free air.",
"image_path": [
"p19/p19623993/s51096107/5142f79d-ca2bee0e-d70061cd-e31c5917-98f78f0e.jpg"
],
"split": "test"
},
{
"id": "d17e21ba-cf76b4d5-e90b2776-43be3667-dacf2f6f",
"study_id": 59053386,
"subject_id": 15186992,
"report": "As compared to the previous radiograph, there is no relevant\n change. Extensive emphysematous lung parenchymal destruction in both upper\n lobes, right more than left. Subsequent distortion of vascular and airway\n structures at the lung bases.\n \n No pulmonary edema. No pneumonia. Borderline size of the cardiac silhouette.",
"image_path": [
"p15/p15186992/s59053386/d17e21ba-cf76b4d5-e90b2776-43be3667-dacf2f6f.jpg"
],
"split": "test"
},
{
"id": "2a166b16-c5106df5-cf2e822c-23c915b4-983161ad",
"study_id": 50165831,
"subject_id": 15131736,
"report": "impression: Persistent prominence of the hila suggesting pulmonary vascular\n engorgement/enlargement of the central pulmonary arteries, similar to prior,\n with possible mild increase in vascular congestion as compared to prior study. Findings: There is persistent prominence of the hila suggesting vascular engorgement\n with possible mild increase in vascular congestion as compared to the prior\n study. No new focal consolidation is seen. There is no large pleural effusion\n or pneumothorax. The cardiac and mediastinal silhouettes are stable.",
"image_path": [
"p15/p15131736/s50165831/2a166b16-c5106df5-cf2e822c-23c915b4-983161ad.jpg"
],
"split": "test"
},
{
"id": "c1ca2269-888c6d31-99903c19-c02256b7-390f38a1",
"study_id": 52019812,
"subject_id": 15032623,
"report": "impression: No acute cardiopulmonary process. Findings: AP and lateral chest radiographs are provided. There is no focal\n consolidation, pleural effusion, or pneumothorax. The cardiomediastinal\n silhouette is unremarkable. Median sternotomy wires are intact. Surgical\n clips are seen along the left heart border. There are degenerative changes\n throughout the thoracic spine and at the right acromioclavicular joint.",
"image_path": [
"p15/p15032623/s52019812/c1ca2269-888c6d31-99903c19-c02256b7-390f38a1.jpg"
],
"split": "test"
},
{
"id": "0e7807f6-04937b8e-ac237c79-1200da23-76b0b8e3",
"study_id": 57001920,
"subject_id": 14177219,
"report": "impression: 1. Stable mild cardiomegaly and stable pulmonary vascular engorgement.\n 2. No pneumonia or pulmonary edema. Findings: The lungs are clear. There is mild,\n stable cardiomegaly. There is no pneumothorax or pleural effusion. Mild\n pulmonary vascular engorgement is stable.",
"image_path": [
"p14/p14177219/s57001920/0e7807f6-04937b8e-ac237c79-1200da23-76b0b8e3.jpg"
],
"split": "test"
},
{
"id": "1d5931ea-ae06916c-5082d79e-ce203e51-6581ddc9",
"study_id": 53377112,
"subject_id": 18487334,
"report": "impression: 1. No radiographic evidence for acute cardiopulmonary process.\n 2. Possible delayed healing of the right 8th rib fracture. Correlation for\n pain at this location is recommended. Discussed with Dr. ___ by Dr.\n ___ by phone at 8:05 a.m. on ___. Findings: No focal consolidation, pleural effusion, or pneumothorax is seen. \n Heart size is top normal. Pacing leads appear to be similarly positioned\n compared to prior. There is no evidence for pulmonary edema. Multiple prior\n right rib fractures are seen; the 8th rib fracture demonstrates persist linear\n lucency, raising the possibility of incomplete healing. Sternal wires appear\n intact.",
"image_path": [
"p18/p18487334/s53377112/1d5931ea-ae06916c-5082d79e-ce203e51-6581ddc9.jpg"
],
"split": "test"
},
{
"id": "9aa3498d-70f8a9a5-132f5a2b-bb7c2837-2653ee2d",
"study_id": 58107496,
"subject_id": 13606683,
"report": "impression: Mildly indistinct pulmonary vascular markings suggestive of mild\n failure without frank pulmonary edema. Findings: PA and lateral views of the chest are compared to previous exams\n from ___ and ___.\n \n Linear opacities at the left greater than right base are suggestive of\n subsegmental atelectasis. Mildly indistinct pulmonary vascular markings are\n seen suggestive of mild failure; however, there is no definite confluent\n consolidation. Small left pleural effusion is seen. Cardiac silhouette is\n enlarged but stable. Again seen is a prosthetic valve. Median sternotomy\n wires are again seen with fracture at the inferior most wire. Osseous and\n soft tissue structures are otherwise unremarkable.",
"image_path": [
"p13/p13606683/s58107496/9aa3498d-70f8a9a5-132f5a2b-bb7c2837-2653ee2d.jpg"
],
"split": "test"
},
{
"id": "2501dbf9-714acd96-ca4fba08-e02967b8-23f99f37",
"study_id": 52488909,
"subject_id": 15259244,
"report": "There is little overall change. Again there is moderate pulmonary\n edema with probable bilateral effusions and substantial volume loss in the\n left lower lobe. In the appropriate clinical setting, superimposed pneumonia\n would have to be considered.",
"image_path": [
"p15/p15259244/s52488909/2501dbf9-714acd96-ca4fba08-e02967b8-23f99f37.jpg"
],
"split": "test"
},
{
"id": "2e3c3f7c-7193e986-db131763-296881f6-9c7d88d7",
"study_id": 54026146,
"subject_id": 16043637,
"report": "impression: No acute cardiopulmonary abnormality. Findings: A left pectoral pacemaker is unchanged in position with two leads\n terminating in the right atrium and right ventricle as before. The patient is\n status post median sternotomy and aortic valve repair with aortic valve\n prosthesis, unchanged in position and intact-appearing sternotomy wires. The\n cardiac silhouette and mediastinal contours are mildly increased in size in\n comparison to the most recent prior study likely attributable to slightly\n decreased lung volumes compared to the prior exam. The mediastinal and hilar\n contours are within normal limits. Hazy opacification of the bilateral lung\n bases is likely related to underpenetration of soft tissues on technique. \n There is no focal consolidation concerning for pneumonia, pleural effusion or\n pneumothorax. No overt pulmonary edema is present.",
"image_path": [
"p16/p16043637/s54026146/2e3c3f7c-7193e986-db131763-296881f6-9c7d88d7.jpg"
],
"split": "test"
},
{
"id": "4a6b6a7c-83ed2cdc-41c74d6e-ed8815a2-84ed02ff",
"study_id": 58773579,
"subject_id": 11540283,
"report": "impression: Mild cardiomegaly without superimposed acute cardiopulmonary process. Findings: The lungs are clear without focal consolidation, effusion, or edema. Left\n chest wall single lead pacing device is noted. Mild cardiomegaly is noted.\n Median sternotomy wires and mediastinal clips are seen. Prior endotracheal and\n enteric tubes are no longer visualized.",
"image_path": [
"p11/p11540283/s58773579/4a6b6a7c-83ed2cdc-41c74d6e-ed8815a2-84ed02ff.jpg"
],
"split": "test"
},
{
"id": "20d18a78-8f7cd753-628b5cf4-7d43c522-c3e8f53e",
"study_id": 56218099,
"subject_id": 12530259,
"report": "impression: No pneumothorax status post biopsy of known left hilar mass. Findings: Portable upright chest radiograph demonstrates a known left hilar\n mass. There is no effusion, or definite pneumothorax. The cardiac silhouette\n and mediastinal contours are otherwise unremarkable.",
"image_path": [
"p12/p12530259/s56218099/20d18a78-8f7cd753-628b5cf4-7d43c522-c3e8f53e.jpg"
],
"split": "test"
},
{
"id": "33afaafe-a1605f54-f33616de-424605bf-7c961442",
"study_id": 50416709,
"subject_id": 16848073,
"report": "impression: No acute cardiopulmonary process, pneumothorax, or\n pneumomediastinum. Findings: Lung volumes are mildly decreased. Blunting of the bilateral\n costophrenic angles has not changed since at least ___. Cardiac and\n mediastinal contours are normal. There is no evidence of pneumothorax or\n pneumomediastinum.",
"image_path": [
"p16/p16848073/s50416709/33afaafe-a1605f54-f33616de-424605bf-7c961442.jpg"
],
"split": "test"
},
{
"id": "2a41d909-c858a5fc-da024f8f-a33bd3ff-ed8fe748",
"study_id": 57088454,
"subject_id": 19499595,
"report": "Frontal and lateral views of the chest were obtained. No definite\n focal consolidation is seen. There is no pleural effusion or pneumothorax. \n The patient is status post median sternotomy with multiple fractured sternal\n wires including the third superior most and additional more inferior as also\n seen previously. Cardiac silhouette is mildly enlarged. There may be slight\n prominence of the main pulmonary artery, which may be in part related to\n patient positioning, however, underlying pulmonary hypertension is not\n excluded.",
"image_path": [
"p19/p19499595/s57088454/2a41d909-c858a5fc-da024f8f-a33bd3ff-ed8fe748.jpg"
],
"split": "test"
},
{
"id": "7a1a7ec8-c865adb3-011681d5-d61e27b1-6d31ab75",
"study_id": 50845269,
"subject_id": 11293517,
"report": "impression: Limited study demonstrating moderate cardiomegaly and no overt\n edema or pneumonia. Findings: AP upright and lateral views of the chest were provided. Left\n chest wall pacer pack is again seen with leads extending into the right heart.\n Abandoned pacing leads are also noted in the right chest wall extending into\n the right heart. The heart remains moderately enlarged. Lung volumes are\n low, with equivocal ground-glass opacity on the frontal view, which appears\n less conspicuous on the lateral view most likely attributable to\n underpenetrated technique. No gross evidence for pneumonia or pulmonary\n edema. No large effusions are seen. There is no pneumothorax. Bony\n structures are intact.",
"image_path": [
"p11/p11293517/s50845269/7a1a7ec8-c865adb3-011681d5-d61e27b1-6d31ab75.jpg"
],
"split": "test"
},
{
"id": "e043f870-1670fd0c-cf68f196-4f351347-4a665c39",
"study_id": 58071016,
"subject_id": 19075045,
"report": "impression: Worsened left basilar opacity, may represent atelectasis, consider pneumonitis\n in the appropriate clinical setting. Pulmonary vascularity has mildly\n improved. Findings: Sternotomy with valve prosthesis. Endotracheal tube tip is 4 cm above carina.\n Right IJ central line tip is near cavoatrial junction. Cardiac pacemaker. \n There is worsening of left basilar opacity. Left costophrenic angle is not\n fully seen. No pneumothorax. Shallow inspiration accentuates heart size,\n pulmonary vascularity. Pulmonary vascularity has mildly improved. Improved\n right basilar, perihilar opacities. Right shoulder arthroplasty.",
"image_path": [
"p19/p19075045/s58071016/e043f870-1670fd0c-cf68f196-4f351347-4a665c39.jpg"
],
"split": "test"
},
{
"id": "7794e4cb-719a0b85-18532575-0b5ea119-8eb26b6a",
"study_id": 54028344,
"subject_id": 13475033,
"report": "impression: 1. No acute cardiopulmonary process.\n \n 2. Stable mild cardiomegaly.\n \n 3. Unchanged proximal tracheal deformity suggestive of underlying\n tracheomalacia. Findings: A large-bore central catheter terminates in\n the expected location of the right atrium, unchanged from prior. The lungs\n are clear. There is no focal consolidation or pneumothorax. There is no\n vascular congestion or pleural effusions. Mediastinal and hilar contours are\n within normal limits. The cardiac silhouette is mildly enlarged though\n unchanged. Mild indentation of the left trachea at the level of the clavicles\n is unchanged compared to prior chest CT from ___ and likely reflects an\n underlying tracheal deformity as no compressive mass lesion is evident on the\n prior CT.",
"image_path": [
"p13/p13475033/s54028344/7794e4cb-719a0b85-18532575-0b5ea119-8eb26b6a.jpg"
],
"split": "test"
},
{
"id": "7b9c311b-b511e83b-75a5a6cf-d46efb9d-ac034314",
"study_id": 55086195,
"subject_id": 19028690,
"report": "impression: Mild interstial edema. Findings: The patient is slightly rotated. The\n heart size is normal. The hilar and mediastinal contours are within normal\n limits. There has been interval increase in central pulmonary vessel\n prominence and interstial opacities, representing mild edema. Increased linear\n atelectasis at the left base is seen. There is no pneumothorax or large\n pleural effusion. No free intrabdominal air is detected on this upright study.",
"image_path": [
"p19/p19028690/s55086195/7b9c311b-b511e83b-75a5a6cf-d46efb9d-ac034314.jpg"
],
"split": "test"
},
{
"id": "67653b61-d4cdc144-670c5d2f-1d19f3a2-480d85a1",
"study_id": 52152296,
"subject_id": 11934114,
"report": "impression: Moderate right pleural effusion with adjacent lung atelectasis\n has improved since ___. Findings: Right PICC line ends at low SVC. Moderate right pleural effusion with\n adjacent lung atelectasis has decreased since ___. Minimal left\n pleural effusion is unchanged. There are no new lung opacities of concern for\n pneumonia. Heart size, mediastinal and hilar contours are stable.",
"image_path": [
"p11/p11934114/s52152296/67653b61-d4cdc144-670c5d2f-1d19f3a2-480d85a1.jpg"
],
"split": "test"
},
{
"id": "d8b6b619-9e181de2-c46adb2d-08194ead-eefd7108",
"study_id": 56277244,
"subject_id": 15857729,
"report": "impression: Pneumonia involving the medial segment of the right middle lobe. Findings: PA and lateral views of the chest were obtained. There is right\n middle lobe consolidation involving the medial segment. Otherwise, the lungs\n are clear. No large pleural effusion or pneumothorax. Cardiomediastinal\n silhouette appears normal. Bony structures are intact. No free air below the\n right hemidiaphragm.",
"image_path": [
"p15/p15857729/s56277244/d8b6b619-9e181de2-c46adb2d-08194ead-eefd7108.jpg"
],
"split": "test"
},
{
"id": "be142141-0e637201-65d2ff88-43edd072-198d4dc7",
"study_id": 52269494,
"subject_id": 19907884,
"report": "Frontal and lateral views of the chest were obtained. There are\n low lung volumes and bronchovascular crowding. There is prominence of the\n hila suggesting pulmonary vascular engorgement with possible mild pulmonary\n vascular congestion. No pleural effusion or pneumothorax is seen. Left\n infrahilar and left basilar opacity may relate to vascular crowding, although\n infectious process cannot be excluded in the appropriate clinical setting. \n There are right paramediastinal surgical clips. Cardiac and mediastinal\n silhouettes are stable.",
"image_path": [
"p19/p19907884/s52269494/be142141-0e637201-65d2ff88-43edd072-198d4dc7.jpg"
],
"split": "test"
},
{
"id": "cf215d80-de177339-7a58b114-8206a52d-f9b1fc56",
"study_id": 54050506,
"subject_id": 13473495,
"report": "impression: Stable mild pulmonary edema and moderate cardiomegaly. Bibasilar opacities\n may represent atelectasis or infection in the appropriate clinical setting. Findings: Frontal and lateral views of the chest were slightly limited due to patient's\n body habitus. Lung volumes are low, which accentuate bronchovascular\n markings. Mild pulmonary edema is unchanged. There is mild thickening of the\n minor fissure. Bibasilar opacities are noted. There is no pleural effusion. \n Moderate cardiomegaly is stable. Hilar and mediastinal silhouettes are\n unchanged. A dual-chamber dialysis catheter tip projects over proximal right\n atrium.",
"image_path": [
"p13/p13473495/s54050506/cf215d80-de177339-7a58b114-8206a52d-f9b1fc56.jpg"
],
"split": "test"
},
{
"id": "13c8c746-5d1d71f5-af021e53-041a96c3-710e3730",
"study_id": 57667222,
"subject_id": 17897339,
"report": "impression: Left basilar atelectasis. No consolidation, edema or pleural\n effusions. Findings: Left basilar opacities likely represent\n subsegmental atelectasis. The lung volumes are low but otherwise clear. \n There is no pneumothorax. No vascular congestion or large pleural effusions\n are evident. Cardiomediastinal and hilar contours are within normal limits. \n The colon is distended below the left hemidiaphragm.",
"image_path": [
"p17/p17897339/s57667222/13c8c746-5d1d71f5-af021e53-041a96c3-710e3730.jpg"
],
"split": "test"
},
{
"id": "14047a00-16ef4559-fd349a7f-fc7d9ef5-2667ceaf",
"study_id": 57955448,
"subject_id": 16751749,
"report": "impression: Status post intubation with tip 6 cm above carina. No\n pneumothorax. Relative opacity at lateral right lung base thought to\n represent scarring versus infectious process on prior study is better\n evaluated on current study and appears to be consistent with scarring,\n unchanged from ___. Findings: Portable chest radiograph demonstrates interval placement of\n endotracheal tube with tip 6 cm above the carina. Nasogastric tube seen\n coursing into the stomach and out of view. No pneumothorax identified. \n Otherwise, unchanged exam with hyperinflation of lungs and severe bullous\n emphysematous changes identified in the upper lungs, particularly on the left.\n Increased opacity at the lateral right lung base thought to represent scarring\n versus infectious process on prior study is better evaluated on current study\n and appears to be consistent with scarring, unchanged from ___. No\n pleural effusions evident.",
"image_path": [
"p16/p16751749/s57955448/14047a00-16ef4559-fd349a7f-fc7d9ef5-2667ceaf.jpg"
],
"split": "test"
},
{
"id": "4f7d591a-e6d9f7a8-05c5e886-421a776a-66a7a9eb",
"study_id": 54351633,
"subject_id": 11204646,
"report": "As compared to the previous radiograph, the previously visible\n right internal jugular vein catheter has been removed. The patient is still\n intubated, with an unchanged position of the endotracheal tube, nasogastric\n tube and the right PICC line. Unchanged moderate cardiomegaly. Unchanged\n mild-to-moderate right pleural effusion, unchanged mild fluid overload and\n areas of moderate retrocardiac atelectasis. There is no newly occurred focal\n parenchymal opacity.",
"image_path": [
"p11/p11204646/s54351633/4f7d591a-e6d9f7a8-05c5e886-421a776a-66a7a9eb.jpg"
],
"split": "test"
},
{
"id": "486dfea4-dc27bc78-a4e9effa-c328c0ab-a8c3285e",
"study_id": 52971146,
"subject_id": 17770657,
"report": "Single portable chest radiograph demonstrates Dobbhoff tube coiled\n within the stomach with tip terminating within the mid esophagus. Exam is\n otherwise unchanged.\n \n ___ discussed these findings (including those of the 2 prior\n radiographs) with ___, PA, at 16:15 on ___ at the time\n of discovery who reports the third and final radiograph demonstrated a\n well-positioned Dobbhoff tube.",
"image_path": [
"p17/p17770657/s52971146/486dfea4-dc27bc78-a4e9effa-c328c0ab-a8c3285e.jpg"
],
"split": "test"
},
{
"id": "ae0ca9f1-a6aa65c0-b8754692-be29d5b4-8ce0e6ff",
"study_id": 51866834,
"subject_id": 11204646,
"report": "Comparison is made to previous study from ___.\n \n The endotracheal tube and right-sided IJ central venous line are unchanged in\n position and appropriately sited. There is also a left-sided subclavian\n catheter with distal lead tip in the proximal SVC. There is stable\n cardiomegaly. There are again seen bilateral pleural effusions and a left\n retrocardiac opacity. There are no signs for overt pulmonary edema. There\n are no pneumothoraces.",
"image_path": [
"p11/p11204646/s51866834/ae0ca9f1-a6aa65c0-b8754692-be29d5b4-8ce0e6ff.jpg"
],
"split": "test"
},
{
"id": "58c735ba-cc7d2492-f290f622-154bc6f2-5fdc853c",
"study_id": 50501762,
"subject_id": 10439781,
"report": "impression: New pulmonary parenchymal abnormalities on top of chronic pulmonary fibrosis\n most likely represents pulmonary edema. Infection is less likely. Findings: AP upright and lateral chest radiographs were obtained. Known interstitial\n lung disease contributes to a bilateral perihilar interstitial abnormality. \n In addition to the chronic findings there is bilateral ground-glass opacity\n and interstitial thickening, predominantly radiating from the hila. \n Cardiomegaly remains moderate. Aortic arch calcifications are unchanged. A\n right-sided PICC line terminates in the low SVC. A left chest Port-A-Cath\n terminates in the right atrium. Vertebroplasty changes are stable.",
"image_path": [
"p10/p10439781/s50501762/58c735ba-cc7d2492-f290f622-154bc6f2-5fdc853c.jpg"
],
"split": "test"
},
{
"id": "081b6db8-da3b5047-573fbc16-9aa955fa-d35d3cc2",
"study_id": 50994417,
"subject_id": 15438386,
"report": "AP and lateral chest radiographs demonstrate very low lung volumes\n and probable bibasilar opacities, likely atelectasis, though consolidation\n cannot be excluded. Bilateral small pleural effusions are also present. The\n cardiomediastinal silhouette appears widened due to low lung volumes. There\n is no pneumothorax. Old right mid clavicular fracture is noted.",
"image_path": [
"p15/p15438386/s50994417/081b6db8-da3b5047-573fbc16-9aa955fa-d35d3cc2.jpg"
],
"split": "test"
},
{
"id": "3622b493-4fc54d50-37c8dd39-9ad4b433-1fc9ab20",
"study_id": 58084420,
"subject_id": 16773796,
"report": "impression: Left lower lobe pneumonia. Findings: Sternotomy wires and mediastinal clips are unchanged as is the\n prosthetic aortic valve. The heart size is within normal limits. The\n mediastinal contours appear unremarkable. There continues to be opacity\n projecting over the heart on the frontal view with air bronchograms which\n correlates with increased opacity in the retrocardiac space. There is no\n pneumothorax.",
"image_path": [
"p16/p16773796/s58084420/3622b493-4fc54d50-37c8dd39-9ad4b433-1fc9ab20.jpg"
],
"split": "test"
},
{
"id": "989b6a15-ba84ab43-d60ebb5a-c7681741-c34f140f",
"study_id": 55878458,
"subject_id": 10715477,
"report": "New PICC line on the right is projecting with its tip somewhere in\n the mediastinum. Appears to cross the midline, there is concern for potential\n arterial location. The initial line concerns were communicated over the\n telephone at the time of the wet read. Repeat PA and lateral radiograph,\n taken approximately an hour after the radiograph demonstrated the PICC line in\n the mid SVC. Potential small right pleural effusion. Stable moderate\n cardiomegaly.",
"image_path": [
"p10/p10715477/s55878458/989b6a15-ba84ab43-d60ebb5a-c7681741-c34f140f.jpg"
],
"split": "test"
},
{
"id": "de140675-ed4e6db5-111e6c9c-427ebbe7-7e83e354",
"study_id": 52056700,
"subject_id": 18929056,
"report": "As compared to the previous radiograph, the known right lower lobe\n pneumonia is minimally more extensive on today's image. There could be an\n associated minimal right pleural effusion. No abnormalities in the left lung.\n Persistent overinflation and resulting large lung volumes. Moderate\n cardiomegaly with tortuosity of the thoracic aorta. Unchanged left pectoral\n pacemaker.",
"image_path": [
"p18/p18929056/s52056700/de140675-ed4e6db5-111e6c9c-427ebbe7-7e83e354.jpg"
],
"split": "test"
},
{
"id": "eae82e15-d009faf9-ea670371-7404ef86-edfc3065",
"study_id": 57976054,
"subject_id": 16409152,
"report": "One portable supine view of the chest. The endotracheal tube ends\n in the right internal jugular line and is in unchanged position. No NG tube\n is seen. The lung findings are unchanged compared to 45 minutes earlier.",
"image_path": [
"p16/p16409152/s57976054/eae82e15-d009faf9-ea670371-7404ef86-edfc3065.jpg"
],
"split": "test"
},
{
"id": "b03d121a-8a657f7b-2c3da5f3-6828c27c-2a4d38a4",
"study_id": 56241369,
"subject_id": 16360107,
"report": "impression: Stable chronic abnormalities including bilateral moderate loculated pleural\n effusions and areas of round atelectasis. Findings: The cardiac, mediastinal and hilar contours appear stable. Deshiscences among\n sternal wires appear unchanged. Moderate bilateral pleural effusions appear\n stable a and seem to be due to chronic collections which were also\n characterized on prior CT with associated round atelectasis especially at the\n right lung base. There has been little if any change. Although there is no\n evidence of acute process should be noted that background abnormalities may\n lower the sensitivity of chest radiography.",
"image_path": [
"p16/p16360107/s56241369/b03d121a-8a657f7b-2c3da5f3-6828c27c-2a4d38a4.jpg"
],
"split": "test"
},
{
"id": "d6326d09-908b90e7-7f3c10fc-620713fc-4e490c4a",
"study_id": 50324889,
"subject_id": 14744884,
"report": "impression: Mild to moderate pulmonary edema, slightly worse in the interval with trace\n right pleural effusion and bibasilar atelectasis. Findings: Heart size remains mild to moderately enlarged. The mediastinal contour is\n unchanged. A a right subclavian vein stent appears unchanged. Mild to moderate\n pulmonary edema is worse in the interval. Patchy opacities in the lung bases\n likely reflect areas of atelectasis. Minimal right pleural effusion is noted.\n No pneumothorax is identified. Nodes osseous abnormalities detected.",
"image_path": [
"p14/p14744884/s50324889/d6326d09-908b90e7-7f3c10fc-620713fc-4e490c4a.jpg"
],
"split": "test"
},
{
"id": "ceb97930-fe5ec7d6-6ee4c8aa-56e46341-d0fbfd43",
"study_id": 53012323,
"subject_id": 18343726,
"report": "impression: Resolved left lower lobe pneumonia. No new acute cardiopulmonary\n process. Findings: The previously seen left lower lobe opacity has resolved. There is\n no new focal consolidation, pleural effusion, or pneumothorax. The\n cardiomediastinal silhouette is normal. There are no acute bony findings.",
"image_path": [
"p18/p18343726/s53012323/ceb97930-fe5ec7d6-6ee4c8aa-56e46341-d0fbfd43.jpg"
],
"split": "test"
},
{
"id": "c2f49f11-42bbe227-0e97f6b4-10ea93f4-e05ef9fb",
"study_id": 50818829,
"subject_id": 16508811,
"report": "impression: Bibasilar airspace opacities are increasing and are likely related to\n worsening pulmonary edema and atelectasis. Findings: A left-sided internal jugular catheter is stable in position. A right-sided\n internal jugular dialysis catheter is also stable. There is no pneumothorax. \n Bibasilar pulmonary opacities are increasing from the prior examination done\n yesterday and are likely related to increasing pulmonary edema and\n atelectasis.",
"image_path": [
"p16/p16508811/s50818829/c2f49f11-42bbe227-0e97f6b4-10ea93f4-e05ef9fb.jpg"
],
"split": "test"
},
{
"id": "c1f8ae0f-24d9f65f-2a25b45f-75887445-8974af9c",
"study_id": 52971492,
"subject_id": 13023326,
"report": "impression: Successful thoracocentesis removing major portion of left-sided\n pleural effusion. No pneumothorax following thoracocentesis. Findings: PA and lateral chest views were obtained with patient in upright\n position. Analysis is performed in direct comparison with the next preceding\n PA and lateral chest examination of ___. Whereas the described\n changes in the right hemithorax are stable, the left-sided basal pleural\n density has decreased markedly and the left-sided diaphragmatic contour is now\n identified both on frontal and lateral view. No evidence of pneumothorax in\n the apical areas on either side.",
"image_path": [
"p13/p13023326/s52971492/c1f8ae0f-24d9f65f-2a25b45f-75887445-8974af9c.jpg"
],
"split": "test"
},
{
"id": "d1476c64-942c69d1-01468aa0-5ba156c1-07f5abb4",
"study_id": 59071382,
"subject_id": 10867202,
"report": "impression: Multifocal opacities worrisome for pneumonia superimposed on\n severe underlying interstitial lung disease; although recent prior radiographs\n are not available for comparison and progression of chronic lung disease could\n be considered as an alternative, acute superimposed pneumonia seems most\n likely. Findings: In the background of severe interstitial lung disease, which is\n predominantly reflected in fine reticulation of the lung periphery on each\n side, there are patchy superimposed opacities in the right upper lung as well\n as the left mid and lower lung worrisome for superimposed pneumonia. There is\n no pleural effusion or pneumothorax. The lung volume are again low. The\n cardiac, mediastinal and hilar contours appear unchanged, allowing for\n differences in technique.",
"image_path": [
"p10/p10867202/s59071382/d1476c64-942c69d1-01468aa0-5ba156c1-07f5abb4.jpg"
],
"split": "test"
},
{
"id": "404c92ca-507a2663-933cb795-d5538049-f6ed552e",
"study_id": 51889790,
"subject_id": 19182863,
"report": "impression: Persistent successful status post right-sided thoracocentesis,\n mildly increasing pulmonary congestive pattern with perivascular haze. \n Diagnosis of left-sided pneumonic infiltrate is questionable unless compelling\n clinical findings are present. Findings: AP single view of the chest has been obtained with patient in\n semi-upright position. Analysis is performed in direct comparison with the\n next preceding similar study of ___. Status post thoracotomy, moderate\n cardiac enlargement and evidence of aortic valve prosthesis as well as\n tricuspid valve annuloplasty as before. The removal of the right-sided\n pleural effusion of the preceding day remains successful as the right-sided\n diaphragmatic contour and pleural sinus is free, demonstrating the pigtail-end\n catheter in unchanged position. No pneumothorax has developed. The pulmonary\n vascular pattern again demonstrates perivascular haze throughout which in\n comparison appears slightly increased again. This may have led to question a\n left-sided pneumonia, a diagnosis which is questionable.",
"image_path": [
"p19/p19182863/s51889790/404c92ca-507a2663-933cb795-d5538049-f6ed552e.jpg"
],
"split": "test"
},
{
"id": "a6aad5da-2b346586-e6b4b977-d71b3973-925a1eb1",
"study_id": 52412265,
"subject_id": 13473495,
"report": "impression: 1. Opacity at left costophrenic angle likely reflects atelectasis vs. pleural\n fluid.\n \n 2. Pulmonary edema. Findings: Redemonstration of moderate-to-severe cardiomegaly is noted. There is\n pulmonary vascular congestion consistent with edema. There is vague increased\n opacity at the left costophrenic angle which may reflect atelectasis versus a\n small pleural effusion. Redemonstration of a left subclavian venous stent is\n again noted. There is no evidence of pneumoperitoneum. Osseous structures\n are unchanged.",
"image_path": [
"p13/p13473495/s52412265/a6aad5da-2b346586-e6b4b977-d71b3973-925a1eb1.jpg"
],
"split": "test"
},
{
"id": "f9d601d7-0eb2306d-2e66934e-5db0f766-edb49564",
"study_id": 54907683,
"subject_id": 16015751,
"report": "impression: 1. No acute cardiopulmonary process.\n 2. 9-mm right lower lobe nodule. As per the patient's CT ___,\n the patient is due to have a followup chest CT to assess right lower lobe\n nodule, to reassess right lower lung nodule. Findings: A right lower lobe nodule is similar in appearance to prior\n radiograph and CT, however true volume cannot be measured on radiography. \n Otherwise, the lungs are clear. There is no additional nodule, consolidation,\n effusion, or pneumothorax. The heart and mediastinal contours are normal. \n There is mild tortuosity of the descending aorta. Osseous structures are\n unremarkable.",
"image_path": [
"p16/p16015751/s54907683/f9d601d7-0eb2306d-2e66934e-5db0f766-edb49564.jpg"
],
"split": "test"
},
{
"id": "46c161c4-0cac1236-ec95dd28-d99eb016-ee9a344d",
"study_id": 59698726,
"subject_id": 15857729,
"report": "impression: No acute cardiopulmonary process. Findings: PA and lateral views of the chest pain. The lungs are clear. \n Cardiomediastinal silhouette is normal. No acute osseous abnormalities\n detected. Stent is identified in the upper abdomen.",
"image_path": [
"p15/p15857729/s59698726/46c161c4-0cac1236-ec95dd28-d99eb016-ee9a344d.jpg"
],
"split": "test"
},
{
"id": "e01e8de2-d5095cb4-f851985e-df9c203c-89326fdb",
"study_id": 58833368,
"subject_id": 15131736,
"report": "impression: 1. ET tube in good location.\n \n 2. Increased CHF. An underlying infectious infiltrate cannot be excluded Findings: There is a new ET tube 5.4 cm above the carina. There is pulmonary vascular\n redistribution that is worsened in the interval with alveolar infiltrates\n bilaterally and dense retrocardiac opacity that could be due to volume\n loss/infiltrate/effusion. The heart size is moderately enlarged. NG tube tip\n is in the stomach. There is a small right effusion.",
"image_path": [
"p15/p15131736/s58833368/e01e8de2-d5095cb4-f851985e-df9c203c-89326fdb.jpg"
],
"split": "test"
},
{
"id": "5e587c3b-2593ff0d-f7ac821e-4955e532-83ba9419",
"study_id": 57739082,
"subject_id": 16853729,
"report": "impression: Moderate cardiomegaly. Mild pulmonary vascular congestion, but\n no overt edema. Findings: AP and lateral views of the chest. Moderate cardiomegaly is\n stable. Widened mediastinum with tortuous aorta is unchanged. There is mild\n pulmonary vascular congestion, but no overt edema. No focal consolidation\n identified. No pneumothorax.",
"image_path": [
"p16/p16853729/s57739082/5e587c3b-2593ff0d-f7ac821e-4955e532-83ba9419.jpg"
],
"split": "test"
},
{
"id": "a839e43c-1d7f9788-1f4d11ef-8bf9c279-74ebcc3f",
"study_id": 54507407,
"subject_id": 19623993,
"report": "impression: No acute cardiopulmonary process. Improved pulmonary vascular\n engorgement since ___. Findings: The inspiratory lung volumes are appropriate. There is improved\n pulmonary vascular engorgement since the prior study of ___ and no\n pulmonary edema. The lungs are clear without pleural effusion, focal\n consolidation or pneumothorax. The cardiac silhouette is normal in size. The\n mediastinal and hilar contours are unchanged with persistent prominence of the\n azygos vein.",
"image_path": [
"p19/p19623993/s54507407/a839e43c-1d7f9788-1f4d11ef-8bf9c279-74ebcc3f.jpg"
],
"split": "test"
},
{
"id": "783fc94d-12b747b1-600f2e10-c1c51d2a-97240f95",
"study_id": 53352013,
"subject_id": 12124741,
"report": "impression: No acute findings in the chest. Findings: PA and lateral views of the chest provided. Midline sternotomy\n wires and mediastinal clips are again noted. The previously noted Port-A-Cath\n has been removed. The lungs are clear bilaterally without focal\n consolidation, effusion, or pneumothorax. Cardiomediastinal silhouette is\n stable. Bony structures are intact. No free air below the right\n hemidiaphragm is seen.",
"image_path": [
"p12/p12124741/s53352013/783fc94d-12b747b1-600f2e10-c1c51d2a-97240f95.jpg"
],
"split": "test"
},
{
"id": "099dc924-692466a3-cd889469-1d9dee6c-3a61f779",
"study_id": 59438963,
"subject_id": 14236258,
"report": "impression: No acute cardiopulmonary process. Findings: When compared to prior, there has been no significant interval change. Lungs\n are grossly clear. There is no large effusion or edema. Cardiomediastinal\n silhouette is within normal limits. Rightward deviation of the trachea at the\n thoracic inlet is compatible with known underlying left-sided thyroid\n enlargement. Surgical clips seen projecting over the thoracic inlet. Left\n chest wall dual lumen central venous catheter is now seen. Multiple vascular\n stents project over the left upper extremity and mediastinum. Severe\n degenerative changes noted at the shoulders bilaterally. Old healed right\n posterior rib fractures are also noted.",
"image_path": [
"p14/p14236258/s59438963/099dc924-692466a3-cd889469-1d9dee6c-3a61f779.jpg"
],
"split": "test"
},
{
"id": "7c41a809-f93b8fdb-32b0f64f-3c464002-d1751a7c",
"study_id": 55011437,
"subject_id": 14504940,
"report": "impression: Normal contour of the mediastinum without evidence of widening. \n Streaky opacities in the lung bases likely reflect atelectasis. Findings: The patient is status post median sternotomy\n and CABG. The cardiac, mediastinal, and hilar contours are normal. The\n pulmonary vascularity is normal. There are streaky opacities in the lung\n bases, most likely reflective of atelectasis. No focal consolidation, pleural\n effusion, or pneumothorax is visualized. There are no acute osseous\n abnormalities.",
"image_path": [
"p14/p14504940/s55011437/7c41a809-f93b8fdb-32b0f64f-3c464002-d1751a7c.jpg"
],
"split": "test"
},
{
"id": "159f8b16-a8da78c3-2dab8f92-5577b199-2d544ffc",
"study_id": 57697281,
"subject_id": 13120957,
"report": "impression: No acute cardiopulmonary process. Findings: Lungs are clear. There is no consolidation, effusion, or edema. The\n cardiomediastinal silhouette is within normal limits. No acute osseous\n abnormalities.",
"image_path": [
"p13/p13120957/s57697281/159f8b16-a8da78c3-2dab8f92-5577b199-2d544ffc.jpg"
],
"split": "test"
},
{
"id": "9c04078c-dee8c858-bc2a105e-d5fb538e-ac5a7c69",
"study_id": 59047668,
"subject_id": 18417750,
"report": "impression: Cardiomegaly without signs of failure or edema. Other findings\n as described above. Findings: AP upright and lateral views of the chest are provided. Dual-lead\n pacemaker is in unchanged position. A metallic stent projects over the heart\n in the expected location of the aortic valve. Hardware is noted in the lower\n thoracic spine with evidence of vertebroplasty in a lower thoracic vertebral\n body. Cardiomegaly is unchanged. There is no definite sign of pulmonary\n edema. No pleural effusion or signs of pneumonia. Mediastinal contour is\n stable. Bony structures appear unchanged. A wedge deformity is seen just\n above the level of vertebroplasty in the lower T-spine which is unchanged.",
"image_path": [
"p18/p18417750/s59047668/9c04078c-dee8c858-bc2a105e-d5fb538e-ac5a7c69.jpg"
],
"split": "test"
},
{
"id": "7a448024-34b46da3-0662ce39-3a69ebb7-30625b25",
"study_id": 50706776,
"subject_id": 16508811,
"report": "impression: Moderate pulmonary vascular congestion. Bibasilar opacities are felt to more\n likely relate to vascular congestion rather than consolidation, however in the\n appropriate clinical setting, underlying pneumonia is difficult to exclude. Findings: Large-bore right-sided central venous catheter is stable in position,\n terminating and the proximal right atrium. The cardiac and mediastinal\n silhouettes are stable. There is moderate pulmonary vascular congestion. \n Bibasilar opacities are felt to more likely relate to vascular congestion\n rather than consolidation, however in the appropriate clinical setting,\n underlying pneumonia is difficult to exclude. No pleural effusion or\n pneumothorax is seen.",
"image_path": [
"p16/p16508811/s50706776/7a448024-34b46da3-0662ce39-3a69ebb7-30625b25.jpg"
],
"split": "test"
},
{
"id": "b9d3a2a8-efad6e43-fd5c9461-389ea619-4454f98c",
"study_id": 58936592,
"subject_id": 17838301,
"report": "impression: Findings consistent with mild pulmonary edema. Findings: The heart is moderately enlarged. The mediastinal and hilar\n contours appear unchanged, allowing for differences in technique. A band-like\n opacity projecting over the left mid lung suggests minor atelectasis or\n scarring. More generally, there is mild increased opacification with\n indistinct pulmonary vascularity suggesting mild pulmonary vascular congestion\n without definite focal opacities. Calcified pleural plaques are suspected.",
"image_path": [
"p17/p17838301/s58936592/b9d3a2a8-efad6e43-fd5c9461-389ea619-4454f98c.jpg"
],
"split": "test"
},
{
"id": "1fbd1640-367c4f70-02a3a28c-d27a8a1f-ac0fd964",
"study_id": 58495524,
"subject_id": 13475033,
"report": "impression: No acute cardiopulmonary process. Persistent increased\n interstitial markings in the lungs compatible with chronic interstitial\n disease. Interval resolution of the right mid lung opacity since prior. Findings: Single portable view of the chest is compared to previous exam from\n ___. Dual-lumen right subclavian central line is again seen with\n tip at the RA-SVC junction. Increased interstitial markings seen throughout\n the lungs are again noted and suggestive of chronic interstitial disease. \n Right mid lung opacity has resolved. The cardiomediastinal silhouette is\n stable as are the osseous and soft tissue structures.",
"image_path": [
"p13/p13475033/s58495524/1fbd1640-367c4f70-02a3a28c-d27a8a1f-ac0fd964.jpg"
],
"split": "test"
},
{
"id": "c2af2ab3-6a11cbae-d9fa4d64-21ab221e-cf6f2146",
"study_id": 50241018,
"subject_id": 11924226,
"report": "impression: Normal chest radiograph. No pleural effusion or pneumonia. Findings: Well expanded and clear lungs. No pleural effusion or pneumothorax. Heart\n size, mediastinal contour, and hila are within normal limits.\n \n Visualized upper abdomen is unremarkable.",
"image_path": [
"p11/p11924226/s50241018/c2af2ab3-6a11cbae-d9fa4d64-21ab221e-cf6f2146.jpg"
],
"split": "test"
},
{
"id": "4ffa9df0-24b7231c-3f67bde1-d9698406-f27658a3",
"study_id": 51229977,
"subject_id": 15131736,
"report": "impression: Pulmonary vascular congestion with persistent enlargement of the\n cardiac silhouette. No large pleural effusion is seen, although a small left\n pleural effusion would be difficult to exclude. Findings: Single AP upright portable view of the chest was obtained. There\n are relatively low lung volumes. Mild elevation of the right hemidiaphragm is\n unchanged. There has been interval removal of endotracheal and nasogastric\n tubes. There is pulmonary vascular congestion. No large pleural effusions\n are seen, although a trace effusion on the left would be difficult to exclude.\n No pneumothorax is seen. The cardiac silhouette remains enlarged.",
"image_path": [
"p15/p15131736/s51229977/4ffa9df0-24b7231c-3f67bde1-d9698406-f27658a3.jpg"
],
"split": "test"
},
{
"id": "93b9fbec-d0096ef4-0f25a638-a44849a5-58844ba5",
"study_id": 55410841,
"subject_id": 15378103,
"report": "As compared to the previous radiograph, the lung volumes have\n slightly decreased, which could potentially be caused by decreased ventilatory\n pressures. As a consequence, the bilateral parenchymal opacities appear\n slightly denser than on the previous image. The size of the cardiac\n silhouette is unchanged. No new parenchymal opacities have newly occurred. \n No pleural effusions are seen. The monitoring and support devices are\n constant.",
"image_path": [
"p15/p15378103/s55410841/93b9fbec-d0096ef4-0f25a638-a44849a5-58844ba5.jpg"
],
"split": "test"
},
{
"id": "79efe8cb-356ec1b4-23153a48-35b3a64c-40e70a3a",
"study_id": 54058678,
"subject_id": 15446959,
"report": "There is little change in comparison to prior study. Post-surgical\n changes are again noted including en bloc resection of the sixth through tenth\n ribs. Mesh reconstruction along the left chest wall is again noted. Fibrosis\n is noted in the left lateral lung zone. Cardiomediastinal silhouette is\n stable with the heart size at top normal. Otherwise, the lungs are clear with\n no evidence of consolidation, effusion, or pneumothorax. Multilevel\n degenerative changes are again visualized.",
"image_path": [
"p15/p15446959/s54058678/79efe8cb-356ec1b4-23153a48-35b3a64c-40e70a3a.jpg"
],
"split": "test"
},
{
"id": "fd480467-a520cdee-c10d86b1-219b21f7-64bb593d",
"study_id": 55743226,
"subject_id": 11378150,
"report": "impression: No pneumothorax. Large left lower lobe mass, better evaluated on\n prior CT. Findings: Single portable chest radiograph demonstrates a large rounded\n opacity in the left lower lung, correlating with known left lung mass, better\n visualized on the ___ PET-CT. No focal opacification concerning\n for pneumonia. Bibasilar atelectasis is evident. Coarse linear interstitial\n markings in left upper lobe may reflect emphysematous change. There is no\n pneumothorax or pleural effusion. Prominent pericardial fat pads are evident;\n otherwise, cardiomediastinal contours are normal.",
"image_path": [
"p11/p11378150/s55743226/fd480467-a520cdee-c10d86b1-219b21f7-64bb593d.jpg"
],
"split": "test"
},
{
"id": "dfd7957a-264424c1-2d9c4a61-2b5aa381-f6983154",
"study_id": 54135185,
"subject_id": 14608347,
"report": "impression: 1. Stable moderate hiatal hernia.\n 2. No acute cardiopulmonary process. No evidence of aspiration. Findings: Air-fluid levels are identified within the\n previously visualized retrocardiac opacity, findings consistent with a stable\n moderate hiatal hernia. The lungs are clear. There is no focal consolidation\n or pneumothorax. There is no vascular congestion or pleural effusions. \n Cardiomediastinal and hilar contours are within normal limits.",
"image_path": [
"p14/p14608347/s54135185/dfd7957a-264424c1-2d9c4a61-2b5aa381-f6983154.jpg"
],
"split": "test"
},
{
"id": "bdd612ef-c670dd82-8e5b97e4-82d8c071-20405c37",
"study_id": 55400628,
"subject_id": 14236258,
"report": "impression: Right basilar opacity is stable as compared to the prior study\n from ___. No large pleural effusion. Possible mild vascular\n congestion. Findings: Frontal and lateral views of the chest were obtained. A vascular\n stent is again noted in the left brachiocephalic vein and SVC, stable in\n position. The cardiac and mediastinal silhouettes are stable. Prominence of\n the right hilum is grossly stable. Subtle prominence of perihilar vasculature\n may be due to mild vascular congestion. The right basilar opacity is stable\n as compared to the prior study from ___.",
"image_path": [
"p14/p14236258/s55400628/bdd612ef-c670dd82-8e5b97e4-82d8c071-20405c37.jpg"
],
"split": "test"
},
{
"id": "1f7d224a-19e6cfa7-5627f007-83212a22-be1faf67",
"study_id": 57681546,
"subject_id": 15378103,
"report": "As compared to the previous radiograph, the right and left pleural\n effusions are virtually unchanged. They are mild-to-moderate in extent. The\n effusions are at the source of bilateral areas of compression atelectasis.\n \n Unchanged borderline size of the cardiac silhouette. No evidence of\n pneumonia. Unchanged right internal jugular vein catheter and left pectoral\n pacemaker.\n \n No pneumothorax.",
"image_path": [
"p15/p15378103/s57681546/1f7d224a-19e6cfa7-5627f007-83212a22-be1faf67.jpg"
],
"split": "test"
},
{
"id": "09bcae55-47d8afaa-5cd21ca4-2cc83c46-d432bd6d",
"study_id": 50879902,
"subject_id": 10402372,
"report": "As compared to the previous radiograph, there is a subtle but new\n opacity at the right lung base, in the medial aspect of the lung. The\n opacities located in an area of bronchiectasis. Given the clinical\n presentation, pneumonia must be suspected. The referring physician, ___. ___\n was paged for notification at the time of dictation, 3:18 p.m. on ___ and the findings were discussed over the telephone.\n \n Otherwise, the radiograph is unchanged, extensive overinflation with\n bronchiectasis but no pleural effusions or other parenchymal changes. Normal\n size of the cardiac silhouette. Unchanged position of the nasogastric tube.",
"image_path": [
"p10/p10402372/s50879902/09bcae55-47d8afaa-5cd21ca4-2cc83c46-d432bd6d.jpg"
],
"split": "test"
},
{
"id": "b00146a8-daf7d7b9-b5b42300-46be81dc-b7c723c0",
"study_id": 50476602,
"subject_id": 16875792,
"report": "AP single view of the chest has been obtained with patient in\n supine position. The patient is now intubated, the ETT terminating in the\n trachea some 3 cm above the level of the carina. A right internal jugular\n approach sheath has been placed carrying a Swan-Ganz catheter, tip of which\n reaches the central portion of the pulmonary artery. An NG tube reaches well\n into the stomach. Mediastinal drainage tubes from below are seen. There is a\n left-sided pneumothorax measuring up to 3 cm in width in the apical area but\n extending along the chest lateral wall as well. When comparison is made with\n the next preceding PA and lateral chest examination of ___,\n considerable degree of mediastinal shift towards the right is identified. \n Also noted is that the sternotomy wires have a somewhat different appearance\n indicating that the patient has since then undergone new cardiac operation and\n new sternotomy wire placement. The presently described findings show an acute\n pneumothorax with tension component. A telephone call was placed to extension\n ___. Contact with the responsible cardiac surgeon was established. The\n described findings were communicated verbally and the surgeon assured that the\n situation would be attended immediately. Telephone call was given at 1:50\n p.m. of ___",
"image_path": [
"p16/p16875792/s50476602/b00146a8-daf7d7b9-b5b42300-46be81dc-b7c723c0.jpg"
],
"split": "test"
},
{
"id": "ef9e6f59-22103c28-5c2c7bc8-a2d07454-4c824d0e",
"study_id": 50519818,
"subject_id": 13291370,
"report": "impression: 1. Ill-defined opacity appreciated only on the lateral view in the posterior\n inferior lower lung overlying the spine shadow is concerning for pneumonia and\n since it is not clearly defined on the frontal view, it suggests lower lobe\n pneumonia either involving the right or left side.\n \n 2. COPD.\n \n 3. Pulmonary artery hypertension, unchanged since ___.\n \n Findings were discussed with Dr. ___ on ___ at 5:55\n p.m. Findings: Both lungs are well expanded with mild flattening of the bilateral\n hemidiaphragm and increased AP diameter of the chest consistent with chronic\n pulmonary disease. Bilateral prominent pulmonary arteries raise the concern\n for pulmonary artery hypertension. An ill-defined opacity is seen in\n posterior lower lung in the retrocardiac region overlying the lower spine and\n is concerning for pneumonia. This opacity is not very well defined on the\n frontal view except for a faint opacity in the right lower paracardiac region.\n A single pacemaker lead from left pectoral pacemaker device terminates into\n the right ventricle. Top normal heart size, mediastinal and hilar contours\n are unchanged since ___. Mild atherosclerotic calcification of the\n aortic arch is stable.",
"image_path": [
"p13/p13291370/s50519818/ef9e6f59-22103c28-5c2c7bc8-a2d07454-4c824d0e.jpg"
],
"split": "test"
},
{
"id": "bb31f02a-26cfe8cb-d6444793-d24a3c7a-3ba6afb6",
"study_id": 58301804,
"subject_id": 18855147,
"report": "In comparison with the earlier study of this date, there has been\n placement of a nasogastric tube with its tip in the body of the esophagus. \n The side hole is in the region of the gastroesophageal junction and the tube\n should be advanced several centimeters.\n \n Pulmonary vessels are less well defined than on the previous study, consistent\n with some mild increase in pulmonary venous pressure.",
"image_path": [
"p18/p18855147/s58301804/bb31f02a-26cfe8cb-d6444793-d24a3c7a-3ba6afb6.jpg"
],
"split": "test"
},
{
"id": "a10dea57-90f876f4-c66af250-6fb45322-6ef88ddc",
"study_id": 56661236,
"subject_id": 16662264,
"report": "impression: Right middle lobe and lingular pneumonia. Recommend repeat after treatment to\n document resolution. Findings: PA and lateral views of the chest. There are new bibasilar opacities\n compatible with right middle lobe and lingular pneumonia. Elsewhere, the\n lungs are clear and there is no effusion. Cardiomediastinal silhouette is\n within normal limits. No acute osseous abnormality.",
"image_path": [
"p16/p16662264/s56661236/a10dea57-90f876f4-c66af250-6fb45322-6ef88ddc.jpg"
],
"split": "test"
},
{
"id": "ff6e7a7d-9a6dcd6f-295e7a94-b49fbcc3-502bd3ab",
"study_id": 51664027,
"subject_id": 17206933,
"report": "impression: 1. New right upper and left lower lung heterogeneous opacities are concerning\n for pneumonia.\n \n 3. Increased small to moderate left pleural effusion.\n \n Findings were discussed with Dr. ___ by Dr. ___ at 2:46 a.m. via\n telephone on ___. Findings: Heterogeneous opacities in the right upper lung and left lower lung\n are new compared to radiographs from ___ and concerning for\n infection. A small to moderate left pleural effusion is substantially\n increased. There is no definite right pleural effusion. Heart size is top\n normal. Unfolding of the thoracic aorta is unchanged. Aortic calcifications\n are again noted. Segmental left rib fractures are unchanged.",
"image_path": [
"p17/p17206933/s51664027/ff6e7a7d-9a6dcd6f-295e7a94-b49fbcc3-502bd3ab.jpg"
],
"split": "test"
},
{
"id": "241b6402-15f482d1-da524f5e-92653c29-84172d3d",
"study_id": 53311302,
"subject_id": 12433421,
"report": "impression: Bibasilar atelectasis with decrease in left pleural effusion; no\n pneumothorax. Findings: The right central line tip sits in the mid SVC. The\n cardiomediastinal contours are unchanged. The lungs continue to demonstrate\n mild bibasilar atelectasis. The previously described left pleural effusion\n has decreased. There is no pneumothorax.",
"image_path": [
"p12/p12433421/s53311302/241b6402-15f482d1-da524f5e-92653c29-84172d3d.jpg"
],
"split": "test"
},
{
"id": "cb581d96-edd1855f-79bc7a49-e942ded5-fb83c971",
"study_id": 50035498,
"subject_id": 18309149,
"report": "impression: Stable chest findings, no evidence of pneumothorax following\n chest tube removals. Findings: PA and lateral chest views were obtained with patient in upright\n position. Analysis is performed in direct comparison with the next preceding\n similar study of ___. During the examination interval, the two\n right-sided chest tubes have been removed. No pneumothorax has developed. \n Pleural thickenings and blunting of lateral pleural sinus in right hemithorax\n persist rather unchanged. No new abnormalities.",
"image_path": [
"p18/p18309149/s50035498/cb581d96-edd1855f-79bc7a49-e942ded5-fb83c971.jpg"
],
"split": "test"
},
{
"id": "28737f0b-1389eccb-3debcb12-da4fbf04-3401a0a4",
"study_id": 50093776,
"subject_id": 15612622,
"report": "impression: Stable mediastinal contour which is not widened. Findings: Frontal and lateral views of the chest were obtained. Lungs are\n hyperinflated, flattening of the diaphragms, suggesting chronic obstructive\n pulmonary disease. 7-mm calcific focus in the left mid chest is stable. \n Cardiac silhouette top normal to mildly enlarged. The aorta is tortuous. \n Minimal lingular atelectasis is seen. There is also mild biapical pleural\n thickening. No focal consolidation is seen. There is no pleural effusion or\n pneumothorax. The mediastinal contours are stable and do not appear widened. \n There is diffuse osteopenia.",
"image_path": [
"p15/p15612622/s50093776/28737f0b-1389eccb-3debcb12-da4fbf04-3401a0a4.jpg"
],
"split": "test"
},
{
"id": "de3aab87-d8c3b45e-2312deb9-70e80ce0-17b557d2",
"study_id": 52625540,
"subject_id": 11934114,
"report": "In comparison with study of ___, there has been placement of a\n nasogastric tube with tip in the distal stomach. Otherwise, there is little\n overall change with large right and moderate left pleural effusion with\n enlargement of the cardiac silhouette and evidence of pulmonary vascular\n congestion.",
"image_path": [
"p11/p11934114/s52625540/de3aab87-d8c3b45e-2312deb9-70e80ce0-17b557d2.jpg"
],
"split": "test"
},
{
"id": "ee2fe22f-087ea688-eacd294b-68409208-45f2430d",
"study_id": 52225063,
"subject_id": 15032623,
"report": "In comparison with the study of ___, the cardiac silhouette is\n less prominent and the pulmonary vascularity is substantially improved. Mild\n atelectatic changes are seen at the bases.",
"image_path": [
"p15/p15032623/s52225063/ee2fe22f-087ea688-eacd294b-68409208-45f2430d.jpg"
],
"split": "test"
},
{
"id": "9212c3a6-8bed5158-601c88b9-1f239c51-e1049431",
"study_id": 54010994,
"subject_id": 19759491,
"report": "impression: Lead intended for the right atrium is directed unusually\n posteriorly. While this lead is likely in the right atrium, correlation with\n electrophysiology measurements would be helpful.\n \n These findings were discussed with Dr. ___ by Dr. ___ at 10:50 AM on ___ by telephone ___ minutes after discovery. Findings: There is a biventricular pacer/ICD with leads terminating in the\n coronary sinus and right ventricle. The right atrial lead takes an unusual\n course, directed posteriorly. While this appears unchanged from the prior\n study on the frontal view, an aberrant location should be considered. There\n is no evidence of lead fracture or displacement. Aortic valve prosthesis is\n again noted. Sternotomy wires and mediastinal clips are present.\n \n Moderate cardiomegaly is unchanged. There has been further improvement in the\n mild pulmonary edema. Further aeration of the left lung base is consistent\n with resolving atelectasis and pleural effusions. There is no pneumothorax.",
"image_path": [
"p19/p19759491/s54010994/9212c3a6-8bed5158-601c88b9-1f239c51-e1049431.jpg"
],
"split": "test"
},
{
"id": "29f643b7-e5408002-2f731ee3-cb5b8634-0d438145",
"study_id": 51615087,
"subject_id": 12595991,
"report": "impression: Mild pulmonary edema with probable small bilateral pleural\n effusions. More focal opacities at lung bases may reflect atelectasis but\n infection cannot be completely excluded. Findings: Left-sided pacemaker device is noted with leads\n terminating in the right atrium, right ventricle, and coronary sinus. The\n heart size is mildly enlarged. The aortic knob is calcified. There is mild\n pulmonary edema with perihilar haziness and vascular indistinctness, new from\n the prior study. Focal opacities at lung bases may reflect areas of\n atelectasis though infection cannot be excluded. Small bilateral pleural\n effusions may be present. No pneumothorax is identified.",
"image_path": [
"p12/p12595991/s51615087/29f643b7-e5408002-2f731ee3-cb5b8634-0d438145.jpg"
],
"split": "test"
},
{
"id": "9899772e-b051b74d-f68faa87-f45ebf9b-3fcd4d7b",
"study_id": 57149976,
"subject_id": 16313531,
"report": "impression: Left mid and lower lung opacities concerning for pneumonia. \n Probable small left pleural effusion. Findings: One portable AP upright view of the chest. In the left mid and\n lower lung, there is an opacity concerning for pneumonia. The right lung\n appears clear. There is no pleural effusion on the right. There is no\n evidence of pneumothorax in either lung. The left hemidiaphragm is not well\n seen and a small left pleural effusion cannot be ruled out.",
"image_path": [
"p16/p16313531/s57149976/9899772e-b051b74d-f68faa87-f45ebf9b-3fcd4d7b.jpg"
],
"split": "test"
},
{
"id": "583590d0-c9c3ce35-4b385739-1623390c-62fd1b5d",
"study_id": 55134684,
"subject_id": 16313531,
"report": "impression: 1. Large left pleural effusion with adjacent atelectasis and/or\n consolidation.\n \n 2. Possible subpulmonic component of right pleural effusion. Findings: Stable widening of cardiomediastinal contours with persistent\n silhouetting of left heart border due to a large left pleural effusion with\n adjacent atelectasis and/or consolidation in the left mid and lower lung\n region. On the right, there is apparent elevation of the right hemidiaphragm\n with lateral peaking suggesting the presence of a subpulmonic pleural\n effusion. Areas of adjacent atelectasis in the right mid and lower lung have\n slightly improved.",
"image_path": [
"p16/p16313531/s55134684/583590d0-c9c3ce35-4b385739-1623390c-62fd1b5d.jpg"
],
"split": "test"
},
{
"id": "f0af6b21-c203468f-f3fc3442-bd92e0bb-bf562d09",
"study_id": 56367677,
"subject_id": 19182863,
"report": "In comparison with the study of ___, there has been removal of a\n substantial amount of right pleural fluid. There has been re-expansion of the\n ipsilateral lung with no evidence of pneumothorax. Continued enlargement of\n the cardiac silhouette with some engorgement of pulmonary vessels consistent\n with elevated pulmonary venous pressure.",
"image_path": [
"p19/p19182863/s56367677/f0af6b21-c203468f-f3fc3442-bd92e0bb-bf562d09.jpg"
],
"split": "test"
},
{
"id": "6f619231-f8a0ab48-6858a7eb-b0ee9c1c-de3385c9",
"study_id": 55875120,
"subject_id": 12110863,
"report": "impression: 1. Mild interval increase in interstitial prominence without definite\n pulmonary edema.\n 2. Stable right lower lobe scarring and bronchiectasis. Findings: Since the prior exam, there appears to be increased interstitial\n prominence, although no overt pulmonary edema. Stable bronchiectasis and\n scarring is again noted at the right base. There is no dense consolidation. \n There is no pleural effusion or pneumothorax. Severe cardiomegaly is present.\n A pacemaker is in place with wires in unchanged position. The patient is\n status post a CABG. The sternal wires are intact. There are severe\n degenerative changes of the bilateral shoulders.",
"image_path": [
"p12/p12110863/s55875120/6f619231-f8a0ab48-6858a7eb-b0ee9c1c-de3385c9.jpg"
],
"split": "test"
},
{
"id": "9188d253-7432f199-b8668189-c4b015e6-24ed4f79",
"study_id": 59875098,
"subject_id": 17962324,
"report": "impression: Left basilar opacity which could be compatible with infection. Recommend\n repeat imaging after treatment. If no clincal concern for infection, consider\n chest CT for further evaluation. Findings: An opacity at the base of the right lung is not similar in appearance to chest\n radiograph on ___ and may represent overlapping structures. \n However, an opacity in the retrocardiac clear space on the left is new. \n Additionally, there is an opacity at the left posterior costophrenic The\n cardiomediastinal silhouette and hilar contours are normal. There is no\n pneumothorax. Sternotomy wires and surgical clips are again seen and not\n significantly changed in appearance.",
"image_path": [
"p17/p17962324/s59875098/9188d253-7432f199-b8668189-c4b015e6-24ed4f79.jpg"
],
"split": "test"
},
{
"id": "474c4fbb-14f486fd-a3c9e647-da14a57d-dcf9e39a",
"study_id": 51266767,
"subject_id": 17838301,
"report": "impression: 1. Focal right basilar opacity worrisome for pneumonia.\n \n 2. Mildly prominent pulmonary vasculature suggesting pulmonary venous\n hypertension, but not frank pulmonary edema.\n \n 3. Moderate cardiomegaly.\n \n 4. Calcified pleural plaques. Findings: The heart is moderately enlarged. The aortic arch is calcified. The\n mediastinal and hilar contours appear unchanged. The lung volumes are low. \n Calcified pleural plaques are present. There is no definite pleural effusion\n or pneumothorax. Band-like opacity in the left mid lung suggests minor\n atelectasis or scarring. Pulmonary vessels are somewhat engorged centrally\n suggesting pulmonary venous hypertension if not frank pulmonary edema. There\n is a confluent right basilar opacity worrisome for pneumonia.",
"image_path": [
"p17/p17838301/s51266767/474c4fbb-14f486fd-a3c9e647-da14a57d-dcf9e39a.jpg"
],
"split": "test"
},
{
"id": "2a14617b-2d5db3d5-34f04c3f-f0794b78-c9a89f06",
"study_id": 56036730,
"subject_id": 15204620,
"report": "As compared to the previous radiograph, there is no relevant\n change. Extensive mediastinal right-sided adenopathy with potential volume\n loss in the right upper lobe. Extensive consolidation at the right lung base.\n No newly appeared focal parenchymal opacities. No change in size and aspect\n of the cardiac silhouette. No pleural effusions.",
"image_path": [
"p15/p15204620/s56036730/2a14617b-2d5db3d5-34f04c3f-f0794b78-c9a89f06.jpg"
],
"split": "test"
},
{
"id": "47c8159c-71388595-84bf105d-5a7e99e4-077fb801",
"study_id": 52415062,
"subject_id": 19182863,
"report": "impression: Little change Findings: PA and lateral views of the chest show stability of the moderate\n right pleural effusion with complete collapse of right middle lobe and lower\n lobe. Right upper lobe and left lung are still clear. Median wires are\n related to sternotomy in patient with history of aortic valve replacement and\n are unchanged. Heart size is stable.\n There is no pneumothorax.",
"image_path": [
"p19/p19182863/s52415062/47c8159c-71388595-84bf105d-5a7e99e4-077fb801.jpg"
],
"split": "test"
},
{
"id": "5fd6fa4a-2108246f-d9199b99-e14370ae-0eea894d",
"study_id": 52555178,
"subject_id": 10886362,
"report": "impression: Cardiomegaly and venous congestion. Findings: Right atrial and biventricular pacemaker courses in expected\n position. No significant pleural effusions or pneumothorax. \n Moderate-to-severe cardiomegaly is unchanged. Mild central venous congestion\n and cephalization, but no frank edema. Tiny bilateral pleural effusions. \n There is no focal consolidation. Old healed rib fractures are present on the\n left.",
"image_path": [
"p10/p10886362/s52555178/5fd6fa4a-2108246f-d9199b99-e14370ae-0eea894d.jpg"
],
"split": "test"
},
{
"id": "ee541657-53de178c-acd00b25-6ed17783-b7a8c3da",
"study_id": 58819781,
"subject_id": 13067703,
"report": "impression: Stable chest findings. Persistent loculated pleural density on\n the left base and parenchymal density occupying posterior portions of the left\n lower lobe. Findings: PA and lateral chest views were obtained with the patient in\n upright position. Analysis is performed in direct comparison with the next\n preceding PA and lateral chest examination of ___. Previously\n described heart size, mediastinal structures, and permanent pacer with dual\n electrode system remain unchanged. The same holds also with the previously\n described loculated pleural effusion that blunts the left-sided lateral\n pleural sinus. Parenchymal densities in the posterior portion of the left\n lower lobe remain unchanged as they present on the lateral view. The only\n significant difference is the appearance of substantial amount of\n subdiaphragmatic air which was not found on the preceding chest examination. \n Telephone contact with referring physician, ___. ___, explained this\n finding as the patient is daily abdominal dialysis.",
"image_path": [
"p13/p13067703/s58819781/ee541657-53de178c-acd00b25-6ed17783-b7a8c3da.jpg"
],
"split": "test"
},
{
"id": "8a31b2b4-ae7e2d63-755cd377-936102cb-9bb02fac",
"study_id": 58786693,
"subject_id": 18309149,
"report": "impression: Markedly low lung volumes. Thank basal opacity suggests atelectasis and mild\n edema. Infection or aspiration should be considered in the appropriate\n setting. Findings: Lung volumes are low which accentuates bronchovascular markings and the\n transverse diameter of the heart. Given that, the heart is top-normal to\n minimally enlarged. The pulmonary vasculature is mildly engorged and there is\n mild edema. A right basal opacity suggests atelectasis however infection\n should be considered. No pleural effusion is identified. The left lung is\n clear.",
"image_path": [
"p18/p18309149/s58786693/8a31b2b4-ae7e2d63-755cd377-936102cb-9bb02fac.jpg"
],
"split": "test"
},
{
"id": "42fd3d74-fe3267e7-82ffa036-96225174-327660f6",
"study_id": 53203970,
"subject_id": 15259244,
"report": "impression: Findings suggesting mild pulmonary congestion. Resolution of\n small left-side pleural effusion. Findings: The patient is status post coronary artery bypass graft surgery and\n apparently mitral valve replacement. The heart is mildly enlarged. The\n mediastinal and hilar contours appear unchanged. There is a slight\n interstitial abnormality, suggestive of a state of very mild congestion, but\n no new focal opacity. A left-sided pleural effusion has resolved although\n mild scarring or atelectasis persists. Bones are probably demineralized.",
"image_path": [
"p15/p15259244/s53203970/42fd3d74-fe3267e7-82ffa036-96225174-327660f6.jpg"
],
"split": "test"
},
{
"id": "30fc1707-e38a1f76-d52f9649-78068351-e33cb1b3",
"study_id": 54904275,
"subject_id": 13263843,
"report": "impression: Interval mild improvement in right pleural effusion with likely a\n large residual subpulmonic pleural effusion. Dense opacifications in the now\n apparent right residual lung likely represents a combination of atelectasis\n and known malignancy. Small left pleural effusion. Findings: There is notable interval improvement in the right pleural\n effusion. There is a dense opacification with a rounded contour below the\n aerated right residual lung. Though the contour has the appearance of an\n elevated right hemidiaphragm, this appears to represent a large subpulmonic\n effusion when compared to ___ chest CT. There is improved aeration\n of the right lung with residual opacifications likely representing combination\n of atelectasis and known malignancy; cannot exclude superimposed infectious\n process. Atelectatic changes are noted within the left lower lung with a\n slightly greater degree of collapse in the posterior medial subsegment. Small\n left pleural effusion identified. Abnormal contour of the right upper\n mediastinum is consistent with known malignancy. Left-sided cardiomediastinal\n borders are unremarkable.",
"image_path": [
"p13/p13263843/s54904275/30fc1707-e38a1f76-d52f9649-78068351-e33cb1b3.jpg"
],
"split": "test"
},
{
"id": "70ee568a-e2a70b5f-9f73d45e-c3015d3a-2a6bf3c0",
"study_id": 50078440,
"subject_id": 11022245,
"report": "impression: 1. Bilateral airspace opacity consistent with lobar pneumonia.\n \n 2. Nodular opacity in the left lung apex, recommend attention on followup.\n \n 3. Moderate cardiomegaly. Findings: Portable frontal chest radiographs demonstrate intubated patient,\n the tip of the endotracheal tube is positioned 4.1 cm from the level of the\n carina. An orogastric tube is in place and is coiled within the fundus of the\n stomach. There is airspace opacification of the right lung with relative\n sparing of the apex, as well as basilar left lung opacity. Linear atelectasis\n is seen in the right mid lung. The left lung is relatively clear. A focal\n nodular opacity is seen in the left upper lung measuring 8 mm. There is\n linear atelectasis in the left lower lung. There is no definite effusion. \n There is no pneumothorax. \n \n The heart size is enlarged, the mediastinal contours appear grossly\n unremarkable on this portable film.",
"image_path": [
"p11/p11022245/s50078440/70ee568a-e2a70b5f-9f73d45e-c3015d3a-2a6bf3c0.jpg"
],
"split": "test"
},
{
"id": "be1ddefb-9327567f-aef38bd8-e918043d-91c40219",
"study_id": 53459280,
"subject_id": 19800337,
"report": "impression: Vague nodular opacity projecting over the right lower lung is\n most likely secondary to atelectasis. Consider repeat radiograph with more\n optimal inspiratory effort to further assess. Findings: PA and lateral views of the chest were provided. Vague nodular\n opacity projecting over the right lower lung represents atelectasis, less\n likely pneumonia. No large effusion or pneumothorax is seen. The\n cardiomediastinal silhouette is stable. Imaged osseous structures appear\n intact. No free air is seen below the right hemidiaphragm.",
"image_path": [
"p19/p19800337/s53459280/be1ddefb-9327567f-aef38bd8-e918043d-91c40219.jpg"
],
"split": "test"
},
{
"id": "ac311552-a76f7711-c263444b-9819dc86-6fd39b27",
"study_id": 52692431,
"subject_id": 14295224,
"report": "impression: New right lower lobe aspiration pneumonia. Findings: The patient has had prior esophagectomy with a gastric pull-through. A new\n right lower lobe airspace opacity is likely due to aspiration pneumonia. The\n left lung is clear. There is no pneumothorax. Cardiomediastinal silhouette is\n stable.",
"image_path": [
"p14/p14295224/s52692431/ac311552-a76f7711-c263444b-9819dc86-6fd39b27.jpg"
],
"split": "test"
},
{
"id": "28c782b9-7eb7d267-5a9a998f-25d24646-e811e771",
"study_id": 56506647,
"subject_id": 13263843,
"report": "In comparison with the earlier study of this date, there is little\n overall change in the degree of aeration of the lungs. Some suggested\n increased opacification at the left costophrenic angle could reflect some\n increasing effusion. No evidence of pneumothorax. Evidence of prior right\n upper lobe lobectomy and radiation therapy, better demonstrated on recent CT\n scan.",
"image_path": [
"p13/p13263843/s56506647/28c782b9-7eb7d267-5a9a998f-25d24646-e811e771.jpg"
],
"split": "test"
},
{
"id": "000ffbff-3d93bcef-da8b17cd-fbcede53-51728df9",
"study_id": 50290463,
"subject_id": 10933609,
"report": "impression: 1. Improving right upper lobe consolidation.\n 2. Mild heart failure.\n 3. Findings of chronic lung disease, most likely sarcoidosis. Findings: AP and lateral views of the chest were provided. Lung volumes are\n low, similar to the prior study. The previously noted dense consolidation of\n the right upper lobe has improved with diffuse streaky opacities remaining. \n There are findings consistent with chronic lung disease such as sarcoidosis. \n Prominence of the pulmonary interstitial markings is due to mild heart\n failure. There is no pleural effusion or pneumothorax. The cardiomediastinal\n silhouette is notable for a tortuous aorta. Bones are slightly osteopenic.",
"image_path": [
"p10/p10933609/s50290463/000ffbff-3d93bcef-da8b17cd-fbcede53-51728df9.jpg"
],
"split": "test"
},
{
"id": "3a8c9fa9-90b94fc1-484469e2-d0316be1-245e5d13",
"study_id": 57798090,
"subject_id": 16957952,
"report": "impression: 1. Mild left basal atelectasis; no pneumonia.\n \n 2. Chronic mild to moderate cardiomegaly and pulmonary venous hypertension,\n but no pulmonary edema.\n \n 3. Chronically enlarged atherosclerotic thoracic aorta, with no focal\n aneurysm. Findings: Heterogeneous left basilar opacities do not have a correlate on the\n lateral radiograph and are likely minimal atelectasis. The lungs are\n otherwise clear. Mild pulmonary vascular congestion is not accompanied\n interstitial edema or pleural abnormality. Mild to moderate cardiomegaly is\n chronic. The thoracic aorta is generally enlarged, very tortuous and\n moderately calcified but neither focally aneurysmal nor changed since at least\n ___. The patient has had midline sternotomy and CABG. A right cervical\n rib is seen. Multilevel degenerative changes of the thoracic spine include\n unchanged wedging of a lower thoracic vertebral body.",
"image_path": [
"p16/p16957952/s57798090/3a8c9fa9-90b94fc1-484469e2-d0316be1-245e5d13.jpg"
],
"split": "test"
},
{
"id": "c8502a35-a270d52b-bd1e0d87-6a535418-3c742175",
"study_id": 57273961,
"subject_id": 12952223,
"report": "There is a right IJ central venous line with distal lead tip at the\n cavoatrial junction, stable. There are extensive large pleural effusions,\n right side worse than left. Atelectasis at the left lung base and poor\n inspiratory effort is again visualized. No pneumothoraces are seen. There is\n mild underlying pulmonary edema.",
"image_path": [
"p12/p12952223/s57273961/c8502a35-a270d52b-bd1e0d87-6a535418-3c742175.jpg"
],
"split": "test"
},
{
"id": "64445cbc-ad80926d-3cf56f35-73f41b87-cdaaf288",
"study_id": 59063233,
"subject_id": 15612622,
"report": "impression: Hyperinflated lungs without evidence of pneumonia or CHF. Slight\n mediastinal prominence likely reflects patient's slight leftward rotation. Findings: PA and lateral views of the chest were obtained. The mediastinal\n contour is somewhat prominent, which likely in part reflect patient's slight\n leftward rotation as no mediastinal mass was seen on prior CT. The lungs are\n hyperinflated compatible with COPD. A calcified granuloma is again noted in\n the left mid lung. Calcified lymph nodes in the left hilum are better\n assessed on the prior CT. Heart size is top normal. No definite evidence of\n pneumonia or CHF. No pleural effusion or pneumothorax. The imaged osseous\n structures appear intact.",
"image_path": [
"p15/p15612622/s59063233/64445cbc-ad80926d-3cf56f35-73f41b87-cdaaf288.jpg"
],
"split": "test"
},
{
"id": "af8f292e-eecbb702-9aeef1d2-46861e97-709d3307",
"study_id": 59284918,
"subject_id": 18659631,
"report": "impression: 1. Persistent right upper lobe opacification has only mildly improved since\n ___.\n 2. Multiple rib fractures of varying age and an old left clavicular fracture\n with lytic destruction of the several right lower thoracic ribs more apparent\n since ___. Findings: There is persistent opacification projecting in the lateral aspect of the\n right upper lobe demonstrated along the fissure on the lateral view that is\n mildly improved since ___. There is associated overlying pleural\n abnormality relating to healing rib fractures. There are no new areas of\n focal opacification. There are no pleural effusions or pneumothorax. The\n cardiomediastinal and hilar contours are stable demonstrating moderate\n cardiomegaly and tortuosity of thoracic aorta. A large hiatal hernia is\n unchanged. Pulmonary vascularity is not increased.\n \n There are extensive rib fractures of varying ages. In addition there is lytic\n destruction of several right-sided lower thoracic ribs. There is an old left\n clavicular fracture. There are multiple wedge compression deformities of the\n thoracolumbar spine grossly stable since ___.",
"image_path": [
"p18/p18659631/s59284918/af8f292e-eecbb702-9aeef1d2-46861e97-709d3307.jpg"
],
"split": "test"
},
{
"id": "0e94f694-f43b9926-aae6e13a-c3d97e2d-3a975b5b",
"study_id": 51196890,
"subject_id": 14236258,
"report": "impression: Mild cephalization which could reflect mild pulmonary venous\n congestion. Findings: There is mild cephalization of the\n pulmonary vasculature which is suggestive of increased pulmonary venous\n pressures. The lungs are clear. Rightward deviation of the trachea in the\n superior mediastinum is unchanged and due to the patient's known history of\n thyromegaly. There is no pleural effusion or pneumothorax. The heart is not\n enlarged. A hemodialysis catheter terminates at the cavoatrial junction. \n Again noted are multiple old left rib fractures as well as degenerative\n changes of the bilateral glenohumeral joints.",
"image_path": [
"p14/p14236258/s51196890/0e94f694-f43b9926-aae6e13a-c3d97e2d-3a975b5b.jpg"
],
"split": "test"
},
{
"id": "e6772ec5-79cc92d4-14c206cd-124edc47-86e22fb9",
"study_id": 55536902,
"subject_id": 19565388,
"report": "In comparison with the study of ___, there is little interval\n change. No evidence of acute focal pneumonia or vascular congestion. \n Evidence of previous healed rib fracture on the left and severe loss of height\n of the mid dorsal vertebrae with kyphosis.\n \n This information was telephoned to Dr. ___ at his request.",
"image_path": [
"p19/p19565388/s55536902/e6772ec5-79cc92d4-14c206cd-124edc47-86e22fb9.jpg"
],
"split": "test"
},
{
"id": "47824497-77e713da-b1f179d8-ecf443d2-4fca0009",
"study_id": 56996131,
"subject_id": 15131736,
"report": "In comparison with the study of ___, the monitoring and support\n devices are unchanged. Substantial enlargement of the cardiac silhouette\n persists with extremely prominent pulmonary arteries consistent with pulmonary\n artery hypertension. Some retrocardiac opacification is consistent with\n atelectasis or supervening pneumonia. There are small bilateral effusions\n with some atelectatic change at the right base.",
"image_path": [
"p15/p15131736/s56996131/47824497-77e713da-b1f179d8-ecf443d2-4fca0009.jpg"
],
"split": "test"
},
{
"id": "cfb89eed-31e856eb-8dd16dc1-b7337ecf-1bec8801",
"study_id": 53975458,
"subject_id": 15114531,
"report": "impression: No acute intrathoracic process. Findings: Chest PA and lateral radiograph demonstrates unremarkable\n mediastinal, hilar, and cardiac contours. Lungs are clear. No pleural\n effusion or pneumothorax evident. There has been interval placement of a\n Bravo pH capsule projecting in the expected location of the distal esophagus. \n Surgical clips are seen in the upper abdomen.",
"image_path": [
"p15/p15114531/s53975458/cfb89eed-31e856eb-8dd16dc1-b7337ecf-1bec8801.jpg"
],
"split": "test"
},
{
"id": "3e25d193-509147d7-b305908a-51e0da17-7cb23fda",
"study_id": 53512860,
"subject_id": 10933609,
"report": "impression: Some clearing of aspiration pneumonia. Findings: There has been slight clearing of the aspiration pneumonia since the prior\n chest x-ray of ___. No new foci are present.",
"image_path": [
"p10/p10933609/s53512860/3e25d193-509147d7-b305908a-51e0da17-7cb23fda.jpg"
],
"split": "test"
},
{
"id": "59a9547b-1d1ae94d-21f9b870-53488792-48240baa",
"study_id": 53919021,
"subject_id": 19748558,
"report": "impression: No acute cardiopulmonary process Findings: There is no focal consolidation, effusion, or vascular congestion. The\n cardiomediastinal silhouette is within normal limits. No acute osseous\n abnormalities identified.",
"image_path": [
"p19/p19748558/s53919021/59a9547b-1d1ae94d-21f9b870-53488792-48240baa.jpg"
],
"split": "test"
},
{
"id": "11fac305-a3d8a8fe-cd1ad4a0-fc2a287f-0e061474",
"study_id": 53447402,
"subject_id": 16848073,
"report": "In comparison with study of ___, there is little change in the\n appearance of the heart and lungs. Specifically, following esophagoscopy\n there is no evidence of mediastinal gas or acute pneumonia.",
"image_path": [
"p16/p16848073/s53447402/11fac305-a3d8a8fe-cd1ad4a0-fc2a287f-0e061474.jpg"
],
"split": "test"
},
{
"id": "959ee516-d090d9d5-a95977ac-303cdde2-c9309e8c",
"study_id": 59217830,
"subject_id": 13881772,
"report": "impression: 1. No acute intrathoracic abnormalities identified. Hyperinflated lungs.\n \n 2. 9 mm lung nodule projecting over the anterior second right rib interspace,\n was not well seen on the prior exam. A CT may be helpful for further\n evaluation.\n \n 3. Extensive aortic annular calcifications raise concern for aortic stenosis. Findings: The heart size is top normal. The hilar and mediastinal contours are normal.\n The lungs are hyperinflated, otherwise no focal consolidations concerning for\n pneumonia are identified. Mild left basilar linear atelectasis/ scarring is\n again seen. There is no pneumothorax or pleural effusion. Incidental note is\n made of a 9 mm lung nodule projecting over the right anterior second rib\n interspace. Aortic annular calcifications are again noted. Old healed left\n lower lobe rib fractures are stable.",
"image_path": [
"p13/p13881772/s59217830/959ee516-d090d9d5-a95977ac-303cdde2-c9309e8c.jpg"
],
"split": "test"
},
{
"id": "3b31865b-b41244e4-c46dbdca-c33ad6e4-3cca5768",
"study_id": 56896759,
"subject_id": 11474065,
"report": "impression: Increase in opacity at the right mid to lower lung is nonspecific, could be\n due to infection and/ or aspiration. Findings: Compared the prior study, there is increase in opacity at the right mid to\n lower lung difficult to exclude small left pleural effusion. Pneumonia\n pneumothorax is seen. The cardiac and mediastinal silhouettes are stable. \n Chronic deformity of the posterior right fourth rib.",
"image_path": [
"p11/p11474065/s56896759/3b31865b-b41244e4-c46dbdca-c33ad6e4-3cca5768.jpg"
],
"split": "test"
},
{
"id": "37583135-5e94d264-ff4574d6-cdb16475-77c6bbe2",
"study_id": 54124205,
"subject_id": 17340686,
"report": "impression: 1. Mildly enlarged heart and pulmonary vascular engorgement, unchanged.\n 2. Rounded right basilar opacity may represent asymmetric edema, but other\n processes such as abscess cannot be excluded. At a minimum follow up with\n conventional PA/Lateral radiographs is recommended, ideally CT should be\n considered. Findings: A portable AP upright view of the chest was obtained. Again seen\n is a right-sided dialysis catheter terminating in the right atrium. Heart is\n mildly enlarged. Pulmonary vasculature is mildly engorged. A rounded opacity\n at the right base, present sicne ___, may represent asymmetric pulmonary\n edema, but other processes such as pulmonary abscess cannot be excluded. No\n large effusion, or pneumothorax.",
"image_path": [
"p17/p17340686/s54124205/37583135-5e94d264-ff4574d6-cdb16475-77c6bbe2.jpg"
],
"split": "test"
},
{
"id": "cd202e14-5a239c8c-8bba8f71-28fcffad-3ee8715f",
"study_id": 55562335,
"subject_id": 15659181,
"report": "impression: No acute cardiopulmonary process. Findings: The cardiac silhouette is normal in size. The hilar and mediastinal contours\n are within normal limits. There is mild atelectasis at the right lung base. \n No definite focal consolidation concerning for pneumonia is identified. There\n is no pleural effusion or pneumothorax.",
"image_path": [
"p15/p15659181/s55562335/cd202e14-5a239c8c-8bba8f71-28fcffad-3ee8715f.jpg"
],
"split": "test"
},
{
"id": "495990a5-0e6c123d-d8810c65-d78d662c-7435a7d4",
"study_id": 57427881,
"subject_id": 19907884,
"report": "impression: Low lung volumes and persistent elevation of the right hemidiaphragm. No\n significant interval change. Findings: There are low lung volumes and persistent elevation of the right\n hemidiaphragm. The lungs are clear without focal consolidation. No pleural\n effusion or pneumothorax is seen. The cardiac and mediastinal silhouettes are\n stable.",
"image_path": [
"p19/p19907884/s57427881/495990a5-0e6c123d-d8810c65-d78d662c-7435a7d4.jpg"
],
"split": "test"
},
{
"id": "68bd5521-ca187f93-ae93cbe6-8bb8f491-3fb2dd0f",
"study_id": 50641273,
"subject_id": 13475033,
"report": "impression: Slight increase in interstitial markings in the left mid lung zone which may\n in part relate to peribronchial thickening although atypical infection not\n excluded. The remainder of the study is unchanged. Findings: The cardiac and mediastinal silhouettes are stable. No lobar consolidation is\n seen. There is subtle increased interstitial markings in the left mid lung\n zone, with possible mild peribronchial thickening. No pleural effusion or\n pneumothorax is seen. There is persistent compression of a mid thoracic\n vertebral body.",
"image_path": [
"p13/p13475033/s50641273/68bd5521-ca187f93-ae93cbe6-8bb8f491-3fb2dd0f.jpg"
],
"split": "test"
},
{
"id": "c405b126-03d888ca-314564ad-3797a458-30e53586",
"study_id": 51858688,
"subject_id": 18079481,
"report": "impression: 1. ET tube terminating 1 cm above the carina. The endotracheal tube cuff is\n hyperinflated.\n 2. Unchanged appearance of low lung volumes with superimposed mild\n interstitial edema and central vascular congestion.\n 3. Orogastric tube terminating within the stomach.\n \n The initial findings were discussed by Dr. ___ with the ICU nurse, ___\n ___ via telephone at the time of interpretation, 2:25 p.m. on ___, Findings: The lungs remain underinflated, resulting in bronchovascular crowding. Again\n seen is mild pulmonary vascular congestion and interstitial edema. Multiple\n rib fractures are again seen. An endotracheal tube terminates 1 cm above the\n carina, and the ET tube cuff is hyperinflated. An orogastric tube terminates\n within the stomach. There is no pneumothorax. Small pleural effusions are\n present.",
"image_path": [
"p18/p18079481/s51858688/c405b126-03d888ca-314564ad-3797a458-30e53586.jpg"
],
"split": "test"
},
{
"id": "66b7c679-c157c1f3-e9474f67-86d8cfd8-d63dd1f2",
"study_id": 51102831,
"subject_id": 19800337,
"report": "As compared to the previous radiograph, there is no relevant\n change. The lung volumes have increased, likely reflecting improved\n ventilation. No focal parenchymal opacities suggesting pneumonia. Normal\n size of the cardiac silhouette. Normal appearance of the hilar and\n mediastinal structures. No lung nodules or masses.\n \n Dating back to previous exams from ___, the left hilus has always\n been slightly rounder and denser than on the right. However, no pathologic\n contours are seen and the appearance of the hilus is unchanged with respect to\n size.",
"image_path": [
"p19/p19800337/s51102831/66b7c679-c157c1f3-e9474f67-86d8cfd8-d63dd1f2.jpg"
],
"split": "test"
},
{
"id": "67a32863-338f2899-5e526d84-2639d564-a2204b9b",
"study_id": 56241369,
"subject_id": 16360107,
"report": "impression: Stable chronic abnormalities including bilateral moderate loculated pleural\n effusions and areas of round atelectasis. Findings: The cardiac, mediastinal and hilar contours appear stable. Deshiscences among\n sternal wires appear unchanged. Moderate bilateral pleural effusions appear\n stable a and seem to be due to chronic collections which were also\n characterized on prior CT with associated round atelectasis especially at the\n right lung base. There has been little if any change. Although there is no\n evidence of acute process should be noted that background abnormalities may\n lower the sensitivity of chest radiography.",
"image_path": [
"p16/p16360107/s56241369/67a32863-338f2899-5e526d84-2639d564-a2204b9b.jpg"
],
"split": "test"
},
{
"id": "46f5be5f-70e3e741-542f6fde-edbbdbfe-a4ed00d6",
"study_id": 51640383,
"subject_id": 16043240,
"report": "impression: 1. No acute cardiopulmonary disease. Findings: Note is made again of midline sternotomy wires and mediastinal\n clips, which are stable. Cardiac silhouette is normal. The mediastinal and\n hilar silhouettes are normal. Lungs are clear with no pleural effusion,\n pulmonary edema, or pneumothorax.",
"image_path": [
"p16/p16043240/s51640383/46f5be5f-70e3e741-542f6fde-edbbdbfe-a4ed00d6.jpg"
],
"split": "test"
},
{
"id": "2e87f158-0b24dcfb-c1faa72a-75f96efd-3e82f4c4",
"study_id": 59680684,
"subject_id": 16319601,
"report": "impression: No reaccumulation of pleural fluid or development of\n pneumothorax. Findings: Portable chest radiograph demonstrates unremarkable mediastinal,\n hilar and cardiac contours. There is improved aeration of the lung bases\n particularly on the right. No reaccumulation of pleural effusions or\n development of pneumothorax. Dobbhoff tube is seen with tip in the mid\n stomach. left-sided PICC line tip terminates in the distal SVC.",
"image_path": [
"p16/p16319601/s59680684/2e87f158-0b24dcfb-c1faa72a-75f96efd-3e82f4c4.jpg"
],
"split": "test"
},
{
"id": "1f903004-c567af33-c9cd797b-5d2e4942-f23b2ed3",
"study_id": 53558787,
"subject_id": 12530259,
"report": "impression: Patient with recent left lower lobe lobectomy. Aeration and edema of\n remaining left upper lung has improved. Findings: ET tube ends 4.5 cm above carina. NG tube is in the stomach, and left jugular\n line ends in upper SVC. There is no pneumothorax, and left chest tube is in\n unchanged position in upper hemithorax. Left upper lobe that was collapsed\n yesterday is more aerated and left lung pulmonary edema has significantly\n improved. There is some residual small basilar atelectasis and small pleural\n effusion, if any. Mild subcutaneous air has improved. Right lung is\n unremarkable. Mediastinal and cardiac contours are unchanged.",
"image_path": [
"p12/p12530259/s53558787/1f903004-c567af33-c9cd797b-5d2e4942-f23b2ed3.jpg"
],
"split": "test"
},
{
"id": "dadf469d-f8a75d8f-24e452d6-a7394bb7-ace0708c",
"study_id": 59790228,
"subject_id": 14295224,
"report": "impression: Bibasilar right greater than left opacities, new since prior,\n which could represent infection or potentially aspiration. No other change\n since prior. Findings: Single portable view of the chest. There is increased opacity in\n the right lung, particularly projecting over the base. Right lung base nodule\n is less well seen on the current exam, potentially projectional, and adequate\n comparison for interval change is not possible on this exam. Post-radiation\n changes are again seen in the right paratracheal region. There is also subtle\n opacity at the left lung base in the retrocardiac region. Cardiomediastinal\n silhouette is stable. No acute osseous abnormalities identified. Bridging of\n the posterior right ___ and 7th ribs are again seen.",
"image_path": [
"p14/p14295224/s59790228/dadf469d-f8a75d8f-24e452d6-a7394bb7-ace0708c.jpg"
],
"split": "test"
},
{
"id": "d5aa0315-53869b6c-10151e97-c12a5f0f-d369e178",
"study_id": 57605154,
"subject_id": 16853729,
"report": "impression: Unchanged atelectatic changes. No acute cardiothoracic process. Findings: Again seen are bibasilar and right perihilar atelectatic changes, similar\n compared to ___ and also seen on the CT abdomen and pelvis from ___. There is mild cardiomegaly and mild vascular congestion, but no\n pulmonary edema. Tortuous vessels widen the uppper mediastinum. Chronic right\n rib fractures.",
"image_path": [
"p16/p16853729/s57605154/d5aa0315-53869b6c-10151e97-c12a5f0f-d369e178.jpg"
],
"split": "test"
},
{
"id": "278ebde6-e46251bd-4f894b8e-3ea1ab66-cbea5d97",
"study_id": 57784780,
"subject_id": 14312560,
"report": "In comparison with study of ___, the patient has taken a better\n inspiration. The heart is normal in size and there is no vascular congestion,\n pleural effusion, or acute focal pneumonia.",
"image_path": [
"p14/p14312560/s57784780/278ebde6-e46251bd-4f894b8e-3ea1ab66-cbea5d97.jpg"
],
"split": "test"
},
{
"id": "5732623e-81224052-0d0743d5-220e58d4-18365982",
"study_id": 58255867,
"subject_id": 14236258,
"report": "impression: Vague right mid/lower opacity, nonspecific the could represent infection in\n the proper clinical setting. Findings: Vague opacity projecting over the right mid/lower lung the which is new since\n prior. Elsewhere, the lungs are clear. There is no layering effusion. Cardiac\n silhouette is enlarged but similar in configuration. Multiple vascular stents\n are again noted projecting over the SVC, left brachiocephalic vein and left\n upper extremity. Surgical clips project over the lower neck. No acute osseous\n abnormalities.",
"image_path": [
"p14/p14236258/s58255867/5732623e-81224052-0d0743d5-220e58d4-18365982.jpg"
],
"split": "test"
},
{
"id": "0cda206a-b37c9416-30863ff0-63268f49-76c60c1d",
"study_id": 58955981,
"subject_id": 16435402,
"report": "impression: Lingular opacity likely representing a residual focus of cryptogenic\n organizing pneumonia. Recommend followup chest radiograph in ___ months\n following treatment to document resolution. Findings: There is opacity seen in the region of the lingula, corresponding to the\n consolidation seen on the prior chest CT. Given the patient's symptoms and\n history of a lingular infiltrate, this most likely represents a residual area\n of cryptogenic organizing pneumonia. No additional foci of consolidation are\n noted. There is no pleural effusion, pneumothorax, or pulmonary edema. The\n heart size is normal. Mediastinal and hilar contours are stable.",
"image_path": [
"p16/p16435402/s58955981/0cda206a-b37c9416-30863ff0-63268f49-76c60c1d.jpg"
],
"split": "test"
},
{
"id": "d41d33f4-a726cd71-186c6cd2-c223bd2f-69f4ff76",
"study_id": 57605154,
"subject_id": 16853729,
"report": "impression: Unchanged atelectatic changes. No acute cardiothoracic process. Findings: Again seen are bibasilar and right perihilar atelectatic changes, similar\n compared to ___ and also seen on the CT abdomen and pelvis from ___. There is mild cardiomegaly and mild vascular congestion, but no\n pulmonary edema. Tortuous vessels widen the uppper mediastinum. Chronic right\n rib fractures.",
"image_path": [
"p16/p16853729/s57605154/d41d33f4-a726cd71-186c6cd2-c223bd2f-69f4ff76.jpg"
],
"split": "test"
},
{
"id": "ae38c715-8eeb617e-ad8ab0a9-9f23fdef-9e43fccf",
"study_id": 57844625,
"subject_id": 11204646,
"report": "As compared to the previous radiograph, the patient has been\n intubated. The tip of the endotracheal tube projects 2.8 cm above the carina.\n The patient has also received a nasogastric tube. The course of the tube is\n unremarkable, the tip of the tube is not visible on the current image. The\n right internal jugular vein catheter is in unchanged position.\n \n The atelectatic opacity at the right lung base is slightly increasing. There\n also is a disruption in the air column of the right main bronchus, so that\n bronchoscopic evaluation or clearance of potentially present mucus might be\n indicated.",
"image_path": [
"p11/p11204646/s57844625/ae38c715-8eeb617e-ad8ab0a9-9f23fdef-9e43fccf.jpg"
],
"split": "test"
},
{
"id": "fa62fc78-9b66c0fd-aa7ee648-8b82e0fc-b0e5c0d4",
"study_id": 53971934,
"subject_id": 15612622,
"report": "impression: Atelectasis at right lung base with no acute cardiopulmonary\n process. Findings: The cardiac silhouette demonstrates borderline\n cardiomegaly. Atelectasis is noted at the right lung base. There is no\n evidence of focal consolidation, pleural effusion or pneumothorax. The\n diaphragms appear mildly flattened, and the lungs are hyperinflated,\n suggestive of COPD. Known granuloma is again noted within the left upper\n lobe. The aorta appears tortuous.",
"image_path": [
"p15/p15612622/s53971934/fa62fc78-9b66c0fd-aa7ee648-8b82e0fc-b0e5c0d4.jpg"
],
"split": "test"
},
{
"id": "ad2bd086-921f17c8-b1dd649c-09b63b13-1c0ae6e7",
"study_id": 59616378,
"subject_id": 13352405,
"report": "Comparison is made to the prior study from ___.\n \n There are chest tubes with the distal tips at the right base and right apex. \n The previously seen pigtail catheter at the right base has been removed. \n There is a persistent moderate-sized right pleural effusion. No\n pneumothoraces are seen. There are low lung volumes. Cardiac silhouette is\n within normal limits.",
"image_path": [
"p13/p13352405/s59616378/ad2bd086-921f17c8-b1dd649c-09b63b13-1c0ae6e7.jpg"
],
"split": "test"
},
{
"id": "9961f085-b04f7f91-4556e341-26c1f4f0-28e741d3",
"study_id": 58409548,
"subject_id": 14295224,
"report": "impression: No acute intrathoracic abnormality. Hyperinflated lungs with chronic\n radiation changes. Findings: PA and lateral chest radiograph is compared to prior study dated ___. There has been little interval change with no focal consolidation\n concerning for pneumonia identified. Lungs are hyperinflated. Patient is\n status post radiation therapy to the right lung. Previously seen right lower\n lung sub cm nodular opacity is not definitely visualized. Cardiomediastinal\n contours are stable. There is no pleural effusion or pneumothorax. Visualized\n osseous structures demonstrates no acute abnormality.",
"image_path": [
"p14/p14295224/s58409548/9961f085-b04f7f91-4556e341-26c1f4f0-28e741d3.jpg"
],
"split": "test"
},
{
"id": "98fa0073-4a72a84a-07d17d1b-80f5bc40-e729e67e",
"study_id": 55681597,
"subject_id": 13120957,
"report": "impression: Low lung volumes without radiographic evidence for acute process.\n Bibasilar atelectasis. No evidence of free air beneath the diaphragms. Findings: No focal consolidation, pleural effusion, or pneumothorax is seen. \n Linear retrocardiac densities were seen previously and may represent\n atelectasis. Lung volumes are low, exaggerating pulmonary vasculature and\n hila. Heart and mediastinal contours appear similar compared to prior. There\n is no evidence for free intraperitoneal air below the diaphragms.",
"image_path": [
"p13/p13120957/s55681597/98fa0073-4a72a84a-07d17d1b-80f5bc40-e729e67e.jpg"
],
"split": "test"
},
{
"id": "89318934-c9420a56-2169eec0-c8c097f7-8b4b07d6",
"study_id": 53964812,
"subject_id": 15612622,
"report": "impression: Findings consistent with pneumonia in the right lower lobe. \n Depending on clinical circumstances, the possibility of aspiration could also\n be considered. Findings: T0he cardiac, mediastinal and hilar contours appear stable. There\n is no pleural effusion or pneumothorax. Since the very recent prior studies,\n there is a substantial new opacity in the right lower lobe concerning for\n pneumonia. The bones appear demineralized. There is mild-to-moderate\n rightward convex curvature again centered along the lower thoracic spine with\n incompletely characterized lumbar compression deformities. Moderate\n degenerative changes are again noted along lower thoracic levels.",
"image_path": [
"p15/p15612622/s53964812/89318934-c9420a56-2169eec0-c8c097f7-8b4b07d6.jpg"
],
"split": "test"
},
{
"id": "53a27018-b8c0b2a6-f17c28fb-36c7d96a-9f40c15f",
"study_id": 50952862,
"subject_id": 14744884,
"report": "impression: Mild cardiomegaly with mild interstitial pulmonary edema. Findings: AP upright and lateral views of the chest provided. Vascular stent is seen in\n the region of the right brachiocephalic vein. The heart is moderately\n enlarged. There is mild interstitial pulmonary edema. Previously noted ET and\n NG tubes have been removed. No large pleural effusion. Mediastinal contour is\n stable. Bony structures are sclerotic which could reflect renal\n osteodystrophy.",
"image_path": [
"p14/p14744884/s50952862/53a27018-b8c0b2a6-f17c28fb-36c7d96a-9f40c15f.jpg"
],
"split": "test"
},
{
"id": "cd07db17-9e662fdb-84a7a802-661d6b7a-6538641e",
"study_id": 51143208,
"subject_id": 14147787,
"report": "In comparison with study of ___, there are fibronodular changes\n again seen in the upper zones, consistent with the clinical diagnosis of\n sarcoidosis. No evidence of acute focal pneumonia, vascular congestion, or\n pleural effusion.",
"image_path": [
"p14/p14147787/s51143208/cd07db17-9e662fdb-84a7a802-661d6b7a-6538641e.jpg"
],
"split": "test"
},
{
"id": "677a589e-f87f5a2c-f4ad1883-f7df335b-db658aae",
"study_id": 54629839,
"subject_id": 18978682,
"report": "impression: Low lung volumes with mild patchy opacities in the lung bases. \n This could reflect atelectasis, but infection cannot be completely excluded. Findings: There are low lung volumes. The\n heart size is normal. The aorta remains slightly tortuous with vascular\n calcifications noted. There is crowding of the bronchovascular structures,\n but no overt pulmonary edema is present. Patchy opacities in the lower lobes\n may reflect areas of developing infection or atelectasis. No pleural effusion\n or pneumothorax is present. There are multilevel degenerative changes of the\n thoracic spine. Multiple clips are again noted within the left axilla. \n Degenerative changes of both acromioclavicular joints are noted. Old\n right-sided rib deformities are visualized.",
"image_path": [
"p18/p18978682/s54629839/677a589e-f87f5a2c-f4ad1883-f7df335b-db658aae.jpg"
],
"split": "test"
},
{
"id": "384cf52b-9692fbc2-b3a9f35b-7afe21a3-e935fdb1",
"study_id": 56291217,
"subject_id": 13979643,
"report": "impression: Replaced NG tube tip near the gastroesophageal junction. It\n should be advanced further into the stomach and a repeat film taken before\n use. Findings were discussed with Dr. ___ ___ telephone at ___ on\n ___. Findings: A single portable chest film was obtained. A tip of a newly placed\n NG tube is now seen around the level of the diaphragmatic hiatus. Lung\n volumes are low, accentuating the pulmonary vasculature.",
"image_path": [
"p13/p13979643/s56291217/384cf52b-9692fbc2-b3a9f35b-7afe21a3-e935fdb1.jpg"
],
"split": "test"
},
{
"id": "4ac816f0-20d6f585-6b55a743-653f83da-3490fb22",
"study_id": 52356800,
"subject_id": 19182863,
"report": "impression: Interval increase in right pleural effusion with complete\n atelectasis of the right middle and lower lobes, raising concern for bronchial\n obstruction.\n \n The above findings were communicated to Dr. ___ by Dr. ___ ___\n telephone at 4:55pm, ___ min after discovery. Findings: PA and lateral views of the chest demonstrate interval increase in\n size of right pleural effusion, along with complete atelectasis of the right\n middle and lower lobes, raising concern for bronchial obstruction. The right\n upper lobe and left lung are grossly clear. The heart size is unchanged. \n Median sternotomy wires and post-surgical changes associated with aortic valve\n replacement are unchanged.",
"image_path": [
"p19/p19182863/s52356800/4ac816f0-20d6f585-6b55a743-653f83da-3490fb22.jpg"
],
"split": "test"
},
{
"id": "c462d814-c520caef-649ccd0c-e754aafa-4e59889d",
"study_id": 50227249,
"subject_id": 18767957,
"report": "impression: No acute cardiopulmonary process. Findings: Frontal and lateral views of the chest were obtained. No focal\n consolidation, pleural effusion, or evidence of pneumothorax is seen. \n Mediastinal contours are stable. The hila are less prominent likely due to\n decrease in previous mild fluid overload. The heart is top normal to mildly\n enlarged.",
"image_path": [
"p18/p18767957/s50227249/c462d814-c520caef-649ccd0c-e754aafa-4e59889d.jpg"
],
"split": "test"
},
{
"id": "201ac57d-bf4004d7-41445e4a-91f50e03-e786df90",
"study_id": 58836461,
"subject_id": 15192710,
"report": "impression: Small left pleural effusion and improving atelectasis, but no\n pneumothorax. Findings: The cardiomediastinal and hilar contours are normal. Subtle linear\n horizontally oriented opacities in the left costophrenic angle appear improved\n compared to prior exams and likely reflect the sequelae of resolving\n atelectasis. There is no pneumothorax. A small left pleural effusion is\n seen.",
"image_path": [
"p15/p15192710/s58836461/201ac57d-bf4004d7-41445e4a-91f50e03-e786df90.jpg"
],
"split": "test"
},
{
"id": "bf3ca23d-9ae54a6f-679d2476-6eb17d30-ee3cf5ee",
"study_id": 58737609,
"subject_id": 16553329,
"report": "impression: Interval resolution of the prior pulmonary edema, with stable moderate to\n large bilateral pleural effusions. No evidence of focal consolidation within\n the visualized upper lobes. Findings: The examination is somewhat limited by low lung volumes. Redemonstrated are\n moderate to large bilateral pleural effusions. As compared to the prior\n examination, there has been resolution of the pulmonary edema. No focal\n consolidation or pneumothorax is seen. The heart size is not well assessed,\n but appears to be at least mildly enlarged. Mediastinal contours are stable.",
"image_path": [
"p16/p16553329/s58737609/bf3ca23d-9ae54a6f-679d2476-6eb17d30-ee3cf5ee.jpg"
],
"split": "test"
},
{
"id": "95efb462-e05c1ac9-3c5319d6-bafdcede-df6db042",
"study_id": 58267855,
"subject_id": 10268877,
"report": "Comparison is made to the prior study performed two hours earlier.\n \n Interval placement of a nasogastric tube, whose distal tip and sideport are\n below the gastroesophageal junction. Endotracheal tube and right IJ central\n line are in unchanged position. There is persistent cardiomegaly. There is a\n left retrocardiac opacity. There is prominence of the pulmonary vascular\n markings, consistent with mild pulmonary edema. There is some atelectasis at\n the left lung base.",
"image_path": [
"p10/p10268877/s58267855/95efb462-e05c1ac9-3c5319d6-bafdcede-df6db042.jpg"
],
"split": "test"
},
{
"id": "e18e6623-ee725070-b05a75c1-a11fea0c-9d3f0868",
"study_id": 57432088,
"subject_id": 15378103,
"report": "impression: Improved aeration of the apices since ___. Extensive\n bilateral dense consolidations remain at the bases. Given rapid improvement,\n TRALI or ARDS are more likely etiologies than pneumonia. Findings: A single portable semi-erect chest radiograph was obtained. \n Aeration of the lungs has improved since ___. In particular the\n apices are better aerated. Persistent alveolar opacity remains in a bibasilar\n predominance. Small right effusion, if any, is unchanged. There is no new\n abnormality of the heart or mediastinum. There is no pneumothorax or\n consolidation. An endotracheal tube remains in the upper airway. An enteric\n catheter extends inferiorly out of field of view. Right-sided PICC line tip\n terminates in the low SVC. Pacemaker leads are in unchanged positions. \n Median sternotomy wires are intact.",
"image_path": [
"p15/p15378103/s57432088/e18e6623-ee725070-b05a75c1-a11fea0c-9d3f0868.jpg"
],
"split": "test"
},
{
"id": "df66e950-78bfa09d-ccc14e43-193ef713-3c2bd5a4",
"study_id": 55947318,
"subject_id": 11928692,
"report": "impression: Findings suggesting mild interstitial pulmonary edema along with\n mild cardiomegaly and linear atelectasis at the left lung base. No evidence\n of acute pneumonia or pneumothorax. Findings: Left ventricular pacemaker device is again\n noted with appropriately positioned right atrial and right ventricular leads. \n Mild cardiomegaly is unchanged from ___. Mild pulmonary venous\n congestion with cephalization and predominantly perihilar opacities consistent\n with mild interstitial pulmonary edema appears similar to chest radiograph of\n ___. There is no evidence of pleural effusion or pneumothorax. \n There is linear atelectasis at the left lung base, similar to the prior\n examination. Loss of height of a upper mid thoracic vertebral body is\n unchanged compared to ___.",
"image_path": [
"p11/p11928692/s55947318/df66e950-78bfa09d-ccc14e43-193ef713-3c2bd5a4.jpg"
],
"split": "test"
},
{
"id": "2c64848d-cd007bfa-b3e2c794-d206cd7b-26b4ec95",
"study_id": 59839373,
"subject_id": 14851532,
"report": "impression: 1. Incompletely characterized known pulmonary nodules concerning for\n malignancy.\n \n 2. Unchanged subsegmental basilar atelectasis and possible small bilateral\n pleural effusions.\n \n 3. Increased opacity in the right mid lung may reflect pneumonia or possibly\n asymmetric pulmonary edema. Findings: Known heterogeneous consolidation in the\n left mid lung is not well seen on this single frontal view. Additional known\n nodules are also not well characterized on this radiographic examination. \n Linear opacities in the lung bases are similar compared to prior and likely\n reflect subsegmental atelectasis. No overt pulmonary edema is identified. \n Increased attenuation in the right mid-lung could reflect pneumonia or\n asymmetric pulmonary edema. Mild blunting of the bilateral costophrenic\n angles is unchanged and possibly due to small effusions or chronic pleural\n thickening. Cardiomediastinal and hilar contours are within normal limits.",
"image_path": [
"p14/p14851532/s59839373/2c64848d-cd007bfa-b3e2c794-d206cd7b-26b4ec95.jpg"
],
"split": "test"
},
{
"id": "222087fc-b3297c5c-72502065-cf9f3e90-6839efc7",
"study_id": 51235553,
"subject_id": 12433421,
"report": "As compared to the previous radiograph, the pre-existing left\n pleural effusion has massively increased in extent. The effusion occupies\n approximately half of the left hemithorax and causes substantial basal\n atelectasis.\n \n On the right, a small-to-moderate pleural effusion has newly occurred. In the\n ventilated parts of the lung parenchyma, there is no evidence of pneumonia. \n No pneumothorax.",
"image_path": [
"p12/p12433421/s51235553/222087fc-b3297c5c-72502065-cf9f3e90-6839efc7.jpg"
],
"split": "test"
},
{
"id": "ca72c0af-97077c68-1cf042a0-d9128e34-f775403e",
"study_id": 52399735,
"subject_id": 13263843,
"report": "As compared to the previous radiograph, the lateral images show\n that the right pleural effusion does not layer, which would be consistent with\n loculation. Also, there is an increase in adjacent atelectasis.",
"image_path": [
"p13/p13263843/s52399735/ca72c0af-97077c68-1cf042a0-d9128e34-f775403e.jpg"
],
"split": "test"
},
{
"id": "a4849658-ce9b054b-b59e436d-df3b5ab8-80025982",
"study_id": 55611611,
"subject_id": 11204646,
"report": "impression: Interval decrease in size of small right pleural effusion with mild right\n basilar atelectasis. Findings: The study is somewhat limited due to patient rotation. The heart remains\n moderate to severely enlarged. Mediastinal widening is unchanged compared to\n the prior studies. The pulmonary vascularity is normal. Small right pleural\n effusion has decreased in the interval. Left lung is clear. There is minimal\n atelectasis in the right lung. No pneumothorax is present. No acute osseous\n abnormality is seen.",
"image_path": [
"p11/p11204646/s55611611/a4849658-ce9b054b-b59e436d-df3b5ab8-80025982.jpg"
],
"split": "test"
},
{
"id": "d3ecfa7f-1a24312c-7a107e83-9ee0345c-edfe5bc0",
"study_id": 50093776,
"subject_id": 15612622,
"report": "impression: Stable mediastinal contour which is not widened. Findings: Frontal and lateral views of the chest were obtained. Lungs are\n hyperinflated, flattening of the diaphragms, suggesting chronic obstructive\n pulmonary disease. 7-mm calcific focus in the left mid chest is stable. \n Cardiac silhouette top normal to mildly enlarged. The aorta is tortuous. \n Minimal lingular atelectasis is seen. There is also mild biapical pleural\n thickening. No focal consolidation is seen. There is no pleural effusion or\n pneumothorax. The mediastinal contours are stable and do not appear widened. \n There is diffuse osteopenia.",
"image_path": [
"p15/p15612622/s50093776/d3ecfa7f-1a24312c-7a107e83-9ee0345c-edfe5bc0.jpg"
],
"split": "test"
},
{
"id": "ef34a791-15321a3d-aa9eca93-84157fc9-6fccd907",
"study_id": 58248722,
"subject_id": 16826047,
"report": "impression: Increased right pleural loculated effusion with chest tube in\n place. Increasing consolidation in the right lung is concerning for\n pneumonia. Findings: PA and lateral views of the chest provided. Port-A-Cath is\n unchanged in position with its tip positioned in the expected location of the\n mid SVC. A right pleural drain is in place with increased opacity in the\n right lung and probable increase in size of the loculated right pleural\n effusion. Findings are concerning for a superimposed consolidation/pneumonia.\n The left lung remains essentially clear. The heart is difficult to assess\n given the effacement of the right heart border. The prominence of the\n mediastinum may reflect in part adjacent loculated pleural fluid. No\n pneumothorax is seen.",
"image_path": [
"p16/p16826047/s58248722/ef34a791-15321a3d-aa9eca93-84157fc9-6fccd907.jpg"
],
"split": "test"
},
{
"id": "69392c89-8fa3a6e8-6c3bc53f-f09b09e2-a33a44e3",
"study_id": 54655485,
"subject_id": 13475033,
"report": "impression: No definite acute cardiopulmonary process. Findings: Frontal and lateral views of the chest. The lungs are clear of focal\n consolidation, effusion or pneumothorax. The heart is enlarged, similar to\n prior. Right upper extremity vascular stent is partially visualized. \n Multiple thoracic compression deformities are again seen.",
"image_path": [
"p13/p13475033/s54655485/69392c89-8fa3a6e8-6c3bc53f-f09b09e2-a33a44e3.jpg"
],
"split": "test"
},
{
"id": "5757b72f-454a5bc3-efa625b3-859d88b2-a2bd2112",
"study_id": 59505688,
"subject_id": 12963531,
"report": "impression: 1. Mild interstitial pulmonary edema.\n 2. Massive cardiomegaly, not significantly changed.\n 3. Small bilateral pleural effusions, not significantly changed. Findings: AP and lateral radiographs of the chest were acquired. The heart\n is massively enlarged, as before. Small bilateral pleural effusions are not\n significantly changed. Diffuse interstitial opacities with perihilar\n predominance are likely secondary to mild interstitial pulmonary edema,\n increased compared to radiographs from ___. No focal\n consolidations concerning for pneumonia. There is no pneumothorax. The\n mediastinal contours are stable.",
"image_path": [
"p12/p12963531/s59505688/5757b72f-454a5bc3-efa625b3-859d88b2-a2bd2112.jpg"
],
"split": "test"
},
{
"id": "070b58a0-da9b8080-6eeeaf5a-46226e7b-2f9453fa",
"study_id": 54100996,
"subject_id": 12145137,
"report": "impression: 1. Left suprahilar opacity and fiducial seeds are again seen, although\n appears slightly less prominent/small in size, although as mentioned on the\n prior study, could be further evaluated by chest CT or PET-CT.\n 2. Right hilum appears slightly more prominent as compared to the prior\n study, which may be due to patient positioning, although increased right hilar\n lymphadenopathy is not excluded. Findings: AP portable view of the chest is obtained. Previously seen left\n juxtahilar opacity lateral to the fiducial seeds has decreased in size and\n persists since the prior study. No new focal consolidation is seen.There is\n prominence of the right hilum which is slightly increased since the prior\n study, which may relate to patient positioning, although underlying increased\n lymphadenopathy cannot be excluded. A left subclavian central venous catheter\n is again seen, unchanged in position. Cardiac and mediastinal silhouettes are\n stable. Chronic right chest wall deformity again seen.",
"image_path": [
"p12/p12145137/s54100996/070b58a0-da9b8080-6eeeaf5a-46226e7b-2f9453fa.jpg"
],
"split": "test"
},
{
"id": "f2075bc9-3c92d658-0f36d71a-9df38119-d2fafe13",
"study_id": 53788698,
"subject_id": 19844485,
"report": "impression: Mild pulmonary vascular congestion. Cardiomegaly. Pulmonary\n nodules documented on CT from ___ are better appreciated on that study. Findings: Frontal and lateral views of the chest were obtained. Cardiac and\n mediastinal silhouettes are stable with the cardiac silhouette\n mild-to-moderately enlarged. There is mild pulmonary vascular congestion. No\n pleural effusion or pneumothorax is seen. Degenerative changes are seen along\n the spine.",
"image_path": [
"p19/p19844485/s53788698/f2075bc9-3c92d658-0f36d71a-9df38119-d2fafe13.jpg"
],
"split": "test"
},
{
"id": "e3ee1499-119d0bc0-6cddf725-9d2d60d8-d34f9fc7",
"study_id": 57910301,
"subject_id": 12185775,
"report": "impression: No evidence of pulmonary edema.\n Increased small left pleural effusion.\n Stable moderate cardiomegaly. Findings: The ET and NG tubes have been removed. A right PICC line terminates in the low\n SVC. Calcified left lung nodules are unchanged. The lungs are otherwise\n clear except for left basilar atelectasis. A small left pleural effusion has\n developed. Moderate cardiomegaly is unchanged.",
"image_path": [
"p12/p12185775/s57910301/e3ee1499-119d0bc0-6cddf725-9d2d60d8-d34f9fc7.jpg"
],
"split": "test"
},
{
"id": "8ee276bc-f8413bb2-79639432-b58d2a14-2d9f78c0",
"study_id": 52998742,
"subject_id": 14236258,
"report": "impression: Small right pleural effusion. Otherwise unremarkable. Findings: AP upright and lateral views of the chest were provided. A\n vascular stent is again noted in the region of the SVC, left brachiocephalic\n vein. There is blunting of the right CP angle which could indicate a small\n effusion. No overt signs of edema or pneumonia. The cardiomediastinal\n silhouette is stable. Bony structures are intact. Degenerative changes again\n noted at the left glenohumeral joint.",
"image_path": [
"p14/p14236258/s52998742/8ee276bc-f8413bb2-79639432-b58d2a14-2d9f78c0.jpg"
],
"split": "test"
},
{
"id": "352f1f90-b49aaf35-a359c107-f209944e-a4814903",
"study_id": 53158507,
"subject_id": 16553329,
"report": "impression: Small bilateral pleural effusions. Please note that Chest CTA is recommended\n if there is a concern for pulmonary embolism. Findings: Heart size is mildly enlarged. The mediastinal and hilar contours\n unremarkable. Calcified granulomas are noted within the left upper lung\n field. No focal consolidation or pneumothorax is present. The pulmonary\n vascularity is not engorged. There are small bilateral pleural effusions,\n best seen on the lateral view. No acute osseous abnormalities demonstrated.",
"image_path": [
"p16/p16553329/s53158507/352f1f90-b49aaf35-a359c107-f209944e-a4814903.jpg"
],
"split": "test"
},
{
"id": "00f1a123-51de83f7-4d563a12-f705f4f0-4683b4eb",
"study_id": 52930189,
"subject_id": 17669276,
"report": "Patient is rotated slightly to the right. The patient is status\n post median sternotomy. Enlargement of the cardiomediastinal silhouette is\n grossly stable as compared to the prior study. There are small bilateral\n pleural effusions. Interstitial prominence suggests interstitial edema. Left\n retrocardiac opacity is seen which may be due to combination of pleural\n effusion and atelectasis, although focal consolidation is not excluded.",
"image_path": [
"p17/p17669276/s52930189/00f1a123-51de83f7-4d563a12-f705f4f0-4683b4eb.jpg"
],
"split": "test"
},
{
"id": "4bb967c3-58f8c025-777fd624-8d104e92-18a9526a",
"study_id": 56024784,
"subject_id": 19549821,
"report": "impression: No acute cardiopulmonary process. Findings: The cardiac silhouette is normal in size. The mediastinal and\n hilar contours are within normal limits. The pulmonary vasculature is not\n engorged. The lungs are well expanded and well aerated without focal\n consolidation concerning for pneumonia. No pleural effusion or pneumothorax\n is detected. Mild biapical pleural thickening is symmetrical.",
"image_path": [
"p19/p19549821/s56024784/4bb967c3-58f8c025-777fd624-8d104e92-18a9526a.jpg"
],
"split": "test"
},
{
"id": "940ed972-9b210254-8ce47743-d277b7b7-d440de02",
"study_id": 57663243,
"subject_id": 16855430,
"report": "impression: Pulmonary edema, small bilateral pleural effusions, mild\n cardiomegaly. Findings: Frontal and lateral views of the chest were obtained. Bilateral\n pleural effusions are seen as well as persistent pulmonary edema. Stable mild\n cardiomegaly noted. No interval changes are seen.",
"image_path": [
"p16/p16855430/s57663243/940ed972-9b210254-8ce47743-d277b7b7-d440de02.jpg"
],
"split": "test"
},
{
"id": "d7a25de4-e2d563e2-93017e5e-4127bd89-0d081f33",
"study_id": 52399735,
"subject_id": 13263843,
"report": "As compared to the previous radiograph, the lateral images show\n that the right pleural effusion does not layer, which would be consistent with\n loculation. Also, there is an increase in adjacent atelectasis.",
"image_path": [
"p13/p13263843/s52399735/d7a25de4-e2d563e2-93017e5e-4127bd89-0d081f33.jpg"
],
"split": "test"
},
{
"id": "bbeb5006-95cd0d0e-263c6445-ee37f7f9-a48dd6ab",
"study_id": 54917064,
"subject_id": 14794396,
"report": "impression: New nodular opacity in the right upper lobe, concerning for\n metastatic disease, less likely infection in this patient with known history\n of RCC. A chest CT is recommended for further evaluation. Findings: The cardiomediastinal and hilar contours\n are normal. In comparison to the prior study, a nodular opacity in the right\n upper lobe measuring approximately 13 mm, is new. The left lung appears\n relatively clear. No focal consolidation, pleural effusion, or pneumothorax\n is seen. No acute osseous abnormality is detected. Surgical clips are seen\n in the left paraspinal region in the abdomen, consistent with prior\n nephrectomy.",
"image_path": [
"p14/p14794396/s54917064/bbeb5006-95cd0d0e-263c6445-ee37f7f9-a48dd6ab.jpg"
],
"split": "test"
},
{
"id": "58742345-8a241152-4b4d44c2-4b3196da-324efa44",
"study_id": 56201710,
"subject_id": 18906643,
"report": "Compared with the study of ___, there has been placement of a\n hemodialysis catheter that extends into the right atrium. The other\n monitoring and support devices are essentially unchanged. Continued\n enlargement of the cardiac silhouette with some elevation of pulmonary venous\n pressure. Probable bilateral pleural effusions.",
"image_path": [
"p18/p18906643/s56201710/58742345-8a241152-4b4d44c2-4b3196da-324efa44.jpg"
],
"split": "test"
},
{
"id": "f1324f6e-a72d0eb7-dbe2b51f-8da51dcb-822e61dc",
"study_id": 58373469,
"subject_id": 13896515,
"report": "impression: Slight interval improvement in interstitial pulmonary edema. Findings: As compared to the prior radiograph performed yesterday morning, there has\n been slight interval improvement in extent of interstitial pulmonary edema.\n There are no large pleural effusions. There is no pneumothorax. Persistent\n moderate cardiomegaly. Median sternotomy wires are intact. Left pectoral\n pacemaker is unchanged in visualized.",
"image_path": [
"p13/p13896515/s58373469/f1324f6e-a72d0eb7-dbe2b51f-8da51dcb-822e61dc.jpg"
],
"split": "test"
},
{
"id": "318e2d2a-cd564b66-987b939f-2b0ded80-8fc82ad2",
"study_id": 55593187,
"subject_id": 19549821,
"report": "impression: No acute cardiopulmonary process. Findings: AP and lateral views of the chest. The lungs are clear of consolidation,\n effusion or pulmonary vascular congestion. Cardiomediastinal silhouette is\n stable in configuration. Vascular coronary stent is also noted.Nodular\n opacity projecting over the right mid lung laterally is compatible with\n callous from prior rib fracture. Chronic changes noted at the proximal left\n humerus suggestive of prior trauma. No acute osseous abnormality detected.",
"image_path": [
"p19/p19549821/s55593187/318e2d2a-cd564b66-987b939f-2b0ded80-8fc82ad2.jpg"
],
"split": "test"
},
{
"id": "dc1a93ef-539208d4-97e94a0c-0081a869-6bf2996a",
"study_id": 52033279,
"subject_id": 19731864,
"report": "impression: Moderately enlarged heart size, stable since ___. No\n findings concerning for pulmonary edema or pneumonia. Findings: Enlarged heart size is stable since ___. Mediastinal and hilar\n contours are unremarkable. Aorta is tortuous in course, unchanged in\n appearance. There are no lung opacities concerning for pulmonary\n edema/pneumonia. There is no pleural effusion.",
"image_path": [
"p19/p19731864/s52033279/dc1a93ef-539208d4-97e94a0c-0081a869-6bf2996a.jpg"
],
"split": "test"
},
{
"id": "a5d858a3-f180454b-311e1427-1b70d6f0-3d95426d",
"study_id": 56918682,
"subject_id": 15192710,
"report": "impression: Stable chest findings, no evidence of new acute pulmonary\n infectious process that could account for unexplained leukocytosis. Findings: PA and lateral chest views were obtained with patient in upright\n position. Analysis is performed in direct comparison with the next preceding\n similar study of ___. The chest findings are completely stable,\n and there is no evidence of new pulmonary parenchymal infiltrates that could\n represent a pneumonia. Heart size is also unchanged, and no evidence of\n pulmonary vascular congestion or pleural effusion exists. No pneumothorax in\n the apical area.",
"image_path": [
"p15/p15192710/s56918682/a5d858a3-f180454b-311e1427-1b70d6f0-3d95426d.jpg"
],
"split": "test"
},
{
"id": "f05b9731-d6bf3b29-6197f242-4cc974a3-fe0f5b56",
"study_id": 57935403,
"subject_id": 17112432,
"report": "impression: Small right apical pneumothorax.\n \n Findings were discussed with Dr. ___ by Dr. ___ by telephone on\n ___ at 10:40 a.m., time of discovery 10:35 a.m. Findings: Comparison is made to prior examination of ___. The ET\n tube has been removed. A small right apical pneumothorax is identified. \n There is a small amount of subcutaneous emphysema in the right supraclavicular\n region in the neck, which is not significantly changed. Again noted are hazy\n opacities in the right hemithorax and these are stable.",
"image_path": [
"p17/p17112432/s57935403/f05b9731-d6bf3b29-6197f242-4cc974a3-fe0f5b56.jpg"
],
"split": "test"
},
{
"id": "c3827619-5b104baa-e1895045-007f9978-837ef55e",
"study_id": 56993533,
"subject_id": 15182529,
"report": "impression: 1. No evidence of acute disease. \n \n 2. Newly apparent nodular focus projecting along the right lower lung,\n probably a nipple shadow, although a pulmonary nodule should be considered. \n When clinically appropriate, repeat PA view with nipple markers is\n recommended. Findings: The heart is normal in size. The aortic arch is calcified. The\n mediastinal and hilar contours appear unchanged. There is no pleural effusion\n or pneumothorax. There is a nodular focus projecting over the right lower\n lung, probably a nipple shadow, although not visualized on prior radiographs. \n Otherwise the lung fields appear clear.",
"image_path": [
"p15/p15182529/s56993533/c3827619-5b104baa-e1895045-007f9978-837ef55e.jpg"
],
"split": "test"
},
{
"id": "97766a6d-6ee96b98-90cacba0-3eb50d93-77416ad1",
"study_id": 50281752,
"subject_id": 15185305,
"report": "impression: 1) Slight increase in size of small left pleural effusion. \n 2) No new opacities to suggest aspiration. Findings: A feeding tube is seen within the stomach. Accounting for the\n positional differences due to patient's rotation, there has been no change in\n the cardiomediastinal silhouette. Stable calcification of the aortic knob is\n noted. Since the prior radiograph, there has been a slight increase in size\n of the left pleural effusion. There is no effusion on the right. The left\n pulmonary mass is unchanged. There is no new consolidation. Stable right\n lower rib fractures are unchanged. There is no pneumothorax.",
"image_path": [
"p15/p15185305/s50281752/97766a6d-6ee96b98-90cacba0-3eb50d93-77416ad1.jpg"
],
"split": "test"
},
{
"id": "9c51d1ec-858c08f3-1185729c-961916ad-9628d6b8",
"study_id": 58826933,
"subject_id": 19623993,
"report": "Compared to the previous radiograph, there is no relevant change. \n The left internal jugular vein catheter has been removed, the nasogastric tube\n remains in place. Unchanged borderline size of the cardiac silhouette with\n minimal fluid overload. An area of atelectasis at the left lung bases is\n constant. There is no evidence of interval appearance of pneumonia. No\n pneumothorax.",
"image_path": [
"p19/p19623993/s58826933/9c51d1ec-858c08f3-1185729c-961916ad-9628d6b8.jpg"
],
"split": "test"
},
{
"id": "ee20ed6a-2dc0af0c-24d33cf6-5386e01a-c281e8c5",
"study_id": 51274564,
"subject_id": 16508811,
"report": "impression: Status post placement of new left internal jugular central venous catheter; no\n pneumothorax identified. Findings: A new central venous catheter terminates in the left brachiocephalic vein. \n There is no pneumothorax. Otherwise, there has been no significant short-term\n change.",
"image_path": [
"p16/p16508811/s51274564/ee20ed6a-2dc0af0c-24d33cf6-5386e01a-c281e8c5.jpg"
],
"split": "test"
},
{
"id": "9ed98f0d-44106851-df647480-672d93ed-95426753",
"study_id": 56230969,
"subject_id": 12303667,
"report": "impression: Peristent diffuse interstitial abnormalies. No evidence of pneumonia. Findings: A frontal and lateral view of the chest demonstrate a diffuse interstitial\n abnormality. There are no focal areas of consolidation to suggest pneumonia. \n The cardiomediastinal and hilar contours are normal. There is no pleural\n effusion or pneumothorax.",
"image_path": [
"p12/p12303667/s56230969/9ed98f0d-44106851-df647480-672d93ed-95426753.jpg"
],
"split": "test"
},
{
"id": "943eea27-fbd84e49-bf38a522-5020d59e-0c6c7541",
"study_id": 51780481,
"subject_id": 16848073,
"report": "impression: Slight decrease in bilateral pleural effusions with otherwise\n stable post-changes in comparison to prior study from yesterday. Findings: Post-surgical changes are again noted within the esophagus. \n Bilateral pleural effusions are noted, right greater than left, and appear\n slightly decreased in comparison to prior study from yesterday. \n Cardiomediastinal silhouette remains stable. The lungs are without any focal\n consolidations or pneumothoraces.",
"image_path": [
"p16/p16848073/s51780481/943eea27-fbd84e49-bf38a522-5020d59e-0c6c7541.jpg"
],
"split": "test"
},
{
"id": "ccb23713-fc3403f9-ed87ad5d-f67a8be5-b4067886",
"study_id": 57120452,
"subject_id": 14744884,
"report": "impression: Stable mild pulmonary vascular congestion and mild cardiomegaly. Findings: Lung volumes are slightly low, as before, with persistent mild pulmonary\n vascular congestion and mild cardiomegaly. No focal consolidation concerning\n for pneumonia is identified. There is no pneumothorax. A metallic right\n subclavian vein stent is unchanged.",
"image_path": [
"p14/p14744884/s57120452/ccb23713-fc3403f9-ed87ad5d-f67a8be5-b4067886.jpg"
],
"split": "test"
},
{
"id": "2883541d-6a242b68-0838ecc7-5cd20cbf-133ec77b",
"study_id": 56925922,
"subject_id": 10439781,
"report": "impression: No evidence of acute disease. Severe pulmonary fibrosis, not\n significantly changed. Findings: A Port-A-Cath terminates in the upper right atrium. The cardiac,\n mediastinal and hilar contours appear unchanged. Fine reticulation associated\n with pulmonary fibrosis appears very similar within each lung in extent and\n distribution with no significant superimposed change. The lung volumes are\n low. There is no pleural effusion or pneumothorax. Multiple compression\n deformities including lower thoracic vertebroplasties appear unchanged.",
"image_path": [
"p10/p10439781/s56925922/2883541d-6a242b68-0838ecc7-5cd20cbf-133ec77b.jpg"
],
"split": "test"
},
{
"id": "6eaf56a0-ded30052-29edb3ad-20da2133-db0cf728",
"study_id": 53919021,
"subject_id": 19748558,
"report": "impression: No acute cardiopulmonary process Findings: There is no focal consolidation, effusion, or vascular congestion. The\n cardiomediastinal silhouette is within normal limits. No acute osseous\n abnormalities identified.",
"image_path": [
"p19/p19748558/s53919021/6eaf56a0-ded30052-29edb3ad-20da2133-db0cf728.jpg"
],
"split": "test"
},
{
"id": "f576c221-e516f6b2-ee125faa-a1af8c31-ed2991b8",
"study_id": 50290463,
"subject_id": 10933609,
"report": "impression: 1. Improving right upper lobe consolidation.\n 2. Mild heart failure.\n 3. Findings of chronic lung disease, most likely sarcoidosis. Findings: AP and lateral views of the chest were provided. Lung volumes are\n low, similar to the prior study. The previously noted dense consolidation of\n the right upper lobe has improved with diffuse streaky opacities remaining. \n There are findings consistent with chronic lung disease such as sarcoidosis. \n Prominence of the pulmonary interstitial markings is due to mild heart\n failure. There is no pleural effusion or pneumothorax. The cardiomediastinal\n silhouette is notable for a tortuous aorta. Bones are slightly osteopenic.",
"image_path": [
"p10/p10933609/s50290463/f576c221-e516f6b2-ee125faa-a1af8c31-ed2991b8.jpg"
],
"split": "test"
},
{
"id": "44c09f7b-0aed1234-2a1a02ab-3e91e954-54be38b1",
"study_id": 58606191,
"subject_id": 11880923,
"report": "As compared to the previous radiograph, there is no relevant\n change. Pleural effusions bilaterally, right more than left, the distribution\n of which has changed, but not their overall extent. In the interval, the\n patient has been extubated. The other monitoring and support devices remain\n in place. Unchanged size of the cardiac silhouette. Unchanged mild fluid\n overload.",
"image_path": [
"p11/p11880923/s58606191/44c09f7b-0aed1234-2a1a02ab-3e91e954-54be38b1.jpg"
],
"split": "test"
},
{
"id": "320ec4bc-eb78eb77-b0088c51-9c38d6dc-d4677778",
"study_id": 57884279,
"subject_id": 16334516,
"report": "impression: Dobbhoff tube in nondistended stomach. Findings: Portable semi-erect AP chest radiograph demonstrates a Dobbhoff tube seen\n descending in an uncomplicated course and terminating in the stomach in\n appropriate position. A left internal jugular line is seen at the level of\n the mid to low superior vena cava. There has been interval removal of Swan\n Ganz catheter. There is re- demonstration of left lung consolidations within\n the lower and upper lobe which appear unchanged when compared to chest\n radiograph dated ___. The right lung is grossly unchanged. There\n is no pneumothorax identified. The cardiomediastinal and hilar contours are\n stable in appearance. An IVC filter is identified adjacent to the spine in\n the right mid abdomen.",
"image_path": [
"p16/p16334516/s57884279/320ec4bc-eb78eb77-b0088c51-9c38d6dc-d4677778.jpg"
],
"split": "test"
},
{
"id": "e07fa786-650ff653-81675db1-7d20a8f0-b4a5b8f3",
"study_id": 53183813,
"subject_id": 16508811,
"report": "impression: Large area of consolidation involving the left lung, worrisome for pneumonia. \n Recommend followup to resolution. Possible trace left pleural effusion.\n \n Right base opacity may be due to atelectasis, of additional site infection is\n not excluded in the appropriate clinical setting. Findings: Left-sided consolidation involving the left upper lobes and possibly portions\n of the lingula and left lower lobe is seen. There is a trace left pleural\n effusion. Subtle opacity at the right lung base of is more likely due to\n atelectasis bone additional site of infection is not excluded. Prominence of\n the right hilum is stable. The cardiac and mediastinal silhouettes are\n stable. No pneumothorax is seen.",
"image_path": [
"p16/p16508811/s53183813/e07fa786-650ff653-81675db1-7d20a8f0-b4a5b8f3.jpg"
],
"split": "test"
},
{
"id": "2f9cc5fb-ee49a77d-61586888-9ea3d166-e27de7ba",
"study_id": 52697084,
"subject_id": 19914761,
"report": "In comparison with the study of ___, there is again biapical\n thickening and adjacent pulmonary parenchymal scarring with tortuosity of the\n aorta. Mild elevation of the right hemidiaphragm is again seen.\n \n No evidence of pulmonary vascular congestion or acute focal pneumonia.",
"image_path": [
"p19/p19914761/s52697084/2f9cc5fb-ee49a77d-61586888-9ea3d166-e27de7ba.jpg"
],
"split": "test"
},
{
"id": "6b93ec0b-b35a1d19-cbcefb65-297d04fe-ca31986d",
"study_id": 56051681,
"subject_id": 11924226,
"report": "impression: No signs of pneumonia. Findings: PA and lateral views of the chest provided demonstrate no focal\n consolidation, effusion or pneumothorax. The cardiomediastinal silhouette is\n normal. Bony structures are intact. There is no free air below the right\n hemidiaphragm. Mild degenerative change in the mid thoracic spine noted on\n the lateral projection.",
"image_path": [
"p11/p11924226/s56051681/6b93ec0b-b35a1d19-cbcefb65-297d04fe-ca31986d.jpg"
],
"split": "test"
},
{
"id": "54b17fd5-2b9447fa-49e494d4-99a53410-c2e24e0b",
"study_id": 58679736,
"subject_id": 19623993,
"report": "impression: No acute findings. Findings: No focal consolidation, pleural effusion, pneumothorax, or pulmonary edema is\n seen. Heart size is normal. There is persistent aortic tortuosity. No rib\n fracture is detected, although sensitivity is low on routine chest\n radiography.",
"image_path": [
"p19/p19623993/s58679736/54b17fd5-2b9447fa-49e494d4-99a53410-c2e24e0b.jpg"
],
"split": "test"
},
{
"id": "85817777-b9158c6e-b0d376b5-d21f2744-f3a04234",
"study_id": 57356552,
"subject_id": 19389547,
"report": "Right-sided chest tube remains in place, with slight increase in\n size of a small right pleural effusion, but no visible pneumothorax. \n Bibasilar linear atelectasis has slightly worsened, and there is a persistent\n small left pleural effusion.",
"image_path": [
"p19/p19389547/s57356552/85817777-b9158c6e-b0d376b5-d21f2744-f3a04234.jpg"
],
"split": "test"
},
{
"id": "ce354924-31b789c8-efd39b27-f2708902-84e7f064",
"study_id": 57959841,
"subject_id": 10885696,
"report": "impression: Post left upper lobectomy changes, with no superimposed acute\n intrathoracic process detected. Findings: The patient is status post\n left upper lobectomy, with expected persistent left lung volume loss and shift\n of mediastinal structures. The cardiac, mediastinal, and hilar contours are\n unchanged, allowing for differences in technique and rotation of the patient. \n Biapical scarring is again seen. There is no pneumothorax or new\n consolidation.",
"image_path": [
"p10/p10885696/s57959841/ce354924-31b789c8-efd39b27-f2708902-84e7f064.jpg"
],
"split": "test"
},
{
"id": "c9028d9d-b5be82c7-94f4e115-fcd0cbb2-bdc86018",
"study_id": 53653168,
"subject_id": 16334516,
"report": "impression: 1. Endotracheal and enteric tubes in appropriate position.\n 2. Interval placement of a left-sided IJ central venous catheter terminating\n in the proximal SVC without evidence of pneumothorax.\n 3. Interval development of left base opacity, likely combination of left\n lower lobe collapse and pleural effusion. Increased perihilar opacities\n suggest pulmonary edema. Findings: Enteric tube is seen coursing below the level of the diaphragm,\n coiling in the stomach. There has been interval placement of an endotracheal\n tube, terminating approximately 3 cm above the level of the carina. A\n left-sided internal jugular central venous catheter has also been placed in\n the interval, terminating in the proximal SVC. There has been interval\n development of left lower lobe atelectasis with possible effusion. There is\n also increase in perihilar opacity suggesting pulmonary edema. Scattered\n areas of linear opacity again seen due to scarring/atelectasis. The cardiac\n and mediastinal silhouettes are grossly stable. Again, the patient is status\n post median sternotomy and CABG.",
"image_path": [
"p16/p16334516/s53653168/c9028d9d-b5be82c7-94f4e115-fcd0cbb2-bdc86018.jpg"
],
"split": "test"
},
{
"id": "9d53d4d6-3495e14a-d2f6c5b0-333b5174-8b65e1ab",
"study_id": 58379619,
"subject_id": 12110863,
"report": "impression: 1. Interval improved pulmonary edema. \n \n 2. Mildly increased small left pleural effusion and atelectasis admixed with\n chronic changes in the left lung base. Findings: Frontal lateral views of the chest demonstrate left pectoral cardiac pacer\n with leads terminating in the right atrium and right ventricle. There is\n evidence of prior CABG. Median sternotomy wires are intact. Massive\n cardiomegaly is similar as before. Low lung volumes are unchanged. There is\n interval improvement of previously mild interstitial edema. Streaky\n retrocardiac opacities may be a combination of a chronic changes and\n subsegmental atelectasis. There is likely a small left pleural effusion.",
"image_path": [
"p12/p12110863/s58379619/9d53d4d6-3495e14a-d2f6c5b0-333b5174-8b65e1ab.jpg"
],
"split": "test"
},
{
"id": "ec78e0b4-c858f616-11d4e328-ff8d6f90-4a6acef0",
"study_id": 59885828,
"subject_id": 10933609,
"report": "As compared to the previous radiograph, the lung volumes have\n slightly increased. The pre-existing, predominantly perihilar opacities have\n substantially decreased in extent and severity. The remaining opacities are\n now predominating in the upper lobes and are located around the upper aspects\n of the left and right hilus.\n \n No newly appeared opacities. The left internal jugular vein catheter has been\n removed, the lateral radiograph shows evidence of a small left effusion,\n obliterating the dorsal aspects of the costophrenic sinus.",
"image_path": [
"p10/p10933609/s59885828/ec78e0b4-c858f616-11d4e328-ff8d6f90-4a6acef0.jpg"
],
"split": "test"
},
{
"id": "00791688-1fab1483-c2c6bc65-78567732-ff0cf7cc",
"study_id": 55644325,
"subject_id": 12433421,
"report": "impression: 1. Concern for small left-sided hydropneumothorax of uncertain etiology.\n 2. 13 mm right lower lobe pulmonary nodule. Differential includes nipple\n shadow, osseous lesion, or pulmonary parenchymal nodule. Followup radiographs\n with oblique projections and nipple markers could be considered. \n Alternatively, CT of the chest could also be performed for further\n characterization of the left-sided pleural process and the right lower lobe\n nodule.\n 3. No confluent consolidation or pulmonary edema.\n \n Dr. ___ communicated the above results to Dr. ___ at 6:03 pm\n ___ ___ by telephone. Findings: There is blunting of the left costophrenic\n angle correlating with effusion better appreciated on the lateral projection. \n Additionally, there is an ovoid lucent area in the retrocardiac region on the\n frontal projection seen anteriorly on the lateral projection suggesting a\n hydropneumothorax of uncertain etiology. The left lung appears clear without\n focal nodule, mass, or consolidation. In the right lung base is a small\n nodule measuring 13 mm which may reflect a nipple shadow or alternatively a\n pulmonary parenchymal nodule or osseous lesion. The remainder of the lungs\n appear clear. No overt pulmonary edema or vascular congestion is identified. \n Cardiomediastinal and hilar contours are within normal limits.",
"image_path": [
"p12/p12433421/s55644325/00791688-1fab1483-c2c6bc65-78567732-ff0cf7cc.jpg"
],
"split": "test"
},
{
"id": "2626edcd-3f9f9f05-089bb9fa-c8ba4148-efad5e91",
"study_id": 50319774,
"subject_id": 13473495,
"report": "impression: Pulmonary vascular congestion, slightly worse in the interval. Findings: Severe cardiomegaly persists. A left subclavian vascular stent is re-\n demonstrated. Mediastinal contours are unchanged. There is pulmonary\n vascular congestion,slightly worse in the interval. A small amount of fluid\n is noted within the minor fissure. No focal consolidation, pleural effusion\n or pneumothorax is demonstrated.",
"image_path": [
"p13/p13473495/s50319774/2626edcd-3f9f9f05-089bb9fa-c8ba4148-efad5e91.jpg"
],
"split": "test"
},
{
"id": "036272e9-9052e7c2-444e59fd-86a7f36d-9dfe191a",
"study_id": 58585557,
"subject_id": 12595991,
"report": "impression: 1. Bibasilar consolidations may represent atelectasis or pneumonia in the\n appropriate clinical setting.\n \n 2. New lucency beneath the right hemidiaphragm is concerning for\n intra-abdominal free air. Clinical correlation recommended. Additional\n evaluation could be performed with repeat upright radiograph or left lateral\n decubitus radiograph. Findings: Portable semi-upright radiograph of the chest demonstrates low lung volumes\n with resultant bronchovascular crowding. Bibasilar consolidations may\n represent atelectasis or pneumonia in the appropriate clinical setting. The\n cardiomediastinal and hilar contours are unchanged. There is a new lucency\n beneath the right hemidiaphragm concerning for intra-abdominal free air.\n Right-sided PICC line and to the mid SVC. Unchanged position of the AICD. No\n pneumothorax.",
"image_path": [
"p12/p12595991/s58585557/036272e9-9052e7c2-444e59fd-86a7f36d-9dfe191a.jpg"
],
"split": "test"
},
{
"id": "405581ff-6e5fc337-04c3cddc-f4b5bffe-992dd6f7",
"study_id": 55157144,
"subject_id": 19016834,
"report": "impression: There is no radiologic evidence of new pneumonia. Findings: There is no new consolidation. Right lower lobe pneumonia that was present in\n prior exams has significantly improved. Esophageal stent is in unchanged\n position. There is no pneumomediastinum or pneumothorax. There is no pleural\n effusion. Mediastinal and cardiac contours are stable.",
"image_path": [
"p19/p19016834/s55157144/405581ff-6e5fc337-04c3cddc-f4b5bffe-992dd6f7.jpg"
],
"split": "test"
},
{
"id": "3f80bbda-1c82f45d-788d2535-2c56bc02-94651d15",
"study_id": 50906117,
"subject_id": 14744884,
"report": "impression: No evidence of acute disease. Findings: The cardiac, mediastinal and hilar contours appear unchanged. The\n lungs appear clear. There are no pleural effusions or pneumothorax. A\n vascular stent, presumably within the right brachiocephalic vein, again\n projects over the medial right lung apex.",
"image_path": [
"p14/p14744884/s50906117/3f80bbda-1c82f45d-788d2535-2c56bc02-94651d15.jpg"
],
"split": "test"
},
{
"id": "277f62f5-617ece32-531a87ea-d1f6b703-578157ce",
"study_id": 50112134,
"subject_id": 16553329,
"report": "impression: New HD catheter in place. Prominent perihilar vascular markings with subtle\n nodularity in the left upper lobe requiring CT on a nonemergent basis to\n further assess. Small left pleural effusion with basal atelectasis. Findings: There has been interval placement of a right central dialysis catheter. \n Bilateral hilar vascular prominence is re- demonstrated with subtle nodularity\n in the left upper lung likely representing confluence of vasculature though a\n true nodule difficult to exclude. There is no convincing sign of pneumonia or\n overt edema. Small left effusion is present with basilar atelectasis. The\n cardiomediastinal silhouette is unchanged.",
"image_path": [
"p16/p16553329/s50112134/277f62f5-617ece32-531a87ea-d1f6b703-578157ce.jpg"
],
"split": "test"
},
{
"id": "2b0c69d6-c2dc4934-db59e90a-2e58d454-ee26f72e",
"study_id": 57952807,
"subject_id": 16059470,
"report": "Patient is status post median sternotomy and coronary artery bypass\n surgery. ICD remains in place as well as a right PICC. Cardiac silhouette is\n mildly enlarged, and accompanied by mild pulmonary vascular congestion. \n Persistent patchy right basilar opacity and new patchy left lower lobe opacity\n as well as a persistent linear area of atelectasis in the left lower lobe. \n The etiology of the basilar opacities is uncertain, but could represent\n aspiration, infectious pneumonia, or a dependent distribution of edema in the\n setting of known upper lobe predominant emphysema.",
"image_path": [
"p16/p16059470/s57952807/2b0c69d6-c2dc4934-db59e90a-2e58d454-ee26f72e.jpg"
],
"split": "test"
},
{
"id": "33ecbdf2-35c3aa31-e848a7b9-a49131b4-0690b4a3",
"study_id": 55960520,
"subject_id": 16826047,
"report": "impression: Probable lobar pneumonia involving the right lower lobe and\n possibly the right middle lobe with associated parapneumonic effusion. \n Findings consistent with heart failure.\n \n Findings were communicated by Dr. ___ to Dr. ___ by phone at 11:11 a.m.\n on ___. Findings: There is a large focal consolidation involving the right lower lobe\n which may also involve the right middle lobe with associated moderate pleural\n fluid on the right side, all of which are new findings since the prior study\n ___ ___. There is increased pulmonary vascular engorgement from the prior\n study and the cardiac silhouette is enlarged as seen on the prior study but\n increased in size. No pneumothorax is seen. A right-sided port is unchanged\n in position with the tip terminating in the low SVC. The mediastinal and\n hilar contours are stable.",
"image_path": [
"p16/p16826047/s55960520/33ecbdf2-35c3aa31-e848a7b9-a49131b4-0690b4a3.jpg"
],
"split": "test"
},
{
"id": "ebcd934a-fe1838dd-2918f535-1a7560c9-be5e9ab2",
"study_id": 53412826,
"subject_id": 19150427,
"report": "impression: Right upper lobe pneumonia. Followup radiographs after treatment are\n recommended to ensure resolution of this finding. Findings: The patient is status post median sternotomy, CABG, and vascular stenting.\n Heart is mildly enlarged but stable. The mediastinal and hilar contours are\n similar with mild unfolding of thoracic aorta. New consolidative process is\n noted within the right upper lobe compatible with pneumonia. There is mild\n pulmonary vascular congestion. Small pleural effusion on the right is\n present. No pneumothorax is identified. Degenerative changes involving the\n left glenohumeral and bilateral acromioclavicular joints are noted.",
"image_path": [
"p19/p19150427/s53412826/ebcd934a-fe1838dd-2918f535-1a7560c9-be5e9ab2.jpg"
],
"split": "test"
},
{
"id": "137c9581-82049ac3-2bce7676-8032c119-9845711c",
"study_id": 58317281,
"subject_id": 17669276,
"report": "impression: Small bilateral pleural effusions, mildly increased from prior. Findings: AP upright portable chest radiograph obtained. Midline sternotomy\n wires are again noted. There are tiny bilateral pleural effusions, slightly\n increased from prior exam. There is no definite sign of pneumonia or overt\n CHF. The heart size is stable. Mediastinal contour is widened reflecting an\n unfolded thoracic aorta. No pneumothorax. Bony structures appear intact.",
"image_path": [
"p17/p17669276/s58317281/137c9581-82049ac3-2bce7676-8032c119-9845711c.jpg"
],
"split": "test"
},
{
"id": "13a5d3b6-8cf4d79a-807319e4-1292cd55-39f57349",
"study_id": 53115889,
"subject_id": 17770657,
"report": "In comparison with study of ___, there is little overall change in\n the appearance of the heart and lungs. Continued hyperexpansion without\n evidence of acute focal pneumonia, though there are atelectatic changes at the\n left base.\n \n There is subcutaneous gas along the chest walls bilaterally that was not\n appreciated on the prior study. This information was telephoned to the nurse\n in the ICU taking care of the patient on ___ at 950 upon noticing the\n abnormality.",
"image_path": [
"p17/p17770657/s53115889/13a5d3b6-8cf4d79a-807319e4-1292cd55-39f57349.jpg"
],
"split": "test"
},
{
"id": "c8591b84-dfb9bd0c-54f0a9f4-e5258ccd-4fec4b57",
"study_id": 58324748,
"subject_id": 16855430,
"report": "impression: Limited study due to body habitus. There are low lung volumes\n which result in bronchovascular crowding, but beyond that there is likely\n moderate pulmonary edema presumably cardiogenic in etiology. There may also\n be small bilateral pleural effusions. Findings: As similar to multiple prior exams, there is a relative hazy\n density in the bilateral hilar regions with pulmonary vascular indistinctness.\n The hemidiaphragms are not well defined. The cardiomediastinal silhouette is\n markedly enlarged with widening superiorly and an enlarged cardiac silhouette\n inferiorly. The patient's chin overlies the lung apices, limiting the\n evaluation. No gross pneumothorax is seen.",
"image_path": [
"p16/p16855430/s58324748/c8591b84-dfb9bd0c-54f0a9f4-e5258ccd-4fec4b57.jpg"
],
"split": "test"
},
{
"id": "5037ce6f-1b5a2beb-cefbe169-b7e53cbf-427eaf91",
"study_id": 55339618,
"subject_id": 13475033,
"report": "impression: 1. No acute intrathoracic process. Stable bilateral interstitial markings,\n likely chronic lung disease.\n 2. Coronary artery calcifications. Findings: There are diffuse bilateral interstitial markings, overall unchanged since\n ___. This is consistent with chronic lung disease. No new areas of\n focal consolidation or pleural effusions. No pneumothorax. Heart size is top\n normal, stable from prior. Atherosclerotic calcifications are seen in the\n coronary arteries, better appreciated on the lateral view.",
"image_path": [
"p13/p13475033/s55339618/5037ce6f-1b5a2beb-cefbe169-b7e53cbf-427eaf91.jpg"
],
"split": "test"
},
{
"id": "4c51a119-6f346625-6da3ca60-c048486b-db7e21e6",
"study_id": 55525523,
"subject_id": 11293517,
"report": "impression: No acute findings in the chest. Stable mild cardiomegaly. \n Multiple pacer wires are unchanged in position. Findings: AP upright portable chest radiograph is obtained. A left chest\n wall pacer device is again seen with lead tips extending into the right atrium\n and ventricle. Abandoned pacing leads are also seen in the right chest wall,\n extending into the right heart, not significantly changed. The heart is\n mildly enlarged. The lungs appear clear without definite signs of pneumonia\n or CHF. No large effusion or pneumothorax is seen. The overall\n cardiomediastinal silhouette is stable. Bony structures are intact.",
"image_path": [
"p11/p11293517/s55525523/4c51a119-6f346625-6da3ca60-c048486b-db7e21e6.jpg"
],
"split": "test"
},
{
"id": "1a3a93cb-fcff8a20-d84a6c00-5a46ada4-2a5d437a",
"study_id": 51807934,
"subject_id": 13067703,
"report": "impression: 1. Increased nodular opacity in the medial right apex/right suprahilar region\n underlying fiducial seeds, worrisome for progression of malignancy.\n 2. Bilateral left greater than right pleural effusion, which is likely\n loculated at least on the left.\n 3. Right infrahilar streaky opacity may relate to prior surgery/chronic\n changes but more acute component not excluded. Findings: Frontal and lateral views of the chest were obtained. A dual-lead\n left-sided AICD is again seen with leads extending to the expected positions\n of the right atrium and right ventricle. The right costophrenic angle is not\n fully included on the image. There are bilateral pleural effusions, which may\n be at least partially loculated.\n \n Right upper lobe/suprahilar opacity underlying fiducial seed has increased\n since the prior study, raising concern for progression of malignancy. Streaky\n right infrahilar opacity underlying chain sutures, may relate to chronic\n changes, although appears to have increased since the prior study. The\n cardiac and mediastinal silhouettes are stable.",
"image_path": [
"p13/p13067703/s51807934/1a3a93cb-fcff8a20-d84a6c00-5a46ada4-2a5d437a.jpg"
],
"split": "test"
},
{
"id": "cff0405e-7c684aeb-122051b9-dec202c9-1dfbb41e",
"study_id": 57678258,
"subject_id": 15094735,
"report": "impression: 1. Increasing pulmonary edema and enlargement of the moderate right pleural\n effusion.\n 2. Possible right lower lobe pneumonia is unchanged. Findings: A right internal jugular hemodialysis catheter ends in the right\n atrium. The size of the cardiac silhouette is at the upper limits of normal. \n Sternal wires are intact. A moderate right pleural effusion is slightly\n bigger. There has been slight increase in the pulmonary edema. Opacification\n at the right base persists and may be a pneumonia. There is no pneumothorax.",
"image_path": [
"p15/p15094735/s57678258/cff0405e-7c684aeb-122051b9-dec202c9-1dfbb41e.jpg"
],
"split": "test"
},
{
"id": "b8d216b3-7f16e10d-72147640-2fd8511c-7da23725",
"study_id": 50903895,
"subject_id": 19182863,
"report": "impression: 1. Small right pleural effusion with adjacent right basilar atelectasis.\n \n 2. Cardiomegaly and interstitial edema. Findings: The patient is status post median sternotomy and aortic and\n tricuspid valve surgery. Stable appearance of cardiomediastinal contours. \n Persistent interstitial edema. Patchy and linear bibasilar atelectasis is\n also demonstrated as well as a small right pleural effusion. Left internal\n jugular catheter remains in place within the left superior vena cava.",
"image_path": [
"p19/p19182863/s50903895/b8d216b3-7f16e10d-72147640-2fd8511c-7da23725.jpg"
],
"split": "test"
},
{
"id": "947ce661-ea81059f-7da8d1e6-033e612e-ba93f7fd",
"study_id": 58318333,
"subject_id": 15131736,
"report": "impression: 1. Moderate pulmonary edema with stable moderate cardiomegaly and increased\n small left pleural effusion.\n 2. In order to exclude pneumonia a repeat PA and lateral chest radiograph\n once the edema has resolved should be considered as current underlying\n parenchymal disease limits evaluation.\n 3. A right PICC tip is seen at least up to the low SVC. Findings: The lungs are hypoinflated with crowding of vasculature. There is progression\n of severe vascular engorgement with peribronchial cuffing as well as bilateral\n perihilar opacities with interval increase in small left pleural effusion. No\n right pleural effusion. No pneumothorax. Moderate cardiomegaly is stable.\n \n A right PICC tip is seen at least up to the low SVC.",
"image_path": [
"p15/p15131736/s58318333/947ce661-ea81059f-7da8d1e6-033e612e-ba93f7fd.jpg"
],
"split": "test"
},
{
"id": "ef578547-4e4219db-c1753821-922ec956-1d6e6770",
"study_id": 58406467,
"subject_id": 18906643,
"report": "impression: NG tube extends below the diaphragm into the fundus of the stomach. Findings: The NG tube extends inferiorly beyond the diaphragm into the fundus\n of the stomach. Again seen is moderate cardiomegaly. The pulmonary vascular\n congestion is stable. There are no new focal consolidations. The fissural\n loculation of pleural fluid along the left chest wall has not changed compared\n to the prior exam. There is no pneumothorax.",
"image_path": [
"p18/p18906643/s58406467/ef578547-4e4219db-c1753821-922ec956-1d6e6770.jpg"
],
"split": "test"
},
{
"id": "c1badb19-12851ca1-44ca7736-fc1a9f08-bd287f01",
"study_id": 59735543,
"subject_id": 12475198,
"report": "impression: ICD leads end in the right atrium and right ventricle. No evidence of bleeding\n or pneumothorax. Findings: Frontal and lateral views of the chest demonstrate a transsubclavian right\n atrial and ventricular pacer defibrillator leads in standard position with no\n pneumothorax, pleural effusion, or mediastinal widening. Lung volumes remain\n low. The heart is stably enlarged.",
"image_path": [
"p12/p12475198/s59735543/c1badb19-12851ca1-44ca7736-fc1a9f08-bd287f01.jpg"
],
"split": "test"
},
{
"id": "f0a48678-0a70e80e-79ea26dd-2a4ca8bb-03aaebc1",
"study_id": 59507972,
"subject_id": 13067703,
"report": "impression: 1. Stable small loculated left and small right pleural effusions.\n 2. Heterogeneous opacity in the left lower lobe may be representative of\n developing pneumonia in the appropriate clinical setting. Findings: Dual-lead left-sided pacemaker terminates with leads in the proper\n position. Chain sutures along the right lung base are again noted and appear\n stable.\n \n Again visualized is a loculated small left pleural effusion as well as a small\n right pleural effusion, appearing stable in comparison to prior study. There\n is a new confluent patchy opacity in left lower lobe in comparison to the\n prior study, which may be representative of developing pneumonia. Otherwise,\n the remainder of the lungs is clear. The cardiomediastinal silhouette remains\n stable. The visualized osseous structures are stable.",
"image_path": [
"p13/p13067703/s59507972/f0a48678-0a70e80e-79ea26dd-2a4ca8bb-03aaebc1.jpg"
],
"split": "test"
},
{
"id": "b7013a8b-6c5dab19-f07b823e-d65d3507-a7548d2f",
"study_id": 57120452,
"subject_id": 14744884,
"report": "impression: Stable mild pulmonary vascular congestion and mild cardiomegaly. Findings: Lung volumes are slightly low, as before, with persistent mild pulmonary\n vascular congestion and mild cardiomegaly. No focal consolidation concerning\n for pneumonia is identified. There is no pneumothorax. A metallic right\n subclavian vein stent is unchanged.",
"image_path": [
"p14/p14744884/s57120452/b7013a8b-6c5dab19-f07b823e-d65d3507-a7548d2f.jpg"
],
"split": "test"
},
{
"id": "2094ddf3-2348835f-2f468a2c-493f4e64-1b4ef954",
"study_id": 53060980,
"subject_id": 16553329,
"report": "impression: No acute cardiopulmonary abnormality. Findings: The heart size is normal. Mediastinal and hilar contours are unremarkable. \n The pulmonary vascularity is within normal limits. Scattered calcifications\n within the upper lung fields bilaterally likely reflect the sequela of prior\n granulomatous disease. No focal consolidation, pleural effusion or\n pneumothorax is seen. There is likely minimal retrocardiac atelectasis. No\n acute osseous abnormalities are demonstrated. There are mild degenerative\n changes of the thoracic spine as well as within the imaged left AC joint.",
"image_path": [
"p16/p16553329/s53060980/2094ddf3-2348835f-2f468a2c-493f4e64-1b4ef954.jpg"
],
"split": "test"
},
{
"id": "af39d55c-0622bc39-b9865798-29ff5a61-eb7cfb93",
"study_id": 52874646,
"subject_id": 12074041,
"report": "impression: New left basilar opacity worrisome for pneumonia. Findings: The cardiac, mediastinal, and hilar contours appear unchanged. The\n lung volumes are low. There is a patchy left basilar opacity obscuring the\n cardiac border and apex of the left hemidiaphragm, worrisome for pneumonia. \n Elsewhere, the lungs appear clear. There are no pleural effusions or\n pneumothorax.",
"image_path": [
"p12/p12074041/s52874646/af39d55c-0622bc39-b9865798-29ff5a61-eb7cfb93.jpg"
],
"split": "test"
},
{
"id": "9c67a2e3-68620391-2e5a5578-0433f757-1eba00c6",
"study_id": 56233609,
"subject_id": 18767957,
"report": "impression: No significant interval change. Findings: There has been no significant interval change. The cardiac and mediastinal\n silhouettes are stable. Hilar contours are stable with possible minimal\n central vascular engorgement.",
"image_path": [
"p18/p18767957/s56233609/9c67a2e3-68620391-2e5a5578-0433f757-1eba00c6.jpg"
],
"split": "test"
},
{
"id": "4b64a5b1-add48a29-703a757c-e888cd6b-4684205e",
"study_id": 51293673,
"subject_id": 16435402,
"report": "impression: Rounded opacity in the left mid lung field, possibly reflecting an area of\n infection. Findings: Heart size is normal. Mediastinal and hilar contours are unremarkable. \n Pulmonary vascularity is normal. Nodular area of opacification in the left\n mid lung field was not clearly demonstrated on the prior radiograph. No other\n areas of focal consolidation, pleural effusion or pneumothorax are\n demonstrated. Healed fracture of the left 8th rib is seen, superior to the\n left nipple shadow. Numerous radiopaque circular ovoid structures are seen\n within the upper abdomen, likely reflecting ingested pills within the bowel. \n Clips are noted in the upper abdomen related to prior cholecystectomy.",
"image_path": [
"p16/p16435402/s51293673/4b64a5b1-add48a29-703a757c-e888cd6b-4684205e.jpg"
],
"split": "test"
},
{
"id": "38c65a6d-f4aef98f-d9b4f8fc-37878bd1-8cf123a6",
"study_id": 57273388,
"subject_id": 18338007,
"report": "impression: Limited examination due to extremely low lung volumes. Elevated\n left diaphragm is unchanged. No definite acute intrathoracic process. Findings: The lungs are extremely low in volume but appear\n clear. The cardiac silhouette is obscured by an elevated left hemidiaphragm,\n unchanged. The hilar contours and pleural surfaces appear normal. No\n definite pleural effusions are present.",
"image_path": [
"p18/p18338007/s57273388/38c65a6d-f4aef98f-d9b4f8fc-37878bd1-8cf123a6.jpg"
],
"split": "test"
},
{
"id": "32a7d189-41a4b4a2-2cbe2e58-67f6823b-94d7cb9b",
"study_id": 57053848,
"subject_id": 12658295,
"report": "In comparison with study of ___, there has been reaccumulation of\n pleural fluid at the right base with underlying compressive atelectasis\n following apparent thoracentesis. No evidence of pneumothorax. The remainder\n of the heart and lungs are unchanged.",
"image_path": [
"p12/p12658295/s57053848/32a7d189-41a4b4a2-2cbe2e58-67f6823b-94d7cb9b.jpg"
],
"split": "test"
},
{
"id": "3478fd3c-a34b3e6d-0a9a1cf3-726cb9cd-ec1381aa",
"study_id": 57752575,
"subject_id": 16672854,
"report": "impression: Mild pulmonary vascular congestion and retrocardiac atelectasis. Findings: The patient is status post median sternotomy and CABG. The heart size remains\n moderately enlarged. The mediastinal contour is unremarkable and unchanged. \n Mild pulmonary vascular congestion is improved compared to the previous exam. \n Retrocardiac streaky opacity likely reflects atelectasis. Blunting of the\n right costophrenic sulcus suggests that there may be a trace pleural effusion.\n No pneumothorax is identified. Degenerative changes of the right glenohumeral\n joint with joint space narrowing and osteophytic spurring is present.",
"image_path": [
"p16/p16672854/s57752575/3478fd3c-a34b3e6d-0a9a1cf3-726cb9cd-ec1381aa.jpg"
],
"split": "test"
},
{
"id": "d5fa9e5f-25744b5d-edd68a9c-806bfe8e-e7e0b542",
"study_id": 54844091,
"subject_id": 16855430,
"report": "impression: Increased left basilar and right upper lung opacity could reflect\n developing pneumonia in the proper clinical setting. Findings: There is increased opacity at the left lung base, with associated volume loss.\n This could represent worsening of effusion and atelectasis, though developing\n pneumonia cannot be excluded. Additional increasec opacity in the right\n suprahilar region may reflect additional focus of airspace disease. \n Elsewhere, the lungs remain well aerated. A small amount of right pleural\n fluid is present. Heart size is persistenly enalrged. There is pulmonary\n vascular engorgement without frank edema, which is little changed from prior\n study.",
"image_path": [
"p16/p16855430/s54844091/d5fa9e5f-25744b5d-edd68a9c-806bfe8e-e7e0b542.jpg"
],
"split": "test"
},
{
"id": "d122eb74-bc404dd2-45a05cd3-18505b72-5058fbdd",
"study_id": 59381316,
"subject_id": 19991135,
"report": "PA and lateral chest views were obtained with patient in upright\n position. Comparison is made with the next preceding similar study obtained\n four hours earlier during the same day. The previously described right-sided\n chest tube remains in unchanged position. No pneumothorax has developed and\n there is no evidence of significantly increased pleural densities during this\n interval. The right-sided chest wall emphysema described earlier has\n regressed. No new abnormalities are seen. Left-sided hemithorax is\n unremarkable.",
"image_path": [
"p19/p19991135/s59381316/d122eb74-bc404dd2-45a05cd3-18505b72-5058fbdd.jpg"
],
"split": "test"
},
{
"id": "e2639104-28411e18-bfafdd6f-8f7fed3a-0801198b",
"study_id": 55610892,
"subject_id": 13473495,
"report": "impression: Pulmonary edema is slightly worse than on recent exam. Findings: Low lung volumes are again noted. There are however persistently increased\n interstitial markings which appear slightly progressed compared to prior. \n There is no pleural effusion. The cardiac silhouette is enlarged, as on prior.\n Left subclavian stent is again seen.",
"image_path": [
"p13/p13473495/s55610892/e2639104-28411e18-bfafdd6f-8f7fed3a-0801198b.jpg"
],
"split": "test"
},
{
"id": "7e1f323f-a2ad8df6-c4803950-58e8a9d6-7058b48e",
"study_id": 54729238,
"subject_id": 12433541,
"report": "impression: 1. Large right hilar lung mass and radiation fibrosis. Additional\n post-obstructive pneumonia in the right upper and lower lobes is possible but\n hard to delineate.\n 2. New left retrocardiac opacity, small left effusion, and pleural\n thickening.\n \n Findings were discussed with ___, RN, via telephone at ___ and\n again with Dr ___ at ___. Findings: An extensive right hilar lung mass is associated with radiation\n fibrosis, better delineated on CT ___. An additional component of\n postobstructive pneumonia may be present. Retrocardiac opacity, left pleural\n effusion, and left plueral thickening are also new. No pneumothorax is\n present.",
"image_path": [
"p12/p12433541/s54729238/7e1f323f-a2ad8df6-c4803950-58e8a9d6-7058b48e.jpg"
],
"split": "test"
},
{
"id": "acddfc4f-6bf56983-900fa34f-f650d62f-a30c95af",
"study_id": 53418217,
"subject_id": 17763117,
"report": "impression: Pulmonary vascular engorgement without overt pulmonary edema. No\n pneumonia. Findings: Frontal AP and lateral views of the chest were obtained. The\n patient is rotated. The left pectoral ICD leads end in the expected locations\n of the right atrium and right ventricle. The patient is status post median\n sternotomy with intact wires. A right PICC ends in the upper SVC. There is no\n focal consolidation, pleural effusion or pneumothorax. Opacity at the right\n cardiophrenic angle corresponds to mediastinal fat on CT ___. Aortic\n knob calcifications are noted. There is pulmonary vascular engorgement and\n mild cardiomegaly. \n \n A nodule in the right upper lung is not well visualized on this study and is\n better evaluated on chest CT ___. Multiple calcified granulomas are\n noted.",
"image_path": [
"p17/p17763117/s53418217/acddfc4f-6bf56983-900fa34f-f650d62f-a30c95af.jpg"
],
"split": "test"
},
{
"id": "614cf968-41dc136f-73eb6d42-6b73032b-e0dde637",
"study_id": 57420525,
"subject_id": 17257913,
"report": "impression: Stable chest findings, no evidence of pulmonary congestion or\n acute parenchymal infiltrates in this patient with history of cough. Findings: PA and lateral chest views were obtained with patient in upright\n position. Analysis is performed in direct comparison with the next preceding\n chest examination of ___. Heart size is normal. Relatively\n wide mediastinal and cardiac contours are compatible with previously on CT\n documented mediastinal lipomatosis. Accessible aortic contours are\n unremarkable. The pulmonary vasculature is not congested. No signs of acute\n or chronic parenchymal infiltrates are present and the lateral and posterior\n pleural sinuses are free. Skeletal structures of the thorax grossly\n unremarkable. In comparison with the next preceding study, no significant\n interval change can be identified. Prominence of soft tissue structures\n surrounding the skeletal structures of the thorax are indicative of rather\n advanced adiposity.",
"image_path": [
"p17/p17257913/s57420525/614cf968-41dc136f-73eb6d42-6b73032b-e0dde637.jpg"
],
"split": "test"
},
{
"id": "c6264595-96860b66-fd1dfa5b-4697f3ba-214d913a",
"study_id": 52481248,
"subject_id": 13979643,
"report": "impression: Mild pulmonary vascular congestion and small left pleural\n effusion. Mild bibasilar atelectasis. Findings: There are low lung volumes. The heart\n size is mildly enlarged. The aorta is unfolded. There is mild pulmonary\n vascular congestion, with small amount of fluid seen within the fissures. \n Additionally, patchy opacities in the lung bases likely reflect atelectasis. \n A small left pleural effusion is relatively unchanged compared to prior. No\n new areas of focal consolidation are present. There is no pneumothorax.",
"image_path": [
"p13/p13979643/s52481248/c6264595-96860b66-fd1dfa5b-4697f3ba-214d913a.jpg"
],
"split": "test"
},
{
"id": "5d38b235-8992ecec-2b630078-d290f396-00fdf5db",
"study_id": 53595850,
"subject_id": 15114531,
"report": "impression: No acute cardiopulmonary abnormality. Of note, the patchy opacity within the\n right lower lobe seen on prior CT is not visualized on the current radiograph. Findings: Cardiac, mediastinal and hilar contours are normal. Pulmonary vasculature is\n normal. Lungs appear clear. The previously noted patchy opacity within the\n right lower lobe seen on CT is not well visualized on the current exam. No\n pleural effusion or pneumothorax is present. Cervical spinal fusion hardware\n is partially imaged. Several clips are noted within the left upper quadrant of\n the abdomen.",
"image_path": [
"p15/p15114531/s53595850/5d38b235-8992ecec-2b630078-d290f396-00fdf5db.jpg"
],
"split": "test"
},
{
"id": "93681764-ec39480e-0518b12c-199850c2-f15118ab",
"study_id": 52312858,
"subject_id": 19454978,
"report": "Comparison is made to the prior study from ___ at\n 4:16 a.m.\n \n There has been removal of the endotracheal tube. There is a right-sided IJ\n catheter with distal lead tip at the cavoatrial junction. There is again seen\n some volume loss on the left side. There are no pneumothoraces. There is\n likely a left-sided pleural effusion as well as atelectasis. This is stable\n from the prior study.",
"image_path": [
"p19/p19454978/s52312858/93681764-ec39480e-0518b12c-199850c2-f15118ab.jpg"
],
"split": "test"
},
{
"id": "f461329d-d6c1fb63-1dbb6294-4837e58c-53a0b617",
"study_id": 53157312,
"subject_id": 18906643,
"report": "As compared to the previous radiograph, the patient has received a\n right internal jugular vein catheter. The course of the catheter is\n unremarkable, the tip of the catheter projects over the mid SVC. There is no\n evidence of pneumothorax or other complication.\n \n In the interval, mild pulmonary edema has developed. The known opacity at the\n lateral aspects of the left hemithorax is constant. Constant position of the\n nasogastric tube and of the sternal wires. At the time of observation and\n dictation, 8:54 a.m., the referring physician ___. ___ was paged for\n notification.",
"image_path": [
"p18/p18906643/s53157312/f461329d-d6c1fb63-1dbb6294-4837e58c-53a0b617.jpg"
],
"split": "test"
},
{
"id": "9b4fdd07-1f45d8dc-4890ea49-e3f06306-639cb645",
"study_id": 59032183,
"subject_id": 11052273,
"report": "impression: No acute intrathoracic process. Findings: PA and lateral views of the chest provided. There is no focal consolidation,\n effusion, or pneumothorax. The cardiomediastinal silhouette is stable and\n top-normal in size. Imaged osseous structures are intact. No free air below\n the right hemidiaphragm is seen.",
"image_path": [
"p11/p11052273/s59032183/9b4fdd07-1f45d8dc-4890ea49-e3f06306-639cb645.jpg"
],
"split": "test"
},
{
"id": "6b1b1903-9f343a6b-fe4ba346-dbe5a6fb-63338c26",
"study_id": 52399735,
"subject_id": 13263843,
"report": "As compared to the previous radiograph, the lateral images show\n that the right pleural effusion does not layer, which would be consistent with\n loculation. Also, there is an increase in adjacent atelectasis.",
"image_path": [
"p13/p13263843/s52399735/6b1b1903-9f343a6b-fe4ba346-dbe5a6fb-63338c26.jpg"
],
"split": "test"
},
{
"id": "8385af08-8516e6ef-1401e3b8-75199f0d-5e5877e1",
"study_id": 55983006,
"subject_id": 14312560,
"report": "impression: No acute cardiopulmonary process. Findings: No focal consolidation is seen there is no pleural effusion or pneumothorax.\n The cardiac and mediastinal silhouettes are unremarkable.",
"image_path": [
"p14/p14312560/s55983006/8385af08-8516e6ef-1401e3b8-75199f0d-5e5877e1.jpg"
],
"split": "test"
},
{
"id": "20cbc0cc-b3c8cc7c-20ac42e1-24561590-cdc9f748",
"study_id": 50296389,
"subject_id": 14387068,
"report": "impression: Improving right hydropneumothorax with right lower lung\n opacifications, atelectasis versus edema are likely. Findings: There is a decreased though persistent right-sided\n hydropneumothorax with interval incomplete reexpansion of the right lung. No\n significant mediastinal shift identified with unremarkable mediastinal, hilar,\n and cardiac contours. Right lower lung opacifications may reflect combination\n of reexpansion edema and atelectasis. Minimal left lung atelectasis noted.",
"image_path": [
"p14/p14387068/s50296389/20cbc0cc-b3c8cc7c-20ac42e1-24561590-cdc9f748.jpg"
],
"split": "test"
},
{
"id": "a7b100cd-08c2be2d-a32c2dac-020c1d75-1bd5b887",
"study_id": 55124994,
"subject_id": 11906222,
"report": "As compared to the previous examination, the patient has been\n intubated. The tip of the endotracheal tube projects 3.7 cm above the carina.\n The patient also has received a nasogastric tube, the course of the tube is\n unremarkable, the tip of the tube does not display on the image.\n \n The ventriculoperitoneal shunt and the left subclavian access line are\n unchanged.\n \n There is no evidence of complications, notably no pneumothorax. The lung\n volumes are increased, with subsequent decrease in severity and extent of a\n pre-existing right basal medial parenchymal opacity. No newly appeared\n parenchymal opacities, unchanged size of the cardiac silhouette. No pleural\n effusions.",
"image_path": [
"p11/p11906222/s55124994/a7b100cd-08c2be2d-a32c2dac-020c1d75-1bd5b887.jpg"
],
"split": "test"
},
{
"id": "456d62e4-2e673ffe-83ccc42f-f942c7fb-d5dbc58b",
"study_id": 58773579,
"subject_id": 11540283,
"report": "impression: Mild cardiomegaly without superimposed acute cardiopulmonary process. Findings: The lungs are clear without focal consolidation, effusion, or edema. Left\n chest wall single lead pacing device is noted. Mild cardiomegaly is noted.\n Median sternotomy wires and mediastinal clips are seen. Prior endotracheal and\n enteric tubes are no longer visualized.",
"image_path": [
"p11/p11540283/s58773579/456d62e4-2e673ffe-83ccc42f-f942c7fb-d5dbc58b.jpg"
],
"split": "test"
},
{
"id": "74ab0576-165250aa-5fedc1a0-3f75f2c6-9f87fa70",
"study_id": 56031350,
"subject_id": 10410641,
"report": "impression: Stable large right pleural effusion and increasing left pleural effusion. \n Feasibility of of thoracentesis would best be evaluated with decubitus films. \n Ultrasound guidance can also be considered. Findings: There is a right pleural effusion, the size of which is difficult\n to ascertain. There is unchanged bilateral lower lobe and right middle lobe\n collapse. The small left pleural effusion is unchanged. There is no\n pulmonary vascular congestion or pneumothorax. The cardiac and mediastinal\n contours are not well visualized.",
"image_path": [
"p10/p10410641/s56031350/74ab0576-165250aa-5fedc1a0-3f75f2c6-9f87fa70.jpg"
],
"split": "test"
},
{
"id": "d7e9f055-751c8d65-66226fcf-da86917c-6f5082a5",
"study_id": 51592807,
"subject_id": 12952223,
"report": "Lung volumes are lower than on the prior study with volume loss in\n both lower lobes and bilateral pleural effusions, right greater than left. \n Underlying infectious infiltrate in the lower lobes cannot be excluded. \n Compared to the prior study, the pulmonary appearance in the lower lobes is\n worsened. Right-sided PICC line tip is in the SVC. There is no pneumothorax.",
"image_path": [
"p12/p12952223/s51592807/d7e9f055-751c8d65-66226fcf-da86917c-6f5082a5.jpg"
],
"split": "test"
},
{
"id": "010af5dc-c4d6194d-4922ccd6-543af1d7-30fa1a21",
"study_id": 56790426,
"subject_id": 15659181,
"report": "impression: Because the abnormal appearance of the right middle lobe is seen only on the\n frontal view, if clinical findings warrant suspicion of early pneumonia,\n follow up chest radiographs should be obtained. Findings: The heart size is normal. The hilar and mediastinal contours are\n normal. Obscuration of the right heart border would ordinarily suggest right\n middle lobe pneumonia, but there is no corresponding abnormality on the\n lateral view, and lungs are otherwise clear. There is no pleural effusion or\n pneumothorax.",
"image_path": [
"p15/p15659181/s56790426/010af5dc-c4d6194d-4922ccd6-543af1d7-30fa1a21.jpg"
],
"split": "test"
},
{
"id": "b50c5a50-2713d6bf-b6a084a7-d2b96375-54cc29d2",
"study_id": 52258598,
"subject_id": 15393401,
"report": "As compared to the previous radiograph, the patient is intubated. \n The tip of the endotracheal tube projects approximately 6 cm above the carina.\n The patient also has a nasogastric tube, the tube could be slightly advanced,\n given that the sidehole is at the level of the gastroesophageal junction.\n \n No evidence of complications, notably no pneumothorax.\n \n As compared to the previous image, the size of the cardiac silhouette remains\n moderately enlarged and signs of mild-to-moderate pulmonary edema are seen. A\n right and left pleural effusion with subsequent areas of atelectasis has newly\n developed. No other parenchymal changes.",
"image_path": [
"p15/p15393401/s52258598/b50c5a50-2713d6bf-b6a084a7-d2b96375-54cc29d2.jpg"
],
"split": "test"
},
{
"id": "09c510a6-55f47c1d-504f429b-f333cf7f-7ccf6ac6",
"study_id": 57141526,
"subject_id": 17206933,
"report": "Frontal radiograhs shows diffuse bilateral lung opacities, most\n pronounced in the left upper lobe in the perihilar region likely due to CHF,\n less likely multifocal PNA. Postdiuresis films should be obtained. Left\n retrocardiac opacity likely represents atelectasis.",
"image_path": [
"p17/p17206933/s57141526/09c510a6-55f47c1d-504f429b-f333cf7f-7ccf6ac6.jpg"
],
"split": "test"
},
{
"id": "ffd311aa-b1ad24f7-29b178ef-4423264a-d0298e46",
"study_id": 52365850,
"subject_id": 14841168,
"report": "As compared to the previous radiograph, there is no relevant\n change. Unchanged monitoring and support devices. Unchanged moderate\n cardiomegaly with signs of mild fluid overload. Left and right basal\n atelectasis. Potential small-to-moderate right pleural effusion. No left\n pleural effusion. No interval appearance of new parenchymal opacities.",
"image_path": [
"p14/p14841168/s52365850/ffd311aa-b1ad24f7-29b178ef-4423264a-d0298e46.jpg"
],
"split": "test"
},
{
"id": "234b22c4-55fb91a9-44f7a42f-b764d462-018d3bb9",
"study_id": 50323020,
"subject_id": 12136799,
"report": "impression: No acute cardiopulmonary process. No visualized free air. Findings: Single portable AP view of the chest is compared to previous exam\n from ___. The lungs are clear of focal consolidation. There\n is, however, persistent blunting of the right costophrenic angle, potentially\n due to pleural thickening especially in the setting of multiple prior healed\n right rib fractures. Cardiomediastinal silhouette is stable. No visualized\n free air below the diaphragm.",
"image_path": [
"p12/p12136799/s50323020/234b22c4-55fb91a9-44f7a42f-b764d462-018d3bb9.jpg"
],
"split": "test"
},
{
"id": "4bc65291-c131317d-d5517a48-0f7151d2-cd115f55",
"study_id": 57161577,
"subject_id": 16562430,
"report": "In comparison with the study of ___, the patient has taken a\n slightly better inspiration. Diffuse interstitial prominence persists in this\n patient with enlargement of the cardiac silhouette, most likely representing a\n combination of underlying pulmonary fibrosis and elevated pulmonary venous\n pressure. In the appropriate setting, the possibility of supervening\n pneumonia would be difficult to exclude given the substrate of diffuse\n pulmonary disease.",
"image_path": [
"p16/p16562430/s57161577/4bc65291-c131317d-d5517a48-0f7151d2-cd115f55.jpg"
],
"split": "test"
},
{
"id": "a8ad38e3-9a288818-536ed867-e22718fb-0d0833f5",
"study_id": 55108847,
"subject_id": 11413236,
"report": "impression: Persistent left basilar opacification, suspected to represent\n primarily atelectasis. However, the possibility of superimposed pneumonia\n could be considered in the appropriate clinical setting versus increased\n atelectasis associated with low lung volumes. Findings: The patient is status post sternotomy. A Port-A-Cath terminates at\n the cavoatrial junction. The heart is at the upper limits of normal size. A\n calcified lymph node is seen along the aortopulmonary window. The cardiac,\n mediastinal and hilar contours do not appear significantly changed. The lung\n volumes are low. There is persistent patchy opacification in the left lower\n lobe, which appears somewhat more dense and compressed, perhaps coinciding\n with differences in lung volumes rather than a true interval change however. \n In fact, left basilar opacities are more similar to ___, where\n lungs volumes were somewhat lower than on the more recent prior examination. \n There is no pleural effusion or pneumothorax. Bony structures are\n unremarkable.",
"image_path": [
"p11/p11413236/s55108847/a8ad38e3-9a288818-536ed867-e22718fb-0d0833f5.jpg"
],
"split": "test"
},
{
"id": "643571eb-5685abe0-5b2f161d-df5ebefa-6f160c6f",
"study_id": 55594849,
"subject_id": 19890786,
"report": "In comparison with the study of ___, there again are innumerable\n metastatic nodules involving both lungs with consolidative process involving\n the right lower lung, associated with pleural effusions. It would be\n impossible to exclude the possibility of superimposed pneumonia given the\n extensive underlying lung disease.\n \n The known metastatic lesions involving the inferior scapula and nondisplaced\n fracture of the right posterior eighth rib are not identified on this study.",
"image_path": [
"p19/p19890786/s55594849/643571eb-5685abe0-5b2f161d-df5ebefa-6f160c6f.jpg"
],
"split": "test"
},
{
"id": "d918062a-d0a7bedc-45270789-08ad2dec-e2c2ca87",
"study_id": 55421522,
"subject_id": 15144601,
"report": "impression: No acute cardiopulmonary process. Stable mild cardiomegaly. Findings: Transvenous right atrial and right ventricular pacer leads appear\n in standard placement. Cardiomediastinal silhouette remains mildly enlarged\n but stable. The aorta appears somewhat tortuous with atherosclerotic\n calcifications. The lungs are clear with no evidence of consolidation,\n effusion, or pneumothorax. Median sternotomy wires appear aligned and intact.\n No acute fractures are identified. Mild bilateral acromio-clavicular\n degenerative changes are noted.",
"image_path": [
"p15/p15144601/s55421522/d918062a-d0a7bedc-45270789-08ad2dec-e2c2ca87.jpg"
],
"split": "test"
},
{
"id": "ec2613ac-d859c02c-90a0d8c7-09a107c4-990690ec",
"study_id": 56776331,
"subject_id": 16662264,
"report": "impression: Hazy bibasilar opacities, likely the residua from recent prior\n infection greatly improved in appearance. No new focal consolidation. Findings: Cardiomediastinal silhouette and hilar contours are unremarkable. \n Residual hazy opacities persist at bilateral lung bases and inferior lingula\n from prior recent infection but are significantly improved from prior study. \n There is no pleural effusion or pneumothorax. There is no new focal\n consolidation. The osseous structures are grossly unremarkable.",
"image_path": [
"p16/p16662264/s56776331/ec2613ac-d859c02c-90a0d8c7-09a107c4-990690ec.jpg"
],
"split": "test"
},
{
"id": "646e6ad9-a96531b8-9c145524-8d9eee31-45c942db",
"study_id": 51229730,
"subject_id": 16553329,
"report": "impression: No acute cardiopulmonary process. Findings: Frontal and lateral views of the chest are obtained. Multiple\n calcified granulomas are noted throughout the lungs bilaterally and, unchanged\n since the prior study. No focal consolidation, pleural effusion, or evidence\n of pneumothorax is seen. The cardiac and mediastinal silhouettes are stable\n and unremarkable. Degenerative changes are again seen along the spine.",
"image_path": [
"p16/p16553329/s51229730/646e6ad9-a96531b8-9c145524-8d9eee31-45c942db.jpg"
],
"split": "test"
},
{
"id": "a7fdae9e-97d1a4d6-df3c7f40-29a51d88-39463d76",
"study_id": 57959841,
"subject_id": 10885696,
"report": "impression: Post left upper lobectomy changes, with no superimposed acute\n intrathoracic process detected. Findings: The patient is status post\n left upper lobectomy, with expected persistent left lung volume loss and shift\n of mediastinal structures. The cardiac, mediastinal, and hilar contours are\n unchanged, allowing for differences in technique and rotation of the patient. \n Biapical scarring is again seen. There is no pneumothorax or new\n consolidation.",
"image_path": [
"p10/p10885696/s57959841/a7fdae9e-97d1a4d6-df3c7f40-29a51d88-39463d76.jpg"
],
"split": "test"
},
{
"id": "89a623b8-0f8a2cb9-e027aaf4-7b5828f4-9480d3a6",
"study_id": 54399607,
"subject_id": 18570152,
"report": "impression: Mild pulmonary edema and small right pleural effusion which is improved as\n compared to chest x-ray ___. Findings: A left pectoral pacemaker is noted with a single intact lead. Mild pulmonary\n edema is improved from chest x-ray ___. There is a small right pleural\n effusion. There is no lobar consolidation or pneumothorax.\n \n The heart is mildly enlarged. The mediastinal borders and hilar structures\n are normal.",
"image_path": [
"p18/p18570152/s54399607/89a623b8-0f8a2cb9-e027aaf4-7b5828f4-9480d3a6.jpg"
],
"split": "test"
},
{
"id": "f2029c31-2acb877f-a7000d23-c119d2f1-b5d4844b",
"study_id": 57372388,
"subject_id": 15809646,
"report": "impression: 1. Recurrent rounded atelectasis in the left mid lung as seen on the prior CT\n of ___. \n 2. Asbestos related lung disease. \n 3. Hazy opacification of the bilateral lungs may represent mild pulmonary\n edema. Findings: There is an irregular rounded opacity in the left mid lung zone,\n which was previously seen on ___ and ___ and thought to represent an\n area of round atelectasis which has resolved in the interim and recurred. \n Bilateral pleural plaques and pleural thickening is unchanged from prior\n studies. Increased hazy opacification of the lungs may represent mild\n pulmonary edema. No pleural effusion or pneumothorax is detected. The cardiac\n silhouette is mildly enlarged but stable. Prominence of the mediastinum is\n unchanged with tortuosity of the thoracic aorta. The lungs remain\n hyperinflated suggesting COPD.",
"image_path": [
"p15/p15809646/s57372388/f2029c31-2acb877f-a7000d23-c119d2f1-b5d4844b.jpg"
],
"split": "test"
},
{
"id": "032b9a1a-f727fa4f-786f80a0-cdbfe259-f1a9f763",
"study_id": 55418359,
"subject_id": 15380734,
"report": "impression: Increased left pleural effusion and pulmonary edema. Left lung\n opacity most likely represents atelectasis, although an early developing\n infiltrate cannot be entirely excluded. Recommend repeat radiographs after\n diuresis to rule out underlying infectious process. Findings: AP and lateral views of the chest were provided. There is a\n moderate left pleural effusion, increased since the prior exam. There is a\n stable small right pleural effusion. The pulmonary vasculature is prominent\n consistent with pulmonary edema. Opacity in the left lung most likely\n represents atelectasis. The heart size is top normal and there are aortic knob\n calcifications. There is no pneumothorax.",
"image_path": [
"p15/p15380734/s55418359/032b9a1a-f727fa4f-786f80a0-cdbfe259-f1a9f763.jpg"
],
"split": "test"
},
{
"id": "4b21950a-5565f60b-5e86b9fd-fde33a71-2a564240",
"study_id": 55452685,
"subject_id": 18224196,
"report": "impression: 1. Stable moderate bilateral pleural effusions.\n 2. Resolution of pulmonary edema. Findings: Moderate bilateral pleural effusions, larger on the right than on\n the left, are unchanged. The previously noted pulmonary edema has resolved. \n There is no consolidation. Mild right basilar atelectasis persists. There is\n no pneumothorax. Moderate enlargement of the cardiomediastinal silhouette is\n stable.",
"image_path": [
"p18/p18224196/s55452685/4b21950a-5565f60b-5e86b9fd-fde33a71-2a564240.jpg"
],
"split": "test"
},
{
"id": "f144b596-88afdc30-0f893661-7b6e1b7c-29b129bf",
"study_id": 59718086,
"subject_id": 11569093,
"report": "As compared to the previous radiograph, there is no relevant\n change. Large fluid or pneumothorax on the right with air-fluid level in the\n posterior aspect of the lung. Massive generalized right-sided pleural\n thickening with slight decrease of the right hemithorax. Fibrotic changes of\n the lung parenchyma.\n \n On the left, there is no abnormality of the pleura or lung parenchyma. The\n left aspect of the heart border is unremarkable.",
"image_path": [
"p11/p11569093/s59718086/f144b596-88afdc30-0f893661-7b6e1b7c-29b129bf.jpg"
],
"split": "test"
},
{
"id": "96f6b655-cb517472-567ebf62-3c6395e0-01936fb3",
"study_id": 51943964,
"subject_id": 11413236,
"report": "impression: No evidence of pneumonia or pulmonary edema. Findings: Right chest wall Port-A-Cath terminates in the upper SVC. Postoperative\n mediastinum, including calcified left suprahilar lymph node, and cardiomegaly\n are unchanged from ___. Bibasilar atelectasis is mild.",
"image_path": [
"p11/p11413236/s51943964/96f6b655-cb517472-567ebf62-3c6395e0-01936fb3.jpg"
],
"split": "test"
},
{
"id": "829c6f86-9cb29e7d-e8f6a250-91dc2e24-bf216a9e",
"study_id": 58836461,
"subject_id": 15192710,
"report": "impression: Small left pleural effusion and improving atelectasis, but no\n pneumothorax. Findings: The cardiomediastinal and hilar contours are normal. Subtle linear\n horizontally oriented opacities in the left costophrenic angle appear improved\n compared to prior exams and likely reflect the sequelae of resolving\n atelectasis. There is no pneumothorax. A small left pleural effusion is\n seen.",
"image_path": [
"p15/p15192710/s58836461/829c6f86-9cb29e7d-e8f6a250-91dc2e24-bf216a9e.jpg"
],
"split": "test"
},
{
"id": "1c038d27-c6193e6a-d4588595-a78608bd-565e11fa",
"study_id": 51863042,
"subject_id": 19061282,
"report": "impression: 1. Interval progression of bilateral, right worse than left parenchymal\n opacities again concerning for multifocal infection and/or metastases.\n \n 2. Similar appearance of the mediastinum.\n \n 3. Probable small right pleural effusion, new from the prior exam.\n \n 4. Position of vascular stents with kinking of the right\n brachiocephalic/axillary vein stent is similar to the prior chest CT. Findings: The patient is rotated with his neck turned to the right. The tip of the\n tracheostomy tube appears appropriately positioned and unchanged. The\n configuration of the right subclavian vein and brachiocephalic vein stent\n appears similar to the prior chest CT with kinking of the stent at the level\n of the clavicle. The configuration of the left brachiocephalic vein stent is\n also similar to the prior CT. Bilateral right worse than left parenchymal\n opacities have progressed from the prior radiograph as well as CT, again\n concerning for multifocal infection and/or metastases. A right pleural\n effusion may be trace. The left pleural effusion may have resolved in the\n interim. No pneumothorax.\n \n The heart is normal in size. Mild prominence of the right mediastinum may\n correspond to the known mild ascending thoracic aortic aneurysm on prior CT. \n The size of the mediastinum is similar to the prior exam. Calcified right\n mediastinal lymph node is unchanged.\n \n Catheter projecting over the lower portion of the SVC is unchanged. Coils\n projecting over the left upper abdomen are also unchanged. Coarse\n calcifications projecting over the left upper abdomen are unchanged from the\n prior radiograph in correspond to splenic calcifications on the prior CT. \n Coarse calcifications in the soft tissue of the neck are unchanged from prior\n CT neck.",
"image_path": [
"p19/p19061282/s51863042/1c038d27-c6193e6a-d4588595-a78608bd-565e11fa.jpg"
],
"split": "test"
},
{
"id": "68d1a72f-0552bded-deae306a-343f5d03-ccf9853f",
"study_id": 55255832,
"subject_id": 11893091,
"report": "impression: Unchanged lead positions from recently inserted dual-chamber pacemaker. Findings: The lead positions of the dual-chamber pacemaker is unchanged\n compared to the prior exam. There is moderate cardiomegaly. The lungs\n demonstrate moderate pulmonary edema but no evidence of pleural effusions or\n pneumothorax. Mild atelectatic changes at the lung bases are unchanged.\n Incidental note is made of chronic stable calcified scarring in the left apex.\n There are no new parenchymal opacities. There is no evidence of pneumothorax.",
"image_path": [
"p11/p11893091/s55255832/68d1a72f-0552bded-deae306a-343f5d03-ccf9853f.jpg"
],
"split": "test"
},
{
"id": "d9e22f16-a5b260d1-2a5aee7a-4cd66d44-b590afb8",
"study_id": 53905237,
"subject_id": 19907884,
"report": "impression: Right IJ central venous catheter terminates projecting over the right atrium. \n No pneumothorax. Findings: Since most recent chest radiograph, there has been interval placement of a\n right IJ central venous catheter which terminates projecting over the right\n atrium. There is no pneumothorax. Lungs are clear. Persistent elevation the\n right hemidiaphragm is noted. Radiopaque lucencies overlie the right upper\n mediastinum.",
"image_path": [
"p19/p19907884/s53905237/d9e22f16-a5b260d1-2a5aee7a-4cd66d44-b590afb8.jpg"
],
"split": "test"
},
{
"id": "b128a59a-4eb90799-c8564692-8e582714-82706ad2",
"study_id": 56676503,
"subject_id": 15857729,
"report": "impression: NG tube ends in distal stomach. Remaining lines and tubes in satisfactory\n position.\n \n Right lower lobe pneumonia with stable severe bilateral airspace opacities,\n which may be due to pulmonary edema or hemorrhage.\n \n Moderate layering right pleural effusion not appreciably changed. Findings: A newly placed nasogastric tube terminates in the distal stomach. The right IJ\n central venous catheter and an ET tube are unchanged in position. The\n bilateral lung apices have been excluded from the field of view, limiting\n assessment for pneumothorax. Severe bilateral airspace opacities are\n unchanged. A small layering right pleural effusion is not appreciably changed.",
"image_path": [
"p15/p15857729/s56676503/b128a59a-4eb90799-c8564692-8e582714-82706ad2.jpg"
],
"split": "test"
},
{
"id": "eab11c59-32a5b9b8-b8d335fa-ce06c5fa-5bde0499",
"study_id": 53492798,
"subject_id": 10046166,
"report": "impression: No acute cardiopulmonary process. Findings: Frontal and lateral radiographs of the chest redemonstrate a round\n calcified pulmonary nodule in the posterior right lung base, unchanged from\n multiple priors and consistent with prior granulomatous disease. A known\n enlarged right hilar lymph node seen on CT of ___ likely accounts for the\n increased opacity at the right hilum. A known right mediastinal lymph node\n conglomerate accounts for the fullness at the right paratracheal region. No\n pleural effusion, pneumothorax or focal consolidation is present. The patient\n is status post median sternotomy and CABG with wires intact. The cardiac\n silhouette is normal in size. The mediastinal and hilar contours are\n unchanged from the preceding radiograph.",
"image_path": [
"p10/p10046166/s53492798/eab11c59-32a5b9b8-b8d335fa-ce06c5fa-5bde0499.jpg"
],
"split": "test"
},
{
"id": "155e0867-6925a927-7f73fa2f-6e5438bb-dc6ae8fc",
"study_id": 52374902,
"subject_id": 19182863,
"report": "impression: Left minimal apical pneumothorax is unchanged or slightly improved. The rest\n of the exam is stable. Findings: Tiny left apical pneumothorax is stable or slightly improved. The rest of the\n exam is unchanged with mild pulmonary edema and left middle lung opacity\n related to recent BAL. Prior sternotomy was done for aortic, mitral and\n tricuspid valve repair. Moderate cardiomegaly is stable.",
"image_path": [
"p19/p19182863/s52374902/155e0867-6925a927-7f73fa2f-6e5438bb-dc6ae8fc.jpg"
],
"split": "test"
},
{
"id": "bd3dc01c-c67b8f05-580c3880-de7352aa-4118828e",
"study_id": 50065267,
"subject_id": 17163861,
"report": "impression: Improving left basilar atelectasis. Findings: The patient is status post sternotomy. A dual-lead pacemaker/ICD\n device appears unchanged with leads again terminating in the right atrium and\n ventricle, respectively. There is patchy left basilar opacity, also obscuring\n the left lateral costophrenic sulcus, but somewhat decreased. Elsewhere, the\n lungs remain clear. There are no pleural effusions or pneumothorax. Small\n osteophytes are present throughout the visualized thoracic spine.",
"image_path": [
"p17/p17163861/s50065267/bd3dc01c-c67b8f05-580c3880-de7352aa-4118828e.jpg"
],
"split": "test"
},
{
"id": "a40681cf-5ae02ca8-00157e4a-2a48e28a-831224eb",
"study_id": 51215308,
"subject_id": 19757720,
"report": "As compared to the previous radiograph, there is a new parenchymal\n opacity at the right lung base. The opacity is strongly suggestive of\n pneumonia, given that the asymmetric location, the alveolar pattern, and the\n evidence of air bronchograms.\n \n The referring physician, ___. ___ was paged for notification at the time of\n dictation, 1:38 p.m., ___.\n \n Unchanged moderate cardiomegaly with minimal fluid overload. Unchanged\n presence of bilateral small pleural effusions restricted to the costophrenic\n sinuses, better visible on the lateral than on the frontal radiograph.\n \n Minimal left basal atelectasis.",
"image_path": [
"p19/p19757720/s51215308/a40681cf-5ae02ca8-00157e4a-2a48e28a-831224eb.jpg"
],
"split": "test"
},
{
"id": "5e0d77ce-231b152c-108568f2-d7021ce2-2afe69fa",
"study_id": 54545268,
"subject_id": 14851532,
"report": "impression: Slightly increased opacity at the left lower lung adjacent to the left heart\n border, with decrease in right basilar opacity compared with prior. Slight\n decrease in small right pleural effusion. Findings: Compared with prior radiographs on ___, there is slight increase in\n opacity in the left lower lung adjacent to the left heart border, with\n improved right basilar opacity. There is a small right pleural effusion,\n slightly decreased from prior. No pneumothorax. There is no overt pulmonary\n edema. The cardiac and mediastinal silhouettes are unchanged.",
"image_path": [
"p14/p14851532/s54545268/5e0d77ce-231b152c-108568f2-d7021ce2-2afe69fa.jpg"
],
"split": "test"
},
{
"id": "a7f13ec9-849ac14d-c01cebdb-4ec75cc0-3f0f2ca6",
"study_id": 56440919,
"subject_id": 15659181,
"report": "impression: No acute cardiopulmonary process. Findings: The lungs are clear without focal consolidation. No pleural effusion or\n pneumothorax is seen. The cardiac and mediastinal silhouettes are\n unremarkable.",
"image_path": [
"p15/p15659181/s56440919/a7f13ec9-849ac14d-c01cebdb-4ec75cc0-3f0f2ca6.jpg"
],
"split": "test"
},
{
"id": "1bc3bed7-2aa120b0-65805fec-266c7e92-f3eebc0a",
"study_id": 54103570,
"subject_id": 14841168,
"report": "impression: Endotracheal tube 4.1 cm of the carina. Enteric tube should be advanced 5-6\n cm for ideal positioning. No pneumothorax. The left lung base is only\n partially imaged however opacity at the base of the left lung likely reflects\n atelectasis or aspiration. Mild pulmonary edema. Findings: An endotracheal tube terminates 4.1 cm above the carina. In enteric tube\n terminates in the proximal stomach and could be advanced 5-6 cm for ideal\n positioning.\n \n The cardiomediastinal silhouette is stable. Low lung volumes. Minimal\n elevation of the right hemidiaphragm is also stable. The left lung base is\n not visualized. Increased opacity at the base of the left lung may reflect\n atelectasis. There is mild vascular congestion with mild pulmonary edema. No\n pneumothorax.",
"image_path": [
"p14/p14841168/s54103570/1bc3bed7-2aa120b0-65805fec-266c7e92-f3eebc0a.jpg"
],
"split": "test"
},
{
"id": "78a4e7a2-9072e849-a90eb438-518cd14b-3ea197d4",
"study_id": 53458437,
"subject_id": 14295224,
"report": "impression: Right upper lobe infiltrate has improved since ___. There is no\n new lung consolidation. Findings: The patient has prior history of gastric pull-through with radiation therapy\n for esophageal cancer.\n \n Right upper lobe consolidation in posterior segment has slightly improved. \n The lungs are hyperinflated. 6 mm right lower lobe nodule is unchanged since\n ___. Small right pleural effusion is stable since ___. There is\n no pneumothorax. Mediastinal and cardiac contours are normal.",
"image_path": [
"p14/p14295224/s53458437/78a4e7a2-9072e849-a90eb438-518cd14b-3ea197d4.jpg"
],
"split": "test"
},
{
"id": "8452bd2c-ba775d23-e46872fa-f0e9c5bd-63897743",
"study_id": 50636786,
"subject_id": 10933609,
"report": "impression: 1. Standard positions of the endotracheal and orogastric tubes.\n \n 2. Focal, somewhat linear opacities within both upper lobes which may be due\n to a chronic interstitial process. Correlation with prior imaging is\n recommended. Aspiration or infection, however, cannot be completely excluded.\n \n 3. Mild pulmonary vascular congestion in the setting of low lung volumes. Findings: Endotracheal tube tip terminates approximately 3.8 cm from the carina. An\n orogastric tube tip is noted within the distal stomach. Lung volumes are low.\n Heart size is normal. Mediastinal contours are unremarkable. Crowding of the\n bronchovascular structures is noted, and mild pulmonary vascular congestion is\n likely present. Additionally, more focal somewhat linear opacities within\n both upper lobes appear to be associated with fibrotic changes. No pleural\n effusion or pneumothorax is identified, although the right costophrenic angle\n is excluded from the field of view. Diffuse gaseous distention of the bowel\n loops are noted within the upper abdomen. No acute osseous abnormality seen. \n Surgical anchors are noted projecting over the right shoulder.",
"image_path": [
"p10/p10933609/s50636786/8452bd2c-ba775d23-e46872fa-f0e9c5bd-63897743.jpg"
],
"split": "test"
},
{
"id": "66fece2b-2fccf418-d23f1eda-9dde45e2-d85df8da",
"study_id": 56541072,
"subject_id": 17337033,
"report": "impression: No acute cardiopulmonary abnormality. Findings: Heart size is normal. The aorta is tortuous. Unchanged widening of the\n mediastinum attributable to mediastinal lipomatosis is re- demonstrated. \n Hilar contours are unremarkable. Pulmonary vasculature is not engorged. \n Lungs are clear. No pleural effusion, focal consolidation or pneumothorax is\n demonstrated. There are no acute osseous abnormalities.",
"image_path": [
"p17/p17337033/s56541072/66fece2b-2fccf418-d23f1eda-9dde45e2-d85df8da.jpg"
],
"split": "test"
},
{
"id": "2cdf54d6-df90d07a-cbaaa135-454278cd-ffe7eb4e",
"study_id": 52673752,
"subject_id": 15809646,
"report": "impression: Interval improvement of opacities along the right lower lung with\n bibasilar atelectasis. Findings: As compared to prior chest radiograph from ___, there\n has been interval improvement of opacities along the right lower lung. There\n is bibasilar atelectasis. Mild cardiomegaly is unchanged. There are no\n pleural effusions or pneumothorax. An ET tube ends 3.9 cm above the carina. \n Right jugular line is unchanged in position.",
"image_path": [
"p15/p15809646/s52673752/2cdf54d6-df90d07a-cbaaa135-454278cd-ffe7eb4e.jpg"
],
"split": "test"
},
{
"id": "53c61f6b-13463b44-509c8ec2-1dc260ad-9136011d",
"study_id": 51895071,
"subject_id": 14851532,
"report": "impression: No acute cardiac or pulmonary findings. Findings: Frontal and lateral radiographs of the chest were acquired. \n Scattered parenchymal opacities within both lungs are not significantly\n changed compared to the most recent chest radiograph from ___,\n correlating to areas of post-treatment change and known neoplastic disease. \n There is no focal consolidation. The heart size is normal. The mediastinal\n contours are normal. There are no definite pleural effusions. No\n pneumothorax is seen. Left-sided rib deformities are redemonstrated. Suture\n chain is seen within the left upper lung, as before.",
"image_path": [
"p14/p14851532/s51895071/53c61f6b-13463b44-509c8ec2-1dc260ad-9136011d.jpg"
],
"split": "test"
},
{
"id": "de739d0b-2345495b-255f0e3b-00ccbf4c-ab4d3400",
"study_id": 52138943,
"subject_id": 13263843,
"report": "AP single view of the chest has been obtained in this patient with\n semi-upright position. Analysis is performed in direct comparison with the\n next preceding portable chest examination of ___.\n \n Status post right upper lobectomy unchanged. Cardiac enlargement as before\n may have even increased slightly. On previous examination identified small\n caliber pigtail end catheter in the right lateral pleural sinus is still\n present. The amount of pleural fluid density has increased mildly. No\n pneumothorax has developed. Overall increased hazy appearance of the lung\n bases coinciding with perivascular haze in the pulmonary vessels is suggestive\n of increased CHF in this patient. No new discrete local parenchymal\n infiltrates suggestive of pneumonia are identified.",
"image_path": [
"p13/p13263843/s52138943/de739d0b-2345495b-255f0e3b-00ccbf4c-ab4d3400.jpg"
],
"split": "test"
},
{
"id": "7d45bb0a-531ab42d-d3820493-112d47e5-6eafa5a1",
"study_id": 51719671,
"subject_id": 19016834,
"report": "impression: There is continued opacification of the right lung base, possibly\n reflecting a combination of pleural effusion with atelectasis, though\n infection cannot be excluded. Small right pleural effusion is unchanged. Findings: Patient is status post esophagectomy\n and gastric pull-through procedure with a stent redemonstrated within the\n neoesophagus. Cardiac silhouette size is normal. The mediastinal contour is\n similar. There is persistent opacification of the right lung base with a\n small right pleural effusion, not significantly changed in size. Left lung is\n clear. There is no pneumothorax. No pulmonary vascular congestion is\n present.",
"image_path": [
"p19/p19016834/s51719671/7d45bb0a-531ab42d-d3820493-112d47e5-6eafa5a1.jpg"
],
"split": "test"
},
{
"id": "053ef377-da66ede4-ca590556-c5ee239e-a4d98f53",
"study_id": 58103596,
"subject_id": 18338007,
"report": "impression: New central vascular congestion with mild interstitial edema. Findings: Again seen is marked elevation of the left\n hemidiaphragm, with adjacent compressive atelectasis. Gas is seen within the\n splenic flexure. There is mild central pulmonary vascular congestion with\n mild interstitial edema, new since ___. There is no\n pneumothorax or pleural effusion. The heart size is normal.",
"image_path": [
"p18/p18338007/s58103596/053ef377-da66ede4-ca590556-c5ee239e-a4d98f53.jpg"
],
"split": "test"
},
{
"id": "2590bcf5-32f61859-59ee1db2-197c844f-fa816534",
"study_id": 53138800,
"subject_id": 14353044,
"report": "As compared to the previous radiograph, there is no relevant\n change. Status post spinal stabilization, left subclavian access line. \n Borderline size of the cardiac silhouette, elevation of the right\n hemidiaphragm with subsequent areas of atelectasis seen on both the frontal\n and the lateral radiograph. No newly appeared parenchymal opacities. No\n larger pleural effusions.",
"image_path": [
"p14/p14353044/s53138800/2590bcf5-32f61859-59ee1db2-197c844f-fa816534.jpg"
],
"split": "test"
},
{
"id": "4d69cce1-fecc3019-ee62f6c0-dc12a81e-ae02844a",
"study_id": 53482917,
"subject_id": 14081759,
"report": "No previous images. There is hyperexpansion of the lungs\n suggestive of chronic pulmonary disease. Prominence of engorged and\n ill-defined pulmonary vessels is consistent with the clinical diagnosis of\n pulmonary vascular congestion, though in the absence of previous images it is\n difficult to determine whether any this appearance could reflect underlying\n chronic pulmonary disease. The possibility of supervening consolidation would\n be impossible to exclude on this single study, especially without a lateral\n view.\n \n No evidence of pneumothorax.",
"image_path": [
"p14/p14081759/s53482917/4d69cce1-fecc3019-ee62f6c0-dc12a81e-ae02844a.jpg"
],
"split": "test"
},
{
"id": "67a20282-74cc43b9-69dd3914-1cb897d2-cb2f6018",
"study_id": 50598243,
"subject_id": 16508811,
"report": "As compared to the previous radiograph, the pre-existing opacity in\n the right lung apex has completely resolved. However, opacities at both lung\n bases are still present. The opacities appear less dense than on the previous\n image. Currently, no evidence of pulmonary edema is present. The size of the\n cardiac silhouette is at the upper range of normal. There is no evidence of\n pleural effusions on the frontal and lateral images.",
"image_path": [
"p16/p16508811/s50598243/67a20282-74cc43b9-69dd3914-1cb897d2-cb2f6018.jpg"
],
"split": "test"
},
{
"id": "480f169c-15ef13a4-4ca3b85d-181a240e-edc79169",
"study_id": 57780214,
"subject_id": 19404187,
"report": "impression: Improving left upper lung zone consolidation compared to ___. Findings: There is still an area of increased density in the left upper lobe\n projecting over the anterior aspect of the second rib measuring approximately\n 2.9 x 2.2 cm, improved from ___. The cardiomediastinal\n silhouette is normal. There is no pleural effusion or pneumothorax.",
"image_path": [
"p19/p19404187/s57780214/480f169c-15ef13a4-4ca3b85d-181a240e-edc79169.jpg"
],
"split": "test"
},
{
"id": "81da6609-5b1db1a9-985ed5af-0ea8bff9-d2ae3e08",
"study_id": 59608718,
"subject_id": 18309149,
"report": "impression: Stable small right pleural effusion compared to ___. \n This study neither suggests nor excludes the diagnosis of pulmonary embolism. Findings: PA and lateral chest radiographs demonstrate no interval change\n from ___. Small right pleural effusion, adjacent atelectasis, and scar\n formation are stable. The cardiomediastinal silhouette is normal. The left\n hemithorax is unremarkable.",
"image_path": [
"p18/p18309149/s59608718/81da6609-5b1db1a9-985ed5af-0ea8bff9-d2ae3e08.jpg"
],
"split": "test"
},
{
"id": "d43e3c28-8d1a4b0c-ef446460-413e4e0b-df3a80ef",
"study_id": 53734902,
"subject_id": 17327592,
"report": "In comparison with the study of ___, there is again substantial\n elevation of the right hemidiaphragmatic contour. Opacification above this\n could reflect atelectasis, though in the appropriate clinical setting\n supervening pneumonia would have to be considered.\n \n Some prominence of the cardiac silhouette persists in a patient with intact\n midline sternal wires. No evidence of vascular congestion and the left lung\n is essentially clear.",
"image_path": [
"p17/p17327592/s53734902/d43e3c28-8d1a4b0c-ef446460-413e4e0b-df3a80ef.jpg"
],
"split": "test"
},
{
"id": "99d55522-c421c3a3-4e043495-a4e139ff-69c8f48f",
"study_id": 52578881,
"subject_id": 16360107,
"report": "PA and lateral chest views have been obtained with patient in\n upright position. There is evidence of sternotomy and previous bypass surgery\n with moderate cardiac enlargement. The pulmonary vasculature demonstrates an\n upper zone redistribution pattern, but no conclusive evidence for interstitial\n or alveolar edema is present. Bilateral pleural space thickenings are seen\n along the lateral lower chest walls measuring up to 3 and 4 cm at the bases. \n The pleural densities extend into the posterior compartments as identified on\n the lateral view. There is no evidence of new acute pulmonary parenchymal\n infiltrates. No evidence of pneumothorax exists in the apical area. When\n comparison is made with the next preceding portable chest examination of\n ___, the described mostly basal located pleural thickenings were\n similar and appear rather stable. The pulmonary vasculature appears, however,\n now slightly more congested. Review of previous PA and lateral chest\n examinations from ___, ___ and ___ demonstrated that the pleural\n thickenings existed already at that time. Considering the rather stable\n pleural thickenings could consider that they are at least in part organized\n and represent scar formations in this patient with history of end-stage renal\n disease.",
"image_path": [
"p16/p16360107/s52578881/99d55522-c421c3a3-4e043495-a4e139ff-69c8f48f.jpg"
],
"split": "test"
},
{
"id": "154a0276-f9cc72dc-9907f2e1-f1f11272-93cc90ff",
"study_id": 56921446,
"subject_id": 11413236,
"report": "impression: Low lung volumes but no acute process and no evidence of free\n peritoneal air. Findings: PA and lateral chest radiographs were provided. Lung volumes are\n significantly low. There is no focal consolidation, pleural effusion or\n pneumothorax. There is bibasilar atelectasis. The cardiomediastinal\n silhouette is unchanged. Median sternotomy wires are intact. A right chest\n wall Port-A-Cath terminates at the cavoatrial junction. There is no free air\n under the hemidiaphragms. Osseous structures are intact.",
"image_path": [
"p11/p11413236/s56921446/154a0276-f9cc72dc-9907f2e1-f1f11272-93cc90ff.jpg"
],
"split": "test"
},
{
"id": "db46fb79-5ef144b5-a30257dc-a364a08f-731905ea",
"study_id": 59299448,
"subject_id": 14841168,
"report": "impression: Continued mild pulmonary vascular congestion with a small right\n pleural effusion. Left basilar atelectasis. Findings: The right PICC has been removed in the\n interval. There is moderate enlargement of the cardiac silhouette which is not\n significantly changed from the prior exam. The mediastinal and hilar contours\n are unchanged, with continued widening of the mediastinum and aortic knob\n calcifications redemonstrated. Mild pulmonary vascular congestion persists,\n and is not significantly changed in the interval. Left basilar atelectasis is\n also noted, with a small right pleural effusion. No pneumothorax is\n identified.",
"image_path": [
"p14/p14841168/s59299448/db46fb79-5ef144b5-a30257dc-a364a08f-731905ea.jpg"
],
"split": "test"
},
{
"id": "ff4c00a4-74c0b483-307446fe-e534b390-224db689",
"study_id": 52680917,
"subject_id": 19075045,
"report": "impression: Reduced left upper lobe opacification likely for reduced edema\n component. Reduced left base pleural effusion, but increase in the right\n base. Findings: All the monitoring and support devices are unchanged within\n standard position. Patient is after sternotomy for cardiac surgery. Lung\n volume is still low but the left upper lobe opacification is reduced, likely\n for reabsorption of edema component. Also, the left base pleural effusion is\n reduced. The right basilar opacification is slightly increased for increased\n pleural effusion. Heart is still mildly enlarged. There is no pneumothorax.",
"image_path": [
"p19/p19075045/s52680917/ff4c00a4-74c0b483-307446fe-e534b390-224db689.jpg"
],
"split": "test"
},
{
"id": "c689d99c-d2fa5c84-6112de6e-adc7466b-c0209f29",
"study_id": 53776243,
"subject_id": 13448574,
"report": "impression: No evidence of acute disease. No convincing evidence for\n sarcoidosis. Findings: The heart is normal in size. The mediastinal and hilar contours\n appear within normal limits and do not suggest substantial lymph node\n enlargement. There is no pleural effusion or pneumothorax. The lungs appear\n clear. Mild degenerative changes are similar along the thoracic spine.",
"image_path": [
"p13/p13448574/s53776243/c689d99c-d2fa5c84-6112de6e-adc7466b-c0209f29.jpg"
],
"split": "test"
},
{
"id": "57acf73e-ba3f0114-8d77513c-7aee7bf4-4afa327e",
"study_id": 58387591,
"subject_id": 15144601,
"report": "impression: No radiographic evidence for acute cardiopulmonary process. Findings: Transvenous pacemaker/AICD with leads seen terminating in right atrium and\n right ventricle. The lungs are clear without evidence of consolidation,\n pleural effusion, pneumothorax, or overt pulmonary edema. Stable, mild to\n moderate cardiomegaly is noted. The aorta is somewhat tortuous, but stable.\n Median sternotomy wires appear aligned and intact.",
"image_path": [
"p15/p15144601/s58387591/57acf73e-ba3f0114-8d77513c-7aee7bf4-4afa327e.jpg"
],
"split": "test"
},
{
"id": "f0de6eac-d8d4cc43-59d26e49-46200472-34fa5de1",
"study_id": 51909516,
"subject_id": 18338007,
"report": "Lung volumes remain low, accentuating the cardiac silhouette and\n bronchovascular structures. With this limitation in mind, cardiomediastinal\n contours are stable in appearance. Persistent elevation of left hemidiaphragm\n with adjacent atelectasis at the left lower lobe. Right retrocardiac\n atelectasis is also similar to the prior study.",
"image_path": [
"p18/p18338007/s51909516/f0de6eac-d8d4cc43-59d26e49-46200472-34fa5de1.jpg"
],
"split": "test"
},
{
"id": "8de15662-1ddba4f0-7784313d-51c003d0-f3d4cc1b",
"study_id": 55058862,
"subject_id": 13263843,
"report": "impression: Mild pulmonary vascular congestion with moderate to large right pleural\n effusion and small left pleural effusions. Right basilar opacification may\n reflect atelectasis and/or infection. Findings: The cardiac silhouette size remains mildly enlarged. Patient is status post\n right upper lobectomy and right upper chest wall resection with evidence of\n volume loss in the right lung and posttreatment changes in the right upper\n lung field, unchanged. Left hilar enlargement is unchanged, with mild\n pulmonary vascular congestion present. Moderate to large right pleural\n effusion and small left pleural effusion are again demonstrated, not\n significantly changed in the interval. Right basilar opacification is similar.\n No pneumothorax is identified. The aorta remains tortuous and calcified.",
"image_path": [
"p13/p13263843/s55058862/8de15662-1ddba4f0-7784313d-51c003d0-f3d4cc1b.jpg"
],
"split": "test"
},
{
"id": "6f09dfe3-4459d697-aed9e9be-f9f1b26e-d80bcd0e",
"study_id": 53430284,
"subject_id": 11293517,
"report": "In comparison with study of ___, there is again enlargement of the\n cardiac silhouette with a pacer device in place. No definite vascular\n congestion, raising the possibility of underlying cardiomyopathy or\n pericardial effusion. No acute focal pneumonia.\n \n The right PICC line has been removed.",
"image_path": [
"p11/p11293517/s53430284/6f09dfe3-4459d697-aed9e9be-f9f1b26e-d80bcd0e.jpg"
],
"split": "test"
},
{
"id": "2d3d526f-5560ef5c-de1b0d4a-b17b0f0b-427cc0ca",
"study_id": 55339618,
"subject_id": 13475033,
"report": "impression: 1. No acute intrathoracic process. Stable bilateral interstitial markings,\n likely chronic lung disease.\n 2. Coronary artery calcifications. Findings: There are diffuse bilateral interstitial markings, overall unchanged since\n ___. This is consistent with chronic lung disease. No new areas of\n focal consolidation or pleural effusions. No pneumothorax. Heart size is top\n normal, stable from prior. Atherosclerotic calcifications are seen in the\n coronary arteries, better appreciated on the lateral view.",
"image_path": [
"p13/p13475033/s55339618/2d3d526f-5560ef5c-de1b0d4a-b17b0f0b-427cc0ca.jpg"
],
"split": "test"
},
{
"id": "430e6100-bae3aa34-d72132a7-2c61b505-8d2056bb",
"study_id": 59842151,
"subject_id": 16508811,
"report": "impression: Mild interval worsening of pulmonary edema with unchanged left pleural\n effusion and cardiomegaly. Findings: Lines and Tubes: Stable right IJ line tip position.\n Lungs: Low lung volumes with mild worsening of pulmonary edema.\n \n Pleura: Small left pleural effusion.\n \n Mediastinum: Stable cardiomegaly.\n \n Bony thorax: No change",
"image_path": [
"p16/p16508811/s59842151/430e6100-bae3aa34-d72132a7-2c61b505-8d2056bb.jpg"
],
"split": "test"
},
{
"id": "3352c0d5-7f41c92d-b1178750-7dc794c6-979ffba3",
"study_id": 57619468,
"subject_id": 16015751,
"report": "impression: Vague nodular opacity projecting over the right mid lung, likely\n a nipple shadow, but confirmation with a repeat PA view with nipple markers is\n recommended when clinically appropriate. No evidence of acute disease. Findings: The heart is normal in size. The mediastinal and hilar contours\n are unremarkable. There is no pleural effusion or pneumothorax. There is a\n vague nodular focus projecting over the right lateral lung measuring about 8\n mm in diameter. Otherwise the lungs appear clear.",
"image_path": [
"p16/p16015751/s57619468/3352c0d5-7f41c92d-b1178750-7dc794c6-979ffba3.jpg"
],
"split": "test"
},
{
"id": "3fb53bea-f1dad119-d26160af-4b106702-04691d32",
"study_id": 53896301,
"subject_id": 14744884,
"report": "impression: Low lung volumes which limits assessment of the lung bases. Patchy opacities\n at the lung bases likely reflect atelectasis. Mild pulmonary vascular\n congestion. Findings: Lung volumes are low. The heart is top-normal size given the lung volumes. \n There is crowding of the bronchovascular structures with probable mild\n pulmonary vascular congestion. Patchy opacities in lung bases may reflect\n atelectasis. There are no large pleural effusions or pneumothorax. Right\n brachiocephalic/subclavian stent is again demonstrated.",
"image_path": [
"p14/p14744884/s53896301/3fb53bea-f1dad119-d26160af-4b106702-04691d32.jpg"
],
"split": "test"
},
{
"id": "f39a0cd8-fb45cb6e-63f5fa30-21668913-0ac228d3",
"study_id": 57882993,
"subject_id": 13450581,
"report": "A spiculated and cavitary nodule in the left mid lung at the level\n of the third left anterior rib measuring 2.5 cm in diameter appears slightly\n larger than on the prior radiograph and corresponds to a known left upper lobe\n lesion on prior CT of ___. It is morphologically concerning for\n a primary lung cancer and less likely an indolent granulomatous infection. \n Lungs are otherwise clear, with no new focal areas of consolidation to suggest\n the presence of an acute pneumonia. Lungs are otherwise remarkable for linear\n scar versus atelectasis in the mid lung regions. Sclerosis of medial left\n clavicle, likely due to prior trauma, is unchanged.",
"image_path": [
"p13/p13450581/s57882993/f39a0cd8-fb45cb6e-63f5fa30-21668913-0ac228d3.jpg"
],
"split": "test"
},
{
"id": "17ff7369-20912497-3b539b61-9c4ace20-7dc7fa12",
"study_id": 51244261,
"subject_id": 12702423,
"report": "impression: Increasing opacity in the left lower lung, concerning for\n worsening consolidation and effusion. Extensive metastatic disease within the\n chest. Refer to subsequent CT for further details. Findings: Portable AP upright chest radiograph was obtained. Compared to the\n scout radiograph from a torso CT from ___, there is increased opacity in\n the left lower lung, concerning for worsening effusion and consolidation. \n Extensive nodularity in the lungs is compatible with known metastatic disease.\n Heart size cannot be assessed. Bony structures appear unchanged.",
"image_path": [
"p12/p12702423/s51244261/17ff7369-20912497-3b539b61-9c4ace20-7dc7fa12.jpg"
],
"split": "test"
},
{
"id": "2b68ac0e-611f3a5f-ddd4047f-97ef55a1-538b75df",
"study_id": 55785509,
"subject_id": 10268877,
"report": "In comparison with study of ___, the PICC extends only to the left\n brachiocephalic vein before its junction with the superior vena cava. \n Continued low lung volumes may account for some of the prominence of the\n transverse diameter of the heart. Bibasilar opacification most likely\n reflects atelectatic changes. Possibility of supervening pneumonia would have\n to be considered in the appropriate clinical setting.\n \n The pulmonary vascular congestion is less prominent than on the prior study.",
"image_path": [
"p10/p10268877/s55785509/2b68ac0e-611f3a5f-ddd4047f-97ef55a1-538b75df.jpg"
],
"split": "test"
},
{
"id": "9cf8e1b3-4a4ea8dd-33fc8814-862d81e5-34c105d1",
"study_id": 58040849,
"subject_id": 17340686,
"report": "As compared to the previous radiograph, there is no relevant\n change. Low lung volumes. Moderate cardiomegaly with minimal fluid overload.\n No overt pulmonary edema. No pleural effusions. No pneumonia.",
"image_path": [
"p17/p17340686/s58040849/9cf8e1b3-4a4ea8dd-33fc8814-862d81e5-34c105d1.jpg"
],
"split": "test"
},
{
"id": "7e35b00e-b26953b2-8748806e-5162f99f-feffc6b2",
"study_id": 56374996,
"subject_id": 18079481,
"report": "In comparison with the earlier study of this date, the patient has\n taken a somewhat better inspiration. Nevertheless, lines are still low. \n There is enlargement of the cardiac silhouette with vascular congestion and\n bilateral effusions with compressive atelectasis. Nasogastric tube extends to\n the distal stomach.",
"image_path": [
"p18/p18079481/s56374996/7e35b00e-b26953b2-8748806e-5162f99f-feffc6b2.jpg"
],
"split": "test"
},
{
"id": "d570aba7-45a558d7-52f77673-704bdc98-85e97946",
"study_id": 53183707,
"subject_id": 10274145,
"report": "impression: No evidence of pneumonia. Stable cardiomegaly. Findings: The lungs are clear bilaterally with\n no areas of focal consolidation. There is no pleural effusion or\n pneumothorax. Patient is status post CABG. Cardiomegaly is stable. \n Mediastinal silhouette is within normal limits.",
"image_path": [
"p10/p10274145/s53183707/d570aba7-45a558d7-52f77673-704bdc98-85e97946.jpg"
],
"split": "test"
},
{
"id": "651f114e-84947603-ffc43734-98f192e7-c9c6afe0",
"study_id": 55999205,
"subject_id": 16360107,
"report": "impression: Mild pulmonary vascular congestion with unchanged\n small-to-moderate sized bilateral pleural effusions with laterally loculated\n components. Probable bibasilar atelectasis. Findings: Right-sided dual-lumen\n hemodialysis catheter is noted with tip terminating at the junction of the SVC\n and right atrium. The patient is status post median sternotomy and CABG, with\n multiple broken median sternotomy wires redemonstrated. Heart size is top\n normal. There are low lung volumes, with crowding of the bronchovascular\n structures and likely mild pulmonary vascular congestion. Bilateral pleural\n effusions are again noted, which appear loculated laterally and are similar in\n size when compared to the prior study. Patchy opacities at the lung bases\n most likely reflect atelectasis. No pneumothorax is identified. There are no\n acute osseous abnormalities. The mediastinal contour is unchanged with aortic\n knob calcifications again noted.",
"image_path": [
"p16/p16360107/s55999205/651f114e-84947603-ffc43734-98f192e7-c9c6afe0.jpg"
],
"split": "test"
},
{
"id": "93ad1f3b-e27d8070-8b21fc81-09c13461-bde10e1c",
"study_id": 56771404,
"subject_id": 15659181,
"report": "impression: 1. No focal consolidation.\n \n 2. Enlarged left hilum which could reflect hilar lymphadenopathy. CT is\n recommended for further evaluation. Findings: The lungs are well inflated and clear. The cardiac silhouette is normal. The\n left hilum appears enlarged. There is no pleural effusion or pneumothorax.",
"image_path": [
"p15/p15659181/s56771404/93ad1f3b-e27d8070-8b21fc81-09c13461-bde10e1c.jpg"
],
"split": "test"
},
{
"id": "51b6ffe9-580e1dd3-9aa94073-a614dd4f-e41809b0",
"study_id": 59995358,
"subject_id": 11569093,
"report": "The patient has been extubated. Parenchymal opacities in the left\n lung are similar to mildly worsened. A left internal jugular vein catheter\n terminates in the mid SVC. The NG tube is no longer present. Again seen is\n the large right subpulmonic effusion. The small left pleural effusion is\n unchanged. There is no pneumothorax.",
"image_path": [
"p11/p11569093/s59995358/51b6ffe9-580e1dd3-9aa94073-a614dd4f-e41809b0.jpg"
],
"split": "test"
},
{
"id": "5508a85f-2f9f244d-d22cda11-0527ab51-a15d5058",
"study_id": 53130454,
"subject_id": 15659181,
"report": "impression: No acute cardiopulmonary abnormality.\n Density in the retrosternal space suggests the presence of an anterior\n mediastinal lesion. CT is recommended for further evaluation Findings: The Cardiac size is normal. New density in the retrosternal clear space\n suggests the presence of an anterior mediastinal lesion, of note in prior CT\n there were enlarge lymph nodes in this location. The pulmonary vasculature is\n normal. The lungs are clear. There is no pleural effusion or pneumothorax. \n Basilar atelectasis is noted. Several wedge shaped compression fractures are\n long standing",
"image_path": [
"p15/p15659181/s53130454/5508a85f-2f9f244d-d22cda11-0527ab51-a15d5058.jpg"
],
"split": "test"
},
{
"id": "86d4ab20-e9abbc54-b65af50f-128d2b48-d9884715",
"study_id": 55001746,
"subject_id": 18512911,
"report": "impression: Bibasilar opacities, likely atelectases, and mild pulmonary\n vascular engorgement. If there is clinical concern for infection, recommend\n repeat dedicated AP and lateral views in the department. Findings: Portable upright chest radiograph demonstrates interval increase in\n bibasilar opacity, without large pleural effusion or pneumothorax. The\n cardiac silhouette remains mildly enlarged, the mediastinal contours are\n normal. The pulmonary vasculature is mildly engorged. There is no edema.",
"image_path": [
"p18/p18512911/s55001746/86d4ab20-e9abbc54-b65af50f-128d2b48-d9884715.jpg"
],
"split": "test"
},
{
"id": "12f2d9bf-89dc902e-a9cd6aaa-22c63b63-c5abd408",
"study_id": 57142346,
"subject_id": 14295224,
"report": "impression: 1. Resolution of pneumonia since ___ radiograph. No evidence of\n recurrence pneumonia Findings: The patient is status of previous radiation therapy in the right lung, with\n associated geographically marginated radiation fibrosis in the right\n paramediastinal and hilar regions with associated volume loss in the right\n lung. Pleural thickening at the right apex and right costophrenic angle also\n appear stable. Heterogeneous lung opacities in the right lung on the ___ radiograph have resolved. No new areas of consolidation are\n identified. A sub cm nodular opacity is seen in the periphery of the right\n lower lung and appears unchanged from ___ radiograph, corresponding to\n a subpleural nodule on CT of ___.",
"image_path": [
"p14/p14295224/s57142346/12f2d9bf-89dc902e-a9cd6aaa-22c63b63-c5abd408.jpg"
],
"split": "test"
},
{
"id": "7edb7bdc-93380e91-4d5d0b73-0c778fdb-40e32018",
"study_id": 57835182,
"subject_id": 16853729,
"report": "impression: No significant interval change since exam from two days prior\n demonstrating persistent bibasilar opacities and enlarged cardiomediastinal\n silhouette. Findings: PA and lateral views of the chest are compared to previous exam from\n ___. When compared to prior, there has been no significant\n interval change. Again seen are predominantly linear bibasilar opacities,\n more apparent on the lateral view on today's exam. Superiorly, the lungs\n remain clear. Enlarged cardiomediastinal silhouette is grossly stable given\n differences in technique and patient position.",
"image_path": [
"p16/p16853729/s57835182/7edb7bdc-93380e91-4d5d0b73-0c778fdb-40e32018.jpg"
],
"split": "test"
},
{
"id": "5c3a891f-05d81eb0-c4ade60a-d0b2c55e-b6856098",
"study_id": 56354797,
"subject_id": 12952223,
"report": "impression: Over last 24 hours, mild pulmonary edema has significantly\n improved, moderate right and small left pleural effusion as well as bilateral\n lower lung atelectasis are unchanged. Findings: Bilateral lung volumes are lower. Since yesterday,\n mild-to-moderately severe pulmonary edema has significantly improved. \n However, moderate right pleural effusion associated with right lower lung\n atelectasis and left lower lung atelectasis and small left pleural effusions\n are unchanged. The lung effusions and atelectasis obscuring the mediastinal\n border, thus assessment of the cardiomediastinum was limited.",
"image_path": [
"p12/p12952223/s56354797/5c3a891f-05d81eb0-c4ade60a-d0b2c55e-b6856098.jpg"
],
"split": "test"
},
{
"id": "cf6229c4-0dbb5dd3-64610954-17ed414a-c7d2837d",
"study_id": 51904170,
"subject_id": 17288844,
"report": "impression: Asymmetric mild right pulmonary edema has improved over last 24\n hours. Intraaortic balloon pump lies approximately 2.6 cm from the apex of\n aortic arch. Findings: Endotracheal tube ends approximately 4.8 cm above the carina and is\n appropriate in position. Intraaortic balloon pump lies approximately 2.6 cm\n from the apex of the aortic arch. The patient is status post median\n sternotomy with intact sternal sutures. Gastric tube courses below the\n diaphragm into the stomach; however, its distal end is beyond the field of\n view. Asymmetric, mild, right pulmonary edema has improved over last 24\n hours. Normal heart size. The mediastinal and hilar contours are unchanged. \n There is no pleural effusion.",
"image_path": [
"p17/p17288844/s51904170/cf6229c4-0dbb5dd3-64610954-17ed414a-c7d2837d.jpg"
],
"split": "test"
},
{
"id": "87ab8784-89bb34a7-0cd83f89-8208e8d6-8ceaaf76",
"study_id": 59249240,
"subject_id": 13849733,
"report": "In comparison with the study of ___, there appears to be further\n increase in the substantial right pleural effusion. There is evidence of\n compressive atelectasis at the base. Some opacification just above the level\n of the effusion on the frontal view could possibly be a manifestation of\n consolidation in the appropriate clinical setting.\n \n Remainder of this study is unchanged.",
"image_path": [
"p13/p13849733/s59249240/87ab8784-89bb34a7-0cd83f89-8208e8d6-8ceaaf76.jpg"
],
"split": "test"
},
{
"id": "6b022472-268f6ea1-33a11fa1-55b44ef6-3efa06ec",
"study_id": 53896301,
"subject_id": 14744884,
"report": "impression: Low lung volumes which limits assessment of the lung bases. Patchy opacities\n at the lung bases likely reflect atelectasis. Mild pulmonary vascular\n congestion. Findings: Lung volumes are low. The heart is top-normal size given the lung volumes. \n There is crowding of the bronchovascular structures with probable mild\n pulmonary vascular congestion. Patchy opacities in lung bases may reflect\n atelectasis. There are no large pleural effusions or pneumothorax. Right\n brachiocephalic/subclavian stent is again demonstrated.",
"image_path": [
"p14/p14744884/s53896301/6b022472-268f6ea1-33a11fa1-55b44ef6-3efa06ec.jpg"
],
"split": "test"
},
{
"id": "5337ec0a-283bf318-55060740-77ac2e55-67b5f668",
"study_id": 58958987,
"subject_id": 18929056,
"report": "impression: 1. Hyperinflated lungs suggest chronic obstructive pulmonary disease.\n 2. Slight increase in opacity at the right lung base may relate to\n atelectasis, although in the appropriate clinical setting, infectious process\n is not excluded. Findings: Frontal and lateral views of the chest were obtained. Dual-lead\n left-sided pacemaker is again seen with leads extending to the expected\n positions of the right atrium and right ventricle. The lungs are\n hyperinflated, with flattening of the diaphragms, suggesting chronic\n obstructive pulmonary disease. No pleural effusion or pneumothorax is seen. \n Slight increased opacity at the right lung base, best seen on the frontal view\n may relate to atelectasis, although in the appropriate clinical setting,\n infectious process is not excluded. No overt pulmonary edema is seen. Chest\n radiography is inappropriate for evaluation of pulmonary embolism. The aorta\n is calcified and tortuous. The cardiac silhouette is top normal to mildly\n enlarge.",
"image_path": [
"p18/p18929056/s58958987/5337ec0a-283bf318-55060740-77ac2e55-67b5f668.jpg"
],
"split": "test"
},
{
"id": "5d4e5d0a-add681d2-faf8a518-e0062eff-6554d2d2",
"study_id": 52398109,
"subject_id": 11512104,
"report": "impression: No acute cardiopulmonary process. Findings: Lung volumes are low. The heart remains mildly enlarged. Aortic knob is\n calcified. Mediastinal and hilar contours are unchanged, with a small hiatal\n hernia again noted. Pulmonary vascularity is within normal limits. No focal\n consolidation, pleural effusion or pneumothorax is present. Multiple clips\n are seen in the right upper quadrant compatible with prior cholecystectomy. \n Degenerative changes of the left glenohumeral joint are incompletely assessed.",
"image_path": [
"p11/p11512104/s52398109/5d4e5d0a-add681d2-faf8a518-e0062eff-6554d2d2.jpg"
],
"split": "test"
},
{
"id": "dc3b047f-54a16324-3e28091b-9d53d461-debc37f2",
"study_id": 54133721,
"subject_id": 12185775,
"report": "impression: Small bilateral pleural effusions. Findings: AP and lateral views of the chest. Low lung volumes. Two\n calcified granulomas in the left lung are unchanged. No focal consolidation\n or pneumothorax. There are small bilateral pleural effusions. \n Cardiomediastinal and hilar contours are stable. Degenerative changes are\n again seen in the spine.",
"image_path": [
"p12/p12185775/s54133721/dc3b047f-54a16324-3e28091b-9d53d461-debc37f2.jpg"
],
"split": "test"
},
{
"id": "ab15addd-7646ff4c-89b05c13-b4ea8bb6-22be4b16",
"study_id": 59941702,
"subject_id": 14841168,
"report": "impression: 1. Appropriately positioned orogastric tube and PICC line.\n 2. Ill-defined left basilar opacities, which likely represent atelectasis, but\n an underlying left lower lobe pneumonia cannot be excluded.\n 3. Stable enlargement of the cardiomediastinal silhouette and left hilum. Findings: There has been interval removal of the ETT and dobhoff. There is an\n orogastric tube seen with the tip and side hole below the diaphragm. There is\n a right-sided PICC line, which is unchanged in positioning.\n \n There are ill-defined opacities at the left base, which likely represent\n atelectasis, but an underlying lower lobe pneumonia cannot be excluded. The\n cardiomediastinal silhouette is enlarged but stable. The left hilum is\n prominent, likely reflecting pulmonary hypertension. The pulmonary\n vasculature is normal. No pleural effusion or pneumothorax is seen.",
"image_path": [
"p14/p14841168/s59941702/ab15addd-7646ff4c-89b05c13-b4ea8bb6-22be4b16.jpg"
],
"split": "test"
},
{
"id": "c8cfc832-b771f3f4-0862618d-c5b40b2a-86706006",
"study_id": 50848970,
"subject_id": 19715857,
"report": "impression: Moderate pulmonary edema. Findings: There is mild cardiomegaly and moderate pulmonary edema as well as\n small (right greater than left) pleural effusions. No pneumothorax. Severe\n degenerative changes at the right glenohumeral joint.",
"image_path": [
"p19/p19715857/s50848970/c8cfc832-b771f3f4-0862618d-c5b40b2a-86706006.jpg"
],
"split": "test"
},
{
"id": "3a2587b2-54d74fa2-bfaa41f8-376175a0-1ebd1aa5",
"study_id": 57153483,
"subject_id": 16435402,
"report": "impression: No change from ___. No new opacity.\n \n Requested wet read provided to Dr. ___ by phone ___. Findings: The lungs are well expanded. Lingular opacity and\n right basilar linear atelectasis are unchanged from ___. No new\n opacity is seen. There is no pleural effusion or pneumothorax. Heart size is\n normal. Mediastinal silhouette and hilar contours are normal.",
"image_path": [
"p16/p16435402/s57153483/3a2587b2-54d74fa2-bfaa41f8-376175a0-1ebd1aa5.jpg"
],
"split": "test"
},
{
"id": "8d70fba4-2de961f9-f5a521bd-99e41c4c-65e750ba",
"study_id": 57540712,
"subject_id": 13353878,
"report": "impression: 1. No acute cardiopulmonary process.\n 2. Paratracheal opacity most likely relates to enlarged thyroid gland seen on\n chest CT from ___, and followup recommendations per that CT remains. Findings: Frontal and lateral views of the chest were obtained. Previously\n seen left perihilar consolidation has resolved in the interval. The bilateral\n pleural effusions have also resolved. Paratracheal opacity in the upper\n thorax, likely secondary to goiter seen on chest CT from ___, in\n conjunction with mediastinal nodes also seen on that study. No focal\n consolidation, pleural effusion, or evidence of pneumothorax is seen. The\n cardiac silhouette is top normal to mildly enlarged, with left ventricular\n configuration. Mediastinal contours are stable. There is an old rib\n deformity/fracture of the posterior lateral left seventh rib, also seen on the\n prior chest CT.",
"image_path": [
"p13/p13353878/s57540712/8d70fba4-2de961f9-f5a521bd-99e41c4c-65e750ba.jpg"
],
"split": "test"
},
{
"id": "b740f79e-73da2f17-0d2dac03-2e639b9e-4e01c770",
"study_id": 53351384,
"subject_id": 13473495,
"report": "impression: Slight interval worsening of atelectasis at the left lung base. Stable\n moderate bilateral pleural effusions, left greater than right. Findings: The ET tube terminates 3.9 cm above the carina. There is an\n enteric tube which extends well below the diaphragm. Again seen is severe\n cardiomegaly, stable since at least ___. The lung volumes\n continued to be low with evidence of elevated pulmonary venous pressure and\n moderate bilateral pleural effusions, left greater than right. There appears\n to be slight interval worsening of the bibasilar atelectasis. There is no\n evidence of a pneumothorax. Note is again made of stable elevation of the\n right hemidiaphragmatic contour.",
"image_path": [
"p13/p13473495/s53351384/b740f79e-73da2f17-0d2dac03-2e639b9e-4e01c770.jpg"
],
"split": "test"
},
{
"id": "0d200bb3-f8564775-b6f65f57-a21dd9b7-d25d90ff",
"study_id": 52057634,
"subject_id": 15857729,
"report": "impression: No acute intrathoracic process. Findings: 2 views of the chest. Right PICC has been removed. The lungs are well\n expanded and clear. There is no pleural effusion or pneumothorax. The heart\n is normal in size with normal mediastinal contours.",
"image_path": [
"p15/p15857729/s52057634/0d200bb3-f8564775-b6f65f57-a21dd9b7-d25d90ff.jpg"
],
"split": "test"
},
{
"id": "306bc295-0e5c4259-e24a442d-9b2483b1-6478ee28",
"study_id": 57041570,
"subject_id": 14841168,
"report": "impression: Likely left basilar atelectasis. Otherwise, no acute\n cardiopulmonary process. Findings: Frontal and lateral views of the chest were obtained. The lateral\n views are somewhat underpenetrated in part due to the patient's overlying arm.\n Given this, there is persistent mild elevation of the right hemidiaphragm. \n Minimal left basilar atelectasis is seen. There is no focal consolidation. \n No large pleural effusion is seen. Slight blunting of the right costophrenic\n angle is chronic. The cardiac and mediastinal silhouettes are grossly stable\n as comparison with ___. No overt pulmonary edema is seen.",
"image_path": [
"p14/p14841168/s57041570/306bc295-0e5c4259-e24a442d-9b2483b1-6478ee28.jpg"
],
"split": "test"
},
{
"id": "0bb60711-8098a084-5f12d2bb-e8739a70-870e72a1",
"study_id": 51951386,
"subject_id": 16116557,
"report": "impression: No radiographic evidence for acute process. Findings: The lung fields are clear without focal consolidation, pleural\n effusion, or pneumothorax. Heart and mediastinal contours are within normal\n limits. Sternal wires and mitral valve replacement hardware are again seen.",
"image_path": [
"p16/p16116557/s51951386/0bb60711-8098a084-5f12d2bb-e8739a70-870e72a1.jpg"
],
"split": "test"
},
{
"id": "89761447-bc4663fb-0df82ab9-baf89987-3cefc06b",
"study_id": 58255867,
"subject_id": 14236258,
"report": "impression: Vague right mid/lower opacity, nonspecific the could represent infection in\n the proper clinical setting. Findings: Vague opacity projecting over the right mid/lower lung the which is new since\n prior. Elsewhere, the lungs are clear. There is no layering effusion. Cardiac\n silhouette is enlarged but similar in configuration. Multiple vascular stents\n are again noted projecting over the SVC, left brachiocephalic vein and left\n upper extremity. Surgical clips project over the lower neck. No acute osseous\n abnormalities.",
"image_path": [
"p14/p14236258/s58255867/89761447-bc4663fb-0df82ab9-baf89987-3cefc06b.jpg"
],
"split": "test"
},
{
"id": "b4a25932-1328eeb3-d6edac97-2f1a91ba-69790ccf",
"study_id": 55847451,
"subject_id": 16662264,
"report": "impression: Progression of previously existing bilateral parenchymal\n infiltrates and newly developed additional infiltrates are observed. In\n addition, bilateral pleural effusions have developed in the absence of\n evidence of pulmonary vascular congestion. Referring physician, ___\n ___, was paged for stat report at 1:20 p.m. Findings: PA and lateral chest views were obtained with patient in upright\n position. Analysis is performed in direct comparison with the next preceding\n similar study of ___. The heart size remains unchanged. The\n previously described pneumonic infiltrates located to the right middle lobe\n and left upper lobe lingula have progressed in extension. New additional\n parenchymal infiltrates are now also seen in the left upper lobe apical\n segment and a few scattered small patchy infiltrates are observed in the right\n hemithorax mid lung field as well. In addition, there is now clear blunting\n of the right and left lateral pleural sinuses extending into the posterior\n pleural sinuses as identified on the lateral view. The pulmonary vascular\n pattern does not show increased congestion in comparison with the previous\n study.",
"image_path": [
"p16/p16662264/s55847451/b4a25932-1328eeb3-d6edac97-2f1a91ba-69790ccf.jpg"
],
"split": "test"
},
{
"id": "762d904e-6d16b5e3-99ff54e0-002a0d8e-c7ab5157",
"study_id": 51351077,
"subject_id": 13475033,
"report": "impression: Prominent bilateral interstitial opacities could reflect interstitial lung\n disease versus interstitial edema. Please correlate clinically. Findings: PA and lateral views of the chest provided. Coronary stent projects over the\n heart. A stent projects over the right upper arm. There is again noted to be\n coarsened prominent interstitial markings throughout both lungs which could\n reflect underlying fibrosis versus interstitial pulmonary edema. No large\n effusion or pneumothorax. No convincing evidence for pneumonia. \n Cardiomediastinal silhouette is stable. Bony structures are intact. A\n chronic left clavicular midshaft deformity is noted.",
"image_path": [
"p13/p13475033/s51351077/762d904e-6d16b5e3-99ff54e0-002a0d8e-c7ab5157.jpg"
],
"split": "test"
},
{
"id": "0f513599-eb6bddc9-4306d15d-46c7c0c2-a3c6c854",
"study_id": 56013519,
"subject_id": 17163861,
"report": "impression: No acute cardiopulmonary process. Findings: Dual lead left-sided pacemaker is stable in position with leads extending to\n the expected positions of the right atrium and right ventricle. The patient\n is status post median sternotomy. There is minimal left base atelectasis. No\n focal consolidation, pleural effusion, or evidence of pneumothorax is seen. \n The cardiac and mediastinal silhouettes are stable. No displaced fracture is\n seen.",
"image_path": [
"p17/p17163861/s56013519/0f513599-eb6bddc9-4306d15d-46c7c0c2-a3c6c854.jpg"
],
"split": "test"
},
{
"id": "310e9e4c-47270425-45970e01-10edadcc-1789ecf5",
"study_id": 54745568,
"subject_id": 14608347,
"report": "impression: Retrocardiac opacity represents hiatal hernia. Findings: The cardiomediastinal contours are unchanged. The lungs\n demonstrate improved vascular congestion. In the retrocardiac region, there\n is a rounded density which is confirmed on the lateral view, compatible with a\n hiatal hernia. There is no pleural effusion or pneumothorax.",
"image_path": [
"p14/p14608347/s54745568/310e9e4c-47270425-45970e01-10edadcc-1789ecf5.jpg"
],
"split": "test"
},
{
"id": "6a92203f-216df921-4fce7d2a-acd7f2ac-ff08b6bf",
"study_id": 55036801,
"subject_id": 19907884,
"report": "impression: No evidence of acute cardiopulmonary process. Findings: Interval removal of a right-sided internal jugular central venous line.\n Multiple metallic clips overlying the superior mediastinum are unchanged in\n position. Lung volumes remain low leading to crowding of the bronchovascular\n structures. There is no evidence of focal consolidation, pleural effusion,\n pneumothorax, or pulmonary edema. The cardiomediastinal silhouette is within\n normal limits.",
"image_path": [
"p19/p19907884/s55036801/6a92203f-216df921-4fce7d2a-acd7f2ac-ff08b6bf.jpg"
],
"split": "test"
},
{
"id": "88fa75e4-2f2e9c03-71433ae3-1d8780f4-1e2eae3c",
"study_id": 54128066,
"subject_id": 12952223,
"report": "impression: Progression of moderate pulmonary edema. Findings: Moderate pulmonary edema has progressed since yesterday. Bibasilar\n atelectasis is unchanged. Mild cardimegally is similar. Median sternotomy\n wires are intact and mediastinal clips are in expected positions.",
"image_path": [
"p12/p12952223/s54128066/88fa75e4-2f2e9c03-71433ae3-1d8780f4-1e2eae3c.jpg"
],
"split": "test"
},
{
"id": "002ec547-39998a44-001fa06f-b2d03591-048c0d40",
"study_id": 59794546,
"subject_id": 14744884,
"report": "impression: No acute cardiopulmonary process. Bilateral low lung volumes\n with crowding of bronchovascular markings and bibasilar atelectasis. Findings: The cardiac, mediastinal and hilar contours\n are within normal limits. Both lungs show mildly low lung volumes with\n crowding of bronchovascular markings. Bibasilar atelectasis is noted. \n Subclavian/brachiocephalic venous stent is unchanged in position.\n \n No focal consolidation, pleural effusion or pneumothorax is noted.",
"image_path": [
"p14/p14744884/s59794546/002ec547-39998a44-001fa06f-b2d03591-048c0d40.jpg"
],
"split": "test"
},
{
"id": "7022a121-c39c1e71-7fc1c7f7-d24120be-62decb00",
"study_id": 54375943,
"subject_id": 19928916,
"report": "impression: No acute findings in the chest. Findings: Portable AP upright chest radiograph was obtained. Low lung\n volumes noted. Allowing for this, the lungs appear clear. No large effusion\n or pneumothorax is seen. The cardiomediastinal silhouette appears normal. A\n calcified granuloma projects over the right lateral mid lung. Bony structures\n are intact.",
"image_path": [
"p19/p19928916/s54375943/7022a121-c39c1e71-7fc1c7f7-d24120be-62decb00.jpg"
],
"split": "test"
},
{
"id": "b57f6693-0b6cfcff-9a77d958-c0a4c1f5-fab766d2",
"study_id": 50776901,
"subject_id": 16050730,
"report": "impression: Central pulmonary vascular engorgement without overt pulmonary edema. No\n focal consolidation to suggest pneumonia. Findings: There has been interval removal of a right internal jugular central venous\n catheter. Cardiac and mediastinal silhouettes are grossly stable given\n differences in patient position. Mild prominence of the hila suggest central\n pulmonary vascular engorgement with mild peribronchial cuffing. No definite\n focal consolidation is seen. No large pleural effusion or pneumothorax is\n seen.",
"image_path": [
"p16/p16050730/s50776901/b57f6693-0b6cfcff-9a77d958-c0a4c1f5-fab766d2.jpg"
],
"split": "test"
},
{
"id": "dc93422b-fd5ec685-19eb4eba-fb31f8d0-b60d8b47",
"study_id": 58836461,
"subject_id": 15192710,
"report": "impression: Small left pleural effusion and improving atelectasis, but no\n pneumothorax. Findings: The cardiomediastinal and hilar contours are normal. Subtle linear\n horizontally oriented opacities in the left costophrenic angle appear improved\n compared to prior exams and likely reflect the sequelae of resolving\n atelectasis. There is no pneumothorax. A small left pleural effusion is\n seen.",
"image_path": [
"p15/p15192710/s58836461/dc93422b-fd5ec685-19eb4eba-fb31f8d0-b60d8b47.jpg"
],
"split": "test"
},
{
"id": "9df33cee-a5533c4d-56048d41-edb2923b-6b01ac1f",
"study_id": 50749866,
"subject_id": 12595991,
"report": "impression: Improved pulmonary edema. Findings: Moderate to severe cardiomegaly is stable. Pacer leads are in standard\n position. ET tube is in standard position. Left IJ catheter tip is in the mid\n SVC . Right PICC is in unchanged position. NG tube tip is out of view below\n the diaphragm. Vascular congestion has improved. Bibasilar atelectasis have\n improved. Bilateral effusions right greater than left are unchanged",
"image_path": [
"p12/p12595991/s50749866/9df33cee-a5533c4d-56048d41-edb2923b-6b01ac1f.jpg"
],
"split": "test"
},
{
"id": "17799b54-f6da063b-4b089f2b-c496ec31-de79a706",
"study_id": 53458437,
"subject_id": 14295224,
"report": "impression: Right upper lobe infiltrate has improved since ___. There is no\n new lung consolidation. Findings: The patient has prior history of gastric pull-through with radiation therapy\n for esophageal cancer.\n \n Right upper lobe consolidation in posterior segment has slightly improved. \n The lungs are hyperinflated. 6 mm right lower lobe nodule is unchanged since\n ___. Small right pleural effusion is stable since ___. There is\n no pneumothorax. Mediastinal and cardiac contours are normal.",
"image_path": [
"p14/p14295224/s53458437/17799b54-f6da063b-4b089f2b-c496ec31-de79a706.jpg"
],
"split": "test"
}
]
================================================
FILE: data/test/report/pmc-oa_test.json
================================================
[
{
"id": 0,
"image": "PMC2874782_F1_64665.jpg",
"report": "Representative immunostaining of CA enzymes in MBs. Panel A shows no immunoreaction for CA IX, whereas the tumour in panel B is strongly positive. Panel C demonstrates CA XII-positive immunoreactivity in tumour cells. In panel D, CA II-positive immunostaining is confined to the endothelium of small blood vessels (arrows). All magnifications ×400.",
"metadata": {}
},
{
"id": 1,
"image": "PMC3008732_pone-0015623-g001_81993.jpg",
"report": "Lentivirus-shOPN decreases metastasis to the lung.(A) Gross morphological examination of the lung after aerosol delivery of shOPN for 1 or 2 months. White circles indicate neoplastic nodules observed in the lung. (B) Histopathological examination of lung after aerosol delivery of shOPN for 1 or 2 months. Magnification (×200) scale bar: 50 µm.",
"metadata": {}
},
{
"id": 2,
"image": "PMC2879550_fig3_65398.jpg",
"report": "Stomach biopsy: (a) H&EX40 (Olympus BX40)—DLBCL, (b) antibody staining CD 20+, (c) antibody staining BCL6+, (d) antibody staining Ki67+.",
"metadata": {}
},
{
"id": 3,
"image": "PMC2862961_fig3_63363.jpg",
"report": "\nC. parapsilosis adhesion to the gingival epithelial monolayer culture. Human gingival cells were grown up to 80% confluence, pulsed with C. parapsilosis or C. albicans, and incubated for 6 hours with or without serum. Following this culture period, the supernatant containing nonattached Candida was discarded, and the cultures were washed and stained with Cristal violet. Representative photographs are presented. Magnification: 250×.",
"metadata": {}
},
{
"id": 4,
"image": "PMC2704215_F4_41003.jpg",
"report": "A wetting agent is present beyond the edge of the swarm. Colony photography using reflected light (A, B) illustrating the presence of a wetting agent (arrows) preceding the spreading colony on (A) FW medium with succinate and NH4Cl as C, N source. B) Colony spread is limited by 500 μg/L CR, but wetting agent spreads as above. C) Drop collapse assay using dilute methylene blue solution showing the reduced surface tension in the wetting agent zone (left of the black line).",
"metadata": {}
},
{
"id": 5,
"image": "PMC3012668_F4_82618.jpg",
"report": "Immunodetection of CA1 in the synovial membranes of AS, RA and OA patients. CA1 was significantly detected with a strong immunosignal in AS synovial tissue. Original magnification: 100X and 200X. The picture at the bottom is a negative control prepared with AS synovial tissue that was not treated with primary antibody.",
"metadata": {}
},
{
"id": 6,
"image": "PMC2633049_pone-0004392-g001_33496.jpg",
"report": "Morphology of hypothalamic-derived NS, phase-contrast images.A, Dividing cells after 2 days in vitro (2DIV). B, Fetal hypothalamic NS after 7DIV. C, Adult hypothalamic NS after 7DIV. Scale bars: 50 μm.",
"metadata": {}
},
{
"id": 7,
"image": "PMC1262738_F1_3551.jpg",
"report": "Lg-SIL : cellularity is satisfactory (Papanicolaou stain, high magnification – 20x objective, Papspin® system). HCII was positive.",
"metadata": {}
},
{
"id": 8,
"image": "PMC2890595_F4_67047.jpg",
"report": "Mixing with 10% wild-type cells begins to rescue the culmination defect of cpnA- cells. Wild-type and cpnA- Dictyostelium cells were mixed at various ratios, plated on black filters in starvation buffer at 5 × 107 cells/mL, and allowed to develop for 24 hours. The wild-type cell percentage is given in the lower right of each image. Images were taken using a Leica dissecting microscope at 20× magnification (scale bar = 1 mm). Arrows (C-F) point to stalks.",
"metadata": {}
},
{
"id": 9,
"image": "PMC2519073_F3_26947.jpg",
"report": "The structure of the leaf using modified 2PLSM.",
"metadata": {}
},
{
"id": 10,
"image": "PMC3017546_pone-0014497-g004_83409.jpg",
"report": "NKp46 immunostaining.Patients with an overexpression of IL-18 and with low (A) or high level of TWEAK (B). Magnification is 20X (first column) and 40X (second column). ep: epithelium, s: stroma, gl: glands, sa: spiral arteries.",
"metadata": {}
},
{
"id": 11,
"image": "PMC2754491_F3_47132.jpg",
"report": "Distribution of CFP-TPs in the mammalian cells HeLa and L929 observed under a confocal microscope (TCS SP2, Leica). The images a and b show DAPI staining nucleus of cells HeLa and L929; the images c and d, e and f, g and h, and i and j show CFP-TP1, CFP-TP2, CFP-TP3, and CFP-TP4 expressions in the HeLa and L929 cells, respectively.",
"metadata": {}
},
{
"id": 12,
"image": "PMC2780448_F1_51550.jpg",
"report": "Liver fibrosis. The liver section stained with Masson's trichrome from a control (A), compared with a BDI patient (B) showed significant deposition of ECM proteins (blue stain) in B.",
"metadata": {}
},
{
"id": 13,
"image": "PMC2376294_fig2_22441.jpg",
"report": "Immunhistochemical staining of serial tissue sections of a nodular melanoma, tumour thickness according to Breslow 1.4 mm, Clark's level IV. The PTEN/MMAC1 protein was detected in melanoma cells and was not restricted to tumour associated macrophages. (a) Hematoxylin Eosin, (b) HMB45, (c) CD68, (d) PTEN/MMAC1 staining (all magnification 25×, nickel enhanced DAB reaction resulting in black signals).",
"metadata": {}
},
{
"id": 14,
"image": "PMC2668105_CPT-62-05-0387-f04_37192.jpg",
"report": "Acute eosinophilic pneumonia. (A) When many eosinophils are visible in the airspaces in a patient with acute lung disease, a diagnosis of acute eosinophilic pneumonia is appropriate. (B) Organisation in alveolar spaces, and rarely hyaline membranes, may be present. (A,B) H&E stain, 100× original magnification.",
"metadata": {}
},
{
"id": 15,
"image": "PMC2830938_F6_58242.jpg",
"report": "Expression of TrxR in normal, BH, DCIS and IBC tissue. A. Tissues were subjected to IHC using a TrxR-specific antibody. Representative slides are shown at 40× magnification. B. The relative mean intensity was determined from 6-8 images for each BH (n = 16), DCIS (n = 15) or IBC (n = 20) section and is shown graphically. The intensity of normal mammary tissue is equal to one (dashed line).",
"metadata": {}
},
{
"id": 16,
"image": "PMC2685395_F1_38929.jpg",
"report": "Dissected crown tissue from 6 week old plants that have experienced a gradual decline in temperature and light: a) Solstice, a winter variety; b) Paragon, a spring variety. The two images are at the same magnification.",
"metadata": {}
},
{
"id": 17,
"image": "PMC2737141_pone-0007020-g003_44753.jpg",
"report": "Sub-cellular (co-)localization of MAD2B and RAN.Endogenous MAD2B, RAN and γ-tubulin (mitotic spindle) are shown in green, red and white, respectively. DAPI staining (blue) was used to mark nuclei and chromosomes. The overlay of the different signals (Merge) reveals a near perfect co-localization of the respective proteins at the mitotic spindle (arrows). Images were captured using confocal laser scanning microscopy.",
"metadata": {}
},
{
"id": 18,
"image": "PMC2276502_F2_19785.jpg",
"report": "Electric microscopic observation of A549 cells infected with YS001. Bacteria attached (arrows) to the cell and the microvilli (arrow heads) of the cell are recognized. Bars, 1 μm (A) and 0.5 μm (B).",
"metadata": {}
},
{
"id": 19,
"image": "PMC2924897_pone-0012304-g006_71850.jpg",
"report": "Representative micrographs of U251 (A-D) and U87 (E-H) cells grown in the presence of BK and IK1 blockers.Cells were grown in the serum-free OptiMEM media supplemented with serum substitute B27. The BK blocker paxilline (10 µM) and the IK1 inhibitor clotrimazole (10 µM) were added as indicated. Images of the cells were captured ∼48 hrs after addition of channel blockers using Hoffman modulation contrast optics in Olympus IX71 microscope at 10×10 magnification.",
"metadata": {}
},
{
"id": 20,
"image": "PMC2859758_F3_62873.jpg",
"report": "In situ hybridization. Panels A-C shows results from Sense probe negative controls with no detectable nuclear staining. Panels D-F the positive cells of tissue sections probed with HPV-L1, EBV-EBER, and KSHV-ORF72 showed dark brown staining of the nucleus. The probes did not detect all viruses in all tumor cells, however, HPV, EBV, and KSHV were detected in some regions. Panels G-I shows a higher magnification of 60× compared to panels D-F which showed magnification of 40×.",
"metadata": {}
},
{
"id": 21,
"image": "PMC2910694_F1_69939.jpg",
"report": "Protein Expression by Immunofluorescence. Pretreatment biopsies revealed increased pAkt/Akt ratio in tumor specimens as compared with non malignant pancreatic tissue. No such trends were noted for pErk/Erk or pmTOR/mTOR. Immunofluorescence results depicted above.",
"metadata": {}
},
{
"id": 22,
"image": "PMC2688674_fig10_39340.jpg",
"report": "E2 and F12 are required for IEV morphogenesis. Electron micrographs showing the peri-nuclear wrapping compartment in WR-, ΔE2L- and ΔF12L-infected HeLa cells at 8 h post infection. In WR-infected cells IMV (black arrows) and wrapped brick-shaped IEV (yellow arrows) are readily observed. In contrast, in ΔE2L- and ΔF12L-infected cells, IEV are partially wrapped (red arrows) and embedded in a dense tubular network of membranes. Scale bars = 2 μm top panels and 0.5 μm bottom panels.",
"metadata": {}
},
{
"id": 23,
"image": "PMC1783847_F2_9085.jpg",
"report": "Distribution of VP2 within infected and transfected Vero cells by fluorescence microscopy. A) Cells infected with BTV-10, B-E) transfected cells expressing B) VP2, C) VP2-GFP, D) GFP-VP2 and E) GFP only. VP2 in A and B were detected with anti VP2 monoclonal antibody (rabbit) and either FITC (A) or TRITC (B) conjugated secondary antibody. C-E were visualised based on GFP fluorescence. Expression of full-length, tagged VP2 variants was confirmed by western blot using an anti-GFP antibody (F).",
"metadata": {}
},
{
"id": 24,
"image": "PMC3012079_pone-0015680-g003_82587.jpg",
"report": "Histological changes in liver upon DENV-2 infection in mice.WT or KO mice were infected i.p. with 10 LD50 of DENV-2 and then sacrificed at day 6 for tissue samples. Hematoxylin & Eosin stained liver sections from non-infected and DENV-2 infected WT, CCR1–/–, CCR2–/– and CCR4–/– mice, showing different degrees of congestion, hemorrhage, hepatocyte degeneration and necrosis. Each slide presented in the panel is representative of at least 10 different fields (n = 5–6 mice). Magnification: 400X.",
"metadata": {}
},
{
"id": 25,
"image": "PMC2881123_F6_65648.jpg",
"report": "Different oligomeric states of KLH2 (a-e) and Leptoxis carinata hemocyanin (a'-e'). (a-d; a'-d') Class sum images of negatively stained single particles collected from electron micrographs. (e, e') 3D models shown as longitudinal section through the cylinder wall to reveal the fundamentally different collar complexes. Note that the flattening effect is more obvious in KLH2 (upper panel).",
"metadata": {}
},
{
"id": 26,
"image": "PMC2584631_F2_30303.jpg",
"report": "StAR protein localization. StAR protein expression was analyzed using a polyclonal rabbit anti-mouse StAR antibody on Day 16 (a) and 22 (b) of pregnancy and Day 3 post-partum (c). Immunoreactive-StAR was observed across all days in the CL compartment, specifically in luteal cells (lc). Sections treated without the primary antibody showed no immunostaining (d). The staining pattern and intensity were consistent between immunohistochemical runs (n = 4). [Magnification 400×]",
"metadata": {}
},
{
"id": 27,
"image": "PMC3025911_pone-0016007-g002_85302.jpg",
"report": "Apical localization of EVs in MCF-7/MR cells.Cells were transiently transfected with GPI-CFP and VSVG-YFP constructs (green fluorescence), reacted with anti-ABCG2 antibody BXP-53 (red fluorescence) and DAPI and analyzed using Zeiss inverted Cell-Observer microscope at a magnification of ×630. Arrows denote the subcellular localization of GPI-CFP (A–F) and VSVG-YFP (G–L).",
"metadata": {}
},
{
"id": 28,
"image": "PMC2409854_fig1_23826.jpg",
"report": "Representative immunohistochemical staining patterns for ET-1 (A), ETAR (B) and ETBR (C) in breast carcinomas. For each marker, a sample with weak (left), moderate (middle), and strong (right) cytoplasmic immunostaining is shown.",
"metadata": {}
},
{
"id": 29,
"image": "PMC2951342_pone-0013075-g003_75452.jpg",
"report": "Mapping the active regions of the murine and human NXNL1 and NXNL2 promoter constructs using electroporation of mouse retinal explants.Retinal explants were electroporated at P0 with the GFP expression vector driven by different fragments of the Nxnl promoters and cultured for 5 days in vitro (DIV5). (A) NXNL1 (B) Nxnl1 (C) NXNL2 (D) Nxnl2. The intensity of fluorescence of a GFP reporter under the control of the chicken β-actin promoter (pCIG) is provided for comparison.",
"metadata": {}
},
{
"id": 30,
"image": "PMC1634748_F1_7620.jpg",
"report": "Subcutaneous bile lake with associated xanthogranulomatous reaction (H&E stain, magnification ×100).",
"metadata": {}
},
{
"id": 31,
"image": "PMC1779380_F3_8663.jpg",
"report": "Confocal micrographs of dendritic cells and macrophages pulsed with type II collagen (CII). (a-c) Macrophages and (d-f) dendritic cells were incubated in the (a,b,d,e) presence or (c,f) absence of 200 μg/ml CII for 30 minutes, stained for CII expression and analyzed by confocal microscopy. Magnification ×630, and bars denote (a) 6.63 μm, (b) 8.09 μm, (c) 5.0 μm, (d) 4.27 μm, (e) 4.64 μm and (f) 4.0 μm. More than 50 cells were examined for each treatment.",
"metadata": {}
},
{
"id": 32,
"image": "PMC2500098_F1_26404.jpg",
"report": "Colour distances for ROI detection applied to biopsies. a) Original Image, b) RGB (Euclidean), c) HSI (NBS), d) CIEL*a*b (CIEDE2000). Colour distances for ROI detection applied to biopsies.",
"metadata": {}
},
{
"id": 33,
"image": "PMC2212626_F1_16583.jpg",
"report": "Immunohistochemical staining of macrophage and dendritic cell infiltration in colorectal cancer. (A) CD68 and (B) CD163 expression of the macrophages (inset: double labeling CD163 (red)/S100 (brown) distinguishes CD163+ macrophages from S100+ DC). Dendritic cell populations with expression of (C) S100, (D) CD11c, (E) CD208, (F) CD209, (G) CD123 and (H) CD1a (inset: Langerin/CD207). (magnification ×200, inset ×400).",
"metadata": {}
},
{
"id": 34,
"image": "PMC3065459_pone-0018053-g001_91207.jpg",
"report": "Tissue sampling.Example of tissue sampling from anesthetized animals using a sterile trephine punch.",
"metadata": {}
},
{
"id": 35,
"image": "PMC2946604_fig2_74894.jpg",
"report": "(a) Histological examination of the partially resected tumor revealed carcinoid with muscularis propria involvement (H&E ×4). (b) Carcinoid was consisted of uniform cells with round-shaped nuclei with ribbon-like structure (H&E ×40). (c), (d) The tumor cells showed immunoreactivity for synaptophysin (synaptophysin, (c) ×4, (d) ×40).",
"metadata": {}
},
{
"id": 36,
"image": "PMC3076443_pone-0018777-g003_92315.jpg",
"report": "Lung histopathology and germination of conidia in mice exposed to Aspergillus conidia.A–F, H&E staining of mouse lung tissue. G–I, GMS staining of lung tissue. A,D,G, saline controls. B,E,H, A. versicolor, C,F,I, A. fumigatus. A–C 4× magnification, D–F, 40× magnification. G–I, 100× magnification. Data depicted are representative samples of 5 mice per group with one lung section analyzed per animal.",
"metadata": {}
},
{
"id": 37,
"image": "PMC3078923_pone-0018799-g004_92733.jpg",
"report": "Eggs of S. mansoni visualised within a colon biopsy crush preparation by bright-field microscopy.(A) Viable mature eggs containing fully developed miracidia (←), an empty egg shell (↑) of a previously hatched miracidium and a dead egg with diffuse contents (→). (B) Dead eggs without dark and granular contents (→). (C) Egg shell with an almost completely hatched miracidium (←) that is trapped within the tissue.",
"metadata": {}
},
{
"id": 38,
"image": "PMC3056777_pone-0017899-g003_90076.jpg",
"report": "Expression of peripheral nerves markers in matrigel after mASCs transplantation.A–E. - Immunofluorescent staining of frozen matrigel sections with antibodies against neurofilament200 (A.), GAP43 (B.), tyrosine hydroxylase (C.), peripherin (D) or with non-specific IgGs (red fluorescence). Nerve fibers are indicated by arrows. Nuclei are counterstained with DAPI (blue fluorescence).",
"metadata": {}
},
{
"id": 39,
"image": "PMC2981848_F0001_78513.jpg",
"report": "Low- and high-power (inset) fields of duodenal and ileal biopsies showing intraepithelial and subepithelial lymphocytic infiltrates",
"metadata": {}
},
{
"id": 40,
"image": "PMC2697132_F6_40087.jpg",
"report": "CRF induces the phosphorylation of FAK. MCF7 cells were treated with CRF (10-8 M) or vehicle (control) for 3 hours, stained with phospho-FAK antibody and analyzed with confocal microscopy. Result is representative of three independent experiments.",
"metadata": {}
},
{
"id": 41,
"image": "PMC2613149_F7_31952.jpg",
"report": "Pathological sections specimens. (7) Low magnification showing encapsulated papillary tumor with thin fibrovascular stalk, covered by tall mucinous moderately dysplastic epithelium (8). Higher magnification demonstrates area with oncocitic pattern (9). The immunohistochemical test showed a diffuse CK7+ (10) and apomucines MUC5AC (11) and MUC6 (12) positivity in more than 50% of neoplastic cells.",
"metadata": {}
},
{
"id": 42,
"image": "PMC2671840_pone-0005412-g004_37635.jpg",
"report": "BBK32 (21–205) effects on Fn matrix assembled by NHDFs.Cells were incubated for 48 hours and then incubated with 5 µM BBK32 (21–205), 5 µM anastellin, or 5 µM FnbpA peptide D3. Treated cells were incubated for 20 hours and probed with Alexa Fluor 488-anti-Fn and monoclonal antibody IST 9. Images were taken using LSM 510 Confocal Microscope, objective 63X/1.4 oil. Bar = 10 µm.",
"metadata": {}
},
{
"id": 43,
"image": "PMC1884170_F1_11231.jpg",
"report": "Targeting of NF-E2p45 to chromatin compartment but displacing of GATA-1 from mitotic chromosomes in mitotic cells. Cells were stained with antibodies against proteins indicated on the left followed by FITC-conjugated secondary antibodies (Left) and PI (Center). Right is the merge of both images. Examples of interphase cells and mitotic cells of different stages from MEL cells are shown.",
"metadata": {}
},
{
"id": 44,
"image": "PMC1804299_F3_9722.jpg",
"report": "Rat pretreated with OSO, slight erosion of\nthe gastric mucosa is observed. Arrow: H&E; magnification, X 100.",
"metadata": {}
},
{
"id": 45,
"image": "PMC524523_F4_709.jpg",
"report": "Detection of Su(Fu) in prostate cancer specimens. Su(Fu) antibodies (Santa Cruz Biotechnology Cat# 10933) recognized only one single band (54-Kd) in D283 cells (A). Following treatment of a specific SiRNA of Su(Fu), the endogenous Su(Fu) band was greatly reduced (B). Immunohistostaining with Su(Fu) antibodies in prostate cancer specimens revealed positive (C, in red, 200×), negative (D, 200×) or weak staining (E, red, 200×).",
"metadata": {}
},
{
"id": 46,
"image": "PMC2600683_fig1_31185.jpg",
"report": "HE staining and IHC staining for Snail and E-cadherin in a human ACC ( × 10). (A) HE staining with tumour invading the surrounding fatty tissue. (B) Consecutive section with IHC staining for Snail showing Snail-expressing cells invading the fatty tissue. (C) Same specimen demonstrating the invasive front at a higher magnification ( × 40).",
"metadata": {}
},
{
"id": 47,
"image": "PMC2746600_fig2_46310.jpg",
"report": "Representative images of tumour microvasculature in animals treated with SU5416 (25 mg kg−1 per day, A,B) and with vehicle (C,D) at day 6 after tumour cell implantation. Corresponding regions by means of OPS imaging (A,C) and fluorescence microscopy (B,D). Arrows indicate non perfused vessels.",
"metadata": {}
},
{
"id": 48,
"image": "PMC2670270_F3_37447.jpg",
"report": "Morphological examination by phase contrast micrography in the late log phase of growth (original magnification ×200)-HN2A oropharyngeal primary (on plastic).",
"metadata": {}
},
{
"id": 49,
"image": "PMC3001427_F1_80937.jpg",
"report": "Images represent analyses taken at a Zeiss Axiovert 40C inverted microscope and an Axiocamera MRC5 (Zeiss, Germany) of spheres observed with phase contrast while culturing of dissociated mouse or guinea pig cochleas, with either bFGF or TGFα, as indicated. Scale bar 50 μm.",
"metadata": {}
},
{
"id": 50,
"image": "PMC2503985_F3_26498.jpg",
"report": "Images of the immunohistochemical assays: PECAM-1 on endothelial cells attached to titanium after (A) 24 hours, (B) 7 days and (C) 14 days, and to control surface after (D) 24 hours, (E) 7 days and (F) 14 days.",
"metadata": {}
},
{
"id": 51,
"image": "PMC1852111_F1_10398.jpg",
"report": "Hematoxilin and eosin-stained sections showing solid sheets of squamous cells infiltrating the right lobe of the prostate (a; original magnification 10×) and the left lobe (b, c; original magnification 10× and 20×, respectively). Mytotic activity may also be observed (d; original magnification 40×).",
"metadata": {}
},
{
"id": 52,
"image": "PMC2034570_F2_14200.jpg",
"report": "photomicrograph: 2A)Microscopic examination revealed hyperchromatic neoplastic cells arranged in solid nests, and anastomosing trabeculae with ductal formation. (H&E × 200) 2B) Microscopic examination also revealed irregular cribriform glandular structures (featuring an adenoid cystic carcinoma-like pattern) with irregular infiltrative tumor margins. (H&E × 200) 2C) Perineural invasion and lymphovascular space permeation were noted upon microscopic examination. (H&E × 200).",
"metadata": {}
},
{
"id": 53,
"image": "PMC1794515_F5_9434.jpg",
"report": "Comparison of immunohistochemical detection of activation markers. Analysis of representative areas of synovial tissue samples taken from patients with end-stage osteoarthritis (OA) or refractory rheumatoid arthritis (RA) is shown. Expression pattern and staining intensity of RA samples represent the stronger intensity of synovial inflammation when compared with OA samples. Magnification, ×400. FAP, fibroblast activation protein; MMP, matrix metalloproteinase.",
"metadata": {}
},
{
"id": 54,
"image": "PMC2287181_F5_19936.jpg",
"report": "Activated lymphocytes were incubated for 2 h with 1 μM of SHPR190 labelled with Alexa 488. Cells were then washed and maintained in HBS buffer for examination by confocal microscopy. Visualisation was performed either by fluorescence (top panel) or by light transmission (bottom panel).",
"metadata": {}
},
{
"id": 55,
"image": "PMC2736977_F2_44726.jpg",
"report": "Lack of BCCIP expression in brain tumors. Serial tissue sections were stained for GFAP and BCCIP separately. Both GFAP and BCCIP are stained in brown color. Hematoxylin (blue) was used to counter stain the nuclei. Shown are example brain tissues stained with antibodies against GFAP and BCCIP (magnification is 40 × 10). Top panel is a representative non-tumor section. The middle panel is an example section of BCCIP positive tumor, and the bottom panel shows a BCCIP negative tumor section.",
"metadata": {}
},
{
"id": 56,
"image": "PMC2751800_f4_46906.jpg",
"report": "Effect of blue light on mitochondrial shape. The figure shows electron micrographs of sections from untreated ARPE-19 cells (A, D), irradiated cells with an output at 0.3 mW/cm2 (B, E) and 1 mW/cm2 (C, F) for 72 h (Bar=1 μm). Irradiated cells showed mitochondria with unusually elongated profiles.",
"metadata": {}
},
{
"id": 57,
"image": "PMC2837050_F5_58852.jpg",
"report": "NG2-glia cells express JAM-A. Confocal images of immunostainings of vibratome sections from the corpus callosum labeled with the indicated markers (upper boxes) are shown. In (B) the cell body labeled with an arrow in (A) is shown at higher magnification. In (C) negative controls, where only one primary antibody but the two secondary antibodies anti-mouse-Alexa-568 nm (M-Alexa-568) and anti-rabbit-Alexa-488 nm (Rb-Alexa-488) have been used, are shown. Scale bars: 10 μm",
"metadata": {}
},
{
"id": 58,
"image": "PMC2832730_fig4_58481.jpg",
"report": "Growth plate of the right tibia (A) and higher magnification images in the Si-deprived (B1 and B2), Si-supplemented (C1 and C2) and standard rodent stock feed-fed (D1 and D2) groups. Growth plates from two animals (1 and 2) are shown as representative for each group. Growth plate thickness was reduced, while chondrocyte cell density appears to be slightly increased in the Si-deprived group (B1 and B2) compared to the Si-supplemented and standard rodent stock feed-fed reference groups.",
"metadata": {}
},
{
"id": 59,
"image": "PMC2803960_F3_54324.jpg",
"report": "Histopathology. a. Immunohistochemical cytoplasmic positivity for a1-fetoprotein, × 400. b. Immunohistochemical \"canalicular\" pattern of staining for polyclonal carcinoembryonic antigen (CEA), × 400 (arrows).",
"metadata": {}
},
{
"id": 60,
"image": "PMC2714065_F1_41860.jpg",
"report": "Immunohistochemical analysis of p16INK4A expression using monoclonal antibody clone JC8 in tissue microarray cores from cervix biopsies with normal epithelium (A, B), CIN1 (C, D), CIN2 (E, F), CIN3 (G, H) and invasive squamous carcinoma (I, J). The normal epithelial and stromal cells are negative (A – B). Strong, distinct, diffuse staining of both nuclei and cytoplasm is seen in the dysplastic/neoplastic epithelium (C – J).",
"metadata": {}
},
{
"id": 61,
"image": "PMC1868777_pone-0000478-g005_10879.jpg",
"report": "Downregulation of centromeric and kinetochore proteins causes severe defects in chromosome congression and segregation.Mitotic phenotypes of D-mel wild-type cells transfected with dsRNAs targeting kinetochore proteins as indicated and stained with anti-α-tubulin antibody (to mark microtubules; red) and DAPI (to mark DNA; blue). Bar represents 5 µm.",
"metadata": {}
},
{
"id": 62,
"image": "PMC1253525_F1_3378.jpg",
"report": "a y b: Papamicolaou; c: biopsy; d: CD45; e: neuron specific enolase; f: vimentin.",
"metadata": {}
},
{
"id": 63,
"image": "PMC1804207_fig01_9702.jpg",
"report": "Histological features of abdominal skin obtained from perinatal autopsy cases with and without histological chorioamnionitis. Epidermis and dermis do not show significant changes in a fetus without histological chorioamnionitis (A,C). An inflammatory infiltrate is evident in the epidermis and dermis of a fetus with histological chorioamnionitis (B,D). The dermoepidermal junction is studded with CD15+ neutrophils.",
"metadata": {}
},
{
"id": 64,
"image": "PMC2667496_F2_37129.jpg",
"report": "Location of activated AMPK in developing cysts by whole mount immunohistochemistry. Decapsulated embryos developing for 2, 4, 6, 8, 10, and 12 h were fixed in 4% paraformaldehyde, permeated by 0.1% Triton X-100, incubated with phospho-AMPK (Thr172) antibody (a – f), and subsequently detected with the AP-conjugated secondary antibody by NBT/BCIP staining. e' and f' represent control embryos that were not incubated with the primary antibody. Embryos are shown at the same magnification.",
"metadata": {}
},
{
"id": 65,
"image": "PMC2830950_F5_58260.jpg",
"report": "Pathological findings: Hematopoietic locations. A: Capillarized sinusoids of a bone biopsy with an inflammatory surrounding (HES ×400). B: CD31 positivity of the endothelial lining of capillarized sinusoids (×200). C: Spleen dilated sinusoids (smooth muscle actin ×100). D: Spleen larger cysts lined by a continuous layer of CD31 endothelial cells (CD31 × 100).",
"metadata": {}
},
{
"id": 66,
"image": "PMC1808458_F2_9832.jpg",
"report": "Photomicrograph of the resected neurofibroma showing spindle cells with characteristic elongated, wavy nuclei. (20× magnification, Haematoxylin and Eosin)",
"metadata": {}
},
{
"id": 67,
"image": "PMC2867796_F8_63694.jpg",
"report": "Expression of globinpromotor::GFP fusions. (A) glb-26::GFP expression, (B) glb-26::GFP expression in head mesodermal cell, (C) glb-26::GFP expression in stomato-intestinal muscle, (D) glb-1::GFP expression, (E) glb-1::GFP expression in the head, (F) glb-1::GFP expression in the tail, background fluorescence is also visible in the posterior intestine.",
"metadata": {}
},
{
"id": 68,
"image": "PMC2867813_F2_63699.jpg",
"report": "TEM observation of granulosa cells exposed to calcium phosphate nanoparticles. Cells were exposed during 72 h to 100 μM of nanoparticles. Nanoparticles were internalized in cells and localized in cytoplasms, mostly in membranate compartments, including lysosome and mitochondria, thecal organelles (arrow). The scale bar in the image is 500 nm.",
"metadata": {}
},
{
"id": 69,
"image": "PMC3017954_fig2_83564.jpg",
"report": "Analysis of chitin and glucan distribution in BA-treated cells: fluorescence of calcofluor white (top) and aniline blue (bottom) stained cells. At BA concentrations of 0.4%, chitin-rich—and to a lesser extent, glucan-rich—material accumulates at the bud neck. The thickening of septa is evident particularly between cells in a chain.",
"metadata": {}
},
{
"id": 70,
"image": "PMC2631459_F3_33230.jpg",
"report": "Representative example of human breast cancer specimens from TMA3 that expressed either low (left panel) or high (right panel) eIF4E. Matching specimens from the same patient are shown for c-Myc, cyclin D1, ODC, TLK1B, and VEGF (200 × magnification).",
"metadata": {}
},
{
"id": 71,
"image": "PMC2695428_F3_39915.jpg",
"report": "Fibroblast surface protein immunocytochemistry of primary cells from duodenal endoscopic biopsies from celiac (upper panel) and non celiac (lower panel) patients; DAPI counterstained cellular nuclei.",
"metadata": {}
},
{
"id": 72,
"image": "PMC548319_F6_1248.jpg",
"report": "Immunocytochemistry determination of IREG1. Hippocampal neurons and SH-SY5Y cells, labeled with rabbit anti-IREG1 antibody and with Alexa-546-conjugated goat anti-rabbit IgG, were imaged in a confocal microscope. Shown are representative fields of cells cultured at different iron concentrations. Note the preferentially cytosolic distribution of IREG1.",
"metadata": {}
},
{
"id": 73,
"image": "PMC2575403_ppat-1000204-g001_29592.jpg",
"report": "Granulomas from TB patients display many M.tb-containing FMs surrounding the necrotic center.Thin sections of lymph node biopsy samples from 10 tuberculous patients were stained and analyzed. A) Haematoxylin and Eosin staining, original magnification ×12. B, C) Oil red-O staining, original magnification ×200 (B) and ×1000 (C). D) Ziehl-Nielsen staining (×1000). G: granuloma, N: necrosis, I: interface. Arrow: Giant Langhans cell (B), M.tb (D).",
"metadata": {}
},
{
"id": 74,
"image": "PMC2716360_F1_42254.jpg",
"report": "Cells submitted to FISH (A) and immunohistochemistry (B) assays. A1 (case 14), A2 (case 5) and A3 (case 6): interphase nuclei presenting chr17 monosomy (green signal) with one copy of TP53 (red signal), and nuclei presenting chr17 disomy with one or two copies of TP53 – 1000× magnification; B1 (case 14) and B2 (case 17): tissue with nuclear p53 immunoreactivity (brown stain) – 400× and 100× magnification, respectively; B3 (case 6): tissue without p53 immunoreactivity – 400× magnification.",
"metadata": {}
},
{
"id": 75,
"image": "PMC2696764_fig1_40069.jpg",
"report": "Immunohistochemical images of invasive cancer with high (A) and low (B) tumour-associated trypsin inhibitor (TATI) score and expression of TATI in adjacent non-malignant mucosa (C).",
"metadata": {}
},
{
"id": 76,
"image": "PMC3014818_f03_82926.jpg",
"report": "Overwintering site of Laccotrephes japonensis in the ditch around (a) rice fields, and (b) ditch. Overwintering adult labeled with color dots on the forewing for individual identification. High quality figures are available online.",
"metadata": {}
},
{
"id": 77,
"image": "PMC1783662_F3_9062.jpg",
"report": "Microscopic appearance of ancient schwannoma. a) spindle cells in an Antoni type A area; a red arrow indicates a large bizarre hyperchromatic nucleus b) Antoni B areas consisting of spindle cells within a loose myxoid matrix, c) occasional pleomorphic nuclei within Antoni A areas, and d) positive S100 immunohistochemical staining.",
"metadata": {}
},
{
"id": 78,
"image": "PMC2957392_F1_76356.jpg",
"report": "Fluorescent distribution of PdhS-mCherry fusion in stationary growth phase E. coli. A, early stationary phase; B, middle stationary phase; C, late stationary phase. White arrows point to refractile bodies that are only present in the bacteria from the late stationary culture phase. Scale bar: 2 μm. DIC means differential interference contrast (Nomarski). All micrographic images were taken with the same magnification.",
"metadata": {}
},
{
"id": 79,
"image": "PMC2837314_fig2_58890.jpg",
"report": "SEM photograph of the surface of white MTA immersed in PBS for 10 days, showing precipitates of various morphologies. Wavelength-dispersive X-ray spectroscopy analysis revealed that the precipitates contained Ca and P as their main elemental components.",
"metadata": {}
},
{
"id": 80,
"image": "PMC2409183_fig3_23620.jpg",
"report": "The E218Q mutant of basigin, but not the E218R mutant, is correctly targeted to the plasma membrane of COS cells. COS cells were co-transfected with MCT1-c-CFP and basigin-c-YFP constructs containing the mutations indicated and live cell imaging performed as described under ‘Methods’. This Figure is reproduced in colour in Molecular Membrane Biology online.",
"metadata": {}
},
{
"id": 81,
"image": "PMC2846841_F5_60718.jpg",
"report": "Azorubine coloration, ATPase and SDH activities revelation and immunohistochemical analysis results on a identical serial cross-section of TB muscle. A. Azorubine coloration. B. ATPase and SDH activities. C. Immunohistochemical results obtained with F365B9, S515F4 and S58H2 antibodies. Scale of the cross-section : 600 μm (length)/400 μm (height).",
"metadata": {}
},
{
"id": 82,
"image": "PMC2807157_F0003_54988.jpg",
"report": "FISH technique: A single-stranded probe was used to hybridize with a specific DNA sequence of the sample. In this case, we used the LSI CHOP (12q13) Dual Color, Break Apart Rearrangement Probe (Abbott Laboratories), which showed the nuclei of normal cells with two fusion signals, whereas the signal pattern of abnormal cells was one orange, one green, and one fusion signal",
"metadata": {}
},
{
"id": 83,
"image": "PMC2249593_F2_17979.jpg",
"report": "Immunohistochemical examination of Bcl-2 family members and death receptors. Immunohistochemistry was performed to measure the expression of Bak, Bax, Bcl-2, Bcl-XL, TRAIL-R1/DR4 and TRAIL-R2/DR5 in tumor tissues derived from control and/or treated mice on week 6.",
"metadata": {}
},
{
"id": 84,
"image": "PMC2928796_F1_72210.jpg",
"report": "Representative images from immunohistochemical analysis of survivin expression in normal and cancerous prostatic tissue. A, normal prostate. B, prostate cancer. The images were obtained at 200× magnification.",
"metadata": {}
},
{
"id": 85,
"image": "PMC3055888_pone-0017660-g003_89747.jpg",
"report": "\nfgfr2 expression pattern in early stages of chick lung development.Representative examples of whole mount in situ hybridization (A–C) and sections of hybridized lungs (D–F). fgfr2 is present in distal epithelium of main bronchus (arrow) and secondary bronchi (asterisks); peri-epithelial mesenchyme of the main bronchus (dark arrowheads); open arrowheads, proximal epithelium. Magnification: A/C - 5×; D, F - 20×; E - 10×.",
"metadata": {}
},
{
"id": 86,
"image": "PMC3022012_pone-0014498-g001_84363.jpg",
"report": "Dynamic morphology of Ramos B cells.Selected frames from live microscopic imaging of RTX-Al488 coated Ramos cells (Videos S1). Ramos cells were able to adhere to the substratum by the formation of a uropod as seen at the first time of observation (0 min), and at 10 and 15 minutes afterwards. RTX-Al488 (green) was enriched at uropods, while being depleted from the opposite, mobile end. Scale bar 10 µm.",
"metadata": {}
},
{
"id": 87,
"image": "PMC2100046_F4_15086.jpg",
"report": "Chloroacetate esterase staining of heart and lung paraffin sections. Representative tissue samples for untreated healthy animals, animals undergoing CPB, and animals undergoing CPB with LIM. Magnification is 200-fold.",
"metadata": {}
},
{
"id": 88,
"image": "PMC2500179_ppat-1000135-g008_26421.jpg",
"report": "EGFP expression in An. gambiae F1 adults infected with wild-type AgDNV (from pBAgα) and EGFP-transducing virions (from pAgActinGFP), which demonstrates transmission of transducing virions between mosquito generations.A–C: EGFP expression in abdomen, D: EGFP expression in head, E: EGFP expression in maxillary palp.",
"metadata": {}
},
{
"id": 89,
"image": "PMC2588660_pcbi-1000251-g004_30745.jpg",
"report": "Model-based reconstruction of neuronal branching from 3D two-photon image\nstacks.Depicted at the example of an HSE dendrite (A,B) and of a VS2 cell (C,D).\nLeft, maximum intensity projections of the image stacks containing\nfluorescent cells. Right, overlaid reconstructed branching in red.",
"metadata": {}
},
{
"id": 90,
"image": "PMC3057974_pone-0017315-g005_90153.jpg",
"report": "Binding of F1SBPs to Caco-2 cells in vitro detected by flow cytometry (A–D) and confocal microcopy (E–F).A: FITC-streptavidin; B and E: UEA-FITC 0.5 µg/ml; C: Blon_0375-FITC 1 µg/ml; D and F: Blon_2347-FITC 1 µg/ml; G: Blon_2347-FITC 1 µg/ml and DAPI (blue); H: fixed Caco-2 cells coincubated with 1 µg/ml Blon_0375-FITC; I: Caco-2 cells incubated for 10 min with 1 µg/ml Blon_0375-FITC and stained with DAPI.",
"metadata": {}
},
{
"id": 91,
"image": "PMC2784441_F5_51931.jpg",
"report": "Interactions of tauPRD with G-actin observed by atomic force microscopy. Skeletal muscle (M) and platelet (P) G-actin were incubated with tauPRD in binding buffer at 37°C for 30 min and then aliquots were taken for observation by atomic force microscopy as indicated. Bars in panels are 50 nm.",
"metadata": {}
},
{
"id": 92,
"image": "PMC2173904_F7_15771.jpg",
"report": "Electron microscopy of untreated or MnTBAP-treated HIV-1 infected macrophages. Untreated macrophages show accumulation of many mature particles, at different stages of maturation, in cytoplasmatic vacuoles and in the extracellular space. By contrast in MnTBAP (30 μM) treated macrophages no viral particles are found. This observation support the hypothesis that MnTBAP treatment is able to prevent enveloped and unenveloped virions production.",
"metadata": {}
},
{
"id": 93,
"image": "PMC1550268_ppat-0020085-g003_6623.jpg",
"report": "Polarity of Nuclear Actin Filaments Reflect the Overall Polarity of the CellNeurons were stained with AF568-phalloidin, anti-GM130 to stain the Golgi. GFP-VP26 is visualized by direct fluorescence. Each image is a 2-D projection from four consecutive layers in a confocal image stack, taken 0.5 μm apart. Scale bar = 20 μm. Top two rows show polarized SCG neurons with one axon. Bottom row shows a single SCG neuron with two axons emanating from opposite sides of the cell body.",
"metadata": {}
},
{
"id": 94,
"image": "PMC2242829_ppat-0040043-g001_17597.jpg",
"report": "Multi-Drug–Resistant P. aeruginosa Clinical Isolates Display Unusual Appendage-Like Structures on the Cell SurfaceTransmission electron microscopy (TEM) images of MDR virulent clinical isolates at magnification of 15,000 × 1.4.(A) Strain MDR1.(B) Strain MDR13.(C) Strain MDR25.(D) Strain MDR26.Novel appendage-like structures are shown by black arrows. For comparison, flagella are indicated by grey arrows.",
"metadata": {}
},
{
"id": 95,
"image": "PMC2740040_fig-003_45245.jpg",
"report": "\nA & B: Pleural biopsy, H&E stain : There are nests, cords, and gland-like structures present (A). Tumor cells are composed of epithelial-like cells with eosinophilic cytoplasm, marked nuclear pleomorphism, macronucleoli and occasional mitotic figures (B). C & D: Immunohistochemistry: Tumor cells are focally positive for calretinin (C) and CK5/6 (D). \nE & F: Immunohistochemistry: Tumor cells are strongly positive for CK7 (E) and negative for TTF-1 (F).",
"metadata": {}
},
{
"id": 96,
"image": "PMC2527786_fig1_27192.jpg",
"report": "Association between the presence of HPV type 33 and Id-1 overexpression in human invasive breast cancer in a sample patient. We noted that E6 expression of HPV type 33 is correlated with Id-1 overexpression in invasive breast cancer using tissue microarray analysis. Magnification is × 200. The presence of HPV type 33 was confirmed by PCR using specific primers for the E6 gene of this virus.",
"metadata": {}
},
{
"id": 97,
"image": "PMC2724395_F3_43199.jpg",
"report": "Immunohistochemical analysis of p-AKT, PI3K-110 alpha subunit protein expression and PTEN in epithelial ovarian carcinoma (EOC). (i) p-AKT over expression was observed along with (iii) low PTEN expressionand (v) over expression of PI3K-110 alpha in EOC TMA specimen and, (ii) Low expression for p-AKT was seen along with (iv) high PTEN expression and (vi) reduced expression for PI3K-110 alpha in EOC TMA specimen. 20 × magnifications with the inset showing a 100 × magnified view of the same.",
"metadata": {}
},
{
"id": 98,
"image": "PMC2586367_pbio-0060292-g009_30522.jpg",
"report": "Function of Selected Mouse Orthologs of Genes Showing Lipid Storage Phenotypes in Drosophila Cells(A–F and M–R) AML12 or 3T3-L1 cells (G–L), with (B–F and H–R), or without (A and G) oleic acid and stained for nuclei (Hoechst 33342) and lipid (BODIPY493/503). Cells were transfected with ALLStars negative control siRNA (control) or the siRNAs targeting the indicated genes. Drosophila homologs are given (parentheses). Scale bar in (A) represents 50 μm.",
"metadata": {}
},
{
"id": 99,
"image": "PMC2778170_fig6_50997.jpg",
"report": "The PET-patch on the left atrial side (arrows) is completely covered by fibrous tissue and endothelium without major inflammatory reactions. Magnification 16×, Richardson blue staining. PET: polyethylenterephtalat.",
"metadata": {}
},
{
"id": 100,
"image": "PMC1661684_pbio-0040423-g004_7844.jpg",
"report": "Fluorescence Visualization of an ER Marker after UPR Induction(A) Cells treated with the UPR-inducing drug DTT (+DTT) or with no drug were visualized using a fusion protein between the translocon component Sec61 and the red-fluorescent protein “cherry.” Top panels show untreated cells, and bottom panels show representative UPR-induced cells.(B) Representative images showing UPR-induced cells that contain ERAs (indicated by arrows).",
"metadata": {}
},
{
"id": 101,
"image": "PMC3049559_fig1_89036.jpg",
"report": "Immunohistochemical characterisation of CXC-chemokine and its receptor expression in colorectal tissue. (A) Representative high-powered images (magnification × 200) illustrating weak (left panel) and strong (right panel) immunoreactivity to antibodies used to characterize the expression of CXCR1, CXCR2 and CXCL1 in colorectal biopsy tissue. (B) Representative low-powered images showing differential expression of CXCL8 within the inflammatory cells surrounding the colorectal epithelial tissue.",
"metadata": {}
},
{
"id": 102,
"image": "PMC2427016_F1_24257.jpg",
"report": "Peripheral T-cell lymphoma, unspecified (submental lymph node biopsy). A, The H&E section demonstrates expansion of the interfollicular T-cells (low magnification); B. The infiltrating T-cells show atypia and clear cytoplasm (high magnification); C, Paraffin immunoperoxidase staining reveals the lymphoma cells are positive for CD4; D. Reactive CD8-positive T-cells are also present.",
"metadata": {}
},
{
"id": 103,
"image": "PMC3061870_pone-0017867-g006_90667.jpg",
"report": "Aberrant differentiation in the skin of RASSF9−/− mice—K5 (red).(A) Frozen sections of dorsal skins of WT (+/+) and RASSF9−/− (−/−) mice were immunostained with red fluorescence for K5 in 4-dpp mice. Scale bar = 100 µm. (B) Images at higher magnification. Scale bar = 40 µm. Blue, DAPI staining of cell nuclei.",
"metadata": {}
},
{
"id": 104,
"image": "PMC2954984_F2_75986.jpg",
"report": "H2O2 -induced cell death and neurite retraction in differentiated PC12-GFP and PC12-SH2B1β cells. PC12-GFP cells (A, C, E) and PC12-SH2B1β cells (B, D, F) were differentiated using 50 ng/ml NGF for 7 days. After overnight incubation in serum-free medium containing 50 ng/ml NGF, both cell lines were treated with 0, 100 or 200 μM H2O2 for 24 h. Representative images were shown (400× magnification).",
"metadata": {}
},
{
"id": 105,
"image": "PMC2887077_F1_66363.jpg",
"report": "Representative photographs of portal tracts stained with hematoxylin/eosin (upper panel) used for grading of liver sections in biliary atresia based on the presence of inflammatory cells (scale bar on photo 3 = 50 μm). The lower panels depict liver sections stained with trichrome for staging based on the extent of fibrosis (scale bar on photo 3 = 250 μm).",
"metadata": {}
},
{
"id": 106,
"image": "PMC2788242_pone-0008213-g002_52368.jpg",
"report": "Immunohistochemical identification of VEGF isoforms.(a) Negative controls with blue labeling corresponding to haematoxylin labeled nucleus (arrows). (b) VEGF-A, VEGF-B, VEGF-C and VEGF-D positive cells from human thymus adipose tissue (arrows). (c) VEGF-A, VEGF-B, VEGF-C and VEGF-D positive cells from human subcutaneous adipose tissue (arrows). Positive cells shown with brown labeling.",
"metadata": {}
},
{
"id": 107,
"image": "PMC2862514_F0003_63311.jpg",
"report": "Biopsy specimen of the PNET tumor showing tumor cells arranged in nests. These cells are perivascular in arrangement. Cells are PAS positive. (H and E, ×40)",
"metadata": {}
},
{
"id": 108,
"image": "PMC2880434_F3_65482.jpg",
"report": "ZsGreen-cODC+ cells are a subpopulation of CD24low/-/CD44+ stem cell-containing population and lead to tumor growth. (A) Confluent MCF-7-ZsGreen-cODC monolayer (top panel) and spheres (bottom panels). ZsGreen-cODC+ cells are enriched in mammospheres. (B) Immunofluorescence of CD24 (red, top panel) and CD44 (red, bottom panel) reveals an overlap between ZsGreen-cODC-positive cells and the subpopulation CD24low/-/CD44+ in MCF-7-ZsGreen-cODC mammospheres.",
"metadata": {}
},
{
"id": 109,
"image": "PMC2360109_fig3_21043.jpg",
"report": "Composition of clustered infiltrates in adenocarcinoma lesions (PAC), adjacent benign tissue (peri-PAC) and specimens of nodular hyperplasia of the prostate gland (NHPG). Successive tissue sections were reacted to antibodies recognising common (CD45) and subset-specific (CD3, CD4, CD8 – T lymphocytes, CD20 – B lymphocytes) markers of leucocytes. Magnification × 200.",
"metadata": {}
},
{
"id": 110,
"image": "PMC2764571_F3_48266.jpg",
"report": "Retinoic acid (RA) cannot override the inhibition of skeletal myogenesis by β-Cat/EnR. P19[control] (A, B, E, F) and P19[β-Cat/EnR] (C, D, G, H) cells were aggregated in the presence of 0.8% dimethylsulfoxide (DMSO) with (E-H) and without (A-D) 10 nM RA. Cells were fixed on day 9 of differentiation for immunofluorescence with MF20 antibody (B, D, F, H) and counter stained with Hoechst dye (A, C, E, G). Magnification is 160×.",
"metadata": {}
},
{
"id": 111,
"image": "PMC3048869_pone-0017306-g004_88991.jpg",
"report": "Induction of tissue necrosis in the BNYVV inoculated leaf area of\ntransgenic N. benthamiana plant lines expressing\nSP/HrpZPsph.A) Non-transgenic plant. B)\nSP/HrpZPsph-expressing plant. The inset\nshows the tissue necrosis localized in the inoculated leaf area of a\nrepresentative resistant T1 plant at 3–4 dpi.",
"metadata": {}
},
{
"id": 112,
"image": "PMC2064921_F1_14676.jpg",
"report": "The 3D view of gradient vector field and diffused gradient vector field with elastic deformation transformation of a slice cropped from a 3D cell nuclei image. (a). A slice of the 3D image. (b). The original gradient vector field. (c). The diffused gradient flow field with elastic deformation transformation. Obviously, the diffused vector field with elastic deformation transformation smoothly flows toward the central areas of cell nuclei. (d). Zoomed view of (b). (e). Zoomed view of (c).",
"metadata": {}
},
{
"id": 113,
"image": "PMC2593789_pone-0002950-g001_30917.jpg",
"report": "Middle ear infection by pneumococcal strain ST556.(A) Detection of ST556 encapsulation by transmission electron microscopy. (B) Detection of ST556 infection in the middle ears. Chinchillas were infected with bioluminescent pneumococci via tympanotomy and monitored daily for bacterial burden by bioluminescence. The scales on the right indicate the levels of photon counts.",
"metadata": {}
},
{
"id": 114,
"image": "PMC535552_F2_825.jpg",
"report": "Delayed chlorophyll fluorescence images. Luminescence from leaves of Arabidopsis (A) and Tradescantia (B). Images are 5-minute exposures taken as soon as possible after transfer of leaves to the equipment. A conventional photograph of the Tradescantia leaf imaged in (B) is shown to illustrate the pattern of variegation (C).",
"metadata": {}
},
{
"id": 115,
"image": "PMC2702298_F9_40781.jpg",
"report": "Scanning Electron Microscopy of Cadmium treated lung. A, No lobular appearances were observed under lower magnification. B, Alveolar space was getting narrowed in treated lung, compared to the normal one. C, Lobular appearances were prominent at higher magnification. D, Narrow edicular spaces signify the increasement of cell density. Ibuprofen showed no effect to revert the structural deformity.",
"metadata": {}
},
{
"id": 116,
"image": "PMC2638156_F1_34216.jpg",
"report": "Microscopy of CHO-perRed peroxisomal marker cells. A. Bright field and fluorescent images of CHO-perRed cells obtained by fluorescent microscopy (original magnification, 100 ×). B. Laser scanning confocal microscopy images (original magnification, 630 ×) of GFP-fused Acaa1 (green) and DsRed2 (red). The merged images (yellow) indicate co-localization of Acaa1 and DsRed2.",
"metadata": {}
},
{
"id": 117,
"image": "PMC2883207_F0001_65877.jpg",
"report": "SEM image of rifampicin-loaded microcapsules.Scanning electron micrographs of rifampicin-loaded microcapsules (MC1) prepared by ionic gelation process taken at scope magnifications of ×500.",
"metadata": {}
},
{
"id": 118,
"image": "PMC3021568_f10_84288.jpg",
"report": "Images of microvilli in in vitro reconstituted corneal epithelium. Scanning electron microscope images showing Control (A) and EDEV-HCE tissue induced for 24 h (B) with treatments with different tear substitutes (C-Hyalistil®; D-Etacortilen®; E-Xiloial®; F-TSP 0,5%®; G-Optive®). Two μm magnification.",
"metadata": {}
},
{
"id": 119,
"image": "PMC2635605_f7-ijms-9-2044_33755.jpg",
"report": "Confocal microscopy images of HeLa (A, C) and HEK 293 (B, D) cells in 0.5 and 24 hrs after treating with 10 nM GSH-QDs (top row: a-e), 10 nM GSH-QDs and 1.6 ng/mL Hoechst 33342 (middle row: f-j), and 10 nM GSH-QDs and 0.2 nM ER-TrackerTM Green (bottom row: k-o). Hoechst 33342 and ER-TrackerTM Green stain nuclei and endoplasmic reticulum, respectively. Scale bars in figures show 20 μm length.",
"metadata": {}
},
{
"id": 120,
"image": "PMC2741442_F2_45804.jpg",
"report": "Ultrastructural evaluation of muscular biopsy from a PSSM affected Norman Cob horse #49. (A) Transversal section. (B) Longitudinal section. Severe mitochondrial (m) and myofibrillar (f) loss due to abnormal accumulation of granular material (arrowhead) resembling glycogen. Some myelinic bodies (arrow) were present that demonstrated mitochondrial degeneration. A nucleus is indicated (n).",
"metadata": {}
},
{
"id": 121,
"image": "PMC2649142_F1_35177.jpg",
"report": "Microscopic image of the duodenal mucosal biopsy. Duodenal mucosal biopsy showing subtotal villous atrophy, lymphocyte infiltration and crypt hyperplasia.",
"metadata": {}
},
{
"id": 122,
"image": "PMC2734747_F2_44540.jpg",
"report": "Mixed solitary bronchial papilloma. At this magnification, fibrovascular cores are lined by squamous and glandular epithelium. Hematoxylin-eosin stain; magnification × 100.",
"metadata": {}
},
{
"id": 123,
"image": "PMC2903487_pone-0011560-g006_68677.jpg",
"report": "Imaging a specific locus and its chromosome territory in living human cells.Representative images of three different nuclei revealing the relative distribution of chromosome 11 and the 11q13 locus 135 minutes post-mitosis. Maximal projections of 3D stacks of chromosome 11 (green, left) and lacO repeats (red, middle) or merged (right) at 11q13 in 3 different positions: outside main territory (A), edge of territory (B) and inside territory (C). Bar 10 µm.",
"metadata": {}
},
{
"id": 124,
"image": "PMC3009745_pone-0015748-g001_82281.jpg",
"report": "Treatment with rhGas6 reduces Oil-Red-O positive deposits after cuprizone intoxication.A–F, corpus callosum of mouse brain after PBS treatment. Extensive deposition of Oil-Red- O positive droplets can be seen (arrows). Brain sections from mice treated with 400 ng/ml (G and J), 4 µg/ml (H and K), and 40 µg/ml (I and L) of rhGas6 demonstrate a beneficial effect for all tested rhGas6 doses. Arrows indicate the clearance of debris from the corpus callosum. Low and high magnification, ×50 and ×400.",
"metadata": {}
},
{
"id": 125,
"image": "PMC2064969_F2_14741.jpg",
"report": "Deconvoluted, 3-dimensional rendition of multiple-stacked acquisitions of HBD-1 in the epidermis. A nucleus from the volume rendered image is then extracted and wire framed, allowing visualization of the HBD-1 within the nucleus, shown at a high magnification in the final panel (magnification × 4000).",
"metadata": {}
},
{
"id": 126,
"image": "PMC2587915_ppat-1000240-g002_30635.jpg",
"report": "Virus replication is sustained and distribution is more widespread within the lungs of MyD88−/− mice as compared to WT mice.5 µM paraffin-embedded sections derived from the lung tissue of WT and MyD88−/− mice were hybridized with an 35S-UTP-labeled riboprobe complementary to either the N gene of SARS-CoV (Urbani) or to the EBER2 gene from Epstein-Barr virus (data not shown). Images (magnification, 100×) are representative of at least three mice.",
"metadata": {}
},
{
"id": 127,
"image": "PMC2621132_F4_32384.jpg",
"report": "Higher power view of the lesion showing irregularly arranged bland spindle cells in the lamina propria (hematoxylin-eosin stain, original magnification ×200).",
"metadata": {}
},
{
"id": 128,
"image": "PMC2873392_F2_64456.jpg",
"report": "Confocal micrographs showing the expression of PI Synthase, PI-3 Kinase and Cyclin D1 in AMOL cells after treatment with ST. Cells grown on coverslips were treated with ST (10 μg/ml) for 48 h and immunolabelled with respective antibodies followed by FITC conjugated secondary antibody (Green fluorescence) and nuclei were counterstained with PI (red fluorescence). Original Magnification × 200.",
"metadata": {}
},
{
"id": 129,
"image": "PMC2936354_F4_73129.jpg",
"report": "Electron micrographs of R. leguminosarum VF39SM fla mutants stained with uranyl acetate. Inset pictures show the flagellar filaments at higher magnification. (a) flaA- (b) flaB- (c) flaC- (d) flaD- (e) flaE- (f) flaH- (g) flaG- (h) flaB/C/D- (i) flaA/B/C/D-. Bars: 500 nm for cells with flagella; 100 nm for inset pictures.",
"metadata": {}
},
{
"id": 130,
"image": "PMC2360493_fig1_21258.jpg",
"report": "Representative images of ING2 immunohistochemical staining in human melanocytic lesions. Strong ING2 expression in adjacent normal epidermis (A), normal nevi (B), dysplastic nevi (C), and weak ING2 staining in primary melanoma (D) and metastatic melanoma (E). Arrows indicate strong staining in melanocyte. Magnification, × 400.",
"metadata": {}
},
{
"id": 131,
"image": "PMC2777152_F3_50723.jpg",
"report": "EGFR expression was assessed in tumor sections using immunohistochemistry. The brown colored membrane staining indicates EGFR positive immunoreactivity. (A: Control, B: PDT, C: Erbitux and D: PDT +Erbitux). Magnification: 630×.",
"metadata": {}
},
{
"id": 132,
"image": "PMC2612005_F6_31878.jpg",
"report": "PSA-NCAM in the human adult medulla oblongata, caudal level (case 10). A: panoramic view of the right side spinal trigeminal nucleus, caudal part (Sp5C), at the boundary with the spinal cord. B: control immunostaining on a section semiconsecutive to that in A. C: higher magnification of the area framed in A; arrow points to a labelled neuron in the spinal nucleus substantia gelatinosa (sg). sp5, spinal trigeminal tract; fc, fasciculus cuneatus. Scale bars: A, B = 500 μm; D = 100 μm.",
"metadata": {}
},
{
"id": 133,
"image": "PMC2266753_F4_18780.jpg",
"report": "Fluorescence pattern of pig spermatozoa stained with FITC-PNA + PI for the assessment of acrosome status and sperm viability. Dead cells showing nuclear red PI fluorescence: C-D. Live cells without PI staining: A acrosome-reacted cells with uniform green FITC-PNA fluorescence of acrosome cap; B: acrosome-unreacted cells with no staining of acrosomal cap (original magnification ×1000).",
"metadata": {}
},
{
"id": 134,
"image": "PMC2704220_F1_41008.jpg",
"report": "CXCR4 expression in HCC TMAs. Representative CXCR4 staining. (A): CXCR4 staining in a single tissue core with a 1-mm diameter (× 50). (B): Cytoplasmic CXCR4 staining. (C): Nuclear CXCR4 staining. (D-G): Examples of weak (+) (D), moderate (++) (E), strong (+++) (F), and very strong staining (++++) (G). All images are × 200 magnification unless otherwise noted.",
"metadata": {}
},
{
"id": 135,
"image": "PMC2614982_F1_32243.jpg",
"report": "Scanning electron micrographs of a zirconia disk (left) showing occasionally pores on the smooth surface and a titanium disk (right) with rough surface and frequent pores and grooves of different size (2 kV, magnification 500-fold).",
"metadata": {}
},
{
"id": 136,
"image": "PMC3030506_F2_85758.jpg",
"report": "Effects of MWCNT on macrophages in vitro - light microscopy observations. Representative light microscopy images of RAW 264.7 cells exposed for 24 h to culture medium alone (Control) or 100 μg/ml of carbon black (CB), crocidolite fibres, NT1, NT2 or NT3. Original magnification: x 20. Abbreviations are the same as in Figure 1.",
"metadata": {}
},
{
"id": 137,
"image": "PMC2974734_F3_78098.jpg",
"report": "Immunohistochemistry of mast cells, 5-HT, and IL-6 (magnification 60×). A-F. FFPE GI mucosa block sectioned and immunostained for mast cells, 5-HT, and IL-6. A-B. Increased mast cell counts per HPF in non-inflammatory biopsies compared to inflammatory biopsies. C-D. No significant difference between phenotypes in 5-HT immunoreactivity. E-F. Increased IL-6 immunoreactivity of inflammatory biopsies compared to non-inflammatory biopsies.",
"metadata": {}
},
{
"id": 138,
"image": "PMC2993023_fig2_79828.jpg",
"report": "\nCase 1: The histopathology of the first biopsy specimen confirmed the diagnosis of BCC.",
"metadata": {}
},
{
"id": 139,
"image": "PMC2890388_F11_67000.jpg",
"report": "Microscopic appearance of burned skin on the 8th day.",
"metadata": {}
},
{
"id": 140,
"image": "PMC3075449_F0002_92293.jpg",
"report": "SEM observation of SBMP after three-month storage time. A(adhesive), C(resin composite) D (dentin), RT(resin tags)",
"metadata": {}
},
{
"id": 141,
"image": "PMC2850327_F1_61285.jpg",
"report": "Endogenous Bmp2 is detectable in the nuclei of three cultured cell lines. (a) Non-transfected 10T1/2 mesenchymal cells, BALB/3T3 fibroblasts, and RCS cells were cultured on slides and immunostained using an anti-Bmp2 antibody (green). Nuclei were stained with TO-PRO-3 (red), and cells were examined by laser confocal microscopy. (b) Antibody specificity was verified by preabsorbing anti-Bmp2 antibody with recombinant human BMP-2 before immunostaining.",
"metadata": {}
},
{
"id": 142,
"image": "PMC3023714_pone-0016023-g002_84764.jpg",
"report": "Immunohistochemical detection of NIS protein expression in 5 µM sections of selected tissues from patient cohort.(a) Thyroid tissue (positive control) (400×), (b) Antibody free Fibroadenoma (negative control) (200×), (c) Fibroadenoma (400×). Also shown are breast cancer epithelial subtypes Luminal A (d), Luminal B (e), Her2 (f) and Basal (g) at 400× magnification.",
"metadata": {}
},
{
"id": 143,
"image": "PMC2633001_F1_33465.jpg",
"report": "A representative immunohistochemical section of the resected primary tumor – diffuse c-KIT staining.",
"metadata": {}
},
{
"id": 144,
"image": "PMC2686160_pone-0005786-g002_39049.jpg",
"report": "Inhibition of T-cell migration.Open bars represent LacZ animals and black bars represent SOD3 animals. Infiltration of CD3+ lymphocytes was inhibited in SOD3 animals 10 days after injury remaining at the level seen at earlier 3-day time point (20× magnification).",
"metadata": {}
},
{
"id": 145,
"image": "PMC2551608_F5_27954.jpg",
"report": "Microscopic phenotype of A. gossypii wild-type, Δprs2,4 and Δprs3 strains. Micelia of the A. gossypii wild-type, Δprs2,4 and Δprs3 strains grown on liquid rich medium were visualized under optical microscopy at 12, 24 and 48 hours of culture. Bar indicates 1 mm.",
"metadata": {}
},
{
"id": 146,
"image": "PMC2700454_F0001_40499.jpg",
"report": "Case of idiopathic BOOP, shown on low power [magnification × 10] - pale staining areas of elongated branching fibrosis, involving bronchiolar lumen and peribronchial airspaces [solid arrow]. The alveolar septae [inset] shows mild chronic inflammation",
"metadata": {}
},
{
"id": 147,
"image": "PMC2676252_F2_37916.jpg",
"report": "Reorganization of microtububules and centrosome protein in cells expressing myogenic differentiation markers. Culture of mouse myoblasts containing undifferentiated (u) cells, and cells that started to differentiate (d). The centrosome protein PCM-1 is stained in red, DNA is stained in blue. In green is marked (A) tubulin, (B) the differentiation marker 'embryonic myosin', (C) the differentiation marker myogenin, (D) the proliferation marker Ki-67. Bars, 10 μm. Identical magnifications in A-C.",
"metadata": {}
},
{
"id": 148,
"image": "PMC1896151_F2_11774.jpg",
"report": "Distribution and downregulation of miRNA in TG. TG tissues were obtained from animals inflamed by CFA for 4 hr and in situ hybridization was performed with 5' biotin labeled LNA probes according to the protocol recommended by the manufacturer (Exiqon). Bound probes were detected by Cy3-streptavidin for green fluorescence while the tracer rhodamine-conjugated dextran produced red fluorescence. White arrowhead indicates tracer labeled cells.",
"metadata": {}
},
{
"id": 149,
"image": "PMC2841131_F1_59509.jpg",
"report": "Histological appearance of IDP of the left breast in low power field, ×40 (A). Two-cell pattern lined by luminal cuboidal cells and a distinct outer layer of myoepithelial cells under higher magnification, ×200 (B).",
"metadata": {}
},
{
"id": 150,
"image": "PMC2360416_fig1_21214.jpg",
"report": "Immunofluorescence staining of cells using anti-MUC1 antibody (CD227). (A, B) DIC microscopy images show clusters of Capan-1 and HPAF-II cell lines and (C) DIC images show U-87 MG (negative control) cells without clustering. (D, E, F) Fluorescence microscopy images show relative extent of FITC-conjugated anti-MUC1 antibody (CD227) associated with cells. (G, H, I) Superimposed images confirm areas of antibody location with respect to each cellular cluster (× 20 magnification).",
"metadata": {}
},
{
"id": 151,
"image": "PMC2862246_f3_63260.jpg",
"report": "In vivo confocal microscopic findings of the affected individual. A: Superficial epithelial cells and B: basal epithelial cells with a well-demarcated cell border and the presence of reflective material are seen. C: Stroma/endothelium is not apparent.",
"metadata": {}
},
{
"id": 152,
"image": "PMC2823723_F2_57134.jpg",
"report": "Biofilm production of serotype M18 GAS and M18::covS mutant strains. The GAS strains were grown on a polystyrene well surface or plastic coverslips, coated with human collagen type I, for 72 h in static culture. A. Safranin assay. B. Scanning electron microscopy. Different magnifications are presented as follows: 200×, 2000×, 5000× (from lower to upper panel, respectively). The P-value of differences as determined by two-tailed paired Student's t test is shown above the columns in panel A.",
"metadata": {}
},
{
"id": 153,
"image": "PMC2266936_F2_18904.jpg",
"report": "Morphological change of human glioblastoma cells by gamma-irradiation. Phase microphotographs of cultured radio-resistant tumor cells of A172, GBM2, and U87MG cells (× 200 magnification) at various culture passages after gamma-radiation. Scale bars, 50 μm.",
"metadata": {}
},
{
"id": 154,
"image": "PMC2927528_F5_72102.jpg",
"report": "Electron micrographs of uranyl acetate-stained native and recombinant VLPs of AmCPV. (A) Native AmCPV particles; (B) Recombinant VLPs expressing AmCPV S3 encoded protein; (C) Recombinant VLPs expressing AmCPV S1 and AmCPV S3 encoded proteins. Upper panel (A-1, B-1 and C-1) shows the purified particles in 20 mM PBS, pH 7.3 and lower panel (A-2, B-2, and C-2) shows immunogold staining of these particles. Bar, 20 nm.",
"metadata": {}
},
{
"id": 155,
"image": "PMC2825517_F2_57576.jpg",
"report": "Inguinal lymph node biopsy: histology characteristic of MCD: (A) Haematoxylin & Eosin stained section of lymph node (original magnification × 2.5) showing effaced architecture with few residual follicles. (B) infiltration with large blastic cells (PB, original magnification × 60). (C) Immunostaining reveals blastic cells express HHV-8 (positive cells are brown, original magnification × 60).",
"metadata": {}
},
{
"id": 156,
"image": "PMC1253790_f1-ehp0113-a0182a_3409.jpg",
"report": "Cricket frog swan song? A new examination of historical data shows the decline of cricket frogs in Illinois correlates with organochlorine pesticide use.",
"metadata": {}
},
{
"id": 157,
"image": "PMC2768757_f2_49211.jpg",
"report": "Immunolocalization of toll-like receptors in human corneal, limbal, and conjunctival epithelium. Cryosections of human cornea and conjunctival tissues were incubated with various anti-TLR antibodies and visualized using Alex Fluor 488 conjugated secondary antibodies as described in Methods. Nuclei were stained by DAPI present in the mounting solution. The original pictures were taken at 200X magnification. The insets were taken at 400X magnification.",
"metadata": {}
},
{
"id": 158,
"image": "PMC2945342_F3_74588.jpg",
"report": "Expression of Ngb, Cygb and CA IX in human normal tissues. Tissue microarrays containing cores obtained from various human normal tissues were stained with to antibodies to Ngb, Cygb or CA IX. Positive staining was visualized by the chromogenic reaction of HRP with DAB. Photomicrographs were obtained at 20× magnification, and the scale bar indicates 50 μM. (A) stomach (fundus); (B) small bowel; (C) gallbladder.",
"metadata": {}
},
{
"id": 159,
"image": "PMC2361594_fig3_21503.jpg",
"report": "Immunohistochemical analysis of IFNAR2 expression in HCC tissues. The intensity of IFNAR2 was scored in a scale from 0 to 2; 0 representing no or faint staining (A); 1=moderate staining (B); and 2=strong staining (C). The latter level of staining was used as an inner control (arrow) within the sample, which was designated arbitrarily as intensity 1, because the epithelial cells of the bile ducts generally expressed moderate levels of IFNAR2.",
"metadata": {}
},
{
"id": 160,
"image": "PMC2741052_fig1_45769.jpg",
"report": "Protein kinase C alpha immunohistochemical staining of representative patient tumours. (A, B) Matched primary and recurrent biopsies from patient #10. (C) Primary biopsy from patient #4 exhibiting no disease recurrence. Magnification × 40.",
"metadata": {}
},
{
"id": 161,
"image": "PMC2982821_pntd-0000884-g006_78552.jpg",
"report": "Electron micrographs of S. japonicum male adult worm tegument showing immunogold labelling of SjCytb561 and KLH.Panels A and B were labelled with anti-SjCytb561 sera and show gold probes (examples indicated by arrows) over the apical membrane complex (AMC) of the tegument. Panel C was labelled using anti-KLH sera and does not show labelling in the AMC.",
"metadata": {}
},
{
"id": 162,
"image": "PMC2936088_F0002_73021.jpg",
"report": "(a) Pre-operative maxillary cast, (b) Mock-up preparation done on duplicated cast to assess tooth reduction and create space for new tooth, (c) Preparation completed on tooth nos 11 and 13",
"metadata": {}
},
{
"id": 163,
"image": "PMC1570460_F2_7259.jpg",
"report": "Immunohistochemical staining for neurone-specific enolase (NSE) of a large-cell carcinoma with neuroendocrine morphology (A) and a large-cell neuroendocrine carcinoma (B). (Magnification: 100×, Stain: NSE).",
"metadata": {}
},
{
"id": 164,
"image": "PMC2714311_F2_41954.jpg",
"report": "GFP expression of the transgenic fish in adult Schwann cells. Immunofluorescence staining of adult PNS was performed with a monoclonal antibody to GFP. Adult trunks of wild type (A-C) and transgenic GFP fish (D-F) were sliced horizontally (10 μm). The pictures show bright-field (A, D), fluorescence (B, E), and merged images (C, F). Myelin structures were observed between muscles (white arrow head). Bars: 20 μm.",
"metadata": {}
},
{
"id": 165,
"image": "PMC2919395_pone-0012064-g001_71021.jpg",
"report": "VIGS of Thalictrum dioicum PHYTOENE DESATURASE ortholog TdPDS results in varying degrees of leaf photobleaching.A: Untreated T. dioicum plant. B–F: Distribution of photobleaching in TRV2-TdPDS treated plants. G: Leaflet showing signs of silencing along the vascular tissue. H: Detail of partially photobleached leaflet. I: Typical range of silencing in TRV2-TdPDS treated leaflets. Scale bar = 1 cm.",
"metadata": {}
},
{
"id": 166,
"image": "PMC2796178_pone-0008543-g003_53120.jpg",
"report": "Developmental delay in EpCAM-deficient embryos.(A) Embryonic development in wild type, haplosufficient and EpCAM-deficient littermate embryos (E9.5). Arrows indicate open neural tube. Sagittal sections show EpCAM (βgeo) expression in gut endoderm in EpCAM +/− and EpCAM −/− embryos (arrowheads). The embryos depicted were littermates and photos of whole mounts were taken at identical magnifications. (B) Genotypes of embryos depicted in (A).",
"metadata": {}
},
{
"id": 167,
"image": "PMC3020679_F3_84139.jpg",
"report": "Cellular localization of PvTRAMP as assessed by IFA using hyper-immune anti-PvTRAMP rabbit sera as primary antibody. (A-C) Detection of P. vivax in early schizont stages. (D-I) Parasites in late schizont stage (segmented). The figure shows fluorescence with DAPI and FITC staining, and the merging of both.",
"metadata": {}
},
{
"id": 168,
"image": "PMC2978712_pone-0013947-g004_78370.jpg",
"report": "Tau expression in adult brain biopsy:\n(A) (a–d): immunocytochemistry for 3R tau (green), β-IIItubulin (red) and DAPI (blue) and (B) (e–h) for 4R tau (green), β-IIItubulin (red) and DAPI (blue) in primary culture of biopsy derived human adult neurons. Both isoforms co-localize with β-IIItubulin and are similarly expressed in neuronal cell bodies and axons.",
"metadata": {}
},
{
"id": 169,
"image": "PMC2593002_f11_30869.jpg",
"report": "Visualization of mutations associated with nok m520 gene mutation. Side by side comparison of 72 hours post fertilization embryo eye (A) and heart (B) structures, with nok m520 mutant embryo genotypes on the left, and embryos of the same age without the nok m520 gene mutation. Contrast was enhanced in the retina and heart.",
"metadata": {}
},
{
"id": 170,
"image": "PMC2408922_F1_23548.jpg",
"report": "Morphological examination of LSEC cultures over time by light microscopy. Freshly isolated LSECs cultures were established on 24 well plates and incubated either at hyperoxia (a-c) or at normoxia (d-f). The general morphology of the cultures was monitored by light microscopy at day 1 (a, d), day 3 (b, d) and day 5 (c, f) after isolation. Decline of LSECs cultures may be observed in dishes maintained at atmospheric oxygen levels (a-c) after several days of culture.",
"metadata": {}
},
{
"id": 171,
"image": "PMC2429980_f4_24351.jpg",
"report": "Hyperplasia histology analysis of the spleen in a transgenic mouse compared to a wild type mouse. Shown is a hematoxylin-eosin coloration of spleen taken from an eight-month-old wild type (A) mouse and an eight-month-old transgenic (B) mouse. Hyperplasia of the folliculi in the transgenic mice can be seen in (B). Both pictures were taken at 100X magnification.",
"metadata": {}
},
{
"id": 172,
"image": "PMC2908739_d32e579_69615.jpg",
"report": "Still images from movies of time-course of Rab membrane targeting following mevastatin prenylation block. HeLa cells expressing EGFP-Rab5a (A) or EGFP-Rab1a (B) in the presence of mevastatin were washed with mevastatin-free medium and images collected at the indicated times (in minutes) following removal of the inhibitor. Images shown in A and B correspond to movies 1 and 2, respectively. Bars = 10 μm.",
"metadata": {}
},
{
"id": 173,
"image": "PMC3050856_F3_89348.jpg",
"report": "Immunohistochemical staining for MMP3 (3A), p16 (3B) and UBE2C (3C) in invasive cancers (Magnification × 200).",
"metadata": {}
},
{
"id": 174,
"image": "PMC2724547_F4_43253.jpg",
"report": "The differences in the crypt length and crypt cell content are more obvious between WT and KO animals after the treatment by azoxymethane. After the treatment by azoxymethane, the CyCAP-/- mice develop more extensive mucosal hyperplasia of the colon than WT animals (p < 0.0001, T-test). The mononuclear inflammatory content in the lamina propria is not increased compared to WT animals (20 × magnification, H&E).",
"metadata": {}
},
{
"id": 175,
"image": "PMC2686681_F5_39099.jpg",
"report": "Microphotos of SKOV3 cells under TEM observation. 5A: Abundant mitochondria and nucleoli with increased karyoplasm ratio in non-exposure cells. (TEM × 3500). 5B: In response to SPEF exposure (1 kHz), SKOV3 plasma membrane and karyotheca was disintegrated, subcellular organelles such as mitochondria, endoplasmic reticulum and nucleus were cavitated and swollen. (TEM × 3500). 5C: Typical characteristic of apoptosis was further induced by SPEF exposure (5 kHz). (TEM × 10000).",
"metadata": {}
},
{
"id": 176,
"image": "PMC3059211_pone-0017585-g005_90329.jpg",
"report": "Scanning electron micrograph of actively growing (Panel A) and nonculturable (Panel B) Y. pestis.The coccoid shape of the cells in the tap water microcosm is apparent (Panel B arrows). Magnification in panel A is 5,000X and 10,000X in panel B, bar equal to 1.0 micron.",
"metadata": {}
},
{
"id": 177,
"image": "PMC3042919_F2_87837.jpg",
"report": "Oct-4 expression in bovine blastocysts. Oct-4 immunostaining of blastocysts cultured with 100 ng/ml of either BMP4 or Noggin, Controls were cultured without supplementation. Confocal microscopy, augmentation: 20X and zoom: 2. a) Oct-4 positive cells (green); b) Total nuclei (red); c) Oct-4 positive cells and total nuclei (merged).",
"metadata": {}
},
{
"id": 178,
"image": "PMC3036732_pone-0016985-g002_86717.jpg",
"report": "FITC-PSA staining of human spermatozoa in different treatment groups.A–C: spermatozoa were separated and stained immediately. D–F: spermatozoa were incubated with anti-VDAC2 antibody. G–I: spermatozoa were incubated with normal mouse IgG. J–L: spermatozoa were incubated without any antibody. A, D, G and J: phase-contrast images; B, E, H and K: immunofluorescent images; C, F, I and L: merged images. Magnification was ×1000.",
"metadata": {}
},
{
"id": 179,
"image": "PMC2989755_fig1_79361.jpg",
"report": "Renal biopsy showing Microangiopathic glomerulonephritis.",
"metadata": {}
},
{
"id": 180,
"image": "PMC2854751_f1-ehp-118-a173a_61962.jpg",
"report": "This fluorescence micrograph of differentiated neural progenitor cells shows neurons in green, glial cells in red, and cell nuclei in deep blue (the turquoise results from the overlay of the blue and green channels).",
"metadata": {}
},
{
"id": 181,
"image": "PMC2708163_F2_41403.jpg",
"report": "Phenotypic analyses of AtLIG1 deficient plants. A) Comparison of wild-type and atlig1-RNAiA lines. B) WT and atlig1-RNAi plants photographed 6 weeks after germination. Adaxial leaf from WT (C) and atlig1-RNAi lines (D) Abaxial surface of WT (E) and atlig1-RNAi lines (F). Bar = 1 cm",
"metadata": {}
},
{
"id": 182,
"image": "PMC2821396_F1_56624.jpg",
"report": "Lung biopsy (fine needle biopsy), periodic acid Schiff stain ×400 magnification.",
"metadata": {}
},
{
"id": 183,
"image": "PMC2799220_pone-0008587-g005_53542.jpg",
"report": "Localization of OX1R in the pancreatic islets of Wistar rats with acute, short- and long-term diabetes mellitus.Light micrographs showing OX1R-immunoreactive cells in the pancreatic islet of Wistar 12 h (a); 24 h (b); 8 months (c) and 15 months (d) after the onset of diabetes. Note the large number of islet cells containing OX1R in long-term diabetes (c) and (d). Magnification: ×200.",
"metadata": {}
},
{
"id": 184,
"image": "PMC2935374_pone-0012606-g005_72962.jpg",
"report": "Rac GTPase Activation is Critical for Enhanced Oxidative Damage in the Hippocampus CA1 Following GCI.DAB staining of representative coronal CA1 sections show NSC23766 ability to attenuate staining for oxidative stress markers for lipid peroxidation (4-HNE), DNA damage (8-OHdG) and histone phosphorylation (p-H2A.X). (Four to five animals per treatment group, magnification used was 20X).",
"metadata": {}
},
{
"id": 185,
"image": "PMC2720219_fig2_42698.jpg",
"report": "Representative immunohistochemical staining for SAA on NEC paraffin-embedded specimen (A, × 200), USPC-ARK-1 and USPC-ARK-2 (B and C, × 400), and a liver biopsy (D, × 100). NEC 1 showed negative staining for SAA whereas prominent cytoplasmic staining was detectable in representative tissue blocks from both USPC. Strong cytoplasmic SAA positivity was evident in the positive control (i.e., liver).",
"metadata": {}
},
{
"id": 186,
"image": "PMC2823231_F0001_57052.jpg",
"report": "Biopsy from distal radial fracture 19 days after injury. An old, partly necrotic trabecula and woven bone forming without cartilage precursor within the marrow space.",
"metadata": {}
},
{
"id": 187,
"image": "PMC1310526_F10_4093.jpg",
"report": "Immunoblotting of human granulocyte extracts with various HP1 antibodies. Samples: F, normal female; M, normal male; H, HeLa. Panels: a, monoclonal anti-HP1 α (Upstate); b, monoclonal anti-HP1 β (Chemicon); c, rabbit anti-HP1 β (Upstate); d, monoclonal anti-HP1 γ (Chemicon). Note the trace reaction of anti-HP1 γ with the granulocyte extract (panel d).",
"metadata": {}
},
{
"id": 188,
"image": "PMC3046445_F1_88626.jpg",
"report": "Representative immunohistochemical statinings of ER, PR, HER2, HER4, and cystatin M in DCIS and IBC lesions. The positive (upper row) and negative (lower row) immunostainings for cystatin M, ER, PR, HER2, and HER4 are shown in DCISs and IBCs. Most cells in the upper row of DCIS and IBC lesions show strong nuclear reactivity for ER and PR, strong membrane reactivity for HER2, and strong cytoplasmic staining for HER4 and cystatin M. Magnification × 400.",
"metadata": {}
},
{
"id": 189,
"image": "PMC2822170_F0005_56764.jpg",
"report": "Amyloid appears as pink material deposited between adipocytes (Congo red stain, original magnification × 400).",
"metadata": {}
},
{
"id": 190,
"image": "PMC2995788_F2_80251.jpg",
"report": "Histological findings of prostate cancer. A, The tumor was composed of a poorly differentiated Gleason 4/5 adenocarcinoma (lower left of photograph) and an undifferentiated sarcomatoid carcinoma (upper right of photograph). B, The intraprostatic tumor showing a mixture of cribriform structures and necrosis. C, The tumor in the area of posterior invasion. Arrows indicate multinucleated giant cells. D, Cytokeratin AE1/3 immunostaining of the sarcomatoid carcinoma component.",
"metadata": {}
},
{
"id": 191,
"image": "PMC2894832_F3_67910.jpg",
"report": "Detection of HIV-specific IFN-γ and IL-2 spot forming cells in HIV-infected individuals with continuously detectable HIV replication. Four PBMC samples taken from a representative HIV-infected individual with continuously detectable HIV replication on dates shown on top of the figure together with concurrent log10 copies HIV RNA/ml plasma were tested as described in figure 1.",
"metadata": {}
},
{
"id": 192,
"image": "PMC3065449_F4_91203.jpg",
"report": "Isomin in vitro reassembly. (a) Negative staining of in vitro-reassembled isomin filament. Bar = 200 nm. The inset shows at a greater magnification two loosely packed filaments, revealing thinner protofilaments (arrowheads); bar = 100 nm. (b) Electrophoretic analysis on a 12% SDS-polyacrylamide gel of the sedimented (P) and supernatant (S) fraction after centrifugation of in-vitro reassembled isomin filaments. Migration of molecular weight reference proteins is indicated on the right.",
"metadata": {}
},
{
"id": 193,
"image": "PMC1891001_fig01_11527.jpg",
"report": "Immunohistochemical reactivity for CD31 in human hepatocellular carcinoma (HCC). Note in (A) focal reactivity of a few sinusoids in normal liver; in (B) a moderate increase in cirrhotic liver and in (C) strong immunoreactivity in a poorly differentiated HCC.",
"metadata": {}
},
{
"id": 194,
"image": "PMC2409956_fig2_23850.jpg",
"report": "Morphological effects of khat in HL60 cells. HL-60 cells in early logarithmic growth phase were exposed to an organic extract of khat (200 μg ml−1) for 8 h (panels B and D) or left nonsupplemented (control treated with DMSO solvent) (panels A and C). The cellular morphology was visualised by electron microscopy at × 1000 magnification (panels A–B) and at × 6000 magnification (panels C, D).",
"metadata": {}
},
{
"id": 195,
"image": "PMC2908622_ppat-1001016-g001_69595.jpg",
"report": "RABV infection of APCs, but not fibroblasts, induces type I IFN production.BSR, NA, Raw264.7, or JAWSII cells were infected with RABV (A) or UV-deactivated RABV (B) and the supernatant from the infected cells was UV-deactivated. Reporter cells were pre-treated with the UV-deactivated supernatant (diluted 1∶10) for 24h and then infected with VSV-GFP for 5h. Fluorescence indicates viral replication, and thus, lack of type I IFN. Photos are representative of two independent experiments.",
"metadata": {}
},
{
"id": 196,
"image": "PMC2913979_F1_70442.jpg",
"report": "Primitive neuroectodermal tumor areas showing diffuse sheets of cells at (A) hematoxylin and eosin staining at ×100 magnification, (B) hematoxylin and eosin staining at ×400 magnification. (C) Fibrillary nodules (hematoxylin and eosin staining, at ×40 magnification). And (D) perivascular rosettes (hematoxylin and eosin staining, ×100 magnification) are also shown.",
"metadata": {}
},
{
"id": 197,
"image": "PMC2667670_pone-0005295-g001_37138.jpg",
"report": "Qualitative FRAP experiments of red alga P. cruentum WT cell.A, selected fluorescence images from typical sequences recorded before bleaching, immediately after bleaching of PBsomes, and at various time lapses. Excitation is at 568 nm and detection range is from 650 to 750 nm. Scale bar: 5 µm; B, total fluorescence intensity of bleached cell region as a function of time. The recovery of the fluorescence is presented as square spots and fitted to an exponential function (solid line).",
"metadata": {}
},
{
"id": 198,
"image": "PMC2241821_F4_17545.jpg",
"report": "Expression of randomly picked scFvs in HeLa cells. Cells were transfected with scFv-EGFP constructs as indicated. 13R4 and 1F4 represent the positive and negative controls, respectively [5]. At 24 h post-transfection, cells were fixed and visualized under a fluorescent microscope with the fluorescein isothiocyanate filter set. The micrographs represent typical fields containing a similar number of cells in each case. Magnification: × 400.",
"metadata": {}
},
{
"id": 199,
"image": "PMC2901306_F5_68436.jpg",
"report": "Elemental analysis of intracellular QDs. Figure A shows an intracellular vesicle containing QDs and the area analyzed by ESI as shown at higher magnification in figure B. Elemental analysis by ESI for S (E), Cd (F) and Os (G) has been performed. Figure C further represents the ESI signal extraction of S and Se. Figure D represents the Se signal without the Os signal. Scale bar A equates to 200 nm and B-G equate to 50 nm.",
"metadata": {}
},
{
"id": 200,
"image": "PMC2879277_F3_65332.jpg",
"report": "Curcumin ameliorates αS-induced morphological changes in SH-SY5Y cells evaluated by fluorescence microscopy. After 48 hr incubation, cells were fixed with 4% paraformaldehyde, stained with Hoechst 33342 (5 mg/mL) and analyzed using a Nikon TE300 fluorescence microscope. Fluorescence micrographs (100× magnification) of the (A) control cells, (B) cells exposed to αS, (C) cells exposed to αS+curcumin and (D) curcumin.",
"metadata": {}
},
{
"id": 201,
"image": "PMC1388236_F1_4720.jpg",
"report": "Endothelial microstructure. Rat mesenteric artery incubated with vehicle (DMSO 0.4 ml/L, A, B and C) or DSP (0.4 ml/L, E, F and G) for 24 hrs. Human MCA incubated with vehicle (DMSO 0.8 ml/L, D) or DSP (0.8 ml/l, H) for 12 hrs. Magnification: × 3000 for A and E; × 5000 for B, F, D and H; × 10000 for C and G. EC = endothelial cells; SMC = smooth muscle cells; EM = elastic membrane.",
"metadata": {}
},
{
"id": 202,
"image": "PMC2839984_F2_59333.jpg",
"report": "Microscopic findings of bladder biopsy specimens revealed histological changes associated with hemorrhagic cystitis (× 10).",
"metadata": {}
},
{
"id": 203,
"image": "PMC2898770_F3_68234.jpg",
"report": "3D view of the locked targets. 3D representation of the HIV-1 homodimer (1HSG) protease. Same colour codes as Figures 1 and 2. a: SGI flap (4 orange SLs + 3 green invariants) b: SGI flap + SGI canti (2 red SLs + 1 green invariant) c: SGI fulc (2 yellow SLs + 1 green invariant) d: SGI fulc + SGI canti (4 yellow SLs + 1 green invariant) The 3D molecules were built by pymol software.",
"metadata": {}
},
{
"id": 204,
"image": "PMC3066639_fig4_91383.jpg",
"report": "Electron micrographs of E-LDL-bound C1q molecules. (a, b) Examples of C1q molecules interacting through most of their globular domains (a) or only a few (b). (c) Representative example of a free C1q molecule (modified from [15], with permission).",
"metadata": {}
},
{
"id": 205,
"image": "PMC2707626_pone-0006303-g007_41314.jpg",
"report": "Cultured Symbiodinium motile cells viewed with differential interference contrast (DIC) microscope without the DIC analyzer.(a) CS-156. (b) FKM0207. Bright areas near the sulcus (arrows) indicate that strong light reflection and polarization may occur in this area corresponding to the location of the clusters as revealed by transmission electron microscopy.",
"metadata": {}
},
{
"id": 206,
"image": "PMC2637293_F1_33969.jpg",
"report": "Photomicrograph of bone marrow trephine biopsy (case 1) shows hypocellular marrow spaces with 70% of fat cells. There are reduced numbers of hematopoietic cells with increased numbers of blasts (a, b). One of the focuses shows an area of bone marrow necrosis punctuated by hyperchromatic blasts and histiocytes (c, d). Hematoxylin and eosin stain, a ×40; b ×400; c ×40; d ×400.",
"metadata": {}
},
{
"id": 207,
"image": "PMC2997091_F1_80484.jpg",
"report": "Hematoxylin and Eosin staining. Examples of hematoxylin and eosin (H&E) staining of healthy tissues (A), ulcerative colitis (B), adenomas (C) and adenocarcinomas (D) (magnification ×100).",
"metadata": {}
},
{
"id": 208,
"image": "PMC1877879_pgen-0030083-g004_11167.jpg",
"report": "DAPI Staining of Atzip4-1 PMCs during Meiosis(A) Leptotene, (B) zygotene: The synapsed portion of (B) has been magnified and is presented in the boxed area of the figure. (C) Pachytene, (D) diakinesis, (E–H) metaphase I, (I) anaphase I, (J) metaphase II, (K) anaphase II, (L) end of meiosis.Bar, 10 μm.",
"metadata": {}
},
{
"id": 209,
"image": "PMC546200_F1_1169.jpg",
"report": "Scanning electron micrograph survey of pumice granules and biofilm development. Before colonisation (A) pumice granules are blank. After 6 month of operation (B), rod shaped cells cover the pumice surface. In the 12 month biofilm, an abundant exopolymeric matrix is visible on pumice granules both at the bottom (C) and top (D) of the column.",
"metadata": {}
},
{
"id": 210,
"image": "PMC1847803_F5_10290.jpg",
"report": "Early expression of cxcr4b. A: expression is first detected in a cluster of placodal cells (arrow) in 19 hpf embryos. B: expression is much enhanced in 20 hpf embryos. C: by 22 hpf the primordium has made contact with the SDF1 trail and elongates into somite 1. D: at about the same time cxcr4 expression is down-regulated in a small cluster of cells near the presumptive trailing edge of the primordium (arrow).",
"metadata": {}
},
{
"id": 211,
"image": "PMC2442062_F4_24937.jpg",
"report": "CORT-induced nuclear translocation of NFAT2 in mLTC-1 cells. mLTC-1 cells were transiently transfected with NFAT2-GFP expressing vector. 36 h after transfection, cells were treated with 100 nM CORT or 100 nM CORT plus 100 ng/ml CsA for 12 h. The cells were rinsed with PBS and fixed. Representative fields of cells were viewed by Confocal microscopy and photographed.",
"metadata": {}
},
{
"id": 212,
"image": "PMC2374951_F5_22155.jpg",
"report": "Tumor formation and lung metastases 30 days after tumor implantation. (a) Primary tumor weights. (b) The average numbers of lung metastatic nodules. (c) Representative photos of the lungs. The arrows point to the metastatic nodules in lung. (d) Representative hematoxylin and eosin staining sections of the lungs were photographed at 40× magnification. *P < 0.05. M, metastatic nodule; N, normal.",
"metadata": {}
},
{
"id": 213,
"image": "PMC2803811_F2_54120.jpg",
"report": "Photomicrograph shows granulomatous inflammation, hematoxylin and eosin, 400× (a); higher magnification shows an epithelioid cell granuloma with chronic inflammation, hematoxylin and eosin, 600× (b).",
"metadata": {}
},
{
"id": 214,
"image": "PMC2806049_F4_54785.jpg",
"report": "Immunohistochemical detection of TIA-1 across tissue types and age groups. Representative\n TIA-1 signals in photomicrographs taken from the indicated tissue sections\n from human tissue arrays. Images are shown at ×200 magnification.\n \n ",
"metadata": {}
},
{
"id": 215,
"image": "PMC2837148_fig6_58869.jpg",
"report": "Electron microscopic analysis of Candida albicans interaction with LCs. (A) Electron microscopic picture of LCs which has internalized C. albicans (C). Arrow is directed towards C. albicans. (B–D) Gold labelling of Langerin demonstrates Langerin localization at the binding site of LCs and C. albicans. Arrows are directed towards Langerin gold labelling. Picture (B) is a magnification of (A), and (D) is a magnification of (C).",
"metadata": {}
},
{
"id": 216,
"image": "PMC2851658_ppat-1000849-g002_61550.jpg",
"report": "Histopathology of rMA15 virus infected mouse strains.Mice were sacrificed at days 2, 5 and 9 post-infection for histopathological analysis. Lung sections were stained with H&E and photomicrographs of individual airways are shown in the figure. The left side of each matched pair is a 10X picture and the right side is 40X.",
"metadata": {}
},
{
"id": 217,
"image": "PMC2978702_pone-0013906-g002_78281.jpg",
"report": "PET blots of cerebellum.PET blots show prominent deposition of PrPSc in granular and molecular cell layers in clinically diseased vCJD and BSE inoculated animals whereas the subclinical vCJD inoculated primate only shows faint PrPSc in granular and molecular cell layers (scale bar in lower left image 1 mm).",
"metadata": {}
},
{
"id": 218,
"image": "PMC2374879_pone-0002142-g003_22124.jpg",
"report": "Expression and localization of Wnt3a in lung tissues of donor and IPF patients.Immunohistochemical staining was performed on tissue sections of donor (a) or IPF lungs (b). Representative pictures with focus on the bronchial (upper panel) or alveolar epithelium (lower panel) are given. Stainings are representative of two independent experiments using at least three different donor or IPF lung tissues (magnification as indicated).",
"metadata": {}
},
{
"id": 219,
"image": "PMC2747840_F5_46604.jpg",
"report": "Transduction of sensory fibers within the dorsal horn following rAAV2/6 delivery via different routes. (A) eGFP expression in dorsal horn following sciatic nerve, subcutaneous, intramuscular, and intrathecal injection of 2.6 × 105 tu rAAV2/6. Scale bar: 100 μm. Confocal microscope images for CGRP (red, lamina I and II outer) and IB4 (blue, lamina II inner) against eGFP expression (green) in the dorsal horn following sciatic nerve (B) and intrathecal (C) injection. Scale bar: 50 μm.",
"metadata": {}
},
{
"id": 220,
"image": "PMC2685374_F2_38877.jpg",
"report": "Tumor promoters induce rapid disassembly of epithelial tight junctions and adherens junctions. Confluent HPAF-II cell monolayers were treated for 5 h with either vehicle, OI-V, or TPA (each, 1 μM). Localization of AJ proteins (E-cadherin, β-catenin) and TJ proteins (occludin, ZO-1) was determined by fluorescence labeling and confocal microscopy. Both tumor promoters induce translocation of AJ and TJ proteins from the areas of cell-cell contact into cytosol (arrows). Bar, 20 μm.",
"metadata": {}
},
{
"id": 221,
"image": "PMC2698670_F12_40297.jpg",
"report": "Allergan Biocell in scanning electron microscopy at 3330× magnification with a 5-µm scale bar. This image shows the base of a Biocell depression at high magnification and shows that this surface has a secondary, finer wavy topography to its internal surface.",
"metadata": {}
},
{
"id": 222,
"image": "PMC2769422_fig-001_49466.jpg",
"report": "Macroscopic and microscopic findings of the cystic hygroma. (A) a huge nuchal cystic mass measuring 20 × 15 mm is observed around the neck (arrows). Externally, no other apparent malformations are noted. (B) Histopathological examination revealed numerous dilated lymphatics with proliferation of spindle-shaped mesenchymal cells and edema in the subcutaneous area (HE, ×200).",
"metadata": {}
},
{
"id": 223,
"image": "PMC2860995_pone-0010384-g002_63052.jpg",
"report": "Immunostaining for Ab-HepIII in the infarct region.Hearts from rats sacrificed on 1 day after injection. The rats were injected intravenously with either (a) PBS or (b) the Ab-HepIII 1 day post-MI. The presence of the Ab is indicated by the brown stain. For the sake of clarity, we have outlined the infarct region. At high magnification, we were also able to see fluorescence within the infarct region(c), as indicated by the arrow, of the FITC-labeled peptides (indicated in black).",
"metadata": {}
},
{
"id": 224,
"image": "PMC2796396_pcbi-1000638-g005_53149.jpg",
"report": "Path density and path curvature are two independent measures.A. The path plot of a mouse-session portrays a circular bundle of paths. B. The contour plot of the same circular bundle of paths does not pick up the high path density patches because path curvature is of a different scale. Curvature window size and colors are as in Figure 3.",
"metadata": {}
},
{
"id": 225,
"image": "PMC2206006_F1_16283.jpg",
"report": "Expression of ETARs and ETBRs in rat dorsal root ganglion. Sections of lumbar rat dorsal root ganglion were analysed for the expression of ETARs (A) or ETBRs (B, C) using affinity-purified antibodies. For the identification of TRPV1-postive neurons co-staining with a TRPV1 antibody (A, B) was performed. Expression of ETBRs in glial cells was demonstrated by co-staining of the S100 antigen (C). Bars: 20 μm.",
"metadata": {}
},
{
"id": 226,
"image": "PMC2660713_F1_36567.jpg",
"report": "A 36-year-old HIV-infected woman with Mycobacterium avium disease. A) Photograph of skin lesions on right leg, taken before treatment. B) Histopathologic appearance of skin biopsy specimen from right leg lesion (stain, hematoxylin and eosin; magnification ×40).",
"metadata": {}
},
{
"id": 227,
"image": "PMC1208912_F3_3134.jpg",
"report": "Confocal immunofluorescence for aquaporins and solute transporters in WIF-B cells. WIF-B cells were fixed, permeabilized, and labeled with anti-AQPs, AE2, Mrp2 or Bsep. Fluorescence localization was viewed by laser scanning confocal microscopy (see \"Materials and Methods\" for details). *, bile canaliculi structures.",
"metadata": {}
},
{
"id": 228,
"image": "PMC2777864_F7_50906.jpg",
"report": "Co-localization between PTEN and BMI1 in primary prostate cancer tissues. Double IF staining for BMI1 (red) and PTEN (green) in normal prostatic gland (normal), PIN, PTEN-negative carcinoma, and PTEN-positive carcinoma. Nuclei were counter-stained with DAPI (blue). Images were captured with a confocal microscope. Scale bar represents 20 μM.",
"metadata": {}
},
{
"id": 229,
"image": "PMC1872031_F8_10971.jpg",
"report": "1. Photograph of a patient showing swelling over left shoulder: later diagnosed as Hemangiopericytoma. 2. X-ray showing lesion involving the left clavicle. 3. Smear showing malignant round cells radiating from vessels. [MGG ×400]. 4. Histological section of the same case showing monomorphic round cells radiating from cells [H&E × 200].",
"metadata": {}
},
{
"id": 230,
"image": "PMC3062588_F1_90792.jpg",
"report": "HE staining of paraffin-embedded sections. A: Uterus of 140 ± 5 d ICR mice as control. B:Uterus of 90 ± 5 d ICR mice with biopsy confirmed adenomyosis; C: Uterus of 140 ± 5 d ICR mice with biopsy confirmed adenomyosis; D: Uterus of 190 ± 5 d ICR mice with biopsy confirmed adenomyosis; E: Uterus of 240 ± 5 d ICR mice with biopsy confirmed adenomyosis; (L, luminal epithelium; G, glandular epithelium; S, stromal cell; M, myometrium cell; arrows, ectopic endometrium; Bar = 50μm).",
"metadata": {}
},
{
"id": 231,
"image": "PMC2717979_F2_42475.jpg",
"report": "ST rapidly reduces focal contact size in PMC42-LA cells. Cells were treated for 3 h with 10 ng/ml EGF, 40 nM ST or both, fixed and immunostained for the focal contact specific protein paxillin (b+w, green in enlarged images) and F-actin (red). Magnification: ×63, scale bar = 10 μM.",
"metadata": {}
},
{
"id": 232,
"image": "PMC2930302_F0003_72322.jpg",
"report": "Photomicrograph showing polyhedral cells arranged singly and in loose aggregates possessing a moderate amount of cytoplasm containing brown pigment (Papanicolaou stain, ×400)",
"metadata": {}
},
{
"id": 233,
"image": "PMC1913502_F6_12133.jpg",
"report": "CAR expression in human tissue. Expression of the coxsackie adenovirus receptor (CAR) in biopsies of normal human colon (upper panel) and human colon cancer (lower panel). Red staining of CAR after reaction with a monoclonal anti-CAR antibody and an APAAP detection system.",
"metadata": {}
},
{
"id": 234,
"image": "PMC2129121_pone-0001338-g003_15322.jpg",
"report": "Lin- cKit+Flk-1+ BM cells have endothelial properties.A) Schematic representation of the experimental procedure. B) Immunofluorescence on matrigel sections showing the incorporation of GFP+ Lin- c-kit+ Flk-1+ cells into vessels (arrowheads). Yellow and orange insets show magnification of GFP+ cells. Green: GFP; Red: VE-Cadherin; Blue: DAPI. Scale bar 50 µm.",
"metadata": {}
},
{
"id": 235,
"image": "PMC2662459_f3-ijms-10-00037_36765.jpg",
"report": "Images of midbrain micromass cultures, exposed for 5 days to different concentrations of OTA. Neurospheres were stained with haematoxylin (16 × magnification). After exposure to 2.5 μg/mL neurospheres were smaller and more numerous, after two highest concentrations no differentiated cells were observed.",
"metadata": {}
},
{
"id": 236,
"image": "PMC2607279_F2_31774.jpg",
"report": "Equine oocytes incubated with GalTase and with anti-GalTase antibodies (A) or preimmune serum (B); equine oocytes incubated without GalTase and with anti-GalTase antibodies (C) or preimmune serum (D). (Observation with an epifluorescent microscope at 400 × magnification).",
"metadata": {}
},
{
"id": 237,
"image": "PMC2654538_pone-0004870-g005_35933.jpg",
"report": "Paraformaldhyde fixation of fluoromycobacteriophage-infected mycobacteria.\nM. smegmatis mc2155 cells were infected with phAE87::hsp60-EGFP and fluorescence detected in A, live cells, B, fixed cells and C, fixed cells after 2 weeks at 4°C. Top, fluorescence micrograph images; bottom, merge of fluorescence and phase contrast images. Scale bar, 10 µm.",
"metadata": {}
},
{
"id": 238,
"image": "PMC2761003_fig04_47875.jpg",
"report": "Fluorescence in situ hybridization (FISH) confocal microscope photographs of Robbea sp.1 (A–D), Robbea sp.2 (E–H) and Robbea sp.3 (I–L) symbionts attached to the worm surface. Each single symbiont is triple stained with a eubacteria-specific probe (green), a Gammaproteobacteria-specific probe (blue), and a symbiont-specific probe (red). (D), (H) and (L) are overlay pictures of (A)–(C), (E)–(G) and (I)–(K), respectively. Scale bar is 2 µm.",
"metadata": {}
},
{
"id": 239,
"image": "PMC2361288_fig1_21398.jpg",
"report": "Histological section stained with anit-Ki67, 1 : 6000. Pretreatment Tris-EDTA pH7.6 (magnification × 200).",
"metadata": {}
},
{
"id": 240,
"image": "PMC3022558_F5_84476.jpg",
"report": "Dilution trial of agroinoculant with FECT and p19 on N. benthamiana plants. Top row: FECT40/GFP vector. Bottom row: JL24/GFP vector. A.t. cell suspensions were diluted, as noted in the figure, from an initial OD600 of 1.0. Pictures were taken under UV illumination at 4 dpi with photos taken at same exposure.",
"metadata": {}
},
{
"id": 241,
"image": "PMC2904739_F2_68832.jpg",
"report": "Gross examination of lesion. On macroscopical examination, the lesion was composed of grayish smaller tissue fragments of variable sizes and a whitish ovoid mass, measuring 3.0 cm in diameter. No necrosis, haemorrhage and gross calcification were found in the mass and other tissue fragments.",
"metadata": {}
},
{
"id": 242,
"image": "PMC2921398_F2_71273.jpg",
"report": "Histological assessment of EMPD. (A) H&E staining indicated Paget cells into the epidermis (original magnification × 100), and (B) The dermis contained a poorly differentiated adenocarcinoma (original magnification × 200).",
"metadata": {}
},
{
"id": 243,
"image": "PMC2775945_pone-0007913-g002_50482.jpg",
"report": "Lysosome ultrastructure appears unaltered during Nlrp1b-mediated pyroptosis.(A) RAW 264.7 cells were pre-stained with Lysotracker Red DND-99 followed by LT or untreated (NT) for 75 min and imaged on glass slides at 40× magnification. Black arrows correspond to condensed nuclear DNA observed in pyroptotic cells.",
"metadata": {}
},
{
"id": 244,
"image": "PMC1832177_F3_10172.jpg",
"report": "TUNEL staining of Spiroplasma infected male embryo (A) and female embryo (B), both at stage 10, 5–7 h AEL. Red fluorescence indicates apoptotic nuclei; whilst the female embryo shows the characteristic pattern of apoptotic nuclei restricted to the cephalic furrow, apoptotic nuclei are observed throughout the male.",
"metadata": {}
},
{
"id": 245,
"image": "PMC2952964_F4_75633.jpg",
"report": "miR-449a triggers cellular senescence in DU-1.1 and B5 cellsDU-1.1 and B5 cells were transfected with mock, miR-Con, or miR-449a for 72 hours. Transfection of miR-449a at 10 or 25 nM concentrations improved cell density for analysis. Cells were fixed in formaldehyde and stained for SA-β-gal activity overnight. Images were captured by phase contrast microscopy at 200X magnification. Dark perinuclear staining marks senescent cells.",
"metadata": {}
},
{
"id": 246,
"image": "PMC2758850_F6_47491.jpg",
"report": "Tertiary structure of E. coli EF-Tu (PDB ID: 1EFC) [57], which has two identical polymer chains (A and B). The covarion residues are mapped on the A chain (the top polymer). The red arrow points to the purple strip of a loop region of 10 nearly consecutive covarion sites (sites 37, 38, 40 - 46, 48 in 1EFC), which corresponds to sites 31, 32, 34 - 40, 42 on the EF alignment listed in Figure 5. The loop region is connected to the two helices, one at either end.",
"metadata": {}
},
{
"id": 247,
"image": "PMC2984396_F6_78663.jpg",
"report": "Morphology of differentiated osteoclast cells. May Grunwald-Giemsa staining of (A) multinucleated osteoclasts and (B) MC3T3-E1 cells. Both cells were subjected to cytospin at day 3, 5, 7 or 10 differentiations prior to May Grunwald-Giemsa staining. The figure shows that the numbers of multinucleated osteoclast cells increased upon differentiation of mononucleated cells but not MC3T3-E1 cells. The black arrows show the multinucleated osteoclasts (400× magnification).",
"metadata": {}
},
{
"id": 248,
"image": "PMC1563456_F6_7056.jpg",
"report": "Our procedure allows automated production of a map that identifies locations of interest in an electron micrograph, illustrated here for the C test function. Instead of simply counting and comparing structures in an unprocessed image, the virologist is aided considerably in this task by the availability of such a map. The various structures are sorted left to right in order of descending matching values beginning at the left side of the top row.",
"metadata": {}
},
{
"id": 249,
"image": "PMC2994737_f5_80024.jpg",
"report": "Immunofluorescence imaging of receptors on HCE cell membrane. Images shown were taken using the FITC filter of confocal microscope (Leica SP20). Cells were blocked for 90 min, washed, and then either mock treated with buffer alone (B, D, F) or treated with primary antibodies for Nectin-1 (A), HVEM (C), and PILR-alpha (E). Images were taken after the incubation of HCE cells with FITC-conjugated secondary antibodies. Staining of cells with green demonstrate receptor expression.",
"metadata": {}
},
{
"id": 250,
"image": "PMC2923536_F1_71531.jpg",
"report": "B. rapa genotype R-o-18 plant development. A) Seedling three weeks after sowing, B) Fully expanded rosette leaf, C) mature and fully elongated fruit, D) main shoot of flowering R-o-18 plant seven weeks after sowing, E) open flower, F) scanning electron micrograph of the base of gynoecium at anthesis, G) cross section of fully elongated R-o-18 fruit.",
"metadata": {}
},
{
"id": 251,
"image": "PMC1904365_pgen-0030101-g002_11912.jpg",
"report": "LM of the SAM from Paraffin Sections of Maize Seedlings(A) The apex before LM is shown.(B) Laser ablation is used to isolate the SAM from surrounding leaf primordia and stem tissue, without heating or damaging adjacent SAM tissues.(C) SAM tissue is microdissected via laser pressure catapulting, in which the laser is focused beneath the targeted SAM tissue and a high photonic force catapults the tissue into a collection tube suspended above the sample.",
"metadata": {}
},
{
"id": 252,
"image": "PMC1200430_F2_3020.jpg",
"report": "Immunohistochemical staining of ATP-binding cassette proteins in human lung. A. apical expression of P-gp in bronchial epithelium (COPD patient; frozen section, antibody C219), B. basolateral expression of MRP1 in bronchial epithelium (COPD patient; antibody MRPr1), C. MRP1 expression in bronchoalveolar lavage cells (healthy individual; antibody MRPr1). Lu, lumen. Scale bar = 25 μM.",
"metadata": {}
},
{
"id": 253,
"image": "PMC2898085_F6_68176.jpg",
"report": "The effects of Tsc22d3 and Sgk1 knockdown on dendritic spine morphology in cultured primary neurons. Representative micrographs and three-dimensional Imaris reconstructions of dendritic segments of hippocampal and cortical neurons are presented. The neurons were transfected with pSUPER (control) or GILZsh mix or SGK1sh mix in pSUPER on day in vitro 14 for 3 days. GFP was used to highlight transfected cell morphology.",
"metadata": {}
},
{
"id": 254,
"image": "PMC2929556_F0002_72276.jpg",
"report": "Microscopic hair characteristics (cuticle, medulla and cross-section) of Pantholops hodgsonii (left side) and Capra hircus (right side)",
"metadata": {}
},
{
"id": 255,
"image": "PMC2235856_F8_17457.jpg",
"report": "Hydrogel Reversibility. Time resolved confocal scan of 15 μm spheres suspended in situ with pH and enzyme triggered reversing. Color indicates time; red is the start time, green is at 5 minutes, blue is at 10 minutes. Lack of color differentiation indicates limited mobility.",
"metadata": {}
},
{
"id": 256,
"image": "PMC2409630_fig3_23755.jpg",
"report": "Effect of yessotoxin on morphology of MCF-7 cells in culture. Phase contrast microscopy (magnification × 200) of MCF-7 cells after treatment for 4 days with vehicle (A) or 1 nM YTX (B).",
"metadata": {}
},
{
"id": 257,
"image": "PMC2805630_F5_54689.jpg",
"report": "Cytokeratin 8 staining on USSC-derived spheres. A, As a positive control for CK8 expression, primary human bronchial epithelial (16HBE14o-) cells were stained. B, Representative microscopy images of seven day spheres fixed, sectioned and stained with a Cytokeratin 8 (CK8) antibody (Alexa488; green) and counter stained with 4, 6-diamidino-2-phenylindole (DAPI; blue). The respective negative isotype control images are also shown. (Magnification ×200; scale bar is 100 μm.)",
"metadata": {}
},
{
"id": 258,
"image": "PMC2265287_F5_18614.jpg",
"report": "Blocks of archived lung from autopsies of patients dying without a lung disease showed normal staining for ferritin at the airways and among a few alveolar macrophages (left). Positive staining for ferritin was increased in lung tissue of patients diagnosed with PAP (right). Expression of the protein in the patients with PAP appears to include not only airway epithelium and macrophages but also material filling the alveolar spaces. Magnification approximates 200×.",
"metadata": {}
},
{
"id": 259,
"image": "PMC2830486_pone-0009452-g004_58191.jpg",
"report": "Microscopic aspect of RT-associated tonsillar specimen subjected to immunohistochemistry.\nS. aureus-bacteria were marked by the APAAP staining technique. A: base of a tonsillar crypt (x200) B: necrosis (x200) C: tonsillary epithelium (x1000). These photographs demonstrate that RT-associated S. aureus isolates are involved in pathological processes and are not transient colonizers.",
"metadata": {}
},
{
"id": 260,
"image": "PMC2225469_fig1_17108.jpg",
"report": "Two methods to establish the orthotopic tumors. \nPanel (a) shows surgical exposure of the proximal\ntibia plus drilling a hole through cortical bone to accommodate\nosteosarcoma cells (25× magnification); Panel (b) shows a high\nmagnification (200×) of orthotopic bone tumor with the surgical\nmethod. Panels (c) and (d) example the tumor by direct injection of\ntumor cells to proximal tibia, mostly out growth surrounding the\nbone (25× and 200×).",
"metadata": {}
},
{
"id": 261,
"image": "PMC2636757_F2_33845.jpg",
"report": "Confocal microscopy illustration of samples of MCF-7 cells A-C) without treatment; D-F) treated 30 minutes with heparitinase (in figure F a group of three cells), Cells were stained with ErbB4 carboxy-terminus specific HFR-1 antibody. Accumulation of immunoreactive perinuclear granules is indicated by arrows. G) Activity of Heparitinase was controlled by simultaneous Western analysis of ErbB4 cleavage from parallel samples.",
"metadata": {}
},
{
"id": 262,
"image": "PMC2837561_fig1_58974.jpg",
"report": "Microphotographs of ovarian cancer (A), gastric cancer (B), and PAC (C) showing positive nuclear APE1 expression (magnification × 200).",
"metadata": {}
},
{
"id": 263,
"image": "PMC2729294_fig1_43866.jpg",
"report": "(a) Papillary fronds with delicate fibrovascular core (H&E, X20); (b) border of villous adenoma with squamous epithelium in the urethral diverticulum (H&E, X40); (c) columnar epithelium with abundant goblet cells demonstrating nuclear stratification, surface mitotic figures and loss of polarity (H&E, X100); (d) abundant mitosis, including atypical forms (H&E, X400).",
"metadata": {}
},
{
"id": 264,
"image": "PMC2769324_fig-003_49329.jpg",
"report": "40× magnification showing vascular channels lined by endothelial calls showing nuclear atypia and pleomorphism. The surrounding stroma is loose and myxoid.",
"metadata": {}
},
{
"id": 265,
"image": "PMC2390850_pone-0002327-g001_22933.jpg",
"report": "Phase contrast images of NEB-1 keratinocytes undergoing incremental uniaxial strain.Average uniaxial strain is reported in the lower left corner of each panel. Some loss of adhesion occurs at such high strains, which is why cell strain is slightly negative when the rubber substrate is returned to its relaxed state (M). Scale bar = 50 µm.",
"metadata": {}
},
{
"id": 266,
"image": "PMC2710317_F3_41571.jpg",
"report": "Microscopic finding of the tumor (higher magnification). AB: More than 95% of the tumor was adipose component, containing only scant epithelial components. (HE staining, AB: ×400).",
"metadata": {}
},
{
"id": 267,
"image": "PMC2270268_F4_19390.jpg",
"report": "Fluorescence and brightfield images of post-laser manipulated 8-cell stage embryos. Embryos were porated for exogenous FITC delivery using an average laser power of 45 mW. The beam dwell time was set to 50 ms with three pulsing events of the galvo for (a, b) and two for (c, d). Three pores were made in each of 2 blastomere cells, yielding a total of six pores for the entire embryo. Scale bars for (a, b, c, d) represent 200 μm.",
"metadata": {}
},
{
"id": 268,
"image": "PMC3068475_fig5_91466.jpg",
"report": "Adipophilin in cellular membranes. Survey freeze-fracture view of a lipid-laden macrophage immunogold-labeled for adipophilin. Apart from positive labeling in the periphery of lipid droplets prominent label is seen in the P face of the plasma membrane (PL) and ER membranes. The E faces of the ER, mitochondrial and vesicle membranes are devoid of label. Inset: higher magnification of the P face of ER and plasma membrane. M mitochondria. Bar: 0.2 μm.",
"metadata": {}
},
{
"id": 269,
"image": "PMC3071363_pntd-0001011-g003_91807.jpg",
"report": "Immunolocalization of SmAP in adult parasites.A. Cross section through a male/female couple showing widespread immunofluorescent staining with anti-SmAP antibody. B. Higher magnification image of the peripheral tissue of an adult male. The arrow indicates the outer tegument. C. Electron micrograph of the adult tegument showing immunogold labeling of SmAP. Arrows indicate gold particles at the host-parasite interface. Numbers above scale bars represent microns.",
"metadata": {}
},
{
"id": 270,
"image": "PMC3001466_pone-0015130-g014_81030.jpg",
"report": "3-dimensional model of the ascorbate binding region of the adrenergic receptor.The position of the ascorbate binding site (highlighted in blue beneath the arrow) is immediately adjacent to the adrenergic binding site. (Model provided by, and adapted, with permission from Lei Shi and Jonathan A. Javitch, Columbia University College of Physicians and Surgeons, and reprinted from the Annual Review of Pharmacology and Toxicology, volume 42 © Annual Reviews www.annualreviews.org) [22].",
"metadata": {}
},
{
"id": 271,
"image": "PMC1261536_F3_3514.jpg",
"report": "Cryostat sections of bronchial biopsies stained with antibodies against the ln γ1 chain. Allergic asthma (A), non-allergic asthma (B) and healthy control (C) (original magnification ×170). The comparison of the thickness of SEBM is shown and the significant differences between the groups shown in the figure. Mayer's hematoxylin.",
"metadata": {}
},
{
"id": 272,
"image": "PMC2360342_fig7_21184.jpg",
"report": "EBOECs maintain endothelial cell function. Uptake of acetylated LDL is a method for the identification of functional endothelial cells. EBOECs take up acetylated LDL (left) and form vascular tubes in culture (right). Images are representative of triplicate slides (LDL uptake) or wells (vascular tubes).",
"metadata": {}
},
{
"id": 273,
"image": "PMC2754338_pone-0007315-g012_47090.jpg",
"report": "Immunohistochemical staining for adenocarcinoma (Reck, Cdh5, S100A14).(a) Immunohistochemical staining of control lung tissue, (b) lung cancer at 10× magnification and (c) at 40× magnification (d) lung cancer in the presence of primary antibody, after preincubation with blocking peptide and (e) positive control. 7 = reversion-inducing-cysteine-rich protein with kazal motifs (Reck), 8 = cadherine 5 (Cdh5) and 9 = S100 calcium binding protein A14 (S100A14).",
"metadata": {}
},
{
"id": 274,
"image": "PMC2958945_F1_76603.jpg",
"report": "Cases with concordant judgment of HER2 score between CNB and surgically resected specimens. A-B. Case 3: HER2 score for both the CNB specimen (A) and the surgically resected specimen (B) was 3+. C-D. Case 22: HER2 score for both the CNB specimen (C) and the surgically resected specimen (D) was 2+. E-F. Case 2: HER2 score for both the CNB specimen (E) and the surgically resected specimen (F) was 0. Immunoperoxidase reaction, original magnification ×200.",
"metadata": {}
},
{
"id": 275,
"image": "PMC2732489_F3_44363.jpg",
"report": "Adherence patterns of enteropathogenic Escherichia coli (EPEC) strains. Localized adherence (LA), diffuse adherence (DA), aggregative adherence (AA), and localized adherence-like (LAL). Magnification: X100.",
"metadata": {}
},
{
"id": 276,
"image": "PMC3049761_pone-0017475-g001_89091.jpg",
"report": "Uptake of fluorescent dyes by neurons of Heterodera schachtii.\nAfter 16 h exposure to 1 mM of A) FITC B) Alexa Fluor 488 and C) bisbenzimide fluorescence was observed in J2 of H. schachtii using epillumination excitation under standard conditions. Images A) and B) are lateral views and C) a dorsal view. Key: c, cephalic framework; (showing autofluoresence); a, amphidial pouch; d, tract of amphidial dendrites; n, nerve ring; g, region of the lateral and ventral ganglia. Scale bars are 10 µm.",
"metadata": {}
},
{
"id": 277,
"image": "PMC519028_F5_540.jpg",
"report": "Photomicrographic panoramic view of the patient's cutaneous biopsy showing an asymmetric lesion with a basal confluent growth (Hematoxylin and Eosin 2×)",
"metadata": {}
},
{
"id": 278,
"image": "PMC2364253_fig3_21702.jpg",
"report": "Immunohistochemical staining patterns for GalNAc-T3. Normal bronchial epithelial cells (A) and bronchial gland cells (B) showed GalNAc-T3 expression. GalNAc-T3 expression was found diffusely in the cytoplasm of tumour cells or localised in the Golgi apparatus in an adenocarcinoma (C), but not seen in a squamous cell carcinoma (D). Scale bar=20 μm.",
"metadata": {}
},
{
"id": 279,
"image": "PMC2361256_fig3_21388.jpg",
"report": "Immunohistochemistry on lymph nodes containing carcinomatous cells detected after HES staining (right) after incubation with an anticytokeratin monoclonal antibody (left) (final magnification × 400).",
"metadata": {}
},
{
"id": 280,
"image": "PMC2538763_fig4_27840.jpg",
"report": "Localisation of junctional proteins and phospho-Smad2 in Smad7-induced liver metastases. Tissues from normal livers of parental and vector control cells injected mice and liver metastases from Smad7-expressing clones injected mice were collected 33 days after splenic injection. (A) Shows staining with H&E, proliferation marker Ki67 and Tunnel. (B) Shows immunohistochemical staining for phospho-Smad2, E-cadherin, Claudin-1 and Claudin-4. Pictures were taken at original magnification of 630 × .",
"metadata": {}
},
{
"id": 281,
"image": "PMC3051156_fig3_89465.jpg",
"report": "Immunohistochemical study of TLR4, NF-κB, and MCP-1 on brain samples in (scale bar, 100 μm). The arrows show the positive neurons.",
"metadata": {}
},
{
"id": 282,
"image": "PMC2850372_pone-0010051-g002_61321.jpg",
"report": "Scanning electron micrographs of the panel of particles of different geometries used for the attachment study.(a–c) Spheres of 0.5 µm, 1 µm and 3 µm respectively; (d–f) Rods stretched from 0.5 µm, 1 µm and 3 µm spheres respectively; (g–i) Oblate ellipsoids Rods stretched from 0.5 µm, 1 µm and 3 µm spheres respectively. The volume of the particles in a particular column is constant and corresponds to the volume of the sphere in that column. (Scale bar 5 µm for all images)",
"metadata": {}
},
{
"id": 283,
"image": "PMC3045890_F5_88331.jpg",
"report": "Localization of Physcomitrella hexokinases to mitochondria. GFP fluorescence is show in green and the mitochondria specific dye MitoTracker® in orange. The white bars represent 1 μm.",
"metadata": {}
},
{
"id": 284,
"image": "PMC2931510_F2_72530.jpg",
"report": "Cutaneous biopsy specimen. Periodic acid-Schiff staining with the presence of Cryptococcus neoformans (PAS-positive spherules with prominent capsules in a zone of clearance or \"halo\" around the cells, original magnification × 630).",
"metadata": {}
},
{
"id": 285,
"image": "PMC3045294_F7_88194.jpg",
"report": "ROS is not increased in arrested bps1 leaves. (A). Hydrogen peroxide, visualized using DAB, was found in necrotic lesions and associated with vascular tissue, but it was not elevated in the bps1 leaf. (B) Superoxide, visualized using NBT staining, was found associated with vascular tissue, but it was not elevated in the bps1 leaf. Bars = 200 μm.",
"metadata": {}
},
{
"id": 286,
"image": "PMC2678080_F1_38024.jpg",
"report": "Cytoplasmic EABA in PTC tissue. a) Cytoplasmic EABA in papillary thyroid carcinoma cells (LSAB+); objective magnification 5×; b) No reaction in the same sample of PTC (EnVision); objective magnification 5×.",
"metadata": {}
},
{
"id": 287,
"image": "PMC2982818_pone-0014010-g001_78549.jpg",
"report": "EBP and lipid rafts are colocalized at the plasma membrane.EBP and lipid rafts localization were analyzed using confocal microscopy as described in the Methods section. EBP appears as a red staining, lipid rafts as a green staining and the colocalization as a yellow staining. The scale represents 10 µm.",
"metadata": {}
},
{
"id": 288,
"image": "PMC2360262_fig3_21104.jpg",
"report": "(A) Fluorescence-activated cell sorting of transduced cells expressing mitochondrially localised red fluorescent protein. The cells from the gate designated M1 were used in subsequent experiments. (B) Micrographs of the labelled MG63 OS cells. (C) Micrographs of the tumour spheres derived from culture in clotted human plasma. (D) A sectioned tumour sphere (red) immunostained for the detection of Dkk-1 (green). Nuclei are stained with DAPI (blue). The isotype control is presented on the right.",
"metadata": {}
},
{
"id": 289,
"image": "PMC3006376_F4_81896.jpg",
"report": "The histological examination confirmed the diagnosis of pituitary lymphoma. Figures A and B shows infiltrative large-sized lymphocytes with occasional mitotic. The immunohistocemical tests were positive for the B-cell CD20 marker (C) and negative for the T-cell marker CD3 (D).",
"metadata": {}
},
{
"id": 290,
"image": "PMC2963642_pone-0013586-g003_76774.jpg",
"report": "Mammary tumor histology observed in Met mutants.A) Adenocarcinoma with solid patterns and squamous metaplasia in a FVB-MetM1248T/L1193V mouse; B) myoepithelioma in a FVB-MetM1248T/L1193V mouse; C and D) adenocarcinomas with tubular patterns from two individual FVB-MetM1248T mice; E) squamous cell carcinoma observed in a FVB-MetY1228C mouse; and F) an adenosquamous carcinoma observed in a FVB-MetY1228C mouse. All H&E images were taken at 200× magnification.",
"metadata": {}
},
{
"id": 291,
"image": "PMC2464599_F5_25416.jpg",
"report": "Subcellular distribution of CGI-146 protein tagged with GFP. The CGI-146-GFP fusion protein localized in Golgi complex marked with fluorescein isothiocyanate (A). Red fluorescence of mitochondria were stained with the mitochondrial-specific dye, Mito-Tracker Red (B) and blue fluorescence of nuclei were stained with Hoechst33342 (C). The overlay images were produced by merging all three signals together (D). The control micrographs (E-H) showed the GFP in the cytoplasm. Bars represent 30 μM.",
"metadata": {}
},
{
"id": 292,
"image": "PMC2779586_ppat-1000682-g003_51264.jpg",
"report": "Distribution of CD244 in PBMCs of patients with HAM/TSP.After the culture for 8 hours, PBMCs were stained with antibodies against perforin, CD244 and CD48, and visualized through microscope. Two representative 3D images were shown in A and B. The image shows DAPI (blue), perforin (green), CD244 (orange) and CD48 (purple). In addition to DAPI and perforin (left), CD244 (middle) and CD48 (right) are merged. The white arrows indicate CD244 clustering at the cell contact area.",
"metadata": {}
},
{
"id": 293,
"image": "PMC2814232_fig4_55950.jpg",
"report": "Hyaluronidase detection on tryptic soy agar supplemented with hyaluronic acid. S. aureus ATCC 33753 (a), S. aureus Newman (b), S. epidermidis ATCC 12228 (c), and a mixture of all three (d). Colonies of S. aureus Newman did not adhere to the agar surface when acetic acid was removed from the plates for photographic documentation.",
"metadata": {}
},
{
"id": 294,
"image": "PMC2610034_F1_31800.jpg",
"report": "Protein expression of Trail, p21 and Ccnb1 in serous epithelial benign, low malignant potential and LG ovarian tumors. Representative images of immunoperoxidase-stained tissue cores are shown for each protein and tumor classes (20× magnification). Cytoplasmic and nuclear staining was observed for each of these proteins.",
"metadata": {}
},
{
"id": 295,
"image": "PMC3027648_pone-0016387-g005_85574.jpg",
"report": "LF82 colonization affects the nematode epithelium.Electron micrographs of C. elegans thin sections. (A–C) Nematodes feeding for three days on OP50, LF82 and LF82Δhfq, respectively. (D–L) Nematodes feeding for five days. MV, microvilli; TW, terminal web; Ec, E. coli bacteria. Damaged apical microvilli are indicated by black arrows. Scale bars represent 5 µm.",
"metadata": {}
},
{
"id": 296,
"image": "PMC2698848_F2_40319.jpg",
"report": "Nuclear localization of four BnWRKY proteins. Transgenic (T2) Arabidopsis roots of five-day old seedlings were observed under confocal microscope. Panels A-E represent the subcellular localization of BnWRKY6-sGFP, BnWRKY25-sGFP, BnWRKY33-sGFP, BnWRKY75-sGFP and pCsGFPBT vector control, respectively. In each case, the extreme left panel is GFP fluorescence, the middle bright field and the right represents an overlay of the two images.",
"metadata": {}
},
{
"id": 297,
"image": "PMC2861821_F0001_63214.jpg",
"report": "Cytospin smears from Case 1 showing papillary fragments (a. Papanicolaou × 200) of cells with vesicular nuclei and prominent nucleoli (b. Papanicolaou × 400). Focal acinar arrangement is also noted (c. May-Grünwald-Giemsa × 400). Histologic section of the same case showing papillary renal cell carcinoma (d. HandE × 200)",
"metadata": {}
},
{
"id": 298,
"image": "PMC2930628_F5_72354.jpg",
"report": "NMDA-induced ultrastructural changes in RGCs at 7 days where necrotic cell in the form of highly electron-dense neuronal debris (Red star, A & B, Bar = 2 μm) is seen lying adjacent to numerous membrane-bound microtubule-rich neuritic processes (C, red triangle, Bar = 2 μm) identified as dendrites under high power (D, red triangle, Bar = 500 nm); Figure E and F show reactive microglia surrounding the dendritic sprouts. (Bars = 2 μm).",
"metadata": {}
},
{
"id": 299,
"image": "PMC2667487_F1_37109.jpg",
"report": "B1R distribution in thoracic spinal cord of STZ-treated rats was shown by confocal microscopy with [Nα-Bodipy]-des-Arg9-BK. Shown are pictures from low (i) to high magnification (V) of the dorsal horn. Scale bars = 200, 50, 20, 5 and 2.5 μm, respectively from (i) to (V). Pictures are representative of a minimum of 4 sections per rat from 4 different STZ-diabetic rats.",
"metadata": {}
},
{
"id": 300,
"image": "PMC2875709_F0001_64775.jpg",
"report": "En bloc procurement of kidneys with aorta and vena cava. Note the laceration on ventral surface of right kidney",
"metadata": {}
},
{
"id": 301,
"image": "PMC2257935_F4_18332.jpg",
"report": "Disruption of redA impairs development at mound stage. (A) Exponentially growing AX4 wild type cells and the mutants redA- and redA-KO were starved on filter pads and photographed at the indicated times (h) after starvation. (B) AX4 fruiting bodies and redA- yellow mounds after 48 hours starvation on filter pads are shown at lower (left) and at 5× higher magnification (right).",
"metadata": {}
},
{
"id": 302,
"image": "PMC2584955_fig5_30365.jpg",
"report": "The effect of direct association of Cav-1 with integrin β1 on integrin β1-mediated survival. Immunofluorescence staining of integrin β1 (the first column), Cav-1 (middle column), and the merged images (the right column) of EV and CavS cells under attached (top) or suspended condition (bottom). Image was taken with confocal microscopy (magnification × 630).",
"metadata": {}
},
{
"id": 303,
"image": "PMC3025920_pone-0016081-g001_85344.jpg",
"report": "The change of liver fibrosis in mouse model.A. Representative H&E-stained, Azan-stained, Ag-stained, and EVG-stained histological sections of liver from mice receiving olive oil alone or CCL4 in olive oil. Magnification is ×10. B. The expression level of mmu-miRNA in mouse liver with olive oil or CCL4 at 4W, 6W, and 8W respectively, by microarray analysis.",
"metadata": {}
},
{
"id": 304,
"image": "PMC2045666_F2_14542.jpg",
"report": "Electron microscopy observations of MYXV BT infected cells. A. Numerous virions are still adsorbed on the cell surface 8 h p.i.. B. Large cytoplasmic area without organite containing dense particles (5 h p.i.). C. Atypical Immature Virion (IV) (12 h p.i.). D. Intracellular Enveloped Virion (IEV) (12 h p.i.). Microscope: Hitachi UI12A, Magnifications, A: 35000; B: 15000; C and D: 90000.",
"metadata": {}
},
{
"id": 305,
"image": "PMC2860417_F0002_62985.jpg",
"report": "Microscopic appearance which shows neoplastic cells arranged in solid nests, cytologic atypia, and hyperchromatic nuclei suggestive of mesothelioma (H and E stain; ×40)",
"metadata": {}
},
{
"id": 306,
"image": "PMC1920558_pone-0000652-g007_12269.jpg",
"report": "T40/IDE digestion products form amyloid protofibrils.Electron micrographs of negatively stained T40/IDE total digest showing spherical (A) annular (B, I–II) and beaded (C, III) protofibrils. The bar represents 10 nm.",
"metadata": {}
},
{
"id": 307,
"image": "PMC2396177_F2_23303.jpg",
"report": "Immunohistochemical staining for macrophages (CD68) and T-lymphocyte subsets (CD5, CD4, and CD8) in lung tissue biopsy. (a) Lung tissue with well-formed granulomas, hematoxylin and eosin stain, 200× magnification. (b) Anti-CD68 (brown) and anti-CD5 (red) immunostaining, 400× magnification. (c) Anti-CD68 (brown) and anti-CD4 (red) immunostaining, 200× magnification. (d) Anti-CD68 (brown) and anti-CD8 (red) immunostaining, 40× magnification.",
"metadata": {}
},
{
"id": 308,
"image": "PMC2596090_F1_30924.jpg",
"report": "A cytology slide of the neoplasm of one of the patients. Note the numerous population of discrete round cells. (Diff Quick staining; magnification 100 ×).",
"metadata": {}
},
{
"id": 309,
"image": "PMC1914066_ppat-0030097-g006_12202.jpg",
"report": "In Vivo Expression of Loa22 in Liver and Kidney of Guinea Pigs Infected with L. interrogans Serovar Lai(A) Liver, (B) kidney. Histopathologic sections were stained by immunochemistry using Loa22 antiserum (×1,000). Intact organisms were found in biliary ducts (A) and in large number in Bowman's spaces and proximal tubules (B). Scale bar = 20 μm.",
"metadata": {}
},
{
"id": 310,
"image": "PMC2267690_f3_19022.jpg",
"report": "Histologic findings of the human corneal endothelial cell sheet. A and B: A cell sheet consists of a monolayer of cells that have consistent size. The scale bar in A is equal to 200 μm and in B is equal to 50 μm. C: Electron microscopic observation demonstrated desmosomes between cells (arrow). Bar=200 nm.",
"metadata": {}
},
{
"id": 311,
"image": "PMC2685139_F6_38870.jpg",
"report": "Histological analyses of female Calomys callosus infected i.p. with Paracoccidioides brasiliensis after bilateral ovariectomy. The tissue sections stained with haematoxylin-eosin were examined at a magnification of 200 X. In A and B – liver and spleen of animals 15 days post infection, C and D – liver and spleen 45 days post infection; E – liver 75 days post infection. Dead fungi cells are pointed with arrowheads. Giant cells are pointed with arrows.",
"metadata": {}
},
{
"id": 312,
"image": "PMC2129115_pone-0001334-g003_15303.jpg",
"report": "\nCebpd mRNA expression is localized to theca and interstitial cells.Dark-field photomicrographs of in situ hybridization analyses using Cebpd-specific sense and antisense RNA probes on sections from ovaries of 6 week-old mice treated for 2 days with PMSG followed by hCG for the indicated times. Outlined regions in the center panels are shown at higher magnification on the right.",
"metadata": {}
},
{
"id": 313,
"image": "PMC2803924_F3_54276.jpg",
"report": "Macroscopic and microscopic findings of the heart. A: cut surface of the heart. The heart weighed 780 g and showed numerous metastatic nodules and diffuse myocardial thickening, simulating hypertrophic cardiomyopathy. B: metastatic tumor cells invaded the myocardium with stromal edema (HE). C: immunohistochemical analysis for D2-40 demonstrated severe lymphatic infiltration of tumor cells.",
"metadata": {}
},
{
"id": 314,
"image": "PMC2860402_F0001_62978.jpg",
"report": "Cytologic examination of the bronchial wash showing a S stercoralis worm in a background containing some cellular debris (Papanicolaou stain ×400).",
"metadata": {}
},
{
"id": 315,
"image": "PMC2936339_F3_73110.jpg",
"report": "Representative pictures of fibrosis in non-tumorous tissue on sirius red staining (top), inflammatory foci on H&E staining (middle) and macrophages on F4/80 immunohistochemistry (bottom).",
"metadata": {}
},
{
"id": 316,
"image": "PMC2082377_F1_14966.jpg",
"report": "Caveolin-1 expression in breast cancer samples. A: Breast cancer sample without expression of Caveolin-1 in the epithelial tumor component. In contrast, expression of Caveolin-1 can be seen in myoepithelial cells as well as endothelial cells of entrapped vessels, serving as internal positive control (100× magnification). B: Breast cancer sample with strong expression of Caveolin-1 in the epithelial tumor component (400× magnification)",
"metadata": {}
},
{
"id": 317,
"image": "PMC2694596_F1_39815.jpg",
"report": "VEGFR-2 immunofluorescence staining in LHβTag transgenic retinoblastoma. Representative eyes from LHβTag mice at 4 (A), 10 (B), and 16 (C,D) weeks are shown. VEGFR-2 immunoreactivity is green and DAPI counterstaining is blue. GCL, ganglion cell layer; IPL, inner plexiform layer; INL, inner nuclear; ONL, Outer nuclear layer. Magnification (A) 200 X, (B) 100 X, (C) 200 X. (D) zoomed image from inset of C.",
"metadata": {}
},
{
"id": 318,
"image": "PMC2942852_F3_74138.jpg",
"report": "Expression of Bmi-1 protein in tissue by immunohistochemistry. A and B, only weak staining of Bmi-1 was detected in few normal esophageal epithelial tissue (arrow, normal epithelial cells). C and D, positive expression of Bmi-1 in esophageal carcinoma tissues (200× and 400× of magnification, respectively). E and F, representative case of higher expression of Bmi-1 in invasive front (arrow, 200× and 400× magnification, respectively). Bmi-1 expression mainly localized in nuclei of tumor cells.",
"metadata": {}
},
{
"id": 319,
"image": "PMC2924387_pone-0012269-g003_71722.jpg",
"report": "The GFP arising from vd-5′UTR/GFP transcripts accumulate specifically in chloroplasts.Confocal microscope observation of the N. benthamiana leaves expressing unmodified GFP (left panels), vd-5′UTR-GFP (central panels) or OE23/GFP (right panels). As observed, the vd-5′UTR/GFP mimics the cellular localization of the OE23/GFP construct that accumulates specifically in chloroplasts.",
"metadata": {}
},
{
"id": 320,
"image": "PMC2779103_pone-0008089-g001_51147.jpg",
"report": "Microscopic views of the liver in wild-type and IVA-PLA2-knockout mice.Wild-type and IVA-PLA2-knockout (KO) mice were fed normal (N) or high-fat (HF) diets for 8 (A) or 16 (B) weeks and fasted. Representative liver sections stained with hematoxylin-eosin are shown. IVA-PLA2 deficiency suppressed the hepatic fat deposition under the HF feeding. CV, central vein; PV, portal vein. Original magnification, ×4 and ×20.",
"metadata": {}
},
{
"id": 321,
"image": "PMC2822323_F0003_56777.jpg",
"report": "Histopathological examination of the biopsy specimen showing tumor cells in sheets and glandular arrangement with hyperchromatic nuclei (Haematoxylin and eosin, X 40).",
"metadata": {}
},
{
"id": 322,
"image": "PMC2259349_F4_18465.jpg",
"report": "Histologic assessment of tissue inflammation after intranasal Ad inoculation. After intranasal delivery of AdLuc, mice were sacrificed at days 1, 3, 7 and 12 and the organs were fixed, processed, and stained with H&E. Open arrow: inflammatory infiltrates in the liver (day 7) and lung (days 1, 3, 7 and 12). These microhistographs are representative of two mice per time point. Magnification: ×20.",
"metadata": {}
},
{
"id": 323,
"image": "PMC3042329_fig5_87692.jpg",
"report": "Stray light observed in the lens-coupled detector. A rectangular beam that was beyond the saturation level of the CCD camera was recorded to observe reflections and scatterings in the lens system. The dashed circle indicates a ‘ghost’ of the strong beam. This image is shown on a logarithmic scale.",
"metadata": {}
},
{
"id": 324,
"image": "PMC2925355_F1_71920.jpg",
"report": "A bone marrow biopsy showing the absence of hematopoietic tissue and its replacement with fat. Hematoxylin & eosin staining. 20× magnification.",
"metadata": {}
},
{
"id": 325,
"image": "PMC2861004_pone-0010397-g003_63055.jpg",
"report": "Visualization of neuronal axons in the infact area and in the contralateral hemisphere.Neuronal axons were visualized with antibodies against neurofilament proteins on sections from wild-type (A-D) and GFAP−/−Vim−/− (E-H) mice at P12, i.e. 3 days after hypoxia-ischemia. The frames indicate respective fields for higher magnification. Scale bar for A, C, E, G = 500 µm; for B, D, F, H = 50 µm.",
"metadata": {}
},
{
"id": 326,
"image": "PMC2569205_pone-0003562-g002_29028.jpg",
"report": "GFP+ cells cross the epithelium of the small intestine at 1 and 2 weeks of nursing.A, RT-PCR for GFP at 1, 2, 3, and 4 week time points of flushed small intestine of pups foster-nursed by GFPtg dams. The negative control used was small intestine from a non-GFP nursed B6 mouse and the positive control used was small intestine from a GFPtg mouse. B–E, sections of small intestine at weeks 1–4, respectively. Staining of GFP+ cells was enhanced with an anti-GFP antibody.",
"metadata": {}
},
{
"id": 327,
"image": "PMC2117009_F4_15167.jpg",
"report": "Immunoelectron microscopy for identification of BaMV CP and FMDV VP1 on the surface of virus particles. Leaf dips from C. quinoa infected with pBVP1 (A, B) or pBaMV-S (C) were obtained 10 days post-inoculation. Grids were first incubated with leaf extract and coated with diluted anti-BaMV CP serum (A) or anti-FMDV VP1 serum (B, C) followed by gold-labeled goat anti-rabbit IgG complexes. Grids were inspected in a Philips CM100 electron microscope. All bars represent 250 nm.",
"metadata": {}
},
{
"id": 328,
"image": "PMC2864752_pone-0010420-g004_63443.jpg",
"report": "Full-size (53-cm long) adult specimen of Notogoneus osculus Cope, about 13% longer than the tracemaker interpreted for the trace fossil FOBU-12718; scale in centimeters.Specimen is in Fossil Butte National Monument collection; photograph by Arvid Aase.",
"metadata": {}
},
{
"id": 329,
"image": "PMC2612653_F3_31890.jpg",
"report": "Lymph node biopsy demonstrates widespread infiltration by plasma cells.",
"metadata": {}
},
{
"id": 330,
"image": "PMC3076249_F1_92303.jpg",
"report": "Photomicrographs of liver biopsy, with hematoxylin/eosin (A, B, C) and reticulin stain (D), revealing a pattern of mild steatosis, moderate inflammatory changes and moderate to severe fibrosis (Ishak score = 5-6).",
"metadata": {}
},
{
"id": 331,
"image": "PMC1448204_F1_5195.jpg",
"report": "Changes in morphology during hormonal treatments at days 1, 5, 10, 15, and 30: Dex-induced changes in architecture were evident as early as d5 and persisted to d30. RA-induced changes were also evident at d5, continued to d15, but had reversed at d30. Concomitant Dex and RA administration resulted in septation similar to that of controls between d10 and d15 with continued normal appearance at d30. Dex: Dexamethasone. RA: all-trans-retinoic acid, (all images 40× magnification)",
"metadata": {}
},
{
"id": 332,
"image": "PMC2670261_F4_37442.jpg",
"report": "Localization of ALP107-273 in living cells. Fluorescence micrograph of a U2OS cell expressing α-actinin-CFP (A and red in C) and YFP-ALP107-273 (B and green in C). A higher magnification view of a region containing stress fibres is displayed in the bottom three panels (D, E, F). Bar 10 μm.",
"metadata": {}
},
{
"id": 333,
"image": "PMC539305_F1_922.jpg",
"report": "Isolation of an alveolar septum by laser-assisted microdissection and manipulation from a hemalaun stained frozen lung section (magnification 200×). A) Alveolar septum is selected for isolation. B) Laser photolysis is used to disconnect the cells from adjacent ones. C) Septum cells adhere tightly to the approximated sterile needle and can be transferred into a reaction tube.",
"metadata": {}
},
{
"id": 334,
"image": "PMC2778525_fig1_51044.jpg",
"report": "Immunostaining for oestrogen receptor in core needle biopsy and surgery specimens after neoadjuvant chemotherapy. (A) Staining of tumour cells in core-needle biopsy sample (CNB) staining positively for oestrogen receptor (ER). (B) Staining of tumour cells in surgical samples with ER-negative status after neoadjuvant chemotherapy (NAC). (C) Staining of tumour cells in CNB specimens with ER-negative status. (D) Staining of tumour cells in surgical samples with ER-positive status after NAC.",
"metadata": {}
},
{
"id": 335,
"image": "PMC2994931_pone-0014123-g004_80160.jpg",
"report": "Visualization of calcium flux using fluorescent microscopy.(A) Fluorescent image taken before trans-ACBD treatment showing non-fluorescent astrocytes when the cells were incubating in HBSS containing 50 mM glycine. Fluorescent image taken 5 seconds (B) and 10 seconds (C) after stimulation with 1 µM trans-ACBD showing fluorescent astrocytes following treatment with a selective NMDAR agonist.",
"metadata": {}
},
{
"id": 336,
"image": "PMC2335109_F4_20804.jpg",
"report": "Electron micrographs of S. parasanguinis bacteria. S. parasanguinis bacteria, L64R (A), P65R (B), I66N (C), L67T (D) mutant variants and wild type FW213 (E) were placed on grids, and negatively stained with 2% phosphotungstic acid pH7.0 and visualized by electron microscopy. White arrows point to the short fimbriae. Black arrows point to the long fimbriae. Scale bar = 100 nm.",
"metadata": {}
},
{
"id": 337,
"image": "PMC2694814_F6_39873.jpg",
"report": "Electron micrographs of the proximal tubule. Control animal showed a normal tubule and normal appearance of mitochodria (A). Loss of polarity of mitochondria and increased perinuclear clear space occurred in the endotoxemic kidney (B). Amrinone infusion restored mitochondrial integrity and intracellular edema (C). Scale Bar = 5 μm. Nu, nucleus; M, mitochondria; Ly, lysosome.",
"metadata": {}
},
{
"id": 338,
"image": "PMC2798714_fig1_53513.jpg",
"report": "FaDu cells immunostained for eIF4E showing cytoplasmic and nuclear localization. Cells were stained using eIF4E mAb conjugated directly to FITC (green) and nuclear marker DAPI (blue) as described [37, 47]. Micrographs were collected on laser scanning confocal microscope using 100X objective and 2x digital zoom.",
"metadata": {}
},
{
"id": 339,
"image": "PMC2787487_F3_52266.jpg",
"report": "Partially parallel or plexiform arranged spindelcells with slim and elongated nucleus without cytological sings of malignity (HE-staining; original magnification: 100×).",
"metadata": {}
},
{
"id": 340,
"image": "PMC2952312_fig2_75542.jpg",
"report": "Histological assessment of acute gastric mucosal injury induced by indomethacin (18 mg/kg, p. o.) in mice and its prevention by BT (40 mg/kg), TF (1 mg/kg), and Omez (3.0 mg/kg). The section of mice stomachs were dissected 4 h after the last dose of the respective test samples on the 3rd day of ulceration. Black arrows indicate mucosal damage.",
"metadata": {}
},
{
"id": 341,
"image": "PMC2781011_F4_51634.jpg",
"report": "Morphological patterns of boar sperm membrane lysis after incubation with the indicated detergents for 30 min at 4°C. Sperm samples were observed by light microscopy (A, phase contrast, magnification of 500) as well as by transmission electron microscopy (B, C). For further details see the Materials and Methods section. Each bar represents 200 nm. The quantitative evaluation of the microscopic investigations is given in Tab. 2.",
"metadata": {}
},
{
"id": 342,
"image": "PMC2902752_fig3_68648.jpg",
"report": "Time-dependent effects of infection of MTH52c with GLV-1h68 at an MOI of 1.0. (BF) Transmitted light view of virus-infected MTH52c cells; (GFP) expression of GFP in infected cells detected by direct fluorescence; (PI) propidium iodide staining of dead cells; (Merged) colocalization of GFP with the dead cells is shown in the merged imaged. All pictures in this set were taken at the same magnification. Scale bars represent 0.1 mm.",
"metadata": {}
},
{
"id": 343,
"image": "PMC2744704_F1_46076.jpg",
"report": "Histology of baseline (A, C, E) and endocrine-treated (B, D, F) DCIS from patient H-20 (magnification: 100×). A, B: H&E stain of baseline (A) and treated (B) samples. The treated DCIS is less distended and demonstrates increased periductal sclerosis and inflammation compared to baseline. C, D: Ki67; reduction in Ki-67 after treatment compared to baseline; E, F: CD68 (inset: 400×); increased CD68-positive macrophages after treatment compared to baseline.",
"metadata": {}
},
{
"id": 344,
"image": "PMC2779192_F2_51201.jpg",
"report": "PGRN is localized within motor neurons of the mouse lumbar spinal cord. PGRN is localized within motor neurons of the mouse spinal cord. Labelling of paraffin-fixed cross-sections of murine spinal cord with SMI32 marker against hypo-phosphorylated neurofilaments (left panel), which is a marker for motor neurons, and anti-PGRN (middle panel). Merged channels are shown in the right panel. (a) at original magnification (40×), (b) at magnification (63×).",
"metadata": {}
},
{
"id": 345,
"image": "PMC3017074_F2_83319.jpg",
"report": "Trophoblastic islands in the myometrium (haematoxylin and eosin, original magnification × 40).",
"metadata": {}
},
{
"id": 346,
"image": "PMC3058109_F5_90290.jpg",
"report": "Immunohistochemical reaction for macrophages in the liver of mice inoculated with E. histolytica or E. dispar treated and untreated with dexamethasone. Scarcity of immunoreactive macrophages (arrowheads) adjacent to the debris-rich hepatic necrosis (N) in the groups EGG-DEX (b) and MCR-DEX (d) compared to groups EGG (a) and MCR (c). Non-necrotic hepatic parenchyma (H). Bar 50 μm. Harris's haematoxylin counterstained.",
"metadata": {}
},
{
"id": 347,
"image": "PMC1274344_F1_3725.jpg",
"report": "Transmission electron microscopy pictures of asbestos-cement (A) and chrysotile (B) samples. (Magnification: 2000×)",
"metadata": {}
},
{
"id": 348,
"image": "PMC2374696_F6_22029.jpg",
"report": "Microvesicles budding from the flagellar pocket and plasma membrane of leishmania. Stationary phase leishmania promastigotes were fixed and coated for scanning electron microscopy as described in Materials and methods. (a) A leishmania promastigote, (b) 10× magnification of the exposed flagellar pocket region of panel a (square) after stage rotation, and (c) a promastigote in the process of differentiating into an amastigote. Arrowheads point to microvesicles.",
"metadata": {}
},
{
"id": 349,
"image": "PMC2582510_f10-co15-5-225e62_30034.jpg",
"report": "Manual superposition of whole-mount histopathology and corresponding digital photograph. Red and green contours on the photograph represent specimen edge and naked-eye gross tumour respectively. This superposition illustrates that some mismatch remains, which could be the result of changes in conformation and specimen dimension during sectioning and processing.",
"metadata": {}
},
{
"id": 350,
"image": "PMC1277860_f8-ehp0113-000170_3785.jpg",
"report": "SEM preparation (magnification, 1,000×) after exposure in serum-free medium to suspension of C/Fe particulates. Note no tendency to agglomerate. Bar = 10 μm.",
"metadata": {}
},
{
"id": 351,
"image": "PMC2527131_pone-0003192-g005_27116.jpg",
"report": "Immunohistology.Higher magnification images (100×) of portions of the sections shown in figure 3. Estimates of percentages of B cell engraftment are done at this magnification by comparing the percentage of the splenic section staining with anti-CD20.",
"metadata": {}
},
{
"id": 352,
"image": "PMC2375898_F2_22382.jpg",
"report": "Transmission and fluorescence microscopy images of ALN frozen sections. Nude mice were injected with 20 pmol of QDs or PBS (control) in the distal part of the right anterior paw. Panels A, B: transmission and fluorescence images of ALN control; Panels C, D: transmission and fluorescence images of ALN 5 min after QDs injection (40 × enlargement). ALN: Axillary Lymph Node; QDs: Quantum Dots.",
"metadata": {}
},
{
"id": 353,
"image": "PMC2833257_fig2_58580.jpg",
"report": "(A) Example of immunostaining for matrix metalloproteinase (MMP)-14 in prostate benign pathology. Magnification: × 200. (B) Example of immunostaining for MMP-14 in prostate carcinoma. Magnification: × 200.",
"metadata": {}
},
{
"id": 354,
"image": "PMC2245911_F3_17709.jpg",
"report": "Prominent restrictive vascular changes (H&E, original magnifications ×100).",
"metadata": {}
},
{
"id": 355,
"image": "PMC2853493_F3_61792.jpg",
"report": "Electron micrographs of PB and BV VLPs. A: PB VLPs, scale bar 500 nm. B: BV VLPs, same scale. Arrows show contamination by co-purified recombinant baculovirus in the BV sample. Insets: individual particles with diameter shown. PB VLP: 139 nm; BV VLP: 129 nm.",
"metadata": {}
},
{
"id": 356,
"image": "PMC3011911_f05_82561.jpg",
"report": "Leaf litter of rubber plantation during the leaf sprouting and flowering phase, a) Lower leaf litter layers with late stages of Vth instar larvae, larval exuviate and pupae, b) & c) Luprops trisits fed light green leaves and untouched dark green leaves in leaf litter and d) leaf litter with fallen flowers.",
"metadata": {}
},
{
"id": 357,
"image": "PMC2843720_pone-0009809-g002_60115.jpg",
"report": "Electron micrographs of negatively stained AP205-Ang II VLPs.AP205 VLPs displaying the Ang II peptide fused to the C-terminus (AP441 – short linker, AP442 – long linker), or the N-terminus (AP446 – short linker, AP447 – long linker) of AP205 coat protein.",
"metadata": {}
},
{
"id": 358,
"image": "PMC1895600_fig2_11747.jpg",
"report": "Immunoreactivity of COX-1 at E18. IHC demonstrating a) strong immunoreactivity in the syncytiotrophoblast and some cytotrophoblast cells of the LZ; and b) the GCs (arrowed) in the JZ. The spongiotrophoblast cells (S) are notably weakly stained. Fluorescent double-labelling for COX-1 and HNE showed strong co-localisation in the trophoblast of the LZ (c); and a band of GCs in the JZ (d). Note autofluorescence (*) in maternal erythrocytes in the blood spaces. Blue, DAPI. Scale bars: 50 μm.",
"metadata": {}
},
{
"id": 359,
"image": "PMC2857828_F3_62531.jpg",
"report": "Effect of inhibitory neurotransmitters and neuromodulators on the motility of microglia in spinal dorsal horn. (A-F). Local application of 1 mM GABA, Glycine, 5-HT, noradrenalin (NA), acetylcholine agonist carbachol and morphine had no effect on microglia motility. The merged picture is the overlay of imaging at 0 min (green) and 30 min (red) after drug local application. Note that (F) showed the result recorded on typical amoeboid cells. Bars equal to 20 μm.",
"metadata": {}
},
{
"id": 360,
"image": "PMC3018382_F6_83675.jpg",
"report": "HE staining of the control (non-HBO, non-fibrin) group show irregular fibrous repair (R). At 12 weeks, original magnification × 25.",
"metadata": {}
},
{
"id": 361,
"image": "PMC2678864_F0006_38089.jpg",
"report": "The histopathology and β-catenin-immunohistochemistry findings of BCAC from mouse (a and b) and human (c and d) colon specimens. BCAC (circled) can be detected on hematoxylin and eosin stain-stained sections (a and c) based on the intensive basophilic nuclei of atypical cells and a few goblet cells in the lesion. β-catenin-immunohistochemistry shows intensive reactivity in the nuclei and/or cytoplasms of atypical cells that form BCAC (b and d)",
"metadata": {}
},
{
"id": 362,
"image": "PMC1373622_F4_4572.jpg",
"report": "CT26 cell morphology during the course of FasL analysis. Cell lines were seeded at ~2 × 105 cells/ml in 6 well plates to achieve 20% confluency 18 hours later. This point was defined as 0 hr. After 72 hrs, cells had reached ~80–90% confluency.",
"metadata": {}
},
{
"id": 363,
"image": "PMC2743194_ppat-1000589-g004_45917.jpg",
"report": "Electron micrographs of kDNA networks from TbPIF5 overexpression cells.(A) and (B), kDNA isolated from wild-type cells. (C–E), kDNA isolated from TbPIF5 overexpression cells six days after induction. Arrow, maxicircle loops. Bar, 500 nm.",
"metadata": {}
},
{
"id": 364,
"image": "PMC2366065_pone-0002167-g002_21813.jpg",
"report": "Fluorescence in situ hybridization with 45S rDNA as the probe shows that 45S rDNAs (green) are the sites of chromosome lesions in meristematic cells of root tips in diploid Lolium perenne cv. Player.The number of lesion sites varys in different cells from 0 to 6 due to the existence of multiple 45S rDNA sites. The left panel A1–G1: black layers and the right panel A2–G2: color images by merging red layers and green layers. Arrows indicate lesion sites. Bar = 5 µm.",
"metadata": {}
},
{
"id": 365,
"image": "PMC2726283_fig5_43383.jpg",
"report": "FSB labels filamentous tau inclusions in vivo. Five month-old human P301S tau transgenic mice received a single intravenous injection of 0.1% FSB. One hour (A), 2 h (B) and 4 h (C) after the injection the mice were perfused, the spinal cord sectioned and analysed by confocal microscopy. Scale bar, 150 μm. (D), Motor neurons labelled following the intravenous injection of FSB were also immunoreactive with anti-tau antibody AT8. Scale bar, 60 μm.",
"metadata": {}
},
{
"id": 366,
"image": "PMC2940843_pone-0012760-g004_73831.jpg",
"report": "Histologic examination of liver and spleen sections from TCRV-infected AG129 mice.Representative A) liver and B) spleen histopathology on day 8 of TCRV infection in AG129 mice. C) Liver and D) spleen tissue from healthy sham-infected mice. Tissues were stained with hematoxylin and eosin.",
"metadata": {}
},
{
"id": 367,
"image": "PMC2409904_fig2_23833.jpg",
"report": "(A–C) Gastric carcinoma of the G-phenotype. (A) Histological features (H&E, original magnification × 400). (B) Human gastric mucin is expressed in the cancer cell cytoplasm (45M1, original magnification × 400). (C) MUC6 glycoprotein is also expressed in the cancer cell cytoplasm (CLH5, original magnification × 400).",
"metadata": {}
},
{
"id": 368,
"image": "PMC2850933_f3_61395.jpg",
"report": "The morphology and cell size of HCECs cultured in the CEM group and the 25%ESC-CM group. The 25%ESC-CM group maintained the morphology and cell size of HCECs until passage (P6).",
"metadata": {}
},
{
"id": 369,
"image": "PMC2820092_pone-0009160-g004_56494.jpg",
"report": "Pathological signs of HEV infection in hematoxylin and eosin stained liver sections.(A & B) Liver sections from a group 2GDC54-18 rabbit showing localized extensive hepatocellular necrosis (magnification 10× and 20×, respectively). (C) Liver section from a group RH4 rabbit showing irregularly distributed multifocal lymphohistiocytic infiltrates (20×). (D) Liver section from a control rabbit showing no visible pathological signs of HEV infection (20×).",
"metadata": {}
},
{
"id": 370,
"image": "PMC2876065_F4_64837.jpg",
"report": "Transmission electron microscope observation of intracellular QD distribution in ESCs and MEFs. Representative cells at 6, 24, 48 hours after labeling are shown. Higher magnifications of the squared area in the left columns at each time point are shown in the right columns for both ESCs and MEFs. Black arrows: vesicles; White arrows: QD aggregates; Bars: 500 nm.",
"metadata": {}
},
{
"id": 371,
"image": "PMC2474615_F7_25519.jpg",
"report": "Three-dimensional models of three-finger toxins from S. catenatus edwardsii venom gland transcriptome. Top row shows the solid ribbon models. Segments are color coded as in Figure 1. Middle and bottom (180° rotation) rows show the electrostatic potential of both the surface. The positively and negatively charged residues are shown in blue and red colors, respectively, and the hydrophobic residues are shown in white color.",
"metadata": {}
},
{
"id": 372,
"image": "PMC2856673_pone-0010123-g001_62414.jpg",
"report": "FN and LMN induce changes in DC morphology.\nA, SEM images of ECM-treated DC taken after 48 h of culture over FN or LMN-coated coverslips. Different magnifications were used to better visualize the whole cell morphology. B, Cell perimeter measurements based on light microscopy images. Results represent average values of at least 50 cells in each condition plus standard deviations.",
"metadata": {}
},
{
"id": 373,
"image": "PMC3045344_F3_88204.jpg",
"report": "Histopathological observation of the lungs of virus-inoculated mice. On day 8 after infection, the lungs were removed from the mice under anesthesia and subjected to histopathological examination. Lung section of the mouse co-inoculated with mannan is also shown.",
"metadata": {}
},
{
"id": 374,
"image": "PMC2741108_fig5_45787.jpg",
"report": "Analysis of cytoskeletal reorganisation by confocal microscopy on PANC-1 PC cells after 48 h exposure to ZOL (15 μM). The figure shows actin architecture rearrangements in cortical rings. The cells were examined under a confocal microscope at a magnification of × 100. The experiments were performed at least three times and the results were always similar.",
"metadata": {}
},
{
"id": 375,
"image": "PMC2912265_F1_70173.jpg",
"report": "Sections of colorectal adenocarcinoma with results of the immunostaining: CD3, CD4, CD8, CD56, Foxp3 (magnification × 100). The CD56- section (magnification X40) reveals no CD56 positive immune cells (considered as NK negative tumor) but staining of Meisner plexus used as interne positive control.",
"metadata": {}
},
{
"id": 376,
"image": "PMC2395280_fig9_23263.jpg",
"report": "Immunohistochemical staining of a skin biopsy. A skin biopsy taken 3 days after the administration of MDX-H210 (patient #21) was stained for macrophages and PMN. Macrophages (arrow) were stained with a CD68 antibody, and PMN (arrow) with chloroacetate esterase. A skin biopsy from the same patient taken before the start of treatment showed no relevant infiltration with macrophages and PMN.",
"metadata": {}
},
{
"id": 377,
"image": "PMC2953520_pone-0013334-g013_75677.jpg",
"report": "SEM and EDS results of ceratopsian specimen BMR P2006.4.1.A) SEM image at 650× magnification of pliable ceratopsian vessels. B) SEM image at 4,500× magnification of framboids identified in pliable ceratopsian vessels. C) EDS signature of framboids, rich in iron.",
"metadata": {}
},
{
"id": 378,
"image": "PMC2667431_F4_37095.jpg",
"report": "Morphological observation with May-Grunwald-Giemsa's staining at actual magnification 100×. HepG2 cells were treated for 24 (A), 48 (C) and 72 (E) hours with 12.5 μg mL-1 of P. sarmentosum ethanolic extract while untreated HepG2 cells were grow in complete medium for 24 (B), 48 (D) and 72 (F) hours. The white arrows indicated apoptotic bodies. The figures shown are representative of three independent experiments (n = 3).",
"metadata": {}
},
{
"id": 379,
"image": "PMC2731857_pone-0006916-g003_44299.jpg",
"report": "Neurofilament whole-mount immunohistochemistry of the skin from heads of mouse embryos.Shown are sagittal views of the heads of wild-type (wt, A, C) and palladin-deficient embryos (ko, B, D) at age E13.5. Arrows indicate immunoreactive axons (magnification, 20×).",
"metadata": {}
},
{
"id": 380,
"image": "PMC2238754_F5_17502.jpg",
"report": "VP1 detection in type II cells. The cells were double-stained for VP1 and Pro-SP C as described in Materials and Methods. An SO lung is shown at the top row and ARDS lung in the bottom row. VP1 was detected by Cyte5 (red fluorescence, left panels) and Pro-SP C by FITC (green fluorescence, middle panels). The upper and lower right images show co-localization of both stainings inside alveolar type II cells (yellow). Shown at ×100 magnification",
"metadata": {}
},
{
"id": 381,
"image": "PMC3052562_f4_89573.jpg",
"report": "Effect of siRNA depletion of cellular mRNA export factors on viral mRNA localization. 293T cells were transfected with siRNAs against the labelled proteins, infected with virus and positive-sense transcripts from the indicated segments detected by FISH followed by confocal microscopy.",
"metadata": {}
},
{
"id": 382,
"image": "PMC2895880_F0001_68036.jpg",
"report": "Metaplastic cells with an increased nuclear-cytoplasmic ratio and moderately hyperchromatic chromatin that on biopsy showed CIN1 (Conventional smear, Papanicolaou stain × 600).",
"metadata": {}
},
{
"id": 383,
"image": "PMC2797328_pone-0008532-g003_53218.jpg",
"report": "Avicin D induces clustering of Fas in lipid rafts.Jurkat cells were treated with 2 µg/ml of avicin D for 0–8 h. After the treatment, the cells were fixed and stained with FITC-CTxB subunits to identify lipid rafts (green fluorescence) and with anti-Fas antibodies to identify Fas (red fluorescence). Area of colocalization between membrane rafts and Fas in the merge panels is yellow.",
"metadata": {}
},
{
"id": 384,
"image": "PMC1524950_F8_6311.jpg",
"report": "Quadruple-labelling (accumulation of fluorescent tracer plus triple-labelling immunohistochemistry) of DRG neurons after DiI injection into the pleural cavity, showing A) ASIC3+/TRPV1-/NF68-, B) ASIC3+/TRPV1-/NF68+, C) ASIC3+/TRPV1+/NF68-, and D) ASIC3-/TRPV1+/NF68+ patterns of immunoreactivity. Bar represents 50 μm throughout.",
"metadata": {}
},
{
"id": 385,
"image": "PMC2556647_F2_28247.jpg",
"report": "A. Mucinous adenocarcinoma B. IHC results. Diffuse CK20 positivity and CK 7 negativity (not shown), reinforcing a metastatic colorectal adenocarcinoma. C. Metastatic 'signet-ring' cell adenocarcinoma from colorectum. Infiltrating 'signet-ring' cells in a desmoplastic stroma. Inset, showing discrete mucicarmine positivity, highlighting intracytoplasmic mucin in the tumor cells. D. CK20 positivity in the signet-ring cells. E. Diffuse CEA expression. CK 7 was negative (not shown).",
"metadata": {}
},
{
"id": 386,
"image": "PMC2265554_pone-0001828-g005_18682.jpg",
"report": "Lung metastases' macroscopic analysis.At 45 days after tumor cells injection, the animals injected with K5L and K5L-Luc cells were sacrificed. Macroscopic surface metastases were observed in all lungs (A). The lungs of the mice injected with K5L cells were removed and stained with India ink (B).Using IVIS we analyzed lungs of animals injected with K5L-Luc cells (C). When the isolated lungs were exposed to X-ray, the latter highlighted calcified metastasis (D, yellow arrow).",
"metadata": {}
},
{
"id": 387,
"image": "PMC2494609_pgen-1000158-g007_26216.jpg",
"report": "Subcellular Localization of Mutant Forms of PBG.Confocal microscopic observation of GFP fluorescence in transgenic Arabidopsis seedlings. Hypocotyl epidermal cells of 3-day-old seedlings were observed. Dark-grown seedlings (upper), those treated with cW for 2 min (middle) and those treated with cR for 24 hr (lower) are shown. The bar indicates 10 µm.",
"metadata": {}
},
{
"id": 388,
"image": "PMC3024261_ppat-1001261-g003_84909.jpg",
"report": "Appressorium formation assays with intact rice leaves.\nA. Rice leaves inoculated with conidia from strains Ku80, M6 (Momsb2), and MS88 (Mosho1 Momsb2). Melanized appressoria were observed 24 hpi. B. Appressoria formed by the same set of strains on rice leaf surface examined under SEM. The mutants produced appressoria at the tip of long germ tubes. Bar = 10 µm. Arrows marked appressoria.",
"metadata": {}
},
{
"id": 389,
"image": "PMC2586027_F6_30505.jpg",
"report": "Disruption of tight junctions by recombinant toxins. HCT-8 cells on transwells were cultured untill the formation of tight junctions. The polarized monolayers were untreated (A) or treated with 300 ng/ml of rTcdA for 2 hr (B), 4 hr (C), and 6 hr (D); or with rTcdB 300 ng/ml for 2 hr (E), and 4 hr (F). Cells on the transwell membrane were fixed and stained with anti-oocludin and fluorochrome-conjugated secondary antibodies, and then visualized under a confocal microscope.",
"metadata": {}
},
{
"id": 390,
"image": "PMC3019156_F5_84006.jpg",
"report": "Electron micrographs of cells in large scale culture at various phases, and purified magnetosomes. a, b, c, d,: 1-2 hr, 3-4 hr, 15-16 hr, and 24 hr, respectively, after DO became undetectable. e: purified magnetosomes. For each sample more than 20 micrographs were got and one representative image was selected.",
"metadata": {}
},
{
"id": 391,
"image": "PMC2850546_fig3_61373.jpg",
"report": "High magnification demonstrating characteristic cribriform pattern in which multiple cysts are embedded in an island of basaloid cells. Three representative cysts are shown by arrows (Fresh frozen tissue, H & E, original magnification ×100).",
"metadata": {}
},
{
"id": 392,
"image": "PMC2233636_F3_17334.jpg",
"report": "Immunohistochemical aspects of β-catenin antigen stain; original magnification, 40×. (A) Pleomorphic adenoma in human salivary gland with membrane and cytoplasmic β-catenin stain; (B) Mixed tumour in canine mammary tumour with membrane and cytoplasmic β-catenin stain; (C) Carcinoma ex-pleomorphic adenoma in human salivary gland showing β-catenin nuclear stain (arrows); (D) Metaplastic carcinoma in canine mammary gland showing β-catenin nuclear stain (arrows).",
"metadata": {}
},
{
"id": 393,
"image": "PMC3042371_F4_87714.jpg",
"report": "Histological and immunohistochemical profile of PECs. Tumor cells showed marked coagulative necrosis (Hematoxylin-Eosin, x40) (a). In PECs, SMA had a focally cytoplasmic positivity (x40)(b). Nuclear MIB-1 reactivity was documented in PECs (x200)(c). We observed a strong and diffuse membrane reactivity for CD31 in tumor cells (x40)(d). The tumor was negative for all other markers mentioned, including S-100, CKAE1/AE3, CK5, CD30.",
"metadata": {}
},
{
"id": 394,
"image": "PMC2938369_pone-0012105-g002_73407.jpg",
"report": "Histological examination of the thymus from Hexb\n+/−\nFcRγ\n+/+, Hexb\n−/−\nFcRγ\n+/+ and Hexb\n−/−\nFcRγ\n−/− mice.H&E staining of paraffin-embedded thymic sections from 13 week old Hexb\n+/−\nFcRγ+/+, 15 week old Hexb\n+/−\nFcRγ+/+, Hexb\n−/−\nFcRγ+/+ and Hexb\n−/−\nFcRγ\n−/− mice. The bottom panels show a higher magnification image of the framed area in the top panels. Cor, cortex; Med, medulla. Arrows indicate vacuolated cells. Scale bars, top panel, 100 µm; bottom panel, 50 µm.",
"metadata": {}
},
{
"id": 395,
"image": "PMC3035259_f1_86562.jpg",
"report": "Unique colony morphology (Left) and scanning (Center) and transmission (Right) electron micrographs of E. medicae strain WSM419.",
"metadata": {}
},
{
"id": 396,
"image": "PMC2170440_F4_15744.jpg",
"report": "Electron micrographs of infected cells. A. K6 cell infected with HHV-6 (arrows) with margination of the chromatin in the nucleus and extensive vascularization. B. K2 cell showing HIV-1 particles (arrows). It is unclear whether the particles are outside the cell or in a vacuole inside the cell. C. K5 cell showing partial HCV particles inside a vacuole (arrow). D. K6 cell showing HCV particles (arrows). E. Inset showing HCV from Figure 4D.",
"metadata": {}
},
{
"id": 397,
"image": "PMC2565272_fig15_28658.jpg",
"report": "Histopathological photo of lung from a group 3 rat exposed to chrysotile and the sanded component (40 × magnification). An increased number of macrophages are observed with sometimes two or three per alveolus.",
"metadata": {}
},
{
"id": 398,
"image": "PMC2039726_F6_14234.jpg",
"report": "Expression of xCT mRNA in spleen of the mice injected with a lethal dose of LPS by nonisotopic in situ hybridization. Mice were intraperitoneally injected with saline (A, B) or 160 mg/kg (C, D), and the spleen was isolated after 8 h. Adjacent sections were hybridized with DIG-labeled antisense (A, C) or sense (B, D) probes for xCT. Magnifications: ×50.",
"metadata": {}
},
{
"id": 399,
"image": "PMC2893050_f3_67620.jpg",
"report": "Immunohistochemical staining for CXCR4. Immunoreactivity for CXCR4 was observed in vascular endothelial cells (A: original magnification 100×) and stromal cells (B: original magnification 40×). Double immunohistochemistry for CXCR4 (red) and c-kit (blue). Cells co-expressing CXCR4 and c-kit were observed in the vascular endothelium (arrows) and in close association with blood vessels (arrowheads). C: original magnification 100×.",
"metadata": {}
},
{
"id": 400,
"image": "PMC2875657_F2_64763.jpg",
"report": "CCL2 is stored in cytoplasmic vesicles in fibroblast-like synoviocytes (FLS). FLS were cultured for 24 hours in the absence (a, c) or presence (b) of 50 μg/ml monosodium urate (MSU) crystals. Cells were subjected to immunostaining with anti-CCL2 antibodies (a, b) or incubated with the second antibody only as a negative control (c), and then analyzed with confocal microscopy, as described in Materials and Methods. Original magnification, ×1,000.",
"metadata": {}
},
{
"id": 401,
"image": "PMC2440388_F2_24747.jpg",
"report": "Photomicrograph showing parts of two cysticerci with intervening lymphoid tissue. Hematoxylin and eosin stain, 2× magnification.",
"metadata": {}
},
{
"id": 402,
"image": "PMC2804601_F3_54563.jpg",
"report": "Transmission electron microscopy images of A. baumannii SMAL biofilm-forming cells. Panel A: A. baumannii cells resuspended from biofilm 10,000× magnification. The bundle-like fibers embedding the bacterial cells are indicated by the arrow. Panel B: A. baumannii cells resuspended from biofilm and treated with 1 Unit cellulase for 30 minutes, 12,000× magnification.",
"metadata": {}
},
{
"id": 403,
"image": "PMC2653634_pone-0004845-g005_35787.jpg",
"report": "Photomicrograph of kidney tissue from virgin (left panel) and pregnant (right panel) rats.Representative LGR7 immunostaining (dark brown) in the cortex (A, 200× magnification), the cortex showing the apical membrane distribution of LGR7 in proximal tubules (B, 400× magnification), glomeruli (C, 400× magnification) and the negative control (D, omission of primary antibody, 200× magnification).",
"metadata": {}
},
{
"id": 404,
"image": "PMC3040762_pone-0017193-g002_87530.jpg",
"report": "The representative IHC nuclear CK2α staining corresponding to\nmean nuclear CK2α labeling index values for different\nparameters.Magnification: 400×.",
"metadata": {}
},
{
"id": 405,
"image": "PMC1402319_F2_4862.jpg",
"report": "A higher magnification of the aspirate from same area as shown in Figure 1 shows small to intermediate sized mononuclear cells with moderate cytoplasm, round to oval nuclei with smooth nuclear borders, a stippled chromatin pattern and occasional single nucleoli. The cytoplasm is pale grey and granular with hair-like and short, blunt, cytoplasmic projections. (Stain: Diff Quik, Magnification: × 60).",
"metadata": {}
},
{
"id": 406,
"image": "PMC1564042_F7_7129.jpg",
"report": "Small basement membrane-like material may be present in adenoid basal lesions. (hematoxylin and eosin, original magnification 40×)",
"metadata": {}
},
{
"id": 407,
"image": "PMC3071789_F3_91912.jpg",
"report": "Microscopic lesions. (A) Histopathological examination of diseased pigs showed cortical neuronal edema and increased peripheral space (H&E, 400×; bar = 100 μm). (B) Small glial cells surrounded neurons and exhibited neuronophagia and satellitosis (H&E, 400×; bar = 100 μm).",
"metadata": {}
},
{
"id": 408,
"image": "PMC2966419_pone-0013751-g001_77482.jpg",
"report": "HA-TGF-β1(a) transgenic expression.\nPanel A\n. Representative genomic DNA PCR screen of transgenic litters demonstrating germline transmission. Panel B. RT-PCR for transgene message in the prostate gland. GAPDH amplification serves as an internal control. Panel D. IHC of transgene demonstrates focal expression in ventral, lateral, and dorsolateral regions of secretory acini. Panel C. Wildtype acini demonstrate no immunoreactivity to HA epitope. Images C and D were captured at ×200 magnification.",
"metadata": {}
},
{
"id": 409,
"image": "PMC2871138_f2-ijms-11-01792_64087.jpg",
"report": "Photograph after 90 days of incubation of sample in fungal culture. The fungal growth (≥25%) indicates the biodegradability of the sample 41/Table 8: poly(acetyl methacryloyl sucrose-co-styrene).",
"metadata": {}
},
{
"id": 410,
"image": "PMC2766363_F1_48494.jpg",
"report": "Reactive urothelium (A and B) (hematoxylin eosin, original magnifications × 40 (A), × 200 (B)). Cytoplasmic immunoreactivity in reactive urothelium to CK20 in 1/3 urothelium including umbrella cells (original magnifications × 40 (C), × 200 (D), × 400 (E)).",
"metadata": {}
},
{
"id": 411,
"image": "PMC3080280_F5_92935.jpg",
"report": "CD31 immunohistochemical stain. There are numerous small-sized vessels within the stroma of the cellular blue nevus.",
"metadata": {}
},
{
"id": 412,
"image": "PMC2841668_F2_59731.jpg",
"report": "3D SHG renderings (left panels) and H&E staining (right panels) of normal (top) and malignant ovarian biopsies (bottom). The field size for the 3D renderings was 170 microns and the histology cross sections were captured at 40×.",
"metadata": {}
},
{
"id": 413,
"image": "PMC2737765_F4_44856.jpg",
"report": "Histopathology of skin biopsy (left popliteal area).",
"metadata": {}
},
{
"id": 414,
"image": "PMC2633285_F6_33511.jpg",
"report": "Immunohistochemistry of FANCC and PTCH1 (a-c) FANCC expression pattern (d-f) PTCH1 expression pattern. BC samples showing high (a and d) or moderate (b and e) or low (c and f) expression of FANCC and PTCH1 genes respectively. Arrow (→) indicates the expression pattern of FANCC and PTCH1 in primary BC. All magnifications are at 20×.",
"metadata": {}
},
{
"id": 415,
"image": "PMC2868877_F2_64020.jpg",
"report": "Histology of pulmonary lesions. Hematoxylin and eosin stain was used for the lung biopsy, original magnification, 400×. Arrow points to eosinophils with pink color; alveoli are infiltrated with inflammatory cells, mainly eosinophils, lymphocytes and neutrophils. There is no evidence of vasculitis or alveolar hemorrhage. There is some fibrous tissue in the periphery. Note that only distal airways are involved with sparing of proximal airways.",
"metadata": {}
},
{
"id": 416,
"image": "PMC2823673_F3_57107.jpg",
"report": "Histopathological changes in the lungs of virus challenged mice. Mouse lungs were collected for histopathological analysis 5 days after virus challenge. The figure indicates the representative images of histopathological damage from H&E-stained lungs of mice vaccinated with M2e-MAP plus adjuvant or adjuvant only (magnification, 100×).",
"metadata": {}
},
{
"id": 417,
"image": "PMC2774455_f3_50236.jpg",
"report": "Presence of a \"peculiar\" electron-dense substance in the intraepithelial cysts of the corneal epithelium sampled from the proband. A: Electron micrograph of corneal epithelium depicting an intraepithelial cyst containing a \"peculiar\" electron-dense substance (asterisk) intermixed with small vacuoles and electron-dense filamentous material (original magnification 5,400x). B: Higher magnification of A. The cyst was bordered by numerous microvillous processes (arrowheads).",
"metadata": {}
},
{
"id": 418,
"image": "PMC1559625_F1_6966.jpg",
"report": "Hemophagocytosis in lymph nodes from a patient with HME (left) and RMSF (right) (H&E; original magnification 240×).",
"metadata": {}
},
{
"id": 419,
"image": "PMC1947996_F2_13009.jpg",
"report": "Autoradiograms of the Southern blot analysis of the presence of Rxfp1 and Rxfp2 mRNA in the vas deferens (NW = not washed, W = washed to remove spermatozoa) and in spermatozoa removed from the cauda epididymis. The amount of cDNA used from the vas deferens was 2 μL. Exposure to film was 2 h for Rxfp1 and 1 h for Rxfp2 transcripts. Results are representative of 3 independent determinations, each one with a different animal.",
"metadata": {}
},
{
"id": 420,
"image": "PMC1618402_F4_7521.jpg",
"report": "Cytological examination of the labeled DNA distribution in MCF-7 cells. (a) Several minutes incubation of MCF-7 cells with FITC-labeled fragmented human DNA. The main part of the label is localized to the cytoplasm. (b) 14-h incubation of MCF-7 cells with FITC-labeled fragmented human DNA. The label is concentrated in the nucleus and is undetectable in the cytoplasm.",
"metadata": {}
},
{
"id": 421,
"image": "PMC3073898_F4_92157.jpg",
"report": "Transient co-localization studies of UGT73C6-YFP and BES1-CFP in tobacco. UGT73C6-YFP and BES1-CFP were transiently co-expressed in leaves of Nicotiana benthamiana and localization was examined by fluorescence microscopy. All pictures were taken with the same magnification. The scale bar represents 10 μm.",
"metadata": {}
},
{
"id": 422,
"image": "PMC2228398_fig03_17177.jpg",
"report": "Confocal (a, c) and SEM (b, d) pictures of the biofilm growing on anodes of fuel cells inoculated with Shewanella oneidensis MR-1. Fuel cells were fed with FW medium supplemented with lactate and (a, b) amino acids; (c, d) yeast extract. Anodes for CLSM examination were directly stained with the BacLight Live/Dead kit (Korber et al., 1996). Live cells appear green and dead cells red.",
"metadata": {}
},
{
"id": 423,
"image": "PMC2717141_f1-ehp-117-1131_42394.jpg",
"report": "Cellular composition of human neurospheres shown in cryostat sections (10 μm) of proliferating (A and B) and differentiating (8 days after plating; C and D) neurospheres (representatives of five spheres for each developmental stage). Nuclei are stained in blue with Hoechst; nestin and β(III)tubulin are stained in green; and GFAP is stained in red. Individual antibody stainings are shown as contrast images. Bars = 100 μm.",
"metadata": {}
},
{
"id": 424,
"image": "PMC1941843_F7_12842.jpg",
"report": "Visualization of interaction between DNA and cell membrane. Visualization of interaction between DNA and cell membrane after single polarity electric field protocol (a) and both polarities electric field protocol (b). Photos of phase contrast (1) and fluorescence (2) images were taken under inverted fluorescence microscope. Symbols on the right represent electric field protocol used.",
"metadata": {}
},
{
"id": 425,
"image": "PMC3000094_f6-ijms-11-04465_80727.jpg",
"report": "Photomicrograph showing cells containing ubiquitin-positive inclusions in the rat 6-OHDA-lesioned striatum. Immunohistochemical staining, magnification × 400. Internal scale bar = 25 μm. (A) Saline control (SAL + aCSF); (B) mildronate at 50 mg/kg (M50 + aCSF); (C) 6-OHDA (SAL + 6-OHDA); (D) M50 + 6-OHDA; Arrows indicate cells containing ubiquitin-positive inclusions in the 6-OHDA group.",
"metadata": {}
},
{
"id": 426,
"image": "PMC3014972_F3_83037.jpg",
"report": "PfSHMTm immunofluorescence images showing localization in the mitochondrion. (A) Two late trophozoites. (B-D) Mitotic schizonts. (E) Post-mitotic schizont. The images show the persistence of co-localization of PfSHMTm fluorescence with the mitochondria throughout the developmental cycle (scale bars 3 μm). The associated table shows the percentage volume (V%) and material (M%) co-localization data for PfSHMTm (Sm) and MitoTracker (MIT) fluorescence.",
"metadata": {}
},
{
"id": 427,
"image": "PMC2653470_F2_35660.jpg",
"report": "Atherosclerotic plaque in aortic sinus sections. Both sections are stained with hematoxylin-eosin, and presented at 40× magnification. A) Control group with mild to moderate plaque is present at the base of the valves. B) A-002 group with minimal plaque is present at the base of the valves. The dark arrows demonstrate the foam cells.",
"metadata": {}
},
{
"id": 428,
"image": "PMC2862504_F0004_63305.jpg",
"report": "Representative immunhistochemistry staining of Ki-67, Cyclin-D1, SOX9 and β-catenin of normal colonic mucosa (left side) and adenoma (right side) in mice subjected to the DSS-AOM (Dextran Sulfate Sodium - Azoxymethane) model of carcinogenesis without treatment (control group) (x200 magnification)",
"metadata": {}
},
{
"id": 429,
"image": "PMC2409764_fig1_23781.jpg",
"report": "Pimonidazole staining photographs (made with Carl Zeiss KS100 Software). (A) Peripheral view. (B) Central view. Both slices are shown on a magnification × 25. Scale bar is 40 μm. Abbreviations: N=necrosis, V=viable, well-oxygenated tumour tissue, P=PIMO-positive staining and the arrow indicates a blood vessel.",
"metadata": {}
},
{
"id": 430,
"image": "PMC1592110_F4_7377.jpg",
"report": "Immunohistochemical stainings of gliomas. Glioma cell proliferation was assessed by immunostaining for Ki67 positive glioma cell nuclei (arrows) in rats implanted with gliomas (a) and in rats co-injected with apyrase (b). The sections were immunostained for VEGF, in rats implanted with gliomas (c) and in rats co-injected with apyrase (d). Scale bars = 20 μm (a,b); 100 μm (c,d).",
"metadata": {}
},
{
"id": 431,
"image": "PMC2816359_fig03_56136.jpg",
"report": "RNase A·5′-ATP complex (mol A). Shown in stereo are ball-and-stick representations of the inhibitor and RNase A residues in and around the binding site, along with a surface representation of the enzyme. Main chain N, C, and O atoms of residues K7, Q11, H12, K41, V43, and E111 are omitted for clarity. The coloring scheme is: nucleotide carbon, gold; protein carbon, gray; nitrogen, blue; oxygen, red; phosphorus, pink. Spheres denote water molecules and dashed lines denote hydrogen bonds.",
"metadata": {}
},
{
"id": 432,
"image": "PMC2613076_f2_31906.jpg",
"report": "Trichostatin A suppressed the myofibroblastic differentiation of mouse corneal stromal cells induced by TGFβ1. Corneal fibroblasts treated with 1 ng/ml TGFβ1 for 4–5 days exhibited enhanced staining with FITC-conjugated phalloidin (A), α-SMA (B), and collagen I (C). However, the keratocytes treated with TGFβ1 in the presence of 400 nM TSA remained small with dendritic-like morphology and weak or only minimal staining of phalloidin (D), α-SMA (E), and collagen I (F). Bar, 50 µm.",
"metadata": {}
},
{
"id": 433,
"image": "PMC2868780_F3_63880.jpg",
"report": "Immunohistochemical staining of positive control (G1) tissue using antibody against COX-2. Immunoreactivity was present throughout the epithelial cells (100× magnification) (1). Immunohistochemical staining of G2 tissue using antibody against COX-2 showing weaker staining compared to G1 (100× magnification) (2). Immunohistochemical staining of negative control (G5) tissue using antibody against COX-2 (100× magnification)(3).",
"metadata": {}
},
{
"id": 434,
"image": "PMC2989747_fig5_79350.jpg",
"report": "Acute erosion, with late organization, Movat pentachrome. (a) Low magnification of the left anterior descending coronary artery. The underlying plaque is rich in smooth muscle cells, without significant lipid and no core formation (b) A higher magnification of the nonocclusive eroded thrombus. (c) Multiple layers of fibrin are present in the smooth muscle cell rich cap.",
"metadata": {}
},
{
"id": 435,
"image": "PMC2361490_fig1_21459.jpg",
"report": "Immunohistochemical expression of carcinogenesis factors in SCCO: (A) p53 intense nuclear staining, HESx100, (B) EGFR intense membranous staining, HES × 200, (C) VEGF expression: cytoplasmic staining, more intense in cancer cells (♣) than in smooth muscle cells (▴), HES × 200; (D) HER-2 complete and strong membranous staining, scored ‘3+’, HES × 400; (E) CD117 focal cytoplasmic staining, HES × 200.",
"metadata": {}
},
{
"id": 436,
"image": "PMC2292678_F3_20067.jpg",
"report": "Two sections (A, B) of the nodule. The GS staining allows the distinction between non-nodular tissue and the nodule. The broken line delineates the frontier. Figures 9, 20–25 are from section A. The upper figure is from non-nodular tissue and the lower figure is from the nodular area. Figures 4-6 are from section B (blue rectangle). Figures 7, 8, 10-19 are from the same section (yellow rectangle). The upper and lower microphotographs illustrate the same area (serial sections).",
"metadata": {}
},
{
"id": 437,
"image": "PMC2375978_fig4_22390.jpg",
"report": "(a) Light and fluorescent micrographs of an islet, (b) the same islet labeled with\nAL3-FITC, (c) and the two images superimposed. (d) A hematoxylin and eosin stained\nsection from an NOD mouse (e) and normal CBA/J pancreatic sections (e; 10× magnification).\nNote the presence of islets in the normal pancreas (arrows) and none in the\ndiabetic.",
"metadata": {}
},
{
"id": 438,
"image": "PMC1318477_pbio-0040029-g002_4211.jpg",
"report": "Dendritic Arbors of Pyramidal Neurons Are Stable(A) MZPs near the cell body of the pyramidal cell “dow” acquired over 9 wk.(B) Two-dimensional projections of three-dimensional skeletal reconstructions of “dow.”(C) High-magnification view of branch tip (green arrow) in region outlined by green box in (B).Scale bars: (A and B), 50 μm; (C), 10 μm.",
"metadata": {}
},
{
"id": 439,
"image": "PMC3049733_f2_89045.jpg",
"report": "Pathological findings. A, B: Case 4 frozen tissue section (cornea, hematoxylin & eosin staining, original magnification 40×, 100×). B: Magnified view of boxed area with an arrow in A. Corneal tissue near the perforation. C, D: Frozen tissue section (cornea, hematoxylin & eosin staining, original magnification 100×, 200×) Corneal tissue near the perforation. The epithelium neighboring the corneal ulcer showed partial thinning (arrow).",
"metadata": {}
},
{
"id": 440,
"image": "PMC3080331_F2_92974.jpg",
"report": "p53 immunohistochemical negative staining in a grade 2 ductal carcinoma. The wide majority of nuclei showed no staining with the exception of one clear positive nucleus (arrow) in the upper left corner. Original magnifications: ×100 (inset ×250).",
"metadata": {}
},
{
"id": 441,
"image": "PMC2999444_f02_80672.jpg",
"report": "Wing epidermal cells expressing EGFP after plasmid injection followed by electroporation. A) 3 pulses of 80 V, o.1 ms pulse duration, and 100 ms pulse interval (100X magnification). B) 3 pulses of 80 V, 1 second pulse duration, and 500 ms pulse interval (200X magnification). C) and D) Epidermal cells of wings treated in the same way as in A) and B) but injected with blue colored water.",
"metadata": {}
},
{
"id": 442,
"image": "PMC2958303_fig2_76472.jpg",
"report": "Effects of SP on the expression level of adhesion molecules on HMVEC. (a) The concentration of sICAM1 and sVCAM1 in the conditioned medium derived from SP-treated HMVEC. N = 3. Error bar: SD. (b) Immunolabeling of ICAM1 and P-selectin on HMVEC with various treatments. Magnification, ×200.",
"metadata": {}
},
{
"id": 443,
"image": "PMC1397829_F2_4762.jpg",
"report": "Expression pattern of αVβ3 in juvenile DM, adult DM, and control muscle biopsies. Frozen muscle sections from myositis and normal human muscle control samples were stained with antibodies that recognize αVβ3. Representative staining patterns for αVβ3 in control (panels a&c) and DM (panel b) and juvenile DM (panel d).",
"metadata": {}
},
{
"id": 444,
"image": "PMC2360632_fig4_21305.jpg",
"report": "Invasive breast cancer specimens from the tissue microarray with (A) negative, (B) moderate, and (C) strong positive staining reaction for PRL-3. (D) Strong PLR-3 staining of tumour vessel. (E) PRL-3 negative and (F) positive lymph node metastases. Magnification 10-fold.",
"metadata": {}
},
{
"id": 445,
"image": "PMC2895301_fig2_67956.jpg",
"report": "\nGlomerular hypertrophy and collapse in diabetes were ameliorated by ciglitazone. Histological kidney section were stained with Masson-Trichrome stain and visualized under dissecting microscope. Note that glomerular hypertrophy was observed at one week of alloxan (a single dose of 65 mg/kg body wt intraperitoneally) treatment. At 10 weeks glomerulus was collapsed. Ciglitazone treatment after 10 weeks of alloxan treatment reversed glomerular deformation towards normal (magnification, x200).",
"metadata": {}
},
{
"id": 446,
"image": "PMC2909981_F1_69841.jpg",
"report": "Immunohistochemical staining of HIF-1α, CAIX, Glut-1 and p27kip1 in endometrioid endometrial carcinoma. Typical patterns are shown: A) perinecrotic HIF-1α expression (10× magnification). B) Diffuse HIF-1α expression (10× magnification). C) Diffuse p27kip1 expression (10× magnification). D) Perinecrotic Glut-1 expression (10× magnification) E) Membrane CAIX expression (20× magnification). Asterisk indicates necrosis.",
"metadata": {}
},
{
"id": 447,
"image": "PMC2797365_fig3_53234.jpg",
"report": "(a) Histopathological image of the primary tumor showing moderate cellularity and a rounded, clear cytoplasm. Histological examination of the dura and the nerve roots revealed infiltration by cells of the anaplastic astrocytoma: (b) Hematoxylin-Eosin staining, magnification 250-fold. (c) Elastica-van-Gieson staining showed tumor cells within dural collagen fibers, magnification 500-fold.",
"metadata": {}
},
{
"id": 448,
"image": "PMC2661790_fig3_36656.jpg",
"report": "Tissue-based studies of U87MG human tumours xenografted into NMRI nude mice treated with nimotuzumab (h-R3), or cetuximab (C225), or radiation alone (RT), or both modalities. Immunohistochemical analysis of tumour cells stained with anti-EGFR, anti-Ki-67 nuclear antigen, apoptosis by TUNEL and angiogenesis with anti-CD31 antibody ( × 40 magnification).",
"metadata": {}
},
{
"id": 449,
"image": "PMC3082966_F2_93484.jpg",
"report": "Life history of Conopomorpha flueggella. 5 adult, holotype, male 6 female moth resting on a female flower at night 7 mature larva weaving pupal cocoon on a host leaf 8 pupa 9 pupal cocoon on a host leaf 10 infested fruit.",
"metadata": {}
},
{
"id": 450,
"image": "PMC2376165_fig3_22430.jpg",
"report": "Cell morphology of PANC-1 clones transfected with hyperstable U1snRNA. Parent PANC-1 (A) and transfectants, Pr1A-4 (B), Pr1S (C), Pr3A-4 (D), Pr3A-5 (E), and Pr3S (F) were cultured to confluence and photographed at a magnification of ×200. The r1A and r3A transfected clones are heterogeneous in their cell morphology and contain many multinucleated giant cells.",
"metadata": {}
},
{
"id": 451,
"image": "PMC2886081_F2_66264.jpg",
"report": "Punch biopsy of one papule with central foreign body. Hematoxylin and eosin (H&E)-stained cross-section of one papule. Arrow indicates foreign body. Image captured at 10× magnification.",
"metadata": {}
},
{
"id": 452,
"image": "PMC2235833_F1_17444.jpg",
"report": "Ewing tumor cells overexpressing EGFR. Cells (EWS TC71 and EWS IOR/CAR) were fixed and stained for EGFR using rabbit polyclonal antibodies, which were visualized with goat Cy3-conjugated secondary antibodies. Images show Cy3 fluorescence (left), DAPI staining of nuclei (middle) and merge (right). Images were recorded by laser scanning microscopy. Bars indicate 10 μM.",
"metadata": {}
},
{
"id": 453,
"image": "PMC2570612_pgen-1000240-g005_29150.jpg",
"report": "Nuclear ultrastructure in flo mutants.Transmission electron micrographs of nuclei from representative 5 dpf wild type and flo intestinal epithelial cells. (A,B) Intact nuclear envelope in wild type (A) and flo (B). (C–F) Tangential sections through the nuclear envelope showing abundant nuclear pores (arrows) in the wild type larva (C,E) but few if any well defined pores in the flo larva (D,F). (E) and (F) are higher magnification views of (C) and (D), respectively.",
"metadata": {}
},
{
"id": 454,
"image": "PMC514604_F1_302.jpg",
"report": "CS17 OPT model (a). still shot from movie of 3D OPT model of a CS17 human embryo (approximately 41 days of development). bv, blood vessel; drg, dorsal root ganglion; h, heart; H, hindbrain; l, liver; T, telencephalon; v, vertebrae. (b; Additional file 1) Mpeg movie of 3D CS17 OPT model.",
"metadata": {}
},
{
"id": 455,
"image": "PMC2695862_fig02_39960.jpg",
"report": "Endogenous catecholamine fluorescence in tuberoinfundibular dopaminergic cell bodies and median eminence of Snell dwarf (dw/dw, lower panels) and normal (DW/dw, upper panels) mice treated daily with saline, 5 μg of ovine prolactin (oPRL), 50 μg of oPRL or 50 μg of recombinant mouse prolactin (rmPRL) beginning at 3 days of age. Coronal sections; original objective magnification: × 20. Scale bar = 100 μm.",
"metadata": {}
},
{
"id": 456,
"image": "PMC2962632_pone-0013603-g004_76687.jpg",
"report": "Immunohistochemical controls for LMP1 and EBERs RNA in situ hybridization.\nA) HL case: LMP1 positive staining in the membrane of Reed Stenberg cells and HL mononuclear cell (400X). B) LMP1 negative ductal breast carcinoma (400X). C) EBERs RNA positive staining in HL Reed Stenberg cells (400X). D) EBERs RNA negative ductal breast carcinoma (400X).",
"metadata": {}
},
{
"id": 457,
"image": "PMC2807460_pone-0008749-g002_55027.jpg",
"report": "Representative pancreatic islets showing insulin staining (brown) in untreated STZ-diabetic mice, non-diabetic control and STZ-diabetic mice treated with insulin implants or islet transplant (txp) under the kidney capsule for 60 or 120 days (40x).",
"metadata": {}
},
{
"id": 458,
"image": "PMC2743993_pone-0007184-g001_46024.jpg",
"report": "Spr1-GFP is a marker for spore wall permeability.AN120 (wild-type), AN262 (chs3Δ), and AN264 (dit1Δ) harboring high copy plasmids expressing SPR1-GFP or ssGFP (pRS424-SPR1-GFP or pRS424-ssGFP) were examined by fluorescence microscopy 8 hours or 20 hours after transfer to sporulation medium. Arrows indicate asci displaying fluorescence in the ascal cytoplasm. Bar = 5 µm.",
"metadata": {}
},
{
"id": 459,
"image": "PMC3080389_pone-0018877-g004_93046.jpg",
"report": "Invasion of CHO cells.A.) S. elongatus engineered with invasin and listeriolysin are able to invade CHO cells at a higher efficiency than S. elongatus harboring the empty vector or invasin alone. Cells positive for red fluorescence were sorted by FACS and B.) observed under confocal microscopy, showing intracellular localization of at least one bacterial cell per CHO cell in the majority of the cells observed.",
"metadata": {}
},
{
"id": 460,
"image": "PMC2376369_fig1_22465.jpg",
"report": "Expression of CA XII in invasive breast tumours. The panels show representative examples of CA XII expression detected by IHC in three invasive ductal carcinomas. The cases were associated with overall IHC scores of 10 (A and B), 100 (C and D), and 225 (E and F) respectively. Panels on the right side (B, D and F) are higher magnifications to show cellular detail within the corresponding tumour shown on the left. Original magnifications; left × 40, right × 200.",
"metadata": {}
},
{
"id": 461,
"image": "PMC2613893_F2_32087.jpg",
"report": "Subepidermal bullae. Dermis shows perivascular inflammatory infiltrates containing eosinophils and neutrophils (HE, original magnification ×100).",
"metadata": {}
},
{
"id": 462,
"image": "PMC3046254_pone-0017526-g006_88602.jpg",
"report": "Expression of candidate mechanosensitive genes in control and immobilised specimens on longitudinal sections through the knee joint.Images A’–D’ (scale bar 0.1 mm) show the knee region of A to D (scale bar 0.5 mm) at a higher magnification. cc; capsular condensation, cl; chondrogenous layer, iz; intermediate layer, jf; joint fusion, m; meniscus, p; patella, par; periarticular cartilage, t; tendon, tc; tibial crest.",
"metadata": {}
},
{
"id": 463,
"image": "PMC2664462_pone-0005142-g002_36882.jpg",
"report": "Flagellar stains of wild type and mutant strains.Some flagella are indicated by arrows. Shown are representative panels from the three different strain backgrounds: Row A) 10403 strain background, Row B) RM2387 strain background, Row C) RM2992 strain background. All micrographs were taken at 1000× magnification.",
"metadata": {}
},
{
"id": 464,
"image": "PMC2266934_F1_18837.jpg",
"report": "Reflectance confocal microscopy (RCM) can visualize ductal epithelial cells during mammary gland development, growth, and aging. Prominent features distinguishable with RCM are (A-B) rudimentary primary ductal trees (open arrowheads), (C-D) terminal end buds (closed arrowheads), (E-I, P) secondary branching (thin arrows), (J-M) tertiary branching (open arrows), (N-O) lobules (thick arrows), (Q) ductal ectasia or enlarged ducts (^). Magnification: 30×.",
"metadata": {}
},
{
"id": 465,
"image": "PMC1276786_F5_3727.jpg",
"report": "Plots of the tail of the global alignment optimal score distribution. The score frequencies were plotted against the natural logarithm of scores at the tail of the distribution of Figure 1. The three theoretical distributions were indicated in solid lines. The score distribution was fitted with (A) the three-parameter gamma distribution; (B) the normal distribution; and (C) the Gumbel distribution.",
"metadata": {}
},
{
"id": 466,
"image": "PMC2987765_F2_78763.jpg",
"report": "Localization of Ack1 proteins. Cos7 cells co-expressing wild-type or mutant HA-tagged Ack1 along with a membrane targeted form of GFP (PM-GFP) [40] were prepared for immunostaining and confocal microscopy as described in Materials and Methods. Ack1 proteins were detected with anti-HA antibodies. Anti-HA; left panels; PM-GFP, middle panels; merged images, right panels. Scale bar: 10 microns.",
"metadata": {}
},
{
"id": 467,
"image": "PMC2500017_F1_26347.jpg",
"report": "FRAP of GFP-tagged Nrg in epithelial cells of live embryos. Side views of epithelial cells in wild-type (A), nrx IV (B), cont (C) and Dfvari (D) embryos at stage15. Pre-bleach images are shown on the left. The sections of cell interface that were bleached are indicated with boxes. Images on the right show the recovery of fluorescence 160 seconds after bleaching. Bar: 5 μm. Schematic representation of the distribution of septate junction components, Nrg, Nrx IV and Cont in each genotype.",
"metadata": {}
},
{
"id": 468,
"image": "PMC2360358_fig6_21193.jpg",
"report": "Cytopathology of T98G cells exposed to vehicle or 17α-AED (10 μM) for 30 h. (A) T98G cultures treated with vehicle are composed of cells with epithelioid morphology; a large, pale staining nucleus with prominent nucleoli. A T98G cell undergoing mitosis (M). (B, C) Numerous cells in the 17α-AED-treated cultures show the presence of multiple cytoplasmic vacuoles (arrows) and small, basophilic bodies (arrow heads). Haematoxylin and eosin staining, × 100 magnification with oil.",
"metadata": {}
},
{
"id": 469,
"image": "PMC2887402_F3_66488.jpg",
"report": "Microscopic findings of the colon mass and retroperitoneal masses. Proliferation of atypical spindle or stellate cells(A) focally supported by rich arborizing vasculature on the background of rich ground substance(B) with rare lipoblasts(C), tumor cells extend from the subserosa upward to the submucosa(D), most of tumor consists of mature fat cell-like cells and a few atypical spindle cells or lipoblasts(E). (A, B & E: H-E, ×100, C: H-E, ×400, D: H-E, ×12.5).",
"metadata": {}
},
{
"id": 470,
"image": "PMC2993484_F0002_79841.jpg",
"report": "Map of the Czech Republic and location of sampling sites and the control site.",
"metadata": {}
},
{
"id": 471,
"image": "PMC2715381_F1_42152.jpg",
"report": "The expression of CD133 in colon cancer patients with stage IIIB (10 × 20~10 × 100). The expression of CD133 was examined with immunohistochemical assay. (A): <5% CD133+ cells in the cancer nest; (B): ≥5% CD133+ cells in the cancer nest; (C) and (D): the staining of CD133 on the luminal surface and the basal surface of cancer cells; (E): the staining of CD133 on budding cancer nest; (F): the staining of CD133 on poor-differentiated cancer nests with ductal structures.",
"metadata": {}
},
{
"id": 472,
"image": "PMC2918599_F3_70974.jpg",
"report": "Hydrophobic dorsal surface of Physasterna cribripes. An example of a P. cribripes treated with Sudan III staining in order to examine if the beetles have hydrophilic zones that could facilitate the collection of water from fog. The Sudan III staining make wax covered i.e. hydrophobic areas shiny. The magnification shows the shining hydrophobic peaks of the bumps on the elytra.",
"metadata": {}
},
{
"id": 473,
"image": "PMC2885878_F0003_66173.jpg",
"report": "Immunohistochemistry on the biopsy tissue showing cytoplasmic positivity with HMB-45.",
"metadata": {}
},
{
"id": 474,
"image": "PMC2754611_pone-0007385-g005_47193.jpg",
"report": "Analyzing the effect of DX expression on cell morphology.Phase-contrast micrograph images taken between 2 and 9 hours post-induction show the filamentous phenotype in cells expressing protein DX. The unbiquitin and empty control strains appear normal at all times of induced growth. Images were acquired at 40× magnification.",
"metadata": {}
},
{
"id": 475,
"image": "PMC2822860_pone-0009273-g004_56957.jpg",
"report": "Cellular localization of GFP-fused XtCRYs in HEK 293 cells.Each expression vector was transfected and observed using a fluorescence microscope (upper, GFP; middle, DAPI) or differential interference microscope (lower, DIC).",
"metadata": {}
},
{
"id": 476,
"image": "PMC2900228_F1_68336.jpg",
"report": "Apodemus sylvaticus ES cell and embryoid body. Phase-contrast images of Apodemus sylvaticus ES cell colonies (A) and embryoid bodies after 7 days of formation (B). Scale bar, 100 μm.",
"metadata": {}
},
{
"id": 477,
"image": "PMC2814865_pntd-0000593-g001_55967.jpg",
"report": "Fluorescent labeled short interfering RNA enters cultured eggs of Schistosoma mansoni.Representative images of schistosome eggs and miracidia 24 hours after soaking in Cy3-siRNA; bright field, upper panels, fluorescence, lower panels. Eggs were soaked in medium containing 50 ng/µl of Cy3-siRNA. No Cy3-siRNA treatment control (A, B), Cy3-siRNA treated, fluorescent eggs (C, D) and fluorescent eggs and a miracidium/sporocyst (arrow in E, F). Scale bar, 50µm.",
"metadata": {}
},
{
"id": 478,
"image": "PMC2527015_F12_27108.jpg",
"report": "Representative immunohistochemical expression features of phospho-eIF2α, eIF2α, and BiP proteins in different human lung lesions. The proteins assessed by immunohistochemistry are designated in rows, while the columns depict expression in normal lung tissues, representative positive (ISI values of > 6–9) and negative NSCLCs, and representative positive (ISI values of > 6–9) and negative Small Cell Carcinomas. Magnification, ×200.",
"metadata": {}
},
{
"id": 479,
"image": "PMC2759966_F2_47776.jpg",
"report": "Immunohistochemical detection of Topo I in TMA cores of colorectal carcinoma cases. Strong nuclear staining, graded as positive with a total score of 6/6 (a); moderate, diffused, predominantly cytoplasmic staining, graded as positive with a total score of 5/6 (b); mild focal nuclear and cytoplasmic staining, graded as low expression/negative with a total score of 2/6 (c). (Magnification: ×100).",
"metadata": {}
},
{
"id": 480,
"image": "PMC1559596_F2_6950.jpg",
"report": "Representative pictures of immunostained Aβ plaques (stained with anti-Aβ antibody) in the neocortex of (A) a 15-month-old APP/IL-1 R1+/- mouse; (B) a 15-month-old APP/IL-1 R1-/- mouse; and (C) a 15-month-old wild type Tg2576 mice (IL_1 R1+/+). (A, B, C, magnification = 100×, insert shows enlargement of Aβ plaques).",
"metadata": {}
},
{
"id": 481,
"image": "PMC2556324_F1_28223.jpg",
"report": "Morphology and immunostaining of mouse chondrocytes embedded in agarose gel. A) Chondrocytes cultured in 3D maintain their round morphology. Signs of cell division are observed. B) Pericellular staining with an anti-type II collagen antibody (image captured at the centre of the gel).",
"metadata": {}
},
{
"id": 482,
"image": "PMC2975415_F2_78132.jpg",
"report": "3D location of acetylability related lysine groups. The view angles are labeled as A, B and C. The balls in yellow represent the acetylable lysine, while red for the un-acetylable in training set. The wired ellipsoids are 3D regions related to acetylability. The lysine only and whole nucleosome parts are contained in all three views. An additional surface colored by electronically potential is added to C on the right side.",
"metadata": {}
},
{
"id": 483,
"image": "PMC2700491_F0005_40557.jpg",
"report": "Fine needle aspiration cytology image. (MGG stain, ×100)",
"metadata": {}
},
{
"id": 484,
"image": "PMC2254392_F5_18153.jpg",
"report": "Images from confocal microscopy. Three views of a CF11 fibre are shown, as schematized in the right insertion of figure c. The insertions d, e and f correspond to the pixels intensity (256 grey levels) obtained at the position indicated by the line (white circle), at different depths. The adsorption conditions were 20 mgCBD/gFibre, for 30 minutes of contact. Each image corresponds to an acquisition thickness of 1 μm.",
"metadata": {}
},
{
"id": 485,
"image": "PMC2653772_fig1_35840.jpg",
"report": "Representative images showing expression of RUNX3 in the nucleus only (A), in the cytoplasm only (B) and in both the nucleus and cytoplasm (C). Images are at × 40 magnification.",
"metadata": {}
},
{
"id": 486,
"image": "PMC2690591_F2_39502.jpg",
"report": "Plaque phenotypes of parental virus strains and hybrid virus progenies in IEC-6 cells. Confluent IEC-6 cells were infected with the respective viruses and the HA expression was monitored at 36 hpi by immunoperoxidase staining of fixed cells. The panels show representative fields at approximately × 200 magnification. CPXV-NOHI (A), MVA-HANP (B), Rec 1(C), Rec 2 (D), Rec 3 (E), Rec 3a (F), Rec 3b (G).",
"metadata": {}
},
{
"id": 487,
"image": "PMC1201157_F5_3047.jpg",
"report": "Inhibition of bFGF and VEGF induced capillary morphogenesis of ECs in 3D type I collagen matrix. The samples shown in the upper panels (A-E) were treated with anti-MHC class II mAbs, whereas those in the lower panels (F-J) with anti-αvβ3 integrin antibodies. Cross sections were stained with acidified eosin as described in methods. Magnification, 100×. Bar, 200 μM.",
"metadata": {}
},
{
"id": 488,
"image": "PMC2887531_F0003_66629.jpg",
"report": "Biopsy from the elbow showing acanthosis hyperkeratosis and several burrows showing mites. (H & E Stain, ×40)",
"metadata": {}
},
{
"id": 489,
"image": "PMC1420290_F9_4938.jpg",
"report": "Distribution of FITC-labelled asODN in the mouse nose in vivo. FITC-labelled asODN (80 μg/mouse) were complexed with GL67 and perfused into the nasal cavity. Twenty-four hours later the nasal septum was extracted, paraffin-embedded and processed for confocal microscopy. Nuclei are shown in blue, FITC signal is shown in green. Arrows indicate the surface epithelium. A and B are images from two different animals showing the highest (A) and lowest (B) levels of uptake seen.",
"metadata": {}
},
{
"id": 490,
"image": "PMC2850337_F1_61294.jpg",
"report": "Immunohistochemical detection of survivin. Detection of survivin in leiomyosarcoma in cytoplasm (A) and in cytoplasm+nuclei (B) Detection of survivin in synovial sarcoma in cytoplasm (C) and in cytoplasm+nuclei (D) (magnification 200×)",
"metadata": {}
},
{
"id": 491,
"image": "PMC3065884_fig11_91287.jpg",
"report": "Confocal laser microscopic images for distribution of RH-AF-liposomes and Alexa-pDNA in HepG2 cells. Magnification: ×200. The charge ratio of AF-liposomes/pDNA was 1.6. γ-CyDs were added to AF-liposomes suspension before freeze-drying. The concentrations of γ-CyDs were 1 μM/μM lipids. Cells were incubated with Alexa-pDNA/γ-CyDs/RH-AF-liposomes for 3 h in FCS-free medium. After washing twice, the cells were observed using a confocal laser scanning microscopy.",
"metadata": {}
},
{
"id": 492,
"image": "PMC2376774_fig1_22475.jpg",
"report": "TRAIL is a potent inducer of apoptosis in Jurkat cells. Jurkat T lymphoma cells (0.5×106 ml−1) were exposed to the vehicle (A–C) or 40 ng ml−1 rhTRAIL (D–F), processed for TEM, observed, and images taken at the following magnifications: A, D–1800×; B–5000×; C, F–18 000×; and E–7000×; M-mitotic cell; I–cell in the interphase; Mi–mitochondrium; Nu–nucleolus; V–vacuole; *apoptotic cell; **nucleus with condensed chromatin.",
"metadata": {}
},
{
"id": 493,
"image": "PMC538753_F2_868.jpg",
"report": "Transient expression of GFP and GFP fusion proteins in BY-2 tobacco cells. (A) GFP protein [35SΩ-sGFP (S65T)]; (B) Arabidopsis chloroplast targeting signal (pt)-GFP fusion protein [35SΩ-pt-sGFP (S65T)]; (C) putative localization signal of GGPP synthase-GFP fusion protein [35SΩ-GGPP synthase-sGFP (S65T)]",
"metadata": {}
},
{
"id": 494,
"image": "PMC1538593_F1_6458.jpg",
"report": "LAM5γ2 and HSP27 expression in FF of UIP biopsies. Expression of LAM5γ2 (a, b, and c) and HSP27 (d, and e) in different cases of IPF/UIP. The immunoreactivity is similar for the two molecules, mainly restricted to basal cell sheets located between luminal bronchiolar cells and myofibroblast clusters of fibroblast foci (sandwich-FF).",
"metadata": {}
},
{
"id": 495,
"image": "PMC1675997_F4_7877.jpg",
"report": "Control group, day 45. Surgical cavity (SC) with mature bone tissue, blood vessels and areas of internal remodelling. Fibrous capsules (FC) can be observed on the upper and lateral regions of the slide (HE 40×).",
"metadata": {}
},
{
"id": 496,
"image": "PMC2937225_fig7_73380.jpg",
"report": "Expression and distribution of TRPC6 in ciGEnC and ciPod compared to a platelet positive control. Lysates from ciPod and cGEnC were Western blotted and probed using anti-TRPC6 and anti-actin antibodies. (A) Representative images of ciGEnC (Bi) and ciPod (Bii) were microinjected with pcDNA3TRPC6 and immunofluorescence was carried out using an anti-TRPC6 antibody. Cells were imaged using confocal microscopy. X–Y stacks of ciGEnC and ciPod in (B) are shown in (Ci) and (Cii) respectively.",
"metadata": {}
},
{
"id": 497,
"image": "PMC3073981_pone-0018702-g001_92202.jpg",
"report": "Expression patterns of zebrafish ptenb.(A) Expression of ptenb at designated developmental stage was examined by RT-PCR analysis of an 1183-bp ptenb fragment, and a 530-bp β-actin fragment was used as an internal control. hpf: h post fertilization. (B) Representative photographs of embryos fixed at designated stages and underwent whole-mount in situ hybridization against ptenb. Scale bar: 200 µm.",
"metadata": {}
},
{
"id": 498,
"image": "PMC212693_pbio-0000014-g001_11.jpg",
"report": "FRAP of HP1–GFP Reveals a Dynamic Association with HeterochromatinA fraction of a heterochromatic cluster (arrowhead) was bleached by a laser pulse, and recovery of fluorescence was monitored by time-lapse imaging. Images were kindly provided by Thierry Cheutin and Tom Misteli.",
"metadata": {}
},
{
"id": 499,
"image": "PMC2822859_pone-0009262-g003_56947.jpg",
"report": "XA21 Is Mainly Localized to the Endoplasmic Reticulum in Rice Leaf Sheath Tissue.\nIn planta subcellular localization of Nat XA21-YFP (top) and non-transgenic Kitaake (bottom) were determined using confocal microscopy. Intact adaxial sheath epidermal cells were imaged with an Olympus FV1000 confocal microscope equipped with a 60×oil immersion lens [numerical aperture, 1.42]. YFP signal was excited at 515 nm and emission was collected between 530-560 nm. Scale bar, 5 µm.",
"metadata": {}
},
{
"id": 500,
"image": "PMC1851383_F3_10340.jpg",
"report": "Representative immunohistochemical staining patterns for E-cad, c-met, and Sdc1 in DCIS. Examples for presence (positive) and absence (negative) of marker expression are shown. DCIS, ductal carcinoma in situ; E-cad, E-cadherin; Sdc, syndecan.",
"metadata": {}
},
{
"id": 501,
"image": "PMC2657125_F6_36189.jpg",
"report": "Toxicity observation I. H & E staining of heart(a), liver(b), lung (c), spleen(d) and kidney(e) in recipient mice. No hemorrhage in organs appeared in the combination group and no differences were seen among groups. A: Ad-hEndo+ cisplatin; B: Ad-hEndo; C: cisplatin; D: Ad-null; E: NS.",
"metadata": {}
},
{
"id": 502,
"image": "PMC2770062_F5_49606.jpg",
"report": "Electron microscopy and immunogold labelling of Hsp and Omp50. Immunoelectron microscopic analyses of OMVs. (A) OMVs of wild type C. jejuni strain 81-176 without antiserum (control). (B), immunolabelling with anti-Hsp antiserum. (C) immunolabelling with anti-Omp50 antiserum. White arrows show the GroEL like particles (in A) and the localization of gold particles on the GroEL like particles (in B). Black arrows show the OMVs (in A&B). Bars correspond to 100 nm.",
"metadata": {}
},
{
"id": 503,
"image": "PMC3034992_fig2_86541.jpg",
"report": "Langerhans cells with moderate to abundant cytoplasm and prominent nuclear grooves (Papanicolaou stain, original magnification, ×400).",
"metadata": {}
},
{
"id": 504,
"image": "PMC2908095_F7_69441.jpg",
"report": "Immunohistochemical examination of NPC and normal nasopharyngeal epithelium (Normal NP) specimens for LMP1, Id1 and Foxo3a expression. Intensive nuclear staining for Foxo3a was observed in normal NP epithelium with weak expression of Id1. In NPC tumour T1 which expresses high level of LMP1, strong Id1 expression and weak nuclear staining of Foxo3a was observed. In NPC tumour T3 which shows weak LMP1 expression, strong nuclear staining of Foxo3a and weak Id1 detection was observed.",
"metadata": {}
},
{
"id": 505,
"image": "PMC1697812_F6_7909.jpg",
"report": "Receptor-free uPA is required for fibrin clearance. Detection of fibrin deposition by immunohistochemistry (red stain, arrows) shows uniform staining in centrilobular area in livers of mice of all genotypes 2 days after CCl4. The clearance of fibrin coincides with the resolution of the centrilobular injury by day 14 in mice of each genotype, except for uPA° mice. (Magnification 200×)",
"metadata": {}
},
{
"id": 506,
"image": "PMC2075367_pone-0001202-g004_14829.jpg",
"report": "Expression of BCAS3 in embryoid bodies at day 14 of differentiation.Human EBs at day 14 of differentiation immunostained for (A, E, I, M) BCAS3 (green), (Q) isotype control (green), (B) PECAM (red) and (F, J, N, R) ICAM2 (red). (C, G, K, O, S) show nuclei stained with DAPI. (D, H, L, P, T) are merged images of respective panels to their left. Boxed area in (E–H) imaged at higher magnification shown in (I–L) respectively. Scale bar: (A, M, Q) 50 µm (E, I) 100 µm.",
"metadata": {}
},
{
"id": 507,
"image": "PMC2731731_F2_44220.jpg",
"report": "Immunohistochemical examination of CDH1 protein expression in sporadic gastric cancers. Representative gastric cancer samples are shown. (A) and (C), sporadic gastric cancer showing CDH1 protein expression; (B) and (D), sporadic gastric cancer not showing CDH1 expression. (A) and (B), H-E stained; (C) and (D), immunostained for CDH1. Scale bar, 50 μm.",
"metadata": {}
},
{
"id": 508,
"image": "PMC2773734_f3_50055.jpg",
"report": "Chromogenic in situ hybridization for chromosome 18 and 8q22 amplification in breast carcinoma. A: Invasive melanoma, hybridized with chromosome 18 showing two copies in all the cells. B: Non-metastasizing melanoma hybridized with chromosome 18 showing two copies in most of the cells. C: Normal retina hybridized with chromosome 18 showing two copies in all the cells. D: Breast carcinoma hybridized with chromosome 8q22 showing positive amplification (large cluster).",
"metadata": {}
},
{
"id": 509,
"image": "PMC3062565_pone-0018049-g003_90789.jpg",
"report": "The effect of FTS on muscle pathology.Digital images of hematoxylin and eosin stained muscle. (A) WT untreated mouse presenting normal organization of muscle tissue with no abundant connective tissue. (B) Untreated dy2J/dy2J mouse showing severe dystrophic changes with abnormal variation of fiber size, internal nuclei and severe fibrosis. (C) Treated dy2J/dy2J mouse, showing still variation in fiber size. Magnification ×400.",
"metadata": {}
},
{
"id": 510,
"image": "PMC1949822_F4_13065.jpg",
"report": "Cell and biofilm morphology of Salmonella Typhimurium UMR1 (wt) and its mutants MAE52 (csgD++), MAE51 (csgD), MAE14 (csgBA), MAE222 (bcsA) and MAE619 (bapA) after growth for 24 hours. The first column shows light microscope (LM) images (with a frame width of approx. 0.6 mm) before drying, the second column light microscope images at the same magnification after drying. The third and fourth columns show AFM images at two different scan sizes.",
"metadata": {}
},
{
"id": 511,
"image": "PMC2895875_F0003_68031.jpg",
"report": "A case of LCNEC in EBUS FNA. a, b) The cytomorphology shows loosely cohesive clusters of cells with nuclear molding, hyperchromasia, and crush artifact, which mimics a small cell carcinoma (a. DQ stain, ×400). However, there are also cells with more abundant cytoplasm and prominent nucleoli (b. DQ stain, ×600). c,d) The cell block showed areas of necrosis and highlights the eosinophilic cytoplasm of the tumor cells, which is most consistent with a LCNEC [(H and E stain, ×400 (C) and ×600 (D)]",
"metadata": {}
},
{
"id": 512,
"image": "PMC2923150_pone-0012142-g005_71392.jpg",
"report": "Biofilm formation in the Δppk2 mutant.(A) The Δppk2 mutant shows enhanced biofilm formation. Biofilm formation as assessed by crystal violet staining. (B) Quantification of biofilm using DMSO. The amount of biofilm formed was dissolved in 1 ml DMSO for 48 h and quantified by measuring absorbance at 570 nm. Each bar represents the mean±SE of 3 independent experiments. ** P≤0.01.",
"metadata": {}
},
{
"id": 513,
"image": "PMC3014814_f04_82917.jpg",
"report": "Comparison of morphology of UV and H2O2 treated Bombyx mori cells. The numbers at the top of the panels show the time stage of the B. mori cell culture after-stimulation. The black arrow indicates typical morphology of the cell in the relevant stage. (A) shows normal B. mori cells. (B–D) show UV treated cells. (E–G) show H2O2 treated cells. The photos were taken at 200× magnification. High quality figures are available online.",
"metadata": {}
},
{
"id": 514,
"image": "PMC2841166_F6_59581.jpg",
"report": "Immunoperoxidase staining of USC-HN1 cells in Nude mouse heterotransplant and in cytospin preparations for HNSCC classification markers. Photomicrograph of immunoperoxidase staining of original tumor biopsy (top), IHC stained formalin-fixed paraffin-embedded tissue sections of USC-HN1 Nude mouse heterotransplant (middle), and USC-HN1 cells from culture in a cytospin preparation (bottom) for keratin, E-cadherin, EGFr, CD44, p53 and Rb (×200 original magnification).",
"metadata": {}
},
{
"id": 515,
"image": "PMC3037350_ppat-1001276-g003_86781.jpg",
"report": "TgRON2 exposes at least one segment on the cytosolic side of the host cell plasma membrane.HFF cells were pre-loaded with antibodies directed against TgRON2-4 and were pulse-infected for 2.5 min, followed by IFA. The upper images show a progressing invasion while the lower images show a terminating invasion, in both cases the arrowhead indicates the MJ and magnifications are shown on the right. Scale bar = 5µm.",
"metadata": {}
},
{
"id": 516,
"image": "PMC3040189_pone-0017026-g005_87433.jpg",
"report": "Cut-marks and percussion marks on facial bones from Gough's Cave.(A) Cut-marks and percussion marks on facial bones from Gough's Cave [GC 87(25), GC 87(29) and GC 87(87)] (scale = 10 mm). (a–g), Alicona 3D images of human modifications (scale = 1 mm). (B), photograph of percussion marks on the inferior labial border of the right central incisor (scale = 5 mm).",
"metadata": {}
},
{
"id": 517,
"image": "PMC2876702_F0003_64897.jpg",
"report": "Photomicrograph (H and E, ×10 and ×20) of computed tomography-guided fine-needle aspiration cytology of the tumor showing cohesive clusters of tumor cells. Inset reveals vacuolated cytoplasm of tumor cells",
"metadata": {}
},
{
"id": 518,
"image": "PMC2876921_F0002_64959.jpg",
"report": "Microscopy of Calotropis procera leaf",
"metadata": {}
},
{
"id": 519,
"image": "PMC2212569_F2_16561.jpg",
"report": "Renal histopathology in knockout MRL mice and control MRL mice. Sections showing the renal histopathology of C4bp-/-MRL/lpr(KO MRL) mice and littermate control (CTRL MRL) mice. (a) Representative formalin-fixed sections from the kidney stained with periodic acid Schiff (0.75NA, 400× magnification). Glomeruli with crescentic changes are shown. (b) Sections stained with periodic acid Schiff showing perivascular inflammation around branching arteries (white arrows) (0.15NA, 50× magnification).",
"metadata": {}
},
{
"id": 520,
"image": "PMC2673047_pgen-1000476-g003_37766.jpg",
"report": "In situ hybridization analyses of genes upregulated in the P0/P1.Transcripts for six genes identified in SAM microarray analyses as differentially expressed in the P0/P1 SAM all accumulate in young leaf primordia (arrows) and in the lower SAM periphery and P0 (arrowhead).",
"metadata": {}
},
{
"id": 521,
"image": "PMC2664464_pone-0005177-g003_36887.jpg",
"report": "Fluorescence microscopic analyses of S. macrospora wild type strains expressing cas1-egfp or cas3-egfp.The images illustrate the fluorescence of CAS1-EGFP and CAS3-EGFP caused by the transformation of plasmids pGFP-CAS1 or pGFP-CAS3, respectively. Transformants were analyzed after growth for two days on solid SWG medium supplemented with hygromycin. DIC: differential interference contrast. Scale bar indicates 20 µm.",
"metadata": {}
},
{
"id": 522,
"image": "PMC2848551_pgen-1000896-g003_60938.jpg",
"report": "Verification of IRS RNAi in peripheral fat body by whole-mount in situ hybridization.Expression of IRS was confirmed in fat body, and staining intensity (purple/red color) was reduced in IRS knockdowns compared to controls. (A,B) High pollen-hoarding strain; (C,D) low pollen-hoarding strain; (E,F) wild type. The honey bee fat body is a single cell-layer primary composed of trophocytes (T) and oenocytes (O). IRS transcript was localized to both cell types. Magnification: 200×.",
"metadata": {}
},
{
"id": 523,
"image": "PMC2919381_pone-0012034-g004_70998.jpg",
"report": "Enlarged glomeruli in seven month old db/db mice.Panels A and C are controls, and panels B and D are from db/db mice. Panels A and B are lower magnification views showing multiple glomeruli, while panels C and D are higher magnification, more clearly showing the size difference. Sections were hematoxylin and eosin stained.",
"metadata": {}
},
{
"id": 524,
"image": "PMC2686684_F3_39105.jpg",
"report": "Expression of Neil3 in developing mouse forebrain. In situ hybridisation was performed on coronal sections of mouse brains at different embryonic stages. Magnifications of Neil3-positive cells are shown to the right. Abbreviations: CA, hippocampal differentiation fields; Ctx, cortex; DG, dentate gyrus; Hy, hypothalamus; LV, lateral ventricle; SM, secondary matrix; SVZ, subventricle zone.",
"metadata": {}
},
{
"id": 525,
"image": "PMC1392236_f5-ehp0114-000412_4732.jpg",
"report": "PMNL identification in the spinotrapezius muscle microcirculation of PM-exposed rats 24 hr after IT exposure. (A) Representative H&E-stained section from a saline-treated rat. Abbreviations: CT, connective tissue; SM, skeletal muscle fiber. (B) Representative H&E-stained section from a rat exposed to 0.1 mg ROFA. Note the deeply lobed nuclei that are characteristic of PMNLs. Bars = 25 μm; similar results were obtained with TiO2.",
"metadata": {}
},
{
"id": 526,
"image": "PMC2978706_pone-0013954-g002_78287.jpg",
"report": "Abrogation of pRb expression disrupts adherens junctions.Immunocytochemical localization of β-catenin in MC3T3 (top) and primary osteoblasts (bottom). pRb-expressing osteoblasts show strong β-catenin membrane-associated labeling along areas of cell-to-cell contact (left) while pRb-deficient osteoblasts show a weak and diffuse labeling, without any clearly discernible membrane labeling (right). Magnification = ×100. Bar = 1 µm.",
"metadata": {}
},
{
"id": 527,
"image": "PMC2938427_fig1_73424.jpg",
"report": "Digital subtraction angiography confirmed an aneurysm at the distal part of right axillary artery (a). In the presented case, pathologic examination of aneurismal sac revealed that all three layers of the arterial wall were intact despite various degrees of degeneration and fibrosis in the media layer (b). H&Ex100.",
"metadata": {}
},
{
"id": 528,
"image": "PMC2843668_F2_60016.jpg",
"report": "Immunohistochemical expression of EIF2C1, EIF2C2, EIF2C3 and EIF2C4 in colon cancer and adjacent non-cancer tissue. In colon cancer tissue EIF2C1-4 expression was often stronger in the cytoplasm compared with adjacent non-cancer tissue (A, B, C, D). Adjacent non-cancer tissue is detected with very weak EIF2C1-4 expression in the cytoplasm (E, F, G, H). Magnifications: ×200.",
"metadata": {}
},
{
"id": 529,
"image": "PMC3003526_F5_81488.jpg",
"report": "Positive localization of matrix metalloproteinase 28 in the inner annulus. Positive localization of matrix metalloproteinase 28 within the pericellular encapsulation matrix (arrows) of cells in the inner annulus of a Thompson Grade II disc. Magnification: ×465.",
"metadata": {}
},
{
"id": 530,
"image": "PMC2848861_pone-0010011-g004_61151.jpg",
"report": "Time-lapse luminescence imaging of the nucleocytoplasmic shuttling of ELuc::importin α in NIH3T3 cells.The expression plasmid carrying ELuc::importin α was transiently transfected into NIH3T3 cells. Images were acquired after 3 h of transfection using 3 min of exposure time at intervals of 4 min with a 40× objective lens without binning. Numbers indicate minutes. A schematic drawing of the expression plasmid is shown on the upper panel.",
"metadata": {}
},
{
"id": 531,
"image": "PMC1325242_F1_4299.jpg",
"report": "Immunohistochemical localization of phospho-Akt in human bronchial biopsies. Sections from human bronchial biopsies were incubated with antibodies specific for the phosphorylated form (ser473) of Akt, color developed with nickel-DAB (black) and counterstained with nuclear fast red. Representative stains of normal (A), mild dysplasia (B), moderate dysplasia (C) and severe dysplasia (D).",
"metadata": {}
},
{
"id": 532,
"image": "PMC2743995_pone-0007156-g001_46031.jpg",
"report": "Localization of actin in Giardia lamblia trophozoites and cysts.The cells were labeled using TRITC-phalloidin and analyzed by confocal microscopy. A, DIC image of trophozoites. B, Trophozoites stained with TRITC-phalloidin (d = ventral disc; m = median body; n = nuclei; and, f = flagella). C, DIC image of cysts. D, Cysts stained with TRITC-phalloidin. E and F, optical slices of D. The B inset represents an optical slice. The nuclei were labelled with DAPI.",
"metadata": {}
},
{
"id": 533,
"image": "PMC2584951_fig3_30360.jpg",
"report": "Immunohistochemical staining for Fas and FasL in paraffin-embedded GIST samples. Representative examples of immunostaining for Fas (A and B) showing predominantly diffuse cytoplasmic staining and FasL (C and D) showing granular cytoplasmic staining (magnification, × 400).",
"metadata": {}
},
{
"id": 534,
"image": "PMC2811169_pntd-0000586-g008_55468.jpg",
"report": "Ultrastructure of ΔLdDC2n/p null mutants flagella.Electron microscopic studies of cross-sections from flagella of chemically fixed L. donovani WT (A), ΔLdDC2n/p-1 (B) and ΔLdDC2n/p-2 (C) promastigotes at the same magnification. Magnifications of L. donovani WT (D) and ΔLdDC2n/p-1 (E). Outer dynein arms (arrows) are missing in the mutant. a, axoneme; p, paraflagellar rod.",
"metadata": {}
},
{
"id": 535,
"image": "PMC2444036_pone-0002702-g003_25101.jpg",
"report": "Confocal laser scanning microscopy of roots colonized by the GFP-tagged endophytic bacterial isolates.(A and B) Root colonization by GFP-tagged BGCR2-8(1) isolate at magnification of 100x (A) and 200x (B) and (C and D) root colonization by GFP-tagged DR5 isolate at magnification of 100x (C) and 200x (D).",
"metadata": {}
},
{
"id": 536,
"image": "PMC2653758_fig1_35830.jpg",
"report": "Expression pattern of HIF-1α in human gastric cancer tissues. Paraffin sections were pretreated as described in Materials and Methods, and HIF-1α was visualised by means of immunohistochemistry. (A) Negative control staining. (B–E) Expression of HIF-1α in established human gastric cancers, showing that the vast majority of tumour cells were positively stained for HIF-1α over nuclei. Magnification × 100 (A and B) and × 200 (C–E).",
"metadata": {}
},
{
"id": 537,
"image": "PMC2914785_pntd-0000778-g001_70587.jpg",
"report": "LruA and LruB-antiserum reacts with lenticular and retinal tissues.(A) Photomicrographs showing uniform homogeneous fluorescence in a section of equine lens incubated with LruA-antiserum (1∶100) but not with preserum (B) (×100). (C) Photomicrographs showing a positive fluorescence in a frozen section of equine retina incubated with LruB-antiserum (1∶100) but not with pre-immunization serum (D) (×100). Inset (×400).",
"metadata": {}
},
{
"id": 538,
"image": "PMC2873933_F4_64561.jpg",
"report": "Staining for CCL5 in whole nasal biopsies during resolution of established inflammation Representative photomicrographs showing CCL5 immunoreactivity in the cytoplasm of cells (brown stain) counterstained with heamatoxylin (blue stain) in negative control placebo-treated individual (A) and placebo-treated (B) and steroid treated individual showing less brown staining compared to placebo treatment (C). Black scale equals 50 μm.",
"metadata": {}
},
{
"id": 539,
"image": "PMC2724506_F2_43240.jpg",
"report": "Images of B. subtilis levansucrase R360K mutant CLEAs. A) CLEAs images obtained immediately after quenching the cross-linking reaction; B) CLEAs washed and centrifuged after cross-linking reaction and C) CLEAs after 48 h of quenching; in this last case, CLEAS were not washed. Digital images were collected in phase contrast mode with a 40×, NA 0.75, Ph 2 objective.",
"metadata": {}
},
{
"id": 540,
"image": "PMC2708193_F1_41419.jpg",
"report": "CXCR4 expression on both tumor cells of primary tumors and metastatic lesions. A) adenocarcinoma, B) squamous cell carcinoma, C) adenocarcinoma (negative control), D) lymph node metastasis, E) bone metastasis, and F) bone metastasis (negative control). Magnification is at 100× for A-C and 200× for D-F.",
"metadata": {}
},
{
"id": 541,
"image": "PMC1526588_F4_6356.jpg",
"report": "Immunocytochemical analysis of BAFF expression in salivary epithelilal cells from minor salivary glands. Positive staining for B cell-activating factor (BAFF) 48 hours after stimulation with IFN-α (2,400 U/ml) (c) and with IFN-γ (5 ng/ml) (d) was markedly enhanced compared with baseline (b). (a) Negative control with polyclonal rat immunoglobulin.",
"metadata": {}
},
{
"id": 542,
"image": "PMC2362056_fig2_21646.jpg",
"report": "Ductal carcinoma in situ specimens with representative immunohistochemical staining patterns for (upper row) bFGF (A), bFGF-R1 (B), VEGF-A (C), Flt-1 (D), KDR (E), and (lower row) VEGF-C (F), Flt-4 (G), ET-1 (H), ETAR (I), ETBR (J).",
"metadata": {}
},
{
"id": 543,
"image": "PMC2956733_F3_76288.jpg",
"report": "HAS 1-3 immunoreactivity and HA-staining in normal and neoplastic human endometrium. Immunostaining of HAS1 (A, B), HAS2 (C, D), HAS3 (E, F) and HA (G, H) in normal human endometrium (A, C, E, G) and in grade 2 endometrioid endometrial carcinoma tissue sections (B, D, F, H). The brown color (DAB) indicates HAS (A-F) or HA (G, H), and blue color (haematoxylin) indicates nuclei. A-F: 200× original magnification. G, H: 100× original magnification.",
"metadata": {}
},
{
"id": 544,
"image": "PMC2669176_pone-0005322-g002_37324.jpg",
"report": "VIP-GnRH interactions.Confocal microscopy photomicrographs of 0.5 µm optical sections showing the relationship between a vasoactive intestinal polypeptide fiber (A: VIP, red) and a GnRH-GFP perikaryon (B: GnRH, green). Panel C shows the superimposed images. Scale bars = 20 µm.",
"metadata": {}
},
{
"id": 545,
"image": "PMC1298337_F3_4024.jpg",
"report": "Immunohistochemical localization of PPARγ in biopsies of the nasal mucosa from control subjects (A) and patients with allergic rhinitis (B), and in polyps before (C) and after treatment with steroids (D). Magnification: ×200.",
"metadata": {}
},
{
"id": 546,
"image": "PMC2887780_F4_66634.jpg",
"report": "Positive immunohistochemical findings (immunoperoxidase technique; ×200). The tumor cells are positive for ACT (a) and VIM (b). Labeling index of Ki-67 (c) is 35%.",
"metadata": {}
},
{
"id": 547,
"image": "PMC2329592_pone-0002063-g001_20581.jpg",
"report": "\nIn vitro salisphere formation.(A) Dissociation of submandibular glands using hyaluronidase and collagenase resulted in clustered cell suspensions. 9723 ± 795 spheres were formed after 2–3 days of culturing (B), which increased in size in time (C,D). BrdU incorporation indicated that the cells in the culture were actively dividing (E–H). BrdU incorporation stained in brown, nuclei in blue. Scale bar = 50 µm. Inset shows negative control for BrdU, scale bar = 20 µm.",
"metadata": {}
},
{
"id": 548,
"image": "PMC2889862_F1_66866.jpg",
"report": "Assessment of spontaneous cortical reaction of oocytes incubated in different media. Goldfish ringer after 5 (A) and 25 min (B) incubation; Synthetic ovarian fluid after 5 (C) and 25 min (D) incubation; goldfish ringer with 0.1 mg/ml STI after 5 (E) and 25 min (F) incubation; trout coelomic fluid after 5 (G) and 25 min (H) incubation. Cortical reaction is visualized by the thin transparent layer appearing around the oocyte. Scale bar = 500 μm.",
"metadata": {}
},
{
"id": 549,
"image": "PMC1434730_F7_5045.jpg",
"report": "Differentiation of cells initiated from embryos 36–44 h.a.o... Cultivated cells from embryos 36–44 h.a.o.. Some cells obtained a differentiated, elongated morphology, unlike cells in cultures from younger embryos. 400 × magnification.",
"metadata": {}
},
{
"id": 550,
"image": "PMC2908605_F5_69536.jpg",
"report": "Base line skin biopsy showing lymphocytic infiltration.",
"metadata": {}
},
{
"id": 551,
"image": "PMC2220003_F1_16874.jpg",
"report": "Appearance of 2–4 cell arrested embryos at day-8 post insemination. Morphological appearance of day-8 in vitro produced bovine embryos. Embryos at this time after in vitro fertilization usually reached the blastocyst stage (a), while arrested embryos still appeared as morphologically normal 2–4 cell embryos (b). (Magnification: 400×).",
"metadata": {}
},
{
"id": 552,
"image": "PMC2740047_fig-003_45282.jpg",
"report": "Histopathological examination of specimen revealed variable cellularity, and spindle cells having bland nuclei, and clear cytoplasm. There was an abundant inflammatory infiltrate comprising plasma cells, lymphocytes, and eosinophils.",
"metadata": {}
},
{
"id": 553,
"image": "PMC2204065_pone-0001520-g001_16265.jpg",
"report": "Late-EPCs can be cultured from peripheral blood mononuclear cells of patients with cKS.A representative phase-contrast photograph of a late-EPC colony, identified as a well-circumscribed monolayer of cobblestone-appearing cells, is shown. Similar colonies were obtained from 15 different patients. A) ×100 magnification, B) ×200 magnification. Late-EPCs were photographed using a Leitz Diavert microscope system.",
"metadata": {}
},
{
"id": 554,
"image": "PMC2952619_pone-0013298-g003_75587.jpg",
"report": "Histopathologic examination of the engrafted tumors by H&E and β-Catenin staining.Surgically removed tumor was fixed in buffered formalin and subsequently analyzed by immunohistochemistry (IHC) by standard protocol.",
"metadata": {}
},
{
"id": 555,
"image": "PMC2323393_F1_20518.jpg",
"report": "BAFF immunoreactivity in breast carcinoma (A), DCIS (B, arrowhead) and normal appearing duct (C, arrow) and lobule (C, arrowhead). Normal adipocytes are stained positively for BAFF (Pannel A, arrowhead). In D, a higher magnification is shown, in which a homogeneous cytoplasmic BAFF immunoreactivity is shown, with more prominent cell membrane staining. E: Normal Ig isotype staining.",
"metadata": {}
},
{
"id": 556,
"image": "PMC2889899_F2_66907.jpg",
"report": "Aurora A, hNinein, and γ-tubulin expression in low- versus high-grade glioma. A, Immunohistochemical analysis of Aurora A expression (brown), 200× magnification. B, hNinein (green) and γ-tubulin (red), counterstained for DNA with DAPI (blue) was assessed by confocal microscopy. Bars = 10 μm, 1000× magnification.",
"metadata": {}
},
{
"id": 557,
"image": "PMC2993681_F3_79856.jpg",
"report": "HER2 overexpression in breast tumors. Representative IHC staining for HER2 expression in invasive breast carcinomas (A-D). HER2 is predominantly membrane-bound (B-D). (A) Tumor that is negative for HER2. (B) Tumor with moderate HER2 staining (HercepTest™ 2+ staining). (C,D) Tumor with strong HER staining (HercepTest™ 3+ staining). Magnification: 100× for C; 200× for A,B,D. Counterstain: Hematoxylin.",
"metadata": {}
},
{
"id": 558,
"image": "PMC1618397_F1_7520.jpg",
"report": "Typical staining of tumour samples with a single-chain antibody against Eag1. Eag1 shows homogeneous cytoplasmic staining with perinuclear localization. Shown are representative examples for the different intensities of Eag1 staining leading to the scoring of 0 (A, morphologically non-malignant skeletal muscle from a rhabdomyosarcoma case), 1+ (B, malignant fibrous histiocytoma), 2+ (C, leiomyosarcoma) and 3+ (D, rhabdomyosarcoma) used for further analysis. Magnification: 20×.",
"metadata": {}
},
{
"id": 559,
"image": "PMC1291371_F4_3892.jpg",
"report": "Representative images of histology (H&E) (first row) and immunohistochemical detection of 3-NT (second row), 4-HNE (third row) and DNP (fourth row) in renal medulla of the four groups of rats studied: CT, HTX, IR, and HTX+IR. (100× magnification).",
"metadata": {}
},
{
"id": 560,
"image": "PMC2488371_pone-0002915-g002_25995.jpg",
"report": "Immunohistochemical images of rat brain cross-sections demonstrating mitochondrial MCT2 in thalamic neurons.When signals from probes for MCT2 (A, green), and mitochondrial COX (B, red) were merged with those of the neuronal marker MAP2 (C, blue), superposition of the signals (D, yellow/white) showed colocalization of MCT2 and components of the mitochondrial reticulum in neurons (white arrows). Scale bar = 20 µm.",
"metadata": {}
},
{
"id": 561,
"image": "PMC2553404_F2_28127.jpg",
"report": "Tyrosine phosphorylation in SYF cells is increased by expressing c-Src or v-Src, but not by FIT-compatible Src. SYF cells were transfected with plasmids expressing GFP-actin alone (A) or in combination with v-Src (C) or FIT-compatible Src (D) while c-Src reconstituted cells were transfected with GFP-actin vector only (B). GFP-actin and anti-pTyr immunofluorescence were observed by confocal microscopy of fixed, permeabilized cells. Merged image is presented on right. Scale bars represent 10 μM.",
"metadata": {}
},
{
"id": 562,
"image": "PMC2813742_fig2_55826.jpg",
"report": "Representative ISH for CCBE1 mRNA in normal ovary using (A) sense negative control and (B) antisense probes, respectively; (C) mucinous ovarian carcinoma; (D) serous ovarian carcinoma; (E) endometrioid ovarian carcinoma, all with antisense probe (magnification × 20).",
"metadata": {}
},
{
"id": 563,
"image": "PMC2848626_F5_61078.jpg",
"report": "Immunohistochemical staining patterns of pRB in dysplastic lesions (L), HNSCC samples (T), normal tissues (Normal) and HNSCC cell lines (Hep2, UPCI: SCC084) samples showing high (a), low/negative (b) expression of pRB protein (indicated by arrows). In #797T, RB1 was not deleted whereas in #944T, this gene was deleted. The regions marked within the circle (20×) were magnified to 40× at inset.",
"metadata": {}
},
{
"id": 564,
"image": "PMC2684356_F0004_38732.jpg",
"report": "Photomicrograph of prostate trucut biopsy, showing collection of epithelioid granulomas with loss of prostatic glands and fibrosis [Figure 3a, H and E, ×40 and 4b, H and E, ×100]",
"metadata": {}
},
{
"id": 565,
"image": "PMC2697143_F3_40096.jpg",
"report": "Fluorescence activated cell sorting (FACS) analysis of mouse trophoblast stem (TS) cells undergoing mitotic cell cycles or endoreduplication as they differentiate into trophoblast giant (TG) cells when deprived of FGF4. p57-/- TS cells respond to the same conditions by forming multinucleated TG cells. Data are from [18].",
"metadata": {}
},
{
"id": 566,
"image": "PMC2792475_F0004_52790.jpg",
"report": "Liver tissue of aqueous leaf extract-treated animals showing normal arrangement of hepatocytes.Section of the liver tissue of aqueous extract of leaf-treated animals showing normal arrangement of hepatocytes around the portal vein (V), absence of necrosis and moderate accumulation of fatty vacuoles (F). Stain H and E, magnification 100X.",
"metadata": {}
},
{
"id": 567,
"image": "PMC2669471_F13_37363.jpg",
"report": "Photo and drawing of Microrhopalodites polynucleatis n. gen., n. sp. R = rostellum, A = axostyle, N = nucleus, Bar = 41 μm.",
"metadata": {}
},
{
"id": 568,
"image": "PMC2883233_F0008_65885.jpg",
"report": "SEM micrographs of indomethacin matrix and coated tablets SEM micrographs of indomethacin matrix and coated tablets after dissolution test in phosphate buffer pH 6.2 at different time interval with magnification of 250",
"metadata": {}
},
{
"id": 569,
"image": "PMC1636656_F7_7723.jpg",
"report": "Fluorescent LnPO4·H2O nanorods were visualized by TEM inside the cytoplasmic compartments of HUVEC. (A-C) EuPO4·H2O nanorods and (D-F) TbPO4·H2O nanorodsare observed inside the HUVEC with increasing magnifications. B was the enlarge picture of white block in A, C was the enlarge picture of white block in B. Similarly, E was the enlarge picture of white block in D and F was the enlarge picture of white block in E.",
"metadata": {}
},
{
"id": 570,
"image": "PMC2775681_pone-0007889-g002_50404.jpg",
"report": "Acadesine induces vacuole formation and degradation of cytoplasmic material.Electron microscopy images showing ultrastructural features of a representative control cell (A) and morphological features of autophagy in K562 treated with 1 mM acadesine for 48 h (B). Cells were observed at different magnification (x2500, x6000 and x25000). L = Lysosome, A = Autophagosome, N = Nuclei, M = Mitochondria, DM = Double Membrane Vesicle.",
"metadata": {}
},
{
"id": 571,
"image": "PMC3047707_fig03_88831.jpg",
"report": "Labeling of target RBC with fluorescent dyes. RBC were labeled with either 20 μM CFDA-SE or 10 μM DDAO-SE and coincubated with an approximately equal quantity of unlabeled RBC for 48 h at +37°C under standard P. falciparum culture conditions. RBC were then harvested and fluorescence detected either by confocal microscopy (top panels) or flow cytometry (bottom panels).",
"metadata": {}
},
{
"id": 572,
"image": "PMC2912230_F1_70129.jpg",
"report": "Scanning electron micrograph of the probiotic strain Lactobacillus salivarius UCC118 at a magnification of 25,000 ×. False colour added by Pat Casey.",
"metadata": {}
},
{
"id": 573,
"image": "PMC2719610_F4_42552.jpg",
"report": "Representative hematoxylin and eosin-stained lung sections collected after assessment of pulmonary mechanics from mice. (B) and (C) is OVA sensitized with single-dose OVA challenge, measured invasively (B) or by Penh measurements (C). (D), (E) and (F) are OVA sensitized with three-dose OVA challenge, measured invasively (D) or by Penh measurements (E, F).",
"metadata": {}
},
{
"id": 574,
"image": "PMC1386683_F5_4687.jpg",
"report": "Immunohistochemical detection of Synd1 in monolayers of NMuMG cells after treatment with LT and hemolytic proteins (1 μg/ml each for 16 h). Nuclei are stained blue with DAPI, and Synd1 is stained green with FITC-conjugated anti-Synd1 antibody. 40× magnification.",
"metadata": {}
},
{
"id": 575,
"image": "PMC1434494_pmed-0030151-g002_5028.jpg",
"report": "Microscopic Characterization of Sectioned Liver Tissue from Patients Who Had Died(A) Light image of a liver tissue section (×100). The central vein is indicated with an arrow.(B) Light image of a liver tissue section (×200).(C) The convergent zone is indicated with an arrow (×100).(D) TEM image of a liver tissue section (×20,000). A bacterium found in the tissue is highlighted with an arrow.",
"metadata": {}
},
{
"id": 576,
"image": "PMC1579243_ppat-0020099-g006_7315.jpg",
"report": "Virions Showing Two Different Modes of Budding(A) The majority of the virions is emerging horizontally from the cell surface and contains nucleocapsids (B), whereas vertically budding virions appear empty. Insets in (A) and (B) are larger magnifications of the areas identified in boxes of the main pictures, depicting cross sections of VLPs. (C) VLPs induced by the expression of VP40 alone bud vertically and lack NC-like structures. Bars, 400 nm.",
"metadata": {}
},
{
"id": 577,
"image": "PMC2700965_pone-0006128-g007_40616.jpg",
"report": "Cellular distribution of ErbB1 and nucleolin mutants.HEK-293T cells were transfected with EGFP-ErbB1 and either pDsRed, pDsRed -nucleolin, pDsRed -N-ter or pDsRed -212-C-ter. 48 h following transfection cells were fixed and subjected to confocal microscopy analysis. GFP-ErbB1 is visualized in green and pDsRed expression vectors are seen in red. Representative cells are presented.",
"metadata": {}
},
{
"id": 578,
"image": "PMC2583968_F5_30113.jpg",
"report": "4 weeks healing time: coverage of the titanium implant with mineralized tissue and dense bone matrix (left) (2 kV, magnification 250-fold). Enlarged detail (right) (2 kV, magnification 1000-fold).",
"metadata": {}
},
{
"id": 579,
"image": "PMC2771033_F1_49801.jpg",
"report": "Distal duodenal biopsy of patient #1 in Group II with celiac disease (hematoxylin & eosin stain).",
"metadata": {}
},
{
"id": 580,
"image": "PMC2621238_F5_32405.jpg",
"report": "Transmission electronic microscopy observations of NPs uptake. Transmission electronic microscope micrographs of LLC-PK1 cells which internalized FW2 (A) and TiO2-15 (B) NPs (MET scale bars A and B: 2 μm, images were taken at ×14 000 and 10 000 magnification).",
"metadata": {}
},
{
"id": 581,
"image": "PMC2673212_F5_37783.jpg",
"report": "Anti-IL-6 antibody reduced the inflammatory histopathology of CIA. DBA/1 LacJ mice were dosed with irrelevant control antibody (A) or anti-IL-6 antibody (1 mg/week (B) or 5 mg/week (C)) for 10 weeks. Mice were sacrificed and joint specimens prepared for histopathological assessment as described in materials and methods. Photomicrographs are 200×.",
"metadata": {}
},
{
"id": 582,
"image": "PMC2222635_F5_16968.jpg",
"report": "Stimulation of MAPK pathway enhances nuclear RNP export of A/HK/218847/06 (H1N1) influenza virus. MDCK cells were infected with H1N1 ± TPA at m.o.i. = 1. RNPs were stained with anti-NP mAb and Alexa488-coupled goat anti-mouse Abs (green). The nucleus was counterstained with TO-PRO-3 (blue). Intracellular RNP localization was analyzed at indicated time points p.i. by multiphoton laser scanning microscopy. The merger of both channels is shown.",
"metadata": {}
},
{
"id": 583,
"image": "PMC2898766_F4_68229.jpg",
"report": "Colocalization of QDs with lysosomes. MCF-7 cells were treated with QD655-COOH for 12 h then incubated with LysoTracker Yellow for specific staining of lysosomes. Fluorescence from each channel was recorded and merged. The orange color seen in the stained cells resulted from the merging of the red fluorescence from QDs and the yellow color of the LysoTracker dye. The white bars represent 20 μm",
"metadata": {}
},
{
"id": 584,
"image": "PMC2768507_f4-co16-5-76_49079.jpg",
"report": "(A) Metastatic colonic adenocarcinoma showing a tubular growth pattern. (B) Focally, the tumour showed heavy lymphocytic infiltration and small-vessel proliferation. (C) Metastatic adenocarcinoma infiltrating the adventitia of a large venule. Note the garland necrosis. (D) Surrounding hepatic tissue showing macrovesicular steatosis. All panels: Hematoxylin and eosin stain, 400× magnification.",
"metadata": {}
},
{
"id": 585,
"image": "PMC2774669_F7_50278.jpg",
"report": "Morphological properties of HET-s PFD aggregates present at the final time point of soluble monomer non-seeded aggregation reactions (top panel) or at the final stage of reactions seeded with HET-s(001-289) (top-middle panel), HET-s(157-289) (bottom-middle panel) and HET-s(218-289) IBs (bottom panel) as monitored by transmission electronic microscopy.",
"metadata": {}
},
{
"id": 586,
"image": "PMC1383488_ppat-0020013-g008_4633.jpg",
"report": "Colocalization of T. gondii Centrin-2 and DLCFluorescence images (projections of a deconvolved 3D stack) of two different vacuoles (A–C) (D–F), each containing four parasites expressing both EGFP–TgDLC and mRFP–TgCentrin2. Blue brackets in (A–C) mark the position of the apical cap of dynein. Note that the ring of TgCentrin2 spots is always positioned at the lower border of this cap. The arrowheads in (D–F) indicate the faint basal ring of dynein that lies adjacent to the basal spot of centrin2.",
"metadata": {}
},
{
"id": 587,
"image": "PMC2770038_F8_49600.jpg",
"report": "Topography of αSMA positive cells 7 days after pneumonectomy. Photomicrograph (400× magnification) with αSMA (green), BrdU (red) and nuclei (blue), illustrating αSMA staining around a vessel, but not in surrounding alveoli or associated with BrdU positive cells. Similar results were seen at 3 days after pneumonectomy and in sham-operated animals (results not shown).",
"metadata": {}
},
{
"id": 588,
"image": "PMC2527805_fig7_27203.jpg",
"report": "Immunohistochemical visualisation of COX-1, COX-2, EP1 receptor and FasL in human colon cancer. (A) Cyclooxygenase-2 and FasL, (B) COX-1 and FasL and (C) EP1 receptor and FasL immunostaining in cancer cells, with the upper and lower panels representing different colon cancer specimens. Specific protein stained brown. (D) Rabbit, goat and mouse controls demonstrated no staining. Representative micrographs are shown. Original magnification: × 300.",
"metadata": {}
},
{
"id": 589,
"image": "PMC2714488_F4_42006.jpg",
"report": "Transmission of hypovirulence and its associated traits of strain XG36-1. A, the colony of hygromycin-resistant gene labelled strain XG36-1A34R was converted when dual culturing with hypovirulent strain XG36-1(red triangle). B, the hyphae at the colony margin of strain XG36-1A34R branched excessively as strain XG36-1 did. C, converted strain XG36-1A34R also lost virulence on detached rapeseed leaves.",
"metadata": {}
},
{
"id": 590,
"image": "PMC549033_F4_1291.jpg",
"report": "Phenotype analysis of lymphocytes infiltrating the tumor site in responder patient 1. Obvious infiltration of a larger number of CD4+ or CD8+ T cells and a small number of CD20+ B cells is shown. Indirect staining using anti-CD4, CD8, CD20 or CD56 MoAb as primary Ab and goat anti-mouse Ab as secondary Ab was performed. Magnification × 200.",
"metadata": {}
},
{
"id": 591,
"image": "PMC2693426_F6_39648.jpg",
"report": "CLSM specificity analysis of GM130 and EEA1 labeling. Isosurface representation of the cell shows the nucleus (blue) labeled with Hoechst 33342, Golgi complex (GM130) and endosomal system (EEA1) (red) within a three-dimensional volumetric x-y-z data field. Scale bar = 10 μm.",
"metadata": {}
},
{
"id": 592,
"image": "PMC3040715_F3_87493.jpg",
"report": "STED microscopy dissecting the localization of Na+,K+-ATPase in cultured striatal neurons. The 5 × 3 mosaic shows a comparision of the confocal (left) and STED images (middle) of the Alexa-594 immunolabelled α3 NKA in dendritic spines. Postprocessing of the raw STED data by a Richardson-Lucy deconvolution further enhances the details as shown in the right row of images. Scale bar: 500 nm",
"metadata": {}
},
{
"id": 593,
"image": "PMC3014736_f04_82861.jpg",
"report": "\nScopelodes contracta larva on a Celtis sinensis leaf just after reaching the ground by parachuting. Scale bar: 10 mm. High quality figures are available online.",
"metadata": {}
},
{
"id": 594,
"image": "PMC2438330_F1_24699.jpg",
"report": "Expression of AMACR in HCC and non-HCC tissue. A, normal liver tissue (background staining, grade 0). B, hepatocellular adenoma (background staining, grade 0). C, cirrhotic nodules (weakly positive, grade 1+). D, well-differentiated hepatocellular carcinoma (strongly positive, grade 3+). (immunohistochemical staining; original magnification ×200)",
"metadata": {}
},
{
"id": 595,
"image": "PMC1810241_F4_9896.jpg",
"report": "Morphological changes of cell cultures infected with WR and Wyeth strains at 3 days post-infection. (A) Plaque formation in Vero E6 and EA.hy926 cells. (B) Morphological changes of CV-1, primary mouse lung cells (Lung), MLEC and primary mouse kidney cells (Kidney) at 200 × magnification. Cells were infected with WR or Wyeth strains at m.o.i. 1 and observed after 2 days post-infection.",
"metadata": {}
},
{
"id": 596,
"image": "PMC3008598_fig1_81937.jpg",
"report": "IHC pictures using anti-Src family negative regulatory [pY] site antibody and Clone28 antibody; magnification × 400. (A) Illustrates invasive breast cancer immunohistochemically stained with anti-Src family negative regulatory (pY) site antibody (Invitrogen, 1 : 1500); moderate staining of nuclei, weak staining of cell cytoplasm and membrane can be seen. (B) Demonstrates strong perinuclear staining in invasive breast cancer stained with Clone28 antibody (Invitrogen, 1 : 500).",
"metadata": {}
},
{
"id": 597,
"image": "PMC2180173_F2_15882.jpg",
"report": "Fluorescence patterns of representative chimeric proteins in tobacco protoplasts. Image of a tobacco protoplast transformed with pG2HPLE1-YFP (a), pG2HPLF1-YFP (b), pG2HPLF2-YFP (c), pG2HPLF3-YFP (d) chimeric constructs. The scale bar corresponds to 20 μm.",
"metadata": {}
},
{
"id": 598,
"image": "PMC2955717_F1_76144.jpg",
"report": "Electron micrograph of phage LSB-1. Electron micrographs of the phages with a short, stout tail. The polyhedral nature of the viral head is shown.",
"metadata": {}
},
{
"id": 599,
"image": "PMC1936995_F2_12566.jpg",
"report": "high power H & E stain and S100 stain of biopsy.",
"metadata": {}
},
{
"id": 600,
"image": "PMC3012086_pone-0015741-g004_82598.jpg",
"report": "Optical projection tomography of 5F7-LacZ stained embryos.Optical projection tomography (OPT) images of selected LacZ stained embryos. One representative embryo for each orthologous mouse human and chicken enhancer was selected. Arrowheads highlight expression in the trigeminal ganglion. Top: sagittal sections. Bottom: frontal sections. (Right) In situ hybridisations for Olig1 and Olig2 genes.",
"metadata": {}
},
{
"id": 601,
"image": "PMC2330033_F7_20763.jpg",
"report": "Double immunostaining of IgG extravasation and the expression of GFAP. Cholesterol-enriched diet markedly enhanced the immunopositive staining of GFAP (green) around the sites where IgG extravasation (red) was present. These effects were blocked by caffeine at the dose of 3 mg/day. Representative images taken from 2 rabbits in each group with 6 sections from each animal are shown. Bar = 20 μm.",
"metadata": {}
},
{
"id": 602,
"image": "PMC1502135_F3_6048.jpg",
"report": "Increased level of apoptosis in the gonads of Skp2-/- mice. (A, B) TUNEL staining of testicular sections of Skp2+/+ (A) or Skp2-/- (B) mice at 4 months of age. Arrowheads indicate apoptotic cells. Scale bars, 100 μm. (C) The number of apoptotic spermatogenic cells per 100 Sertoli cells. *P < 0.05 versus Skp2+/+. (D) Ultrastructural image of typical apoptotic figures (arrowheads) at late postmeiotic stages of spermatogenesis in a Skp2-/- mouse at 4 months of age. Scale bar, 5 μm.",
"metadata": {}
},
{
"id": 603,
"image": "PMC1937022_pone-0000754-g002_12650.jpg",
"report": "Expression of Hoxd genes in catshark pectoral fins.Stages of development indicated in lower right corners of each panel. (A–D) Whole mount in situ hybridizations showing expression of Hoxd9 (A), Hoxd10 (B), Hoxd12 (C) and Hoxd13 (D). Pect, Pectoral fin bud; Cl, cloaca. Note anterior expansion of Hoxd12 and Hoxd13 in distal fin at stage 32. Arrows mark anterior limits of expression. Yellow dotted lines in the left column mark the anterior boundaries of expression at stage 22.",
"metadata": {}
},
{
"id": 604,
"image": "PMC2410161_fig1_23913.jpg",
"report": "Negative liver staining for SCCA variants by immunohistochemistry in normal human liver (staging liver biopsy from a patient with mediastinal Hodgkin's disease). Original magnification: × 20.",
"metadata": {}
},
{
"id": 605,
"image": "PMC2654462_F3_35913.jpg",
"report": "Subcellular localization of the antigen of McAb4E7. (A and B) The targeting antigen mainly located in the cellar membrane both in lung adenocarcinoma and squamous carcinoma (C) A little expression of the targeting antigen could be seen in the cytoplasm in the adjacent nontumourous lung tissues (D) The targeting antigen was not be found in the SCLC tissues; Magnifications: A-D × 40.",
"metadata": {}
},
{
"id": 606,
"image": "PMC2483279_F4_25823.jpg",
"report": "Primary culture of Sertoli cells from EGFP transgenic mice (FM131) transfected with pGtoR. The analysis was performed at 120 h (A, B and C) and 140 h (D, E and F) after transfection. Green fluorescence (excitation wavelength 488 nm) (A and D). Red fluorescence (B and E). Merge (C and F). Transfected cells (as demonstrated by red fluorescence) are indicated by arrows. Bar represents 10 μm.",
"metadata": {}
},
{
"id": 607,
"image": "PMC3002327_F1_81193.jpg",
"report": "Immunofluorescence staining of GSK-3β in ALL cells. Bone marrow samples were obtained from children with ALL and from control patients. GSK-3β was probed with Dylight 549-labeled anti-rabbit secondary antibody (red fluorescence) and nuclei were counterstained with Hoechst 33342 (blue fluorescence). Nuclear accumulation of GSK-3β in ALL cells was detected, whereas only cytoplasmic expression of GSK-3β was observed in control cells.",
"metadata": {}
},
{
"id": 608,
"image": "PMC2942817_F1_74109.jpg",
"report": "Actinomycete species isolated from attine ants. Actinomycete species isolated from Acromyrmex octospinosus worker ants viewed under a light microscope at 40 × magnification. Streptomyces strains are numbered S1-S9 and Pseudonocardia strains P1-P2.",
"metadata": {}
},
{
"id": 609,
"image": "PMC2222674_F2_17036.jpg",
"report": "Result of FISH analysis using LSI probe (TUPLE 1) from DiGeorge/velocardiofacial syndrome critical region. TUPLE 1 (HIRA) probe was labeled in Spectrum Orange and Arylsulfatase A (ARSA) in SpectrumGreen as control. Absence of the orange signal indicates deletion of the TUPLE 1 locus at 22q11.2.",
"metadata": {}
},
{
"id": 610,
"image": "PMC3034990_fig1_86539.jpg",
"report": "Peridural fibrosis at the sham operated (untreated; group A) site showing increased numbers of fibroblasts which are consistent with fibrosis formation (Arrows; Hematoxylin and eosin; ×400).",
"metadata": {}
},
{
"id": 611,
"image": "PMC2335107_F7_20789.jpg",
"report": "Histological examples of alveolar edema (25*), septal edema (100*) and intra-alveolar hemorrhage (40*) on HE slides. LIRI caused alveolar and septal edema and alveolar hemorrhages, which were most severe on day 1 and 3 after LIRI and resolved thereafter. On day 7 brownish macrophages were found after clearance of erythrocytes in the alveolus. HE = Haematoxylin and Eosin staining; LIRI = Lung Ischemia-Reperfusion Injury.",
"metadata": {}
},
{
"id": 612,
"image": "PMC2361857_fig2_21574.jpg",
"report": "Anti-NP1 and anti-KDR peptide binding. Tumour and endothelial cells were incubated with 5-(6)-carboxyfluorescein-labelled anti-NP1 and anti-KDR peptides on chamber slides for 18 h. Peptide binding to the VEGF receptors, NP-1 and KDR, was examined on 4T1 (A), MDA-MB-231 (B) and HUVEC (C) cells by confocal microscopy (× 400 magnification). Images are representative of a scan zoom of between 1- and –4.2-fold.",
"metadata": {}
},
{
"id": 613,
"image": "PMC3022910_F5_84726.jpg",
"report": "Chloroplast localization of SVR3. Representative wild-type Arabidopsis leaf protoplasts transiently expressing the control GFP vector ([A]-[C]) or the P35S:SVR3 CTP:GFP vector ([D]-[F]). Green fluorescence signals from GFP ([A] and [D]) and chlorophyll autofluorescence ([B] and [E]) were monitored by confocal microscopy. (C) and (F) are merged images from (A) &(B) and (D) &(E), respectively. Bar represents 5 μm.",
"metadata": {}
},
{
"id": 614,
"image": "PMC3078860_F5_92673.jpg",
"report": "Histological section of the papillary renal cell carcinoma of the upper pole with a papillary, tubulopapillary and cystic growth pattern of cancer cells (hematoxylin and eosin counterstain, magnification ×100).",
"metadata": {}
},
{
"id": 615,
"image": "PMC1794249_F2_9324.jpg",
"report": "Morphology of cultured adult rat RGCs. The cells, cultured for 3 (A & B), 7 (C & D), and 11 (E & F) days, were labeled with anti-Thy-1 antibody (red) and DAPI nuclear stain (blue). (B), (D), are (F) are the corresponding phase-contrast images. Scale bar = 50 μm.",
"metadata": {}
},
{
"id": 616,
"image": "PMC2395272_fig4_23255.jpg",
"report": "Microscopic changes of tumour vascularity in patients with breast cancer treated by HIFU. (A) Untreated tumour blood vessels; (B) destruction of tumour vascularity with disruption of the endothelium and tunica media, H&E staining × 400. (C) untreated tumour vessel wall; (D) destroyed tumour blood vessels with the collapse and disruption of vascular elasticity fibrin and collagen fibrin, Victoria blue and ponceau's histochemical staining × 400.",
"metadata": {}
},
{
"id": 617,
"image": "PMC3049781_pone-0017559-g004_89192.jpg",
"report": "Effect of chloranil on the laminin-induced co-clustering of ß-DG and AQP4.Primary astrocytes were treated for 7 h with 20 nM laminin and15 µM chloranil during the last 4 h. The concentration of chloranil varied from 0 (A,B,C), 6(D,E,F), 12(G,H,I), 25 (J,K,L), 50 (M,N, O) to 100 µM (P,Q,R). The cells were fixed and labelled for μ-DG (A, D, G, J, M and P) and AQP4 (B, E, H, K, N and Q). Clustered staining was quantified using confocal microscopy. Scale bar, 30 µm.",
"metadata": {}
},
{
"id": 618,
"image": "PMC2824827_pone-0009318-g004_57392.jpg",
"report": "Examination of brain tissues and eyes by H&E staining.Embryos at 48 hpf after control or nestin MO injection were sectioned at midbrain (A and B) and hindbrain (C and D) levels. Tissues were stained with H&E. Eyes at the midbrain level were visualized and shown in E and F. The scale bar is 50 µm.",
"metadata": {}
},
{
"id": 619,
"image": "PMC1289279_F3_3878.jpg",
"report": "Infiltrated lymph nodes from G1 (a) and G3 (b) LBC show tumoral glands positive for HSP60. Metastases also show glands positive for HSP10 in both G1 (c) and G3 (d) carcinomas (Magnification: 40×). HSP60 positivity shows vascular (e) and neural (f) invasion by cancer (Magnification: 10×).",
"metadata": {}
},
{
"id": 620,
"image": "PMC538264_F3_856.jpg",
"report": "Angiotensin II receptor 1 staining in lung biopsies from control patients (A) and from patients with idiopathic pulmonary fibrosis (B). Immunohistochemistry for the angiotensin II receptor 1 (AGTR1), counterstained with haematoxylin. AGTR1 positive staining is seen in alveolar macrophages, in epithelial cells and in fibroblastic foci (arrows) in usual interstitial pneumonia biopsies (panel B). Epithelial cells and alveolar macrophages express AGTR1 in control lung biopsies (panel A).",
"metadata": {}
},
{
"id": 621,
"image": "PMC1994067_F2_13819.jpg",
"report": "Typical FESEM images and TEM images of the γ-Mn3O4 spheres with radiated spherulitic nanorods. a: FESEM image at a low magnification, indicating that the γ-Mn3O4 spheres can be fabricated on a large scale. b: FESEM image at a high magnification, revealing the nanorods were fixed on the surfaces of the spheres. c: TEM image of the γ-Mn3O4 radiated spherulitic nanorods. d: The corresponding SAED pattern of the γ-Mn3O4 products.",
"metadata": {}
},
{
"id": 622,
"image": "PMC1885430_F3_11299.jpg",
"report": "Kidney biopsy showing mesangial proliferative changes (haematoxylin and eosin stain, original magnification ×100).",
"metadata": {}
},
{
"id": 623,
"image": "PMC1174941_F3_2438.jpg",
"report": "Peptidyl arginine deiminase 4 (PAD4) is present in the arthritic joint. PAD4 was detected in infiltrating cells (a), localised to the cytoplasm of mononuclear cells (c,e). Unimmunised animals were negative for PAD4 staining (f). Immunohistochemical stainings were performed with a rabbit anti-PAD4 antibody. Control staining was performed with preimmune rabbit sera (b,d) (Original magnifications: ×40 (a,b,f); ×200 (c-e)).",
"metadata": {}
},
{
"id": 624,
"image": "PMC2774948_pone-0007908-g003_50321.jpg",
"report": "Effect of time on epithelialization.All skin equivalents demonstrated a stratified epithelium on the upper surface within one week. With H-Ras overexpression keratinocyte invasiveness typically occurred early and slowed with time. Similar results occurred with all H-Ras permutations. All but Ker-CT-Ras-T retained some ability to cornify. Upper images, 40× total magnification; lower images, 400× total magnification. Scale bar: 100 µm.",
"metadata": {}
},
{
"id": 625,
"image": "PMC2720210_fig2_42695.jpg",
"report": "Immunohistochemical staining of ANX2 in primary RCC and its metastases. (A) Grade 1 clear-cell carcinoma, (B) grade 2 clear-cell carcinoma, (C, D) ANX2 is highly expressed along the periphery and around vessels. (E) Lung metastasis, (F) bone metastasis, (G) neck lymph node metastasis and (H) brain metastasis. Magnification at × 20; Scale bar, 100 μm.",
"metadata": {}
},
{
"id": 626,
"image": "PMC2435540_F3_24641.jpg",
"report": "Accumulation of chlorophyll and the GFP-BC protein in the tGBCch seedlings during greening. The fluorescence images of the Arabidopsis cotyledons during greening for 24 h were observed with confocal microscopy. The GFP-CAO protein and the plastids during greening are indicated by green and red fluorescence, respectively. The green fluorescence of GFP-BC protein was detected only within plastids during greening.",
"metadata": {}
},
{
"id": 627,
"image": "PMC2164959_F8_15613.jpg",
"report": "HPV16 E5, M2 and M3 mutants but not M1 mutant strongly co-localize with calnexin. HaCaT cells were transfected with A) AU1-tagged codon-optimised E5 or AU1- tagged codonoptimised E5 mutants M1 B), M2 C), and M3 D) and analysed after 24 h by confocal laser scanning microscopy using a monoclonal anti-AU1 and polyclonal anticalnexin antibodies.",
"metadata": {}
},
{
"id": 628,
"image": "PMC2410163_fig3_23916.jpg",
"report": "CHEK2 protein expression. Nonmutated squamous cell carcinoma in (A), nonmutated adenocarcinoma in (B). The remaining samples are from the four mutated tumours: adenocarcinomas T1, T2 and T3 shown in (C–E), squamous cell carcinoma T4 shown in (F). Magnification × 100 (B, E), × 50 (A, C, D, F). Note the strong nuclear CHEK2 immunoreactivity in the tumour cells.",
"metadata": {}
},
{
"id": 629,
"image": "PMC2777385_pgen-1000750-g004_50866.jpg",
"report": "Abnormal localization of collagen in CypB–deficient cells.MEFs prepared from wild-type (WT) or CypB knockout mice (KO) were cultured with or without 24hr stimulation with ascorbic acid (+AS). Cells were fixed, permeabilized, and co-stained for intracellular collagen and the Golgi marker GM130 (A) or the ER-resident protein PDI (B). (bar = 40 µm).",
"metadata": {}
},
{
"id": 630,
"image": "PMC2906480_F1_69186.jpg",
"report": "The D2-40-positive lymphantics mainly located at the layer of submucosa in gastric tissue (arrows). IHC, magnification: ×200.",
"metadata": {}
},
{
"id": 631,
"image": "PMC2992999_f4-marinedrugs-08-02659_79819.jpg",
"report": "Apoptotic morphology induced by cyanobacterial extracts in AML cells. Rat leukemia cells (A: control) were added the aqueous extract of the cyanobacterial strain M27 (B), M30 (C), M44 (D) or 50 nM daunorubicin (DNR, E) as described in the legend to Figure 1, and photomicrographs were taken using differential interference contrast (upper) and UV (lower). Bar represent 10 μm.",
"metadata": {}
},
{
"id": 632,
"image": "PMC2776370_F0003_50582.jpg",
"report": "Histological examination and immunohistochemical (IHC) profiles of the resected tumors; (a) Epithelioid cell proliferation suggests gastrointestinal stromal tumors (H and E, ×400); (b) IHC staining positive for CD-117 (brown color); (c) Predominantly spindle cells (H and E, ×100); (d) IHC showing a diffuse positive signal for CD-34 (H and E, ×100)",
"metadata": {}
},
{
"id": 633,
"image": "PMC3014813_f04_82900.jpg",
"report": "Scanning electron micrographs of sound-producing structures in Oreta rosea. (A) An anterior view of a lateinstar larval head capsule showing the position of the left mandible (arrow, scale bar = 500 µm). (B) Higher magnification of a single mandible showing the serrated edge that is scraped against the leaf surface (scale bar = 100 µm), High quality figures are available online.",
"metadata": {}
},
{
"id": 634,
"image": "PMC2890656_F5_67101.jpg",
"report": "Observation of subcellular localization using confocal laser scanning microscopy. The subcellular location of wild type and mutant prM was visualized by double-staining of the infected Sf9 cells. The ER compartment was stained with 10 nM DiIC13(3), and the prM proteins were stained with mAb 5B1, followed by goat anti-mouse Alexa Fluor 647 IgG. Photographs were taken with appropriate excitation laser wavelengths and merged to reveal the co-localization of prM and ER compartment.",
"metadata": {}
},
{
"id": 635,
"image": "PMC2822849_pone-0009260-g006_56936.jpg",
"report": "Differentiation of BrdU-positive cells in the dentate gyrus in rats 28 days after the subchronic treatment with fluoxetine.BrdU-positive cells (green) were co-labeled with a neuronal marker, NeuN (A), but not GFAP (B). Scale bars: 400 µm in lower magnification and 40 µm in higher magnification.",
"metadata": {}
},
{
"id": 636,
"image": "PMC2214726_F1_16674.jpg",
"report": "Life stages of Gregarina sp. infecting Romalea microptera grasshoppers. A. Fresh smear of trophozoite with epimerite; B. Gamonts on conjugation-stained with Heidenhain's iron haemotoxylin ; C. Gametocyst on sporulation (vertical arrow – unsporulated gametocyst, right arrow – coiled spores, inner picture – gametocyst showing sporoducts); D. Fresh spores",
"metadata": {}
},
{
"id": 637,
"image": "PMC1361788_F1_4479.jpg",
"report": "TIRF-M images of mGluR1-GFP fluorescence in SCG neurons expressing the receptor alone, \"mGluR1-GFP\", or with co-expression of the indicated Homer protein. Two representative neurons from each group are shown. The total number of neurons examined for each group were: mGluR1-GFP (19 cells), + Homer 1a (5), + Homer 1b (6), + Homer 1c (9), + Homer 2b (8), + Homer 3 (10).",
"metadata": {}
},
{
"id": 638,
"image": "PMC2805682_F10_54711.jpg",
"report": "Histological observation of the lung in four groups (A-D). (A): The normal lung of group NS (HE × 100); (B) Many metastatic nodes in the lung of group SACC-M (HE × 100); (C) Many metastatic nodes in the lung of group SACC-M-HK (HE × 100); (D) Only a few smaller metastatic nodes in the lung of group SACC-M-WJ4 (HE × 100).",
"metadata": {}
},
{
"id": 639,
"image": "PMC1664555_F3_7846.jpg",
"report": "Laser mediated heat shocks. (a) Transgenic wing tissue showing EGFP expressing cells as a result of a line heat shock. (b) Higher magnification of EGFP expressing cells. (c) Wildtype wing tissue after line heat shock. (d) Complex grid pattern of EGFP expression. (e) Complex butterfly pattern of EGFP expression as a result of laser heat shock. Scale bar = 100 μm in all panels.",
"metadata": {}
},
{
"id": 640,
"image": "PMC2770460_F5_49683.jpg",
"report": "C-Tpr import into the nucleus is cytosol, temperature and energy dependent and is blocked by WGA. Digitonin-permeabilized NRK cells were incubated with 8 pmoles of Cy5-C-Tpr for 20 min at 30°C (panel A) or 4°C (panel B) in the presence of cytosol and an energy-regenerating system. Panel C: 8 μg WGA was added. Panel D: the ATP regenerating system was replaced by an ATP-depleting system, 0.8885 U hexokinase + glucose. Samples were visualized by confocal microscopy.",
"metadata": {}
},
{
"id": 641,
"image": "PMC2915960_F1_70662.jpg",
"report": "Calretinin. Predominantly nuclear, less cytoplasmatic staining. Epithelial type MM, pleura. Biopsy, 400×. Pat. no. 1.",
"metadata": {}
},
{
"id": 642,
"image": "PMC2174466_F5_15804.jpg",
"report": "Accumulation of autofluorescent compounds in Physcomitrella after CF treatment and B. cinerea inoculation. Examination of UV-stimulated autofluorescence of B. cinerea-inoculated leaf (A, C), PDB-treated leaf (B), PDB- (D), B. cinerea spores- (E), LB- (F) and CF(SCC1)-treated protonemal filaments (G). A closer view of a CF(SCC1)-treated protonemal cell with cytoplasmic shrinkage and UV-stimulated autofluorescence is shown (H, I). Observations were made 2 days after treatments.",
"metadata": {}
},
{
"id": 643,
"image": "PMC2546414_F1_27914.jpg",
"report": "Hematoxylin and eosin stain of retroperitoneal mass biopsy consistent with classic seminoma. Magnification ×40.",
"metadata": {}
},
{
"id": 644,
"image": "PMC2844405_F3_60194.jpg",
"report": "Left: Artificial mixture of F. tularensis subsp. tularensis (Schu S4, red circle) and F. philomiragia (ATCC 25017, green circle), phase contrast microscopy. Right: Fluorescence microscopy after hybridization with probes Bwall1448-Cy3 and Bwphi1448-6-FAM with 50% formamide. The green, pleomorphic cells of F. philomiragia can be easily distinguished from the smaller, coccoid rods of the highly virulent F. tularensis subsp. tularensis strain showing red fluorescence.",
"metadata": {}
},
{
"id": 645,
"image": "PMC2361510_fig2_21485.jpg",
"report": "Immunohistochemical localisation of voltage-gated Na+ channel (VGSC) protein expression in human lung tissues, using a commercial pan-VGSC antibody. (A and B) SCLC, (C and D), normal lung epithelia. Voltage-gated Na+ channel immunoreactivity showed marked upregulation in SCLC (B\nvs\nD). Left hand panels (A and C) represent phase contrast images, right hand panels (B and D) are bright field images. Scale bar, 15 μm, applicable to all parts of the figure.",
"metadata": {}
},
{
"id": 646,
"image": "PMC2234406_F2_17387.jpg",
"report": "Scanned images of DAB-stained, spotted immobilised rHRP activity. WT, Wildtype; Mutant 1, R118K/R159K/R283K; Mutant 2, R118K/R159K; Mutant 3, R118K/R159K/K232N/K241F/R283K; Mutant 4, R118K/R159K/K232N/K241F. Time points indicated on the left are in hours. DAB coloration indicates peroxidase activity; this was noted within minutes for the immobilisation mutants, whereas plant and wildtype recombinant HRP required a longer time to develop any coloration.",
"metadata": {}
},
{
"id": 647,
"image": "PMC2253695_fig03_18113.jpg",
"report": "Lung histology in WT and TLR2 KO mice after infection with S. pneumoniae PLN. Representative lung tissue slides from WT mice (A, C and E) and TLR2 KO mice (B, D and F) after infection with 5 × 107 cfu S. pneumoniae PLN. Mice were sacrificed after 24 h (A and B), 48 h (C and D) or 72 h (E and F). HE staining: magnification 4×.",
"metadata": {}
},
{
"id": 648,
"image": "PMC3083678_f3-ijms-12-00865_93573.jpg",
"report": "Results for puma dataset. (A) Five clusters identified by TESS. (B) Three clusters identified by BAPS5. (C) Three clusters identified by GENELAND. (D) Significant boundary elements (black circles) detected by WOMBSOFT. Small dots indicate sampling sites. Puma habitat is shown in grey.",
"metadata": {}
},
{
"id": 649,
"image": "PMC1097755_F5_2136.jpg",
"report": "Fluorescence microscopy. L. donovani promastigotes transfected with a CPN10/GFP gene chimera on plasmid pIRCPN10::GFP were subjected to bright field microscopy at 63× magnification (panels A-C). The same microscopic fields were viewed under UV excitation at XXX nm (panels D-F). Panels G-I show the overlays.",
"metadata": {}
},
{
"id": 650,
"image": "PMC2453234_pone-0002754-g003_25250.jpg",
"report": "Confocal fluorescence microscope images of PECAM-1 stained sections (50 µm thick) cut from the piriform region of brains fixed at the end of the electrophysiological experiment.CFDA green fluorescent NCs and brain vessels are shown at different magnifications. Calibration bar = 100 µm. NCs were observed in close proximity to cerebral vessels.",
"metadata": {}
},
{
"id": 651,
"image": "PMC2885652_f6_66155.jpg",
"report": "Transmission electron micrographs of F. magna adhering to keratinocytes. Keratinocytes were incubated 2 h with ALB8 (a, b) or CK05 bacteria (c, d). The cells were then washed and incubated with buffer (a, c) or with plasma (b, d) prior to analysis by transmission electron microscopy. Fibrin fibrils are indicated (arrows). The insert in (d) shows a higher magnification of a fibrin fibril. Scale bars: 0.5 μm (left) and 100 nm (right).",
"metadata": {}
},
{
"id": 652,
"image": "PMC3072396_pone-0018529-g001_92012.jpg",
"report": "Photographic time series of gill lesions in fish exposed to Aurelia aurita under experimental challenge.Times expressed in hours from the start of the experiment. A: Healthy gills from control group (0 hr). B–F: Gills from experimental treatment groups. B: 2 hrs. C: 6 hrs. D: 24 hrs. E: 48 hrs. F: 3 wks. Using haematoxylin and eosin at 200× magnification.",
"metadata": {}
},
{
"id": 653,
"image": "PMC2267462_F3_18988.jpg",
"report": "Tissue sections from clinical Biopsies labelled with clone R24.1 mab. On the left panel, a HL tissue section shows intense staining with a membrane and Golgi pattern. On the right panel, an ALCL tissue section shows intense staining of neoplastic ALCL cells. Magnification ×400.",
"metadata": {}
},
{
"id": 654,
"image": "PMC2903469_pntd-0000740-g005_68669.jpg",
"report": "Fluorescent T. cruzi-tdTomato expressing parasites imaged post-treatment.Mice (10 per group) were infected in the hind foot pads with 2.5×105\nT. cruzi tdTomato trypomastigotes and the images were taken every two days from day 1 to 11 post infection. (A) Images from days 5, 7 and 9 post infection. (B) Quantification of the fluorescent signal from mice in panel A at all imaging points.",
"metadata": {}
},
{
"id": 655,
"image": "PMC2661321_F9_36618.jpg",
"report": "Assessment of AVOs formation by acridine orange staining. BA induces autophagy in ADF cells. A representative example of acridine orange stained cells. Bright orange granules are evident in BA and CsA+BA treated cells. As specificity control, cells treated with 200 nM bafilomycin A1 (BAF) for 30 minutes before the addition of acridine orange do not show AVOs formation.",
"metadata": {}
},
{
"id": 656,
"image": "PMC555600_F3_1468.jpg",
"report": "Strong cytoplasmic immunohistochemical staining of tumor cells for VEGF in a CUP case. It is shown the characteristic granular cytoplasmic staining pattern and the occasionally weak positive reaction of intervening stromal and endothelial cells (original magnification ×200, counterstained with hematoxylin)",
"metadata": {}
},
{
"id": 657,
"image": "PMC1533842_F4_6437.jpg",
"report": "Identification of infected cells within the trigeminal ganglia. Two days after intracutaneous/intranasal inoculation of PrV-614/PrV-Cam both, red and green fluorescence could be detected in cryosections of the right trigeminal ganglion but never was colocalized. Bars in A and B: 50 μm",
"metadata": {}
},
{
"id": 658,
"image": "PMC1184092_F2_2692.jpg",
"report": "Thick, deep blue colloid material with bubble pattern in FNA of a benign colloid nodule (Diff-Quik stain, × 250) view).",
"metadata": {}
},
{
"id": 659,
"image": "PMC2387169_F2_22822.jpg",
"report": "ERβ immunostaining on paraffin-embedded invasive breast cancer using antibody from Chemicon (40× magnification).",
"metadata": {}
},
{
"id": 660,
"image": "PMC2395306_fig3_23266.jpg",
"report": "Evaluation of tumour angiogenesis. Identification of external border of tumour growth at × 40 (A) and × 100 (B) magnification field: I (desmoplastic stroma), II (infiltration zone), and III (tumour). At × 250 magnification field (C and D), it is possible to appreciate the differences in the degree of MVD between tumours.",
"metadata": {}
},
{
"id": 661,
"image": "PMC2876759_F3_64915.jpg",
"report": "Adult trematodes isolated from Vietnamese persons. A) Haplorchis pumilio. B) H. taichui. C) H. yokogawai. D) Stellantchasmus falcatus. (Semichon acetocarmine stained, magnification ×120.)",
"metadata": {}
},
{
"id": 662,
"image": "PMC2809415_fig2_55306.jpg",
"report": "SEM photomicrographs of S. \nepidermidis adhered to acrylic (a)\nand silicone (b) surfaces. Strains: A—IE214; B—IE186; C—9142; D—9142-M10; E—1457; F—1457-M10; G—IE75; H—LE7. The arrow shows bacterial cells\nadhered along a depression on silicone's surface. Magnification ×3000, bar = 10 μm.",
"metadata": {}
},
{
"id": 663,
"image": "PMC2680324_fig02_38238.jpg",
"report": "Phase-contrast images of hypha development of tetracycline-regulated conditional mutants after overnight growth on agar-slide cultures containing 1% (v/v) calf serum, under repressing conditions. vac1, vam2 and vam3 showed normal hyphal development. The vac7, vac8, fab1, ykt6 and vam9 mutants formed pseudohyphae under these conditions. The asterisk indicates yeast cells at the rear of the vam3 hypha. Scale bar represents 20 μm for all images.",
"metadata": {}
},
{
"id": 664,
"image": "PMC2206024_F3_16292.jpg",
"report": "Photomicrograph of bone defect grafted with Rhizoma Drynariae extract in collagen matrix on day 14. New bone can be seen spanning the defect. Some collagen matrix (C) remained at the center of the bone defect (Periodic acid-Schiff stain; original magnification × 40).",
"metadata": {}
},
{
"id": 665,
"image": "PMC2394489_fig1_23191.jpg",
"report": "(A) Score 1. Less than 10% of the cells are stained by anti-Glut-1 (magnification × 10). (B) Score 2. Between 10 and 50% of the cells are stained with Glut-1. Strong membranous staining is seen adjacent to an area of necosis. (magnification × 20). (C) Score 3. More than 50% of cells are stained with Glut-1 at the invasive border. (magnification × 20)",
"metadata": {}
},
{
"id": 666,
"image": "PMC2405794_F2_23401.jpg",
"report": "Dual-tagged wild type and mutant GLUT4 translocates to the plasma membrane in response to insulin stimulation in 3T3-L1 adipocytes. 3T3-L1 adipocytes were transiently transfected with (a) wild type or (b) 4A mutant GLUT4HA-GFP and serum starved for 4 hr, stimulated with 83 nM insulin for 10 min then fixed for confocal microscopy as described in Materials and Methods. Green staining shows total GLUT4HA-GFP, red denotes surface exposed HA epitope.",
"metadata": {}
},
{
"id": 667,
"image": "PMC2928213_F3_72153.jpg",
"report": "Quantitative analysis of 3D trajectories on doxorubicin-treated HT1080 cells. Cells cultured during 48 h within 3D matrix or on 2D plastic were incubated with doxorubicin 0 and 5 nM for 24 h and were tracked by videomicroscopy during the last 12 h of drug incubation. Each colour on the figure corresponds to different cells (15 cells per sample). (Bar = 100 μm).",
"metadata": {}
},
{
"id": 668,
"image": "PMC2275273_F1_19682.jpg",
"report": "Clusters of goblet cells (arrow) infiltrated the muscle layer of the appendix. (Hematoxyllin and eosin). Magnification × 300.",
"metadata": {}
},
{
"id": 669,
"image": "PMC3064593_pone-0018076-g004_91074.jpg",
"report": "PlGF-1 stabilizes both AJs and TJs in vitro following VEGF-induced permeability.Representative pictures of confluent cultures of microvascular endothelial cells treated with VEGFA alone or VEGFA followed by hPlGF-1 6 hours later triple stained for VE-cadherin (red), claudin-5 (green) and nuclei (DAPI) and assessed at different times over 24 hours using confocal microscopy. VEGFA and hPlGF-1 were used at 100 ng/ml. Scale bar = 100 µm.",
"metadata": {}
},
{
"id": 670,
"image": "PMC2881047_F4_65614.jpg",
"report": "PDE4 inhibition attenuates tissue remodeling at late stage fibrosis. Representative images of lungs of healthy controls treated with vehicle (a, d) and of mice suffering from fibrosis and treated either with vehicle (b, e) or cilomilast (c, f) at days 14 (a, b, c) and 24 (d, e, f) after bleomycin administration. Hematoxilin-Eosin staining, magnification ×100.",
"metadata": {}
},
{
"id": 671,
"image": "PMC2615013_F2_32268.jpg",
"report": "Immunohistochemical studies of candidates. Representative immunohistochemical staining of normal endometrium and endometriosis tissues for the indicated proteins (AXL, SHC1, ACTN4, PI3KCA, p-AKT, p-mTOR, and p-ERK) are shown. The candidates shown exhibit increased expression of both epithelial and stromal cells of the endometriotic tissues compared to normal endometrial tissues.",
"metadata": {}
},
{
"id": 672,
"image": "PMC2797761_F1_53469.jpg",
"report": "Morphological and functional analysis of mitochondria in cells lacking α1,6-mannosyltransferase activity. (A) DASPMI staining of Kloch1-1 cells and the parental strain. (B) GFP fluorescence of mitochondrial matrix of wt and mutant strains harbouring p426SD11 mtGFP vector. (C) Mitochondrial analysis by electron microscopy of Kloch1-1 cells and the parental strain. Cultures were grown to exponential phase into YPD medium. n, nucleus; m, mitochondrion; cw, cell wall; bar 2 μm.",
"metadata": {}
},
{
"id": 673,
"image": "PMC517711_F1_485.jpg",
"report": "Areas of S1 as defined in cytoarchitectonic studies on 10 post-mortem brains [18, 19]: area 3a occupies the fundus of the central sulcus (dark blue), area 3b the anterior wall of the postcentral gyrus (red), area1 its crown (light blue) and area 2 its posterior wall (green). The black arrow indicates the central sulcus.",
"metadata": {}
},
{
"id": 674,
"image": "PMC2989377_fig3_79168.jpg",
"report": "Colonic biopsy (10x) showing changes with exudate and ulceration (arrows) that are typical of the pseudomembrane formation seen in pseudomembranous colitis.",
"metadata": {}
},
{
"id": 675,
"image": "PMC2634709_fig2_33604.jpg",
"report": "Immunofluorescence co-localisation of 8-oxo-dG and MnSOD. DAPI DNA stain (blue), 8-oxo-dG (red) and MnSOD (green). Upper panels, a tumour case with no cytoplasmic 8-oxo-dG (shows nuclear 8-oxo-dG) with abundant cytoplasmic MnSOD staining. Lower panels, represent a tumour case with abundant cytoplasmic 8-oxo-dG and MnSOD demonstrating co-localisation (yellow). Magnification × 40.",
"metadata": {}
},
{
"id": 676,
"image": "PMC3065880_fig7_91279.jpg",
"report": "Modulators of PKC activity do not affect SR-BI distribution in HepG2 cells. HepG2[eGFP-SR-BI] cells were serum starved for 4 hrs and then refed medium containing 5% FBS and either vehicle (0.1% DMSO), 0.5 μM PMA, or 7.5 μM chelerythrine chloride and incubated for 1 hr. Cells were fixed with 2.5% paraformaldehyde and imaged by confocal microscopy.",
"metadata": {}
},
{
"id": 677,
"image": "PMC516018_F2_382.jpg",
"report": "Distribution of keratin IFs and HSP70i in hepatocytes from control and GF-fed C3H mice. A, C, E keratin IFs; B, D, F HSP70i; A, B) control; C, D) 2 week treatment; E, F) 5 month treatment. Arrows in E and F indicate reactive MBs with Troma 1 (anti-K8) and anti-HSP70i, respectively. Scale bar = 20 μm.",
"metadata": {}
},
{
"id": 678,
"image": "PMC1369006_F3_4565.jpg",
"report": "Immmunohistochemical staining of SCC tumors. Immunostaining for HIF-1α (SC10790), (Santa Cruz Biotech., Inc. Santa Cruz, CA, USA) was performed on 5 μM sections. Staining was analyzed with horseradish peroxidase-linked goat antimouse (Santa Cruz Biotechnology, Santa Cruz, CA) Tumors lacking HIF-1α (top panel) and tumors that manifest an exon 12 HIF-1α polymorphism and TSC deletions in exon 36 and 40 (bottom panel).",
"metadata": {}
},
{
"id": 679,
"image": "PMC3018409_F6_83697.jpg",
"report": "3D nuclear staining of telomeres and DNA in U-HO1 RS-cells. A. Representative 2D Z-stack image no. 36 out of 80 shows ring-like multinuclear (blue) RS-cell composed of at least four nuclei of variable size. Arrow identifies a telomere group also shown in B and C. B. 3D reconstruction in surface mode reveals abundant short and very short telomeres (red). C. Combined 3D nuclear staining confirms ring-like nuclear configuration.",
"metadata": {}
},
{
"id": 680,
"image": "PMC2777157_F3_50733.jpg",
"report": "Skin biopsy on May 2008 showing dermal infiltration by a spindle cell tumour (a), which was positive with cytokeratin CAM5.2 immunohistochemical staining (b), and focally positive with Calretinin (c) and mesothelin (d) consistent with sarcomatoid mesothelioma.",
"metadata": {}
},
{
"id": 681,
"image": "PMC1988826_F1_13792.jpg",
"report": "Subcellular localization of IκBα and p65/RelA in CD4+ T lymphocytes. Cells were treated or not with 20 nM LMB and then fixed, permeabilized and stained with specific antibodies against IκBα and p65/RelA. A secondary antibody conjugated with Texas Red (Molecular Probes) was used. Images were taken by confocal microscopy.",
"metadata": {}
},
{
"id": 682,
"image": "PMC1976425_F7_13680.jpg",
"report": "Immunohistochemical localisation of MSX1 protein in bovine ovarian sections at day of estrus (b, d), day of ovulation (f, h), growth phase (j, l), dominance phase (m, q). Cumulus cells are marked with Cc and oocytes are marked with Oo. Negative controls were processed without addition of primary anti-MSX1 antibody (r, t). Sections were counterstained with toluidine blue (a, c, e, g, i, k, m, o, q and s). Images from the same ovarian sections were captured with lower and higher magnification.",
"metadata": {}
},
{
"id": 683,
"image": "PMC2820463_F3_56538.jpg",
"report": "Microscopic appearance of the lesion Focal marked nuclear pleomorphism, with isolated cells having bizarre hyperchromatic nuclei (H&E ×60)",
"metadata": {}
},
{
"id": 684,
"image": "PMC2725847_F2_43330.jpg",
"report": "Immunohistochemical identification of B cells and follicular dendritic cells in spleens of patients dying of trauma or sepsis. Total B cells are decreased in the spleen of a patient with sepsis (B) compared with that of a trauma patient (A) (magnification ×400). Similarly, follicular dendritic cells are decreased in the spleen of a patient with sepsis (D) compared with that of a trauma patient (C) (magnification ×600).",
"metadata": {}
},
{
"id": 685,
"image": "PMC2966438_pone-0013762-g002_77606.jpg",
"report": "Co-localisation of LRRK2 with ARHGEF7, CDC42 and ACTB in differentiated SH-SY5Y cells.Differentiated SH-SY5Y cells were double stained for endogenous LRRK2-CY2 and ARHGEF7-CY3, ACTB-CY3 or CDC42-CY3 and analyzed with confocal microscopy (LSM510, Zeiss). Specificity of the antibodies is indicated by immunoblotting. The specificity of the Novus 267 LRRK2 antibody is shown by means of RNAi (Figure S1). Scale bar = 10 µm.",
"metadata": {}
},
{
"id": 686,
"image": "PMC2711085_F1_41604.jpg",
"report": "Morphological reorganization of pancreatic islets from prenatal life to adulthood. We localised sympathetic nerve fibres and collagen capsules surrounding the islets by confocal microscopy in longitudinal sections of pancreases. Immunostaining for insulin (green), glucagon (blue), tyrosine hydroxylase (TH; red) and collagen type IV (2nd line, green) at different developmental stages (F19, P1, P20 and adult). Scale bar = 50 μm.",
"metadata": {}
},
{
"id": 687,
"image": "PMC2605251_pone-0004066-g009_31588.jpg",
"report": "Age-dependent effects of Fp and Fr on the morphology of reconstructed skin after grafting into nude mice.The histology of the different types of three-dimensional reconstructed skin samples was next observed 5 weeks after graft onto nude mice: (A) reconstructed skin containing young Fp; (B) young Fr; (C) old Fp; (D) old Fr. All histological sections were stained with hematoxylin, eosin, and saffron (HES). Scale bars = 50 µm.",
"metadata": {}
},
{
"id": 688,
"image": "PMC3037910_F3_86886.jpg",
"report": "GPX4 in nigral inclusions of PD brain. A. GPX4 expression (dark grey Ni-DAB, white arrowheads) coincides with AS-positive Lewy bodies (blue BCIP, marked by black arrowheads) in SN. Black arrows indicate neuromelanin. B. Confocal microscope images of two cells showing relationship of GPX4 (green) to AS (magenta). The above example shows some co-localization of GPX4 with AS within a Lewy body, while the below example shows GPX4 only around the Lewy body perimeter. Scale bars: A, 20 μm, B, 10 μm.",
"metadata": {}
},
{
"id": 689,
"image": "PMC2722669_F8_43070.jpg",
"report": "Contrasting regulation of tight junctions among VHL mutants of different disease types in RCC10. RCC10 cells lines (as indicated; all created by retroviral infection) were grown to confluence on coverslips and immunostaining for ZO-1 (left panels) was performed (original magnification of 1000×). DAPI labeled nuclei of corresponding cells are also shown (right panels).",
"metadata": {}
},
{
"id": 690,
"image": "PMC3038111_F0003_86899.jpg",
"report": "Light micrograph of control specimen with higher magnification. The RPE cells are plump-shaped and regularly arranged (arrow), (Toluidine blue × 500).",
"metadata": {}
},
{
"id": 691,
"image": "PMC2823760_F5_57154.jpg",
"report": "Case 9. The cell formations resemble Wagner-Meissner corpuscles. These are spherical and aggregated (haematoxylin and eosin staining; original magnification ×640).",
"metadata": {}
},
{
"id": 692,
"image": "PMC3060850_F3_90533.jpg",
"report": "Histopathological examination of livers. Mice that had been orally inoculated with PBS (A, B), HV-negative strain 1084 (C, D), or HV-positive strain 1112 (E, F) (in diabetic mice) (A, C, E) with inoculums of 105 CFU or in naive mice with inoculums of 108 CFU (B, D, F) were euthanized at seven days post-inoculation. Arrows indicate the area of PMN infiltration and aggregation (100 × magnification). Scale bar represents a distance of 1 μm.",
"metadata": {}
},
{
"id": 693,
"image": "PMC3016406_F1_83164.jpg",
"report": "Morphological changes in hybrid poplar suspension-cultured cells treated with TA and habituated to TA. A-D Confocal microscopy imaging of hybrid poplar cells stained with fluorescein diacetate: A treated with methanol for 24 h; B treated with TA (1.0 μM) for 24 h; C habituated to 1.7 μM TA; D TA(-)hab cells. Bar = 50 μm. E-L Electron microscopy imaging of 5-day-old non-habituated hybrid poplar cells (E and I) and 5-day-old TA(-)hab cells (F-H, J-L). n = nucleus; cw = cell wall; v = vacuole.",
"metadata": {}
},
{
"id": 694,
"image": "PMC2913988_F4_70463.jpg",
"report": "Representative MMP and TIMP protein immunodetection during the estrous cycle in Siberian hamsters. Ovarian immunohistochemical staining (dark red stain on purple/blue hematoxylin background) for all MMPs and TIMPs. (A-D) MMP-2 immunostaining, (E-H) MMP-9 immunostaining, (I-L) MMP-14 immunostaining, (M-P) TIMP-1 immunostaining, and (Q-T) TIMP-2 immunostaining. Insets show negative control immunostaining (no primary antibody present).",
"metadata": {}
},
{
"id": 695,
"image": "PMC2566591_pone-0003378-g004_28725.jpg",
"report": "A–B, Immunohistochemistry for TH in the substantia nigra.High power view (10× and 20× magnification respectively) of TH-ir neurons in the substantia nigra employing the citraconic anhydride solution. Note the enhancement in the intensity and morphology (somas more preserved and processes more delineated) compared to the conventional immunostaining method (C–D). Scale bar: A and C 100 µm; B and D 50 µm.",
"metadata": {}
},
{
"id": 696,
"image": "PMC2784772_F5_52003.jpg",
"report": "in situ hybridization analysis of Tnp2 expression during recovery after irradiation. ISH analysis of Tnp2 expression during recovery in adult mouse testis after irradiation with 1 Gy. A control, pi days 14, 24 and 38 were shown. Low magnification images of whole testis are shown (left) together with a higher magnification of a representative part of the testis (right). The bars correspond to 100 μm. ISH from additional pi days can be found in Additional file 3.",
"metadata": {}
},
{
"id": 697,
"image": "PMC1779781_F2_8768.jpg",
"report": "Imaging of location-based biosensors with subcellular resolution. A) Images of GFP-actin (top panel) and GFP-PH (lower panel) were collected from the medial section of cells using a confocal microscope. Note that GFP-PH translocated from the membrane to the cytosol in cells following UV-A exposure, but not in non-exposed (control) cells. The post-irradiation time is indicated in the images.",
"metadata": {}
},
{
"id": 698,
"image": "PMC2883150_fig1_65809.jpg",
"report": "Representative images of heterogeneous LASP-1-expression in human invasive breast cancer. Immunohistochemical staining of LASP-1 (DAB, brown, magnification × 20). (A) No LASP-1-expression (grade 0). (B) Low LASP-1-expression (grade 1). (C) Medium LASP-1-expression (grade 2). (D) High LASP-1-expression (grade 3). Arrows in (C) and (D) point to LASP-1-positive nuclei.",
"metadata": {}
},
{
"id": 699,
"image": "PMC2777141_F7_50714.jpg",
"report": "Immunostaining of SP-A. Fluorescence microscopic pictures of sections immunostained with SP-A antibody (green) and nuclear DAPI staining (blue). For fetal lung tissue (22 weeks old) (magnification 200×) (A) and hESC cultured with the ALI differentiation protocol at day 20 (VUB03_DM1 (B (magnification 400×) Pictures of sections in a perpendicular direction are shown on three different cell lines: VUB07 (C), VUB03_DM1 (D) and VUB04_CF (E).",
"metadata": {}
},
{
"id": 700,
"image": "PMC2807853_F4_55076.jpg",
"report": "Alpha-BSM® at 1 month. Masson's tricrome staining and 2× magnification of decalcified bone with calcium phosphate appearing as a still relatively compact matter. The osteoconduction process and newly formed bone were of limited grade and localized onto the interface (black arrows) between the edge of the original bone defect and the implant surface. (New bone = blue, Alpha-BSM = red)",
"metadata": {}
},
{
"id": 701,
"image": "PMC2408776_f1_23525.jpg",
"report": "Immunohistochemical characterization of primary trabecular meshwork cell cultures. Immunohistochemical assays on the TM cells were positive for fibronectin (A), laminin (B), vimentin (C), neuronal specific enolase (D) and negative for the endothelial cell marker, factor VIII (E), which indicated that the primary cultures obtained from normal and POAG individuals were indeed TM cells.",
"metadata": {}
},
{
"id": 702,
"image": "PMC2869161_fig1_64021.jpg",
"report": "Morphology of normal and tumour stromal cells. Representative microscopic fields showing normal L2N (A), L5N (C) and tumour L2T (B), L5T (D), L16T (E) P3T (F) stromal cells. Original magnification × 100 (phase contrast).",
"metadata": {}
},
{
"id": 703,
"image": "PMC2266759_F2_18785.jpg",
"report": "Maximum intensity projections of details from four of the stacks used for collection of spine data. The images are shown \"raw\" and have not undergone post-processing, such as contrast-enhancement (only rotation and resampling for screen-fit and printing purposes) (A-D). A screen shot of a three-dimensional (3-D) animation of one of the analyzed dendrites illustrates the 3-D advantage of the method (E). The letters t, m and s exemplify thin, mushroom and stubby spines, respectively.",
"metadata": {}
},
{
"id": 704,
"image": "PMC2170428_fig06_15732.jpg",
"report": "Requirements of supplemental iron for biofilm formation and synthesis of C56–C68 fatty acids. M. smegmatis biofilms were grown for 4 days, with supplemental ferric iron induced in the following concentrations: none (A), 0.5 μM (B), 1 μM (C), 2 μM (D) and 5 μM (E). Samples were harvested, mycolic acids extracted, and analysed by MALDI-TOF as shown in the right. The position of the series of C56–C68 fatty acids is indicated above.",
"metadata": {}
},
{
"id": 705,
"image": "PMC2650710_F1_35338.jpg",
"report": "Micrographs of immunohistochemistry on two breast cancer cryostat sections showing immunoreactivity of Gb3 (redbrown), in (A-C) tumour cells and (D) vascular vessels. 40× magnification.",
"metadata": {}
},
{
"id": 706,
"image": "PMC1164403_F1_2369.jpg",
"report": "Examples of the different immunostaining patterns obtained using the antibody clones 22-1-1 and Ab-1 in normal glandular tissues. Mucosa of the corpus of stomach (a, b; magnification × 10) and (c, d; magnification × 45). Colonic mucosa (e, f; magnification × 25), (g; magnification × 60) and (h; magnification × 50). Prostatic glands (i; magnification × 60) and (j; magnification × 50).",
"metadata": {}
},
{
"id": 707,
"image": "PMC2816995_pone-0009054-g006_56230.jpg",
"report": "Double staining of BrdU and vGluT mRNA.(A, B) Confocal images of sections dually stained by anti-BrdU antibody (green) and an antisense riboprobe against vGluT mRNA (red). Nuclei were stained with DAPI (blue). Arrows indicate BrdU-positive nuclei surrounded by a vGluT signal as demonstrated by in situ hybridization. (C, D) No signal is detected by a sense probe against vGluT mRNA. Magnifications of objective lenses were 63× (A, C) or 100× (B, D). Scale bars: 20 µm.",
"metadata": {}
},
{
"id": 708,
"image": "PMC3083698_f2-ijms-12-01175_93590.jpg",
"report": "Scanning electron microscope (SEM) observations of the biofoam. (a) and (b), The 1% biofoam exhibits filaments; (c) and (d), the 4% biofoam presents a leaf-based structure.",
"metadata": {}
},
{
"id": 709,
"image": "PMC1952073_pone-0000844-g007_13318.jpg",
"report": "Live cell confocal microscopy confirms NDRG1 involvement with recycling E-cadherin.Live cell confocal images of stable NDRG1DsRed2-HEK293 cells transfected transiently with E-cadherinEGFP construct and plated in calcium-supplemented media after being chelated with EDTA shows NDRG1DsRed2 positive vesicles interact with recycling E-cadherinEGFP both near the perinuclear space and close to the membrane. The image is a still from Movie S4.",
"metadata": {}
},
{
"id": 710,
"image": "PMC1804283_F1_9710.jpg",
"report": "Cellular model of hepatic fibrosis. (A) Morphological changes of M1-4HSCs treated with TGF-β1 either for 72 hours or for long-term (myofibroblastoid M-HT) as analyzed by phase contrast microscopy. (B) Nuclear translocation of Smad2/3 as visualized by confocal immunofluorescence analysis. (C) Confocal immunofluorescence images after staining of cells with anti-desmin antibody.",
"metadata": {}
},
{
"id": 711,
"image": "PMC2816659_fig5_56166.jpg",
"report": "Fluorescent images of cells overexpressing class III β-tubulin after drug exposure. MCF-7-control, MCF-7-TUBB3, MDA-MB-231-control and MDA-MB-231-TUBB3 cells were treated for 48 h with STX140, paclitaxel or colchicine at concentrations close to IC50 values obtained in control cells and stained with FITC-anti-tubulin (tubulin) and Hoechst 33342 (nucleus). Images were taken using a Zeiss inverted microscope at × 200 magnification.",
"metadata": {}
},
{
"id": 712,
"image": "PMC2650704_F1_35334.jpg",
"report": "Vascular defects in Snai1-cko embryos. (a-d) PECAM-1 immunostained E8.5 littermate control (a) and Snai1-cko (b-d) embryos. (d) Higher magnification view of the dorsal region of a different embryo showing endothelial cell aggregates (arrow). (e, f) VE-cadherin immunostained E8.5 control (e) and Snai1-cko (f) embryos. Asterisks indicate discontinuous vessels, and arrows point to isolated aggregates of PECAM-1 positive cells.",
"metadata": {}
},
{
"id": 713,
"image": "PMC3025950_F5_85381.jpg",
"report": "Expression of hematopoietic markers in HD cells following HIV infection. Immunohistochemistry of HD-HIV cells, fluorescent images indicate the expression of CCR5, CCR4, NOS2, and CXCR4. Right panel shows the DIC images of identical fields. Images were obtained with Leica TCS SP-2 confocal microscope. Scale bar 10 μm.",
"metadata": {}
},
{
"id": 714,
"image": "PMC2360755_fig2_21354.jpg",
"report": "Tumour vascular destructive effect and haemorrhagic necrosis upon Hi-based ILP. Pictures of representative tumour histology (HE) and vascular destruction (CD31) right after ILP with DXR, Hi or DXR + Hi are shown. Orange bar on × 16 magnification pictures corresponds to 100 μm and red bar on × 40 magnification to 50 μm.",
"metadata": {}
},
{
"id": 715,
"image": "PMC1808440_F5_9810.jpg",
"report": "Histiocytic sarcoma. Residual follicular dendritic cells are strongly positive for CD21. (B-SA, anti-CD21, original magnification × 200).",
"metadata": {}
},
{
"id": 716,
"image": "PMC2944848_pone-0012941-g002_74451.jpg",
"report": "Hepatic formation and clustering of foamy macrophages in NPC1 knockdown mice.Masson's trichrome stained liver sections from mice injected for 9 weeks with mismatched (MM) and NPC1-specific ASOs and subjected to treatment with saline or anti-TNF. Images were photographed at 200X magnification.",
"metadata": {}
},
{
"id": 717,
"image": "PMC1557511_F3_6819.jpg",
"report": "Absence of ChAT in embryonic mouse ovary and morphology of ChAT (-/-) mouse ovary. A: ChAT is not detectable using immunohistochemical methods in a mouse ovary at day 18 p.c. Bar = 50 μm. B-C: H.E. stained sections of the ovary of an embryonic (day 18 p.c.) age-matched wild-type ovary (+/+) and a mutant mouse null for ChAT (-/-). Bars = 60 μm.",
"metadata": {}
},
{
"id": 718,
"image": "PMC2683874_F15_38678.jpg",
"report": "Correlation between drug targeting and betweenness of nodes. yFiles Circular Layout of AM network that emphasizes the nodes with high betweenness. The nodes with high betweenness are localized on the left half of the circle (blue colour and highest density of the edges). These proteins are characterized by their propensity to be drug targets, as shown with the major size of nodes.",
"metadata": {}
},
{
"id": 719,
"image": "PMC2861660_F2_63163.jpg",
"report": "Immunohistochemical staining of porin, complex II and complex III of NB, adjacent adrenal cortex and adrenal medulla. Immunohistochemical staining of porin (a, d, g), complex II subunit 70 kDa Fp (b, e, h) and complex III subunit Core2 (c, f, i) in unaffected adrenal tissue (a, b, c) and unaffected adrenal medulla (d, e, f) was compared to the adjacent NB tumor tissue (g, h, i). Magnification: Figure 2a - c 200×, Figure 2d - i 400×.",
"metadata": {}
},
{
"id": 720,
"image": "PMC2823169_F0002_57010.jpg",
"report": "Morphological evaluation of periprosthetic biopsies. A. Minimal debris and no significant reaction; H and E staining, ×10. B. Significant debris mostly within macrophages; H and E staining, ×20. C. Massive debris and extensive reaction; H and E staining, ×10. D. Macrophages filled with alumina particles at higher magnification; H and E staining, ×60.",
"metadata": {}
},
{
"id": 721,
"image": "PMC2805894_F0002_54731.jpg",
"report": "Scan pattern of trabecular (t) and marrow space (l) path lengths",
"metadata": {}
},
{
"id": 722,
"image": "PMC1513245_F8_6089.jpg",
"report": "Representative sections of mammaglobin A (SCGB2A2) protein expression as detected by immunohistochemistry. A: Mammaglobin A expression found in invasive ductal carcinoma. B: Mammaglobin A expression in invasive lobular carcinoma. C: Mammaglobin A expression in squamous cell carcinoma of the cervix. D: Mammaglobin A expression in an endometrioid adenocarcinoma of the endometrium. Note that mammaglobin A is not expressed equally in all cells. Magnification: 400 ×.",
"metadata": {}
},
{
"id": 723,
"image": "PMC2800773_pone-0008674-g002_53665.jpg",
"report": "Chicken antibody detects PAP in mouse DRG neurons and dorsal spinal cord.(A–D) Sections from mouse L4-L6 DRG and (E–L) lumbar spinal cord were stained with chicken anti-PAP antibodies (red) and with antibodies against various sensory neuron markers and spinal interneuron marker PKCγ (blue, green). (D, H, L) Merged images. All images were acquired by confocal microscopy. Scale bar in (D) 50 µm, (H) 100 µm.",
"metadata": {}
},
{
"id": 724,
"image": "PMC2956457_fig7_76165.jpg",
"report": "Double fluorescence immunolabeling (green signal: anti-c-kit Ab; red signal anti-insulin Ab) under confocal laser microscopy of NPI cell monolayers cultivated for 7 (a), (d), 14 (b), (e), and 21 (c), (f) days, alone (a)–(c) or with SC (d)–(f). Bar =10 μm.",
"metadata": {}
},
{
"id": 725,
"image": "PMC548140_F2_1242.jpg",
"report": "No significant apoptosis was found in TIIcells upon hyperoxia in vivo for 48 hrs. Lung tissue of normoxic rats (left) and of hyperoxic rats (right) were tested for DNA fragmentation by TUNEL reaction as described in Materials and Methods. The positive TUNEL reaction is represented by green fluorescence. The presence of lamellar bodies is indicated by red fluorescence. Pseudo-colour blue was used to highlight the contours of lung tissue. Bar: 25 μm.",
"metadata": {}
},
{
"id": 726,
"image": "PMC2364801_fig3_21759.jpg",
"report": "Examples of an invasive (A) and a practically noninvasive (B) tumour in a brain slice. Each of the two image montages is composed of six contiguous microscopic fields (× 100, 0.76 mm2). To avoid out-of-focus fluorescent glow and to facilitate tumour cell recognition, each image of glioma cells was separately segmented using grey morphology and adaptive thresholding algorithms (KS400 3.0), and the resulting binary image was overlaid in grey.",
"metadata": {}
},
{
"id": 727,
"image": "PMC2394393_fig4_23182.jpg",
"report": "β-catenin expression in oral squamous cell carcinoma. (A) An oral squamous cell carcinoma shows preserved β-catenin expression, original magnification × 170; (B) An oral squamous cell carcinoma shows reduced β-catenin expression, original magnification × 170.",
"metadata": {}
},
{
"id": 728,
"image": "PMC2375213_fig5_22280.jpg",
"report": "H&E staining of sections from Panc-1 (A), Panc-1/BAI11 (B), and Panc-1/LacZ 1 (C) tumours (magnification, ×10). Large areas of necrosis in the Panc-1/BAI1 tumour samples. Also, the expression of the endothelial cell marker CD31 in human Panc-1 (D), Panc-1/BAI11 (E), and Panc-1/LacZ (F) tumours from immunodeficient mice (magnification,×40) showed a decreased vascular index (G) in the BAI1 transfectant tumour samples.",
"metadata": {}
},
{
"id": 729,
"image": "PMC2803165_F6_53987.jpg",
"report": "Early carcinoma (H&E, oil immersion, 400-fold magnification).",
"metadata": {}
},
{
"id": 730,
"image": "PMC3048549_F2_88958.jpg",
"report": "The histological and immunohistochemical examinations of the patient with ACD. (A) H&E staining indicated hyperkeratotic epidermis and amorphous eosinophilic masses in the papillary dermis. (original magnification × 40). (B) Congo red staining indicated positive for eosinophilic masses. (original magnification × 100). (C) The immunohistochemical examination indicated negative for HMB-45. (original magnification × 100)",
"metadata": {}
},
{
"id": 731,
"image": "PMC1831740_pmed-0040108-g005_10130.jpg",
"report": "\nOLIG1 Immunohistochemistry on a Lung Tissue Array\nOLIG1 immunohistochemistry on (A and E) tumor-free lung, (B) an OLIG1 negative adenocarcinoma, and (F) an OLIG1 negative SCC; (C) a low OLIG1 expressing adenocarcinoma and (G) a low OLIG1 expressing SCC are shown; (D) a high OLIG1 expressing adenocarcinoma and (H) a high OLIG1 expressing SCC are shown. All images were acquired at 400× magnification.",
"metadata": {}
},
{
"id": 732,
"image": "PMC2748705_pone-0007243-g003_46649.jpg",
"report": "500 nm magnifications of minichromosomes assembled without or with each somatic H1.The same techniques as in Figure 2 were used. The horizontal bar corresponds to 100 nm and the grid size is 500 nm. The vertical scale is shown.",
"metadata": {}
},
{
"id": 733,
"image": "PMC2777305_pone-0007986-g007_50818.jpg",
"report": "MSP142 co-localizes with fetal endothelial cells following perfusion.MSP142 (green staining) co-localizes with CD31 (PECAM-1, red staining) indicating its presence in and around the fetal vascular endothelial cells (upper and lower panels for placentas 1 and 5 respectively). Similar co-localization was observed for placentas 2 and 3 (not shown). The upper panels are at 400× and lower at 200× magnification.",
"metadata": {}
},
{
"id": 734,
"image": "PMC2824845_fig1_57416.jpg",
"report": "Time-lapse imaging of YFP–CBP. HEK293 cells were transfected with 1 μg pEYFP–CBP expression plasmid. Image capture was initiated approximately 14 h post-transfection at 5 min intervals for 4 h. The images shown were deconvolved and merged to produce the composite images. The insets in the top left hand corner show a higher magnification of the selected region, highlighting the formation of CBP-containing nuclear bodies and their relative migration during the experiment.",
"metadata": {}
},
{
"id": 735,
"image": "PMC2945357_F2_74636.jpg",
"report": "The coumarin dyes are fixable. Zebrafish larvae at 6 dpf were stained with BODEC (A) or DIBPBC (B) and fixed in 4% paraformaldehyde. The retinas were sectioned and visualized by confocal laser scanning microscopy. The zebrafish retinas are clearly visualized similar to the in vivo imaging.",
"metadata": {}
},
{
"id": 736,
"image": "PMC2996806_f3-ijms-11-03922_80446.jpg",
"report": "Scanning electron micrographs of P. aeruginosa incubated with the optimum concentration of ethanolic leaf extract of Perilla frutescens var. acuta (A) Control (absence of extract); (B) disruption and lysis of membrane integrity; (C) wrinkled abnormalities and cleft formation; (D) abnormal breaking of cell.",
"metadata": {}
},
{
"id": 737,
"image": "PMC2839371_fig4_59317.jpg",
"report": "Demonstration of cellular details in the soft tissue region of articular cartilage. (a) Original sliced data, (b) 10× digitally magnified (median-filtered) region of a lacuna doublet with their chondrocytes in the centres, (c) correspondence with SEM/FIB and (d) rendering of the 10× magnified data and volume estimation for the frontal lacuna (three-dimensional reconstruction).",
"metadata": {}
},
{
"id": 738,
"image": "PMC1762394_pone-0000023-g006_8212.jpg",
"report": "Mice bearing microscopic NB-1643 tumors were injected intravenously with 2 million HB1.F3.C1 cells pre-labeled with CM-DiI Red Cell Tracker.Normal and tumor-bearing organs were harvested, sectioned, and stained with DAPI. HB1.F3.C1 cells were not detected in normal (A) brain, (B) kidney, (C) heart, (D) intestine, or (E) skin tissue.Rare, single, HB1.F3.C1 cells (white arrows) were seen in (F) lung, (G) liver and (H) spleen.Scale bars: 200 µm (A–E), 100 µm (F–H).",
"metadata": {}
},
{
"id": 739,
"image": "PMC2606030_pone-0004104-g004_31711.jpg",
"report": "Pqbp-1.1-Venus fusion protein expression in adult nematode.Expression in the pharynx decreases. Intestinal cells keep a high expression level of pqbp-1.1-Venus in adult worms. Arrowheads indicate intestinal cells. Somatic gonads show no expression of pqbp-1.1-Venus. In the tail region, fluorescence was detected in several neurons (arrows).",
"metadata": {}
},
{
"id": 740,
"image": "PMC1868920_F1_10895.jpg",
"report": "FGFR1 gene amplification in breast cancer. (a) Grade 3 invasive ductal carcinoma (haematoxylin and eosin; original magnification × 200) with (b) one or two copies of FGFR1 (original magnification × 400; inset: × 630). (c) Grade 3 invasive ductal carcinoma (haematoxylin and eosin; original magnification × 200) harbouring (d) FGFR1 gene amplification (original magnification × 400; inset: × 630).",
"metadata": {}
},
{
"id": 741,
"image": "PMC2920267_F6_71127.jpg",
"report": "Cellular ultrastructure following HG treatment. Transmission electron microscopy depicts the change in cellular ultrastructure following HG (30 mM) exposure (magnification × 6,000). It can be seen that normal HAECs present with few microfilaments and a rough endoplasmic reticulum (A). After exposure to HG, microfilamentation and a swollen rough endoplasmic reticulum appeared in the cytoplasm (B). These changes were attenuated by treatment with irbesartan (C). 1 bar = 4 μm.",
"metadata": {}
},
{
"id": 742,
"image": "PMC2601018_f1-co15-6-293_31251.jpg",
"report": "Hepatic biopsy showing normal liver in lower quadrant, with neoplastic clusters (arrows) of metastatic squamous cell carcinoma (hematoxylin and eosin stain, 20x× magnification).",
"metadata": {}
},
{
"id": 743,
"image": "PMC2628312_f6_32673.jpg",
"report": "In situ hybridization of MUC4 and MUC5AC mRNA. MUC5AC mRNA decreased (D) and MUC4 mRNA (B) increased expression in the conjunctiva of transgenic mice compared with those of their control littermates (A and C). Magnification, 200X.",
"metadata": {}
},
{
"id": 744,
"image": "PMC2912868_F5_70302.jpg",
"report": "Ultrastructural characterization of sarcomeres in ultrathin cross-sections of TA from control (top) and tumor-bearing (bottom) mice observed by transmission EM. A disarrangement of the myofilament hexagonal organization at the level of the A-band is observed upon tumor burden. Bar = 250 nm.",
"metadata": {}
},
{
"id": 745,
"image": "PMC2360640_fig3_21312.jpg",
"report": "Immunohistochemical analysis of CD70 in RCCs. CD70 expression throughout the carcinoma tissues of frozen sections of clear cell RCC (ccRCC) is shown (panels i–iii) relative to an isotype matched control antibody (panel iv). CD70 expression was not seen in normal kidney tissues (panel v). Panels i–v all show images at × 20 magnification. Panel vi shows a higher power (× 40) image of a CD70-positive ccRCC tissue demonstrating the plasma membrane expression of CD70 in the carcinoma cells.",
"metadata": {}
},
{
"id": 746,
"image": "PMC2763286_pgen-1000712-g003_48199.jpg",
"report": "Electron microscopic observation of morphology for sperm maturation in testis and epididymis.The head-tail junction in testicular sperm of wild-type (A) and OAZ-t null mutant (B) is shown. The sperm tail in the homozygous OAZ-t mutant epididymis (C,D) was improperly arranged at the head tail junction. Arrows indicate the abnormal head-tail jounction. Bar = 1.0 µm (A–D).",
"metadata": {}
},
{
"id": 747,
"image": "PMC2973936_F1_78000.jpg",
"report": "Derivation of clonal hAFS cell lines by the starter cell method. (A) and (B) A hAFS starter cell of fibroblastic type (arrow) was found early after a routine amniocentesis culture, (C) the colony appearance of a clonal hAFS cell line at 48 h in the primary culture dish, (D) morphology of hAFS cells derived by the starter cell method at subculture passage 3.",
"metadata": {}
},
{
"id": 748,
"image": "PMC2952819_fig10_75611.jpg",
"report": "PAS staining of 5 μm-thick left lobe lung sections from (a) C57Bl/6 filtered air-exposed, (b) C57Bl/6 OVA-exposed, (c) NOS1−/− OVA-exposed, and (d) NOS3−/− OVA-exposed mice. Images were taken at 400× magnification.",
"metadata": {}
},
{
"id": 749,
"image": "PMC3080330_F6_92960.jpg",
"report": "Immunohistochemical staining for DNMTs in 125I seed implanted pancreatic cancer. Representative staining sections for DNMT1 (upper), DNMT3b (middle) and DNMT3a (lower) were prepared as described in the Materials and Methods section. The brownish yellow spots represent positive staining. Scale bars represent 500 μm.",
"metadata": {}
},
{
"id": 750,
"image": "PMC3040871_F0001_87566.jpg",
"report": "Scanning Electron MicrophotographsScanning electron microphotographs of plain mannitol (a), aceclofenac-loaded proliposomes was recorded at 60 X magnifications (b) and at 200 X magnification to characterize surface properties of the proliposomes (c).",
"metadata": {}
},
{
"id": 751,
"image": "PMC2895884_F0004_68057.jpg",
"report": "Ovoid pseudo-fungal structures among a) acellular debris with b) some that appear to have a cell wall and c) others that appear unencapsulated. (Pap stain; original magnification ×600).",
"metadata": {}
},
{
"id": 752,
"image": "PMC2793897_f3_52920.jpg",
"report": "Two-dimensional dichlorofluorescein fluorescent photomicrographs of as human corneal endothelial cells. The cells revealed higher intensity of fluorescence at higher concentrations of tert-Butyl hydroperoxide (tBHP). The clusterin-treated group showed lower dichlorofluorescein (DCF) fluorescence, compared to the control.",
"metadata": {}
},
{
"id": 753,
"image": "PMC1848005_F5_10317.jpg",
"report": "Photograph showing resected tumour with eyeball exenteration.",
"metadata": {}
},
{
"id": 754,
"image": "PMC1112617_F1_2192.jpg",
"report": "LMP1 immunostaining on tissue sections of NPC samples. A. Intense and diffuse LMP1 expression in an NPC biopsy from a 47 year old patient (score 12, 400X) B. Intense LMP1 expression in a limited area in an NPC biopsy from a 17 year old patient (score 7, 600X) C. Moderate and diffuse LMP1 expression in an NPC biopsy from a 44 year patient (score 8, 400X) D. Absence of LMP1 expression in a lung carcinoma biopsy (score 0, 600 X)",
"metadata": {}
},
{
"id": 755,
"image": "PMC2964634_F5_77028.jpg",
"report": "Histopathology results. [A] Representative H&E section of WT mammary carcinoma, as reviewed by pathologist. [B] Premalignant lesion (DCIS) in a KO mouse. [C] Photomicrograph of H&E section of KO mammary carcinoma, as reviewed by pathologist. ** denotes invasion into muscle. Magnification × 400.",
"metadata": {}
},
{
"id": 756,
"image": "PMC2760782_pone-0007497-g002_47861.jpg",
"report": "Contrast enhancement by standard deviation projection of bright field image stack.(A) Low contrast bright field image. (B) Fluorescence staining for whole cell and bright spot detection. (C) Standard deviation projection of stack of bright field images. (D) Inverse of the projection for another visualization of the projection result. In addition to increased contrast, the projection also suppresses background nonuniformities.",
"metadata": {}
},
{
"id": 757,
"image": "PMC2375427_fig1_22369.jpg",
"report": "(A) Presence of C-cell hyperplasia in the peritumoural tissue of a radiation-induced thyroid tumour (T) of patient Ti226 (×100 magnification). The arrows indicate calcitonin positive C-cells. (B) The same C-cell hyperplasia seen with ×250 magnification. The calcitonin C-cells was detected by immunohistochemistry using a polyclonal anti-calcitonin antibody.",
"metadata": {}
},
{
"id": 758,
"image": "PMC1769400_F2_8492.jpg",
"report": "Histochemical and immunohistochemical staining in muscle biopsies from AR-LGMD patients. Hematoxylin and eosin (H&E) staining (panel A), dystrophin expression (panel B), and emerin detection (panel C).",
"metadata": {}
},
{
"id": 759,
"image": "PMC2880141_F3_65446.jpg",
"report": "Large area of hemorrhage (left side), necrosis (right and bottom) and calcification (right and upper side), original magnification ×100.",
"metadata": {}
},
{
"id": 760,
"image": "PMC2682800_F4_38538.jpg",
"report": "Deconvolution fluorescence imaging of Oct-4 mRNA and total mRNA in live P19 cells, with cell nucleus stained with Hoechst 33342 (blue). A. The cytosolic localization of Oct-4 mRNA (red) in undifferentiated (UD) and RA treated (differentiated) cells. B. Total RNA staining using SytoRNA Select dye (green) in undifferentiated (UD) and RA treated (differentiated) cells. Scale bar = 15 μm.",
"metadata": {}
},
{
"id": 761,
"image": "PMC2364187_fig4_21696.jpg",
"report": "Bright field image of HCT116+ch3 (A) and HCT116+ch2 (B) after incubation with 0.1 μg ml−1 m-THPC for 24 h. After 24 h of incubation there was no detectable fluorescence within the nucleus. The nuclear membrane is distinctly stained in both cell lines.",
"metadata": {}
},
{
"id": 762,
"image": "PMC2265766_pbio-0060051-g004_18745.jpg",
"report": "Dynamic Redistribution of EYFP-Tagged CK-B during Phagocytosis.Time-lapse microscopy of zymosan (A and D), COZ (B and E), or IgG-opsonized zymosan (C and F) uptake in RAW 264.7 cells stably transfected with EYFP-CK-B (A–C) or EYFP (D–F). Photos represent a single frame at the peak of accumulation from a time-lapse recording; arrows mark the start of the corresponding line plot visualizing accumulation of signal in the cup. Bars indicate 10 μm.",
"metadata": {}
},
{
"id": 763,
"image": "PMC2682575_pone-0005655-g005_38458.jpg",
"report": "Reconstruction of dendrites of cortical pyramidal neurons.A. Dendrites of two pyramidal neurons were reconstructed together with part of the cell bodies from an image stack that contained many en passant neural processes. Reconstructed neurons were superimposed on the maximum-intensity projection of the entire image stack. B. 3D rendering of the two reconstructed neurons. Scale bar: 10 µm.",
"metadata": {}
},
{
"id": 764,
"image": "PMC2769429_fig-002_49485.jpg",
"report": "Microscopic findings of non-caseous epithelioid granulomatous lesion. (A): High-power view of the nodule revealed epithelioid cells and multinucleated giant cells with droplets (arrows) and infiltration of eosinophils and lymphocytes (HE, X400). (B): Immunohistochemical staining for CD-68. Epithelioid cells and multi-nucleated giant cells were positive for CD-68. (C): Immunohistochemical staining for CD-3. (counterstained with Hematoxylin, X400).",
"metadata": {}
},
{
"id": 765,
"image": "PMC2946336_pone-0013002-g001_74816.jpg",
"report": "Morphologies and clustering of selected pancreatic cancer cell lines.Mesenchymal-like cell lines are presented in the top two rows, and epithelial-like cell lines are in the bottom two rows. Note the increased cell scatter and spindle like projections seen in the mesenchymal-like cells as compared to the tighter cell-cell adhesion and more spherical shape characteristic of the epithelial cells. The images were collected by phase-contrast microscopy at 10× magnification.",
"metadata": {}
},
{
"id": 766,
"image": "PMC3051128_F0006_89447.jpg",
"report": "Osteochondral loose body, consisting mainly of central cartilaginous material with focal endochondral ossification and covered with a layer of fibrotic synovial membrane. Attenuated synovial cells are present on the surface (Haematoxylin and Eosin stained section, original magnification ×5 objective)",
"metadata": {}
},
{
"id": 767,
"image": "PMC2920310_pone-0012084-g003_71138.jpg",
"report": "Measured values of intracellular electric fields using nanovoltmeters.Figure from Tyner, et al. (ref [20]). (A) E values shown as continuous tone intensity. (B) E values in the 10 boxes of A. Note that values of E generally decrease with distance from the NM. Regions 5 and 6 correspond to a bright spot similar to the mitochondrion shown higher in the image and so likely reflect the local influences of the charge in the mitochondrial membrane.",
"metadata": {}
},
{
"id": 768,
"image": "PMC2936387_F6_73184.jpg",
"report": "Syncytin-1 but not MSRV Env, Xq22.3 Env FLΔStop, or Xq22.3 Env induces syncytia in HeLa cells. HeLa cells were transfected with the indicated HERV-W Env constructs and subsequently stained with May-Grünwald and Giemsa solutions to visualize syncytia formation. Multinucleated giant cells (syncytia) were only detectable in cells transfected with Syncytin-1. Magnification × 250.",
"metadata": {}
},
{
"id": 769,
"image": "PMC2941740_F1_74041.jpg",
"report": "Particle morphology of FeCr, FeSiCr, 316L, Fe, Cr, and Cr2O3 by means of BE-SEM. SEM images of different magnification showing the morphology of the different particle types, with a) FeCr coarse (representative for FeCr fine and FeCr dust as well), b) FeSiCr fine (representative for FeSiCr coarse and FeSiCr dust as well), c) 316L coarse (representative for 316L fine as well), d) Fe coarse (as Fe fine), e) Cr coarse (as Cr fine), and f) Cr2O3.",
"metadata": {}
},
{
"id": 770,
"image": "PMC1939715_F1_12683.jpg",
"report": "The localization of prolactin receptor in the liver was evaluated by immunohistochemistry (scale bar = 50 μm) in liver sections from normal and BDL female and male rats. Bile ducts from normal and BDL female and male rats express these receptors (arrows). No immunohistochemical reaction was observed when a consecutive liver section of the same field was incubated with non-immune serum. Hepatocytes from normal and BDL female and male rats express the prolactin receptor.",
"metadata": {}
},
{
"id": 771,
"image": "PMC3016508_F0003_83182.jpg",
"report": "Histopathological features of colitis in common variable immunodeficiency. Colon biopsy showing (a) acutely inflamed colonic tissue and colonic mucosa with chronic colitis. (b) Chronic colonic crypt damage manifested as branching, tangential alignment and increased amount of chronic inflammatory cells and absence of plasma cells and giant granuloma",
"metadata": {}
},
{
"id": 772,
"image": "PMC2954839_F5_75903.jpg",
"report": "Histopathological examination. Monomorphic tumor cells arranged around thin-walled vessels (Hematoxilin and Eosin, magnification × 200).",
"metadata": {}
},
{
"id": 773,
"image": "PMC2891638_F2_67233.jpg",
"report": "Immunohistochemical analysis of DAB2 expression in NPC. (A) Surface epithelium of ovary served as positive control (original magnification × 400). (B) Normal nasopharyngeal epithelium (× 400). Arrows indicate the positive epithelium. (C) Cytoplasmic staining in a NPC biopsy (× 200). Arrows indicate positive NPC cells. (D) Negative staining in NPC cells. The dendritic cells (arrows) in the stroma served as internal positive controls (× 200).",
"metadata": {}
},
{
"id": 774,
"image": "PMC2906155_fig2_69160.jpg",
"report": " Immunohistochemical studies on Fut8, GnT-V, and GPC3 in thyroid cancer. The staining of Fut8 was located in the Golgi apparatus, while GnT-V staining was observed throughout a cell. Staining of GPC3 was heterogeneous and showed a membrane pattern. ",
"metadata": {}
},
{
"id": 775,
"image": "PMC2714591_F3_42056.jpg",
"report": "3D structure models of proteins. Models for proteins WAH-1 (modeled amino acids 238–700 of 700), CPS-6 (modeled amino acids 57–305 of 308), and endoG (modeled amino acids 65–296 of 297) were calculated using Phyre server. Model of HSP70-1 (modeled amino acids 1–554 of 641) was calculated by server M4T. Structures were visualized using UCSF Chimera software.",
"metadata": {}
},
{
"id": 776,
"image": "PMC2667491_F3_37113.jpg",
"report": "Orthotopic NB tumors at autopsy after treatment with CHS 828 or vehicle. Orthotopic tumors at autopsy treated with vehicle or CHS 828 (20 mg/kg/day) for 10 or 30 days. Note the brown color of the tumor after 10 days of treatment, indicating areas of resorbed hemorrhage. T = tumor, RK = right kidney, LK = left kidney; arrows indicate the normal right adrenal gland.",
"metadata": {}
},
{
"id": 777,
"image": "PMC2997767_F3_80526.jpg",
"report": "Tumor vascular complexes showing [a] GFAP positivity in the perivascular layers 1&2 [mAbGFAPX400]; [b] NFP positivity in layers 4 & 5 [mAbNFPX400]; and [c] Syn positivity in layer 5 [mAbSynX100]. The cells in the perimantle zone show a high percentage of NFP & Syn +ve cells and a low percentage of GFAP +ve cells. [d] Syn positive cells in L4&L5 [mAbSynX1000] showing dendritic processes resembling primitive neurons. Camera Lucida CL diagrams are shown to highlight the positive cells.",
"metadata": {}
},
{
"id": 778,
"image": "PMC1819384_F5_9956.jpg",
"report": "Electron microscopy analysis of structure changes in E. coli challenged baboon lung. a: normal architecture of the alveolar septae in healthy baboons; b. accumulation of neutrophils (PMN) and the presence of intra-alveolar bleeding erythrocytes (arrow) can be observed at 2 hrs; c: the increased accumulation of macrophages, fibroblasts and collagen deposition at 24 hrs. av, alveola; coll, collagen; Fb, fibroblasts; Mac, macrophages; RBC, red blood cells. Magnification: ×7000.",
"metadata": {}
},
{
"id": 779,
"image": "PMC1847813_F3_10298.jpg",
"report": "Expression and stability of full length and truncated NCOA7 proteins in E. coli. Cells were either induced or not with IPTG. Proteins from induced or uninduced exponential phase cells were labeled with 35 [S] Met and chased, then harvested either immediately, or after 15, or 30 min further incubation as indicated in the figure. The arrows indicate the positions of the full length and truncated (657–942) forms of NCOA7 protein.",
"metadata": {}
},
{
"id": 780,
"image": "PMC2821930_pone-0009242-g005_56753.jpg",
"report": "Meiosis in male Mcph1gt/gt germ cells.(A) Section of a testes biopsy from a male Mcph1gt/gt showing normal morphology, (B) diakinesis/metaphase I from a male Mcph1gt/gt reveals normal pairing of the autosomal bivalents and the sex chromosomes (XY), (C) normal metaphase II cell from a male Mcph1gt/gt. For comparison a diakinesis/metaphase I (D) and a metaphase II cell (E) from a male wt/wt mouse are presented.",
"metadata": {}
},
{
"id": 781,
"image": "PMC2180180_F3_15915.jpg",
"report": "Conidia production of Paracoccidioides brasiliensis in Soil Extract Agar, exhibiting the conidia production of the isolates D01 and T9B1 cultured in soil extract agar (SEA) and prepared through adhesive tape technique (magnification ×1000).",
"metadata": {}
},
{
"id": 782,
"image": "PMC2838809_F8_59181.jpg",
"report": "Electron micrographs illustrating liver cells from control (A and D) fasten (B and D) and fed restricted (C and E) rats. Notice that hepatocytes from the fed restricted animal (F) exhibit electron-dense mitochondria (m) surrounded by abundant smooth endoplasmic reticulum (SER). N = cell nucleus, gl = glycogen, asterisks = lipid droplets, arrows = bile canaliculi. Lead-uranium staining. Scale bars = 2 μm in A-C; 0.2 μm in D-E. Representative images of 6 independent experimental observations.",
"metadata": {}
},
{
"id": 783,
"image": "PMC2652113_pgen-1000413-g002_35510.jpg",
"report": "\nbbp embryos constrict at the margin at 50% epiboly, bursting the yolk.Still images of WT and bbp embryos at the 1000-cell stage (A, B), 50% epiboly (A′, B′), and 50% epiboly at the burst (A″, B″). bbp embryos constrict just as they reach 50% epiboly. (C and D) Selected frames from time-lapse movies of WT and bbp embryos showing that the constriction occurs rapidly once the embryos have reached 50% epiboly.",
"metadata": {}
},
{
"id": 784,
"image": "PMC2797518_F2_53321.jpg",
"report": "Comparison of some microscopic observations. LB = Lactobacilli; BG-: Gram-negative bacilli; DC+: Gram-positive diplococci; Y: yeast cell; VS: Vaginal Swab; CS: Cervical swab.",
"metadata": {}
},
{
"id": 785,
"image": "PMC2709657_F3_41516.jpg",
"report": "Extreme size dimorphism between a) large diploid and small haploid eggs and b) the resulting triploid and diploid tadpoles from female F11. Scale in cm. (The tadpoles were only temporarily in the petri dish for photographing). Photos: Lars Iversen.",
"metadata": {}
},
{
"id": 786,
"image": "PMC2779145_f2_51187.jpg",
"report": "Rat lenses in various groups. A and B are normal lenses, C and D are selenite induced lenses, and E and F are selenite + Drevogenin D induced lenses. The magnifications of A, C, and E were 40X and the magnification of B, D, and F was 200X.",
"metadata": {}
},
{
"id": 787,
"image": "PMC2374454_F2_22008.jpg",
"report": "Macroscopic observation. Femoral and tibial articular cartilage stained with India ink. Cartilage lesions are indicated by arrowheads. Lat, lateral; Med, medial.",
"metadata": {}
},
{
"id": 788,
"image": "PMC2804726_F2_54626.jpg",
"report": "(A) Haematoxylin and eosin (H&E) staining (× 10) of nasal biopsy showing mucosal ulceration (B) H&E (× 40) showing extensive inflammatory reaction in the corium, with hyperplastic rete processes, and giant cells.",
"metadata": {}
},
{
"id": 789,
"image": "PMC2889896_F1_66891.jpg",
"report": "Immmunohistochemical staining of sections of xenografts. Immmunohistochemical staining after ex vivo application of cetuximab to identify ErbB1 expression (upper panels) or of trastuzumab to identify ErbB2 expression (lower panels). Scale bar = 100 μm.",
"metadata": {}
},
{
"id": 790,
"image": "PMC3044656_F2_88067.jpg",
"report": "[3H]-PK11195 (a,b) and [3H]-paroxetine (c,d) autoradiography in coronal hypothalamic-hippocampal sections of WT and ob/ob brain. The increased signal corresponding to [3H]-PK11195 binding in sections of ob/ob mice is indicated by arrows (hippocampal region and choroids plexus-third ventricle). cc: cerebral cortex; hi: hippocampal region; hy: hypothalamus; th: thalamus.",
"metadata": {}
},
{
"id": 791,
"image": "PMC2364795_fig5_21757.jpg",
"report": "Immunohistochemical detection of WWOX protein in normal liver and HCC. Representative immunostaining results of WWOX protein expression. (A) Normal liver tissue sample. Note the strong WWOX cytoplasmic staining of hepatocytes contrasting with the negative staining of the stromal components (lower left corner). (B) HCC tissue sample demonstrating very weak WWOX staining. (C) HCC sample negative for WWOX staining.",
"metadata": {}
},
{
"id": 792,
"image": "PMC1892559_F4_11667.jpg",
"report": "Immunolocalization of Hic-5 protein in the longitudinal smooth muscle layer of rat myometrium at d15, d17, d19, d21, d22, d23 of gestation and post-partum (PP). On d15 Hic-5 was detectable as distinct, well separated punctate foci at plasma membranes (arrowheads) while at subsequent timepoints, and particularly in PP samples, Hic-5 became consistently detected as an almost continuous line of intense fluorescence at cell membranes (arrows). Control = mouse IgG. Scale bar = 50 μm.",
"metadata": {}
},
{
"id": 793,
"image": "PMC2938245_fig1_73387.jpg",
"report": "Immunostaining of EGFR and mTOR pathways in SCLC. Immunohistochemical staining of SCLC for (A) p-mTOR, (B) p-p70s6K (strongly stained mitoses are marked by arrows), (C) p-AKT, (D) p-ERK and (E) EGFR (all magnification × 400).",
"metadata": {}
},
{
"id": 794,
"image": "PMC2629709_f6_33040.jpg",
"report": "Thy1.1 and BDNF immunocytochemistry in differentiated RGC-5 cells. Thy1.1 (A) and BDNF (C) immunoreactivity are present in differentiated RGC-5 cells. Higher magnification showed that Thy1.1 (B) and BDNF (D)-positive RGC-5 cells extend neurites (arrowheads). Size bar represents 20 µm (B and D).",
"metadata": {}
},
{
"id": 795,
"image": "PMC2933633_F3_72755.jpg",
"report": "Biopsy of colonic mucosa adjacent to the ulcer; immunohistochemistry with anti-CD3, -CD4, and -CD8. The colic mucosa is regenerative, with less mucus in the cytoplasm of the epithelial cells. The lamina propria contains some neutrophils, which infiltrate the epithelial cells (arrow), without an increase of mononuclear cells. In this inflamed mucosa, fewer CD4+ cells (arrow) than CD8+ T cells (arrow) are found.",
"metadata": {}
},
{
"id": 796,
"image": "PMC2765826_ppat-1000642-g003_48428.jpg",
"report": "Gross pathology of the lung post-mortem in ferrets treated with m102.4 prior to NiV challenge.(A) Ferret 21-pre; 20 days post infection (dpi): no signs of illness, disease or lesions: healthy ferret lungs. (B) Ferret 23-pre; 13 dpi: delayed disease onset, scattered small pinpoint lesions. (C) Ferret 24-pre; 13 dpi: delayed disease onset, scattered small pinpoint lesions. (D) NiV-infected control ferret; 8 dpi: typical disease onset, extensive pinpoint lesions.",
"metadata": {}
},
{
"id": 797,
"image": "PMC2738668_F1_44929.jpg",
"report": "Light-microscopy of a representative Glomerulum and the tubulus-interstitium (A, B) and ultrastructure of a glomerulum with missing podocytes and thin basements without deposits (C, D).",
"metadata": {}
},
{
"id": 798,
"image": "PMC2928297_pone-0012398-g002_72194.jpg",
"report": "Cytoplasmic or chromosome arm targeting results in normal cytokinetic progression.Non-tip ablations and progression through cell division: A. Cytoplasmic targeting distal from the midzone (box). B. Chromosome arm ablation (arrow). C. Cytoplasmic midzone targeting (box). Time stamps indicated in each figure take 00:00:00 as immediately pre ablation and are formatted as hh:mm:ss. Scale bar represents 5 µm.",
"metadata": {}
},
{
"id": 799,
"image": "PMC2915925_pone-0011953-g002_70643.jpg",
"report": "Identification of peroxisomal mutants.Bright field images are shown on the left panel and fluorescence images are shown on the right. Known peroxins show mislocalization of the Pot1p-GFP reporter when deleted. Partial mislocalization phenotypes are seen in pex1Δ, pex18Δ, and pex21Δ.",
"metadata": {}
}
]
================================================
FILE: data/test/report/quilt-1m_test.json
================================================
[
{
"": "1006600",
"caption": "The cytoplasmic features of smaller and larger benign glands are similar, which is important to note before looking at stains.",
"image_path": "iklRyY1nBIE_image_3c9e460f-53aa-4de5-b34f-c3d6316750be.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " for a second, because when I show you the stains, it's going to be important for you to correlate what you're seeing now with the stains. So one other thing I want to draw your attention to before we look at the pink cocktail is that the cytoplasmic features of these smaller glands and even the larger benign glands next door are somewhat similar. So that's going to become very important when I show you these things. So we'll go ahead and look at the corresponding pink cocktail on that case. And this",
"corrected_text": " for a second, because when I show you the stains, it's going to be important for you to correlate what you're seeing now with the stains. So one other thing I want to draw your attention to before we look at the pink cocktail is that the cytoplasmic features of these smaller glands and even the larger benign glands next door are somewhat similar. So that's going to become very important when I show you these things. So we'll go ahead and look at the corresponding pink cocktail on that case. And this",
"med_umls_ids": "[[{'entity': 'cytoplasmic', 'concept_id': 'C0010834', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'smaller', 'concept_id': 'C0547044', 'confidence': 0.9999998807907104}, {'entity': 'benign glands', 'concept_id': 'C1301287', 'confidence': 0.726940393447876}, {'entity': 'stains', 'concept_id': 'C0038128', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_0",
"caption_rating": "8"
},
{
"": "1006971",
"caption": "Whirling pattern can be seen in perineurioma and dermatofibrosarcoma protuberans (DFSP).",
"image_path": "QDb68_G1HR4_image_5034c21b-cf71-4dc4-a11f-7800619e493a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['whirling pattern']",
"noisy_text": " This one's not really showing that but some of them do, they have a lot of whirling pattern. So the two other things that keep in the differential here are perineurioma and also dermatofibrosarcoma protuberans, DFSP, which also has a tends to have a story form or whirled and swirled growth pattern and also has a translocation sarcoma, has very bland spindle cells. Okay, I guess I don't have any immunostains with me to show you today but just briefly the immunostains, most of the immunostains that we use for soft tissue tumors are negative most of the time in low-grade fibromyxoid sarcoma. CD34 is usually negative which is a pretty easy way to separate this from DFSP. The other thing is that low-grade fibromyxoid sarcoma usually is a relatively larger and deep, deep soft tissue below the fascia mass, although there are rare examples that are small and superficial and those seem to be more common in children. But DFSP is essentially always in the skin, the dermis or subcutaneous and rarely ever involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is",
"corrected_text": " This one's not really showing that but some of them do, they have a lot of whirling pattern. So the two other things that keep in the differential here are perineurioma and also dermatofibrosarcoma protuberans, DFSP, which also has a tends to have a story form or whirled and swirled growth pattern and also has a translocation sarcoma, has very bland spindle cells. Okay, I guess I don't have any immunostaining with me to show you today but just briefly the immunostaining, most of the immunostaining that we use for soft tissue tumors are negative most of the time in low-grade fibromyxoid sarcoma. CD34 is usually negative which is a pretty easy way to separate this from DFSP. The other thing is that low-grade fibromyxoid sarcoma usually is a relatively larger and deep, deep soft tissue below the fascia mass, although there are rare examples that are small and superficial and those seem to be more common in children. But DFSP is essentially always in the skin, the dermis or subcutaneous and rarely ever involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is",
"med_umls_ids": "[[{'entity': 'Whirling pattern', 'concept_id': 'C0449774', 'confidence': 0.6110570430755615}, {'entity': 'perineurioma', 'concept_id': 'C0751691', 'confidence': 0.9999999403953552}, {'entity': 'dermatofibrosarcoma protuberans', 'concept_id': 'C0206647', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}], [{'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}, {'entity': 'skin', 'concept_id': 'C0444099', 'confidence': 1.0}, {'entity': 'deep soft tissue', 'concept_id': 'C0225317', 'confidence': 0.7996832728385925}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_1",
"caption_rating": "8"
},
{
"": "1007238",
"caption": "Bladder neck invasion is present.",
"image_path": "iklRyY1nBIE_image_85611e49-f237-49c9-b10b-8feb8ef5f243.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['bladder neck', 'prostate', 'biopsy']",
"noisy_text": " And it actually invaded into the bladder. So there was bladder-neck invasion. That was very, very important to document in the report. It's not just good enough to say small cell carcinoma adjacent high-grade prostate cancer. You need to also document the fact that it invades the bladder-neck. That's very, very important for completeness. So on this one, I have just a little biopsy here to show you. So this is a prostate-needle-cored biopsy. That's what this was called, prostate-needle-cored biopsy. And as",
"corrected_text": " And it actually invaded into the bladder. So there was bladder-neck invasion. That was very, very important to document in the report. It's not just good enough to say small cell carcinoma adjacent high-grade prostate cancer. You need to also document the fact that it invades the bladder-neck. That's very, very important for completeness. So on this one, I have just a little biopsy here to show you. So this is a prostate needle biopsy-cored biopsy. That's what this was called, prostate needle biopsy-cored biopsy. And as",
"med_umls_ids": "[[{'entity': 'Small cell carcinoma', 'concept_id': 'C0149925', 'confidence': 1.0}, {'entity': 'adjacent', 'concept_id': 'C0205117', 'confidence': 1.0}, {'entity': 'high-grade', 'concept_id': 'C1512433', 'confidence': 0.9347730875015259}], [{'entity': 'Bladder', 'concept_id': 'C0005682', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_2",
"caption_rating": "8"
},
{
"": "1005109",
"caption": "The criteria for dysplasia include loss of cellular polarity and nuclei reaching the surface.",
"image_path": "r7OA0Trj5hQ_image_2d6015c3-0d6c-43bc-80f4-d0bfce1b929d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Nuclei reaching the surface', 'Cribriform and micropapillary patterns', 'Nuclei reaching the surface', 'Cribriform and micropapillary patterns', 'Nuclei reaching the surface', 'Cribriform and micropapillary patterns']",
"noisy_text": " And the criteria are loss of polarity, nuclei reaching the surface. Here you can see nuclei reaching the surface. Prominent nuclei, if you see carefully for 10 seconds, you can start seeing the nuclei and cribriformic and micropapillary. This concept of dysplasia, low-grade dysplasia and high-grade dysplasia is very, very essential because you can apply this criteria in any organ. You can apply it in the pancreas. You can apply it in the gallbladder. You can apply it in the bile duct. Even you can apply it in the breast. You can apply it in the prostate. You can apply it",
"corrected_text": " And the criteria are loss of polarity, nuclei reaching the surface. Here you can see nuclei reaching the surface. Prominent nuclei, if you see carefully for 10 seconds, you can start seeing the nuclei and cribriform and micropapillary. This concept of dysplasia, low-grade dysplasia and high-grade dysplasia is very, very essential because you can apply this criteria in any organ. You can apply it in the pancreas. You can apply it in the gallbladder. You can apply it in the bile duct. Even you can apply it in the breast. You can apply it in the prostate. You can apply it",
"med_umls_ids": "[[{'entity': 'criteria', 'concept_id': 'C0243161', 'confidence': 0.9999998807907104}, {'entity': 'dysplasia', 'concept_id': 'C0334044', 'confidence': 1.0}, {'entity': 'loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'cellular polarity', 'concept_id': 'C0085304', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}], [{'entity': 'Prominent', 'concept_id': 'C0205402', 'confidence': 0.9999999403953552}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'cribriform', 'concept_id': 'C1621425', 'confidence': 0.9999999403953552}, {'entity': 'micropapillary', 'concept_id': 'C1290608', 'confidence': 0.891559898853302}, {'entity': 'patterns', 'concept_id': 'C0449774', 'confidence': 1.0}, {'entity': 'indicative', 'concept_id': 'C2985705', 'confidence': 0.7675144076347351}, {'entity': 'dysplasia', 'concept_id': 'C0334044', 'confidence': 1.0}], [{'entity': 'concept', 'concept_id': 'C0178566', 'confidence': 1.0}, {'entity': 'dysplasia', 'concept_id': 'C0334044', 'confidence': 1.0}, {'entity': 'essential', 'concept_id': 'C0205224', 'confidence': 0.9999999403953552}, {'entity': 'organs', 'concept_id': 'C0178784', 'confidence': 1.0}, {'entity': 'pancreas', 'concept_id': 'C0030274', 'confidence': 0.9999999403953552}, {'entity': 'gallbladder', 'concept_id': 'C0016976', 'confidence': 0.9999999403953552}, {'entity': 'bile duct', 'concept_id': 'C0005400', 'confidence': 1.0}, {'entity': 'breast', 'concept_id': 'C0006141', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_3",
"caption_rating": "8"
},
{
"": "1004466",
"caption": "Unique collagen pattern seen in a particular tumor, possibly related to hyalinization in collagen seen around smaller vessels.",
"image_path": "QDb68_G1HR4_image_fd8abd92-28c1-4588-b9b8-f76050c101f8.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " flipped here you can see this unique collagen pattern in this particular tumor. And I don't know but I kind of suspect that these collagen rosettes may be related to the hyalinization in collagen that we see around smaller vessels like I showed in that tumor the example earlier that this may just be a more dramatic example. Now one other tumor that might enter the differential here is the so-called neuroblastoma-like variant of schwannoma or neurilomoma neuroblastoma-like schwannoma. It has also big collagen rich rosettes like this but it has a much more prominent round cell appearance around the edge of the rim of the nodules are very like small round blue cell almost",
"corrected_text": " flipped here you can see this unique collagen pattern in this particular tumor. And I don't know but I kind of suspect that these collagen rosettes may be related to the hyalinization in collagen that we see around smaller vessels like I showed in that tumor the example earlier that this may just be a more dramatic example. Now one other tumor that might enter the differential here is the so-called neuroblastoma-like variant of schwannoma or neurilomoma neuroblastoma-like schwannoma. It has also big collagen rich rosettes like this but it has a much more prominent round cell appearance around the edge of the rim of the nodules are very like small round blue cell almost",
"med_umls_ids": "[[{'entity': 'Unique', 'concept_id': 'C1710548', 'confidence': 1.0}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'hyalinization', 'concept_id': 'C0333438', 'confidence': 1.0}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'vessels', 'concept_id': 'C0005847', 'confidence': 1.0}], [{'entity': 'Neuroblastoma-like variant', 'concept_id': 'C1419295', 'confidence': 0.6672105193138123}, {'entity': 'schwannoma', 'concept_id': 'C0027809', 'confidence': 0.9999998807907104}, {'entity': 'differential', 'concept_id': 'C0443199', 'confidence': 1.0}, {'entity': 'round cell', 'concept_id': 'C0487470', 'confidence': 1.0}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'edge', 'concept_id': 'C0205154', 'confidence': 1.0}, {'entity': 'nodules', 'concept_id': 'C0028259', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_4",
"caption_rating": "7"
},
{
"": "1005341",
"caption": "Clinical description of a skin condition with small individual papules that have a central crust, often on perioral skin.",
"image_path": "udoW6VSqsm4_image_24d23039-b3f2-46db-8ca2-24721d0b7540.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['small individual papules', 'central crust', 'perioral skin', 'granulomatous condition', 'palisade granulostermatitis', 'neutrophilic dermatosis', 'older individuals', 'perineoplastic process']",
"noisy_text": " Yeah, this would be more kind of the classic one, probably. What else? Here's the classic one clinically. What if there's small individual papules that have a central crust in them, often on apral skin? We have had several cases of the disseminated GA, but I'm not sure if they didn't have a crust. So, what's the type that had it? Perforating? Perforating GA. Perforating GA, good. So, this was granulomanuary. There's one other condition that gives you palisade granulostermatitis like this, but it also gives you some neutrophils infiltrate. That palisade and neutrophilic granulostermatitis, that's another thing that you at least have to think about when you see GA. If you see an older person that's got disseminated GA, think about it as a perineoplastic process. Sometimes you",
"corrected_text": " Yeah, this would be more kind of the classic one, probably. What else? Here's the classic one clinically. What if there's small individual papules that have a central crust in them, often on perioral skin? We have had several cases of the disseminated GA, but I'm not sure if they didn't have a crust. So, what's the type that had it? Perforating? Perforating GA. Perforating GA, good. So, this was granulomatous. There's one other condition that gives you palisade granulostermatitis like this, but it also gives you some neutrophils infiltrate. That palisade and neutrophilic dermatosis, that's another thing that you at least have to think about when you see GA. If you see an older person that's got disseminated GA, think about it as a perineoplastic process. Sometimes you",
"med_umls_ids": "[[{'entity': 'Clinical', 'concept_id': 'C0205210', 'confidence': 1.0}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'skin condition', 'concept_id': 'C1719933', 'confidence': 1.0}, {'entity': 'individual', 'concept_id': 'C0027361', 'confidence': 1.0}, {'entity': 'papules', 'concept_id': 'C0332563', 'confidence': 0.9999999403953552}, {'entity': 'central crust', 'concept_id': 'C0205204', 'confidence': 0.7633819580078125}, {'entity': 'perioral skin', 'concept_id': 'C0448802', 'confidence': 0.8075158596038818}], [{'entity': 'Perforating', 'concept_id': 'C0549099', 'confidence': 1.0}, {'entity': 'GA', 'concept_id': 'C0002915', 'confidence': 1.0}, {'entity': 'granulomatous condition', 'concept_id': 'C0439667', 'confidence': 0.8219265341758728}, {'entity': 'palisade', 'concept_id': 'C0331512', 'confidence': 0.8241410255432129}, {'entity': 'granulostermatitis', 'concept_id': 'C0743086', 'confidence': 0.7311265468597412}], [{'entity': 'Neutrophilic dermatosis', 'concept_id': 'C1142272', 'confidence': 1.0}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'GA', 'concept_id': 'C0002915', 'confidence': 1.0}], [{'entity': 'Disseminated', 'concept_id': 'C0205221', 'confidence': 1.0}, {'entity': 'GA', 'concept_id': 'C0002915', 'confidence': 1.0}, {'entity': 'older', 'concept_id': 'C0337524', 'confidence': 0.7771234512329102}, {'entity': 'individuals', 'concept_id': 'C0027361', 'confidence': 0.8766164779663086}, {'entity': 'perineoplastic process', 'concept_id': 'C0027671', 'confidence': 0.8771522045135498}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_5",
"caption_rating": "8"
},
{
"": "1007649",
"caption": "Membranous lipodystrophy seen at the periphery of the fat microcysts.",
"image_path": "hoV-JkD6Wb0_image_ae24eba8-c8b9-412b-9009-f7ba4d5b0c4a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['Large fat microcysts', 'Membranous lipodystrophy at the periphery of the fat microcysts', 'Arabesque-type fibular material at the periphery of the fat microcysts', 'Remnant cell walls of adipocytes at the periphery of the fat microcysts', 'Large fat microcysts', 'Membranous lipodystrophy at the periphery of the fat microcysts', 'Arabesque-type fibular material at the periphery of the fat microcysts', 'Remnant cell walls of adipocytes at the periphery of the fat microcysts']",
"noisy_text": " inflammation. There aren't many viable adipocytes left here. A lot of the adipocytes have kind of ruptured and fused, and so we've got these large fat microcysts, and if we look at the periphery of the fat microcyst, we've got this lipomembranous change, this kind of arabesque-type fibular material out at the periphery, which basically represents coalescence of remnant cell walls of adipocytes. In addition, within the surrounding tissue, there's a little bit of fibrosis. There are a few lipophages and a very sparse infiltrative",
"corrected_text": " inflammation. There aren't many viable adipocytes left here. A lot of the adipocytes have kind of ruptured and fused, and so we've got these large fat microcysts, and if we look at the periphery of the fat microcyst, we've got this lipomembranous change, this kind of arabesque-type fibular material out at the periphery, which basically represents coalescence of remnant cell walls of adipocytes. In addition, within the surrounding tissue, there's a little bit of fibrosis. There are a few lipophages and a very sparse infiltrative",
"med_umls_ids": "[[{'entity': 'Inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}], [{'entity': 'adipocytes', 'concept_id': 'C0206131', 'confidence': 1.0}, {'entity': 'left', 'concept_id': 'C0205091', 'confidence': 1.0}], [{'entity': 'fat microcysts', 'concept_id': 'C1513269', 'confidence': 0.871767520904541}], [{'entity': 'Membranous lipodystrophy', 'concept_id': 'C0406599', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'fat microcysts', 'concept_id': 'C1513269', 'confidence': 0.871767520904541}], [{'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'fat microcysts', 'concept_id': 'C1513269', 'confidence': 0.871767520904541}], [{'entity': 'Coalescence', 'concept_id': 'C4727092', 'confidence': 0.8749340176582336}, {'entity': 'remnant', 'concept_id': 'C3272697', 'confidence': 1.0}, {'entity': 'cell walls', 'concept_id': 'C0007623', 'confidence': 1.0}, {'entity': 'adipocytes', 'concept_id': 'C0206131', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'fat microcysts', 'concept_id': 'C1513269', 'confidence': 0.871767520904541}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_6",
"caption_rating": "8"
},
{
"": "1007549",
"caption": "Dome-shaped papule with nests of melanocytes along the DEJ.",
"image_path": "8S4LeiO6Bbk_image_d36fb884-e375-4e73-b4ad-f1028870d68d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['dome-shaped papule']",
"noisy_text": " because this was the initial shave. And you can see that we've got a dome-shaped papule here. And we've got a few nests of melanocytes along the DEJ. And these melanocytes are normal in appearance, a round oval nuclei and a moderate amount of cytoplasm. And then we have nest cords and strands of otherwise banal appearing or banal appearing melanocytes present within the underlying dermis. There is evidence of maturation with depth in these sections, and no mitotic pairs. In the central portion of the specimen, you can see that the dermis is a little more sclerotic. And we've got the presence of separately heavily pigmented melanovagias. And then if we",
"corrected_text": " because this was the initial shave. And you can see that we've got a dome-shaped papule here. And we've got a few nests of melanocytes along the DEJ. And these melanocytes are normal in appearance, a round oval nuclei and a moderate amount of cytoplasm. And then we have nest cords and strands of otherwise banal appearing or banal appearing melanocytes present within the underlying dermis. There is evidence of maturation with depth in these sections, and no mitotic pairs. In the central portion of the specimen, you can see that the dermis is a little more sclerotic. And we've got the presence of separately heavily pigmented melanovagias. And then if we",
"med_umls_ids": "[[{'entity': 'Dome-shaped papule', 'concept_id': 'C1711316', 'confidence': 0.752353847026825}, {'entity': 'nests', 'concept_id': 'C0035253', 'confidence': 0.7275967001914978}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'DEJ', 'concept_id': 'C0385794', 'confidence': 0.5962325930595398}], [{'entity': 'Nest cords', 'concept_id': 'C0884973', 'confidence': 0.7039703726768494}, {'entity': 'strands', 'concept_id': 'C0600383', 'confidence': 0.800572395324707}, {'entity': 'banal', 'concept_id': 'C0004722', 'confidence': 0.7279530763626099}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}], [{'entity': 'Evidence', 'concept_id': 'C3887511', 'confidence': 1.0}, {'entity': 'maturation', 'concept_id': 'C0678723', 'confidence': 1.0}, {'entity': 'depth', 'concept_id': 'C0205125', 'confidence': 1.0}, {'entity': 'mitotic', 'concept_id': 'C1513354', 'confidence': 1.0}, {'entity': 'pairs', 'concept_id': 'C0600436', 'confidence': 0.8094210028648376}], [{'entity': 'Sclerotic', 'concept_id': 'C0036429', 'confidence': 0.9999999403953552}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'melanophages', 'concept_id': 'C3280463', 'confidence': 0.9375340938568115}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_7",
"caption_rating": "8"
},
{
"": "1004641",
"caption": "Neuroendocrine cell aggregates and apoptotic bodies are not seen in mycophenol-associated injury.",
"image_path": "sDFjOtMAYrk_image_4505e5f8-8d5f-4ace-9e27-e50990dd4a27.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "[]",
"noisy_text": " with microphenol-associated injury have many more in the way of eosinophils, a lot more in the way of eosinophils than GVHD patients do. So that's really, really helpful. Is there a number? I think it's more than 15 per high power field. Typically, I just say, you know, the presence of eosinophils or prominent eosinophils favors microphenol. The other thing is you don't see any neuroendocrine cell aggregates. Those you see in GVHD. The other thing is you don't see apoptotic micro abscesses. Those will be in GVHD and you will not see them in microphenol. And then, you know, actually, the main finding, let's talk about the main finding, which is what? Yeah, exactly.",
"corrected_text": " with microphenol-associated injury have many more in the way of eosinophils, a lot more in the way of eosinophils than GVHD patients do. So that's really, really helpful. Is there a number? I think it's more than 15 per high power field. Typically, I just say, you know, the presence of eosinophils or prominent eosinophils favors microphenol. The other thing is you don't see any neuroendocrine cell aggregates. Those you see in GVHD. The other thing is you don't see apoptotic micro abscesses. Those will be in GVHD and you will not see them in microphenol. And then, you know, actually, the main finding, let's talk about the main finding, which is what? Yeah, exactly.",
"med_umls_ids": "[[{'entity': 'Mycophenol-associated injury', 'concept_id': 'C0552509', 'confidence': 0.6023857593536377}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'GVHD', 'concept_id': 'C0018133', 'confidence': 1.0}, {'entity': 'patients', 'concept_id': 'C0030705', 'confidence': 1.0}], [{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'mycophenol', 'concept_id': 'C0883242', 'confidence': 0.8315404653549194}], [{'entity': 'Neuroendocrine cell', 'concept_id': 'C1518275', 'confidence': 1.0}, {'entity': 'aggregates', 'concept_id': 'C0205418', 'confidence': 1.0}, {'entity': 'apoptotic bodies', 'concept_id': 'C3269134', 'confidence': 1.0}, {'entity': 'mycophenol-associated injury', 'concept_id': 'C0552509', 'confidence': 0.6023857593536377}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_8",
"caption_rating": "9"
},
{
"": "1007248",
"caption": "Glut-1 is usually negative in perineuriomas, but there are rare reports of positive staining in low-grade fibromyxoid sarcomas.",
"image_path": "QDb68_G1HR4_image_7807ddd7-4e7e-4a1d-aeba-2e2b021c55bc.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Deep soft tissue', 'Perineurioma', 'Low-grade fibromyxoid sarcoma', 'Immunohistochemistry', 'Swirling growth']",
"noisy_text": " involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is more of a difficult problem because perineurioma has a lot of overlap histologically with low-grade fibromyxoid sarcoma and also immunohistochemically. On immunostains, EMA, Clodin-1 and Glut-1 are three immunostains that will usually stain perineuriomas. The problem is that low-grade fibromyxoid sarcomas often express at least focal EMA, so that's a problem and additionally, the examples of low-grade fibromyxoid sarcoma that have dramatic swirling and whirling growth, those are the ones that have a perineurioma like pattern, the ones that mimic perineurioma. They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The",
"corrected_text": " involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is more of a difficult problem because perineurioma has a lot of overlap histologically with low-grade fibromyxoid sarcoma and also immunohistochemically. On immunostains, EMA, Clodin-1 and Glut-1 are three immunostains that will usually stain perineuriomas. The problem is that low-grade fibromyxoid sarcomas often express at least focal EMA, so that's a problem and additionally, the examples of low-grade fibromyxoid sarcoma that have dramatic swirling and whirling growth, those are the ones that have a perineurioma like pattern, the ones that mimic perineurioma. They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The",
"med_umls_ids": "[[{'entity': 'CD34', 'concept_id': 'C0054953', 'confidence': 1.0}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'deep soft tissue tumors', 'concept_id': 'C0037579', 'confidence': 0.8622524738311768}], [{'entity': 'Perineurioma', 'concept_id': 'C0751691', 'confidence': 0.9999999403953552}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'histologically', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'immunohistochemistry', 'concept_id': 'C0021044', 'confidence': 0.9999998807907104}], [{'entity': 'EMA', 'concept_id': 'C0268596', 'confidence': 0.9999999403953552}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}, {'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'immunohistochemical stains', 'concept_id': 'C4317108', 'confidence': 0.9999999403953552}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibrosarcomas', 'concept_id': 'C0016057', 'confidence': 1.0}, {'entity': 'EMA', 'concept_id': 'C0268596', 'confidence': 0.9999999403953552}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}], [{'entity': 'Low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'swirling', 'concept_id': 'C0233591', 'confidence': 0.7064549922943115}, {'entity': 'growth', 'concept_id': 'C0018270', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'express', 'concept_id': 'C0017262', 'confidence': 0.8176293969154358}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}], [{'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'reports', 'concept_id': 'C0684224', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcomas', 'concept_id': 'C1275282', 'confidence': 0.8123146891593933}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_9",
"caption_rating": "8"
},
{
"": "1007889",
"caption": "Subepidermal blistering disease with eosinophils is a possibility.",
"image_path": "udoW6VSqsm4_image_012ac31a-54ca-4990-b628-3e36ec5ff0ff.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['inflammation', 'eosinophils', 'subepidermal blistering disease', 'inflammation', 'eosinophils', 'subepidermal blistering disease']",
"noisy_text": " There's a heck of a lot of inflammation there. I guess it has to be super inflamed for the Irish. They play rugby over there. Irish soccer, I learned that. I didn't know what Irish soccer was. They're a combination of rugby and soccer. They have no pads. They're smashing each other, so I guess they have to be tough to be Irish. They have a lot of inflammation. This is pretty inflamed. Yeah. A lot of eosinophils too, right? Yes, eos. Yeah, for sure. What do we think of with subepidermal blistering disease with eosinophils? I was more drawn to the eosinophils. I thought there was some germophilic protecting. There's a little bit of that. I thought",
"corrected_text": " There's a heck of a lot of inflammation there. I guess it has to be super inflamed for the Irish. They play rugby over there. Irish soccer, I learned that. I didn't know what Irish soccer was. They're a combination of rugby and soccer. They have no pads. They're smashing each other, so I guess they have to be tough to be Irish. They have a lot of inflammation. This is pretty inflamed. Yeah. A lot of eosinophils too, right? Yes, eos. Yeah, for sure. What do we think of with subepidermal blistering disease with eosinophils? I was more drawn to the eosinophils. I thought there was some germophilic protecting. There's a little bit of that. I thought",
"med_umls_ids": "[[{'entity': 'inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}, {'entity': 'physical activity', 'concept_id': 'C0015259', 'confidence': 1.0}, {'entity': 'rugby', 'concept_id': 'C0035945', 'confidence': 1.0}, {'entity': 'Irish', 'concept_id': 'C0087186', 'confidence': 0.9999999403953552}, {'entity': 'soccer', 'concept_id': 'C0037393', 'confidence': 1.0}], [{'entity': 'Subepidermal blistering disease', 'concept_id': 'C3670030', 'confidence': 0.9999999403953552}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}], [{'entity': 'Eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_10",
"caption_rating": "8"
},
{
"": "1004376",
"caption": "Nodules around joints can be seen in gout, RA, and OE.",
"image_path": "udoW6VSqsm4_image_4616f6ad-a0aa-43a0-a0ed-7b746818cd8e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " You notice this is on acral skin. There are often nodules in that area, and they can start off as palpable purpura in some cases. So, it's like, you know, regular leukocytoplastic vasculitis that can end up with these nodular lesions. Next slide. What is the histologic identical twin of this process? The granulomyphial. Yes, excellent. Granulomyphial looks very, very similar to this on the microscope. Obviously, clinically, it's not like this. It's on the face. It's on the pseudolymphoma. Next slide. So, this is a type of chronic vasculitis that ends up forming these fibrotic nodules. It's an interesting condition, and it is thought to be associated with other conditions. So, you want to make sure that you don't just, next case. A lot of times, these things can give you cholesterol clefts. One of the old names for this years ago used to be extracellular cholesterolosis, and it would give you these, all these neutrophils would gradually degranulate, if you will. The neutrophil products would have lipid in them, and you'd get these cholesterol clefts that would look kind of yellowish. Now, what are a couple other clinical diseases where you can see nodules around joints? You know, like, gout, RA, OE. Good. Gout, RA. There's",
"corrected_text": " You notice this is on acral skin. There are often nodules in that area, and they can start off as palpable purpura in some cases. So, it's like, you know, leukocytoclastic vasculitis that can end up with these nodular lesions. Next slide. What is the histologic identical twin of this process? The granuloma faciale. Yes, excellent. granuloma faciale looks very, very similar to this on the microscope. Obviously, clinically, it's not like this. It's on the face. It's on the pseudolymphoma. Next slide. So, this is a type of chronic vasculitis that ends up forming these fibrotic nodules. It's an interesting condition, and it is thought to be associated with other conditions. So, you want to make sure that you don't just, next case. A lot of times, these things can give you cholesterol clefts. One of the old names for this years ago used to be extracellular cholesterolosis, and it would give you these, all these neutrophils would gradually degranulate, if you will. The neutrophil products would have lipid in them, and you'd get these cholesterol clefts that would look kind of yellowish. Now, what are a couple other clinical diseases where you can see nodules around joints? You know, like, gout, RA, OE. Good. Gout, RA. There's",
"med_umls_ids": "[[{'entity': 'Nodules', 'concept_id': 'C0028259', 'confidence': 1.0}, {'entity': 'acral skin', 'concept_id': 'C0444099', 'confidence': 0.7122198939323425}, {'entity': 'leukocytoclastic vasculitis', 'concept_id': 'C0151436', 'confidence': 1.0}, {'entity': 'nodular', 'concept_id': 'C0205297', 'confidence': 1.0}, {'entity': 'lesions', 'concept_id': 'C0221198', 'confidence': 1.0}], [{'entity': 'Granuloma faciale', 'concept_id': 'C0239495', 'confidence': 1.0}, {'entity': 'histologic', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'identical', 'concept_id': 'C0205280', 'confidence': 1.0}, {'entity': 'twin', 'concept_id': 'C0041427', 'confidence': 0.9999999403953552}, {'entity': 'process', 'concept_id': 'C1184743', 'confidence': 1.0}], [{'entity': 'Granuloma faciale', 'concept_id': 'C0239495', 'confidence': 1.0}, {'entity': 'leukocytoclastic vasculitis', 'concept_id': 'C0151436', 'confidence': 1.0}, {'entity': 'microscope', 'concept_id': 'C0181839', 'confidence': 1.0}], [{'entity': 'Chronic vasculitis', 'concept_id': 'C0042384', 'confidence': 0.7992802858352661}, {'entity': 'fibrotic nodules', 'concept_id': 'C0332561', 'confidence': 0.8351579308509827}], [{'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'associated with', 'concept_id': 'C0332281', 'confidence': 1.0}, {'entity': 'conditions', 'concept_id': 'C0012634', 'confidence': 0.8556983470916748}], [{'entity': 'Extracellular cholesterolosis', 'concept_id': 'C2973528', 'confidence': 0.9169934391975403}, {'entity': 'cholesterol clefts', 'concept_id': 'C3686582', 'confidence': 0.9999999403953552}, {'entity': 'yellowish nodules', 'concept_id': 'C1867455', 'confidence': 0.8135299682617188}], [{'entity': 'Nodules', 'concept_id': 'C0028259', 'confidence': 1.0}, {'entity': 'joints', 'concept_id': 'C0022417', 'confidence': 1.0}, {'entity': 'gout', 'concept_id': 'C0018099', 'confidence': 1.0}, {'entity': 'RA', 'concept_id': 'C0002893', 'confidence': 1.0}, {'entity': 'OE', 'concept_id': 'C1551089', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_11",
"caption_rating": "7"
},
{
"": "1004413",
"caption": "Ganglion cells in the submucosa are a normal component and may be mistaken for malignancy.",
"image_path": "r7OA0Trj5hQ_image_391ca795-2aab-4b66-9f24-6486937d85d6.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['neural hypertrophy', 'ganglion cells', 'submucosa', 'congenital megacolon', 'submucosa']",
"noisy_text": " for example, carotid endoartrectomy or abdominal aortic encephalopathy, that history is very important for cholesterol emboli. Here, there is more like a neural hypertrophy. Whenever you see neural hypertrophy, you have to think of Crohn's disease. Here, you see the ganglion cells in the submicosa. When you see ganglion cells, these are normal component of the submicosa. And why I am showing it, sometimes you may think of malignancy. Here, you may not think of it. And another point, these are all the cells we are looking in congenital mecagola. So if you don't see them in the submicosa in frozen section, again, this will qualify for congenital mecagola. Here, another tricky thing. This is",
"corrected_text": " for example, carotid endarterectomy or abdominal aortic encephalopathy, that history is very important for cholesterol emboli. Here, there is more like a neural hypertrophy. Whenever you see neural hypertrophy, you have to think of Crohn's disease. Here, you see the ganglion cells in the submucosa. When you see ganglion cells, these are normal component of the submucosa. And why I am showing it, sometimes you may think of malignancy. Here, you may not think of it. And another point, these are all the cells we are looking in congenital megacolon. So if you don't see them in the submucosa in frozen section, again, this will qualify for congenital megacolon. Here, another tricky thing. This is",
"med_umls_ids": "[[{'entity': 'History', 'concept_id': 'C0019664', 'confidence': 1.0}, {'entity': 'carotid endarterectomy', 'concept_id': 'C0014099', 'confidence': 1.0}, {'entity': 'abdominal aortic encephalopathy', 'concept_id': 'C0507867', 'confidence': 0.6308470964431763}, {'entity': 'cholesterol emboli', 'concept_id': 'C0149649', 'confidence': 0.8653062582015991}], [{'entity': 'Neural hypertrophy', 'concept_id': 'C0020564', 'confidence': 0.8345715999603271}, {'entity': \"Crohn's disease\", 'concept_id': 'C0010346', 'confidence': 1.0}], [{'entity': 'Ganglion cells', 'concept_id': 'C0228071', 'confidence': 1.0}, {'entity': 'submucosa', 'concept_id': 'C0225344', 'confidence': 1.0}, {'entity': 'malignancy', 'concept_id': 'C0006826', 'confidence': 1.0}], [{'entity': 'Ganglion cells', 'concept_id': 'C0228071', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'congenital megacolon', 'concept_id': 'C0019569', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_12",
"caption_rating": "9"
},
{
"": "1008050",
"caption": "Hyperchromatic cells have mainly heterochromatin and appear very dark.",
"image_path": "Wiyo6taYRF4_image_8ec240a1-cd99-485c-8390-b36b49277f89.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Hematopathology', 'Neuropathology', 'Cytopathology']",
"roi_text": "['Appearance of heterochromatin and euchromatin in the nucleus.', 'Plasma cells as a reference for classifying nuclear features.', 'Example of vesicular nuclei.']",
"noisy_text": " whether it is vesicular, or it is salt and pepper-like. So these are the different nuclear features which are characterized. And how are you going to differentiate these nuclear features? So let's see some of the nuclear features. And before we move on to describe these features, I think the first thing that we should look at and understand what we are meaning by hyperchromasia and vesicularism is to look at a plasma cell. So a plasma cell is the best example, and it is the best reference where you can classify the different nuclear features. So if you look carefully, the plasma cell has got a cartwheel-like of an appearance. So it is called cartwheel because you see some areas which are darkly strained. So they are the high heterochromatin areas, that is the darkly strained areas. And then in some areas, you see that there is light straining, which is the euchromatin area. So basically, the chromatin that we see in the nucleus is of two types, heterochromatin and euchromatin. Heterochromatin is going to appear darker, whereas the euchromatin will appear lighter on the cell. So similarly, when we see here in this cell nucleus, we see that there are dark and lightly strained areas. And this is what we call as heterochromatin and euchromatin. So suppose in a cell which has mainly heterochromatin, so the entire nucleus is going to look very dark. So those are the cells that we are going to call as hyperchromatic. And if a nucleus is composed of mainly euchromatin, then it will look very lightly strained. And this is what we call as vesicular nuclei. Now to know here what is important is that in a vesicular nuclei, the nucleus is very actively dividing. So if you have not a vesicular nuclei, that in itself will tell you that the cell is very actively proliferating. So let's see one example of vesicular nuclei here. So these",
"corrected_text": " whether it is vesicular, or it is salt and pepper-like. So these are the different nuclear features which are characterized. And how are you going to differentiate these nuclear features? So let's see some of the nuclear features. And before we move on to describe these features, I think the first thing that we should look at and understand what we are meaning by hyperchromasia and vesicular nuclei is to look at a plasma cell. So a plasma cell is the best example, and it is the best reference where you can classify the different nuclear features. So if you look carefully, the plasma cell has got a cartwheel-like of an appearance. So it is called cartwheel because you see some areas which are darkly strained. So they are the high heterochromatin areas, that is the darkly strained areas. And then in some areas, you see that there is light straining, which is the euchromatin area. So basically, the chromatin that we see in the nucleus is of two types, heterochromatin and euchromatin. Heterochromatin is going to appear darker, whereas the euchromatin will appear lighter on the cell. So similarly, when we see here in this cell nucleus, we see that there are dark and lightly strained areas. And this is what we call as heterochromatin and euchromatin. So suppose in a cell which has mainly heterochromatin, so the entire nucleus is going to look very dark. So those are the cells that we are going to call as hyperchromatic. And if a nucleus is composed of mainly euchromatin, then it will look very lightly strained. And this is what we call as vesicular nuclei. Now to know here what is important is that in a vesicular nuclei, the nucleus is very actively dividing. So if you have not a vesicular nuclei, that in itself will tell you that the cell is very actively proliferating. So let's see one example of vesicular nuclei here. So these",
"med_umls_ids": "[[{'entity': 'nuclear', 'concept_id': 'C0521447', 'confidence': 1.0}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'vesicular', 'concept_id': 'C0205378', 'confidence': 1.0}, {'entity': 'salt', 'concept_id': 'C0036140', 'confidence': 1.0}, {'entity': 'pepper-like', 'concept_id': 'C2828772', 'confidence': 0.6665787696838379}], [{'entity': 'Plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'nuclear features', 'concept_id': 'C0521447', 'confidence': 0.6837654709815979}], [{'entity': 'Chromatin', 'concept_id': 'C0008546', 'confidence': 1.0}, {'entity': 'nucleus', 'concept_id': 'C0007610', 'confidence': 1.0}, {'entity': 'heterochromatin', 'concept_id': 'C0019397', 'confidence': 1.0}, {'entity': 'euchromatin', 'concept_id': 'C0059882', 'confidence': 1.0}], [{'entity': 'Hyperchromatic cells', 'concept_id': 'C0333911', 'confidence': 0.823300302028656}, {'entity': 'heterochromatin', 'concept_id': 'C0019397', 'confidence': 1.0}, {'entity': 'very dark', 'concept_id': 'C0332582', 'confidence': 0.8206402063369751}], [{'entity': 'Vesicular nuclei', 'concept_id': 'C2325471', 'confidence': 0.7651268839836121}, {'entity': 'cell', 'concept_id': 'C0007634', 'confidence': 1.0}, {'entity': 'dividing', 'concept_id': 'C0332849', 'confidence': 1.0}, {'entity': 'euchromatin', 'concept_id': 'C0059882', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1152.0",
"id": "test_13",
"caption_rating": "7"
},
{
"": "1007651",
"caption": "Coalescence of remnant cell walls of adipocytes seen at the periphery of the fat microcysts.",
"image_path": "hoV-JkD6Wb0_image_ae24eba8-c8b9-412b-9009-f7ba4d5b0c4a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['Large fat microcysts', 'Membranous lipodystrophy at the periphery of the fat microcysts', 'Arabesque-type fibular material at the periphery of the fat microcysts', 'Remnant cell walls of adipocytes at the periphery of the fat microcysts', 'Large fat microcysts', 'Membranous lipodystrophy at the periphery of the fat microcysts', 'Arabesque-type fibular material at the periphery of the fat microcysts', 'Remnant cell walls of adipocytes at the periphery of the fat microcysts']",
"noisy_text": " inflammation. There aren't many viable adipocytes left here. A lot of the adipocytes have kind of ruptured and fused, and so we've got these large fat microcysts, and if we look at the periphery of the fat microcyst, we've got this lipomembranous change, this kind of arabesque-type fibular material out at the periphery, which basically represents coalescence of remnant cell walls of adipocytes. In addition, within the surrounding tissue, there's a little bit of fibrosis. There are a few lipophages and a very sparse infiltrative",
"corrected_text": " inflammation. There aren't many viable adipocytes left here. A lot of the adipocytes have kind of ruptured and fused, and so we've got these large fat microcysts, and if we look at the periphery of the fat microcyst, we've got this lipomembranous change, this kind of arabesque-type fibular material out at the periphery, which basically represents coalescence of remnant cell walls of adipocytes. In addition, within the surrounding tissue, there's a little bit of fibrosis. There are a few lipophages and a very sparse infiltrative",
"med_umls_ids": "[[{'entity': 'Inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}], [{'entity': 'adipocytes', 'concept_id': 'C0206131', 'confidence': 1.0}, {'entity': 'left', 'concept_id': 'C0205091', 'confidence': 1.0}], [{'entity': 'fat microcysts', 'concept_id': 'C1513269', 'confidence': 0.871767520904541}], [{'entity': 'Membranous lipodystrophy', 'concept_id': 'C0406599', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'fat microcysts', 'concept_id': 'C1513269', 'confidence': 0.871767520904541}], [{'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'fat microcysts', 'concept_id': 'C1513269', 'confidence': 0.871767520904541}], [{'entity': 'Coalescence', 'concept_id': 'C4727092', 'confidence': 0.8749340176582336}, {'entity': 'remnant', 'concept_id': 'C3272697', 'confidence': 1.0}, {'entity': 'cell walls', 'concept_id': 'C0007623', 'confidence': 1.0}, {'entity': 'adipocytes', 'concept_id': 'C0206131', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'fat microcysts', 'concept_id': 'C1513269', 'confidence': 0.871767520904541}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_14",
"caption_rating": "8"
},
{
"": "1008023",
"caption": "Description of a large punch biopsy with an infiltrate filling the dermis and extending into the subcutaneous tissue.",
"image_path": "8S4LeiO6Bbk_image_d9437f71-99a7-4b21-84d6-8af77c47cabf.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['infiltrate filling the dermis and extending into the subcutaneous tissue', 'cellular infiltrate throughout the dermis', 'infiltrate filling the dermis and extending into the subcutaneous tissue', 'brown pigment near the surface', 'hyperplastic epidermis', 'cellular infiltrate throughout the dermis']",
"noisy_text": " a large punch biopsy. And I think this actually was two punch biopsies from one lesion, each one bisected. And we can see that we've got an infiltrate filling the dermis and extending into the subcutaneous tissue. The infiltrate appears to be compressing the fat rather than growing in between the adipocytes. And I think it's scanning magnification, you know, one of the things that you can really begin to appreciate, not only the fact that this lesion is partially sampled, that it extends to the base and edges of the specimen, but one can begin to appreciate abundant hemorrhage within this tumor. And in addition, we can see some brown pigment near the surface. And common sense will tell you where there's smoke, there's fire. Since we do have all this abundant hemorrhage, there's a high probability that the pigment, this brownish gold pigment that we're seeing up near the surface of the specimen is likely hemocentaurant rather than melanin. But we'll confirm that when we go down to a higher power. As we move in, we can see that the epidermis is slightly hyperplastic. We've got this cellular infiltrate throughout the dermis and we'll need to go down and take a look at this infiltrate. It appears a little less dense at the",
"corrected_text": " a large punch biopsy. And I think this actually was two punch biopsies from one lesion, each one bisected. And we can see that we've got an infiltrate filling the dermis and extending into the subcutaneous tissue. The infiltrate appears to be compressing the fat rather than growing in between the adipocytes. And I think it's scanning magnification, you know, one of the things that you can really begin to appreciate, not only the fact that this lesion is partially sampled, that it extends to the base and edges of the specimen, but one can begin to appreciate abundant hemorrhage within this tumor. And in addition, we can see some brown pigment near the surface. And common sense will tell you where there's smoke, there's fire. Since we do have all this abundant hemorrhage, there's a high probability that the pigment, this brownish gold pigment that we're seeing up near the surface of the specimen is likely hemocentaurant rather than melanin. But we'confirm that when we go down to a higher power. As we move in, we can see that the epidermis is slightly hyperplastic. We've got this cellular infiltrate throughout the dermis and we'll need to go down and take a look at this infiltrate. It appears a little less dense at the",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'punch biopsy', 'concept_id': 'C0182557', 'confidence': 1.0}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'filling', 'concept_id': 'C0178866', 'confidence': 0.7777882218360901}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'subcutaneous tissue', 'concept_id': 'C0222331', 'confidence': 1.0}], [{'entity': 'Excessive', 'concept_id': 'C0442802', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'brown pigment near', 'concept_id': 'C4555503', 'confidence': 0.865685760974884}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}], [{'entity': 'hyperplastic epidermis', 'concept_id': 'C4748317', 'confidence': 0.7633129358291626}, {'entity': 'cellular infiltrate', 'concept_id': 'C1692321', 'confidence': 1.0}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_15",
"caption_rating": "9"
},
{
"": "1007785",
"caption": "Caution against taking superficial shave biopsies of DFSPs and recommendation for deep incisional biopsy when dealing with a soft tissue neoplasm.",
"image_path": "LlPaENuqzVQ_image_9446bc04-9735-48c9-93ba-e37e9c7fca35.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['Storiform pattern', 'Ring chromosome', 'Collagen A', 'Platelet-derived growth factor', 'Soft tissue neoplasm']",
"noisy_text": " you do have the nice, beautiful storiform pattern here. And you don't really need a CD34 stain here. You can do it if you want to, if you like to sort of charge patients extra money, but this is a classic DFSB. And that ring chromosome, the collagen A, platelet-derived growth factor, the translocation is classic for that. And one other thing, if you biopsy the surface of DFSB, sometimes it can look like a neurofibroma. So beware of taking superficial shave biopsies of DFSBs. You need to take a deep incisional biopsy. Whenever you're dealing with a soft tissue neoplasm and dermatology, get out the knife and fork. Don't get the punch biopsy out. Don't ever do a shave on it. So you got to take a real biopsy when you're dealing with a soft tissue neoplasm because of",
"corrected_text": " you do have the nice, beautiful storiform pattern here. And you don't really need a CD34 stain here. You can do it if you want to, if you like to sort of charge patients extra money, but this is a classic DFSP. And that ring chromosome, the collagen A, platelet-derived growth factor, the translocation is classic for that. And one other thing, if you biopsy the surface of DFSP, sometimes it can look like a neurofibroma. So beware of taking superficial shave biopsies of DFSBs. You need to take a deep incisional biopsy. Whenever you're dealing with a soft tissue neoplasm and dermatology, get out the knife and fork. Don't get the punch biopsy out. Don't ever do a shave on it. So you got to take a real biopsy when you're dealing with a soft tissue neoplasm because of",
"med_umls_ids": "[[{'entity': 'Identification', 'concept_id': 'C0020792', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}, {'entity': 'storiform pattern', 'concept_id': 'C1336510', 'confidence': 0.8142904043197632}, {'entity': 'ring chromosome', 'concept_id': 'C0035639', 'confidence': 1.0}, {'entity': 'collagen A', 'concept_id': 'C0009325', 'confidence': 0.9128584265708923}, {'entity': 'platelet-derived growth factor', 'concept_id': 'C0032200', 'confidence': 1.0}, {'entity': 'translocation', 'concept_id': 'C0040715', 'confidence': 1.0}], [{'entity': 'Caution', 'concept_id': 'C1882442', 'confidence': 0.7039048671722412}, {'entity': 'superficial', 'concept_id': 'C0205124', 'confidence': 1.0}, {'entity': 'DFSPs', 'concept_id': 'C0334464', 'confidence': 0.8083938360214233}, {'entity': 'recommendation', 'concept_id': 'C0034866', 'confidence': 1.0}, {'entity': 'deep incisional biopsy', 'concept_id': 'C0184922', 'confidence': 0.8345454335212708}, {'entity': 'dealing', 'concept_id': 'C0556449', 'confidence': 0.7019717693328857}, {'entity': 'soft tissue neoplasm', 'concept_id': 'C0037579', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_16",
"caption_rating": "9"
},
{
"": "1007023",
"caption": "Disseminated GA in older individuals may be a perineoplastic process.",
"image_path": "udoW6VSqsm4_image_95719a02-3a3f-4588-8a77-58a6dc65c44c.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['small individual papules', 'central crust', 'perioral skin', 'granulomatous condition', 'palisade granulostermatitis', 'neutrophilic dermatosis', 'older individuals', 'perineoplastic process']",
"noisy_text": " Yeah, this would be more kind of the classic one, probably. What else? Here's the classic one clinically. What if there's small individual papules that have a central crust in them, often on apral skin? We have had several cases of the disseminated GA, but I'm not sure if they didn't have a crust. So, what's the type that had it? Perforating? Perforating GA. Perforating GA, good. So, this was granulomanuary. There's one other condition that gives you palisade granulostermatitis like this, but it also gives you some neutrophils infiltrate. That palisade and neutrophilic granulostermatitis, that's another thing that you at least have to think about when you see GA. If you see an older person that's got disseminated GA, think about it as a perineoplastic process. Sometimes you",
"corrected_text": " Yeah, this would be more kind of the classic one, probably. What else? Here's the classic one clinically. What if there's small individual papules that have a central crust in them, often on perioral skin? We have had several cases of the disseminated GA, but I'm not sure if they didn't have a crust. So, what's the type that had it? Perforating? Perforating GA. Perforating GA, good. So, this was granulomatous. There's one other condition that gives you palisade granulostermatitis like this, but it also gives you some neutrophils infiltrate. That palisade and neutrophilic dermatosis, that's another thing that you at least have to think about when you see GA. If you see an older person that's got disseminated GA, think about it as a perineoplastic process. Sometimes you",
"med_umls_ids": "[[{'entity': 'Clinical', 'concept_id': 'C0205210', 'confidence': 1.0}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'skin condition', 'concept_id': 'C1719933', 'confidence': 1.0}, {'entity': 'individual', 'concept_id': 'C0027361', 'confidence': 1.0}, {'entity': 'papules', 'concept_id': 'C0332563', 'confidence': 0.9999999403953552}, {'entity': 'central crust', 'concept_id': 'C0205204', 'confidence': 0.7633819580078125}, {'entity': 'perioral skin', 'concept_id': 'C0448802', 'confidence': 0.8075158596038818}], [{'entity': 'Perforating', 'concept_id': 'C0549099', 'confidence': 1.0}, {'entity': 'GA', 'concept_id': 'C0002915', 'confidence': 1.0}, {'entity': 'granulomatous condition', 'concept_id': 'C0439667', 'confidence': 0.8219265341758728}, {'entity': 'palisade', 'concept_id': 'C0331512', 'confidence': 0.8241410255432129}, {'entity': 'granulostermatitis', 'concept_id': 'C0743086', 'confidence': 0.7311265468597412}], [{'entity': 'Neutrophilic dermatosis', 'concept_id': 'C1142272', 'confidence': 1.0}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'GA', 'concept_id': 'C0002915', 'confidence': 1.0}], [{'entity': 'Disseminated', 'concept_id': 'C0205221', 'confidence': 1.0}, {'entity': 'GA', 'concept_id': 'C0002915', 'confidence': 1.0}, {'entity': 'older', 'concept_id': 'C0337524', 'confidence': 0.7771234512329102}, {'entity': 'individuals', 'concept_id': 'C0027361', 'confidence': 0.8766164779663086}, {'entity': 'perineoplastic process', 'concept_id': 'C0027671', 'confidence': 0.8771522045135498}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_17",
"caption_rating": "7"
},
{
"": "1007465",
"caption": "A skin biopsy has been completely excised and the lesion is diagnosed as molluscum contagiosum, which is a contagious virus.",
"image_path": "1DP288T6QqU_image_f62c58cd-e7eb-4ea7-b220-a3ed86537d46.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Pediatric']",
"roi_text": "['Cut skin biopsy', 'Lesion diagnosed as molluscum contagiosum', 'Cut skin biopsy', 'Lesion diagnosed as molluscum contagiosum', 'Cut skin biopsy', 'Lesion diagnosed as molluscum contagiosum']",
"noisy_text": " And the other side of this cut skin biopsy looks exactly the same. Also notice that the parts of the normal skin around it look fairly normal. And specifically, this lesion has been completely excised. It's almost a shame to diagnose this lesion in terms of cells and stuff like that. I will. But let me tell you, there is nothing else in the world on the skin that looks like this. And even inexperienced dermatologists and inexperienced pathologists can take a look at this. And bingo, they say instantly, molluscum contagiosum. It's a virus. And it's contagious. And that's why they call it molluscum contagiosum. I'm going to describe it in more particular language anyway. Notice how",
"corrected_text": " And the other side of this cut skin biopsy looks exactly the same. Also notice that the parts of the normal skin around it look fairly normal. And specifically, this lesion has been completely excised. It's almost a shame to diagnose this lesion in terms of cells and stuff like that. I will. But let me tell you, there is nothing else in the world on the skin that looks like this. And even inexperienced dermatologists and inexperienced pathologists can take a look at this. And bingo, they say instantly, molluscum contagiosum. It's a virus. And it's contagious. And that's why they call it molluscum contagiosum. I'm going to describe it in more particular language anyway. Notice how",
"med_umls_ids": "[[{'entity': 'skin biopsy', 'concept_id': 'C0150866', 'confidence': 0.9999999403953552}, {'entity': 'excised', 'concept_id': 'C1444670', 'confidence': 0.7215964794158936}, {'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'diagnosed', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'molluscum contagiosum', 'concept_id': 'C0026393', 'confidence': 1.0}, {'entity': 'contagious virus', 'concept_id': 'C0029200', 'confidence': 0.7398762106895447}]]",
"magnification": "0.0",
"height": "720.0",
"width": "760.0",
"id": "test_18",
"caption_rating": "8"
},
{
"": "1008339",
"caption": "Abnormal maturation of keratinocytes with full thickness keratinocytic atypia and hyperchromatic cells within the stratum corneum.",
"image_path": "8S4LeiO6Bbk_image_e9947037-d23a-421e-a41c-750914e5a706.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['abnormal maturation of keratinocytes', 'hyperchromatic cells', 'melanin pigment', 'dendritic melanocytes', 'abnormal maturation of keratinocytes', 'hyperchromatic cells', 'melanin pigment', 'dendritic melanocytes', 'abnormal maturation of keratinocytes', 'hyperchromatic cells', 'melanin pigment', 'dendritic melanocytes']",
"noisy_text": " I think would be reasonable considerations. However, if we move to higher power and begin to study the epidermis a little bit more carefully we can see that there's clear-cut abnormal maturation here. We've got full thickness keratinocytic atypia with nucleic acid or pleomorphic and hyperchromatic. There is abnormal maturation with even abnormal hyperchromatic perikaratotic cells within the stratum corneum. There's an increased amount of melanin pigment pressed within the basal layer and we can see that we've got an increased amount of melanin pigment and even a few dendritic melanocytes within the epidermis and so what we've got here is an example of pigmented Bowen's disease or pigmented squamous cell carcinoma. One could see similar changes in lesions",
"corrected_text": " I think would be reasonable considerations. However, if we move to higher power and begin to study the epidermis a little bit more carefully we can see that there's clear-cut abnormal maturation of keratinocytes here. We've got full thickness keratinocytic atypia with nucleic acid or pleomorphic and hyperchromatic. There is abnormal maturation with even abnormal hyperchromatic parakeratotic cells within the stratum corneum. There's an increased amount of melanin pigment pressed within the basal layer and we can see that we've got an increased amount of melanin pigment and even a few dendritic melanocytes within the epidermis and so what we've got here is an example of pigmented Bowen 's disease's disease or pigmented squamous cell carcinoma. One could see similar changes in lesions",
"med_umls_ids": "[[{'entity': 'Abnormal', 'concept_id': 'C0205161', 'confidence': 1.0}, {'entity': 'maturation', 'concept_id': 'C0678723', 'confidence': 1.0}, {'entity': 'keratinocytes', 'concept_id': 'C0022567', 'confidence': 1.0}, {'entity': 'thickness', 'concept_id': 'C1280412', 'confidence': 1.0}, {'entity': 'keratinocytic atypia', 'concept_id': 'C0741302', 'confidence': 0.6335055828094482}, {'entity': 'hyperchromatic cells', 'concept_id': 'C0333911', 'confidence': 0.823300302028656}, {'entity': 'stratum corneum', 'concept_id': 'C0221921', 'confidence': 1.0}], [{'entity': 'Increased', 'concept_id': 'C0205217', 'confidence': 1.0}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}, {'entity': 'pigment', 'concept_id': 'C0031911', 'confidence': 1.0}, {'entity': 'dendritic melanocytes', 'concept_id': 'C0025201', 'confidence': 0.7694142460823059}, {'entity': 'epidermis', 'concept_id': 'C0014520', 'confidence': 1.0}], [{'entity': 'Diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'Bowen\u2019s disease', 'concept_id': 'C0006079', 'confidence': 0.9730859994888306}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'squamous cell carcinoma', 'concept_id': 'C0007137', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_19",
"caption_rating": "9"
},
{
"": "1009071",
"caption": "Mitotic activity is present.",
"image_path": "iklRyY1nBIE_image_c49b67e3-332c-4010-98ee-fa3925d7a0cc.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['Wild tumor with bad nuclei', 'Mitotic activity', 'Epithelial and spindle cell component', 'Pain cocktail stain']",
"noisy_text": " We need to exclude these two. And I'll just let you all take a look at this and try and figure out what's going on. So this looks like another wild tumor of bad nuclei. If you look carefully, you can see some mitotic activity there. This looks like it has both an epithelial and a stromal component to it, or at least an epithelial and a spindle cell component to it. The epithelial component looks concerning. And if I show you the corresponding stain, that will give it away. This will give the diagnosis away. So this is the pain cocktail. And as you can see, it's negative in the epithelial component for basal cells.",
"corrected_text": " We need to exclude these two. And I'll just let you all take a look at this and try and figure out what's going on. So this looks like another wild tumor of bad nuclei. If you look carefully, you can see some mitotic activity there. This looks like it has both an epithelial and spindle cell component to it, or at least an epithelial and a spindle cell component to it. The epithelial component looks concerning. And if I show you the corresponding stain, that will give it away. This will give the diagnosis away. So this is the pain cocktail. And as you can see, it's negative in the epithelial component for basal cells.",
"med_umls_ids": "[[{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'epithelial', 'concept_id': 'C0221908', 'confidence': 1.0}, {'entity': 'spindle cell', 'concept_id': 'C0682540', 'confidence': 0.9999999403953552}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'epithelial component', 'concept_id': 'C1707933', 'confidence': 0.8783122897148132}], [{'entity': 'Mitotic activity', 'concept_id': 'C1334779', 'confidence': 1.0}], [{'entity': 'pain cocktail', 'concept_id': 'C0678420', 'confidence': 0.9142165184020996}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'epithelial component', 'concept_id': 'C1707933', 'confidence': 0.8783122897148132}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_20",
"caption_rating": "7"
},
{
"": "1005039",
"caption": "Secondary tumors, such as colorectal carcinoma and urothelial carcinoma, can also destroy glands.",
"image_path": "iklRyY1nBIE_image_04cd57c4-7aac-4e75-8e6f-28cd9419e459.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['tumor', 'prostatic urethra', 'inflammatory response']",
"noisy_text": " is colonizing and destroying previously benign glands. And when you see that, it's usually, obviously, you want to exclude an introductory process, colonizing benign glands. But you also want to exclude secondary tumors. Secondary tumors do that, too. Colorectal carcinoma can do that. Urethelial carcinoma can do that. But this specular entity is arising not from the colon, even though it looks like it in areas. It's also not arising from the bladder. This is actually arising from the prostatic urethra. So this is what used to be the prostatic urethra, which has been destroyed by this tumor, because the tumor actually arose from here. I'll show you some early stages of this, early forms of this. This is like an advanced case. You can see there's a very florid host inflammatory response. As you'll",
"corrected_text": " is colonizing and destroying previously benign glands. And when you see that, it's usually, obviously, you want to exclude an introductory process, colonizing benign glands. But you also want to exclude secondary tumors. Secondary tumors do that, too. Colorectal carcinoma can do that. urothelial carcinoma can do that. But this specific entity is arising not from the colon, even though it looks like it in areas. It's also not arising from the bladder. This is actually arising from the prostatic urethra. So this is what used to be the prostatic urethra, which has been destroyed by this tumor, because the tumor actually arose from here. I'll show you some early stages of this, early forms of this. This is like an advanced case. You can see there's a very florid host inflammatory response. As you'll",
"med_umls_ids": "[[{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'colonizing', 'concept_id': 'C1300196', 'confidence': 0.61208176612854}, {'entity': 'destroying', 'concept_id': 'C1948029', 'confidence': 1.0}, {'entity': 'benign glands', 'concept_id': 'C1301287', 'confidence': 0.726940393447876}, {'entity': 'prostatic urethra', 'concept_id': 'C0458450', 'confidence': 1.0}], [{'entity': 'Secondary tumors', 'concept_id': 'C0027627', 'confidence': 0.9999999403953552}, {'entity': 'colorectal carcinoma', 'concept_id': 'C0009402', 'confidence': 0.9999998807907104}, {'entity': 'urothelial carcinoma', 'concept_id': 'C0007138', 'confidence': 1.0}, {'entity': 'destroy', 'concept_id': 'C0681205', 'confidence': 0.9999999403953552}, {'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}], [{'entity': 'host', 'concept_id': 'C1167395', 'confidence': 0.9999999403953552}, {'entity': 'inflammatory response', 'concept_id': 'C1155266', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_21",
"caption_rating": "8"
},
{
"": "1007591",
"caption": "Molecular testing may be necessary if there are marked pleomorphism, high mitotic activity, or other concerning features.",
"image_path": "QDb68_G1HR4_image_2b9d634a-4aee-4dd1-9026-7dbebb1015fc.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " sometimes pleomorphism is seen it's just really uncommon. Also mitotic activity I don't think I mentioned it yet mitoses are usually very very low in this tumor if you see I think the general rule is if you're unless you're a sarcoma pathology expert. And even then if I see even as a sarcoma pathologist if I see marked pleomorphism a lot of mitotic activity other features like that I'm probably going to send the case for molecular testing just to be totally sure that it's a low-grade fiber myxoid sarcoma and not some other mimic. So experts",
"corrected_text": " sometimes pleomorphism is seen it's just really uncommon. Also mitotic activity I don't think I mentioned it yet mitoses are usually very very low in this tumor if you see I think the general rule is if you're unless you're a sarcoma pathology expert. And even then if I see even as a sarcoma pathologist if I see marked pleomorphism a lot of mitotic activity other features like that I'm probably going to send the case for molecular testing just to be totally sure that it's a low-grade fiber myxoid sarcoma and not some other mimic. So experts",
"med_umls_ids": "[[{'entity': 'Pleomorphism', 'concept_id': 'C0032219', 'confidence': 1.0}, {'entity': 'mitotic activity', 'concept_id': 'C1334779', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}], [{'entity': 'Mitoses', 'concept_id': 'C0026255', 'confidence': 1.0}], [{'entity': 'Molecular testing', 'concept_id': 'C1521991', 'confidence': 0.8002516627311707}, {'entity': 'pleomorphism', 'concept_id': 'C0032219', 'confidence': 1.0}, {'entity': 'mitotic activity', 'concept_id': 'C1334779', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_22",
"caption_rating": "8"
},
{
"": "1006544",
"caption": "Smaller chorionic villi are visible towards the maternal site.",
"image_path": "PJX3uZ7fRn4_image_f749ca24-e5b0-46f3-ac60-273091bcb4e3.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gynecologic', 'Soft tissue', 'Hematopathology']",
"roi_text": "['vascular channels', 'chorionic villi', 'calcification', 'vascular channels', 'chorionic villi', 'calcification']",
"noisy_text": " This is a section from placenta which shows a large irregular area with proliferation of thin walled vascular channels of variable size towards the fetal surface of placenta. Smaller chorionic villi can be seen towards the maternal site. Higher magnification of the same showing large vascular channels in the chorion filled with blood. Still higher magnification showing intercommunicating slit-like vascular spaces in the mass. Focal area of calcification can be seen in the tumor. Still another area",
"corrected_text": " This is a section from placenta which shows a large irregular area with proliferation of thin walled vascular channels of variable size towards the fetal surface of placenta. smaller chorionic villi are not incorrect can be seen towards the maternal site. Higher magnification of the same showing large vascular channels in the chorion filled with blood. Still higher magnification showing intercommunicating slit-like vascular spaces in the mass. Focal area of calcification can be seen in the tumor. Still another area",
"med_umls_ids": "[[{'entity': 'Proliferation', 'concept_id': 'C0334094', 'confidence': 1.0}, {'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}, {'entity': 'variable size', 'concept_id': 'C1866144', 'confidence': 0.8559831976890564}, {'entity': 'fetal', 'concept_id': 'C0015965', 'confidence': 1.0}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'placenta', 'concept_id': 'C0032043', 'confidence': 1.0}], [{'entity': 'chorionic villi', 'concept_id': 'C0008508', 'confidence': 1.0}, {'entity': 'maternal site', 'concept_id': 'C0026591', 'confidence': 0.7640593647956848}], [{'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}, {'entity': 'chorion', 'concept_id': 'C0008503', 'confidence': 0.9999998807907104}, {'entity': 'blood', 'concept_id': 'C0005767', 'confidence': 1.0}], [{'entity': 'Intercommunicating', 'concept_id': 'C0205196', 'confidence': 0.8271207213401794}, {'entity': 'vascular spaces', 'concept_id': 'C0225983', 'confidence': 0.819495439529419}, {'entity': 'mass', 'concept_id': 'C0577559', 'confidence': 1.0}], [{'entity': 'Focal area', 'concept_id': 'C0205234', 'confidence': 0.7634891271591187}, {'entity': 'calcification', 'concept_id': 'C0006660', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_23",
"caption_rating": "7"
},
{
"": "1006044",
"caption": "No mitotic triggers found, no need for immunohistochemistry. HMB-45 and Ki-67 tests could be done but not necessary.",
"image_path": "zhzJ9pgCvuw_image_92f6b2f2-f755-4907-a53c-f332759a7245.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " looking for mitotic triggers but uh they they they will be there if not in this section they'll be present in the next section and i don't think you need to do any immunohistochemistry on this case it's that's just what it is a lot of people get on search and then they think gosh i need to do something so what you could do if you really wanted to you could do an hmb 45 and you'd find probably all of this infiltrators expresses hmb 45 you could do a key 67 and you'd find you know a very brisk positivity or you probably would i find cyclin d1 is much",
"corrected_text": " looking for mitotic triggers but uh they they they will be there if not in this section they'll be present in the next section and i don't think you need to do any immunohistochemistry on this case it's that's just what it is a lot of people get on search and then they think gosh i need to do something so what you could do if you really wanted to you could do an HMB-45 and you'd find probably all of this infiltrators expresses HMB-45 you could do a Ki-67 and you'd find you know a very brisk positivity or you probably would i find cyclin d1 is much",
"med_umls_ids": "[[{'entity': 'mitotic', 'concept_id': 'C1513354', 'confidence': 1.0}, {'entity': 'triggers', 'concept_id': 'C0032930', 'confidence': 1.0}, {'entity': 'immunohistochemistry', 'concept_id': 'C0021044', 'confidence': 0.9999998807907104}, {'entity': 'HMB-45', 'concept_id': 'C1440756', 'confidence': 1.0}, {'entity': 'Ki-67 tests', 'concept_id': 'C0022885', 'confidence': 0.536566972732544}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_24",
"caption_rating": "7"
},
{
"": "1008372",
"caption": "The dermal infiltrate is composed entirely of lymphocytes, with a few extravasated erythrocytes in some areas, suggestive of pityriasis lichenoides.",
"image_path": "8S4LeiO6Bbk_image_c658e2d5-2f96-4420-8deb-ba2464e369ea.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Infiltrate within the dermis composed entirely of lymphocytes.', 'Few extravasated erythrocytes in some areas.', 'Few extravasated erythrocytes in some areas.', 'Infiltrate within the dermis composed entirely of lymphocytes.', 'Few extravasated erythrocytes in some areas.', 'Fragmented biopsy specimen with bluish stain.']",
"noisy_text": " and if we look at the infiltrate within the dermis, we can see that it's composed entirely of lymphocytes. In some areas, there were a few extravasated erythrocytes, a few of which were carried up into the overlying epidermis. This constellation of findings is most suggestive of pittoriasis liganoides. Clinically, this patient had PLC, or pittoriasis liganoides chronica. I tend to view pittoriasis liganoides as running along a spectrum. A lot of times, we'll refer to the entire spectrum as Leuka Habermann disease, with pittoriasis liganoides chronica being on the one end of the spectrum, and pleva being on the other end of the spectrum, PLC being characterized by more scaly macules or scaly papules, and pleva being characterized by more crusted and eroded papulonecrotic type lesions. But the histology of the two conditions is actually quite similar. It's a matter of degree. With pleva, you're more likely the acute form of the condition to see more spongiosis, ballooning, necrosis, a denser infiltrate, more necrotics along the DEJ, pericaratosis containing neutrophils. With PLC, similar findings, just a little more blunt. The inflammatory infiltrate may be present around the superficial plexus only. One usually can see some pericaratosis, but there aren't as many necrotic keratinocytes along the DEJ, and a lot of times, the alterations within the epidermis are more subtle. But this was an example of biopsy from a patient with clinically documented pittoriasis like in wades clonica. Moving on to slide number 10. This was, I thought, a really cool case. This was a fragmented biopsy specimen, and you can see that the stain is quite bluish. I can't",
"corrected_text": " and if we look at the infiltrate within the dermis, we can see that it's composed entirely of lymphocytes. In some areas, there were a few extravasated erythrocytes, a few of which were carried up into the overlying epidermis. This constellation of findings is most suggestive of pityriasis lichenoides. Clinically, this patient had PLC, or pityriasis lichenoides chronica. I tend to view pityriasis lichenoides as running along a spectrum. A lot of times, we'refer to the entire spectrum as Leuka Habermann disease, with pityriasis lichenoides chronica being on the one end of the spectrum, and pleva being on the other end of the spectrum, PLC being characterized by more scaly macules or scaly papules, and pleva being characterized by more crusted and eroded papulonecrotic type lesions. But the histology of the two conditions is actually quite similar. It's a matter of degree. With pleva, you're more likely the acute form of the condition to see more spongiosis, ballooning, necrosis, a denser infiltrate, more necrotic along the DEJ, parakeratosis containing neutrophils. With PLC, similar findings, just a little more blunt. The inflammatory infiltrate may be present around the superficial plexus only. One usually can see some parakeratosis, but there aren't as many necrotic keratinocytes along the DEJ, and a lot of times, the alterations within the epidermis are more subtle. But this was an example of biopsy from a patient with clinically documented pittoriasis like in chronica. Moving on to slide number 10. This was, I thought, a really cool case. This was a fragmented biopsy specimen, and you can see that the stain is quite bluish. I can't",
"med_umls_ids": "[[{'entity': 'dermal infiltrate', 'concept_id': 'C0332448', 'confidence': 0.8524853587150574}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'extravasated', 'concept_id': 'C0015376', 'confidence': 0.868863582611084}, {'entity': 'erythrocytes', 'concept_id': 'C0014772', 'confidence': 1.0}, {'entity': 'areas', 'concept_id': 'C0205146', 'confidence': 1.0}, {'entity': 'pityriasis', 'concept_id': 'C0032024', 'confidence': 0.9999998807907104}, {'entity': 'lichenoides', 'concept_id': 'C0443248', 'confidence': 0.8475416302680969}], [{'entity': 'Pityriasis lichenoides', 'concept_id': 'C0162853', 'confidence': 1.0}, {'entity': 'running', 'concept_id': 'C0035953', 'confidence': 1.0}, {'entity': 'spectrum', 'concept_id': 'C1883073', 'confidence': 1.0}, {'entity': 'pityriasis lichenoides chronica', 'concept_id': 'C0162851', 'confidence': 1.0}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'scaly macules', 'concept_id': 'C0332573', 'confidence': 0.7616965174674988}, {'entity': 'papules', 'concept_id': 'C0332563', 'confidence': 0.9999999403953552}], [{'entity': 'histology', 'concept_id': 'C0019638', 'confidence': 1.0}, {'entity': 'pityriasis lichenoides', 'concept_id': 'C0162853', 'confidence': 1.0}, {'entity': 'pleva', 'concept_id': 'C0162852', 'confidence': 1.0}, {'entity': 'pleva', 'concept_id': 'C0162852', 'confidence': 1.0}, {'entity': 'acute', 'concept_id': 'C0205178', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'spongiosis', 'concept_id': 'C0702120', 'confidence': 1.0}, {'entity': 'ballooning', 'concept_id': 'C0004704', 'confidence': 1.0}, {'entity': 'necrosis', 'concept_id': 'C0027540', 'confidence': 1.0}], [{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'clinically documented', 'concept_id': 'C1828480', 'confidence': 0.814785361289978}, {'entity': 'pityriasis lichenoides chronica', 'concept_id': 'C0162851', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_25",
"caption_rating": "9"
},
{
"": "1004736",
"caption": "Lamina propria is hyalinized with some architectural distortion.",
"image_path": "sDFjOtMAYrk_image_a2bbf82c-4704-4b6c-b9dc-1bbb2411ba4e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['Dilated vessels running parallel to the epithelial surface.']",
"noisy_text": " This patient had a history of radiation also for prostate cancer, but the pattern is a little bit different. Yes, the lamina propria is a little bit hyalinized and maybe there's some architectural distortion, but it looks less striking than the other one. And you don't have a good, juicy, hyalinized vessel to really tip you off, but you have another finding to tip you off. And that would be this. These dilated vessels that run parallel to the epithelial surface. And you'll see dilated vessels. Oh, this is a good one right here. Dilated vessels that tend to run parallel to the epithelial",
"corrected_text": " This patient had a history of radiation also for prostate cancer, but the pattern is a little bit different. Yes, the lamina propria is a little bit hyalinized and maybe there's some architectural distortion, but it looks less striking than the other one. And you don't have a good, juicy, hyalinized vessel to really tip you off, but you have another finding to tip you off. And that would be this. These dilated vessels that run parallel to the epithelial surface. And you'll see dilated vessels. Oh, this is a good one right here. Dilated vessels that tend to run parallel to the epithelial",
"med_umls_ids": "[[{'entity': 'Patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'history', 'concept_id': 'C0019664', 'confidence': 1.0}, {'entity': 'radiation', 'concept_id': 'C0034519', 'confidence': 1.0}, {'entity': 'prostate cancer', 'concept_id': 'C0376358', 'confidence': 1.0}], [{'entity': 'Lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'hyalinized', 'concept_id': 'C0332230', 'confidence': 1.0}, {'entity': 'architectural distortion', 'concept_id': 'C2826609', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'dilated vessels running', 'concept_id': 'C0424830', 'confidence': 0.6464064121246338}, {'entity': 'epithelial surface', 'concept_id': 'C2327105', 'confidence': 0.9104864597320557}, {'entity': 'finding', 'concept_id': 'C0037088', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_26",
"caption_rating": "8"
},
{
"": "1008122",
"caption": "Tuberculoid form of leprosy can cause sarcoid granulomatous inflammation.",
"image_path": "udoW6VSqsm4_image_be0b36f7-3f7b-40b6-9863-de9ec37c56d8.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['sarcoid granulomatous inflammation', 'involvement around nerves']",
"noisy_text": " That's the tuberculoid. Yeah, good. The tuberculoid form of leprosy gives you sarcoidal granulomatous inflammation. It's elongated. Very good. That's exactly right. What else can give you sarcoidal granulomatous inflammation? Can I ask a quick question about the sarcoid with the two... The nansins? So, I had a case, I saw a case that looked kind of horizontal, but it was sarcoid. And so, what other ways can you tell? Sometimes it can be difficult, but usually you're going to see involvement around nerves damaged nerves. You're about to get sarcoidal granulomatous inflammation. They always have very high risk inflammatory reactions. They just wipe out the nerves. So, that's helpful. Wasn't",
"corrected_text": " That's the tuberculoid. Yeah, good. The tuberculoid form of leprosy gives you sarcoidal granulomatous inflammation. It's elongated. Very good. That's exactly right. What else can give you sarcoidal granulomatous inflammation? Can I ask a quick question about the sarcoid with the two... The sarcoidosis? So, I had a case, I saw a case that looked kind of horizontal, but it was sarcoid. And so, what other ways can you tell? Sometimes it can be difficult, but usually you're going to see involvement around nerves damaged nerves. You're about to get sarcoidal granulomatous inflammation. They always have very high risk inflammatory reactions. They just wipe out the nerves. So, that's helpful. Wasn't",
"med_umls_ids": "[[{'entity': 'Tuberculoid', 'concept_id': 'C0544783', 'confidence': 0.8459237217903137}, {'entity': 'leprosy', 'concept_id': 'C0023343', 'confidence': 1.0}, {'entity': 'sarcoid', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'granulomatous inflammation', 'concept_id': 'C0553697', 'confidence': 1.0}], [{'entity': 'Involvement', 'concept_id': 'C1314939', 'confidence': 1.0}, {'entity': 'damaged nerves', 'concept_id': 'C3887709', 'confidence': 0.8087002038955688}, {'entity': 'sarcoid', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'granulomatous inflammation', 'concept_id': 'C0553697', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_27",
"caption_rating": "8"
},
{
"": "1007582",
"caption": "Likely melanin instead of hemosiderin due to absence of extravasated erythrocytes.",
"image_path": "8S4LeiO6Bbk_image_077e8bb9-a780-4110-846c-1f3fb94842bb.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['melanin', 'basilar keratinocytes', 'epidermis', 'necrotic keratinocytes', 'lymphocytes', 'melanophages', 'trunk extremities']",
"noisy_text": " than the hemocentauric pigment in the centaurifages. It also tends to be a little bit darker staining, but sometimes it can be very difficult, tinctorially, depending upon the staining quality, to use color to distinguish the two, better to use size and context clues. Also note here we don't have any extravasated erythrocytes here, so much more likely to be melanin, and there's an increased melanin in the basilar keratinocytes. Getting back to the case, thin epidermis, bacular change, necrotic keratinocytes along the basal layer, and Apache band-like infiltrate of lymphocytes and numerous melanovagias. And as it turns out, this biopsy specimen is from a Latin American individual with large hyperpigmented patches on the trunk extremities, and this",
"corrected_text": " than the hemosiderin pigment in the centroblasts. It also tends to be a little bit darker staining, but sometimes it can be very difficult, tinctorially, depending upon the staining quality, to use color to distinguish the two, better to use size and context clues. Also note here we don't have any extravasated erythrocytes here, so much more likely to be melanin, and there's an increased melanin in the basilar keratinocytes. Getting back to the case, thin epidermis, basal cell change, necrotic keratinocytes along the basal layer, and Apache band-like infiltrate of lymphocytes and numerous melanovagias. And as it turns out, this biopsy specimen is from a Latin American individual with large hyperpigmented patches on the trunk extremities, and this",
"med_umls_ids": "[[{'entity': 'Increased', 'concept_id': 'C0205217', 'confidence': 1.0}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}, {'entity': 'basilar keratinocytes', 'concept_id': 'C0022567', 'confidence': 0.803361713886261}], [{'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}, {'entity': 'hemosiderin', 'concept_id': 'C0019113', 'confidence': 1.0}, {'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'extravasated', 'concept_id': 'C0015376', 'confidence': 0.868863582611084}, {'entity': 'erythrocytes', 'concept_id': 'C0014772', 'confidence': 1.0}], [{'entity': 'Thin epidermis', 'concept_id': 'C4231265', 'confidence': 1.0}, {'entity': 'vacuolar change', 'concept_id': 'C0010840', 'confidence': 1.0}, {'entity': 'necrotic keratinocytes', 'concept_id': 'C1168187', 'confidence': 0.8123914003372192}, {'entity': 'basal layer', 'concept_id': 'C0221925', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'numerous', 'concept_id': 'C0439064', 'confidence': 1.0}, {'entity': 'melanophages', 'concept_id': 'C3280463', 'confidence': 0.9375340938568115}], [{'entity': 'Biopsy specimen', 'concept_id': 'C0677862', 'confidence': 1.0}, {'entity': 'Latin American', 'concept_id': 'C1553378', 'confidence': 1.0}, {'entity': 'hyperpigmented', 'concept_id': 'C0333615', 'confidence': 1.0}, {'entity': 'patches', 'concept_id': 'C0994894', 'confidence': 1.0}, {'entity': 'trunk', 'concept_id': 'C0225442', 'confidence': 0.9999999403953552}, {'entity': 'extremities', 'concept_id': 'C0015385', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_28",
"caption_rating": "9"
},
{
"": "1009354",
"caption": "Pleomorphism and mitotic activity are uncommon in this tumor.",
"image_path": "QDb68_G1HR4_image_7a59655a-83cd-439d-b918-af37b1dcc063.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " sometimes pleomorphism is seen it's just really uncommon. Also mitotic activity I don't think I mentioned it yet mitoses are usually very very low in this tumor if you see I think the general rule is if you're unless you're a sarcoma pathology expert. And even then if I see even as a sarcoma pathologist if I see marked pleomorphism a lot of mitotic activity other features like that I'm probably going to send the case for molecular testing just to be totally sure that it's a low-grade fiber myxoid sarcoma and not some other mimic. So experts",
"corrected_text": " sometimes pleomorphism is seen it's just really uncommon. Also mitotic activity I don't think I mentioned it yet mitoses are usually very very low in this tumor if you see I think the general rule is if you're unless you're a sarcoma pathology expert. And even then if I see even as a sarcoma pathologist if I see marked pleomorphism a lot of mitotic activity other features like that I'm probably going to send the case for molecular testing just to be totally sure that it's a low-grade fiber myxoid sarcoma and not some other mimic. So experts",
"med_umls_ids": "[[{'entity': 'Pleomorphism', 'concept_id': 'C0032219', 'confidence': 1.0}, {'entity': 'mitotic activity', 'concept_id': 'C1334779', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}], [{'entity': 'Mitoses', 'concept_id': 'C0026255', 'confidence': 1.0}], [{'entity': 'Molecular testing', 'concept_id': 'C1521991', 'confidence': 0.8002516627311707}, {'entity': 'pleomorphism', 'concept_id': 'C0032219', 'confidence': 1.0}, {'entity': 'mitotic activity', 'concept_id': 'C1334779', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_29",
"caption_rating": "8"
},
{
"": "1007974",
"caption": "Neutrophils in the epithelium indicate cryptitis, which may be related to H. pylori infection.",
"image_path": "r7OA0Trj5hQ_image_0c7f536b-7466-42d1-bbd7-da3aff325ad0.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Neutrophils in the epithelium indicating cryptitis', 'Gastric biopsy for H. pylori with crypt abscess', 'Gastric biopsy for H. pylori with crypt abscess']",
"noisy_text": " Please remember, presence of lymphocytes and plasma cells is not a feature of chronicity. But architectural change by the way of irregular size, shape, and distributed glands is an indication of chronicity. Criteria for chronicity. Yeah, you see nicely neutrophils sitting in the epithelium. Can you all see neutrophils sitting in the epithelium? So this is cryptitis. It is stomach, even though I'm using the term. But I just want to know whether you are able to understand or not. This is a gastric biopsy where you have to look for H. pylori because the H. pylori secrete some chemotactic factors for neutrophils. That's why the neutrophils come. And this is a crypt abscess. This is",
"corrected_text": " Please remember, presence of lymphocytes and plasma cells is not a feature of chronicity. But architectural change by the way of irregular size, shape, and distributed glands is an indication of chronicity. Criteria for chronicity. Yeah, you see nicely neutrophils sitting in the epithelium. Can you all see neutrophils sitting in the epithelium? So this is cryptitis. It is stomach, even though I'm using the term. But I just want to know whether you are able to understand or not. This is a gastric biopsy where you have to look for H. pylori because the H. pylori secrete some chemotactic factors for neutrophils. That's why the neutrophils come. And this is a crypt abscess. This is",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'chronicity', 'concept_id': 'C0547045', 'confidence': 1.0}, {'entity': 'architectural', 'concept_id': 'C0003737', 'confidence': 0.8758222460746765}, {'entity': 'changes', 'concept_id': 'C0392747', 'confidence': 1.0}, {'entity': 'gland size', 'concept_id': 'C0426336', 'confidence': 0.8790121674537659}, {'entity': 'shape', 'concept_id': 'C0332479', 'confidence': 1.0}, {'entity': 'distribution', 'concept_id': 'C0037775', 'confidence': 1.0}, {'entity': 'chronicity', 'concept_id': 'C0547045', 'confidence': 1.0}], [{'entity': 'Neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'cryptitis', 'concept_id': 'C1394254', 'confidence': 0.9999998807907104}, {'entity': 'H. pylori infection', 'concept_id': 'C0850666', 'confidence': 0.9999999403953552}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_30",
"caption_rating": "8"
},
{
"": "1004816",
"caption": "Cribriform pattern and loose, edematous, and vascular stroma.",
"image_path": "8S4LeiO6Bbk_image_a0d9ca4b-d2c9-43b5-be52-eea868bbd3fd.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['epithelial tumor', 'cytoplasm', 'vesicular chromatin pattern', 'lymphocytes', 'duct formation', 'epithelial tumor', 'cytoplasm', 'vesicular chromatin pattern', 'lymphocytes', 'duct formation']",
"noisy_text": " If we move to higher power, we can see that we're dealing with an epithelial rather than a mosaicable tumor. We've got interconnected cords and strands. We have somewhat of a ribiform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of the cells are round to oval. They're fairly large. These cells have some faint eosinophilic to pale gray cytoplasm, although this cytoplasm is kind of difficult to see. Some of these cells have an evenly dispersed or vesicular chromatin pattern, and other nuclei are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and",
"corrected_text": " If we move to higher power, we can see that we're dealing with an epithelial rather than a mesenchymal tumor. We've got interconnected cords and strands. We have somewhat of a cribriform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of the cells are round to oval. They're fairly large. These cells have some faint eosinophilic to pale gray cytoplasm, although this cytoplasm is kind of difficult to see. Some of these cells have an evenly dispersed or vesicular chromatin pattern, and other nuclei are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'epithelial tumor', 'concept_id': 'C1368683', 'confidence': 0.9999999403953552}, {'entity': 'cords', 'concept_id': 'C0034869', 'confidence': 0.801885187625885}, {'entity': 'strands', 'concept_id': 'C0600383', 'confidence': 0.800572395324707}], [{'entity': 'Cribriform pattern', 'concept_id': 'C1333163', 'confidence': 1.0}, {'entity': 'loose', 'concept_id': 'C0205407', 'confidence': 1.0}, {'entity': 'edematous', 'concept_id': 'C0013604', 'confidence': 1.0}, {'entity': 'vascular stroma', 'concept_id': 'C0005847', 'confidence': 0.8046398758888245}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'cell types', 'concept_id': 'C0007634', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'eosinophilic', 'concept_id': 'C0333930', 'confidence': 1.0}, {'entity': 'pale', 'concept_id': 'C0030232', 'confidence': 1.0}, {'entity': 'gray cytoplasm', 'concept_id': 'C0010834', 'confidence': 0.8177905678749084}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'duct', 'concept_id': 'C0687028', 'confidence': 1.0}, {'entity': 'formation', 'concept_id': 'C0220781', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_31",
"caption_rating": "8"
},
{
"": "1004983",
"caption": "Identification of the cell type responsible for producing protein fibers and ground substance in connective tissue.",
"image_path": "ib991vTA67A_image_d514347b-6cdc-4749-bc63-ac10e3f50b47.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Head and Neck']",
"roi_text": "['scattered little nuclei', 'cell type making protein fibers and ground substance in connective tissue']",
"noisy_text": " So here's, here's, here's this one. So number sixteen, what is this Connective Tissue and tell me the name of the scattered little nuclei, we see the nuclei all throughout here. Most of these nuclei belong to what cell, that cell is making the protein fibers and the ground substance in this Connective Tissue. So what cell type is living in here that's making these protein fibers and the ground substance in this Connective Tissue? That was number sixteen. Here's this one, seeing it again, this one's not quite as clear, you can see the protein fibers here,",
"corrected_text": " So here's, here's, here's this one. So number sixteen, what is this Connective Tissue and tell me the name of the scattered little nuclei, we see the nuclei all throughout here. Most of these nuclei belong to what cell, that cell is making the protein fibers and the ground substance in this Connective Tissue. So what cell type is living in here that's making these protein fibers and the ground substance in this Connective Tissue? That was number sixteen. Here's this one, seeing it again, this one's not quite as clear, you can see the protein fibers here,",
"med_umls_ids": "[[{'entity': 'Identification', 'concept_id': 'C0020792', 'confidence': 1.0}, {'entity': 'cell type', 'concept_id': 'C0007634', 'confidence': 1.0}, {'entity': 'protein fibers', 'concept_id': 'C0000696', 'confidence': 0.7645217180252075}, {'entity': 'ground substance', 'concept_id': 'C1253945', 'confidence': 1.0}, {'entity': 'connective tissue', 'concept_id': 'C0009780', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1152.0",
"id": "test_32",
"caption_rating": "8"
},
{
"": "1006175",
"caption": "Intraductal carcinoma of the prostate itself is not associated with these factors, but rather the invasive cancer next to it.",
"image_path": "iklRyY1nBIE_image_7da9a82d-4e58-4ad6-99ed-e452daa7ec40.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['Presence of high-volume prostate cancer with poorly formed glands and single cells.', 'Intraductal component.']",
"noisy_text": " are associated with extra-postatic extension. They are associated with, which you can see here, they are associated with positive margins. They are associated with lymph node metastasis. It is not the introductal carcinoma of the prostate itself that is associated with those. It's the fact that you have high-volume, high-grade invasive cancer next door. It is the invasive cancer that does all those bad things. The introductal carcinoma itself is introductal. It's just invasive cancer colonizing a duct. So the introductal carcinoma itself doesn't do all those bad things. It is associated with high-grade invasive cancer that does the high tumor volume, extra-postatic extension, positive surgical margins, and lymph node metastasis. And I'll show you a case of that shortly. So if you look at this case, again, high-volume prostate cancer. You can see that a lot of the glands are poorly formed. There are some single cells in there. And once again, you see the introductal component here. You can",
"corrected_text": " are associated with extra-prostatic extension. They are associated with, which you can see here, they are associated with positive margins. They are associated with lymph node metastasis. It is not the intrAductal carcinoma of the prostate itself that is associated with those. It's the fact that you have high-volume, high-grade invasive cancer next door. It is the invasive cancer that does all those bad things. The intrAductal carcinoma itself is intracystic. It's just invasive cancer colonizing a duct. So the intrAductal carcinoma itself doesn't do all those bad things. It is associated with high-grade invasive cancer that does the high tumor volume, extra-prostatic extension, positive surgical margins, and lymph node metastasis. And I'll show you a case of that shortly. So if you look at this case, again, high-volume prostate cancer. You can see that a lot of the glands are poorly formed. There are some single cells in there. And once again, you see the intracystic component here. You can",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'high-volume', 'concept_id': 'C3494218', 'confidence': 0.8583465814590454}, {'entity': 'high-grade invasive cancer', 'concept_id': 'C1512433', 'confidence': 0.6872689723968506}, {'entity': 'associated with', 'concept_id': 'C0332281', 'confidence': 1.0}, {'entity': 'extra-prostatic extension', 'concept_id': 'C1717821', 'confidence': 0.8074824213981628}, {'entity': 'positive margins', 'concept_id': 'C1709603', 'confidence': 1.0}, {'entity': 'lymph node metastasis', 'concept_id': 'C0686619', 'confidence': 1.0}], [{'entity': 'Intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'associated with', 'concept_id': 'C0332281', 'confidence': 1.0}, {'entity': 'factors', 'concept_id': 'C1257900', 'confidence': 0.8623767495155334}, {'entity': 'invasive cancer', 'concept_id': 'C0677898', 'confidence': 1.0}], [{'entity': 'Intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}, {'entity': 'colonizing', 'concept_id': 'C1300196', 'confidence': 0.61208176612854}, {'entity': 'duct', 'concept_id': 'C0687028', 'confidence': 1.0}, {'entity': 'associated with', 'concept_id': 'C0332281', 'confidence': 1.0}, {'entity': 'high-grade invasive cancer', 'concept_id': 'C1512433', 'confidence': 0.6872689723968506}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'outcomes', 'concept_id': 'C1274040', 'confidence': 0.8844040036201477}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_33",
"caption_rating": "7"
},
{
"": "1006536",
"caption": "Superficial perivascular infiltrate present within the dermis.",
"image_path": "8S4LeiO6Bbk_image_24e7ef9f-fdec-4317-a973-ebbc11a14881.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['superficial perivascular infiltrate', 'epidermis', 'basement of the rete ridge pattern', 'basal cell change along the DEJ', 'dyskeratotic cells within the basal layer', 'papillary dermis']",
"noisy_text": " Moving on to slide number eight. Slide number eight is the first of two interface dermatitis that we're going to be looking at. This is a bisected punch biopsy from the trunk or proximal extremity. Get that down and in this specimen we can see that we've got a superficial perivascular infiltrate present within the dermis. We've clearly got evidence of some epidural change here. The epidermis is quite thin, the basement of the Reedy ridge pattern. We have a basket we've cornified layer but as we zoom in we can see that we've got pronounced bacular change along the DEJ, scattered dyskeratotic cells within the basal layer, and within the papillary dermis we have a",
"corrected_text": " Moving on to slide number eight. Slide number eight is the first of two interface dermatitis that we're going to be looking at. This is a bisected punch biopsy from the trunk or proximal extremity. Get that down and in this specimen we can see that we've got a superficial perivascular infiltrate present within the dermis. We've clearly got evidence of some epidural change here. The epidermis is quite thin, the basement of the rete ridge pattern. We have a basket we've cornified layer but as we zoom in we can see that we've got pronounced basal cell change along the DEJ, scattered dyskeratotic cells within the basal layer, and within the papillary dermis we have a",
"med_umls_ids": "[[{'entity': 'punch biopsy', 'concept_id': 'C0182557', 'confidence': 1.0}, {'entity': 'trunk', 'concept_id': 'C0225442', 'confidence': 0.9999999403953552}, {'entity': 'proximal extremity', 'concept_id': 'C0015385', 'confidence': 0.745482325553894}], [{'entity': 'Superficial', 'concept_id': 'C0205124', 'confidence': 1.0}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}], [{'entity': 'Evidence', 'concept_id': 'C3887511', 'confidence': 1.0}, {'entity': 'epidural change', 'concept_id': 'C0228134', 'confidence': 0.7621071338653564}], [{'entity': 'Thin epidermis', 'concept_id': 'C4231265', 'confidence': 1.0}, {'entity': 'basement', 'concept_id': 'C0085872', 'confidence': 0.772655725479126}, {'entity': 'rete', 'concept_id': 'C0010306', 'confidence': 0.7033917903900146}, {'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}], [{'entity': 'basal cell', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'DEJ', 'concept_id': 'C0385794', 'confidence': 0.5962325930595398}], [{'entity': 'Scattered', 'concept_id': 'C0439742', 'confidence': 1.0}, {'entity': 'dyskeratotic cells', 'concept_id': 'C1512098', 'confidence': 0.8970272541046143}, {'entity': 'basal layer', 'concept_id': 'C0221925', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_34",
"caption_rating": "9"
},
{
"": "1005487",
"caption": "Immunohistochemical stains will be positive for PSA and PSAP.",
"image_path": "iklRyY1nBIE_image_482715a2-ddb7-4de9-b13d-4ac9747c562d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['Prostatic adenocarcinoma with mucinous features.']",
"noisy_text": " Yeah, so this is a nice case of prosthetic adenocarcinoma with misnose features. As some of you may be aware, there's strict criteria for that. If it's less than 25% involvement, we say misnose features. If it's greater than 25% or more, then you can actually use the term misnose adenocarcinoma with the prostate. The reason why I'm showing you this case is because here you don't see the tumor is just doing its own thing and the stroma is doing its own thing. There's no desmoplastic stromal response. There's no fluid host inflammatory response. So this is a different entity. In the past, these tumors were actually confused with one another. They thought it was the same thing decades ago. That's why in the past, misnose adenocarcinoma with the prostate were thought to be very aggressive tumors. But now we've kind of dissected these two separate entities. Of course, back then, 30 years ago, we didn't have the benefit of immunohistochemical stains. So what you're looking at right now will obviously be positive for PSA and PSAP. The original case I",
"corrected_text": " Yeah, so this is a nice case of prosthetic adenocarcinoma with mucinous features. As some of you may be aware, there's strict criteria for that. If it's less than 25% involvement, we say mucinous features. If it's greater than 25% or more, then you can actually use the term mucinous adenocarcinoma with the prostate. The reason why I'm showing you this case is because here you don't see the tumor is just doing its own thing and the stroma is doing its own thing. There's no desmoplastic stromal response. There's no fluid host inflammatory response. So this is a different entity. In the past, these tumors were actually confused with one another. They thought it was the same thing decades ago. That's why in the past, mucinous adenocarcinoma with the prostate were thought to be very aggressive tumors. But now we've kind of dissected these two separate entities. Of course, back then, 30 years ago, we didn't have the benefit of immunohistochemical stains. So what you're looking at right now will obviously be positive for PSA and PSAP. The original case I",
"med_umls_ids": "[[{'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'prostatic adenocarcinoma', 'concept_id': 'C0007112', 'confidence': 1.0}, {'entity': 'mucinous features', 'concept_id': 'C1513712', 'confidence': 0.7035756707191467}, {'entity': 'criteria', 'concept_id': 'C0243161', 'confidence': 0.9999998807907104}, {'entity': 'involvement', 'concept_id': 'C1314939', 'confidence': 1.0}], [{'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'desmoplastic reaction', 'concept_id': 'C1511789', 'confidence': 1.0}, {'entity': 'fluid', 'concept_id': 'C0005889', 'confidence': 1.0}, {'entity': 'host', 'concept_id': 'C1167395', 'confidence': 0.9999999403953552}, {'entity': 'inflammatory response', 'concept_id': 'C1155266', 'confidence': 1.0}, {'entity': 'entity', 'concept_id': 'C1551338', 'confidence': 1.0}], [{'entity': 'Mucinous adenocarcinoma', 'concept_id': 'C0007130', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'aggressive', 'concept_id': 'C0001807', 'confidence': 1.0}], [{'entity': 'Immunohistochemical stains', 'concept_id': 'C4317108', 'confidence': 0.9999999403953552}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'PSA', 'concept_id': 'C0138741', 'confidence': 1.0}, {'entity': 'PSAP', 'concept_id': 'C1418975', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_35",
"caption_rating": "8"
},
{
"": "1006188",
"caption": "A small subset of these tumors actually occur de novo within a previously benign gland.",
"image_path": "iklRyY1nBIE_image_f98d30b9-5304-4210-b9f8-92fc429a8533.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['basal cells at the periphery', 'enlarged nuclei', 'intraductal carcinoma of the prostate', 'adjacent invasive tumor', 'previously benign gland', 'basal cells at the periphery', 'enlarged nuclei', 'intraductal carcinoma of the prostate', 'adjacent invasive tumor', 'previously benign gland']",
"noisy_text": " Let me show you what the cocktail looks like. Again, this is the pin three, or some call it pin four. You have the P63, you have the hemoglobin cytokeratin, and then you have the racemase, which is the pink chromogen. And as you can see, as I demonstrated on the H&E, basal cells are indeed present. This is too much for high-grade pin. This is basically what is called a solid cribriform kind of pattern, in which over 50% of the lumen is filled by tumor cells. So this is way too much for high-grade pin. But it's not invasive, because you have basal cells at the periphery. And the nuclei are enlarged. These nuclei are about six times the size of normal prostate nuclei. So this case meets the criteria for introductal carcinoma of the prostate. There is an invasive component, which you can see is negative for basal cell markers. But you have the introductal component. And this is a very interesting entity. The vast majority of cases, and I'll show you the corresponding radical prostatectomy specimens in a second, but the vast majority of these so-called introductal carcinoma of the prostate is due to invasion, colonization by adjacent invasive tumor. And it usually occurs in patients that have high-volume tumors. When I show you the corresponding radical prostatectomies, you'll see what I'm talking about. You usually don't have this in patients in their radicals that have 5% prostate cancer or 10% prostate cancer. It's usually patients that have extensive prostate cancer involvement, and the invasive glands basically have nowhere else to go but to colonize adjacent benign glands. And I'll demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues,",
"corrected_text": " Let me show you what the cocktail looks like. Again, this is the pin three, or some call it pin four. You have the P63, you have the hemoglobin cytokeratin, and then you have the racemase, which is the AMACR. And as you can see, as I demonstrated on the H&E, basal cells are indeed present. This is too much for high-grade pin. This is basically what is called a solid cribriform kind of pattern, in which over 50% of the lumen is filled by tumor cells. So this is way too much for high-grade pin. But it's not invasive, because you have basal cells at the periphery. And the nuclei are enlarged. These nuclei are about six times the size of normal prostate nuclei. So this case meets the criteria for intraductal carcinoma of the prostate. There is an invasive component, which you can see is negative for basal cell markers. But you have the intraductal component. And this is a very interesting entity. The vast majority of cases, and I'll show you the corresponding radical prostatectomy specimens in a second, but the vast majority of these so-called intraductal carcinoma of the prostate is due to invasion, colonization by adjacent invasive tumor. And it usually occurs in patients that have high-volume tumors. When I show you the corresponding radical prostatectomies, you'll see what I'm talking about. You usually don't have this in patients in their radicals that have 5% prostate cancer or 10% prostate cancer. It's usually patients that have extensive prostate cancer involvement, and the invasive glands basically have nowhere else to go but to colonize adjacent benign glands. And I'demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues,",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'cocktail', 'concept_id': 'C0678420', 'confidence': 1.0}, {'entity': 'markers', 'concept_id': 'C0181734', 'confidence': 0.890313982963562}, {'entity': 'intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate diagnosis', 'concept_id': 'C0011900', 'confidence': 0.7927443981170654}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'basal cells', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}], [{'entity': 'Enlarged nuclei', 'concept_id': 'C4013177', 'confidence': 0.7774685621261597}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'normal', 'concept_id': 'C0205307', 'confidence': 1.0}], [{'entity': 'Intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'invasion', 'concept_id': 'C1269955', 'confidence': 1.0}, {'entity': 'colonization', 'concept_id': 'C4289767', 'confidence': 1.0}, {'entity': 'adjacent', 'concept_id': 'C0205117', 'confidence': 1.0}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}], [{'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'benign gland', 'concept_id': 'C0205183', 'confidence': 0.7986565828323364}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_36",
"caption_rating": "8"
},
{
"": "1004515",
"caption": "Stratification has started and mucin is less, but not lost.",
"image_path": "r7OA0Trj5hQ_image_fdda247c-39b6-4e57-bef4-ca0954805df7.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " that is pathologic in this biopsy. And there is mitosis and apoptosis. Remember, these four criteria for dysplasia. See again here, stratification has started. But you see, mucin is less. It is, I won't say lost. It is less. And this stratified nuclei reach the middle third. They are not touching the upper top of the apical membrane. They are reaching the middle third predominantly. Okay, that is one important point. And other one is, look at this nuclei. They are all traveling in one direction. So the polarity is maintained. Okay, so those two points are very important. And the third one",
"corrected_text": " that is pathologic in this biopsy. And there is mitosis and apoptosis. Remember, these four criteria for dysplasia. See again here, stratification has started. But you see, mucin is less. It is, I won't say lost. It is less. And this stratified nuclei reach the middle third. They are not touching the upper top of the apical membrane. They are reaching the middle third predominantly. Okay, that is one important point. And other one is, look at this nuclei. They are all traveling in one direction. So the polarity is maintained. Okay, so those two points are very important. And the third one",
"med_umls_ids": "[[{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'pathologic', 'concept_id': 'C1521733', 'confidence': 1.0}, {'entity': 'mitosis', 'concept_id': 'C0026255', 'confidence': 0.9999998807907104}, {'entity': 'apoptosis', 'concept_id': 'C0162638', 'confidence': 1.0}], [{'entity': 'Stratification', 'concept_id': 'C1514983', 'confidence': 1.0}, {'entity': 'started', 'concept_id': 'C1272689', 'confidence': 0.9999999403953552}, {'entity': 'mucin', 'concept_id': 'C0026682', 'confidence': 1.0}], [{'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'middle', 'concept_id': 'C0227972', 'confidence': 1.0}, {'entity': 'polarity', 'concept_id': 'C0596963', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_37",
"caption_rating": "8"
},
{
"": "1008010",
"caption": "Presence of collagen balls surrounded by spindle-shaped cells.",
"image_path": "8S4LeiO6Bbk_image_7825d703-9cc5-4cb1-85b8-c798c8e0ebd0.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['spindle-shaped cells']",
"noisy_text": " these collagen balls that are being surrounded by cells that have a somewhat spindled shape. The nuclei are spindled over our fusiform and they're kind of wrapping around these collagen bundles. In this same area, we can begin to see some lipophagia. So we see these large histiocytes containing lipid. Some of them are multi-nucleated and some of these are actually ringed siderophages. So we see large multi-nucleated histiocytes with a ring of nuclei and they contain not only lipid vacuoles but hemocentaurant. And these are particularly common in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes",
"corrected_text": " these collagen balls that are being surrounded by cells that have a somewhat spindle-shaped. The nuclei are spindle-shaped over our fusiform and they're kind of wrapping around these collagen bundles. In this same area, we can begin to see some lipophagic. So we see these large histiocytes containing lipid. Some of them are multi-nucleated and some of these are actually ringed siderophages. So we see large multinucleated histiocytes with a ring of nuclei and they contain not only lipid vacuoles but hemosiderin. And these are particularly common in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'collagen balls', 'concept_id': 'C0009325', 'confidence': 0.7217866778373718}, {'entity': 'surrounded', 'concept_id': 'C1282914', 'confidence': 1.0}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}], [{'entity': 'Lipophagic cells', 'concept_id': 'C0007584', 'confidence': 0.5962335467338562}, {'entity': 'lipid vacuoles', 'concept_id': 'C1179126', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'ringed', 'concept_id': 'C0325501', 'confidence': 0.77345871925354}, {'entity': 'siderophages', 'concept_id': 'C1136253', 'confidence': 0.7251443266868591}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_38",
"caption_rating": "8"
},
{
"": "1009245",
"caption": "The biopsy from the urethra shows urethritis cystica et glandularis, with dissecting pools of mucin that do not necessarily indicate malignancy. Goblet cell formation is visible, indicating the initial stages of mucinous adenocarcinoma.",
"image_path": "iklRyY1nBIE_image_38153e72-4994-4318-a005-d3d7bb8e8c45.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['Urethritis cystica et glandularis', 'Goblet cell formation', 'Urethritis cystica et glandularis', 'Goblet cell formation']",
"noisy_text": " So this was a biopsy from the urethra. And all you can see here is urethritis cystica et glandularis. They're dissecting pools of mucin, but that doesn't always mean there's a malignant process going on. So that's something else one needs to be careful about. There are some areas here that are very concerning. But the reason why I'm showing you this slide is just to show you the overlying urethritis cystic ed glandularis intestinal type. You can actually see some goblet cell formation there. So that's how it starts. And then it progresses to this, where you're not just seeing the surface urethelium involved by this misnose adenocarcinoma, but it's actually beginning to invade the subepithelial connective tissue. It's beginning",
"corrected_text": " So this was a biopsy from the urethra. And all you can see here is urethritis cystica et glandularis. They're dissecting pools of mucin, but that doesn't always mean there's a malignant process going on. So that's something else one needs to be careful about. There are some areas here that are very concerning. But the reason why I'm showing you this slide is just to show you the overlying urethritis cystic ed glandularis intestinal type. You can actually see some goblet cell formation there. So that's how it starts. And then it progresses to this, where you're not just seeing the surface urothelium involved by this mucinous adenocarcinoma, but it's actually beginning to invade the lamina propria. It's beginning",
"med_umls_ids": "[[{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'urethra', 'concept_id': 'C0041967', 'confidence': 1.0}, {'entity': 'urethritis cystica', 'concept_id': 'C3272656', 'confidence': 0.9999998807907104}, {'entity': 'glandularis', 'concept_id': 'C1231964', 'confidence': 0.8643958568572998}, {'entity': 'dissecting pools', 'concept_id': 'C0205239', 'confidence': 0.6663767695426941}, {'entity': 'mucin', 'concept_id': 'C0026682', 'confidence': 1.0}, {'entity': 'malignancy', 'concept_id': 'C0006826', 'confidence': 1.0}, {'entity': 'Goblet', 'concept_id': 'C0506994', 'confidence': 0.8473865389823914}, {'entity': 'cell formation', 'concept_id': 'C2936218', 'confidence': 0.9225678443908691}, {'entity': 'visible', 'concept_id': 'C0205379', 'confidence': 0.9999998807907104}, {'entity': 'stages', 'concept_id': 'C1306673', 'confidence': 0.9999999403953552}, {'entity': 'mucinous adenocarcinoma', 'concept_id': 'C0007130', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_39",
"caption_rating": "8"
},
{
"": "1008427",
"caption": "Identification of squamous epithelium and gastric cardiac type of epithelium at the gastroesophageal junction.",
"image_path": "r7OA0Trj5hQ_image_1fdf87d9-3b35-436e-a6d3-626e2677646a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Gastroesophageal junction with irregularly sized and shaped glands and variation in distribution.']",
"noisy_text": " metaplasia or dysplasia, either low-grade or high-grade. So this is a squamous epithelium. This is a gastric cardiac type of epithelium. So this is a gastroesophageal junction. Here you can see nice bifitting. And see the glands are not uniformly distributed. Variation in size. Some glands are small, some glands are large. And these glands are not branching normally, but you can see a nice bifitting. So these are all features of chronicity. Irregular size, shape, distribution means chronicity. Please remember, presence of lymphocytes and plasma cells is not a",
"corrected_text": " metaplasia or dysplasia, either low-grade or high-grade. So this is a squamous epithelium. This is a gastric cardiac type of epithelium. So this is a gastroesophageal junction. Here you can see nice bifitting. And see the glands are not uniformly distributed. Variation in size. Some glands are small, some glands are large. And these glands are not branching normally, but you can see a nice bifitting. So these are all features of chronicity. Irregular size, shape, distribution means chronicity. Please remember, presence of lymphocytes and plasma cells is not a",
"med_umls_ids": "[[{'entity': 'Identification', 'concept_id': 'C0020792', 'confidence': 1.0}, {'entity': 'squamous epithelium', 'concept_id': 'C0221909', 'confidence': 1.0}, {'entity': 'gastric cardiac type', 'concept_id': 'C0524600', 'confidence': 0.7429378628730774}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'gastroesophageal junction', 'concept_id': 'C0014871', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'irregularly', 'concept_id': 'C0425589', 'confidence': 0.905201256275177}, {'entity': 'sized', 'concept_id': 'C0600244', 'confidence': 0.8308623433113098}, {'entity': 'shaped glands', 'concept_id': 'C0332479', 'confidence': 0.7275685667991638}, {'entity': 'variation', 'concept_id': 'C0205419', 'confidence': 1.0}, {'entity': 'distribution', 'concept_id': 'C0037775', 'confidence': 1.0}, {'entity': 'chronicity', 'concept_id': 'C0547045', 'confidence': 1.0}], [{'entity': 'Importance', 'concept_id': 'C4086513', 'confidence': 0.96006178855896}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_40",
"caption_rating": "9"
},
{
"": "1004616",
"caption": "Involvement around damaged nerves is a common feature of sarcoid granulomatous inflammation.",
"image_path": "udoW6VSqsm4_image_e51a876a-6b32-4cb6-8b7b-25b3f8e6b479.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['sarcoid granulomatous inflammation', 'involvement around nerves']",
"noisy_text": " That's the tuberculoid. Yeah, good. The tuberculoid form of leprosy gives you sarcoidal granulomatous inflammation. It's elongated. Very good. That's exactly right. What else can give you sarcoidal granulomatous inflammation? Can I ask a quick question about the sarcoid with the two... The nansins? So, I had a case, I saw a case that looked kind of horizontal, but it was sarcoid. And so, what other ways can you tell? Sometimes it can be difficult, but usually you're going to see involvement around nerves damaged nerves. You're about to get sarcoidal granulomatous inflammation. They always have very high risk inflammatory reactions. They just wipe out the nerves. So, that's helpful. Wasn't",
"corrected_text": " That's the tuberculoid. Yeah, good. The tuberculoid form of leprosy gives you sarcoidal granulomatous inflammation. It's elongated. Very good. That's exactly right. What else can give you sarcoidal granulomatous inflammation? Can I ask a quick question about the sarcoid with the two... The sarcoidosis? So, I had a case, I saw a case that looked kind of horizontal, but it was sarcoid. And so, what other ways can you tell? Sometimes it can be difficult, but usually you're going to see involvement around nerves damaged nerves. You're about to get sarcoidal granulomatous inflammation. They always have very high risk inflammatory reactions. They just wipe out the nerves. So, that's helpful. Wasn't",
"med_umls_ids": "[[{'entity': 'Tuberculoid', 'concept_id': 'C0544783', 'confidence': 0.8459237217903137}, {'entity': 'leprosy', 'concept_id': 'C0023343', 'confidence': 1.0}, {'entity': 'sarcoid', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'granulomatous inflammation', 'concept_id': 'C0553697', 'confidence': 1.0}], [{'entity': 'Involvement', 'concept_id': 'C1314939', 'confidence': 1.0}, {'entity': 'damaged nerves', 'concept_id': 'C3887709', 'confidence': 0.8087002038955688}, {'entity': 'sarcoid', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'granulomatous inflammation', 'concept_id': 'C0553697', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_41",
"caption_rating": "8"
},
{
"": "1006266",
"caption": "Proliferation of thin-walled vascular channels of variable size towards the fetal surface of the placenta.",
"image_path": "PJX3uZ7fRn4_image_6e06942c-9cdd-4403-a87b-fb8b5258284b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gynecologic', 'Soft tissue', 'Hematopathology']",
"roi_text": "['vascular channels', 'chorionic villi', 'calcification', 'vascular channels', 'chorionic villi', 'calcification']",
"noisy_text": " This is a section from placenta which shows a large irregular area with proliferation of thin walled vascular channels of variable size towards the fetal surface of placenta. Smaller chorionic villi can be seen towards the maternal site. Higher magnification of the same showing large vascular channels in the chorion filled with blood. Still higher magnification showing intercommunicating slit-like vascular spaces in the mass. Focal area of calcification can be seen in the tumor. Still another area",
"corrected_text": " This is a section from placenta which shows a large irregular area with proliferation of thin walled vascular channels of variable size towards the fetal surface of placenta. smaller chorionic villi are not incorrect can be seen towards the maternal site. Higher magnification of the same showing large vascular channels in the chorion filled with blood. Still higher magnification showing intercommunicating slit-like vascular spaces in the mass. Focal area of calcification can be seen in the tumor. Still another area",
"med_umls_ids": "[[{'entity': 'Proliferation', 'concept_id': 'C0334094', 'confidence': 1.0}, {'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}, {'entity': 'variable size', 'concept_id': 'C1866144', 'confidence': 0.8559831976890564}, {'entity': 'fetal', 'concept_id': 'C0015965', 'confidence': 1.0}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'placenta', 'concept_id': 'C0032043', 'confidence': 1.0}], [{'entity': 'chorionic villi', 'concept_id': 'C0008508', 'confidence': 1.0}, {'entity': 'maternal site', 'concept_id': 'C0026591', 'confidence': 0.7640593647956848}], [{'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}, {'entity': 'chorion', 'concept_id': 'C0008503', 'confidence': 0.9999998807907104}, {'entity': 'blood', 'concept_id': 'C0005767', 'confidence': 1.0}], [{'entity': 'Intercommunicating', 'concept_id': 'C0205196', 'confidence': 0.8271207213401794}, {'entity': 'vascular spaces', 'concept_id': 'C0225983', 'confidence': 0.819495439529419}, {'entity': 'mass', 'concept_id': 'C0577559', 'confidence': 1.0}], [{'entity': 'Focal area', 'concept_id': 'C0205234', 'confidence': 0.7634891271591187}, {'entity': 'calcification', 'concept_id': 'C0006660', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_42",
"caption_rating": "9"
},
{
"": "1005754",
"caption": "Lamina propria on the right is typically busier with eosinophils, lymphocytes, and plasma cells.",
"image_path": "sDFjOtMAYrk_image_0372a472-d9ea-41fa-aabd-99bb51529283.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['lamina propria', 'inflammatory cells', 'eosinophils', 'lymphocytes', 'plasma cells', 'basement membrane', 'lamina propria', 'inflammatory cells', 'eosinophils', 'lymphocytes', 'plasma cells', 'basement membrane']",
"noisy_text": " segment and shows a lamina propria pretty devoid of... You see a couple of inflammatory cells here and there, but not really a lot in the way of lymphocytes, plasma cells, and actually eos are rare. But when you get biopsies, and I'm sorry I didn't bring one from... That was on the left. If you used to have something from the right, your lamina propria is typically busier, and I allow for quite a few eosinophils, lymphocytes, and plasma cells. The other thing that you want to keep in mind is... Let me just go back to the H and E for a second. The basement membrane, I will",
"corrected_text": " segment and shows a lamina propria pretty devoid of... You see a couple of inflammatory cells here and there, but not really a lot in the way of lymphocytes, plasma cells, and actually eos are rare. But when you get biopsies, and I'm sorry I didn't bring one from... That was on the left. If you used to have something from the right, your lamina propria is typically busier, and I allow for quite a few eosinophils, lymphocytes, and plasma cells. The other thing that you want to keep in mind is... Let me just go back to the H and E for a second. The basement membrane, I will",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'segment', 'concept_id': 'C0441635', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'inflammatory cells', 'concept_id': 'C0440752', 'confidence': 1.0}], [{'entity': 'Lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'right', 'concept_id': 'C0205090', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_43",
"caption_rating": "8"
},
{
"": "1006201",
"caption": "Urothelial metaplasia can occur simultaneously with basal cell hyperplasia.",
"image_path": "iklRyY1nBIE_image_d7c2bb0e-8d25-4b93-96f4-a06df852db5d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " This is just basal cell hyperplasia. Sometimes you can have urothelial metaplasia also occurring simultaneously. All right, so the next case is case 7. Case 7 is a 69-year-old gentleman with hematuria and mycosuria. So this is the first time we are hearing that word, mycosuria. So we've had elevated PSA levels. We've had positive DREs. We've had hematuria. But this is the first patient that has mycosuria. And that's of some significance, which you'll see shortly. So let's take a look at this case. Again, this doesn't look like anything I've shown",
"corrected_text": " This is just basal cell hyperplasia. Sometimes you can have urothelial metaplasia also occurring simultaneously. All right, so the next case is case 7. Case 7 is a 69-year-old gentleman with hematuria and mycosuria. So this is the first time we are hearing that word, mycosuria. So we've had elevated PSA levels. We've had positive DREs. We've had hematuria. But this is the first patient that has mycosuria. And that's of some significance, which you'll see shortly. So let's take a look at this case. Again, this doesn't look like anything I've shown",
"med_umls_ids": "[[{'entity': 'Basal cell', 'concept_id': 'C0596155', 'confidence': 1.0}], [{'entity': 'Urothelial metaplasia', 'concept_id': 'C0334028', 'confidence': 0.8153573870658875}, {'entity': 'simultaneously', 'concept_id': 'C0521115', 'confidence': 1.0}, {'entity': 'basal cell hyperplasia', 'concept_id': 'C0333990', 'confidence': 1.0}], [{'entity': 'Mycosuria', 'concept_id': 'C0017979', 'confidence': 0.7108948826789856}, {'entity': 'male', 'concept_id': 'C0086582', 'confidence': 1.0}, {'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'hematuria', 'concept_id': 'C0018965', 'confidence': 1.0}, {'entity': 'elevated', 'concept_id': 'C0205250', 'confidence': 0.9999999403953552}, {'entity': 'PSA', 'concept_id': 'C0138741', 'confidence': 1.0}, {'entity': 'levels', 'concept_id': 'C0441889', 'confidence': 1.0}], [{'entity': 'Mycosuria', 'concept_id': 'C0017979', 'confidence': 0.7108948826789856}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_44",
"caption_rating": "8"
},
{
"": "1006017",
"caption": "No stain has been found to be helpful in diagnosing sclerosing epithelial neoplasms.",
"image_path": "LlPaENuqzVQ_image_2beb252a-0e73-4aee-92e8-acad841e9e79.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['Lesion dissecting throughout the dermis', 'No nerve involvement observed', 'Sclerosing epithelial neoplasms', 'Deep biopsy necessary for definitive diagnosis']",
"noisy_text": " So this thing is kind of dissecting diffusely throughout the dermis here. I don't see any nerve involvement in this case but it's very common to get neurotropism and microcystic anexal carcinoma. So I'm not gonna belabor the differential diagnosis of the sclerosing epithelial neoplasms but you need to know that. And you need to know that you need to take a good deep biopsy in order to make a definitive diagnosis or you won't get a definitive diagnosis. And there's no stain that helps. Everybody says, oh, you can do a T63 or this and the other, looking for Merkel cells or CK20. I've never found any of these things to be helpful. And the other differential that sometimes comes up is the",
"corrected_text": " So this thing is kind of dissecting diffusely throughout the dermis here. I don't see any nerve involvement in this case but it's very common to get neurotropism and microcystic adnexal carcinoma. So I'm not gonna belabor the differential diagnosis of the sclerosing epithelial neoplasms but you need to know that. And you need to know that you need to take a good deep biopsy in order to make a definitive diagnosis or you won't get a definitive diagnosis. And there's no stain that helps. Everybody says, oh, you can do a T63 or this and the other, looking for Merkel cells or CK20. I've never found any of these things to be helpful. And the other differential that sometimes comes up is the",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'diffusely', 'concept_id': 'C0205219', 'confidence': 0.8011853098869324}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}], [{'entity': 'Neurotropism', 'concept_id': 'C1518304', 'confidence': 1.0}, {'entity': 'microcystic adnexal carcinoma', 'concept_id': 'C0346027', 'confidence': 1.0}, {'entity': 'nerves', 'concept_id': 'C0027740', 'confidence': 1.0}], [{'entity': 'deep biopsy', 'concept_id': 'C0185285', 'confidence': 0.8188310265541077}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'sclerosing', 'concept_id': 'C0036426', 'confidence': 0.833010733127594}, {'entity': 'epithelial neoplasms', 'concept_id': 'C1368683', 'confidence': 0.9999999403953552}], [{'entity': 'No stain', 'concept_id': 'C0038128', 'confidence': 0.8399802446365356}, {'entity': 'diagnosing', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'sclerosing', 'concept_id': 'C0036426', 'confidence': 0.833010733127594}, {'entity': 'epithelial neoplasms', 'concept_id': 'C1368683', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_45",
"caption_rating": "8"
},
{
"": "1006246",
"caption": "Presence of plasma cells within the infiltrate can help distinguish between the condition and Kaposi's sarcoma. Negative HHV8 stain also rules out Kaposi's sarcoma. Diagnosis in this case is targetoid hemosiderotic hemangioma, which commonly appears on the trunk or extremities and is characterized by a central dark blue or purple papule surrounded by a zone of power and then an eccentric ring. Lesions stain frequently with CD34 and are strongly positive for D240, indicating lymphatic origin. The tumor is biphasic with dilated vascular channels and papillary projections.",
"image_path": "8S4LeiO6Bbk_image_bd4e7bbb-54de-40c2-b167-ac9b83a64d34.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['plasma cells within the infiltrate', 'central dark blue or purple papule', 'eccentric ring', 'papillary projections', 'plump endothelial']",
"noisy_text": " plasma cells within the infiltrate. And plasma cells within the infiltrate can be very useful in discriminating between this condition and Kaposi's sarcoma. In this particular case, also the HHV8 stain was a negative, which would be positive in Kaposi's sarcoma. So the diagnosis in this case was a targetoid hemocidiotic hemangioma, sometimes known as a hobnail hemangioma. Frequently has a characteristic clinical appearance, occurs commonly on the trunk or extremities. It is characterized usually by a central dark blue or purple papule surrounded by a zone of power and then an ecomotic ring, which will slowly risk halt. These lesions will stain, frequently with CD34, but also are strongly positive for D240. So they probably are of lymphatic origin rather than vascular origin. What one looks for is a biphasic vascular tumor with this central area characterized by these dilated vascular channels. Let's look at the bottom piece, which frequently do contain these papillary projections, which protrude into the lumina, these plump endothelial cells, and",
"corrected_text": " plasma cells within the infiltrate. And plasma cells within the infiltrate can be very useful in discriminating between this condition and Kaposi's sarcoma. In this particular case, also the HHV8 stain was a negative, which would be positive in Kaposi's sarcoma. So the diagnosis in this case was a targetoid hemosiderotic hemangioma, sometimes known as a hobnail hemangioma. Frequently has a characteristic clinical appearance, occurs commonly on the trunk or extremities. It is characterized usually by a central dark blue or purple papule surrounded by a zone of power and then an eccentric ring, which will slowly risk halt. These lesions will stain, frequently with CD34, but also are strongly positive for D240. So they probably are of lymphatic origin rather than vascular origin. What one looks for is a biphasic vascular tumor with this central area characterized by these dilated vascular channels. Let's look at the bottom piece, which frequently do contain these papillary projections, which protrude into the lumina, these plump endothelial cells, and",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': \"Kaposi's sarcoma\", 'concept_id': 'C0036220', 'confidence': 1.0}, {'entity': 'Negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'rules', 'concept_id': 'C0870077', 'confidence': 1.0}, {'entity': \"Kaposi's sarcoma\", 'concept_id': 'C0036220', 'confidence': 1.0}, {'entity': 'Diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'targetoid hemosiderotic hemangioma', 'concept_id': 'C0346076', 'confidence': 0.9999999403953552}, {'entity': 'trunk', 'concept_id': 'C0225442', 'confidence': 0.9999999403953552}, {'entity': 'extremities', 'concept_id': 'C0015385', 'confidence': 1.0}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'central dark blue', 'concept_id': 'C1958010', 'confidence': 0.6706290245056152}, {'entity': 'purple papule', 'concept_id': 'C0439542', 'confidence': 0.759922981262207}, {'entity': 'surrounded', 'concept_id': 'C1282914', 'confidence': 1.0}, {'entity': 'zone', 'concept_id': 'C1710706', 'confidence': 1.0}, {'entity': 'power', 'concept_id': 'C0032863', 'confidence': 1.0}, {'entity': 'eccentric ring', 'concept_id': 'C0439740', 'confidence': 0.9041137099266052}, {'entity': 'Lesions', 'concept_id': 'C0221198', 'confidence': 1.0}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'CD34', 'concept_id': 'C0054953', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'D240', 'concept_id': 'C3766973', 'confidence': 0.5323090553283691}, {'entity': 'lymphatic origin', 'concept_id': 'C0229889', 'confidence': 0.7706887125968933}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'biphasic', 'concept_id': 'C0205184', 'confidence': 1.0}, {'entity': 'dilated', 'concept_id': 'C0700124', 'confidence': 0.9999999403953552}, {'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}, {'entity': 'papillary projections', 'concept_id': 'C0016538', 'confidence': 0.7451471090316772}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_46",
"caption_rating": "9"
},
{
"": "1004273",
"caption": "Description of pancreatic acinar metaplasia in the stomach and small intestine.",
"image_path": "r7OA0Trj5hQ_image_a8ef8a8e-635f-4884-82b5-1f2a594f5e1e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['acinar structures resembling pancreas', 'pancreatic acinar-like structures in the GIT', 'acinar structures resembling pancreas', 'pancreatic acinar-like structures in the GIT']",
"noisy_text": " Sometimes the stomach can show acinar structures resembling pancreas. Then it is known as pancreatic acinar metaplasia. This can also happen in the small intestine. There, when you do staining for amylase or trypsin, it will be positive, but on H&E itself, you can see pancreatic acinar-like structures in the GIT. Then it will become pancreatic acinar metaplasia. Here is the best example of atrophy. Again, unfortunately, there is no defined number of glands to be seen because this is age-dependentation, size-dependentation, race-dependent. So",
"corrected_text": " Sometimes the stomach can show acinar structures resembling pancreas. Then it is known as pancreatic acinar metaplasia. This can also happen in the small intestine. There, when you do staining for amylase or trypsin, it will be positive, but on H&E itself, you can see pancreatic acinar-like structures in the GIT. Then it will become pancreatic acinar metaplasia. Here is the best example of atrophy. Again, unfortunately, there is no defined number of glands to be seen because this is age-dependentation, size-dependentation, race-dependent. So",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'pancreatic acinar metaplasia', 'concept_id': 'C4021967', 'confidence': 0.7844848036766052}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'small intestine', 'concept_id': 'C0021852', 'confidence': 1.0}], [{'entity': 'Staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'amylase', 'concept_id': 'C0002712', 'confidence': 1.0}, {'entity': 'trypsin', 'concept_id': 'C0041236', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'intestine', 'concept_id': 'C0021853', 'confidence': 1.0}], [{'entity': 'atrophy', 'concept_id': 'C0333641', 'confidence': 1.0}, {'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'age', 'concept_id': 'C0001779', 'confidence': 1.0}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'dependence', 'concept_id': 'C0011546', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_47",
"caption_rating": "8"
},
{
"": "1004373",
"caption": "Chronic vasculitis can end up forming fibrotic nodules.",
"image_path": "udoW6VSqsm4_image_4616f6ad-a0aa-43a0-a0ed-7b746818cd8e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " You notice this is on acral skin. There are often nodules in that area, and they can start off as palpable purpura in some cases. So, it's like, you know, regular leukocytoplastic vasculitis that can end up with these nodular lesions. Next slide. What is the histologic identical twin of this process? The granulomyphial. Yes, excellent. Granulomyphial looks very, very similar to this on the microscope. Obviously, clinically, it's not like this. It's on the face. It's on the pseudolymphoma. Next slide. So, this is a type of chronic vasculitis that ends up forming these fibrotic nodules. It's an interesting condition, and it is thought to be associated with other conditions. So, you want to make sure that you don't just, next case. A lot of times, these things can give you cholesterol clefts. One of the old names for this years ago used to be extracellular cholesterolosis, and it would give you these, all these neutrophils would gradually degranulate, if you will. The neutrophil products would have lipid in them, and you'd get these cholesterol clefts that would look kind of yellowish. Now, what are a couple other clinical diseases where you can see nodules around joints? You know, like, gout, RA, OE. Good. Gout, RA. There's",
"corrected_text": " You notice this is on acral skin. There are often nodules in that area, and they can start off as palpable purpura in some cases. So, it's like, you know, leukocytoclastic vasculitis that can end up with these nodular lesions. Next slide. What is the histologic identical twin of this process? The granuloma faciale. Yes, excellent. granuloma faciale looks very, very similar to this on the microscope. Obviously, clinically, it's not like this. It's on the face. It's on the pseudolymphoma. Next slide. So, this is a type of chronic vasculitis that ends up forming these fibrotic nodules. It's an interesting condition, and it is thought to be associated with other conditions. So, you want to make sure that you don't just, next case. A lot of times, these things can give you cholesterol clefts. One of the old names for this years ago used to be extracellular cholesterolosis, and it would give you these, all these neutrophils would gradually degranulate, if you will. The neutrophil products would have lipid in them, and you'd get these cholesterol clefts that would look kind of yellowish. Now, what are a couple other clinical diseases where you can see nodules around joints? You know, like, gout, RA, OE. Good. Gout, RA. There's",
"med_umls_ids": "[[{'entity': 'Nodules', 'concept_id': 'C0028259', 'confidence': 1.0}, {'entity': 'acral skin', 'concept_id': 'C0444099', 'confidence': 0.7122198939323425}, {'entity': 'leukocytoclastic vasculitis', 'concept_id': 'C0151436', 'confidence': 1.0}, {'entity': 'nodular', 'concept_id': 'C0205297', 'confidence': 1.0}, {'entity': 'lesions', 'concept_id': 'C0221198', 'confidence': 1.0}], [{'entity': 'Granuloma faciale', 'concept_id': 'C0239495', 'confidence': 1.0}, {'entity': 'histologic', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'identical', 'concept_id': 'C0205280', 'confidence': 1.0}, {'entity': 'twin', 'concept_id': 'C0041427', 'confidence': 0.9999999403953552}, {'entity': 'process', 'concept_id': 'C1184743', 'confidence': 1.0}], [{'entity': 'Granuloma faciale', 'concept_id': 'C0239495', 'confidence': 1.0}, {'entity': 'leukocytoclastic vasculitis', 'concept_id': 'C0151436', 'confidence': 1.0}, {'entity': 'microscope', 'concept_id': 'C0181839', 'confidence': 1.0}], [{'entity': 'Chronic vasculitis', 'concept_id': 'C0042384', 'confidence': 0.7992802858352661}, {'entity': 'fibrotic nodules', 'concept_id': 'C0332561', 'confidence': 0.8351579308509827}], [{'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'associated with', 'concept_id': 'C0332281', 'confidence': 1.0}, {'entity': 'conditions', 'concept_id': 'C0012634', 'confidence': 0.8556983470916748}], [{'entity': 'Extracellular cholesterolosis', 'concept_id': 'C2973528', 'confidence': 0.9169934391975403}, {'entity': 'cholesterol clefts', 'concept_id': 'C3686582', 'confidence': 0.9999999403953552}, {'entity': 'yellowish nodules', 'concept_id': 'C1867455', 'confidence': 0.8135299682617188}], [{'entity': 'Nodules', 'concept_id': 'C0028259', 'confidence': 1.0}, {'entity': 'joints', 'concept_id': 'C0022417', 'confidence': 1.0}, {'entity': 'gout', 'concept_id': 'C0018099', 'confidence': 1.0}, {'entity': 'RA', 'concept_id': 'C0002893', 'confidence': 1.0}, {'entity': 'OE', 'concept_id': 'C1551089', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_48",
"caption_rating": "8"
},
{
"": "1007972",
"caption": "Stains used to exclude other entities include HMB45 melanin, S100, and STAT6.",
"image_path": "iklRyY1nBIE_image_25025022-8442-4585-8463-496487442b19.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['basal cell hyperplasia', 'infiltrating between benign glands', 'STOMP', 'prostatic stroma of sarcoma', 'HMB45 melanin', 'S100', 'STAT6']",
"noisy_text": " Something else you may have observed with this case is the fact that it's not just a stroma process. It looks like there's something else going on in the glands, too. And in the glands, it's almost like there's a crosstalk between the stroma process and the glands. The glands are benign, but they actually have what looks like basal cell hyperplasia in areas. And that's not uncommon with this entity. It is not unusual to have this entity, actually, with basal cell hyperplasia. The other observation I want to bring to your attention is the fact that this process is going in between benign glands, which means that it's almost respecting the benign glands next door. Because there are a number of processes that would destroy the adjacent benign glands and basically push them aside. But this process actually respects the benign glands, in quotes, and is actually going in between them, infiltrating in between them. And that's a clue to the diagnosis. Because as I hinted earlier, when you talk of tumors of the specialized prosthetic stroma, there are two main entities you think about. One is the so-called STOMP, stromal tumor of unsaturated malignant potential. And the other entity at the other extreme is the so-called prosthetic stroma of sarcoma. Some argue that there's some relationship between both of them that are in the spectrum. But what you're looking at right now in this case, based on what I've shown you, this type of atypia, it almost looks simplistic. It has this degenerative type of look to it. We are not seeing mitotic activity. For something this ugly or that looks this nasty, you'll expect to see necrosis, mitotic activity, and even destruction of the adjacent glands. But we're not seeing that. And that's kind of a perfect picture for so-called STOMP, stromal tumor of unsaturated malignant potential. As I said earlier, there's a relationship between this entity and prosthetic stroma of sarcoma. To start with, STOMPs can recur. About 15% of STOMPs can recur months or years after the initial resection. But about 15% to 20% of STOMPs may progress or may be associated with adjacent prosthetic stroma of sarcoma. So that's a very important thing to know. Because STOMP itself, as the name implies, is of unsaturated malignant potential. So it should not be downplayed. Because some of you may ask me, how do I sign all these cases? It's very important in your comments to document what I just said, that about 15% of these, if it's just STOMP is here on the H&E, nothing else, it's important to document that about 15% would recur. And more importantly, it's important to document that about 15% to 20% of these may be associated with or progress to prosthetic stroma of sarcoma. So it's not a case of they excise this and they leave the patient alone. They need to follow up these patients very closely. So that's very important to document in the report. So some of you may ask, OK, so what stains do we do for these cases? Obviously, you want to exclude a number of things. We talked about melanoma and other things. So you want to exclude those. So obviously, HMB45 melanin, those will be negative. Vimentin, which nobody uses anymore, is actually positive in this entity. PR could also be positive in this entity. Plus or minus CD34, plus or minus Desmin SMA, plus or minus ER may be positive, but it's usually negative. The pertinent negative stains are S100. I talked about the melanoma markers. And STAT6 is also negative. So it's very important to know that. So this is a stromal tumor of uncertain malignant potential. There have been a number of names for this entity over the years.",
"corrected_text": " Something else you may have observed with this case is the fact that it's not just a stroma process. It looks like there's something else going on in the glands, too. And in the glands, it's almost like there's a crosstalk between the stroma process and the glands. The glands are benign, but they actually have what looks like basal cell hyperplasia in areas. And that's not uncommon with this entity. It is not unusual to have this entity, actually, with basal cell hyperplasia. The other observation I want to bring to your attention is the fact that this process is going in between benign glands, which means that it's almost respecting the benign glands next door. Because there are a number of processes that would destroy the adjacent benign glands and basically push them aside. But this process actually respects the benign glands, in quotes, and is actually going in between them, infiltrating in between them. And that's a clue to the diagnosis. Because as I hinted earlier, when you talk of tumors of the specialized prosthetic stroma, there are two main entities you think about. One is the so-called STOMP, stromal tumor of unsaturated malignant potential. And the other entity at the other extreme is the so-called prosthetic stroma of sarcoma. Some argue that there's some relationship between both of them that are in the spectrum. But what you're looking at right now in this case, based on what I've shown you, this type of atypia, it almost looks simplistic. It has this degenerative type of look to it. We are not seeing mitotic activity. For something this ugly or that looks this nasty, you'expect to see necrosis, mitotic activity, and even destruction of the adjacent glands. But we're not seeing that. And that's kind of a perfect picture for so-called STOMP, stromal tumor of unsaturated malignant potential. As I said earlier, there's a relationship between this entity and prosthetic stroma of sarcoma. To start with, STOMPs can recur. About 15% of STOMPs can recur months or years after the initial resection. But about 15% to 20% of STOMPs may progress or may be associated with adjacent prosthetic stroma of sarcoma. So that's a very important thing to know. Because STOMP itself, as the name implies, is of unsaturated malignant potential. So it should not be downplayed. Because some of you may ask me, how do I sign all these cases? It's very important in your comments to document what I just said, that about 15% of these, if it's just STOMP is here on the H&E, nothing else, it's important to document that about 15% would recur. And more importantly, it's important to document that about 15% to 20% of these may be associated with or progress to prosthetic stroma of sarcoma. So it's not a case of they excise this and they leave the patient alone. They need to follow up these patients very closely. So that's very important to document in the report. So some of you may ask, OK, so what stains do we do for these cases? Obviously, you want to exclude a number of things. We talked about melanoma and other things. So you want to exclude those. So obviously, HMB45 melanin, those will be negative. Vimentin, which nobody uses anymore, is actually positive in this entity. PR could also be positive in this entity. Plus or minus CD34, plus or minus Desmin SMA, plus or minus ER may be positive, but it's usually negative. The pertinent negative stains are S100. I talked about the melanoma markers. And STAT6 is also negative. So it's very important to know that. So this is a stromal tumor of uncertain malignant potential. There have been a number of names for this entity over the years.",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'basal cell', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'benign glands', 'concept_id': 'C1301287', 'confidence': 0.726940393447876}, {'entity': 'entity', 'concept_id': 'C1551338', 'confidence': 1.0}], [{'entity': 'process', 'concept_id': 'C1184743', 'confidence': 1.0}, {'entity': 'infiltrating', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'benign glands', 'concept_id': 'C1301287', 'confidence': 0.726940393447876}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'atypia', 'concept_id': 'C0741302', 'confidence': 0.9999999403953552}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'consistent with', 'concept_id': 'C0332290', 'confidence': 1.0}, {'entity': 'STOMP', 'concept_id': 'C0056167', 'confidence': 0.6245664358139038}, {'entity': 'stromal tumor', 'concept_id': 'C0879615', 'confidence': 1.0}, {'entity': 'malignant', 'concept_id': 'C0205282', 'confidence': 1.0}, {'entity': 'potential', 'concept_id': 'C3245505', 'confidence': 1.0}], [{'entity': 'STOMPs', 'concept_id': 'C0577018', 'confidence': 0.6140404343605042}, {'entity': 'recur', 'concept_id': 'C0034897', 'confidence': 0.9999999403953552}, {'entity': 'progress', 'concept_id': 'C1272688', 'confidence': 1.0}, {'entity': 'prostatic stroma', 'concept_id': 'C1521760', 'confidence': 0.9999999403953552}, {'entity': 'sarcoma', 'concept_id': 'C1261473', 'confidence': 1.0}], [{'entity': 'Stains', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'entities', 'concept_id': 'C0424215', 'confidence': 0.7521668672561646}, {'entity': 'HMB45', 'concept_id': 'C1440756', 'confidence': 1.0}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}, {'entity': 'S100', 'concept_id': 'C3273837', 'confidence': 1.0}, {'entity': 'STAT6', 'concept_id': 'C0297890', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_49",
"caption_rating": "9"
},
{
"": "1005100",
"caption": "No involvement of the epidermis is seen.",
"image_path": "udoW6VSqsm4_image_51baed9e-eb48-4081-8853-ae258746f29c.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " Okay, so here we have a punch biopsy, non-equal skin. What we can see is there is a more sparse, moderate, and full trait in the superficial and deep dermis, and into the fat as well. And there's some eosinophilic component to it as well. Okay, what's the overall pattern? It's probably a superficial and deep, almost like a little funiculitis. It does go into the fat, and perivascular and interstitial. Yeah, and interstitial. And notice that there's no epidermal involved. No, epidermis is completely sparse. Even higher magnification. Now what do you see? Now I",
"corrected_text": " Okay, so here we have a punch biopsy, non-equal skin. What we can see is there is a more sparse, moderate, and full trait in the superficial and deep dermis, and into the fat as well. And there's some eosinophilic component to it as well. Okay, what's the overall pattern? It's probably a superficial and deep, almost like a little funiculitis. It does go into the fat, and perivascular and interstitial. Yeah, and interstitial. And notice that there's no epidermal involved. No, epidermis is completely sparse. Even higher magnification. Now what do you see? Now I",
"med_umls_ids": "[[{'entity': 'Punch biopsy', 'concept_id': 'C0182557', 'confidence': 1.0}, {'entity': 'normal skin', 'concept_id': 'C0558145', 'confidence': 1.0}, {'entity': 'moderate', 'concept_id': 'C0205081', 'confidence': 1.0}, {'entity': 'trait', 'concept_id': 'C0599883', 'confidence': 1.0}, {'entity': 'superficial', 'concept_id': 'C0205124', 'confidence': 1.0}, {'entity': 'deep dermis', 'concept_id': 'C0205125', 'confidence': 0.7651135921478271}, {'entity': 'fat', 'concept_id': 'C0015677', 'confidence': 1.0}], [{'entity': 'eosinophilic', 'concept_id': 'C0333930', 'confidence': 1.0}, {'entity': 'component', 'concept_id': 'C0449432', 'confidence': 1.0}, {'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}], [{'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}, {'entity': 'consistent with', 'concept_id': 'C0332290', 'confidence': 1.0}, {'entity': 'superficial', 'concept_id': 'C0205124', 'confidence': 1.0}, {'entity': 'deep funiculitis', 'concept_id': 'C0241216', 'confidence': 0.7899089455604553}, {'entity': 'perivascular', 'concept_id': 'C0442165', 'confidence': 1.0}, {'entity': 'interstitial regions', 'concept_id': 'C0596790', 'confidence': 0.7848911285400391}], [{'entity': 'involvement', 'concept_id': 'C1314939', 'confidence': 1.0}, {'entity': 'epidermis', 'concept_id': 'C0014520', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_50",
"caption_rating": "9"
},
{
"": "1006258",
"caption": "The case is an example of p63-positive prostate cancer.",
"image_path": "iklRyY1nBIE_image_e14ab13a-e981-42a6-8f7b-157c3d113a12.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['p63-positive prostate cancer', 'digital rectal examination', 'PSA levels', 'busy appearance', 'cribriform glands', 'p63-positive prostate cancer', 'digital rectal examination', 'PSA levels', 'busy appearance', 'cribriform glands']",
"noisy_text": " So this is another example of P63-positive prostate cancer. As you come over here, you can see it's the same process going on. Some of these glands look like conventional prostate cancer. This one looks like it's kind of undecided whether it should be P63-positive or conventional prostate cancer. As you come over here, this one looks like conventional prostate cancer. And then you have some others that are staining with P63. So this is another example of P63-positive prostate cancer. It's somewhat controversial whether to assign a glycine score to these. Obviously, if they form, if they have well-formed glands, that would be equivalent to glycine score 3 plus 3 equals 6 grade group 1. But the question is, the original case I showed you, when you have those polyform glands or single cells, it becomes debatable whether to assign a high glycine score to those cases. Because as of now, most of these tumors are relatively well-behaved. So that's still an area that is unsolved. So this was just a very good example of P63-positive prostate cancer. We'll move on to case 3. Case 3 is a 73-year-old man who presented with a positive digital rectal examination and elevated PSA levels. Again, you can see that a lot of the histories are beginning to overlap now. They look very similar. In this particular case, we have a different process going on. It's very busy. You can see there are a lot of glands, very, very busy. Very few benign glands there. There's some colonic tissue there. And as you keep looking at the core, you can see that there are some cribriform glands present. These glands,",
"corrected_text": " So this is another example of p63-positive prostate cancer. As you come over here, you can see it's the same process going on. Some of these glands look like conventional prostate cancer. This one looks like it's kind of undecided whether it should be p63-positive or conventional prostate cancer. As you come over here, this one looks like conventional prostate cancer. And then you have some others that are staining with P63. So this is another example of p63-positive prostate cancer. It's somewhat controversial whether to assign a glycine score to these. Obviously, if they form, if they have well-formed glands, that would be equivalent to glycine score 3 plus 3 equals 6 grade group 1. But the question is, the original case I showed you, when you have those polyform glands or single cells, it becomes debatable whether to assign a high glycine score to those cases. Because as of now, most of these tumors are relatively well-behaved. So that's still an area that is unsolved. So this was just a very good example of p63-positive prostate cancer. We'll move on to case 3. Case 3 is a 73-year-old man who presented with a positive digital rectal examination and elevated PSA levels. Again, you can see that a lot of the histories are beginning to overlap now. They look very similar. In this particular case, we have a different process going on. It's very busy. You can see there are a lot of glands, very, very busy. Very few benign glands there. There's some colonic tissue there. And as you keep looking at the core, you can see that there are some cribriform glands present. These glands,",
"med_umls_ids": "[[{'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'p63-positive', 'concept_id': 'C4329511', 'confidence': 0.5139493942260742}, {'entity': 'prostate cancer', 'concept_id': 'C0376358', 'confidence': 1.0}], [{'entity': 'glycine', 'concept_id': 'C0017890', 'confidence': 1.0}, {'entity': 'score', 'concept_id': 'C0449820', 'confidence': 1.0}, {'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}], [{'entity': 'Case 3', 'concept_id': 'C0868928', 'confidence': 0.8432309031486511}, {'entity': 'man', 'concept_id': 'C0025266', 'confidence': 1.0}, {'entity': 'positive digital rectal examination', 'concept_id': 'C0199900', 'confidence': 0.8765994906425476}, {'entity': 'elevated', 'concept_id': 'C0205250', 'confidence': 0.9999999403953552}, {'entity': 'PSA', 'concept_id': 'C0138741', 'confidence': 1.0}, {'entity': 'levels', 'concept_id': 'C0441889', 'confidence': 1.0}], [{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'benign glands', 'concept_id': 'C1301287', 'confidence': 0.726940393447876}, {'entity': 'cribriform glands', 'concept_id': 'C1285092', 'confidence': 0.6162902116775513}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_51",
"caption_rating": "7"
},
{
"": "1008610",
"caption": "Slightly hyperplastic epidermis and a cellular infiltrate throughout the dermis.",
"image_path": "8S4LeiO6Bbk_image_6d184866-3f35-4310-ae66-fee18077910a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['infiltrate filling the dermis and extending into the subcutaneous tissue', 'brown pigment near the surface', 'hyperplastic epidermis', 'cellular infiltrate throughout the dermis', 'infiltrate filling the dermis and extending into the subcutaneous tissue', 'brown pigment near the surface', 'hyperplastic epidermis', 'cellular infiltrate throughout the dermis']",
"noisy_text": " a large punch biopsy. And I think this actually was two punch biopsies from one lesion, each one bisected. And we can see that we've got an infiltrate filling the dermis and extending into the subcutaneous tissue. The infiltrate appears to be compressing the fat rather than growing in between the adipocytes. And I think it's scanning magnification, you know, one of the things that you can really begin to appreciate, not only the fact that this lesion is partially sampled, that it extends to the base and edges of the specimen, but one can begin to appreciate abundant hemorrhage within this tumor. And in addition, we can see some brown pigment near the surface. And common sense will tell you where there's smoke, there's fire. Since we do have all this abundant hemorrhage, there's a high probability that the pigment, this brownish gold pigment that we're seeing up near the surface of the specimen is likely hemocentaurant rather than melanin. But we'll confirm that when we go down to a higher power. As we move in, we can see that the epidermis is slightly hyperplastic. We've got this cellular infiltrate throughout the dermis and we'll need to go down and take a look at this infiltrate. It appears a little less dense at the",
"corrected_text": " a large punch biopsy. And I think this actually was two punch biopsies from one lesion, each one bisected. And we can see that we've got an infiltrate filling the dermis and extending into the subcutaneous tissue. The infiltrate appears to be compressing the fat rather than growing in between the adipocytes. And I think it's scanning magnification, you know, one of the things that you can really begin to appreciate, not only the fact that this lesion is partially sampled, that it extends to the base and edges of the specimen, but one can begin to appreciate abundant hemorrhage within this tumor. And in addition, we can see some brown pigment near the surface. And common sense will tell you where there's smoke, there's fire. Since we do have all this abundant hemorrhage, there's a high probability that the pigment, this brownish gold pigment that we're seeing up near the surface of the specimen is likely hemocentaurant rather than melanin. But we'confirm that when we go down to a higher power. As we move in, we can see that the epidermis is slightly hyperplastic. We've got this cellular infiltrate throughout the dermis and we'll need to go down and take a look at this infiltrate. It appears a little less dense at the",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'punch biopsy', 'concept_id': 'C0182557', 'confidence': 1.0}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'filling', 'concept_id': 'C0178866', 'confidence': 0.7777882218360901}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'subcutaneous tissue', 'concept_id': 'C0222331', 'confidence': 1.0}], [{'entity': 'Excessive', 'concept_id': 'C0442802', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'brown pigment near', 'concept_id': 'C4555503', 'confidence': 0.865685760974884}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}], [{'entity': 'hyperplastic epidermis', 'concept_id': 'C4748317', 'confidence': 0.7633129358291626}, {'entity': 'cellular infiltrate', 'concept_id': 'C1692321', 'confidence': 1.0}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_52",
"caption_rating": "8"
},
{
"": "1005878",
"caption": "Presence of hemocyanin-laden histiocytes and fascicles of histiocytes and fibrocytes with oval and fusiform nuclei.",
"image_path": "8S4LeiO6Bbk_image_84867427-b656-46b8-959a-78d245dc9193.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "[]",
"noisy_text": " course, one can always do special stains, an iron stain, such as Prussian blue or pearls for hemocentaurant and a Fontanumus song stain for melanin pigment. So in any case, getting back to the to the lesion in question, we've got a lot of hemocentaurant-laden histiocytes here. We've also got, in other areas, fascicles, kind of randomly oriented of histiocytes and fibrocytes with oval and fusiform nuclei. There's a little bit of nuclear pleomorphism, but if you know, we're not seeing any necrosis or an appreciable number of mitotic figures. And this large cellular fibrohystic-acidic infiltrate, again with the collagen trapping and ring siderophages out",
"corrected_text": " course, one can always do special stains, an iron stain, such as Prussian blue or pearls for hemocyanin and a Fontana-Masson stain for melanin pigment. So in any case, getting back to the to the lesion in question, we've got a lot of hemocyanin-laden histiocytes here. We've also got, in other areas, fascicles, kind of randomly oriented of histiocytes and fibrocytes with oval and fusiform nuclei. There's a little bit of nuclear pleomorphism, but if you know, we're not seeing any necrosis or an appreciable number of mitoses. And this large cellular fibrohystic-acidic infiltrate, again with the collagen trapping and ring siderophages out",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'hemocyanin-laden histiocytes', 'concept_id': 'C0019612', 'confidence': 0.6349639296531677}, {'entity': 'fascicles', 'concept_id': 'C1185741', 'confidence': 1.0}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'fibrocytes', 'concept_id': 'C0225332', 'confidence': 0.9999999403953552}, {'entity': 'oval', 'concept_id': 'C1709367', 'confidence': 1.0}, {'entity': 'fusiform nuclei', 'concept_id': 'C0332493', 'confidence': 0.7332888245582581}], [{'entity': 'necrosis', 'concept_id': 'C0027540', 'confidence': 1.0}, {'entity': 'mitoses', 'concept_id': 'C0026255', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_53",
"caption_rating": "9"
},
{
"": "1008441",
"caption": "Melanin granules within melanophages are more uniform in size and shape compared to hemosiderin pigment in centroblasts.",
"image_path": "8S4LeiO6Bbk_image_a620e8c7-c69d-45dd-a59c-1c1cbe14f75f.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Melanin granules within melanophages', 'Extravasated erythrocytes', 'Increased melanin in the basilar keratinocytes.', 'Melanin granules within melanophages', 'Extravasated erythrocytes', 'Increased melanin in the basilar keratinocytes.']",
"noisy_text": " or the melanophages is variable in size and shape. Now look at the melanin granules within this melanophage, and you can see that they're much more uniform in size and shape. Now look at the melanin granules within this melanophage, and you can see that they're much more uniform in size than the hemocentauric pigment in the centaurifages. It also tends to be a little bit darker staining, but sometimes it can be very difficult, tinctorially, depending upon the staining quality, to use color to distinguish the two, better to use size and context clues. Also note here we don't have any extravasated erythrocytes here, so much more likely to be melanin, and there's an increased melanin in the basilar keratinocytes. Getting back to the case, thin epidermis, bacular",
"corrected_text": " or the melanophages is variable in size and shape. Now look at the melanin granules within this melanophage, and you can see that they're much more uniform in size and shape. Now look at the melanin granules within this melanophage, and you can see that they're much more uniform in size than the hemosiderin pigment in the centroblasts. It also tends to be a little bit darker staining, but sometimes it can be very difficult, tinctorially, depending upon the staining quality, to use color to distinguish the two, better to use size and context clues. Also note here we don't have any extravasated erythrocytes here, so much more likely to be melanin, and there's an increased melanin in the basilar keratinocytes. Getting back to the case, thin epidermis, bacular",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'melanophages', 'concept_id': 'C3280463', 'confidence': 0.9375340938568115}, {'entity': 'variable size', 'concept_id': 'C1866144', 'confidence': 0.8559831976890564}, {'entity': 'shape', 'concept_id': 'C0332479', 'confidence': 1.0}], [{'entity': 'Melanin granules', 'concept_id': 'C0230692', 'confidence': 0.9174172878265381}, {'entity': 'melanophages', 'concept_id': 'C3280463', 'confidence': 0.9375340938568115}, {'entity': 'uniform', 'concept_id': 'C0205375', 'confidence': 1.0}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'shape', 'concept_id': 'C0332479', 'confidence': 1.0}, {'entity': 'hemosiderin', 'concept_id': 'C0019113', 'confidence': 1.0}, {'entity': 'pigment', 'concept_id': 'C0031911', 'confidence': 1.0}, {'entity': 'centroblasts', 'concept_id': 'C1517735', 'confidence': 0.8281925320625305}], [{'entity': 'Increased', 'concept_id': 'C0205217', 'confidence': 1.0}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}, {'entity': 'basilar keratinocytes', 'concept_id': 'C0022567', 'confidence': 0.803361713886261}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_54",
"caption_rating": "8"
},
{
"": "1006024",
"caption": "Lesions that stain with CD34 and are strongly positive for D240 are probably of lymphatic origin rather than vascular origin.",
"image_path": "8S4LeiO6Bbk_image_aa903496-ae7f-4150-9b54-0225f8d20fbe.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['dilated vascular channels', 'papillary projections', 'enlarged endothelial cells', 'compressed vascular channels', 'extravasated erythrocytes']",
"noisy_text": " which will slowly risk halt. These lesions will stain, frequently with CD34, but also are strongly positive for D240. So they probably are of lymphatic origin rather than vascular origin. What one looks for is a biphasic vascular tumor with this central area characterized by these dilated vascular channels. Let's look at the bottom piece, which frequently do contain these papillary projections, which protrude into the lumina, these plump endothelial cells, and then at the periphery, more compressed vascular channels, which dissect between collagen bundles. And it's at the periphery one frequently sees extravasated erythrocytes, siderophages, and",
"corrected_text": " which will slowly risk halt. These lesions will stain, frequently with CD34, but also are strongly positive for D240. So they probably are of lymphatic origin rather than vascular origin. What one looks for is a biphasic vascular tumor with this central area characterized by these dilated vascular channels. Let's look at the bottom piece, which frequently do contain these papillary projections, which protrude into the lumina, these plump endothelial cells, and then at the periphery, more compressed vascular channels, which dissect between collagen bundles. And it's at the periphery one frequently sees extravasated erythrocytes, siderophages, and",
"med_umls_ids": "[[{'entity': 'Lesions', 'concept_id': 'C0221198', 'confidence': 1.0}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'CD34', 'concept_id': 'C0054953', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'D240', 'concept_id': 'C3766973', 'confidence': 0.5323090553283691}, {'entity': 'lymphatic origin', 'concept_id': 'C0229889', 'confidence': 0.7706887125968933}, {'entity': 'vascular origin', 'concept_id': 'C0395959', 'confidence': 0.7819716334342957}], [{'entity': 'biphasic', 'concept_id': 'C0205184', 'confidence': 1.0}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'dilated', 'concept_id': 'C0700124', 'confidence': 0.9999999403953552}, {'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}, {'entity': 'central area', 'concept_id': 'C0929543', 'confidence': 0.8492603302001953}], [{'entity': 'Papillary projections', 'concept_id': 'C0016538', 'confidence': 0.7451471090316772}, {'entity': 'bottom piece', 'concept_id': 'C1511276', 'confidence': 0.722324788570404}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}], [{'entity': 'Enlarged endothelial cells', 'concept_id': 'C0423263', 'confidence': 0.7785332202911377}, {'entity': 'papillary projections', 'concept_id': 'C0016538', 'confidence': 0.7451471090316772}], [{'entity': 'Compressed vascular channels', 'concept_id': 'C1336948', 'confidence': 0.5993747711181641}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}], [{'entity': 'Extravasated', 'concept_id': 'C0015376', 'confidence': 0.868863582611084}, {'entity': 'erythrocytes', 'concept_id': 'C0014772', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_55",
"caption_rating": "9"
},
{
"": "1008549",
"caption": "Histopathology shows predominantly pink fibrous component and a lesser bluish myxoid component, consistent with fibromyxoid tumors.",
"image_path": "QDb68_G1HR4_image_effd7fd7-81c9-4878-a635-9a3264b82dde.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Predominantly pink fibrous component and a lesser myxoid bluish component.', 'Predominantly pink fibrous component and a lesser myxoid bluish component.']",
"noisy_text": " background fades out kind of quickly on H and E but the predominant color here is pink and I think this is one easy way to help remember this, fibromyxoid. The name says fibro before the word myxo. So the fibro is the pink part, the myxoid is the bluish pale part and these tumors usually not always but usually have a predominantly fibrous pink component and a lesser myxoid bluish component so it looks more pink. The way I also remember it is some of the original tumors that Dr. Evans described were misdiagnosed originally as either fibroma which is a good example of why it's dangerous to call",
"corrected_text": " background fades out kind of quickly on H and E but the predominant color here is pink and I think this is one easy way to help remember this, fibromyxoid. The name says fibro before the word myxoid. So the fibro is the pink part, the myxoid is the bluish pale part and these tumors usually not always but usually have a predominantly fibrous pink component and a lesser myxoid bluish component so it looks more pink. The way I also remember it is some of the original tumors that Dr. Evans described were misdiagnosed originally as either fibroma which is a good example of why it's dangerous to call",
"med_umls_ids": "[[{'entity': 'Histopathology', 'concept_id': 'C0243140', 'confidence': 1.0}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}, {'entity': 'consistent with', 'concept_id': 'C0332290', 'confidence': 1.0}, {'entity': 'fibromyxoid tumors', 'concept_id': 'C0205766', 'confidence': 0.9253939986228943}], [{'entity': 'Fibro', 'concept_id': 'C0016053', 'confidence': 0.9999999403953552}, {'entity': 'pink', 'concept_id': 'C0332585', 'confidence': 1.0}, {'entity': 'myxoid', 'concept_id': 'C0205295', 'confidence': 1.0}, {'entity': 'bluish pale part', 'concept_id': 'C0392768', 'confidence': 0.6970505118370056}], [{'entity': 'original', 'concept_id': 'C0205313', 'confidence': 1.0}, {'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'misdiagnosed', 'concept_id': 'C0679838', 'confidence': 0.896425724029541}, {'entity': 'fibroma', 'concept_id': 'C0016045', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_56",
"caption_rating": "9"
},
{
"": "1008181",
"caption": "Pseudomembranes can be caused by Clostridioides difficile colitis or ischemic injury.",
"image_path": "sDFjOtMAYrk_image_7a3e5842-9e70-46aa-9b43-ef5366ec922b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['Clostridioides difficile colitis', 'lamina propria', 'hyalinization']",
"noisy_text": " will give you pseudomembranes. Ischemic injury can also give it to you. And the one thing to note is that, so this patient had C. difficile colitis by laboratory, but he was not responding to treatment and they just decided to take a biopsy. And you can see here that in the lamina propria is not hyalinized. Now, does that mean that ischemia is excluded? No, because if it's, you know, it depends on the clinical history. If it's recent ischemia that happened within, I don't know, 24, 48 hours, you know, the hyalinopropia may not have had time to hyalinize. How",
"corrected_text": " will give you pseudomembranes. Ischemic injury can also give it to you. And the one thing to note is that, so this patient had C. difficile colitis by laboratory, but he was not responding to treatment and they just decided to take a biopsy. And you can see here that in the lamina propria is not hyalinized. Now, does that mean that ischemia is excluded? No, because if it's, you know, it depends on the clinical history. If it's recent ischemia that happened within, I don't know, 24, 48 hours, you know, the hyalinization may not have had time to hyalinize. How",
"med_umls_ids": "[[{'entity': 'Pseudomembranes', 'concept_id': 'C0240821', 'confidence': 1.0}, {'entity': 'Clostridioides', 'concept_id': 'C4406271', 'confidence': 1.0}, {'entity': 'colitis', 'concept_id': 'C0009319', 'confidence': 1.0}, {'entity': 'ischemic injury', 'concept_id': 'C2945681', 'confidence': 0.8915668725967407}], [{'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'hyalinization', 'concept_id': 'C0333438', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}, {'entity': 'hyalinization', 'concept_id': 'C0333438', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_57",
"caption_rating": "8"
},
{
"": "1008694",
"caption": "Trichofolliculoma with a cyst and miniaturized hair follicles adjacent to a central cyst.",
"image_path": "LlPaENuqzVQ_image_149214c6-8962-445f-97b4-994109a88c61.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['Trichofolliculoma with a cyst and miniaturized hair follicles', 'fibrous stroma', 'clefting between epithelium and stroma', 'clefting between epithelium and stroma']",
"noisy_text": " This is sort of a tricofolliculoma cut adjacent to the really the central cyst. And the tricofolliculoma has got a little cyst with these little miniaturized hair follicles that are radiating from the central cyst component of the lesion. So this is off to the side of it. But you can see that these follicular neoplasms, they pretty much commonly do have this stroma that you see with it that's more fibrous as opposed to fibromucinous. And that's helpful. It's not a criterion for the diagnosis necessarily every time, but it's a helpful finding when you see it because you don't usually get clefting between the epithelium and the stroma in these lesions as opposed to a basal cell carcinoma where you do. So that's a tricofolliculoma kind of cut to the side. OK, let's",
"corrected_text": " This is sort of a trichofolliculoma cut adjacent to the really the central cyst. And the trichofolliculoma has got a little cyst with these little miniaturized hair follicles that are radiating from the central cyst component of the lesion. So this is off to the side of it. But you can see that these follicular neoplasms, they pretty much commonly do have this stroma that you see with it that's more fibrous as opposed to fibromyxoid. And that's helpful. It's not a criterion for the diagnosis necessarily every time, but it's a helpful finding when you see it because you don't usually get clefting between the epithelium and the stroma in these lesions as opposed to a basal cell carcinoma where you do. So that's a trichofolliculoma kind of cut to the side. OK, let's",
"med_umls_ids": "[[{'entity': 'Trichofolliculoma', 'concept_id': 'C0334262', 'confidence': 1.0}, {'entity': 'cyst', 'concept_id': 'C0010709', 'confidence': 1.0}, {'entity': 'miniaturized hair follicles', 'concept_id': 'C0221971', 'confidence': 0.7287319302558899}, {'entity': 'adjacent', 'concept_id': 'C0205117', 'confidence': 1.0}, {'entity': 'central cyst', 'concept_id': 'C0205099', 'confidence': 0.7124271988868713}], [{'entity': 'Follicular', 'concept_id': 'C0439682', 'confidence': 1.0}, {'entity': 'neoplasms', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'fibrous stroma', 'concept_id': 'C1180207', 'confidence': 0.8035051226615906}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'Clefting', 'concept_id': 'C4021813', 'confidence': 0.8906428217887878}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'stroma', 'concept_id': 'C0927195', 'confidence': 1.0}, {'entity': 'lesions', 'concept_id': 'C0221198', 'confidence': 1.0}, {'entity': 'basal cell carcinoma', 'concept_id': 'C0007117', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_58",
"caption_rating": "8"
},
{
"": "1005368",
"caption": "No prominent nuclei or cribriform/micropapillary formation.",
"image_path": "r7OA0Trj5hQ_image_5c9b2e40-bd92-4380-abe2-0f704419ab72.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " So the polarity is maintained. Okay, so those two points are very important. And the third one is no prominent nuclei. Nuclei are not prominent. And the fourth point is, no cribriformic or micropapillary formation. So the predominant features you see here is the maintained polarity, nuclei reaching the middle third of the cells, no prominent nuclei, cribriformic or micropapillary. This is the criteria for low grade dysplasia. Compare it with here. Here the cells are coming and touching the top. Can you all see",
"corrected_text": " So the polarity is maintained. Okay, so those two points are very important. And the third one is no prominent nuclei. Nuclei are not prominent. And the fourth point is, no cribriform or micropapillary formation. So the predominant features you see here is the maintained polarity, nuclei reaching the middle third of the cells, no prominent nuclei, cribriform or micropapillary. This is the criteria for low grade dysplasia. Compare it with here. Here the cells are coming and touching the top. Can you all see",
"med_umls_ids": "[[{'entity': 'Maintained', 'concept_id': 'C1314677', 'confidence': 1.0}, {'entity': 'polarity', 'concept_id': 'C0596963', 'confidence': 1.0}], [{'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'cribriform/micropapillary formation', 'concept_id': 'C1621425', 'confidence': 0.5390191674232483}], [{'entity': 'Criteria', 'concept_id': 'C0243161', 'confidence': 0.9999998807907104}, {'entity': 'low', 'concept_id': 'C0205251', 'confidence': 0.9999999403953552}], [{'entity': 'sentence', 'concept_id': 'C0876929', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_59",
"caption_rating": "8"
},
{
"": "1005522",
"caption": "Poorly differentiated cells and high grade malignancy are present in the biopsy.",
"image_path": "r7OA0Trj5hQ_image_b0cdca07-dc48-47e6-bb70-cb4ff9138176.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['signet ring cells', 'poorly differentiated cells', 'gastric biopsy', 'colonic biopsy', 'signet ring cells', 'poorly differentiated cells', 'gastric biopsy', 'colonic biopsy']",
"noisy_text": " And this, I got it again from Twitter, I think from Sanjay Bhavatiya, pathologists who missed signet cells, pathologists who are missing the signet cells, pathologists who will be missing the signet cell carcinoma. So it's a very, very, very difficult condition. We have to keep our eyes wide. Leave open to see these signet cells, especially in biopsies. Here, what is happening? Very poorly differentiated cells, high grade malignancy. Again, definitely, it is proliferative disease with the ATP. Again, invasion metastasis, we cannot see from this picture. But whenever you see this much of poorly differentiated cells in the gastric biopsy or in the colonic biopsy, and predominantly the atypical",
"corrected_text": " And this, I got it again from Twitter, I think from Sanjay Bhavatiya, pathologists who missed signet cells, pathologists who are missing the signet cells, pathologists who will be missing the signet cell carcinoma. So it's a very, very, very difficult condition. We have to keep our eyes wide. Leave open to see these signet cells, especially in biopsies. Here, what is happening? Very poorly differentiated cells, high grade malignancy. Again, definitely, it is proliferative disease with the ATP. Again, invasion metastasis, we cannot see from this picture. But whenever you see this much of poorly differentiated cells in the gastric biopsy or in the colonic biopsy, and predominantly the atypical",
"med_umls_ids": "[[{'entity': 'Signet cell carcinoma', 'concept_id': 'C0206696', 'confidence': 0.9410539865493774}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'pathologists', 'concept_id': 'C0334866', 'confidence': 1.0}, {'entity': 'signet ring cells', 'concept_id': 'C0333727', 'confidence': 1.0}], [{'entity': 'Poorly differentiated cells', 'concept_id': 'C0205617', 'confidence': 0.9036805629730225}, {'entity': 'high', 'concept_id': 'C0205250', 'confidence': 1.0}, {'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}], [{'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'proliferative disease', 'concept_id': 'C1332629', 'confidence': 0.8737467527389526}, {'entity': 'ATP', 'concept_id': 'C0001480', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_60",
"caption_rating": "9"
},
{
"": "1004917",
"caption": "Description of normal colonic glands and crypts with no lymphocytes, plasma cells, or eosinophils. The amount of lamina propria in between the crypts is the same as you move from one crypt to another.",
"image_path": "sDFjOtMAYrk_image_4d5b53cd-2d73-4e48-aac1-d4d00440aff0.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['colonic crypts', 'muscularis mucosa', 'lamina propria']",
"noisy_text": " fellows about normal. What I like to see are these colonic glands. Do we have an arrow? Oh, yes. It should. Is he not coming up? No. Oh, you have to turn it on. No, it's not coming up. Yeah, it is. Yeah, here you go. Just the red one. Yeah. Oh, I don't see it. It's okay. Is the mouse going to work? Yeah, I'll do the mouse. Yeah, it works. Okay. Basically, I like to see my colonic crypts nice and straight coming from the surface, trying to kiss that muscularis mucosa underneath in between the crypts and the muscularis mucosa. I don't want to see any lymphocytes, plasma cells, eosinophils. You can have one or two. That's okay, but typically no basal lymphoplasma cytosis. The other thing I like to point out is the amount of lamina propria in between the crypts is the same as you move from one crypt to another. The crypts stand equidistant one from another. Remember the differences between the cecum or the right colon and the left colon. This is a biopsy from the segment and shows",
"corrected_text": " fellows about normal. What I like to see are these colonic glands. Do we have an arrow? Oh, yes. It should. Is he not coming up? No. Oh, you have to turn it on. No, it's not coming up. Yeah, it is. Yeah, here you go. Just the red one. Yeah. Oh, I don't see it. It's okay. Is the mouse going to work? Yeah, I'll do the mouse. Yeah, it works. Okay. Basically, I like to see my colonic crypts nice and straight coming from the surface, trying to kiss that muscularis mucosa underneath in between the crypts and the muscularis mucosa. I don't want to see any lymphocytes, plasma cells, eosinophils. You can have one or two. That's okay, but typically no basal lymphoplasma cytosis. The other thing I like to point out is the amount of lamina propria in between the crypts is the same as you move from one crypt to another. The crypts stand equidistant one from another. Remember the differences between the cecum or the right colon and the left colon. This is a biopsy from the segment and shows",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'colonic glands', 'concept_id': 'C0227351', 'confidence': 0.8191195130348206}, {'entity': 'crypts', 'concept_id': 'C0227427', 'confidence': 0.9071587324142456}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'amount', 'concept_id': 'C1265611', 'confidence': 0.9999998807907104}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'crypts', 'concept_id': 'C0227427', 'confidence': 0.9071587324142456}, {'entity': 'crypt', 'concept_id': 'C1880192', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_61",
"caption_rating": "9"
},
{
"": "1004936",
"caption": "Lamina propria is expanded and there is a degree of inflammatory lamina propria, suggesting IBD in the differential diagnosis.",
"image_path": "sDFjOtMAYrk_image_1c682c2e-09fe-4fbd-91f0-03b0fe894763.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['glands are trying to keep their shapes', 'lamina propria is expanded', 'degree of architectural distortion', 'inflammatory lamina propria']",
"noisy_text": " There's a little bit of distortion. I would give you that. But overall, the glands are trying to keep their distance. They're equally distant one from another and they're trying to keep their shapes overall. I wouldn't say the architecture is perfect, but overall, they're trying to retain it. And you mentioned whether this was from the right or left. And that's a good question. I would say, since this is from the rectum, the lamina propria is actually expanded. So, I would say it's too cellular for rectum. So, I think IBD would be definitely in the differential with that degree of architectural distortion maybe, but with that degree of inflammatory lamina propria expansion. But let's look",
"corrected_text": " There's a little bit of distortion. I would give you that. But overall, the glands are trying to keep their distance. They're equally distant one from another and they're trying to keep their shapes overall. I wouldn't say the architecture is perfect, but overall, they're trying to retain it. And you mentioned whether this was from the right or left. And that's a good question. I would say, since this is from the rectum, the lamina propria is actually expanded. So, I would say it's too cellular for rectum. So, I think IBD would be definitely in the differential with that degree of architectural distortion maybe, but with that degree of inflammatory lamina propria expansion. But let's look",
"med_umls_ids": "[[{'entity': 'Glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'distant', 'concept_id': 'C0443203', 'confidence': 1.0}, {'entity': 'shapes', 'concept_id': 'C0332479', 'confidence': 1.0}, {'entity': 'overall', 'concept_id': 'C0282416', 'confidence': 1.0}, {'entity': 'architectural distortion', 'concept_id': 'C2826609', 'confidence': 1.0}], [{'entity': 'Lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'degree', 'concept_id': 'C0441889', 'confidence': 1.0}, {'entity': 'inflammatory', 'concept_id': 'C0333348', 'confidence': 1.0}, {'entity': 'IBD', 'concept_id': 'C0021390', 'confidence': 1.0}, {'entity': 'differential diagnosis', 'concept_id': 'C0011906', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_62",
"caption_rating": "8"
},
{
"": "1008447",
"caption": "Low-grade fibromyxoid sarcomas with swirling growth can mimic perineuriomas and often express Clodin-1.",
"image_path": "QDb68_G1HR4_image_8772a4d0-5e6a-4322-9ff2-d521cda51a2d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Deep soft tissue', 'Perineurioma', 'Low-grade fibromyxoid sarcoma', 'Immunohistochemistry', 'Swirling growth', 'Deep soft tissue', 'Perineurioma', 'Low-grade fibromyxoid sarcoma', 'Immunohistochemistry', 'Swirling growth']",
"noisy_text": " involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is more of a difficult problem because perineurioma has a lot of overlap histologically with low-grade fibromyxoid sarcoma and also immunohistochemically. On immunostains, EMA, Clodin-1 and Glut-1 are three immunostains that will usually stain perineuriomas. The problem is that low-grade fibromyxoid sarcomas often express at least focal EMA, so that's a problem and additionally, the examples of low-grade fibromyxoid sarcoma that have dramatic swirling and whirling growth, those are the ones that have a perineurioma like pattern, the ones that mimic perineurioma. They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The",
"corrected_text": " involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is more of a difficult problem because perineurioma has a lot of overlap histologically with low-grade fibromyxoid sarcoma and also immunohistochemically. On immunostains, EMA, Clodin-1 and Glut-1 are three immunostains that will usually stain perineuriomas. The problem is that low-grade fibromyxoid sarcomas often express at least focal EMA, so that's a problem and additionally, the examples of low-grade fibromyxoid sarcoma that have dramatic swirling and whirling growth, those are the ones that have a perineurioma like pattern, the ones that mimic perineurioma. They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The",
"med_umls_ids": "[[{'entity': 'CD34', 'concept_id': 'C0054953', 'confidence': 1.0}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'deep soft tissue tumors', 'concept_id': 'C0037579', 'confidence': 0.8622524738311768}], [{'entity': 'Perineurioma', 'concept_id': 'C0751691', 'confidence': 0.9999999403953552}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'histologically', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'immunohistochemistry', 'concept_id': 'C0021044', 'confidence': 0.9999998807907104}], [{'entity': 'EMA', 'concept_id': 'C0268596', 'confidence': 0.9999999403953552}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}, {'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'immunohistochemical stains', 'concept_id': 'C4317108', 'confidence': 0.9999999403953552}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibrosarcomas', 'concept_id': 'C0016057', 'confidence': 1.0}, {'entity': 'EMA', 'concept_id': 'C0268596', 'confidence': 0.9999999403953552}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}], [{'entity': 'Low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'swirling', 'concept_id': 'C0233591', 'confidence': 0.7064549922943115}, {'entity': 'growth', 'concept_id': 'C0018270', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'express', 'concept_id': 'C0017262', 'confidence': 0.8176293969154358}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}], [{'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'reports', 'concept_id': 'C0684224', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcomas', 'concept_id': 'C1275282', 'confidence': 0.8123146891593933}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_63",
"caption_rating": "9"
},
{
"": "1009196",
"caption": "The narrator mentions cellular intramuscular myxoma and the challenges in differentiating it from fibrous and more cellular areas.",
"image_path": "QDb68_G1HR4_image_559a6539-9ae0-45d0-8273-a583aa8f043a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['myxoid features', 'fine delicate collagen', 'cellular intramuscular myxoma', 'fibrous areas', 'cellular areas', 'MUC4 stain']",
"noisy_text": " Here's again the myxoid background I really think this is very helpful. The very very fine delicate collagen that you see. Now areas like this I think can kind of resemble what you see in a so-called cellular intramuscular myxoma. Intramuscular myxomas are usually very blue and myxoid very hypocellular but sometimes they get more fibrous and more cellular areas. And on a needle biopsy I think that can be challenging. So I think usually with some experience you can tell them apart on H and E most of the time but when I have any doubt I just do a MUC4 stain. The MUC4 is negative and on a needle it looks like a myxoma with some kind of fibrous or a little bit more cellular areas and then I just say that it's probably a cellular intramuscular myxoma. So I think MUC4",
"corrected_text": " Here's again the myxoid background I really think this is very helpful. The very very fine delicate collagen that you see. Now areas like this I think can kind of resemble what you see in a so-called cellular intramuscular myxoma. Intramuscular myxomas are usually very blue and myxoid very hypocellular but sometimes they get more fibrous and more cellular areas. And on a needle biopsy I think that can be challenging. So I think usually with some experience you can tell them apart on H and E most of the time but when I have any doubt I just do a MUC4 stain. The MUC4 is negative and on a needle it looks like a myxoma with some kind of fibrous or a little bit more cellular areas and then I just say that it's probably a cellular intramuscular myxoma. So I think MUC4",
"med_umls_ids": "[[{'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'myxoid', 'concept_id': 'C0205295', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}], [{'entity': 'narrator', 'concept_id': 'C1135957', 'confidence': 0.7711340188980103}, {'entity': 'cellular', 'concept_id': 'C0007634', 'confidence': 0.9999999403953552}, {'entity': 'intramuscular', 'concept_id': 'C0442117', 'confidence': 1.0}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}, {'entity': 'cellular areas', 'concept_id': 'C0007634', 'confidence': 0.7882957458496094}], [{'entity': 'MUC4', 'concept_id': 'C1417496', 'confidence': 0.9999999403953552}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'confirm', 'concept_id': 'C0521093', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'cellular intramuscular myxoma', 'concept_id': 'C1334260', 'confidence': 0.8910117149353027}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_64",
"caption_rating": "7"
},
{
"": "1009473",
"caption": "Perineurioma can be difficult to diagnose because it overlaps with low-grade fibromyxoid sarcoma histologically and on immunohistochemistry.",
"image_path": "QDb68_G1HR4_image_1e4ca39c-40f6-492b-b7c7-c8e20bfaf5f5.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Deep soft tissue', 'Perineurioma', 'Low-grade fibromyxoid sarcoma', 'Immunohistochemistry', 'Swirling growth']",
"noisy_text": " involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is more of a difficult problem because perineurioma has a lot of overlap histologically with low-grade fibromyxoid sarcoma and also immunohistochemically. On immunostains, EMA, Clodin-1 and Glut-1 are three immunostains that will usually stain perineuriomas. The problem is that low-grade fibromyxoid sarcomas often express at least focal EMA, so that's a problem and additionally, the examples of low-grade fibromyxoid sarcoma that have dramatic swirling and whirling growth, those are the ones that have a perineurioma like pattern, the ones that mimic perineurioma. They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The",
"corrected_text": " involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is more of a difficult problem because perineurioma has a lot of overlap histologically with low-grade fibromyxoid sarcoma and also immunohistochemically. On immunostains, EMA, Clodin-1 and Glut-1 are three immunostains that will usually stain perineuriomas. The problem is that low-grade fibromyxoid sarcomas often express at least focal EMA, so that's a problem and additionally, the examples of low-grade fibromyxoid sarcoma that have dramatic swirling and whirling growth, those are the ones that have a perineurioma like pattern, the ones that mimic perineurioma. They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The",
"med_umls_ids": "[[{'entity': 'CD34', 'concept_id': 'C0054953', 'confidence': 1.0}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'deep soft tissue tumors', 'concept_id': 'C0037579', 'confidence': 0.8622524738311768}], [{'entity': 'Perineurioma', 'concept_id': 'C0751691', 'confidence': 0.9999999403953552}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'histologically', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'immunohistochemistry', 'concept_id': 'C0021044', 'confidence': 0.9999998807907104}], [{'entity': 'EMA', 'concept_id': 'C0268596', 'confidence': 0.9999999403953552}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}, {'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'immunohistochemical stains', 'concept_id': 'C4317108', 'confidence': 0.9999999403953552}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibrosarcomas', 'concept_id': 'C0016057', 'confidence': 1.0}, {'entity': 'EMA', 'concept_id': 'C0268596', 'confidence': 0.9999999403953552}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}], [{'entity': 'Low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'swirling', 'concept_id': 'C0233591', 'confidence': 0.7064549922943115}, {'entity': 'growth', 'concept_id': 'C0018270', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'express', 'concept_id': 'C0017262', 'confidence': 0.8176293969154358}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}], [{'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'reports', 'concept_id': 'C0684224', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcomas', 'concept_id': 'C1275282', 'confidence': 0.8123146891593933}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_65",
"caption_rating": "8"
},
{
"": "1004436",
"caption": "Sections will be taken from the entire lesion to ensure there are no zones that have become more cancerous or aggressive.",
"image_path": "LlPaENuqzVQ_image_0827e0c8-1f0d-4227-b777-830b8dac8a2d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " and then it becomes much more aggressive. So that's why I'm going to do them with soft tissue. You have to think more of geography. You have to say, we're going to look at this entire thing and we're going to take sections from the whole thing because we want to make sure there's not zones in which it's become more cancerous, more aggressive in those areas. So this lesion probably started off as a benign lyomyoma. So I think in some areas it doesn't look very atypical. Right there, that's pretty typical appearing lyomyoma. Other areas though, you see there's zones of pleomorphism and some spindle-shaped cells that are quite very",
"corrected_text": " and then it becomes much more aggressive. So that's why I'm going to do them with soft tissue. You have to think more of geography. You have to say, we're going to look at this entire thing and we're going to take sections from the whole thing because we want to make sure there's not zones in which it's become more cancerous, more aggressive in those areas. So this lesion probably started off as a benign leiomyoma. So I think in some areas it doesn't look very atypical. Right there, that's pretty typical appearing lyomyoma. Other areas though, you see there's zones of pleomorphism and some spindle cells that are quite very",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'aggressive', 'concept_id': 'C0001807', 'confidence': 1.0}, {'entity': 'soft tissue', 'concept_id': 'C0225317', 'confidence': 0.9999999403953552}], [{'entity': 'Sections', 'concept_id': 'C0007876', 'confidence': 0.8770228624343872}, {'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'zones', 'concept_id': 'C1710706', 'confidence': 0.8182461857795715}, {'entity': 'cancerous', 'concept_id': 'C1514391', 'confidence': 0.763753354549408}, {'entity': 'aggressive', 'concept_id': 'C0001807', 'confidence': 1.0}], [{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'benign leiomyoma', 'concept_id': 'C0023267', 'confidence': 0.9082092046737671}], [{'entity': 'zones', 'concept_id': 'C1710706', 'confidence': 0.8182461857795715}, {'entity': 'pleomorphism', 'concept_id': 'C0032219', 'confidence': 1.0}, {'entity': 'spindle cells', 'concept_id': 'C0682540', 'confidence': 1.0}, {'entity': 'areas', 'concept_id': 'C0205146', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_66",
"caption_rating": "8"
},
{
"": "1006853",
"caption": "The epidermis is hyperplastic and papillary, with altered quantified layer and some compact ortho and parakeratosis.",
"image_path": "8S4LeiO6Bbk_image_64d4d5f2-c090-4c46-9f31-a82730e67136.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['hyperplastic epidermis', 'papillary epidermis', 'compact ortho', 'parakeratosis', 'patchy perivascular infiltrative lymphocytes', 'discrete columns and mounds of parakeratosis', 'dyskeratotic cells', 'verruciform xanthoma']",
"noisy_text": " that the epidermis is hyperplastic and gently papillated. The quantified layer is altered somewhat. We got some compact ortho and probably a little bit of pericaratosis here are to tell at this power. The underlying dermis contains a patchy perivascular infiltrative lymphocytes and if we move to higher power, we can confirm these findings. Lymphocytes, dilated vessels, papillomatosis, and epidermal hyperplasia. There are discrete columns and mounds of pericaratosis within the stratum corneum and some dyskeratotic cells within the underlying epidermis. One of the things when one sees these these columns of bright pink pericaratosis that one might think about would be a verruciform xanthoma because you'll remember we tend to get these vertical",
"corrected_text": " that the epidermis is hyperplastic and gently papillated. The quantified layer is altered somewhat. We got some compact ortho and probably a little bit of parakeratosis here are to tell at this power. The underlying dermis contains a patchy perivascular infiltrative lymphocytes and if we move to higher power, we can confirm these findings. Lymphocytes, dilated vessels, papillomatosis, and epidermal hyperplasia. There are discrete columns and mounds of parakeratosis within the stratum corneum and some dyskeratotic cells within the underlying epidermis. One of the things when one sees these these columns of bright pink pericaratosis that one might think about would be a verruciform xanthoma because you'remember we tend to get these vertical",
"med_umls_ids": "[[{'entity': 'epidermis', 'concept_id': 'C0014520', 'confidence': 1.0}, {'entity': 'hyperplastic', 'concept_id': 'C0020507', 'confidence': 1.0}, {'entity': 'papillary', 'concept_id': 'C0205312', 'confidence': 1.0}, {'entity': 'quantified', 'concept_id': 'C1709793', 'confidence': 0.6807526350021362}, {'entity': 'layer', 'concept_id': 'C0934502', 'confidence': 1.0}, {'entity': 'compact ortho', 'concept_id': 'C1333134', 'confidence': 0.7191344499588013}, {'entity': 'parakeratosis', 'concept_id': 'C0030436', 'confidence': 1.0}], [{'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'perivascular', 'concept_id': 'C0442165', 'confidence': 1.0}], [{'entity': 'Discrete columns', 'concept_id': 'C0227428', 'confidence': 0.6879350543022156}, {'entity': 'mounds', 'concept_id': 'C2717795', 'confidence': 0.736616313457489}, {'entity': 'parakeratosis', 'concept_id': 'C0030436', 'confidence': 1.0}, {'entity': 'stratum corneum', 'concept_id': 'C0221921', 'confidence': 1.0}, {'entity': 'dyskeratotic cells', 'concept_id': 'C1512098', 'confidence': 0.8970272541046143}, {'entity': 'epidermis', 'concept_id': 'C0014520', 'confidence': 1.0}], [{'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'verruciform xanthoma', 'concept_id': 'C0346054', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_67",
"caption_rating": "8"
},
{
"": "1004834",
"caption": "Evidence of aspiration is present, with food-like products found in a bronchial unit.",
"image_path": "jF_pj4-tEC8_image_8a47c2f7-b51c-4c9e-8adb-a5c2bfb78396.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Pulmonary', 'Cardiac', 'Gastrointestinal']",
"roi_text": "['food-like products in bronchial unit', 'aspiration']",
"noisy_text": " there's a bronchial units with food like products in it, you got meat there and vegetables within the bronchiola unit, so there's evidence of aspiration, this could be an agonal aspiration as the person was struggling for air, and so some of the gastric content may have come up and went up into the bronchial lungs, but we'll talk more about that as well, let me continue to peruse around because there's an area that I want to really focus on, and then we'll talk about the bronchiola unit, I think this may be one of those areas, and then we'll",
"corrected_text": " there's a bronchial units with food like products in it, you got meat there and vegetables within the bronchiolar unit, so there's evidence of aspiration, this could be an agonal aspiration as the person was struggling for air, and so some of the gastric content may have come up and went up into the bronchial lungs, but we'talk more about that as well, let me continue to peruse around because there's an area that I want to really focus on, and then we'talk about the bronchiolar unit, I think this may be one of those areas, and then we'll",
"med_umls_ids": "[[{'entity': 'Evidence', 'concept_id': 'C3887511', 'confidence': 1.0}, {'entity': 'aspiration', 'concept_id': 'C0349707', 'confidence': 1.0}, {'entity': 'food-like products', 'concept_id': 'C0681562', 'confidence': 0.6498357057571411}, {'entity': 'bronchial unit', 'concept_id': 'C0205039', 'confidence': 0.8046900629997253}], [{'entity': 'agonal aspiration', 'concept_id': 'C2315245', 'confidence': 0.8239514827728271}, {'entity': 'person', 'concept_id': 'C0027361', 'confidence': 1.0}, {'entity': 'air', 'concept_id': 'C0001861', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "608.0",
"id": "test_68",
"caption_rating": "8"
},
{
"": "1007567",
"caption": "Cells become more round and epithelioid and cluster around the edge of the rosette.",
"image_path": "QDb68_G1HR4_image_4042b6aa-9f8f-4c44-ba15-d0118de0f971.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Perivascular pseudorosette', 'Neurofibroma', 'Fibroblastic tumor']",
"noisy_text": " a vessel in the middle but look what we're seeing here on the edge is what's described that you often see the other case didn't show it nicely but around the edge of the rosettes the cells tend to get more round and almost epithelioid and kind of cluster around the edge of the rosette so I think that's a really good example here of kind of a collagen rosette and the larger kind of more round but still very bland and monomorphic uniform cells that surround the edge of the collagen rosettes when you see those rosettes in this tumor so collagen rosettes in a fibroblastic tumor should be an instant clue that you're probably dealing with a low-grade",
"corrected_text": " a vessel in the middle but look what we're seeing here on the edge is what's described that you often see the other case didn't show it nicely but around the edge of the rosettes the cells tend to get more round and almost epithelioid and kind of cluster around the edge of the rosette so I think that's a really good example here of kind of a collagen rosette and the larger kind of more round but still very bland and monomorphic uniform cells that surround the edge of the collagen rosettes when you see those rosettes in this tumor so collagen rosettes in a fibroblastic tumor should be an instant clue that you're probably dealing with a low-grade",
"med_umls_ids": "[[{'entity': 'Perivascular', 'concept_id': 'C0442165', 'confidence': 1.0}, {'entity': 'pseudorosette', 'concept_id': 'C1335569', 'confidence': 0.8461084365844727}, {'entity': 'edge', 'concept_id': 'C0205154', 'confidence': 1.0}, {'entity': 'rosettes', 'concept_id': 'C0035863', 'confidence': 0.8847858905792236}, {'entity': 'neurofibroma', 'concept_id': 'C0027830', 'confidence': 1.0}], [{'entity': 'Cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'round', 'concept_id': 'C0332490', 'confidence': 1.0}, {'entity': 'epithelioid', 'concept_id': 'C0014603', 'confidence': 0.8891293406486511}, {'entity': 'cluster', 'concept_id': 'C1555715', 'confidence': 1.0}, {'entity': 'edge', 'concept_id': 'C0205154', 'confidence': 1.0}, {'entity': 'rosette', 'concept_id': 'C0035863', 'confidence': 1.0}], [{'entity': 'Neurofibroma', 'concept_id': 'C0027830', 'confidence': 1.0}, {'entity': 'fibroblastic tumor', 'concept_id': 'C0206643', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_69",
"caption_rating": "7"
},
{
"": "1006032",
"caption": "Immunofluorescence pattern shows absence of Ig and presence of C3.",
"image_path": "udoW6VSqsm4_image_6f8b09d3-0b63-4ad7-b0a9-acf69e1eb6f5.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['subepidermal bullous lesion', 'bullous pemphigoid', 'microscope', 'pregnant woman', 'immunofluorescence pattern', 'Ig', 'C3', 'Ig']",
"noisy_text": " So EBA, DH, PCT. You don't have to go through the entire... I'm just subepidermal. I'm just going through them. I don't know what's the... What if this is a 25-year-old pregnant woman? Oh, gestational. Yeah, pemphigoid gestation. And that's what this is in this case. It looks exactly like bullous pemphigoid under the microscope. You can't tell it apart. So always think of it. And what's the immunofluorescence pattern that we can see? So you would see Ig, not Ag? No Ig at all. No, okay, no. But what do you see? I'm not sure. Anybody know? C3. Linear complement",
"corrected_text": " So EBA, DH, PCT. You don't have to go through the entire... I'm just subepidermal. I'm just going through them. I don't know what's the... What if this is a 25-year-old pregnant woman? Oh, gestational. Yeah, pemphigoid gestation. And that's what this is in this case. It looks exactly like bullous pemphigoid under the microscope. You can't tell it apart. So always think of it. And what's the immunofluorescence pattern that we can see? So you would see Ig, not Ag? No Ig at all. No, okay, no. But what do you see? I'm not sure. Anybody know? C3. Linear complement",
"med_umls_ids": "[[{'entity': 'Subepidermal', 'concept_id': 'C0221935', 'confidence': 0.8599841594696045}, {'entity': 'bullous lesion', 'concept_id': 'C0005758', 'confidence': 1.0}, {'entity': 'bullous pemphigoid', 'concept_id': 'C0030805', 'confidence': 0.9999999403953552}, {'entity': 'microscope', 'concept_id': 'C0181839', 'confidence': 1.0}, {'entity': 'pemphigoid', 'concept_id': 'C0030805', 'confidence': 0.9999999403953552}, {'entity': 'gestation', 'concept_id': 'C0032961', 'confidence': 1.0}, {'entity': 'pregnant woman', 'concept_id': 'C0033011', 'confidence': 1.0}], [{'entity': 'Immunofluorescence pattern', 'concept_id': 'C0016318', 'confidence': 0.8741495609283447}, {'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'Ig', 'concept_id': 'C0021027', 'confidence': 1.0}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'C3', 'concept_id': 'C1305853', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_70",
"caption_rating": "8"
},
{
"": "1008420",
"caption": "Homogenization necrosis of collagen bundles is present, along with scattered stellate fibroblasts.",
"image_path": "udoW6VSqsm4_image_1409c112-ae10-4526-82a6-7a5b2ea13a1a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['Homogenization necrosis of collagen bundles', 'Stellate fibroblasts', 'Telangiectasis', 'Bizarre and irregular blood vessels', 'Fibroblasts with irregular and bizarre morphology']",
"noisy_text": " There's homogenization of collagen bundles. There's all of this. There's very few scattered little stellate fibroblasts. Yeah, good. So, what's the diagnosis? It's chronic radiation dermatitis. Yeah, chronic radiation dermatitis. And this is probably from the radiation. Now, it looks like solar elastosis. There may be some solar elastosis also. But if you radiate somebody's skin, they get elastotic material also. So, UV is not the only thing that causes that. You can get solar elastosis. You can also get radiation-induced elastosis. So, this is chronic radiation dermatitis in this case. You can get telangiectasis. Sometimes the blood vessels can be kind of bizarre and irregular also, fibroblasts can be stellated and irregular and bizarre. So, I don't remember what this patient had, why they were radiated, but this was chronic radiodermatitis. And they often",
"corrected_text": " There's homogenization of collagen bundles. There's all of this. There's very few scattered little stellate fibroblasts. Yeah, good. So, what's the diagnosis? It's chronic radiation dermatitis. Yeah, chronic radiation dermatitis. And this is probably from the radiation. Now, it looks like solar elastosis. There may be some solar elastosis also. But if you radiate somebody's skin, they get elastotic material also. So, UV is not the only thing that causes that. You can get solar elastosis. You can also get radiation-induced elastosis. So, this is chronic radiation dermatitis in this case. You can get telangiectasis. Sometimes the blood vessels can be kind of bizarre and irregular also, fibroblasts can be stellate and irregular and bizarre. So, I don't remember what this patient had, why they were radiated, but this was chronic radiodermatitis. And they often",
"med_umls_ids": "[[{'entity': 'Homogenization necrosis', 'concept_id': 'C0027540', 'confidence': 0.5868868231773376}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'bundles', 'concept_id': 'C3658308', 'confidence': 0.8706014752388}, {'entity': 'scattered', 'concept_id': 'C0439742', 'confidence': 1.0}, {'entity': 'stellate', 'concept_id': 'C0205141', 'confidence': 0.9999999403953552}, {'entity': 'fibroblasts', 'concept_id': 'C0016030', 'confidence': 1.0}], [{'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'chronic radiation dermatitis', 'concept_id': 'C0263607', 'confidence': 1.0}, {'entity': 'radiation', 'concept_id': 'C0034519', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_71",
"caption_rating": "9"
},
{
"": "1004579",
"caption": "The absence of hyalinization in the lamina propria does not exclude ischemia, as recent ischemia may not have had time to cause hyalinization.",
"image_path": "sDFjOtMAYrk_image_0887edbf-5f48-4747-8342-2d4f7a6e89b5.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['Clostridioides difficile colitis', 'lamina propria', 'hyalinization', 'Clostridioides difficile colitis', 'lamina propria', 'hyalinization']",
"noisy_text": " will give you pseudomembranes. Ischemic injury can also give it to you. And the one thing to note is that, so this patient had C. difficile colitis by laboratory, but he was not responding to treatment and they just decided to take a biopsy. And you can see here that in the lamina propria is not hyalinized. Now, does that mean that ischemia is excluded? No, because if it's, you know, it depends on the clinical history. If it's recent ischemia that happened within, I don't know, 24, 48 hours, you know, the hyalinopropia may not have had time to hyalinize. How",
"corrected_text": " will give you pseudomembranes. Ischemic injury can also give it to you. And the one thing to note is that, so this patient had C. difficile colitis by laboratory, but he was not responding to treatment and they just decided to take a biopsy. And you can see here that in the lamina propria is not hyalinized. Now, does that mean that ischemia is excluded? No, because if it's, you know, it depends on the clinical history. If it's recent ischemia that happened within, I don't know, 24, 48 hours, you know, the hyalinization may not have had time to hyalinize. How",
"med_umls_ids": "[[{'entity': 'Pseudomembranes', 'concept_id': 'C0240821', 'confidence': 1.0}, {'entity': 'Clostridioides', 'concept_id': 'C4406271', 'confidence': 1.0}, {'entity': 'colitis', 'concept_id': 'C0009319', 'confidence': 1.0}, {'entity': 'ischemic injury', 'concept_id': 'C2945681', 'confidence': 0.8915668725967407}], [{'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'hyalinization', 'concept_id': 'C0333438', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}, {'entity': 'hyalinization', 'concept_id': 'C0333438', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_72",
"caption_rating": "9"
},
{
"": "1004448",
"caption": "The pattern is consistent with superficial and deep funiculitis, involving the perivascular and interstitial regions.",
"image_path": "udoW6VSqsm4_image_59d0e5dd-f50c-497c-afb3-e8743731f6f9.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " Okay, so here we have a punch biopsy, non-equal skin. What we can see is there is a more sparse, moderate, and full trait in the superficial and deep dermis, and into the fat as well. And there's some eosinophilic component to it as well. Okay, what's the overall pattern? It's probably a superficial and deep, almost like a little funiculitis. It does go into the fat, and perivascular and interstitial. Yeah, and interstitial. And notice that there's no epidermal involved. No, epidermis is completely sparse. Even higher magnification. Now what do you see? Now I",
"corrected_text": " Okay, so here we have a punch biopsy, non-equal skin. What we can see is there is a more sparse, moderate, and full trait in the superficial and deep dermis, and into the fat as well. And there's some eosinophilic component to it as well. Okay, what's the overall pattern? It's probably a superficial and deep, almost like a little funiculitis. It does go into the fat, and perivascular and interstitial. Yeah, and interstitial. And notice that there's no epidermal involved. No, epidermis is completely sparse. Even higher magnification. Now what do you see? Now I",
"med_umls_ids": "[[{'entity': 'Punch biopsy', 'concept_id': 'C0182557', 'confidence': 1.0}, {'entity': 'normal skin', 'concept_id': 'C0558145', 'confidence': 1.0}, {'entity': 'moderate', 'concept_id': 'C0205081', 'confidence': 1.0}, {'entity': 'trait', 'concept_id': 'C0599883', 'confidence': 1.0}, {'entity': 'superficial', 'concept_id': 'C0205124', 'confidence': 1.0}, {'entity': 'deep dermis', 'concept_id': 'C0205125', 'confidence': 0.7651135921478271}, {'entity': 'fat', 'concept_id': 'C0015677', 'confidence': 1.0}], [{'entity': 'eosinophilic', 'concept_id': 'C0333930', 'confidence': 1.0}, {'entity': 'component', 'concept_id': 'C0449432', 'confidence': 1.0}, {'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}], [{'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}, {'entity': 'consistent with', 'concept_id': 'C0332290', 'confidence': 1.0}, {'entity': 'superficial', 'concept_id': 'C0205124', 'confidence': 1.0}, {'entity': 'deep funiculitis', 'concept_id': 'C0241216', 'confidence': 0.7899089455604553}, {'entity': 'perivascular', 'concept_id': 'C0442165', 'confidence': 1.0}, {'entity': 'interstitial regions', 'concept_id': 'C0596790', 'confidence': 0.7848911285400391}], [{'entity': 'involvement', 'concept_id': 'C1314939', 'confidence': 1.0}, {'entity': 'epidermis', 'concept_id': 'C0014520', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_73",
"caption_rating": "9"
},
{
"": "1004556",
"caption": "No form material was found upon examination with routine and polarized light, and PAS, GMS, AFB, and tissue gram states were negative for organisms.",
"image_path": "hoV-JkD6Wb0_image_35c387bb-6546-430f-be13-a9ecf212d0a0.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['immune cells', 'dilated vessels', 'mononuclear cells', 'immune cells', 'dilated vessels', 'mononuclear cells']",
"noisy_text": " consistent with the clinical picture of edema. And again, we've got these collections of, let me see if I can lock the slide in, collections of epithelioid histiocytes within the dermis, some adjacent to dilated vessels, and a brief, or not a brief, a very subtle cuff of mononuclear cells. Examination of these sections with routine and polarized light revealed no form material. And PAS, GMS, AFB, and tissue gram states were negative for organisms. And on the basis of these changes and the clinical presentation, a diagnosis of metastatic Crohn's disease was",
"corrected_text": " consistent with the clinical picture of edema. And again, we've got these collections of, let me see if I can lock the slide in, collections of epithelioid histiocytes within the dermis, some adjacent to dilated vessels, and a brief, or not a brief, a very subtle cuff of mononuclear cells. Examination of these sections with routine and polarized light revealed no form material. And PAS, GMS, AFB, and tissue gram states were negative for organisms. And on the basis of these changes and the clinical presentation, a diagnosis of metastatic Crohn's disease was",
"med_umls_ids": "[[{'entity': 'Collections', 'concept_id': 'C0600644', 'confidence': 0.8663196563720703}, {'entity': 'immune cells', 'concept_id': 'C4330475', 'confidence': 0.8268961906433105}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'adjacent', 'concept_id': 'C0205117', 'confidence': 1.0}, {'entity': 'dilated vessels', 'concept_id': 'C0424830', 'confidence': 0.8255378603935242}, {'entity': 'cuff', 'concept_id': 'C0441107', 'confidence': 1.0}, {'entity': 'mononuclear cells', 'concept_id': 'C0806987', 'confidence': 1.0}, {'entity': 'consistent with', 'concept_id': 'C0332290', 'confidence': 1.0}, {'entity': 'clinical picture', 'concept_id': 'C4313895', 'confidence': 0.8534306883811951}, {'entity': 'edema', 'concept_id': 'C0013604', 'confidence': 0.9999999403953552}], [{'entity': 'No form', 'concept_id': 'C0348078', 'confidence': 0.840075671672821}, {'entity': 'material', 'concept_id': 'C0520510', 'confidence': 1.0}, {'entity': 'examination', 'concept_id': 'C0031809', 'confidence': 1.0}, {'entity': 'routine', 'concept_id': 'C0205547', 'confidence': 1.0}, {'entity': 'polarized light', 'concept_id': 'C0599025', 'confidence': 0.9999999403953552}, {'entity': 'PAS', 'concept_id': 'C0030125', 'confidence': 1.0}, {'entity': 'GMS', 'concept_id': 'C4764197', 'confidence': 0.6768916845321655}, {'entity': 'AFB', 'concept_id': 'C0483226', 'confidence': 1.0}, {'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'gram states', 'concept_id': 'C1301808', 'confidence': 0.7144557237625122}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'organisms', 'concept_id': 'C0029235', 'confidence': 0.9999998807907104}], [{'entity': \"Metastatic Crohn's disease\", 'concept_id': 'C1304174', 'confidence': 0.923439621925354}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'changes', 'concept_id': 'C0392747', 'confidence': 1.0}, {'entity': 'clinical presentation', 'concept_id': 'C4554564', 'confidence': 0.8858868479728699}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_74",
"caption_rating": "10"
},
{
"": "1007671",
"caption": "The material surrounding the cyst is cheesy sebaceous material, typical of a dermoid cyst or mature cystic teratoma of the ovary.",
"image_path": "3mRB9j0eyVM_image_052d39e2-dd4d-40e9-9cd4-224a3eaaec61.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gynecologic', 'Hematopathology', 'Soft tissue']",
"roi_text": "['Cheesy sebaceous material surrounding the cyst.', 'Stratified squamous epithelium lining of the mature cystic teratoma.']",
"noisy_text": " material that is cheesy sebaceous material that is surrounding this cyst. So this is a typical gross picture of a dermoid cyst or the cystic teratoma, mature cystic teratoma of the ovary. This is the histological picture of this mature cystic teratoma. The lining epithelium is stratified squamous epithelium along with the skin adenexa that are the sebaceous glands and the sweat glands. So this is all about the mature cystic. Then the germ cell tumors, malignant germ cell tumors, these are rare. 3% of the ovarian cancers are malignant germ cell tumors.",
"corrected_text": " material that is cheesy sebaceous material that is surrounding this cyst. So this is a typical gross picture of a dermoid cyst or the cystic teratoma, mature cystic teratoma of the ovary. This is the histological picture of this mature cystic teratoma. The lining epithelium is stratified squamous epithelium along with the skin adnexa that are the sebaceous glands and the sweat glands. So this is all about the mature cystic. Then the germ cell tumors, malignant germ cell tumors, these are rare. 30% of the ovarian cancers are malignant germ cell tumors.",
"med_umls_ids": "[[{'entity': 'material', 'concept_id': 'C0520510', 'confidence': 1.0}, {'entity': 'cyst', 'concept_id': 'C0010709', 'confidence': 1.0}, {'entity': 'cheesy', 'concept_id': 'C0423381', 'confidence': 0.7845876812934875}, {'entity': 'sebaceous material', 'concept_id': 'C0221947', 'confidence': 0.7280718088150024}, {'entity': 'dermoid cyst', 'concept_id': 'C0011649', 'confidence': 1.0}, {'entity': 'mature', 'concept_id': 'C0205286', 'confidence': 1.0}, {'entity': 'cystic teratoma', 'concept_id': 'C0011649', 'confidence': 0.9999998807907104}, {'entity': 'ovary', 'concept_id': 'C0029939', 'confidence': 1.0}], [{'entity': 'lining', 'concept_id': 'C0205132', 'confidence': 1.0}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'mature', 'concept_id': 'C0205286', 'confidence': 1.0}, {'entity': 'cystic teratoma', 'concept_id': 'C0011649', 'confidence': 0.9999998807907104}, {'entity': 'stratified', 'concept_id': 'C0205363', 'confidence': 1.0}, {'entity': 'squamous epithelium', 'concept_id': 'C0221909', 'confidence': 1.0}, {'entity': 'skin adnexa', 'concept_id': 'C0001575', 'confidence': 0.8680230379104614}, {'entity': 'sebaceous', 'concept_id': 'C0221947', 'confidence': 0.8709007501602173}, {'entity': 'sweat glands', 'concept_id': 'C0038989', 'confidence': 1.0}], [{'entity': 'Malignant germ cell tumors', 'concept_id': 'C4048549', 'confidence': 0.9233970046043396}, {'entity': 'rare', 'concept_id': 'C0521114', 'confidence': 1.0}, {'entity': 'ovarian cancers', 'concept_id': 'C1140680', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "960.0",
"id": "test_75",
"caption_rating": "10"
},
{
"": "1006855",
"caption": "Discrete columns and mounds of parakeratosis within the stratum corneum and dyskeratotic cells within the underlying epidermis.",
"image_path": "8S4LeiO6Bbk_image_64d4d5f2-c090-4c46-9f31-a82730e67136.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['hyperplastic epidermis', 'papillary epidermis', 'compact ortho', 'parakeratosis', 'patchy perivascular infiltrative lymphocytes', 'discrete columns and mounds of parakeratosis', 'dyskeratotic cells', 'verruciform xanthoma']",
"noisy_text": " that the epidermis is hyperplastic and gently papillated. The quantified layer is altered somewhat. We got some compact ortho and probably a little bit of pericaratosis here are to tell at this power. The underlying dermis contains a patchy perivascular infiltrative lymphocytes and if we move to higher power, we can confirm these findings. Lymphocytes, dilated vessels, papillomatosis, and epidermal hyperplasia. There are discrete columns and mounds of pericaratosis within the stratum corneum and some dyskeratotic cells within the underlying epidermis. One of the things when one sees these these columns of bright pink pericaratosis that one might think about would be a verruciform xanthoma because you'll remember we tend to get these vertical",
"corrected_text": " that the epidermis is hyperplastic and gently papillated. The quantified layer is altered somewhat. We got some compact ortho and probably a little bit of parakeratosis here are to tell at this power. The underlying dermis contains a patchy perivascular infiltrative lymphocytes and if we move to higher power, we can confirm these findings. Lymphocytes, dilated vessels, papillomatosis, and epidermal hyperplasia. There are discrete columns and mounds of parakeratosis within the stratum corneum and some dyskeratotic cells within the underlying epidermis. One of the things when one sees these these columns of bright pink pericaratosis that one might think about would be a verruciform xanthoma because you'remember we tend to get these vertical",
"med_umls_ids": "[[{'entity': 'epidermis', 'concept_id': 'C0014520', 'confidence': 1.0}, {'entity': 'hyperplastic', 'concept_id': 'C0020507', 'confidence': 1.0}, {'entity': 'papillary', 'concept_id': 'C0205312', 'confidence': 1.0}, {'entity': 'quantified', 'concept_id': 'C1709793', 'confidence': 0.6807526350021362}, {'entity': 'layer', 'concept_id': 'C0934502', 'confidence': 1.0}, {'entity': 'compact ortho', 'concept_id': 'C1333134', 'confidence': 0.7191344499588013}, {'entity': 'parakeratosis', 'concept_id': 'C0030436', 'confidence': 1.0}], [{'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'perivascular', 'concept_id': 'C0442165', 'confidence': 1.0}], [{'entity': 'Discrete columns', 'concept_id': 'C0227428', 'confidence': 0.6879350543022156}, {'entity': 'mounds', 'concept_id': 'C2717795', 'confidence': 0.736616313457489}, {'entity': 'parakeratosis', 'concept_id': 'C0030436', 'confidence': 1.0}, {'entity': 'stratum corneum', 'concept_id': 'C0221921', 'confidence': 1.0}, {'entity': 'dyskeratotic cells', 'concept_id': 'C1512098', 'confidence': 0.8970272541046143}, {'entity': 'epidermis', 'concept_id': 'C0014520', 'confidence': 1.0}], [{'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'verruciform xanthoma', 'concept_id': 'C0346054', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_76",
"caption_rating": "10"
},
{
"": "1004455",
"caption": "Presence of H. pylori in the luminal area or lumen.",
"image_path": "r7OA0Trj5hQ_image_8b04be78-c890-4686-bd2f-aed9e7558f4c.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['H. pylori in the oil immersion', 'Goblet cells in the stomach', 'Mucin in the stomach is neutral', 'Goblet cells in the stomach', 'Mucin in the stomach is neutral']",
"noisy_text": " Here, now we are coming to cytology. You see in the intra-luminal area or in the lumen, you see a lot of comma-shaped rods sitting on the epithelium, not going into the epithelium. So these are all the H. pylori in the oil immersion. Here, the surface epithelium shows goblet cells, and these are all biopsies from the stomach. So when you see goblet cells in the stomach, it is intestinal metaplasia. Another thing you have to remember, the stomach is having an acid milieu, acid environment, but the mucin in the stomach is neutral, whereas the intestinal mucin is acidic. That's why in PAS, the acidic mucin is taking the asian blue color, whereas the",
"corrected_text": " Here, now we are coming to cytology. You see in the luminal area or in the lumen, you see a lot of comma-shaped rods sitting on the epithelium, not going into the epithelium. So these are all the H. pylori in the oil immersion. Here, the surface epithelium shows goblet cells, and these are all biopsies from the stomach. So when you see goblet cells in the stomach, it is intestinal metaplasia. Another thing you have to remember, the stomach is having an acid milieu, acid environment, but the mucin in the stomach is neutral, whereas the intestinal mucin is acidic. That's why in PAS, the acidic mucin is taking the asian blue color, whereas the",
"med_umls_ids": "[[{'entity': 'Cytological', 'concept_id': 'C0205471', 'confidence': 0.9999998807907104}, {'entity': 'stomach biopsies', 'concept_id': 'C0005558', 'confidence': 0.7603482604026794}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'H. pylori', 'concept_id': 'C0079488', 'confidence': 1.0}, {'entity': 'luminal area', 'concept_id': 'C0524462', 'confidence': 0.7778207659721375}, {'entity': 'lumen', 'concept_id': 'C0524461', 'confidence': 0.9999998807907104}], [{'entity': 'Goblet cells', 'concept_id': 'C0506994', 'confidence': 0.9999999403953552}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'intestinal metaplasia', 'concept_id': 'C0334037', 'confidence': 1.0}], [{'entity': 'Difference', 'concept_id': 'C1705241', 'confidence': 1.0}, {'entity': 'acidity', 'concept_id': 'C0001128', 'confidence': 1.0}, {'entity': 'mucin', 'concept_id': 'C0026682', 'confidence': 1.0}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'intestine', 'concept_id': 'C0021853', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_77",
"caption_rating": "8"
},
{
"": "1006533",
"caption": "DFSP is the only neoplasm that diffusely infiltrates between and among lipocytes in a diffuse pattern like this.",
"image_path": "LlPaENuqzVQ_image_51cecd4e-d855-4e9f-87d5-a4f71e68be44.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['honeycomb morphology', 'lipocytes', 'typical storiform pattern', 'lipocytes']",
"noisy_text": " this is a clue to this diagnosis. You can make this diagnosis at low power when you see this pattern. This is a honeycomb morphology. Rarely anything does this except dramatic fibrosarcoma tuberans. Okay, when you see this pattern, you can impress your friends and colleagues. You can say, this is DFSB. You don't need the storiform pattern. If you see this, you got the diagnosis. No other neoplasm really gets diffusely between and among lipocytes in a diffuse pattern like this, other than DFSB. Now you look up here and yeah, you do have the nice, beautiful storiform pattern here. And you don't really need a CD34 stain here. You can do it",
"corrected_text": " this is a clue to this diagnosis. You can make this diagnosis at low power when you see this pattern. This is a honeycomb morphology. Rarely anything does this except desmoplastic fibroblastoma. Okay, when you see this pattern, you can impress your friends and colleagues. You can say, this is DFSP. You don't need the typical storiform pattern. If you see this, you got the diagnosis. No other neoplasm really gets diffusely between and among lipocytes in a diffuse pattern like this, other than DFSP. Now you look up here and yeah, you do have the nice, typical typical storiform pattern here. And you don't really need a CD34 stain here. You can do it",
"med_umls_ids": "[[{'entity': 'Honeycomb', 'concept_id': 'C0332468', 'confidence': 1.0}, {'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'desmoplastic fibroblastoma', 'concept_id': 'C0206645', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}], [{'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}, {'entity': 'neoplasm', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'diffusely', 'concept_id': 'C0205219', 'confidence': 0.8011853098869324}, {'entity': 'lipocytes', 'concept_id': 'C0206131', 'confidence': 1.0}, {'entity': 'diffuse pattern', 'concept_id': 'C1333299', 'confidence': 0.9999998807907104}], [{'entity': 'storiform pattern', 'concept_id': 'C1336510', 'confidence': 0.8142904043197632}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_78",
"caption_rating": "8"
},
{
"": "1006088",
"caption": "The cells or melanocytes in this case are vesicular and type A.",
"image_path": "zhzJ9pgCvuw_image_ae04f709-8557-46a4-90c7-3cf7136436dd.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Hematopathology']",
"roi_text": "['Melanocytes are vesicular and type A.', 'Nevoid melanoma.']",
"noisy_text": " cells or these melanocytes are vesicular that you like they're type a cells uh so you add all that up and this is what it is this is a nevoid melanoma no i'm not going to go gazing looking for mitotic triggers but uh they they they will be there if not in this section they'll be present in the next section and i don't think you need to do any immunohistochemistry on this case it's that's just what it is a lot of people get on search and then they think gosh i need to do something so what you could do if you really wanted to you could do an hmb",
"corrected_text": " cells or these melanocytes are vesicular that you like they're type a cells uh so you add all that up and this is what it is this is a nevoid melanoma no i'm not going to go gazing looking for mitotic triggers but uh they they they will be there if not in this section they'll be present in the next section and i don't think you need to do any immunohistochemistry on this case it's that's just what it is a lot of people get on search and then they think gosh i need to do something so what you could do if you really wanted to you could do an hmb",
"med_umls_ids": "[[{'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'vesicular', 'concept_id': 'C0205378', 'confidence': 1.0}], [{'entity': 'nevoid melanoma', 'concept_id': 'C1882081', 'confidence': 1.0}], [{'entity': 'Mitotic', 'concept_id': 'C1513354', 'confidence': 1.0}, {'entity': 'triggers', 'concept_id': 'C0032930', 'confidence': 1.0}, {'entity': 'next section', 'concept_id': 'C0205117', 'confidence': 0.7968209981918335}], [{'entity': 'No immunohistochemistry', 'concept_id': 'C0021044', 'confidence': 0.9730632901191711}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_79",
"caption_rating": "8"
},
{
"": "1009290",
"caption": "The criteria for dysplasia include loss of cellular polarity and nuclei reaching the surface.",
"image_path": "r7OA0Trj5hQ_image_c1797725-96e3-4257-958d-a33f2d51e511.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Nuclei reaching the surface', 'Cribriform and micropapillary patterns', 'Nuclei reaching the surface', 'Cribriform and micropapillary patterns']",
"noisy_text": " And the criteria are loss of polarity, nuclei reaching the surface. Here you can see nuclei reaching the surface. Prominent nuclei, if you see carefully for 10 seconds, you can start seeing the nuclei and cribriformic and micropapillary. This concept of dysplasia, low-grade dysplasia and high-grade dysplasia is very, very essential because you can apply this criteria in any organ. You can apply it in the pancreas. You can apply it in the gallbladder. You can apply it in the bile duct. Even you can apply it in the breast. You can apply it in the prostate. You can apply it",
"corrected_text": " And the criteria are loss of polarity, nuclei reaching the surface. Here you can see nuclei reaching the surface. Prominent nuclei, if you see carefully for 10 seconds, you can start seeing the nuclei and cribriform and micropapillary. This concept of dysplasia, low-grade dysplasia and high-grade dysplasia is very, very essential because you can apply this criteria in any organ. You can apply it in the pancreas. You can apply it in the gallbladder. You can apply it in the bile duct. Even you can apply it in the breast. You can apply it in the prostate. You can apply it",
"med_umls_ids": "[[{'entity': 'criteria', 'concept_id': 'C0243161', 'confidence': 0.9999998807907104}, {'entity': 'dysplasia', 'concept_id': 'C0334044', 'confidence': 1.0}, {'entity': 'loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'cellular polarity', 'concept_id': 'C0085304', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}], [{'entity': 'Prominent', 'concept_id': 'C0205402', 'confidence': 0.9999999403953552}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'cribriform', 'concept_id': 'C1621425', 'confidence': 0.9999999403953552}, {'entity': 'micropapillary', 'concept_id': 'C1290608', 'confidence': 0.891559898853302}, {'entity': 'patterns', 'concept_id': 'C0449774', 'confidence': 1.0}, {'entity': 'indicative', 'concept_id': 'C2985705', 'confidence': 0.7675144076347351}, {'entity': 'dysplasia', 'concept_id': 'C0334044', 'confidence': 1.0}], [{'entity': 'concept', 'concept_id': 'C0178566', 'confidence': 1.0}, {'entity': 'dysplasia', 'concept_id': 'C0334044', 'confidence': 1.0}, {'entity': 'essential', 'concept_id': 'C0205224', 'confidence': 0.9999999403953552}, {'entity': 'organs', 'concept_id': 'C0178784', 'confidence': 1.0}, {'entity': 'pancreas', 'concept_id': 'C0030274', 'confidence': 0.9999999403953552}, {'entity': 'gallbladder', 'concept_id': 'C0016976', 'confidence': 0.9999999403953552}, {'entity': 'bile duct', 'concept_id': 'C0005400', 'confidence': 1.0}, {'entity': 'breast', 'concept_id': 'C0006141', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_80",
"caption_rating": "9"
},
{
"": "1004643",
"caption": "Intestinal metaplasia is present.",
"image_path": "r7OA0Trj5hQ_image_6383bc61-ea49-4ba7-b64c-3752ed875092.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['muscle fibers', 'intestinal metaplasia', 'lamina propria', 'muscle fibers', 'intestinal metaplasia', 'lamina propria']",
"noisy_text": " where, again, you can see the muscle fibers running into the lamina propria. If you are in doubt, you can use the trichrome strain, where you can identify the muscle running up there. And you can see nice intestinal metaplasia there. Again, the number of glands are less in here. So this is chronic atrophic gastritis with intestinal metaplasia with muscularization of the lamina propria. More than one pathology involved in this biopsy. Plastic changes seen above are known as TIS. Once they cross the muscular ischemicosa, then only they are eligible for T1. So muscular ischemicosa acts like",
"corrected_text": " where, again, you can see the muscle fibers running into the lamina propria. If you are in doubt, you can use the trichrome strain, where you can identify the muscle running up there. And you can see nice intestinal metaplasia there. Again, the number of glands are less in here. So this is chronic atrophic gastritis with intestinal metaplasia with muscularization of the lamina propria. More than one pathology involved in this biopsy. Plastic changes seen above are known as TIS. Once they cross the muscularis propria, then only they are eligible for T1. So muscularis propria acts like",
"med_umls_ids": "[[{'entity': 'Muscle fibers', 'concept_id': 'C0242697', 'confidence': 1.0}, {'entity': 'running', 'concept_id': 'C0035953', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}], [{'entity': 'Intestinal metaplasia', 'concept_id': 'C0334037', 'confidence': 1.0}], [{'entity': 'Chronic atrophic gastritis', 'concept_id': 'C0017154', 'confidence': 1.0}, {'entity': 'intestinal metaplasia', 'concept_id': 'C0334037', 'confidence': 1.0}, {'entity': 'muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'Plastic changes', 'concept_id': 'C0392747', 'confidence': 0.7598782777786255}, {'entity': 'TIS', 'concept_id': 'C0475413', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_81",
"caption_rating": "8"
},
{
"": "1008327",
"caption": "The glands seen in the image are pyloric gland metaplasia, which can be seen in colitis, end-associated injury, and mycophenol-associated injury.",
"image_path": "sDFjOtMAYrk_image_7ba03594-d61b-4022-b5a1-5bc3ff58a9de.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['pyloric gland metaplasia', 'solid organ transplant recipient', 'eosinophils', 'pyloric gland metaplasia', 'solid organ transplant recipient', 'eosinophils']",
"noisy_text": " Yeah, these cells, these glands right here. What is it? Yeah, exactly. It's a pyloric glomeruloplasia. So pyloric glomeruloplasia should be Crohn's. No, you can see pyloric glomeruloplasia in your sort of a colitis and end-associated injury and also in microphenol-associated injury, as this case is. And the tip of the patient is a solid organ transplant recipient. with microphenol-associated injury have many more in the way of eosinophils, a lot more in the way of eosinophils than GVHD patients do. So that's really, really helpful. Is there",
"corrected_text": " Yeah, these cells, these glands right here. What is it? Yeah, exactly. It's a pyloric gland metaplasia. So pyloric gland metaplasia should be Crohn's. No, you can see pyloric gland metaplasia in your sort of a colitis and end-associated injury and also in mycophenol-associated injury, as this case is. And the tip of the patient is a solid organ transplant recipient. with mycophenol-associated injury have many more in the way of eosinophils, a lot more in the way of eosinophils than GVHD patients do. So that's really, really helpful. Is there",
"med_umls_ids": "[[{'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'image', 'concept_id': 'C1696103', 'confidence': 1.0}, {'entity': 'pyloric gland metaplasia', 'concept_id': 'C4288813', 'confidence': 1.0}, {'entity': 'colitis', 'concept_id': 'C0009319', 'confidence': 1.0}, {'entity': 'end-associated injury', 'concept_id': 'C0552509', 'confidence': 0.6716579794883728}, {'entity': 'mycophenol-associated injury', 'concept_id': 'C0552509', 'confidence': 0.6023857593536377}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'solid organ transplant', 'concept_id': 'C0730400', 'confidence': 1.0}, {'entity': 'recipient', 'concept_id': 'C1709854', 'confidence': 1.0}, {'entity': 'mycophenol-associated injury', 'concept_id': 'C0552509', 'confidence': 0.6023857593536377}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'GVHD', 'concept_id': 'C0018133', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_82",
"caption_rating": "8"
},
{
"": "1006374",
"caption": "Explanation of different nuclear patterns seen on histology slides, including monomorphic nuclei where all nuclei appear similar to each other.",
"image_path": "Wiyo6taYRF4_image_fddb29a4-5c9c-4710-8cbd-42083a9d7743.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Hematopathology', 'Neuropathology', 'Cytopathology']",
"roi_text": "[]",
"noisy_text": " Now, once we have understood the staining pattern of the nuclei, we should also understand what are the different nuclear patterns that we will see on the histology slide. So there are two patterns that are usually described. One is called as monomorphic nuclei. So monomorphic means when all the nuclei, they appear relatively similar to each other. So if the nuclei, they're looking similar to each other, then we will say that the nuclei are monomorphic. And like in this case, you have all the nuclei which are looking",
"corrected_text": " Now, once we have understood the staining pattern of the nuclei, we should also understand what are the different nuclear patterns that we will see on the histology slide. So there are two patterns that are usually described. One is called as monomorphic nuclei. So monomorphic means when all the nuclei, they appear relatively similar to each other. So if the nuclei, they're looking similar to each other, then we will say that the nuclei are monomorphic. And like in this case, you have all the nuclei which are looking",
"med_umls_ids": "[[{'entity': 'Explanation', 'concept_id': 'C0681841', 'confidence': 0.9999998807907104}, {'entity': 'nuclear patterns', 'concept_id': 'C0449774', 'confidence': 0.7514219284057617}, {'entity': 'histology', 'concept_id': 'C0019638', 'confidence': 1.0}, {'entity': 'slides', 'concept_id': 'C0444330', 'confidence': 1.0}, {'entity': 'monomorphic nuclei', 'concept_id': 'C0205649', 'confidence': 0.61530601978302}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1152.0",
"id": "test_83",
"caption_rating": "8"
},
{
"": "1005601",
"caption": "Presence of myxoid stroma and glandular differentiation can be seen in PCCs.",
"image_path": "udoW6VSqsm4_image_9e0a52df-aabf-4f95-91af-6da268169221.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " What neoplasms in the skin do have a myxoid stroma but also the glandular differentiation? PCCs can have... Sometimes they can, yeah. But this one was not connected to the epidermis in any way. No, not at all. And that raises suspicion like maybe this is coming from some other organ. Okay, a metastatic leaf can do that. Yeah, like breast or some... What part of the body are we on? We are acral. Yeah, we are acral. What is a glandular neoplasm in an acral site that can sometimes have a somewhat myxoid stroma? And their neoplasm in acral... I'm not",
"corrected_text": " What neoplasms in the skin do have a myxoid stroma but also the glandular differentiation? PCCs can have... Sometimes they can, yeah. But this one was not connected to the epidermis in any way. No, not at all. And that raises suspicion like maybe this is coming from some other organ. Okay, a metastatic leaf can do that. Yeah, like breast or some... What part of the body are we on? We are acral. Yeah, we are acral. What is a glandular neoplasm in an acral site that can sometimes have a somewhat myxoid stroma? And their neoplasm in acral... I'm not",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'myxoid stroma', 'concept_id': 'C1334857', 'confidence': 0.8506528735160828}, {'entity': 'glandular differentiation', 'concept_id': 'C1711212', 'confidence': 1.0}, {'entity': 'PCCs', 'concept_id': 'C1454906', 'confidence': 0.6863886713981628}], [{'entity': 'Suspicion', 'concept_id': 'C0242114', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'organ', 'concept_id': 'C0178784', 'confidence': 1.0}, {'entity': 'epidermis', 'concept_id': 'C0014520', 'confidence': 1.0}], [{'entity': 'Metastatic lesion', 'concept_id': 'C1513183', 'confidence': 1.0}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'breast', 'concept_id': 'C0006141', 'confidence': 1.0}, {'entity': 'organs', 'concept_id': 'C0178784', 'confidence': 1.0}], [{'entity': 'glandular neoplasms', 'concept_id': 'C0205854', 'confidence': 1.0}, {'entity': 'acral sites', 'concept_id': 'C0205145', 'confidence': 0.7343063950538635}, {'entity': 'myxoid stroma', 'concept_id': 'C1334857', 'confidence': 0.8506528735160828}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_84",
"caption_rating": "8"
},
{
"": "1006617",
"caption": "The nuclei of the stratified cells reach the middle third and maintain polarity, with no prominent nuclei or cribriform/micropapillary formation.",
"image_path": "r7OA0Trj5hQ_image_c4c5f8b8-f86e-4f9c-b7b3-ddf9060eee55.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Stratified nuclei reaching middle third', 'Nuclei traveling in one direction', 'Maintained polarity', 'No prominent nuclei', 'No cribriform/micropapillary formation', 'Stratified nuclei reaching middle third', 'Nuclei traveling in one direction', 'Maintained polarity', 'No prominent nuclei', 'No cribriform/micropapillary formation']",
"noisy_text": " And this stratified nuclei reach the middle third. They are not touching the upper top of the apical membrane. They are reaching the middle third predominantly. Okay, that is one important point. And other one is, look at this nuclei. They are all traveling in one direction. So the polarity is maintained. Okay, so those two points are very important. And the third one is no prominent nuclei. Nuclei are not prominent. And the fourth point is, no cribriformic or micropapillary formation. So the predominant features you see here is the maintained polarity, nuclei reaching",
"corrected_text": " And this stratified nuclei reach the middle third. They are not touching the upper top of the apical membrane. They are reaching the middle third predominantly. Okay, that is one important point. And other one is, look at this nuclei. They are all traveling in one direction. So the polarity is maintained. Okay, so those two points are very important. And the third one is no prominent nuclei. Nuclei are not prominent. And the fourth point is, no cribriform pattern or micropapillary formation. So the predominant features you see here is the maintained polarity, nuclei reaching",
"med_umls_ids": "[[{'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'stratified cells', 'concept_id': 'C0205363', 'confidence': 0.7615563869476318}, {'entity': 'middle', 'concept_id': 'C0227972', 'confidence': 1.0}, {'entity': 'polarity', 'concept_id': 'C0596963', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'cribriform/micropapillary formation', 'concept_id': 'C1621425', 'confidence': 0.5390191674232483}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_85",
"caption_rating": "9"
},
{
"": "1006627",
"caption": "Inflammatory bowel disease can cause loss of organized tubular architecture and abnormal gland growth.",
"image_path": "sDFjOtMAYrk_image_e0850284-dc39-471f-9cff-c2943a16ca3f.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "[]",
"noisy_text": " cytosis that includes some eosinophils. So, the other trich I like to use, and I heard this from Dr. Appelman one time when he was lecturing, and he described crypt architecture in cases with inflammatory bowel disease, you no longer have that nice organized test tubes in a rack kind of architecture. The glands start to look like anything they want to look like. Rabbits, monkeys, the face of Jesus, whatever, except for test tubes on a rack. And the other thing is, sometimes you'll see them instead of growing down, they'll grow sideways. So, that's very apparent, very abnormal. So, I would say this is great evidence of chronicity, good architectural distortion. What other features besides architecture can you see in cases where there's some chronicity, albeit nonspecific findings? I mean, nothing is specific in chronic inflammatory colonic pathology,",
"corrected_text": " cytosis that includes some eosinophils. So, the other trich I like to use, and I heard this from Dr. Appelman one time when he was lecturing, and he described crypt architecture in cases with inflammatory bowel disease, you no longer have that nice organized tubular architecture. The glands start to look like anything they want to look like. Rabbits, monkeys, the face of Jesus, whatever, except for test tubes on a rack. And the other thing is, sometimes you'll see them instead of growing down, they'll grow sideways. So, that's very apparent, very abnormal. So, I would say this is great evidence of chronicity, good architectural distortion. What other features besides architecture can you see in cases where there's some chronicity, albeit nonspecific findings? I mean, nothing is specific in chronic inflammatory colonic pathology,",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'cytosis', 'concept_id': 'C0010843', 'confidence': 0.7890887260437012}], [{'entity': 'Inflammatory bowel disease', 'concept_id': 'C0021390', 'confidence': 1.0}, {'entity': 'loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'tubular', 'concept_id': 'C0151747', 'confidence': 1.0}, {'entity': 'architecture', 'concept_id': 'C0003737', 'confidence': 1.0}, {'entity': 'abnormal', 'concept_id': 'C0205161', 'confidence': 1.0}, {'entity': 'growth', 'concept_id': 'C0018270', 'confidence': 1.0}], [{'entity': 'Chronicity', 'concept_id': 'C0547045', 'confidence': 1.0}, {'entity': 'architectural distortion', 'concept_id': 'C2826609', 'confidence': 1.0}, {'entity': 'nonspecific', 'concept_id': 'C0750540', 'confidence': 1.0}, {'entity': 'findings', 'concept_id': 'C2607943', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_86",
"caption_rating": "7"
},
{
"": "1005466",
"caption": "Presence of basal cells at the periphery indicates that the tumor is not invasive.",
"image_path": "iklRyY1nBIE_image_943dc3a5-3548-4b93-8b05-23755f6f6e2c.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['basal cells at the periphery', 'enlarged nuclei', 'intraductal carcinoma of the prostate', 'adjacent invasive tumor', 'previously benign gland', 'basal cells at the periphery', 'enlarged nuclei', 'intraductal carcinoma of the prostate', 'adjacent invasive tumor', 'previously benign gland']",
"noisy_text": " Let me show you what the cocktail looks like. Again, this is the pin three, or some call it pin four. You have the P63, you have the hemoglobin cytokeratin, and then you have the racemase, which is the pink chromogen. And as you can see, as I demonstrated on the H&E, basal cells are indeed present. This is too much for high-grade pin. This is basically what is called a solid cribriform kind of pattern, in which over 50% of the lumen is filled by tumor cells. So this is way too much for high-grade pin. But it's not invasive, because you have basal cells at the periphery. And the nuclei are enlarged. These nuclei are about six times the size of normal prostate nuclei. So this case meets the criteria for introductal carcinoma of the prostate. There is an invasive component, which you can see is negative for basal cell markers. But you have the introductal component. And this is a very interesting entity. The vast majority of cases, and I'll show you the corresponding radical prostatectomy specimens in a second, but the vast majority of these so-called introductal carcinoma of the prostate is due to invasion, colonization by adjacent invasive tumor. And it usually occurs in patients that have high-volume tumors. When I show you the corresponding radical prostatectomies, you'll see what I'm talking about. You usually don't have this in patients in their radicals that have 5% prostate cancer or 10% prostate cancer. It's usually patients that have extensive prostate cancer involvement, and the invasive glands basically have nowhere else to go but to colonize adjacent benign glands. And I'll demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues,",
"corrected_text": " Let me show you what the cocktail looks like. Again, this is the pin three, or some call it pin four. You have the P63, you have the hemoglobin cytokeratin, and then you have the racemase, which is the AMACR. And as you can see, as I demonstrated on the H&E, basal cells are indeed present. This is too much for high-grade pin. This is basically what is called a solid cribriform kind of pattern, in which over 50% of the lumen is filled by tumor cells. So this is way too much for high-grade pin. But it's not invasive, because you have basal cells at the periphery. And the nuclei are enlarged. These nuclei are about six times the size of normal prostate nuclei. So this case meets the criteria for intraductal carcinoma of the prostate. There is an invasive component, which you can see is negative for basal cell markers. But you have the intraductal component. And this is a very interesting entity. The vast majority of cases, and I'll show you the corresponding radical prostatectomy specimens in a second, but the vast majority of these so-called intraductal carcinoma of the prostate is due to invasion, colonization by adjacent invasive tumor. And it usually occurs in patients that have high-volume tumors. When I show you the corresponding radical prostatectomies, you'll see what I'm talking about. You usually don't have this in patients in their radicals that have 5% prostate cancer or 10% prostate cancer. It's usually patients that have extensive prostate cancer involvement, and the invasive glands basically have nowhere else to go but to colonize adjacent benign glands. And I'demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues,",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'cocktail', 'concept_id': 'C0678420', 'confidence': 1.0}, {'entity': 'markers', 'concept_id': 'C0181734', 'confidence': 0.890313982963562}, {'entity': 'intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate diagnosis', 'concept_id': 'C0011900', 'confidence': 0.7927443981170654}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'basal cells', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}], [{'entity': 'Enlarged nuclei', 'concept_id': 'C4013177', 'confidence': 0.7774685621261597}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'normal', 'concept_id': 'C0205307', 'confidence': 1.0}], [{'entity': 'Intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'invasion', 'concept_id': 'C1269955', 'confidence': 1.0}, {'entity': 'colonization', 'concept_id': 'C4289767', 'confidence': 1.0}, {'entity': 'adjacent', 'concept_id': 'C0205117', 'confidence': 1.0}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}], [{'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'benign gland', 'concept_id': 'C0205183', 'confidence': 0.7986565828323364}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_87",
"caption_rating": "8"
},
{
"": "1008590",
"caption": "Lamina propria edema and muscularis mucosa coming into the lamina propria are criteria for chemical gastritis.",
"image_path": "r7OA0Trj5hQ_image_e4ca3b4b-74d6-408a-8711-0e8944691e10.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['lamina propria edema', 'muscularis mucosa', 'neutrophils', 'eosinophils', 'stomach', 'esophagus', 'enteritis', 'colitis', 'lamina propria edema', 'muscularis mucosa', 'neutrophils', 'eosinophils', 'stomach', 'esophagus', 'enteritis', 'colitis']",
"noisy_text": " Lamina propria edema and muscularis mucosa coming into the lamina propria. These are the three criterias. When you see it in the anterobiopsy, think of chemical gastritis that can be seen in biliary reflux or NSAID use. Lot of inflammation results. Remember I told you if you see more than five neutrophils, more than five eosinophils sitting in the lamina propria or more than 15 eosinophils per high power field, that is a eosinophilic gastritis, if it is from the stomach. If it is esophagus, it is eosinophilic esophagitis, eosinophilic entritis, eosinophilic colitis. So eosinophilic",
"corrected_text": " Lamina propria edema and muscularis mucosa coming into the lamina propria. These are the three criterias. When you see it in the antral biopsy, think of chemical gastritis that can be seen in biliary reflux or NSAID use. Lot of inflammation results. Remember I told you if you see more than five neutrophils, more than five eosinophils sitting in the lamina propria or more than 15 or more eosinophils per high power field, that is a eosinophilic gastritis, if it is from the stomach. If it is esophagus, it is eosinophilic esophagitis, eosinophilic enteritis, eosinophilic colitis. So eosinophilic",
"med_umls_ids": "[[{'entity': 'Lamina propria edema', 'concept_id': 'C1179187', 'confidence': 0.7593827247619629}, {'entity': 'muscularis mucosa', 'concept_id': 'C0225357', 'confidence': 0.9999998807907104}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'criteria', 'concept_id': 'C0243161', 'confidence': 0.9999998807907104}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}], [{'entity': 'Inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}], [{'entity': 'Eosinophilic gastritis', 'concept_id': 'C0267154', 'confidence': 1.0}, {'entity': 'diagnosed', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}], [{'entity': 'Eosinophilic esophagitis', 'concept_id': 'C0341106', 'confidence': 0.9999999403953552}, {'entity': 'eosinophilic enteritis', 'concept_id': 'C1262481', 'confidence': 1.0}, {'entity': 'eosinophilic colitis', 'concept_id': 'C0267448', 'confidence': 1.0}, {'entity': 'diagnoses', 'concept_id': 'C0011900', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_88",
"caption_rating": "8"
},
{
"": "1005876",
"caption": "Sarcoidosis can have various clinical manifestations, including cutaneous Crohn's disease.",
"image_path": "udoW6VSqsm4_image_37553080-6eed-4b96-875a-23582869a2dc.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "[\"cutaneous Crohn's\", 'sarcoidosis']",
"noisy_text": " So, there are a lot of clinical manifestations of sarcoidosis. So, yeah, this is a beautiful example of that. Caneous Crohn's, that's why I was going to ask. Caneous Crohn's can look sort of like this, yeah. That would be the differential also. So, yeah, you think about that. Usually, you know, Balfour's and Rosenthal. Usually not quite this degree like you see here. This is really a great example of real sarcoid. But, obviously, it's a clinical pathologic correlative diagnosis. Okay, this is",
"corrected_text": " So, there are a lot of clinical manifestations of sarcoidosis. So, yeah, this is a beautiful example of that. cutaneous Crohn's, that's why I was going to ask. cutaneous Crohn's can look sort of like this, yeah. That would be the differential also. So, yeah, you think about that. Usually, you know, Balfour's and Rosenthal. Usually not quite this degree like you see here. This is really a great example of real sarcoid. But, obviously, it's a clinical pathologic correlative diagnosis. Okay, this is",
"med_umls_ids": "[[{'entity': 'Sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'clinical manifestations', 'concept_id': 'C4231046', 'confidence': 0.9626281261444092}, {'entity': \"cutaneous Crohn's disease\", 'concept_id': 'C0010346', 'confidence': 0.8764320611953735}], [{'entity': \"Cutaneous Crohn's disease\", 'concept_id': 'C0010346', 'confidence': 0.8764320611953735}, {'entity': 'differential diagnosis', 'concept_id': 'C0011906', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_89",
"caption_rating": "8"
},
{
"": "1006373",
"caption": "Hemocyanin is present within the histiocytes.",
"image_path": "8S4LeiO6Bbk_image_96305b37-895c-472d-81ed-c73675997c03.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['lipid vacuoles', 'multinucleated histiocytes', 'ringed siderophages', 'pigmented histiocytes', 'hemocyanin']",
"noisy_text": " large histiocytes containing lipid. Some of them are multi-nucleated and some of these are actually ringed siderophages. So we see large multi-nucleated histiocytes with a ring of nuclei and they contain not only lipid vacuoles but hemocentaurant. And these are particularly common in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes as suspected is hemocentaurant. If you notice, it's got kind of that golden brown color. If you had a sub-stage condenser or a fine focus knob, you would see that it's somewhat refractile, but unfortunately, we can't use that particular tool when we're looking at scanned images.",
"corrected_text": " large histiocytes containing lipid. Some of them are multinucleated and some of these are actually ringed siderophages. So we see large multinucleated histiocytes with a ring of nuclei and they contain not only lipid vacuoles but hemosiderin. And these are particularly common in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes as suspected is hemosiderin. If you notice, it's got kind of that golden brown color. If you had a sub-stage condenser or a fine focus knob, you would see that it's somewhat refractile, but unfortunately, we can't use that particular tool when we're looking at scanned images.",
"med_umls_ids": "[[{'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'lipid', 'concept_id': 'C0023779', 'confidence': 1.0}, {'entity': 'multinucleated', 'concept_id': 'C0333740', 'confidence': 1.0}, {'entity': 'ringed', 'concept_id': 'C0325501', 'confidence': 0.77345871925354}, {'entity': 'siderophages', 'concept_id': 'C1136253', 'confidence': 0.7251443266868591}], [{'entity': 'Hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}], [{'entity': 'Pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_90",
"caption_rating": "7"
},
{
"": "1005408",
"caption": "The lesion likely started as a benign leiomyoma, but developed a sarcomatous area within it, becoming a leiomyosarcoma.",
"image_path": "LlPaENuqzVQ_image_b98d48ab-c56c-4519-90e3-490bee88c0a3.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['Benign leiomyoma', 'Leiomyosarcoma with zones of pleomorphism and spindle cells']",
"noisy_text": " So this lesion probably started off as a benign lyomyoma. So I think in some areas it doesn't look very atypical. Right there, that's pretty typical appearing lyomyoma. Other areas though, you see there's zones of pleomorphism and some spindle-shaped cells that are quite very incised and shaped. There's quite a few mitoses. So this is an example of a lyomyosarcoma that probably started off as a lyomyoma and just developed a sarcomatous area within it. So these are, they're kind of a different animal than just",
"corrected_text": " So this lesion probably started off as a benign leiomyoma. So I think in some areas it doesn't look very atypical. Right there, that's pretty typical appearing leiomyoma. Other areas though, you see there's zones of pleomorphism and some spindle-shaped cells that are quite very incised and shaped. There's quite a few mitoses. So this is an example of a leiomyosarcoma that probably started off as a leiomyoma and just developed a sarcomatous area within it. So these are, they're kind of a different animal than just",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'benign leiomyoma', 'concept_id': 'C0023267', 'confidence': 0.9082092046737671}, {'entity': 'sarcomatous area', 'concept_id': 'C0334513', 'confidence': 0.7075703144073486}, {'entity': 'leiomyosarcoma', 'concept_id': 'C0023269', 'confidence': 1.0}], [{'entity': 'zones', 'concept_id': 'C1710706', 'confidence': 0.8182461857795715}, {'entity': 'pleomorphism', 'concept_id': 'C0032219', 'confidence': 1.0}, {'entity': 'spindle cells', 'concept_id': 'C0682540', 'confidence': 1.0}, {'entity': 'mitoses', 'concept_id': 'C0026255', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_91",
"caption_rating": "9"
},
{
"": "1008397",
"caption": "The finding of pyloric gland metaplasia can be difficult to spot in cases of inflammatory bowel disease.",
"image_path": "sDFjOtMAYrk_image_937f5af8-c118-413b-9509-acbdde06cba9.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['pyloric gland metaplasia', 'inflammatory bowel disease']",
"noisy_text": " other like, collagenous colitis, other types of inflammatory processes? Yes. So, the other finding would be pyloric gland metaplasia, which I find a little bit more difficult to spot if you're not really looking for it because the glands kind of blend in to the, you know, the background colonic mucosa. But once you learn to look for it, you'll find and we'll see a little bit of it further down the road. So, this is a case of inflammatory bowel disease. And this is what I like to compare everything to in order to avoid labeling patients with IBD who don't have IBD and who should be receiving other treatments other than immune suppression. So, just have this, you know,",
"corrected_text": " other like, collagenous colitis, other types of inflammatory processes? Yes. So, the other finding would be pyloric gland metaplasia, which I find a little bit more difficult to spot if you're not really looking for it because the glands kind of blend in to the, you know, the background colonic mucosa. But once you learn to look for it, you'll find and we'll see a little bit of it further down the road. So, this is a case of inflammatory bowel disease. And this is what I like to compare everything to in order to avoid labeling patients with IBD who don't have IBD and who should be receiving other treatments other than immune suppression. So, just have this, you know,",
"med_umls_ids": "[[{'entity': 'finding', 'concept_id': 'C0037088', 'confidence': 1.0}, {'entity': 'pyloric gland metaplasia', 'concept_id': 'C4288813', 'confidence': 1.0}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'inflammatory bowel disease', 'concept_id': 'C0021390', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_92",
"caption_rating": "8"
},
{
"": "1004665",
"caption": "The patient had a teratoma component that was not eliminated by therapy, which extended to the prostate and bladder.",
"image_path": "iklRyY1nBIE_image_a46f7ff7-e57e-4483-9fa1-fa24f07a41d7.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['teratoma component', 'prostate', 'bladder', 'positive digital rectal examination', 'elevated PSA level']",
"noisy_text": " tumor, got therapy, and unfortunately, had the teratoma. And this happens a lot. The therapy took care of the other embryonic, carcinoma, yolk cell tumor components, semi-normal components, et cetera, but the teratoma component stayed behind. So this is the margin that is always negative. As you can see, there is tumor present. So the teratoma extended to this area also. So this was a diffuse involvement of the prostate. There was also some bladder involvement by this tumor. So this was bad news for this gentleman. So the last case I'm going to share before we go to the Q&A is case number 10. Case number 10 is a 58-year-old gentleman with a positive digital rectal examination and elevated PSA level. So right off the bat, you can appreciate that this is an",
"corrected_text": " tumor, got therapy, and unfortunately, had the teratoma. And this happens a lot. The therapy took care of the other embryonic, carcinoma, yolk cell tumor components, normal components, et cetera, but the teratoma component stayed behind. So this is the margin that is always negative. As you can see, there is tumor present. So the teratoma extended to this area also. So this was a diffuse involvement of the prostate. There was also some bladder involvement by this tumor. So this was bad news for this gentleman. So the last case I'm going to share before we go to the Q&A is case number 10. Case number 10 is a 58-year-old gentleman with a positive digital rectal examination and elevated PSA level. So right off the bat, you can appreciate that this is an",
"med_umls_ids": "[[{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'teratoma', 'concept_id': 'C0039538', 'confidence': 1.0}, {'entity': 'component', 'concept_id': 'C0449432', 'confidence': 1.0}, {'entity': 'therapy', 'concept_id': 'C0039798', 'confidence': 0.9999999403953552}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'bladder', 'concept_id': 'C0005682', 'confidence': 1.0}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'digital rectal examination', 'concept_id': 'C0199900', 'confidence': 1.0}, {'entity': 'elevated', 'concept_id': 'C0205250', 'confidence': 0.9999999403953552}, {'entity': 'PSA', 'concept_id': 'C0138741', 'confidence': 1.0}, {'entity': 'level', 'concept_id': 'C0441889', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_93",
"caption_rating": "8"
},
{
"": "1005409",
"caption": "There are zones of pleomorphism and spindle cells with many mitoses.",
"image_path": "LlPaENuqzVQ_image_b98d48ab-c56c-4519-90e3-490bee88c0a3.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['Benign leiomyoma', 'Leiomyosarcoma with zones of pleomorphism and spindle cells']",
"noisy_text": " So this lesion probably started off as a benign lyomyoma. So I think in some areas it doesn't look very atypical. Right there, that's pretty typical appearing lyomyoma. Other areas though, you see there's zones of pleomorphism and some spindle-shaped cells that are quite very incised and shaped. There's quite a few mitoses. So this is an example of a lyomyosarcoma that probably started off as a lyomyoma and just developed a sarcomatous area within it. So these are, they're kind of a different animal than just",
"corrected_text": " So this lesion probably started off as a benign leiomyoma. So I think in some areas it doesn't look very atypical. Right there, that's pretty typical appearing leiomyoma. Other areas though, you see there's zones of pleomorphism and some spindle-shaped cells that are quite very incised and shaped. There's quite a few mitoses. So this is an example of a leiomyosarcoma that probably started off as a leiomyoma and just developed a sarcomatous area within it. So these are, they're kind of a different animal than just",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'benign leiomyoma', 'concept_id': 'C0023267', 'confidence': 0.9082092046737671}, {'entity': 'sarcomatous area', 'concept_id': 'C0334513', 'confidence': 0.7075703144073486}, {'entity': 'leiomyosarcoma', 'concept_id': 'C0023269', 'confidence': 1.0}], [{'entity': 'zones', 'concept_id': 'C1710706', 'confidence': 0.8182461857795715}, {'entity': 'pleomorphism', 'concept_id': 'C0032219', 'confidence': 1.0}, {'entity': 'spindle cells', 'concept_id': 'C0682540', 'confidence': 1.0}, {'entity': 'mitoses', 'concept_id': 'C0026255', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_94",
"caption_rating": "8"
},
{
"": "1007452",
"caption": "Metaplasia of the gastric mucosa in the body of the stomach.",
"image_path": "r7OA0Trj5hQ_image_ea289d78-ddcf-4e88-889c-f81b330d7002.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['body of the stomach']",
"noisy_text": " metaplasia of the gastric mucosa. Here the history is this biopsy is taken from the body of the stomach. In the body of the stomach, you have to see a lot of fried eggs. These are all the peritoneal cells in addition to mucincycletine cells and chief cells. These are the peritoneal cells. When you don't see the peritoneal cells in the gastric fundic mucosa or gastric corpus mucosa, then you have to call it as pyloric metaplasia. This is very, very important because you see it in autoimmune gastritis. Sometimes the",
"corrected_text": " metaplasia of the gastric mucosa. Here the history is this biopsy is taken from the body of the stomach. In the body of the stomach, you have to see a lot of fried eggs. These are all the peritoneal cells in addition to mucincycletine cells and chief cells. These are the peritoneal cells. When you don't see the peritoneal cells in the gastric fundic mucosa or gastric corpus mucosa, then you have to call it as pyloric metaplasia. This is very, very important because you see it in autoimmune gastritis. Sometimes the",
"med_umls_ids": "[[{'entity': 'Metaplasia', 'concept_id': 'C0025568', 'confidence': 1.0}, {'entity': 'gastric mucosa', 'concept_id': 'C0017136', 'confidence': 1.0}, {'entity': 'body', 'concept_id': 'C0227230', 'confidence': 1.0}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'peritoneal cells', 'concept_id': 'C0031153', 'confidence': 0.7749612331390381}, {'entity': 'mucincycletine cells', 'concept_id': 'C0007586', 'confidence': 0.6177586317062378}, {'entity': 'chief cells', 'concept_id': 'C1516470', 'confidence': 1.0}], [{'entity': 'Absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'peritoneal cells', 'concept_id': 'C0031153', 'confidence': 0.7749612331390381}, {'entity': 'gastric fundic mucosa', 'concept_id': 'C0017136', 'confidence': 0.8429272770881653}, {'entity': 'gastric corpus mucosa', 'concept_id': 'C0735811', 'confidence': 0.9813486337661743}, {'entity': 'pyloric metaplasia', 'concept_id': 'C4288813', 'confidence': 0.8951747417449951}], [{'entity': 'Pyloric metaplasia', 'concept_id': 'C4288813', 'confidence': 0.8951747417449951}, {'entity': 'autoimmune gastritis', 'concept_id': 'C3887639', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_95",
"caption_rating": "8"
},
{
"": "1008507",
"caption": "The presence of more than five neutrophils or more than 15 eosinophils per high power field in the lamina propria is indicative of eosinophilic gastritis, esophagitis, enteritis, or colitis.",
"image_path": "r7OA0Trj5hQ_image_650589f2-51ab-4da8-b7f0-19ff3670641c.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Cryptitis', 'Crypt abscess', 'Variation in gland size, shape, and distribution.', 'Cryptitis', 'Crypt abscess', 'Variation in gland size, shape, and distribution.']",
"noisy_text": " Remember I told you if you see more than five neutrophils, more than five eosinophils sitting in the lamina propria or more than 15 eosinophils per high power field, that is a eosinophilic gastritis, if it is from the stomach. If it is esophagus, it is eosinophilic esophagitis, eosinophilic entritis, eosinophilic colitis. So eosinophilic gastroenteritis. Here it is a cryptitis and cryptopsis. And the glands are also pushed well apart. The glands are showing variation in size, shape, distribution. So this is chronic colitis with activity.",
"corrected_text": " Remember I told you if you see more than five neutrophils, more than five eosinophils sitting in the lamina propria or more than 15 eosinophils per high power field, that is a eosinophilic gastritis, if it is from the stomach. If it is esophagus, it is eosinophilic esophagitis, eosinophilic enteritis, eosinophilic colitis. So eosinophilic gastroenteritis. Here it is a cryptitis and crypt abscess. And the glands are also pushed well apart. The glands are showing variation in size, shape, distribution. So this is chronic colitis with activity.",
"med_umls_ids": "[[{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'eosinophilic gastritis', 'concept_id': 'C0267154', 'confidence': 1.0}, {'entity': 'esophagitis', 'concept_id': 'C0014868', 'confidence': 1.0}, {'entity': 'enteritis', 'concept_id': 'C0014335', 'confidence': 1.0}, {'entity': 'colitis', 'concept_id': 'C0009319', 'confidence': 1.0}], [{'entity': 'cryptitis', 'concept_id': 'C1394254', 'confidence': 0.9999998807907104}, {'entity': 'crypt', 'concept_id': 'C1880192', 'confidence': 1.0}, {'entity': 'abscess', 'concept_id': 'C0000833', 'confidence': 1.0}, {'entity': 'inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}, {'entity': 'area', 'concept_id': 'C0017446', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_96",
"caption_rating": "9"
},
{
"": "1005719",
"caption": "There are several melanocytes present, some forming nests and extending into the upper portions of the matrix in a pagetoid pattern.",
"image_path": "8S4LeiO6Bbk_image_58ea89e7-01d3-42bd-ae6c-2fd10813005a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['nail bed', 'matrix epithelium', 'melanocytes forming nests', 'pagetoid pattern', 'basal layer of the matrix', 'upper portions of the matrix', 'nail bed', 'matrix epithelium', 'melanocytes forming nests', 'pagetoid pattern', 'basal layer of the matrix', 'upper portions of the matrix']",
"noisy_text": " we've got nail bed and matricle epithelium. I believe this must be some nail fold, a portion of the nail fold, and then in the bottom piece of tissue in these sections we actually have matricle epithelium and you can see the rete or somewhat hyperplastic. And on higher power examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matricle epithelium in the matricle layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that",
"corrected_text": " we've got nail bed and matrix epithelium. I believe this must be some nail fold, a portion of the nail fold, and then in the bottom piece of tissue in these sections we actually have matrix epithelium and you can see the rete or somewhat hyperplastic. And on higher power examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matrix epithelium in the matrix layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that",
"med_umls_ids": "[[{'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'nail', 'concept_id': 'C0027342', 'confidence': 1.0}, {'entity': 'matrix epithelium', 'concept_id': 'C0014609', 'confidence': 0.7584323883056641}], [{'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'nests', 'concept_id': 'C0035253', 'confidence': 0.7275967001914978}, {'entity': 'upper portions', 'concept_id': 'C0449719', 'confidence': 0.6251541972160339}, {'entity': 'matrix', 'concept_id': 'C0331858', 'confidence': 1.0}, {'entity': 'pagetoid', 'concept_id': 'C1518847', 'confidence': 0.8801172375679016}, {'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}], [{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'matrix layer', 'concept_id': 'C0331858', 'confidence': 0.71736741065979}, {'entity': 'suspicious', 'concept_id': 'C0750493', 'confidence': 1.0}, {'entity': 'melanoma', 'concept_id': 'C0025202', 'confidence': 1.0}, {'entity': 'in situ', 'concept_id': 'C0444498', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_97",
"caption_rating": "9"
},
{
"": "1004773",
"caption": "Histopathological description of a tumor with big collagen rich rosettes and a prominent round cell appearance around the edge of the rim of the nodules, resembling small round blue cells of a neuroblastoma.",
"image_path": "QDb68_G1HR4_image_7cea0913-e476-4f9a-8b1b-a61bc5b81a7b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Big collagen rich rosettes', 'Prominent round cell appearance around the edge of the rim of the nodules', 'Small round blue cells of a neuroblastoma', 'Big collagen rich rosettes', 'Prominent round cell appearance around the edge of the rim of the nodules', 'Small round blue cells of a neuroblastoma']",
"noisy_text": " It has also big collagen rich rosettes like this but it has a much more prominent round cell appearance around the edge of the rim of the nodules are very like small round blue cell almost look a little bit like the small round blue cells of a neuroblastoma which is why it's named that way but I've definitely seen pathologists have trouble telling those two apart telling a hyalinizing spindle cell tumor with giant rosettes. This tumor we're looking at here a variation of low-grade fibromyxoid sarcoma I've seen people get that confused with the neuroblastoma-like variant of schwannoma and the difference is important because the schwannoma is even though the name sounds kind of scary is actually benign it has a small round blue cell appearance but it's totally benign variation of schwannoma. S100 should easily solve that problem because S100 would be negative here in low-grade fibromyxoid sarcoma and",
"corrected_text": " It has also big collagen rich rosettes like this but it has a much more prominent round cell appearance around the edge of the rim of the nodules are very like small round blue cell almost look a little bit like the small round blue cells of a neuroblastoma which is why it's named that way but I've definitely seen pathologists have trouble telling those two apart telling a hyalinizing spindle cell tumor with giant rosettes. This tumor we're looking at here a variation of low-grade fibromyxoid sarcoma I've seen people get that confused with the neuroblastoma-like variant of schwannoma and the difference is important because the schwannoma is even though the name sounds kind of scary is actually benign it has a small round blue cell appearance but it's totally benign variation of schwannoma. S100 should easily solve that problem because S100 would be negative here in low-grade fibromyxoid sarcoma and",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'rosettes', 'concept_id': 'C0035863', 'confidence': 0.8847858905792236}, {'entity': 'round cell', 'concept_id': 'C0487470', 'confidence': 1.0}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'edge', 'concept_id': 'C0205154', 'confidence': 1.0}, {'entity': 'rim', 'concept_id': 'C1308727', 'confidence': 1.0}, {'entity': 'nodules', 'concept_id': 'C0028259', 'confidence': 1.0}, {'entity': 'neuroblastoma', 'concept_id': 'C0027819', 'confidence': 1.0}], [{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'variation', 'concept_id': 'C0205419', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'neuroblastoma-like variant of', 'concept_id': 'C1419295', 'confidence': 0.6589864492416382}, {'entity': 'schwannoma', 'concept_id': 'C0027809', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_98",
"caption_rating": "8"
},
{
"": "1005630",
"caption": "Special stains such as Prussian blue or Fontana-Masson can be used to confirm the presence of hemocyanin or melanin pigment.",
"image_path": "8S4LeiO6Bbk_image_86c69d80-19b3-425b-a70b-4ffd6a5700ff.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Pigmented histiocytes with hemocyanin pigment', 'Extravasated erythrocytes', 'Size of particles within histiocytes', 'Pigmented histiocytes with hemocyanin pigment', 'Extravasated erythrocytes', 'Size of particles within histiocytes']",
"noisy_text": " in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes as suspected is hemocentaurant. If you notice, it's got kind of that golden brown color. If you had a sub-stage condenser or a fine focus knob, you would see that it's somewhat refractile, but unfortunately, we can't use that particular tool when we're looking at scanned images. But one clue to the fact that we're dealing with hemocentaurant rather than melanin, not only is the presence of extravasated erythrocytes, but if you look at the size of the particles within the histiocytes, they're markedly variable. So the hemocentaurant is of course a breakdown product of the RBCs. And you can see that we've got small granules next to very large, chunky granules. Melanin pigment on the other hand, which of course can be found in melanophages or histiocytes containing the particles, the melanin granules tend to be more uniform in size. And of course, one can always do special stains, an iron stain, such as Prussian blue or pearls for hemocentaurant and a Fontanumus song stain for melanin pigment. So in any case, getting back to the to the lesion in question, we've got a lot of hemocentaurant-laden histiocytes here. We've also got, in other areas, fascicles, kind of randomly oriented of histiocytes and fibrocytes with oval",
"corrected_text": " in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes as suspected is hemocyanin. If you notice, it's got kind of that golden brown color. If you had a sub-stage condenser or a fine focus knob, you would see that it's somewhat refractile, but unfortunately, we can't use that particular tool when we're looking at scanned images. But one clue to the fact that we're dealing with hemocyanin rather than melanin, not only is the presence of extravasated erythrocytes, but if you look at the size of the particles within the histiocytes, they're markedly variable. So the hemocyanin is of course a breakdown product of the RBCs. And you can see that we've got small granules next to very large, chunky granules. Melanin pigment on the other hand, which of course can be found in melanophages or histiocytes containing the particles, the melanin granules tend to be more uniform in size. And of course, one can always do special stains, an iron stain, such as Prussian blue or pearls for hemocyanin and a Fontana-Masson stain for melanin pigment. So in any case, getting back to the to the lesion in question, we've got a lot of hemocyanin-laden histiocytes here. We've also got, in other areas, fascicles, kind of randomly oriented of histiocytes and fibrocytes with oval",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'pigment', 'concept_id': 'C0031911', 'confidence': 1.0}, {'entity': 'breakdown', 'concept_id': 'C0699900', 'confidence': 0.9999999403953552}, {'entity': 'product', 'concept_id': 'C1254351', 'confidence': 1.0}, {'entity': 'RBCs', 'concept_id': 'C0014792', 'confidence': 1.0}], [{'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'particles', 'concept_id': 'C0597177', 'confidence': 1.0}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'variable', 'concept_id': 'C0439828', 'confidence': 1.0}], [{'entity': 'Melanin', 'concept_id': 'C0025196', 'confidence': 1.0}, {'entity': 'pigment', 'concept_id': 'C0031911', 'confidence': 1.0}, {'entity': 'uniform', 'concept_id': 'C0205375', 'confidence': 1.0}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}], [{'entity': 'Special stains', 'concept_id': 'C0038128', 'confidence': 0.7105166912078857}, {'entity': 'Prussian blue', 'concept_id': 'C0060234', 'confidence': 1.0}, {'entity': 'Fontana-Masson', 'concept_id': 'C0060631', 'confidence': 0.9090515375137329}, {'entity': 'confirm', 'concept_id': 'C0521093', 'confidence': 1.0}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}, {'entity': 'pigment', 'concept_id': 'C0031911', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_99",
"caption_rating": "8"
},
{
"": "1005211",
"caption": "The infected histiocytes contain round organisms at the periphery that are about one to two microns in size.",
"image_path": "hoV-JkD6Wb0_image_653124da-8816-48ca-93a4-468df20be9f0.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['cytoplasm', 'organisms', 'infected histiocytes', 'large histiocytes']",
"noisy_text": " we can see that we actually have very large histiocytes. We've cleared out cytoplasm and with a little effort, one could see that there were organisms present within the cytoplasm of these histiocytes producing so-called parasitized histiocytes. And the organisms are very small, one to two microns. And we can use our erythrocyte here as kind of a ruler. Most erythrocytes and lymphocytes have nuclei that have diameters about five to six microns. And so you can see that these round organisms at the periphery of the histiocytes are about one to two microns. And as you'll see in a subsequent slide, when you see parasitized histiocytes with organisms of this size in",
"corrected_text": " we can see that we actually have very large histiocytes. We've cleared out cytoplasm and with a little effort, one could see that there were organisms present within the cytoplasm of these histiocytes producing so-called parasitized histiocytes. And the organisms are very small, one to two microns. And we can use our erythrocyte here as kind of a ruler. Most erythrocytes and lymphocytes have nuclei that have diameters about five to six microns. And so you can see that these round organisms at the periphery of the histiocytes are about one to two microns. And as you'll see in a subsequent slide, when you see parasitized histiocytes with organisms of this size in",
"med_umls_ids": "[[{'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'organisms', 'concept_id': 'C0029235', 'confidence': 0.9999998807907104}, {'entity': 'cytoplasm', 'concept_id': 'C0010834', 'confidence': 1.0}], [{'entity': 'Infected', 'concept_id': 'C0439663', 'confidence': 1.0}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}], [{'entity': 'organisms', 'concept_id': 'C0029235', 'confidence': 0.9999998807907104}, {'entity': 'microns', 'concept_id': 'C0439201', 'confidence': 0.9999999403953552}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}], [{'entity': 'infected', 'concept_id': 'C0439663', 'confidence': 1.0}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'round organisms', 'concept_id': 'C0029235', 'confidence': 0.813967227935791}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'microns', 'concept_id': 'C0439201', 'confidence': 0.9999999403953552}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_100",
"caption_rating": "8"
},
{
"": "1008379",
"caption": "Comparison of granulomas in sarcoidosis and Crohn\u2019s disease.",
"image_path": "sDFjOtMAYrk_image_40f283f5-b3a7-423a-9bde-a1595d53e7ad.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['uveitis with characteristic features', 'granulomas in sarcoidosis and Crohn\u2019s disease', 'uveitis with characteristic features', 'granulomas in sarcoidosis and Crohn\u2019s disease']",
"noisy_text": " patient had sarcoid. So I said, this is probably not IBD, clinicians came down, we want to look at the biopsy, of course. It turns out that they went back and talked to the patient. The patient has a history of uveitis with characteristic features that were good for sarcoidosis. Nobody knew about they treated the patient for sarcoid, re-biopsied the patient. And he was fine. There were no more granulomas on multiple repeat biopsies. And now compare those grannies with the grannies in Crohn's. So here's a giant cell right there, but there was a better one right there. So they're like kind of",
"corrected_text": " patient had sarcoid. So I said, this is probably not IBD, clinicians came down, we want to look at the biopsy, of course. It turns out that they went back and talked to the patient. The patient has a history of uveitis with characteristic features that were good for sarcoidosis. Nobody knew about they treated the patient for sarcoid, re-biopsied the patient. And he was fine. There were no more granulomas on multiple repeat biopsies. And now compare those grannies with the grannies in Crohn's. So here's a giant cell right there, but there was a better one right there. So they're like kind of",
"med_umls_ids": "[[{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'suspected', 'concept_id': 'C0332147', 'confidence': 1.0}, {'entity': 'IBD', 'concept_id': 'C0021390', 'confidence': 1.0}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'history', 'concept_id': 'C0019664', 'confidence': 1.0}, {'entity': 'uveitis', 'concept_id': 'C0042164', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'treated', 'concept_id': 'C1522326', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'biopsies', 'concept_id': 'C0005558', 'confidence': 1.0}, {'entity': 'granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}], [{'entity': 'Comparison', 'concept_id': 'C1707455', 'confidence': 1.0}, {'entity': 'granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'Crohn\u2019s disease', 'concept_id': 'C0010346', 'confidence': 0.8916962146759033}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_101",
"caption_rating": "7"
},
{
"": "1004566",
"caption": "Trichodiscoma and perifollicular fibroma are associated lesions that are likely the same as fibrofolliculoma.",
"image_path": "LlPaENuqzVQ_image_696fff92-e7f8-488a-b300-00e801fa69d5.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['Relatively dense fibrous stroma', 'No clefting between the lesion']",
"noisy_text": " and the follicular elements, as well as the perifollicular connective tissue. And it's kind of got this pretty characteristic, it's kind of a relatively dense fibrous stroma. It's not loose and mixoid like the stroma you see around the basal cell carcinoma. Notice that there's no clefting between this, like we see with the basal cell carcinoma. So this is fibrofolliculoma. There's two other lesions that are associated with that. They're really the same lesion. In other words, if you just get mostly fibrous with a little teensy, tiny strand of epithelium left, that's either going to be a trichodyscoma or a perifollicular fibroma. And those are really, they're probably really all the same lesion, just they kind of look a little bit different. So that's kind of important to know that from the",
"corrected_text": " and the follicular elements, as well as the perifollicular connective tissue. And it's kind of got this pretty characteristic, it's kind of a relatively dense fibrous stroma. It's not loose and mixoid like the stroma you see around the basal cell carcinoma. Notice that there's no clefting between this, like we see with the basal cell carcinoma. So this is fibrofolliculoma. There's two other lesions that are associated with that. They're really the same lesion. In other words, if you just get mostly fibrous with a little teensy, tiny strand of epithelium left, that's either going to be a trichodiscoma or a perifollicular fibroma. And those are really, they're probably really all the same lesion, just they kind of look a little bit different. So that's kind of important to know that from the",
"med_umls_ids": "[[{'entity': 'Describes', 'concept_id': 'C1552738', 'confidence': 0.7625278830528259}, {'entity': 'physical characteristics', 'concept_id': 'C1521970', 'confidence': 0.8302092552185059}, {'entity': 'fibrofolliculoma', 'concept_id': 'C0346011', 'confidence': 1.0}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}, {'entity': 'clefting', 'concept_id': 'C4021813', 'confidence': 0.8906428217887878}, {'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}], [{'entity': 'Trichodiscoma', 'concept_id': 'C0346011', 'confidence': 1.0}, {'entity': 'perifollicular fibroma', 'concept_id': 'C1704236', 'confidence': 1.0}, {'entity': 'lesions', 'concept_id': 'C0221198', 'confidence': 1.0}, {'entity': 'fibrofolliculoma', 'concept_id': 'C0346011', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_102",
"caption_rating": "9"
},
{
"": "1009219",
"caption": "Tuberculoid form of leprosy can cause sarcoid granulomatous inflammation.",
"image_path": "udoW6VSqsm4_image_45ba8961-111e-440a-bff9-00b87992409c.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['sarcoid granulomatous inflammation', 'involvement around nerves']",
"noisy_text": " That's the tuberculoid. Yeah, good. The tuberculoid form of leprosy gives you sarcoidal granulomatous inflammation. It's elongated. Very good. That's exactly right. What else can give you sarcoidal granulomatous inflammation? Can I ask a quick question about the sarcoid with the two... The nansins? So, I had a case, I saw a case that looked kind of horizontal, but it was sarcoid. And so, what other ways can you tell? Sometimes it can be difficult, but usually you're going to see involvement around nerves damaged nerves. You're about to get sarcoidal granulomatous inflammation. They always have very high risk inflammatory reactions. They just wipe out the nerves. So, that's helpful. Wasn't",
"corrected_text": " That's the tuberculoid. Yeah, good. The tuberculoid form of leprosy gives you sarcoidal granulomatous inflammation. It's elongated. Very good. That's exactly right. What else can give you sarcoidal granulomatous inflammation? Can I ask a quick question about the sarcoid with the two... The sarcoidosis? So, I had a case, I saw a case that looked kind of horizontal, but it was sarcoid. And so, what other ways can you tell? Sometimes it can be difficult, but usually you're going to see involvement around nerves damaged nerves. You're about to get sarcoidal granulomatous inflammation. They always have very high risk inflammatory reactions. They just wipe out the nerves. So, that's helpful. Wasn't",
"med_umls_ids": "[[{'entity': 'Tuberculoid', 'concept_id': 'C0544783', 'confidence': 0.8459237217903137}, {'entity': 'leprosy', 'concept_id': 'C0023343', 'confidence': 1.0}, {'entity': 'sarcoid', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'granulomatous inflammation', 'concept_id': 'C0553697', 'confidence': 1.0}], [{'entity': 'Involvement', 'concept_id': 'C1314939', 'confidence': 1.0}, {'entity': 'damaged nerves', 'concept_id': 'C3887709', 'confidence': 0.8087002038955688}, {'entity': 'sarcoid', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'granulomatous inflammation', 'concept_id': 'C0553697', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_103",
"caption_rating": "8"
},
{
"": "1007997",
"caption": "Sarcoid granulomatous inflammation can involve damaged nerves and cause high-risk inflammatory reactions.",
"image_path": "udoW6VSqsm4_image_f4ffefb9-a3d1-477d-bc3c-a77762f8b106.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['involvement around nerves', 'sarcoid granulomatous inflammation', 'foreign bodies', 'involvement around nerves', 'sarcoid granulomatous inflammation', 'foreign bodies']",
"noisy_text": " Can I ask a quick question about the sarcoid with the two... The nansins? So, I had a case, I saw a case that looked kind of horizontal, but it was sarcoid. And so, what other ways can you tell? Sometimes it can be difficult, but usually you're going to see involvement around nerves damaged nerves. You're about to get sarcoidal granulomatous inflammation. They always have very high risk inflammatory reactions. They just wipe out the nerves. So, that's helpful. Wasn't it here that we, not long ago, we saw a sarcoidal reaction for a foreign body? Yeah, there are several foreign bodies that can do it. Silica can",
"corrected_text": " Can I ask a quick question about the sarcoid with the two... The non-caseating? So, I had a case, I saw a case that looked kind of horizontal, but it was sarcoid. And so, what other ways can you tell? Sometimes it can be difficult, but usually you're going to see involvement around nerves damaged nerves. You're about to get sarcoid granulomatous inflammation. They always have very high risk inflammatory reactions. They just wipe out the nerves. So, that's helpful. Wasn't it here that we, not long ago, we saw a sarcoid reaction for a foreign body? Yeah, there are several foreign bodies that can do it. Silica can",
"med_umls_ids": "[[{'entity': 'Sarcoid', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'granulomatous inflammation', 'concept_id': 'C0553697', 'confidence': 1.0}, {'entity': 'damaged', 'concept_id': 'C1881662', 'confidence': 0.8042823076248169}, {'entity': 'nerves', 'concept_id': 'C0027740', 'confidence': 1.0}, {'entity': 'high-risk', 'concept_id': 'C0556482', 'confidence': 0.9005044102668762}, {'entity': 'inflammatory reactions', 'concept_id': 'C0021368', 'confidence': 0.9414709806442261}], [{'entity': 'Foreign bodies', 'concept_id': 'C0016542', 'confidence': 1.0}, {'entity': 'sarcoid', 'concept_id': 'C0036202', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_104",
"caption_rating": "7"
},
{
"": "1008118",
"caption": "The hamartoma involves both the epithelial component and a fibrous sheath around the hair follicle.",
"image_path": "LlPaENuqzVQ_image_05141636-bad5-4f26-a02c-efb30f02bb6a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['miniaturized hair follicle', 'mantle zone', 'stem cell area', 'bulge', 'apocrine gland', 'sebaceous gland', 'hamartoma', 'fibrous sheath', 'miniaturized hair follicle', 'mantle zone', 'stem cell area', 'bulge', 'apocrine gland', 'sebaceous gland', 'hamartoma', 'fibrous sheath', 'miniaturized hair follicle', 'mantle zone', 'stem cell area', 'bulge', 'apocrine gland', 'sebaceous gland', 'hamartoma', 'fibrous sheath']",
"noisy_text": " Like, it looks more like if there's, if I'm going to guess, like there's, I feel like there's a little bit of like, I would guess more like towards the, like a glandular. Yeah, well, it's, it's, it's a little miniaturized hair follicle. Nope. It's like this little guy here. It's like a little tiny follicle. And there's, we always think of three parts of the hair follicle. We think of the infundibulum, the isthmus, and we think of the inferior portion, but there's a very important part right around the isthmic part, just beneath the follicle, the infundibulum, and then where the inferior portion begins, that's known as the mantle zone. And that's kind of where all the action is. That's really kind of a stem cell area that sometimes those cells will form a little bulge there and they actually will end up forming an apocrine gland. Sometimes they'll end up forming a sebaceous gland. Sometimes they, you know, will just, they'll form, sometimes they form a little hammertoma, like you see right here. And they actually end up getting you this little sort of primitive little, it almost looks like a mini hair follicle that didn't really form. And then when you look at a hair follicle, it's comprised not only of the epithelial component, but there's also a periepithelial sheath around it, a fibrous sheath around the hair follicle. And so this is a hammertoma that involves both of those. So it's got a fibrous element to it. And then",
"corrected_text": " Like, it looks more like if there's, if I'm going to guess, like there's, I feel like there's a little bit of like, I would guess more like towards the, like a glandular. Yeah, well, it's, it's, it's a little miniaturized hair follicle. Nope. It's like this little guy here. It's like a little tiny follicle. And there's, we always think of three parts of the hair follicle. We think of the infundibulum, the isthmus, and we think of the inferior portion, but there's a very important part right around the isthmic part, just beneath the follicle, the infundibulum, and then where the inferior portion begins, that's known as the mantle zone. And that's kind of where all the action is. That's really kind of a stem cell area that sometimes those cells wiform a little bulge there and they actually wiend up forming an apocrine gland. Sometimes they'end up forming a sebaceous gland. Sometimes they, you know, will just, they'form, sometimes they form a little hamartoma, like you see right here. And they actually end up getting you this little sort of primitive little, it almost looks like a mini hair follicle that didn't really form. And then when you look at a hair follicle, it's comprised not only of the epithelial component, but there's also a periepithelial sheath around it, a fibrous sheath around the hair follicle. And so this is a hamartoma that involves both of those. So it's got a fibrous element to it. And then",
"med_umls_ids": "[[{'entity': 'narrator', 'concept_id': 'C1135957', 'confidence': 0.7711340188980103}, {'entity': 'miniaturized', 'concept_id': 'C0872350', 'confidence': 0.8111259341239929}, {'entity': 'hair follicle', 'concept_id': 'C0221971', 'confidence': 1.0}, {'entity': 'stem cell', 'concept_id': 'C0038250', 'confidence': 1.0}, {'entity': 'mantle zone', 'concept_id': 'C1512987', 'confidence': 1.0}], [{'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'mantle', 'concept_id': 'C0232445', 'confidence': 0.8497024178504944}, {'entity': 'zone', 'concept_id': 'C1710706', 'confidence': 1.0}, {'entity': 'bulge', 'concept_id': 'C0038999', 'confidence': 0.9999999403953552}, {'entity': 'apocrine gland', 'concept_id': 'C0003584', 'confidence': 0.9999998807907104}, {'entity': 'sebaceous gland', 'concept_id': 'C0036505', 'confidence': 1.0}, {'entity': 'hamartoma', 'concept_id': 'C0018552', 'confidence': 0.9999999403953552}], [{'entity': 'hamartoma', 'concept_id': 'C0018552', 'confidence': 0.9999999403953552}, {'entity': 'epithelial component', 'concept_id': 'C1707933', 'confidence': 0.8783122897148132}, {'entity': 'fibrous sheath', 'concept_id': 'C1185724', 'confidence': 1.0}, {'entity': 'hair follicle', 'concept_id': 'C0221971', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_105",
"caption_rating": "9"
},
{
"": "1006949",
"caption": "Spongiosis is the histologic reaction pattern observed.",
"image_path": "udoW6VSqsm4_image_10f1e59c-526f-45f9-9d88-cc22c8463445.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " Now what's this pattern, what are we looking at right here? What's the histologic reaction pattern? Oh, it's the spongiosis. Some spongiosis. So you can see some spongiosis in sep-derm, just like that case last night that you guys presented had spongiosis and psoriasiform hyperplasia. You can see some spongiosis in sep-derm, so it doesn't mean that they have allergic contact dermatitis or anything like that. So this is pretty good for sep-derm. If you want to say, well, there's a little more psoriasiform hyperplasia than usual there for seiboceriasis, try to avoid the term seiboceriasis because it's kind of a wastebasket a little bit. It doesn't commit to one diagnosis or the other. So I would favor sep-derm here more so than psoriasis, but it's a little more psoriasiform than usual. These are the clinical photos. You guys all know all about sep-derms.",
"corrected_text": " Now what's this pattern, what are we looking at right here? What's the histologic reaction pattern? Oh, it's the spongiosis. Some spongiosis. So you can see some spongiosis in sep-derm, just like that case last night that you guys presented had spongiosis and psoriasiform hyperplasia. You can see some spongiosis in sep-derm, so it doesn't mean that they have allergic contact dermatitis or anything like that. So this is pretty good for sep-derm. If you want to say, well, there's a little more psoriasiform hyperplasia than usual there for seborrheic dermatitis, try to avoid the term seborrheic dermatitis because it's kind of a wastebasket a little bit. It doesn't commit to one diagnosis or the other. So I would favor sep-derm here more so than psoriasis, but it's a little more psoriasiform than usual. These are the clinical photos. You guys all know all about sep-derms.",
"med_umls_ids": "[[{'entity': 'Spongiosis', 'concept_id': 'C0702120', 'confidence': 1.0}, {'entity': 'histologic reaction', 'concept_id': 'C0205462', 'confidence': 0.8118124008178711}], [{'entity': 'Spongiosis', 'concept_id': 'C0702120', 'confidence': 1.0}, {'entity': 'seborrheic dermatitis', 'concept_id': 'C0036508', 'confidence': 1.0}], [{'entity': 'Psoriasiform hyperplasia', 'concept_id': 'C3281279', 'confidence': 0.9999999403953552}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'seborrheic dermatitis', 'concept_id': 'C0036508', 'confidence': 1.0}, {'entity': 'psoriasis', 'concept_id': 'C0033860', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_106",
"caption_rating": "8"
},
{
"": "1008504",
"caption": "Molecular pathology should be coupled with clinical scenario, histologic features, and immunohistochemistry.",
"image_path": "QDb68_G1HR4_image_152660c1-7a02-4527-a98a-a5561a3fa697.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['synovial sarcoma', 'low-grade fibromyxoid sarcoma', 'FUS gene rearrangement']",
"noisy_text": " but I've seen very rare examples where there were very well differentiated areas in a synovial sarcoma that kind of had a fibrous look and looked similar to low-grade fibromyxoid sarcoma. So in that case, obviously you could use other stains like keratins and if you like TLE1 you could do that. And then in the end, if you have trouble, molecular pathology can help us out. Like I said earlier, these tumors, low-grade fibromyxoid sarcoma is defined by a translocation. The most common translocation is the translocation 716 which is between the genes FUS and CREB3L2. And there's also a small subset of these that have an alternate translocation which is between the FUS gene and the CREB3L1 gene. So FUS-CREB3L2 or FUS-CREB3L1 gene fusion can support the diagnosis. So you could use break apart fish for FUS. If the tumor looks like this and FUS is positive for FUS rearrangement, then you should be pretty good in calling it a low-grade fibromyxoid sarcoma. But do be aware that there are many other tumors in soft tissue pathology that have FUS rearrangements, myxoid liposarcoma and others. They usually have a different histologic appearance. So that's why you can never use, at least in my opinion, you shouldn't use molecular pathology by itself. You have to couple it with the clinical scenario and the histologic features and the immunostain findings. Put",
"corrected_text": " but I've seen very rare examples where there were very well differentiated areas in a synovial sarcoma that kind of had a fibrous look and looked similar to low-grade fibromyxoid sarcoma. So in that case, obviously you could use other stains like keratins and if you like TLE1 you could do that. And then in the end, if you have trouble, molecular pathology can help us out. Like I said earlier, these tumors, low-grade fibromyxoid sarcoma is defined by a translocation. The most common translocation is the translocation 716 which is between the genes FUS and CREB3L2. And there's also a small subset of these that have an alternate translocation which is between the FUS gene and the CREB3L1 gene. So FUS-CREB3L2 or FUS-CREB3L1 gene fusion can support the diagnosis. So you could use break apart fish for FUS. If the tumor looks like this and FUS is positive for FUS gene rearrangement, then you should be pretty good in calling it a low-grade fibromyxoid sarcoma. But do be aware that there are many other tumors in soft tissue pathology that have FUS gene rearrangements, myxoid liposarcoma and others. They usually have a different histologic appearance. So that's why you can never use, at least in my opinion, you shouldn't use molecular pathology by itself. You have to couple it with the clinical scenario and the histologic features and the immunohistochemistry findings. Put",
"med_umls_ids": "[[{'entity': 'Synovial sarcoma', 'concept_id': 'C0039101', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}], [{'entity': 'Keratin', 'concept_id': 'C0010803', 'confidence': 1.0}, {'entity': 'TLE1', 'concept_id': 'C1420752', 'confidence': 1.0}, {'entity': 'stains', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'differentiate', 'concept_id': 'C0205615', 'confidence': 0.9999998807907104}, {'entity': 'synovial sarcoma', 'concept_id': 'C0039101', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}], [{'entity': 'Low-grade fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.9999998807907104}, {'entity': 'translocation', 'concept_id': 'C0040715', 'confidence': 1.0}, {'entity': 'translocation', 'concept_id': 'C0040715', 'confidence': 1.0}, {'entity': 'FUS', 'concept_id': 'C0268696', 'confidence': 1.0}, {'entity': 'CREB3L2', 'concept_id': 'C1428221', 'confidence': 0.9999998807907104}, {'entity': 'genes', 'concept_id': 'C0017337', 'confidence': 1.0}], [{'entity': 'Break apart FISH', 'concept_id': 'C3831569', 'confidence': 0.7467014789581299}, {'entity': 'FUS', 'concept_id': 'C0268696', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}], [{'entity': 'Molecular pathology', 'concept_id': 'C0596962', 'confidence': 1.0}, {'entity': 'coupled', 'concept_id': 'C1948027', 'confidence': 1.0}, {'entity': 'clinical scenario', 'concept_id': 'C0205210', 'confidence': 0.6381967067718506}, {'entity': 'histologic features', 'concept_id': 'C1301121', 'confidence': 0.816085159778595}, {'entity': 'immunohistochemistry', 'concept_id': 'C0021044', 'confidence': 0.9999998807907104}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_107",
"caption_rating": "8"
},
{
"": "1005768",
"caption": "Distinguishing low-grade fibromyxoid sarcoma from myxofibrosarcoma can be done histologically with H and E staining.",
"image_path": "QDb68_G1HR4_image_26eba169-a38a-4e4c-beb5-90c792b38be4.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " So by that time the patient may have moved, forgotten all about the supposedly benign mass they had removed years and years ago and so that's why it took a long time for people to figure out that this was actually a malignancy. So the way that I'm making a separate video which I'll put a link up in the upper right hand corner here and also in the video description, I'm making a video to quickly explain a quick overview of explaining how to tell apart low grade fibromyxoid sarcoma from myxofibrosarcoma. The names sound similar but they're very different tumors histologically and are easy to separate most of the time just on H and E. But this video is going to be all about low grade fibromyxoid sarcoma so this is the more in-depth look",
"corrected_text": " So by that time the patient may have moved, forgotten all about the supposedly benign mass they had removed years and years ago and so that's why it took a long time for people to figure out that this was actually a malignancy. So the way that I'm making a separate video which I'll put a link up in the upper right hand corner here and also in the video description, I'm making a video to quickly explain a quick overview of explaining how to tell apart low grade fibromyxoid sarcoma from myxofibrosarcoma. The names sound similar but they're very different tumors histologically and are easy to separate most of the time just on H and E. But this video is going to be all about low grade fibromyxoid sarcoma so this is the more in-depth look",
"med_umls_ids": "[[{'entity': 'benign mass', 'concept_id': 'C0741729', 'confidence': 0.824069619178772}, {'entity': 'malignancy', 'concept_id': 'C0006826', 'confidence': 1.0}], [{'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'myxofibrosarcoma', 'concept_id': 'C3714524', 'confidence': 1.0}, {'entity': 'histologically', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'H', 'concept_id': 'C0011892', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_108",
"caption_rating": "8"
},
{
"": "1006346",
"caption": "The lesion tends to occur along the ulnar aspect of the fifth digit and can be bilateral.",
"image_path": "8S4LeiO6Bbk_image_89afc7b2-8d75-4b3c-9eff-ab85550d9c16.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['nerve fascicles', 'spindle-shaped cells', 'rudimentary supernumerary digit', 'ulnar aspect of the fifth digit', 'acquired digital fibroma', 'acquired digital fibrokeratoma', 'trichilemmal cyst', 'nerve fascicles', 'spindle-shaped cells', 'rudimentary supernumerary digit', 'ulnar aspect of the fifth digit', 'acquired digital fibroma', 'acquired digital fibrokeratoma', 'trichilemmal cyst']",
"noisy_text": " core here we've got several well-defined nerve fascicles and the spindled cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions of course tend to occur along the ulnar eye aspect of the fifth digit. They're not infrequently bilateral and the key differential here of course is an acquired digital fibroma or an acquired digital fibrocarotoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if",
"corrected_text": " core here we've got several well-defined nerve fascicles and the spindle cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions of course tend to occur along the ulnar eye aspect of the fifth digit. They're not infrequently bilateral and the key differential here of course is an acquired digital fibroma or an acquired digital fibrokeratoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if",
"med_umls_ids": "[[{'entity': 'Well-defined nerve fascicles', 'concept_id': 'C1185741', 'confidence': 0.5682494640350342}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'S100', 'concept_id': 'C3273837', 'confidence': 1.0}, {'entity': 'SOX10', 'concept_id': 'C1420317', 'confidence': 0.9999998807907104}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'rudimentary supernumerary digit', 'concept_id': 'C0152427', 'confidence': 0.8142021894454956}], [{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'ulnar', 'concept_id': 'C0442044', 'confidence': 1.0}, {'entity': 'aspect', 'concept_id': 'C1547011', 'confidence': 1.0}, {'entity': 'fifth digit', 'concept_id': 'C0230403', 'confidence': 0.912693440914154}, {'entity': 'bilateral', 'concept_id': 'C0238767', 'confidence': 1.0}], [{'entity': 'differential diagnosis', 'concept_id': 'C0011906', 'confidence': 1.0}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}, {'entity': 'digital fibroma', 'concept_id': 'C4538745', 'confidence': 0.8997364640235901}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}], [{'entity': 'Trichilemmal cyst', 'concept_id': 'C2266788', 'confidence': 1.0}, {'entity': 'biopsy specimen', 'concept_id': 'C0677862', 'confidence': 1.0}, {'entity': 'slide number', 'concept_id': 'C3828004', 'confidence': 0.8261933326721191}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_109",
"caption_rating": "8"
},
{
"": "1006029",
"caption": "Extravasated erythrocytes are frequently seen at the periphery of the tumor.",
"image_path": "8S4LeiO6Bbk_image_aa903496-ae7f-4150-9b54-0225f8d20fbe.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['dilated vascular channels', 'papillary projections', 'enlarged endothelial cells', 'compressed vascular channels', 'extravasated erythrocytes']",
"noisy_text": " which will slowly risk halt. These lesions will stain, frequently with CD34, but also are strongly positive for D240. So they probably are of lymphatic origin rather than vascular origin. What one looks for is a biphasic vascular tumor with this central area characterized by these dilated vascular channels. Let's look at the bottom piece, which frequently do contain these papillary projections, which protrude into the lumina, these plump endothelial cells, and then at the periphery, more compressed vascular channels, which dissect between collagen bundles. And it's at the periphery one frequently sees extravasated erythrocytes, siderophages, and",
"corrected_text": " which will slowly risk halt. These lesions will stain, frequently with CD34, but also are strongly positive for D240. So they probably are of lymphatic origin rather than vascular origin. What one looks for is a biphasic vascular tumor with this central area characterized by these dilated vascular channels. Let's look at the bottom piece, which frequently do contain these papillary projections, which protrude into the lumina, these plump endothelial cells, and then at the periphery, more compressed vascular channels, which dissect between collagen bundles. And it's at the periphery one frequently sees extravasated erythrocytes, siderophages, and",
"med_umls_ids": "[[{'entity': 'Lesions', 'concept_id': 'C0221198', 'confidence': 1.0}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'CD34', 'concept_id': 'C0054953', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'D240', 'concept_id': 'C3766973', 'confidence': 0.5323090553283691}, {'entity': 'lymphatic origin', 'concept_id': 'C0229889', 'confidence': 0.7706887125968933}, {'entity': 'vascular origin', 'concept_id': 'C0395959', 'confidence': 0.7819716334342957}], [{'entity': 'biphasic', 'concept_id': 'C0205184', 'confidence': 1.0}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'dilated', 'concept_id': 'C0700124', 'confidence': 0.9999999403953552}, {'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}, {'entity': 'central area', 'concept_id': 'C0929543', 'confidence': 0.8492603302001953}], [{'entity': 'Papillary projections', 'concept_id': 'C0016538', 'confidence': 0.7451471090316772}, {'entity': 'bottom piece', 'concept_id': 'C1511276', 'confidence': 0.722324788570404}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}], [{'entity': 'Enlarged endothelial cells', 'concept_id': 'C0423263', 'confidence': 0.7785332202911377}, {'entity': 'papillary projections', 'concept_id': 'C0016538', 'confidence': 0.7451471090316772}], [{'entity': 'Compressed vascular channels', 'concept_id': 'C1336948', 'confidence': 0.5993747711181641}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}], [{'entity': 'Extravasated', 'concept_id': 'C0015376', 'confidence': 0.868863582611084}, {'entity': 'erythrocytes', 'concept_id': 'C0014772', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_110",
"caption_rating": "9"
},
{
"": "1008248",
"caption": "Possible diagnoses for eosinophilic inflammation in the esophagus, enteritis, or colitis.",
"image_path": "r7OA0Trj5hQ_image_738b0f80-c875-4e25-b895-5b195c1eee12.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['cryptitis', 'crypt abscess', 'variation in size', 'granulomas in the lamina propria', 'cryptitis']",
"noisy_text": " If it is esophagus, it is eosinophilic esophagitis, eosinophilic entritis, eosinophilic colitis. So eosinophilic gastroenteritis. Here it is a cryptitis and cryptopsis. And the glands are also pushed well apart. The glands are showing variation in size, shape, distribution. So this is chronic colitis with activity. These are granulomas in the lamina propria. Think of tuberculosis in India, sarcoidosis, fungal infections, or idiopathic, or foreign bodies. So those are all the four main things. Any granuloma, infectious or non-infectious. When infectious,",
"corrected_text": " If it is esophagus, it is eosinophilic esophagitis, eosinophilic enteritis, eosinophilic colitis. So eosinophilic gastroenteritis. Here it is a cryptitis and crypt abscess. And the glands are also pushed well apart. The glands are showing variation in size, shape, distribution. So this is chronic colitis with activity. These are granulomas in the lamina propria. Think of tuberculosis in India, sarcoidosis, fungal infections, or idiopathic, or foreign bodies. So those are all the four main things. Any granuloma, infectious or non-infectious. When infectious,",
"med_umls_ids": "[[{'entity': 'diagnoses', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'eosinophilic', 'concept_id': 'C0333930', 'confidence': 1.0}, {'entity': 'inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}, {'entity': 'esophagus', 'concept_id': 'C0014876', 'confidence': 1.0}, {'entity': 'enteritis', 'concept_id': 'C0014335', 'confidence': 1.0}, {'entity': 'colitis', 'concept_id': 'C0009319', 'confidence': 1.0}], [{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'chronic colitis', 'concept_id': 'C0267375', 'confidence': 0.9999999403953552}, {'entity': 'activity', 'concept_id': 'C0026606', 'confidence': 1.0}, {'entity': 'granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_111",
"caption_rating": "7"
},
{
"": "1004852",
"caption": "The lesion is a small benign papule with dilated blood vessels and proliferating sebaceous lobules. It has two components: a fibrous component and an epithelial component, which includes an epithelial sebaceous gland.",
"image_path": "LlPaENuqzVQ_image_19aa8aed-777d-42ce-86ba-d1ced38cb3a0.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['dilated blood vessels', 'sebaceous lobules', 'fibrous component', 'epithelial component', 'epithelial sebaceous gland', 'teensy small follicle', 'dilated blood vessels', 'sebaceous lobules', 'fibrous component', 'epithelial component', 'epithelial sebaceous gland', 'teensy small follicle']",
"noisy_text": " And then there's some dilated blood vessels and whatnot, background sebaceous lobules that are proliferating. This may be kind of an incipient one of them, but this is what we're looking at here. So it's a small teensy tiny papule. And it's, if it's a neoplasm, it's got a two components to it. It's got a fibrous component, like right here. And then it's also got this epithelial component. What do you think this, what kind of differentiation are we looking at right here? Right, I feel it, right. So this is epithelial sebaceous gland. That's epithelium, little teensy small follicle right there. What's this? Is it closer to this or this? Sorry. Like, it",
"corrected_text": " And then there's some dilated blood vessels and whatnot, background sebaceous lobules that are proliferating. This may be kind of an incipient one of them, but this is what we're looking at here. So it's a small teensy tiny papule. And it's, if it's a neoplasm, it's got a two components to it. It's got a fibrous component, like right here. And then it's also got this epithelial component. What do you think this, what kind of differentiation are we looking at right here? Right, I feel it, right. So this is epithelial sebaceous gland. That's epithelium, little teensy small follicle right there. What's this? Is it closer to this or this? Sorry. Like, it",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'benign papule', 'concept_id': 'C0205183', 'confidence': 0.7019047737121582}, {'entity': 'dilated blood vessels', 'concept_id': 'C0424830', 'confidence': 1.0}, {'entity': 'proliferating sebaceous lobules', 'concept_id': 'C0221946', 'confidence': 0.7654090523719788}, {'entity': 'components', 'concept_id': 'C0449432', 'confidence': 1.0}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}, {'entity': 'epithelial component', 'concept_id': 'C1707933', 'confidence': 0.8783122897148132}, {'entity': 'epithelial sebaceous gland', 'concept_id': 'C0036505', 'confidence': 0.7906183004379272}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_112",
"caption_rating": "9"
},
{
"": "1004879",
"caption": "In some cases, there may be no well-differentiated or conventional cancer present, only small cell carcinoma.",
"image_path": "iklRyY1nBIE_image_f478f409-67bd-40fc-b80f-d5ca0105e9d1.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['High-grade prostatic adenocarcinoma intimately associated with small cell carcinoma.']",
"noisy_text": " sometimes you get bladder neck tissue in the same sample. And when we have a discussion tomorrow about the bladder cases, the same thing happens in the bladder. You can get a so-called TUR-BT sample that has prostate tissue present. In the prostate, you can have a TUR-P sample that has bladder neck tissue present. And in this particular case, as I said, we were fortunate enough to have high-grade conventional prostate cancer intimately associated with this small cell carcinoma. So it's most likely the differentiation of that. But there are some cases in which there is no well-differentiated or conventional cancer anywhere. All you see is small cell. And then the clinicians may ask, where is this coming from? Is this coming from the prostate? Is this coming from the bladder? And sometimes it's a challenge. Some of us would say it's probably an academic question because they're going to be treated the same way. But sometimes our clinical colleagues want to know. Because things like androgen deprivation therapy are off the table if it's coming from the prostate. And there are different ways one can figure that out. If you're fortunate enough to have egg expression, because studies have shown this, if you're fortunate enough",
"corrected_text": " sometimes you get bladder neck tissue in the same sample. And when we have a discussion tomorrow about the bladder cases, the same thing happens in the bladder. You can get a so-called TUR-BT sample that has prostate tissue present. In the prostate, you can have a TUR-P sample that has bladder neck tissue present. And in this particular case, as I said, we were fortunate enough to have high-grade conventional prostate cancer intimately associated with this small cell carcinoma. So it's most likely the differentiation of that. But there are some cases in which there is no well-differentiated or conventional cancer anywhere. All you see is small cell. And then the clinicians may ask, where is this coming from? Is this coming from the prostate? Is this coming from the bladder? And sometimes it's a challenge. Some of us would say it's probably an academic question because they're going to be treated the same way. But sometimes our clinical colleagues want to know. Because things like androgen deprivation therapy are off the table if it's coming from the prostate. And there are different ways one can figure that out. If you're fortunate enough to have egg expression, because studies have shown this, if you're fortunate enough",
"med_umls_ids": "[[{'entity': 'Bladder', 'concept_id': 'C0005682', 'confidence': 1.0}, {'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'prostate tissue', 'concept_id': 'C1514521', 'confidence': 0.8824390769004822}, {'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}], [{'entity': 'High-grade prostatic adenocarcinoma', 'concept_id': 'C3642254', 'confidence': 0.7883367538452148}, {'entity': 'associated with', 'concept_id': 'C0332281', 'confidence': 1.0}, {'entity': 'small cell carcinoma', 'concept_id': 'C0149925', 'confidence': 1.0}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}], [{'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'conventional', 'concept_id': 'C0439858', 'confidence': 1.0}, {'entity': 'cancer', 'concept_id': 'C0006826', 'confidence': 0.9999998807907104}, {'entity': 'present', 'concept_id': 'C0150312', 'confidence': 0.9999998807907104}, {'entity': 'small cell carcinoma', 'concept_id': 'C0149925', 'confidence': 1.0}], [{'entity': 'Differentiating', 'concept_id': 'C0205615', 'confidence': 1.0}, {'entity': 'origin', 'concept_id': 'C0079946', 'confidence': 1.0}, {'entity': 'small cell carcinoma', 'concept_id': 'C0149925', 'confidence': 1.0}, {'entity': 'treatment', 'concept_id': 'C0039798', 'confidence': 1.0}, {'entity': 'decisions', 'concept_id': 'C0679006', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_113",
"caption_rating": "7"
},
{
"": "1009189",
"caption": "Identification of different types of protein fibers in connective tissue.",
"image_path": "ib991vTA67A_image_8719a918-3d61-4562-a7aa-46ed30bc631f.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Head and Neck']",
"roi_text": "['fat, fatter, thick, pink protein fibers']",
"noisy_text": " and three places where you could find this type of Connective Tissue. So here's this Connective Tissue again, just write it down, and the next question is what type of protein fibers are these skinny ones, these skinny hair-like protein fibers? Find those protein fibers first, the skinny hair-like protein fibers, what are those called? And next, what are these fat, fatter, thick, pink protein fibers called? What are these protein fibers called? Here's a close-up of a Connective Tissue you've seen, so this is going to be number twenty-four, what type",
"corrected_text": " and three places where you could find this type of Connective Tissue. So here's this Connective Tissue again, just write it down, and the next question is what type of protein fibers are these skinny ones, these skinny hair-like protein fibers? Find those protein fibers first, the skinny hair-like protein fibers, what are those called? And next, what are these fat, fatter, thick, pink protein fibers called? What are these protein fibers called? Here's a close-up of a Connective Tissue you've seen, so this is going to be number twenty-four, what type",
"med_umls_ids": "[[{'entity': 'Identification', 'concept_id': 'C0020792', 'confidence': 1.0}, {'entity': 'protein fibers', 'concept_id': 'C0000696', 'confidence': 0.7645217180252075}, {'entity': 'connective tissue', 'concept_id': 'C0009780', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1152.0",
"id": "test_114",
"caption_rating": "7"
},
{
"": "1008810",
"caption": "Low-grade fibromyxoid sarcoma is defined by a translocation, with the most common being the translocation 716 between the FUS and CREB3L2 genes.",
"image_path": "QDb68_G1HR4_image_bf40e274-39ca-4e88-8697-cd860ef12b46.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['synovial sarcoma', 'low-grade fibromyxoid sarcoma', 'FUS gene rearrangement']",
"noisy_text": " but I've seen very rare examples where there were very well differentiated areas in a synovial sarcoma that kind of had a fibrous look and looked similar to low-grade fibromyxoid sarcoma. So in that case, obviously you could use other stains like keratins and if you like TLE1 you could do that. And then in the end, if you have trouble, molecular pathology can help us out. Like I said earlier, these tumors, low-grade fibromyxoid sarcoma is defined by a translocation. The most common translocation is the translocation 716 which is between the genes FUS and CREB3L2. And there's also a small subset of these that have an alternate translocation which is between the FUS gene and the CREB3L1 gene. So FUS-CREB3L2 or FUS-CREB3L1 gene fusion can support the diagnosis. So you could use break apart fish for FUS. If the tumor looks like this and FUS is positive for FUS rearrangement, then you should be pretty good in calling it a low-grade fibromyxoid sarcoma. But do be aware that there are many other tumors in soft tissue pathology that have FUS rearrangements, myxoid liposarcoma and others. They usually have a different histologic appearance. So that's why you can never use, at least in my opinion, you shouldn't use molecular pathology by itself. You have to couple it with the clinical scenario and the histologic features and the immunostain findings. Put",
"corrected_text": " but I've seen very rare examples where there were very well differentiated areas in a synovial sarcoma that kind of had a fibrous look and looked similar to low-grade fibromyxoid sarcoma. So in that case, obviously you could use other stains like keratins and if you like TLE1 you could do that. And then in the end, if you have trouble, molecular pathology can help us out. Like I said earlier, these tumors, low-grade fibromyxoid sarcoma is defined by a translocation. The most common translocation is the translocation 716 which is between the genes FUS and CREB3L2. And there's also a small subset of these that have an alternate translocation which is between the FUS gene and the CREB3L1 gene. So FUS-CREB3L2 or FUS-CREB3L1 gene fusion can support the diagnosis. So you could use break apart fish for FUS. If the tumor looks like this and FUS is positive for FUS gene rearrangement, then you should be pretty good in calling it a low-grade fibromyxoid sarcoma. But do be aware that there are many other tumors in soft tissue pathology that have FUS gene rearrangements, myxoid liposarcoma and others. They usually have a different histologic appearance. So that's why you can never use, at least in my opinion, you shouldn't use molecular pathology by itself. You have to couple it with the clinical scenario and the histologic features and the immunohistochemistry findings. Put",
"med_umls_ids": "[[{'entity': 'Synovial sarcoma', 'concept_id': 'C0039101', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}], [{'entity': 'Keratin', 'concept_id': 'C0010803', 'confidence': 1.0}, {'entity': 'TLE1', 'concept_id': 'C1420752', 'confidence': 1.0}, {'entity': 'stains', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'differentiate', 'concept_id': 'C0205615', 'confidence': 0.9999998807907104}, {'entity': 'synovial sarcoma', 'concept_id': 'C0039101', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}], [{'entity': 'Low-grade fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.9999998807907104}, {'entity': 'translocation', 'concept_id': 'C0040715', 'confidence': 1.0}, {'entity': 'translocation', 'concept_id': 'C0040715', 'confidence': 1.0}, {'entity': 'FUS', 'concept_id': 'C0268696', 'confidence': 1.0}, {'entity': 'CREB3L2', 'concept_id': 'C1428221', 'confidence': 0.9999998807907104}, {'entity': 'genes', 'concept_id': 'C0017337', 'confidence': 1.0}], [{'entity': 'Break apart FISH', 'concept_id': 'C3831569', 'confidence': 0.7467014789581299}, {'entity': 'FUS', 'concept_id': 'C0268696', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}], [{'entity': 'Molecular pathology', 'concept_id': 'C0596962', 'confidence': 1.0}, {'entity': 'coupled', 'concept_id': 'C1948027', 'confidence': 1.0}, {'entity': 'clinical scenario', 'concept_id': 'C0205210', 'confidence': 0.6381967067718506}, {'entity': 'histologic features', 'concept_id': 'C1301121', 'confidence': 0.816085159778595}, {'entity': 'immunohistochemistry', 'concept_id': 'C0021044', 'confidence': 0.9999998807907104}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_115",
"caption_rating": "8"
},
{
"": "1004817",
"caption": "Presence of at least two cell types with round to oval nuclei and faint eosinophilic to pale gray cytoplasm.",
"image_path": "8S4LeiO6Bbk_image_a0d9ca4b-d2c9-43b5-be52-eea868bbd3fd.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['epithelial tumor', 'cytoplasm', 'vesicular chromatin pattern', 'lymphocytes', 'duct formation', 'epithelial tumor', 'cytoplasm', 'vesicular chromatin pattern', 'lymphocytes', 'duct formation']",
"noisy_text": " If we move to higher power, we can see that we're dealing with an epithelial rather than a mosaicable tumor. We've got interconnected cords and strands. We have somewhat of a ribiform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of the cells are round to oval. They're fairly large. These cells have some faint eosinophilic to pale gray cytoplasm, although this cytoplasm is kind of difficult to see. Some of these cells have an evenly dispersed or vesicular chromatin pattern, and other nuclei are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and",
"corrected_text": " If we move to higher power, we can see that we're dealing with an epithelial rather than a mesenchymal tumor. We've got interconnected cords and strands. We have somewhat of a cribriform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of the cells are round to oval. They're fairly large. These cells have some faint eosinophilic to pale gray cytoplasm, although this cytoplasm is kind of difficult to see. Some of these cells have an evenly dispersed or vesicular chromatin pattern, and other nuclei are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'epithelial tumor', 'concept_id': 'C1368683', 'confidence': 0.9999999403953552}, {'entity': 'cords', 'concept_id': 'C0034869', 'confidence': 0.801885187625885}, {'entity': 'strands', 'concept_id': 'C0600383', 'confidence': 0.800572395324707}], [{'entity': 'Cribriform pattern', 'concept_id': 'C1333163', 'confidence': 1.0}, {'entity': 'loose', 'concept_id': 'C0205407', 'confidence': 1.0}, {'entity': 'edematous', 'concept_id': 'C0013604', 'confidence': 1.0}, {'entity': 'vascular stroma', 'concept_id': 'C0005847', 'confidence': 0.8046398758888245}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'cell types', 'concept_id': 'C0007634', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'eosinophilic', 'concept_id': 'C0333930', 'confidence': 1.0}, {'entity': 'pale', 'concept_id': 'C0030232', 'confidence': 1.0}, {'entity': 'gray cytoplasm', 'concept_id': 'C0010834', 'confidence': 0.8177905678749084}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'duct', 'concept_id': 'C0687028', 'confidence': 1.0}, {'entity': 'formation', 'concept_id': 'C0220781', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_116",
"caption_rating": "8"
},
{
"": "1008398",
"caption": "Chemotherapy associated colitis can mimic inflammatory bowel disease.",
"image_path": "sDFjOtMAYrk_image_f1a2a4a2-c044-49f8-8c53-33f5703c356d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "[]",
"noisy_text": " they're receiving radiation, is a lot of eosinophils and even intracryptal eosinophilic microapses. You don't see a lot in the way of neutrophils. You may see some neutrophils in the cytoplasm of the nuclei, like intracellular intracytoplasmic neutrophils, but not really neutrophilic microapses. And the other thing you might see is intracytoplasmic vacuoles degenerating vacuoles. So, this is a good example of chemotherapy associated colitis, a mimic of inflammatory bowel disease. Oh, this is a good one. With that degree, the mild degree of architectural distortion is what's making me fall short of saying this is for sure IBD. So, I would be descriptive and I would say, you know,",
"corrected_text": " they're receiving radiation, is a lot of eosinophils and even intracryptal eosinophilic microapses. You don't see a lot in the way of neutrophils. You may see some neutrophils in the cytoplasm of the nuclei, like intracellular intracytoplasmic neutrophils, but not really neutrophilic microapses. And the other thing you might see is intracytoplasmic vacuoles degenerating vacuoles. So, this is a good example of chemotherapy associated colitis, a mimic of inflammatory bowel disease. Oh, this is a good one. With that degree, the mild degree of architectural distortion is what's making me fall short of saying this is for sure IBD. So, I would be descriptive and I would say, you know,",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'intracryptal', 'concept_id': 'C3315370', 'confidence': 0.626490592956543}, {'entity': 'microapses', 'concept_id': 'C0700712', 'confidence': 0.5626617074012756}, {'entity': 'patients', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'radiation', 'concept_id': 'C0034519', 'confidence': 1.0}], [{'entity': 'intracellular', 'concept_id': 'C0175996', 'confidence': 1.0}, {'entity': 'intracytoplasmic', 'concept_id': 'C0230649', 'confidence': 0.8670988082885742}, {'entity': 'neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'degenerating', 'concept_id': 'C0011164', 'confidence': 1.0}, {'entity': 'vacuoles', 'concept_id': 'C0042219', 'confidence': 1.0}], [{'entity': 'Chemotherapy', 'concept_id': 'C0013216', 'confidence': 1.0}, {'entity': 'colitis', 'concept_id': 'C0009319', 'confidence': 1.0}, {'entity': 'inflammatory bowel disease', 'concept_id': 'C0021390', 'confidence': 1.0}], [{'entity': 'Mild', 'concept_id': 'C1513302', 'confidence': 1.0}, {'entity': 'degree', 'concept_id': 'C0441889', 'confidence': 1.0}, {'entity': 'architectural distortion', 'concept_id': 'C2826609', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_117",
"caption_rating": "7"
},
{
"": "1008866",
"caption": "Diagnosis of pigmented Bowen\u2019s disease or pigmented squamous cell carcinoma.",
"image_path": "8S4LeiO6Bbk_image_e5790862-3f0c-49bc-bd05-fc6c6a29c969.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['abnormal maturation of keratinocytes', 'hyperchromatic cells', 'melanin pigment', 'dendritic melanocytes', 'abnormal maturation of keratinocytes', 'hyperchromatic cells', 'melanin pigment', 'dendritic melanocytes']",
"noisy_text": " I think would be reasonable considerations. However, if we move to higher power and begin to study the epidermis a little bit more carefully we can see that there's clear-cut abnormal maturation here. We've got full thickness keratinocytic atypia with nucleic acid or pleomorphic and hyperchromatic. There is abnormal maturation with even abnormal hyperchromatic perikaratotic cells within the stratum corneum. There's an increased amount of melanin pigment pressed within the basal layer and we can see that we've got an increased amount of melanin pigment and even a few dendritic melanocytes within the epidermis and so what we've got here is an example of pigmented Bowen's disease or pigmented squamous cell carcinoma. One could see similar changes in lesions",
"corrected_text": " I think would be reasonable considerations. However, if we move to higher power and begin to study the epidermis a little bit more carefully we can see that there's clear-cut abnormal maturation of keratinocytes here. We've got full thickness keratinocytic atypia with nucleic acid or pleomorphic and hyperchromatic. There is abnormal maturation with even abnormal hyperchromatic parakeratotic cells within the stratum corneum. There's an increased amount of melanin pigment pressed within the basal layer and we can see that we've got an increased amount of melanin pigment and even a few dendritic melanocytes within the epidermis and so what we've got here is an example of pigmented Bowen 's disease's disease or pigmented squamous cell carcinoma. One could see similar changes in lesions",
"med_umls_ids": "[[{'entity': 'Abnormal', 'concept_id': 'C0205161', 'confidence': 1.0}, {'entity': 'maturation', 'concept_id': 'C0678723', 'confidence': 1.0}, {'entity': 'keratinocytes', 'concept_id': 'C0022567', 'confidence': 1.0}, {'entity': 'thickness', 'concept_id': 'C1280412', 'confidence': 1.0}, {'entity': 'keratinocytic atypia', 'concept_id': 'C0741302', 'confidence': 0.6335055828094482}, {'entity': 'hyperchromatic cells', 'concept_id': 'C0333911', 'confidence': 0.823300302028656}, {'entity': 'stratum corneum', 'concept_id': 'C0221921', 'confidence': 1.0}], [{'entity': 'Increased', 'concept_id': 'C0205217', 'confidence': 1.0}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}, {'entity': 'pigment', 'concept_id': 'C0031911', 'confidence': 1.0}, {'entity': 'dendritic melanocytes', 'concept_id': 'C0025201', 'confidence': 0.7694142460823059}, {'entity': 'epidermis', 'concept_id': 'C0014520', 'confidence': 1.0}], [{'entity': 'Diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'Bowen\u2019s disease', 'concept_id': 'C0006079', 'confidence': 0.9730859994888306}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'squamous cell carcinoma', 'concept_id': 'C0007137', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_118",
"caption_rating": "8"
},
{
"": "1006185",
"caption": "Presence of basal cells at the periphery indicates that the tumor is not invasive.",
"image_path": "iklRyY1nBIE_image_f98d30b9-5304-4210-b9f8-92fc429a8533.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['basal cells at the periphery', 'enlarged nuclei', 'intraductal carcinoma of the prostate', 'adjacent invasive tumor', 'previously benign gland', 'basal cells at the periphery', 'enlarged nuclei', 'intraductal carcinoma of the prostate', 'adjacent invasive tumor', 'previously benign gland']",
"noisy_text": " Let me show you what the cocktail looks like. Again, this is the pin three, or some call it pin four. You have the P63, you have the hemoglobin cytokeratin, and then you have the racemase, which is the pink chromogen. And as you can see, as I demonstrated on the H&E, basal cells are indeed present. This is too much for high-grade pin. This is basically what is called a solid cribriform kind of pattern, in which over 50% of the lumen is filled by tumor cells. So this is way too much for high-grade pin. But it's not invasive, because you have basal cells at the periphery. And the nuclei are enlarged. These nuclei are about six times the size of normal prostate nuclei. So this case meets the criteria for introductal carcinoma of the prostate. There is an invasive component, which you can see is negative for basal cell markers. But you have the introductal component. And this is a very interesting entity. The vast majority of cases, and I'll show you the corresponding radical prostatectomy specimens in a second, but the vast majority of these so-called introductal carcinoma of the prostate is due to invasion, colonization by adjacent invasive tumor. And it usually occurs in patients that have high-volume tumors. When I show you the corresponding radical prostatectomies, you'll see what I'm talking about. You usually don't have this in patients in their radicals that have 5% prostate cancer or 10% prostate cancer. It's usually patients that have extensive prostate cancer involvement, and the invasive glands basically have nowhere else to go but to colonize adjacent benign glands. And I'll demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues,",
"corrected_text": " Let me show you what the cocktail looks like. Again, this is the pin three, or some call it pin four. You have the P63, you have the hemoglobin cytokeratin, and then you have the racemase, which is the AMACR. And as you can see, as I demonstrated on the H&E, basal cells are indeed present. This is too much for high-grade pin. This is basically what is called a solid cribriform kind of pattern, in which over 50% of the lumen is filled by tumor cells. So this is way too much for high-grade pin. But it's not invasive, because you have basal cells at the periphery. And the nuclei are enlarged. These nuclei are about six times the size of normal prostate nuclei. So this case meets the criteria for intraductal carcinoma of the prostate. There is an invasive component, which you can see is negative for basal cell markers. But you have the intraductal component. And this is a very interesting entity. The vast majority of cases, and I'll show you the corresponding radical prostatectomy specimens in a second, but the vast majority of these so-called intraductal carcinoma of the prostate is due to invasion, colonization by adjacent invasive tumor. And it usually occurs in patients that have high-volume tumors. When I show you the corresponding radical prostatectomies, you'll see what I'm talking about. You usually don't have this in patients in their radicals that have 5% prostate cancer or 10% prostate cancer. It's usually patients that have extensive prostate cancer involvement, and the invasive glands basically have nowhere else to go but to colonize adjacent benign glands. And I'demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues,",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'cocktail', 'concept_id': 'C0678420', 'confidence': 1.0}, {'entity': 'markers', 'concept_id': 'C0181734', 'confidence': 0.890313982963562}, {'entity': 'intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate diagnosis', 'concept_id': 'C0011900', 'confidence': 0.7927443981170654}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'basal cells', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}], [{'entity': 'Enlarged nuclei', 'concept_id': 'C4013177', 'confidence': 0.7774685621261597}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'normal', 'concept_id': 'C0205307', 'confidence': 1.0}], [{'entity': 'Intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'invasion', 'concept_id': 'C1269955', 'confidence': 1.0}, {'entity': 'colonization', 'concept_id': 'C4289767', 'confidence': 1.0}, {'entity': 'adjacent', 'concept_id': 'C0205117', 'confidence': 1.0}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}], [{'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'benign gland', 'concept_id': 'C0205183', 'confidence': 0.7986565828323364}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_119",
"caption_rating": "8"
},
{
"": "1005038",
"caption": "A florid host inflammatory response is present.",
"image_path": "iklRyY1nBIE_image_04cd57c4-7aac-4e75-8e6f-28cd9419e459.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['tumor', 'prostatic urethra', 'inflammatory response']",
"noisy_text": " is colonizing and destroying previously benign glands. And when you see that, it's usually, obviously, you want to exclude an introductory process, colonizing benign glands. But you also want to exclude secondary tumors. Secondary tumors do that, too. Colorectal carcinoma can do that. Urethelial carcinoma can do that. But this specular entity is arising not from the colon, even though it looks like it in areas. It's also not arising from the bladder. This is actually arising from the prostatic urethra. So this is what used to be the prostatic urethra, which has been destroyed by this tumor, because the tumor actually arose from here. I'll show you some early stages of this, early forms of this. This is like an advanced case. You can see there's a very florid host inflammatory response. As you'll",
"corrected_text": " is colonizing and destroying previously benign glands. And when you see that, it's usually, obviously, you want to exclude an introductory process, colonizing benign glands. But you also want to exclude secondary tumors. Secondary tumors do that, too. Colorectal carcinoma can do that. urothelial carcinoma can do that. But this specific entity is arising not from the colon, even though it looks like it in areas. It's also not arising from the bladder. This is actually arising from the prostatic urethra. So this is what used to be the prostatic urethra, which has been destroyed by this tumor, because the tumor actually arose from here. I'll show you some early stages of this, early forms of this. This is like an advanced case. You can see there's a very florid host inflammatory response. As you'll",
"med_umls_ids": "[[{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'colonizing', 'concept_id': 'C1300196', 'confidence': 0.61208176612854}, {'entity': 'destroying', 'concept_id': 'C1948029', 'confidence': 1.0}, {'entity': 'benign glands', 'concept_id': 'C1301287', 'confidence': 0.726940393447876}, {'entity': 'prostatic urethra', 'concept_id': 'C0458450', 'confidence': 1.0}], [{'entity': 'Secondary tumors', 'concept_id': 'C0027627', 'confidence': 0.9999999403953552}, {'entity': 'colorectal carcinoma', 'concept_id': 'C0009402', 'confidence': 0.9999998807907104}, {'entity': 'urothelial carcinoma', 'concept_id': 'C0007138', 'confidence': 1.0}, {'entity': 'destroy', 'concept_id': 'C0681205', 'confidence': 0.9999999403953552}, {'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}], [{'entity': 'host', 'concept_id': 'C1167395', 'confidence': 0.9999999403953552}, {'entity': 'inflammatory response', 'concept_id': 'C1155266', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_120",
"caption_rating": "7"
},
{
"": "1008336",
"caption": "C. diff can mimic ischemia, with pink and hyalinized lamina propria and architectural changes.",
"image_path": "sDFjOtMAYrk_image_c349f8b8-d567-4ceb-abc0-085ad1d06be2.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['lamina propria', 'pseudomembranes', 'ischemia', 'C. diff', 'lamina propria', 'pseudomembranes', 'ischemia', 'C. diff']",
"noisy_text": " will give you pseudomembranes. Ischemic injury can also give it to you. And the one thing to note is that, so this patient had C. difficile colitis by laboratory, but he was not responding to treatment and they just decided to take a biopsy. And you can see here that in the lamina propria is not hyalinized. Now, does that mean that ischemia is excluded? No, because if it's, you know, it depends on the clinical history. If it's recent ischemia that happened within, I don't know, 24, 48 hours, you know, the hyalinopropia may not have had time to hyalinize. How long does it take for the lamina propria to become pink? I don't know, but longer. So C. diff. Oh, another mimic of ischemia. And you can see why this mimics ischemia. The lamina propria is kind of pink and hyalinized. On top of that, there's actually some architectural distortion. This",
"corrected_text": " will give you pseudomembranes. Ischemic injury can also give it to you. And the one thing to note is that, so this patient had Clostridioides difficile colitis by laboratory, but he was not responding to treatment and they just decided to take a biopsy. And you can see here that in the lamina propria is not hyalinized. Now, does that mean that ischemia is excluded? No, because if it's, you know, it depends on the clinical history. If it's recent ischemia that happened within, I don't know, 24, 48 hours, you know, the hyalinopropia may not have had time to hyalinize. How long does it take for the lamina propria to become pink? I don't know, but longer. So C. diff. Oh, another mimic of ischemia. And you can see why this mimics ischemia. The lamina propria is kind of pink and hyalinized. On top of that, there's actually some architectural distortion. This",
"med_umls_ids": "[[{'entity': 'Pseudomembranes', 'concept_id': 'C0240821', 'confidence': 1.0}, {'entity': 'Clostridioides', 'concept_id': 'C4406271', 'confidence': 1.0}, {'entity': 'colitis', 'concept_id': 'C0009319', 'confidence': 1.0}, {'entity': 'ischemic injury', 'concept_id': 'C2945681', 'confidence': 0.8915668725967407}], [{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'hyalinized', 'concept_id': 'C0332230', 'confidence': 1.0}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}, {'entity': 'excluded', 'concept_id': 'C0332196', 'confidence': 1.0}], [{'entity': 'C. diff', 'concept_id': 'C0238106', 'confidence': 0.8398770093917847}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}, {'entity': 'pink', 'concept_id': 'C0332585', 'confidence': 1.0}, {'entity': 'hyalinized lamina propria', 'concept_id': 'C0332230', 'confidence': 0.7577076554298401}, {'entity': 'architectural changes', 'concept_id': 'C0003737', 'confidence': 0.7067119479179382}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_121",
"caption_rating": "7"
},
{
"": "1005976",
"caption": "The image shows goblet cells in gastric mucosa, which take blue color in Alcian blue and PAS color in gastric epithelium.",
"image_path": "r7OA0Trj5hQ_image_0baeb78a-9b1a-43f2-9fbf-1489590fba99.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Goblet cells in gastric mucosa', 'Peritoneal cells in the body of the stomach']",
"noisy_text": " So the best stain for H. pylori is careful examination of H&E. Here H&E picture showing goblet cells in a gastric mucosa. The goblet cells are taking blue color, in algean blue, whereas the gastric epithelium is taking the PAS color. So this is algean blue PAS, intersternal metaplasia of the gastric mucosa. Here the history is this biopsy is taken from the body of the stomach. In the body of the stomach, you have to see a lot of fried eggs. These are all the peritoneal cells in addition to mucincycletine cells and chief cells. These are the peritoneal cells. When you",
"corrected_text": " So the best stain for H. pylori is careful examination of H&E. Here H&E picture showing goblet cells in a gastric mucosa. The goblet cells are taking blue color, in Alcian blue, whereas the gastric epithelium is taking the PAS color. So this is Alcian blue PAS, intestinal metaplasia of the gastric mucosa. Here the history is this biopsy is taken from the body of the stomach. In the body of the stomach, you have to see a lot of fried eggs. These are all the peritoneal cells in addition to mucincycletine cells and chief cells. These are the peritoneal cells. When you",
"med_umls_ids": "[[{'entity': 'H. pylori', 'concept_id': 'C0079488', 'confidence': 1.0}, {'entity': 'visualized', 'concept_id': 'C0234621', 'confidence': 1.0}, {'entity': 'examination', 'concept_id': 'C0031809', 'confidence': 1.0}, {'entity': 'H&E stain', 'concept_id': 'C0523207', 'confidence': 1.0}], [{'entity': 'image', 'concept_id': 'C1696103', 'confidence': 1.0}, {'entity': 'goblet cells', 'concept_id': 'C0506994', 'confidence': 0.9999999403953552}, {'entity': 'gastric mucosa', 'concept_id': 'C0017136', 'confidence': 1.0}, {'entity': 'blue color', 'concept_id': 'C1260957', 'confidence': 1.0}, {'entity': 'Alcian blue', 'concept_id': 'C0001933', 'confidence': 1.0}, {'entity': 'PAS', 'concept_id': 'C0030125', 'confidence': 1.0}, {'entity': 'color', 'concept_id': 'C0009393', 'confidence': 1.0}, {'entity': 'gastric epithelium', 'concept_id': 'C0227208', 'confidence': 1.0}], [{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'body', 'concept_id': 'C0227230', 'confidence': 1.0}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'peritoneal cells', 'concept_id': 'C0031153', 'confidence': 0.7749612331390381}, {'entity': 'mucincycletine cells', 'concept_id': 'C0007586', 'confidence': 0.6177586317062378}, {'entity': 'chief cells', 'concept_id': 'C1516470', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_122",
"caption_rating": "8"
},
{
"": "1008548",
"caption": "The nuclei of the stratified cells reach the middle third and maintain polarity, with no prominent nuclei or cribriform/micropapillary formation.",
"image_path": "r7OA0Trj5hQ_image_e11f3585-603a-4ed6-9ae4-66b1567e4da2.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Stratified nuclei reaching middle third', 'Nuclei traveling in one direction', 'Maintained polarity', 'No prominent nuclei', 'No cribriform/micropapillary formation', 'Stratified nuclei reaching middle third', 'Nuclei traveling in one direction', 'Maintained polarity', 'No prominent nuclei', 'No cribriform/micropapillary formation']",
"noisy_text": " And this stratified nuclei reach the middle third. They are not touching the upper top of the apical membrane. They are reaching the middle third predominantly. Okay, that is one important point. And other one is, look at this nuclei. They are all traveling in one direction. So the polarity is maintained. Okay, so those two points are very important. And the third one is no prominent nuclei. Nuclei are not prominent. And the fourth point is, no cribriformic or micropapillary formation. So the predominant features you see here is the maintained polarity, nuclei reaching",
"corrected_text": " And this stratified nuclei reach the middle third. They are not touching the upper top of the apical membrane. They are reaching the middle third predominantly. Okay, that is one important point. And other one is, look at this nuclei. They are all traveling in one direction. So the polarity is maintained. Okay, so those two points are very important. And the third one is no prominent nuclei. Nuclei are not prominent. And the fourth point is, no cribriform pattern or micropapillary formation. So the predominant features you see here is the maintained polarity, nuclei reaching",
"med_umls_ids": "[[{'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'stratified cells', 'concept_id': 'C0205363', 'confidence': 0.7615563869476318}, {'entity': 'middle', 'concept_id': 'C0227972', 'confidence': 1.0}, {'entity': 'polarity', 'concept_id': 'C0596963', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'cribriform/micropapillary formation', 'concept_id': 'C1621425', 'confidence': 0.5390191674232483}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_123",
"caption_rating": "9"
},
{
"": "1006571",
"caption": "The narrator mentions cellular intramuscular myxoma and the challenges in differentiating it from fibrous and more cellular areas.",
"image_path": "QDb68_G1HR4_image_9663f836-2793-4daf-9f55-9b76c5b0cf75.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['myxoid features', 'fine delicate collagen', 'cellular intramuscular myxoma', 'fibrous areas', 'cellular areas', 'MUC4 stain', 'myxoid features', 'fine delicate collagen', 'cellular intramuscular myxoma', 'fibrous areas', 'cellular areas', 'MUC4 stain']",
"noisy_text": " Here's again the myxoid background I really think this is very helpful. The very very fine delicate collagen that you see. Now areas like this I think can kind of resemble what you see in a so-called cellular intramuscular myxoma. Intramuscular myxomas are usually very blue and myxoid very hypocellular but sometimes they get more fibrous and more cellular areas. And on a needle biopsy I think that can be challenging. So I think usually with some experience you can tell them apart on H and E most of the time but when I have any doubt I just do a MUC4 stain. The MUC4 is negative and on a needle it looks like a myxoma with some kind of fibrous or a little bit more cellular areas and then I just say that it's probably a cellular intramuscular myxoma. So I think MUC4",
"corrected_text": " Here's again the myxoid background I really think this is very helpful. The very very fine delicate collagen that you see. Now areas like this I think can kind of resemble what you see in a so-called cellular intramuscular myxoma. Intramuscular myxomas are usually very blue and myxoid very hypocellular but sometimes they get more fibrous and more cellular areas. And on a needle biopsy I think that can be challenging. So I think usually with some experience you can tell them apart on H and E most of the time but when I have any doubt I just do a MUC4 stain. The MUC4 is negative and on a needle it looks like a myxoma with some kind of fibrous or a little bit more cellular areas and then I just say that it's probably a cellular intramuscular myxoma. So I think MUC4",
"med_umls_ids": "[[{'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'myxoid', 'concept_id': 'C0205295', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}], [{'entity': 'narrator', 'concept_id': 'C1135957', 'confidence': 0.7711340188980103}, {'entity': 'cellular', 'concept_id': 'C0007634', 'confidence': 0.9999999403953552}, {'entity': 'intramuscular', 'concept_id': 'C0442117', 'confidence': 1.0}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}, {'entity': 'cellular areas', 'concept_id': 'C0007634', 'confidence': 0.7882957458496094}], [{'entity': 'MUC4', 'concept_id': 'C1417496', 'confidence': 0.9999999403953552}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'confirm', 'concept_id': 'C0521093', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'cellular intramuscular myxoma', 'concept_id': 'C1334260', 'confidence': 0.8910117149353027}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_124",
"caption_rating": "7"
},
{
"": "1008012",
"caption": "Presence of pigmented histiocytes.",
"image_path": "8S4LeiO6Bbk_image_7825d703-9cc5-4cb1-85b8-c798c8e0ebd0.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['spindle-shaped cells']",
"noisy_text": " these collagen balls that are being surrounded by cells that have a somewhat spindled shape. The nuclei are spindled over our fusiform and they're kind of wrapping around these collagen bundles. In this same area, we can begin to see some lipophagia. So we see these large histiocytes containing lipid. Some of them are multi-nucleated and some of these are actually ringed siderophages. So we see large multi-nucleated histiocytes with a ring of nuclei and they contain not only lipid vacuoles but hemocentaurant. And these are particularly common in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes",
"corrected_text": " these collagen balls that are being surrounded by cells that have a somewhat spindle-shaped. The nuclei are spindle-shaped over our fusiform and they're kind of wrapping around these collagen bundles. In this same area, we can begin to see some lipophagic. So we see these large histiocytes containing lipid. Some of them are multi-nucleated and some of these are actually ringed siderophages. So we see large multinucleated histiocytes with a ring of nuclei and they contain not only lipid vacuoles but hemosiderin. And these are particularly common in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'collagen balls', 'concept_id': 'C0009325', 'confidence': 0.7217866778373718}, {'entity': 'surrounded', 'concept_id': 'C1282914', 'confidence': 1.0}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}], [{'entity': 'Lipophagic cells', 'concept_id': 'C0007584', 'confidence': 0.5962335467338562}, {'entity': 'lipid vacuoles', 'concept_id': 'C1179126', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'ringed', 'concept_id': 'C0325501', 'confidence': 0.77345871925354}, {'entity': 'siderophages', 'concept_id': 'C1136253', 'confidence': 0.7251443266868591}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_125",
"caption_rating": "8"
},
{
"": "1008165",
"caption": "Comparison between schwannoma and neuroblastoma-like schwannoma, which has a round cell appearance around the edge of the nodules and can be difficult to distinguish from a neuroblastoma.",
"image_path": "QDb68_G1HR4_image_2d99b722-45c0-4960-9a82-7af6aaa3343b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " Now one other tumor that might enter the differential here is the so-called neuroblastoma-like variant of schwannoma or neurilomoma neuroblastoma-like schwannoma. It has also big collagen rich rosettes like this but it has a much more prominent round cell appearance around the edge of the rim of the nodules are very like small round blue cell almost look a little bit like the small round blue cells of a neuroblastoma which is why it's named that way but I've definitely seen pathologists have trouble telling those two apart telling a hyalinizing spindle cell tumor with giant rosettes. This tumor",
"corrected_text": " Now one other tumor that might enter the differential here is the so-called neuroblastoma-like variant of schwannoma or neurilomoma neuroblastoma-like schwannoma. It has also big collagen rich rosettes like this but it has a much more prominent round cell appearance around the edge of the rim of the nodules are very like small round blue cell almost look a little bit like the small round blue cells of a neuroblastoma which is why it's named that way but I've definitely seen pathologists have trouble telling those two apart telling a hyalinizing spindle cell tumor with giant rosettes. This tumor",
"med_umls_ids": "[[{'entity': 'Comparison', 'concept_id': 'C1707455', 'confidence': 1.0}, {'entity': 'schwannoma', 'concept_id': 'C0027809', 'confidence': 0.9999998807907104}, {'entity': 'neuroblastoma-like schwannoma', 'concept_id': 'C0027809', 'confidence': 0.6513785719871521}, {'entity': 'round cell', 'concept_id': 'C0487470', 'confidence': 1.0}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'edge', 'concept_id': 'C0205154', 'confidence': 1.0}, {'entity': 'nodules', 'concept_id': 'C0028259', 'confidence': 1.0}, {'entity': 'neuroblastoma', 'concept_id': 'C0027819', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_126",
"caption_rating": "8"
},
{
"": "1007293",
"caption": "Loss of cellular polarity and nuclear stratification reaching the top of the epithelium are signs of dysplasia.",
"image_path": "r7OA0Trj5hQ_image_32417ed6-24b1-40eb-80cd-0e707d494e66.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Loss of cellular polarity and nuclear stratification reaching the top of the epithelium', 'Mitosis', 'Apoptosis', 'Dysplasia', 'Loss of cellular polarity and nuclear stratification reaching the top of the epithelium', 'Mitosis', 'Apoptosis', 'Dysplasia']",
"noisy_text": " Look at this nuclei running like in this direction. Look at this nuclei running in this direction. So clearly, loss of polarity. And the nuclear stratification is reaching the top of the epithelium, marked apoptosis. It's too thick to see the mitosis, but here you can see the mitosis. So this is stratification, loss of mucin, mitosis, apoptosis. So this is dysplasia. But this dysplasia is the epithelium is reaching the top. And there is loss of polarity. And I don't see probably crib reforming maybe coming here. I don't see in the center of the picture. So I will think",
"corrected_text": " Look at this nuclei running like in this direction. Look at this nuclei running in this direction. So clearly, loss of polarity. And the nuclear stratification is reaching the top of the epithelium, marked apoptosis. It's too thick to see the mitosis, but here you can see the mitosis. So this is stratification, loss of mucin, mitosis, apoptosis. So this is dysplasia. But this dysplasia is the epithelium is reaching the top. And there is loss of polarity. And I don't see probably cribriform maybe coming here. I don't see in the center of the picture. So I will think",
"med_umls_ids": "[[{'entity': 'Loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'cellular polarity', 'concept_id': 'C0085304', 'confidence': 1.0}, {'entity': 'nuclear', 'concept_id': 'C0521447', 'confidence': 1.0}, {'entity': 'stratification', 'concept_id': 'C1514983', 'confidence': 1.0}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'dysplasia', 'concept_id': 'C0334044', 'confidence': 1.0}], [{'entity': 'Mitosis', 'concept_id': 'C0026255', 'confidence': 0.9999998807907104}, {'entity': 'apoptosis', 'concept_id': 'C0162638', 'confidence': 1.0}, {'entity': 'dysplastic epithelium', 'concept_id': 'C1512100', 'confidence': 0.8234760165214539}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_127",
"caption_rating": "9"
},
{
"": "1005041",
"caption": "Muscularization of the lamina propria is a criterion for mucosal prolapse in colon, particularly in solitary rectal ulcer syndrome.",
"image_path": "r7OA0Trj5hQ_image_357fb809-5787-4b42-97c0-fdc9d593edfd.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['muscularization of the lamina propria', 'gastric mucosa', 'chemical gastritis', 'antral biopsy', 'inflammation']",
"noisy_text": " and in cases of mucosal prolapse in colon. Remember that solitary rectal ulcer syndrome, which is totally misnomer. It is neither solitary, can be seen in other parts other than rectum. There may not be any ulcer, there is no syndrome. So the whole solitary rectal ulcer syndrome is a misnomer. But muscularization of the lamina propria is one of the criteria for mucosal prolapse that is happening in solitary rectal ulcer syndrome. And this is a gastric mucosa. Here when you see muscularization of the lamina propria, you have to think of chemical gastritis. Will it form surface changes? Lamina propria edema and muscularis mucosa coming into the lamina propria. These are the three criterias. When you see it in the anterobiopsy, think of chemical gastritis that can be seen in biliary reflux or NSAID use. Lot of inflammation results. Remember I",
"corrected_text": " and in cases of mucosal prolapse in colon. Remember that solitary rectal ulcer syndrome, which is totally misnomer. It is neither solitary, can be seen in other parts other than rectum. There may not be any ulcer, there is no syndrome. So the whole solitary rectal ulcer syndrome is a misnomer. But muscularization of the lamina propria is one of the criteria for mucosal prolapse that is happening in solitary rectal ulcer syndrome. And this is a gastric mucosa. Here when you see muscularization of the lamina propria, you have to think of chemical gastritis. Will it form surface changes? Lamina propria edema and muscularis mucosa coming into the lamina propria. These are the three criteria. When you see it in the endoscopic biopsy, think of chemical gastritis that can be seen in biliary reflux or NSAID use. Lot of inflammation results. Remember I",
"med_umls_ids": "[[{'entity': 'Muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'criterion', 'concept_id': 'C0243161', 'confidence': 1.0}, {'entity': 'mucosal prolapse', 'concept_id': 'C0034888', 'confidence': 0.826268196105957}, {'entity': 'colon', 'concept_id': 'C0009368', 'confidence': 1.0}, {'entity': 'solitary rectal ulcer syndrome', 'concept_id': 'C4274343', 'confidence': 0.9999999403953552}], [{'entity': 'Muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'gastric mucosa', 'concept_id': 'C0017136', 'confidence': 1.0}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}, {'entity': 'biliary reflux', 'concept_id': 'C0232483', 'confidence': 0.7931289672851562}, {'entity': 'NSAID', 'concept_id': 'C0003211', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_128",
"caption_rating": "9"
},
{
"": "1005006",
"caption": "Metastatic ductal carcinoma, like breast cancer, can be differentiated from other neoplasms based on its diffuse nature and extension to the surface.",
"image_path": "LlPaENuqzVQ_image_a31970dc-8873-40ea-8c59-5565a7d97016.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['Metastatic ductal carcinoma', 'Sclerosing epithelial neoplasm', 'Fibrous stroma', 'Calcification', 'Duct-like structures']",
"noisy_text": " I've never found any of these things to be helpful. And the other differential that sometimes comes up is the difference between metastatic ductal carcinoma like a breast cancer in this, that usually that's not that difficult of a diagnosis especially if it's diffused like that and it extends to the surface. Here's another sclerosing epithelial neoplasm. And notice the stroma here. Can you tell the difference between this stroma and the one we just looked at in the MAC? See how fibrous this stroma is. These are more basophilic cells. There's calcification here. There may be some little small duct-like structures at the top of the calcification. This is",
"corrected_text": " I've never found any of these things to be helpful. And the other differential that sometimes comes up is the difference between metastatic ductal carcinoma like a breast cancer in this, that usually that's not that difficult of a diagnosis especially if it's diffused like that and it extends to the surface. Here's another sclerosing epithelial neoplasm. And notice the stroma here. Can you tell the difference between this stroma and the one we just looked at in the MAC? See how fibrous this stroma is. These are more basophilic cells. There's calcification here. There may be some little small duct-like structures at the top of the calcification. This is",
"med_umls_ids": "[[{'entity': 'Metastatic ductal carcinoma', 'concept_id': 'C2698203', 'confidence': 0.8917744159698486}, {'entity': 'breast cancer', 'concept_id': 'C0006142', 'confidence': 0.9999999403953552}, {'entity': 'differentiated', 'concept_id': 'C0007589', 'confidence': 1.0}, {'entity': 'neoplasms', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'diffuse', 'concept_id': 'C0205219', 'confidence': 1.0}, {'entity': 'nature', 'concept_id': 'C0349590', 'confidence': 1.0}, {'entity': 'extension', 'concept_id': 'C0231448', 'confidence': 1.0}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}], [{'entity': 'Sclerosing', 'concept_id': 'C0036426', 'confidence': 0.833010733127594}, {'entity': 'epithelial neoplasms', 'concept_id': 'C1368683', 'confidence': 0.9999999403953552}, {'entity': 'fibrous stroma', 'concept_id': 'C1180207', 'confidence': 0.8035051226615906}, {'entity': 'calcification', 'concept_id': 'C0006660', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_129",
"caption_rating": "8"
},
{
"": "1006585",
"caption": "Presence of Brenner tumor in the ovary, which can be benign or show aggressive behavior and infiltrate ovarian stroma, leading to transitional cell carcinoma.",
"image_path": "3mRB9j0eyVM_image_0c4179d7-d7df-4f7a-9edc-be70f039efe7.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gynecologic', 'Hematopathology', 'Soft tissue']",
"roi_text": "['ovary', 'Brenner tumor', 'ovary', 'transitional cell carcinoma', 'papillary structures', 'transitional type cells', 'invasion']",
"noisy_text": " in the ovary and they do not show invasion you will call that this is a benign Brenner tumor. But when these cells these show aggressive behavior, they show ATPR and they infiltrate ovarian stroma then it will be named as transitional cell carcinoma. This is Brenner borderline tumor. Again here you can see the papillary structures that show stratification of the cells and the cells are of transitional type. So this is called Brenner borderline tumor because yet or still there is no invasion. When there is invasion of the cells here you can see there is marked ATPR in the urethelial cells or in the transitional cells and they show invasion",
"corrected_text": " in the ovary and they do not show invasion you will call that this is a benign Brenner tumor. But when these cells these show aggressive behavior, they show ATPR and they infiltrate ovarian stroma then it will be named as transitional cell carcinoma. This is Brenner borderline tumor. Again here you can see the papillary structures that show stratification of the cells and the cells are of transitional type. So this is called Brenner borderline tumor because yet or still there is no invasion. When there is invasion of the cells here you can see there is marked ATPR in the urothelial cells or in the transitional cells and they show invasion",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'Brenner tumor', 'concept_id': 'C0006160', 'confidence': 1.0}, {'entity': 'ovary', 'concept_id': 'C0029939', 'confidence': 1.0}, {'entity': 'benign', 'concept_id': 'C0205183', 'confidence': 1.0}, {'entity': 'aggressive behavior', 'concept_id': 'C0001807', 'confidence': 1.0}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'transitional', 'concept_id': 'C1182674', 'confidence': 1.0}, {'entity': 'cell carcinoma', 'concept_id': 'C1518174', 'confidence': 1.0}], [{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'Brenner borderline tumor', 'concept_id': 'C0334494', 'confidence': 0.9999999403953552}, {'entity': 'papillary structures', 'concept_id': 'C0030352', 'confidence': 0.7890171408653259}, {'entity': 'transitional', 'concept_id': 'C1182674', 'confidence': 1.0}, {'entity': 'invasion', 'concept_id': 'C1269955', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "960.0",
"id": "test_130",
"caption_rating": "9"
},
{
"": "1004746",
"caption": "Presence of at least two cell types with round to oval nuclei and faint eosinophilic to pale gray cytoplasm.",
"image_path": "8S4LeiO6Bbk_image_d28d47c0-0566-471c-9383-713c820a78ef.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['epithelial tumor', 'cytoplasm', 'vesicular chromatin pattern', 'lymphocytes', 'duct formation']",
"noisy_text": " If we move to higher power, we can see that we're dealing with an epithelial rather than a mosaicable tumor. We've got interconnected cords and strands. We have somewhat of a ribiform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of the cells are round to oval. They're fairly large. These cells have some faint eosinophilic to pale gray cytoplasm, although this cytoplasm is kind of difficult to see. Some of these cells have an evenly dispersed or vesicular chromatin pattern, and other nuclei are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and",
"corrected_text": " If we move to higher power, we can see that we're dealing with an epithelial rather than a mesenchymal tumor. We've got interconnected cords and strands. We have somewhat of a cribriform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of the cells are round to oval. They're fairly large. These cells have some faint eosinophilic to pale gray cytoplasm, although this cytoplasm is kind of difficult to see. Some of these cells have an evenly dispersed or vesicular chromatin pattern, and other nuclei are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'epithelial tumor', 'concept_id': 'C1368683', 'confidence': 0.9999999403953552}, {'entity': 'cords', 'concept_id': 'C0034869', 'confidence': 0.801885187625885}, {'entity': 'strands', 'concept_id': 'C0600383', 'confidence': 0.800572395324707}], [{'entity': 'Cribriform pattern', 'concept_id': 'C1333163', 'confidence': 1.0}, {'entity': 'loose', 'concept_id': 'C0205407', 'confidence': 1.0}, {'entity': 'edematous', 'concept_id': 'C0013604', 'confidence': 1.0}, {'entity': 'vascular stroma', 'concept_id': 'C0005847', 'confidence': 0.8046398758888245}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'cell types', 'concept_id': 'C0007634', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'eosinophilic', 'concept_id': 'C0333930', 'confidence': 1.0}, {'entity': 'pale', 'concept_id': 'C0030232', 'confidence': 1.0}, {'entity': 'gray cytoplasm', 'concept_id': 'C0010834', 'confidence': 0.8177905678749084}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'duct', 'concept_id': 'C0687028', 'confidence': 1.0}, {'entity': 'formation', 'concept_id': 'C0220781', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_131",
"caption_rating": "8"
},
{
"": "1008037",
"caption": "The lesion shows a collection of dilated vascular spaces lined by plump endothelial cells with papillary projections, indicating a vascular neoplasm with a biphasic pattern.",
"image_path": "8S4LeiO6Bbk_image_65252231-b45f-4d69-a856-883d8bb672e9.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['dilated vascular spaces', 'plump endothelial cells', 'papillary projections', 'extravasated erythrocytes', 'dilated vascular spaces', 'plump endothelial cells', 'papillary projections', 'extravasated erythrocytes']",
"noisy_text": " we can see that in the central portion of the lesion, we've got a collection of vascular spaces that are quite large or dilated. Many of these are lined by very plump kind of epithelioid or hobnailed endothelial cells, and some of them contain papillary projections that extend into the limina. If you look around, you can see these papillary projections. There are a few extravasated erythrocytes present within the stroma. So clearly, we've got this vascular neoplasma here with these dilated endothelial line spaces, but it's got kind of a bifasic pattern. Centrally, we've got these dilated vessels, but peripheral and beneath that zone, the vessels are somewhat more compressed. They're still lined by some of the plump endothelial cells. And in these various",
"corrected_text": " we can see that in the central portion of the lesion, we've got a collection of vascular spaces that are quite large or dilated. Many of these are lined by very plump kind of epithelioid or hobnailed endothelial cells, and some of them contain papillary projections that extend into the limina. If you look around, you can see these papillary projections. There are a few extravasated erythrocytes present within the stroma. So clearly, we've got this vascular neoplasm here with these dilated endothelial line spaces, but it's got kind of a biphasic pattern. Centrally, we've got these dilated vessels, but peripheral and beneath that zone, the vessels are somewhat more compressed. They're still lined by some of the plump endothelial cells. And in these various",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'collection', 'concept_id': 'C0600644', 'confidence': 1.0}, {'entity': 'dilated', 'concept_id': 'C0700124', 'confidence': 0.9999999403953552}, {'entity': 'vascular spaces', 'concept_id': 'C0225983', 'confidence': 0.819495439529419}, {'entity': 'plump', 'concept_id': 'C1836543', 'confidence': 0.7694027423858643}, {'entity': 'papillary projections', 'concept_id': 'C0016538', 'confidence': 0.7451471090316772}, {'entity': 'vascular neoplasm', 'concept_id': 'C0027668', 'confidence': 1.0}, {'entity': 'biphasic pattern', 'concept_id': 'C1332555', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_132",
"caption_rating": "9"
},
{
"": "1005564",
"caption": "Cylindromas are a close cousin of spear adenomas that also show differentiation towards the secretory gland.",
"image_path": "8S4LeiO6Bbk_image_8408bd75-b7f3-445a-bea2-27b09285f5d7.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['blue balls in the dermis', 'lymphocytes sprinkled throughout the tumor', 'tumor islands surrounded by a highland sheet', 'lymphocytes sprinkled throughout the tumor']",
"noisy_text": " findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and a sprinkling of lymphocytes in concert with ducts in the tumor, and an edematous stroma are diagnostic of spear adenoma. And of course, this is one of the glandular neoplasm that shows differentiation towards the secretory component of this white gland. So very nice example here of a spear adenoma. Same two cell types really can be seen in cylindromes as well. A close cousin of spear adenomas that also show differentiation towards the secretory gland. They generally lack, however, the lymphocytes sprinkled throughout the tumor. And of course, the tumor islands are surrounded by a highland sheet, but otherwise, the composition of the two tumors is similar. And it's not unusual at all to see tumors that show features of both types of neoplasms and a given biopsy. Moving on to slide number four. Slide number four is, was rather, a large punch biopsy. And I think this actually was two punch biopsies from one lesion, each one bisected. And",
"corrected_text": " findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and a sprinkling of lymphocytes in concert with ducts in the tumor, and an edematous stroma are diagnostic of spear adenoma. And of course, this is one of the glandular neoplasm that shows differentiation towards the secretory component of this white gland. So very nice example here of a spear adenoma. Same two cell types really can be seen in cylindromas as well. A close cousin of spear adenomas that also show differentiation towards the secretory gland. They generally lack, however, the lymphocytes sprinkled throughout the tumor. And of course, the tumor islands are surrounded by a highland sheet, but otherwise, the composition of the two tumors is similar. And it's not unusual at all to see tumors that show features of both types of neoplasms and a given biopsy. Moving on to slide number four. Slide number four is, was rather, a large punch biopsy. And I think this actually was two punch biopsies from one lesion, each one bisected. And",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'blue balls', 'concept_id': 'C0010520', 'confidence': 0.7417093515396118}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'cell types', 'concept_id': 'C0007634', 'confidence': 1.0}, {'entity': 'light', 'concept_id': 'C0023693', 'confidence': 0.9999999403953552}, {'entity': 'sprinkling', 'concept_id': 'C0439817', 'confidence': 0.7550094723701477}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'ducts', 'concept_id': 'C0687028', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'edematous stroma', 'concept_id': 'C1333376', 'confidence': 0.8675230145454407}, {'entity': 'diagnostic', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'spear adenoma', 'concept_id': 'C0001430', 'confidence': 0.7512055039405823}], [{'entity': 'Spear adenoma', 'concept_id': 'C0001430', 'confidence': 0.7512055039405823}, {'entity': 'glandular neoplasms', 'concept_id': 'C0205854', 'confidence': 1.0}, {'entity': 'differentiation', 'concept_id': 'C0007589', 'confidence': 1.0}, {'entity': 'secretory', 'concept_id': 'C1327616', 'confidence': 1.0}, {'entity': 'white gland', 'concept_id': 'C0007457', 'confidence': 0.7922286987304688}], [{'entity': 'Cylindromas', 'concept_id': 'C0010606', 'confidence': 0.9999998807907104}, {'entity': 'cousin', 'concept_id': 'C0337580', 'confidence': 1.0}, {'entity': 'spear adenomas', 'concept_id': 'C0001430', 'confidence': 0.7862440347671509}, {'entity': 'differentiation', 'concept_id': 'C0007589', 'confidence': 1.0}, {'entity': 'secretory gland', 'concept_id': 'C1327616', 'confidence': 0.8326038718223572}], [{'entity': 'Tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'neoplasms', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_133",
"caption_rating": "8"
},
{
"": "1007870",
"caption": "The basal cell markers are positive in the glands, indicating they are benign.",
"image_path": "iklRyY1nBIE_image_869c5468-faf3-4487-a43c-bbb6750545d5.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['The focus of interest', 'The glands with positive basal cell markers', 'The focus of interest', 'The glands with positive basal cell markers']",
"noisy_text": " And this is the focus of interest right here. So again, for the medical students who are in the audience, the pink cocktail is a combination of hemoglobin cytokeratin, P63, and P504S, also known as Amacar. P63 and hemoglobin cytokeratin highlight the basal cells. P63 is a nuclear stain, and the hemoglobin cytokeratin is more of a wispy kind of membrane on cytoplasmic stain. So as you can see, it's always important to look at the internal control. Any time you get a stain, you want to look at the glands you know are benign. You want to make sure the stain worked very well, because if the stain didn't work very well, that can get you in trouble when you're looking at the focus of interest. But if we come back to this particular case here, we can see that the stains worked very well. The basal cell markers are positive in the glands. We are comfortable or benign. The problem is when we come to this area we were looking at earlier, you can see that",
"corrected_text": " And this is the focus of interest right here. So again, for the medical students who are in the audience, the pink cocktail is a combination of hemoglobin cytokeratin, P63, and P504S, also known as Amacar. P63 and hemoglobin cytokeratin highlight the basal cells. P63 is a nuclear stain, and the hemoglobin cytokeratin is more of a wispy kind of membrane on cytoplasmic stain. So as you can see, it's always important to look at the internal control. Any time you get a stain, you want to look at the glands you know are benign. You want to make sure the stain worked very well, because if the stain didn't work very well, that can get you in trouble when you're looking at the focus of interest. But if we come back to this particular case here, we can see that the stains worked very well. The basal cell markers are positive in the glands. We are comfortable or benign. The problem is when we come to this area we were looking at earlier, you can see that",
"med_umls_ids": "[[{'entity': 'pink cocktail', 'concept_id': 'C0678420', 'confidence': 0.8575658798217773}, {'entity': 'combination', 'concept_id': 'C0205195', 'confidence': 1.0}, {'entity': 'hemoglobin cytokeratin', 'concept_id': 'C0010803', 'confidence': 0.7460406422615051}, {'entity': 'P63', 'concept_id': 'C1422009', 'confidence': 1.0}, {'entity': 'P504S', 'concept_id': 'C1172764', 'confidence': 0.9999999403953552}, {'entity': 'Amacar', 'concept_id': 'C3469830', 'confidence': 0.649845540523529}], [{'entity': 'P63', 'concept_id': 'C1422009', 'confidence': 1.0}, {'entity': 'hemoglobin cytokeratin', 'concept_id': 'C0010803', 'confidence': 0.7460406422615051}, {'entity': 'basal cells', 'concept_id': 'C0596155', 'confidence': 1.0}], [{'entity': 'internal control', 'concept_id': 'C0597937', 'confidence': 0.9999999403953552}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}], [{'entity': 'basal cell', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'markers', 'concept_id': 'C0181734', 'confidence': 0.890313982963562}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'benign', 'concept_id': 'C0205183', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_134",
"caption_rating": "8"
},
{
"": "1005790",
"caption": "Elastic cartilage is found in the external ear and the epiglottis.",
"image_path": "ib991vTA67A_image_16aa5ee3-f5c4-4aca-9da4-3d65198defc4.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Head and Neck']",
"roi_text": "['elastic cartilage', 'lacunas', 'chondrocytes', 'external ear', 'epiglottis', 'reticular connective tissue', 'epithelial tissue']",
"noisy_text": " the answer, this is elastic cartilage, you know it's a cartilage because you see the lacunas, so this is lacuna right here with the chondrocyte in it, where do you find elastic cartilage, think of the E's, elastic cartilage, external ear and the epiglottis, so elastic cartilage, external ear, epiglottis, that's where you're going to find elastic cartilage, that was number nineteen, number twenty, where do you, see this is a reticular connective tissue again, where do you find it, underneath all epithelial tissue, underneath all epithelial tissue, remember",
"corrected_text": " the answer, this is elastic cartilage, you know it's a cartilage because you see the lacunas, so this is lacuna right here with the chondrocyte in it, where do you find elastic cartilage, think of the E's, elastic cartilage, external ear and the epiglottis, so elastic cartilage, external ear, epiglottis, that's where you're going to find elastic cartilage, that was number nineteen, number twenty, where do you, see this is a reticular connective tissue again, where do you find it, underneath all epithelial tissue, underneath all epithelial tissue, remember",
"med_umls_ids": "[[{'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'examined', 'concept_id': 'C0332128', 'confidence': 1.0}, {'entity': 'elastic cartilage', 'concept_id': 'C0682559', 'confidence': 0.9999998807907104}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lacunas', 'concept_id': 'C1459585', 'confidence': 0.8563621044158936}, {'entity': 'chondrocytes', 'concept_id': 'C0225369', 'confidence': 1.0}], [{'entity': 'Elastic cartilage', 'concept_id': 'C0682559', 'confidence': 0.9999998807907104}, {'entity': 'external ear', 'concept_id': 'C0013453', 'confidence': 1.0}, {'entity': 'epiglottis', 'concept_id': 'C0014540', 'confidence': 0.9999999403953552}], [{'entity': 'Reticular', 'concept_id': 'C0439739', 'confidence': 1.0}, {'entity': 'connective tissue', 'concept_id': 'C0009780', 'confidence': 1.0}, {'entity': 'epithelial tissue', 'concept_id': 'C0014609', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1152.0",
"id": "test_135",
"caption_rating": "7"
},
{
"": "1008699",
"caption": "The biopsy is from an acral site and shows a dome-shaped papule.",
"image_path": "8S4LeiO6Bbk_image_d73237ea-0389-4d09-a0bf-a7cf76772156.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['dome-shaped papule', 'acral site', 'thick stratum corneum', 'absence of hair follicles', 'fibrovascular core', 'nerve fascicles', 'spindle-shaped cells', 'S100', 'SOX10', 'rudimentary supernumerary digit', 'dome-shaped papule', 'acral site', 'thick stratum corneum', 'absence of hair follicles', 'fibrovascular core', 'nerve fascicles', 'spindle-shaped cells', 'S100', 'SOX10', 'rudimentary supernumerary digit']",
"noisy_text": " we've got a dome-shaped papule and that the biopsy is from an acral site. Notice that we've got a very very thick stratum corneum and a marked to virtual absence of hair follicles within the specimen. We do have kind of this fibrovascular core and of course in the center of the fibrovascular core here we've got several well-defined nerve fascicles and the spindled cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions",
"corrected_text": " we've got a dome-shaped papule and that the biopsy is from an acral site. Notice that we've got a very very thick stratum corneum and a marked to virtual absence of hair follicles within the specimen. We do have kind of this fibrovascular core and of course in the center of the fibrovascular core here we've got several well-defined nerve fascicles and the spindle cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions",
"med_umls_ids": "[[{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'acral site', 'concept_id': 'C0439746', 'confidence': 0.717435359954834}, {'entity': 'dome-shaped papule', 'concept_id': 'C1711316', 'confidence': 0.752353847026825}], [{'entity': 'specimen', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'stratum corneum', 'concept_id': 'C0221921', 'confidence': 1.0}, {'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'hair follicles', 'concept_id': 'C0221971', 'confidence': 0.9999998807907104}], [{'entity': 'fibrovascular', 'concept_id': 'C0392759', 'confidence': 1.0}, {'entity': 'nerve fascicles', 'concept_id': 'C1185741', 'confidence': 0.8332967758178711}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'S100', 'concept_id': 'C3273837', 'confidence': 1.0}, {'entity': 'SOX10', 'concept_id': 'C1420317', 'confidence': 0.9999998807907104}, {'entity': 'neural tumor', 'concept_id': 'C1334956', 'confidence': 1.0}], [{'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'rudimentary supernumerary digit', 'concept_id': 'C0152427', 'confidence': 0.8142021894454956}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_136",
"caption_rating": "7"
},
{
"": "1007440",
"caption": "The patient had a history of uveitis with characteristic features that were good for sarcoidosis.",
"image_path": "sDFjOtMAYrk_image_64ecfd50-c3b0-487d-b33a-10de6f769850.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['uveitis with characteristic features', 'granulomas in sarcoidosis and Crohn\u2019s disease', 'uveitis with characteristic features', 'granulomas in sarcoidosis and Crohn\u2019s disease']",
"noisy_text": " patient had sarcoid. So I said, this is probably not IBD, clinicians came down, we want to look at the biopsy, of course. It turns out that they went back and talked to the patient. The patient has a history of uveitis with characteristic features that were good for sarcoidosis. Nobody knew about they treated the patient for sarcoid, re-biopsied the patient. And he was fine. There were no more granulomas on multiple repeat biopsies. And now compare those grannies with the grannies in Crohn's. So here's a giant cell right there, but there was a better one right there. So they're like kind of",
"corrected_text": " patient had sarcoid. So I said, this is probably not IBD, clinicians came down, we want to look at the biopsy, of course. It turns out that they went back and talked to the patient. The patient has a history of uveitis with characteristic features that were good for sarcoidosis. Nobody knew about they treated the patient for sarcoid, re-biopsied the patient. And he was fine. There were no more granulomas on multiple repeat biopsies. And now compare those grannies with the grannies in Crohn's. So here's a giant cell right there, but there was a better one right there. So they're like kind of",
"med_umls_ids": "[[{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'suspected', 'concept_id': 'C0332147', 'confidence': 1.0}, {'entity': 'IBD', 'concept_id': 'C0021390', 'confidence': 1.0}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'history', 'concept_id': 'C0019664', 'confidence': 1.0}, {'entity': 'uveitis', 'concept_id': 'C0042164', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'treated', 'concept_id': 'C1522326', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'biopsies', 'concept_id': 'C0005558', 'confidence': 1.0}, {'entity': 'granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}], [{'entity': 'Comparison', 'concept_id': 'C1707455', 'confidence': 1.0}, {'entity': 'granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'Crohn\u2019s disease', 'concept_id': 'C0010346', 'confidence': 0.8916962146759033}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_137",
"caption_rating": "7"
},
{
"": "1008700",
"caption": "The specimen has a very thick stratum corneum and a marked absence of hair follicles.",
"image_path": "8S4LeiO6Bbk_image_d73237ea-0389-4d09-a0bf-a7cf76772156.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['dome-shaped papule', 'acral site', 'thick stratum corneum', 'absence of hair follicles', 'fibrovascular core', 'nerve fascicles', 'spindle-shaped cells', 'S100', 'SOX10', 'rudimentary supernumerary digit', 'dome-shaped papule', 'acral site', 'thick stratum corneum', 'absence of hair follicles', 'fibrovascular core', 'nerve fascicles', 'spindle-shaped cells', 'S100', 'SOX10', 'rudimentary supernumerary digit']",
"noisy_text": " we've got a dome-shaped papule and that the biopsy is from an acral site. Notice that we've got a very very thick stratum corneum and a marked to virtual absence of hair follicles within the specimen. We do have kind of this fibrovascular core and of course in the center of the fibrovascular core here we've got several well-defined nerve fascicles and the spindled cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions",
"corrected_text": " we've got a dome-shaped papule and that the biopsy is from an acral site. Notice that we've got a very very thick stratum corneum and a marked to virtual absence of hair follicles within the specimen. We do have kind of this fibrovascular core and of course in the center of the fibrovascular core here we've got several well-defined nerve fascicles and the spindle cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions",
"med_umls_ids": "[[{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'acral site', 'concept_id': 'C0439746', 'confidence': 0.717435359954834}, {'entity': 'dome-shaped papule', 'concept_id': 'C1711316', 'confidence': 0.752353847026825}], [{'entity': 'specimen', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'stratum corneum', 'concept_id': 'C0221921', 'confidence': 1.0}, {'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'hair follicles', 'concept_id': 'C0221971', 'confidence': 0.9999998807907104}], [{'entity': 'fibrovascular', 'concept_id': 'C0392759', 'confidence': 1.0}, {'entity': 'nerve fascicles', 'concept_id': 'C1185741', 'confidence': 0.8332967758178711}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'S100', 'concept_id': 'C3273837', 'confidence': 1.0}, {'entity': 'SOX10', 'concept_id': 'C1420317', 'confidence': 0.9999998807907104}, {'entity': 'neural tumor', 'concept_id': 'C1334956', 'confidence': 1.0}], [{'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'rudimentary supernumerary digit', 'concept_id': 'C0152427', 'confidence': 0.8142021894454956}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_138",
"caption_rating": "8"
},
{
"": "1006988",
"caption": "Histopathological examination of prostate cancer with staining for nuclear and membranous wispy cytoplasmic stain, hemoglobin cytokeratin, and predominantly negative racemase.",
"image_path": "iklRyY1nBIE_image_5b0ad93d-afea-4b34-9971-f890eee96412.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['Prostate cancer with aberrant P63 staining expression.']",
"noisy_text": " Again, you want to look at your internal control. These are the glands that were comfortable or benign. You can see they're staining for both nuclear stain and membranous wispy cytoplasmic stain, which is the hemoglobin cytokeratin. In this baccalaureate case, the racemase was predominantly negative. There's a hint of staining in areas, but it's predominantly negative. What is striking, what is very striking, is the fact that the P63 is diffusely positive, which they found very odd. And so this is a very, very fascinating case of prostatic adenocarcinoma with aberrant P63 expression, or what some people call P63 prostate prostate cancer. And I'll show you, this is the index case, but I'll show you a few other cases. Because it's a very, very fascinating, it's an",
"corrected_text": " Again, you want to look at your internal control. These are the glands that were comfortable or benign. You can see they're staining for both nuclear stain and membranous wispy cytoplasmic stain, which is the hemoglobin cytokeratin. In this baccalaureate case, the racemase was predominantly negative. There's a hint of staining in areas, but it's predominantly negative. What is striking, what is very striking, is the fact that the P63 is diffusely positive, which they found very odd. And so this is a very, very fascinating case of prostatic adenocarcinoma with aberrant P63 expression, or what some people call P63 prostate prostate cancer. And I'll show you, this is the index case, but I'll show you a few other cases. Because it's a very, very fascinating, it's an",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'examination', 'concept_id': 'C0031809', 'confidence': 1.0}, {'entity': 'prostate cancer', 'concept_id': 'C0376358', 'confidence': 1.0}, {'entity': 'staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'nuclear', 'concept_id': 'C0521447', 'confidence': 1.0}, {'entity': 'membranous', 'concept_id': 'C0025255', 'confidence': 1.0}, {'entity': 'wispy cytoplasmic stain', 'concept_id': 'C0010834', 'confidence': 0.6738394498825073}, {'entity': 'hemoglobin cytokeratin', 'concept_id': 'C0010803', 'confidence': 0.7460406422615051}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'racemase', 'concept_id': 'C0034503', 'confidence': 1.0}], [{'entity': 'Diffuse positive P63 staining', 'concept_id': 'C0205219', 'confidence': 0.5406208634376526}, {'entity': 'expression', 'concept_id': 'C0017262', 'confidence': 0.9999998807907104}, {'entity': 'prostatic adenocarcinoma', 'concept_id': 'C0007112', 'confidence': 1.0}, {'entity': 'P63 prostate cancer', 'concept_id': 'C0376358', 'confidence': 0.7053087949752808}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_139",
"caption_rating": "8"
},
{
"": "1008634",
"caption": "Specimen appears well-circumscribed but has some features that raise suspicion for malignancy, such as being bottombulky and asymmetrical.",
"image_path": "LlPaENuqzVQ_image_50611b7f-cef4-4bbb-855a-ac0e7ebc59e9.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['malignant', 'malignant', 'neoplasm', 'dermis', 'eosinophilic ball cells', 'malignant', 'benign', 'necrosis']",
"noisy_text": " OK, let's give this one a go. Yeah, I can do this one. So looks like we have a, I mean, I'm thinking this is probably malignant. Oh, sorry, it's not inflammatory. It's some proliferation of cells here. And this is likely, it's a eosinophilic, well-encapsulated. So you think it's a neoplasm? Yeah, it's a neoplastic process that it's, yeah. So I'm seeing eosinophilic ball cells in the dermis. I don't think that I can say much more at this point. You can, you can. So do you think it's epithelial or non-epithelial? It's probably not epithelial. Good, good, good. And you know, at low power, that's fine. You can say probably this, because you're going to confirm it when you go to higher magnitudes. That's perfectly fine. At low power, sometimes you can make an instant diagnosis. If you see molluscum bodies at low power, you just move on to the next case. Or you see herpes varus, you're gone, you're finished. You don't have to waste time on it anymore. But if it's something like this, you say, well, yeah, it looks like it's probably non-epithelial. Sometimes you can get spindle-shaped cells in an epithelial neoplasm, like a squamous cell, spindle cell, squamous cell. So we're not sure, but you're right. At low power, it seems like it's probably going to be non-epithelial. Certainly doesn't look like any typical epithelial structure. And it's interesting. You said it looks kind of well-circumscribed. I agree. But it's got a, this is a pretty low power view, and it's a pretty big specimen. So it's large, and it's kind of bottom-heavy. So you said at low power, you thought it was malignant. So why did you say malignant? Sorry, I meant neoplastic. I don't think, I mean, it looks very well-capsulated, and it looks like it's probably completely removed. So I actually, I favor benign, but it might be benign. Yeah, I agree, it could be benign. But it does have a couple of features a little bit weird. It's bottom-heavy, which that kind of makes you say, well, you be careful, because bottom-heavy neoplasm can sometimes be malignant, even though they kind of look well-circumscribed. It's a little bit asymmetrical. We draw a line down the middle of it. I mean, this little piece over here is kind of sticking out versus over here. So it may be benign, because it seems to be well-circumscribed, but it's got a couple of criteria that we wonder at low power. Maybe we're going to make sure that it's not malignant. This may even be some necrosis on moss in here, which is another feature of malignant. So we're going to have magnification. Let's see what",
"corrected_text": " OK, let's give this one a go. Yeah, I can do this one. So looks like we have a, I mean, I'm thinking this is probably malignant. Oh, sorry, it's not inflammatory. It's some proliferation of cells here. And this is likely, it's a eosinophilic, well-encapsulated. So you think it's a neoplasm? Yeah, it's a neoplastic process that it's, yeah. So I'm seeing eosinophilic ball cells in the dermis. I don't think that I can say much more at this point. You can, you can. So do you think it's epithelial or non-epithelial? It's probably not epithelial. Good, good, good. And you know, at low power, that's fine. You can say probably this, because you're going to confirm it when you go to higher magnitudes. That's perfectly fine. At low power, sometimes you can make an instant diagnosis. If you see molluscum bodies at low power, you just move on to the next case. Or you see herpes varus, you're gone, you're finished. You don't have to waste time on it anymore. But if it's something like this, you say, well, yeah, it looks like it's probably non-epithelial. Sometimes you can get spindle-shaped cells in an epithelial neoplasm, like a squamous cell, spindle cell, squamous cell. So we're not sure, but you're right. At low power, it seems like it's probably going to be non-epithelial. Certainly doesn't look like any typical epithelial structure. And it's interesting. You said it looks kind of well-circumscribed. I agree. But it's got a, this is a pretty low power view, and it's a pretty big specimen. So it's large, and it's kind of bottombulky. So you said at low power, you thought it was malignant. So why did you say malignant? Sorry, I meant neoplastic. I don't think, I mean, it looks very well-capsulated, and it looks like it's probably completely removed. So I actually, I favor benign, but it might be benign. Yeah, I agree, it could be benign. But it does have a couple of features a little bit weird. It's bottombulky, which that kind of makes you say, well, you be careful, because bottombulky neoplasm can sometimes be malignant, even though they kind of look well-circumscribed. It's a little bit asymmetrical. We draw a line down the middle of it. I mean, this little piece over here is kind of sticking out versus over here. So it may be benign, because it seems to be well-circumscribed, but it's got a couple of criteria that we wonder at low power. Maybe we're going to make sure that it's not malignant. This may even be some necrosis on moss in here, which is another feature of malignant. So we're going to have magnification. Let's see what",
"med_umls_ids": "[[{'entity': 'neoplastic process', 'concept_id': 'C0027671', 'confidence': 1.0}, {'entity': 'eosinophilic ball cells', 'concept_id': 'C0682547', 'confidence': 0.8429232835769653}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}], [{'entity': 'Uncertain', 'concept_id': 'C0087130', 'confidence': 0.9999998807907104}, {'entity': 'neoplasm', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'epithelial', 'concept_id': 'C0221908', 'confidence': 1.0}, {'entity': 'non-epithelial', 'concept_id': 'C0809966', 'confidence': 0.7444443106651306}], [{'entity': 'Specimen', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'well-circumscribed', 'concept_id': 'C1707398', 'confidence': 0.9430561065673828}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'suspicion', 'concept_id': 'C0242114', 'confidence': 1.0}, {'entity': 'malignancy', 'concept_id': 'C0006826', 'confidence': 1.0}, {'entity': 'bottombulky', 'concept_id': 'C1511276', 'confidence': 0.5303326845169067}, {'entity': 'asymmetrical', 'concept_id': 'C0332514', 'confidence': 1.0}], [{'entity': 'magnification', 'concept_id': 'C5197828', 'confidence': 0.9129886031150818}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_140",
"caption_rating": "8"
},
{
"": "1007971",
"caption": "STOMPs can recur and may progress to prostatic stroma of sarcoma.",
"image_path": "iklRyY1nBIE_image_25025022-8442-4585-8463-496487442b19.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['basal cell hyperplasia', 'infiltrating between benign glands', 'STOMP', 'prostatic stroma of sarcoma', 'HMB45 melanin', 'S100', 'STAT6']",
"noisy_text": " Something else you may have observed with this case is the fact that it's not just a stroma process. It looks like there's something else going on in the glands, too. And in the glands, it's almost like there's a crosstalk between the stroma process and the glands. The glands are benign, but they actually have what looks like basal cell hyperplasia in areas. And that's not uncommon with this entity. It is not unusual to have this entity, actually, with basal cell hyperplasia. The other observation I want to bring to your attention is the fact that this process is going in between benign glands, which means that it's almost respecting the benign glands next door. Because there are a number of processes that would destroy the adjacent benign glands and basically push them aside. But this process actually respects the benign glands, in quotes, and is actually going in between them, infiltrating in between them. And that's a clue to the diagnosis. Because as I hinted earlier, when you talk of tumors of the specialized prosthetic stroma, there are two main entities you think about. One is the so-called STOMP, stromal tumor of unsaturated malignant potential. And the other entity at the other extreme is the so-called prosthetic stroma of sarcoma. Some argue that there's some relationship between both of them that are in the spectrum. But what you're looking at right now in this case, based on what I've shown you, this type of atypia, it almost looks simplistic. It has this degenerative type of look to it. We are not seeing mitotic activity. For something this ugly or that looks this nasty, you'll expect to see necrosis, mitotic activity, and even destruction of the adjacent glands. But we're not seeing that. And that's kind of a perfect picture for so-called STOMP, stromal tumor of unsaturated malignant potential. As I said earlier, there's a relationship between this entity and prosthetic stroma of sarcoma. To start with, STOMPs can recur. About 15% of STOMPs can recur months or years after the initial resection. But about 15% to 20% of STOMPs may progress or may be associated with adjacent prosthetic stroma of sarcoma. So that's a very important thing to know. Because STOMP itself, as the name implies, is of unsaturated malignant potential. So it should not be downplayed. Because some of you may ask me, how do I sign all these cases? It's very important in your comments to document what I just said, that about 15% of these, if it's just STOMP is here on the H&E, nothing else, it's important to document that about 15% would recur. And more importantly, it's important to document that about 15% to 20% of these may be associated with or progress to prosthetic stroma of sarcoma. So it's not a case of they excise this and they leave the patient alone. They need to follow up these patients very closely. So that's very important to document in the report. So some of you may ask, OK, so what stains do we do for these cases? Obviously, you want to exclude a number of things. We talked about melanoma and other things. So you want to exclude those. So obviously, HMB45 melanin, those will be negative. Vimentin, which nobody uses anymore, is actually positive in this entity. PR could also be positive in this entity. Plus or minus CD34, plus or minus Desmin SMA, plus or minus ER may be positive, but it's usually negative. The pertinent negative stains are S100. I talked about the melanoma markers. And STAT6 is also negative. So it's very important to know that. So this is a stromal tumor of uncertain malignant potential. There have been a number of names for this entity over the years.",
"corrected_text": " Something else you may have observed with this case is the fact that it's not just a stroma process. It looks like there's something else going on in the glands, too. And in the glands, it's almost like there's a crosstalk between the stroma process and the glands. The glands are benign, but they actually have what looks like basal cell hyperplasia in areas. And that's not uncommon with this entity. It is not unusual to have this entity, actually, with basal cell hyperplasia. The other observation I want to bring to your attention is the fact that this process is going in between benign glands, which means that it's almost respecting the benign glands next door. Because there are a number of processes that would destroy the adjacent benign glands and basically push them aside. But this process actually respects the benign glands, in quotes, and is actually going in between them, infiltrating in between them. And that's a clue to the diagnosis. Because as I hinted earlier, when you talk of tumors of the specialized prosthetic stroma, there are two main entities you think about. One is the so-called STOMP, stromal tumor of unsaturated malignant potential. And the other entity at the other extreme is the so-called prosthetic stroma of sarcoma. Some argue that there's some relationship between both of them that are in the spectrum. But what you're looking at right now in this case, based on what I've shown you, this type of atypia, it almost looks simplistic. It has this degenerative type of look to it. We are not seeing mitotic activity. For something this ugly or that looks this nasty, you'expect to see necrosis, mitotic activity, and even destruction of the adjacent glands. But we're not seeing that. And that's kind of a perfect picture for so-called STOMP, stromal tumor of unsaturated malignant potential. As I said earlier, there's a relationship between this entity and prosthetic stroma of sarcoma. To start with, STOMPs can recur. About 15% of STOMPs can recur months or years after the initial resection. But about 15% to 20% of STOMPs may progress or may be associated with adjacent prosthetic stroma of sarcoma. So that's a very important thing to know. Because STOMP itself, as the name implies, is of unsaturated malignant potential. So it should not be downplayed. Because some of you may ask me, how do I sign all these cases? It's very important in your comments to document what I just said, that about 15% of these, if it's just STOMP is here on the H&E, nothing else, it's important to document that about 15% would recur. And more importantly, it's important to document that about 15% to 20% of these may be associated with or progress to prosthetic stroma of sarcoma. So it's not a case of they excise this and they leave the patient alone. They need to follow up these patients very closely. So that's very important to document in the report. So some of you may ask, OK, so what stains do we do for these cases? Obviously, you want to exclude a number of things. We talked about melanoma and other things. So you want to exclude those. So obviously, HMB45 melanin, those will be negative. Vimentin, which nobody uses anymore, is actually positive in this entity. PR could also be positive in this entity. Plus or minus CD34, plus or minus Desmin SMA, plus or minus ER may be positive, but it's usually negative. The pertinent negative stains are S100. I talked about the melanoma markers. And STAT6 is also negative. So it's very important to know that. So this is a stromal tumor of uncertain malignant potential. There have been a number of names for this entity over the years.",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'basal cell', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'benign glands', 'concept_id': 'C1301287', 'confidence': 0.726940393447876}, {'entity': 'entity', 'concept_id': 'C1551338', 'confidence': 1.0}], [{'entity': 'process', 'concept_id': 'C1184743', 'confidence': 1.0}, {'entity': 'infiltrating', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'benign glands', 'concept_id': 'C1301287', 'confidence': 0.726940393447876}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'atypia', 'concept_id': 'C0741302', 'confidence': 0.9999999403953552}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'consistent with', 'concept_id': 'C0332290', 'confidence': 1.0}, {'entity': 'STOMP', 'concept_id': 'C0056167', 'confidence': 0.6245664358139038}, {'entity': 'stromal tumor', 'concept_id': 'C0879615', 'confidence': 1.0}, {'entity': 'malignant', 'concept_id': 'C0205282', 'confidence': 1.0}, {'entity': 'potential', 'concept_id': 'C3245505', 'confidence': 1.0}], [{'entity': 'STOMPs', 'concept_id': 'C0577018', 'confidence': 0.6140404343605042}, {'entity': 'recur', 'concept_id': 'C0034897', 'confidence': 0.9999999403953552}, {'entity': 'progress', 'concept_id': 'C1272688', 'confidence': 1.0}, {'entity': 'prostatic stroma', 'concept_id': 'C1521760', 'confidence': 0.9999999403953552}, {'entity': 'sarcoma', 'concept_id': 'C1261473', 'confidence': 1.0}], [{'entity': 'Stains', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'entities', 'concept_id': 'C0424215', 'confidence': 0.7521668672561646}, {'entity': 'HMB45', 'concept_id': 'C1440756', 'confidence': 1.0}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}, {'entity': 'S100', 'concept_id': 'C3273837', 'confidence': 1.0}, {'entity': 'STAT6', 'concept_id': 'C0297890', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_141",
"caption_rating": "8"
},
{
"": "1008547",
"caption": "There are localized and diffuse types of tenosynovial giant cell tumor, both with balanced translocations involving the CSF1R gene.",
"image_path": "j_rG5XPImFQ_image_ed964c45-9360-49f2-9c3d-5c51a6c87885.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Hematopathology', 'Breast pathology']",
"roi_text": "['ladybug or ladybird cells', 'CSF1R gene', 'tenosynovial giant cell tumor', 'giant cell tumor of soft tissue', 'peripheral ossification']",
"noisy_text": " Often, the hemosiderin likes to accumulate in mononuclear tumor cells around the periphery. These are referred to as ladybug or ladybird cells. So far, I've only talked about localized tenosynovial giant cell tumor. However, there is also a diffuse type. This type commonly arises in the larger joints and carries a risk of significant morbidity, since negative margins can be difficult to obtain. Both the localized and diffuse types of tenosynovial giant cell tumor have balanced translocations involving the chromosomal region of 1p13, which includes the CSF1 gene. Overexpression of CSF1 by tumor cells is what is thought to cause the recruitment of osteoclasts like giant cells. There are also giant cell tumors arising in the soft tissue and bone, and I'm going to talk a little bit about those. Giant cell tumor of soft tissue arises in the superficial soft tissues, most commonly in the arm, thigh, and calf. They may also have a rim of peripheral ossification, so myocytosis ossificans, which I've talked about in a previous video, may enter the differential based on the imaging findings. These lesions do not have any characteristic molecular alterations. Giant cell",
"corrected_text": " Often, the hemosiderin likes to accumulate in mononuclear tumor cells around the periphery. These are referred to as ladybug or ladybird cells. So far, I've only talked about localized tenosynovial giant cell tumor. However, there is also a diffuse type. This type commonly arises in the larger joints and carries a risk of significant morbidity, since negative margins can be difficult to obtain. Both the localized and diffuse types of tenosynovial giant cell tumor have balanced translocations involving the CSF1R gene the chromosomal region of 1p13, which includes the CSF1 gene. Overexpression of CSF1 by tumor cells is what is thought to cause the recruitment of osteoclasts like giant cells. There are also giant cell tumors arising in the soft tissue and bone, and I'm going to talk a little bit about those. Giant cell tumor of soft tissue arises in the superficial soft tissues, most commonly in the arm, thigh, and calf. They may also have a rim of peripheral ossification, so myositis ossificans, which I've talked about in a previous video, may enter the differential based on the imaging findings. These lesions do not have any characteristic molecular alterations. Giant cell",
"med_umls_ids": "[[{'entity': 'Hemosiderin', 'concept_id': 'C0019113', 'confidence': 1.0}, {'entity': 'accumulates', 'concept_id': 'C4055506', 'confidence': 0.8533105254173279}, {'entity': 'mononuclear tumor cells', 'concept_id': 'C0806987', 'confidence': 0.8775115013122559}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'ladybug', 'concept_id': 'C0886269', 'confidence': 1.0}, {'entity': 'ladybird cells', 'concept_id': 'C0998434', 'confidence': 0.736539363861084}], [{'entity': 'localized', 'concept_id': 'C0392752', 'confidence': 1.0}, {'entity': 'diffuse', 'concept_id': 'C0205219', 'confidence': 1.0}, {'entity': 'tenosynovial giant cell tumor', 'concept_id': 'C1318543', 'confidence': 1.0}, {'entity': 'balanced', 'concept_id': 'C0205415', 'confidence': 1.0}, {'entity': 'translocations', 'concept_id': 'C0040715', 'confidence': 1.0}, {'entity': 'CSF1R gene', 'concept_id': 'C0879468', 'confidence': 1.0}], [{'entity': 'Giant cell tumor', 'concept_id': 'C0017525', 'confidence': 1.0}, {'entity': 'soft tissue', 'concept_id': 'C0225317', 'confidence': 0.9999999403953552}, {'entity': 'superficial', 'concept_id': 'C0205124', 'confidence': 1.0}, {'entity': 'soft tissues', 'concept_id': 'C0225317', 'confidence': 1.0}, {'entity': 'arm', 'concept_id': 'C0003798', 'confidence': 1.0}, {'entity': 'thigh', 'concept_id': 'C0039866', 'confidence': 1.0}, {'entity': 'calf', 'concept_id': 'C0230445', 'confidence': 1.0}, {'entity': 'rim', 'concept_id': 'C1308727', 'confidence': 1.0}, {'entity': 'peripheral ossification', 'concept_id': 'C0029433', 'confidence': 0.7698169350624084}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_142",
"caption_rating": "7"
},
{
"": "1006348",
"caption": "Trichilemmal cyst biopsy specimen on slide number seven.",
"image_path": "8S4LeiO6Bbk_image_89afc7b2-8d75-4b3c-9eff-ab85550d9c16.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['nerve fascicles', 'spindle-shaped cells', 'rudimentary supernumerary digit', 'ulnar aspect of the fifth digit', 'acquired digital fibroma', 'acquired digital fibrokeratoma', 'trichilemmal cyst', 'nerve fascicles', 'spindle-shaped cells', 'rudimentary supernumerary digit', 'ulnar aspect of the fifth digit', 'acquired digital fibroma', 'acquired digital fibrokeratoma', 'trichilemmal cyst']",
"noisy_text": " core here we've got several well-defined nerve fascicles and the spindled cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions of course tend to occur along the ulnar eye aspect of the fifth digit. They're not infrequently bilateral and the key differential here of course is an acquired digital fibroma or an acquired digital fibrocarotoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if",
"corrected_text": " core here we've got several well-defined nerve fascicles and the spindle cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions of course tend to occur along the ulnar eye aspect of the fifth digit. They're not infrequently bilateral and the key differential here of course is an acquired digital fibroma or an acquired digital fibrokeratoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if",
"med_umls_ids": "[[{'entity': 'Well-defined nerve fascicles', 'concept_id': 'C1185741', 'confidence': 0.5682494640350342}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'S100', 'concept_id': 'C3273837', 'confidence': 1.0}, {'entity': 'SOX10', 'concept_id': 'C1420317', 'confidence': 0.9999998807907104}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'rudimentary supernumerary digit', 'concept_id': 'C0152427', 'confidence': 0.8142021894454956}], [{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'ulnar', 'concept_id': 'C0442044', 'confidence': 1.0}, {'entity': 'aspect', 'concept_id': 'C1547011', 'confidence': 1.0}, {'entity': 'fifth digit', 'concept_id': 'C0230403', 'confidence': 0.912693440914154}, {'entity': 'bilateral', 'concept_id': 'C0238767', 'confidence': 1.0}], [{'entity': 'differential diagnosis', 'concept_id': 'C0011906', 'confidence': 1.0}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}, {'entity': 'digital fibroma', 'concept_id': 'C4538745', 'confidence': 0.8997364640235901}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}], [{'entity': 'Trichilemmal cyst', 'concept_id': 'C2266788', 'confidence': 1.0}, {'entity': 'biopsy specimen', 'concept_id': 'C0677862', 'confidence': 1.0}, {'entity': 'slide number', 'concept_id': 'C3828004', 'confidence': 0.8261933326721191}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_143",
"caption_rating": "8"
},
{
"": "1007908",
"caption": "The presence of a large cellular fibrohistiocytic infiltrate with collagen trapping and ring siderophages is indicative of a hemosiderotic or aneurysmal type of dermatofibroma, also known as a sclerosing hemangioma variant of a dermatofibroma. These lesions have a tendency to persist or recur if incompletely excised.",
"image_path": "8S4LeiO6Bbk_image_4e0449f7-f5a1-41db-ba0e-90731b4390d7.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Large cellular fibrohistiocytic infiltrate with collagen trapping and ring siderophages', 'Hemosiderotic or aneurysmal type of dermatofibroma', 'Punch biopsy specimen', 'Large cellular fibrohistiocytic infiltrate with collagen trapping and ring siderophages', 'Hemosiderotic or aneurysmal type of dermatofibroma', 'Punch biopsy specimen', 'Large cellular fibrohistiocytic infiltrate with collagen trapping and ring siderophages', 'Hemosiderotic or aneurysmal type of dermatofibroma', 'Punch biopsy specimen']",
"noisy_text": " know, we're not seeing any necrosis or an appreciable number of mitotic figures. And this large cellular fibrohystic-acidic infiltrate, again with the collagen trapping and ring siderophages out of the periphery, seems to be compressing the fat. And the constellation of features in these sections is pathognomonic, of course, or a hemociderotic or aneurysmal type of dermatofibroma, also known as a sclerosing hemangioma variant of a dermatofibroma. This is a type of cellular dermatofibroma. These lesions can get quite large and if incompletely excised do have a tendency to persist or recur. So good idea to completely excise these because they're certainly not going to go away on their own. A classic example, very commonly asked on boards and usually spoilers that you could expect in a question given this slide would include things like a blue nevus or melanoma or even nodular cap issues. So be familiar with the features of the hemociderotic variant of a dermatofibroma. Moving on to slide number five. This was kind of a cool case. We have a bisected punch biopsy specimen here. If we move into higher power, we can see that the epidermis",
"corrected_text": " know, we're not seeing any necrosis or an appreciable number of mitotic figures. And this large cellular fibrohystic-acidic infiltrate, again with the collagen trapping and ring siderophages out of the periphery, seems to be compressing the fat. And the constellation of features in these sections is pathognomonic, of course, or a hemosiderotic or aneurysmal type of dermatofibroma, also known as a sclerosing hemangioma variant of a dermatofibroma. This is a type of cellular dermatofibroma. These lesions can get quite large and if incompletely excised do have a tendency to persist or recur. So good idea to completely excise these because they're certainly not going to go away on their own. A classic example, very commonly asked on boards and usually spoilers that you could expect in a question given this slide would include things like a blue nevus or melanoma or even nodular cap issues. So be familiar with the features of the hemosiderotic variant of dermatofibroma of a dermatofibroma. Moving on to slide number five. This was kind of a cool case. We have a bisected punch biopsy specimen here. If we move into higher power, we can see that the epidermis",
"med_umls_ids": "[[{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'cellular fibrohistiocytic infiltrate', 'concept_id': 'C0019618', 'confidence': 0.7253735065460205}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'trapping', 'concept_id': 'C0282665', 'confidence': 0.8904784917831421}, {'entity': 'ring siderophages', 'concept_id': 'C1136253', 'confidence': 0.6553963422775269}, {'entity': 'hemosiderotic', 'concept_id': 'C0019114', 'confidence': 0.7758374810218811}, {'entity': 'aneurysmal type', 'concept_id': 'C0439651', 'confidence': 0.8459930419921875}, {'entity': 'dermatofibroma', 'concept_id': 'C0002991', 'confidence': 1.0}, {'entity': 'sclerosing', 'concept_id': 'C0036426', 'confidence': 0.833010733127594}, {'entity': 'hemangioma', 'concept_id': 'C0018916', 'confidence': 1.0}, {'entity': 'variant', 'concept_id': 'C0205419', 'confidence': 1.0}, {'entity': 'dermatofibroma', 'concept_id': 'C0002991', 'confidence': 1.0}, {'entity': 'lesions', 'concept_id': 'C0221198', 'confidence': 1.0}, {'entity': 'excised', 'concept_id': 'C1444670', 'confidence': 0.7215964794158936}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_144",
"caption_rating": "9"
},
{
"": "1006801",
"caption": "The cells in the epidermis have a pale to clear appearance due to increased glycogen.",
"image_path": "yGCjnNbC7Qs_image_ba43aac1-7033-4032-9341-7dd3625772bf.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['acanthosis', 'increased glycogen in cells']",
"noisy_text": " So let us discuss about Clear cell acanthoma. Clear cell acanthomas are seen usually in the middle aged and older individuals and the usual site is the lower extremity. Even at this very low power if we see we can see that there is acanthosis that is thickening of this epidermis. So this is the normal skin and this is the normal skin and this is the lesion. So first we have to identify the normal skin. This is normal skin and this is the lesion, normal skin on either sides. And there is a marked acanthosis, a kind of psoriasis form if you will. And here the retrogrids are also quite elongated compared to the normal and they are fused with each other. So the retrogrids at this low power if you look there is a keratosis. In high power we can see that this is parakeratosis. And again these capillaries here are dilated. So we can see in this low power and the most striking feature is there is a kind of pale look to these cells in the epidermis, the skin at no sites. And they are kind of fused with clear, so clear to pale cells. And here there is a sharp demarcation between the abnormal clear to pale cells and the normal cells. So this clear demarcation is a very impressive sign for this entity. Here also we can see this is normal and here there is a clear demarcation. So this pale to clear look is due to increased glycogen in these cells. So these cells have increased glycogen within them. And the second reason is that there",
"corrected_text": " So let us discuss about Clear cell acanthoma. Clear cell acanthomas are seen usually in the middle aged and older individuals and the usual site is the lower extremity. Even at this very low power if we see we can see that there is acanthosis that is thickening of this epidermis. So this is the normal skin and this is the normal skin and this is the lesion. So first we have to identify the normal skin. This is normal skin and this is the lesion, normal skin on either sides. And there is a marked acanthosis, a kind of psoriasis form if you will. And here the rete ridges are also quite elongated compared to the normal and they are fused with each other. So the rete ridges at this low power if you look there is a keratosis. In high power we can see that this is parakeratosis. And again these capillaries here are dilated. So we can see in this low power and the most striking feature is there is a kind of pale look to these cells in the epidermis, the skin at no sites. And they are kind of fused with clear, so clear to pale cells. And here there is a sharp demarcation between the abnormal clear to pale cells and the normal cells. So this clear demarcation is a very impressive sign for this entity. Here also we can see this is normal and here there is a clear demarcation. So this pale to clear look is due to increased glycogen in these cells. So these cells have increased glycogen within them. And the second reason is that there",
"med_umls_ids": "[[{'entity': 'Clear cell acanthomas', 'concept_id': 'C0333992', 'confidence': 1.0}, {'entity': 'middle-aged', 'concept_id': 'C3825963', 'confidence': 0.9554211497306824}, {'entity': 'older', 'concept_id': 'C0337524', 'confidence': 0.7771234512329102}, {'entity': 'individuals', 'concept_id': 'C0027361', 'confidence': 0.8766164779663086}, {'entity': 'lower extremities', 'concept_id': 'C0023216', 'confidence': 0.9999999403953552}], [{'entity': 'acanthosis', 'concept_id': 'C0221270', 'confidence': 1.0}, {'entity': 'elongated', 'concept_id': 'C0205166', 'confidence': 1.0}, {'entity': 'fused', 'concept_id': 'C0699952', 'confidence': 1.0}, {'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}], [{'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'epidermis', 'concept_id': 'C0014520', 'confidence': 1.0}, {'entity': 'pale', 'concept_id': 'C0030232', 'confidence': 1.0}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'increased', 'concept_id': 'C0205217', 'confidence': 1.0}, {'entity': 'glycogen', 'concept_id': 'C0017911', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_145",
"caption_rating": "9"
},
{
"": "1008392",
"caption": "Superficial soft tissue tumors may have a rim of peripheral ossification, which may suggest myositis ossificans based on imaging findings.",
"image_path": "j_rG5XPImFQ_image_7559d4cf-54de-4f3f-8309-769a77ef1c8f.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Hematopathology', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " in the superficial soft tissues, most commonly in the arm, thigh, and calf. They may also have a rim of peripheral ossification, so myocytosis ossificans, which I've talked about in a previous video, may enter the differential based on the imaging findings. These lesions do not have any characteristic molecular alterations. Giant cell tumor of bone usually arises in the epiphyseal region of long bones, but may extend into the adjacent soft tissues. However, this is not a feature of malignancy for these lesions. These tumors also have a characteristic mutation in histone H3.3, with over 90% having the G34W point mutation. And that's all I have for now. If you would like",
"corrected_text": " in the superficial soft tissues, most commonly in the arm, thigh, and calf. They may also have a rim of peripheral ossification, so myositis ossificans, which I've talked about in a previous video, may enter the differential based on the imaging findings. These lesions do not have any characteristic molecular alterations. Giant cell tumor of bone usually arises in the giant cell tumor of bone, but may extend into the adjacent soft tissues. However, this is not a feature of malignancy for these lesions. These tumors also have a characteristic mutation in histone H3.3, with over 90% having the G34W point mutation. And that's all I have for now. If you would like",
"med_umls_ids": "[[{'entity': 'Superficial', 'concept_id': 'C0205124', 'confidence': 1.0}, {'entity': 'soft tissue tumors', 'concept_id': 'C0037579', 'confidence': 1.0}, {'entity': 'rim', 'concept_id': 'C1308727', 'confidence': 1.0}, {'entity': 'peripheral ossification', 'concept_id': 'C0029433', 'confidence': 0.7698169350624084}, {'entity': 'myositis', 'concept_id': 'C0027121', 'confidence': 1.0}, {'entity': 'ossificans', 'concept_id': 'C0029433', 'confidence': 0.7851274013519287}, {'entity': 'imaging', 'concept_id': 'C0011923', 'confidence': 1.0}, {'entity': 'findings', 'concept_id': 'C2607943', 'confidence': 1.0}], [{'entity': 'Giant cell tumor', 'concept_id': 'C0017525', 'confidence': 1.0}, {'entity': 'bone', 'concept_id': 'C0005931', 'confidence': 0.9999999403953552}, {'entity': 'adjacent', 'concept_id': 'C0205117', 'confidence': 1.0}, {'entity': 'soft tissues', 'concept_id': 'C0225317', 'confidence': 1.0}, {'entity': 'malignancy', 'concept_id': 'C0006826', 'confidence': 1.0}, {'entity': 'lesions', 'concept_id': 'C0221198', 'confidence': 1.0}], [{'entity': 'Giant cell tumors', 'concept_id': 'C0017525', 'confidence': 1.0}, {'entity': 'bone', 'concept_id': 'C0005931', 'confidence': 0.9999999403953552}, {'entity': 'bone', 'concept_id': 'C0005931', 'confidence': 0.9999999403953552}, {'entity': 'mutation', 'concept_id': 'C0026882', 'confidence': 1.0}, {'entity': 'histone', 'concept_id': 'C0019652', 'confidence': 1.0}, {'entity': 'H3.3', 'concept_id': 'C0086412', 'confidence': 0.8155916929244995}, {'entity': 'G34W point mutation', 'concept_id': 'C0162735', 'confidence': 0.5941656231880188}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_146",
"caption_rating": "9"
},
{
"": "1007484",
"caption": "Clinical description of a skin condition with small individual papules that have a central crust, often on perioral skin.",
"image_path": "udoW6VSqsm4_image_c9d6bbe3-a848-49a8-acf9-006cbe06a31d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['small individual papules', 'central crust', 'perioral skin', 'granulomatous condition', 'palisade granulostermatitis', 'neutrophilic dermatosis', 'older individuals', 'perineoplastic process']",
"noisy_text": " Yeah, this would be more kind of the classic one, probably. What else? Here's the classic one clinically. What if there's small individual papules that have a central crust in them, often on apral skin? We have had several cases of the disseminated GA, but I'm not sure if they didn't have a crust. So, what's the type that had it? Perforating? Perforating GA. Perforating GA, good. So, this was granulomanuary. There's one other condition that gives you palisade granulostermatitis like this, but it also gives you some neutrophils infiltrate. That palisade and neutrophilic granulostermatitis, that's another thing that you at least have to think about when you see GA. If you see an older person that's got disseminated GA, think about it as a perineoplastic process. Sometimes you",
"corrected_text": " Yeah, this would be more kind of the classic one, probably. What else? Here's the classic one clinically. What if there's small individual papules that have a central crust in them, often on perioral skin? We have had several cases of the disseminated GA, but I'm not sure if they didn't have a crust. So, what's the type that had it? Perforating? Perforating GA. Perforating GA, good. So, this was granulomatous. There's one other condition that gives you palisade granulostermatitis like this, but it also gives you some neutrophils infiltrate. That palisade and neutrophilic dermatosis, that's another thing that you at least have to think about when you see GA. If you see an older person that's got disseminated GA, think about it as a perineoplastic process. Sometimes you",
"med_umls_ids": "[[{'entity': 'Clinical', 'concept_id': 'C0205210', 'confidence': 1.0}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'skin condition', 'concept_id': 'C1719933', 'confidence': 1.0}, {'entity': 'individual', 'concept_id': 'C0027361', 'confidence': 1.0}, {'entity': 'papules', 'concept_id': 'C0332563', 'confidence': 0.9999999403953552}, {'entity': 'central crust', 'concept_id': 'C0205204', 'confidence': 0.7633819580078125}, {'entity': 'perioral skin', 'concept_id': 'C0448802', 'confidence': 0.8075158596038818}], [{'entity': 'Perforating', 'concept_id': 'C0549099', 'confidence': 1.0}, {'entity': 'GA', 'concept_id': 'C0002915', 'confidence': 1.0}, {'entity': 'granulomatous condition', 'concept_id': 'C0439667', 'confidence': 0.8219265341758728}, {'entity': 'palisade', 'concept_id': 'C0331512', 'confidence': 0.8241410255432129}, {'entity': 'granulostermatitis', 'concept_id': 'C0743086', 'confidence': 0.7311265468597412}], [{'entity': 'Neutrophilic dermatosis', 'concept_id': 'C1142272', 'confidence': 1.0}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'GA', 'concept_id': 'C0002915', 'confidence': 1.0}], [{'entity': 'Disseminated', 'concept_id': 'C0205221', 'confidence': 1.0}, {'entity': 'GA', 'concept_id': 'C0002915', 'confidence': 1.0}, {'entity': 'older', 'concept_id': 'C0337524', 'confidence': 0.7771234512329102}, {'entity': 'individuals', 'concept_id': 'C0027361', 'confidence': 0.8766164779663086}, {'entity': 'perineoplastic process', 'concept_id': 'C0027671', 'confidence': 0.8771522045135498}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_147",
"caption_rating": "8"
},
{
"": "1008493",
"caption": "Intraluminal proliferation of epithelium is an important criteria for high-grade dysplasia, which is characterized by loss of cellular polarity, nuclei reaching the surface, prominent nuclei, and cribriform and micropapillary patterns. The concept of dysplasia includes low-grade dysplasia.",
"image_path": "r7OA0Trj5hQ_image_aabd9516-518b-4ec6-b3c7-8960c3f0b8f0.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Nuclei reaching the surface', 'Nuclei reaching the surface']",
"noisy_text": " and connecting the other side of the lumen. So the intra-glandular proliferation of the epithelium is very, very important criteria, which we call it as cribriformic for high-grade dysplasia. So this is a picture of high-grade dysplasia. And the criteria are loss of polarity, nuclei reaching the surface. Here you can see nuclei reaching the surface. Prominent nuclei, if you see carefully for 10 seconds, you can start seeing the nuclei and cribriformic and micropapillary. This concept of dysplasia, low-grade dysplasia and high-grade",
"corrected_text": " and connecting the other side of the lumen. So the intra-glandular proliferation of the epithelium is very, very important criteria, which we call it as cribriform for high-grade dysplasia. So this is a picture of high-grade dysplasia. And the criteria are loss of polarity, nuclei reaching the surface. Here you can see nuclei reaching the surface. Prominent nuclei, if you see carefully for 10 seconds, you can start seeing the nuclei and cribriform and micropapillary. This concept of dysplasia, low-grade dysplasia and high-grade",
"med_umls_ids": "[[{'entity': 'Intraluminal proliferation', 'concept_id': 'C0334094', 'confidence': 0.7116578221321106}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'criteria', 'concept_id': 'C0243161', 'confidence': 0.9999998807907104}, {'entity': 'high-grade dysplasia', 'concept_id': 'C1333110', 'confidence': 0.8831341862678528}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'cellular polarity', 'concept_id': 'C0085304', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'cribriform', 'concept_id': 'C1621425', 'confidence': 0.9999999403953552}, {'entity': 'micropapillary', 'concept_id': 'C1290608', 'confidence': 0.891559898853302}, {'entity': 'concept', 'concept_id': 'C0178566', 'confidence': 1.0}, {'entity': 'dysplasia', 'concept_id': 'C0334044', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'dysplasia', 'concept_id': 'C0334044', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_148",
"caption_rating": "9"
},
{
"": "1005498",
"caption": "Choriocarcinoma of the ovary, also known as non-gestational choriocarcinoma, secretes human chorionic gonadotropin.",
"image_path": "3mRB9j0eyVM_image_492b9987-d0e2-4954-aca0-c9489cd97900.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gynecologic', 'Hematopathology', 'Soft tissue']",
"roi_text": "['Immature teratoma with premature cells invading ovarian stroma', 'Choriocarcinoma of the ovary']",
"noisy_text": " germ cell tumors. You may find malignant teratoma or immature teratoma. Immature teratoma is commonly seen in case of the males. In females the most common teratoma is mature cystic teratoma that is benign tumor. This is immature teratoma, immature teratoma in which you see the premature cells, the neuronal cells and these are invading the stroma, the ovarian stroma. So these contain premature elements. Next is the choriocarcinoma of the ovary that is called non-gestational choriocarcinoma and it secretes human chorionic gonadotropin. It may be",
"corrected_text": " germ cell tumors. You may find malignant teratoma or immature teratoma. Immature teratoma is commonly seen in case of the males. In females the most common teratoma is mature cystic teratoma that is benign tumor. This is immature teratoma, immature teratoma in which you see the premature cells, the neuronal cells and these are invading the stroma, the ovarian stroma. So these contain premature elements. Next is the choriocarcinoma of the ovary that is called non-gestational choriocarcinoma and it secretes human chorionic gonadotropin. It may be",
"med_umls_ids": "[[{'entity': 'germ cell tumors', 'concept_id': 'C0205851', 'confidence': 1.0}, {'entity': 'malignant', 'concept_id': 'C0205282', 'confidence': 1.0}, {'entity': 'immature', 'concept_id': 'C0205252', 'confidence': 1.0}], [{'entity': 'Immature teratoma', 'concept_id': 'C0334520', 'confidence': 1.0}, {'entity': 'males', 'concept_id': 'C0086582', 'confidence': 1.0}, {'entity': 'mature', 'concept_id': 'C0205286', 'confidence': 1.0}, {'entity': 'cystic teratoma', 'concept_id': 'C0011649', 'confidence': 0.9999998807907104}, {'entity': 'benign', 'concept_id': 'C0205183', 'confidence': 1.0}, {'entity': 'females', 'concept_id': 'C0086287', 'confidence': 0.9999999403953552}], [{'entity': 'immature', 'concept_id': 'C0205252', 'confidence': 1.0}, {'entity': 'teratoma', 'concept_id': 'C0039538', 'confidence': 1.0}, {'entity': 'premature cells', 'concept_id': 'C0205252', 'confidence': 0.7552258372306824}, {'entity': 'neuronal cells', 'concept_id': 'C0027882', 'confidence': 0.7867127656936646}, {'entity': 'invade', 'concept_id': 'C1517574', 'confidence': 0.857607364654541}, {'entity': 'ovarian stroma', 'concept_id': 'C0227896', 'confidence': 1.0}], [{'entity': 'Choriocarcinoma', 'concept_id': 'C0008497', 'confidence': 1.0}, {'entity': 'ovary', 'concept_id': 'C0029939', 'confidence': 1.0}, {'entity': 'non-gestational choriocarcinoma', 'concept_id': 'C1135873', 'confidence': 1.0}, {'entity': 'secretes', 'concept_id': 'C1327616', 'confidence': 0.8702053427696228}, {'entity': 'human', 'concept_id': 'C0086418', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "960.0",
"id": "test_149",
"caption_rating": "8"
},
{
"": "1005609",
"caption": "Multinucleated giant cells are foreign body giant cells seen around foreign material that cannot be easily phagocytosed or destroyed.",
"image_path": "rHSTVT91c8Q_image_d219f4dd-4f92-4b07-bb6a-45f0b283bb0b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Cardiac', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Foreign body giant cells seen around some foreign material', 'Brown pigment which is very probably hemosiderin']",
"noisy_text": " multinucleated giant cells are actually transformed macrophages and they are also called foreign body cells or those are those are cells seen around some foreign material that cannot be easily phagocytosed or destroyed and they are transformed macrophages. Here we can see some brown pigment which is very probably hemosiderin and if we want to be sure we can use prussian blue stain or pearls pearls stain and the hemosiderin would turn into blue pigment because of iron ions that mediates this blue reaction. Macrophages that phagocytose the hemosiderin are sometimes called siderophages. Here",
"corrected_text": " multinucleated giant cells are actually transformed macrophages and they are also called foreign body cells or those are those are cells seen around some foreign material that cannot be easily phagocytosed or destroyed and they are transformed macrophages. Here we can see some brown pigment which is very probably hemosiderin and if we want to be sure we can use prussian blue stain or pearls pearls stain and the hemosiderin would turn into blue pigment because of iron ions that mediates this blue reaction. Macrophages that phagocytose the hemosiderin are sometimes called siderophages. Here",
"med_umls_ids": "[[{'entity': 'Multinucleated giant cells', 'concept_id': 'C0017526', 'confidence': 0.9999999403953552}, {'entity': 'foreign body giant cells', 'concept_id': 'C0017527', 'confidence': 1.0}, {'entity': 'foreign material', 'concept_id': 'C0016542', 'confidence': 1.0}, {'entity': 'phagocytosed', 'concept_id': 'C0031308', 'confidence': 0.920818030834198}, {'entity': 'destroyed', 'concept_id': 'C3830528', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_150",
"caption_rating": "8"
},
{
"": "1004900",
"caption": "The presence of numerous melanocytes in the matrix layer is highly suspicious for melanoma in situ.",
"image_path": "8S4LeiO6Bbk_image_0745588b-e17e-42b4-a6c0-d598f293a979.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['nail bed', 'matrix epithelium', 'melanocytes forming nests', 'pagetoid pattern', 'basal layer of the matrix', 'upper portions of the matrix']",
"noisy_text": " we've got nail bed and matricle epithelium. I believe this must be some nail fold, a portion of the nail fold, and then in the bottom piece of tissue in these sections we actually have matricle epithelium and you can see the rete or somewhat hyperplastic. And on higher power examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matricle epithelium in the matricle layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that",
"corrected_text": " we've got nail bed and matrix epithelium. I believe this must be some nail fold, a portion of the nail fold, and then in the bottom piece of tissue in these sections we actually have matrix epithelium and you can see the rete or somewhat hyperplastic. And on higher power examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matrix epithelium in the matrix layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that",
"med_umls_ids": "[[{'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'nail', 'concept_id': 'C0027342', 'confidence': 1.0}, {'entity': 'matrix epithelium', 'concept_id': 'C0014609', 'confidence': 0.7584323883056641}], [{'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'nests', 'concept_id': 'C0035253', 'confidence': 0.7275967001914978}, {'entity': 'upper portions', 'concept_id': 'C0449719', 'confidence': 0.6251541972160339}, {'entity': 'matrix', 'concept_id': 'C0331858', 'confidence': 1.0}, {'entity': 'pagetoid', 'concept_id': 'C1518847', 'confidence': 0.8801172375679016}, {'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}], [{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'matrix layer', 'concept_id': 'C0331858', 'confidence': 0.71736741065979}, {'entity': 'suspicious', 'concept_id': 'C0750493', 'confidence': 1.0}, {'entity': 'melanoma', 'concept_id': 'C0025202', 'confidence': 1.0}, {'entity': 'in situ', 'concept_id': 'C0444498', 'confidence': 0.9999999403953552}]]",
"magnification": "1.0",
"height": "758.0",
"width": "1920.0",
"id": "test_151",
"caption_rating": "9"
},
{
"": "1008391",
"caption": "Giant cell tumor of bone may extend into adjacent soft tissues, but this is not a feature of malignancy for these lesions.",
"image_path": "j_rG5XPImFQ_image_7559d4cf-54de-4f3f-8309-769a77ef1c8f.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Hematopathology', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " in the superficial soft tissues, most commonly in the arm, thigh, and calf. They may also have a rim of peripheral ossification, so myocytosis ossificans, which I've talked about in a previous video, may enter the differential based on the imaging findings. These lesions do not have any characteristic molecular alterations. Giant cell tumor of bone usually arises in the epiphyseal region of long bones, but may extend into the adjacent soft tissues. However, this is not a feature of malignancy for these lesions. These tumors also have a characteristic mutation in histone H3.3, with over 90% having the G34W point mutation. And that's all I have for now. If you would like",
"corrected_text": " in the superficial soft tissues, most commonly in the arm, thigh, and calf. They may also have a rim of peripheral ossification, so myositis ossificans, which I've talked about in a previous video, may enter the differential based on the imaging findings. These lesions do not have any characteristic molecular alterations. Giant cell tumor of bone usually arises in the giant cell tumor of bone, but may extend into the adjacent soft tissues. However, this is not a feature of malignancy for these lesions. These tumors also have a characteristic mutation in histone H3.3, with over 90% having the G34W point mutation. And that's all I have for now. If you would like",
"med_umls_ids": "[[{'entity': 'Superficial', 'concept_id': 'C0205124', 'confidence': 1.0}, {'entity': 'soft tissue tumors', 'concept_id': 'C0037579', 'confidence': 1.0}, {'entity': 'rim', 'concept_id': 'C1308727', 'confidence': 1.0}, {'entity': 'peripheral ossification', 'concept_id': 'C0029433', 'confidence': 0.7698169350624084}, {'entity': 'myositis', 'concept_id': 'C0027121', 'confidence': 1.0}, {'entity': 'ossificans', 'concept_id': 'C0029433', 'confidence': 0.7851274013519287}, {'entity': 'imaging', 'concept_id': 'C0011923', 'confidence': 1.0}, {'entity': 'findings', 'concept_id': 'C2607943', 'confidence': 1.0}], [{'entity': 'Giant cell tumor', 'concept_id': 'C0017525', 'confidence': 1.0}, {'entity': 'bone', 'concept_id': 'C0005931', 'confidence': 0.9999999403953552}, {'entity': 'adjacent', 'concept_id': 'C0205117', 'confidence': 1.0}, {'entity': 'soft tissues', 'concept_id': 'C0225317', 'confidence': 1.0}, {'entity': 'malignancy', 'concept_id': 'C0006826', 'confidence': 1.0}, {'entity': 'lesions', 'concept_id': 'C0221198', 'confidence': 1.0}], [{'entity': 'Giant cell tumors', 'concept_id': 'C0017525', 'confidence': 1.0}, {'entity': 'bone', 'concept_id': 'C0005931', 'confidence': 0.9999999403953552}, {'entity': 'bone', 'concept_id': 'C0005931', 'confidence': 0.9999999403953552}, {'entity': 'mutation', 'concept_id': 'C0026882', 'confidence': 1.0}, {'entity': 'histone', 'concept_id': 'C0019652', 'confidence': 1.0}, {'entity': 'H3.3', 'concept_id': 'C0086412', 'confidence': 0.8155916929244995}, {'entity': 'G34W point mutation', 'concept_id': 'C0162735', 'confidence': 0.5941656231880188}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_152",
"caption_rating": "9"
},
{
"": "1007036",
"caption": "Pigmented histiocytes containing hemocyanin are present in the lesion.",
"image_path": "8S4LeiO6Bbk_image_184b4c7e-959b-4998-8773-3b16a88b79f9.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['lipid vacuoles', 'multinucleated histiocytes', 'ringed siderophages', 'pigmented histiocytes', 'hemocyanin', 'lipid vacuoles', 'multinucleated histiocytes', 'ringed siderophages', 'pigmented histiocytes', 'hemocyanin']",
"noisy_text": " large histiocytes containing lipid. Some of them are multi-nucleated and some of these are actually ringed siderophages. So we see large multi-nucleated histiocytes with a ring of nuclei and they contain not only lipid vacuoles but hemocentaurant. And these are particularly common in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes as suspected is hemocentaurant. If you notice, it's got kind of that golden brown color. If you had a sub-stage condenser or a fine focus knob, you would see that it's somewhat refractile, but unfortunately, we can't use that particular tool when we're looking at scanned images.",
"corrected_text": " large histiocytes containing lipid. Some of them are multinucleated and some of these are actually ringed siderophages. So we see large multinucleated histiocytes with a ring of nuclei and they contain not only lipid vacuoles but hemosiderin. And these are particularly common in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes as suspected is hemosiderin. If you notice, it's got kind of that golden brown color. If you had a sub-stage condenser or a fine focus knob, you would see that it's somewhat refractile, but unfortunately, we can't use that particular tool when we're looking at scanned images.",
"med_umls_ids": "[[{'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'lipid', 'concept_id': 'C0023779', 'confidence': 1.0}, {'entity': 'multinucleated', 'concept_id': 'C0333740', 'confidence': 1.0}, {'entity': 'ringed', 'concept_id': 'C0325501', 'confidence': 0.77345871925354}, {'entity': 'siderophages', 'concept_id': 'C1136253', 'confidence': 0.7251443266868591}], [{'entity': 'Hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}], [{'entity': 'Pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_153",
"caption_rating": "9"
},
{
"": "1008814",
"caption": "The narrator describes a miniaturized hair follicle with a stem cell area known as the mantle zone.",
"image_path": "LlPaENuqzVQ_image_0b19780d-498f-43a1-90f3-f4bfc4ead6d3.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['miniaturized hair follicle', 'mantle zone', 'stem cell area', 'bulge', 'apocrine gland', 'sebaceous gland', 'hamartoma', 'fibrous sheath', 'miniaturized hair follicle', 'mantle zone', 'stem cell area', 'bulge', 'apocrine gland', 'sebaceous gland', 'hamartoma', 'fibrous sheath']",
"noisy_text": " Like, it looks more like if there's, if I'm going to guess, like there's, I feel like there's a little bit of like, I would guess more like towards the, like a glandular. Yeah, well, it's, it's, it's a little miniaturized hair follicle. Nope. It's like this little guy here. It's like a little tiny follicle. And there's, we always think of three parts of the hair follicle. We think of the infundibulum, the isthmus, and we think of the inferior portion, but there's a very important part right around the isthmic part, just beneath the follicle, the infundibulum, and then where the inferior portion begins, that's known as the mantle zone. And that's kind of where all the action is. That's really kind of a stem cell area that sometimes those cells will form a little bulge there and they actually will end up forming an apocrine gland. Sometimes they'll end up forming a sebaceous gland. Sometimes they, you know, will just, they'll form, sometimes they form a little hammertoma, like you see right here. And they actually end up getting you this little sort of primitive little, it almost looks like a mini hair follicle that didn't really form. And then when you look at a hair follicle, it's comprised not only of the epithelial component, but there's also a periepithelial sheath around it, a fibrous sheath around the hair follicle. And so this is a hammertoma that involves both of those. So it's got a fibrous element to it. And then",
"corrected_text": " Like, it looks more like if there's, if I'm going to guess, like there's, I feel like there's a little bit of like, I would guess more like towards the, like a glandular. Yeah, well, it's, it's, it's a little miniaturized hair follicle. Nope. It's like this little guy here. It's like a little tiny follicle. And there's, we always think of three parts of the hair follicle. We think of the infundibulum, the isthmus, and we think of the inferior portion, but there's a very important part right around the isthmic part, just beneath the follicle, the infundibulum, and then where the inferior portion begins, that's known as the mantle zone. And that's kind of where all the action is. That's really kind of a stem cell area that sometimes those cells wiform a little bulge there and they actually wiend up forming an apocrine gland. Sometimes they'end up forming a sebaceous gland. Sometimes they, you know, will just, they'form, sometimes they form a little hamartoma, like you see right here. And they actually end up getting you this little sort of primitive little, it almost looks like a mini hair follicle that didn't really form. And then when you look at a hair follicle, it's comprised not only of the epithelial component, but there's also a periepithelial sheath around it, a fibrous sheath around the hair follicle. And so this is a hamartoma that involves both of those. So it's got a fibrous element to it. And then",
"med_umls_ids": "[[{'entity': 'narrator', 'concept_id': 'C1135957', 'confidence': 0.7711340188980103}, {'entity': 'miniaturized', 'concept_id': 'C0872350', 'confidence': 0.8111259341239929}, {'entity': 'hair follicle', 'concept_id': 'C0221971', 'confidence': 1.0}, {'entity': 'stem cell', 'concept_id': 'C0038250', 'confidence': 1.0}, {'entity': 'mantle zone', 'concept_id': 'C1512987', 'confidence': 1.0}], [{'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'mantle', 'concept_id': 'C0232445', 'confidence': 0.8497024178504944}, {'entity': 'zone', 'concept_id': 'C1710706', 'confidence': 1.0}, {'entity': 'bulge', 'concept_id': 'C0038999', 'confidence': 0.9999999403953552}, {'entity': 'apocrine gland', 'concept_id': 'C0003584', 'confidence': 0.9999998807907104}, {'entity': 'sebaceous gland', 'concept_id': 'C0036505', 'confidence': 1.0}, {'entity': 'hamartoma', 'concept_id': 'C0018552', 'confidence': 0.9999999403953552}], [{'entity': 'hamartoma', 'concept_id': 'C0018552', 'confidence': 0.9999999403953552}, {'entity': 'epithelial component', 'concept_id': 'C1707933', 'confidence': 0.8783122897148132}, {'entity': 'fibrous sheath', 'concept_id': 'C1185724', 'confidence': 1.0}, {'entity': 'hair follicle', 'concept_id': 'C0221971', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_154",
"caption_rating": "7"
},
{
"": "1005854",
"caption": "The band of inflammatory cells and capillaries is thick and irregular, with feet-like projections into the lamina propria.",
"image_path": "sDFjOtMAYrk_image_5e221488-360a-4909-aa07-cffbf8844034.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['gland dropout', 'lamina propria', 'inflammatory cells', 'plasma cells', 'lymphocytes', 'eosinophils', 'capillaries', 'epithelium', 'gland dropout', 'lamina propria', 'inflammatory cells', 'plasma cells', 'lymphocytes', 'eosinophils', 'capillaries', 'epithelium']",
"noisy_text": " you know, gland dropout here and there, but that's okay. What else? Yeah. So expansion of the lamina appropriate by inflammatory cells that includes plasma cells, lymphocytes, and some eos. And what else? Yeah, exactly. So the band interrupts inflammatory cells and capillaries, and it's not just the thickness of the band that really catches your eyes, the irregularity of it. So you don't have a thin smooth line anymore. It's just, you know, thick and irregular, just just throwing like feet down into the, into the lamina appropriate. There are also a few lymphocytes in the epithelium, but that's not the main finding. The other thing you might find",
"corrected_text": " you know, gland dropout here and there, but that's okay. What else? Yeah. So expansion of the lamina appropriate by inflammatory cells that includes plasma cells, lymphocytes, and some eos. And what else? Yeah, exactly. So the band interrupts inflammatory cells and capillaries, and it's not just the thickness of the band that really catches your eyes, the irregularity of it. So you don't have a thin smooth line anymore. It's just, you know, thick and irregular, just just throwing like feet down into the, into the lamina appropriate. There are also a few lymphocytes in the epithelium, but that's not the main finding. The other thing you might find",
"med_umls_ids": "[[{'entity': 'Inflammatory cells', 'concept_id': 'C0440752', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'expansion', 'concept_id': 'C0007595', 'confidence': 0.8664658665657043}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}], [{'entity': 'band', 'concept_id': 'C0175723', 'confidence': 1.0}, {'entity': 'inflammatory cells', 'concept_id': 'C0440752', 'confidence': 1.0}, {'entity': 'capillaries', 'concept_id': 'C0006901', 'confidence': 0.9999998807907104}, {'entity': 'irregular', 'concept_id': 'C0205271', 'confidence': 1.0}, {'entity': 'projections', 'concept_id': 'C0016538', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}], [{'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_155",
"caption_rating": "9"
},
{
"": "1008954",
"caption": "EMA, Clodin-1, and Glut-1 are immunohistochemical stains that can help diagnose perineuriomas, but low-grade fibrosarcomas can also express EMA and Clodin-1.",
"image_path": "QDb68_G1HR4_image_aeb1e9b8-0fa5-431a-89b7-ff906dab1235.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Deep soft tissue', 'Perineurioma', 'Low-grade fibromyxoid sarcoma', 'Immunohistochemistry', 'Swirling growth']",
"noisy_text": " involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is more of a difficult problem because perineurioma has a lot of overlap histologically with low-grade fibromyxoid sarcoma and also immunohistochemically. On immunostains, EMA, Clodin-1 and Glut-1 are three immunostains that will usually stain perineuriomas. The problem is that low-grade fibromyxoid sarcomas often express at least focal EMA, so that's a problem and additionally, the examples of low-grade fibromyxoid sarcoma that have dramatic swirling and whirling growth, those are the ones that have a perineurioma like pattern, the ones that mimic perineurioma. They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The",
"corrected_text": " involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is more of a difficult problem because perineurioma has a lot of overlap histologically with low-grade fibromyxoid sarcoma and also immunohistochemically. On immunostains, EMA, Clodin-1 and Glut-1 are three immunostains that will usually stain perineuriomas. The problem is that low-grade fibromyxoid sarcomas often express at least focal EMA, so that's a problem and additionally, the examples of low-grade fibromyxoid sarcoma that have dramatic swirling and whirling growth, those are the ones that have a perineurioma like pattern, the ones that mimic perineurioma. They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The",
"med_umls_ids": "[[{'entity': 'CD34', 'concept_id': 'C0054953', 'confidence': 1.0}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'deep soft tissue tumors', 'concept_id': 'C0037579', 'confidence': 0.8622524738311768}], [{'entity': 'Perineurioma', 'concept_id': 'C0751691', 'confidence': 0.9999999403953552}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'histologically', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'immunohistochemistry', 'concept_id': 'C0021044', 'confidence': 0.9999998807907104}], [{'entity': 'EMA', 'concept_id': 'C0268596', 'confidence': 0.9999999403953552}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}, {'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'immunohistochemical stains', 'concept_id': 'C4317108', 'confidence': 0.9999999403953552}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibrosarcomas', 'concept_id': 'C0016057', 'confidence': 1.0}, {'entity': 'EMA', 'concept_id': 'C0268596', 'confidence': 0.9999999403953552}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}], [{'entity': 'Low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'swirling', 'concept_id': 'C0233591', 'confidence': 0.7064549922943115}, {'entity': 'growth', 'concept_id': 'C0018270', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'express', 'concept_id': 'C0017262', 'confidence': 0.8176293969154358}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}], [{'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'reports', 'concept_id': 'C0684224', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcomas', 'concept_id': 'C1275282', 'confidence': 0.8123146891593933}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_156",
"caption_rating": "8"
},
{
"": "1004877",
"caption": "Bladder neck tissue can be present in a TUR-BT sample and prostate tissue can be present in a TUR-P sample.",
"image_path": "iklRyY1nBIE_image_f478f409-67bd-40fc-b80f-d5ca0105e9d1.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['High-grade prostatic adenocarcinoma intimately associated with small cell carcinoma.']",
"noisy_text": " sometimes you get bladder neck tissue in the same sample. And when we have a discussion tomorrow about the bladder cases, the same thing happens in the bladder. You can get a so-called TUR-BT sample that has prostate tissue present. In the prostate, you can have a TUR-P sample that has bladder neck tissue present. And in this particular case, as I said, we were fortunate enough to have high-grade conventional prostate cancer intimately associated with this small cell carcinoma. So it's most likely the differentiation of that. But there are some cases in which there is no well-differentiated or conventional cancer anywhere. All you see is small cell. And then the clinicians may ask, where is this coming from? Is this coming from the prostate? Is this coming from the bladder? And sometimes it's a challenge. Some of us would say it's probably an academic question because they're going to be treated the same way. But sometimes our clinical colleagues want to know. Because things like androgen deprivation therapy are off the table if it's coming from the prostate. And there are different ways one can figure that out. If you're fortunate enough to have egg expression, because studies have shown this, if you're fortunate enough",
"corrected_text": " sometimes you get bladder neck tissue in the same sample. And when we have a discussion tomorrow about the bladder cases, the same thing happens in the bladder. You can get a so-called TUR-BT sample that has prostate tissue present. In the prostate, you can have a TUR-P sample that has bladder neck tissue present. And in this particular case, as I said, we were fortunate enough to have high-grade conventional prostate cancer intimately associated with this small cell carcinoma. So it's most likely the differentiation of that. But there are some cases in which there is no well-differentiated or conventional cancer anywhere. All you see is small cell. And then the clinicians may ask, where is this coming from? Is this coming from the prostate? Is this coming from the bladder? And sometimes it's a challenge. Some of us would say it's probably an academic question because they're going to be treated the same way. But sometimes our clinical colleagues want to know. Because things like androgen deprivation therapy are off the table if it's coming from the prostate. And there are different ways one can figure that out. If you're fortunate enough to have egg expression, because studies have shown this, if you're fortunate enough",
"med_umls_ids": "[[{'entity': 'Bladder', 'concept_id': 'C0005682', 'confidence': 1.0}, {'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'prostate tissue', 'concept_id': 'C1514521', 'confidence': 0.8824390769004822}, {'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}], [{'entity': 'High-grade prostatic adenocarcinoma', 'concept_id': 'C3642254', 'confidence': 0.7883367538452148}, {'entity': 'associated with', 'concept_id': 'C0332281', 'confidence': 1.0}, {'entity': 'small cell carcinoma', 'concept_id': 'C0149925', 'confidence': 1.0}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}], [{'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'conventional', 'concept_id': 'C0439858', 'confidence': 1.0}, {'entity': 'cancer', 'concept_id': 'C0006826', 'confidence': 0.9999998807907104}, {'entity': 'present', 'concept_id': 'C0150312', 'confidence': 0.9999998807907104}, {'entity': 'small cell carcinoma', 'concept_id': 'C0149925', 'confidence': 1.0}], [{'entity': 'Differentiating', 'concept_id': 'C0205615', 'confidence': 1.0}, {'entity': 'origin', 'concept_id': 'C0079946', 'confidence': 1.0}, {'entity': 'small cell carcinoma', 'concept_id': 'C0149925', 'confidence': 1.0}, {'entity': 'treatment', 'concept_id': 'C0039798', 'confidence': 1.0}, {'entity': 'decisions', 'concept_id': 'C0679006', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_157",
"caption_rating": "8"
},
{
"": "1005995",
"caption": "Relatively normal bone marrow with trilinear hematopoiesis and normal cellularity.",
"image_path": "jF_pj4-tEC8_image_e2584fb4-94f6-433a-989a-48f60a75a639.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Pulmonary', 'Cardiac', 'Gastrointestinal']",
"roi_text": "['Increase in eosinophils']",
"noisy_text": " even with the normal marrow, you have some increase in eosinophils, but we know in perspective with this person having asthma, some of that eosinophilia is coming from this person's history of asthma, but there's quite a bit of eosinophils there, but the ME ratio was adequate, maybe four to one in evidence of trilinear hematopoiesis, and so this was a relatively 80% bone marrow with normal cellularity and trilinear hematopoiesis, so very normal looking bone marrow, and I do that, I have a few plasma cells in here as well, but they're not to",
"corrected_text": " even with the normal marrow, you have some increase in eosinophils, but we know in perspective with this person having asthma, some of that eosinophilia is coming from this person's history of asthma, but there's quite a bit of eosinophils there, but the ME ratio was adequate, maybe four to one in evidence of trilinear hematopoiesis, and so this was a relatively 80% bone marrow with normal cellularity and trilinear hematopoiesis, so very normal looking bone marrow, and I do that, I have a few plasma cells in here as well, but they're not to",
"med_umls_ids": "[[{'entity': 'Increase', 'concept_id': 'C0442805', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'normal marrow', 'concept_id': 'C1292131', 'confidence': 0.8076969981193542}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'patient\u2019s history of asthma', 'concept_id': 'C0455544', 'confidence': 0.8792974948883057}], [{'entity': 'bone marrow', 'concept_id': 'C0005953', 'confidence': 1.0}, {'entity': 'trilinear hematopoiesis', 'concept_id': 'C0018951', 'confidence': 0.7991899251937866}, {'entity': 'normal cellularity', 'concept_id': 'C0178539', 'confidence': 0.8253751993179321}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "608.0",
"id": "test_158",
"caption_rating": "9"
},
{
"": "1005556",
"caption": "Presence of nuclear and cytoplasmic inclusion indicating CMV infection which affects mesenchymal derived cells first, endothelial cells and fibroblasts leading to vasculitis and ischemia.",
"image_path": "r7OA0Trj5hQ_image_35ef396e-6c1e-419c-aa25-1ce82bbc4f71.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['endothelial cells', 'vasculitis and ischemia']",
"noisy_text": " nuclear and cytoplasmic inclusion. These are CMV infection. These are all involving blood vessels. One thing for CMV, it affects mesenchymal derived cells first, endothelial cells and the fibroblasts. Since it's involving the endothelial cells, it produces vasculitis and ischemia. And that's why most of the CMV gastroenteropathy is associated with ischemic changes because of the overlapping vasculitis. Here, it is involving more epithelium. Whereas here, it's involving more endothelium. This is a special strain, gastric biopsy again. You see",
"corrected_text": " nuclear and cytoplasmic inclusion. These are CMV infection. These are all involving blood vessels. One thing for CMV, it affects mesenchymal derived cells first, endothelial cells and the fibroblasts. Since it's involving the endothelial cells, it produces vasculitis and ischemia. And that's why most of the CMV gastroenteropathy is associated with ischemic changes because of the overlapping vasculitis. Here, it is involving more epithelium. Whereas here, it's involving more endothelium. This is a special strain, gastric biopsy again. You see",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'nuclear', 'concept_id': 'C0521447', 'confidence': 1.0}, {'entity': 'cytoplasmic', 'concept_id': 'C0010834', 'confidence': 1.0}, {'entity': 'inclusion', 'concept_id': 'C0007637', 'confidence': 1.0}, {'entity': 'CMV infection', 'concept_id': 'C0010823', 'confidence': 1.0}, {'entity': 'mesenchymal', 'concept_id': 'C1513143', 'confidence': 1.0}, {'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'endothelial cells', 'concept_id': 'C0225336', 'confidence': 1.0}, {'entity': 'fibroblasts', 'concept_id': 'C0016030', 'confidence': 1.0}, {'entity': 'vasculitis', 'concept_id': 'C0042384', 'confidence': 1.0}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_159",
"caption_rating": "9"
},
{
"": "1008444",
"caption": "CD34 can help diagnose deep soft tissue tumors.",
"image_path": "QDb68_G1HR4_image_8772a4d0-5e6a-4322-9ff2-d521cda51a2d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Deep soft tissue', 'Perineurioma', 'Low-grade fibromyxoid sarcoma', 'Immunohistochemistry', 'Swirling growth', 'Deep soft tissue', 'Perineurioma', 'Low-grade fibromyxoid sarcoma', 'Immunohistochemistry', 'Swirling growth']",
"noisy_text": " involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is more of a difficult problem because perineurioma has a lot of overlap histologically with low-grade fibromyxoid sarcoma and also immunohistochemically. On immunostains, EMA, Clodin-1 and Glut-1 are three immunostains that will usually stain perineuriomas. The problem is that low-grade fibromyxoid sarcomas often express at least focal EMA, so that's a problem and additionally, the examples of low-grade fibromyxoid sarcoma that have dramatic swirling and whirling growth, those are the ones that have a perineurioma like pattern, the ones that mimic perineurioma. They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The",
"corrected_text": " involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is more of a difficult problem because perineurioma has a lot of overlap histologically with low-grade fibromyxoid sarcoma and also immunohistochemically. On immunostains, EMA, Clodin-1 and Glut-1 are three immunostains that will usually stain perineuriomas. The problem is that low-grade fibromyxoid sarcomas often express at least focal EMA, so that's a problem and additionally, the examples of low-grade fibromyxoid sarcoma that have dramatic swirling and whirling growth, those are the ones that have a perineurioma like pattern, the ones that mimic perineurioma. They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The",
"med_umls_ids": "[[{'entity': 'CD34', 'concept_id': 'C0054953', 'confidence': 1.0}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'deep soft tissue tumors', 'concept_id': 'C0037579', 'confidence': 0.8622524738311768}], [{'entity': 'Perineurioma', 'concept_id': 'C0751691', 'confidence': 0.9999999403953552}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'histologically', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'immunohistochemistry', 'concept_id': 'C0021044', 'confidence': 0.9999998807907104}], [{'entity': 'EMA', 'concept_id': 'C0268596', 'confidence': 0.9999999403953552}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}, {'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'immunohistochemical stains', 'concept_id': 'C4317108', 'confidence': 0.9999999403953552}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibrosarcomas', 'concept_id': 'C0016057', 'confidence': 1.0}, {'entity': 'EMA', 'concept_id': 'C0268596', 'confidence': 0.9999999403953552}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}], [{'entity': 'Low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'swirling', 'concept_id': 'C0233591', 'confidence': 0.7064549922943115}, {'entity': 'growth', 'concept_id': 'C0018270', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'express', 'concept_id': 'C0017262', 'confidence': 0.8176293969154358}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}], [{'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'reports', 'concept_id': 'C0684224', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcomas', 'concept_id': 'C1275282', 'confidence': 0.8123146891593933}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_160",
"caption_rating": "7"
},
{
"": "1006050",
"caption": "Slightly hyperplastic epidermis and a cellular infiltrate throughout the dermis.",
"image_path": "8S4LeiO6Bbk_image_02e79690-5b3a-4acd-b1f7-045efdd9787d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['infiltrate filling the dermis and extending into the subcutaneous tissue', 'brown pigment near the surface', 'hyperplastic epidermis', 'cellular infiltrate throughout the dermis', 'infiltrate filling the dermis and extending into the subcutaneous tissue', 'brown pigment near the surface', 'hyperplastic epidermis', 'cellular infiltrate throughout the dermis']",
"noisy_text": " a large punch biopsy. And I think this actually was two punch biopsies from one lesion, each one bisected. And we can see that we've got an infiltrate filling the dermis and extending into the subcutaneous tissue. The infiltrate appears to be compressing the fat rather than growing in between the adipocytes. And I think it's scanning magnification, you know, one of the things that you can really begin to appreciate, not only the fact that this lesion is partially sampled, that it extends to the base and edges of the specimen, but one can begin to appreciate abundant hemorrhage within this tumor. And in addition, we can see some brown pigment near the surface. And common sense will tell you where there's smoke, there's fire. Since we do have all this abundant hemorrhage, there's a high probability that the pigment, this brownish gold pigment that we're seeing up near the surface of the specimen is likely hemocentaurant rather than melanin. But we'll confirm that when we go down to a higher power. As we move in, we can see that the epidermis is slightly hyperplastic. We've got this cellular infiltrate throughout the dermis and we'll need to go down and take a look at this infiltrate. It appears a little less dense at the",
"corrected_text": " a large punch biopsy. And I think this actually was two punch biopsies from one lesion, each one bisected. And we can see that we've got an infiltrate filling the dermis and extending into the subcutaneous tissue. The infiltrate appears to be compressing the fat rather than growing in between the adipocytes. And I think it's scanning magnification, you know, one of the things that you can really begin to appreciate, not only the fact that this lesion is partially sampled, that it extends to the base and edges of the specimen, but one can begin to appreciate abundant hemorrhage within this tumor. And in addition, we can see some brown pigment near the surface. And common sense will tell you where there's smoke, there's fire. Since we do have all this abundant hemorrhage, there's a high probability that the pigment, this brownish gold pigment that we're seeing up near the surface of the specimen is likely hemocentaurant rather than melanin. But we'confirm that when we go down to a higher power. As we move in, we can see that the epidermis is slightly hyperplastic. We've got this cellular infiltrate throughout the dermis and we'll need to go down and take a look at this infiltrate. It appears a little less dense at the",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'punch biopsy', 'concept_id': 'C0182557', 'confidence': 1.0}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'filling', 'concept_id': 'C0178866', 'confidence': 0.7777882218360901}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'subcutaneous tissue', 'concept_id': 'C0222331', 'confidence': 1.0}], [{'entity': 'Excessive', 'concept_id': 'C0442802', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'brown pigment near', 'concept_id': 'C4555503', 'confidence': 0.865685760974884}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}], [{'entity': 'hyperplastic epidermis', 'concept_id': 'C4748317', 'confidence': 0.7633129358291626}, {'entity': 'cellular infiltrate', 'concept_id': 'C1692321', 'confidence': 1.0}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_161",
"caption_rating": "9"
},
{
"": "1006973",
"caption": "The architecture of the glands is distorted and abnormal, indicating chronicity. No specific features are present in chronic inflammatory colonic pathology.",
"image_path": "sDFjOtMAYrk_image_822a110c-72bb-4114-b0ac-78a3f657409d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['Distorted architecture of the glands.', 'Distorted architecture of the glands.']",
"noisy_text": " architecture. The glands start to look like anything they want to look like. Rabbits, monkeys, the face of Jesus, whatever, except for test tubes on a rack. And the other thing is, sometimes you'll see them instead of growing down, they'll grow sideways. So, that's very apparent, very abnormal. So, I would say this is great evidence of chronicity, good architectural distortion. What other features besides architecture can you see in cases where there's some chronicity, albeit nonspecific findings? I mean, nothing is specific in chronic inflammatory colonic pathology, but what other features would you expect to see in patients with inflammatory bowel disease? I don't remember, I think this is obviously from the right colon. So, if we see it here, it doesn't matter. But in cases from the left colon, what's a good finding that indicates chronicity? Yes,",
"corrected_text": " architecture. The glands start to look like anything they want to look like. Rabbits, monkeys, the face of Jesus, whatever, except for test tubes on a rack. And the other thing is, sometimes you'll see them instead of growing down, they'll grow sideways. So, that's very apparent, very abnormal. So, I would say this is great evidence of chronicity, good architectural distortion. What other features besides architecture can you see in cases where there's some chronicity, albeit nonspecific findings? I mean, nothing is specific in chronic inflammatory colonic pathology, but what other features would you expect to see in patients with inflammatory bowel disease? I don't remember, I think this is obviously from the right colon. So, if we see it here, it doesn't matter. But in cases from the left colon, what's a good finding that indicates chronicity? Yes,",
"med_umls_ids": "[[{'entity': 'architecture', 'concept_id': 'C0003737', 'confidence': 1.0}, {'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'distorted', 'concept_id': 'C0700135', 'confidence': 1.0}, {'entity': 'abnormal', 'concept_id': 'C0205161', 'confidence': 1.0}, {'entity': 'chronicity', 'concept_id': 'C0547045', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'chronic inflammatory colonic', 'concept_id': 'C0021376', 'confidence': 0.8024523258209229}, {'entity': 'pathology', 'concept_id': 'C0030664', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_162",
"caption_rating": "8"
},
{
"": "1007442",
"caption": "Comparison of granulomas in sarcoidosis and Crohn\u2019s disease.",
"image_path": "sDFjOtMAYrk_image_64ecfd50-c3b0-487d-b33a-10de6f769850.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['uveitis with characteristic features', 'granulomas in sarcoidosis and Crohn\u2019s disease', 'uveitis with characteristic features', 'granulomas in sarcoidosis and Crohn\u2019s disease']",
"noisy_text": " patient had sarcoid. So I said, this is probably not IBD, clinicians came down, we want to look at the biopsy, of course. It turns out that they went back and talked to the patient. The patient has a history of uveitis with characteristic features that were good for sarcoidosis. Nobody knew about they treated the patient for sarcoid, re-biopsied the patient. And he was fine. There were no more granulomas on multiple repeat biopsies. And now compare those grannies with the grannies in Crohn's. So here's a giant cell right there, but there was a better one right there. So they're like kind of",
"corrected_text": " patient had sarcoid. So I said, this is probably not IBD, clinicians came down, we want to look at the biopsy, of course. It turns out that they went back and talked to the patient. The patient has a history of uveitis with characteristic features that were good for sarcoidosis. Nobody knew about they treated the patient for sarcoid, re-biopsied the patient. And he was fine. There were no more granulomas on multiple repeat biopsies. And now compare those grannies with the grannies in Crohn's. So here's a giant cell right there, but there was a better one right there. So they're like kind of",
"med_umls_ids": "[[{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'suspected', 'concept_id': 'C0332147', 'confidence': 1.0}, {'entity': 'IBD', 'concept_id': 'C0021390', 'confidence': 1.0}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'history', 'concept_id': 'C0019664', 'confidence': 1.0}, {'entity': 'uveitis', 'concept_id': 'C0042164', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'treated', 'concept_id': 'C1522326', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'biopsies', 'concept_id': 'C0005558', 'confidence': 1.0}, {'entity': 'granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}], [{'entity': 'Comparison', 'concept_id': 'C1707455', 'confidence': 1.0}, {'entity': 'granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'Crohn\u2019s disease', 'concept_id': 'C0010346', 'confidence': 0.8916962146759033}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_163",
"caption_rating": "7"
},
{
"": "1004606",
"caption": "There are not many viable adipocytes left in the subcutaneous tissue.",
"image_path": "hoV-JkD6Wb0_image_a9954815-75a0-4513-ac9c-cf559c4e861d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['Lesion with induration and yellow periphery', 'Nodular angioplasia in the papillary dermis', 'Septal and lobular panniculitis', 'Distortion of fat architecture', 'Stasis-related vascular change', 'Subcutaneous tissue with few viable adipocytes', 'Lesion with induration and yellow periphery', 'Nodular angioplasia in the papillary dermis', 'Septal and lobular panniculitis', 'Distortion of fat architecture', 'Stasis-related vascular change', 'Subcutaneous tissue with few viable adipocytes']",
"noisy_text": " injurated, looks a little yellow over at the periphery, a little red center light, and a large punch biopsy through this lesion reveals evidence within the papillary dermis of nodular angioplasia, so we have a little bit of stasis-related vascular change, but not much inflammation. In this particular instance, we have a rip-roaring paniculitis here. We have a lobular paniculitis. If you take a look at the fat here, there's total distortion of the architecture, and this is barely discernible as subcutaneous tissue, but there's not a lot of inflammation. There aren't many viable adipocytes left here. A lot of the adipocytes have kind of ruptured and fused,",
"corrected_text": " indurated, looks a little yellow over at the periphery, a little red center light, and a large punch biopsy through this lesion reveals evidence within the papillary dermis of nodular angioplasia, so we have a little bit of stasis-related vascular change, but not much inflammation. In this particular instance, we have a lobular panniculitis here. We have a lobular panniculitis. If you take a look at the fat here, there's total distortion of the architecture, and this is barely discernible as subcutaneous tissue, but there's not a lot of inflammation. There aren't many viable adipocytes left here. A lot of the adipocytes have kind of ruptured and fused,",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'indurated', 'concept_id': 'C0702114', 'confidence': 1.0}, {'entity': 'yellow periphery', 'concept_id': 'C0221205', 'confidence': 0.7174375653266907}, {'entity': 'red center light', 'concept_id': 'C0563227', 'confidence': 0.7959515452384949}], [{'entity': 'Punch biopsy', 'concept_id': 'C0182557', 'confidence': 1.0}, {'entity': 'nodular angioplasia', 'concept_id': 'C0205297', 'confidence': 0.6163609623908997}, {'entity': 'papillary dermis', 'concept_id': 'C0682598', 'confidence': 1.0}], [{'entity': 'Septal', 'concept_id': 'C0442004', 'confidence': 0.9999999403953552}, {'entity': 'lobular panniculitis', 'concept_id': 'C0263012', 'confidence': 1.0}, {'entity': 'distortion', 'concept_id': 'C0332482', 'confidence': 1.0}, {'entity': 'fat architecture', 'concept_id': 'C0003737', 'confidence': 0.88345867395401}], [{'entity': 'stasis-related vascular change', 'concept_id': 'C0005847', 'confidence': 0.522698700428009}, {'entity': 'inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}], [{'entity': 'adipocytes', 'concept_id': 'C0206131', 'confidence': 1.0}, {'entity': 'left', 'concept_id': 'C0205091', 'confidence': 1.0}, {'entity': 'subcutaneous tissue', 'concept_id': 'C0222331', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_164",
"caption_rating": "7"
},
{
"": "1007914",
"caption": "There are several melanocytes present, some forming nests and extending into the upper portions of the matrix in a pagetoid pattern.",
"image_path": "8S4LeiO6Bbk_image_d5b1b003-cbe4-408e-815b-f0a4aa81b2b9.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['nail bed', 'matrix epithelium', 'melanocytes forming nests', 'pagetoid pattern', 'basal layer of the matrix', 'upper portions of the matrix', 'nail bed', 'matrix epithelium', 'melanocytes forming nests', 'pagetoid pattern', 'basal layer of the matrix', 'upper portions of the matrix']",
"noisy_text": " we've got nail bed and matricle epithelium. I believe this must be some nail fold, a portion of the nail fold, and then in the bottom piece of tissue in these sections we actually have matricle epithelium and you can see the rete or somewhat hyperplastic. And on higher power examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matricle epithelium in the matricle layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that",
"corrected_text": " we've got nail bed and matrix epithelium. I believe this must be some nail fold, a portion of the nail fold, and then in the bottom piece of tissue in these sections we actually have matrix epithelium and you can see the rete or somewhat hyperplastic. And on higher power examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matrix epithelium in the matrix layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that",
"med_umls_ids": "[[{'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'nail', 'concept_id': 'C0027342', 'confidence': 1.0}, {'entity': 'matrix epithelium', 'concept_id': 'C0014609', 'confidence': 0.7584323883056641}], [{'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'nests', 'concept_id': 'C0035253', 'confidence': 0.7275967001914978}, {'entity': 'upper portions', 'concept_id': 'C0449719', 'confidence': 0.6251541972160339}, {'entity': 'matrix', 'concept_id': 'C0331858', 'confidence': 1.0}, {'entity': 'pagetoid', 'concept_id': 'C1518847', 'confidence': 0.8801172375679016}, {'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}], [{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'matrix layer', 'concept_id': 'C0331858', 'confidence': 0.71736741065979}, {'entity': 'suspicious', 'concept_id': 'C0750493', 'confidence': 1.0}, {'entity': 'melanoma', 'concept_id': 'C0025202', 'confidence': 1.0}, {'entity': 'in situ', 'concept_id': 'C0444498', 'confidence': 0.9999999403953552}]]",
"magnification": "1.0",
"height": "758.0",
"width": "1920.0",
"id": "test_165",
"caption_rating": "9"
},
{
"": "1004312",
"caption": "MUC4 stain is used to confirm the diagnosis of cellular intramuscular myxoma.",
"image_path": "QDb68_G1HR4_image_72696061-bdf2-437c-a2ee-0049bbeeccaa.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['myxoid features', 'fine delicate collagen', 'cellular intramuscular myxoma', 'fibrous areas', 'cellular areas', 'MUC4 stain']",
"noisy_text": " Here's again the myxoid background I really think this is very helpful. The very very fine delicate collagen that you see. Now areas like this I think can kind of resemble what you see in a so-called cellular intramuscular myxoma. Intramuscular myxomas are usually very blue and myxoid very hypocellular but sometimes they get more fibrous and more cellular areas. And on a needle biopsy I think that can be challenging. So I think usually with some experience you can tell them apart on H and E most of the time but when I have any doubt I just do a MUC4 stain. The MUC4 is negative and on a needle it looks like a myxoma with some kind of fibrous or a little bit more cellular areas and then I just say that it's probably a cellular intramuscular myxoma. So I think MUC4",
"corrected_text": " Here's again the myxoid background I really think this is very helpful. The very very fine delicate collagen that you see. Now areas like this I think can kind of resemble what you see in a so-called cellular intramuscular myxoma. Intramuscular myxomas are usually very blue and myxoid very hypocellular but sometimes they get more fibrous and more cellular areas. And on a needle biopsy I think that can be challenging. So I think usually with some experience you can tell them apart on H and E most of the time but when I have any doubt I just do a MUC4 stain. The MUC4 is negative and on a needle it looks like a myxoma with some kind of fibrous or a little bit more cellular areas and then I just say that it's probably a cellular intramuscular myxoma. So I think MUC4",
"med_umls_ids": "[[{'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'myxoid', 'concept_id': 'C0205295', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}], [{'entity': 'narrator', 'concept_id': 'C1135957', 'confidence': 0.7711340188980103}, {'entity': 'cellular', 'concept_id': 'C0007634', 'confidence': 0.9999999403953552}, {'entity': 'intramuscular', 'concept_id': 'C0442117', 'confidence': 1.0}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}, {'entity': 'cellular areas', 'concept_id': 'C0007634', 'confidence': 0.7882957458496094}], [{'entity': 'MUC4', 'concept_id': 'C1417496', 'confidence': 0.9999999403953552}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'confirm', 'concept_id': 'C0521093', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'cellular intramuscular myxoma', 'concept_id': 'C1334260', 'confidence': 0.8910117149353027}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_166",
"caption_rating": "9"
},
{
"": "1005712",
"caption": "The patient had a history of uveitis with characteristic features of sarcoidosis.",
"image_path": "sDFjOtMAYrk_image_b22931c4-e35b-4f7b-8840-a861d97d0060.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['granuloma', 'lamina propria', 'Crohn\u2019s disease', 'infectious process', 'sarcoidosis', 'uveitis', 'granuloma', 'lamina propria', 'Crohn\u2019s disease', 'infectious process', 'sarcoidosis', 'uveitis']",
"noisy_text": " I like this place. So if you have big coalescing masses of granuloma, expanding your lamina propria, think something other than Crohn's. Think of infectious process, especially if they're necrotizing, but even if they're not, and also think of sarcoid. This patient had sarcoid. So I said, this is probably not IBD, clinicians came down, we want to look at the biopsy, of course. It turns out that they went back and talked to the patient. The patient has a history of uveitis with characteristic features that were good for sarcoidosis. Nobody knew about they treated the patient for sarcoid, re-biopsied the patient. And he was fine. There were no more granulomas on multiple repeat biopsies. And now compare those grannies with the grannies in Crohn's. So here's",
"corrected_text": " I like this place. So if you have big coalescing masses of granuloma, expanding your lamina propria, think something other than Crohn's. Think of infectious process, especially if they're necrotizing, but even if they're not, and also think of sarcoid. This patient had sarcoid. So I said, this is probably not IBD, clinicians came down, we want to look at the biopsy, of course. It turns out that they went back and talked to the patient. The patient has a history of uveitis with characteristic features that were good for sarcoidosis. Nobody knew about they treated the patient for sarcoid, re-biopsied the patient. And he was fine. There were no more granulomas on multiple repeat biopsies. And now compare those grannies with the grannies in Crohn's. So here's",
"med_umls_ids": "[[{'entity': 'Coalescing masses', 'concept_id': 'C4727092', 'confidence': 0.5960795283317566}, {'entity': 'granuloma', 'concept_id': 'C0018188', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'infectious process', 'concept_id': 'C0745283', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'Crohn\u2019s disease', 'concept_id': 'C0010346', 'confidence': 0.8916962146759033}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'history', 'concept_id': 'C0019664', 'confidence': 1.0}, {'entity': 'uveitis', 'concept_id': 'C0042164', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}], [{'entity': 'Re-biopsy', 'concept_id': 'C0005558', 'confidence': 0.6681398749351501}, {'entity': 'granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}, {'entity': 'treatment', 'concept_id': 'C0039798', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_167",
"caption_rating": "8"
},
{
"": "1008049",
"caption": "Chromatin in the nucleus can be classified as heterochromatin or euchromatin.",
"image_path": "Wiyo6taYRF4_image_8ec240a1-cd99-485c-8390-b36b49277f89.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Hematopathology', 'Neuropathology', 'Cytopathology']",
"roi_text": "['Appearance of heterochromatin and euchromatin in the nucleus.', 'Plasma cells as a reference for classifying nuclear features.', 'Example of vesicular nuclei.']",
"noisy_text": " whether it is vesicular, or it is salt and pepper-like. So these are the different nuclear features which are characterized. And how are you going to differentiate these nuclear features? So let's see some of the nuclear features. And before we move on to describe these features, I think the first thing that we should look at and understand what we are meaning by hyperchromasia and vesicularism is to look at a plasma cell. So a plasma cell is the best example, and it is the best reference where you can classify the different nuclear features. So if you look carefully, the plasma cell has got a cartwheel-like of an appearance. So it is called cartwheel because you see some areas which are darkly strained. So they are the high heterochromatin areas, that is the darkly strained areas. And then in some areas, you see that there is light straining, which is the euchromatin area. So basically, the chromatin that we see in the nucleus is of two types, heterochromatin and euchromatin. Heterochromatin is going to appear darker, whereas the euchromatin will appear lighter on the cell. So similarly, when we see here in this cell nucleus, we see that there are dark and lightly strained areas. And this is what we call as heterochromatin and euchromatin. So suppose in a cell which has mainly heterochromatin, so the entire nucleus is going to look very dark. So those are the cells that we are going to call as hyperchromatic. And if a nucleus is composed of mainly euchromatin, then it will look very lightly strained. And this is what we call as vesicular nuclei. Now to know here what is important is that in a vesicular nuclei, the nucleus is very actively dividing. So if you have not a vesicular nuclei, that in itself will tell you that the cell is very actively proliferating. So let's see one example of vesicular nuclei here. So these",
"corrected_text": " whether it is vesicular, or it is salt and pepper-like. So these are the different nuclear features which are characterized. And how are you going to differentiate these nuclear features? So let's see some of the nuclear features. And before we move on to describe these features, I think the first thing that we should look at and understand what we are meaning by hyperchromasia and vesicular nuclei is to look at a plasma cell. So a plasma cell is the best example, and it is the best reference where you can classify the different nuclear features. So if you look carefully, the plasma cell has got a cartwheel-like of an appearance. So it is called cartwheel because you see some areas which are darkly strained. So they are the high heterochromatin areas, that is the darkly strained areas. And then in some areas, you see that there is light straining, which is the euchromatin area. So basically, the chromatin that we see in the nucleus is of two types, heterochromatin and euchromatin. Heterochromatin is going to appear darker, whereas the euchromatin will appear lighter on the cell. So similarly, when we see here in this cell nucleus, we see that there are dark and lightly strained areas. And this is what we call as heterochromatin and euchromatin. So suppose in a cell which has mainly heterochromatin, so the entire nucleus is going to look very dark. So those are the cells that we are going to call as hyperchromatic. And if a nucleus is composed of mainly euchromatin, then it will look very lightly strained. And this is what we call as vesicular nuclei. Now to know here what is important is that in a vesicular nuclei, the nucleus is very actively dividing. So if you have not a vesicular nuclei, that in itself will tell you that the cell is very actively proliferating. So let's see one example of vesicular nuclei here. So these",
"med_umls_ids": "[[{'entity': 'nuclear', 'concept_id': 'C0521447', 'confidence': 1.0}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'vesicular', 'concept_id': 'C0205378', 'confidence': 1.0}, {'entity': 'salt', 'concept_id': 'C0036140', 'confidence': 1.0}, {'entity': 'pepper-like', 'concept_id': 'C2828772', 'confidence': 0.6665787696838379}], [{'entity': 'Plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'nuclear features', 'concept_id': 'C0521447', 'confidence': 0.6837654709815979}], [{'entity': 'Chromatin', 'concept_id': 'C0008546', 'confidence': 1.0}, {'entity': 'nucleus', 'concept_id': 'C0007610', 'confidence': 1.0}, {'entity': 'heterochromatin', 'concept_id': 'C0019397', 'confidence': 1.0}, {'entity': 'euchromatin', 'concept_id': 'C0059882', 'confidence': 1.0}], [{'entity': 'Hyperchromatic cells', 'concept_id': 'C0333911', 'confidence': 0.823300302028656}, {'entity': 'heterochromatin', 'concept_id': 'C0019397', 'confidence': 1.0}, {'entity': 'very dark', 'concept_id': 'C0332582', 'confidence': 0.8206402063369751}], [{'entity': 'Vesicular nuclei', 'concept_id': 'C2325471', 'confidence': 0.7651268839836121}, {'entity': 'cell', 'concept_id': 'C0007634', 'confidence': 1.0}, {'entity': 'dividing', 'concept_id': 'C0332849', 'confidence': 1.0}, {'entity': 'euchromatin', 'concept_id': 'C0059882', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1152.0",
"id": "test_168",
"caption_rating": "8"
},
{
"": "1005853",
"caption": "Inflammatory cells, including plasma cells, lymphocytes, and eosinophils, are causing expansion of the lamina propria.",
"image_path": "sDFjOtMAYrk_image_5e221488-360a-4909-aa07-cffbf8844034.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['gland dropout', 'lamina propria', 'inflammatory cells', 'plasma cells', 'lymphocytes', 'eosinophils', 'capillaries', 'epithelium', 'gland dropout', 'lamina propria', 'inflammatory cells', 'plasma cells', 'lymphocytes', 'eosinophils', 'capillaries', 'epithelium']",
"noisy_text": " you know, gland dropout here and there, but that's okay. What else? Yeah. So expansion of the lamina appropriate by inflammatory cells that includes plasma cells, lymphocytes, and some eos. And what else? Yeah, exactly. So the band interrupts inflammatory cells and capillaries, and it's not just the thickness of the band that really catches your eyes, the irregularity of it. So you don't have a thin smooth line anymore. It's just, you know, thick and irregular, just just throwing like feet down into the, into the lamina appropriate. There are also a few lymphocytes in the epithelium, but that's not the main finding. The other thing you might find",
"corrected_text": " you know, gland dropout here and there, but that's okay. What else? Yeah. So expansion of the lamina appropriate by inflammatory cells that includes plasma cells, lymphocytes, and some eos. And what else? Yeah, exactly. So the band interrupts inflammatory cells and capillaries, and it's not just the thickness of the band that really catches your eyes, the irregularity of it. So you don't have a thin smooth line anymore. It's just, you know, thick and irregular, just just throwing like feet down into the, into the lamina appropriate. There are also a few lymphocytes in the epithelium, but that's not the main finding. The other thing you might find",
"med_umls_ids": "[[{'entity': 'Inflammatory cells', 'concept_id': 'C0440752', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'expansion', 'concept_id': 'C0007595', 'confidence': 0.8664658665657043}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}], [{'entity': 'band', 'concept_id': 'C0175723', 'confidence': 1.0}, {'entity': 'inflammatory cells', 'concept_id': 'C0440752', 'confidence': 1.0}, {'entity': 'capillaries', 'concept_id': 'C0006901', 'confidence': 0.9999998807907104}, {'entity': 'irregular', 'concept_id': 'C0205271', 'confidence': 1.0}, {'entity': 'projections', 'concept_id': 'C0016538', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}], [{'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_169",
"caption_rating": "9"
},
{
"": "1006816",
"caption": "Pancreatic acinar metaplasia can also occur in the small intestine, where staining for amylase or trypsin will be positive.",
"image_path": "r7OA0Trj5hQ_image_ed71e498-cdc8-4f2a-90c3-46df67558a93.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Peritoneal cells in gastric fundic mucosa or gastric corpus mucosa', 'Acinar structures resembling pancreas in the stomach', 'Pancreatic acinar-like structures in the GIT', 'Acinar structures resembling pancreas in the stomach']",
"noisy_text": " These are the peritoneal cells. When you don't see the peritoneal cells in the gastric fundic mucosa or gastric corpus mucosa, then you have to call it as pyloric metaplasia. This is very, very important because you see it in autoimmune gastritis. Sometimes the stomach can show acinar structures resembling pancreas. Then it is known as pancreatic acinar metaplasia. This can also happen in the small intestine. There, when you do staining for amylase or trypsin, it will be positive, but on H&E itself, you can see pancreatic acinar-like structures in the GIT. Then it will become pancreatic acinar metaplasia. Here is the",
"corrected_text": " These are the peritoneal cells. When you don't see the peritoneal cells in the gastric fundic mucosa or gastric corpus mucosa, then you have to call it as pyloric metaplasia. This is very, very important because you see it in autoimmune gastritis. Sometimes the stomach can show acinar structures resembling pancreas. Then it is known as pancreatic acinar metaplasia. This can also happen in the small intestine. There, when you do staining for amylase or trypsin, it will be positive, but on H&E itself, you can see pancreatic acinar-like structures in the GIT. Then it will become pancreatic acinar metaplasia. Here is the",
"med_umls_ids": "[[{'entity': 'Absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'peritoneal cells', 'concept_id': 'C0031153', 'confidence': 0.7749612331390381}, {'entity': 'gastric fundic mucosa', 'concept_id': 'C0017136', 'confidence': 0.8429272770881653}, {'entity': 'gastric corpus mucosa', 'concept_id': 'C0735811', 'confidence': 0.9813486337661743}, {'entity': 'pyloric metaplasia', 'concept_id': 'C4288813', 'confidence': 0.8951747417449951}, {'entity': 'autoimmune gastritis', 'concept_id': 'C3887639', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'acinar structures', 'concept_id': 'C0678594', 'confidence': 0.7908228039741516}, {'entity': 'pancreas', 'concept_id': 'C0030274', 'confidence': 0.9999999403953552}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'pancreatic acinar metaplasia', 'concept_id': 'C4021967', 'confidence': 0.7844848036766052}], [{'entity': 'Pancreatic acinar metaplasia', 'concept_id': 'C4021967', 'confidence': 0.7844848036766052}, {'entity': 'small', 'concept_id': 'C0700321', 'confidence': 0.9999998807907104}, {'entity': 'intestine', 'concept_id': 'C0021853', 'confidence': 1.0}, {'entity': 'staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'amylase', 'concept_id': 'C0002712', 'confidence': 1.0}, {'entity': 'trypsin', 'concept_id': 'C0041236', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_170",
"caption_rating": "8"
},
{
"": "1008953",
"caption": "Perineurioma can be difficult to diagnose because it overlaps with low-grade fibromyxoid sarcoma histologically and on immunohistochemistry.",
"image_path": "QDb68_G1HR4_image_aeb1e9b8-0fa5-431a-89b7-ff906dab1235.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Deep soft tissue', 'Perineurioma', 'Low-grade fibromyxoid sarcoma', 'Immunohistochemistry', 'Swirling growth']",
"noisy_text": " involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is more of a difficult problem because perineurioma has a lot of overlap histologically with low-grade fibromyxoid sarcoma and also immunohistochemically. On immunostains, EMA, Clodin-1 and Glut-1 are three immunostains that will usually stain perineuriomas. The problem is that low-grade fibromyxoid sarcomas often express at least focal EMA, so that's a problem and additionally, the examples of low-grade fibromyxoid sarcoma that have dramatic swirling and whirling growth, those are the ones that have a perineurioma like pattern, the ones that mimic perineurioma. They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The",
"corrected_text": " involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is more of a difficult problem because perineurioma has a lot of overlap histologically with low-grade fibromyxoid sarcoma and also immunohistochemically. On immunostains, EMA, Clodin-1 and Glut-1 are three immunostains that will usually stain perineuriomas. The problem is that low-grade fibromyxoid sarcomas often express at least focal EMA, so that's a problem and additionally, the examples of low-grade fibromyxoid sarcoma that have dramatic swirling and whirling growth, those are the ones that have a perineurioma like pattern, the ones that mimic perineurioma. They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The",
"med_umls_ids": "[[{'entity': 'CD34', 'concept_id': 'C0054953', 'confidence': 1.0}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'deep soft tissue tumors', 'concept_id': 'C0037579', 'confidence': 0.8622524738311768}], [{'entity': 'Perineurioma', 'concept_id': 'C0751691', 'confidence': 0.9999999403953552}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'histologically', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'immunohistochemistry', 'concept_id': 'C0021044', 'confidence': 0.9999998807907104}], [{'entity': 'EMA', 'concept_id': 'C0268596', 'confidence': 0.9999999403953552}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}, {'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'immunohistochemical stains', 'concept_id': 'C4317108', 'confidence': 0.9999999403953552}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibrosarcomas', 'concept_id': 'C0016057', 'confidence': 1.0}, {'entity': 'EMA', 'concept_id': 'C0268596', 'confidence': 0.9999999403953552}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}], [{'entity': 'Low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'swirling', 'concept_id': 'C0233591', 'confidence': 0.7064549922943115}, {'entity': 'growth', 'concept_id': 'C0018270', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'express', 'concept_id': 'C0017262', 'confidence': 0.8176293969154358}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}], [{'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'reports', 'concept_id': 'C0684224', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcomas', 'concept_id': 'C1275282', 'confidence': 0.8123146891593933}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_171",
"caption_rating": "8"
},
{
"": "1009419",
"caption": "Histopathological description of an infiltrative process that looks like adenocarcinoma of the prostate with polyform and single cells in some glands.",
"image_path": "iklRyY1nBIE_image_68139a77-461a-4fd8-9b28-921455cee06c.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['Adenocarcinoma of the prostate', 'Polyform and single cells in some glands', 'Cribriform glands surrounded by basal cells']",
"noisy_text": " So you have both an infiltrative process, which looks like conventional prostate cancer. Some of the glands are polyform. Some of them are actually single cells. So this is a high-grade tumor, very busy, very busy slide. And then you have cribriform glands that look like they are surrounded by basal cells. So the question is, what do you do with this kind of morphology? What do you call this? But we'll get to that in a second. Let me show you what the cocktail looks like. Again, this is the pin three, or some call it pin four. You have",
"corrected_text": " So you have both an infiltrative process, which looks like conventional prostate cancer. Some of the glands are polyform. Some of them are actually single cells. So this is a high-grade tumor, very busy, very busy slide. And then you have cribriform glands that look like they are surrounded by basal cells. So the question is, what do you do with this kind of morphology? What do you call this? But we'll get to that in a second. Let me show you what the cocktail looks like. Again, this is the pin three, or some call it pin four. You have",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'infiltrative process', 'concept_id': 'C4527217', 'confidence': 0.8470810055732727}, {'entity': 'adenocarcinoma', 'concept_id': 'C0001418', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'polyform', 'concept_id': 'C0071571', 'confidence': 1.0}, {'entity': 'single cells', 'concept_id': 'C0037179', 'confidence': 0.7283049821853638}, {'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'cribriform glands', 'concept_id': 'C1285092', 'confidence': 0.6162902116775513}, {'entity': 'surrounded', 'concept_id': 'C1282914', 'confidence': 1.0}, {'entity': 'basal cells', 'concept_id': 'C0596155', 'confidence': 1.0}], [{'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_172",
"caption_rating": "8"
},
{
"": "1009280",
"caption": "There are lots of eosinophils, some extravasated erythrocytes, lymphocytes, and a few neutrophils in the blister cavity.",
"image_path": "hoV-JkD6Wb0_image_cfec72a9-a13d-4e4b-97e6-de1d7d2249dc.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['Subepidermal blister', 'Inflammatory cells in papillary dermis and blister cavity', 'Lymphocytes and scattered eosinophils', 'Thickening or retention of dermal papillae', 'Eosinophils, extravasated erythrocytes, lymphocytes, and neutrophils in blister cavity', 'Subepidermal blister', 'Inflammatory cells in papillary dermis and blister cavity', 'Lymphocytes and scattered eosinophils', 'Thickening or retention of dermal papillae', 'Eosinophils, extravasated erythrocytes, lymphocytes, and neutrophils in blister cavity']",
"noisy_text": " immunofluorescence. Let me flip the slide here. The staining, I'm sorry, is not so great, but one can see the presence of a subepidermal blister here. This is relatively cell-rich. There's fibrin and inflammatory cells in the papillary dermis and in the blister cavity. And if we look at the inflammatory infiltrate, there are lymphocytes and scattered eosinophils present within the dermis, some festooning or retention of the dermal papillae, and lots of eosinophils, some extravasated erythrocytes, lymphocytes, and a few neutrophils in the blister cavity. And so, you know,",
"corrected_text": " immunofluorescence. Let me flip the slide here. The staining, I'm sorry, is not so great, but one can see the presence of a subepidermal blister here. This is relatively cell-rich. There's fibrin and inflammatory cells in the papillary dermis and in the blister cavity. And if we look at the inflammatory infiltrate, there are lymphocytes and scattered eosinophils present within the dermis, some festooning or retention of the dermal papillae, and lots of eosinophils, some extravasated erythrocytes, lymphocytes, and a few neutrophils in the blister cavity. And so, you know,",
"med_umls_ids": "[[{'entity': 'subepidermal blister', 'concept_id': 'C1856956', 'confidence': 0.9338953495025635}, {'entity': 'cell-rich environment', 'concept_id': 'C0014406', 'confidence': 0.7375022768974304}, {'entity': 'fibrin', 'concept_id': 'C0015982', 'confidence': 1.0}, {'entity': 'inflammatory cells', 'concept_id': 'C0440752', 'confidence': 1.0}, {'entity': 'papillary dermis', 'concept_id': 'C0682598', 'confidence': 1.0}, {'entity': 'blister', 'concept_id': 'C0005758', 'confidence': 1.0}, {'entity': 'cavity', 'concept_id': 'C0011334', 'confidence': 1.0}], [{'entity': 'inflammatory infiltrate', 'concept_id': 'C3887644', 'confidence': 0.9999999403953552}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'scattered', 'concept_id': 'C0439742', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'thickening', 'concept_id': 'C0205400', 'confidence': 1.0}, {'entity': 'retention', 'concept_id': 'C0035280', 'confidence': 1.0}, {'entity': 'dermal', 'concept_id': 'C0221928', 'confidence': 1.0}, {'entity': 'papillae', 'concept_id': 'C4230196', 'confidence': 0.8667760491371155}], [{'entity': 'lots', 'concept_id': 'C0302148', 'confidence': 0.7982692718505859}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'extravasated', 'concept_id': 'C0015376', 'confidence': 0.868863582611084}, {'entity': 'erythrocytes', 'concept_id': 'C0014772', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'blister', 'concept_id': 'C0005758', 'confidence': 1.0}, {'entity': 'cavity', 'concept_id': 'C0011334', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_173",
"caption_rating": "8"
},
{
"": "1005484",
"caption": "The case is of prostatic adenocarcinoma with mucinous features, with strict criteria for less than or greater than 25% involvement.",
"image_path": "iklRyY1nBIE_image_482715a2-ddb7-4de9-b13d-4ac9747c562d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['Prostatic adenocarcinoma with mucinous features.']",
"noisy_text": " Yeah, so this is a nice case of prosthetic adenocarcinoma with misnose features. As some of you may be aware, there's strict criteria for that. If it's less than 25% involvement, we say misnose features. If it's greater than 25% or more, then you can actually use the term misnose adenocarcinoma with the prostate. The reason why I'm showing you this case is because here you don't see the tumor is just doing its own thing and the stroma is doing its own thing. There's no desmoplastic stromal response. There's no fluid host inflammatory response. So this is a different entity. In the past, these tumors were actually confused with one another. They thought it was the same thing decades ago. That's why in the past, misnose adenocarcinoma with the prostate were thought to be very aggressive tumors. But now we've kind of dissected these two separate entities. Of course, back then, 30 years ago, we didn't have the benefit of immunohistochemical stains. So what you're looking at right now will obviously be positive for PSA and PSAP. The original case I",
"corrected_text": " Yeah, so this is a nice case of prosthetic adenocarcinoma with mucinous features. As some of you may be aware, there's strict criteria for that. If it's less than 25% involvement, we say mucinous features. If it's greater than 25% or more, then you can actually use the term mucinous adenocarcinoma with the prostate. The reason why I'm showing you this case is because here you don't see the tumor is just doing its own thing and the stroma is doing its own thing. There's no desmoplastic stromal response. There's no fluid host inflammatory response. So this is a different entity. In the past, these tumors were actually confused with one another. They thought it was the same thing decades ago. That's why in the past, mucinous adenocarcinoma with the prostate were thought to be very aggressive tumors. But now we've kind of dissected these two separate entities. Of course, back then, 30 years ago, we didn't have the benefit of immunohistochemical stains. So what you're looking at right now will obviously be positive for PSA and PSAP. The original case I",
"med_umls_ids": "[[{'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'prostatic adenocarcinoma', 'concept_id': 'C0007112', 'confidence': 1.0}, {'entity': 'mucinous features', 'concept_id': 'C1513712', 'confidence': 0.7035756707191467}, {'entity': 'criteria', 'concept_id': 'C0243161', 'confidence': 0.9999998807907104}, {'entity': 'involvement', 'concept_id': 'C1314939', 'confidence': 1.0}], [{'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'desmoplastic reaction', 'concept_id': 'C1511789', 'confidence': 1.0}, {'entity': 'fluid', 'concept_id': 'C0005889', 'confidence': 1.0}, {'entity': 'host', 'concept_id': 'C1167395', 'confidence': 0.9999999403953552}, {'entity': 'inflammatory response', 'concept_id': 'C1155266', 'confidence': 1.0}, {'entity': 'entity', 'concept_id': 'C1551338', 'confidence': 1.0}], [{'entity': 'Mucinous adenocarcinoma', 'concept_id': 'C0007130', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'aggressive', 'concept_id': 'C0001807', 'confidence': 1.0}], [{'entity': 'Immunohistochemical stains', 'concept_id': 'C4317108', 'confidence': 0.9999999403953552}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'PSA', 'concept_id': 'C0138741', 'confidence': 1.0}, {'entity': 'PSAP', 'concept_id': 'C1418975', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_174",
"caption_rating": "7"
},
{
"": "1004590",
"caption": "Presence of melanophages with variable size and shape.",
"image_path": "8S4LeiO6Bbk_image_9667fa36-5fd9-4553-9f8c-8b3cdac2b6c1.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Melanin granules within melanophages', 'Extravasated erythrocytes', 'Increased melanin in the basilar keratinocytes.', 'Melanin granules within melanophages', 'Extravasated erythrocytes', 'Increased melanin in the basilar keratinocytes.']",
"noisy_text": " or the melanophages is variable in size and shape. Now look at the melanin granules within this melanophage, and you can see that they're much more uniform in size and shape. Now look at the melanin granules within this melanophage, and you can see that they're much more uniform in size than the hemocentauric pigment in the centaurifages. It also tends to be a little bit darker staining, but sometimes it can be very difficult, tinctorially, depending upon the staining quality, to use color to distinguish the two, better to use size and context clues. Also note here we don't have any extravasated erythrocytes here, so much more likely to be melanin, and there's an increased melanin in the basilar keratinocytes. Getting back to the case, thin epidermis, bacular",
"corrected_text": " or the melanophages is variable in size and shape. Now look at the melanin granules within this melanophage, and you can see that they're much more uniform in size and shape. Now look at the melanin granules within this melanophage, and you can see that they're much more uniform in size than the hemosiderin pigment in the centroblasts. It also tends to be a little bit darker staining, but sometimes it can be very difficult, tinctorially, depending upon the staining quality, to use color to distinguish the two, better to use size and context clues. Also note here we don't have any extravasated erythrocytes here, so much more likely to be melanin, and there's an increased melanin in the basilar keratinocytes. Getting back to the case, thin epidermis, bacular",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'melanophages', 'concept_id': 'C3280463', 'confidence': 0.9375340938568115}, {'entity': 'variable size', 'concept_id': 'C1866144', 'confidence': 0.8559831976890564}, {'entity': 'shape', 'concept_id': 'C0332479', 'confidence': 1.0}], [{'entity': 'Melanin granules', 'concept_id': 'C0230692', 'confidence': 0.9174172878265381}, {'entity': 'melanophages', 'concept_id': 'C3280463', 'confidence': 0.9375340938568115}, {'entity': 'uniform', 'concept_id': 'C0205375', 'confidence': 1.0}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'shape', 'concept_id': 'C0332479', 'confidence': 1.0}, {'entity': 'hemosiderin', 'concept_id': 'C0019113', 'confidence': 1.0}, {'entity': 'pigment', 'concept_id': 'C0031911', 'confidence': 1.0}, {'entity': 'centroblasts', 'concept_id': 'C1517735', 'confidence': 0.8281925320625305}], [{'entity': 'Increased', 'concept_id': 'C0205217', 'confidence': 1.0}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}, {'entity': 'basilar keratinocytes', 'concept_id': 'C0022567', 'confidence': 0.803361713886261}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_175",
"caption_rating": "8"
},
{
"": "1006870",
"caption": "A 44-year-old HIV-positive male with a bloody bowel movement and post-polio syndrome is being evaluated for IBD.",
"image_path": "sDFjOtMAYrk_image_b7a893c4-397f-4f99-9e3d-16a1e788f7d8.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['bloody bowel movement', 'IBD evaluation', 'architectural distortion', 'missing gland', 'bifurcation', 'crypt dropout', 'granulation tissue', 'crypt microabscesses', 'cryptitis']",
"noisy_text": " So moving along to number three, Hamar. Can you read the history please? Yeah. It's 44 years old HIV male with a bloody bowel movement and polio arthritis condition concerned about IBD. Okay. So are you gonna, are we gonna stamp him with IBD? Not yet. No, because we already saw IBD, right? So what would you say about the architectural distortion? So some sections, there's no distortion, but in some area we can see there's a lot of missing gland and the distortion of the maybe some bifurcation, right? Yeah. So some bifurcation, some crypt dropout, lots of granulation tissue, and we have plenty in the way of activity. Yeah. So I would say more than I'm used to seeing in this process. So good crypt micro abscesses and cryptitis. And then bear",
"corrected_text": " So moving along to number three, Hamar. Can you read the history please? Yeah. It's 44 years old HIV male with a bloody bowel movement and polio arthritis condition concerned about IBD. Okay. So are you gonna, are we gonna stamp him with IBD? Not yet. No, because we already saw IBD, right? So what would you say about the architectural distortion? So some sections, there's no distortion, but in some area we can see there's a lot of missing gland and the distortion of the maybe some bifurcation, right? Yeah. So some bifurcation, some crypt dropout, lots of granulation tissue, and we have plenty in the way of activity. Yeah. So I would say more than I'm used to seeing in this process. So good crypt micro abscesses and cryptitis. And then bear",
"med_umls_ids": "[[{'entity': 'HIV-positive', 'concept_id': 'C4287934', 'confidence': 0.6893086433410645}, {'entity': 'male', 'concept_id': 'C0086582', 'confidence': 1.0}, {'entity': 'bloody bowel movement', 'concept_id': 'C0151594', 'confidence': 0.9999998807907104}, {'entity': 'post-polio syndrome', 'concept_id': 'C0080040', 'confidence': 1.0}, {'entity': 'evaluated', 'concept_id': 'C0220825', 'confidence': 1.0}, {'entity': 'IBD', 'concept_id': 'C0021390', 'confidence': 1.0}], [{'entity': 'Architectural distortion', 'concept_id': 'C2826609', 'confidence': 1.0}, {'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'bifurcation', 'concept_id': 'C0184906', 'confidence': 0.9999999403953552}, {'entity': 'crypt', 'concept_id': 'C1880192', 'confidence': 1.0}, {'entity': 'dropout', 'concept_id': 'C0013135', 'confidence': 1.0}, {'entity': 'granulation tissue', 'concept_id': 'C0018180', 'confidence': 1.0}], [{'entity': 'Crypt', 'concept_id': 'C1880192', 'confidence': 1.0}, {'entity': 'microabscesses', 'concept_id': 'C0333373', 'confidence': 0.879554271697998}, {'entity': 'cryptitis', 'concept_id': 'C1394254', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_176",
"caption_rating": "8"
},
{
"": "1008512",
"caption": "Description of tumor cells with bivacuolated or multi-vacuolated appearance and bland nucleus.",
"image_path": "pBR26SS0FX8_image_e4af34da-8507-4e4f-a94a-e1471a8a8a63.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Hematopathology', 'Breast pathology']",
"roi_text": "['multi-vacuolated']",
"noisy_text": " or some of these guys are kind of bivaculated or multi-vaculated, but with a tiny little bland nucleus. See, these are multi-bubbly cells, but they just are so little, right? So the idea here is that this tumor is kind of recapitulating what fetal fat looks like during fat development in the fetus. And if you see fetal fat, which I'm sure our pediatric pathology colleague, Yan Hong can speak to, that there are times in early fetal life where the fat can have some similarity to this, that fat in embryology, my basic understanding is it starts out as a spindled precursor to adipocytes, and then it builds up a little lipid and makes a vacuole, and then can make more vacuoles sometimes, and then eventually",
"corrected_text": " or some of these guys are kind of bivacuolated or multi-vacuolated, but with a tiny little bland nucleus. See, these are multi-bubbly cells, but they just are so little, right? So the idea here is that this tumor is kind of recapitulating what fetal fat looks like during fat development in the fetus. And if you see fetal fat, which I'm sure our pediatric pathology colleague, Yan Hong can speak to, that there are times in early fetal life where the fat can have some similarity to this, that fat in embryology, my basic understanding is it starts out as a spindle precursor to adipocytes, and then it builds up a little lipid and makes a vacuole, and then can make more vacuoles sometimes, and then eventually",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'tumor cells', 'concept_id': 'C0431085', 'confidence': 1.0}, {'entity': 'bivacuolated', 'concept_id': 'C0010840', 'confidence': 0.7087458372116089}, {'entity': 'multi-vacuolated', 'concept_id': 'C1513755', 'confidence': 0.6100779175758362}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'bland nucleus', 'concept_id': 'C0007610', 'confidence': 0.7939299941062927}], [{'entity': 'Tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'fetal', 'concept_id': 'C0015965', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_177",
"caption_rating": "8"
},
{
"": "1005644",
"caption": "Absence of plasma cells within the infiltrate helps to differentiate this condition from Kaposi sarcoma.",
"image_path": "8S4LeiO6Bbk_image_53be6460-5002-409a-8303-252033435a00.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['papillary projections', 'extravasated erythrocytes', 'dilated vessels', 'enlarged endothelial cells', 'collagen bundles', 'pre-existing vascular spaces']",
"noisy_text": " into the limina. If you look around, you can see these papillary projections. There are a few extravasated erythrocytes present within the stroma. So clearly, we've got this vascular neoplasma here with these dilated endothelial line spaces, but it's got kind of a bifasic pattern. Centrally, we've got these dilated vessels, but peripheral and beneath that zone, the vessels are somewhat more compressed. They're still lined by some of the plump endothelial cells. And in these various where the vessels are compressed, they kind of appear to dissect between collagen bundles. We even have a little bit of a promontory sign here where we've got these vessels surrounding pre-existing vascular spaces. But unlike the neovascular spaces that we see in Kaposi's sarcoma, the endothelial cells here are a little more plump, and we don't have plasma cells within the infiltrate. And plasma cells within the infiltrate can be very useful in discriminating between this condition and Kaposi's sarcoma. In this particular case, also the HHV8 stain was a negative, which",
"corrected_text": " into the limina. If you look around, you can see these papillary projections. There are a few extravasated erythrocytes present within the stroma. So clearly, we've got this vascular neoplasm here with these dilated endothelial line spaces, but it's got kind of a biphasic pattern. Centrally, we've got these dilated vessels, but peripheral and beneath that zone, the vessels are somewhat more compressed. They're still lined by some of the enlarged endothelial cells. And in these various where the vessels are compressed, they kind of appear to dissect between collagen bundles. We even have a little bit of a promontory sign here where we've got these vessels surrounding pre-existing vascular spaces. But unlike the neovascularization that we see in Kaposi's sarcoma, the endothelial cells here are a little more plump, and we don't have plasma cells within the infiltrate. And plasma cells within the infiltrate can be very useful in discriminating between this condition and Kaposi's sarcoma. In this particular case, also the HHV8 stain was a negative, which",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'vascular neoplasm', 'concept_id': 'C0027668', 'confidence': 1.0}, {'entity': 'dilated endothelial line spaces', 'concept_id': 'C0014257', 'confidence': 0.6450937390327454}, {'entity': 'biphasic pattern', 'concept_id': 'C1332555', 'confidence': 1.0}], [{'entity': 'Vessels', 'concept_id': 'C0005847', 'confidence': 1.0}, {'entity': 'peripheral', 'concept_id': 'C0205100', 'confidence': 1.0}, {'entity': 'central zone', 'concept_id': 'C0458698', 'confidence': 1.0}], [{'entity': 'Endothelial cells', 'concept_id': 'C0225336', 'confidence': 1.0}, {'entity': 'enlarged', 'concept_id': 'C0442800', 'confidence': 1.0}, {'entity': 'plump', 'concept_id': 'C1836543', 'confidence': 0.7694027423858643}], [{'entity': 'Absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'differentiate', 'concept_id': 'C0205615', 'confidence': 0.9999998807907104}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'Kaposi sarcoma', 'concept_id': 'C0036220', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "758.0",
"width": "1920.0",
"id": "test_178",
"caption_rating": "8"
},
{
"": "1006807",
"caption": "Diagnosis of surface of the sclerosing epithelial neoplasm, which requires another biopsy.",
"image_path": "LlPaENuqzVQ_image_1054f018-0d38-4844-880a-e5d06f34a657.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['Eosinophilic cells with squamous morphology', 'Fibromyxoid stroma', 'Diffuse dissection throughout the dermis', 'Eosinophilic cells with squamous morphology', 'Fibromyxoid stroma', 'Diffuse dissection throughout the dermis']",
"noisy_text": " We have a diagnosis called the surface of the sclerosing epithelial neoplasm. You have to go back and take more, another biopsy. MACs often will have a little more squamoid morphology like this. Can you see those kind of eosinophilic cells? They kind of look a little bit more like squamous cells a little bit. So that favors MAC more than like a desmoplastic tricho or even like a serendoma. A serendoma usually also is obviously much smaller. You can't take a shave biopsy and get an entire serendoma out. And usually the stroma is more prominent in the serendoma. Notice that this stroma is more fibromucinous. So this thing is kind of dissecting diffusely throughout the dermis here. I don't see",
"corrected_text": " We have a diagnosis called the surface of the sclerosing epithelial neoplasm. You have to go back and take more, another biopsy. MACs often will have a little more squamous morphology like this. Can you see those kind of eosinophilic cells? They kind of look a little bit more like squamous cells a little bit. So that favors MAC more than like a desmoplastic tricholemmoma or even like a syringoma. A syringoma usually also is obviously much smaller. You can't take a shave biopsy and get an entire syringoma out. And usually the stroma is more prominent in the syringoma. Notice that this stroma is more fibromyxoid. So this thing is kind of dissecting diffusely throughout the dermis here. I don't see",
"med_umls_ids": "[[{'entity': 'Diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'sclerosing', 'concept_id': 'C0036426', 'confidence': 0.833010733127594}, {'entity': 'epithelial neoplasm', 'concept_id': 'C1368683', 'confidence': 1.0}, {'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}], [{'entity': 'Comparison', 'concept_id': 'C1707455', 'confidence': 1.0}, {'entity': 'squamous', 'concept_id': 'C1182670', 'confidence': 0.9999998807907104}, {'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}, {'entity': 'MAC', 'concept_id': 'C0009545', 'confidence': 0.9999999403953552}, {'entity': 'desmoplastic tricholemmoma', 'concept_id': 'C1275206', 'confidence': 0.9999999403953552}, {'entity': 'syringoma', 'concept_id': 'C0206673', 'confidence': 1.0}], [{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'fibromyxoid', 'concept_id': 'C0205766', 'confidence': 0.8987292051315308}, {'entity': 'stroma', 'concept_id': 'C0927195', 'confidence': 1.0}, {'entity': 'diffuse dissection', 'concept_id': 'C0205219', 'confidence': 0.7718934416770935}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_179",
"caption_rating": "7"
},
{
"": "1008756",
"caption": "Poorly differentiated cells suggest high grade malignancy and possibly lymphoma.",
"image_path": "r7OA0Trj5hQ_image_4b10e799-b399-4e91-af37-ab7b4f335854.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['poorly differentiated cells', 'lamina propria', 'lymphoma', 'CD20 IHC positive', 'poorly differentiated cells', 'lamina propria', 'lymphoma', 'CD20 IHC positive']",
"noisy_text": " Here, what is happening? Very poorly differentiated cells, high grade malignancy. Again, definitely, it is proliferative disease with the ATP. Again, invasion metastasis, we cannot see from this picture. But whenever you see this much of poorly differentiated cells in the gastric biopsy or in the colonic biopsy, and predominantly the atypical cells are situated in the lamina propria, think of lymphoma. This is a CD20 IHC, strongly positive. So this is a non-Hodgkin's lymphoma, possibly diffuse large B cell type. So we are done with surface epithelium. We are done",
"corrected_text": " Here, what is happening? Very poorly differentiated cells, high grade malignancy. Again, definitely, it is proliferative disease with the ATP. Again, invasion metastasis, we cannot see from this picture. But whenever you see this much of poorly differentiated cells in the gastric biopsy or in the colonic biopsy, and predominantly the atypical cells are situated in the lamina propria, think of lymphoma. This is a CD20 IHC, strongly positive. So this is a non-Hodgkin's lymphoma, possibly diffuse large B cell type. So we are done with surface epithelium. We are done",
"med_umls_ids": "[[{'entity': 'Poorly differentiated cells', 'concept_id': 'C0205617', 'confidence': 0.9036805629730225}, {'entity': 'lymphoma', 'concept_id': 'C0024299', 'confidence': 1.0}], [{'entity': 'CD20', 'concept_id': 'C1417326', 'confidence': 1.0}, {'entity': 'IHC', 'concept_id': 'C0021044', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'non-Hodgkin lymphoma', 'concept_id': 'C0024305', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_180",
"caption_rating": "9"
},
{
"": "1005612",
"caption": "Partial atrophy is characterized by partially atrophic glands that may be cystically dilated and have varying amounts of cytoplasm.",
"image_path": "iklRyY1nBIE_image_19dd8884-490b-48e9-b982-d85cdc717d79.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['Glands with patchy basal positivity', 'Partially atrophic glands with varying cytoplasm and cystic dilation']",
"noisy_text": " The problem is when we come to this area we were looking at earlier, you can see that some of the glands show patchy positivity for the basal cell markers, but some of them are completely negative. And to complicate things even more, some of these glands are positive for racemase or amarkar, so-called amarkar, and that causes a lot of concern. So that's why they were struggling with this case, because if you see positive racemase expression, which is typically positive in cancer, and you see negative basal cell expression, the impression people have is that you're dealing with cancer. But that's not always the case, and that's why I'm sharing this case with all of you, because this is actually a process called partial atrophy. The glands I showed you on H&E are partially atrophic. You can still see some of it here. Some of them are cystically dilated here. In some areas you can see more cytoplasm. In other areas it looks more atrophic. So even on this paint cocktail, you can appreciate the partially atrophic features. So this is a benign process. You should not call this cancer, and you should not be too generous with your atypical diagnosis either, or some people call it atypical small atrial proliferation. You should not render that diagnosis too frequently, otherwise your clinical colleagues won't trust your histologic judgment. So one has to be very careful with that. One should use that term very sparingly. So this is partial atrophy, and it's not unusual to have this kind of picture. If all the glands show patchy basal positivity, then that makes it an easy case. But some cases are tricky like this one, where some of the glands are completely negative for basal cell markers, while others are patchy positive for basal cell markers. But once you recognize on the H and E that both, you know, all these glands have similar cytologic features, both in the nucleus and the cytoplasm, that should make your life very easy. So this was a very good case of partial atrophy. I have some other cases I'll share with you very quickly. Similar scenario,",
"corrected_text": " The problem is when we come to this area we were looking at earlier, you can see that some of the glands show patchy positivity for the basal cell markers, but some of them are completely negative. And to complicate things even more, some of these glands are positive for racemase or AMACR, so-called AMACR, and that causes a lot of concern. So that's why they were struggling with this case, because if you see positive racemase expression, which is typically positive in cancer, and you see negative basal cell expression, the impression people have is that you're dealing with cancer. But that's not always the case, and that's why I'm sharing this case with all of you, because this is actually a process called partial atrophy. The glands I showed you on H&E are partially atrophic. You can still see some of it here. Some of them are cystically dilated here. In some areas you can see more cytoplasm. In other areas it looks more atrophic. So even on this paint cocktail, you can appreciate the partially atrophic features. So this is a benign process. You should not call this cancer, and you should not be too generous with your atypical diagnosis either, or some people call it atypical small atrial proliferation. You should not render that diagnosis too frequently, otherwise your clinical colleagues won't trust your histologic judgment. So one has to be very careful with that. One should use that term very sparingly. So this is partial atrophy, and it's not unusual to have this kind of picture. If all the glands show patchy basal positivity, then that makes it an easy case. But some cases are tricky like this one, where some of the glands are completely negative for basal cell markers, while others are patchy positive for basal cell markers. But once you recognize on the H and E that both, you know, all these glands have similar cytologic features, both in the nucleus and the cytoplasm, that should make your life very easy. So this was a very good case of partial atrophy. I have some other cases I'share with you very quickly. Similar scenario,",
"med_umls_ids": "[[{'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'area', 'concept_id': 'C0017446', 'confidence': 1.0}, {'entity': 'patchy', 'concept_id': 'C0205413', 'confidence': 1.0}, {'entity': 'positivity', 'concept_id': 'C4280732', 'confidence': 0.8599872589111328}, {'entity': 'basal cell', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'markers', 'concept_id': 'C0181734', 'confidence': 0.890313982963562}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'cancer', 'concept_id': 'C0006826', 'confidence': 0.9999998807907104}, {'entity': 'benign process', 'concept_id': 'C0205183', 'confidence': 0.7677057981491089}, {'entity': 'partial', 'concept_id': 'C0728938', 'confidence': 1.0}, {'entity': 'atrophy', 'concept_id': 'C0333641', 'confidence': 1.0}], [{'entity': 'Partial atrophy', 'concept_id': 'C1265892', 'confidence': 1.0}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'atrophic glands', 'concept_id': 'C5194745', 'confidence': 0.8184286952018738}, {'entity': 'cystically', 'concept_id': 'C0205207', 'confidence': 0.6787945628166199}, {'entity': 'dilated', 'concept_id': 'C0700124', 'confidence': 0.9999999403953552}, {'entity': 'cytoplasm', 'concept_id': 'C0010834', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_181",
"caption_rating": "9"
},
{
"": "1005178",
"caption": "Muscularization of the lamina propria is a criterion for mucosal prolapse in colon, particularly in solitary rectal ulcer syndrome.",
"image_path": "r7OA0Trj5hQ_image_ddce5612-5ad7-4516-a2fe-15aa78808396.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['muscularization of the lamina propria', 'gastric mucosa', 'chemical gastritis', 'antral biopsy', 'inflammation', 'muscularization of the lamina propria', 'gastric mucosa', 'chemical gastritis', 'antral biopsy', 'inflammation']",
"noisy_text": " and in cases of mucosal prolapse in colon. Remember that solitary rectal ulcer syndrome, which is totally misnomer. It is neither solitary, can be seen in other parts other than rectum. There may not be any ulcer, there is no syndrome. So the whole solitary rectal ulcer syndrome is a misnomer. But muscularization of the lamina propria is one of the criteria for mucosal prolapse that is happening in solitary rectal ulcer syndrome. And this is a gastric mucosa. Here when you see muscularization of the lamina propria, you have to think of chemical gastritis. Will it form surface changes? Lamina propria edema and muscularis mucosa coming into the lamina propria. These are the three criterias. When you see it in the anterobiopsy, think of chemical gastritis that can be seen in biliary reflux or NSAID use. Lot of inflammation results. Remember I",
"corrected_text": " and in cases of mucosal prolapse in colon. Remember that solitary rectal ulcer syndrome, which is totally misnomer. It is neither solitary, can be seen in other parts other than rectum. There may not be any ulcer, there is no syndrome. So the whole solitary rectal ulcer syndrome is a misnomer. But muscularization of the lamina propria is one of the criteria for mucosal prolapse that is happening in solitary rectal ulcer syndrome. And this is a gastric mucosa. Here when you see muscularization of the lamina propria, you have to think of chemical gastritis. Will it form surface changes? Lamina propria edema and muscularis mucosa coming into the lamina propria. These are the three criteria. When you see it in the endoscopic biopsy, think of chemical gastritis that can be seen in biliary reflux or NSAID use. Lot of inflammation results. Remember I",
"med_umls_ids": "[[{'entity': 'Muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'criterion', 'concept_id': 'C0243161', 'confidence': 1.0}, {'entity': 'mucosal prolapse', 'concept_id': 'C0034888', 'confidence': 0.826268196105957}, {'entity': 'colon', 'concept_id': 'C0009368', 'confidence': 1.0}, {'entity': 'solitary rectal ulcer syndrome', 'concept_id': 'C4274343', 'confidence': 0.9999999403953552}], [{'entity': 'Muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'gastric mucosa', 'concept_id': 'C0017136', 'confidence': 1.0}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}, {'entity': 'biliary reflux', 'concept_id': 'C0232483', 'confidence': 0.7931289672851562}, {'entity': 'NSAID', 'concept_id': 'C0003211', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_182",
"caption_rating": "9"
},
{
"": "1006396",
"caption": "Histopathological description of an epithelial tumor with interconnected cords and strands.",
"image_path": "8S4LeiO6Bbk_image_1140d29b-7b6c-44f2-84a9-7cac8ab86b82.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['epithelial tumor', 'cytoplasm', 'vesicular chromatin pattern', 'lymphocytes', 'duct formation', 'epithelial tumor', 'cytoplasm', 'vesicular chromatin pattern', 'lymphocytes', 'duct formation']",
"noisy_text": " If we move to higher power, we can see that we're dealing with an epithelial rather than a mosaicable tumor. We've got interconnected cords and strands. We have somewhat of a ribiform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of the cells are round to oval. They're fairly large. These cells have some faint eosinophilic to pale gray cytoplasm, although this cytoplasm is kind of difficult to see. Some of these cells have an evenly dispersed or vesicular chromatin pattern, and other nuclei are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and",
"corrected_text": " If we move to higher power, we can see that we're dealing with an epithelial rather than a mesenchymal tumor. We've got interconnected cords and strands. We have somewhat of a cribriform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of the cells are round to oval. They're fairly large. These cells have some faint eosinophilic to pale gray cytoplasm, although this cytoplasm is kind of difficult to see. Some of these cells have an evenly dispersed or vesicular chromatin pattern, and other nuclei are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'epithelial tumor', 'concept_id': 'C1368683', 'confidence': 0.9999999403953552}, {'entity': 'cords', 'concept_id': 'C0034869', 'confidence': 0.801885187625885}, {'entity': 'strands', 'concept_id': 'C0600383', 'confidence': 0.800572395324707}], [{'entity': 'Cribriform pattern', 'concept_id': 'C1333163', 'confidence': 1.0}, {'entity': 'loose', 'concept_id': 'C0205407', 'confidence': 1.0}, {'entity': 'edematous', 'concept_id': 'C0013604', 'confidence': 1.0}, {'entity': 'vascular stroma', 'concept_id': 'C0005847', 'confidence': 0.8046398758888245}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'cell types', 'concept_id': 'C0007634', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'eosinophilic', 'concept_id': 'C0333930', 'confidence': 1.0}, {'entity': 'pale', 'concept_id': 'C0030232', 'confidence': 1.0}, {'entity': 'gray cytoplasm', 'concept_id': 'C0010834', 'confidence': 0.8177905678749084}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'duct', 'concept_id': 'C0687028', 'confidence': 1.0}, {'entity': 'formation', 'concept_id': 'C0220781', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_183",
"caption_rating": "8"
},
{
"": "1005000",
"caption": "MAC is a neoplasm that is diffuse in nature and does not show a lot of mitoses or individual cellular atypia.",
"image_path": "LlPaENuqzVQ_image_ee0713b0-bfee-421c-ac8e-df38259a6a92.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['MAC looks like a syringoma.', 'MAC looks like a syringoma.']",
"noisy_text": " And basically, another name for MAC that I actually like better is syringomatous carcinoma because it looks like a syringoma. And if you look at the individual cells, usually you don't see a lot of mitoses. There's not a lot of individual cellular atypia, not a lot of pleomorphism. It's really a neoplasm that causes problems because of its diffuse nature. Some cancers are aggressive because they metastasize. Some are more aggressive because they just like crab. They just gradually erode everything and they just destroy everything in their path. And so this is more that sort of thing and it goes deep. And one other thing that you look for when you're",
"corrected_text": " And basically, another name for MAC that I actually like better is syringomatous carcinoma because it looks like a syringoma. And if you look at the individual cells, usually you don't see a lot of mitoses. There's not a lot of individual cellular atypia, not a lot of pleomorphism. It's really a neoplasm that causes problems because of its diffuse nature. Some cancers are aggressive because they metastasize. Some are more aggressive because they just like crab. They just gradually erode everything and they just destroy everything in their path. And so this is more that sort of thing and it goes deep. And one other thing that you look for when you're",
"med_umls_ids": "[[{'entity': 'MAC', 'concept_id': 'C0009545', 'confidence': 0.9999999403953552}, {'entity': 'Mycobacterium avium complex', 'concept_id': 'C0026914', 'confidence': 1.0}, {'entity': 'syringomatous carcinoma', 'concept_id': 'C0346027', 'confidence': 1.0}, {'entity': 'syringoma', 'concept_id': 'C0206673', 'confidence': 1.0}], [{'entity': 'MAC', 'concept_id': 'C0009545', 'confidence': 0.9999999403953552}, {'entity': 'neoplasm', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'diffuse', 'concept_id': 'C0205219', 'confidence': 1.0}, {'entity': 'nature', 'concept_id': 'C0349590', 'confidence': 1.0}, {'entity': 'mitoses', 'concept_id': 'C0026255', 'confidence': 1.0}, {'entity': 'cellular atypia', 'concept_id': 'C0333865', 'confidence': 0.9999999403953552}], [{'entity': 'MAC', 'concept_id': 'C0009545', 'confidence': 0.9999999403953552}, {'entity': 'deep cancer', 'concept_id': 'C0006826', 'confidence': 0.6357579231262207}, {'entity': 'destroys', 'concept_id': 'C0681205', 'confidence': 0.6218703985214233}, {'entity': 'path', 'concept_id': 'C1705483', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_184",
"caption_rating": "8"
},
{
"": "1007417",
"caption": "The patient has a positive digital rectal examination and elevated PSA levels, which may indicate prostate cancer.",
"image_path": "iklRyY1nBIE_image_9901ed20-bb96-4693-9cc1-725d57dbf57d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['Adenocarcinoma of the prostate', 'Necrosis', 'Positive digital rectal examination', 'Elevated PSA levels']",
"noisy_text": " mixed with conventional prostate cancer, which you have. A little bit of this is conventional here. And then you can have other variants or other patterns. You can see this is more conventional here. And you even have necrosis there. So this is basically bad news for this patient. All right, so we're going to move to case five. Case five is a 56-year-old man who presented with a positive digital record examination and elevated PSA levels. So as you can see, the histories are now beginning to overlap. They are beginning to sound very similar to one another, even though we are seeing different things histologically. So this",
"corrected_text": " mixed with conventional prostate cancer, which you have. A little bit of this is conventional here. And then you can have other variants or other patterns. You can see this is more conventional here. And you even have necrosis there. So this is basically bad news for this patient. All right, so we're going to move to case five. Case five is a 56-year-old man who presented with a positive digital record examination and elevated PSA levels. So as you can see, the histories are now beginning to overlap. They are beginning to sound very similar to one another, even though we are seeing different things histologically. So this",
"med_umls_ids": "[[{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'adenocarcinoma', 'concept_id': 'C0001418', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'conventional', 'concept_id': 'C0439858', 'confidence': 1.0}, {'entity': 'necrotic', 'concept_id': 'C0027540', 'confidence': 1.0}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'digital rectal examination', 'concept_id': 'C0199900', 'confidence': 1.0}, {'entity': 'elevated', 'concept_id': 'C0205250', 'confidence': 0.9999999403953552}, {'entity': 'PSA', 'concept_id': 'C0138741', 'confidence': 1.0}, {'entity': 'levels', 'concept_id': 'C0441889', 'confidence': 1.0}, {'entity': 'prostate cancer', 'concept_id': 'C0376358', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_185",
"caption_rating": "9"
},
{
"": "1006000",
"caption": "Example of metastatic malignant melanoma",
"image_path": "LlPaENuqzVQ_image_3bd0e420-a340-469e-af56-64910f8d2241.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['multiple nodular aggregations', 'metastatic malignant melanoma']",
"noisy_text": " strands between them and collagen bubbles, which we don't see here. Here's another metastatic neoplasm. And this is nice. You get multiple sort of nodular aggregations in the dermis. And this is an example of metastatic malignant melanoma. So, again, if you see neoplastic cells, there's several different ways you get metastases to the skin. One is like multiple little nodular aggregations, large nodular aggregations. You can get the cords and strands between them and collagen. So occasionally you get like intravascular, both if you're lymphatic or also intro, you know, blood vessel neoplastic cells, those might have been in lymphatics,",
"corrected_text": " strands between them and collagen bubbles, which we don't see here. Here's another metastatic neoplasm. And this is nice. You get multiple sort of nodular aggregations in the dermis. And this is an example of metastatic malignant melanoma. So, again, if you see neoplastic cells, there's several different ways you get metastases to the skin. One is like multiple little nodular aggregations, large nodular aggregations. You can get the cords and strands between them and collagen. So occasionally you get like intravascular, both if you're lymphatic or also intro, you know, blood vessel neoplastic cells, those might have been in lymphatics,",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'metastatic neoplasms', 'concept_id': 'C1522435', 'confidence': 0.9036427140235901}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}], [{'entity': 'metastatic malignant melanoma', 'concept_id': 'C0860594', 'confidence': 1.0}], [{'entity': 'metastases', 'concept_id': 'C0027627', 'confidence': 1.0}, {'entity': 'skin', 'concept_id': 'C0444099', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_186",
"caption_rating": "7"
},
{
"": "1005634",
"caption": "The tumor has a bland appearance and a pink fibrous background that can be confused with other fibrous fibroblastic tumors like desmoid fibromatosis.",
"image_path": "QDb68_G1HR4_image_b5b8cc71-9765-4cdf-b010-54f0249e82de.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['fibrous areas']",
"noisy_text": " bland appearance and the pink fibrous background can easily get confused with other things. Also desmoid fibromatosis, I've got a video about that, I'll put a link down in the video description below, you can watch that if you're curious about desmoid tumors. Those are all fibrous fibroblastic tumors that are tumors with a fibroblastic looking background that can get confused with this tumor. So let's go down and look closer here and see what we have. So let's look at the fibrous areas first. The fibrous",
"corrected_text": " bland appearance and the pink fibrous background can easily get confused with other things. Also desmoid fibromatosis, I've got a video about that, I'll put a link down in the video description below, you can watch that if you're curious about desmoid tumors. Those are all fibrous fibroblastic tumors that are tumors with a fibroblastic looking background that can get confused with this tumor. So let's go down and look closer here and see what we have. So let's look at the fibrous areas first. The fibrous",
"med_umls_ids": "[[{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'bland', 'concept_id': 'C0227475', 'confidence': 0.7435316443443298}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'pink fibrous', 'concept_id': 'C0439709', 'confidence': 0.7378140091896057}, {'entity': 'fibrous fibroblastic tumors', 'concept_id': 'C0206643', 'confidence': 0.861375093460083}, {'entity': 'desmoid', 'concept_id': 'C0079218', 'confidence': 1.0}, {'entity': 'fibromatosis', 'concept_id': 'C0016048', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_187",
"caption_rating": "8"
},
{
"": "1006676",
"caption": "The tumor has an aggressive appearance and elicits a desmoplastic reaction and host inflammatory response.",
"image_path": "iklRyY1nBIE_image_6d7dbac7-6b49-4eb2-a075-c6a4db9d032d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['Pancreatobiliary tract look', 'Prostatic adenocarcinoma with mucinous features', 'Desmoplastic reaction', 'Host inflammatory response', 'Pancreatobiliary tract look', 'Prostatic adenocarcinoma with mucinous features', 'Desmoplastic reaction', 'Host inflammatory response']",
"noisy_text": " So this is the way it starts. For those of us who also sign out GI, it almost has a pancreatobiliary look in areas. So these are aggressive. The reason why I'm telling you that is these are aggressive tumors. When I show you an example of prosthetic adenocarcinoma with misnose features, you will see that it doesn't elicit a desmoplastic stromal response or even a host inflammatory response. But this tumor does. So let me show you some examples of those. Yeah, so this is a nice case of prosthetic adenocarcinoma with misnose features. As some of you may",
"corrected_text": " So this is the way it starts. For those of us who also sign out GI, it almost has a pancreatobiliary tract look in areas. So these are aggressive. The reason why I'm telling you that is these are aggressive tumors. When I show you an example of prostatic adenocarcinoma with mucinous features, you will see that it doesn't elicit a desmoplastic stromal response or even a host inflammatory response. But this tumor does. So let me show you some examples of those. Yeah, so this is a nice case of prostatic adenocarcinoma with mucinous features. As some of you may",
"med_umls_ids": "[[{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'aggressive', 'concept_id': 'C0001807', 'confidence': 1.0}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'desmoplastic reaction', 'concept_id': 'C1511789', 'confidence': 1.0}, {'entity': 'host', 'concept_id': 'C1167395', 'confidence': 0.9999999403953552}, {'entity': 'inflammatory response', 'concept_id': 'C1155266', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_188",
"caption_rating": "9"
},
{
"": "1004211",
"caption": "There are several melanocytes present, some forming nests and extending into the upper portions of the matrix in a pagetoid pattern.",
"image_path": "8S4LeiO6Bbk_image_5f174254-0490-4295-ae0c-e926e4473247.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['nail bed', 'matrix epithelium', 'melanocytes forming nests', 'pagetoid pattern', 'basal layer of the matrix', 'upper portions of the matrix']",
"noisy_text": " we've got nail bed and matricle epithelium. I believe this must be some nail fold, a portion of the nail fold, and then in the bottom piece of tissue in these sections we actually have matricle epithelium and you can see the rete or somewhat hyperplastic. And on higher power examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matricle epithelium in the matricle layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that",
"corrected_text": " we've got nail bed and matrix epithelium. I believe this must be some nail fold, a portion of the nail fold, and then in the bottom piece of tissue in these sections we actually have matrix epithelium and you can see the rete or somewhat hyperplastic. And on higher power examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matrix epithelium in the matrix layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that",
"med_umls_ids": "[[{'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'nail', 'concept_id': 'C0027342', 'confidence': 1.0}, {'entity': 'matrix epithelium', 'concept_id': 'C0014609', 'confidence': 0.7584323883056641}], [{'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'nests', 'concept_id': 'C0035253', 'confidence': 0.7275967001914978}, {'entity': 'upper portions', 'concept_id': 'C0449719', 'confidence': 0.6251541972160339}, {'entity': 'matrix', 'concept_id': 'C0331858', 'confidence': 1.0}, {'entity': 'pagetoid', 'concept_id': 'C1518847', 'confidence': 0.8801172375679016}, {'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}], [{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'matrix layer', 'concept_id': 'C0331858', 'confidence': 0.71736741065979}, {'entity': 'suspicious', 'concept_id': 'C0750493', 'confidence': 1.0}, {'entity': 'melanoma', 'concept_id': 'C0025202', 'confidence': 1.0}, {'entity': 'in situ', 'concept_id': 'C0444498', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_189",
"caption_rating": "9"
},
{
"": "1008446",
"caption": "EMA, Clodin-1, and Glut-1 are immunohistochemical stains that can help diagnose perineuriomas, but low-grade fibrosarcomas can also express EMA and Clodin-1.",
"image_path": "QDb68_G1HR4_image_8772a4d0-5e6a-4322-9ff2-d521cda51a2d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Deep soft tissue', 'Perineurioma', 'Low-grade fibromyxoid sarcoma', 'Immunohistochemistry', 'Swirling growth', 'Deep soft tissue', 'Perineurioma', 'Low-grade fibromyxoid sarcoma', 'Immunohistochemistry', 'Swirling growth']",
"noisy_text": " involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is more of a difficult problem because perineurioma has a lot of overlap histologically with low-grade fibromyxoid sarcoma and also immunohistochemically. On immunostains, EMA, Clodin-1 and Glut-1 are three immunostains that will usually stain perineuriomas. The problem is that low-grade fibromyxoid sarcomas often express at least focal EMA, so that's a problem and additionally, the examples of low-grade fibromyxoid sarcoma that have dramatic swirling and whirling growth, those are the ones that have a perineurioma like pattern, the ones that mimic perineurioma. They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The",
"corrected_text": " involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is more of a difficult problem because perineurioma has a lot of overlap histologically with low-grade fibromyxoid sarcoma and also immunohistochemically. On immunostains, EMA, Clodin-1 and Glut-1 are three immunostains that will usually stain perineuriomas. The problem is that low-grade fibromyxoid sarcomas often express at least focal EMA, so that's a problem and additionally, the examples of low-grade fibromyxoid sarcoma that have dramatic swirling and whirling growth, those are the ones that have a perineurioma like pattern, the ones that mimic perineurioma. They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The",
"med_umls_ids": "[[{'entity': 'CD34', 'concept_id': 'C0054953', 'confidence': 1.0}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'deep soft tissue tumors', 'concept_id': 'C0037579', 'confidence': 0.8622524738311768}], [{'entity': 'Perineurioma', 'concept_id': 'C0751691', 'confidence': 0.9999999403953552}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'histologically', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'immunohistochemistry', 'concept_id': 'C0021044', 'confidence': 0.9999998807907104}], [{'entity': 'EMA', 'concept_id': 'C0268596', 'confidence': 0.9999999403953552}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}, {'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'immunohistochemical stains', 'concept_id': 'C4317108', 'confidence': 0.9999999403953552}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibrosarcomas', 'concept_id': 'C0016057', 'confidence': 1.0}, {'entity': 'EMA', 'concept_id': 'C0268596', 'confidence': 0.9999999403953552}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}], [{'entity': 'Low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'swirling', 'concept_id': 'C0233591', 'confidence': 0.7064549922943115}, {'entity': 'growth', 'concept_id': 'C0018270', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'express', 'concept_id': 'C0017262', 'confidence': 0.8176293969154358}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}], [{'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'reports', 'concept_id': 'C0684224', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcomas', 'concept_id': 'C1275282', 'confidence': 0.8123146891593933}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_190",
"caption_rating": "8"
},
{
"": "1008051",
"caption": "Vesicular nuclei indicate that the cell is actively dividing and composed mainly of euchromatin.",
"image_path": "Wiyo6taYRF4_image_8ec240a1-cd99-485c-8390-b36b49277f89.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Hematopathology', 'Neuropathology', 'Cytopathology']",
"roi_text": "['Appearance of heterochromatin and euchromatin in the nucleus.', 'Plasma cells as a reference for classifying nuclear features.', 'Example of vesicular nuclei.']",
"noisy_text": " whether it is vesicular, or it is salt and pepper-like. So these are the different nuclear features which are characterized. And how are you going to differentiate these nuclear features? So let's see some of the nuclear features. And before we move on to describe these features, I think the first thing that we should look at and understand what we are meaning by hyperchromasia and vesicularism is to look at a plasma cell. So a plasma cell is the best example, and it is the best reference where you can classify the different nuclear features. So if you look carefully, the plasma cell has got a cartwheel-like of an appearance. So it is called cartwheel because you see some areas which are darkly strained. So they are the high heterochromatin areas, that is the darkly strained areas. And then in some areas, you see that there is light straining, which is the euchromatin area. So basically, the chromatin that we see in the nucleus is of two types, heterochromatin and euchromatin. Heterochromatin is going to appear darker, whereas the euchromatin will appear lighter on the cell. So similarly, when we see here in this cell nucleus, we see that there are dark and lightly strained areas. And this is what we call as heterochromatin and euchromatin. So suppose in a cell which has mainly heterochromatin, so the entire nucleus is going to look very dark. So those are the cells that we are going to call as hyperchromatic. And if a nucleus is composed of mainly euchromatin, then it will look very lightly strained. And this is what we call as vesicular nuclei. Now to know here what is important is that in a vesicular nuclei, the nucleus is very actively dividing. So if you have not a vesicular nuclei, that in itself will tell you that the cell is very actively proliferating. So let's see one example of vesicular nuclei here. So these",
"corrected_text": " whether it is vesicular, or it is salt and pepper-like. So these are the different nuclear features which are characterized. And how are you going to differentiate these nuclear features? So let's see some of the nuclear features. And before we move on to describe these features, I think the first thing that we should look at and understand what we are meaning by hyperchromasia and vesicular nuclei is to look at a plasma cell. So a plasma cell is the best example, and it is the best reference where you can classify the different nuclear features. So if you look carefully, the plasma cell has got a cartwheel-like of an appearance. So it is called cartwheel because you see some areas which are darkly strained. So they are the high heterochromatin areas, that is the darkly strained areas. And then in some areas, you see that there is light straining, which is the euchromatin area. So basically, the chromatin that we see in the nucleus is of two types, heterochromatin and euchromatin. Heterochromatin is going to appear darker, whereas the euchromatin will appear lighter on the cell. So similarly, when we see here in this cell nucleus, we see that there are dark and lightly strained areas. And this is what we call as heterochromatin and euchromatin. So suppose in a cell which has mainly heterochromatin, so the entire nucleus is going to look very dark. So those are the cells that we are going to call as hyperchromatic. And if a nucleus is composed of mainly euchromatin, then it will look very lightly strained. And this is what we call as vesicular nuclei. Now to know here what is important is that in a vesicular nuclei, the nucleus is very actively dividing. So if you have not a vesicular nuclei, that in itself will tell you that the cell is very actively proliferating. So let's see one example of vesicular nuclei here. So these",
"med_umls_ids": "[[{'entity': 'nuclear', 'concept_id': 'C0521447', 'confidence': 1.0}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'vesicular', 'concept_id': 'C0205378', 'confidence': 1.0}, {'entity': 'salt', 'concept_id': 'C0036140', 'confidence': 1.0}, {'entity': 'pepper-like', 'concept_id': 'C2828772', 'confidence': 0.6665787696838379}], [{'entity': 'Plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'nuclear features', 'concept_id': 'C0521447', 'confidence': 0.6837654709815979}], [{'entity': 'Chromatin', 'concept_id': 'C0008546', 'confidence': 1.0}, {'entity': 'nucleus', 'concept_id': 'C0007610', 'confidence': 1.0}, {'entity': 'heterochromatin', 'concept_id': 'C0019397', 'confidence': 1.0}, {'entity': 'euchromatin', 'concept_id': 'C0059882', 'confidence': 1.0}], [{'entity': 'Hyperchromatic cells', 'concept_id': 'C0333911', 'confidence': 0.823300302028656}, {'entity': 'heterochromatin', 'concept_id': 'C0019397', 'confidence': 1.0}, {'entity': 'very dark', 'concept_id': 'C0332582', 'confidence': 0.8206402063369751}], [{'entity': 'Vesicular nuclei', 'concept_id': 'C2325471', 'confidence': 0.7651268839836121}, {'entity': 'cell', 'concept_id': 'C0007634', 'confidence': 1.0}, {'entity': 'dividing', 'concept_id': 'C0332849', 'confidence': 1.0}, {'entity': 'euchromatin', 'concept_id': 'C0059882', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1152.0",
"id": "test_191",
"caption_rating": "9"
},
{
"": "1009367",
"caption": "Lymphoid follicles are abnormal in the stomach and seen in chronic gastroenteritis.",
"image_path": "r7OA0Trj5hQ_image_1646d5e3-edbd-491c-919a-3bbbe655dde9.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Lymphoid follicles in the stomach']",
"noisy_text": " So this is chronic colitis with activity. These are granulomas in the lamina propria. Think of tuberculosis in India, sarcoidosis, fungal infections, or idiopathic, or foreign bodies. So those are all the four main things. Any granuloma, infectious or non-infectious. When infectious, is it necrotizing or non-necrotizing? Lymphoid follicles, again, abnormal in the stomach. And they are seen in the lamina propria, chronic gastroenteritis. You can all identify these beautiful inclusions. And some cytoplasmic inclusions also, nuclear and",
"corrected_text": " So this is chronic colitis with activity. These are granulomas in the lamina propria. Think of tuberculosis in India, sarcoidosis, fungal infections, or idiopathic, or foreign bodies. So those are all the four main things. Any granuloma, infectious or non-infectious. When infectious, is it necrotizing or non-necrotizing? Lymphoid follicles, again, abnormal in the stomach. And they are seen in the lamina propria, chronic gastroenteritis. You can all identify these beautiful inclusions. And some cytoplasmic inclusions also, nuclear and",
"med_umls_ids": "[[{'entity': 'Chronic colitis', 'concept_id': 'C0267375', 'confidence': 0.9999999403953552}, {'entity': 'activity', 'concept_id': 'C0026606', 'confidence': 1.0}, {'entity': 'granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}], [{'entity': 'Granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}, {'entity': 'tuberculosis', 'concept_id': 'C0041296', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'fungal infections', 'concept_id': 'C0026946', 'confidence': 1.0}, {'entity': 'idiopathic', 'concept_id': 'C0332240', 'confidence': 0.9999998807907104}, {'entity': 'foreign bodies', 'concept_id': 'C0016542', 'confidence': 1.0}], [{'entity': 'Lymphoid follicles', 'concept_id': 'C0229654', 'confidence': 0.9380706548690796}, {'entity': 'abnormal', 'concept_id': 'C0205161', 'confidence': 1.0}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'chronic gastroenteritis', 'concept_id': 'C0017160', 'confidence': 0.8353270292282104}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_192",
"caption_rating": "8"
},
{
"": "1004480",
"caption": "Assessment of fibrosis in the lamina propria is important for determining chronicity.",
"image_path": "r7OA0Trj5hQ_image_4a7224df-be04-4c7f-95eb-7144de15a124.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['fibrosis in the lamina propria']",
"noisy_text": " Whereas here, it's involving more endothelium. This is a special strain, gastric biopsy again. You see a lot of macrophages with the pink stuff. This is a AFB strain. Whenever you see a lot of pink stuff in the lamina propria within the macrophages, think of mycobacterium, AVM, intracellular. Then now, we have to assess the fibrosis in the lamina propria. Again, fibrosis is one of the chronicity criteria. This is normal glands, whereas here, gastric mucosa is the increased reticuline rich. Another thing you have to remember, reticuline strain, you have",
"corrected_text": " Whereas here, it's involving more endothelium. This is a special strain, gastric biopsy again. You see a lot of macrophages with the pink stuff. This is a AFB strain. Whenever you see a lot of pink stuff in the lamina propria within the macrophages, think of mycobacterium, AVM, intracellular. Then now, we have to assess the fibrosis in the lamina propria. Again, fibrosis is one of the chronicity criteria. This is normal glands, whereas here, gastric mucosa is the increased reticuline rich. Another thing you have to remember, reticulin stain, you have",
"med_umls_ids": "[[{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'involvement', 'concept_id': 'C1314939', 'confidence': 1.0}, {'entity': 'endothelium', 'concept_id': 'C0014257', 'confidence': 0.9999998807907104}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'macrophages', 'concept_id': 'C0024432', 'confidence': 1.0}, {'entity': 'pink stuff', 'concept_id': 'C0332585', 'confidence': 0.5879191756248474}, {'entity': 'AFB', 'concept_id': 'C0483226', 'confidence': 1.0}, {'entity': 'strain', 'concept_id': 'C0080194', 'confidence': 1.0}, {'entity': 'mycobacterium infection', 'concept_id': 'C0026918', 'confidence': 1.0}], [{'entity': 'Assessment', 'concept_id': 'C0031809', 'confidence': 1.0}, {'entity': 'fibrosis', 'concept_id': 'C0016059', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'chronicity', 'concept_id': 'C0547045', 'confidence': 1.0}], [{'entity': 'Increased', 'concept_id': 'C0205217', 'confidence': 1.0}, {'entity': 'reticuline', 'concept_id': 'C0073098', 'confidence': 1.0}, {'entity': 'gastric mucosa', 'concept_id': 'C0017136', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_193",
"caption_rating": "8"
},
{
"": "1006140",
"caption": "Cytokeratin will be positive in signet cell carcinoma.",
"image_path": "r7OA0Trj5hQ_image_421e06a2-6158-4ad4-b890-f2c0737d7041.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Gastric xanthoma', 'Signet ring cells', 'Poorly differentiated signet cell carcinoma', 'Gastric xanthoma', 'Signet ring cells', 'Poorly differentiated signet cell carcinoma', 'Gastric xanthoma', 'Signet ring cells', 'Poorly differentiated signet cell carcinoma']",
"noisy_text": " And so this is a gastric xanthoma. Here, it is more like a signet cells. And when you do cytokeratin, it will all be positive. So it's a poorly differentiated signet cell carcinoma. And there are only three types of pathologists in the world. And this, I got it again from Twitter, I think from Sanjay Bhavatiya, pathologists who missed signet cells, pathologists who are missing the signet cells, pathologists who will be missing the signet cell carcinoma. So it's a very, very, very difficult condition. We have to keep our eyes wide. Leave open to",
"corrected_text": " And so this is a gastric xanthoma. Here, it is more like a signet cells. And when you do cytokeratin, it will all be positive. So it's a poorly differentiated signet cell carcinoma. And there are only three types of pathologists in the world. And this, I got it again from Twitter, I think from Sanjay Bhavatiya, pathologists who missed signet cells, pathologists who are missing the signet cells, pathologists who will be missing the signet cell carcinoma. So it's a very, very, very difficult condition. We have to keep our eyes wide. Leave open to",
"med_umls_ids": "[[{'entity': 'Gastric xanthoma', 'concept_id': 'C1282522', 'confidence': 1.0}, {'entity': 'signet cell carcinoma', 'concept_id': 'C0206696', 'confidence': 0.9410539865493774}], [{'entity': 'Cytokeratin', 'concept_id': 'C0010803', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'signet cell carcinoma', 'concept_id': 'C0206696', 'confidence': 0.9410539865493774}], [{'entity': 'Signet cell carcinoma', 'concept_id': 'C0206696', 'confidence': 0.9410539865493774}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_194",
"caption_rating": "8"
},
{
"": "1005259",
"caption": "Description of combined nevi, which are melanocytic tumors characterized by a benign nevus and a population of epithelial-like melanocytes.",
"image_path": "8S4LeiO6Bbk_image_7272172a-5f4b-406f-91fe-94b2accbec68.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['population of banal appearing melanocytes', 'balloon melanocytes', 'benign nevus', 'cellular blue nevus', 'population of banal appearing melanocytes', 'balloon melanocytes', 'benign nevus', 'cellular blue nevus']",
"noisy_text": " Those are combined nevi because you usually have a population of banal appearing melanocytes and balloon melanocytes. At that point, inactivated melanocytic tumors are frequently combined nevi, commonly characterized by banal nevus and a population of very epithelial spits like melanocytes. So anyway, all possible combinations are... And in actuality, a deep penetrating nevus is frequently combined nevus with a combination of banal nevus and what looks oftentimes like a cellular blue nevus. So anyway, this is a combined melanocytic nevus. So that's all I have for you. And if you have any questions, again, please feel free to reach out. You can email me at tdavis.sagesdx.com or education at sagesdx.com. Thank you very much. We're always looking for suggestions. So if you have any topics that you would like to have covered, please feel free to shoot me an email. Thanks so much for your attention. Have a good evening.",
"corrected_text": " Those are combined nevi because you usually have a population of banal appearing melanocytes and balloon melanocytes. At that point, inactivated melanocytic tumors are frequently combined nevi, commonly characterized by benign nevus and a population of very epithelial spits like melanocytes. So anyway, all possible combinations are... And in actuality, a deep penetrating nevus is frequently combined nevus with a combination of benign nevus and what looks oftentimes like a cellular blue nevus. So anyway, this is a combined melanocytic nevus. So that's all I have for you. And if you have any questions, again, please feel free to reach out. You can email me at tdavis.sagesdx.com or education at sagesdx.com. Thank you very much. We're always looking for suggestions. So if you have any topics that you would like to have covered, please feel free to shoot me an email. Thanks so much for your attention. Have a good evening.",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'combined', 'concept_id': 'C0205195', 'confidence': 1.0}, {'entity': 'nevi', 'concept_id': 'C0027960', 'confidence': 1.0}, {'entity': 'melanocytic tumors', 'concept_id': 'C0349501', 'confidence': 0.7923030257225037}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'benign nevus', 'concept_id': 'C1456781', 'confidence': 1.0}, {'entity': 'population', 'concept_id': 'C0032659', 'confidence': 1.0}, {'entity': 'epithelial-like', 'concept_id': 'C0334254', 'confidence': 0.6890533566474915}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_195",
"caption_rating": "8"
},
{
"": "1007476",
"caption": "Melanin granules within melanophages are more uniform in size and shape compared to hemosiderin pigment in centroblasts.",
"image_path": "8S4LeiO6Bbk_image_7ca36f0b-8c63-4e76-92ea-83ccb8fe5719.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Melanin granules within melanophages']",
"noisy_text": " or the melanophages is variable in size and shape. Now look at the melanin granules within this melanophage, and you can see that they're much more uniform in size and shape. Now look at the melanin granules within this melanophage, and you can see that they're much more uniform in size than the hemocentauric pigment in the centaurifages. It also tends to be a little bit darker staining, but sometimes it can be very difficult, tinctorially, depending upon the staining quality, to use color to distinguish the two, better to use size and context clues. Also note here we don't have any extravasated erythrocytes here, so much more likely to be melanin, and there's an increased melanin in the basilar keratinocytes. Getting back to the case, thin epidermis, bacular",
"corrected_text": " or the melanophages is variable in size and shape. Now look at the melanin granules within this melanophage, and you can see that they're much more uniform in size and shape. Now look at the melanin granules within this melanophage, and you can see that they're much more uniform in size than the hemosiderin pigment in the centroblasts. It also tends to be a little bit darker staining, but sometimes it can be very difficult, tinctorially, depending upon the staining quality, to use color to distinguish the two, better to use size and context clues. Also note here we don't have any extravasated erythrocytes here, so much more likely to be melanin, and there's an increased melanin in the basilar keratinocytes. Getting back to the case, thin epidermis, bacular",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'melanophages', 'concept_id': 'C3280463', 'confidence': 0.9375340938568115}, {'entity': 'variable size', 'concept_id': 'C1866144', 'confidence': 0.8559831976890564}, {'entity': 'shape', 'concept_id': 'C0332479', 'confidence': 1.0}], [{'entity': 'Melanin granules', 'concept_id': 'C0230692', 'confidence': 0.9174172878265381}, {'entity': 'melanophages', 'concept_id': 'C3280463', 'confidence': 0.9375340938568115}, {'entity': 'uniform', 'concept_id': 'C0205375', 'confidence': 1.0}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'shape', 'concept_id': 'C0332479', 'confidence': 1.0}, {'entity': 'hemosiderin', 'concept_id': 'C0019113', 'confidence': 1.0}, {'entity': 'pigment', 'concept_id': 'C0031911', 'confidence': 1.0}, {'entity': 'centroblasts', 'concept_id': 'C1517735', 'confidence': 0.8281925320625305}], [{'entity': 'Increased', 'concept_id': 'C0205217', 'confidence': 1.0}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}, {'entity': 'basilar keratinocytes', 'concept_id': 'C0022567', 'confidence': 0.803361713886261}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_196",
"caption_rating": "8"
},
{
"": "1005286",
"caption": "Loss of cellular polarity is seen in the sample.",
"image_path": "r7OA0Trj5hQ_image_02a9f76c-0858-4d40-868a-9163d61564ef.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['nuclei touching the top of the apical membrane', 'prominent nuclei', 'loss of cellular polarity', 'cribriform', 'micropapillary process']",
"noisy_text": " Can you all see the nuclei touching the top of the apical membrane? And see the prominent nuclei. And see the nuclei are running in different directions. This nuclei is running in this direction, whereas this nuclei is running in this direction. This nuclei is running in this direction. So there is loss of polarity. Okay, so here also it is stratified, reaching up to the top, and it is showing loss of polarity. And see the cribriformic. And this is a micropapillary process. Since it's a high power, you are not able to appreciate it better. I will show it to you in the other pictures. But here",
"corrected_text": " Can you all see the nuclei touching the top of the apical membrane? And see the prominent nuclei. And see the nuclei are running in different directions. This nuclei is running in this direction, whereas this nuclei is running in this direction. This nuclei is running in this direction. So there is loss of cellular polarity. Okay, so here also it is stratified, reaching up to the top, and it is showing loss of cellular polarity. And see the cribriform. And this is a micropapillary process. Since it's a high power, you are not able to appreciate it better. I will show it to you in the other pictures. But here",
"med_umls_ids": "[[{'entity': 'Loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'cellular polarity', 'concept_id': 'C0085304', 'confidence': 1.0}, {'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}], [{'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'stratified', 'concept_id': 'C0205363', 'confidence': 1.0}, {'entity': 'cribriform', 'concept_id': 'C1621425', 'confidence': 0.9999999403953552}, {'entity': 'micropapillary process', 'concept_id': 'C1290608', 'confidence': 0.763504683971405}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_197",
"caption_rating": "8"
},
{
"": "1007306",
"caption": "Presence of internal elastic lamina indicates artery, while its absence indicates vein.",
"image_path": "r7OA0Trj5hQ_image_13da7322-e4b8-4a3d-8db9-cba386461840.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " In high power, you can see very thick vessel wall with the narrowing of the lumen, whereas here, it is relatively preserved. So you want to know whether it is a vein or artery. Please believe me, this is a vein, and this is an artery. And that is proved by the elastic tissue strain. These are all pictures from Dr. Gonzalez's Twitter. And you can see here, there is no internal elastic lamina, whereas here, there is an internal elastic lamina. So this is a branch of mesenteric artery, whereas this is a branch of mesenteric vein. And there is a condition called as idiopathic myointimal hyperplasia of the mesenteric vein. I don't know how many of you have heard this company. There's a",
"corrected_text": " In high power, you can see very thick vessel wall with the narrowing of the lumen, whereas here, it is relatively preserved. So you want to know whether it is a vein or artery. Please believe me, this is a vein, and this is an artery. And that is proved by the elastic tissue strain. These are all pictures from Dr. Gonzalez's Twitter. And you can see here, there is no internal elastic lamina, whereas here, there is an internal elastic lamina. So this is a branch of mesenteric artery, whereas this is a branch of mesenteric vein. And there is a condition called as idiopathic myointimal hyperplasia of mesenteric vein of the mesenteric vein. I don't know how many of you have heard this company. There's a",
"med_umls_ids": "[[{'entity': 'Thick vessel wall', 'concept_id': 'C1180033', 'confidence': 0.6420797109603882}, {'entity': 'lumen', 'concept_id': 'C0524461', 'confidence': 0.9999998807907104}, {'entity': 'power', 'concept_id': 'C0032863', 'confidence': 1.0}], [{'entity': 'Identification', 'concept_id': 'C0020792', 'confidence': 1.0}, {'entity': 'vein', 'concept_id': 'C0042449', 'confidence': 1.0}, {'entity': 'artery', 'concept_id': 'C0003842', 'confidence': 1.0}, {'entity': 'elastic tissue', 'concept_id': 'C0013762', 'confidence': 1.0}, {'entity': 'strain', 'concept_id': 'C0080194', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'internal elastic lamina', 'concept_id': 'C1180561', 'confidence': 1.0}, {'entity': 'artery', 'concept_id': 'C0003842', 'confidence': 1.0}, {'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'vein', 'concept_id': 'C0042449', 'confidence': 1.0}], [{'entity': 'Branches', 'concept_id': 'C1182977', 'confidence': 0.7288598418235779}, {'entity': 'mesenteric artery', 'concept_id': 'C0025465', 'confidence': 1.0}, {'entity': 'vein', 'concept_id': 'C0042449', 'confidence': 1.0}, {'entity': 'examples', 'concept_id': 'C1707959', 'confidence': 0.8639216423034668}], [{'entity': 'Idiopathic myointimal hyperplasia', 'concept_id': 'C0333978', 'confidence': 0.8139097094535828}, {'entity': 'mesenteric vein', 'concept_id': 'C0025473', 'confidence': 1.0}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_198",
"caption_rating": "7"
},
{
"": "1008545",
"caption": "Hemosiderin accumulates in mononuclear tumor cells around the periphery, referred to as ladybug or ladybird cells.",
"image_path": "j_rG5XPImFQ_image_ed964c45-9360-49f2-9c3d-5c51a6c87885.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Hematopathology', 'Breast pathology']",
"roi_text": "['ladybug or ladybird cells', 'CSF1R gene', 'tenosynovial giant cell tumor', 'giant cell tumor of soft tissue', 'peripheral ossification']",
"noisy_text": " Often, the hemosiderin likes to accumulate in mononuclear tumor cells around the periphery. These are referred to as ladybug or ladybird cells. So far, I've only talked about localized tenosynovial giant cell tumor. However, there is also a diffuse type. This type commonly arises in the larger joints and carries a risk of significant morbidity, since negative margins can be difficult to obtain. Both the localized and diffuse types of tenosynovial giant cell tumor have balanced translocations involving the chromosomal region of 1p13, which includes the CSF1 gene. Overexpression of CSF1 by tumor cells is what is thought to cause the recruitment of osteoclasts like giant cells. There are also giant cell tumors arising in the soft tissue and bone, and I'm going to talk a little bit about those. Giant cell tumor of soft tissue arises in the superficial soft tissues, most commonly in the arm, thigh, and calf. They may also have a rim of peripheral ossification, so myocytosis ossificans, which I've talked about in a previous video, may enter the differential based on the imaging findings. These lesions do not have any characteristic molecular alterations. Giant cell",
"corrected_text": " Often, the hemosiderin likes to accumulate in mononuclear tumor cells around the periphery. These are referred to as ladybug or ladybird cells. So far, I've only talked about localized tenosynovial giant cell tumor. However, there is also a diffuse type. This type commonly arises in the larger joints and carries a risk of significant morbidity, since negative margins can be difficult to obtain. Both the localized and diffuse types of tenosynovial giant cell tumor have balanced translocations involving the CSF1R gene the chromosomal region of 1p13, which includes the CSF1 gene. Overexpression of CSF1 by tumor cells is what is thought to cause the recruitment of osteoclasts like giant cells. There are also giant cell tumors arising in the soft tissue and bone, and I'm going to talk a little bit about those. Giant cell tumor of soft tissue arises in the superficial soft tissues, most commonly in the arm, thigh, and calf. They may also have a rim of peripheral ossification, so myositis ossificans, which I've talked about in a previous video, may enter the differential based on the imaging findings. These lesions do not have any characteristic molecular alterations. Giant cell",
"med_umls_ids": "[[{'entity': 'Hemosiderin', 'concept_id': 'C0019113', 'confidence': 1.0}, {'entity': 'accumulates', 'concept_id': 'C4055506', 'confidence': 0.8533105254173279}, {'entity': 'mononuclear tumor cells', 'concept_id': 'C0806987', 'confidence': 0.8775115013122559}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'ladybug', 'concept_id': 'C0886269', 'confidence': 1.0}, {'entity': 'ladybird cells', 'concept_id': 'C0998434', 'confidence': 0.736539363861084}], [{'entity': 'localized', 'concept_id': 'C0392752', 'confidence': 1.0}, {'entity': 'diffuse', 'concept_id': 'C0205219', 'confidence': 1.0}, {'entity': 'tenosynovial giant cell tumor', 'concept_id': 'C1318543', 'confidence': 1.0}, {'entity': 'balanced', 'concept_id': 'C0205415', 'confidence': 1.0}, {'entity': 'translocations', 'concept_id': 'C0040715', 'confidence': 1.0}, {'entity': 'CSF1R gene', 'concept_id': 'C0879468', 'confidence': 1.0}], [{'entity': 'Giant cell tumor', 'concept_id': 'C0017525', 'confidence': 1.0}, {'entity': 'soft tissue', 'concept_id': 'C0225317', 'confidence': 0.9999999403953552}, {'entity': 'superficial', 'concept_id': 'C0205124', 'confidence': 1.0}, {'entity': 'soft tissues', 'concept_id': 'C0225317', 'confidence': 1.0}, {'entity': 'arm', 'concept_id': 'C0003798', 'confidence': 1.0}, {'entity': 'thigh', 'concept_id': 'C0039866', 'confidence': 1.0}, {'entity': 'calf', 'concept_id': 'C0230445', 'confidence': 1.0}, {'entity': 'rim', 'concept_id': 'C1308727', 'confidence': 1.0}, {'entity': 'peripheral ossification', 'concept_id': 'C0029433', 'confidence': 0.7698169350624084}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_199",
"caption_rating": "9"
},
{
"": "1008382",
"caption": "It is important to document the invasive component and the possible origin of the carcinoma.",
"image_path": "iklRyY1nBIE_image_d8f95d8f-96e0-4889-9a62-34c9265898a1.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['Invasive urethral carcinoma involving the prostate.', 'Possible origin of the carcinoma from the prosthetic urethra or bladder.']",
"noisy_text": " So this is an invasive component. So it's very important to document that. So you can't just say urethral carcinoma involving the prostate, you need to say there's a lot of colonization. But you need to also make it clear that there's an invasive component. Now the next question some of you may ask me is, OK, so where is this coming from? Is this coming from the prosthetic urethra? Is this coming from the bladder? And sometimes you can't tell. And it's very important, to be honest, in your report, especially if it's a small biopsy or a top sample, where you can't see urethral carcinoma inside the component, that it could be arising from the prosthetic urethra. But you cannot exclude the possibility of this arising from the bladder. It's very important to document that. Even if you see an incisor component, that does not exclude that it's coming from the bladder. Because sometimes you can have secondary tumors colonize the surface and mimic a primary lesion. So that's an important point to keep in mind. So that was an interesting case I thought I'd share. We're going to move on to case nine shortly. Case nine is a 45-year-old gentleman that presented with a positive digital rectal examination and elevated PSA levels. So remember that age is just 45. I also shared this with you. I think",
"corrected_text": " So this is an invasive component. So it's very important to document that. So you can't just say urethral carcinoma involving the prostate, you need to say there's a lot of colonization. But you need to also make it clear that there's an invasive component. Now the next question some of you may ask me is, OK, so where is this coming from? Is this coming from the prosthetic urethra? Is this coming from the bladder? And sometimes you can't tell. And it's very important, to be honest, in your report, especially if it's a small biopsy or a top sample, where you can't see urethral carcinoma inside the component, that it could be arising from the prosthetic urethra. But you cannot exclude the possibility of this arising from the bladder. It's very important to document that. Even if you see an incisor component, that does not exclude that it's coming from the bladder. Because sometimes you can have secondary tumors colonize the surface and mimic a primary lesion. So that's an important point to keep in mind. So that was an interesting case I thought I'd share. We're going to move on to case nine shortly. Case nine is a 45-year-old gentleman that presented with a positive digital rectal examination and elevated PSA levels. So remember that age is just 45. I also shared this with you. I think",
"med_umls_ids": "[[{'entity': 'Invasive', 'concept_id': 'C0205281', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'colonization', 'concept_id': 'C4289767', 'confidence': 1.0}], [{'entity': 'document', 'concept_id': 'C1301746', 'confidence': 1.0}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}, {'entity': 'component', 'concept_id': 'C0449432', 'confidence': 1.0}, {'entity': 'origin', 'concept_id': 'C0079946', 'confidence': 1.0}, {'entity': 'carcinoma', 'concept_id': 'C0007097', 'confidence': 1.0}], [{'entity': 'Secondary tumors', 'concept_id': 'C0027627', 'confidence': 0.9999999403953552}, {'entity': 'colonize', 'concept_id': 'C3829074', 'confidence': 0.6422675251960754}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'primary', 'concept_id': 'C0205225', 'confidence': 1.0}, {'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_200",
"caption_rating": "7"
},
{
"": "1005416",
"caption": "Invasive cancer colonizing a previously benign gland.",
"image_path": "iklRyY1nBIE_image_1d95b4a8-2919-46d4-9c9c-bb6bb361ce5c.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['Invasive cancer entering and colonizing the gland.', 'Solid cribriform pattern.', 'Tumor cells with prominent nucleoli.']",
"noisy_text": " when you see a foci like this, where the invasive cancer looks like it's actually invading, colonizing a previously benign gland. In some areas, you can actually see it's basically caught in the act. You can see the invasive cancer actually entering the gland and colonizing it. Again, this is like a solid cribriform pattern. This would be way too much for high-grade pain. For those who are wondering, how do you distinguish between high-grade pain and introductal carcinoma of the prostate, I'll show you an example of high-grade pain. Shortly, they are completely different. When you look at them back to back, you see that they are completely different processes. This is a very, very bad-looking process here. You can see lots of tumor cells, large tumor cells, prominent nucleoli. And they are packing over 70% of this is actually composed of tumor cells. So it subtly meets the criteria for introductal carcinoma of the prostate. And again, as I said earlier, you can see the adjacent cancer, the adjacent invasive cancer is very high-grade. So when we talk about introductal carcinoma of the",
"corrected_text": " when you see a foci like this, where the invasive cancer looks like it's actually invading, colonizing a previously benign gland. In some areas, you can actually see it's basically caught in the act. You can see the invasive cancer actually entering the gland and colonizing it. Again, this is like a solid cribriform pattern. This would be way too much for high-grade pain. For those who are wondering, how do you distinguish between high-grade pain and intr ductal carcinoma of the prostate, I'll show you an example of high-grade pain. Shortly, they are completely different. When you look at them back to back, you see that they are completely different processes. This is a very, very bad-looking process here. You can see lots of tumor cells, large tumor cells, prominent nucleoli. And they are packing over 70% of this is actually composed of tumor cells. So it subtly meets the criteria for intr ductal carcinoma of the prostate. And again, as I said earlier, you can see the adjacent cancer, the adjacent invasive cancer is very high-grade. So when we talk about intr ductal carcinoma of the",
"med_umls_ids": "[[{'entity': 'Invasive cancer', 'concept_id': 'C0677898', 'confidence': 1.0}, {'entity': 'colonizing', 'concept_id': 'C1300196', 'confidence': 0.61208176612854}, {'entity': 'benign gland', 'concept_id': 'C0205183', 'confidence': 0.7986565828323364}], [{'entity': 'Solid cribriform pattern', 'concept_id': 'C1333163', 'confidence': 0.8988972902297974}, {'entity': 'invasive cancer', 'concept_id': 'C0677898', 'confidence': 1.0}], [{'entity': 'high-grade', 'concept_id': 'C1512433', 'confidence': 0.9347730875015259}, {'entity': 'PIN', 'concept_id': 'C0175718', 'confidence': 1.0}, {'entity': 'intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}], [{'entity': 'High-grade', 'concept_id': 'C1512433', 'confidence': 0.9347730875015259}, {'entity': 'PIN', 'concept_id': 'C0175718', 'confidence': 1.0}, {'entity': 'intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'processes', 'concept_id': 'C0230625', 'confidence': 0.8310701847076416}], [{'entity': 'Intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'bad-looking process', 'concept_id': 'C3158129', 'confidence': 0.5375546813011169}, {'entity': 'lots', 'concept_id': 'C0302148', 'confidence': 0.7982692718505859}, {'entity': 'tumor cells', 'concept_id': 'C0431085', 'confidence': 1.0}, {'entity': 'prominent', 'concept_id': 'C0205402', 'confidence': 0.9999999403953552}, {'entity': 'nucleoli', 'concept_id': 'C0007609', 'confidence': 0.8710004091262817}], [{'entity': 'Adjacent', 'concept_id': 'C0205117', 'confidence': 1.0}, {'entity': 'invasive cancer', 'concept_id': 'C0677898', 'confidence': 1.0}, {'entity': 'high-grade', 'concept_id': 'C1512433', 'confidence': 0.9347730875015259}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_201",
"caption_rating": "8"
},
{
"": "1009002",
"caption": "This was an example of a biopsy from a patient with clinically documented pityriasis lichenoides chronica.",
"image_path": "8S4LeiO6Bbk_image_8babc89a-e6f4-49c9-a23a-79c16fb030c5.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Infiltrate within the dermis composed entirely of lymphocytes.', 'Few extravasated erythrocytes in some areas.', 'Fragmented biopsy specimen with bluish stain.', 'Infiltrate within the dermis composed entirely of lymphocytes.', 'Few extravasated erythrocytes in some areas.']",
"noisy_text": " and if we look at the infiltrate within the dermis, we can see that it's composed entirely of lymphocytes. In some areas, there were a few extravasated erythrocytes, a few of which were carried up into the overlying epidermis. This constellation of findings is most suggestive of pittoriasis liganoides. Clinically, this patient had PLC, or pittoriasis liganoides chronica. I tend to view pittoriasis liganoides as running along a spectrum. A lot of times, we'll refer to the entire spectrum as Leuka Habermann disease, with pittoriasis liganoides chronica being on the one end of the spectrum, and pleva being on the other end of the spectrum, PLC being characterized by more scaly macules or scaly papules, and pleva being characterized by more crusted and eroded papulonecrotic type lesions. But the histology of the two conditions is actually quite similar. It's a matter of degree. With pleva, you're more likely the acute form of the condition to see more spongiosis, ballooning, necrosis, a denser infiltrate, more necrotics along the DEJ, pericaratosis containing neutrophils. With PLC, similar findings, just a little more blunt. The inflammatory infiltrate may be present around the superficial plexus only. One usually can see some pericaratosis, but there aren't as many necrotic keratinocytes along the DEJ, and a lot of times, the alterations within the epidermis are more subtle. But this was an example of biopsy from a patient with clinically documented pittoriasis like in wades clonica. Moving on to slide number 10. This was, I thought, a really cool case. This was a fragmented biopsy specimen, and you can see that the stain is quite bluish. I can't",
"corrected_text": " and if we look at the infiltrate within the dermis, we can see that it's composed entirely of lymphocytes. In some areas, there were a few extravasated erythrocytes, a few of which were carried up into the overlying epidermis. This constellation of findings is most suggestive of pityriasis lichenoides. Clinically, this patient had PLC, or pityriasis lichenoides chronica. I tend to view pityriasis lichenoides as running along a spectrum. A lot of times, we'refer to the entire spectrum as Leuka Habermann disease, with pityriasis lichenoides chronica being on the one end of the spectrum, and pleva being on the other end of the spectrum, PLC being characterized by more scaly macules or scaly papules, and pleva being characterized by more crusted and eroded papulonecrotic type lesions. But the histology of the two conditions is actually quite similar. It's a matter of degree. With pleva, you're more likely the acute form of the condition to see more spongiosis, ballooning, necrosis, a denser infiltrate, more necrotic along the DEJ, parakeratosis containing neutrophils. With PLC, similar findings, just a little more blunt. The inflammatory infiltrate may be present around the superficial plexus only. One usually can see some parakeratosis, but there aren't as many necrotic keratinocytes along the DEJ, and a lot of times, the alterations within the epidermis are more subtle. But this was an example of biopsy from a patient with clinically documented pittoriasis like in chronica. Moving on to slide number 10. This was, I thought, a really cool case. This was a fragmented biopsy specimen, and you can see that the stain is quite bluish. I can't",
"med_umls_ids": "[[{'entity': 'dermal infiltrate', 'concept_id': 'C0332448', 'confidence': 0.8524853587150574}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'extravasated', 'concept_id': 'C0015376', 'confidence': 0.868863582611084}, {'entity': 'erythrocytes', 'concept_id': 'C0014772', 'confidence': 1.0}, {'entity': 'areas', 'concept_id': 'C0205146', 'confidence': 1.0}, {'entity': 'pityriasis', 'concept_id': 'C0032024', 'confidence': 0.9999998807907104}, {'entity': 'lichenoides', 'concept_id': 'C0443248', 'confidence': 0.8475416302680969}], [{'entity': 'Pityriasis lichenoides', 'concept_id': 'C0162853', 'confidence': 1.0}, {'entity': 'running', 'concept_id': 'C0035953', 'confidence': 1.0}, {'entity': 'spectrum', 'concept_id': 'C1883073', 'confidence': 1.0}, {'entity': 'pityriasis lichenoides chronica', 'concept_id': 'C0162851', 'confidence': 1.0}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'scaly macules', 'concept_id': 'C0332573', 'confidence': 0.7616965174674988}, {'entity': 'papules', 'concept_id': 'C0332563', 'confidence': 0.9999999403953552}], [{'entity': 'histology', 'concept_id': 'C0019638', 'confidence': 1.0}, {'entity': 'pityriasis lichenoides', 'concept_id': 'C0162853', 'confidence': 1.0}, {'entity': 'pleva', 'concept_id': 'C0162852', 'confidence': 1.0}, {'entity': 'pleva', 'concept_id': 'C0162852', 'confidence': 1.0}, {'entity': 'acute', 'concept_id': 'C0205178', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'spongiosis', 'concept_id': 'C0702120', 'confidence': 1.0}, {'entity': 'ballooning', 'concept_id': 'C0004704', 'confidence': 1.0}, {'entity': 'necrosis', 'concept_id': 'C0027540', 'confidence': 1.0}], [{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'clinically documented', 'concept_id': 'C1828480', 'confidence': 0.814785361289978}, {'entity': 'pityriasis lichenoides chronica', 'concept_id': 'C0162851', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_202",
"caption_rating": "8"
},
{
"": "1008838",
"caption": "The diagnosis is a desmoplastic tricholemmomaphthelioma, which has a different morphology and stroma than a MAC.",
"image_path": "LlPaENuqzVQ_image_a5e8aca7-3eca-4702-9f56-0268c095f78a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['calcification', 'cleft between the stroma and the epithelium', 'desmoplastic tricholemmomaphthelioma', 'calcification', 'perineural invasion', 'cleft between the stroma and the epithelium']",
"noisy_text": " There may be some little small duct-like structures at the top of the calcification. This is a desmoplastic trichophthelioma. It's different than a MAC. So it's got a different morphology. It's got the calcification and different stroma. These do not get neurotropic involvement. So, and you know, this is a definitive diagnosis here also. We don't need to stain this or anything. We would diagnose this as a desmoplastic MAC or a microcystic or a desmoplastic tricho and then just move on to the next case. It's different than MAC. It's different than basal cell. It doesn't have the clest between the stroma and the epithelium here. Okay, so",
"corrected_text": " There may be some little small duct-like structures at the top of the calcification. This is a desmoplastic trichoepithelioma. It's different than a MAC. So it's got a different morphology. It's got the calcification and different stroma. These do not get neurotropic involvement. So, and you know, this is a definitive diagnosis here also. We don't need to stain this or anything. We would diagnose this as a desmoplastic MAC or a microcystic or a desmoplastic tricho and then just move on to the next case. It's different than MAC. It's different than basal cell. It doesn't have the cleft between the stroma and the epithelium here. Okay, so",
"med_umls_ids": "[[{'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'desmoplastic tricholemmomaphthelioma', 'concept_id': 'C1275206', 'confidence': 0.8335589170455933}, {'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}, {'entity': 'stroma', 'concept_id': 'C0927195', 'confidence': 1.0}, {'entity': 'MAC', 'concept_id': 'C0009545', 'confidence': 0.9999999403953552}], [{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'perineural invasion', 'concept_id': 'C1317608', 'confidence': 1.0}], [{'entity': 'duct-like structures', 'concept_id': 'C1880423', 'confidence': 0.9012507796287537}, {'entity': 'calcification', 'concept_id': 'C0006660', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_203",
"caption_rating": "7"
},
{
"": "1005941",
"caption": "Presence of a vascular neoplasm with dilated endothelial line spaces and a biphasic pattern.",
"image_path": "8S4LeiO6Bbk_image_5e4d9616-68f1-4771-aa97-50575d8a7114.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['papillary projections', 'extravasated erythrocytes', 'dilated vessels', 'enlarged endothelial cells', 'collagen bundles', 'pre-existing vascular spaces', 'papillary projections', 'extravasated erythrocytes', 'dilated vessels', 'enlarged endothelial cells', 'collagen bundles', 'pre-existing vascular spaces', 'papillary projections', 'extravasated erythrocytes', 'dilated vessels', 'enlarged endothelial cells', 'collagen bundles', 'pre-existing vascular spaces']",
"noisy_text": " into the limina. If you look around, you can see these papillary projections. There are a few extravasated erythrocytes present within the stroma. So clearly, we've got this vascular neoplasma here with these dilated endothelial line spaces, but it's got kind of a bifasic pattern. Centrally, we've got these dilated vessels, but peripheral and beneath that zone, the vessels are somewhat more compressed. They're still lined by some of the plump endothelial cells. And in these various where the vessels are compressed, they kind of appear to dissect between collagen bundles. We even have a little bit of a promontory sign here where we've got these vessels surrounding pre-existing vascular spaces. But unlike the neovascular spaces that we see in Kaposi's sarcoma, the endothelial cells here are a little more plump, and we don't have plasma cells within the infiltrate. And plasma cells within the infiltrate can be very useful in discriminating between this condition and Kaposi's sarcoma. In this particular case, also the HHV8 stain was a negative, which",
"corrected_text": " into the limina. If you look around, you can see these papillary projections. There are a few extravasated erythrocytes present within the stroma. So clearly, we've got this vascular neoplasm here with these dilated endothelial line spaces, but it's got kind of a biphasic pattern. Centrally, we've got these dilated vessels, but peripheral and beneath that zone, the vessels are somewhat more compressed. They're still lined by some of the enlarged endothelial cells. And in these various where the vessels are compressed, they kind of appear to dissect between collagen bundles. We even have a little bit of a promontory sign here where we've got these vessels surrounding pre-existing vascular spaces. But unlike the neovascularization that we see in Kaposi's sarcoma, the endothelial cells here are a little more plump, and we don't have plasma cells within the infiltrate. And plasma cells within the infiltrate can be very useful in discriminating between this condition and Kaposi's sarcoma. In this particular case, also the HHV8 stain was a negative, which",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'vascular neoplasm', 'concept_id': 'C0027668', 'confidence': 1.0}, {'entity': 'dilated endothelial line spaces', 'concept_id': 'C0014257', 'confidence': 0.6450937390327454}, {'entity': 'biphasic pattern', 'concept_id': 'C1332555', 'confidence': 1.0}], [{'entity': 'Vessels', 'concept_id': 'C0005847', 'confidence': 1.0}, {'entity': 'peripheral', 'concept_id': 'C0205100', 'confidence': 1.0}, {'entity': 'central zone', 'concept_id': 'C0458698', 'confidence': 1.0}], [{'entity': 'Endothelial cells', 'concept_id': 'C0225336', 'confidence': 1.0}, {'entity': 'enlarged', 'concept_id': 'C0442800', 'confidence': 1.0}, {'entity': 'plump', 'concept_id': 'C1836543', 'confidence': 0.7694027423858643}], [{'entity': 'Absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'differentiate', 'concept_id': 'C0205615', 'confidence': 0.9999998807907104}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'Kaposi sarcoma', 'concept_id': 'C0036220', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "758.0",
"width": "1920.0",
"id": "test_204",
"caption_rating": "9"
},
{
"": "1005186",
"caption": "Only about 30% of granular cell tumors show positive staining for PAS, making it an ineffective stain for diagnosis.",
"image_path": "jSW3u54ZEfk_image_a3acdd1d-26c2-42d8-946f-de67860e39b1.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Head and Neck', 'Soft tissue']",
"roi_text": "['Granular cell tumor in the skin', 'Granular nature of cytoplasm', 'Streaks of dark pink staining tissue (bands of fibrous)']",
"noisy_text": " This is not really surprising as only approximately 30% of granular cell tumours do show positive staining for PAS and this really illustrates the fact that PAS is not a particularly useful stain for granular cell tumours given that the majority fail to stain for it. This is a granular cell tumour arising in the skin. At a higher magnification the granular nature of the cytoplasm is revealed and between the granular cells there are streaks of dark pink staining tissue and these are bands of fibrous tissue typical",
"corrected_text": " This is not really surprising as only approximately 30% of granular cell tumours do show positive staining for PAS and this really illustrates the fact that PAS is not a particularly useful stain for granular cell tumours given that the majority fail to stain for it. This is a granular cell tumour arising in the skin. At a higher magnification the granular nature of the cytoplasm is revealed and between the granular cells there are streaks of dark pink staining tissue and these are bands of fibrous tissue typical",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'granular', 'concept_id': 'C0205248', 'confidence': 1.0}, {'entity': 'cell tumor', 'concept_id': 'C0431085', 'confidence': 0.9999998807907104}, {'entity': 'skin', 'concept_id': 'C0444099', 'confidence': 1.0}], [{'entity': 'granular', 'concept_id': 'C0205248', 'confidence': 1.0}, {'entity': 'cell tumors', 'concept_id': 'C1956421', 'confidence': 0.8782677054405212}, {'entity': 'positive staining', 'concept_id': 'C1446409', 'confidence': 0.7295212745666504}, {'entity': 'PAS', 'concept_id': 'C0030125', 'confidence': 1.0}, {'entity': 'ineffective', 'concept_id': 'C3242229', 'confidence': 1.0}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_205",
"caption_rating": "8"
},
{
"": "1009102",
"caption": "Histopathological description of an epithelial tumor with interconnected cords and strands.",
"image_path": "8S4LeiO6Bbk_image_1e8d3c8f-6507-4fdb-b5cf-6edd5afdfe9f.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['lymphocytes', 'epithelial tumor', 'cytoplasm', 'vesicular chromatin pattern', 'lymphocytes', 'duct formation', 'cytoplasm']",
"noisy_text": " If we move to higher power, we can see that we're dealing with an epithelial rather than a mosaicable tumor. We've got interconnected cords and strands. We have somewhat of a ribiform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of the cells are round to oval. They're fairly large. These cells have some faint eosinophilic to pale gray cytoplasm, although this cytoplasm is kind of difficult to see. Some of these cells have an evenly dispersed or vesicular chromatin pattern, and other nuclei are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and",
"corrected_text": " If we move to higher power, we can see that we're dealing with an epithelial rather than a mesenchymal tumor. We've got interconnected cords and strands. We have somewhat of a cribriform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of the cells are round to oval. They're fairly large. These cells have some faint eosinophilic to pale gray cytoplasm, although this cytoplasm is kind of difficult to see. Some of these cells have an evenly dispersed or vesicular chromatin pattern, and other nuclei are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'epithelial tumor', 'concept_id': 'C1368683', 'confidence': 0.9999999403953552}, {'entity': 'cords', 'concept_id': 'C0034869', 'confidence': 0.801885187625885}, {'entity': 'strands', 'concept_id': 'C0600383', 'confidence': 0.800572395324707}], [{'entity': 'Cribriform pattern', 'concept_id': 'C1333163', 'confidence': 1.0}, {'entity': 'loose', 'concept_id': 'C0205407', 'confidence': 1.0}, {'entity': 'edematous', 'concept_id': 'C0013604', 'confidence': 1.0}, {'entity': 'vascular stroma', 'concept_id': 'C0005847', 'confidence': 0.8046398758888245}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'cell types', 'concept_id': 'C0007634', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'eosinophilic', 'concept_id': 'C0333930', 'confidence': 1.0}, {'entity': 'pale', 'concept_id': 'C0030232', 'confidence': 1.0}, {'entity': 'gray cytoplasm', 'concept_id': 'C0010834', 'confidence': 0.8177905678749084}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'duct', 'concept_id': 'C0687028', 'confidence': 1.0}, {'entity': 'formation', 'concept_id': 'C0220781', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_206",
"caption_rating": "9"
},
{
"": "1008588",
"caption": "Description of fibro and myxoid components of tumors, with a predominantly fibrous pink component and a lesser myxoid bluish component.",
"image_path": "QDb68_G1HR4_image_cc9a027d-46a5-4375-ab50-73870409d944.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['fibro', 'myxoid', 'spindle cell thing']",
"noisy_text": " So the fibro is the pink part, the myxoid is the bluish pale part and these tumors usually not always but usually have a predominantly fibrous pink component and a lesser myxoid bluish component so it looks more pink. The way I also remember it is some of the original tumors that Dr. Evans described were misdiagnosed originally as either fibroma which is a good example of why it's dangerous to call something just fibroma not otherwise specified just because you see a spindle cell thing that looks fibroblastic and benign and you don't have a good name for it. That doesn't mean it's a fibroma, that's the way that tumors like this get missed. And the other",
"corrected_text": " So the fibro is the pink part, the myxoid is the bluish pale part and these tumors usually not always but usually have a predominantly fibrous pink component and a lesser myxoid bluish component so it looks more pink. The way I also remember it is some of the original tumors that Dr. Evans described were misdiagnosed originally as either fibroma which is a good example of why it's dangerous to call something just fibroma not otherwise specified just because you see a spindle cell thing that looks fibroblastic and benign and you don't have a good name for it. That doesn't mean it's a fibroma, that's the way that tumors like this get missed. And the other",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'fibro', 'concept_id': 'C0016053', 'confidence': 0.9999999403953552}, {'entity': 'myxoid components', 'concept_id': 'C0449432', 'confidence': 0.6883944869041443}, {'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'fibrous pink', 'concept_id': 'C0439709', 'confidence': 0.7378140091896057}, {'entity': 'lesser', 'concept_id': 'C0547044', 'confidence': 1.0}], [{'entity': 'Misdiagnosis', 'concept_id': 'C0679838', 'confidence': 1.0}, {'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'fibroma', 'concept_id': 'C0016045', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_207",
"caption_rating": "8"
},
{
"": "1007868",
"caption": "P63 and hemoglobin cytokeratin highlight the basal cells.",
"image_path": "iklRyY1nBIE_image_869c5468-faf3-4487-a43c-bbb6750545d5.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['The focus of interest', 'The glands with positive basal cell markers', 'The focus of interest', 'The glands with positive basal cell markers']",
"noisy_text": " And this is the focus of interest right here. So again, for the medical students who are in the audience, the pink cocktail is a combination of hemoglobin cytokeratin, P63, and P504S, also known as Amacar. P63 and hemoglobin cytokeratin highlight the basal cells. P63 is a nuclear stain, and the hemoglobin cytokeratin is more of a wispy kind of membrane on cytoplasmic stain. So as you can see, it's always important to look at the internal control. Any time you get a stain, you want to look at the glands you know are benign. You want to make sure the stain worked very well, because if the stain didn't work very well, that can get you in trouble when you're looking at the focus of interest. But if we come back to this particular case here, we can see that the stains worked very well. The basal cell markers are positive in the glands. We are comfortable or benign. The problem is when we come to this area we were looking at earlier, you can see that",
"corrected_text": " And this is the focus of interest right here. So again, for the medical students who are in the audience, the pink cocktail is a combination of hemoglobin cytokeratin, P63, and P504S, also known as Amacar. P63 and hemoglobin cytokeratin highlight the basal cells. P63 is a nuclear stain, and the hemoglobin cytokeratin is more of a wispy kind of membrane on cytoplasmic stain. So as you can see, it's always important to look at the internal control. Any time you get a stain, you want to look at the glands you know are benign. You want to make sure the stain worked very well, because if the stain didn't work very well, that can get you in trouble when you're looking at the focus of interest. But if we come back to this particular case here, we can see that the stains worked very well. The basal cell markers are positive in the glands. We are comfortable or benign. The problem is when we come to this area we were looking at earlier, you can see that",
"med_umls_ids": "[[{'entity': 'pink cocktail', 'concept_id': 'C0678420', 'confidence': 0.8575658798217773}, {'entity': 'combination', 'concept_id': 'C0205195', 'confidence': 1.0}, {'entity': 'hemoglobin cytokeratin', 'concept_id': 'C0010803', 'confidence': 0.7460406422615051}, {'entity': 'P63', 'concept_id': 'C1422009', 'confidence': 1.0}, {'entity': 'P504S', 'concept_id': 'C1172764', 'confidence': 0.9999999403953552}, {'entity': 'Amacar', 'concept_id': 'C3469830', 'confidence': 0.649845540523529}], [{'entity': 'P63', 'concept_id': 'C1422009', 'confidence': 1.0}, {'entity': 'hemoglobin cytokeratin', 'concept_id': 'C0010803', 'confidence': 0.7460406422615051}, {'entity': 'basal cells', 'concept_id': 'C0596155', 'confidence': 1.0}], [{'entity': 'internal control', 'concept_id': 'C0597937', 'confidence': 0.9999999403953552}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}], [{'entity': 'basal cell', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'markers', 'concept_id': 'C0181734', 'confidence': 0.890313982963562}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'benign', 'concept_id': 'C0205183', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_208",
"caption_rating": "7"
},
{
"": "1008300",
"caption": "The lesion is likely a sebaceoma, which can be mistaken for basal cell carcinoma with sebaceous differentiation.",
"image_path": "udoW6VSqsm4_image_d54daff7-58ee-4355-9487-59b5c47f6572.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['sebaceoma', 'basal cell carcinoma', 'sebaceous differentiation']",
"noisy_text": " I think we've called it sebaceous epithelium, but again I'm not a big fan of that term. And these look usually like this. They're usually small, round, skin-colored leaves. They kind of look like sebaceous epithelium. They usually come in as real-life basins, so nobody diagnoses these clinically correctly. So these are items in the differential diagnosis. Basal cell with sebaceous differentiation, if you're going to make that diagnosis, it generally needs to look like a basal cell with nice clefting and put the palisade in there and all that, and then have foci where there's obvious sebaceous differentiation. You'll see that on occasion. But I would probably call this sebaceoma, without thinking it's sort of synonymous with sebaceous epithelium. Now, is there any condition you have to worry about with these? With any",
"corrected_text": " I think we've called it sebaceous epithelium, but again I'm not a big fan of that term. And these look usually like this. They're usually small, round, skin-colored leaves. They kind of look like sebaceous epithelium. They usually come in as real-life basins, so nobody diagnoses these clinically correctly. So these are items in the differential diagnosis. Basal cell with sebaceous differentiation, if you're going to make that diagnosis, it generally needs to look like a basal cell with nice clefting and put the palisade in there and all that, and then have foci where there's obvious sebaceous differentiation. You'll see that on occasion. But I would probably call this sebaceoma, without thinking it's sort of synonymous with sebaceous epithelium. Now, is there any condition you have to worry about with these? With any",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'sebaceoma', 'concept_id': 'C1275210', 'confidence': 1.0}, {'entity': 'basal cell carcinoma', 'concept_id': 'C0007117', 'confidence': 1.0}, {'entity': 'sebaceous differentiation', 'concept_id': 'C1882988', 'confidence': 1.0}], [{'entity': 'Sebaceomas', 'concept_id': 'C1275210', 'confidence': 0.8855459690093994}, {'entity': 'small', 'concept_id': 'C0700321', 'confidence': 0.9999998807907104}, {'entity': 'round', 'concept_id': 'C0332490', 'confidence': 1.0}, {'entity': 'skin-colored', 'concept_id': 'C4476819', 'confidence': 0.8005288243293762}], [{'entity': 'Basal cell carcinoma', 'concept_id': 'C0007117', 'confidence': 1.0}, {'entity': 'sebaceous differentiation', 'concept_id': 'C1882988', 'confidence': 1.0}, {'entity': 'clefting', 'concept_id': 'C4021813', 'confidence': 0.8906428217887878}, {'entity': 'palisading', 'concept_id': 'C1622240', 'confidence': 0.8684062361717224}, {'entity': 'sebaceous differentiation', 'concept_id': 'C1882988', 'confidence': 1.0}], [{'entity': 'conditions', 'concept_id': 'C0012634', 'confidence': 0.8556983470916748}, {'entity': 'concern', 'concept_id': 'C2699424', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_209",
"caption_rating": "8"
},
{
"": "1008223",
"caption": "Heterochromatin and nucleoplasm can be identified in plasma cells.",
"image_path": "Wiyo6taYRF4_image_f2fd3cc2-b10f-44d2-aa3a-167b1cde6571.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Hematopathology', 'Neuropathology', 'Cytopathology']",
"roi_text": "['neuroendocrine carcinoma', 'hyperchromatic nuclei', 'vesicular nuclei', 'nucleoli', 'salt and pepper chromatin', 'nucleoli', 'salt and pepper chromatin']",
"noisy_text": " and pepper like copper chromatin, that means you're telling that this is most likely a neuroendocrine kind of a carcinoma. So those are the different types of nuclei that we have seen. Again, to go back at the reference, we are going to look at the plasma cell. In the plasma cell, we can easily identify the hetero and the vesicular areas, that is heterochromatin and nucleomatin. If the cell is entirely composed of heterochromatin, it will be very dark-staining. And this is called as hyperchromatic nuclei. If it is composed of lightly-stained nuclei, lightly-stained areas, then it is called vesicular nuclei. A vesicular nuclei is usually accompanied by a nucleoli. And if you have very finely granular dark and light areas, then it is called as salt and pepper chromatin. And these are the defining features for a neuroendocrine tumor. Now, once we have understood the staining pattern of the",
"corrected_text": " and pepper like copper chromatin, that means you're telling that this is most likely a neuroendocrine kind of a carcinoma. So those are the different types of nuclei that we have seen. Again, to go back at the reference, we are going to look at the plasma cell. In the plasma cell, we can easily identify the hetero and the vesicular areas, that is heterochromatin and nucleoplasm. If the cell is entirely composed of heterochromatin, it will be very hyperchromatic. And this is called as hyperchromatic nuclei. If it is composed of lightly-stained areas, lightly-stained areas, then it is called vesicular nuclei. A vesicular nuclei is usually accompanied by a nucleoli. And if you have very finely granular dark and light areas, then it is called as salt and pepper chromatin. And these are the defining features for a neuroendocrine tumor. Now, once we have understood the staining pattern of the",
"med_umls_ids": "[[{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'pepper-like copper chromatin', 'concept_id': 'C0453397', 'confidence': 0.5605897903442383}, {'entity': 'neuroendocrine carcinoma', 'concept_id': 'C0206695', 'confidence': 1.0}], [{'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'observed', 'concept_id': 'C1441672', 'confidence': 1.0}, {'entity': 'hyperchromatic', 'concept_id': 'C0333911', 'confidence': 1.0}, {'entity': 'vesicular nuclei', 'concept_id': 'C2325471', 'confidence': 0.7651268839836121}], [{'entity': 'Heterochromatin', 'concept_id': 'C0019397', 'confidence': 1.0}, {'entity': 'nucleoplasm', 'concept_id': 'C0682537', 'confidence': 1.0}, {'entity': 'identified', 'concept_id': 'C0205396', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}], [{'entity': 'Vesicular nuclei', 'concept_id': 'C2325471', 'confidence': 0.7651268839836121}, {'entity': 'nucleoli', 'concept_id': 'C0007609', 'confidence': 0.8710004091262817}], [{'entity': 'Salt', 'concept_id': 'C0036140', 'confidence': 1.0}, {'entity': 'pepper chromatin', 'concept_id': 'C0008546', 'confidence': 0.7025638818740845}, {'entity': 'neuroendocrine tumor', 'concept_id': 'C0206754', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1152.0",
"id": "test_210",
"caption_rating": "7"
},
{
"": "1009125",
"caption": "Multilobulated growth and dense fibrosis are present in this tumor.",
"image_path": "j_rG5XPImFQ_image_80d9c191-1c69-4c48-b896-3b788cf951ee.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Hematopathology', 'Breast pathology']",
"roi_text": "['multilobulated growth', 'dense fibrosis', 'giant cells', 'multilobulated growth', 'dense fibrosis', 'giant cells']",
"noisy_text": " Mitotic activity can be relatively high, but this on its own should not be concerning for malignant transformation. In this case, you could see that the giant cells were not numerous, and there was minimal hemosiderin deposition. To give you a better sense of the morphologic spectrum of this tumor, I'm going to show a couple more examples. In this example, we still have multilobulated growth and dense fibrosis. However, even at low power, you can see that the giant cells are larger and more numerous than the previous example.",
"corrected_text": " Mitotic activity can be relatively high, but this on its own should not be concerning for malignant transformation. In this case, you could see that the giant cells were not numerous, and there was minimal hemosiderin deposition. To give you a better sense of the morphologic spectrum of this tumor, I'm going to show a couple more examples. In this example, we still have multilobulated growth and dense fibrosis. However, even at low power, you can see that the giant cells are larger and more numerous than the previous example.",
"med_umls_ids": "[[{'entity': 'Mitotic activity', 'concept_id': 'C1334779', 'confidence': 1.0}, {'entity': 'malignant transformation', 'concept_id': 'C0287850', 'confidence': 0.8324378132820129}], [{'entity': 'Giant cells', 'concept_id': 'C0017526', 'confidence': 1.0}, {'entity': 'hemosiderin', 'concept_id': 'C0019113', 'confidence': 1.0}, {'entity': 'deposition', 'concept_id': 'C0333562', 'confidence': 1.0}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}], [{'entity': 'Multilobulated', 'concept_id': 'C4538849', 'confidence': 0.8302288055419922}, {'entity': 'growth', 'concept_id': 'C0018270', 'confidence': 1.0}, {'entity': 'dense fibrosis', 'concept_id': 'C0016059', 'confidence': 0.8111783862113953}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}], [{'entity': 'Giant cells', 'concept_id': 'C0017526', 'confidence': 1.0}, {'entity': 'larger', 'concept_id': 'C0549177', 'confidence': 1.0}, {'entity': 'numerous', 'concept_id': 'C0439064', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_211",
"caption_rating": "8"
},
{
"": "1007005",
"caption": "The presence of branching vessels with dense sclerosis around those vessels is a pattern seen in solitary fibrous tumor.",
"image_path": "QDb68_G1HR4_image_9497eaf4-0e84-4dbb-a872-82f1436b44fb.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Collagenous areas', 'Branching vessels with dense sclerosis', 'Solitary fibrous tumor pattern']",
"noisy_text": " There's some nice collagenous areas and look it's got branching vessels with dense sclerosis around those vessels. That's a pattern you could see in solitary fibrous tumor. Solitary fibrous tumor will usually be CD34 positive. This tumor again low grade fibromyxoid sarcoma is usually negative. I know I'm repeating myself a lot but again this is the goal that if you watch this whole video you'll have had this drummed into your head so much that you'll easily remember all the details. Because to me I think this this tumor took me a while to pick up on in my fellowship in sarcoma pathology. I really had",
"corrected_text": " There's some nice collagenous areas and look it's got branching vessels with dense sclerosis around those vessels. That's a pattern you could see in solitary fibrous tumor. Solitary fibrous tumor will usually be CD34 positive. This tumor again low grade fibromyxoid sarcoma is usually negative. I know I'm repeating myself a lot but again this is the goal that if you watch this whole video you'll have had this drummed into your head so much that you'll easily remember all the details. Because to me I think this this tumor took me a while to pick up on in my fellowship in sarcoma pathology. I really had",
"med_umls_ids": "[[{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'branching vessels', 'concept_id': 'C0005847', 'confidence': 0.7352606654167175}, {'entity': 'dense sclerosis', 'concept_id': 'C0036429', 'confidence': 0.8169246912002563}, {'entity': 'vessels', 'concept_id': 'C0005847', 'confidence': 1.0}, {'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}, {'entity': 'solitary fibrous tumor', 'concept_id': 'C1266119', 'confidence': 1.0}], [{'entity': 'Solitary fibrous tumor', 'concept_id': 'C1266119', 'confidence': 1.0}, {'entity': 'CD34', 'concept_id': 'C0054953', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_212",
"caption_rating": "9"
},
{
"": "1005248",
"caption": "A deeper biopsy is needed for a definitive diagnosis of MAC (Morpheaform Basal Cell Carcinoma) because the diagnosis is based on the depth of involvement.",
"image_path": "LlPaENuqzVQ_image_2cc4bea4-52c8-4882-b007-26057577b0f4.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " it'd be very difficult to make a definitive diagnosis. If you just had this, you're sort of SOL. That's why you got to take a deeper biopsy for MAC because that diagnosis is based on the depth of involvement. And you've got to see this kind of pattern to make a definitive diagnosis. So we all have shave biopsies of these. We have a diagnosis called the surface of the sclerosing epithelial neoplasm. You have to go back and take more, another biopsy. MACs often will have a little more squamoid morphology like this. Can you see those kind of eosinophilic cells? They kind of look a little bit more like squamous cells a little bit. So that favors MAC more than like a desmoplastic tricho or even",
"corrected_text": " it'd be very difficult to make a definitive diagnosis. If you just had this, you're sort of SOL. That's why you got to take a deeper biopsy for MAC because that diagnosis is based on the depth of involvement. And you've got to see this kind of pattern to make a definitive diagnosis. So we all have shave biopsies of these. We have a diagnosis called the surface of the sclerosing epithelial neoplasm. You have to go back and take more, another biopsy. MACs often will have a little more squamous morphology like this. Can you see those kind of eosinophilic cells? They kind of look a little bit more like squamous cells a little bit. So that favors MAC more than like a desmoplastic trichilemmoma or even",
"med_umls_ids": "[[{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'MAC', 'concept_id': 'C0009545', 'confidence': 0.9999999403953552}, {'entity': 'Morpheaform Basal Cell Carcinoma', 'concept_id': 'C0555191', 'confidence': 0.9999999403953552}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'depth', 'concept_id': 'C0205125', 'confidence': 1.0}, {'entity': 'involvement', 'concept_id': 'C1314939', 'confidence': 1.0}], [{'entity': 'Squamous', 'concept_id': 'C1182670', 'confidence': 0.9999998807907104}, {'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}, {'entity': 'MAC', 'concept_id': 'C0009545', 'confidence': 0.9999999403953552}], [{'entity': 'Eosinophilic cells', 'concept_id': 'C0682547', 'confidence': 0.8770456314086914}, {'entity': 'MAC', 'concept_id': 'C0009545', 'confidence': 0.9999999403953552}, {'entity': 'squamous cells', 'concept_id': 'C0221910', 'confidence': 0.9999998807907104}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_213",
"caption_rating": "7"
},
{
"": "1007945",
"caption": "Histopathological description of a tumor with big collagen rich rosettes and a prominent round cell appearance around the edge of the rim of the nodules, resembling small round blue cells of a neuroblastoma.",
"image_path": "QDb68_G1HR4_image_aacf1417-2253-4b8d-8465-726c7d25bc75.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Big collagen rich rosettes', 'Prominent round cell appearance around the edge of the rim of the nodules', 'Small round blue cells of a neuroblastoma']",
"noisy_text": " It has also big collagen rich rosettes like this but it has a much more prominent round cell appearance around the edge of the rim of the nodules are very like small round blue cell almost look a little bit like the small round blue cells of a neuroblastoma which is why it's named that way but I've definitely seen pathologists have trouble telling those two apart telling a hyalinizing spindle cell tumor with giant rosettes. This tumor we're looking at here a variation of low-grade fibromyxoid sarcoma I've seen people get that confused with the neuroblastoma-like variant of schwannoma and the difference is important because the schwannoma is even though the name sounds kind of scary is actually benign it has a small round blue cell appearance but it's totally benign variation of schwannoma. S100 should easily solve that problem because S100 would be negative here in low-grade fibromyxoid sarcoma and",
"corrected_text": " It has also big collagen rich rosettes like this but it has a much more prominent round cell appearance around the edge of the rim of the nodules are very like small round blue cell almost look a little bit like the small round blue cells of a neuroblastoma which is why it's named that way but I've definitely seen pathologists have trouble telling those two apart telling a hyalinizing spindle cell tumor with giant rosettes. This tumor we're looking at here a variation of low-grade fibromyxoid sarcoma I've seen people get that confused with the neuroblastoma-like variant of schwannoma and the difference is important because the schwannoma is even though the name sounds kind of scary is actually benign it has a small round blue cell appearance but it's totally benign variation of schwannoma. S100 should easily solve that problem because S100 would be negative here in low-grade fibromyxoid sarcoma and",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'rosettes', 'concept_id': 'C0035863', 'confidence': 0.8847858905792236}, {'entity': 'round cell', 'concept_id': 'C0487470', 'confidence': 1.0}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'edge', 'concept_id': 'C0205154', 'confidence': 1.0}, {'entity': 'rim', 'concept_id': 'C1308727', 'confidence': 1.0}, {'entity': 'nodules', 'concept_id': 'C0028259', 'confidence': 1.0}, {'entity': 'neuroblastoma', 'concept_id': 'C0027819', 'confidence': 1.0}], [{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'variation', 'concept_id': 'C0205419', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'neuroblastoma-like variant of', 'concept_id': 'C1419295', 'confidence': 0.6589864492416382}, {'entity': 'schwannoma', 'concept_id': 'C0027809', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_214",
"caption_rating": "8"
},
{
"": "1006714",
"caption": "Combined melanocytic nevus with features of both a common or benign nevus and a blue nevus.",
"image_path": "8S4LeiO6Bbk_image_fa75fb91-7aa6-4884-bc95-cc3b6603e230.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Dendritic and spindle-shaped melanocytes', 'Heavily pigmented melanophages', 'Sclerotic stroma', 'Combined melanocytic nevus with features of common/benign nevus and blue nevus', 'Dendritic and spindle-shaped melanocytes', 'Heavily pigmented melanophages', 'Sclerotic stroma', 'Combined melanocytic nevus with features of common/benign nevus and blue nevus']",
"noisy_text": " or fusiform-shaped nuclei. They're arranged in short, intersecting vascals. And in between the dendritic and spindled melanocytes, we have very heavily pigmented melanovagias, all set in a sclerotic stroma. So basically, we have here a combined melanocytic nevus, one that has features of both a common or banal nevus and a blue nevus. And this is amongst the most common type of combined melanocytic nevus. By definition, a combined melanocytic nevus has at least two, sometimes more, distinct clonal populations of melanocytes that have a different morphology. And sometimes this is referred to as a true blue nevus because it's a true nevus or a banal nevus and a blue nevus. But it's possible to have all kinds of combinations. We can get a blue nevus with a spitz nevus. We can get balloon cell nevi. Those are combined nevi because you usually have a population of banal appearing melanocytes and balloon melanocytes. At that point, inactivated melanocytic tumors are frequently combined nevi, commonly characterized by banal nevus and a population of very epithelial spits like melanocytes. So anyway, all possible combinations are... And in actuality, a deep penetrating nevus is frequently combined nevus with a combination of banal nevus and what looks oftentimes like a cellular blue nevus. So anyway, this is a combined melanocytic nevus.",
"corrected_text": " or fusiform-shaped nuclei. They're arranged in short, intersecting vessels. And in between the dendritic and spindled melanocytes, we have very heavily pigmented melanophages, all set in a sclerotic stroma. So basically, we have here a combined melanocytic nevus, one that has features of both a common or banal nevus and a blue nevus. And this is amongst the most common type of combined melanocytic nevus. By definition, a combined melanocytic nevus has at least two, sometimes more, distinct clonal populations of melanocytes that have a different morphology. And sometimes this is referred to as a true blue nevus because it's a true nevus or a banal nevus and a blue nevus. But it's possible to have all kinds of combinations. We can get a blue nevus with a spitz nevus. We can get balloon cell nevi. Those are combined nevi because you usually have a population of banal appearing melanocytes and balloon melanocytes. At that point, inactivated melanocytic tumors are frequently combined nevi, commonly characterized by banal nevus and a population of very epithelial spits like melanocytes. So anyway, all possible combinations are... And in actuality, a deep penetrating nevus is frequently combined nevus with a combination of banal nevus and what looks oftentimes like a cellular blue nevus. So anyway, this is a combined melanocytic nevus.",
"med_umls_ids": "[[{'entity': 'Combined', 'concept_id': 'C0205195', 'confidence': 1.0}, {'entity': 'melanocytic nevus', 'concept_id': 'C0027962', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'benign nevus', 'concept_id': 'C1456781', 'confidence': 1.0}, {'entity': 'blue nevus', 'concept_id': 'C0206736', 'confidence': 1.0}], [{'entity': 'Contains', 'concept_id': 'C0332256', 'confidence': 0.9999999403953552}, {'entity': 'clonal populations', 'concept_id': 'C0032659', 'confidence': 0.8110582232475281}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}], [{'entity': 'combinations', 'concept_id': 'C0453882', 'confidence': 1.0}, {'entity': 'combined', 'concept_id': 'C0205195', 'confidence': 1.0}, {'entity': 'nevi', 'concept_id': 'C0027960', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_215",
"caption_rating": "9"
},
{
"": "1005323",
"caption": "Elliptical excision was taken and cut into bread loaves for histological examination.",
"image_path": "LlPaENuqzVQ_image_e989ed10-d52e-4a88-ac90-7846a71da574.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " All right, who wants to give this one a go? Hello, can you hear me? Yeah. Looks like we have multiple deep shaves. Well, wait a second. You've been in the surgery clinic before and you've done a lot of biopsies in your long career now. So this, you think it's really a shave? I take that back. It's probably excision or incisional biopsy. Yeah, yeah, yes, good. This is an excision. So they basically took the elliptical excision. They cut it into bread loaves and put it all on one slide. So that's how",
"corrected_text": " All right, who wants to give this one a go? Hello, can you hear me? Yeah. Looks like we have multiple deep shaves. Well, wait a second. You've been in the surgery clinic before and you've done a lot of biopsies in your long career now. So this, you think it's really a shave? I take that back. It's probably excision or incisional biopsy. Yeah, yeah, yes, good. This is an excision. So they basically took the elliptical excision. They cut it into bread loaves and put it all on one slide. So that's how",
"med_umls_ids": "[[{'entity': 'Multiple', 'concept_id': 'C0439064', 'confidence': 1.0}, {'entity': 'deep shaves', 'concept_id': 'C0518505', 'confidence': 0.7456271648406982}, {'entity': 'excisional/incisional biopsy', 'concept_id': 'C0184921', 'confidence': 0.7826999425888062}], [{'entity': 'Elliptical excision', 'concept_id': 'C1707902', 'confidence': 0.8901858329772949}, {'entity': 'bread', 'concept_id': 'C0006138', 'confidence': 1.0}, {'entity': 'histological examination', 'concept_id': 'C0019637', 'confidence': 0.9535407423973083}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_216",
"caption_rating": "7"
},
{
"": "1006989",
"caption": "Diffuse positive P63 staining expression in prostatic adenocarcinoma, also known as P63 prostate cancer.",
"image_path": "iklRyY1nBIE_image_5b0ad93d-afea-4b34-9971-f890eee96412.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['Prostate cancer with aberrant P63 staining expression.']",
"noisy_text": " Again, you want to look at your internal control. These are the glands that were comfortable or benign. You can see they're staining for both nuclear stain and membranous wispy cytoplasmic stain, which is the hemoglobin cytokeratin. In this baccalaureate case, the racemase was predominantly negative. There's a hint of staining in areas, but it's predominantly negative. What is striking, what is very striking, is the fact that the P63 is diffusely positive, which they found very odd. And so this is a very, very fascinating case of prostatic adenocarcinoma with aberrant P63 expression, or what some people call P63 prostate prostate cancer. And I'll show you, this is the index case, but I'll show you a few other cases. Because it's a very, very fascinating, it's an",
"corrected_text": " Again, you want to look at your internal control. These are the glands that were comfortable or benign. You can see they're staining for both nuclear stain and membranous wispy cytoplasmic stain, which is the hemoglobin cytokeratin. In this baccalaureate case, the racemase was predominantly negative. There's a hint of staining in areas, but it's predominantly negative. What is striking, what is very striking, is the fact that the P63 is diffusely positive, which they found very odd. And so this is a very, very fascinating case of prostatic adenocarcinoma with aberrant P63 expression, or what some people call P63 prostate prostate cancer. And I'll show you, this is the index case, but I'll show you a few other cases. Because it's a very, very fascinating, it's an",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'examination', 'concept_id': 'C0031809', 'confidence': 1.0}, {'entity': 'prostate cancer', 'concept_id': 'C0376358', 'confidence': 1.0}, {'entity': 'staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'nuclear', 'concept_id': 'C0521447', 'confidence': 1.0}, {'entity': 'membranous', 'concept_id': 'C0025255', 'confidence': 1.0}, {'entity': 'wispy cytoplasmic stain', 'concept_id': 'C0010834', 'confidence': 0.6738394498825073}, {'entity': 'hemoglobin cytokeratin', 'concept_id': 'C0010803', 'confidence': 0.7460406422615051}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'racemase', 'concept_id': 'C0034503', 'confidence': 1.0}], [{'entity': 'Diffuse positive P63 staining', 'concept_id': 'C0205219', 'confidence': 0.5406208634376526}, {'entity': 'expression', 'concept_id': 'C0017262', 'confidence': 0.9999998807907104}, {'entity': 'prostatic adenocarcinoma', 'concept_id': 'C0007112', 'confidence': 1.0}, {'entity': 'P63 prostate cancer', 'concept_id': 'C0376358', 'confidence': 0.7053087949752808}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_217",
"caption_rating": "7"
},
{
"": "1008278",
"caption": "Muscle should only be present in the muscularis mucosa, but hyperplasia can cause muscle bundles to extend into the lamina propria.",
"image_path": "r7OA0Trj5hQ_image_12588514-8bd8-4cc3-b1a3-05e9f8138c11.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Muscle coming in the lamina propria', 'Muscularis mucosa is hyperplastic', 'Muscle coming in the lamina propria', 'Muscularis mucosa is hyperplastic', 'Muscle coming in the lamina propria', 'Muscularis mucosa is hyperplastic']",
"noisy_text": " The epithelium, the glands are pushed apart each other. And this may be procedure related. This may be seen in chemical gastritis, lamina propria. It's a very nonspecific finding, not diagnostic of anything. But whenever you see, think of chemical gastritis. This is muscularization. You see in the hyperwire, muscle coming in the lamina propria. Lamina propria should be free of musculature. The muscle should be there only in the muscularis mucosa. Here in this low power, you can see the muscularis mucosa is hyperplastic. And it is sending the muscle bundle into the lamina propria. This happens in chemical gastritis in case of stomach and in",
"corrected_text": " The epithelium, the glands are pushed apart each other. And this may be procedure related. This may be seen in chemical gastritis, lamina propria. It's a very nonspecific finding, not diagnostic of anything. But whenever you see, think of chemical gastritis. This is muscularization. You see in the hyperplasia, muscle coming in the lamina propria. Lamina propria should be free of musculature. The muscle should be there only in the muscularis mucosa. Here in this low power, you can see the muscularis mucosa is hyperplastic. And it is sending the muscle bundle into the lamina propria. This happens in chemical gastritis in case of stomach and in",
"med_umls_ids": "[[{'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'procedure-related', 'concept_id': 'C2924519', 'confidence': 1.0}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}], [{'entity': 'Muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'nonspecific', 'concept_id': 'C0750540', 'confidence': 1.0}, {'entity': 'finding', 'concept_id': 'C0037088', 'confidence': 1.0}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}], [{'entity': 'Muscle', 'concept_id': 'C0026845', 'confidence': 1.0}, {'entity': 'muscularis mucosa', 'concept_id': 'C0225357', 'confidence': 0.9999998807907104}, {'entity': 'hyperplasia', 'concept_id': 'C0020507', 'confidence': 1.0}, {'entity': 'muscle bundles', 'concept_id': 'C0504095', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}], [{'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_218",
"caption_rating": "9"
},
{
"": "1005792",
"caption": "IMHMV is a condition commonly seen in young males, and may be due to fistula formation between the artery and vein, possibly caused by trauma.",
"image_path": "r7OA0Trj5hQ_image_e5cecb68-5ee7-45aa-a1cb-bcf5886383ca.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Venous tubules or venous branches in the lamina propria', 'Distinct cells with foamy cytoplasm and centrally placed nucleus', 'Venous tubules or venous branches in the lamina propria', 'Distinct cells with foamy cytoplasm and centrally placed nucleus']",
"noisy_text": " probably venous tubules or venous branches in the lamina propria. So very characteristic of this IMHMV. And the exact cause is not known. They are predicting it is more like a fistula formation between the artery and vein, like an AV malformation, maybe due to trauma. It is commonly seen in young males, and they present with the signs and symptoms of inflammatory bowel disease. Interesting condition. Here, the lamina propria is full of cells with a distinct cell border, abundant foamy cytoplasm, most of the time centrally placed nucleus. Sometimes it is pushed to the periphery. The central nuclear",
"corrected_text": " probably venous tubules or venous branches in the lamina propria. So very characteristic of this IMHMV. And the exact cause is not known. They are predicting it is more like a fistula formation between the artery and vein, like an AV malformation, maybe due to trauma. It is commonly seen in young males, and they present with the signs and symptoms of inflammatory bowel disease. Interesting condition. Here, the lamina propria is full of cells with a distinct cell border, abundant foamy cytoplasm, most of the time centrally placed nucleus. Sometimes it is pushed to the periphery. The central nuclear",
"med_umls_ids": "[[{'entity': 'Venous tubules', 'concept_id': 'C0022674', 'confidence': 0.6645606160163879}, {'entity': 'venous branches', 'concept_id': 'C0042449', 'confidence': 0.6472384333610535}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'inflammatory bowel disease', 'concept_id': 'C0021390', 'confidence': 1.0}], [{'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'young', 'concept_id': 'C0332239', 'confidence': 1.0}, {'entity': 'males', 'concept_id': 'C0086582', 'confidence': 1.0}, {'entity': 'fistula', 'concept_id': 'C0016169', 'confidence': 1.0}, {'entity': 'formation', 'concept_id': 'C0220781', 'confidence': 1.0}, {'entity': 'artery', 'concept_id': 'C0003842', 'confidence': 1.0}, {'entity': 'vein', 'concept_id': 'C0042449', 'confidence': 1.0}, {'entity': 'trauma', 'concept_id': 'C0043251', 'confidence': 0.9999999403953552}], [{'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'cell border', 'concept_id': 'C0205284', 'confidence': 0.773768424987793}, {'entity': 'foamy cytoplasm', 'concept_id': 'C0010834', 'confidence': 0.7207725048065186}, {'entity': 'centrally', 'concept_id': 'C0205099', 'confidence': 0.7070305943489075}, {'entity': 'nucleus', 'concept_id': 'C0007610', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_219",
"caption_rating": "8"
},
{
"": "1008222",
"caption": "Different types of nuclei are observed, including hyperchromatic and vesicular nuclei.",
"image_path": "Wiyo6taYRF4_image_f2fd3cc2-b10f-44d2-aa3a-167b1cde6571.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Hematopathology', 'Neuropathology', 'Cytopathology']",
"roi_text": "['neuroendocrine carcinoma', 'hyperchromatic nuclei', 'vesicular nuclei', 'nucleoli', 'salt and pepper chromatin', 'nucleoli', 'salt and pepper chromatin']",
"noisy_text": " and pepper like copper chromatin, that means you're telling that this is most likely a neuroendocrine kind of a carcinoma. So those are the different types of nuclei that we have seen. Again, to go back at the reference, we are going to look at the plasma cell. In the plasma cell, we can easily identify the hetero and the vesicular areas, that is heterochromatin and nucleomatin. If the cell is entirely composed of heterochromatin, it will be very dark-staining. And this is called as hyperchromatic nuclei. If it is composed of lightly-stained nuclei, lightly-stained areas, then it is called vesicular nuclei. A vesicular nuclei is usually accompanied by a nucleoli. And if you have very finely granular dark and light areas, then it is called as salt and pepper chromatin. And these are the defining features for a neuroendocrine tumor. Now, once we have understood the staining pattern of the",
"corrected_text": " and pepper like copper chromatin, that means you're telling that this is most likely a neuroendocrine kind of a carcinoma. So those are the different types of nuclei that we have seen. Again, to go back at the reference, we are going to look at the plasma cell. In the plasma cell, we can easily identify the hetero and the vesicular areas, that is heterochromatin and nucleoplasm. If the cell is entirely composed of heterochromatin, it will be very hyperchromatic. And this is called as hyperchromatic nuclei. If it is composed of lightly-stained areas, lightly-stained areas, then it is called vesicular nuclei. A vesicular nuclei is usually accompanied by a nucleoli. And if you have very finely granular dark and light areas, then it is called as salt and pepper chromatin. And these are the defining features for a neuroendocrine tumor. Now, once we have understood the staining pattern of the",
"med_umls_ids": "[[{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'pepper-like copper chromatin', 'concept_id': 'C0453397', 'confidence': 0.5605897903442383}, {'entity': 'neuroendocrine carcinoma', 'concept_id': 'C0206695', 'confidence': 1.0}], [{'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'observed', 'concept_id': 'C1441672', 'confidence': 1.0}, {'entity': 'hyperchromatic', 'concept_id': 'C0333911', 'confidence': 1.0}, {'entity': 'vesicular nuclei', 'concept_id': 'C2325471', 'confidence': 0.7651268839836121}], [{'entity': 'Heterochromatin', 'concept_id': 'C0019397', 'confidence': 1.0}, {'entity': 'nucleoplasm', 'concept_id': 'C0682537', 'confidence': 1.0}, {'entity': 'identified', 'concept_id': 'C0205396', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}], [{'entity': 'Vesicular nuclei', 'concept_id': 'C2325471', 'confidence': 0.7651268839836121}, {'entity': 'nucleoli', 'concept_id': 'C0007609', 'confidence': 0.8710004091262817}], [{'entity': 'Salt', 'concept_id': 'C0036140', 'confidence': 1.0}, {'entity': 'pepper chromatin', 'concept_id': 'C0008546', 'confidence': 0.7025638818740845}, {'entity': 'neuroendocrine tumor', 'concept_id': 'C0206754', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1152.0",
"id": "test_220",
"caption_rating": "8"
},
{
"": "1007472",
"caption": "Example of atrophy with no defined number of glands due to age and size dependence.",
"image_path": "r7OA0Trj5hQ_image_1071a4a6-9553-4086-90ce-c698e5b9f6e4.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['acinar structures resembling pancreas', 'pancreatic acinar-like structures in the GIT', 'acinar structures resembling pancreas', 'pancreatic acinar-like structures in the GIT']",
"noisy_text": " Sometimes the stomach can show acinar structures resembling pancreas. Then it is known as pancreatic acinar metaplasia. This can also happen in the small intestine. There, when you do staining for amylase or trypsin, it will be positive, but on H&E itself, you can see pancreatic acinar-like structures in the GIT. Then it will become pancreatic acinar metaplasia. Here is the best example of atrophy. Again, unfortunately, there is no defined number of glands to be seen because this is age-dependentation, size-dependentation, race-dependent. So",
"corrected_text": " Sometimes the stomach can show acinar structures resembling pancreas. Then it is known as pancreatic acinar metaplasia. This can also happen in the small intestine. There, when you do staining for amylase or trypsin, it will be positive, but on H&E itself, you can see pancreatic acinar-like structures in the GIT. Then it will become pancreatic acinar metaplasia. Here is the best example of atrophy. Again, unfortunately, there is no defined number of glands to be seen because this is age-dependentation, size-dependentation, race-dependent. So",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'pancreatic acinar metaplasia', 'concept_id': 'C4021967', 'confidence': 0.7844848036766052}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'small intestine', 'concept_id': 'C0021852', 'confidence': 1.0}], [{'entity': 'Staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'amylase', 'concept_id': 'C0002712', 'confidence': 1.0}, {'entity': 'trypsin', 'concept_id': 'C0041236', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'intestine', 'concept_id': 'C0021853', 'confidence': 1.0}], [{'entity': 'atrophy', 'concept_id': 'C0333641', 'confidence': 1.0}, {'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'age', 'concept_id': 'C0001779', 'confidence': 1.0}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'dependence', 'concept_id': 'C0011546', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_221",
"caption_rating": "7"
},
{
"": "1008764",
"caption": "No internal elastic lamina seen in the image.",
"image_path": "r7OA0Trj5hQ_image_febb4bba-96f0-4103-8059-ff8932c75cdf.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Severe dysplasia', 'Thick and thin blood vessels', 'Thick vessel wall', 'Narrowing of lumen', 'Vein and artery identification', 'No internal elastic lamina']",
"noisy_text": " And in the resection, you see like a heavy malformation, isn't it? Thick and thin blood vessels of varying sizes are seen. In high power, you can see very thick vessel wall with the narrowing of the lumen, whereas here, it is relatively preserved. So you want to know whether it is a vein or artery. Please believe me, this is a vein, and this is an artery. And that is proved by the elastic tissue strain. These are all pictures from Dr. Gonzalez's Twitter. And you can see here, there is no internal elastic lamina, whereas here,",
"corrected_text": " And in the resection, you see like a heavy malformation, isn't it? Thick and thin blood vessels of varying sizes are seen. In high power, you can see very thick vessel wall with the narrowing of the lumen, whereas here, it is relatively preserved. So you want to know whether it is a vein or artery. Please believe me, this is a vein, and this is an artery. And that is proved by the elastic tissue strain. These are all pictures from Dr. Gonzalez's Twitter. And you can see here, there is no internal elastic lamina, whereas here,",
"med_umls_ids": "[[{'entity': 'Severe', 'concept_id': 'C0205082', 'confidence': 1.0}, {'entity': 'resection', 'concept_id': 'C0015252', 'confidence': 1.0}], [{'entity': 'Thick', 'concept_id': 'C1280412', 'confidence': 1.0}, {'entity': 'thin', 'concept_id': 'C0205168', 'confidence': 1.0}, {'entity': 'sizes', 'concept_id': 'C0456389', 'confidence': 1.0}], [{'entity': 'Thick vessel wall', 'concept_id': 'C1180033', 'confidence': 0.6420797109603882}, {'entity': 'narrowing', 'concept_id': 'C0332463', 'confidence': 1.0}, {'entity': 'lumen', 'concept_id': 'C0524461', 'confidence': 0.9999998807907104}, {'entity': 'power', 'concept_id': 'C0032863', 'confidence': 1.0}], [{'entity': 'Identification', 'concept_id': 'C0020792', 'confidence': 1.0}, {'entity': 'vein', 'concept_id': 'C0042449', 'confidence': 1.0}, {'entity': 'artery', 'concept_id': 'C0003842', 'confidence': 1.0}, {'entity': 'elastic tissue', 'concept_id': 'C0013762', 'confidence': 1.0}, {'entity': 'strain', 'concept_id': 'C0080194', 'confidence': 1.0}], [{'entity': 'image', 'concept_id': 'C1696103', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_222",
"caption_rating": "8"
},
{
"": "1004573",
"caption": "Normal epithelium, low-grade dysplasia, and high-grade dysplasia can be seen in one picture.",
"image_path": "r7OA0Trj5hQ_image_3ab9b09a-230e-4d73-8ba3-400b1477d871.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Stroma running in between', 'Crowded appearance', 'Back-to-back glands', 'Cribriform appearance', 'Intraglandular epithelial proliferation', 'Stroma running in between', 'Crowded appearance', 'Back-to-back glands', 'Cribriform appearance', 'Intraglandular epithelial proliferation']",
"noisy_text": " you can see some stroma running in between. However, it may be crowded. See here, one gland, another gland. You can see the nice stroma in between. These are back-to-back glands. But see here, this is one gland, this is one gland, this is one gland. But no stroma in between. So these are cribriform, which is intraglandular. Epithelial proliferation is happening within the gland, which is a future of high-grade dysplasia. So normal epithelium, low-grade dysplasia, high-grade dysplasia in one picture. Thanks to Google. I don't know the source, but I thank the person, anonymous person. So those are",
"corrected_text": " you can see some stroma running in between. However, it may be crowded. See here, one gland, another gland. You can see the nice stroma in between. These are back-to-back glands. But see here, this is one gland, this is one gland, this is one gland. But no stroma in between. So these are cribriform, which is intraglandular. Epithelial proliferation is happening within the gland, which is a future of high-grade dysplasia. So normal epithelium, low-grade dysplasia, high-grade dysplasia in one picture. Thanks to Google. I don't know the source, but I thank the person, anonymous person. So those are",
"med_umls_ids": "[[{'entity': 'Intraglandular', 'concept_id': 'C4725341', 'confidence': 0.9096097350120544}, {'entity': 'epithelial proliferation', 'concept_id': 'C0334097', 'confidence': 1.0}, {'entity': 'high-grade dysplasia', 'concept_id': 'C1333110', 'confidence': 0.8831341862678528}], [{'entity': 'Normal epithelium', 'concept_id': 'C0014609', 'confidence': 0.8199569582939148}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'dysplasia', 'concept_id': 'C0334044', 'confidence': 1.0}, {'entity': 'high-grade dysplasia', 'concept_id': 'C1333110', 'confidence': 0.8831341862678528}, {'entity': 'picture', 'concept_id': 'C0441468', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_223",
"caption_rating": "8"
},
{
"": "1009474",
"caption": "EMA, Clodin-1, and Glut-1 are immunohistochemical stains that can help diagnose perineuriomas, but low-grade fibrosarcomas can also express EMA and Clodin-1.",
"image_path": "QDb68_G1HR4_image_1e4ca39c-40f6-492b-b7c7-c8e20bfaf5f5.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Deep soft tissue', 'Perineurioma', 'Low-grade fibromyxoid sarcoma', 'Immunohistochemistry', 'Swirling growth']",
"noisy_text": " involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is more of a difficult problem because perineurioma has a lot of overlap histologically with low-grade fibromyxoid sarcoma and also immunohistochemically. On immunostains, EMA, Clodin-1 and Glut-1 are three immunostains that will usually stain perineuriomas. The problem is that low-grade fibromyxoid sarcomas often express at least focal EMA, so that's a problem and additionally, the examples of low-grade fibromyxoid sarcoma that have dramatic swirling and whirling growth, those are the ones that have a perineurioma like pattern, the ones that mimic perineurioma. They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The",
"corrected_text": " involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is more of a difficult problem because perineurioma has a lot of overlap histologically with low-grade fibromyxoid sarcoma and also immunohistochemically. On immunostains, EMA, Clodin-1 and Glut-1 are three immunostains that will usually stain perineuriomas. The problem is that low-grade fibromyxoid sarcomas often express at least focal EMA, so that's a problem and additionally, the examples of low-grade fibromyxoid sarcoma that have dramatic swirling and whirling growth, those are the ones that have a perineurioma like pattern, the ones that mimic perineurioma. They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The",
"med_umls_ids": "[[{'entity': 'CD34', 'concept_id': 'C0054953', 'confidence': 1.0}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'deep soft tissue tumors', 'concept_id': 'C0037579', 'confidence': 0.8622524738311768}], [{'entity': 'Perineurioma', 'concept_id': 'C0751691', 'confidence': 0.9999999403953552}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'histologically', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'immunohistochemistry', 'concept_id': 'C0021044', 'confidence': 0.9999998807907104}], [{'entity': 'EMA', 'concept_id': 'C0268596', 'confidence': 0.9999999403953552}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}, {'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'immunohistochemical stains', 'concept_id': 'C4317108', 'confidence': 0.9999999403953552}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibrosarcomas', 'concept_id': 'C0016057', 'confidence': 1.0}, {'entity': 'EMA', 'concept_id': 'C0268596', 'confidence': 0.9999999403953552}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}], [{'entity': 'Low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'swirling', 'concept_id': 'C0233591', 'confidence': 0.7064549922943115}, {'entity': 'growth', 'concept_id': 'C0018270', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'express', 'concept_id': 'C0017262', 'confidence': 0.8176293969154358}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}], [{'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'reports', 'concept_id': 'C0684224', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcomas', 'concept_id': 'C1275282', 'confidence': 0.8123146891593933}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_224",
"caption_rating": "8"
},
{
"": "1006951",
"caption": "Psoriasiform hyperplasia is also present, but the diagnosis of seborrheic dermatitis is favored over psoriasis.",
"image_path": "udoW6VSqsm4_image_10f1e59c-526f-45f9-9d88-cc22c8463445.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " Now what's this pattern, what are we looking at right here? What's the histologic reaction pattern? Oh, it's the spongiosis. Some spongiosis. So you can see some spongiosis in sep-derm, just like that case last night that you guys presented had spongiosis and psoriasiform hyperplasia. You can see some spongiosis in sep-derm, so it doesn't mean that they have allergic contact dermatitis or anything like that. So this is pretty good for sep-derm. If you want to say, well, there's a little more psoriasiform hyperplasia than usual there for seiboceriasis, try to avoid the term seiboceriasis because it's kind of a wastebasket a little bit. It doesn't commit to one diagnosis or the other. So I would favor sep-derm here more so than psoriasis, but it's a little more psoriasiform than usual. These are the clinical photos. You guys all know all about sep-derms.",
"corrected_text": " Now what's this pattern, what are we looking at right here? What's the histologic reaction pattern? Oh, it's the spongiosis. Some spongiosis. So you can see some spongiosis in sep-derm, just like that case last night that you guys presented had spongiosis and psoriasiform hyperplasia. You can see some spongiosis in sep-derm, so it doesn't mean that they have allergic contact dermatitis or anything like that. So this is pretty good for sep-derm. If you want to say, well, there's a little more psoriasiform hyperplasia than usual there for seborrheic dermatitis, try to avoid the term seborrheic dermatitis because it's kind of a wastebasket a little bit. It doesn't commit to one diagnosis or the other. So I would favor sep-derm here more so than psoriasis, but it's a little more psoriasiform than usual. These are the clinical photos. You guys all know all about sep-derms.",
"med_umls_ids": "[[{'entity': 'Spongiosis', 'concept_id': 'C0702120', 'confidence': 1.0}, {'entity': 'histologic reaction', 'concept_id': 'C0205462', 'confidence': 0.8118124008178711}], [{'entity': 'Spongiosis', 'concept_id': 'C0702120', 'confidence': 1.0}, {'entity': 'seborrheic dermatitis', 'concept_id': 'C0036508', 'confidence': 1.0}], [{'entity': 'Psoriasiform hyperplasia', 'concept_id': 'C3281279', 'confidence': 0.9999999403953552}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'seborrheic dermatitis', 'concept_id': 'C0036508', 'confidence': 1.0}, {'entity': 'psoriasis', 'concept_id': 'C0033860', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_225",
"caption_rating": "9"
},
{
"": "1005555",
"caption": "Cribriform pattern and loose, edematous, and vascular stroma.",
"image_path": "8S4LeiO6Bbk_image_291b76ac-03b4-4785-b160-fbc9a7bc08fa.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['epithelial tumor', 'cytoplasm', 'vesicular chromatin pattern', 'lymphocytes', 'duct formation', 'epithelial tumor', 'cytoplasm', 'vesicular chromatin pattern', 'lymphocytes', 'duct formation']",
"noisy_text": " If we move to higher power, we can see that we're dealing with an epithelial rather than a mosaicable tumor. We've got interconnected cords and strands. We have somewhat of a ribiform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of the cells are round to oval. They're fairly large. These cells have some faint eosinophilic to pale gray cytoplasm, although this cytoplasm is kind of difficult to see. Some of these cells have an evenly dispersed or vesicular chromatin pattern, and other nuclei are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and",
"corrected_text": " If we move to higher power, we can see that we're dealing with an epithelial rather than a mesenchymal tumor. We've got interconnected cords and strands. We have somewhat of a cribriform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of the cells are round to oval. They're fairly large. These cells have some faint eosinophilic to pale gray cytoplasm, although this cytoplasm is kind of difficult to see. Some of these cells have an evenly dispersed or vesicular chromatin pattern, and other nuclei are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'epithelial tumor', 'concept_id': 'C1368683', 'confidence': 0.9999999403953552}, {'entity': 'cords', 'concept_id': 'C0034869', 'confidence': 0.801885187625885}, {'entity': 'strands', 'concept_id': 'C0600383', 'confidence': 0.800572395324707}], [{'entity': 'Cribriform pattern', 'concept_id': 'C1333163', 'confidence': 1.0}, {'entity': 'loose', 'concept_id': 'C0205407', 'confidence': 1.0}, {'entity': 'edematous', 'concept_id': 'C0013604', 'confidence': 1.0}, {'entity': 'vascular stroma', 'concept_id': 'C0005847', 'confidence': 0.8046398758888245}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'cell types', 'concept_id': 'C0007634', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'eosinophilic', 'concept_id': 'C0333930', 'confidence': 1.0}, {'entity': 'pale', 'concept_id': 'C0030232', 'confidence': 1.0}, {'entity': 'gray cytoplasm', 'concept_id': 'C0010834', 'confidence': 0.8177905678749084}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'duct', 'concept_id': 'C0687028', 'confidence': 1.0}, {'entity': 'formation', 'concept_id': 'C0220781', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "1.0",
"height": "758.0",
"width": "1920.0",
"id": "test_226",
"caption_rating": "8"
},
{
"": "1004737",
"caption": "Presence of dilated vessels running parallel to the epithelial surface is a finding that suggests a diagnosis.",
"image_path": "sDFjOtMAYrk_image_a2bbf82c-4704-4b6c-b9dc-1bbb2411ba4e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['Dilated vessels running parallel to the epithelial surface.']",
"noisy_text": " This patient had a history of radiation also for prostate cancer, but the pattern is a little bit different. Yes, the lamina propria is a little bit hyalinized and maybe there's some architectural distortion, but it looks less striking than the other one. And you don't have a good, juicy, hyalinized vessel to really tip you off, but you have another finding to tip you off. And that would be this. These dilated vessels that run parallel to the epithelial surface. And you'll see dilated vessels. Oh, this is a good one right here. Dilated vessels that tend to run parallel to the epithelial",
"corrected_text": " This patient had a history of radiation also for prostate cancer, but the pattern is a little bit different. Yes, the lamina propria is a little bit hyalinized and maybe there's some architectural distortion, but it looks less striking than the other one. And you don't have a good, juicy, hyalinized vessel to really tip you off, but you have another finding to tip you off. And that would be this. These dilated vessels that run parallel to the epithelial surface. And you'll see dilated vessels. Oh, this is a good one right here. Dilated vessels that tend to run parallel to the epithelial",
"med_umls_ids": "[[{'entity': 'Patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'history', 'concept_id': 'C0019664', 'confidence': 1.0}, {'entity': 'radiation', 'concept_id': 'C0034519', 'confidence': 1.0}, {'entity': 'prostate cancer', 'concept_id': 'C0376358', 'confidence': 1.0}], [{'entity': 'Lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'hyalinized', 'concept_id': 'C0332230', 'confidence': 1.0}, {'entity': 'architectural distortion', 'concept_id': 'C2826609', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'dilated vessels running', 'concept_id': 'C0424830', 'confidence': 0.6464064121246338}, {'entity': 'epithelial surface', 'concept_id': 'C2327105', 'confidence': 0.9104864597320557}, {'entity': 'finding', 'concept_id': 'C0037088', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_227",
"caption_rating": "7"
},
{
"": "1008277",
"caption": "Muscularization in the lamina propria is a nonspecific finding, but may indicate chemical gastritis.",
"image_path": "r7OA0Trj5hQ_image_12588514-8bd8-4cc3-b1a3-05e9f8138c11.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Muscle coming in the lamina propria', 'Muscularis mucosa is hyperplastic', 'Muscle coming in the lamina propria', 'Muscularis mucosa is hyperplastic', 'Muscle coming in the lamina propria', 'Muscularis mucosa is hyperplastic']",
"noisy_text": " The epithelium, the glands are pushed apart each other. And this may be procedure related. This may be seen in chemical gastritis, lamina propria. It's a very nonspecific finding, not diagnostic of anything. But whenever you see, think of chemical gastritis. This is muscularization. You see in the hyperwire, muscle coming in the lamina propria. Lamina propria should be free of musculature. The muscle should be there only in the muscularis mucosa. Here in this low power, you can see the muscularis mucosa is hyperplastic. And it is sending the muscle bundle into the lamina propria. This happens in chemical gastritis in case of stomach and in",
"corrected_text": " The epithelium, the glands are pushed apart each other. And this may be procedure related. This may be seen in chemical gastritis, lamina propria. It's a very nonspecific finding, not diagnostic of anything. But whenever you see, think of chemical gastritis. This is muscularization. You see in the hyperplasia, muscle coming in the lamina propria. Lamina propria should be free of musculature. The muscle should be there only in the muscularis mucosa. Here in this low power, you can see the muscularis mucosa is hyperplastic. And it is sending the muscle bundle into the lamina propria. This happens in chemical gastritis in case of stomach and in",
"med_umls_ids": "[[{'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'procedure-related', 'concept_id': 'C2924519', 'confidence': 1.0}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}], [{'entity': 'Muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'nonspecific', 'concept_id': 'C0750540', 'confidence': 1.0}, {'entity': 'finding', 'concept_id': 'C0037088', 'confidence': 1.0}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}], [{'entity': 'Muscle', 'concept_id': 'C0026845', 'confidence': 1.0}, {'entity': 'muscularis mucosa', 'concept_id': 'C0225357', 'confidence': 0.9999998807907104}, {'entity': 'hyperplasia', 'concept_id': 'C0020507', 'confidence': 1.0}, {'entity': 'muscle bundles', 'concept_id': 'C0504095', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}], [{'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_228",
"caption_rating": "9"
},
{
"": "1009060",
"caption": "The tissue sample shows a spectrum of histologic changes that can make diagnosis challenging.",
"image_path": "sDFjOtMAYrk_image_753098ed-78a1-48fe-9161-c80014af8021.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['neutrophils and lymphocytes', 'plasma cells in the lamina propria', 'histiocytes in the lamina propria', 'neutrophils and lymphocytes', 'plasma cells in the lamina propria', 'histiocytes in the lamina propria']",
"noisy_text": " neutrophils and lymphocytes. And some cases have predominantly plasma cells in the lamina propria. Some cells have predominantly histiocytes in the lamina propria. I used to think when we started recognizing these that all of the cases look the same, but we've learned in the past couple of years that there's a spectrum of histologic changes that can make it really challenging. The good thing about this case is we do have the immuno at Hopkins. Immuno will be negative in the vast majority of these cases, but once in a while you'll catch one positive case. And this is one of those. I",
"corrected_text": " neutrophils and lymphocytes. And some cases have predominantly plasma cells in the lamina propria. Some cells have predominantly histiocytes in the lamina propria. I used to think when we started recognizing these that all of the cases look the same, but we've learned in the past couple of years that there's a spectrum of histologic changes that can make it really challenging. The good thing about this case is we do have the immuno at Hopkins. Immuno will be negative in the vast majority of these cases, but once in a while you'catch one positive case. And this is one of those. I",
"med_umls_ids": "[[{'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'spectrum', 'concept_id': 'C1883073', 'confidence': 1.0}, {'entity': 'histologic', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'changes', 'concept_id': 'C0392747', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'immuno test', 'concept_id': 'C0021061', 'confidence': 0.7767297029495239}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_229",
"caption_rating": "8"
},
{
"": "1007380",
"caption": "Distinguishing low-grade fibromyxoid sarcoma from myxofibrosarcoma can be done histologically with H and E staining.",
"image_path": "QDb68_G1HR4_image_114a1dc1-415a-422a-8de0-5b6ca40b88d5.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " So by that time the patient may have moved, forgotten all about the supposedly benign mass they had removed years and years ago and so that's why it took a long time for people to figure out that this was actually a malignancy. So the way that I'm making a separate video which I'll put a link up in the upper right hand corner here and also in the video description, I'm making a video to quickly explain a quick overview of explaining how to tell apart low grade fibromyxoid sarcoma from myxofibrosarcoma. The names sound similar but they're very different tumors histologically and are easy to separate most of the time just on H and E. But this video is going to be all about low grade fibromyxoid sarcoma so this is the more in-depth look",
"corrected_text": " So by that time the patient may have moved, forgotten all about the supposedly benign mass they had removed years and years ago and so that's why it took a long time for people to figure out that this was actually a malignancy. So the way that I'm making a separate video which I'll put a link up in the upper right hand corner here and also in the video description, I'm making a video to quickly explain a quick overview of explaining how to tell apart low grade fibromyxoid sarcoma from myxofibrosarcoma. The names sound similar but they're very different tumors histologically and are easy to separate most of the time just on H and E. But this video is going to be all about low grade fibromyxoid sarcoma so this is the more in-depth look",
"med_umls_ids": "[[{'entity': 'benign mass', 'concept_id': 'C0741729', 'confidence': 0.824069619178772}, {'entity': 'malignancy', 'concept_id': 'C0006826', 'confidence': 1.0}], [{'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'myxofibrosarcoma', 'concept_id': 'C3714524', 'confidence': 1.0}, {'entity': 'histologically', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'H', 'concept_id': 'C0011892', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_230",
"caption_rating": "8"
},
{
"": "1007430",
"caption": "Chemotherapy associated colitis can mimic inflammatory bowel disease.",
"image_path": "sDFjOtMAYrk_image_f5e1c62e-602e-4f58-823f-8c8d482be39e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "[]",
"noisy_text": " they're receiving radiation, is a lot of eosinophils and even intracryptal eosinophilic microapses. You don't see a lot in the way of neutrophils. You may see some neutrophils in the cytoplasm of the nuclei, like intracellular intracytoplasmic neutrophils, but not really neutrophilic microapses. And the other thing you might see is intracytoplasmic vacuoles degenerating vacuoles. So, this is a good example of chemotherapy associated colitis, a mimic of inflammatory bowel disease. Oh, this is a good one. With that degree, the mild degree of architectural distortion is what's making me fall short of saying this is for sure IBD. So, I would be descriptive and I would say, you know,",
"corrected_text": " they're receiving radiation, is a lot of eosinophils and even intracryptal eosinophilic microapses. You don't see a lot in the way of neutrophils. You may see some neutrophils in the cytoplasm of the nuclei, like intracellular intracytoplasmic neutrophils, but not really neutrophilic microapses. And the other thing you might see is intracytoplasmic vacuoles degenerating vacuoles. So, this is a good example of chemotherapy associated colitis, a mimic of inflammatory bowel disease. Oh, this is a good one. With that degree, the mild degree of architectural distortion is what's making me fall short of saying this is for sure IBD. So, I would be descriptive and I would say, you know,",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'intracryptal', 'concept_id': 'C3315370', 'confidence': 0.626490592956543}, {'entity': 'microapses', 'concept_id': 'C0700712', 'confidence': 0.5626617074012756}, {'entity': 'patients', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'radiation', 'concept_id': 'C0034519', 'confidence': 1.0}], [{'entity': 'intracellular', 'concept_id': 'C0175996', 'confidence': 1.0}, {'entity': 'intracytoplasmic', 'concept_id': 'C0230649', 'confidence': 0.8670988082885742}, {'entity': 'neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'degenerating', 'concept_id': 'C0011164', 'confidence': 1.0}, {'entity': 'vacuoles', 'concept_id': 'C0042219', 'confidence': 1.0}], [{'entity': 'Chemotherapy', 'concept_id': 'C0013216', 'confidence': 1.0}, {'entity': 'colitis', 'concept_id': 'C0009319', 'confidence': 1.0}, {'entity': 'inflammatory bowel disease', 'concept_id': 'C0021390', 'confidence': 1.0}], [{'entity': 'Mild', 'concept_id': 'C1513302', 'confidence': 1.0}, {'entity': 'degree', 'concept_id': 'C0441889', 'confidence': 1.0}, {'entity': 'architectural distortion', 'concept_id': 'C2826609', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_231",
"caption_rating": "8"
},
{
"": "1006572",
"caption": "MUC4 stain is used to confirm the diagnosis of cellular intramuscular myxoma.",
"image_path": "QDb68_G1HR4_image_9663f836-2793-4daf-9f55-9b76c5b0cf75.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['myxoid features', 'fine delicate collagen', 'cellular intramuscular myxoma', 'fibrous areas', 'cellular areas', 'MUC4 stain', 'myxoid features', 'fine delicate collagen', 'cellular intramuscular myxoma', 'fibrous areas', 'cellular areas', 'MUC4 stain']",
"noisy_text": " Here's again the myxoid background I really think this is very helpful. The very very fine delicate collagen that you see. Now areas like this I think can kind of resemble what you see in a so-called cellular intramuscular myxoma. Intramuscular myxomas are usually very blue and myxoid very hypocellular but sometimes they get more fibrous and more cellular areas. And on a needle biopsy I think that can be challenging. So I think usually with some experience you can tell them apart on H and E most of the time but when I have any doubt I just do a MUC4 stain. The MUC4 is negative and on a needle it looks like a myxoma with some kind of fibrous or a little bit more cellular areas and then I just say that it's probably a cellular intramuscular myxoma. So I think MUC4",
"corrected_text": " Here's again the myxoid background I really think this is very helpful. The very very fine delicate collagen that you see. Now areas like this I think can kind of resemble what you see in a so-called cellular intramuscular myxoma. Intramuscular myxomas are usually very blue and myxoid very hypocellular but sometimes they get more fibrous and more cellular areas. And on a needle biopsy I think that can be challenging. So I think usually with some experience you can tell them apart on H and E most of the time but when I have any doubt I just do a MUC4 stain. The MUC4 is negative and on a needle it looks like a myxoma with some kind of fibrous or a little bit more cellular areas and then I just say that it's probably a cellular intramuscular myxoma. So I think MUC4",
"med_umls_ids": "[[{'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'myxoid', 'concept_id': 'C0205295', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}], [{'entity': 'narrator', 'concept_id': 'C1135957', 'confidence': 0.7711340188980103}, {'entity': 'cellular', 'concept_id': 'C0007634', 'confidence': 0.9999999403953552}, {'entity': 'intramuscular', 'concept_id': 'C0442117', 'confidence': 1.0}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}, {'entity': 'cellular areas', 'concept_id': 'C0007634', 'confidence': 0.7882957458496094}], [{'entity': 'MUC4', 'concept_id': 'C1417496', 'confidence': 0.9999999403953552}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'confirm', 'concept_id': 'C0521093', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'cellular intramuscular myxoma', 'concept_id': 'C1334260', 'confidence': 0.8910117149353027}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_232",
"caption_rating": "9"
},
{
"": "1008762",
"caption": "Thick vessel wall with narrowing of lumen seen in high power.",
"image_path": "r7OA0Trj5hQ_image_febb4bba-96f0-4103-8059-ff8932c75cdf.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Severe dysplasia', 'Thick and thin blood vessels', 'Thick vessel wall', 'Narrowing of lumen', 'Vein and artery identification', 'No internal elastic lamina']",
"noisy_text": " And in the resection, you see like a heavy malformation, isn't it? Thick and thin blood vessels of varying sizes are seen. In high power, you can see very thick vessel wall with the narrowing of the lumen, whereas here, it is relatively preserved. So you want to know whether it is a vein or artery. Please believe me, this is a vein, and this is an artery. And that is proved by the elastic tissue strain. These are all pictures from Dr. Gonzalez's Twitter. And you can see here, there is no internal elastic lamina, whereas here,",
"corrected_text": " And in the resection, you see like a heavy malformation, isn't it? Thick and thin blood vessels of varying sizes are seen. In high power, you can see very thick vessel wall with the narrowing of the lumen, whereas here, it is relatively preserved. So you want to know whether it is a vein or artery. Please believe me, this is a vein, and this is an artery. And that is proved by the elastic tissue strain. These are all pictures from Dr. Gonzalez's Twitter. And you can see here, there is no internal elastic lamina, whereas here,",
"med_umls_ids": "[[{'entity': 'Severe', 'concept_id': 'C0205082', 'confidence': 1.0}, {'entity': 'resection', 'concept_id': 'C0015252', 'confidence': 1.0}], [{'entity': 'Thick', 'concept_id': 'C1280412', 'confidence': 1.0}, {'entity': 'thin', 'concept_id': 'C0205168', 'confidence': 1.0}, {'entity': 'sizes', 'concept_id': 'C0456389', 'confidence': 1.0}], [{'entity': 'Thick vessel wall', 'concept_id': 'C1180033', 'confidence': 0.6420797109603882}, {'entity': 'narrowing', 'concept_id': 'C0332463', 'confidence': 1.0}, {'entity': 'lumen', 'concept_id': 'C0524461', 'confidence': 0.9999998807907104}, {'entity': 'power', 'concept_id': 'C0032863', 'confidence': 1.0}], [{'entity': 'Identification', 'concept_id': 'C0020792', 'confidence': 1.0}, {'entity': 'vein', 'concept_id': 'C0042449', 'confidence': 1.0}, {'entity': 'artery', 'concept_id': 'C0003842', 'confidence': 1.0}, {'entity': 'elastic tissue', 'concept_id': 'C0013762', 'confidence': 1.0}, {'entity': 'strain', 'concept_id': 'C0080194', 'confidence': 1.0}], [{'entity': 'image', 'concept_id': 'C1696103', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_233",
"caption_rating": "7"
},
{
"": "1005334",
"caption": "The narrator is discussing pigmented Bowen\u2019s disease, which can resemble other benign skin conditions but must be checked for orderly maturation to differentiate it from squamous cell carcinoma.",
"image_path": "8S4LeiO6Bbk_image_50f66f5c-c802-4748-adb4-a891c25cb444.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['pigmented Bowen\u2019s disease', 'pigmented Bowen\u2019s disease', 'psoriasis form dermatitis', 'inflamed pigmented seborrheic keratosis', 'squamous cell carcinoma', 'interface dermatitis']",
"noisy_text": " of pigmented Bowen's disease or pigmented squamous cell carcinoma. One could see similar changes in lesions too of boenoid papillosis and if this was one of many or a few papules on the genitalia one would have to keep boenoid papillosis and the differential as well here but this is one of these lesions that kind of is a fooler because it has a benign silhouette, resembles a psoriasis form dermatitis or even an inflamed pigmented seborrheic keratosis but it always behooves you to go down and check to make sure that you've got orderly maturation because architecturally Bowen's disease can resemble a benign keratosis. So, pigmented Bowen's disease in this case. Moving on to slide number eight. Slide number eight is the first of two interface dermatitis that we're",
"corrected_text": " of pigmented Bowen's disease or pigmented squamous cell carcinoma. One could see similar changes in lesions too of bowenoid papulosis and if this was one of many or a few papules on the genitalia one would have to keep bowenoid papulosis and the differential as well here but this is one of these lesions that kind of is a fooler because it has a benign silhouette, resembles a psoriasis form dermatitis or even an inflamed pigmented seborrheic keratosis but it always behooves you to go down and check to make sure that you've got orderly maturation because architecturally squamous cell carcinoma's disease can resemble a benign keratosis. So, pigmented Bowen's disease in this case. Moving on to slide number eight. Slide number eight is the first of two interface dermatitis that we're",
"med_umls_ids": "[[{'entity': 'narrator', 'concept_id': 'C1135957', 'confidence': 0.7711340188980103}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'Bowen\u2019s disease', 'concept_id': 'C0006079', 'confidence': 0.9730859994888306}, {'entity': 'benign', 'concept_id': 'C0205183', 'confidence': 1.0}, {'entity': 'maturation', 'concept_id': 'C0678723', 'confidence': 1.0}, {'entity': 'differentiate', 'concept_id': 'C0205615', 'confidence': 0.9999998807907104}, {'entity': 'squamous cell carcinoma', 'concept_id': 'C0007137', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_234",
"caption_rating": "7"
},
{
"": "1008176",
"caption": "Membranous lipodystrophy seen at the periphery of the fat microcysts.",
"image_path": "hoV-JkD6Wb0_image_4a527a05-1434-4bf5-a26a-6d9a6454057f.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['Large fat microcysts', 'Membranous lipodystrophy at the periphery of the fat microcysts', 'Arabesque-type fibular material at the periphery of the fat microcysts', 'Remnant cell walls of adipocytes at the periphery of the fat microcysts', 'Large fat microcysts', 'Membranous lipodystrophy at the periphery of the fat microcysts', 'Arabesque-type fibular material at the periphery of the fat microcysts', 'Remnant cell walls of adipocytes at the periphery of the fat microcysts']",
"noisy_text": " inflammation. There aren't many viable adipocytes left here. A lot of the adipocytes have kind of ruptured and fused, and so we've got these large fat microcysts, and if we look at the periphery of the fat microcyst, we've got this lipomembranous change, this kind of arabesque-type fibular material out at the periphery, which basically represents coalescence of remnant cell walls of adipocytes. In addition, within the surrounding tissue, there's a little bit of fibrosis. There are a few lipophages and a very sparse infiltrative",
"corrected_text": " inflammation. There aren't many viable adipocytes left here. A lot of the adipocytes have kind of ruptured and fused, and so we've got these large fat microcysts, and if we look at the periphery of the fat microcyst, we've got this lipomembranous change, this kind of arabesque-type fibular material out at the periphery, which basically represents coalescence of remnant cell walls of adipocytes. In addition, within the surrounding tissue, there's a little bit of fibrosis. There are a few lipophages and a very sparse infiltrative",
"med_umls_ids": "[[{'entity': 'Inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}], [{'entity': 'adipocytes', 'concept_id': 'C0206131', 'confidence': 1.0}, {'entity': 'left', 'concept_id': 'C0205091', 'confidence': 1.0}], [{'entity': 'fat microcysts', 'concept_id': 'C1513269', 'confidence': 0.871767520904541}], [{'entity': 'Membranous lipodystrophy', 'concept_id': 'C0406599', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'fat microcysts', 'concept_id': 'C1513269', 'confidence': 0.871767520904541}], [{'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'fat microcysts', 'concept_id': 'C1513269', 'confidence': 0.871767520904541}], [{'entity': 'Coalescence', 'concept_id': 'C4727092', 'confidence': 0.8749340176582336}, {'entity': 'remnant', 'concept_id': 'C3272697', 'confidence': 1.0}, {'entity': 'cell walls', 'concept_id': 'C0007623', 'confidence': 1.0}, {'entity': 'adipocytes', 'concept_id': 'C0206131', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'fat microcysts', 'concept_id': 'C1513269', 'confidence': 0.871767520904541}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_235",
"caption_rating": "8"
},
{
"": "1005623",
"caption": "The glomerulus is compressed and surrounded by a crescent, which can be classified as either a fibrous crescent or a fibrous cellular crescent. The sample shown has both types of crescents present.",
"image_path": "WhnEXkBN4D8_image_855adbc7-421b-462d-ab24-4af597a7fa2b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Renal', 'Hematopathology', 'Soft tissue']",
"roi_text": "['Compressed glomerulus surrounded by a crescent, with both fibrous and cellular components.']",
"noisy_text": " Look at this glomeruli. This is the capsule. Everything else is compressed. So can I call this a beautiful crescent? Yes. So as a pathologist, when you compare the crescent, you have to say whether it's a fibrous crescent or a fibrous cellular crescent because that also makes sense here. Here, I do have half of them. It's more of acellular area fibrous and here I do have cellularity as well. Look at this. My glomerulus is here. It's only in one pole. Rest everything is replaced by cellular crescent, right? Because like",
"corrected_text": " Look at this glomerulus. This is the capsule. Everything else is compressed. So can I call this a beautiful crescent? Yes. So as a pathologist, when you compare the crescent, you have to say whether it's a fibrous crescent or a fibrous cellular crescent because that also makes sense here. Here, I do have half of them. It's more of fibrous crescent and here I do have cellularity as well. Look at this. My glomerulus is here. It's only in one pole. Rest everything is replaced by cellular crescent, right? Because like",
"med_umls_ids": "[[{'entity': 'glomerulus', 'concept_id': 'C0022663', 'confidence': 1.0}, {'entity': 'compressed', 'concept_id': 'C0332260', 'confidence': 1.0}, {'entity': 'surrounded', 'concept_id': 'C1282914', 'confidence': 1.0}, {'entity': 'crescent', 'concept_id': 'C0444628', 'confidence': 1.0}, {'entity': 'fibrous crescent', 'concept_id': 'C0439709', 'confidence': 0.6849074363708496}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}, {'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'crescents', 'concept_id': 'C0444628', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_236",
"caption_rating": "8"
},
{
"": "1008744",
"caption": "Epithelial and pseudoepithelial metaplasia and hyperplasia are present in the lesion.",
"image_path": "hoV-JkD6Wb0_image_f1801b51-f6e9-4f7c-903c-1448201290c2.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['epithelial metaplasia', 'epithelial hyperplasia', 'nodular infiltrate', 'clear spaces', 'lymphocytes', 'plasma cells', 'epithelial metaplasia', 'epithelial hyperplasia', 'nodular infiltrate', 'clear spaces', 'lymphocytes', 'plasma cells']",
"noisy_text": " from this lesion that hopefully you had a chance to look at, quadricected shade biopsy. And one can see quite a bit of epithelial, pseudoepithelial metacyproplasia, epithelial hyperplasia. I think I'm going to flip the slide and look at the top piece in the dermis. And one can see we have a nodular infiltrate in the dermis, lots and lots of clear spaces centrally, and then some darker staining cells out at the periphery. And out at the periphery, we have a lot of lymphocytes and several scattered plasma cells. And if we look at the more clear staining areas, we can",
"corrected_text": " from this lesion that hopefully you had a chance to look at, excisional biopsy. And one can see quite a bit of epithelial, pseudoepithelial metaplasia, epithelial hyperplasia. I think I'm going to flip the slide and look at the top piece in the dermis. And one can see we have a nodular infiltrate in the dermis, lots and lots of clear spaces centrally, and then some darker staining cells out at the periphery. And out at the periphery, we have a lot of lymphocytes and several scattered plasma cells. And if we look at the more clear staining areas, we can",
"med_umls_ids": "[[{'entity': 'Epithelial', 'concept_id': 'C0221908', 'confidence': 1.0}, {'entity': 'pseudoepithelial metaplasia', 'concept_id': 'C1317977', 'confidence': 0.7813463807106018}, {'entity': 'hyperplasia', 'concept_id': 'C0020507', 'confidence': 1.0}, {'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}], [{'entity': 'Nodular infiltrate', 'concept_id': 'C0241130', 'confidence': 0.840809166431427}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'centrally', 'concept_id': 'C0205099', 'confidence': 0.7070305943489075}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'scattered', 'concept_id': 'C0439742', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_237",
"caption_rating": "8"
},
{
"": "1004547",
"caption": "The lesion is a localized, circumscribed area without granulomatous abnormalities or dyskeratotic keratinocytes, ruling out porokeratosis.",
"image_path": "udoW6VSqsm4_image_e29262c3-0d70-4b0a-a6c2-41a0befaa599.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['loss of the cornified layer']",
"noisy_text": " And so, the other things we kind of talked about are a bit differential, but next slide. Nothing else really will give you this kind of localized circumscribed area like this, so it's not poro. That would have a coronal lamella with granulocidal abnormalities and dyskeratonic keratinocytes. We don't see that here, so this is just a loss of the coronified layer. And there's one other condition where you kind of get, where are some other little clonal, you know, somatic mutations that you can get abnormalities in the epithelium that occur just in localized areas. That's not like loss of the coronified layer. We'll put a couple of other diseases where you see just local areas that are abnormal, and you get normal skin to the side. So, poro is one. We'll put",
"corrected_text": " And so, the other things we kind of talked about are a bit differential, but next slide. Nothing else really will give you this kind of localized circumscribed area like this, so it's not poro. That would have a coronal lamella with granulomatous abnormalities and dyskeratotic keratinocytes. We don't see that here, so this is just a loss of the cornified layer. And there's one other condition where you kind of get, where are some other little clonal, you know, somatic mutations that you can get abnormalities in the epithelium that occur just in localized areas. That's not like loss of the cornified layer. We'll put a couple of other diseases where you see just local areas that are abnormal, and you get normal skin to the side. So, poro is one. We'll put",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'localized', 'concept_id': 'C0392752', 'confidence': 1.0}, {'entity': 'circumscribed area', 'concept_id': 'C1282914', 'confidence': 0.9260231852531433}, {'entity': 'granulomatous abnormalities', 'concept_id': 'C0439667', 'confidence': 0.7099277377128601}, {'entity': 'dyskeratotic keratinocytes', 'concept_id': 'C1512099', 'confidence': 0.9701507091522217}, {'entity': 'porokeratosis', 'concept_id': 'C0162839', 'confidence': 1.0}], [{'entity': 'loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'cornified layer', 'concept_id': 'C3554359', 'confidence': 0.8562335968017578}], [{'entity': 'conditions', 'concept_id': 'C0012634', 'confidence': 0.8556983470916748}, {'entity': 'localized', 'concept_id': 'C0392752', 'confidence': 1.0}, {'entity': 'abnormality', 'concept_id': 'C1704258', 'confidence': 1.0}, {'entity': 'somatic mutations', 'concept_id': 'C0544886', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_238",
"caption_rating": "9"
},
{
"": "1007537",
"caption": "Description of translocation sarcoma in myxoid liposarcoma, with FUS-DDIT3 being the most common translocation.",
"image_path": "pBR26SS0FX8_image_c791c0e5-57ad-4c79-8493-6dacad209618.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Hematopathology', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " in regular conventional myxoid liposarcoma. You see these little cells, they are also very bland. Again, a translocation sarcoma, right? So these cells have a translocation. FUSDDIT3 used to be called FUSCHOP, was the most common one. Occasionally a subset of them like 5% or so will have EWSR1, Ewing's gene rearranged with DDIT3. And so if you haven't learned yet that a lot of times if there's a rearrangement of EWSR1 with some other gene, eventually someone's gonna find cases that have FUS rearranged with that same gene and vice versa because FUS and EWSR1 are similar genes, a kind of same gene family, which again, this is way over my head, I'm not a molecular pathologist. But the point is they often swap out for one another. So that's",
"corrected_text": " in regular conventional myxoid liposarcoma. You see these little cells, they are also very bland. Again, a translocation sarcoma, right? So these cells have a translocation. FUS-DDIT3 used to be called FUSCHOP, was the most common one. Occasionally a subset of them like 5% or so will have EWSR1, Ewing's gene rearranged with DDIT3. And so if you haven't learned yet that a lot of times if there's a rearrangement of EWSR1 with some other gene, eventually someone's gonna find cases that have FUS rearranged with that same gene and vice versa because FUS and EWSR1 are similar genes, a kind of same gene family, which again, this is way over my head, I'm not a molecular pathologist. But the point is they often swap out for one another. So that's",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'translocation sarcoma', 'concept_id': 'C0040715', 'confidence': 0.7855618000030518}, {'entity': 'myxoid liposarcoma', 'concept_id': 'C0206634', 'confidence': 1.0}, {'entity': 'FUS-DDIT3', 'concept_id': 'C1852061', 'confidence': 0.894819438457489}, {'entity': 'translocation', 'concept_id': 'C0040715', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_239",
"caption_rating": "9"
},
{
"": "1004749",
"caption": "Presence of irregularly sized and shaped glands with variation in distribution indicating chronicity.",
"image_path": "r7OA0Trj5hQ_image_5f54ce10-dac2-4f67-9d3f-86fec3c42d30.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Gastroesophageal junction with irregularly sized and shaped glands and variation in distribution.', 'Gastroesophageal junction with irregularly sized and shaped glands and variation in distribution.']",
"noisy_text": " metaplasia or dysplasia, either low-grade or high-grade. So this is a squamous epithelium. This is a gastric cardiac type of epithelium. So this is a gastroesophageal junction. Here you can see nice bifitting. And see the glands are not uniformly distributed. Variation in size. Some glands are small, some glands are large. And these glands are not branching normally, but you can see a nice bifitting. So these are all features of chronicity. Irregular size, shape, distribution means chronicity. Please remember, presence of lymphocytes and plasma cells is not a",
"corrected_text": " metaplasia or dysplasia, either low-grade or high-grade. So this is a squamous epithelium. This is a gastric cardiac type of epithelium. So this is a gastroesophageal junction. Here you can see nice bifitting. And see the glands are not uniformly distributed. Variation in size. Some glands are small, some glands are large. And these glands are not branching normally, but you can see a nice bifitting. So these are all features of chronicity. Irregular size, shape, distribution means chronicity. Please remember, presence of lymphocytes and plasma cells is not a",
"med_umls_ids": "[[{'entity': 'Identification', 'concept_id': 'C0020792', 'confidence': 1.0}, {'entity': 'squamous epithelium', 'concept_id': 'C0221909', 'confidence': 1.0}, {'entity': 'gastric cardiac type', 'concept_id': 'C0524600', 'confidence': 0.7429378628730774}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'gastroesophageal junction', 'concept_id': 'C0014871', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'irregularly', 'concept_id': 'C0425589', 'confidence': 0.905201256275177}, {'entity': 'sized', 'concept_id': 'C0600244', 'confidence': 0.8308623433113098}, {'entity': 'shaped glands', 'concept_id': 'C0332479', 'confidence': 0.7275685667991638}, {'entity': 'variation', 'concept_id': 'C0205419', 'confidence': 1.0}, {'entity': 'distribution', 'concept_id': 'C0037775', 'confidence': 1.0}, {'entity': 'chronicity', 'concept_id': 'C0547045', 'confidence': 1.0}], [{'entity': 'Importance', 'concept_id': 'C4086513', 'confidence': 0.96006178855896}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_240",
"caption_rating": "9"
},
{
"": "1006835",
"caption": "Presence of H. pylori in the luminal area or lumen of the stomach.",
"image_path": "r7OA0Trj5hQ_image_106ad5eb-cc4c-4670-b26e-1ee0397de984.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Neutrophils on the epithelium indicating active inflammation', 'H. pylori in the luminal area or lumen', 'Goblet cells in the surface epithelium.', 'H. pylori in the luminal area or lumen']",
"noisy_text": " this is equivalent to cryptitis in the colon. In the stomach, we call it pit, so I don't want to call it pititis. It doesn't sound very great, but you can see the neutrophils sitting on the epithelium. So this is an active inflammation. Here, now we are coming to cytology. You see in the intra-luminal area or in the lumen, you see a lot of comma-shaped rods sitting on the epithelium, not going into the epithelium. So these are all the H. pylori in the oil immersion. Here, the surface epithelium shows goblet cells, and these are all biopsies",
"corrected_text": " this is equivalent to cryptitis in the colon. In the stomach, we call it pit, so I don't want to call it pititis. It doesn't sound very great, but you can see the neutrophils sitting on the epithelium. So this is an active inflammation. Here, now we are coming to cytology. You see in the luminal area or in the lumen, you see a lot of comma-shaped rods sitting on the epithelium, not going into the epithelium. So these are all the H. pylori in the oil immersion. Here, the surface epithelium shows goblet cells, and these are all biopsies",
"med_umls_ids": "[[{'entity': 'Active inflammation', 'concept_id': 'C0333361', 'confidence': 1.0}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'H. pylori', 'concept_id': 'C0079488', 'confidence': 1.0}, {'entity': 'luminal area', 'concept_id': 'C0524462', 'confidence': 0.7778207659721375}, {'entity': 'lumen', 'concept_id': 'C0524461', 'confidence': 0.9999998807907104}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}], [{'entity': 'Surface epithelium', 'concept_id': 'C1182809', 'confidence': 1.0}, {'entity': 'goblet cells', 'concept_id': 'C0506994', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_241",
"caption_rating": "8"
},
{
"": "1007222",
"caption": "Combined melanocytic nevus with features of both a common or benign nevus and a blue nevus.",
"image_path": "8S4LeiO6Bbk_image_38e60f68-290e-4146-add5-b6c842bcc610.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['dendritic', 'spindle-shaped', 'heavily pigmented melanophages', 'dendritic', 'spindle-shaped', 'intersecting vessels', 'combined melanocytic nevus', 'blue nevus']",
"noisy_text": " pairs. In the central portion of the specimen, you can see that the dermis is a little more sclerotic. And we've got the presence of separately heavily pigmented melanovagias. And then if we look at our top piece of tissue, again, we have the more banal appearing melanocytes out of the periphery. And centrally, we've got embedded within a sclerotic stroma a second distinct morphologic population of melanocytes. Some of these are dendritic, others have spindled or fusiform-shaped nuclei. They're arranged in short, intersecting vascals. And in between the dendritic and spindled melanocytes, we have very heavily pigmented melanovagias, all set in a sclerotic stroma. So basically, we have here a combined melanocytic nevus, one that has features of both a common or banal nevus and a blue nevus. And this",
"corrected_text": " pairs. In the central portion of the specimen, you can see that the dermis is a little more sclerotic. And we've got the presence of separately heavily pigmented melanovagias. And then if we look at our top piece of tissue, again, we have the more banal appearing melanocytes out of the periphery. And centrally, we've got embedded within a sclerotic stroma a second distinct morphologic population of melanocytes. Some of these are dendritic, others have spindle-shaped or fusiform-shaped cells. They're arranged in short, intersecting vessels. And in between the dendritic and spindle-shaped melanocytes, we have very heavily pigmented melanovagias, all set in a sclerotic stroma. So basically, we have here a combined melanocytic nevus, one that has features of both a common or banal nevus and a blue nevus. And this",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'heavily', 'concept_id': 'C0337678', 'confidence': 0.6902515292167664}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'melanophages', 'concept_id': 'C3280463', 'confidence': 0.9375340938568115}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}], [{'entity': 'morphologic populations', 'concept_id': 'C0032659', 'confidence': 0.6858205199241638}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'dendritic', 'concept_id': 'C0011305', 'confidence': 1.0}, {'entity': 'spindle-shaped', 'concept_id': 'C4230397', 'confidence': 0.9035798907279968}, {'entity': 'fusiform-shaped', 'concept_id': 'C0332493', 'confidence': 0.6468937397003174}], [{'entity': 'Arranged', 'concept_id': 'C1546854', 'confidence': 1.0}, {'entity': 'short', 'concept_id': 'C1282927', 'confidence': 1.0}, {'entity': 'intersecting vessels', 'concept_id': 'C0005847', 'confidence': 0.7007781863212585}], [{'entity': 'Combined', 'concept_id': 'C0205195', 'confidence': 1.0}, {'entity': 'melanocytic nevus', 'concept_id': 'C0027962', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'benign nevus', 'concept_id': 'C1456781', 'confidence': 1.0}, {'entity': 'blue nevus', 'concept_id': 'C0206736', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_242",
"caption_rating": "9"
},
{
"": "1008352",
"caption": "Presence of heavily pigmented melanophages in the dermis.",
"image_path": "8S4LeiO6Bbk_image_4ef5f72f-08fe-425e-b264-7a8376fe57f9.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['heavily pigmented melanophages', 'dendritic', 'spindle-shaped', 'intersecting vessels', 'combined melanocytic nevus', 'blue nevus', 'heavily pigmented melanophages', 'dendritic', 'spindle-shaped', 'intersecting vessels', 'combined melanocytic nevus', 'blue nevus']",
"noisy_text": " pairs. In the central portion of the specimen, you can see that the dermis is a little more sclerotic. And we've got the presence of separately heavily pigmented melanovagias. And then if we look at our top piece of tissue, again, we have the more banal appearing melanocytes out of the periphery. And centrally, we've got embedded within a sclerotic stroma a second distinct morphologic population of melanocytes. Some of these are dendritic, others have spindled or fusiform-shaped nuclei. They're arranged in short, intersecting vascals. And in between the dendritic and spindled melanocytes, we have very heavily pigmented melanovagias, all set in a sclerotic stroma. So basically, we have here a combined melanocytic nevus, one that has features of both a common or banal nevus and a blue nevus. And this",
"corrected_text": " pairs. In the central portion of the specimen, you can see that the dermis is a little more sclerotic. And we've got the presence of separately heavily pigmented melanovagias. And then if we look at our top piece of tissue, again, we have the more banal appearing melanocytes out of the periphery. And centrally, we've got embedded within a sclerotic stroma a second distinct morphologic population of melanocytes. Some of these are dendritic, others have spindle-shaped or fusiform-shaped cells. They're arranged in short, intersecting vessels. And in between the dendritic and spindle-shaped melanocytes, we have very heavily pigmented melanovagias, all set in a sclerotic stroma. So basically, we have here a combined melanocytic nevus, one that has features of both a common or banal nevus and a blue nevus. And this",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'heavily', 'concept_id': 'C0337678', 'confidence': 0.6902515292167664}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'melanophages', 'concept_id': 'C3280463', 'confidence': 0.9375340938568115}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}], [{'entity': 'morphologic populations', 'concept_id': 'C0032659', 'confidence': 0.6858205199241638}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'dendritic', 'concept_id': 'C0011305', 'confidence': 1.0}, {'entity': 'spindle-shaped', 'concept_id': 'C4230397', 'confidence': 0.9035798907279968}, {'entity': 'fusiform-shaped', 'concept_id': 'C0332493', 'confidence': 0.6468937397003174}], [{'entity': 'Arranged', 'concept_id': 'C1546854', 'confidence': 1.0}, {'entity': 'short', 'concept_id': 'C1282927', 'confidence': 1.0}, {'entity': 'intersecting vessels', 'concept_id': 'C0005847', 'confidence': 0.7007781863212585}], [{'entity': 'Combined', 'concept_id': 'C0205195', 'confidence': 1.0}, {'entity': 'melanocytic nevus', 'concept_id': 'C0027962', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'benign nevus', 'concept_id': 'C1456781', 'confidence': 1.0}, {'entity': 'blue nevus', 'concept_id': 'C0206736', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_243",
"caption_rating": "9"
},
{
"": "1004494",
"caption": "Nodules on acral skin can be caused by leukocytoclastic vasculitis that can end up with these nodular lesions.",
"image_path": "udoW6VSqsm4_image_aa82a88b-0c10-40be-a90f-a118b2d6c185.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " You notice this is on acral skin. There are often nodules in that area, and they can start off as palpable purpura in some cases. So, it's like, you know, regular leukocytoplastic vasculitis that can end up with these nodular lesions. Next slide. What is the histologic identical twin of this process? The granulomyphial. Yes, excellent. Granulomyphial looks very, very similar to this on the microscope. Obviously, clinically, it's not like this. It's on the face. It's on the pseudolymphoma. Next slide. So, this is a type of chronic vasculitis that ends up forming these fibrotic nodules. It's an interesting condition, and it is thought to be associated with other conditions. So, you want to make sure that you don't just, next case. A lot of times, these things can give you cholesterol clefts. One of the old names for this years ago used to be extracellular cholesterolosis, and it would give you these, all these neutrophils would gradually degranulate, if you will. The neutrophil products would have lipid in them, and you'd get these cholesterol clefts that would look kind of yellowish. Now, what are a couple other clinical diseases where you can see nodules around joints? You know, like, gout, RA, OE. Good. Gout, RA. There's",
"corrected_text": " You notice this is on acral skin. There are often nodules in that area, and they can start off as palpable purpura in some cases. So, it's like, you know, leukocytoclastic vasculitis that can end up with these nodular lesions. Next slide. What is the histologic identical twin of this process? The granuloma faciale. Yes, excellent. granuloma faciale looks very, very similar to this on the microscope. Obviously, clinically, it's not like this. It's on the face. It's on the pseudolymphoma. Next slide. So, this is a type of chronic vasculitis that ends up forming these fibrotic nodules. It's an interesting condition, and it is thought to be associated with other conditions. So, you want to make sure that you don't just, next case. A lot of times, these things can give you cholesterol clefts. One of the old names for this years ago used to be extracellular cholesterolosis, and it would give you these, all these neutrophils would gradually degranulate, if you will. The neutrophil products would have lipid in them, and you'd get these cholesterol clefts that would look kind of yellowish. Now, what are a couple other clinical diseases where you can see nodules around joints? You know, like, gout, RA, OE. Good. Gout, RA. There's",
"med_umls_ids": "[[{'entity': 'Nodules', 'concept_id': 'C0028259', 'confidence': 1.0}, {'entity': 'acral skin', 'concept_id': 'C0444099', 'confidence': 0.7122198939323425}, {'entity': 'leukocytoclastic vasculitis', 'concept_id': 'C0151436', 'confidence': 1.0}, {'entity': 'nodular', 'concept_id': 'C0205297', 'confidence': 1.0}, {'entity': 'lesions', 'concept_id': 'C0221198', 'confidence': 1.0}], [{'entity': 'Granuloma faciale', 'concept_id': 'C0239495', 'confidence': 1.0}, {'entity': 'histologic', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'identical', 'concept_id': 'C0205280', 'confidence': 1.0}, {'entity': 'twin', 'concept_id': 'C0041427', 'confidence': 0.9999999403953552}, {'entity': 'process', 'concept_id': 'C1184743', 'confidence': 1.0}], [{'entity': 'Granuloma faciale', 'concept_id': 'C0239495', 'confidence': 1.0}, {'entity': 'leukocytoclastic vasculitis', 'concept_id': 'C0151436', 'confidence': 1.0}, {'entity': 'microscope', 'concept_id': 'C0181839', 'confidence': 1.0}], [{'entity': 'Chronic vasculitis', 'concept_id': 'C0042384', 'confidence': 0.7992802858352661}, {'entity': 'fibrotic nodules', 'concept_id': 'C0332561', 'confidence': 0.8351579308509827}], [{'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'associated with', 'concept_id': 'C0332281', 'confidence': 1.0}, {'entity': 'conditions', 'concept_id': 'C0012634', 'confidence': 0.8556983470916748}], [{'entity': 'Extracellular cholesterolosis', 'concept_id': 'C2973528', 'confidence': 0.9169934391975403}, {'entity': 'cholesterol clefts', 'concept_id': 'C3686582', 'confidence': 0.9999999403953552}, {'entity': 'yellowish nodules', 'concept_id': 'C1867455', 'confidence': 0.8135299682617188}], [{'entity': 'Nodules', 'concept_id': 'C0028259', 'confidence': 1.0}, {'entity': 'joints', 'concept_id': 'C0022417', 'confidence': 1.0}, {'entity': 'gout', 'concept_id': 'C0018099', 'confidence': 1.0}, {'entity': 'RA', 'concept_id': 'C0002893', 'confidence': 1.0}, {'entity': 'OE', 'concept_id': 'C1551089', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_244",
"caption_rating": "8"
},
{
"": "1004774",
"caption": "The tumor is a variation of low-grade fibromyxoid sarcoma, which can be confused with the neuroblastoma-like variant of schwannoma.",
"image_path": "QDb68_G1HR4_image_7cea0913-e476-4f9a-8b1b-a61bc5b81a7b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Big collagen rich rosettes', 'Prominent round cell appearance around the edge of the rim of the nodules', 'Small round blue cells of a neuroblastoma', 'Big collagen rich rosettes', 'Prominent round cell appearance around the edge of the rim of the nodules', 'Small round blue cells of a neuroblastoma']",
"noisy_text": " It has also big collagen rich rosettes like this but it has a much more prominent round cell appearance around the edge of the rim of the nodules are very like small round blue cell almost look a little bit like the small round blue cells of a neuroblastoma which is why it's named that way but I've definitely seen pathologists have trouble telling those two apart telling a hyalinizing spindle cell tumor with giant rosettes. This tumor we're looking at here a variation of low-grade fibromyxoid sarcoma I've seen people get that confused with the neuroblastoma-like variant of schwannoma and the difference is important because the schwannoma is even though the name sounds kind of scary is actually benign it has a small round blue cell appearance but it's totally benign variation of schwannoma. S100 should easily solve that problem because S100 would be negative here in low-grade fibromyxoid sarcoma and",
"corrected_text": " It has also big collagen rich rosettes like this but it has a much more prominent round cell appearance around the edge of the rim of the nodules are very like small round blue cell almost look a little bit like the small round blue cells of a neuroblastoma which is why it's named that way but I've definitely seen pathologists have trouble telling those two apart telling a hyalinizing spindle cell tumor with giant rosettes. This tumor we're looking at here a variation of low-grade fibromyxoid sarcoma I've seen people get that confused with the neuroblastoma-like variant of schwannoma and the difference is important because the schwannoma is even though the name sounds kind of scary is actually benign it has a small round blue cell appearance but it's totally benign variation of schwannoma. S100 should easily solve that problem because S100 would be negative here in low-grade fibromyxoid sarcoma and",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'rosettes', 'concept_id': 'C0035863', 'confidence': 0.8847858905792236}, {'entity': 'round cell', 'concept_id': 'C0487470', 'confidence': 1.0}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'edge', 'concept_id': 'C0205154', 'confidence': 1.0}, {'entity': 'rim', 'concept_id': 'C1308727', 'confidence': 1.0}, {'entity': 'nodules', 'concept_id': 'C0028259', 'confidence': 1.0}, {'entity': 'neuroblastoma', 'concept_id': 'C0027819', 'confidence': 1.0}], [{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'variation', 'concept_id': 'C0205419', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'neuroblastoma-like variant of', 'concept_id': 'C1419295', 'confidence': 0.6589864492416382}, {'entity': 'schwannoma', 'concept_id': 'C0027809', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_245",
"caption_rating": "9"
},
{
"": "1006628",
"caption": "Chronicity can cause architectural distortion in addition to nonspecific findings.",
"image_path": "sDFjOtMAYrk_image_e0850284-dc39-471f-9cff-c2943a16ca3f.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "[]",
"noisy_text": " cytosis that includes some eosinophils. So, the other trich I like to use, and I heard this from Dr. Appelman one time when he was lecturing, and he described crypt architecture in cases with inflammatory bowel disease, you no longer have that nice organized test tubes in a rack kind of architecture. The glands start to look like anything they want to look like. Rabbits, monkeys, the face of Jesus, whatever, except for test tubes on a rack. And the other thing is, sometimes you'll see them instead of growing down, they'll grow sideways. So, that's very apparent, very abnormal. So, I would say this is great evidence of chronicity, good architectural distortion. What other features besides architecture can you see in cases where there's some chronicity, albeit nonspecific findings? I mean, nothing is specific in chronic inflammatory colonic pathology,",
"corrected_text": " cytosis that includes some eosinophils. So, the other trich I like to use, and I heard this from Dr. Appelman one time when he was lecturing, and he described crypt architecture in cases with inflammatory bowel disease, you no longer have that nice organized tubular architecture. The glands start to look like anything they want to look like. Rabbits, monkeys, the face of Jesus, whatever, except for test tubes on a rack. And the other thing is, sometimes you'll see them instead of growing down, they'll grow sideways. So, that's very apparent, very abnormal. So, I would say this is great evidence of chronicity, good architectural distortion. What other features besides architecture can you see in cases where there's some chronicity, albeit nonspecific findings? I mean, nothing is specific in chronic inflammatory colonic pathology,",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'cytosis', 'concept_id': 'C0010843', 'confidence': 0.7890887260437012}], [{'entity': 'Inflammatory bowel disease', 'concept_id': 'C0021390', 'confidence': 1.0}, {'entity': 'loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'tubular', 'concept_id': 'C0151747', 'confidence': 1.0}, {'entity': 'architecture', 'concept_id': 'C0003737', 'confidence': 1.0}, {'entity': 'abnormal', 'concept_id': 'C0205161', 'confidence': 1.0}, {'entity': 'growth', 'concept_id': 'C0018270', 'confidence': 1.0}], [{'entity': 'Chronicity', 'concept_id': 'C0547045', 'confidence': 1.0}, {'entity': 'architectural distortion', 'concept_id': 'C2826609', 'confidence': 1.0}, {'entity': 'nonspecific', 'concept_id': 'C0750540', 'confidence': 1.0}, {'entity': 'findings', 'concept_id': 'C2607943', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_246",
"caption_rating": "8"
},
{
"": "1008980",
"caption": "Cribriform glands at the edge of a core are usually high-grade tumors.",
"image_path": "iklRyY1nBIE_image_544693de-c787-4ed3-a400-43ea5365d478.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['intraductal carcinoma', 'cribriform glands', 'basal cells']",
"noisy_text": " And I'll demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues, it's very important to make that point clear. So this is the corresponding to the case I showed you. So let me just show you a couple more examples of introductal carcinoma of the prostate. So this case, this one looks a little different. You don't have, I mean, looking at the HNE, you may assume all this is invasive. But you'll probably be surprised when you see the corresponding pain cocktail. What you can see here are cribriform glands. Again, it's a busy, busy core, lots of glands. And when you see tumor cells or glands at the edge of a core, at the edge of a core like this, that's usually bats. And usually high-grade tumors that do that. But when you see what we're seeing here, a lot of cribriform glands. And if you go a bit closer, you can see a hint of basal cells around most of them. So we'll",
"corrected_text": " And I'demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues, it's very important to make that point clear. So this is the corresponding to the case I showed you. So let me just show you a couple more examples of introductal carcinoma of the prostate. So this case, this one looks a little different. You don't have, I mean, looking at the HNE, you may assume all this is invasive. But you'll probably be surprised when you see the corresponding pain cocktail. What you can see here are cribriform glands. Again, it's a busy, busy core, lots of glands. And when you see tumor cells or glands at the edge of a core, at the edge of a core like this, that's usually bats. And usually high-grade tumors that do that. But when you see what we're seeing here, a lot of cribriform glands. And if you go a bit closer, you can see a hint of basal cells around most of them. So we'll",
"med_umls_ids": "[[{'entity': 'Intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'associated with', 'concept_id': 'C0332281', 'confidence': 1.0}, {'entity': 'invasive cancer', 'concept_id': 'C0677898', 'confidence': 1.0}], [{'entity': 'Cribriform glands', 'concept_id': 'C1285092', 'confidence': 0.6162902116775513}, {'entity': 'edge', 'concept_id': 'C0205154', 'confidence': 1.0}, {'entity': 'core', 'concept_id': 'C0444669', 'confidence': 0.9999999403953552}, {'entity': 'high-grade tumors', 'concept_id': 'C0027651', 'confidence': 0.5436328053474426}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'basal cells', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'cribriform glands', 'concept_id': 'C1285092', 'confidence': 0.6162902116775513}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_247",
"caption_rating": "8"
},
{
"": "1006834",
"caption": "Active inflammation in the stomach, with neutrophils present on the epithelium.",
"image_path": "r7OA0Trj5hQ_image_106ad5eb-cc4c-4670-b26e-1ee0397de984.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Neutrophils on the epithelium indicating active inflammation', 'H. pylori in the luminal area or lumen', 'Goblet cells in the surface epithelium.', 'H. pylori in the luminal area or lumen']",
"noisy_text": " this is equivalent to cryptitis in the colon. In the stomach, we call it pit, so I don't want to call it pititis. It doesn't sound very great, but you can see the neutrophils sitting on the epithelium. So this is an active inflammation. Here, now we are coming to cytology. You see in the intra-luminal area or in the lumen, you see a lot of comma-shaped rods sitting on the epithelium, not going into the epithelium. So these are all the H. pylori in the oil immersion. Here, the surface epithelium shows goblet cells, and these are all biopsies",
"corrected_text": " this is equivalent to cryptitis in the colon. In the stomach, we call it pit, so I don't want to call it pititis. It doesn't sound very great, but you can see the neutrophils sitting on the epithelium. So this is an active inflammation. Here, now we are coming to cytology. You see in the luminal area or in the lumen, you see a lot of comma-shaped rods sitting on the epithelium, not going into the epithelium. So these are all the H. pylori in the oil immersion. Here, the surface epithelium shows goblet cells, and these are all biopsies",
"med_umls_ids": "[[{'entity': 'Active inflammation', 'concept_id': 'C0333361', 'confidence': 1.0}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'H. pylori', 'concept_id': 'C0079488', 'confidence': 1.0}, {'entity': 'luminal area', 'concept_id': 'C0524462', 'confidence': 0.7778207659721375}, {'entity': 'lumen', 'concept_id': 'C0524461', 'confidence': 0.9999998807907104}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}], [{'entity': 'Surface epithelium', 'concept_id': 'C1182809', 'confidence': 1.0}, {'entity': 'goblet cells', 'concept_id': 'C0506994', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_248",
"caption_rating": "8"
},
{
"": "1004765",
"caption": "Involvement around damaged nerves is a common feature of sarcoid granulomatous inflammation.",
"image_path": "udoW6VSqsm4_image_d3b7d20d-bd25-4ede-8f42-4c2f388337bb.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['sarcoid granulomatous inflammation', 'involvement around nerves']",
"noisy_text": " That's the tuberculoid. Yeah, good. The tuberculoid form of leprosy gives you sarcoidal granulomatous inflammation. It's elongated. Very good. That's exactly right. What else can give you sarcoidal granulomatous inflammation? Can I ask a quick question about the sarcoid with the two... The nansins? So, I had a case, I saw a case that looked kind of horizontal, but it was sarcoid. And so, what other ways can you tell? Sometimes it can be difficult, but usually you're going to see involvement around nerves damaged nerves. You're about to get sarcoidal granulomatous inflammation. They always have very high risk inflammatory reactions. They just wipe out the nerves. So, that's helpful. Wasn't",
"corrected_text": " That's the tuberculoid. Yeah, good. The tuberculoid form of leprosy gives you sarcoidal granulomatous inflammation. It's elongated. Very good. That's exactly right. What else can give you sarcoidal granulomatous inflammation? Can I ask a quick question about the sarcoid with the two... The sarcoidosis? So, I had a case, I saw a case that looked kind of horizontal, but it was sarcoid. And so, what other ways can you tell? Sometimes it can be difficult, but usually you're going to see involvement around nerves damaged nerves. You're about to get sarcoidal granulomatous inflammation. They always have very high risk inflammatory reactions. They just wipe out the nerves. So, that's helpful. Wasn't",
"med_umls_ids": "[[{'entity': 'Tuberculoid', 'concept_id': 'C0544783', 'confidence': 0.8459237217903137}, {'entity': 'leprosy', 'concept_id': 'C0023343', 'confidence': 1.0}, {'entity': 'sarcoid', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'granulomatous inflammation', 'concept_id': 'C0553697', 'confidence': 1.0}], [{'entity': 'Involvement', 'concept_id': 'C1314939', 'confidence': 1.0}, {'entity': 'damaged nerves', 'concept_id': 'C3887709', 'confidence': 0.8087002038955688}, {'entity': 'sarcoid', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'granulomatous inflammation', 'concept_id': 'C0553697', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_249",
"caption_rating": "7"
},
{
"": "1007772",
"caption": "Pigmented histiocytes containing hemocyanin are present in the lesion.",
"image_path": "8S4LeiO6Bbk_image_b967e7cf-8e2d-4ad6-9e07-120166272435.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['lipid vacuoles', 'multinucleated histiocytes', 'ringed siderophages', 'pigmented histiocytes', 'hemocyanin', 'lipid vacuoles', 'multinucleated histiocytes', 'ringed siderophages', 'pigmented histiocytes', 'hemocyanin', 'lipid vacuoles', 'multinucleated histiocytes', 'ringed siderophages', 'pigmented histiocytes', 'hemocyanin', 'lipid vacuoles', 'multinucleated histiocytes', 'ringed siderophages', 'pigmented histiocytes', 'hemocyanin']",
"noisy_text": " large histiocytes containing lipid. Some of them are multi-nucleated and some of these are actually ringed siderophages. So we see large multi-nucleated histiocytes with a ring of nuclei and they contain not only lipid vacuoles but hemocentaurant. And these are particularly common in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes as suspected is hemocentaurant. If you notice, it's got kind of that golden brown color. If you had a sub-stage condenser or a fine focus knob, you would see that it's somewhat refractile, but unfortunately, we can't use that particular tool when we're looking at scanned images.",
"corrected_text": " large histiocytes containing lipid. Some of them are multinucleated and some of these are actually ringed siderophages. So we see large multinucleated histiocytes with a ring of nuclei and they contain not only lipid vacuoles but hemosiderin. And these are particularly common in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes as suspected is hemosiderin. If you notice, it's got kind of that golden brown color. If you had a sub-stage condenser or a fine focus knob, you would see that it's somewhat refractile, but unfortunately, we can't use that particular tool when we're looking at scanned images.",
"med_umls_ids": "[[{'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'lipid', 'concept_id': 'C0023779', 'confidence': 1.0}, {'entity': 'multinucleated', 'concept_id': 'C0333740', 'confidence': 1.0}, {'entity': 'ringed', 'concept_id': 'C0325501', 'confidence': 0.77345871925354}, {'entity': 'siderophages', 'concept_id': 'C1136253', 'confidence': 0.7251443266868591}], [{'entity': 'Hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}], [{'entity': 'Pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_250",
"caption_rating": "7"
},
{
"": "1007982",
"caption": "Round organisms at the periphery of histiocytes are about one to two microns in diameter.",
"image_path": "hoV-JkD6Wb0_image_ea64ba0e-0739-4808-8bc0-2186caddb7f0.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['round organisms', 'histiocytes', 'infected histiocytes', 'organisms of this size', 'cytoplasm', 'histoplasmosis', 'leishmaniasis', 'periphery of the cell', 'histiocytes', 'organisms of this size', 'cytoplasm', 'histoplasmosis', 'leishmaniasis']",
"noisy_text": " one to two microns. And we can use our erythrocyte here as kind of a ruler. Most erythrocytes and lymphocytes have nuclei that have diameters about five to six microns. And so you can see that these round organisms at the periphery of the histiocytes are about one to two microns. And as you'll see in a subsequent slide, when you see parasitized histiocytes with organisms of this size in the cytoplasm, you're either dealing with histoplasmosis or leishmaniasis. And of the two, leishmaniasis has a tendency to cluster at the periphery of the cell producing the so-called marquee sign",
"corrected_text": " one to two microns. And we can use our erythrocyte here as kind of a ruler. Most erythrocytes and lymphocytes have nuclei that have diameters about five to six microns. And so you can see that these round organisms at the periphery of the histiocytes are about one to two microns. And as you'll see in a subsequent slide, when you see infected histiocytes with organisms of this size in the cytoplasm, you're either dealing with histoplasmosis or leishmaniasis. And of the two, leishmaniasis has a tendency to cluster at the periphery of the cell producing the socalled marquee sign",
"med_umls_ids": "[[{'entity': 'Round organisms', 'concept_id': 'C0029235', 'confidence': 0.813967227935791}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'microns', 'concept_id': 'C0439201', 'confidence': 0.9999999403953552}, {'entity': 'diameter', 'concept_id': 'C1301886', 'confidence': 1.0}], [{'entity': 'Infected', 'concept_id': 'C0439663', 'confidence': 1.0}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'organisms', 'concept_id': 'C0029235', 'confidence': 0.9999998807907104}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'cytoplasm', 'concept_id': 'C0010834', 'confidence': 1.0}, {'entity': 'histoplasmosis', 'concept_id': 'C0019655', 'confidence': 1.0}, {'entity': 'leishmaniasis', 'concept_id': 'C0023281', 'confidence': 1.0}], [{'entity': 'Leishmaniasis', 'concept_id': 'C0023281', 'confidence': 1.0}, {'entity': 'cluster', 'concept_id': 'C1555715', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'cell', 'concept_id': 'C0007634', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_251",
"caption_rating": "7"
},
{
"": "1005120",
"caption": "Interconnected cords and strands with a cribriform pattern are observed.",
"image_path": "8S4LeiO6Bbk_image_16dcef57-bfaa-4dd7-9077-d079e0cacb50.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['neoplastic process', 'blue tumor', 'nuclei', 'epithelial tumor', 'cribriform pattern']",
"noisy_text": " again, a very, very nice biopsy. Moving on to slide number three, we're changing directions here. Here we have several fragments of tissue and in looking at this, this is pretty clear that we're dealing with a neoplastic process. It's somewhat fragmented, but seems to be fairly well circumscribed. At scan, one can see that we've got a blue tumor or blue ball present here, and the blue staining is generally due to hematoxylin staining the nucleus. So we've got a lot of nuclei here that we'll want to take a look at. Overall, even though this is fragmented, the fact that it's fairly well circumscribed would indicate that it's got more of a benign silhouette. If we move to higher power, we can see that we're dealing with an epithelial rather than a mosaicable tumor. We've got interconnected cords and strands. We have somewhat of a ribiform pattern here, and",
"corrected_text": " again, a very, very nice biopsy. Moving on to slide number three, we're changing directions here. Here we have several fragments of tissue and in looking at this, this is pretty clear that we're dealing with a neoplastic process. It's somewhat fragmented, but seems to be fairly well circumscribed. At scan, one can see that we've got a blue tumor or blue ball present here, and the blue staining is generally due to hematoxylin staining the nucleus. So we've got a lot of nuclei here that we'll want to take a look at. Overall, even though this is fragmented, the fact that it's fairly well circumscribed would indicate that it's got more of a benign silhouette. If we move to higher power, we can see that we're dealing with an epithelial rather than a mesenchymal tumor. We've got interconnected cords and strands. We have somewhat of a cribriform pattern here, and",
"med_umls_ids": "[[{'entity': 'Neoplastic process', 'concept_id': 'C0027671', 'confidence': 1.0}, {'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'fragments', 'concept_id': 'C0332255', 'confidence': 1.0}], [{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'well-circumscribed', 'concept_id': 'C1707398', 'confidence': 0.9430561065673828}, {'entity': 'blue staining', 'concept_id': 'C0025746', 'confidence': 0.7925992608070374}, {'entity': 'hematoxylin staining', 'concept_id': 'C0018964', 'confidence': 0.9091285467147827}, {'entity': 'nucleus', 'concept_id': 'C0007610', 'confidence': 1.0}], [{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'epithelial', 'concept_id': 'C0221908', 'confidence': 1.0}, {'entity': 'mesenchymal origin', 'concept_id': 'C1513143', 'confidence': 0.8364232778549194}], [{'entity': 'Interconnected', 'concept_id': 'C0683595', 'confidence': 0.8500909209251404}, {'entity': 'cords', 'concept_id': 'C0034869', 'confidence': 0.801885187625885}, {'entity': 'strands', 'concept_id': 'C0600383', 'confidence': 0.800572395324707}, {'entity': 'cribriform pattern', 'concept_id': 'C1333163', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_252",
"caption_rating": "9"
},
{
"": "1006119",
"caption": "Atypical fibroxanthoma is a malignant tumor that does not arise from muscle cells.",
"image_path": "LlPaENuqzVQ_image_8aba35ce-9548-4687-84be-cb4024c91599.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['smooth muscle', 'skeletal muscle', 'spindle cell non-epithelial neoplasms', 'atypical fibroxanthoma', 'neural tumors']",
"noisy_text": " So basically, just to kind of go backwards, more generic, muscle. Yeah. Do it. OK. And then there's two types of muscle, right? There's smooth muscle, or three, cardiac muscle, hopefully, to see that in the skin. But smooth and skeletal muscle, which we hardly ever see skeletal muscle neoplasms in dermatology. So it's almost always smooth muscle when we're looking at muscle. And there's probably really only two or three spindle cell non-epithelial neoplasms you need to know about. So muscle's one. What are the other two, basically? Like AFX? Yeah, but more generic. So what's the differentiation in an atypical fibrous anthoma? Just think of the cells that have become malignant in that. They're obviously not muscle cells. Neural? Neural's the other one. Those are the three major ones. But the one that you're missing is the center one there. What else lives in your dermis normally here? So we're going to go back. Fibroblast. Yeah,",
"corrected_text": " So basically, just to kind of go backwards, more generic, muscle. Yeah. Do it. OK. And then there's two types of muscle, right? There's smooth muscle, or three, cardiac muscle, hopefully, to see that in the skin. But smooth and skeletal muscle, which we hardly ever see skeletal muscle neoplasms in dermatology. So it's almost always smooth muscle when we're looking at muscle. And there's probably really only two or three spindle cell non-epithelial neoplasms you need to know about. So muscle's one. What are the other two, basically? Like AFX? Yeah, but more generic. So what's the differentiation in an atypical fibroxanthoma? Just think of the cells that have become malignant in that. They're obviously not muscle cells. Neural? Neural's the other one. Those are the three major ones. But the one that you're missing is the center one there. What else lives in your dermis normally here? So we're going to go back. Fibroblast. Yeah,",
"med_umls_ids": "[[{'entity': 'Smooth', 'concept_id': 'C0205357', 'confidence': 1.0}, {'entity': 'skeletal muscle', 'concept_id': 'C0242692', 'confidence': 1.0}, {'entity': 'muscle', 'concept_id': 'C0026845', 'confidence': 1.0}, {'entity': 'smooth muscle', 'concept_id': 'C1267092', 'confidence': 1.0}, {'entity': 'dermatology', 'concept_id': 'C0011627', 'confidence': 1.0}], [{'entity': 'Spindle cell', 'concept_id': 'C0682540', 'confidence': 0.9999999403953552}, {'entity': 'non-epithelial neoplasms', 'concept_id': 'C1368683', 'confidence': 0.8066584467887878}, {'entity': 'muscle', 'concept_id': 'C0026845', 'confidence': 1.0}, {'entity': 'neural tumors', 'concept_id': 'C1334956', 'confidence': 0.849646270275116}], [{'entity': 'Atypical fibroxanthoma', 'concept_id': 'C0346053', 'confidence': 1.0}, {'entity': 'malignant tumor', 'concept_id': 'C0006826', 'confidence': 1.0}, {'entity': 'muscle cells', 'concept_id': 'C0596981', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_253",
"caption_rating": "7"
},
{
"": "1007162",
"caption": "Metastatic melanoma may not involve epidermis and is usually as deep as it is wide.",
"image_path": "LlPaENuqzVQ_image_e0744ed1-9acb-4606-9ddb-9b899986c724.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['Metastatic malignant melanoma', 'Neoplastic cells', 'Epidermal involvement', 'Regional histologic satellite Mets', 'Metastatic malignant melanoma', 'Neoplastic cells', 'Epidermal involvement', 'Regional histologic satellite Mets']",
"noisy_text": " And this is an example of metastatic malignant melanoma. So, again, if you see neoplastic cells, there's several different ways you get metastases to the skin. One is like multiple little nodular aggregations, large nodular aggregations. You can get the cords and strands between them and collagen. So occasionally you get like intravascular, both if you're lymphatic or also intro, you know, blood vessel neoplastic cells, those might have been in lymphatics, but, you know, sometimes are actually within blood vessels themselves. One other clue that you're dealing with a metastatic melanoma rather than a primary melanoma, if there's really not any epidermal involvement, often it's just as deep as it is wide. And if you ever see patients that have metastatic, you know, like regional histologic satellite Mets, they're usually little small bumps. They're not usually large plaques or subcutaneous nodules and those kind of things if they're the kind of regional Mets. And those are almost as usually they're kind of as deep as they are broad. So you don't want to like treat those like their second primary melanomas and measure them and count mitoses and all that kind of stuff because it's a different animal. They've got a metastatic process and excising metastases generally doesn't improve the patient's prognosis. So this is an example of a metastatic melanoma versus that metastatic extravascular breast cancer, which is kind of an unusual pattern. Could you",
"corrected_text": " And this is an example of metastatic malignant melanoma. So, again, if you see neoplastic cells, there's several different ways you get metastases to the skin. One is like multiple little nodular aggregations, large nodular aggregations. You can get the cords and strands between them and collagen. So occasionally you get like intravascular, both if you're lymphatic or also intro, you know, blood vessel neoplastic cells, those might have been in lymphatics, but, you know, sometimes are actually within blood vessels themselves. One other clue that you're dealing with a metastatic melanoma rather than a primary melanoma, if there's really not any epidermal involvement, often it's just as deep as it is wide. And if you ever see patients that have metastatic, you know, like regional histologic satellite Mets, they're usually little small bumps. They're not usually large plaques or subcutaneous nodules and those kind of things if they're the kind of regional Mets. And those are almost as usually they're kind of as deep as they are broad. So you don't want to like treat those like their second primary melanomas and measure them and count mitoses and all that kind of stuff because it's a different animal. They've got a metastatic process and excising metastases generally doesn't improve the patient's prognosis. So this is an example of a metastatic melanoma versus that metastatic extravascular breast cancer, which is kind of an unusual pattern. Could you",
"med_umls_ids": "[[{'entity': 'metastatic malignant melanoma', 'concept_id': 'C0860594', 'confidence': 1.0}, {'entity': 'neoplastic cells', 'concept_id': 'C0597032', 'confidence': 1.0}, {'entity': 'metastases', 'concept_id': 'C0027627', 'confidence': 1.0}, {'entity': 'skin', 'concept_id': 'C0444099', 'confidence': 1.0}], [{'entity': 'Metastatic melanoma', 'concept_id': 'C0278883', 'confidence': 1.0}, {'entity': 'epidermis', 'concept_id': 'C0014520', 'confidence': 1.0}, {'entity': 'deep', 'concept_id': 'C0205125', 'confidence': 0.9999999403953552}], [{'entity': 'Excising metastases', 'concept_id': 'C0027627', 'confidence': 0.7655529975891113}, {'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'prognosis', 'concept_id': 'C0033325', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_254",
"caption_rating": "7"
},
{
"": "1006404",
"caption": "Chronic atrophic gastritis with intestinal metaplasia and muscularization of the lamina propria is the diagnosis.",
"image_path": "r7OA0Trj5hQ_image_dea08b06-85dd-4419-b590-b677fadd042a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['muscle fibers', 'intestinal metaplasia', 'lamina propria']",
"noisy_text": " where, again, you can see the muscle fibers running into the lamina propria. If you are in doubt, you can use the trichrome strain, where you can identify the muscle running up there. And you can see nice intestinal metaplasia there. Again, the number of glands are less in here. So this is chronic atrophic gastritis with intestinal metaplasia with muscularization of the lamina propria. More than one pathology involved in this biopsy. Plastic changes seen above are known as TIS. Once they cross the muscular ischemicosa, then only they are eligible for T1. So muscular ischemicosa acts like",
"corrected_text": " where, again, you can see the muscle fibers running into the lamina propria. If you are in doubt, you can use the trichrome strain, where you can identify the muscle running up there. And you can see nice intestinal metaplasia there. Again, the number of glands are less in here. So this is chronic atrophic gastritis with intestinal metaplasia with muscularization of the lamina propria. More than one pathology involved in this biopsy. Plastic changes seen above are known as TIS. Once they cross the muscularis propria, then only they are eligible for T1. So muscularis propria acts like",
"med_umls_ids": "[[{'entity': 'Muscle fibers', 'concept_id': 'C0242697', 'confidence': 1.0}, {'entity': 'running', 'concept_id': 'C0035953', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}], [{'entity': 'Intestinal metaplasia', 'concept_id': 'C0334037', 'confidence': 1.0}], [{'entity': 'Chronic atrophic gastritis', 'concept_id': 'C0017154', 'confidence': 1.0}, {'entity': 'intestinal metaplasia', 'concept_id': 'C0334037', 'confidence': 1.0}, {'entity': 'muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'Plastic changes', 'concept_id': 'C0392747', 'confidence': 0.7598782777786255}, {'entity': 'TIS', 'concept_id': 'C0475413', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_255",
"caption_rating": "9"
},
{
"": "1007108",
"caption": "Coalescing masses of granuloma expanding the lamina propria may indicate an infectious process or sarcoidosis rather than Crohn\u2019s disease.",
"image_path": "sDFjOtMAYrk_image_bd78a499-7df9-4eaa-9442-5bfa70ba065e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['granuloma', 'granuloma', 'lamina propria', 'Crohn\u2019s disease', 'infectious process', 'sarcoidosis', 'uveitis']",
"noisy_text": " I like this place. So if you have big coalescing masses of granuloma, expanding your lamina propria, think something other than Crohn's. Think of infectious process, especially if they're necrotizing, but even if they're not, and also think of sarcoid. This patient had sarcoid. So I said, this is probably not IBD, clinicians came down, we want to look at the biopsy, of course. It turns out that they went back and talked to the patient. The patient has a history of uveitis with characteristic features that were good for sarcoidosis. Nobody knew about they treated the patient for sarcoid, re-biopsied the patient. And he was fine. There were no more granulomas on multiple repeat biopsies. And now compare those grannies with the grannies in Crohn's. So here's",
"corrected_text": " I like this place. So if you have big coalescing masses of granuloma, expanding your lamina propria, think something other than Crohn's. Think of infectious process, especially if they're necrotizing, but even if they're not, and also think of sarcoid. This patient had sarcoid. So I said, this is probably not IBD, clinicians came down, we want to look at the biopsy, of course. It turns out that they went back and talked to the patient. The patient has a history of uveitis with characteristic features that were good for sarcoidosis. Nobody knew about they treated the patient for sarcoid, re-biopsied the patient. And he was fine. There were no more granulomas on multiple repeat biopsies. And now compare those grannies with the grannies in Crohn's. So here's",
"med_umls_ids": "[[{'entity': 'Coalescing masses', 'concept_id': 'C4727092', 'confidence': 0.5960795283317566}, {'entity': 'granuloma', 'concept_id': 'C0018188', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'infectious process', 'concept_id': 'C0745283', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'Crohn\u2019s disease', 'concept_id': 'C0010346', 'confidence': 0.8916962146759033}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'history', 'concept_id': 'C0019664', 'confidence': 1.0}, {'entity': 'uveitis', 'concept_id': 'C0042164', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}], [{'entity': 'Re-biopsy', 'concept_id': 'C0005558', 'confidence': 0.6681398749351501}, {'entity': 'granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}, {'entity': 'treatment', 'concept_id': 'C0039798', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_256",
"caption_rating": "9"
},
{
"": "1006648",
"caption": "The only positive stain is the nuclear stain P63.",
"image_path": "iklRyY1nBIE_image_fbc5b269-fc07-4337-8b78-bc8312f6d9b0.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['nuclear stain', 'membranous cytoplasmic stain', 'prostate cancer', 'P63', 'nuclear stain', 'membranous cytoplasmic stain', 'prostate cancer', 'P63']",
"noisy_text": " if you look carefully, is actually negative. The only thing that is positive is a nuclear stain, which is the P63. Again, you want to look at your internal control. These are the glands that were comfortable or benign. You can see they're staining for both nuclear stain and membranous wispy cytoplasmic stain, which is the hemoglobin cytokeratin. In this baccalaureate case, the racemase was predominantly negative. There's a hint of staining in areas, but it's predominantly negative. What is striking, what is very striking, is the fact that the P63 is diffusely positive, which they found very odd. And so this",
"corrected_text": " if you look carefully, is actually negative. The only thing that is positive is a nuclear stain, which is the P63. Again, you want to look at your internal control. These are the glands that were comfortable or benign. You can see they're staining for both nuclear stain and membranous wispy cytoplasmic stain, which is the hemoglobin cytokeratin. In this baccalaureate case, the racemase was predominantly negative. There's a hint of staining in areas, but it's predominantly negative. What is striking, what is very striking, is the fact that the P63 is diffusely positive, which they found very odd. And so this",
"med_umls_ids": "[[{'entity': 'positive stain', 'concept_id': 'C1446409', 'confidence': 0.8016907572746277}, {'entity': 'nuclear stain', 'concept_id': 'C0521447', 'confidence': 0.8163275122642517}, {'entity': 'P63', 'concept_id': 'C1422009', 'confidence': 1.0}], [{'entity': 'internal control glands', 'concept_id': 'C0597937', 'confidence': 0.7678565979003906}, {'entity': 'staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'nuclear', 'concept_id': 'C0521447', 'confidence': 1.0}, {'entity': 'membranous', 'concept_id': 'C0025255', 'confidence': 1.0}], [{'entity': 'Racemase', 'concept_id': 'C0034503', 'confidence': 1.0}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'prostate cancer', 'concept_id': 'C0376358', 'confidence': 1.0}], [{'entity': 'P63', 'concept_id': 'C1422009', 'confidence': 1.0}, {'entity': 'diffusely', 'concept_id': 'C0205219', 'confidence': 0.8011853098869324}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_257",
"caption_rating": "8"
},
{
"": "1006369",
"caption": "The lesion tends to occur along the ulnar aspect of the fifth digit and can be bilateral.",
"image_path": "8S4LeiO6Bbk_image_0b555a52-b342-471e-b863-fcfab968abaa.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['nerve fascicles', 'spindle-shaped cells', 'rudimentary supernumerary digit', 'ulnar aspect of the fifth digit', 'acquired digital fibroma', 'acquired digital fibrokeratoma', 'trichilemmal cyst']",
"noisy_text": " core here we've got several well-defined nerve fascicles and the spindled cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions of course tend to occur along the ulnar eye aspect of the fifth digit. They're not infrequently bilateral and the key differential here of course is an acquired digital fibroma or an acquired digital fibrocarotoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if",
"corrected_text": " core here we've got several well-defined nerve fascicles and the spindle cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions of course tend to occur along the ulnar eye aspect of the fifth digit. They're not infrequently bilateral and the key differential here of course is an acquired digital fibroma or an acquired digital fibrokeratoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if",
"med_umls_ids": "[[{'entity': 'Well-defined nerve fascicles', 'concept_id': 'C1185741', 'confidence': 0.5682494640350342}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'S100', 'concept_id': 'C3273837', 'confidence': 1.0}, {'entity': 'SOX10', 'concept_id': 'C1420317', 'confidence': 0.9999998807907104}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'rudimentary supernumerary digit', 'concept_id': 'C0152427', 'confidence': 0.8142021894454956}], [{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'ulnar', 'concept_id': 'C0442044', 'confidence': 1.0}, {'entity': 'aspect', 'concept_id': 'C1547011', 'confidence': 1.0}, {'entity': 'fifth digit', 'concept_id': 'C0230403', 'confidence': 0.912693440914154}, {'entity': 'bilateral', 'concept_id': 'C0238767', 'confidence': 1.0}], [{'entity': 'differential diagnosis', 'concept_id': 'C0011906', 'confidence': 1.0}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}, {'entity': 'digital fibroma', 'concept_id': 'C4538745', 'confidence': 0.8997364640235901}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}], [{'entity': 'Trichilemmal cyst', 'concept_id': 'C2266788', 'confidence': 1.0}, {'entity': 'biopsy specimen', 'concept_id': 'C0677862', 'confidence': 1.0}, {'entity': 'slide number', 'concept_id': 'C3828004', 'confidence': 0.8261933326721191}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_258",
"caption_rating": "8"
},
{
"": "1005773",
"caption": "The finding of pyloric gland metaplasia can be difficult to spot in cases of inflammatory bowel disease.",
"image_path": "sDFjOtMAYrk_image_faaab02b-3102-4bb5-97d5-34e3a51d298c.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['pyloric gland metaplasia', 'inflammatory bowel disease']",
"noisy_text": " other like, collagenous colitis, other types of inflammatory processes? Yes. So, the other finding would be pyloric gland metaplasia, which I find a little bit more difficult to spot if you're not really looking for it because the glands kind of blend in to the, you know, the background colonic mucosa. But once you learn to look for it, you'll find and we'll see a little bit of it further down the road. So, this is a case of inflammatory bowel disease. And this is what I like to compare everything to in order to avoid labeling patients with IBD who don't have IBD and who should be receiving other treatments other than immune suppression. So, just have this, you know,",
"corrected_text": " other like, collagenous colitis, other types of inflammatory processes? Yes. So, the other finding would be pyloric gland metaplasia, which I find a little bit more difficult to spot if you're not really looking for it because the glands kind of blend in to the, you know, the background colonic mucosa. But once you learn to look for it, you'll find and we'll see a little bit of it further down the road. So, this is a case of inflammatory bowel disease. And this is what I like to compare everything to in order to avoid labeling patients with IBD who don't have IBD and who should be receiving other treatments other than immune suppression. So, just have this, you know,",
"med_umls_ids": "[[{'entity': 'finding', 'concept_id': 'C0037088', 'confidence': 1.0}, {'entity': 'pyloric gland metaplasia', 'concept_id': 'C4288813', 'confidence': 1.0}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'inflammatory bowel disease', 'concept_id': 'C0021390', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_259",
"caption_rating": "7"
},
{
"": "1009075",
"caption": "Prominent nucleoli are seen in the cells, but the NC ratio is overall low.",
"image_path": "sDFjOtMAYrk_image_7d5336a2-b407-43a5-865b-ee33a577ea03.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['prominent nucleoli', 'reactive cytologic atypia', 'chemotherapy or radiation', 'cancer', 'inflammatory bowel disease']",
"noisy_text": " I'm missing it. Okay. I think what's catching my eye for the most part is the prominent nucleolide, but what would you say about the NC ratio? Yeah, I think overall it's low. You have lots, loads of cytoplasm. Even though the nuclei are big, you have loads of cytoplasm. So, with this morphology, first of all, the question was, you know, inflammatory bowel disease. Okay, maybe, but the cytology is not great for the degree of reactive epithelial changes. Although you can have some crazy looking inflammatory bowel disease cases, it's really crazy. When I see crazy bizarre epithelial atypia, I think about treatment effect, either chemotherapy or radiation. Both of them can give you this crazy cytologic atypia that sometimes may actually make you think of cancer. We've got a couple of cases received in consultation. I'm remembering one specifically in the stomach where the question is, what about this cancer? And it wasn't. It was just crazy reactive epithelial changes in a patient who we didn't know, but the patient had received radiotherapy for lung cancer. And it definitely looked a lot like malignancy, but there was something not right about it. So, this patient was receiving at the same time chemotherapy for his pancreatic cancer. One thing you can see in patients, especially when they're receiving radiation,",
"corrected_text": " I'm missing it. Okay. I think what's catching my eye for the most part is the prominent nucleoli, but what would you say about the NC ratio? Yeah, I think overall it's low. You have lots, loads of cytoplasm. Even though the nuclei are big, you have loads of cytoplasm. So, with this morphology, first of all, the question was, you know, inflammatory bowel disease. Okay, maybe, but the cytology is not great for the degree of reactive epithelial changes. Although you can have some crazy looking inflammatory bowel disease cases, it's really crazy. When I see crazy bizarre epithelial atypia, I think about treatment effect, either chemotherapy or radiation. Both of them can give you this reactive cytologic atypia that sometimes may actually make you think of cancer. We've got a couple of cases received in consultation. I'm remembering one specifically in the stomach where the question is, what about this cancer? And it wasn't. It was just crazy reactive epithelial changes in a patient who we didn't know, but the patient had received radiotherapy for lung cancer. And it definitely looked a lot like malignancy, but there was something not right about it. So, this patient was receiving at the same time chemotherapy for his pancreatic cancer. One thing you can see in patients, especially when they're receiving radiation,",
"med_umls_ids": "[[{'entity': 'Prominent', 'concept_id': 'C0205402', 'confidence': 0.9999999403953552}, {'entity': 'nucleoli', 'concept_id': 'C0007609', 'confidence': 0.8710004091262817}, {'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'NC', 'concept_id': 'C0027964', 'confidence': 1.0}, {'entity': 'ratio', 'concept_id': 'C0456603', 'confidence': 1.0}, {'entity': 'low', 'concept_id': 'C0205251', 'confidence': 0.9999999403953552}], [{'entity': 'Reactive cytologic atypia', 'concept_id': 'C0333865', 'confidence': 0.8587049245834351}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'treatment effect', 'concept_id': 'C1518681', 'confidence': 1.0}, {'entity': 'chemotherapy', 'concept_id': 'C0013216', 'confidence': 1.0}, {'entity': 'radiation', 'concept_id': 'C0034519', 'confidence': 1.0}], [{'entity': 'Crazy', 'concept_id': 'C0424157', 'confidence': 0.6988691687583923}, {'entity': 'cancer', 'concept_id': 'C0006826', 'confidence': 0.9999998807907104}], [{'entity': 'Inflammatory bowel disease', 'concept_id': 'C0021390', 'confidence': 1.0}, {'entity': 'cytology', 'concept_id': 'C0010818', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_260",
"caption_rating": "8"
},
{
"": "1007416",
"caption": "The presence of adenocarcinoma of the prostate, with some conventional and necrotic patterns.",
"image_path": "iklRyY1nBIE_image_9901ed20-bb96-4693-9cc1-725d57dbf57d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['Adenocarcinoma of the prostate', 'Necrosis', 'Positive digital rectal examination', 'Elevated PSA levels']",
"noisy_text": " mixed with conventional prostate cancer, which you have. A little bit of this is conventional here. And then you can have other variants or other patterns. You can see this is more conventional here. And you even have necrosis there. So this is basically bad news for this patient. All right, so we're going to move to case five. Case five is a 56-year-old man who presented with a positive digital record examination and elevated PSA levels. So as you can see, the histories are now beginning to overlap. They are beginning to sound very similar to one another, even though we are seeing different things histologically. So this",
"corrected_text": " mixed with conventional prostate cancer, which you have. A little bit of this is conventional here. And then you can have other variants or other patterns. You can see this is more conventional here. And you even have necrosis there. So this is basically bad news for this patient. All right, so we're going to move to case five. Case five is a 56-year-old man who presented with a positive digital record examination and elevated PSA levels. So as you can see, the histories are now beginning to overlap. They are beginning to sound very similar to one another, even though we are seeing different things histologically. So this",
"med_umls_ids": "[[{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'adenocarcinoma', 'concept_id': 'C0001418', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'conventional', 'concept_id': 'C0439858', 'confidence': 1.0}, {'entity': 'necrotic', 'concept_id': 'C0027540', 'confidence': 1.0}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'digital rectal examination', 'concept_id': 'C0199900', 'confidence': 1.0}, {'entity': 'elevated', 'concept_id': 'C0205250', 'confidence': 0.9999999403953552}, {'entity': 'PSA', 'concept_id': 'C0138741', 'confidence': 1.0}, {'entity': 'levels', 'concept_id': 'C0441889', 'confidence': 1.0}, {'entity': 'prostate cancer', 'concept_id': 'C0376358', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_261",
"caption_rating": "7"
},
{
"": "1007194",
"caption": "Poorly differentiated cancer cells are visible in the submucosa.",
"image_path": "r7OA0Trj5hQ_image_f9ff777a-e3c6-475c-8473-886905465b82.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['submucosa', 'poorly differentiated cancer cells', 'invasive carcinoma', 'blood vessels', 'submucosa', 'poorly differentiated cancer cells', 'invasive carcinoma', 'blood vessels']",
"noisy_text": " And why I am showing it, sometimes you may think of malignancy. Here, you may not think of it. And another point, these are all the cells we are looking in congenital mecagola. So if you don't see them in the submicosa in frozen section, again, this will qualify for congenital mecagola. Here, another tricky thing. This is submicosa, and you can see the poorly differentiated cancer cells. And these are invasive carcinoma. Now, you see this number of blood vessels there. That's why we need the cancer cell to come into the submicosa to call it as cancer cell, because the incidence of metastasis is very",
"corrected_text": " And why I am showing it, sometimes you may think of malignancy. Here, you may not think of it. And another point, these are all the cells we are looking in congenital megacolon. So if you don't see them in the submucosa in frozen section, again, this will qualify for congenital megacolon. Here, another tricky thing. This is submucosa, and you can see the poorly differentiated cancer cells. And these are invasive carcinoma. Now, you see this number of blood vessels there. That's why we need the cancer cell to come into the submucosa to call it as cancer cell, because the incidence of metastasis is very",
"med_umls_ids": "[[{'entity': 'narrator', 'concept_id': 'C1135957', 'confidence': 0.7711340188980103}, {'entity': 'malignancy', 'concept_id': 'C0006826', 'confidence': 1.0}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'congenital megacolon', 'concept_id': 'C0019569', 'confidence': 1.0}], [{'entity': 'Poorly differentiated', 'concept_id': 'C0205617', 'confidence': 1.0}, {'entity': 'cancer cells', 'concept_id': 'C0334227', 'confidence': 0.9999998807907104}, {'entity': 'visible', 'concept_id': 'C0205379', 'confidence': 0.9999998807907104}, {'entity': 'submucosa', 'concept_id': 'C0225344', 'confidence': 1.0}], [{'entity': 'cancer cells', 'concept_id': 'C0334227', 'confidence': 0.9999998807907104}, {'entity': 'invade', 'concept_id': 'C1517574', 'confidence': 0.857607364654541}, {'entity': 'submucosa', 'concept_id': 'C0225344', 'confidence': 1.0}, {'entity': 'cancerous', 'concept_id': 'C1514391', 'confidence': 0.763753354549408}, {'entity': 'incidence', 'concept_id': 'C0021149', 'confidence': 1.0}, {'entity': 'metastasis', 'concept_id': 'C0027627', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_262",
"caption_rating": "8"
},
{
"": "1008912",
"caption": "Honeycomb morphology is a clue to the diagnosis of desmoplastic fibroblastoma (DFSP).",
"image_path": "LlPaENuqzVQ_image_8d7a5078-12be-49d3-8929-42114f40a33a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['honeycomb morphology', 'lipocytes', 'typical storiform pattern']",
"noisy_text": " this is a clue to this diagnosis. You can make this diagnosis at low power when you see this pattern. This is a honeycomb morphology. Rarely anything does this except dramatic fibrosarcoma tuberans. Okay, when you see this pattern, you can impress your friends and colleagues. You can say, this is DFSB. You don't need the storiform pattern. If you see this, you got the diagnosis. No other neoplasm really gets diffusely between and among lipocytes in a diffuse pattern like this, other than DFSB. Now you look up here and yeah, you do have the nice, beautiful storiform pattern here. And you don't really need a CD34 stain here. You can do it",
"corrected_text": " this is a clue to this diagnosis. You can make this diagnosis at low power when you see this pattern. This is a honeycomb morphology. Rarely anything does this except desmoplastic fibroblastoma. Okay, when you see this pattern, you can impress your friends and colleagues. You can say, this is DFSP. You don't need the typical storiform pattern. If you see this, you got the diagnosis. No other neoplasm really gets diffusely between and among lipocytes in a diffuse pattern like this, other than DFSP. Now you look up here and yeah, you do have the nice, typical typical storiform pattern here. And you don't really need a CD34 stain here. You can do it",
"med_umls_ids": "[[{'entity': 'Honeycomb', 'concept_id': 'C0332468', 'confidence': 1.0}, {'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'desmoplastic fibroblastoma', 'concept_id': 'C0206645', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}], [{'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}, {'entity': 'neoplasm', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'diffusely', 'concept_id': 'C0205219', 'confidence': 0.8011853098869324}, {'entity': 'lipocytes', 'concept_id': 'C0206131', 'confidence': 1.0}, {'entity': 'diffuse pattern', 'concept_id': 'C1333299', 'confidence': 0.9999998807907104}], [{'entity': 'storiform pattern', 'concept_id': 'C1336510', 'confidence': 0.8142904043197632}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_263",
"caption_rating": "7"
},
{
"": "1009475",
"caption": "Low-grade fibromyxoid sarcomas with swirling growth can mimic perineuriomas and often express Clodin-1.",
"image_path": "QDb68_G1HR4_image_1e4ca39c-40f6-492b-b7c7-c8e20bfaf5f5.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Deep soft tissue', 'Perineurioma', 'Low-grade fibromyxoid sarcoma', 'Immunohistochemistry', 'Swirling growth']",
"noisy_text": " involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is more of a difficult problem because perineurioma has a lot of overlap histologically with low-grade fibromyxoid sarcoma and also immunohistochemically. On immunostains, EMA, Clodin-1 and Glut-1 are three immunostains that will usually stain perineuriomas. The problem is that low-grade fibromyxoid sarcomas often express at least focal EMA, so that's a problem and additionally, the examples of low-grade fibromyxoid sarcoma that have dramatic swirling and whirling growth, those are the ones that have a perineurioma like pattern, the ones that mimic perineurioma. They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The",
"corrected_text": " involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is more of a difficult problem because perineurioma has a lot of overlap histologically with low-grade fibromyxoid sarcoma and also immunohistochemically. On immunostains, EMA, Clodin-1 and Glut-1 are three immunostains that will usually stain perineuriomas. The problem is that low-grade fibromyxoid sarcomas often express at least focal EMA, so that's a problem and additionally, the examples of low-grade fibromyxoid sarcoma that have dramatic swirling and whirling growth, those are the ones that have a perineurioma like pattern, the ones that mimic perineurioma. They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The",
"med_umls_ids": "[[{'entity': 'CD34', 'concept_id': 'C0054953', 'confidence': 1.0}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'deep soft tissue tumors', 'concept_id': 'C0037579', 'confidence': 0.8622524738311768}], [{'entity': 'Perineurioma', 'concept_id': 'C0751691', 'confidence': 0.9999999403953552}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'histologically', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'immunohistochemistry', 'concept_id': 'C0021044', 'confidence': 0.9999998807907104}], [{'entity': 'EMA', 'concept_id': 'C0268596', 'confidence': 0.9999999403953552}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}, {'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'immunohistochemical stains', 'concept_id': 'C4317108', 'confidence': 0.9999999403953552}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibrosarcomas', 'concept_id': 'C0016057', 'confidence': 1.0}, {'entity': 'EMA', 'concept_id': 'C0268596', 'confidence': 0.9999999403953552}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}], [{'entity': 'Low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'swirling', 'concept_id': 'C0233591', 'confidence': 0.7064549922943115}, {'entity': 'growth', 'concept_id': 'C0018270', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'express', 'concept_id': 'C0017262', 'confidence': 0.8176293969154358}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}], [{'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'reports', 'concept_id': 'C0684224', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcomas', 'concept_id': 'C1275282', 'confidence': 0.8123146891593933}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_264",
"caption_rating": "8"
},
{
"": "1006805",
"caption": "Intraductal carcinoma of the prostate is usually due to invasion, colonization by adjacent invasive tumor.",
"image_path": "iklRyY1nBIE_image_06474144-5c48-46a7-8e65-c93b6249c886.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['basal cells at the periphery', 'enlarged nuclei', 'intraductal carcinoma of the prostate', 'adjacent invasive tumor', 'previously benign gland', 'basal cells at the periphery', 'enlarged nuclei', 'intraductal carcinoma of the prostate', 'adjacent invasive tumor', 'previously benign gland']",
"noisy_text": " Let me show you what the cocktail looks like. Again, this is the pin three, or some call it pin four. You have the P63, you have the hemoglobin cytokeratin, and then you have the racemase, which is the pink chromogen. And as you can see, as I demonstrated on the H&E, basal cells are indeed present. This is too much for high-grade pin. This is basically what is called a solid cribriform kind of pattern, in which over 50% of the lumen is filled by tumor cells. So this is way too much for high-grade pin. But it's not invasive, because you have basal cells at the periphery. And the nuclei are enlarged. These nuclei are about six times the size of normal prostate nuclei. So this case meets the criteria for introductal carcinoma of the prostate. There is an invasive component, which you can see is negative for basal cell markers. But you have the introductal component. And this is a very interesting entity. The vast majority of cases, and I'll show you the corresponding radical prostatectomy specimens in a second, but the vast majority of these so-called introductal carcinoma of the prostate is due to invasion, colonization by adjacent invasive tumor. And it usually occurs in patients that have high-volume tumors. When I show you the corresponding radical prostatectomies, you'll see what I'm talking about. You usually don't have this in patients in their radicals that have 5% prostate cancer or 10% prostate cancer. It's usually patients that have extensive prostate cancer involvement, and the invasive glands basically have nowhere else to go but to colonize adjacent benign glands. And I'll demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues,",
"corrected_text": " Let me show you what the cocktail looks like. Again, this is the pin three, or some call it pin four. You have the P63, you have the hemoglobin cytokeratin, and then you have the racemase, which is the AMACR. And as you can see, as I demonstrated on the H&E, basal cells are indeed present. This is too much for high-grade pin. This is basically what is called a solid cribriform kind of pattern, in which over 50% of the lumen is filled by tumor cells. So this is way too much for high-grade pin. But it's not invasive, because you have basal cells at the periphery. And the nuclei are enlarged. These nuclei are about six times the size of normal prostate nuclei. So this case meets the criteria for intraductal carcinoma of the prostate. There is an invasive component, which you can see is negative for basal cell markers. But you have the intraductal component. And this is a very interesting entity. The vast majority of cases, and I'll show you the corresponding radical prostatectomy specimens in a second, but the vast majority of these so-called intraductal carcinoma of the prostate is due to invasion, colonization by adjacent invasive tumor. And it usually occurs in patients that have high-volume tumors. When I show you the corresponding radical prostatectomies, you'll see what I'm talking about. You usually don't have this in patients in their radicals that have 5% prostate cancer or 10% prostate cancer. It's usually patients that have extensive prostate cancer involvement, and the invasive glands basically have nowhere else to go but to colonize adjacent benign glands. And I'demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues,",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'cocktail', 'concept_id': 'C0678420', 'confidence': 1.0}, {'entity': 'markers', 'concept_id': 'C0181734', 'confidence': 0.890313982963562}, {'entity': 'intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate diagnosis', 'concept_id': 'C0011900', 'confidence': 0.7927443981170654}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'basal cells', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}], [{'entity': 'Enlarged nuclei', 'concept_id': 'C4013177', 'confidence': 0.7774685621261597}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'normal', 'concept_id': 'C0205307', 'confidence': 1.0}], [{'entity': 'Intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'invasion', 'concept_id': 'C1269955', 'confidence': 1.0}, {'entity': 'colonization', 'concept_id': 'C4289767', 'confidence': 1.0}, {'entity': 'adjacent', 'concept_id': 'C0205117', 'confidence': 1.0}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}], [{'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'benign gland', 'concept_id': 'C0205183', 'confidence': 0.7986565828323364}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_265",
"caption_rating": "8"
},
{
"": "1005916",
"caption": "The lesion tends to occur along the ulnar aspect of the fifth digit and can be bilateral.",
"image_path": "8S4LeiO6Bbk_image_ad937ed9-c964-4790-801d-07e966b97fd9.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['nerve fascicles', 'spindle-shaped cells', 'rudimentary supernumerary digit', 'ulnar aspect of the fifth digit', 'acquired digital fibroma', 'acquired digital fibrokeratoma', 'trichilemmal cyst']",
"noisy_text": " core here we've got several well-defined nerve fascicles and the spindled cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions of course tend to occur along the ulnar eye aspect of the fifth digit. They're not infrequently bilateral and the key differential here of course is an acquired digital fibroma or an acquired digital fibrocarotoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if",
"corrected_text": " core here we've got several well-defined nerve fascicles and the spindle cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions of course tend to occur along the ulnar eye aspect of the fifth digit. They're not infrequently bilateral and the key differential here of course is an acquired digital fibroma or an acquired digital fibrokeratoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if",
"med_umls_ids": "[[{'entity': 'Well-defined nerve fascicles', 'concept_id': 'C1185741', 'confidence': 0.5682494640350342}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'S100', 'concept_id': 'C3273837', 'confidence': 1.0}, {'entity': 'SOX10', 'concept_id': 'C1420317', 'confidence': 0.9999998807907104}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'rudimentary supernumerary digit', 'concept_id': 'C0152427', 'confidence': 0.8142021894454956}], [{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'ulnar', 'concept_id': 'C0442044', 'confidence': 1.0}, {'entity': 'aspect', 'concept_id': 'C1547011', 'confidence': 1.0}, {'entity': 'fifth digit', 'concept_id': 'C0230403', 'confidence': 0.912693440914154}, {'entity': 'bilateral', 'concept_id': 'C0238767', 'confidence': 1.0}], [{'entity': 'differential diagnosis', 'concept_id': 'C0011906', 'confidence': 1.0}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}, {'entity': 'digital fibroma', 'concept_id': 'C4538745', 'confidence': 0.8997364640235901}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}], [{'entity': 'Trichilemmal cyst', 'concept_id': 'C2266788', 'confidence': 1.0}, {'entity': 'biopsy specimen', 'concept_id': 'C0677862', 'confidence': 1.0}, {'entity': 'slide number', 'concept_id': 'C3828004', 'confidence': 0.8261933326721191}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_266",
"caption_rating": "8"
},
{
"": "1006858",
"caption": "Presence of several melanocytes, some forming nests, some as confluence solitary units, along the base of the matrix epithelium in the matrix layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern.",
"image_path": "8S4LeiO6Bbk_image_759de876-54a9-488a-8cee-29032ba566e8.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Presence of several melanocytes', 'too many melanocytes', 'Presence of several melanocytes', 'too many melanocytes']",
"noisy_text": " examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matricle epithelium in the matricle layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that being said, we'll go ahead and move on to slide number two, which was a melanin A or Mk1 immunohistochemical stain of this same piece of tissue. Underneath this bubble here we have our control. This is",
"corrected_text": " examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matrix epithelium in the matrix layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that being said, we'll go ahead and move on to slide number two, which was a melanin A or Mk1 immunohistochemical stain of this same piece of tissue. Underneath this bubble here we have our control. This is",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'nests', 'concept_id': 'C0035253', 'confidence': 0.7275967001914978}, {'entity': 'confluence', 'concept_id': 'C0226863', 'confidence': 0.857487678527832}, {'entity': 'solitary units', 'concept_id': 'C0205171', 'confidence': 0.7227572798728943}, {'entity': 'base', 'concept_id': 'C0002055', 'confidence': 1.0}, {'entity': 'matrix epithelium', 'concept_id': 'C0014609', 'confidence': 0.7584323883056641}, {'entity': 'matrix layer', 'concept_id': 'C0331858', 'confidence': 0.71736741065979}, {'entity': 'basal layer', 'concept_id': 'C0221925', 'confidence': 1.0}, {'entity': 'matrix', 'concept_id': 'C0331858', 'confidence': 1.0}, {'entity': 'upper portions', 'concept_id': 'C0449719', 'confidence': 0.6251541972160339}, {'entity': 'matrix', 'concept_id': 'C0331858', 'confidence': 1.0}, {'entity': 'pagetoid', 'concept_id': 'C1518847', 'confidence': 0.8801172375679016}, {'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}], [{'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'matrix', 'concept_id': 'C0331858', 'confidence': 1.0}, {'entity': 'suspicious', 'concept_id': 'C0750493', 'confidence': 1.0}, {'entity': 'melanoma', 'concept_id': 'C0025202', 'confidence': 1.0}, {'entity': 'in situ', 'concept_id': 'C0444498', 'confidence': 0.9999999403953552}]]",
"magnification": "1.0",
"height": "758.0",
"width": "1920.0",
"id": "test_267",
"caption_rating": "9"
},
{
"": "1006839",
"caption": "Histopathological description of a specimen with banal appearing melanocytes present within the dermis.",
"image_path": "8S4LeiO6Bbk_image_ac0d9a67-6f97-4a09-b8a8-4b4299ed5ec3.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['cytoplasm']",
"noisy_text": " appearance, a round oval nuclei and a moderate amount of cytoplasm. And then we have nest cords and strands of otherwise banal appearing or banal appearing melanocytes present within the underlying dermis. There is evidence of maturation with depth in these sections, and no mitotic pairs. In the central portion of the specimen, you can see that the dermis is a little more sclerotic. And we've got the presence of separately heavily pigmented melanovagias. And then if we look at our top piece of tissue, again, we have the more banal appearing melanocytes out of the periphery. And centrally, we've got embedded within a sclerotic stroma a second distinct morphologic population of melanocytes. Some of these are dendritic, others have spindled or fusiform-shaped",
"corrected_text": " appearance, a round oval nuclei and a moderate amount of cytoplasm. And then we have nest cords and strands of otherwise banal appearing or banal appearing melanocytes present within the underlying dermis. There is evidence of maturation with depth in these sections, and no mitotic pairs. In the central portion of the specimen, you can see that the dermis is a little more sclerotic. And we've got the presence of separately heavily pigmented melanovagias. And then if we look at our top piece of tissue, again, we have the more banal appearing melanocytes out of the periphery. And centrally, we've got embedded within a sclerotic stroma a second distinct morphologic population of melanocytes. Some of these are dendritic, others have spindle-shaped or fusiform-shaped",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'specimen', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'banal', 'concept_id': 'C0004722', 'confidence': 0.7279530763626099}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}], [{'entity': 'Evidence', 'concept_id': 'C3887511', 'confidence': 1.0}, {'entity': 'maturation', 'concept_id': 'C0678723', 'confidence': 1.0}, {'entity': 'depth', 'concept_id': 'C0205125', 'confidence': 1.0}, {'entity': 'mitotic', 'concept_id': 'C1513354', 'confidence': 1.0}, {'entity': 'pairs', 'concept_id': 'C0600436', 'confidence': 0.8094210028648376}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'heavily', 'concept_id': 'C0337678', 'confidence': 0.6902515292167664}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'melanophages', 'concept_id': 'C3280463', 'confidence': 0.9375340938568115}], [{'entity': 'Sclerotic', 'concept_id': 'C0036429', 'confidence': 0.9999999403953552}, {'entity': 'stroma', 'concept_id': 'C0927195', 'confidence': 1.0}, {'entity': 'morphologic population', 'concept_id': 'C0543482', 'confidence': 0.699425995349884}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_268",
"caption_rating": "8"
},
{
"": "1005467",
"caption": "Enlarged nuclei that are about six times the size of normal prostate nuclei.",
"image_path": "iklRyY1nBIE_image_943dc3a5-3548-4b93-8b05-23755f6f6e2c.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['basal cells at the periphery', 'enlarged nuclei', 'intraductal carcinoma of the prostate', 'adjacent invasive tumor', 'previously benign gland', 'basal cells at the periphery', 'enlarged nuclei', 'intraductal carcinoma of the prostate', 'adjacent invasive tumor', 'previously benign gland']",
"noisy_text": " Let me show you what the cocktail looks like. Again, this is the pin three, or some call it pin four. You have the P63, you have the hemoglobin cytokeratin, and then you have the racemase, which is the pink chromogen. And as you can see, as I demonstrated on the H&E, basal cells are indeed present. This is too much for high-grade pin. This is basically what is called a solid cribriform kind of pattern, in which over 50% of the lumen is filled by tumor cells. So this is way too much for high-grade pin. But it's not invasive, because you have basal cells at the periphery. And the nuclei are enlarged. These nuclei are about six times the size of normal prostate nuclei. So this case meets the criteria for introductal carcinoma of the prostate. There is an invasive component, which you can see is negative for basal cell markers. But you have the introductal component. And this is a very interesting entity. The vast majority of cases, and I'll show you the corresponding radical prostatectomy specimens in a second, but the vast majority of these so-called introductal carcinoma of the prostate is due to invasion, colonization by adjacent invasive tumor. And it usually occurs in patients that have high-volume tumors. When I show you the corresponding radical prostatectomies, you'll see what I'm talking about. You usually don't have this in patients in their radicals that have 5% prostate cancer or 10% prostate cancer. It's usually patients that have extensive prostate cancer involvement, and the invasive glands basically have nowhere else to go but to colonize adjacent benign glands. And I'll demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues,",
"corrected_text": " Let me show you what the cocktail looks like. Again, this is the pin three, or some call it pin four. You have the P63, you have the hemoglobin cytokeratin, and then you have the racemase, which is the AMACR. And as you can see, as I demonstrated on the H&E, basal cells are indeed present. This is too much for high-grade pin. This is basically what is called a solid cribriform kind of pattern, in which over 50% of the lumen is filled by tumor cells. So this is way too much for high-grade pin. But it's not invasive, because you have basal cells at the periphery. And the nuclei are enlarged. These nuclei are about six times the size of normal prostate nuclei. So this case meets the criteria for intraductal carcinoma of the prostate. There is an invasive component, which you can see is negative for basal cell markers. But you have the intraductal component. And this is a very interesting entity. The vast majority of cases, and I'll show you the corresponding radical prostatectomy specimens in a second, but the vast majority of these so-called intraductal carcinoma of the prostate is due to invasion, colonization by adjacent invasive tumor. And it usually occurs in patients that have high-volume tumors. When I show you the corresponding radical prostatectomies, you'll see what I'm talking about. You usually don't have this in patients in their radicals that have 5% prostate cancer or 10% prostate cancer. It's usually patients that have extensive prostate cancer involvement, and the invasive glands basically have nowhere else to go but to colonize adjacent benign glands. And I'demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues,",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'cocktail', 'concept_id': 'C0678420', 'confidence': 1.0}, {'entity': 'markers', 'concept_id': 'C0181734', 'confidence': 0.890313982963562}, {'entity': 'intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate diagnosis', 'concept_id': 'C0011900', 'confidence': 0.7927443981170654}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'basal cells', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}], [{'entity': 'Enlarged nuclei', 'concept_id': 'C4013177', 'confidence': 0.7774685621261597}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'normal', 'concept_id': 'C0205307', 'confidence': 1.0}], [{'entity': 'Intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'invasion', 'concept_id': 'C1269955', 'confidence': 1.0}, {'entity': 'colonization', 'concept_id': 'C4289767', 'confidence': 1.0}, {'entity': 'adjacent', 'concept_id': 'C0205117', 'confidence': 1.0}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}], [{'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'benign gland', 'concept_id': 'C0205183', 'confidence': 0.7986565828323364}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_269",
"caption_rating": "8"
},
{
"": "1007015",
"caption": "Adenomatous changes with low-grade or high-grade dysplasia are seen in the GI tract, while dysplastic changes with low-grade and high-grade dysplasia are seen in other organs.",
"image_path": "r7OA0Trj5hQ_image_8066977d-350b-47ac-92f1-c9b71d448dfa.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " This concept of dysplasia, low-grade dysplasia and high-grade dysplasia is very, very essential because you can apply this criteria in any organ. You can apply it in the pancreas. You can apply it in the gallbladder. You can apply it in the bile duct. Even you can apply it in the breast. You can apply it in the prostate. You can apply it wherever you want. These are all in the GI tract known as adenomatous changes with the low-grade or high-grade dysplasia. In the other organs, it is known as dysplastic changes with the low-grade and the high-grade dysplasia. This is a beautiful picture I got it from the Google where it looks normal",
"corrected_text": " This concept of dysplasia, low-grade dysplasia and high-grade dysplasia is very, very essential because you can apply this criteria in any organ. You can apply it in the pancreas. You can apply it in the gallbladder. You can apply it in the bile duct. Even you can apply it in the breast. You can apply it in the prostate. You can apply it wherever you want. These are all in the GI tract known as adenomatous changes with the low-grade or high-grade dysplasia. In the other organs, it is known as dysplastic changes with the low-grade and the high-grade dysplasia. This is a beautiful picture I got it from the Google where it looks normal",
"med_umls_ids": "[[{'entity': 'concept', 'concept_id': 'C0178566', 'confidence': 1.0}, {'entity': 'dysplasia', 'concept_id': 'C0334044', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'dysplasia', 'concept_id': 'C0334044', 'confidence': 1.0}, {'entity': 'high-grade dysplasia', 'concept_id': 'C1333110', 'confidence': 0.8831341862678528}, {'entity': 'essential', 'concept_id': 'C0205224', 'confidence': 0.9999999403953552}, {'entity': 'organs', 'concept_id': 'C0178784', 'confidence': 1.0}, {'entity': 'pancreas', 'concept_id': 'C0030274', 'confidence': 0.9999999403953552}, {'entity': 'gallbladder', 'concept_id': 'C0016976', 'confidence': 0.9999999403953552}, {'entity': 'bile duct', 'concept_id': 'C0005400', 'confidence': 1.0}, {'entity': 'breast', 'concept_id': 'C0006141', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}], [{'entity': 'Adenomatous', 'concept_id': 'C0333981', 'confidence': 0.785536527633667}, {'entity': 'changes', 'concept_id': 'C0392747', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'high-grade dysplasia', 'concept_id': 'C1333110', 'confidence': 0.8831341862678528}, {'entity': 'GI tract', 'concept_id': 'C0017189', 'confidence': 1.0}, {'entity': 'dysplastic', 'concept_id': 'C0334044', 'confidence': 0.9999999403953552}, {'entity': 'changes', 'concept_id': 'C0392747', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'high-grade dysplasia', 'concept_id': 'C1333110', 'confidence': 0.8831341862678528}, {'entity': 'organs', 'concept_id': 'C0178784', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_270",
"caption_rating": "7"
},
{
"": "1008318",
"caption": "Granulomatous rosacea is the likely diagnosis.",
"image_path": "LlPaENuqzVQ_image_4619fb4f-a724-4098-99be-ac57f694e50b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['face', 'follicular pustule', 'histiocytes', 'lymphocytes', 'face', 'follicular pustule', 'histiocytes', 'lymphocytes']",
"noisy_text": " Oh, maybe there are some there on the other slide. But, oh, yeah, there's some. Not a lot, but, you know, there's mostly histiocytes predominated with lymphocytes. There's a couple of eos, but it's not... There aren't a lot. So that kind of made me think of granulomatous rosacea. Good. Excellent. That's exactly what it should make you think of. Very, very good. That's exactly what this is. So the face helps you, right? You're not going to see this on somebody's trunk. The follicular pustule helps too, right? Because rosacea can give you multiple different histologic reaction patterns. What are some of the forms of rosacea? So we've got two forms here. We've got papulopustular rosacea. We've got granulomatous rosacea. What are a couple other forms of rosacea? You could just have an ET type of just, you know, kind of like telangiectasia. Yes, good. The telangiectatic type of rosacea. What's one other one that we get sometimes? I guess there's other... I mean, I don't",
"corrected_text": " Oh, maybe there are some there on the other slide. But, oh, yeah, there's some. Not a lot, but, you know, there's mostly histiocytes predominated with lymphocytes. There's a couple of eos, but it's not... There aren't a lot. So that kind of made me think of granulomatous rosacea. Good. Excellent. That's exactly what it should make you think of. Very, very good. That's exactly what this is. So the face helps you, right? You're not going to see this on somebody's trunk. The follicular pustule helps too, right? Because rosacea can give you multiple different histologic reaction patterns. What are some of the forms of rosacea? So we've got two forms here. We've got papulopustular rosacea. We've got granulomatous rosacea. What are a couple other forms of rosacea? You could just have an ET type of just, you know, kind of like telangiectasia. Yes, good. The telangiectatic type of rosacea. What's one other one that we get sometimes? I guess there's other... I mean, I don't",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'skin condition', 'concept_id': 'C1719933', 'confidence': 1.0}, {'entity': 'predominance', 'concept_id': 'C1835590', 'confidence': 0.8840479850769043}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}], [{'entity': 'Granulomatous rosacea', 'concept_id': 'C1275718', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'Rosacea', 'concept_id': 'C0035854', 'confidence': 1.0}, {'entity': 'multiple', 'concept_id': 'C0439064', 'confidence': 1.0}, {'entity': 'histologic reaction', 'concept_id': 'C0205462', 'confidence': 0.8118124008178711}, {'entity': 'papulopustular rosacea', 'concept_id': 'C1449853', 'confidence': 1.0}, {'entity': 'telangiectatic type', 'concept_id': 'C4014149', 'confidence': 0.7599172592163086}, {'entity': 'rosacea', 'concept_id': 'C0035854', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_271",
"caption_rating": "8"
},
{
"": "1005445",
"caption": "Discussion of the unusual behavior of a tumor that looks benign but has a different behavior than other sarcomas, with a median time to metastasis of 15 years and cases reported up to 30 or 40 years after the original diagnosis.",
"image_path": "QDb68_G1HR4_image_23701937-42d3-4de6-886e-e93e779aa5e6.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['metastases to lung or pleura']",
"noisy_text": " If you follow patients much longer, the picture changes quite a bit and a significant subset, somewhere around 40 or even maybe even higher percent will eventually get metastases if you follow them over decades and that's what's so unusual about this tumor, not only does it look benign, it is a very, very different behavior than other sarcomas. Most high-grade sarcomas metastasize oftentimes within 5 years of diagnosis if they're going to metastasize. Now that's not always true, but oftentimes that's the case. This tumor is so different, I think the median time to metastasis in a large retrospective study by Harry Evans, I think that was published in American Journal of Surgical Pathology 2011, I'll put a link in the video description. If you follow them for many, many years, the average time, I think it was the median time actually to recurrence or to metastasis was 15 years, that's so strange, right, to have a tumor that waits 15 years to eventually spread or recur and that's not all. There are cases reported that are actually 30 or even 40 years out from the original diagnosis when a metastasis finally shows up. So unfortunately, that's a frustrating thing I think for both the treating physicians and the patients to know that basically you're never totally in the clear these things can recur or metastasize very, very long after diagnosis. When they metastasize, they often go to the lung or the pleura and there probably is some benefit at least",
"corrected_text": " If you follow patients much longer, the picture changes quite a bit and a significant subset, somewhere around 40 or even maybe even higher percent will eventually get metastases if you follow them over decades and that's what's so unusual about this tumor, not only does it look benign, it is a very, very different behavior than other sarcomas. Most high-grade sarcomas metastasize oftentimes within 5 years of diagnosis if they're going to metastasize. Now that's not always true, but oftentimes that's the case. This tumor is so different, I think the median time to metastasis in a large retrospective study by Harry Evans, I think that was published in American Journal of Surgical Pathology 2011, I'll put a link in the video description. If you follow them for many, many years, the average time, I think it was the median time actually to recurrence or to metastasis was 15 years, that's so strange, right, to have a tumor that waits 15 years to eventually spread or recur and that's not all. There are cases reported that are actually 30 or even 40 years out from the original diagnosis when a metastasis finally shows up. So unfortunately, that's a frustrating thing I think for both the treating physicians and the patients to know that basically you're never totally in the clear these things can recur or metastasize very, very long after diagnosis. When they metastasize, they often go to the lung or the pleura and there probably is some benefit at least",
"med_umls_ids": "[[{'entity': 'unusual', 'concept_id': 'C2700116', 'confidence': 1.0}, {'entity': 'behavior', 'concept_id': 'C0004927', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'benign', 'concept_id': 'C0205183', 'confidence': 1.0}, {'entity': 'behavior', 'concept_id': 'C0004927', 'confidence': 1.0}, {'entity': 'sarcomas', 'concept_id': 'C1261473', 'confidence': 1.0}, {'entity': 'median', 'concept_id': 'C0549183', 'confidence': 1.0}, {'entity': 'metastasis', 'concept_id': 'C0027627', 'confidence': 1.0}, {'entity': 'years', 'concept_id': 'C0439234', 'confidence': 1.0}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'years', 'concept_id': 'C0439234', 'confidence': 1.0}, {'entity': 'original', 'concept_id': 'C0205313', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'Metastases', 'concept_id': 'C0027627', 'confidence': 1.0}, {'entity': 'lung', 'concept_id': 'C0024109', 'confidence': 1.0}, {'entity': 'pleura', 'concept_id': 'C0032225', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_272",
"caption_rating": "8"
},
{
"": "1004347",
"caption": "CD20 IHC is strongly positive, indicating non-Hodgkin lymphoma, possibly diffuse large B cell type.",
"image_path": "r7OA0Trj5hQ_image_e6327955-a8bf-4ccc-b799-cbf285df55ce.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['poorly differentiated cells', 'lamina propria', 'lymphoma', 'CD20 IHC positive', 'poorly differentiated cells', 'lamina propria', 'lymphoma', 'CD20 IHC positive']",
"noisy_text": " Here, what is happening? Very poorly differentiated cells, high grade malignancy. Again, definitely, it is proliferative disease with the ATP. Again, invasion metastasis, we cannot see from this picture. But whenever you see this much of poorly differentiated cells in the gastric biopsy or in the colonic biopsy, and predominantly the atypical cells are situated in the lamina propria, think of lymphoma. This is a CD20 IHC, strongly positive. So this is a non-Hodgkin's lymphoma, possibly diffuse large B cell type. So we are done with surface epithelium. We are done",
"corrected_text": " Here, what is happening? Very poorly differentiated cells, high grade malignancy. Again, definitely, it is proliferative disease with the ATP. Again, invasion metastasis, we cannot see from this picture. But whenever you see this much of poorly differentiated cells in the gastric biopsy or in the colonic biopsy, and predominantly the atypical cells are situated in the lamina propria, think of lymphoma. This is a CD20 IHC, strongly positive. So this is a non-Hodgkin's lymphoma, possibly diffuse large B cell type. So we are done with surface epithelium. We are done",
"med_umls_ids": "[[{'entity': 'Poorly differentiated cells', 'concept_id': 'C0205617', 'confidence': 0.9036805629730225}, {'entity': 'lymphoma', 'concept_id': 'C0024299', 'confidence': 1.0}], [{'entity': 'CD20', 'concept_id': 'C1417326', 'confidence': 1.0}, {'entity': 'IHC', 'concept_id': 'C0021044', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'non-Hodgkin lymphoma', 'concept_id': 'C0024305', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_273",
"caption_rating": "9"
},
{
"": "1004311",
"caption": "The narrator mentions cellular intramuscular myxoma and the challenges in differentiating it from fibrous and more cellular areas.",
"image_path": "QDb68_G1HR4_image_72696061-bdf2-437c-a2ee-0049bbeeccaa.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['myxoid features', 'fine delicate collagen', 'cellular intramuscular myxoma', 'fibrous areas', 'cellular areas', 'MUC4 stain']",
"noisy_text": " Here's again the myxoid background I really think this is very helpful. The very very fine delicate collagen that you see. Now areas like this I think can kind of resemble what you see in a so-called cellular intramuscular myxoma. Intramuscular myxomas are usually very blue and myxoid very hypocellular but sometimes they get more fibrous and more cellular areas. And on a needle biopsy I think that can be challenging. So I think usually with some experience you can tell them apart on H and E most of the time but when I have any doubt I just do a MUC4 stain. The MUC4 is negative and on a needle it looks like a myxoma with some kind of fibrous or a little bit more cellular areas and then I just say that it's probably a cellular intramuscular myxoma. So I think MUC4",
"corrected_text": " Here's again the myxoid background I really think this is very helpful. The very very fine delicate collagen that you see. Now areas like this I think can kind of resemble what you see in a so-called cellular intramuscular myxoma. Intramuscular myxomas are usually very blue and myxoid very hypocellular but sometimes they get more fibrous and more cellular areas. And on a needle biopsy I think that can be challenging. So I think usually with some experience you can tell them apart on H and E most of the time but when I have any doubt I just do a MUC4 stain. The MUC4 is negative and on a needle it looks like a myxoma with some kind of fibrous or a little bit more cellular areas and then I just say that it's probably a cellular intramuscular myxoma. So I think MUC4",
"med_umls_ids": "[[{'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'myxoid', 'concept_id': 'C0205295', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}], [{'entity': 'narrator', 'concept_id': 'C1135957', 'confidence': 0.7711340188980103}, {'entity': 'cellular', 'concept_id': 'C0007634', 'confidence': 0.9999999403953552}, {'entity': 'intramuscular', 'concept_id': 'C0442117', 'confidence': 1.0}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}, {'entity': 'cellular areas', 'concept_id': 'C0007634', 'confidence': 0.7882957458496094}], [{'entity': 'MUC4', 'concept_id': 'C1417496', 'confidence': 0.9999999403953552}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'confirm', 'concept_id': 'C0521093', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'cellular intramuscular myxoma', 'concept_id': 'C1334260', 'confidence': 0.8910117149353027}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_274",
"caption_rating": "7"
},
{
"": "1005239",
"caption": "Explanation of different nuclear patterns seen on histology slides, including monomorphic nuclei where all nuclei appear similar to each other.",
"image_path": "Wiyo6taYRF4_image_136f5416-06d5-4fa2-8dab-0fb003f57369.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Hematopathology', 'Neuropathology', 'Cytopathology']",
"roi_text": "[]",
"noisy_text": " Now, once we have understood the staining pattern of the nuclei, we should also understand what are the different nuclear patterns that we will see on the histology slide. So there are two patterns that are usually described. One is called as monomorphic nuclei. So monomorphic means when all the nuclei, they appear relatively similar to each other. So if the nuclei, they're looking similar to each other, then we will say that the nuclei are monomorphic. And like in this case, you have all the nuclei which are looking",
"corrected_text": " Now, once we have understood the staining pattern of the nuclei, we should also understand what are the different nuclear patterns that we will see on the histology slide. So there are two patterns that are usually described. One is called as monomorphic nuclei. So monomorphic means when all the nuclei, they appear relatively similar to each other. So if the nuclei, they're looking similar to each other, then we will say that the nuclei are monomorphic. And like in this case, you have all the nuclei which are looking",
"med_umls_ids": "[[{'entity': 'Explanation', 'concept_id': 'C0681841', 'confidence': 0.9999998807907104}, {'entity': 'nuclear patterns', 'concept_id': 'C0449774', 'confidence': 0.7514219284057617}, {'entity': 'histology', 'concept_id': 'C0019638', 'confidence': 1.0}, {'entity': 'slides', 'concept_id': 'C0444330', 'confidence': 1.0}, {'entity': 'monomorphic nuclei', 'concept_id': 'C0205649', 'confidence': 0.61530601978302}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1152.0",
"id": "test_275",
"caption_rating": "7"
},
{
"": "1006048",
"caption": "Description of a large punch biopsy with an infiltrate filling the dermis and extending into the subcutaneous tissue.",
"image_path": "8S4LeiO6Bbk_image_02e79690-5b3a-4acd-b1f7-045efdd9787d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['infiltrate filling the dermis and extending into the subcutaneous tissue', 'brown pigment near the surface', 'hyperplastic epidermis', 'cellular infiltrate throughout the dermis', 'infiltrate filling the dermis and extending into the subcutaneous tissue', 'brown pigment near the surface', 'hyperplastic epidermis', 'cellular infiltrate throughout the dermis']",
"noisy_text": " a large punch biopsy. And I think this actually was two punch biopsies from one lesion, each one bisected. And we can see that we've got an infiltrate filling the dermis and extending into the subcutaneous tissue. The infiltrate appears to be compressing the fat rather than growing in between the adipocytes. And I think it's scanning magnification, you know, one of the things that you can really begin to appreciate, not only the fact that this lesion is partially sampled, that it extends to the base and edges of the specimen, but one can begin to appreciate abundant hemorrhage within this tumor. And in addition, we can see some brown pigment near the surface. And common sense will tell you where there's smoke, there's fire. Since we do have all this abundant hemorrhage, there's a high probability that the pigment, this brownish gold pigment that we're seeing up near the surface of the specimen is likely hemocentaurant rather than melanin. But we'll confirm that when we go down to a higher power. As we move in, we can see that the epidermis is slightly hyperplastic. We've got this cellular infiltrate throughout the dermis and we'll need to go down and take a look at this infiltrate. It appears a little less dense at the",
"corrected_text": " a large punch biopsy. And I think this actually was two punch biopsies from one lesion, each one bisected. And we can see that we've got an infiltrate filling the dermis and extending into the subcutaneous tissue. The infiltrate appears to be compressing the fat rather than growing in between the adipocytes. And I think it's scanning magnification, you know, one of the things that you can really begin to appreciate, not only the fact that this lesion is partially sampled, that it extends to the base and edges of the specimen, but one can begin to appreciate abundant hemorrhage within this tumor. And in addition, we can see some brown pigment near the surface. And common sense will tell you where there's smoke, there's fire. Since we do have all this abundant hemorrhage, there's a high probability that the pigment, this brownish gold pigment that we're seeing up near the surface of the specimen is likely hemocentaurant rather than melanin. But we'confirm that when we go down to a higher power. As we move in, we can see that the epidermis is slightly hyperplastic. We've got this cellular infiltrate throughout the dermis and we'll need to go down and take a look at this infiltrate. It appears a little less dense at the",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'punch biopsy', 'concept_id': 'C0182557', 'confidence': 1.0}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'filling', 'concept_id': 'C0178866', 'confidence': 0.7777882218360901}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'subcutaneous tissue', 'concept_id': 'C0222331', 'confidence': 1.0}], [{'entity': 'Excessive', 'concept_id': 'C0442802', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'brown pigment near', 'concept_id': 'C4555503', 'confidence': 0.865685760974884}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}], [{'entity': 'hyperplastic epidermis', 'concept_id': 'C4748317', 'confidence': 0.7633129358291626}, {'entity': 'cellular infiltrate', 'concept_id': 'C1692321', 'confidence': 1.0}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_276",
"caption_rating": "9"
},
{
"": "1004747",
"caption": "Presence of lymphocytes and hints of duct formation within the tumor.",
"image_path": "8S4LeiO6Bbk_image_d28d47c0-0566-471c-9383-713c820a78ef.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['epithelial tumor', 'cytoplasm', 'vesicular chromatin pattern', 'lymphocytes', 'duct formation']",
"noisy_text": " If we move to higher power, we can see that we're dealing with an epithelial rather than a mosaicable tumor. We've got interconnected cords and strands. We have somewhat of a ribiform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of the cells are round to oval. They're fairly large. These cells have some faint eosinophilic to pale gray cytoplasm, although this cytoplasm is kind of difficult to see. Some of these cells have an evenly dispersed or vesicular chromatin pattern, and other nuclei are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and",
"corrected_text": " If we move to higher power, we can see that we're dealing with an epithelial rather than a mesenchymal tumor. We've got interconnected cords and strands. We have somewhat of a cribriform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of the cells are round to oval. They're fairly large. These cells have some faint eosinophilic to pale gray cytoplasm, although this cytoplasm is kind of difficult to see. Some of these cells have an evenly dispersed or vesicular chromatin pattern, and other nuclei are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'epithelial tumor', 'concept_id': 'C1368683', 'confidence': 0.9999999403953552}, {'entity': 'cords', 'concept_id': 'C0034869', 'confidence': 0.801885187625885}, {'entity': 'strands', 'concept_id': 'C0600383', 'confidence': 0.800572395324707}], [{'entity': 'Cribriform pattern', 'concept_id': 'C1333163', 'confidence': 1.0}, {'entity': 'loose', 'concept_id': 'C0205407', 'confidence': 1.0}, {'entity': 'edematous', 'concept_id': 'C0013604', 'confidence': 1.0}, {'entity': 'vascular stroma', 'concept_id': 'C0005847', 'confidence': 0.8046398758888245}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'cell types', 'concept_id': 'C0007634', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'eosinophilic', 'concept_id': 'C0333930', 'confidence': 1.0}, {'entity': 'pale', 'concept_id': 'C0030232', 'confidence': 1.0}, {'entity': 'gray cytoplasm', 'concept_id': 'C0010834', 'confidence': 0.8177905678749084}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'duct', 'concept_id': 'C0687028', 'confidence': 1.0}, {'entity': 'formation', 'concept_id': 'C0220781', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_277",
"caption_rating": "8"
},
{
"": "1008702",
"caption": "The diagnosis in this case is a rudimentary supernumerary digit.",
"image_path": "8S4LeiO6Bbk_image_d73237ea-0389-4d09-a0bf-a7cf76772156.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['dome-shaped papule', 'acral site', 'thick stratum corneum', 'absence of hair follicles', 'fibrovascular core', 'nerve fascicles', 'spindle-shaped cells', 'S100', 'SOX10', 'rudimentary supernumerary digit', 'dome-shaped papule', 'acral site', 'thick stratum corneum', 'absence of hair follicles', 'fibrovascular core', 'nerve fascicles', 'spindle-shaped cells', 'S100', 'SOX10', 'rudimentary supernumerary digit']",
"noisy_text": " we've got a dome-shaped papule and that the biopsy is from an acral site. Notice that we've got a very very thick stratum corneum and a marked to virtual absence of hair follicles within the specimen. We do have kind of this fibrovascular core and of course in the center of the fibrovascular core here we've got several well-defined nerve fascicles and the spindled cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions",
"corrected_text": " we've got a dome-shaped papule and that the biopsy is from an acral site. Notice that we've got a very very thick stratum corneum and a marked to virtual absence of hair follicles within the specimen. We do have kind of this fibrovascular core and of course in the center of the fibrovascular core here we've got several well-defined nerve fascicles and the spindle cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions",
"med_umls_ids": "[[{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'acral site', 'concept_id': 'C0439746', 'confidence': 0.717435359954834}, {'entity': 'dome-shaped papule', 'concept_id': 'C1711316', 'confidence': 0.752353847026825}], [{'entity': 'specimen', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'stratum corneum', 'concept_id': 'C0221921', 'confidence': 1.0}, {'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'hair follicles', 'concept_id': 'C0221971', 'confidence': 0.9999998807907104}], [{'entity': 'fibrovascular', 'concept_id': 'C0392759', 'confidence': 1.0}, {'entity': 'nerve fascicles', 'concept_id': 'C1185741', 'confidence': 0.8332967758178711}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'S100', 'concept_id': 'C3273837', 'confidence': 1.0}, {'entity': 'SOX10', 'concept_id': 'C1420317', 'confidence': 0.9999998807907104}, {'entity': 'neural tumor', 'concept_id': 'C1334956', 'confidence': 1.0}], [{'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'rudimentary supernumerary digit', 'concept_id': 'C0152427', 'confidence': 0.8142021894454956}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_278",
"caption_rating": "8"
},
{
"": "1007632",
"caption": "Combined melanocytic nevus with features of both a common or benign nevus and a blue nevus.",
"image_path": "8S4LeiO6Bbk_image_359fb1b6-fa83-4703-974b-2bbcc5a627f0.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Dendritic and spindle-shaped melanocytes', 'Heavily pigmented melanophages', 'Sclerotic stroma', 'Combined melanocytic nevus with features of common/benign nevus and blue nevus', 'Dendritic and spindle-shaped melanocytes']",
"noisy_text": " or fusiform-shaped nuclei. They're arranged in short, intersecting vascals. And in between the dendritic and spindled melanocytes, we have very heavily pigmented melanovagias, all set in a sclerotic stroma. So basically, we have here a combined melanocytic nevus, one that has features of both a common or banal nevus and a blue nevus. And this is amongst the most common type of combined melanocytic nevus. By definition, a combined melanocytic nevus has at least two, sometimes more, distinct clonal populations of melanocytes that have a different morphology. And sometimes this is referred to as a true blue nevus because it's a true nevus or a banal nevus and a blue nevus. But it's possible to have all kinds of combinations. We can get a blue nevus with a spitz nevus. We can get balloon cell nevi. Those are combined nevi because you usually have a population of banal appearing melanocytes and balloon melanocytes. At that point, inactivated melanocytic tumors are frequently combined nevi, commonly characterized by banal nevus and a population of very epithelial spits like melanocytes. So anyway, all possible combinations are... And in actuality, a deep penetrating nevus is frequently combined nevus with a combination of banal nevus and what looks oftentimes like a cellular blue nevus. So anyway, this is a combined melanocytic nevus.",
"corrected_text": " or fusiform-shaped nuclei. They're arranged in short, intersecting vessels. And in between the dendritic and spindled melanocytes, we have very heavily pigmented melanophages, all set in a sclerotic stroma. So basically, we have here a combined melanocytic nevus, one that has features of both a common or banal nevus and a blue nevus. And this is amongst the most common type of combined melanocytic nevus. By definition, a combined melanocytic nevus has at least two, sometimes more, distinct clonal populations of melanocytes that have a different morphology. And sometimes this is referred to as a true blue nevus because it's a true nevus or a banal nevus and a blue nevus. But it's possible to have all kinds of combinations. We can get a blue nevus with a spitz nevus. We can get balloon cell nevi. Those are combined nevi because you usually have a population of banal appearing melanocytes and balloon melanocytes. At that point, inactivated melanocytic tumors are frequently combined nevi, commonly characterized by banal nevus and a population of very epithelial spits like melanocytes. So anyway, all possible combinations are... And in actuality, a deep penetrating nevus is frequently combined nevus with a combination of banal nevus and what looks oftentimes like a cellular blue nevus. So anyway, this is a combined melanocytic nevus.",
"med_umls_ids": "[[{'entity': 'Combined', 'concept_id': 'C0205195', 'confidence': 1.0}, {'entity': 'melanocytic nevus', 'concept_id': 'C0027962', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'benign nevus', 'concept_id': 'C1456781', 'confidence': 1.0}, {'entity': 'blue nevus', 'concept_id': 'C0206736', 'confidence': 1.0}], [{'entity': 'Contains', 'concept_id': 'C0332256', 'confidence': 0.9999999403953552}, {'entity': 'clonal populations', 'concept_id': 'C0032659', 'confidence': 0.8110582232475281}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}], [{'entity': 'combinations', 'concept_id': 'C0453882', 'confidence': 1.0}, {'entity': 'combined', 'concept_id': 'C0205195', 'confidence': 1.0}, {'entity': 'nevi', 'concept_id': 'C0027960', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_279",
"caption_rating": "9"
},
{
"": "1004181",
"caption": "Neutrophils in the epithelium indicate cryptitis, which may be related to H. pylori infection.",
"image_path": "r7OA0Trj5hQ_image_7357e616-a846-495b-9c61-7830aeba911b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Neutrophils in the epithelium indicating cryptitis', 'Gastric biopsy for H. pylori with crypt abscess']",
"noisy_text": " Please remember, presence of lymphocytes and plasma cells is not a feature of chronicity. But architectural change by the way of irregular size, shape, and distributed glands is an indication of chronicity. Criteria for chronicity. Yeah, you see nicely neutrophils sitting in the epithelium. Can you all see neutrophils sitting in the epithelium? So this is cryptitis. It is stomach, even though I'm using the term. But I just want to know whether you are able to understand or not. This is a gastric biopsy where you have to look for H. pylori because the H. pylori secrete some chemotactic factors for neutrophils. That's why the neutrophils come. And this is a crypt abscess. This is",
"corrected_text": " Please remember, presence of lymphocytes and plasma cells is not a feature of chronicity. But architectural change by the way of irregular size, shape, and distributed glands is an indication of chronicity. Criteria for chronicity. Yeah, you see nicely neutrophils sitting in the epithelium. Can you all see neutrophils sitting in the epithelium? So this is cryptitis. It is stomach, even though I'm using the term. But I just want to know whether you are able to understand or not. This is a gastric biopsy where you have to look for H. pylori because the H. pylori secrete some chemotactic factors for neutrophils. That's why the neutrophils come. And this is a crypt abscess. This is",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'chronicity', 'concept_id': 'C0547045', 'confidence': 1.0}, {'entity': 'architectural', 'concept_id': 'C0003737', 'confidence': 0.8758222460746765}, {'entity': 'changes', 'concept_id': 'C0392747', 'confidence': 1.0}, {'entity': 'gland size', 'concept_id': 'C0426336', 'confidence': 0.8790121674537659}, {'entity': 'shape', 'concept_id': 'C0332479', 'confidence': 1.0}, {'entity': 'distribution', 'concept_id': 'C0037775', 'confidence': 1.0}, {'entity': 'chronicity', 'concept_id': 'C0547045', 'confidence': 1.0}], [{'entity': 'Neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'cryptitis', 'concept_id': 'C1394254', 'confidence': 0.9999998807907104}, {'entity': 'H. pylori infection', 'concept_id': 'C0850666', 'confidence': 0.9999999403953552}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_280",
"caption_rating": "8"
},
{
"": "1006217",
"caption": "Comparison of squamous morphology of MAC with desmoplastic tricholemmoma or syringoma.",
"image_path": "LlPaENuqzVQ_image_e65482d5-11ca-44e7-a128-fd8c780345dd.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['Eosinophilic cells with squamous morphology', 'Fibromyxoid stroma', 'Diffuse dissection throughout the dermis']",
"noisy_text": " We have a diagnosis called the surface of the sclerosing epithelial neoplasm. You have to go back and take more, another biopsy. MACs often will have a little more squamoid morphology like this. Can you see those kind of eosinophilic cells? They kind of look a little bit more like squamous cells a little bit. So that favors MAC more than like a desmoplastic tricho or even like a serendoma. A serendoma usually also is obviously much smaller. You can't take a shave biopsy and get an entire serendoma out. And usually the stroma is more prominent in the serendoma. Notice that this stroma is more fibromucinous. So this thing is kind of dissecting diffusely throughout the dermis here. I don't see",
"corrected_text": " We have a diagnosis called the surface of the sclerosing epithelial neoplasm. You have to go back and take more, another biopsy. MACs often will have a little more squamous morphology like this. Can you see those kind of eosinophilic cells? They kind of look a little bit more like squamous cells a little bit. So that favors MAC more than like a desmoplastic tricholemmoma or even like a syringoma. A syringoma usually also is obviously much smaller. You can't take a shave biopsy and get an entire syringoma out. And usually the stroma is more prominent in the syringoma. Notice that this stroma is more fibromyxoid. So this thing is kind of dissecting diffusely throughout the dermis here. I don't see",
"med_umls_ids": "[[{'entity': 'Diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'sclerosing', 'concept_id': 'C0036426', 'confidence': 0.833010733127594}, {'entity': 'epithelial neoplasm', 'concept_id': 'C1368683', 'confidence': 1.0}, {'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}], [{'entity': 'Comparison', 'concept_id': 'C1707455', 'confidence': 1.0}, {'entity': 'squamous', 'concept_id': 'C1182670', 'confidence': 0.9999998807907104}, {'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}, {'entity': 'MAC', 'concept_id': 'C0009545', 'confidence': 0.9999999403953552}, {'entity': 'desmoplastic tricholemmoma', 'concept_id': 'C1275206', 'confidence': 0.9999999403953552}, {'entity': 'syringoma', 'concept_id': 'C0206673', 'confidence': 1.0}], [{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'fibromyxoid', 'concept_id': 'C0205766', 'confidence': 0.8987292051315308}, {'entity': 'stroma', 'concept_id': 'C0927195', 'confidence': 1.0}, {'entity': 'diffuse dissection', 'concept_id': 'C0205219', 'confidence': 0.7718934416770935}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_281",
"caption_rating": "7"
},
{
"": "1006861",
"caption": "Architectural distortion, prominent lymphoid aggregates, and Paneth cell metaplasia may indicate inflammatory bowel disease or diversion colitis.",
"image_path": "sDFjOtMAYrk_image_d2c14566-c857-49e5-9213-ae46e036c9ef.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['Architectural distortion', 'Prominent lymphoid aggregates', 'Paneth cell metaplasia']",
"noisy_text": " architectural distortion, prominent lymphoid aggregates and pan-at-cell metaplasia, C-note in the absence of any history, the differential diagnosis includes, you know, inflammatory bowel disease, com parenthesis quiescent, comma. I mean, because of the lymphoid aggregates, I would think about diversion colitis, knowing that this is from the rectum, even if I don't know that the patient has a Hartman's pouch. I would say infection is unlikely and medication probably unlikely. And for the first case, let's, sometimes we get the condition that give you just random colon and not have this. Just on the one, just on the one biopsy. Yeah. And then",
"corrected_text": " architectural distortion, prominent lymphoid aggregates and paneth cell metaplasia, note in the absence of any history, the differential diagnosis includes, you know, inflammatory bowel disease, com parenthesis quiescent, comma. I mean, because of the lymphoid aggregates, I would think about diversion colitis, knowing that this is from the rectum, even if I don't know that the patient has a Hartman's pouch. I would say infection is unlikely and medication probably unlikely. And for the first case, let's, sometimes we get the condition that give you just random colon and not have this. Just on the one, just on the one biopsy. Yeah. And then",
"med_umls_ids": "[[{'entity': 'Architectural distortion', 'concept_id': 'C2826609', 'confidence': 1.0}, {'entity': 'lymphoid', 'concept_id': 'C1518071', 'confidence': 1.0}, {'entity': 'aggregates', 'concept_id': 'C0205418', 'confidence': 1.0}, {'entity': 'Paneth', 'concept_id': 'C0227276', 'confidence': 0.7872004508972168}, {'entity': 'inflammatory bowel disease', 'concept_id': 'C0021390', 'confidence': 1.0}, {'entity': 'diversion colitis', 'concept_id': 'C0267532', 'confidence': 1.0}], [{'entity': 'Infection', 'concept_id': 'C0009450', 'confidence': 1.0}, {'entity': 'medication', 'concept_id': 'C0013227', 'confidence': 1.0}], [{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lymphoid', 'concept_id': 'C1518071', 'confidence': 1.0}, {'entity': 'aggregates', 'concept_id': 'C0205418', 'confidence': 1.0}, {'entity': 'diversion colitis', 'concept_id': 'C0267532', 'confidence': 1.0}, {'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'Hartman\u2019s pouch', 'concept_id': 'C0447546', 'confidence': 0.9055206179618835}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_282",
"caption_rating": "9"
},
{
"": "1008745",
"caption": "Nodular infiltrate in the dermis with clear spaces centrally and darker staining cells at the periphery.",
"image_path": "hoV-JkD6Wb0_image_f1801b51-f6e9-4f7c-903c-1448201290c2.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['epithelial metaplasia', 'epithelial hyperplasia', 'nodular infiltrate', 'clear spaces', 'lymphocytes', 'plasma cells', 'epithelial metaplasia', 'epithelial hyperplasia', 'nodular infiltrate', 'clear spaces', 'lymphocytes', 'plasma cells']",
"noisy_text": " from this lesion that hopefully you had a chance to look at, quadricected shade biopsy. And one can see quite a bit of epithelial, pseudoepithelial metacyproplasia, epithelial hyperplasia. I think I'm going to flip the slide and look at the top piece in the dermis. And one can see we have a nodular infiltrate in the dermis, lots and lots of clear spaces centrally, and then some darker staining cells out at the periphery. And out at the periphery, we have a lot of lymphocytes and several scattered plasma cells. And if we look at the more clear staining areas, we can",
"corrected_text": " from this lesion that hopefully you had a chance to look at, excisional biopsy. And one can see quite a bit of epithelial, pseudoepithelial metaplasia, epithelial hyperplasia. I think I'm going to flip the slide and look at the top piece in the dermis. And one can see we have a nodular infiltrate in the dermis, lots and lots of clear spaces centrally, and then some darker staining cells out at the periphery. And out at the periphery, we have a lot of lymphocytes and several scattered plasma cells. And if we look at the more clear staining areas, we can",
"med_umls_ids": "[[{'entity': 'Epithelial', 'concept_id': 'C0221908', 'confidence': 1.0}, {'entity': 'pseudoepithelial metaplasia', 'concept_id': 'C1317977', 'confidence': 0.7813463807106018}, {'entity': 'hyperplasia', 'concept_id': 'C0020507', 'confidence': 1.0}, {'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}], [{'entity': 'Nodular infiltrate', 'concept_id': 'C0241130', 'confidence': 0.840809166431427}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'centrally', 'concept_id': 'C0205099', 'confidence': 0.7070305943489075}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'scattered', 'concept_id': 'C0439742', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_283",
"caption_rating": "8"
},
{
"": "1005865",
"caption": "The narrator is discussing low-grade and high-grade dysplasia and pointing out the differences in glandular architecture, specifically the presence or absence of stroma between glands.",
"image_path": "r7OA0Trj5hQ_image_86336143-b38a-4f77-8964-9f24c07a1c0d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Cribriform intraglandular pattern.', 'Cribriform intraglandular pattern.']",
"noisy_text": " with the low-grade and the high-grade dysplasia. This is a beautiful picture I got it from the Google where it looks normal here. Low-grade dysplastic changes here and the high-grade dysplastic changes here. See the cribriform. Why they are not back-to-back glands? When it is back-to-back glands, you can see some stroma running in between. However, it may be crowded. See here, one gland, another gland. You can see the nice stroma in between. These are back-to-back glands. But see here, this is one gland, this is one gland, this is one gland. But no stroma in between. So these are cribriform, which is intraglandular. Epithelial proliferation",
"corrected_text": " with the low-grade and the high-grade dysplasia. This is a beautiful picture I got it from the Google where it looks normal here. low-grade dysplasia here and the high-grade dysplasia here. See the cribriform. Why they are not back-to-back glands? When it is back-to-back glands, you can see some stroma running in between. However, it may be crowded. See here, one gland, another gland. You can see the nice stroma in between. These are back-to-back glands. But see here, this is one gland, this is one gland, this is one gland. But no stroma in between. So these are cribriform, which is intraglandular. Epithelial proliferation",
"med_umls_ids": "[[{'entity': 'narrator', 'concept_id': 'C1135957', 'confidence': 0.7711340188980103}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'high-grade dysplasia', 'concept_id': 'C1333110', 'confidence': 0.8831341862678528}, {'entity': 'differences', 'concept_id': 'C1705241', 'confidence': 0.9019047021865845}, {'entity': 'glandular architecture', 'concept_id': 'C1710057', 'confidence': 0.8609142303466797}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'stroma', 'concept_id': 'C0927195', 'confidence': 1.0}, {'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_284",
"caption_rating": "8"
},
{
"": "1007913",
"caption": "The tissue sample contains nail bed and matrix epithelium.",
"image_path": "8S4LeiO6Bbk_image_d5b1b003-cbe4-408e-815b-f0a4aa81b2b9.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['nail bed', 'matrix epithelium', 'melanocytes forming nests', 'pagetoid pattern', 'basal layer of the matrix', 'upper portions of the matrix', 'nail bed', 'matrix epithelium', 'melanocytes forming nests', 'pagetoid pattern', 'basal layer of the matrix', 'upper portions of the matrix']",
"noisy_text": " we've got nail bed and matricle epithelium. I believe this must be some nail fold, a portion of the nail fold, and then in the bottom piece of tissue in these sections we actually have matricle epithelium and you can see the rete or somewhat hyperplastic. And on higher power examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matricle epithelium in the matricle layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that",
"corrected_text": " we've got nail bed and matrix epithelium. I believe this must be some nail fold, a portion of the nail fold, and then in the bottom piece of tissue in these sections we actually have matrix epithelium and you can see the rete or somewhat hyperplastic. And on higher power examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matrix epithelium in the matrix layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that",
"med_umls_ids": "[[{'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'nail', 'concept_id': 'C0027342', 'confidence': 1.0}, {'entity': 'matrix epithelium', 'concept_id': 'C0014609', 'confidence': 0.7584323883056641}], [{'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'nests', 'concept_id': 'C0035253', 'confidence': 0.7275967001914978}, {'entity': 'upper portions', 'concept_id': 'C0449719', 'confidence': 0.6251541972160339}, {'entity': 'matrix', 'concept_id': 'C0331858', 'confidence': 1.0}, {'entity': 'pagetoid', 'concept_id': 'C1518847', 'confidence': 0.8801172375679016}, {'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}], [{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'matrix layer', 'concept_id': 'C0331858', 'confidence': 0.71736741065979}, {'entity': 'suspicious', 'concept_id': 'C0750493', 'confidence': 1.0}, {'entity': 'melanoma', 'concept_id': 'C0025202', 'confidence': 1.0}, {'entity': 'in situ', 'concept_id': 'C0444498', 'confidence': 0.9999999403953552}]]",
"magnification": "1.0",
"height": "758.0",
"width": "1920.0",
"id": "test_285",
"caption_rating": "8"
},
{
"": "1006254",
"caption": "This type of tumor does not exhibit perineural invasion.",
"image_path": "LlPaENuqzVQ_image_0ef0792c-d1b8-4de0-a1fd-16a0557d2051.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['desmoplastic tricholemmomaphthelioma', 'calcification', 'perineural invasion', 'cleft between the stroma and the epithelium']",
"noisy_text": " There may be some little small duct-like structures at the top of the calcification. This is a desmoplastic trichophthelioma. It's different than a MAC. So it's got a different morphology. It's got the calcification and different stroma. These do not get neurotropic involvement. So, and you know, this is a definitive diagnosis here also. We don't need to stain this or anything. We would diagnose this as a desmoplastic MAC or a microcystic or a desmoplastic tricho and then just move on to the next case. It's different than MAC. It's different than basal cell. It doesn't have the clest between the stroma and the epithelium here. Okay, so",
"corrected_text": " There may be some little small duct-like structures at the top of the calcification. This is a desmoplastic trichoepithelioma. It's different than a MAC. So it's got a different morphology. It's got the calcification and different stroma. These do not get neurotropic involvement. So, and you know, this is a definitive diagnosis here also. We don't need to stain this or anything. We would diagnose this as a desmoplastic MAC or a microcystic or a desmoplastic tricho and then just move on to the next case. It's different than MAC. It's different than basal cell. It doesn't have the cleft between the stroma and the epithelium here. Okay, so",
"med_umls_ids": "[[{'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'desmoplastic tricholemmomaphthelioma', 'concept_id': 'C1275206', 'confidence': 0.8335589170455933}, {'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}, {'entity': 'stroma', 'concept_id': 'C0927195', 'confidence': 1.0}, {'entity': 'MAC', 'concept_id': 'C0009545', 'confidence': 0.9999999403953552}], [{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'perineural invasion', 'concept_id': 'C1317608', 'confidence': 1.0}], [{'entity': 'duct-like structures', 'concept_id': 'C1880423', 'confidence': 0.9012507796287537}, {'entity': 'calcification', 'concept_id': 'C0006660', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_286",
"caption_rating": "7"
},
{
"": "1006184",
"caption": "Description of a cocktail of markers used for intraductal carcinoma of the prostate diagnosis.",
"image_path": "iklRyY1nBIE_image_f98d30b9-5304-4210-b9f8-92fc429a8533.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['basal cells at the periphery', 'enlarged nuclei', 'intraductal carcinoma of the prostate', 'adjacent invasive tumor', 'previously benign gland', 'basal cells at the periphery', 'enlarged nuclei', 'intraductal carcinoma of the prostate', 'adjacent invasive tumor', 'previously benign gland']",
"noisy_text": " Let me show you what the cocktail looks like. Again, this is the pin three, or some call it pin four. You have the P63, you have the hemoglobin cytokeratin, and then you have the racemase, which is the pink chromogen. And as you can see, as I demonstrated on the H&E, basal cells are indeed present. This is too much for high-grade pin. This is basically what is called a solid cribriform kind of pattern, in which over 50% of the lumen is filled by tumor cells. So this is way too much for high-grade pin. But it's not invasive, because you have basal cells at the periphery. And the nuclei are enlarged. These nuclei are about six times the size of normal prostate nuclei. So this case meets the criteria for introductal carcinoma of the prostate. There is an invasive component, which you can see is negative for basal cell markers. But you have the introductal component. And this is a very interesting entity. The vast majority of cases, and I'll show you the corresponding radical prostatectomy specimens in a second, but the vast majority of these so-called introductal carcinoma of the prostate is due to invasion, colonization by adjacent invasive tumor. And it usually occurs in patients that have high-volume tumors. When I show you the corresponding radical prostatectomies, you'll see what I'm talking about. You usually don't have this in patients in their radicals that have 5% prostate cancer or 10% prostate cancer. It's usually patients that have extensive prostate cancer involvement, and the invasive glands basically have nowhere else to go but to colonize adjacent benign glands. And I'll demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues,",
"corrected_text": " Let me show you what the cocktail looks like. Again, this is the pin three, or some call it pin four. You have the P63, you have the hemoglobin cytokeratin, and then you have the racemase, which is the AMACR. And as you can see, as I demonstrated on the H&E, basal cells are indeed present. This is too much for high-grade pin. This is basically what is called a solid cribriform kind of pattern, in which over 50% of the lumen is filled by tumor cells. So this is way too much for high-grade pin. But it's not invasive, because you have basal cells at the periphery. And the nuclei are enlarged. These nuclei are about six times the size of normal prostate nuclei. So this case meets the criteria for intraductal carcinoma of the prostate. There is an invasive component, which you can see is negative for basal cell markers. But you have the intraductal component. And this is a very interesting entity. The vast majority of cases, and I'll show you the corresponding radical prostatectomy specimens in a second, but the vast majority of these so-called intraductal carcinoma of the prostate is due to invasion, colonization by adjacent invasive tumor. And it usually occurs in patients that have high-volume tumors. When I show you the corresponding radical prostatectomies, you'll see what I'm talking about. You usually don't have this in patients in their radicals that have 5% prostate cancer or 10% prostate cancer. It's usually patients that have extensive prostate cancer involvement, and the invasive glands basically have nowhere else to go but to colonize adjacent benign glands. And I'demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues,",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'cocktail', 'concept_id': 'C0678420', 'confidence': 1.0}, {'entity': 'markers', 'concept_id': 'C0181734', 'confidence': 0.890313982963562}, {'entity': 'intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate diagnosis', 'concept_id': 'C0011900', 'confidence': 0.7927443981170654}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'basal cells', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}], [{'entity': 'Enlarged nuclei', 'concept_id': 'C4013177', 'confidence': 0.7774685621261597}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'normal', 'concept_id': 'C0205307', 'confidence': 1.0}], [{'entity': 'Intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'invasion', 'concept_id': 'C1269955', 'confidence': 1.0}, {'entity': 'colonization', 'concept_id': 'C4289767', 'confidence': 1.0}, {'entity': 'adjacent', 'concept_id': 'C0205117', 'confidence': 1.0}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}], [{'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'benign gland', 'concept_id': 'C0205183', 'confidence': 0.7986565828323364}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_287",
"caption_rating": "7"
},
{
"": "1005791",
"caption": "Reticular connective tissue is found underneath all epithelial tissue.",
"image_path": "ib991vTA67A_image_16aa5ee3-f5c4-4aca-9da4-3d65198defc4.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Head and Neck']",
"roi_text": "['elastic cartilage', 'lacunas', 'chondrocytes', 'external ear', 'epiglottis', 'reticular connective tissue', 'epithelial tissue']",
"noisy_text": " the answer, this is elastic cartilage, you know it's a cartilage because you see the lacunas, so this is lacuna right here with the chondrocyte in it, where do you find elastic cartilage, think of the E's, elastic cartilage, external ear and the epiglottis, so elastic cartilage, external ear, epiglottis, that's where you're going to find elastic cartilage, that was number nineteen, number twenty, where do you, see this is a reticular connective tissue again, where do you find it, underneath all epithelial tissue, underneath all epithelial tissue, remember",
"corrected_text": " the answer, this is elastic cartilage, you know it's a cartilage because you see the lacunas, so this is lacuna right here with the chondrocyte in it, where do you find elastic cartilage, think of the E's, elastic cartilage, external ear and the epiglottis, so elastic cartilage, external ear, epiglottis, that's where you're going to find elastic cartilage, that was number nineteen, number twenty, where do you, see this is a reticular connective tissue again, where do you find it, underneath all epithelial tissue, underneath all epithelial tissue, remember",
"med_umls_ids": "[[{'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'examined', 'concept_id': 'C0332128', 'confidence': 1.0}, {'entity': 'elastic cartilage', 'concept_id': 'C0682559', 'confidence': 0.9999998807907104}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lacunas', 'concept_id': 'C1459585', 'confidence': 0.8563621044158936}, {'entity': 'chondrocytes', 'concept_id': 'C0225369', 'confidence': 1.0}], [{'entity': 'Elastic cartilage', 'concept_id': 'C0682559', 'confidence': 0.9999998807907104}, {'entity': 'external ear', 'concept_id': 'C0013453', 'confidence': 1.0}, {'entity': 'epiglottis', 'concept_id': 'C0014540', 'confidence': 0.9999999403953552}], [{'entity': 'Reticular', 'concept_id': 'C0439739', 'confidence': 1.0}, {'entity': 'connective tissue', 'concept_id': 'C0009780', 'confidence': 1.0}, {'entity': 'epithelial tissue', 'concept_id': 'C0014609', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1152.0",
"id": "test_288",
"caption_rating": "7"
},
{
"": "1009451",
"caption": "Nodular infiltrate in the dermis with clear spaces centrally and darker staining cells at the periphery.",
"image_path": "hoV-JkD6Wb0_image_da8f5777-05ab-42a2-aa28-5a3ebba66391.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['nodular infiltrate in the dermis', 'lymphocytes', 'clear spaces centrally', 'plasma cells', 'large histiocytes']",
"noisy_text": " I'm going to flip the slide and look at the top piece in the dermis. And one can see we have a nodular infiltrate in the dermis, lots and lots of clear spaces centrally, and then some darker staining cells out at the periphery. And out at the periphery, we have a lot of lymphocytes and several scattered plasma cells. And if we look at the more clear staining areas, we can see that we actually have very large histiocytes. We've cleared out cytoplasm and with a little effort, one could see that there were organisms present within the cytoplasm of these histiocytes",
"corrected_text": " I'm going to flip the slide and look at the top piece in the dermis. And one can see we have a nodular infiltrate in the dermis, lots and lots of clear spaces centrally, and then some darker staining cells out at the periphery. And out at the periphery, we have a lot of lymphocytes and several scattered plasma cells. And if we look at the more clear staining areas, we can see that we actually have very large histiocytes. We've cleared out cytoplasm and with a little effort, one could see that there were organisms present within the cytoplasm of these histiocytes",
"med_umls_ids": "[[{'entity': 'Nodular infiltrate', 'concept_id': 'C0241130', 'confidence': 0.840809166431427}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'centrally', 'concept_id': 'C0205099', 'confidence': 0.7070305943489075}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'scattered', 'concept_id': 'C0439742', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}], [{'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'organisms', 'concept_id': 'C0029235', 'confidence': 0.9999998807907104}, {'entity': 'cytoplasm', 'concept_id': 'C0010834', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_289",
"caption_rating": "8"
},
{
"": "1009311",
"caption": "Presence of crescent in the Bowman space, which is associated with glomerular nephritis. Peritoneal epithelial hyperpressure can compress the glomerulus.",
"image_path": "WhnEXkBN4D8_image_27eadb3c-ce49-4591-857f-e4fccb4d1353.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Renal', 'Hematopathology', 'Soft tissue']",
"roi_text": "['crescent in the Bowman space', 'peritoneal epithelial hyperpressure compressing the glomerulus', 'crescent in the Bowman space']",
"noisy_text": " But what's happening is, in the Bowman space, something is protruding from the Bowman space, right? You must have definitely read about multiple things in glomerular nephritis. You must have definitely come across something called as a crescent. This is actually the crescent. You won't expect crescent always in the crescentic form. The crescent is something which is going to be there in the Bowman's capsule coming from your membrane, right? If you see this, these are nothing but your peritoneal epithelial hyperpressure coming and compressing the glomeruli. That's one,",
"corrected_text": " But what's happening is, in the Bowman space, something is protruding from the Bowman space, right? You must have definitely read about multiple things in glomerular nephritis. You must have definitely come across something called as a crescent. This is actually the crescent. You won't expect crescent always in the crescentic form. The crescent is something which is going to be there in the Bowman's capsule coming from your membrane, right? If you see this, these are nothing but your peritoneal epithelial hyperpressure coming and compressing the glomeruli. That's one,",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'crescent', 'concept_id': 'C0444628', 'confidence': 1.0}, {'entity': 'Bowman space', 'concept_id': 'C1280145', 'confidence': 0.8839771747589111}, {'entity': 'associated with', 'concept_id': 'C0332281', 'confidence': 1.0}, {'entity': 'glomerular nephritis', 'concept_id': 'C0017658', 'confidence': 1.0}, {'entity': 'Peritoneal', 'concept_id': 'C0031153', 'confidence': 1.0}, {'entity': 'epithelial hyperpressure', 'concept_id': 'C0014599', 'confidence': 0.6601702570915222}, {'entity': 'compress', 'concept_id': 'C0180053', 'confidence': 1.0}, {'entity': 'glomerulus', 'concept_id': 'C0022663', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_290",
"caption_rating": "8"
},
{
"": "1004615",
"caption": "Tuberculoid form of leprosy can cause sarcoid granulomatous inflammation.",
"image_path": "udoW6VSqsm4_image_e51a876a-6b32-4cb6-8b7b-25b3f8e6b479.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['sarcoid granulomatous inflammation', 'involvement around nerves']",
"noisy_text": " That's the tuberculoid. Yeah, good. The tuberculoid form of leprosy gives you sarcoidal granulomatous inflammation. It's elongated. Very good. That's exactly right. What else can give you sarcoidal granulomatous inflammation? Can I ask a quick question about the sarcoid with the two... The nansins? So, I had a case, I saw a case that looked kind of horizontal, but it was sarcoid. And so, what other ways can you tell? Sometimes it can be difficult, but usually you're going to see involvement around nerves damaged nerves. You're about to get sarcoidal granulomatous inflammation. They always have very high risk inflammatory reactions. They just wipe out the nerves. So, that's helpful. Wasn't",
"corrected_text": " That's the tuberculoid. Yeah, good. The tuberculoid form of leprosy gives you sarcoidal granulomatous inflammation. It's elongated. Very good. That's exactly right. What else can give you sarcoidal granulomatous inflammation? Can I ask a quick question about the sarcoid with the two... The sarcoidosis? So, I had a case, I saw a case that looked kind of horizontal, but it was sarcoid. And so, what other ways can you tell? Sometimes it can be difficult, but usually you're going to see involvement around nerves damaged nerves. You're about to get sarcoidal granulomatous inflammation. They always have very high risk inflammatory reactions. They just wipe out the nerves. So, that's helpful. Wasn't",
"med_umls_ids": "[[{'entity': 'Tuberculoid', 'concept_id': 'C0544783', 'confidence': 0.8459237217903137}, {'entity': 'leprosy', 'concept_id': 'C0023343', 'confidence': 1.0}, {'entity': 'sarcoid', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'granulomatous inflammation', 'concept_id': 'C0553697', 'confidence': 1.0}], [{'entity': 'Involvement', 'concept_id': 'C1314939', 'confidence': 1.0}, {'entity': 'damaged nerves', 'concept_id': 'C3887709', 'confidence': 0.8087002038955688}, {'entity': 'sarcoid', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'granulomatous inflammation', 'concept_id': 'C0553697', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_291",
"caption_rating": "7"
},
{
"": "1007025",
"caption": "Presence of nuclear and cytoplasmic inclusion indicating CMV infection which affects mesenchymal derived cells first, endothelial cells and fibroblasts leading to vasculitis and ischemia.",
"image_path": "r7OA0Trj5hQ_image_f812ec50-bd85-4cd2-9331-14ea1298939e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['endothelial cells', 'vasculitis and ischemia', 'endothelial cells', 'vasculitis and ischemia', 'endothelial cells', 'vasculitis and ischemia']",
"noisy_text": " nuclear and cytoplasmic inclusion. These are CMV infection. These are all involving blood vessels. One thing for CMV, it affects mesenchymal derived cells first, endothelial cells and the fibroblasts. Since it's involving the endothelial cells, it produces vasculitis and ischemia. And that's why most of the CMV gastroenteropathy is associated with ischemic changes because of the overlapping vasculitis. Here, it is involving more epithelium. Whereas here, it's involving more endothelium. This is a special strain, gastric biopsy again. You see",
"corrected_text": " nuclear and cytoplasmic inclusion. These are CMV infection. These are all involving blood vessels. One thing for CMV, it affects mesenchymal derived cells first, endothelial cells and the fibroblasts. Since it's involving the endothelial cells, it produces vasculitis and ischemia. And that's why most of the CMV gastroenteropathy is associated with ischemic changes because of the overlapping vasculitis. Here, it is involving more epithelium. Whereas here, it's involving more endothelium. This is a special strain, gastric biopsy again. You see",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'nuclear', 'concept_id': 'C0521447', 'confidence': 1.0}, {'entity': 'cytoplasmic', 'concept_id': 'C0010834', 'confidence': 1.0}, {'entity': 'inclusion', 'concept_id': 'C0007637', 'confidence': 1.0}, {'entity': 'CMV infection', 'concept_id': 'C0010823', 'confidence': 1.0}, {'entity': 'mesenchymal', 'concept_id': 'C1513143', 'confidence': 1.0}, {'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'endothelial cells', 'concept_id': 'C0225336', 'confidence': 1.0}, {'entity': 'fibroblasts', 'concept_id': 'C0016030', 'confidence': 1.0}, {'entity': 'vasculitis', 'concept_id': 'C0042384', 'confidence': 1.0}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_292",
"caption_rating": "9"
},
{
"": "1006386",
"caption": "This was an example of a biopsy from a patient with clinically documented pityriasis lichenoides chronica.",
"image_path": "8S4LeiO6Bbk_image_c8f1c057-4f32-4953-9485-51e33ded345a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Infiltrate within the dermis composed entirely of lymphocytes.', 'Few extravasated erythrocytes in some areas.', 'Fragmented biopsy specimen with bluish stain.', 'Infiltrate within the dermis composed entirely of lymphocytes.', 'Few extravasated erythrocytes in some areas.', 'Fragmented biopsy specimen with bluish stain.', 'Infiltrate within the dermis composed entirely of lymphocytes.', 'Few extravasated erythrocytes in some areas.', 'Fragmented biopsy specimen with bluish stain.', 'Infiltrate within the dermis composed entirely of lymphocytes.', 'Few extravasated erythrocytes in some areas.', 'Fragmented biopsy specimen with bluish stain.']",
"noisy_text": " and if we look at the infiltrate within the dermis, we can see that it's composed entirely of lymphocytes. In some areas, there were a few extravasated erythrocytes, a few of which were carried up into the overlying epidermis. This constellation of findings is most suggestive of pittoriasis liganoides. Clinically, this patient had PLC, or pittoriasis liganoides chronica. I tend to view pittoriasis liganoides as running along a spectrum. A lot of times, we'll refer to the entire spectrum as Leuka Habermann disease, with pittoriasis liganoides chronica being on the one end of the spectrum, and pleva being on the other end of the spectrum, PLC being characterized by more scaly macules or scaly papules, and pleva being characterized by more crusted and eroded papulonecrotic type lesions. But the histology of the two conditions is actually quite similar. It's a matter of degree. With pleva, you're more likely the acute form of the condition to see more spongiosis, ballooning, necrosis, a denser infiltrate, more necrotics along the DEJ, pericaratosis containing neutrophils. With PLC, similar findings, just a little more blunt. The inflammatory infiltrate may be present around the superficial plexus only. One usually can see some pericaratosis, but there aren't as many necrotic keratinocytes along the DEJ, and a lot of times, the alterations within the epidermis are more subtle. But this was an example of biopsy from a patient with clinically documented pittoriasis like in wades clonica. Moving on to slide number 10. This was, I thought, a really cool case. This was a fragmented biopsy specimen, and you can see that the stain is quite bluish. I can't",
"corrected_text": " and if we look at the infiltrate within the dermis, we can see that it's composed entirely of lymphocytes. In some areas, there were a few extravasated erythrocytes, a few of which were carried up into the overlying epidermis. This constellation of findings is most suggestive of pityriasis lichenoides. Clinically, this patient had PLC, or pityriasis lichenoides chronica. I tend to view pityriasis lichenoides as running along a spectrum. A lot of times, we'refer to the entire spectrum as Leuka Habermann disease, with pityriasis lichenoides chronica being on the one end of the spectrum, and pleva being on the other end of the spectrum, PLC being characterized by more scaly macules or scaly papules, and pleva being characterized by more crusted and eroded papulonecrotic type lesions. But the histology of the two conditions is actually quite similar. It's a matter of degree. With pleva, you're more likely the acute form of the condition to see more spongiosis, ballooning, necrosis, a denser infiltrate, more necrotic along the DEJ, parakeratosis containing neutrophils. With PLC, similar findings, just a little more blunt. The inflammatory infiltrate may be present around the superficial plexus only. One usually can see some parakeratosis, but there aren't as many necrotic keratinocytes along the DEJ, and a lot of times, the alterations within the epidermis are more subtle. But this was an example of biopsy from a patient with clinically documented pittoriasis like in chronica. Moving on to slide number 10. This was, I thought, a really cool case. This was a fragmented biopsy specimen, and you can see that the stain is quite bluish. I can't",
"med_umls_ids": "[[{'entity': 'dermal infiltrate', 'concept_id': 'C0332448', 'confidence': 0.8524853587150574}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'extravasated', 'concept_id': 'C0015376', 'confidence': 0.868863582611084}, {'entity': 'erythrocytes', 'concept_id': 'C0014772', 'confidence': 1.0}, {'entity': 'areas', 'concept_id': 'C0205146', 'confidence': 1.0}, {'entity': 'pityriasis', 'concept_id': 'C0032024', 'confidence': 0.9999998807907104}, {'entity': 'lichenoides', 'concept_id': 'C0443248', 'confidence': 0.8475416302680969}], [{'entity': 'Pityriasis lichenoides', 'concept_id': 'C0162853', 'confidence': 1.0}, {'entity': 'running', 'concept_id': 'C0035953', 'confidence': 1.0}, {'entity': 'spectrum', 'concept_id': 'C1883073', 'confidence': 1.0}, {'entity': 'pityriasis lichenoides chronica', 'concept_id': 'C0162851', 'confidence': 1.0}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'scaly macules', 'concept_id': 'C0332573', 'confidence': 0.7616965174674988}, {'entity': 'papules', 'concept_id': 'C0332563', 'confidence': 0.9999999403953552}], [{'entity': 'histology', 'concept_id': 'C0019638', 'confidence': 1.0}, {'entity': 'pityriasis lichenoides', 'concept_id': 'C0162853', 'confidence': 1.0}, {'entity': 'pleva', 'concept_id': 'C0162852', 'confidence': 1.0}, {'entity': 'pleva', 'concept_id': 'C0162852', 'confidence': 1.0}, {'entity': 'acute', 'concept_id': 'C0205178', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'spongiosis', 'concept_id': 'C0702120', 'confidence': 1.0}, {'entity': 'ballooning', 'concept_id': 'C0004704', 'confidence': 1.0}, {'entity': 'necrosis', 'concept_id': 'C0027540', 'confidence': 1.0}], [{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'clinically documented', 'concept_id': 'C1828480', 'confidence': 0.814785361289978}, {'entity': 'pityriasis lichenoides chronica', 'concept_id': 'C0162851', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_293",
"caption_rating": "8"
},
{
"": "1008378",
"caption": "The patient was treated for sarcoidosis and subsequent biopsies showed no more granulomas.",
"image_path": "sDFjOtMAYrk_image_40f283f5-b3a7-423a-9bde-a1595d53e7ad.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['uveitis with characteristic features', 'granulomas in sarcoidosis and Crohn\u2019s disease', 'uveitis with characteristic features', 'granulomas in sarcoidosis and Crohn\u2019s disease']",
"noisy_text": " patient had sarcoid. So I said, this is probably not IBD, clinicians came down, we want to look at the biopsy, of course. It turns out that they went back and talked to the patient. The patient has a history of uveitis with characteristic features that were good for sarcoidosis. Nobody knew about they treated the patient for sarcoid, re-biopsied the patient. And he was fine. There were no more granulomas on multiple repeat biopsies. And now compare those grannies with the grannies in Crohn's. So here's a giant cell right there, but there was a better one right there. So they're like kind of",
"corrected_text": " patient had sarcoid. So I said, this is probably not IBD, clinicians came down, we want to look at the biopsy, of course. It turns out that they went back and talked to the patient. The patient has a history of uveitis with characteristic features that were good for sarcoidosis. Nobody knew about they treated the patient for sarcoid, re-biopsied the patient. And he was fine. There were no more granulomas on multiple repeat biopsies. And now compare those grannies with the grannies in Crohn's. So here's a giant cell right there, but there was a better one right there. So they're like kind of",
"med_umls_ids": "[[{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'suspected', 'concept_id': 'C0332147', 'confidence': 1.0}, {'entity': 'IBD', 'concept_id': 'C0021390', 'confidence': 1.0}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'history', 'concept_id': 'C0019664', 'confidence': 1.0}, {'entity': 'uveitis', 'concept_id': 'C0042164', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'treated', 'concept_id': 'C1522326', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'biopsies', 'concept_id': 'C0005558', 'confidence': 1.0}, {'entity': 'granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}], [{'entity': 'Comparison', 'concept_id': 'C1707455', 'confidence': 1.0}, {'entity': 'granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'Crohn\u2019s disease', 'concept_id': 'C0010346', 'confidence': 0.8916962146759033}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_294",
"caption_rating": "8"
},
{
"": "1008332",
"caption": "The lesion shows a collection of dilated vascular spaces lined by plump endothelial cells with papillary projections, indicating a vascular neoplasm with a biphasic pattern.",
"image_path": "8S4LeiO6Bbk_image_44ce97d9-5997-4adb-a80a-2e2ee7c81a7c.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['dilated vascular spaces', 'plump endothelial cells', 'papillary projections', 'extravasated erythrocytes', 'dilated vascular spaces', 'plump endothelial cells', 'papillary projections', 'extravasated erythrocytes']",
"noisy_text": " we can see that in the central portion of the lesion, we've got a collection of vascular spaces that are quite large or dilated. Many of these are lined by very plump kind of epithelioid or hobnailed endothelial cells, and some of them contain papillary projections that extend into the limina. If you look around, you can see these papillary projections. There are a few extravasated erythrocytes present within the stroma. So clearly, we've got this vascular neoplasma here with these dilated endothelial line spaces, but it's got kind of a bifasic pattern. Centrally, we've got these dilated vessels, but peripheral and beneath that zone, the vessels are somewhat more compressed. They're still lined by some of the plump endothelial cells. And in these various",
"corrected_text": " we can see that in the central portion of the lesion, we've got a collection of vascular spaces that are quite large or dilated. Many of these are lined by very plump kind of epithelioid or hobnailed endothelial cells, and some of them contain papillary projections that extend into the limina. If you look around, you can see these papillary projections. There are a few extravasated erythrocytes present within the stroma. So clearly, we've got this vascular neoplasm here with these dilated endothelial line spaces, but it's got kind of a biphasic pattern. Centrally, we've got these dilated vessels, but peripheral and beneath that zone, the vessels are somewhat more compressed. They're still lined by some of the plump endothelial cells. And in these various",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'collection', 'concept_id': 'C0600644', 'confidence': 1.0}, {'entity': 'dilated', 'concept_id': 'C0700124', 'confidence': 0.9999999403953552}, {'entity': 'vascular spaces', 'concept_id': 'C0225983', 'confidence': 0.819495439529419}, {'entity': 'plump', 'concept_id': 'C1836543', 'confidence': 0.7694027423858643}, {'entity': 'papillary projections', 'concept_id': 'C0016538', 'confidence': 0.7451471090316772}, {'entity': 'vascular neoplasm', 'concept_id': 'C0027668', 'confidence': 1.0}, {'entity': 'biphasic pattern', 'concept_id': 'C1332555', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "758.0",
"width": "1920.0",
"id": "test_295",
"caption_rating": "9"
},
{
"": "1005500",
"caption": "Histopathological description of a specimen with banal appearing melanocytes present within the dermis.",
"image_path": "8S4LeiO6Bbk_image_2a656e84-f2e1-48c2-9cf0-1df8b85c49a1.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['cytoplasm', 'dermis']",
"noisy_text": " appearance, a round oval nuclei and a moderate amount of cytoplasm. And then we have nest cords and strands of otherwise banal appearing or banal appearing melanocytes present within the underlying dermis. There is evidence of maturation with depth in these sections, and no mitotic pairs. In the central portion of the specimen, you can see that the dermis is a little more sclerotic. And we've got the presence of separately heavily pigmented melanovagias. And then if we look at our top piece of tissue, again, we have the more banal appearing melanocytes out of the periphery. And centrally, we've got embedded within a sclerotic stroma a second distinct morphologic population of melanocytes. Some of these are dendritic, others have spindled or fusiform-shaped",
"corrected_text": " appearance, a round oval nuclei and a moderate amount of cytoplasm. And then we have nest cords and strands of otherwise banal appearing or banal appearing melanocytes present within the underlying dermis. There is evidence of maturation with depth in these sections, and no mitotic pairs. In the central portion of the specimen, you can see that the dermis is a little more sclerotic. And we've got the presence of separately heavily pigmented melanovagias. And then if we look at our top piece of tissue, again, we have the more banal appearing melanocytes out of the periphery. And centrally, we've got embedded within a sclerotic stroma a second distinct morphologic population of melanocytes. Some of these are dendritic, others have spindle-shaped or fusiform-shaped",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'specimen', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'banal', 'concept_id': 'C0004722', 'confidence': 0.7279530763626099}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}], [{'entity': 'Evidence', 'concept_id': 'C3887511', 'confidence': 1.0}, {'entity': 'maturation', 'concept_id': 'C0678723', 'confidence': 1.0}, {'entity': 'depth', 'concept_id': 'C0205125', 'confidence': 1.0}, {'entity': 'mitotic', 'concept_id': 'C1513354', 'confidence': 1.0}, {'entity': 'pairs', 'concept_id': 'C0600436', 'confidence': 0.8094210028648376}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'heavily', 'concept_id': 'C0337678', 'confidence': 0.6902515292167664}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'melanophages', 'concept_id': 'C3280463', 'confidence': 0.9375340938568115}], [{'entity': 'Sclerotic', 'concept_id': 'C0036429', 'confidence': 0.9999999403953552}, {'entity': 'stroma', 'concept_id': 'C0927195', 'confidence': 1.0}, {'entity': 'morphologic population', 'concept_id': 'C0543482', 'confidence': 0.699425995349884}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_296",
"caption_rating": "8"
},
{
"": "1005820",
"caption": "The lesion tends to occur along the ulnar aspect of the fifth digit and can be bilateral.",
"image_path": "8S4LeiO6Bbk_image_05eec250-fd22-4ed8-93df-a011dc2c30f2.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['nerve fascicles', 'spindle-shaped cells', 'rudimentary supernumerary digit', 'ulnar aspect of the fifth digit', 'acquired digital fibroma', 'acquired digital fibrokeratoma', 'trichilemmal cyst', 'nerve fascicles', 'spindle-shaped cells', 'rudimentary supernumerary digit', 'ulnar aspect of the fifth digit', 'acquired digital fibroma', 'acquired digital fibrokeratoma', 'trichilemmal cyst', 'nerve fascicles', 'spindle-shaped cells', 'rudimentary supernumerary digit', 'ulnar aspect of the fifth digit', 'acquired digital fibroma', 'acquired digital fibrokeratoma', 'trichilemmal cyst']",
"noisy_text": " core here we've got several well-defined nerve fascicles and the spindled cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions of course tend to occur along the ulnar eye aspect of the fifth digit. They're not infrequently bilateral and the key differential here of course is an acquired digital fibroma or an acquired digital fibrocarotoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if",
"corrected_text": " core here we've got several well-defined nerve fascicles and the spindle cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions of course tend to occur along the ulnar eye aspect of the fifth digit. They're not infrequently bilateral and the key differential here of course is an acquired digital fibroma or an acquired digital fibrokeratoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if",
"med_umls_ids": "[[{'entity': 'Well-defined nerve fascicles', 'concept_id': 'C1185741', 'confidence': 0.5682494640350342}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'S100', 'concept_id': 'C3273837', 'confidence': 1.0}, {'entity': 'SOX10', 'concept_id': 'C1420317', 'confidence': 0.9999998807907104}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'rudimentary supernumerary digit', 'concept_id': 'C0152427', 'confidence': 0.8142021894454956}], [{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'ulnar', 'concept_id': 'C0442044', 'confidence': 1.0}, {'entity': 'aspect', 'concept_id': 'C1547011', 'confidence': 1.0}, {'entity': 'fifth digit', 'concept_id': 'C0230403', 'confidence': 0.912693440914154}, {'entity': 'bilateral', 'concept_id': 'C0238767', 'confidence': 1.0}], [{'entity': 'differential diagnosis', 'concept_id': 'C0011906', 'confidence': 1.0}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}, {'entity': 'digital fibroma', 'concept_id': 'C4538745', 'confidence': 0.8997364640235901}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}], [{'entity': 'Trichilemmal cyst', 'concept_id': 'C2266788', 'confidence': 1.0}, {'entity': 'biopsy specimen', 'concept_id': 'C0677862', 'confidence': 1.0}, {'entity': 'slide number', 'concept_id': 'C3828004', 'confidence': 0.8261933326721191}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_297",
"caption_rating": "8"
},
{
"": "1006905",
"caption": "Collections of immune cells are present throughout the dermis, surrounded by a narrow cuff of mononuclear cells.",
"image_path": "hoV-JkD6Wb0_image_76a7e23e-ea5d-4876-81e3-95755ad3101d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['ectatic vessels', 'papillary dermis', 'perivascular infiltrate of lymphocytes', 'collections of immune cells', 'narrow cuff of mononuclear cells', 'ectatic vessels', 'papillary dermis', 'perivascular infiltrate of lymphocytes', 'collections of immune cells', 'narrow cuff of mononuclear cells']",
"noisy_text": " and we'll take a look at two of them, you had to review similar findings, bisected punch. And as expected, there are ectatic vessels here. Let me tilt the slide here. And the papillary dermis, a little bit of pallor consistent with edema, a little bit of a perivascular infiltrate of lymphocytes. And then present throughout the dermis, there are a few collections of epithelioid histiocytes. Here, there's one right there. And down here, we have another collection of epithelioid histiocytes. These are surrounded by a narrow cuff of mononuclear cells, but many",
"corrected_text": " and we'll take a look at two of them, you had to review similar findings, bisected punch. And as expected, there are ectatic vessels here. Let me tilt the slide here. And the papillary dermis, a little bit of pallor consistent with edema, a little bit of a perivascular infiltrate of lymphocytes. And then present throughout the dermis, there are a few collections of epithelioid histiocytes. Here, there's one right there. And down here, we have another collection of epithelioid histiocytes. These are surrounded by a narrow cuff of mononuclear cells, but many",
"med_umls_ids": "[[{'entity': 'Ectatic vessels', 'concept_id': 'C0005847', 'confidence': 0.7720959186553955}, {'entity': 'papillary dermis', 'concept_id': 'C0682598', 'confidence': 1.0}, {'entity': 'pallor', 'concept_id': 'C0030232', 'confidence': 1.0}, {'entity': 'consistent with', 'concept_id': 'C0332290', 'confidence': 1.0}, {'entity': 'edema', 'concept_id': 'C0013604', 'confidence': 0.9999999403953552}, {'entity': 'perivascular', 'concept_id': 'C0442165', 'confidence': 1.0}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}], [{'entity': 'Collections', 'concept_id': 'C0600644', 'confidence': 0.8663196563720703}, {'entity': 'immune cells', 'concept_id': 'C4330475', 'confidence': 0.8268961906433105}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'surrounded', 'concept_id': 'C1282914', 'confidence': 1.0}, {'entity': 'cuff', 'concept_id': 'C0441107', 'confidence': 1.0}, {'entity': 'mononuclear cells', 'concept_id': 'C0806987', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_298",
"caption_rating": "8"
},
{
"": "1005153",
"caption": "Peritoneal epithelial hyperpressure can compress the glomerulus, leading to the formation of a crescent.",
"image_path": "WhnEXkBN4D8_image_af6baf36-21c1-4ead-89f1-558f577cb4e4.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Renal', 'Hematopathology', 'Soft tissue']",
"roi_text": "['Peritoneal epithelial hyperpressure compressing the glomerulus', 'Compressed glomerulus forming a crescent']",
"noisy_text": " If you see this, these are nothing but your peritoneal epithelial hyperpressure coming and compressing the glomeruli. That's one, right? Now with this information, let's go and look at this glomeruli again. Look at this glomeruli. This is the capsule. Everything else is compressed. So can I call this a beautiful crescent? Yes. So as a pathologist, when you compare the crescent, you have to say whether it's a fibrous crescent or a fibrous cellular crescent because that also makes sense here. Here, I",
"corrected_text": " If you see this, these are nothing but your peritoneal epithelial hyperpressure coming and compressing the glomeruli. That's one, right? Now with this information, let's go and look at this glomeruli again. Look at this glomeruli. This is the capsule. Everything else is compressed. So can I call this a beautiful crescent? Yes. So as a pathologist, when you compare the crescent, you have to say whether it's a fibrous crescent or a fibrous cellular crescent because that also makes sense here. Here, I",
"med_umls_ids": "[[{'entity': 'Peritoneal', 'concept_id': 'C0031153', 'confidence': 1.0}, {'entity': 'epithelial hyperpressure', 'concept_id': 'C0014599', 'confidence': 0.6601702570915222}, {'entity': 'compress', 'concept_id': 'C0180053', 'confidence': 1.0}, {'entity': 'glomerulus', 'concept_id': 'C0022663', 'confidence': 1.0}, {'entity': 'formation', 'concept_id': 'C0220781', 'confidence': 1.0}, {'entity': 'crescent', 'concept_id': 'C0444628', 'confidence': 1.0}], [{'entity': 'Pathologists', 'concept_id': 'C0334866', 'confidence': 1.0}, {'entity': 'differentiate', 'concept_id': 'C0205615', 'confidence': 0.9999998807907104}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}, {'entity': 'crescents', 'concept_id': 'C0444628', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_299",
"caption_rating": "8"
},
{
"": "1005622",
"caption": "Presence of luminal ruffling in prostate glands is a reassuring sign as prostate cancer usually has sharp luminal borders.",
"image_path": "iklRyY1nBIE_image_3a278ee7-85de-4e68-9956-e24372331084.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['luminal ruffling', 'prostate glands', 'early corpora and mucin formation', 'atrophic gland', 'luminal ruffling', 'prostate glands', 'early corpora and mucin formation', 'atrophic gland']",
"noisy_text": " And if you go a bit closer, you can see that they have a little bit of luminal ruffling. When you see luminal ruffling, that should make you feel a little bit more comfortable, because prostate cancer usually has sharp luminal borders. The problem is the previous case I showed you actually had sharp luminal borders, even though it was partial atrophy. So that's what makes this tricky. But in this case, you can see the fairly well circumscribed, one of the glands even has a little bit of early corpora and malatial formation. But you also have this gland over here that looks somewhat similar, but a little bit more atrophic. And if you look at the corresponding immunosuchemical stain and that focus of interest, we'll see what happens. So again, this",
"corrected_text": " And if you go a bit closer, you can see that they have a little bit of luminal ruffling. When you see luminal ruffling, that should make you feel a little bit more comfortable, because prostate cancer usually has sharp luminal borders. The problem is the previous case I showed you actually had sharp luminal borders, even though it was partial atrophy. So that's what makes this tricky. But in this case, you can see the fairly well circumscribed, one of the glands even has a little bit of early corpora and mucin formation. But you also have this gland over here that looks somewhat similar, but a little bit more atrophic. And if you look at the corresponding immunohistochemical stain and that focus of interest, we'll see what happens. So again, this",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'luminal ruffling', 'concept_id': 'C3269125', 'confidence': 0.690064549446106}, {'entity': 'prostate glands', 'concept_id': 'C0033572', 'confidence': 0.8152219653129578}, {'entity': 'prostate cancer', 'concept_id': 'C0376358', 'confidence': 1.0}, {'entity': 'luminal borders', 'concept_id': 'C0524462', 'confidence': 0.6706532835960388}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_300",
"caption_rating": "9"
},
{
"": "1009076",
"caption": "Reactive cytologic atypia can be seen in cases of treatment effect, such as chemotherapy or radiation.",
"image_path": "sDFjOtMAYrk_image_7d5336a2-b407-43a5-865b-ee33a577ea03.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['prominent nucleoli', 'reactive cytologic atypia', 'chemotherapy or radiation', 'cancer', 'inflammatory bowel disease']",
"noisy_text": " I'm missing it. Okay. I think what's catching my eye for the most part is the prominent nucleolide, but what would you say about the NC ratio? Yeah, I think overall it's low. You have lots, loads of cytoplasm. Even though the nuclei are big, you have loads of cytoplasm. So, with this morphology, first of all, the question was, you know, inflammatory bowel disease. Okay, maybe, but the cytology is not great for the degree of reactive epithelial changes. Although you can have some crazy looking inflammatory bowel disease cases, it's really crazy. When I see crazy bizarre epithelial atypia, I think about treatment effect, either chemotherapy or radiation. Both of them can give you this crazy cytologic atypia that sometimes may actually make you think of cancer. We've got a couple of cases received in consultation. I'm remembering one specifically in the stomach where the question is, what about this cancer? And it wasn't. It was just crazy reactive epithelial changes in a patient who we didn't know, but the patient had received radiotherapy for lung cancer. And it definitely looked a lot like malignancy, but there was something not right about it. So, this patient was receiving at the same time chemotherapy for his pancreatic cancer. One thing you can see in patients, especially when they're receiving radiation,",
"corrected_text": " I'm missing it. Okay. I think what's catching my eye for the most part is the prominent nucleoli, but what would you say about the NC ratio? Yeah, I think overall it's low. You have lots, loads of cytoplasm. Even though the nuclei are big, you have loads of cytoplasm. So, with this morphology, first of all, the question was, you know, inflammatory bowel disease. Okay, maybe, but the cytology is not great for the degree of reactive epithelial changes. Although you can have some crazy looking inflammatory bowel disease cases, it's really crazy. When I see crazy bizarre epithelial atypia, I think about treatment effect, either chemotherapy or radiation. Both of them can give you this reactive cytologic atypia that sometimes may actually make you think of cancer. We've got a couple of cases received in consultation. I'm remembering one specifically in the stomach where the question is, what about this cancer? And it wasn't. It was just crazy reactive epithelial changes in a patient who we didn't know, but the patient had received radiotherapy for lung cancer. And it definitely looked a lot like malignancy, but there was something not right about it. So, this patient was receiving at the same time chemotherapy for his pancreatic cancer. One thing you can see in patients, especially when they're receiving radiation,",
"med_umls_ids": "[[{'entity': 'Prominent', 'concept_id': 'C0205402', 'confidence': 0.9999999403953552}, {'entity': 'nucleoli', 'concept_id': 'C0007609', 'confidence': 0.8710004091262817}, {'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'NC', 'concept_id': 'C0027964', 'confidence': 1.0}, {'entity': 'ratio', 'concept_id': 'C0456603', 'confidence': 1.0}, {'entity': 'low', 'concept_id': 'C0205251', 'confidence': 0.9999999403953552}], [{'entity': 'Reactive cytologic atypia', 'concept_id': 'C0333865', 'confidence': 0.8587049245834351}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'treatment effect', 'concept_id': 'C1518681', 'confidence': 1.0}, {'entity': 'chemotherapy', 'concept_id': 'C0013216', 'confidence': 1.0}, {'entity': 'radiation', 'concept_id': 'C0034519', 'confidence': 1.0}], [{'entity': 'Crazy', 'concept_id': 'C0424157', 'confidence': 0.6988691687583923}, {'entity': 'cancer', 'concept_id': 'C0006826', 'confidence': 0.9999998807907104}], [{'entity': 'Inflammatory bowel disease', 'concept_id': 'C0021390', 'confidence': 1.0}, {'entity': 'cytology', 'concept_id': 'C0010818', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_301",
"caption_rating": "9"
},
{
"": "1008827",
"caption": "The glands in some areas appear atrophic and have prominent cell nuclei, while in other areas they appear bland and have less prominent nuclei.",
"image_path": "iklRyY1nBIE_image_adc28341-9f87-429b-98cd-8930d149ff80.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['Prominent cell nuclei in some glands', 'Atrophy in some areas', 'Possibility of prior therapy']",
"noisy_text": " If we go a bit closer, the nuclei are not that prominent. You see some prominent nuclei in some of the glands. But some other glands just look very bland. And it's almost like the case is sending mixed messages. In some areas, you see prominent nuclei. In some other areas, you don't see prominent nuclei. It looks very atrophic. And this obviously makes people very nervous when you see a lot of atrophy. The other issue is you could wonder, or you could ask, did this patient get any prior therapy? That's something",
"corrected_text": " If we go a bit closer, the nuclei are not that prominent. You see some prominent cell nuclei in some of the glands. But some other glands just look very bland. And it's almost like the case is sending mixed messages. In some areas, you see prominent cell nuclei. In some other areas, you don't see prominent cell nuclei. It looks very atrophic. And this obviously makes people very nervous when you see a lot of atrophy. The other issue is you could wonder, or you could ask, did this patient get any prior therapy? That's something",
"med_umls_ids": "[[{'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'areas', 'concept_id': 'C0205146', 'confidence': 1.0}, {'entity': 'atrophic', 'concept_id': 'C0151514', 'confidence': 1.0}, {'entity': 'cell nuclei', 'concept_id': 'C0007610', 'confidence': 1.0}, {'entity': 'bland', 'concept_id': 'C0227475', 'confidence': 0.7435316443443298}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}], [{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'atrophy', 'concept_id': 'C0333641', 'confidence': 1.0}, {'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}], [{'entity': 'therapy', 'concept_id': 'C0039798', 'confidence': 0.9999999403953552}, {'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'raised', 'concept_id': 'C0442818', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_302",
"caption_rating": "8"
},
{
"": "1005828",
"caption": "Pigmented histiocytes containing hemocyanin are present in the lesion.",
"image_path": "8S4LeiO6Bbk_image_c5f14cb3-8d7b-4a19-89cc-edafae5bc6ad.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['lipid vacuoles', 'multinucleated histiocytes', 'ringed siderophages', 'pigmented histiocytes', 'hemocyanin']",
"noisy_text": " large histiocytes containing lipid. Some of them are multi-nucleated and some of these are actually ringed siderophages. So we see large multi-nucleated histiocytes with a ring of nuclei and they contain not only lipid vacuoles but hemocentaurant. And these are particularly common in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes as suspected is hemocentaurant. If you notice, it's got kind of that golden brown color. If you had a sub-stage condenser or a fine focus knob, you would see that it's somewhat refractile, but unfortunately, we can't use that particular tool when we're looking at scanned images.",
"corrected_text": " large histiocytes containing lipid. Some of them are multinucleated and some of these are actually ringed siderophages. So we see large multinucleated histiocytes with a ring of nuclei and they contain not only lipid vacuoles but hemosiderin. And these are particularly common in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes as suspected is hemosiderin. If you notice, it's got kind of that golden brown color. If you had a sub-stage condenser or a fine focus knob, you would see that it's somewhat refractile, but unfortunately, we can't use that particular tool when we're looking at scanned images.",
"med_umls_ids": "[[{'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'lipid', 'concept_id': 'C0023779', 'confidence': 1.0}, {'entity': 'multinucleated', 'concept_id': 'C0333740', 'confidence': 1.0}, {'entity': 'ringed', 'concept_id': 'C0325501', 'confidence': 0.77345871925354}, {'entity': 'siderophages', 'concept_id': 'C1136253', 'confidence': 0.7251443266868591}], [{'entity': 'Hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}], [{'entity': 'Pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_303",
"caption_rating": "8"
},
{
"": "1004506",
"caption": "The lesion is asymmetrical, poorly circumscribed, and goes deep.",
"image_path": "LlPaENuqzVQ_image_8881ae2e-2460-4641-8ebe-08c0de40ed9e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['Asymmetrical lesion', 'Poorly circumscribed lesion', 'Lesion that goes deep', 'Lesion that goes deep']",
"noisy_text": " You can really get it down pretty well if you just apply the criteria. So you like benign or malignant here? It's not very well circumscribed, and it looks like there's some erosion on top. That may be from a prior biopsy, interestingly enough. But yeah, look at its symmetry. Is this symmetrical? Not really. No, no, no. It's pretty big. This is probably about a centimeter excision. This lesion is pretty big. It goes deep. It's asymmetrical, poorly circumscribed. Totally like epithelial. So 80% of the work is done. So now all we have to do is just go to higher magnification and decide what kind of specific differentiation we're looking at,",
"corrected_text": " You can really get it down pretty well if you just apply the criteria. So you like benign or malignant here? It's not very well circumscribed, and it looks like there's some erosion on top. That may be from a prior biopsy, interestingly enough. But yeah, look at its symmetry. Is this symmetrical? Not really. No, no, no. It's pretty big. This is probably about a centimeter excision. This lesion is pretty big. It goes deep. It's asymmetrical, poorly circumscribed. Totally like epithelial. So 80% of the work is done. So now all we have to do is just go to higher magnification and decide what kind of specific differentiation we're looking at,",
"med_umls_ids": "[[{'entity': 'narrator', 'concept_id': 'C1135957', 'confidence': 0.7711340188980103}, {'entity': 'criteria', 'concept_id': 'C0243161', 'confidence': 0.9999998807907104}, {'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'benign', 'concept_id': 'C0205183', 'confidence': 1.0}, {'entity': 'malignant', 'concept_id': 'C0205282', 'confidence': 1.0}], [{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'asymmetrical', 'concept_id': 'C0332514', 'confidence': 1.0}, {'entity': 'poorly circumscribed', 'concept_id': 'C1282914', 'confidence': 0.8116709589958191}, {'entity': 'deep', 'concept_id': 'C0205125', 'confidence': 0.9999999403953552}], [{'entity': 'narrator', 'concept_id': 'C1135957', 'confidence': 0.7711340188980103}, {'entity': 'notes', 'concept_id': 'C1317574', 'confidence': 1.0}, {'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'epithelial', 'concept_id': 'C0221908', 'confidence': 1.0}, {'entity': 'nature', 'concept_id': 'C0349590', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_304",
"caption_rating": "8"
},
{
"": "1004508",
"caption": "Granulomas can be caused by tuberculosis, sarcoidosis, fungal infections, idiopathic or foreign bodies.",
"image_path": "r7OA0Trj5hQ_image_1d23a123-faf8-4547-ba27-188309145df0.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Granulomas in the lamina propria', 'Lymphoid follicles in the stomach', 'Cytoplasmic inclusions', 'Granulomas in the lamina propria', 'Lymphoid follicles in the stomach', 'Cytoplasmic inclusions', 'Granulomas in the lamina propria', 'Lymphoid follicles in the stomach', 'Cytoplasmic inclusions']",
"noisy_text": " So this is chronic colitis with activity. These are granulomas in the lamina propria. Think of tuberculosis in India, sarcoidosis, fungal infections, or idiopathic, or foreign bodies. So those are all the four main things. Any granuloma, infectious or non-infectious. When infectious, is it necrotizing or non-necrotizing? Lymphoid follicles, again, abnormal in the stomach. And they are seen in the lamina propria, chronic gastroenteritis. You can all identify these beautiful inclusions. And some cytoplasmic inclusions also, nuclear and",
"corrected_text": " So this is chronic colitis with activity. These are granulomas in the lamina propria. Think of tuberculosis in India, sarcoidosis, fungal infections, or idiopathic, or foreign bodies. So those are all the four main things. Any granuloma, infectious or non-infectious. When infectious, is it necrotizing or non-necrotizing? Lymphoid follicles, again, abnormal in the stomach. And they are seen in the lamina propria, chronic gastroenteritis. You can all identify these beautiful inclusions. And some cytoplasmic inclusions also, nuclear and",
"med_umls_ids": "[[{'entity': 'Chronic colitis', 'concept_id': 'C0267375', 'confidence': 0.9999999403953552}, {'entity': 'activity', 'concept_id': 'C0026606', 'confidence': 1.0}, {'entity': 'granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}], [{'entity': 'Granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}, {'entity': 'tuberculosis', 'concept_id': 'C0041296', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'fungal infections', 'concept_id': 'C0026946', 'confidence': 1.0}, {'entity': 'idiopathic', 'concept_id': 'C0332240', 'confidence': 0.9999998807907104}, {'entity': 'foreign bodies', 'concept_id': 'C0016542', 'confidence': 1.0}], [{'entity': 'Lymphoid follicles', 'concept_id': 'C0229654', 'confidence': 0.9380706548690796}, {'entity': 'abnormal', 'concept_id': 'C0205161', 'confidence': 1.0}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'chronic gastroenteritis', 'concept_id': 'C0017160', 'confidence': 0.8353270292282104}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_305",
"caption_rating": "8"
},
{
"": "1006505",
"caption": "A skin biopsy has been completely excised and the lesion is diagnosed as molluscum contagiosum, which is a contagious virus.",
"image_path": "1DP288T6QqU_image_6f1bab13-6de6-48e6-9619-e8183c2352b6.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Pediatric']",
"roi_text": "['Cut skin biopsy', 'Lesion diagnosed as molluscum contagiosum']",
"noisy_text": " And the other side of this cut skin biopsy looks exactly the same. Also notice that the parts of the normal skin around it look fairly normal. And specifically, this lesion has been completely excised. It's almost a shame to diagnose this lesion in terms of cells and stuff like that. I will. But let me tell you, there is nothing else in the world on the skin that looks like this. And even inexperienced dermatologists and inexperienced pathologists can take a look at this. And bingo, they say instantly, molluscum contagiosum. It's a virus. And it's contagious. And that's why they call it molluscum contagiosum. I'm going to describe it in more particular language anyway. Notice how",
"corrected_text": " And the other side of this cut skin biopsy looks exactly the same. Also notice that the parts of the normal skin around it look fairly normal. And specifically, this lesion has been completely excised. It's almost a shame to diagnose this lesion in terms of cells and stuff like that. I will. But let me tell you, there is nothing else in the world on the skin that looks like this. And even inexperienced dermatologists and inexperienced pathologists can take a look at this. And bingo, they say instantly, molluscum contagiosum. It's a virus. And it's contagious. And that's why they call it molluscum contagiosum. I'm going to describe it in more particular language anyway. Notice how",
"med_umls_ids": "[[{'entity': 'skin biopsy', 'concept_id': 'C0150866', 'confidence': 0.9999999403953552}, {'entity': 'excised', 'concept_id': 'C1444670', 'confidence': 0.7215964794158936}, {'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'diagnosed', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'molluscum contagiosum', 'concept_id': 'C0026393', 'confidence': 1.0}, {'entity': 'contagious virus', 'concept_id': 'C0029200', 'confidence': 0.7398762106895447}]]",
"magnification": "0.0",
"height": "720.0",
"width": "760.0",
"id": "test_306",
"caption_rating": "8"
},
{
"": "1005050",
"caption": "Ganglion cells in the submucosa are a normal component and may be mistaken for malignancy.",
"image_path": "r7OA0Trj5hQ_image_c0bd25a7-9df4-46e4-9c52-8709b5207449.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['submucosa', 'submucosa']",
"noisy_text": " for example, carotid endoartrectomy or abdominal aortic encephalopathy, that history is very important for cholesterol emboli. Here, there is more like a neural hypertrophy. Whenever you see neural hypertrophy, you have to think of Crohn's disease. Here, you see the ganglion cells in the submicosa. When you see ganglion cells, these are normal component of the submicosa. And why I am showing it, sometimes you may think of malignancy. Here, you may not think of it. And another point, these are all the cells we are looking in congenital mecagola. So if you don't see them in the submicosa in frozen section, again, this will qualify for congenital mecagola. Here, another tricky thing. This is",
"corrected_text": " for example, carotid endarterectomy or abdominal aortic encephalopathy, that history is very important for cholesterol emboli. Here, there is more like a neural hypertrophy. Whenever you see neural hypertrophy, you have to think of Crohn's disease. Here, you see the ganglion cells in the submucosa. When you see ganglion cells, these are normal component of the submucosa. And why I am showing it, sometimes you may think of malignancy. Here, you may not think of it. And another point, these are all the cells we are looking in congenital megacolon. So if you don't see them in the submucosa in frozen section, again, this will qualify for congenital megacolon. Here, another tricky thing. This is",
"med_umls_ids": "[[{'entity': 'History', 'concept_id': 'C0019664', 'confidence': 1.0}, {'entity': 'carotid endarterectomy', 'concept_id': 'C0014099', 'confidence': 1.0}, {'entity': 'abdominal aortic encephalopathy', 'concept_id': 'C0507867', 'confidence': 0.6308470964431763}, {'entity': 'cholesterol emboli', 'concept_id': 'C0149649', 'confidence': 0.8653062582015991}], [{'entity': 'Neural hypertrophy', 'concept_id': 'C0020564', 'confidence': 0.8345715999603271}, {'entity': \"Crohn's disease\", 'concept_id': 'C0010346', 'confidence': 1.0}], [{'entity': 'Ganglion cells', 'concept_id': 'C0228071', 'confidence': 1.0}, {'entity': 'submucosa', 'concept_id': 'C0225344', 'confidence': 1.0}, {'entity': 'malignancy', 'concept_id': 'C0006826', 'confidence': 1.0}], [{'entity': 'Ganglion cells', 'concept_id': 'C0228071', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'congenital megacolon', 'concept_id': 'C0019569', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_307",
"caption_rating": "9"
},
{
"": "1004222",
"caption": "Myxoid liposarcoma and lipoblastoma can have a close morphological overlap in children.",
"image_path": "pBR26SS0FX8_image_89e552f2-936d-4b04-95ec-e323ca972716.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Hematopathology', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " molecular confirmation on for sure, to be sure of. And the other thing is that in a kid, if you see something that you think looks like myxoid liposarcoma, the first thing you should think of is lipoblastoma, which can have a very close overlap morphologically and look very similar to this. There are some differences, but it's very similar. And I feel like if I've got any doubt, I wanna do fish to be sure, because the difference is totally benign versus malignant. And a big difference for the kid. And it's real easy to solve with molecular. So I've",
"corrected_text": " molecular confirmation on for sure, to be sure of. And the other thing is that in a kid, if you see something that you think looks like myxoid liposarcoma, the first thing you should think of is lipoblastoma, which can have a very close overlap morphologically and look very similar to this. There are some differences, but it's very similar. And I feel like if I've got any doubt, I wanna do fish to be sure, because the difference is totally benign versus malignant. And a big difference for the kid. And it's real easy to solve with molecular. So I've",
"med_umls_ids": "[[{'entity': 'Myxoid liposarcoma', 'concept_id': 'C0206634', 'confidence': 1.0}, {'entity': 'lipoblastoma', 'concept_id': 'C1260965', 'confidence': 0.9999998807907104}, {'entity': 'morphological', 'concept_id': 'C0543482', 'confidence': 1.0}, {'entity': 'overlap', 'concept_id': 'C0185027', 'confidence': 0.9999999403953552}, {'entity': 'children', 'concept_id': 'C0008059', 'confidence': 0.9999998807907104}], [{'entity': 'Fish', 'concept_id': 'C0016163', 'confidence': 0.9999998807907104}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'benign', 'concept_id': 'C0205183', 'confidence': 1.0}, {'entity': 'malignant tumors', 'concept_id': 'C0006826', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_308",
"caption_rating": "8"
},
{
"": "1008085",
"caption": "Presence of several melanocytes, some forming nests, some as confluence solitary units, along the base of the matrix epithelium in the matrix layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern.",
"image_path": "8S4LeiO6Bbk_image_525701b0-e1bc-4c80-8310-ec56f677f9eb.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Presence of several melanocytes', 'too many melanocytes']",
"noisy_text": " examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matricle epithelium in the matricle layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that being said, we'll go ahead and move on to slide number two, which was a melanin A or Mk1 immunohistochemical stain of this same piece of tissue. Underneath this bubble here we have our control. This is",
"corrected_text": " examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matrix epithelium in the matrix layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that being said, we'll go ahead and move on to slide number two, which was a melanin A or Mk1 immunohistochemical stain of this same piece of tissue. Underneath this bubble here we have our control. This is",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'nests', 'concept_id': 'C0035253', 'confidence': 0.7275967001914978}, {'entity': 'confluence', 'concept_id': 'C0226863', 'confidence': 0.857487678527832}, {'entity': 'solitary units', 'concept_id': 'C0205171', 'confidence': 0.7227572798728943}, {'entity': 'base', 'concept_id': 'C0002055', 'confidence': 1.0}, {'entity': 'matrix epithelium', 'concept_id': 'C0014609', 'confidence': 0.7584323883056641}, {'entity': 'matrix layer', 'concept_id': 'C0331858', 'confidence': 0.71736741065979}, {'entity': 'basal layer', 'concept_id': 'C0221925', 'confidence': 1.0}, {'entity': 'matrix', 'concept_id': 'C0331858', 'confidence': 1.0}, {'entity': 'upper portions', 'concept_id': 'C0449719', 'confidence': 0.6251541972160339}, {'entity': 'matrix', 'concept_id': 'C0331858', 'confidence': 1.0}, {'entity': 'pagetoid', 'concept_id': 'C1518847', 'confidence': 0.8801172375679016}, {'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}], [{'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'matrix', 'concept_id': 'C0331858', 'confidence': 1.0}, {'entity': 'suspicious', 'concept_id': 'C0750493', 'confidence': 1.0}, {'entity': 'melanoma', 'concept_id': 'C0025202', 'confidence': 1.0}, {'entity': 'in situ', 'concept_id': 'C0444498', 'confidence': 0.9999999403953552}]]",
"magnification": "1.0",
"height": "758.0",
"width": "1920.0",
"id": "test_309",
"caption_rating": "9"
},
{
"": "1009511",
"caption": "Presence of spongiosis with exocytosis of lymphocytes into widened intracellular spaces, mounds of parakeratosis within the stratum corneum, scattered dyskeratotic cells within the epidermis, and an infiltrate composed entirely of lymphocytes within the dermis. These findings are most suggestive of pityriasis lichenoides.",
"image_path": "8S4LeiO6Bbk_image_de15cf1a-c5f9-4c9d-ad1b-28353e4df116.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Spongiosis with exocytosis of lymphocytes', 'Mounds of parakeratosis within the stratum corneum', 'Infiltrate composed entirely of lymphocytes within the dermis', 'Extravasated erythrocytes carried up into the overlying epidermis', 'Spongiosis with exocytosis of lymphocytes', 'Mounds of parakeratosis within the stratum corneum', 'Infiltrate composed entirely of lymphocytes within the dermis', 'Extravasated erythrocytes carried up into the overlying epidermis']",
"noisy_text": " infiltrate. In this particular instance, there's also a little bit of spongiosis with exocytosis of lymphocytes into widened intracellular spaces, and there are some mounds of perikaratosis within the stratum corneum. Within the epidermis, there were a few scattered dyskeratotic cells not present in great number, and if we look at the infiltrate within the dermis, we can see that it's composed entirely of lymphocytes. In some areas, there were a few extravasated erythrocytes, a few of which were carried up into the overlying epidermis. This constellation of findings is most suggestive of pittoriasis liganoides. Clinically, this patient had PLC, or pittoriasis liganoides chronica. I",
"corrected_text": " infiltrate. In this particular instance, there's also a little bit of spongiosis with exocytosis of lymphocytes into widened intracellular spaces, and there are some mounds of parakeratosis within the stratum corneum. Within the epidermis, there were a few scattered dyskeratotic cells not present in great number, and if we look at the infiltrate within the dermis, we can see that it's composed entirely of lymphocytes. In some areas, there were a few extravasated erythrocytes, a few of which were carried up into the overlying epidermis. This constellation of findings is most suggestive of pityriasis lichenoides. Clinically, this patient had PLC, or pityriasis lichenoides chronica. I",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'spongiosis', 'concept_id': 'C0702120', 'confidence': 1.0}, {'entity': 'exocytosis', 'concept_id': 'C0015283', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'intracellular', 'concept_id': 'C0175996', 'confidence': 1.0}, {'entity': 'spaces', 'concept_id': 'C1883067', 'confidence': 0.7782474160194397}, {'entity': 'mounds', 'concept_id': 'C2717795', 'confidence': 0.736616313457489}, {'entity': 'parakeratosis', 'concept_id': 'C0030436', 'confidence': 1.0}, {'entity': 'stratum corneum', 'concept_id': 'C0221921', 'confidence': 1.0}, {'entity': 'scattered', 'concept_id': 'C0439742', 'confidence': 1.0}, {'entity': 'dyskeratotic cells', 'concept_id': 'C1512098', 'confidence': 0.8970272541046143}, {'entity': 'epidermis', 'concept_id': 'C0014520', 'confidence': 1.0}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'findings', 'concept_id': 'C2607943', 'confidence': 1.0}, {'entity': 'pityriasis', 'concept_id': 'C0032024', 'confidence': 0.9999998807907104}, {'entity': 'lichenoides', 'concept_id': 'C0443248', 'confidence': 0.8475416302680969}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_310",
"caption_rating": "9"
},
{
"": "1005501",
"caption": "Evidence of maturation with depth and no mitotic pairs.",
"image_path": "8S4LeiO6Bbk_image_2a656e84-f2e1-48c2-9cf0-1df8b85c49a1.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['cytoplasm', 'dermis']",
"noisy_text": " appearance, a round oval nuclei and a moderate amount of cytoplasm. And then we have nest cords and strands of otherwise banal appearing or banal appearing melanocytes present within the underlying dermis. There is evidence of maturation with depth in these sections, and no mitotic pairs. In the central portion of the specimen, you can see that the dermis is a little more sclerotic. And we've got the presence of separately heavily pigmented melanovagias. And then if we look at our top piece of tissue, again, we have the more banal appearing melanocytes out of the periphery. And centrally, we've got embedded within a sclerotic stroma a second distinct morphologic population of melanocytes. Some of these are dendritic, others have spindled or fusiform-shaped",
"corrected_text": " appearance, a round oval nuclei and a moderate amount of cytoplasm. And then we have nest cords and strands of otherwise banal appearing or banal appearing melanocytes present within the underlying dermis. There is evidence of maturation with depth in these sections, and no mitotic pairs. In the central portion of the specimen, you can see that the dermis is a little more sclerotic. And we've got the presence of separately heavily pigmented melanovagias. And then if we look at our top piece of tissue, again, we have the more banal appearing melanocytes out of the periphery. And centrally, we've got embedded within a sclerotic stroma a second distinct morphologic population of melanocytes. Some of these are dendritic, others have spindle-shaped or fusiform-shaped",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'specimen', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'banal', 'concept_id': 'C0004722', 'confidence': 0.7279530763626099}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}], [{'entity': 'Evidence', 'concept_id': 'C3887511', 'confidence': 1.0}, {'entity': 'maturation', 'concept_id': 'C0678723', 'confidence': 1.0}, {'entity': 'depth', 'concept_id': 'C0205125', 'confidence': 1.0}, {'entity': 'mitotic', 'concept_id': 'C1513354', 'confidence': 1.0}, {'entity': 'pairs', 'concept_id': 'C0600436', 'confidence': 0.8094210028648376}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'heavily', 'concept_id': 'C0337678', 'confidence': 0.6902515292167664}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'melanophages', 'concept_id': 'C3280463', 'confidence': 0.9375340938568115}], [{'entity': 'Sclerotic', 'concept_id': 'C0036429', 'confidence': 0.9999999403953552}, {'entity': 'stroma', 'concept_id': 'C0927195', 'confidence': 1.0}, {'entity': 'morphologic population', 'concept_id': 'C0543482', 'confidence': 0.699425995349884}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_311",
"caption_rating": "8"
},
{
"": "1008696",
"caption": "Clefting between epithelium and stroma is not seen in these lesions, unlike basal cell carcinoma.",
"image_path": "LlPaENuqzVQ_image_149214c6-8962-445f-97b4-994109a88c61.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['Trichofolliculoma with a cyst and miniaturized hair follicles', 'fibrous stroma', 'clefting between epithelium and stroma', 'clefting between epithelium and stroma']",
"noisy_text": " This is sort of a tricofolliculoma cut adjacent to the really the central cyst. And the tricofolliculoma has got a little cyst with these little miniaturized hair follicles that are radiating from the central cyst component of the lesion. So this is off to the side of it. But you can see that these follicular neoplasms, they pretty much commonly do have this stroma that you see with it that's more fibrous as opposed to fibromucinous. And that's helpful. It's not a criterion for the diagnosis necessarily every time, but it's a helpful finding when you see it because you don't usually get clefting between the epithelium and the stroma in these lesions as opposed to a basal cell carcinoma where you do. So that's a tricofolliculoma kind of cut to the side. OK, let's",
"corrected_text": " This is sort of a trichofolliculoma cut adjacent to the really the central cyst. And the trichofolliculoma has got a little cyst with these little miniaturized hair follicles that are radiating from the central cyst component of the lesion. So this is off to the side of it. But you can see that these follicular neoplasms, they pretty much commonly do have this stroma that you see with it that's more fibrous as opposed to fibromyxoid. And that's helpful. It's not a criterion for the diagnosis necessarily every time, but it's a helpful finding when you see it because you don't usually get clefting between the epithelium and the stroma in these lesions as opposed to a basal cell carcinoma where you do. So that's a trichofolliculoma kind of cut to the side. OK, let's",
"med_umls_ids": "[[{'entity': 'Trichofolliculoma', 'concept_id': 'C0334262', 'confidence': 1.0}, {'entity': 'cyst', 'concept_id': 'C0010709', 'confidence': 1.0}, {'entity': 'miniaturized hair follicles', 'concept_id': 'C0221971', 'confidence': 0.7287319302558899}, {'entity': 'adjacent', 'concept_id': 'C0205117', 'confidence': 1.0}, {'entity': 'central cyst', 'concept_id': 'C0205099', 'confidence': 0.7124271988868713}], [{'entity': 'Follicular', 'concept_id': 'C0439682', 'confidence': 1.0}, {'entity': 'neoplasms', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'fibrous stroma', 'concept_id': 'C1180207', 'confidence': 0.8035051226615906}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'Clefting', 'concept_id': 'C4021813', 'confidence': 0.8906428217887878}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'stroma', 'concept_id': 'C0927195', 'confidence': 1.0}, {'entity': 'lesions', 'concept_id': 'C0221198', 'confidence': 1.0}, {'entity': 'basal cell carcinoma', 'concept_id': 'C0007117', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_312",
"caption_rating": "8"
},
{
"": "1008896",
"caption": "Perineurioma and low-grade fibromyxoid sarcoma can be histologic mimics of this tumor.",
"image_path": "QDb68_G1HR4_image_4097825f-1098-41ce-81f2-a72d488bacdf.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['fine delicate thread-like collagen', 'spindle cells', 'perineurioma', 'low-grade fibromyxoid sarcoma', 'whirled or swirled areas']",
"noisy_text": " look at that very fine delicate thread-like collagen in the background, the spindle cells are very thin and bland and sometimes if you depending on which way the cells are kind of sectioned, they can look a little more oval or even round and I think this is similar that's why this tumor one of the mimics that you can see one of the histologic mimics is perineurioma and I have another video about perineurioma that really goes into detail. Perineuriomas often have cells that look very much like this and both perineurioma as well as low-grade fibromyxoid sarcoma can have very whirled or swirled areas. This one's",
"corrected_text": " look at that very fine delicate thread-like collagen in the background, the spindle cells are very thin and bland and sometimes if you depending on which way the cells are kind of sectioned, they can look a little more oval or even round and I think this is similar that's why this tumor one of the mimics that you can see one of the histologic mimics is perineurioma and I have another video about perineurioma that really goes into detail. Perineuriomas often have cells that look very much like this and both perineurioma as well as low-grade fibromyxoid sarcoma can have very whirled or swirled areas. This one's",
"med_umls_ids": "[[{'entity': 'background', 'concept_id': 'C1706907', 'confidence': 1.0}, {'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'delicate', 'concept_id': 'C0241181', 'confidence': 0.7745490074157715}, {'entity': 'thread-like collagen', 'concept_id': 'C1979891', 'confidence': 0.845443606376648}], [{'entity': 'spindle cells', 'concept_id': 'C0682540', 'confidence': 1.0}, {'entity': 'thin', 'concept_id': 'C0205168', 'confidence': 1.0}, {'entity': 'bland', 'concept_id': 'C0227475', 'confidence': 0.7435316443443298}, {'entity': 'oval', 'concept_id': 'C1709367', 'confidence': 1.0}, {'entity': 'round', 'concept_id': 'C0332490', 'confidence': 1.0}, {'entity': 'angle of sectioning', 'concept_id': 'C0700320', 'confidence': 0.7131970524787903}], [{'entity': 'Perineurioma', 'concept_id': 'C0751691', 'confidence': 0.9999999403953552}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'histologic', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'mimics', 'concept_id': 'C0393040', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_313",
"caption_rating": "8"
},
{
"": "1008899",
"caption": "Whirling pattern can be seen in perineurioma and dermatofibrosarcoma protuberans (DFSP).",
"image_path": "QDb68_G1HR4_image_a313915e-be10-4a8c-aad9-4213e6f88f34.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['whirling pattern']",
"noisy_text": " This one's not really showing that but some of them do, they have a lot of whirling pattern. So the two other things that keep in the differential here are perineurioma and also dermatofibrosarcoma protuberans, DFSP, which also has a tends to have a story form or whirled and swirled growth pattern and also has a translocation sarcoma, has very bland spindle cells. Okay, I guess I don't have any immunostains with me to show you today but just briefly the immunostains, most of the immunostains that we use for soft tissue tumors are negative most of the time in low-grade fibromyxoid sarcoma. CD34 is usually negative which is a pretty easy way to separate this from DFSP. The other thing is that low-grade fibromyxoid sarcoma usually is a relatively larger and deep, deep soft tissue below the fascia mass, although there are rare examples that are small and superficial and those seem to be more common in children. But DFSP is essentially always in the skin, the dermis or subcutaneous and rarely ever involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is",
"corrected_text": " This one's not really showing that but some of them do, they have a lot of whirling pattern. So the two other things that keep in the differential here are perineurioma and also dermatofibrosarcoma protuberans, DFSP, which also has a tends to have a story form or whirled and swirled growth pattern and also has a translocation sarcoma, has very bland spindle cells. Okay, I guess I don't have any immunostaining with me to show you today but just briefly the immunostaining, most of the immunostaining that we use for soft tissue tumors are negative most of the time in low-grade fibromyxoid sarcoma. CD34 is usually negative which is a pretty easy way to separate this from DFSP. The other thing is that low-grade fibromyxoid sarcoma usually is a relatively larger and deep, deep soft tissue below the fascia mass, although there are rare examples that are small and superficial and those seem to be more common in children. But DFSP is essentially always in the skin, the dermis or subcutaneous and rarely ever involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is",
"med_umls_ids": "[[{'entity': 'Whirling pattern', 'concept_id': 'C0449774', 'confidence': 0.6110570430755615}, {'entity': 'perineurioma', 'concept_id': 'C0751691', 'confidence': 0.9999999403953552}, {'entity': 'dermatofibrosarcoma protuberans', 'concept_id': 'C0206647', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}], [{'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}, {'entity': 'skin', 'concept_id': 'C0444099', 'confidence': 1.0}, {'entity': 'deep soft tissue', 'concept_id': 'C0225317', 'confidence': 0.7996832728385925}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_314",
"caption_rating": "8"
},
{
"": "1006702",
"caption": "Intraductal carcinoma of the prostate is associated with high-volume, high-grade invasive cancer.",
"image_path": "iklRyY1nBIE_image_6201890b-5220-4475-a935-214bc290131a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['positive lymph node', 'intraductal carcinoma', 'prostate', 'invasive cancer']",
"noisy_text": " there's actually a positive lymph node right there, see? So you can see there's no introductal carcinoma here, because it's impossible for an introductal process to metastasize. So the point I'm trying to make is introductal carcinoma of the prostate is associated with high-volume, high-grade invasive cancer next door that does all those bad things. So that's the message I'm trying to pass across. So this is a very good example of introductal carcinoma of the prostate with associated high-grade, high-volume invasive",
"corrected_text": " there's actually a positive lymph node right there, see? So you can see there's no intraductal carcinoma here, because it's impossible for an intracanalicular process to metastasize. So the point I'm trying to make is intraductal carcinoma of the prostate is associated with high-volume, high-grade invasive cancer next door that does all those bad things. So that's the message I'm trying to pass across. So this is a very good example of intraductal carcinoma of the prostate with associated high-grade, high-volume invasive",
"med_umls_ids": "[[{'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'lymph node', 'concept_id': 'C0024204', 'confidence': 1.0}], [{'entity': 'intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'intracystic', 'concept_id': 'C1708174', 'confidence': 0.8438851833343506}, {'entity': 'metastasize', 'concept_id': 'C0027627', 'confidence': 1.0}], [{'entity': 'Intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'associated with', 'concept_id': 'C0332281', 'confidence': 1.0}, {'entity': 'high-volume', 'concept_id': 'C3494218', 'confidence': 0.8583465814590454}, {'entity': 'high-grade invasive cancer', 'concept_id': 'C1512433', 'confidence': 0.6872689723968506}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_315",
"caption_rating": "9"
},
{
"": "1006283",
"caption": "Nodules around joints can be seen in gout, RA, and OE.",
"image_path": "udoW6VSqsm4_image_efe17185-babf-4805-a5af-7bc44ac4c0bc.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['Nodules on acral skin', 'Nodules around joints']",
"noisy_text": " You notice this is on acral skin. There are often nodules in that area, and they can start off as palpable purpura in some cases. So, it's like, you know, regular leukocytoplastic vasculitis that can end up with these nodular lesions. Next slide. What is the histologic identical twin of this process? The granulomyphial. Yes, excellent. Granulomyphial looks very, very similar to this on the microscope. Obviously, clinically, it's not like this. It's on the face. It's on the pseudolymphoma. Next slide. So, this is a type of chronic vasculitis that ends up forming these fibrotic nodules. It's an interesting condition, and it is thought to be associated with other conditions. So, you want to make sure that you don't just, next case. A lot of times, these things can give you cholesterol clefts. One of the old names for this years ago used to be extracellular cholesterolosis, and it would give you these, all these neutrophils would gradually degranulate, if you will. The neutrophil products would have lipid in them, and you'd get these cholesterol clefts that would look kind of yellowish. Now, what are a couple other clinical diseases where you can see nodules around joints? You know, like, gout, RA, OE. Good. Gout, RA. There's",
"corrected_text": " You notice this is on acral skin. There are often nodules in that area, and they can start off as palpable purpura in some cases. So, it's like, you know, leukocytoclastic vasculitis that can end up with these nodular lesions. Next slide. What is the histologic identical twin of this process? The granuloma faciale. Yes, excellent. granuloma faciale looks very, very similar to this on the microscope. Obviously, clinically, it's not like this. It's on the face. It's on the pseudolymphoma. Next slide. So, this is a type of chronic vasculitis that ends up forming these fibrotic nodules. It's an interesting condition, and it is thought to be associated with other conditions. So, you want to make sure that you don't just, next case. A lot of times, these things can give you cholesterol clefts. One of the old names for this years ago used to be extracellular cholesterolosis, and it would give you these, all these neutrophils would gradually degranulate, if you will. The neutrophil products would have lipid in them, and you'd get these cholesterol clefts that would look kind of yellowish. Now, what are a couple other clinical diseases where you can see nodules around joints? You know, like, gout, RA, OE. Good. Gout, RA. There's",
"med_umls_ids": "[[{'entity': 'Nodules', 'concept_id': 'C0028259', 'confidence': 1.0}, {'entity': 'acral skin', 'concept_id': 'C0444099', 'confidence': 0.7122198939323425}, {'entity': 'leukocytoclastic vasculitis', 'concept_id': 'C0151436', 'confidence': 1.0}, {'entity': 'nodular', 'concept_id': 'C0205297', 'confidence': 1.0}, {'entity': 'lesions', 'concept_id': 'C0221198', 'confidence': 1.0}], [{'entity': 'Granuloma faciale', 'concept_id': 'C0239495', 'confidence': 1.0}, {'entity': 'histologic', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'identical', 'concept_id': 'C0205280', 'confidence': 1.0}, {'entity': 'twin', 'concept_id': 'C0041427', 'confidence': 0.9999999403953552}, {'entity': 'process', 'concept_id': 'C1184743', 'confidence': 1.0}], [{'entity': 'Granuloma faciale', 'concept_id': 'C0239495', 'confidence': 1.0}, {'entity': 'leukocytoclastic vasculitis', 'concept_id': 'C0151436', 'confidence': 1.0}, {'entity': 'microscope', 'concept_id': 'C0181839', 'confidence': 1.0}], [{'entity': 'Chronic vasculitis', 'concept_id': 'C0042384', 'confidence': 0.7992802858352661}, {'entity': 'fibrotic nodules', 'concept_id': 'C0332561', 'confidence': 0.8351579308509827}], [{'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'associated with', 'concept_id': 'C0332281', 'confidence': 1.0}, {'entity': 'conditions', 'concept_id': 'C0012634', 'confidence': 0.8556983470916748}], [{'entity': 'Extracellular cholesterolosis', 'concept_id': 'C2973528', 'confidence': 0.9169934391975403}, {'entity': 'cholesterol clefts', 'concept_id': 'C3686582', 'confidence': 0.9999999403953552}, {'entity': 'yellowish nodules', 'concept_id': 'C1867455', 'confidence': 0.8135299682617188}], [{'entity': 'Nodules', 'concept_id': 'C0028259', 'confidence': 1.0}, {'entity': 'joints', 'concept_id': 'C0022417', 'confidence': 1.0}, {'entity': 'gout', 'concept_id': 'C0018099', 'confidence': 1.0}, {'entity': 'RA', 'concept_id': 'C0002893', 'confidence': 1.0}, {'entity': 'OE', 'concept_id': 'C1551089', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_316",
"caption_rating": "7"
},
{
"": "1008809",
"caption": "Spear adenoma is a glandular neoplasm that shows differentiation towards the secretory component of a gland.",
"image_path": "8S4LeiO6Bbk_image_ae5a7f91-b793-4d68-aae8-d47495618c20.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Two cell types, light and dark staining', 'Sprinkling of lymphocytes', 'Duct formation within the tumor', 'Edematous stroma', 'Spear adenoma']",
"noisy_text": " are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and a sprinkling of lymphocytes in concert with ducts in the tumor, and an edematous stroma are diagnostic of spear adenoma. And of course, this is one of the glandular neoplasm that shows differentiation towards the secretory component of this white gland. So very nice example here of",
"corrected_text": " are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and a sprinkling of lymphocytes in concert with ducts in the tumor, and an edematous stroma are diagnostic of spear adenoma. And of course, this is one of the glandular neoplasm that shows differentiation towards the secretory component of this white gland. So very nice example here of",
"med_umls_ids": "[[{'entity': 'Tumor cells', 'concept_id': 'C0431085', 'confidence': 1.0}, {'entity': 'dark', 'concept_id': 'C0332582', 'confidence': 0.9999999403953552}, {'entity': 'light staining', 'concept_id': 'C0487602', 'confidence': 0.7634408473968506}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}], [{'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}], [{'entity': 'Hints', 'concept_id': 'C1512348', 'confidence': 1.0}, {'entity': 'duct', 'concept_id': 'C0687028', 'confidence': 1.0}, {'entity': 'formation', 'concept_id': 'C0220781', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}], [{'entity': 'configuration', 'concept_id': 'C0449830', 'confidence': 1.0}, {'entity': 'cell types', 'concept_id': 'C0007634', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'ducts', 'concept_id': 'C0687028', 'confidence': 1.0}, {'entity': 'edematous stroma', 'concept_id': 'C1333376', 'confidence': 0.8675230145454407}, {'entity': 'diagnostic', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'spear adenoma', 'concept_id': 'C0001430', 'confidence': 0.7512055039405823}], [{'entity': 'Spear adenoma', 'concept_id': 'C0001430', 'confidence': 0.7512055039405823}, {'entity': 'glandular neoplasm', 'concept_id': 'C0205854', 'confidence': 1.0}, {'entity': 'differentiation', 'concept_id': 'C0007589', 'confidence': 1.0}, {'entity': 'secretory', 'concept_id': 'C1327616', 'confidence': 1.0}, {'entity': 'gland', 'concept_id': 'C1285092', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_317",
"caption_rating": "8"
},
{
"": "1006605",
"caption": "Presence of pronounced basal cell change along the DEJ, scattered dyskeratotic cells within the basal layer, and a patchy band-like infiltrate of lymphocytes within the papillary dermis, indicating a chronic process.",
"image_path": "8S4LeiO6Bbk_image_f44da027-db54-40c6-bdda-1d04c3a93681.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['basal cell change along the DEJ', 'melanophages with variable pigment size and shape']",
"noisy_text": " cornified layer but as we zoom in we can see that we've got pronounced bacular change along the DEJ, scattered dyskeratotic cells within the basal layer, and within the papillary dermis we have a patchy band-like infiltrate of lymphocytes and a few scattered melanophages within a papillary dermis that's somewhat thickened by coarse collagen, indicating that this is probably a long-standing process. Again, note all the melanophages here, and I'm going to zoom in again. One of the points we made with the hemocentaurotic dermatofibroma is that the pigment present within the histiocytes or the melanophages is variable in size and shape. Now look at the melanin granules within this melanophage, and you can see that they're much more uniform in size and shape. Now look at the melanin granules within this melanophage, and you can see that they're much more uniform in size than the",
"corrected_text": " cornified layer but as we zoom in we can see that we've got pronounced basal cell change along the DEJ, scattered dyskeratotic cells within the basal layer, and within the papillary dermis we have a patchy band-like infiltrate of lymphocytes and a few scattered melanocytes within a papillary dermis that's somewhat thickened by coarse collagen, indicating that this is probably a chronic process. Again, note all the melanophages here, and I'm going to zoom in again. One of the points we made with the hemocentaurotic dermatofibroma is that the pigment present within the histiocytes or the melanophages is variable in size and shape. Now look at the melanin granules within this melanophage, and you can see that they're much more uniform in size and shape. Now look at the melanin granules within this melanophage, and you can see that they're much more uniform in size than the",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'basal cell', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'DEJ', 'concept_id': 'C0385794', 'confidence': 0.5962325930595398}, {'entity': 'scattered', 'concept_id': 'C0439742', 'confidence': 1.0}, {'entity': 'dyskeratotic cells', 'concept_id': 'C1512098', 'confidence': 0.8970272541046143}, {'entity': 'basal layer', 'concept_id': 'C0221925', 'confidence': 1.0}, {'entity': 'patchy', 'concept_id': 'C0205413', 'confidence': 1.0}, {'entity': 'band-like infiltrate', 'concept_id': 'C0332448', 'confidence': 0.6589096188545227}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'papillary dermis', 'concept_id': 'C0682598', 'confidence': 1.0}, {'entity': 'chronic process', 'concept_id': 'C0205191', 'confidence': 0.7250075340270996}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'melanophages', 'concept_id': 'C3280463', 'confidence': 0.9375340938568115}, {'entity': 'variable', 'concept_id': 'C0439828', 'confidence': 1.0}, {'entity': 'pigment size', 'concept_id': 'C0031911', 'confidence': 0.7176747918128967}, {'entity': 'shape', 'concept_id': 'C0332479', 'confidence': 1.0}], [{'entity': 'Uniform size', 'concept_id': 'C0205375', 'confidence': 0.7298805713653564}, {'entity': 'shape', 'concept_id': 'C0332479', 'confidence': 1.0}, {'entity': 'melanin granules', 'concept_id': 'C0230692', 'confidence': 0.9174172878265381}, {'entity': 'melanophage', 'concept_id': 'C3280463', 'confidence': 0.8030633330345154}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_318",
"caption_rating": "9"
},
{
"": "1006562",
"caption": "Smooth muscle bundles are infiltrated by lymphomatous cells in the wall of the small bowel, causing abnormal appearance and ulceration of the mucosa.",
"image_path": "gcLu6sNtYoc_image_8adc79e0-8010-43ae-9d68-b581f21e28ee.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Hematopathology', 'Gastrointestinal', 'Pulmonary']",
"roi_text": "['smooth muscle bundles', 'lymphomatous cells', 'wall of the small bowel', 'ulceration of the mucosa', 'fibrinoid inflammatory ulcer exudate', 'GI bleeding', 'smooth muscle bundles', 'lymphomatous cells', 'wall of the small bowel', 'ulceration of the mucosa', 'fibrinoid inflammatory ulcer exudate', 'GI bleeding']",
"noisy_text": " see some smooth muscle bundles here, but this is very much infiltrated by lymphomatous cells, and then of course, we have the serosa. So we can see that there is a very abnormal infiltrate of this bluish appearing cells throughout the wall of the small bowel. In some areas, it is full thickness. In other areas, it just involves part of the wall, and in fact, in this area, we can see that this has caused ulceration of the mucosa. There is this fibrinoid inflammatory ulcer exudate here, and of course, this means that it can give rise to GI bleeding. Taking a",
"corrected_text": " see some smooth muscle bundles here, but this is very much infiltrated by lymphomatous cells, and then of course, we have the serosa. So we can see that there is a very abnormal infiltrate of this bluish appearing cells throughout the wall of the small bowel. In some areas, it is full thickness. In other areas, it just involves part of the wall, and in fact, in this area, we can see that this has caused ulceration of the mucosa. There is this fibrinoid inflammatory ulcer exudate here, and of course, this means that it can give rise to GI bleeding. Taking a",
"med_umls_ids": "[[{'entity': 'Smooth muscle', 'concept_id': 'C1267092', 'confidence': 1.0}, {'entity': 'bundles', 'concept_id': 'C3658308', 'confidence': 0.8706014752388}, {'entity': 'infiltrated', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'lymphomatous cells', 'concept_id': 'C0883208', 'confidence': 0.8273725509643555}, {'entity': 'wall', 'concept_id': 'C0677535', 'confidence': 1.0}, {'entity': 'small bowel', 'concept_id': 'C0021852', 'confidence': 1.0}, {'entity': 'abnormal', 'concept_id': 'C0205161', 'confidence': 1.0}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'ulceration', 'concept_id': 'C0041582', 'confidence': 1.0}, {'entity': 'mucosa', 'concept_id': 'C0026724', 'confidence': 1.0}], [{'entity': 'abnormal', 'concept_id': 'C0205161', 'confidence': 1.0}, {'entity': 'GI bleeding', 'concept_id': 'C0017181', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "644.0",
"width": "1280.0",
"id": "test_319",
"caption_rating": "9"
},
{
"": "1007664",
"caption": "The presence of more than five neutrophils or more than 15 eosinophils per high power field in the lamina propria is indicative of eosinophilic gastritis, esophagitis, enteritis, or colitis.",
"image_path": "r7OA0Trj5hQ_image_e0cc5063-6799-42a7-b30e-d112cb172cc6.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Cryptitis', 'Cryptitis', 'Crypt abscess', 'Variation in gland size, shape, and distribution.', 'Variation in gland size, shape, and distribution.']",
"noisy_text": " Remember I told you if you see more than five neutrophils, more than five eosinophils sitting in the lamina propria or more than 15 eosinophils per high power field, that is a eosinophilic gastritis, if it is from the stomach. If it is esophagus, it is eosinophilic esophagitis, eosinophilic entritis, eosinophilic colitis. So eosinophilic gastroenteritis. Here it is a cryptitis and cryptopsis. And the glands are also pushed well apart. The glands are showing variation in size, shape, distribution. So this is chronic colitis with activity.",
"corrected_text": " Remember I told you if you see more than five neutrophils, more than five eosinophils sitting in the lamina propria or more than 15 eosinophils per high power field, that is a eosinophilic gastritis, if it is from the stomach. If it is esophagus, it is eosinophilic esophagitis, eosinophilic enteritis, eosinophilic colitis. So eosinophilic gastroenteritis. Here it is a cryptitis and crypt abscess. And the glands are also pushed well apart. The glands are showing variation in size, shape, distribution. So this is chronic colitis with activity.",
"med_umls_ids": "[[{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'eosinophilic gastritis', 'concept_id': 'C0267154', 'confidence': 1.0}, {'entity': 'esophagitis', 'concept_id': 'C0014868', 'confidence': 1.0}, {'entity': 'enteritis', 'concept_id': 'C0014335', 'confidence': 1.0}, {'entity': 'colitis', 'concept_id': 'C0009319', 'confidence': 1.0}], [{'entity': 'cryptitis', 'concept_id': 'C1394254', 'confidence': 0.9999998807907104}, {'entity': 'crypt', 'concept_id': 'C1880192', 'confidence': 1.0}, {'entity': 'abscess', 'concept_id': 'C0000833', 'confidence': 1.0}, {'entity': 'inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}, {'entity': 'area', 'concept_id': 'C0017446', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_320",
"caption_rating": "9"
},
{
"": "1009080",
"caption": "A patient with chlamydia was misdiagnosed as IBD and developed a rectal stricture due to improper treatment.",
"image_path": "sDFjOtMAYrk_image_65b6c43f-9a35-4a19-a5af-aab14165c2f2.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['Rectum', 'Chlamydia', 'Immunostain']",
"noisy_text": " process and getting them the proper antibiotics. Many of these cases, especially when we were starting to recognize them, both clinicians and some pathologists were leaning towards IBD. And I had one or two cases that were treated as IBD for a certain period of time, specifically I'm remembering a patient with chlamydia and he developed a stricture in the rectum because he wasn't treated properly. This was syphilis. For chlamydia, there's no immunostain. Actually, I misspoke. There is an immunostain. I think the CDC uses it, but it's not available for massive consumption.",
"corrected_text": " process and getting them the proper antibiotics. Many of these cases, especially when we were starting to recognize them, both clinicians and some pathologists were leaning towards IBD. And I had one or two cases that were treated as IBD for a certain period of time, specifically I'm remembering a patient with chlamydia and he developed a stricture in the rectum because he wasn't treated properly. This was syphilis. For chlamydia, there's no immunostain. Actually, I misspoke. There is an immunostain. I think the CDC uses it, but it's not available for massive consumption.",
"med_umls_ids": "[[{'entity': 'antibiotics', 'concept_id': 'C0003232', 'confidence': 1.0}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'IBD', 'concept_id': 'C0021390', 'confidence': 1.0}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'chlamydia', 'concept_id': 'C0008148', 'confidence': 1.0}, {'entity': 'misdiagnosed', 'concept_id': 'C0679838', 'confidence': 0.896425724029541}, {'entity': 'IBD', 'concept_id': 'C0021390', 'confidence': 1.0}, {'entity': 'rectal stricture', 'concept_id': 'C0267582', 'confidence': 1.0}, {'entity': 'improper treatment', 'concept_id': 'C0039798', 'confidence': 0.7291568517684937}], [{'entity': 'Immunostain', 'concept_id': 'C1441614', 'confidence': 0.7340688109397888}, {'entity': 'chlamydia', 'concept_id': 'C0008148', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_321",
"caption_rating": "7"
},
{
"": "1006791",
"caption": "Moderate amount of amphiphilic cytoplasm.",
"image_path": "j_rG5XPImFQ_image_4983899f-27fa-4020-a5f1-1a3ae726f6bd.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Hematopathology', 'Breast pathology']",
"roi_text": "['nucleolus', 'myofibroblasts', 'myositis ossificans']",
"noisy_text": " nucleolus, and a moderate amount of amphiphilic cytoplasm. Now, at first glance, you might think these cells look a bit weird, and that might make you worry about a sarcoma, such as osteosarcoma. However, you'll come to recognize that this pattern in morphology you see here is really characteristic of myofibroblasts. This is an example of myocytosocificans, a benign myofibroblastic neoplasm that is part of the USP6 rearranged family of tumors, which includes, among others, nodular fasciitis and aneurysmal bone cyst. These are",
"corrected_text": " nucleolus, and a moderate amount of amphiphilic cytoplasm. Now, at first glance, you might think these cells look a bit weird, and that might make you worry about a sarcoma, such as osteosarcoma. However, you'll come to recognize that this pattern in morphology you see here is really characteristic of myofibroblasts. This is an example of myositis ossificans, a benign myofibroblastic neoplasm that is part of the USP6 rearranged family of tumors, which includes, among others, nodular fasciitis and aneurysmal bone cyst. These are",
"med_umls_ids": "[[{'entity': 'Moderate', 'concept_id': 'C0205081', 'confidence': 1.0}, {'entity': 'amount', 'concept_id': 'C1265611', 'confidence': 0.9999998807907104}, {'entity': 'amphiphilic', 'concept_id': 'C0596084', 'confidence': 0.8564908504486084}, {'entity': 'cytoplasm', 'concept_id': 'C0010834', 'confidence': 1.0}], [{'entity': 'Characteristic', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}, {'entity': 'myofibroblasts', 'concept_id': 'C0225360', 'confidence': 1.0}], [{'entity': 'Myositis ossificans', 'concept_id': 'C0027122', 'confidence': 0.9999999403953552}, {'entity': 'benign', 'concept_id': 'C0205183', 'confidence': 1.0}, {'entity': 'USP6', 'concept_id': 'C1175888', 'confidence': 1.0}, {'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_322",
"caption_rating": "8"
},
{
"": "1006268",
"caption": "Large vascular channels in the chorion filled with blood.",
"image_path": "PJX3uZ7fRn4_image_6e06942c-9cdd-4403-a87b-fb8b5258284b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gynecologic', 'Soft tissue', 'Hematopathology']",
"roi_text": "['vascular channels', 'chorionic villi', 'calcification', 'vascular channels', 'chorionic villi', 'calcification']",
"noisy_text": " This is a section from placenta which shows a large irregular area with proliferation of thin walled vascular channels of variable size towards the fetal surface of placenta. Smaller chorionic villi can be seen towards the maternal site. Higher magnification of the same showing large vascular channels in the chorion filled with blood. Still higher magnification showing intercommunicating slit-like vascular spaces in the mass. Focal area of calcification can be seen in the tumor. Still another area",
"corrected_text": " This is a section from placenta which shows a large irregular area with proliferation of thin walled vascular channels of variable size towards the fetal surface of placenta. smaller chorionic villi are not incorrect can be seen towards the maternal site. Higher magnification of the same showing large vascular channels in the chorion filled with blood. Still higher magnification showing intercommunicating slit-like vascular spaces in the mass. Focal area of calcification can be seen in the tumor. Still another area",
"med_umls_ids": "[[{'entity': 'Proliferation', 'concept_id': 'C0334094', 'confidence': 1.0}, {'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}, {'entity': 'variable size', 'concept_id': 'C1866144', 'confidence': 0.8559831976890564}, {'entity': 'fetal', 'concept_id': 'C0015965', 'confidence': 1.0}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'placenta', 'concept_id': 'C0032043', 'confidence': 1.0}], [{'entity': 'chorionic villi', 'concept_id': 'C0008508', 'confidence': 1.0}, {'entity': 'maternal site', 'concept_id': 'C0026591', 'confidence': 0.7640593647956848}], [{'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}, {'entity': 'chorion', 'concept_id': 'C0008503', 'confidence': 0.9999998807907104}, {'entity': 'blood', 'concept_id': 'C0005767', 'confidence': 1.0}], [{'entity': 'Intercommunicating', 'concept_id': 'C0205196', 'confidence': 0.8271207213401794}, {'entity': 'vascular spaces', 'concept_id': 'C0225983', 'confidence': 0.819495439529419}, {'entity': 'mass', 'concept_id': 'C0577559', 'confidence': 1.0}], [{'entity': 'Focal area', 'concept_id': 'C0205234', 'confidence': 0.7634891271591187}, {'entity': 'calcification', 'concept_id': 'C0006660', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_323",
"caption_rating": "8"
},
{
"": "1005407",
"caption": "Presence of luminal ruffling in prostate glands is a reassuring sign as prostate cancer usually has sharp luminal borders.",
"image_path": "iklRyY1nBIE_image_00927d48-7249-4c31-a7a8-1dda7d03a057.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['luminal ruffling', 'prostate glands', 'early corpora and mucin formation', 'atrophic gland', 'luminal ruffling', 'prostate glands', 'early corpora and mucin formation', 'atrophic gland']",
"noisy_text": " And if you go a bit closer, you can see that they have a little bit of luminal ruffling. When you see luminal ruffling, that should make you feel a little bit more comfortable, because prostate cancer usually has sharp luminal borders. The problem is the previous case I showed you actually had sharp luminal borders, even though it was partial atrophy. So that's what makes this tricky. But in this case, you can see the fairly well circumscribed, one of the glands even has a little bit of early corpora and malatial formation. But you also have this gland over here that looks somewhat similar, but a little bit more atrophic. And if you look at the corresponding immunosuchemical stain and that focus of interest, we'll see what happens. So again, this",
"corrected_text": " And if you go a bit closer, you can see that they have a little bit of luminal ruffling. When you see luminal ruffling, that should make you feel a little bit more comfortable, because prostate cancer usually has sharp luminal borders. The problem is the previous case I showed you actually had sharp luminal borders, even though it was partial atrophy. So that's what makes this tricky. But in this case, you can see the fairly well circumscribed, one of the glands even has a little bit of early corpora and mucin formation. But you also have this gland over here that looks somewhat similar, but a little bit more atrophic. And if you look at the corresponding immunohistochemical stain and that focus of interest, we'll see what happens. So again, this",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'luminal ruffling', 'concept_id': 'C3269125', 'confidence': 0.690064549446106}, {'entity': 'prostate glands', 'concept_id': 'C0033572', 'confidence': 0.8152219653129578}, {'entity': 'prostate cancer', 'concept_id': 'C0376358', 'confidence': 1.0}, {'entity': 'luminal borders', 'concept_id': 'C0524462', 'confidence': 0.6706532835960388}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_324",
"caption_rating": "9"
},
{
"": "1008621",
"caption": "Presence of acinar structures resembling pancreas in the stomach is known as pancreatic acinar metaplasia.",
"image_path": "r7OA0Trj5hQ_image_f34ec1bf-1a92-4201-8a31-1e8831252218.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Acinar structures resembling pancreas in the stomach', 'Peritoneal cells in gastric fundic mucosa or gastric corpus mucosa', 'Acinar structures resembling pancreas in the stomach', 'Pancreatic acinar-like structures in the GIT']",
"noisy_text": " These are the peritoneal cells. When you don't see the peritoneal cells in the gastric fundic mucosa or gastric corpus mucosa, then you have to call it as pyloric metaplasia. This is very, very important because you see it in autoimmune gastritis. Sometimes the stomach can show acinar structures resembling pancreas. Then it is known as pancreatic acinar metaplasia. This can also happen in the small intestine. There, when you do staining for amylase or trypsin, it will be positive, but on H&E itself, you can see pancreatic acinar-like structures in the GIT. Then it will become pancreatic acinar metaplasia. Here is the",
"corrected_text": " These are the peritoneal cells. When you don't see the peritoneal cells in the gastric fundic mucosa or gastric corpus mucosa, then you have to call it as pyloric metaplasia. This is very, very important because you see it in autoimmune gastritis. Sometimes the stomach can show acinar structures resembling pancreas. Then it is known as pancreatic acinar metaplasia. This can also happen in the small intestine. There, when you do staining for amylase or trypsin, it will be positive, but on H&E itself, you can see pancreatic acinar-like structures in the GIT. Then it will become pancreatic acinar metaplasia. Here is the",
"med_umls_ids": "[[{'entity': 'Absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'peritoneal cells', 'concept_id': 'C0031153', 'confidence': 0.7749612331390381}, {'entity': 'gastric fundic mucosa', 'concept_id': 'C0017136', 'confidence': 0.8429272770881653}, {'entity': 'gastric corpus mucosa', 'concept_id': 'C0735811', 'confidence': 0.9813486337661743}, {'entity': 'pyloric metaplasia', 'concept_id': 'C4288813', 'confidence': 0.8951747417449951}, {'entity': 'autoimmune gastritis', 'concept_id': 'C3887639', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'acinar structures', 'concept_id': 'C0678594', 'confidence': 0.7908228039741516}, {'entity': 'pancreas', 'concept_id': 'C0030274', 'confidence': 0.9999999403953552}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'pancreatic acinar metaplasia', 'concept_id': 'C4021967', 'confidence': 0.7844848036766052}], [{'entity': 'Pancreatic acinar metaplasia', 'concept_id': 'C4021967', 'confidence': 0.7844848036766052}, {'entity': 'small', 'concept_id': 'C0700321', 'confidence': 0.9999998807907104}, {'entity': 'intestine', 'concept_id': 'C0021853', 'confidence': 1.0}, {'entity': 'staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'amylase', 'concept_id': 'C0002712', 'confidence': 1.0}, {'entity': 'trypsin', 'concept_id': 'C0041236', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_325",
"caption_rating": "8"
},
{
"": "1005207",
"caption": "Muscle should only be present in the muscularis mucosa, but hyperplasia can cause muscle bundles to extend into the lamina propria.",
"image_path": "r7OA0Trj5hQ_image_5eb1593c-a2f1-493d-b339-0054c108ae6a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Muscle coming in the lamina propria', 'Muscularis mucosa is hyperplastic', 'Muscle coming in the lamina propria', 'Muscularis mucosa is hyperplastic', 'Muscularis mucosa is hyperplastic']",
"noisy_text": " The epithelium, the glands are pushed apart each other. And this may be procedure related. This may be seen in chemical gastritis, lamina propria. It's a very nonspecific finding, not diagnostic of anything. But whenever you see, think of chemical gastritis. This is muscularization. You see in the hyperwire, muscle coming in the lamina propria. Lamina propria should be free of musculature. The muscle should be there only in the muscularis mucosa. Here in this low power, you can see the muscularis mucosa is hyperplastic. And it is sending the muscle bundle into the lamina propria. This happens in chemical gastritis in case of stomach and in",
"corrected_text": " The epithelium, the glands are pushed apart each other. And this may be procedure related. This may be seen in chemical gastritis, lamina propria. It's a very nonspecific finding, not diagnostic of anything. But whenever you see, think of chemical gastritis. This is muscularization. You see in the hyperplasia, muscle coming in the lamina propria. Lamina propria should be free of musculature. The muscle should be there only in the muscularis mucosa. Here in this low power, you can see the muscularis mucosa is hyperplastic. And it is sending the muscle bundle into the lamina propria. This happens in chemical gastritis in case of stomach and in",
"med_umls_ids": "[[{'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'procedure-related', 'concept_id': 'C2924519', 'confidence': 1.0}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}], [{'entity': 'Muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'nonspecific', 'concept_id': 'C0750540', 'confidence': 1.0}, {'entity': 'finding', 'concept_id': 'C0037088', 'confidence': 1.0}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}], [{'entity': 'Muscle', 'concept_id': 'C0026845', 'confidence': 1.0}, {'entity': 'muscularis mucosa', 'concept_id': 'C0225357', 'confidence': 0.9999998807907104}, {'entity': 'hyperplasia', 'concept_id': 'C0020507', 'confidence': 1.0}, {'entity': 'muscle bundles', 'concept_id': 'C0504095', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}], [{'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_326",
"caption_rating": "8"
},
{
"": "1008705",
"caption": "Double cuboidal layer with a small lumen lined by pink cuticle that spirals up and out through the surface, allowing sweat to come out to the surface.",
"image_path": "pheenISyPWk_image_5ccf4240-3b41-4b73-9794-9866f7eab835.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['Double cuboidal layer with a small lumen lined by pink cuticle', 'Spiraling duct', 'Corneal layer', 'Structure that allows sweat to come out to the surface']",
"noisy_text": " double cuboidal layer with a little lumen lined by pink cuticle, it eventually comes up and empties into the surface, and when it does, you can see it kind of spirals, this is all one duct that's kind of spiraling, we're just cutting through part of the spiral, and it spirals up and out through the surface, and that's still the space there, even going through the corneal layer that allows the sweat to come out to the surface. So when you get sweaty feet or sweaty palms, this is how it's happening, and so this structure is called",
"corrected_text": " double cuboidal layer with a little lumen lined by pink cuticle, it eventually comes up and empties into the surface, and when it does, you can see it kind of spirals, this is all one duct that's kind of spiraling, we're just cutting through part of the spiral, and it spirals up and out through the surface, and that's still the space there, even going through the corneal layer that allows the sweat to come out to the surface. So when you get sweaty feet or sweaty palms, this is how it's happening, and so this structure is called",
"med_umls_ids": "[[{'entity': 'Double cuboidal layer', 'concept_id': 'C1856923', 'confidence': 0.5985994338989258}, {'entity': 'lumen', 'concept_id': 'C0524461', 'confidence': 0.9999998807907104}, {'entity': 'pink', 'concept_id': 'C0332585', 'confidence': 1.0}, {'entity': 'cuticle', 'concept_id': 'C2699479', 'confidence': 1.0}, {'entity': 'spirals', 'concept_id': 'C0860888', 'confidence': 0.8691306710243225}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'sweat', 'concept_id': 'C0038984', 'confidence': 1.0}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_327",
"caption_rating": "8"
},
{
"": "1004180",
"caption": "Presence of lymphocytes and plasma cells is not a feature of chronicity, but architectural changes in gland size, shape, and distribution indicate chronicity.",
"image_path": "r7OA0Trj5hQ_image_7357e616-a846-495b-9c61-7830aeba911b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Neutrophils in the epithelium indicating cryptitis', 'Gastric biopsy for H. pylori with crypt abscess']",
"noisy_text": " Please remember, presence of lymphocytes and plasma cells is not a feature of chronicity. But architectural change by the way of irregular size, shape, and distributed glands is an indication of chronicity. Criteria for chronicity. Yeah, you see nicely neutrophils sitting in the epithelium. Can you all see neutrophils sitting in the epithelium? So this is cryptitis. It is stomach, even though I'm using the term. But I just want to know whether you are able to understand or not. This is a gastric biopsy where you have to look for H. pylori because the H. pylori secrete some chemotactic factors for neutrophils. That's why the neutrophils come. And this is a crypt abscess. This is",
"corrected_text": " Please remember, presence of lymphocytes and plasma cells is not a feature of chronicity. But architectural change by the way of irregular size, shape, and distributed glands is an indication of chronicity. Criteria for chronicity. Yeah, you see nicely neutrophils sitting in the epithelium. Can you all see neutrophils sitting in the epithelium? So this is cryptitis. It is stomach, even though I'm using the term. But I just want to know whether you are able to understand or not. This is a gastric biopsy where you have to look for H. pylori because the H. pylori secrete some chemotactic factors for neutrophils. That's why the neutrophils come. And this is a crypt abscess. This is",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'chronicity', 'concept_id': 'C0547045', 'confidence': 1.0}, {'entity': 'architectural', 'concept_id': 'C0003737', 'confidence': 0.8758222460746765}, {'entity': 'changes', 'concept_id': 'C0392747', 'confidence': 1.0}, {'entity': 'gland size', 'concept_id': 'C0426336', 'confidence': 0.8790121674537659}, {'entity': 'shape', 'concept_id': 'C0332479', 'confidence': 1.0}, {'entity': 'distribution', 'concept_id': 'C0037775', 'confidence': 1.0}, {'entity': 'chronicity', 'concept_id': 'C0547045', 'confidence': 1.0}], [{'entity': 'Neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'cryptitis', 'concept_id': 'C1394254', 'confidence': 0.9999998807907104}, {'entity': 'H. pylori infection', 'concept_id': 'C0850666', 'confidence': 0.9999999403953552}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_328",
"caption_rating": "8"
},
{
"": "1004199",
"caption": "DFSP may not always have a typical storiform pattern.",
"image_path": "LlPaENuqzVQ_image_76a5b714-55f4-4548-a00f-fcd28a02bf2a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['diffuse pattern between and among lipocytes', 'typical storiform pattern', 'ring chromosome', 'translocation involving collagen A and platelet-derived growth factor', 'diffuse pattern between and among lipocytes']",
"noisy_text": " you can impress your friends and colleagues. You can say, this is DFSB. You don't need the storiform pattern. If you see this, you got the diagnosis. No other neoplasm really gets diffusely between and among lipocytes in a diffuse pattern like this, other than DFSB. Now you look up here and yeah, you do have the nice, beautiful storiform pattern here. And you don't really need a CD34 stain here. You can do it if you want to, if you like to sort of charge patients extra money, but this is a classic DFSB. And that ring chromosome, the collagen A, platelet-derived growth factor, the translocation is classic for that. And one",
"corrected_text": " you can impress your friends and colleagues. You can say, this is DFSP. You don't need the storiform pattern. If you see this, you got the diagnosis. No other neoplasm really gets diffusely between and among lipocytes in a diffuse pattern like this, other than DFSP. Now you look up here and yeah, you do have the nice, typical storiform pattern here. And you don't really need a CD34 stain here. You can do it if you want to, if you like to sort of charge patients extra money, but this is a classic DFSP. And that ring chromosome, the collagen A, platelet-derived growth factor, the translocation is classic for that. And one",
"med_umls_ids": "[[{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'diffuse', 'concept_id': 'C0205219', 'confidence': 1.0}, {'entity': 'lipocytes', 'concept_id': 'C0206131', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}], [{'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}, {'entity': 'storiform pattern', 'concept_id': 'C1336510', 'confidence': 0.8142904043197632}], [{'entity': 'CD34 stain', 'concept_id': 'C0038128', 'confidence': 0.5134490728378296}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'ring chromosome', 'concept_id': 'C0035639', 'confidence': 1.0}, {'entity': 'translocation', 'concept_id': 'C0040715', 'confidence': 1.0}, {'entity': 'collagen A', 'concept_id': 'C0009325', 'confidence': 0.9128584265708923}, {'entity': 'platelet-derived growth factor', 'concept_id': 'C0032200', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_329",
"caption_rating": "8"
},
{
"": "1005559",
"caption": "DFSP may not always have a typical storiform pattern.",
"image_path": "LlPaENuqzVQ_image_98c4a67e-3d00-4305-a909-bf584c2ec7a5.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['diffuse pattern between and among lipocytes', 'diffuse pattern between and among lipocytes', 'typical storiform pattern', 'ring chromosome', 'translocation involving collagen A and platelet-derived growth factor']",
"noisy_text": " you can impress your friends and colleagues. You can say, this is DFSB. You don't need the storiform pattern. If you see this, you got the diagnosis. No other neoplasm really gets diffusely between and among lipocytes in a diffuse pattern like this, other than DFSB. Now you look up here and yeah, you do have the nice, beautiful storiform pattern here. And you don't really need a CD34 stain here. You can do it if you want to, if you like to sort of charge patients extra money, but this is a classic DFSB. And that ring chromosome, the collagen A, platelet-derived growth factor, the translocation is classic for that. And one",
"corrected_text": " you can impress your friends and colleagues. You can say, this is DFSP. You don't need the storiform pattern. If you see this, you got the diagnosis. No other neoplasm really gets diffusely between and among lipocytes in a diffuse pattern like this, other than DFSP. Now you look up here and yeah, you do have the nice, typical storiform pattern here. And you don't really need a CD34 stain here. You can do it if you want to, if you like to sort of charge patients extra money, but this is a classic DFSP. And that ring chromosome, the collagen A, platelet-derived growth factor, the translocation is classic for that. And one",
"med_umls_ids": "[[{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'diffuse', 'concept_id': 'C0205219', 'confidence': 1.0}, {'entity': 'lipocytes', 'concept_id': 'C0206131', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}], [{'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}, {'entity': 'storiform pattern', 'concept_id': 'C1336510', 'confidence': 0.8142904043197632}], [{'entity': 'CD34 stain', 'concept_id': 'C0038128', 'confidence': 0.5134490728378296}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'ring chromosome', 'concept_id': 'C0035639', 'confidence': 1.0}, {'entity': 'translocation', 'concept_id': 'C0040715', 'confidence': 1.0}, {'entity': 'collagen A', 'concept_id': 'C0009325', 'confidence': 0.9128584265708923}, {'entity': 'platelet-derived growth factor', 'concept_id': 'C0032200', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_330",
"caption_rating": "8"
},
{
"": "1008999",
"caption": "The dermal infiltrate is composed entirely of lymphocytes, with a few extravasated erythrocytes in some areas, suggestive of pityriasis lichenoides.",
"image_path": "8S4LeiO6Bbk_image_8babc89a-e6f4-49c9-a23a-79c16fb030c5.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Infiltrate within the dermis composed entirely of lymphocytes.', 'Few extravasated erythrocytes in some areas.', 'Fragmented biopsy specimen with bluish stain.', 'Infiltrate within the dermis composed entirely of lymphocytes.', 'Few extravasated erythrocytes in some areas.']",
"noisy_text": " and if we look at the infiltrate within the dermis, we can see that it's composed entirely of lymphocytes. In some areas, there were a few extravasated erythrocytes, a few of which were carried up into the overlying epidermis. This constellation of findings is most suggestive of pittoriasis liganoides. Clinically, this patient had PLC, or pittoriasis liganoides chronica. I tend to view pittoriasis liganoides as running along a spectrum. A lot of times, we'll refer to the entire spectrum as Leuka Habermann disease, with pittoriasis liganoides chronica being on the one end of the spectrum, and pleva being on the other end of the spectrum, PLC being characterized by more scaly macules or scaly papules, and pleva being characterized by more crusted and eroded papulonecrotic type lesions. But the histology of the two conditions is actually quite similar. It's a matter of degree. With pleva, you're more likely the acute form of the condition to see more spongiosis, ballooning, necrosis, a denser infiltrate, more necrotics along the DEJ, pericaratosis containing neutrophils. With PLC, similar findings, just a little more blunt. The inflammatory infiltrate may be present around the superficial plexus only. One usually can see some pericaratosis, but there aren't as many necrotic keratinocytes along the DEJ, and a lot of times, the alterations within the epidermis are more subtle. But this was an example of biopsy from a patient with clinically documented pittoriasis like in wades clonica. Moving on to slide number 10. This was, I thought, a really cool case. This was a fragmented biopsy specimen, and you can see that the stain is quite bluish. I can't",
"corrected_text": " and if we look at the infiltrate within the dermis, we can see that it's composed entirely of lymphocytes. In some areas, there were a few extravasated erythrocytes, a few of which were carried up into the overlying epidermis. This constellation of findings is most suggestive of pityriasis lichenoides. Clinically, this patient had PLC, or pityriasis lichenoides chronica. I tend to view pityriasis lichenoides as running along a spectrum. A lot of times, we'refer to the entire spectrum as Leuka Habermann disease, with pityriasis lichenoides chronica being on the one end of the spectrum, and pleva being on the other end of the spectrum, PLC being characterized by more scaly macules or scaly papules, and pleva being characterized by more crusted and eroded papulonecrotic type lesions. But the histology of the two conditions is actually quite similar. It's a matter of degree. With pleva, you're more likely the acute form of the condition to see more spongiosis, ballooning, necrosis, a denser infiltrate, more necrotic along the DEJ, parakeratosis containing neutrophils. With PLC, similar findings, just a little more blunt. The inflammatory infiltrate may be present around the superficial plexus only. One usually can see some parakeratosis, but there aren't as many necrotic keratinocytes along the DEJ, and a lot of times, the alterations within the epidermis are more subtle. But this was an example of biopsy from a patient with clinically documented pittoriasis like in chronica. Moving on to slide number 10. This was, I thought, a really cool case. This was a fragmented biopsy specimen, and you can see that the stain is quite bluish. I can't",
"med_umls_ids": "[[{'entity': 'dermal infiltrate', 'concept_id': 'C0332448', 'confidence': 0.8524853587150574}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'extravasated', 'concept_id': 'C0015376', 'confidence': 0.868863582611084}, {'entity': 'erythrocytes', 'concept_id': 'C0014772', 'confidence': 1.0}, {'entity': 'areas', 'concept_id': 'C0205146', 'confidence': 1.0}, {'entity': 'pityriasis', 'concept_id': 'C0032024', 'confidence': 0.9999998807907104}, {'entity': 'lichenoides', 'concept_id': 'C0443248', 'confidence': 0.8475416302680969}], [{'entity': 'Pityriasis lichenoides', 'concept_id': 'C0162853', 'confidence': 1.0}, {'entity': 'running', 'concept_id': 'C0035953', 'confidence': 1.0}, {'entity': 'spectrum', 'concept_id': 'C1883073', 'confidence': 1.0}, {'entity': 'pityriasis lichenoides chronica', 'concept_id': 'C0162851', 'confidence': 1.0}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'scaly macules', 'concept_id': 'C0332573', 'confidence': 0.7616965174674988}, {'entity': 'papules', 'concept_id': 'C0332563', 'confidence': 0.9999999403953552}], [{'entity': 'histology', 'concept_id': 'C0019638', 'confidence': 1.0}, {'entity': 'pityriasis lichenoides', 'concept_id': 'C0162853', 'confidence': 1.0}, {'entity': 'pleva', 'concept_id': 'C0162852', 'confidence': 1.0}, {'entity': 'pleva', 'concept_id': 'C0162852', 'confidence': 1.0}, {'entity': 'acute', 'concept_id': 'C0205178', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'spongiosis', 'concept_id': 'C0702120', 'confidence': 1.0}, {'entity': 'ballooning', 'concept_id': 'C0004704', 'confidence': 1.0}, {'entity': 'necrosis', 'concept_id': 'C0027540', 'confidence': 1.0}], [{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'clinically documented', 'concept_id': 'C1828480', 'confidence': 0.814785361289978}, {'entity': 'pityriasis lichenoides chronica', 'concept_id': 'C0162851', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_331",
"caption_rating": "9"
},
{
"": "1007951",
"caption": "Presence of irregularly sized and shaped glands with variation in distribution indicating chronicity.",
"image_path": "r7OA0Trj5hQ_image_bbb3d6a9-2b31-40d8-ac87-c7c122f31da5.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Gastroesophageal junction with irregularly sized and shaped glands and variation in distribution.']",
"noisy_text": " metaplasia or dysplasia, either low-grade or high-grade. So this is a squamous epithelium. This is a gastric cardiac type of epithelium. So this is a gastroesophageal junction. Here you can see nice bifitting. And see the glands are not uniformly distributed. Variation in size. Some glands are small, some glands are large. And these glands are not branching normally, but you can see a nice bifitting. So these are all features of chronicity. Irregular size, shape, distribution means chronicity. Please remember, presence of lymphocytes and plasma cells is not a",
"corrected_text": " metaplasia or dysplasia, either low-grade or high-grade. So this is a squamous epithelium. This is a gastric cardiac type of epithelium. So this is a gastroesophageal junction. Here you can see nice bifitting. And see the glands are not uniformly distributed. Variation in size. Some glands are small, some glands are large. And these glands are not branching normally, but you can see a nice bifitting. So these are all features of chronicity. Irregular size, shape, distribution means chronicity. Please remember, presence of lymphocytes and plasma cells is not a",
"med_umls_ids": "[[{'entity': 'Identification', 'concept_id': 'C0020792', 'confidence': 1.0}, {'entity': 'squamous epithelium', 'concept_id': 'C0221909', 'confidence': 1.0}, {'entity': 'gastric cardiac type', 'concept_id': 'C0524600', 'confidence': 0.7429378628730774}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'gastroesophageal junction', 'concept_id': 'C0014871', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'irregularly', 'concept_id': 'C0425589', 'confidence': 0.905201256275177}, {'entity': 'sized', 'concept_id': 'C0600244', 'confidence': 0.8308623433113098}, {'entity': 'shaped glands', 'concept_id': 'C0332479', 'confidence': 0.7275685667991638}, {'entity': 'variation', 'concept_id': 'C0205419', 'confidence': 1.0}, {'entity': 'distribution', 'concept_id': 'C0037775', 'confidence': 1.0}, {'entity': 'chronicity', 'concept_id': 'C0547045', 'confidence': 1.0}], [{'entity': 'Importance', 'concept_id': 'C4086513', 'confidence': 0.96006178855896}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_332",
"caption_rating": "9"
},
{
"": "1006663",
"caption": "The presence of apoptotic bodies in a patient with IBD was unexpected.",
"image_path": "sDFjOtMAYrk_image_35239e77-655a-460b-b8bd-f010e24f88f8.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "[]",
"noisy_text": " it just didn't make sense for a patient with IBD to have this many just apoptotic micro abscesses. And I thought, well, maybe this is CMV, but I don't see the viral cytopathic changes. But lo and behold, the stain was positive. And then I went back. I went back and said, oh, yeah, there they are there. And there's a there's a more better one. Hold on. Right there, right there. And that's the one that actually lit up on the stain. Yeah, but really what took me off was the apoptosis. I didn't pick up on the on the viral cytopathic changes. Typically,",
"corrected_text": " it just didn't make sense for a patient with IBD to have this many just apoptotic bodies. And I thought, well, maybe this is CMV, but I don't see the viral cytopathic changes. But lo and behold, the stain was positive. And then I went back. I went back and said, oh, yeah, there they are there. And there's a there's a more better one. Hold on. Right there, right there. And that's the one that actually lit up on the stain. Yeah, but really what took me off was the apoptosis. I didn't pick up on the on the viral cytopathic changes. Typically,",
"med_umls_ids": "[[{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'apoptotic bodies', 'concept_id': 'C3269134', 'confidence': 1.0}, {'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'IBD', 'concept_id': 'C0021390', 'confidence': 1.0}], [{'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'CMV', 'concept_id': 'C0010823', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'cytomegalic cells', 'concept_id': 'C0391864', 'confidence': 0.864702582359314}], [{'entity': 'narrator', 'concept_id': 'C1135957', 'confidence': 0.7711340188980103}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'virus', 'concept_id': 'C0042776', 'confidence': 1.0}, {'entity': 'apoptosis', 'concept_id': 'C0162638', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_333",
"caption_rating": "7"
},
{
"": "1005095",
"caption": "Malignant peripheral nerve sheath tumor is rare in the skin",
"image_path": "jCw_NtnS6XU_image_b0439307-61c8-498f-993c-a7000aae3918.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " that's desmoplastic melanoma until proven otherwise, okay? So I think that's the main thing. And occasionally I get these where people will send them in and say they think it's a malignant peripheral nerve sheath tumor. I have a whole long video on my YouTube channel about that entity. You can check out if you want, but I'll just tell you this. I've only seen ever one malignant peripheral nerve sheath tumor in the skin. And it was a, even then, I only made that diagnosis with great trepidation because almost always",
"corrected_text": " that's desmoplastic melanoma until proven otherwise, okay? So I think that's the main thing. And occasionally I get these where people will send them in and say they think it's a malignant peripheral nerve sheath tumor. I have a whole long video on my YouTube channel about that entity. You can check out if you want, but I'll just tell you this. I've only seen ever one malignant peripheral nerve sheath tumor in the skin. And it was a, even then, I only made that diagnosis with great trepidation because almost always",
"med_umls_ids": "[[{'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'desmoplastic melanoma', 'concept_id': 'C1333280', 'confidence': 1.0}], [{'entity': 'Malignant peripheral nerve sheath', 'concept_id': 'C0278622', 'confidence': 0.9168763160705566}, {'entity': 'rare', 'concept_id': 'C0521114', 'confidence': 1.0}, {'entity': 'skin', 'concept_id': 'C0444099', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_334",
"caption_rating": "8"
},
{
"": "1008894",
"caption": "The background of the tissue sample shows very fine, delicate, thread-like collagen.",
"image_path": "QDb68_G1HR4_image_4097825f-1098-41ce-81f2-a72d488bacdf.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['fine delicate thread-like collagen', 'spindle cells', 'perineurioma', 'low-grade fibromyxoid sarcoma', 'whirled or swirled areas']",
"noisy_text": " look at that very fine delicate thread-like collagen in the background, the spindle cells are very thin and bland and sometimes if you depending on which way the cells are kind of sectioned, they can look a little more oval or even round and I think this is similar that's why this tumor one of the mimics that you can see one of the histologic mimics is perineurioma and I have another video about perineurioma that really goes into detail. Perineuriomas often have cells that look very much like this and both perineurioma as well as low-grade fibromyxoid sarcoma can have very whirled or swirled areas. This one's",
"corrected_text": " look at that very fine delicate thread-like collagen in the background, the spindle cells are very thin and bland and sometimes if you depending on which way the cells are kind of sectioned, they can look a little more oval or even round and I think this is similar that's why this tumor one of the mimics that you can see one of the histologic mimics is perineurioma and I have another video about perineurioma that really goes into detail. Perineuriomas often have cells that look very much like this and both perineurioma as well as low-grade fibromyxoid sarcoma can have very whirled or swirled areas. This one's",
"med_umls_ids": "[[{'entity': 'background', 'concept_id': 'C1706907', 'confidence': 1.0}, {'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'delicate', 'concept_id': 'C0241181', 'confidence': 0.7745490074157715}, {'entity': 'thread-like collagen', 'concept_id': 'C1979891', 'confidence': 0.845443606376648}], [{'entity': 'spindle cells', 'concept_id': 'C0682540', 'confidence': 1.0}, {'entity': 'thin', 'concept_id': 'C0205168', 'confidence': 1.0}, {'entity': 'bland', 'concept_id': 'C0227475', 'confidence': 0.7435316443443298}, {'entity': 'oval', 'concept_id': 'C1709367', 'confidence': 1.0}, {'entity': 'round', 'concept_id': 'C0332490', 'confidence': 1.0}, {'entity': 'angle of sectioning', 'concept_id': 'C0700320', 'confidence': 0.7131970524787903}], [{'entity': 'Perineurioma', 'concept_id': 'C0751691', 'confidence': 0.9999999403953552}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'histologic', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'mimics', 'concept_id': 'C0393040', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_335",
"caption_rating": "8"
},
{
"": "1004299",
"caption": "Cytologic atypia can be a helpful finding in cases of mild ischemia.",
"image_path": "sDFjOtMAYrk_image_6186fdd9-5438-4a29-9e87-049df53ff824.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['Superficial injury', 'Bottom crypts', 'Hyalinized lamina propria', 'Cytologic atypia', 'Superficial injury', 'Bottom crypts', 'Hyalinized lamina propria', 'Cytologic atypia']",
"noisy_text": " what you see in patients with ischemia. So basically, injury that's predominantly superficial with relative preservation of the bottom crypts. Very hyaluronized lamina propria when the ischemia has been ongoing for a while. It may or may not be there when the ischemia has been short-lived. Here you can see very nicely the superficial injury with relatively preserved bottoms. I find the cytologic atypia really helpful when I'm dealing with cases where I really don't know what's going on. I've caught maybe one or two cases of patients with subclinical very mild level ischemia that the only finding was just the cytologic atypia that I don't know where it's really coming from. And I'll show a case down the road. Actually, I'll show it right now. So this is a patient who I don't really remember the clinical history. I just thought, I mean, the architecture",
"corrected_text": " what you see in patients with ischemia. So basically, injury that's predominantly superficial with relative preservation of the bottom crypts. Very hyalinized lamina propria when the ischemia has been ongoing for a while. It may or may not be there when the ischemia has been short-lived. Here you can see very nicely the superficial injury with relatively preserved bottoms. I find the cytologic atypia really helpful when I'm dealing with cases where I really don't know what's going on. I've caught maybe one or two cases of patients with subclinical very mild level ischemia that the only finding was just the cytologic atypia that I don't know where it's really coming from. And I'll show a case down the road. Actually, I'll show it right now. So this is a patient who I don't really remember the clinical history. I just thought, I mean, the architecture",
"med_umls_ids": "[[{'entity': 'Superficial injury', 'concept_id': 'C0332671', 'confidence': 1.0}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}], [{'entity': 'Hyalinized lamina propria', 'concept_id': 'C0332230', 'confidence': 0.7577076554298401}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}], [{'entity': 'Cytologic atypia', 'concept_id': 'C0333865', 'confidence': 1.0}, {'entity': 'finding', 'concept_id': 'C0037088', 'confidence': 1.0}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'mild', 'concept_id': 'C1513302', 'confidence': 1.0}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_336",
"caption_rating": "8"
},
{
"": "1009267",
"caption": "DFSP may show loss of expression of CD34 and have a translocation between collagen 1a1 PDGF beta genes.",
"image_path": "QDb68_G1HR4_image_eb03e94f-15fe-4d21-915f-0ec33f6f6f98.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " more cellular and fibrosarcoma sometimes they lose expression of CD34 I'll make a video about DFSP at some point in the future that'll go over all this in detail so anyway you could do molecular testing there DFSP as a translocation between the collagen 1a1 PDGF beta genes and again here we have the fuss CREB 3L2 or 3L1 translocation so molecular testing could sort this out if you had trouble and of course MUC4 should be helpful too finally I'm going to show one last example and then I think you'll have seen nine different cases of low grade fibromyxoid",
"corrected_text": " more cellular and fibrosarcoma sometimes they loss of expression of CD34 I'll make a video about DFSP at some point in the future that'll go over all this in detail so anyway you could do molecular testing there DFSP as a translocation between the collagen 1a1 PDGF beta genes and again here we have the FUS-CREB3L2 or FUS-CREB3L1 so molecular testing could sort this out if you had trouble and of course MUC4 should be helpful too finally I'm going to show one last example and then I think you'll have seen nine different cases of low grade fibromyxoid",
"med_umls_ids": "[[{'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}, {'entity': 'loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'expression', 'concept_id': 'C0017262', 'confidence': 0.9999998807907104}, {'entity': 'CD34', 'concept_id': 'C0054953', 'confidence': 1.0}, {'entity': 'translocation', 'concept_id': 'C0040715', 'confidence': 1.0}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'beta genes', 'concept_id': 'C0242988', 'confidence': 0.8049559593200684}], [{'entity': 'Molecular testing', 'concept_id': 'C1521991', 'confidence': 0.8002516627311707}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}], [{'entity': 'MUC4', 'concept_id': 'C1417496', 'confidence': 0.9999999403953552}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_337",
"caption_rating": "8"
},
{
"": "1005778",
"caption": "Whirling pattern can be seen in perineurioma and dermatofibrosarcoma protuberans (DFSP).",
"image_path": "QDb68_G1HR4_image_eccb54ef-3bbb-47e2-b114-1e76f381358d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['whirling pattern']",
"noisy_text": " This one's not really showing that but some of them do, they have a lot of whirling pattern. So the two other things that keep in the differential here are perineurioma and also dermatofibrosarcoma protuberans, DFSP, which also has a tends to have a story form or whirled and swirled growth pattern and also has a translocation sarcoma, has very bland spindle cells. Okay, I guess I don't have any immunostains with me to show you today but just briefly the immunostains, most of the immunostains that we use for soft tissue tumors are negative most of the time in low-grade fibromyxoid sarcoma. CD34 is usually negative which is a pretty easy way to separate this from DFSP. The other thing is that low-grade fibromyxoid sarcoma usually is a relatively larger and deep, deep soft tissue below the fascia mass, although there are rare examples that are small and superficial and those seem to be more common in children. But DFSP is essentially always in the skin, the dermis or subcutaneous and rarely ever involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is",
"corrected_text": " This one's not really showing that but some of them do, they have a lot of whirling pattern. So the two other things that keep in the differential here are perineurioma and also dermatofibrosarcoma protuberans, DFSP, which also has a tends to have a story form or whirled and swirled growth pattern and also has a translocation sarcoma, has very bland spindle cells. Okay, I guess I don't have any immunostaining with me to show you today but just briefly the immunostaining, most of the immunostaining that we use for soft tissue tumors are negative most of the time in low-grade fibromyxoid sarcoma. CD34 is usually negative which is a pretty easy way to separate this from DFSP. The other thing is that low-grade fibromyxoid sarcoma usually is a relatively larger and deep, deep soft tissue below the fascia mass, although there are rare examples that are small and superficial and those seem to be more common in children. But DFSP is essentially always in the skin, the dermis or subcutaneous and rarely ever involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is",
"med_umls_ids": "[[{'entity': 'Whirling pattern', 'concept_id': 'C0449774', 'confidence': 0.6110570430755615}, {'entity': 'perineurioma', 'concept_id': 'C0751691', 'confidence': 0.9999999403953552}, {'entity': 'dermatofibrosarcoma protuberans', 'concept_id': 'C0206647', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}], [{'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}, {'entity': 'skin', 'concept_id': 'C0444099', 'confidence': 1.0}, {'entity': 'deep soft tissue', 'concept_id': 'C0225317', 'confidence': 0.7996832728385925}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_338",
"caption_rating": "8"
},
{
"": "1007548",
"caption": "Description of nuclear placement in xanthoma and signet ring cells. Diagnosis of gastric xanthoma and poorly differentiated signet cell carcinoma.",
"image_path": "r7OA0Trj5hQ_image_23235661-1c42-4ffa-bcbb-f55c9be57c00.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['centrally placed nucleus']",
"noisy_text": " most of the time centrally placed nucleus. Sometimes it is pushed to the periphery. The central nuclear placement is very important for a diagnosis of xanthoma. For a signet cells, it will be predominantly peripherally pushed nucleus. And when you have doubt, you do a CD68, which will be strongly positive. And so this is a gastric xanthoma. Here, it is more like a signet cells. And when you do cytokeratin, it will all be positive. So it's a poorly differentiated signet cell carcinoma. And there are only three types of pathologists in the world. And this, I got it again from Twitter, I think from",
"corrected_text": " most of the time centrally placed nucleus. Sometimes it is pushed to the periphery. The central nuclear placement is very important for a diagnosis of xanthoma. For a signet cells, it will be predominantly peripherally pushed nucleus. And when you have doubt, you do a CD68, which will be strongly positive. And so this is a gastric xanthoma. Here, it is more like a signet cells. And when you do cytokeratin, it will all be positive. So it's a poorly differentiated signet cell carcinoma. And there are only three types of pathologists in the world. And this, I got it again from Twitter, I think from",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'nuclear', 'concept_id': 'C0521447', 'confidence': 1.0}, {'entity': 'xanthoma', 'concept_id': 'C0302314', 'confidence': 1.0}, {'entity': 'signet ring cells', 'concept_id': 'C0333727', 'confidence': 1.0}, {'entity': 'Diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'gastric xanthoma', 'concept_id': 'C1282522', 'confidence': 1.0}, {'entity': 'poorly differentiated', 'concept_id': 'C0205617', 'confidence': 1.0}, {'entity': 'signet cell carcinoma', 'concept_id': 'C0206696', 'confidence': 0.9410539865493774}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_339",
"caption_rating": "8"
},
{
"": "1007705",
"caption": "Loss of cellular polarity is seen in the sample.",
"image_path": "r7OA0Trj5hQ_image_14db8a12-3821-44b4-9c8e-6a119b6dc825.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['nuclei touching the top of the apical membrane', 'prominent nuclei', 'loss of cellular polarity', 'cribriform', 'micropapillary process', 'nuclei touching the top of the apical membrane', 'prominent nuclei', 'loss of cellular polarity', 'cribriform', 'micropapillary process', 'nuclei touching the top of the apical membrane', 'prominent nuclei', 'loss of cellular polarity', 'cribriform', 'micropapillary process']",
"noisy_text": " Can you all see the nuclei touching the top of the apical membrane? And see the prominent nuclei. And see the nuclei are running in different directions. This nuclei is running in this direction, whereas this nuclei is running in this direction. This nuclei is running in this direction. So there is loss of polarity. Okay, so here also it is stratified, reaching up to the top, and it is showing loss of polarity. And see the cribriformic. And this is a micropapillary process. Since it's a high power, you are not able to appreciate it better. I will show it to you in the other pictures. But here",
"corrected_text": " Can you all see the nuclei touching the top of the apical membrane? And see the prominent nuclei. And see the nuclei are running in different directions. This nuclei is running in this direction, whereas this nuclei is running in this direction. This nuclei is running in this direction. So there is loss of cellular polarity. Okay, so here also it is stratified, reaching up to the top, and it is showing loss of cellular polarity. And see the cribriform. And this is a micropapillary process. Since it's a high power, you are not able to appreciate it better. I will show it to you in the other pictures. But here",
"med_umls_ids": "[[{'entity': 'Loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'cellular polarity', 'concept_id': 'C0085304', 'confidence': 1.0}, {'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}], [{'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'stratified', 'concept_id': 'C0205363', 'confidence': 1.0}, {'entity': 'cribriform', 'concept_id': 'C1621425', 'confidence': 0.9999999403953552}, {'entity': 'micropapillary process', 'concept_id': 'C1290608', 'confidence': 0.763504683971405}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_340",
"caption_rating": "8"
},
{
"": "1006208",
"caption": "The tumor is a clear cell carcinoma of the ovary, characterized by cytoplasmic clearing.",
"image_path": "3mRB9j0eyVM_image_f516f114-994a-4ab1-bef2-78a875e0b7ae.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gynecologic', 'Hematopathology', 'Soft tissue']",
"roi_text": "['papillary structures', 'transitional type cells', 'marked atypia', 'invasion in the ovarian stroma', 'cytoplasmic clearing', 'invasion in the ovarian stroma']",
"noisy_text": " tumor. Again here you can see the papillary structures that show stratification of the cells and the cells are of transitional type. So this is called Brenner borderline tumor because yet or still there is no invasion. When there is invasion of the cells here you can see there is marked ATPR in the urethelial cells or in the transitional cells and they show invasion in the ovarian stroma. Now it is named as malignant Brenner tumor or transitional cell carcinoma of the ovary. Here you can see this is the clear cell carcinoma of the ovary. You can well identify the cytoplasmic clearing these rounded clear structures cytoplasmic clearing of",
"corrected_text": " tumor. Again here you can see the papillary structures that show stratification of the cells and the cells are of transitional type. So this is called Brenner borderline tumor because yet or still there is no invasion. When there is invasion of the cells here you can see there is marked atypia in the urothelial cells or in the transitional cells and they show invasion in the ovarian stroma. Now it is named as malignant Brenner tumor or transitional cell carcinoma of the ovary. Here you can see this is the clear cell carcinoma of the ovary. You can well identify the cytoplasmic clearing these rounded clear structures cytoplasmic clearing of",
"med_umls_ids": "[[{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'Brenner borderline tumor', 'concept_id': 'C0334494', 'confidence': 0.9999999403953552}, {'entity': 'invasion', 'concept_id': 'C1269955', 'confidence': 1.0}], [{'entity': 'invasion', 'concept_id': 'C1269955', 'confidence': 1.0}, {'entity': 'malignant', 'concept_id': 'C0205282', 'confidence': 1.0}, {'entity': 'Brenner tumor', 'concept_id': 'C0006160', 'confidence': 1.0}, {'entity': 'transitional', 'concept_id': 'C1182674', 'confidence': 1.0}, {'entity': 'ovary', 'concept_id': 'C0029939', 'confidence': 1.0}], [{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'cell carcinoma', 'concept_id': 'C1518174', 'confidence': 1.0}, {'entity': 'ovary', 'concept_id': 'C0029939', 'confidence': 1.0}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'cytoplasmic clearing', 'concept_id': 'C0010834', 'confidence': 0.8013758659362793}]]",
"magnification": "2.0",
"height": "720.0",
"width": "960.0",
"id": "test_341",
"caption_rating": "8"
},
{
"": "1006580",
"caption": "The cells are bland and do not form cords or chains.",
"image_path": "pBR26SS0FX8_image_2e174b62-bb8a-44e9-910e-06ccc04325d6.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Hematopathology', 'Breast pathology']",
"roi_text": "['conventional myxoid liposarcoma', 'cells are spread apart', 'do not touch each other', 'large personal space bubble', 'good social distancing', 'cells are bland', 'do not form cords or chains', 'conventional myxoid liposarcoma', 'cells are spread apart', 'do not touch each other', 'large personal space bubble', 'good social distancing', 'cells are bland', 'do not form cords or chains']",
"noisy_text": " The one thing that I think is really helpful in telling it apart from a lot of other myxoid tumors is note that the cells are spread apart and do not touch each other. They like respect, they have good social distancing. Ooh, I just thought of that. Now I haven't thought of that since COVID started and that's a great thing. They have a very large personal space bubble, okay? And they're good social distancers. They stay away from their neighbors and usually very few of them overlap. They do not form cords and chains. So unlike some of the other myxoid stuff we talked about which have cords and chains and connected cells, you don't see connected cells usually in regular conventional myxoid liposarcoma. You see these little cells, they are also very bland. Again, a",
"corrected_text": " The one thing that I think is really helpful in telling it apart from a lot of other myxoid tumors is note that the cells are spread apart and do not touch each other. They like respect, they have good social distancing. Ooh, I just thought of that. Now I haven't thought of that since COVID started and that's a great thing. They have a very large personal space bubble, okay? And they're good social distancers. They stay away from their neighbors and usually very few of them overlap. They do not form cords and chains. So unlike some of the other myxoid stuff we talked about which have cords and chains and connected cells, you don't see connected cells usually in regular conventional myxoid liposarcoma. You see these little cells, they are also very bland. Again, a",
"med_umls_ids": "[[{'entity': 'myxoid liposarcoma', 'concept_id': 'C0206634', 'confidence': 1.0}, {'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'spread', 'concept_id': 'C0332261', 'confidence': 1.0}, {'entity': 'touch', 'concept_id': 'C0152054', 'confidence': 1.0}, {'entity': 'personal space', 'concept_id': 'C0031207', 'confidence': 0.9999998807907104}, {'entity': 'bubble', 'concept_id': 'C2347223', 'confidence': 0.8612070083618164}, {'entity': 'social distancing', 'concept_id': 'C0037412', 'confidence': 0.8001358509063721}], [{'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'bland', 'concept_id': 'C0227475', 'confidence': 0.7435316443443298}, {'entity': 'cords', 'concept_id': 'C0034869', 'confidence': 0.801885187625885}, {'entity': 'chains', 'concept_id': 'C0337112', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_342",
"caption_rating": "8"
},
{
"": "1007516",
"caption": "Thick stratum corneum and absence of hair follicles within the specimen.",
"image_path": "8S4LeiO6Bbk_image_68593f1e-960b-4c9e-b4dd-5dd53d2e6edf.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['dome-shaped papule']",
"noisy_text": " can be quite impressive. Moving on to slide number 6. With slide number 6 we've got a bisected shape biopsy specimen. Now one of the useful clues to the diagnosis in this case is recognizing that we've got a dome-shaped papule and that the biopsy is from an acral site. Notice that we've got a very very thick stratum corneum and a marked to virtual absence of hair follicles within the specimen. We do have kind of this fibrovascular core and of course in the center of the fibrovascular core here we've got several well-defined nerve fascicles and the spindled cells characterizing these nerve",
"corrected_text": " can be quite impressive. Moving on to slide number 6. With slide number 6 we've got a bisected shape biopsy specimen. Now one of the useful clues to the diagnosis in this case is recognizing that we've got a dome-shaped papule and that the biopsy is from an acral site. Notice that we've got a very very thick stratum corneum and a marked to virtual absence of hair follicles within the specimen. We do have kind of this fibrovascular core and of course in the center of the fibrovascular core here we've got several well-defined nerve fascicles and the spindled cells characterizing these nerve",
"med_umls_ids": "[[{'entity': 'Bisected', 'concept_id': 'C0589437', 'confidence': 0.7404435873031616}, {'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'dome-shaped papule', 'concept_id': 'C1711316', 'confidence': 0.752353847026825}, {'entity': 'acral site', 'concept_id': 'C0439746', 'confidence': 0.717435359954834}], [{'entity': 'stratum corneum', 'concept_id': 'C0221921', 'confidence': 1.0}, {'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'hair follicles', 'concept_id': 'C0221971', 'confidence': 0.9999998807907104}, {'entity': 'specimen', 'concept_id': 'C0370003', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'fibrovascular', 'concept_id': 'C0392759', 'confidence': 1.0}, {'entity': 'core', 'concept_id': 'C0444669', 'confidence': 0.9999999403953552}, {'entity': 'nerve fascicles', 'concept_id': 'C1185741', 'confidence': 0.8332967758178711}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_343",
"caption_rating": "8"
},
{
"": "1006766",
"caption": "Discussion of the unusual behavior of a tumor that looks benign but has a different behavior than other sarcomas, with a median time to metastasis of 15 years and cases reported up to 30 or 40 years after the original diagnosis.",
"image_path": "QDb68_G1HR4_image_353043e6-6c02-4d48-a642-e33dbc6b88d5.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['metastases to lung or pleura']",
"noisy_text": " If you follow patients much longer, the picture changes quite a bit and a significant subset, somewhere around 40 or even maybe even higher percent will eventually get metastases if you follow them over decades and that's what's so unusual about this tumor, not only does it look benign, it is a very, very different behavior than other sarcomas. Most high-grade sarcomas metastasize oftentimes within 5 years of diagnosis if they're going to metastasize. Now that's not always true, but oftentimes that's the case. This tumor is so different, I think the median time to metastasis in a large retrospective study by Harry Evans, I think that was published in American Journal of Surgical Pathology 2011, I'll put a link in the video description. If you follow them for many, many years, the average time, I think it was the median time actually to recurrence or to metastasis was 15 years, that's so strange, right, to have a tumor that waits 15 years to eventually spread or recur and that's not all. There are cases reported that are actually 30 or even 40 years out from the original diagnosis when a metastasis finally shows up. So unfortunately, that's a frustrating thing I think for both the treating physicians and the patients to know that basically you're never totally in the clear these things can recur or metastasize very, very long after diagnosis. When they metastasize, they often go to the lung or the pleura and there probably is some benefit at least",
"corrected_text": " If you follow patients much longer, the picture changes quite a bit and a significant subset, somewhere around 40 or even maybe even higher percent will eventually get metastases if you follow them over decades and that's what's so unusual about this tumor, not only does it look benign, it is a very, very different behavior than other sarcomas. Most high-grade sarcomas metastasize oftentimes within 5 years of diagnosis if they're going to metastasize. Now that's not always true, but oftentimes that's the case. This tumor is so different, I think the median time to metastasis in a large retrospective study by Harry Evans, I think that was published in American Journal of Surgical Pathology 2011, I'll put a link in the video description. If you follow them for many, many years, the average time, I think it was the median time actually to recurrence or to metastasis was 15 years, that's so strange, right, to have a tumor that waits 15 years to eventually spread or recur and that's not all. There are cases reported that are actually 30 or even 40 years out from the original diagnosis when a metastasis finally shows up. So unfortunately, that's a frustrating thing I think for both the treating physicians and the patients to know that basically you're never totally in the clear these things can recur or metastasize very, very long after diagnosis. When they metastasize, they often go to the lung or the pleura and there probably is some benefit at least",
"med_umls_ids": "[[{'entity': 'unusual', 'concept_id': 'C2700116', 'confidence': 1.0}, {'entity': 'behavior', 'concept_id': 'C0004927', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'benign', 'concept_id': 'C0205183', 'confidence': 1.0}, {'entity': 'behavior', 'concept_id': 'C0004927', 'confidence': 1.0}, {'entity': 'sarcomas', 'concept_id': 'C1261473', 'confidence': 1.0}, {'entity': 'median', 'concept_id': 'C0549183', 'confidence': 1.0}, {'entity': 'metastasis', 'concept_id': 'C0027627', 'confidence': 1.0}, {'entity': 'years', 'concept_id': 'C0439234', 'confidence': 1.0}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'years', 'concept_id': 'C0439234', 'confidence': 1.0}, {'entity': 'original', 'concept_id': 'C0205313', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'Metastases', 'concept_id': 'C0027627', 'confidence': 1.0}, {'entity': 'lung', 'concept_id': 'C0024109', 'confidence': 1.0}, {'entity': 'pleura', 'concept_id': 'C0032225', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_344",
"caption_rating": "7"
},
{
"": "1008783",
"caption": "Histopathological description of a punch biopsy specimen of a hemosiderotic variant of a dermatofibroma.",
"image_path": "8S4LeiO6Bbk_image_72ec0615-9379-4a20-b70d-60800c0a59e2.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Epidermis is hyperplastic and gently papillary']",
"noisy_text": " hemociderotic variant of a dermatofibroma. Moving on to slide number five. This was kind of a cool case. We have a bisected punch biopsy specimen here. If we move into higher power, we can see that the epidermis is hyperplastic and gently papillated. The quantified layer is altered somewhat. We got some compact ortho and probably a little bit of pericaratosis here are to tell at this power. The underlying dermis contains a patchy perivascular infiltrative lymphocytes and if we move to higher power, we can confirm these findings. Lymphocytes, dilated vessels, papillomatosis, and epidermal hyperplasia. There are discrete columns and mounds of pericaratosis within the",
"corrected_text": " hemociderotic variant of a dermatofibroma. Moving on to slide number five. This was kind of a cool case. We have a bisected punch biopsy specimen here. If we move into higher power, we can see that the epidermis is hyperplastic and gently papillated. The quantified layer is altered somewhat. We got some compact ortho and probably a little bit of parakeratosis here are to tell at this power. The underlying dermis contains a patchy perivascular infiltrative lymphocytes and if we move to higher power, we can confirm these findings. Lymphocytes, dilated vessels, papillomatosis, and epidermal hyperplasia. There are discrete columns and mounds of pericaratosis within the",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'punch biopsy', 'concept_id': 'C0182557', 'confidence': 1.0}, {'entity': 'hemosiderotic', 'concept_id': 'C0019114', 'confidence': 0.7758374810218811}, {'entity': 'variant', 'concept_id': 'C0205419', 'confidence': 1.0}, {'entity': 'dermatofibroma', 'concept_id': 'C0002991', 'confidence': 1.0}], [{'entity': 'Hyperplastic', 'concept_id': 'C0020507', 'confidence': 1.0}, {'entity': 'papillary epidermis', 'concept_id': 'C0682598', 'confidence': 0.8714284300804138}, {'entity': 'quantified', 'concept_id': 'C1709793', 'confidence': 0.6807526350021362}, {'entity': 'layer', 'concept_id': 'C0934502', 'confidence': 1.0}, {'entity': 'compact ortho', 'concept_id': 'C1333134', 'confidence': 0.7191344499588013}, {'entity': 'parakeratosis', 'concept_id': 'C0030436', 'confidence': 1.0}], [{'entity': 'Patchy', 'concept_id': 'C0205413', 'confidence': 1.0}, {'entity': 'perivascular', 'concept_id': 'C0442165', 'confidence': 1.0}, {'entity': 'infiltrative lymphocytes', 'concept_id': 'C0333386', 'confidence': 0.8475345373153687}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}], [{'entity': 'Discrete columns', 'concept_id': 'C0227428', 'confidence': 0.6879350543022156}, {'entity': 'mounds', 'concept_id': 'C2717795', 'confidence': 0.736616313457489}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_345",
"caption_rating": "8"
},
{
"": "1008781",
"caption": "Possible diagnosis of dermatofibrosarcoma protuberans (DFSP) based on the streaming of cells in the same direction and the presence of myxoid bland spindle cells.",
"image_path": "QDb68_G1HR4_image_7603fd9a-353a-483f-8a51-e8ef46508e9a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " here like that see all the cells are kind of streaming the same direction so one thing you could consider here I think would be would be a dermata fibrosarcoma protuberans a myxoid DFSP DFSPs particularly as they transform into a higher grade form they can begin to get kind of vesicular almost herringbone areas and even though this isn't nearly as cellular as a fibrosarcoma as DFSP I think still seeing myxoid bland spindle cell thing that has that has areas like this could really make me wonder am I dealing with a DFSP and DFSPs that get more cellular",
"corrected_text": " here like that see all the cells are kind of streaming the same direction so one thing you could consider here I think would be would be a dermatofibrosarcoma protuberans a myxoid DFSP DFSPs particularly as they transform into a higher grade form they can begin to get kind of vesicular almost herringbone areas and even though this isn't nearly as cellular as a fibrosarcoma as DFSP I think still seeing myxoid bland spindle cell thing that has that has areas like this could really make me wonder am I dealing with a DFSP and DFSPs that get more cellular",
"med_umls_ids": "[[{'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'dermatofibrosarcoma protuberans', 'concept_id': 'C0206647', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}, {'entity': 'streaming', 'concept_id': 'C0720356', 'confidence': 0.736393928527832}, {'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'direction', 'concept_id': 'C0449738', 'confidence': 1.0}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'myxoid bland spindle cells', 'concept_id': 'C0682540', 'confidence': 0.6821858286857605}], [{'entity': 'DFSPs', 'concept_id': 'C0334464', 'confidence': 0.8083938360214233}, {'entity': 'vesicular', 'concept_id': 'C0205378', 'confidence': 1.0}, {'entity': 'herringbone areas', 'concept_id': 'C0264075', 'confidence': 0.7204739451408386}, {'entity': 'transform', 'concept_id': 'C1510411', 'confidence': 0.8196498155593872}, {'entity': 'higher', 'concept_id': 'C0205250', 'confidence': 1.0}, {'entity': 'grade form', 'concept_id': 'C0441800', 'confidence': 0.7383699417114258}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_346",
"caption_rating": "8"
},
{
"": "1005319",
"caption": "Nevus sebaceus hamartoma involves both the epithelial and follicular elements, as well as the perifollicular connective tissue.",
"image_path": "LlPaENuqzVQ_image_e41eadb4-ec94-4b64-af23-4f0f02dfac1a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['nevus sebaceus hamartoma', 'epithelial and follicular elements', 'perifollicular connective tissue', 'dense fibrous stroma', 'basal cell carcinoma', 'clefting', 'nevus sebaceus hamartoma', 'epithelial and follicular elements', 'perifollicular connective tissue', 'dense fibrous stroma', 'basal cell carcinoma', 'clefting']",
"noisy_text": " because it grows back, because there's also a soil component in addition to the growth on top of the soil. You've got to have the background stroma, which is part of the nevus sebaceus hammertoma as well. So this is a similar kind of deal. It's a neoplasm involving both the epithelial and the follicular elements, as well as the perifollicular connective tissue. And it's kind of got this pretty characteristic, it's kind of a relatively dense fibrous stroma. It's not loose and mixoid like the stroma you see around the basal cell carcinoma. Notice that there's no clefting between this, like we see with the basal cell carcinoma. So this",
"corrected_text": " because it grows back, because there's also a soil component in addition to the growth on top of the soil. You've got to have the background stroma, which is part of the nevus sebaceus hammertoma as well. So this is a similar kind of deal. It's a neoplasm involving both the epithelial and the follicular elements, as well as the perifollicular connective tissue. And it's kind of got this pretty characteristic, it's kind of a relatively dense fibrous stroma. It's not loose and mixoid like the stroma you see around the basal cell carcinoma. Notice that there's no clefting between this, like we see with the basal cell carcinoma. So this",
"med_umls_ids": "[[{'entity': 'Nevus sebaceus hamartoma', 'concept_id': 'C4476818', 'confidence': 0.8189855217933655}, {'entity': 'epithelial', 'concept_id': 'C0221908', 'confidence': 1.0}, {'entity': 'follicular', 'concept_id': 'C0439682', 'confidence': 1.0}, {'entity': 'elements', 'concept_id': 'C0013879', 'confidence': 1.0}, {'entity': 'perifollicular', 'concept_id': 'C1704236', 'confidence': 0.805053174495697}, {'entity': 'connective tissue', 'concept_id': 'C0009780', 'confidence': 1.0}], [{'entity': 'neoplasm', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}, {'entity': 'loose', 'concept_id': 'C0205407', 'confidence': 1.0}, {'entity': 'mixoid', 'concept_id': 'C3850557', 'confidence': 0.7173998355865479}, {'entity': 'stroma', 'concept_id': 'C0927195', 'confidence': 1.0}, {'entity': 'basal cell carcinoma', 'concept_id': 'C0007117', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_347",
"caption_rating": "9"
},
{
"": "1005468",
"caption": "Intraductal carcinoma of the prostate is usually due to invasion, colonization by adjacent invasive tumor.",
"image_path": "iklRyY1nBIE_image_943dc3a5-3548-4b93-8b05-23755f6f6e2c.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['basal cells at the periphery', 'enlarged nuclei', 'intraductal carcinoma of the prostate', 'adjacent invasive tumor', 'previously benign gland', 'basal cells at the periphery', 'enlarged nuclei', 'intraductal carcinoma of the prostate', 'adjacent invasive tumor', 'previously benign gland']",
"noisy_text": " Let me show you what the cocktail looks like. Again, this is the pin three, or some call it pin four. You have the P63, you have the hemoglobin cytokeratin, and then you have the racemase, which is the pink chromogen. And as you can see, as I demonstrated on the H&E, basal cells are indeed present. This is too much for high-grade pin. This is basically what is called a solid cribriform kind of pattern, in which over 50% of the lumen is filled by tumor cells. So this is way too much for high-grade pin. But it's not invasive, because you have basal cells at the periphery. And the nuclei are enlarged. These nuclei are about six times the size of normal prostate nuclei. So this case meets the criteria for introductal carcinoma of the prostate. There is an invasive component, which you can see is negative for basal cell markers. But you have the introductal component. And this is a very interesting entity. The vast majority of cases, and I'll show you the corresponding radical prostatectomy specimens in a second, but the vast majority of these so-called introductal carcinoma of the prostate is due to invasion, colonization by adjacent invasive tumor. And it usually occurs in patients that have high-volume tumors. When I show you the corresponding radical prostatectomies, you'll see what I'm talking about. You usually don't have this in patients in their radicals that have 5% prostate cancer or 10% prostate cancer. It's usually patients that have extensive prostate cancer involvement, and the invasive glands basically have nowhere else to go but to colonize adjacent benign glands. And I'll demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues,",
"corrected_text": " Let me show you what the cocktail looks like. Again, this is the pin three, or some call it pin four. You have the P63, you have the hemoglobin cytokeratin, and then you have the racemase, which is the AMACR. And as you can see, as I demonstrated on the H&E, basal cells are indeed present. This is too much for high-grade pin. This is basically what is called a solid cribriform kind of pattern, in which over 50% of the lumen is filled by tumor cells. So this is way too much for high-grade pin. But it's not invasive, because you have basal cells at the periphery. And the nuclei are enlarged. These nuclei are about six times the size of normal prostate nuclei. So this case meets the criteria for intraductal carcinoma of the prostate. There is an invasive component, which you can see is negative for basal cell markers. But you have the intraductal component. And this is a very interesting entity. The vast majority of cases, and I'll show you the corresponding radical prostatectomy specimens in a second, but the vast majority of these so-called intraductal carcinoma of the prostate is due to invasion, colonization by adjacent invasive tumor. And it usually occurs in patients that have high-volume tumors. When I show you the corresponding radical prostatectomies, you'll see what I'm talking about. You usually don't have this in patients in their radicals that have 5% prostate cancer or 10% prostate cancer. It's usually patients that have extensive prostate cancer involvement, and the invasive glands basically have nowhere else to go but to colonize adjacent benign glands. And I'demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues,",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'cocktail', 'concept_id': 'C0678420', 'confidence': 1.0}, {'entity': 'markers', 'concept_id': 'C0181734', 'confidence': 0.890313982963562}, {'entity': 'intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate diagnosis', 'concept_id': 'C0011900', 'confidence': 0.7927443981170654}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'basal cells', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}], [{'entity': 'Enlarged nuclei', 'concept_id': 'C4013177', 'confidence': 0.7774685621261597}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'normal', 'concept_id': 'C0205307', 'confidence': 1.0}], [{'entity': 'Intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'invasion', 'concept_id': 'C1269955', 'confidence': 1.0}, {'entity': 'colonization', 'concept_id': 'C4289767', 'confidence': 1.0}, {'entity': 'adjacent', 'concept_id': 'C0205117', 'confidence': 1.0}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}], [{'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'benign gland', 'concept_id': 'C0205183', 'confidence': 0.7986565828323364}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_348",
"caption_rating": "7"
},
{
"": "1004297",
"caption": "Superficial injury with relatively preserved bottom crypts is indicative of ischemia.",
"image_path": "sDFjOtMAYrk_image_6186fdd9-5438-4a29-9e87-049df53ff824.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['Superficial injury', 'Bottom crypts', 'Hyalinized lamina propria', 'Cytologic atypia', 'Superficial injury', 'Bottom crypts', 'Hyalinized lamina propria', 'Cytologic atypia']",
"noisy_text": " what you see in patients with ischemia. So basically, injury that's predominantly superficial with relative preservation of the bottom crypts. Very hyaluronized lamina propria when the ischemia has been ongoing for a while. It may or may not be there when the ischemia has been short-lived. Here you can see very nicely the superficial injury with relatively preserved bottoms. I find the cytologic atypia really helpful when I'm dealing with cases where I really don't know what's going on. I've caught maybe one or two cases of patients with subclinical very mild level ischemia that the only finding was just the cytologic atypia that I don't know where it's really coming from. And I'll show a case down the road. Actually, I'll show it right now. So this is a patient who I don't really remember the clinical history. I just thought, I mean, the architecture",
"corrected_text": " what you see in patients with ischemia. So basically, injury that's predominantly superficial with relative preservation of the bottom crypts. Very hyalinized lamina propria when the ischemia has been ongoing for a while. It may or may not be there when the ischemia has been short-lived. Here you can see very nicely the superficial injury with relatively preserved bottoms. I find the cytologic atypia really helpful when I'm dealing with cases where I really don't know what's going on. I've caught maybe one or two cases of patients with subclinical very mild level ischemia that the only finding was just the cytologic atypia that I don't know where it's really coming from. And I'll show a case down the road. Actually, I'll show it right now. So this is a patient who I don't really remember the clinical history. I just thought, I mean, the architecture",
"med_umls_ids": "[[{'entity': 'Superficial injury', 'concept_id': 'C0332671', 'confidence': 1.0}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}], [{'entity': 'Hyalinized lamina propria', 'concept_id': 'C0332230', 'confidence': 0.7577076554298401}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}], [{'entity': 'Cytologic atypia', 'concept_id': 'C0333865', 'confidence': 1.0}, {'entity': 'finding', 'concept_id': 'C0037088', 'confidence': 1.0}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'mild', 'concept_id': 'C1513302', 'confidence': 1.0}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_349",
"caption_rating": "8"
},
{
"": "1005691",
"caption": "Pseudomembranes can be caused by Clostridioides difficile colitis or ischemic injury.",
"image_path": "sDFjOtMAYrk_image_b3d68748-0a10-4972-9581-5d3a1b3c9021.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['lamina propria', 'pseudomembranes', 'ischemia', 'C. diff']",
"noisy_text": " will give you pseudomembranes. Ischemic injury can also give it to you. And the one thing to note is that, so this patient had C. difficile colitis by laboratory, but he was not responding to treatment and they just decided to take a biopsy. And you can see here that in the lamina propria is not hyalinized. Now, does that mean that ischemia is excluded? No, because if it's, you know, it depends on the clinical history. If it's recent ischemia that happened within, I don't know, 24, 48 hours, you know, the hyalinopropia may not have had time to hyalinize. How long does it take for the lamina propria to become pink? I don't know, but longer. So C. diff. Oh, another mimic of ischemia. And you can see why this mimics ischemia. The lamina propria is kind of pink and hyalinized. On top of that, there's actually some architectural distortion. This",
"corrected_text": " will give you pseudomembranes. Ischemic injury can also give it to you. And the one thing to note is that, so this patient had Clostridioides difficile colitis by laboratory, but he was not responding to treatment and they just decided to take a biopsy. And you can see here that in the lamina propria is not hyalinized. Now, does that mean that ischemia is excluded? No, because if it's, you know, it depends on the clinical history. If it's recent ischemia that happened within, I don't know, 24, 48 hours, you know, the hyalinopropia may not have had time to hyalinize. How long does it take for the lamina propria to become pink? I don't know, but longer. So C. diff. Oh, another mimic of ischemia. And you can see why this mimics ischemia. The lamina propria is kind of pink and hyalinized. On top of that, there's actually some architectural distortion. This",
"med_umls_ids": "[[{'entity': 'Pseudomembranes', 'concept_id': 'C0240821', 'confidence': 1.0}, {'entity': 'Clostridioides', 'concept_id': 'C4406271', 'confidence': 1.0}, {'entity': 'colitis', 'concept_id': 'C0009319', 'confidence': 1.0}, {'entity': 'ischemic injury', 'concept_id': 'C2945681', 'confidence': 0.8915668725967407}], [{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'hyalinized', 'concept_id': 'C0332230', 'confidence': 1.0}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}, {'entity': 'excluded', 'concept_id': 'C0332196', 'confidence': 1.0}], [{'entity': 'C. diff', 'concept_id': 'C0238106', 'confidence': 0.8398770093917847}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}, {'entity': 'pink', 'concept_id': 'C0332585', 'confidence': 1.0}, {'entity': 'hyalinized lamina propria', 'concept_id': 'C0332230', 'confidence': 0.7577076554298401}, {'entity': 'architectural changes', 'concept_id': 'C0003737', 'confidence': 0.7067119479179382}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_350",
"caption_rating": "8"
},
{
"": "1008836",
"caption": "The diagnosis is a desmoplastic tricholemmomaphthelioma, which has a different morphology and stroma than a MAC.",
"image_path": "LlPaENuqzVQ_image_d6f934fb-48d8-4b6f-8c4c-98bcf5d2070e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['desmoplastic tricholemmomaphthelioma', 'calcification', 'perineural invasion', 'cleft between the stroma and the epithelium', 'calcification', 'cleft between the stroma and the epithelium']",
"noisy_text": " There may be some little small duct-like structures at the top of the calcification. This is a desmoplastic trichophthelioma. It's different than a MAC. So it's got a different morphology. It's got the calcification and different stroma. These do not get neurotropic involvement. So, and you know, this is a definitive diagnosis here also. We don't need to stain this or anything. We would diagnose this as a desmoplastic MAC or a microcystic or a desmoplastic tricho and then just move on to the next case. It's different than MAC. It's different than basal cell. It doesn't have the clest between the stroma and the epithelium here. Okay, so",
"corrected_text": " There may be some little small duct-like structures at the top of the calcification. This is a desmoplastic trichoepithelioma. It's different than a MAC. So it's got a different morphology. It's got the calcification and different stroma. These do not get neurotropic involvement. So, and you know, this is a definitive diagnosis here also. We don't need to stain this or anything. We would diagnose this as a desmoplastic MAC or a microcystic or a desmoplastic tricho and then just move on to the next case. It's different than MAC. It's different than basal cell. It doesn't have the cleft between the stroma and the epithelium here. Okay, so",
"med_umls_ids": "[[{'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'desmoplastic tricholemmomaphthelioma', 'concept_id': 'C1275206', 'confidence': 0.8335589170455933}, {'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}, {'entity': 'stroma', 'concept_id': 'C0927195', 'confidence': 1.0}, {'entity': 'MAC', 'concept_id': 'C0009545', 'confidence': 0.9999999403953552}], [{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'perineural invasion', 'concept_id': 'C1317608', 'confidence': 1.0}], [{'entity': 'duct-like structures', 'concept_id': 'C1880423', 'confidence': 0.9012507796287537}, {'entity': 'calcification', 'concept_id': 'C0006660', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_351",
"caption_rating": "7"
},
{
"": "1004408",
"caption": "Some of the vascular spaces contain extravasated erythrocytes.",
"image_path": "8S4LeiO6Bbk_image_fa7fc227-da4a-4abd-aa17-71ba0970edd7.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Upper portions of the biopsy specimen', 'Dermis with clear spaces', 'Central portion of the lesion with dilated vascular spaces and papillary projections', 'Plump endothelial cells lining the vascular spaces', 'Extravasated erythrocytes present within the stroma', 'Upper portions of the biopsy specimen', 'Dermis with clear spaces', 'Central portion of the lesion with dilated vascular spaces and papillary projections', 'Plump endothelial cells lining the vascular spaces', 'Extravasated erythrocytes present within the stroma']",
"noisy_text": " pencil on that all clear. That is kind of confined to the upper portions of the biopsy specimen, so the action appears to be here with the dermis. The epidermis may be mildly hyperplastic, but you can see we've got these clear spaces present throughout the dermis. And if we move to higher power, we can see that in the central portion of the lesion, we've got a collection of vascular spaces that are quite large or dilated. Many of these are lined by very plump kind of epithelioid or hobnailed endothelial cells, and some of them contain papillary projections that extend into the limina. If you look around, you can see these papillary projections. There are a few extravasated erythrocytes present within the stroma. So clearly, we've got this vascular neoplasma here",
"corrected_text": " pencil on that all clear. That is kind of confined to the upper portions of the biopsy specimen, so the action appears to be here with the dermis. The epidermis may be mildly hyperplastic, but you can see we've got these clear spaces present throughout the dermis. And if we move to higher power, we can see that in the central portion of the lesion, we've got a collection of vascular spaces that are quite large or dilated. Many of these are lined by very plump kind of epithelioid or hobnailed endothelial cells, and some of them contain papillary projections that extend into the limina. If you look around, you can see these papillary projections. There are a few extravasated erythrocytes present within the stroma. So clearly, we've got this vascular neoplasma here",
"med_umls_ids": "[[{'entity': 'biopsy specimen', 'concept_id': 'C0677862', 'confidence': 1.0}, {'entity': 'spaces', 'concept_id': 'C1883067', 'confidence': 0.7782474160194397}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'collection', 'concept_id': 'C0600644', 'confidence': 1.0}, {'entity': 'dilated', 'concept_id': 'C0700124', 'confidence': 0.9999999403953552}, {'entity': 'vascular spaces', 'concept_id': 'C0225983', 'confidence': 0.819495439529419}, {'entity': 'plump endothelial cells', 'concept_id': 'C0225336', 'confidence': 0.80415940284729}, {'entity': 'papillary projections', 'concept_id': 'C0016538', 'confidence': 0.7451471090316772}], [{'entity': 'vascular', 'concept_id': 'C0005847', 'confidence': 0.9999998807907104}, {'entity': 'extravasated', 'concept_id': 'C0015376', 'confidence': 0.868863582611084}, {'entity': 'erythrocytes', 'concept_id': 'C0014772', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "758.0",
"width": "1920.0",
"id": "test_352",
"caption_rating": "8"
},
{
"": "1005593",
"caption": "Granulomas can be caused by tuberculosis, sarcoidosis, fungal infections, idiopathic or foreign bodies.",
"image_path": "r7OA0Trj5hQ_image_d05bd62a-a5d2-47ab-841d-e48268e56522.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Granulomas in the lamina propria', 'Granulomas in the lamina propria', 'Lymphoid follicles in the stomach', 'Cytoplasmic inclusions', 'Granulomas in the lamina propria', 'Lymphoid follicles in the stomach', 'Cytoplasmic inclusions', 'Granulomas in the lamina propria', 'Lymphoid follicles in the stomach', 'Cytoplasmic inclusions']",
"noisy_text": " So this is chronic colitis with activity. These are granulomas in the lamina propria. Think of tuberculosis in India, sarcoidosis, fungal infections, or idiopathic, or foreign bodies. So those are all the four main things. Any granuloma, infectious or non-infectious. When infectious, is it necrotizing or non-necrotizing? Lymphoid follicles, again, abnormal in the stomach. And they are seen in the lamina propria, chronic gastroenteritis. You can all identify these beautiful inclusions. And some cytoplasmic inclusions also, nuclear and",
"corrected_text": " So this is chronic colitis with activity. These are granulomas in the lamina propria. Think of tuberculosis in India, sarcoidosis, fungal infections, or idiopathic, or foreign bodies. So those are all the four main things. Any granuloma, infectious or non-infectious. When infectious, is it necrotizing or non-necrotizing? Lymphoid follicles, again, abnormal in the stomach. And they are seen in the lamina propria, chronic gastroenteritis. You can all identify these beautiful inclusions. And some cytoplasmic inclusions also, nuclear and",
"med_umls_ids": "[[{'entity': 'Chronic colitis', 'concept_id': 'C0267375', 'confidence': 0.9999999403953552}, {'entity': 'activity', 'concept_id': 'C0026606', 'confidence': 1.0}, {'entity': 'granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}], [{'entity': 'Granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}, {'entity': 'tuberculosis', 'concept_id': 'C0041296', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'fungal infections', 'concept_id': 'C0026946', 'confidence': 1.0}, {'entity': 'idiopathic', 'concept_id': 'C0332240', 'confidence': 0.9999998807907104}, {'entity': 'foreign bodies', 'concept_id': 'C0016542', 'confidence': 1.0}], [{'entity': 'Lymphoid follicles', 'concept_id': 'C0229654', 'confidence': 0.9380706548690796}, {'entity': 'abnormal', 'concept_id': 'C0205161', 'confidence': 1.0}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'chronic gastroenteritis', 'concept_id': 'C0017160', 'confidence': 0.8353270292282104}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_353",
"caption_rating": "8"
},
{
"": "1004640",
"caption": "Mycophenol-associated injury shows a lot more eosinophils than GVHD patients, typically more than 15 per high power field.",
"image_path": "sDFjOtMAYrk_image_4505e5f8-8d5f-4ace-9e27-e50990dd4a27.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "[]",
"noisy_text": " with microphenol-associated injury have many more in the way of eosinophils, a lot more in the way of eosinophils than GVHD patients do. So that's really, really helpful. Is there a number? I think it's more than 15 per high power field. Typically, I just say, you know, the presence of eosinophils or prominent eosinophils favors microphenol. The other thing is you don't see any neuroendocrine cell aggregates. Those you see in GVHD. The other thing is you don't see apoptotic micro abscesses. Those will be in GVHD and you will not see them in microphenol. And then, you know, actually, the main finding, let's talk about the main finding, which is what? Yeah, exactly.",
"corrected_text": " with microphenol-associated injury have many more in the way of eosinophils, a lot more in the way of eosinophils than GVHD patients do. So that's really, really helpful. Is there a number? I think it's more than 15 per high power field. Typically, I just say, you know, the presence of eosinophils or prominent eosinophils favors microphenol. The other thing is you don't see any neuroendocrine cell aggregates. Those you see in GVHD. The other thing is you don't see apoptotic micro abscesses. Those will be in GVHD and you will not see them in microphenol. And then, you know, actually, the main finding, let's talk about the main finding, which is what? Yeah, exactly.",
"med_umls_ids": "[[{'entity': 'Mycophenol-associated injury', 'concept_id': 'C0552509', 'confidence': 0.6023857593536377}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'GVHD', 'concept_id': 'C0018133', 'confidence': 1.0}, {'entity': 'patients', 'concept_id': 'C0030705', 'confidence': 1.0}], [{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'mycophenol', 'concept_id': 'C0883242', 'confidence': 0.8315404653549194}], [{'entity': 'Neuroendocrine cell', 'concept_id': 'C1518275', 'confidence': 1.0}, {'entity': 'aggregates', 'concept_id': 'C0205418', 'confidence': 1.0}, {'entity': 'apoptotic bodies', 'concept_id': 'C3269134', 'confidence': 1.0}, {'entity': 'mycophenol-associated injury', 'concept_id': 'C0552509', 'confidence': 0.6023857593536377}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_354",
"caption_rating": "8"
},
{
"": "1007798",
"caption": "The hamartoma involves both the epithelial component and a fibrous sheath around the hair follicle.",
"image_path": "LlPaENuqzVQ_image_40616c81-7aed-4be5-9936-764c914b067e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['miniaturized hair follicle', 'mantle zone', 'stem cell area', 'bulge', 'apocrine gland', 'sebaceous gland', 'hamartoma', 'fibrous sheath']",
"noisy_text": " Like, it looks more like if there's, if I'm going to guess, like there's, I feel like there's a little bit of like, I would guess more like towards the, like a glandular. Yeah, well, it's, it's, it's a little miniaturized hair follicle. Nope. It's like this little guy here. It's like a little tiny follicle. And there's, we always think of three parts of the hair follicle. We think of the infundibulum, the isthmus, and we think of the inferior portion, but there's a very important part right around the isthmic part, just beneath the follicle, the infundibulum, and then where the inferior portion begins, that's known as the mantle zone. And that's kind of where all the action is. That's really kind of a stem cell area that sometimes those cells will form a little bulge there and they actually will end up forming an apocrine gland. Sometimes they'll end up forming a sebaceous gland. Sometimes they, you know, will just, they'll form, sometimes they form a little hammertoma, like you see right here. And they actually end up getting you this little sort of primitive little, it almost looks like a mini hair follicle that didn't really form. And then when you look at a hair follicle, it's comprised not only of the epithelial component, but there's also a periepithelial sheath around it, a fibrous sheath around the hair follicle. And so this is a hammertoma that involves both of those. So it's got a fibrous element to it. And then",
"corrected_text": " Like, it looks more like if there's, if I'm going to guess, like there's, I feel like there's a little bit of like, I would guess more like towards the, like a glandular. Yeah, well, it's, it's, it's a little miniaturized hair follicle. Nope. It's like this little guy here. It's like a little tiny follicle. And there's, we always think of three parts of the hair follicle. We think of the infundibulum, the isthmus, and we think of the inferior portion, but there's a very important part right around the isthmic part, just beneath the follicle, the infundibulum, and then where the inferior portion begins, that's known as the mantle zone. And that's kind of where all the action is. That's really kind of a stem cell area that sometimes those cells wiform a little bulge there and they actually wiend up forming an apocrine gland. Sometimes they'end up forming a sebaceous gland. Sometimes they, you know, will just, they'form, sometimes they form a little hamartoma, like you see right here. And they actually end up getting you this little sort of primitive little, it almost looks like a mini hair follicle that didn't really form. And then when you look at a hair follicle, it's comprised not only of the epithelial component, but there's also a periepithelial sheath around it, a fibrous sheath around the hair follicle. And so this is a hamartoma that involves both of those. So it's got a fibrous element to it. And then",
"med_umls_ids": "[[{'entity': 'narrator', 'concept_id': 'C1135957', 'confidence': 0.7711340188980103}, {'entity': 'miniaturized', 'concept_id': 'C0872350', 'confidence': 0.8111259341239929}, {'entity': 'hair follicle', 'concept_id': 'C0221971', 'confidence': 1.0}, {'entity': 'stem cell', 'concept_id': 'C0038250', 'confidence': 1.0}, {'entity': 'mantle zone', 'concept_id': 'C1512987', 'confidence': 1.0}], [{'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'mantle', 'concept_id': 'C0232445', 'confidence': 0.8497024178504944}, {'entity': 'zone', 'concept_id': 'C1710706', 'confidence': 1.0}, {'entity': 'bulge', 'concept_id': 'C0038999', 'confidence': 0.9999999403953552}, {'entity': 'apocrine gland', 'concept_id': 'C0003584', 'confidence': 0.9999998807907104}, {'entity': 'sebaceous gland', 'concept_id': 'C0036505', 'confidence': 1.0}, {'entity': 'hamartoma', 'concept_id': 'C0018552', 'confidence': 0.9999999403953552}], [{'entity': 'hamartoma', 'concept_id': 'C0018552', 'confidence': 0.9999999403953552}, {'entity': 'epithelial component', 'concept_id': 'C1707933', 'confidence': 0.8783122897148132}, {'entity': 'fibrous sheath', 'concept_id': 'C1185724', 'confidence': 1.0}, {'entity': 'hair follicle', 'concept_id': 'C0221971', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_355",
"caption_rating": "9"
},
{
"": "1004449",
"caption": "No involvement of the epidermis is seen.",
"image_path": "udoW6VSqsm4_image_59d0e5dd-f50c-497c-afb3-e8743731f6f9.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " Okay, so here we have a punch biopsy, non-equal skin. What we can see is there is a more sparse, moderate, and full trait in the superficial and deep dermis, and into the fat as well. And there's some eosinophilic component to it as well. Okay, what's the overall pattern? It's probably a superficial and deep, almost like a little funiculitis. It does go into the fat, and perivascular and interstitial. Yeah, and interstitial. And notice that there's no epidermal involved. No, epidermis is completely sparse. Even higher magnification. Now what do you see? Now I",
"corrected_text": " Okay, so here we have a punch biopsy, non-equal skin. What we can see is there is a more sparse, moderate, and full trait in the superficial and deep dermis, and into the fat as well. And there's some eosinophilic component to it as well. Okay, what's the overall pattern? It's probably a superficial and deep, almost like a little funiculitis. It does go into the fat, and perivascular and interstitial. Yeah, and interstitial. And notice that there's no epidermal involved. No, epidermis is completely sparse. Even higher magnification. Now what do you see? Now I",
"med_umls_ids": "[[{'entity': 'Punch biopsy', 'concept_id': 'C0182557', 'confidence': 1.0}, {'entity': 'normal skin', 'concept_id': 'C0558145', 'confidence': 1.0}, {'entity': 'moderate', 'concept_id': 'C0205081', 'confidence': 1.0}, {'entity': 'trait', 'concept_id': 'C0599883', 'confidence': 1.0}, {'entity': 'superficial', 'concept_id': 'C0205124', 'confidence': 1.0}, {'entity': 'deep dermis', 'concept_id': 'C0205125', 'confidence': 0.7651135921478271}, {'entity': 'fat', 'concept_id': 'C0015677', 'confidence': 1.0}], [{'entity': 'eosinophilic', 'concept_id': 'C0333930', 'confidence': 1.0}, {'entity': 'component', 'concept_id': 'C0449432', 'confidence': 1.0}, {'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}], [{'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}, {'entity': 'consistent with', 'concept_id': 'C0332290', 'confidence': 1.0}, {'entity': 'superficial', 'concept_id': 'C0205124', 'confidence': 1.0}, {'entity': 'deep funiculitis', 'concept_id': 'C0241216', 'confidence': 0.7899089455604553}, {'entity': 'perivascular', 'concept_id': 'C0442165', 'confidence': 1.0}, {'entity': 'interstitial regions', 'concept_id': 'C0596790', 'confidence': 0.7848911285400391}], [{'entity': 'involvement', 'concept_id': 'C1314939', 'confidence': 1.0}, {'entity': 'epidermis', 'concept_id': 'C0014520', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_356",
"caption_rating": "9"
},
{
"": "1006969",
"caption": "Presence of sarcoid-like granulomas in the lung of the patient who was taking TNF for ankylosing spondylitis.",
"image_path": "sDFjOtMAYrk_image_8370dccb-c960-4562-b3ff-07df89034286.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['Sarcoid-like granulomas in the lung.']",
"noisy_text": " patients who develop sarcoid-like granulomas, at least in the lung. So maybe the process just takes a little while to resolve after the patient's taken off the drug. Yeah, so the patient, we did all the stains, albeit they're low yield. The patient had no risk factors for TB. They never tested him for TB, though. But they thought clinically, that's not an issue. He got tested for a couple of other things. His ACE was within normal limits, and yeah, nothing. He just removed the drug and said, okay, let's see if this works. And that turned out to be the patient had, he was taking TNF for ankylosing spondylitis. Ankylosing spondylitis, yeah. Coming back to our",
"corrected_text": " patients who develop sarcoid-like granulomas, at least in the lung. So maybe the process just takes a little while to resolve after the patient's taken off the drug. Yeah, so the patient, we did all the stains, albeit they're low yield. The patient had no risk factors for TB. They never tested him for TB, though. But they thought clinically, that's not an issue. He got tested for a couple of other things. His ACE was within normal limits, and yeah, nothing. He just removed the drug and said, okay, let's see if this works. And that turned out to be the patient had, he was taking TNF for ankylosing spondylitis. Ankylosing spondylitis, yeah. Coming back to our",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'sarcoid-like granulomas', 'concept_id': 'C0333419', 'confidence': 0.7742165923118591}, {'entity': 'lung', 'concept_id': 'C0024109', 'confidence': 1.0}, {'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'TNF', 'concept_id': 'C0812246', 'confidence': 1.0}, {'entity': 'ankylosing spondylitis', 'concept_id': 'C0038013', 'confidence': 1.0}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'risk factors', 'concept_id': 'C0035648', 'confidence': 1.0}, {'entity': 'TB', 'concept_id': 'C0041296', 'confidence': 1.0}, {'entity': 'ACE', 'concept_id': 'C0050385', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_357",
"caption_rating": "9"
},
{
"": "1005077",
"caption": "The patient has a focus of partial atrophy in the prostate gland, which is well-circumscribed and contains cystically dilated and partially atrophied glands.",
"image_path": "iklRyY1nBIE_image_7695b497-dc87-4ecb-a881-b7acc24dcf9b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['partial atrophy', 'cystically dilated glands', 'well-circumscribed']",
"noisy_text": " Again, very busy core, crowded core. And then as you come here, you can see cystically dilated glands, partially atrophied glands, fairly well circumscribed. And this doesn't typically occur in isolation. That's another point I want to make. It's very important to look at the background prostate of every patient, not just patients that have prostate cancer, but even patients who have benign prostates. You will see that the backgrounds are different from patient A to patient B to patient C. And it's very important to pay attention to that. Some patients have a lot of partial atrophy. Some patients have a lot of pinnish-like glands. Some patients have a lot of adenosis. So not all patients have the same kind of background prostate, even if there is no cancer there. And that's something else one should be aware of. If you have a patient that has a lot of partial atrophy, you need to raise your threshold very high before you call anything prostate cancer. Otherwise, one will get in trouble. So this is another patient here that has a focus of partial atrophy, here fairly well circumscribed. Some of the glands are a little bigger, but most of them are partially atrophic. Some have cystic atrophy, again, fairly well circumscribed. And if you look at the corresponding immunohistochemical stain in that area, you can see, again, we're having",
"corrected_text": " Again, very busy core, crowded core. And then as you come here, you can see cystically dilated glands, partially atrophied glands, fairly well circumscribed. And this doesn't typically occur in isolation. That's another point I want to make. It's very important to look at the background prostate of every patient, not just patients that have prostate cancer, but even patients who have benign prostates. You will see that the backgrounds are different from patient A to patient B to patient C. And it's very important to pay attention to that. Some patients have a lot of partial atrophy. Some patients have a lot of pinnish-like glands. Some patients have a lot of adenosis. So not all patients have the same kind of background prostate, even if there is no cancer there. And that's something else one should be aware of. If you have a patient that has a lot of partial atrophy, you need to raise your threshold very high before you call anything prostate cancer. Otherwise, one will get in trouble. So this is another patient here that has a focus of partial atrophy, here fairly well circumscribed. Some of the glands are a little bigger, but most of them are partially atrophic. Some have cystic atrophy, again, fairly well circumscribed. And if you look at the corresponding immunohistochemical stain in that area, you can see, again, we're having",
"med_umls_ids": "[[{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'partial', 'concept_id': 'C0728938', 'confidence': 1.0}, {'entity': 'atrophy', 'concept_id': 'C0333641', 'confidence': 1.0}, {'entity': 'prostate gland', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'well-circumscribed', 'concept_id': 'C1707398', 'confidence': 0.9430561065673828}, {'entity': 'cystically', 'concept_id': 'C0205207', 'confidence': 0.6787945628166199}, {'entity': 'dilated', 'concept_id': 'C0700124', 'confidence': 0.9999999403953552}, {'entity': 'atrophied glands', 'concept_id': 'C0333641', 'confidence': 0.752121090888977}], [{'entity': 'background', 'concept_id': 'C1706907', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'backgrounds', 'concept_id': 'C1706907', 'confidence': 0.8927567601203918}, {'entity': 'affect', 'concept_id': 'C0001721', 'confidence': 1.0}, {'entity': 'interpretation', 'concept_id': 'C0459471', 'confidence': 1.0}, {'entity': 'findings', 'concept_id': 'C2607943', 'confidence': 1.0}], [{'entity': 'Patients', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'partial', 'concept_id': 'C0728938', 'confidence': 1.0}, {'entity': 'atrophy', 'concept_id': 'C0333641', 'confidence': 1.0}, {'entity': 'threshold', 'concept_id': 'C0449864', 'confidence': 0.9999999403953552}, {'entity': 'diagnosing', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'prostate cancer', 'concept_id': 'C0376358', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_358",
"caption_rating": "9"
},
{
"": "1004682",
"caption": "Melanin A or Mk1 immunohistochemical stain was performed on a tissue sample.",
"image_path": "8S4LeiO6Bbk_image_d6d12dc2-328c-4877-9819-2d6a22ddd6c5.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['melanocytes']",
"noisy_text": " with that being said, we'll go ahead and move on to slide number two, which was a melanin A or Mk1 immunohistochemical stain of this same piece of tissue. Underneath this bubble here we have our control. This is a melanocytic nevus and we can see in this positive control indeed the stain was working because the melanocytes are stained dark brown. So if we go up and take a look at the biopsy specimen, the tissue in question, I'm going to rotate the slide a little bit. And what we want to focus on",
"corrected_text": " with that being said, we'll go ahead and move on to slide number two, which was a melanin A or Mk1 immunohistochemical stain of this same piece of tissue. Underneath this bubble here we have our control. This is a melanocytic nevus and we can see in this positive control indeed the stain was working because the melanocytes are stained dark brown. So if we go up and take a look at the biopsy specimen, the tissue in question, I'm going to rotate the slide a little bit. And what we want to focus on",
"med_umls_ids": "[[{'entity': 'Melanin A', 'concept_id': 'C0025196', 'confidence': 0.8931530714035034}, {'entity': 'Mk1', 'concept_id': 'C1708816', 'confidence': 1.0}, {'entity': 'immunohistochemical stain', 'concept_id': 'C4317108', 'confidence': 0.9572635889053345}, {'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}], [{'entity': 'melanocytic nevus', 'concept_id': 'C0027962', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}], [{'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'positive control', 'concept_id': 'C1883676', 'confidence': 1.0}, {'entity': 'stained dark brown', 'concept_id': 'C4047948', 'confidence': 0.7432422637939453}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_359",
"caption_rating": "8"
},
{
"": "1006734",
"caption": "Assessment of fibrosis in the lamina propria is important for evaluating chronicity.",
"image_path": "r7OA0Trj5hQ_image_fb327f0b-c96a-4be0-9523-c2062b18c93b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Fibrosis in the lamina propria']",
"noisy_text": " intracellular. Then now, we have to assess the fibrosis in the lamina propria. Again, fibrosis is one of the chronicity criteria. This is normal glands, whereas here, gastric mucosa is the increased reticuline rich. Another thing you have to remember, reticuline strain, you have to say reticuline poor or reticuline rich. You should not say reticuline absent or present. Reticuline will be always present, but is it poor or is it rich? That is the interpretation. This is, again, another indication of chronicity. Another interesting condition, which I saw",
"corrected_text": " intracellular. Then now, we have to assess the fibrosis in the lamina propria. Again, fibrosis is one of the chronicity criteria. This is normal glands, whereas here, gastric mucosa is the increased reticuline rich. Another thing you have to remember, reticulin stain, you have to say reticuline poor or reticuline rich. You should not say reticuline absent or present. Reticuline will be always present, but is it poor or is it rich? That is the interpretation. This is, again, another indication of chronicity. Another interesting condition, which I saw",
"med_umls_ids": "[[{'entity': 'Assessment', 'concept_id': 'C0031809', 'confidence': 1.0}, {'entity': 'fibrosis', 'concept_id': 'C0016059', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'evaluating', 'concept_id': 'C0220825', 'confidence': 0.8878971934318542}, {'entity': 'chronicity', 'concept_id': 'C0547045', 'confidence': 1.0}], [{'entity': 'Increased', 'concept_id': 'C0205217', 'confidence': 1.0}, {'entity': 'reticuline', 'concept_id': 'C0073098', 'confidence': 1.0}, {'entity': 'richness', 'concept_id': 'C3415012', 'confidence': 0.5465915203094482}, {'entity': 'gastric mucosa', 'concept_id': 'C0017136', 'confidence': 1.0}, {'entity': 'indication', 'concept_id': 'C0392360', 'confidence': 1.0}, {'entity': 'chronicity', 'concept_id': 'C0547045', 'confidence': 1.0}], [{'entity': 'Reticulin stain', 'concept_id': 'C1294006', 'confidence': 1.0}, {'entity': 'reticuline', 'concept_id': 'C0073098', 'confidence': 1.0}, {'entity': 'poor', 'concept_id': 'C0032854', 'confidence': 1.0}, {'entity': 'reticuline', 'concept_id': 'C0073098', 'confidence': 1.0}, {'entity': 'rich', 'concept_id': 'C0699759', 'confidence': 1.0}, {'entity': 'absent', 'concept_id': 'C0332197', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_360",
"caption_rating": "8"
},
{
"": "1006735",
"caption": "Reticulin stain should be interpreted as reticuline poor or reticuline rich, not absent or present.",
"image_path": "r7OA0Trj5hQ_image_fb327f0b-c96a-4be0-9523-c2062b18c93b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Fibrosis in the lamina propria']",
"noisy_text": " intracellular. Then now, we have to assess the fibrosis in the lamina propria. Again, fibrosis is one of the chronicity criteria. This is normal glands, whereas here, gastric mucosa is the increased reticuline rich. Another thing you have to remember, reticuline strain, you have to say reticuline poor or reticuline rich. You should not say reticuline absent or present. Reticuline will be always present, but is it poor or is it rich? That is the interpretation. This is, again, another indication of chronicity. Another interesting condition, which I saw",
"corrected_text": " intracellular. Then now, we have to assess the fibrosis in the lamina propria. Again, fibrosis is one of the chronicity criteria. This is normal glands, whereas here, gastric mucosa is the increased reticuline rich. Another thing you have to remember, reticulin stain, you have to say reticuline poor or reticuline rich. You should not say reticuline absent or present. Reticuline will be always present, but is it poor or is it rich? That is the interpretation. This is, again, another indication of chronicity. Another interesting condition, which I saw",
"med_umls_ids": "[[{'entity': 'Assessment', 'concept_id': 'C0031809', 'confidence': 1.0}, {'entity': 'fibrosis', 'concept_id': 'C0016059', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'evaluating', 'concept_id': 'C0220825', 'confidence': 0.8878971934318542}, {'entity': 'chronicity', 'concept_id': 'C0547045', 'confidence': 1.0}], [{'entity': 'Increased', 'concept_id': 'C0205217', 'confidence': 1.0}, {'entity': 'reticuline', 'concept_id': 'C0073098', 'confidence': 1.0}, {'entity': 'richness', 'concept_id': 'C3415012', 'confidence': 0.5465915203094482}, {'entity': 'gastric mucosa', 'concept_id': 'C0017136', 'confidence': 1.0}, {'entity': 'indication', 'concept_id': 'C0392360', 'confidence': 1.0}, {'entity': 'chronicity', 'concept_id': 'C0547045', 'confidence': 1.0}], [{'entity': 'Reticulin stain', 'concept_id': 'C1294006', 'confidence': 1.0}, {'entity': 'reticuline', 'concept_id': 'C0073098', 'confidence': 1.0}, {'entity': 'poor', 'concept_id': 'C0032854', 'confidence': 1.0}, {'entity': 'reticuline', 'concept_id': 'C0073098', 'confidence': 1.0}, {'entity': 'rich', 'concept_id': 'C0699759', 'confidence': 1.0}, {'entity': 'absent', 'concept_id': 'C0332197', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_361",
"caption_rating": "8"
},
{
"": "1008751",
"caption": "CD68 is strongly positive in xanthoma.",
"image_path": "r7OA0Trj5hQ_image_8c27381b-ee6a-42e7-844a-c61938edde63.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['young males', 'inflammatory bowel disease', 'lamina propria', 'distinct cell border', 'foamy cytoplasm', 'centrally placed nucleus', 'gastric xanthoma', 'young males', 'inflammatory bowel disease', 'lamina propria', 'distinct cell border', 'foamy cytoplasm', 'centrally placed nucleus', 'gastric xanthoma']",
"noisy_text": " It is commonly seen in young males, and they present with the signs and symptoms of inflammatory bowel disease. Interesting condition. Here, the lamina propria is full of cells with a distinct cell border, abundant foamy cytoplasm, most of the time centrally placed nucleus. Sometimes it is pushed to the periphery. The central nuclear placement is very important for a diagnosis of xanthoma. For a signet cells, it will be predominantly peripherally pushed nucleus. And when you have doubt, you do a CD68, which will be strongly positive. And so this is a gastric xanthoma. Here, it",
"corrected_text": " It is commonly seen in young males, and they present with the signs and symptoms of inflammatory bowel disease. Interesting condition. Here, the lamina propria is full of cells with a distinct cell border, abundant foamy cytoplasm, most of the time centrally placed nucleus. Sometimes it is pushed to the periphery. The central nuclear placement is very important for a diagnosis of xanthoma. For a signet ring cells, it will be predominantly peripherally pushed nucleus. And when you have doubt, you do a CD68, which will be strongly positive. And so this is a gastric xanthoma. Here, it",
"med_umls_ids": "[[{'entity': 'Xanthoma', 'concept_id': 'C0302314', 'confidence': 1.0}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'young', 'concept_id': 'C0332239', 'confidence': 1.0}, {'entity': 'males', 'concept_id': 'C0086582', 'confidence': 1.0}, {'entity': 'signs', 'concept_id': 'C0220912', 'confidence': 0.9999999403953552}, {'entity': 'symptoms', 'concept_id': 'C0683368', 'confidence': 1.0}, {'entity': 'inflammatory bowel disease', 'concept_id': 'C0021390', 'confidence': 1.0}], [{'entity': 'Lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'cell border', 'concept_id': 'C0205284', 'confidence': 0.773768424987793}, {'entity': 'foamy cytoplasm', 'concept_id': 'C0010834', 'confidence': 0.7207725048065186}, {'entity': 'centrally', 'concept_id': 'C0205099', 'confidence': 0.7070305943489075}, {'entity': 'nucleus', 'concept_id': 'C0007610', 'confidence': 1.0}, {'entity': 'gastric xanthoma', 'concept_id': 'C1282522', 'confidence': 1.0}], [{'entity': 'CD68', 'concept_id': 'C0108799', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'xanthoma', 'concept_id': 'C0302314', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_362",
"caption_rating": "8"
},
{
"": "1004519",
"caption": "Patient likely has STI proctitis with mild inflammation and cryptitis.",
"image_path": "sDFjOtMAYrk_image_57e4dcdd-95ed-430b-a7bd-89dff554c7d0.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['inflammation', 'histiocytes', 'plasma cells', 'neutrophils', 'lymphocytes', 'cryptitis']",
"noisy_text": " This is what I'm used to seeing in patients with STI proctitis, just a little bit in the way of inflammation, maybe some cryptitis here and there, but not to the degree that we saw in the previous case. The inflammation consists of, in the lamina propria, some histiocytes, plasma cells, and some neutrophils and lymphocytes. And some cases have predominantly plasma cells in the lamina propria. Some cells have predominantly histiocytes in the lamina propria. I used to think when we started recognizing these that",
"corrected_text": " This is what I'm used to seeing in patients with STI proctitis, just a little bit in the way of inflammation, maybe some cryptitis here and there, but not to the degree that we saw in the previous case. The inflammation consists of, in the lamina propria, some histiocytes, plasma cells, and some neutrophils and lymphocytes. And some cases have predominantly plasma cells in the lamina propria. Some cells have predominantly histiocytes in the lamina propria. I used to think when we started recognizing these that",
"med_umls_ids": "[[{'entity': 'Patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'STI', 'concept_id': 'C0036916', 'confidence': 1.0}, {'entity': 'proctitis', 'concept_id': 'C0033246', 'confidence': 0.9999999403953552}, {'entity': 'mild', 'concept_id': 'C1513302', 'confidence': 1.0}, {'entity': 'inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}, {'entity': 'cryptitis', 'concept_id': 'C1394254', 'confidence': 0.9999998807907104}], [{'entity': 'Inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_363",
"caption_rating": "8"
},
{
"": "1006871",
"caption": "Crypt microabscesses and cryptitis are present.",
"image_path": "sDFjOtMAYrk_image_b7a893c4-397f-4f99-9e3d-16a1e788f7d8.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['bloody bowel movement', 'IBD evaluation', 'architectural distortion', 'missing gland', 'bifurcation', 'crypt dropout', 'granulation tissue', 'crypt microabscesses', 'cryptitis']",
"noisy_text": " So moving along to number three, Hamar. Can you read the history please? Yeah. It's 44 years old HIV male with a bloody bowel movement and polio arthritis condition concerned about IBD. Okay. So are you gonna, are we gonna stamp him with IBD? Not yet. No, because we already saw IBD, right? So what would you say about the architectural distortion? So some sections, there's no distortion, but in some area we can see there's a lot of missing gland and the distortion of the maybe some bifurcation, right? Yeah. So some bifurcation, some crypt dropout, lots of granulation tissue, and we have plenty in the way of activity. Yeah. So I would say more than I'm used to seeing in this process. So good crypt micro abscesses and cryptitis. And then bear",
"corrected_text": " So moving along to number three, Hamar. Can you read the history please? Yeah. It's 44 years old HIV male with a bloody bowel movement and polio arthritis condition concerned about IBD. Okay. So are you gonna, are we gonna stamp him with IBD? Not yet. No, because we already saw IBD, right? So what would you say about the architectural distortion? So some sections, there's no distortion, but in some area we can see there's a lot of missing gland and the distortion of the maybe some bifurcation, right? Yeah. So some bifurcation, some crypt dropout, lots of granulation tissue, and we have plenty in the way of activity. Yeah. So I would say more than I'm used to seeing in this process. So good crypt micro abscesses and cryptitis. And then bear",
"med_umls_ids": "[[{'entity': 'HIV-positive', 'concept_id': 'C4287934', 'confidence': 0.6893086433410645}, {'entity': 'male', 'concept_id': 'C0086582', 'confidence': 1.0}, {'entity': 'bloody bowel movement', 'concept_id': 'C0151594', 'confidence': 0.9999998807907104}, {'entity': 'post-polio syndrome', 'concept_id': 'C0080040', 'confidence': 1.0}, {'entity': 'evaluated', 'concept_id': 'C0220825', 'confidence': 1.0}, {'entity': 'IBD', 'concept_id': 'C0021390', 'confidence': 1.0}], [{'entity': 'Architectural distortion', 'concept_id': 'C2826609', 'confidence': 1.0}, {'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'bifurcation', 'concept_id': 'C0184906', 'confidence': 0.9999999403953552}, {'entity': 'crypt', 'concept_id': 'C1880192', 'confidence': 1.0}, {'entity': 'dropout', 'concept_id': 'C0013135', 'confidence': 1.0}, {'entity': 'granulation tissue', 'concept_id': 'C0018180', 'confidence': 1.0}], [{'entity': 'Crypt', 'concept_id': 'C1880192', 'confidence': 1.0}, {'entity': 'microabscesses', 'concept_id': 'C0333373', 'confidence': 0.879554271697998}, {'entity': 'cryptitis', 'concept_id': 'C1394254', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_364",
"caption_rating": "8"
},
{
"": "1007588",
"caption": "A person with sarcoidosis developed a severe granulomatous reaction from tattoo pigment on their eyelid.",
"image_path": "LlPaENuqzVQ_image_866e3517-bd3e-4c28-ae08-a37b8985372c.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['eyelid tattoo', 'sarcoid granulomatous reaction', 'rosacea', 'nodular infiltrate', 'sarcoid morphology', 'histiocytes', 'eyelid tattoo', 'sarcoid granulomatous reaction', 'rosacea', 'nodular infiltrate', 'sarcoid morphology', 'histiocytes']",
"noisy_text": " Somebody got one of these eyelid tattoos or whatever and they also had sarcoidosis and guess what? They got this horrible kevnerized sarcoid from this tattoo pigment. So this is a person that I think was a African-American person that got a tattoo and then you got a horrible sarcoidal granulomatous reaction. So, but you can sometimes see rosacea look like this. It's not usually this amount of it. And it'd be really, then this is sufficiently deep. You know, that's going down deep here. And this would be a nodular infiltrate with sarcoidal morphology, these histiocytes here. So that's a nice example of sarcoid to kind of",
"corrected_text": " Somebody got one of these eyelid tattoos or whatever and they also had sarcoidosis and guess what? They got this severe kevnerized sarcoid from this tattoo pigment. So this is a person that I think was a African-American person that got a tattoo and then you got a severe sarcoidal granulomatous reaction. So, but you can sometimes see rosacea look like this. It's not usually this amount of it. And it'd be really, then this is sufficiently deep. You know, that's going down deep here. And this would be a nodular infiltrate with sarcoidal morphology, these histiocytes here. So that's a nice example of sarcoid to kind of",
"med_umls_ids": "[[{'entity': 'person', 'concept_id': 'C0027361', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'granulomatous reaction', 'concept_id': 'C0439667', 'confidence': 0.856907308101654}, {'entity': 'tattoo pigment', 'concept_id': 'C0031911', 'confidence': 0.674771249294281}, {'entity': 'eyelid', 'concept_id': 'C0015426', 'confidence': 1.0}], [{'entity': 'Rosacea', 'concept_id': 'C0035854', 'confidence': 1.0}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}], [{'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'nodular infiltrate', 'concept_id': 'C0241130', 'confidence': 0.840809166431427}, {'entity': 'sarcoid', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_365",
"caption_rating": "8"
},
{
"": "1007653",
"caption": "H. pylori can be best visualized with careful examination of H&E stain.",
"image_path": "r7OA0Trj5hQ_image_753d9b8c-367b-4d02-9609-187d48ccfe78.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Goblet cells in gastric mucosa', 'Peritoneal cells in the body of the stomach']",
"noisy_text": " So the best stain for H. pylori is careful examination of H&E. Here H&E picture showing goblet cells in a gastric mucosa. The goblet cells are taking blue color, in algean blue, whereas the gastric epithelium is taking the PAS color. So this is algean blue PAS, intersternal metaplasia of the gastric mucosa. Here the history is this biopsy is taken from the body of the stomach. In the body of the stomach, you have to see a lot of fried eggs. These are all the peritoneal cells in addition to mucincycletine cells and chief cells. These are the peritoneal cells. When you",
"corrected_text": " So the best stain for H. pylori is careful examination of H&E. Here H&E picture showing goblet cells in a gastric mucosa. The goblet cells are taking blue color, in Alcian blue, whereas the gastric epithelium is taking the PAS color. So this is Alcian blue PAS, intestinal metaplasia of the gastric mucosa. Here the history is this biopsy is taken from the body of the stomach. In the body of the stomach, you have to see a lot of fried eggs. These are all the peritoneal cells in addition to mucincycletine cells and chief cells. These are the peritoneal cells. When you",
"med_umls_ids": "[[{'entity': 'H. pylori', 'concept_id': 'C0079488', 'confidence': 1.0}, {'entity': 'visualized', 'concept_id': 'C0234621', 'confidence': 1.0}, {'entity': 'examination', 'concept_id': 'C0031809', 'confidence': 1.0}, {'entity': 'H&E stain', 'concept_id': 'C0523207', 'confidence': 1.0}], [{'entity': 'image', 'concept_id': 'C1696103', 'confidence': 1.0}, {'entity': 'goblet cells', 'concept_id': 'C0506994', 'confidence': 0.9999999403953552}, {'entity': 'gastric mucosa', 'concept_id': 'C0017136', 'confidence': 1.0}, {'entity': 'blue color', 'concept_id': 'C1260957', 'confidence': 1.0}, {'entity': 'Alcian blue', 'concept_id': 'C0001933', 'confidence': 1.0}, {'entity': 'PAS', 'concept_id': 'C0030125', 'confidence': 1.0}, {'entity': 'color', 'concept_id': 'C0009393', 'confidence': 1.0}, {'entity': 'gastric epithelium', 'concept_id': 'C0227208', 'confidence': 1.0}], [{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'body', 'concept_id': 'C0227230', 'confidence': 1.0}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'peritoneal cells', 'concept_id': 'C0031153', 'confidence': 0.7749612331390381}, {'entity': 'mucincycletine cells', 'concept_id': 'C0007586', 'confidence': 0.6177586317062378}, {'entity': 'chief cells', 'concept_id': 'C1516470', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_366",
"caption_rating": "8"
},
{
"": "1006015",
"caption": "The lesion is diffusely dissecting throughout the dermis.",
"image_path": "LlPaENuqzVQ_image_2beb252a-0e73-4aee-92e8-acad841e9e79.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['Lesion dissecting throughout the dermis', 'No nerve involvement observed', 'Sclerosing epithelial neoplasms', 'Deep biopsy necessary for definitive diagnosis']",
"noisy_text": " So this thing is kind of dissecting diffusely throughout the dermis here. I don't see any nerve involvement in this case but it's very common to get neurotropism and microcystic anexal carcinoma. So I'm not gonna belabor the differential diagnosis of the sclerosing epithelial neoplasms but you need to know that. And you need to know that you need to take a good deep biopsy in order to make a definitive diagnosis or you won't get a definitive diagnosis. And there's no stain that helps. Everybody says, oh, you can do a T63 or this and the other, looking for Merkel cells or CK20. I've never found any of these things to be helpful. And the other differential that sometimes comes up is the",
"corrected_text": " So this thing is kind of dissecting diffusely throughout the dermis here. I don't see any nerve involvement in this case but it's very common to get neurotropism and microcystic adnexal carcinoma. So I'm not gonna belabor the differential diagnosis of the sclerosing epithelial neoplasms but you need to know that. And you need to know that you need to take a good deep biopsy in order to make a definitive diagnosis or you won't get a definitive diagnosis. And there's no stain that helps. Everybody says, oh, you can do a T63 or this and the other, looking for Merkel cells or CK20. I've never found any of these things to be helpful. And the other differential that sometimes comes up is the",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'diffusely', 'concept_id': 'C0205219', 'confidence': 0.8011853098869324}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}], [{'entity': 'Neurotropism', 'concept_id': 'C1518304', 'confidence': 1.0}, {'entity': 'microcystic adnexal carcinoma', 'concept_id': 'C0346027', 'confidence': 1.0}, {'entity': 'nerves', 'concept_id': 'C0027740', 'confidence': 1.0}], [{'entity': 'deep biopsy', 'concept_id': 'C0185285', 'confidence': 0.8188310265541077}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'sclerosing', 'concept_id': 'C0036426', 'confidence': 0.833010733127594}, {'entity': 'epithelial neoplasms', 'concept_id': 'C1368683', 'confidence': 0.9999999403953552}], [{'entity': 'No stain', 'concept_id': 'C0038128', 'confidence': 0.8399802446365356}, {'entity': 'diagnosing', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'sclerosing', 'concept_id': 'C0036426', 'confidence': 0.833010733127594}, {'entity': 'epithelial neoplasms', 'concept_id': 'C1368683', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_367",
"caption_rating": "9"
},
{
"": "1008267",
"caption": "Lymphocytic infiltrate is present, possibly due to inflammation.",
"image_path": "LlPaENuqzVQ_image_1eed5e29-5b3c-4745-8e1f-b3fd32d86024.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['lymphocytic infiltrate', 'inflammation', 'skin']",
"noisy_text": " So I'll say that Schmutz here, but it may be something other than that. Yeah, kind of the head scratcher a little bit. So we have the lymphocytic infiltrate over here. You know, that's I think that's real. I mean, it's probably some type of inflammation that may have occurred possibly because something is it's reacting to something, but there's definitely something else going on besides that. So this doesn't look normal in the skin, does it? Is that, yeah, those, yeah. I mean, yeah, I can't really readily identify what cell type those are. It does a little epithelioid. Where they",
"corrected_text": " So I'll say that Schmutz here, but it may be something other than that. Yeah, kind of the head scratcher a little bit. So we have the lymphocytic infiltrate over here. You know, that's I think that's real. I mean, it's probably some type of inflammation that may have occurred possibly because something is it's reacting to something, but there's definitely something else going on besides that. So this doesn't look normal in the skin, does it? Is that, yeah, those, yeah. I mean, yeah, I can't really readily identify what cell type those are. It does a little epithelioid. Where they",
"med_umls_ids": "[[{'entity': 'Lymphocytic infiltrate', 'concept_id': 'C0333386', 'confidence': 1.0}, {'entity': 'inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}], [{'entity': 'Something', 'concept_id': 'C3843412', 'confidence': 0.7484908699989319}, {'entity': 'inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}], [{'entity': 'skin', 'concept_id': 'C0444099', 'confidence': 1.0}], [{'entity': 'Cell type', 'concept_id': 'C0007634', 'confidence': 1.0}, {'entity': 'identified', 'concept_id': 'C0205396', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_368",
"caption_rating": "8"
},
{
"": "1009265",
"caption": "Tuberculoid form of leprosy can cause sarcoid granulomatous inflammation.",
"image_path": "udoW6VSqsm4_image_f5d32450-1d57-43e4-a560-1a822381f3a3.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['sarcoid granulomatous inflammation', 'involvement around nerves']",
"noisy_text": " That's the tuberculoid. Yeah, good. The tuberculoid form of leprosy gives you sarcoidal granulomatous inflammation. It's elongated. Very good. That's exactly right. What else can give you sarcoidal granulomatous inflammation? Can I ask a quick question about the sarcoid with the two... The nansins? So, I had a case, I saw a case that looked kind of horizontal, but it was sarcoid. And so, what other ways can you tell? Sometimes it can be difficult, but usually you're going to see involvement around nerves damaged nerves. You're about to get sarcoidal granulomatous inflammation. They always have very high risk inflammatory reactions. They just wipe out the nerves. So, that's helpful. Wasn't",
"corrected_text": " That's the tuberculoid. Yeah, good. The tuberculoid form of leprosy gives you sarcoidal granulomatous inflammation. It's elongated. Very good. That's exactly right. What else can give you sarcoidal granulomatous inflammation? Can I ask a quick question about the sarcoid with the two... The sarcoidosis? So, I had a case, I saw a case that looked kind of horizontal, but it was sarcoid. And so, what other ways can you tell? Sometimes it can be difficult, but usually you're going to see involvement around nerves damaged nerves. You're about to get sarcoidal granulomatous inflammation. They always have very high risk inflammatory reactions. They just wipe out the nerves. So, that's helpful. Wasn't",
"med_umls_ids": "[[{'entity': 'Tuberculoid', 'concept_id': 'C0544783', 'confidence': 0.8459237217903137}, {'entity': 'leprosy', 'concept_id': 'C0023343', 'confidence': 1.0}, {'entity': 'sarcoid', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'granulomatous inflammation', 'concept_id': 'C0553697', 'confidence': 1.0}], [{'entity': 'Involvement', 'concept_id': 'C1314939', 'confidence': 1.0}, {'entity': 'damaged nerves', 'concept_id': 'C3887709', 'confidence': 0.8087002038955688}, {'entity': 'sarcoid', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'granulomatous inflammation', 'concept_id': 'C0553697', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_369",
"caption_rating": "8"
},
{
"": "1008500",
"caption": "Synovial sarcoma can have well-differentiated areas that resemble low-grade fibromyxoid sarcoma.",
"image_path": "QDb68_G1HR4_image_152660c1-7a02-4527-a98a-a5561a3fa697.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['synovial sarcoma', 'low-grade fibromyxoid sarcoma', 'FUS gene rearrangement']",
"noisy_text": " but I've seen very rare examples where there were very well differentiated areas in a synovial sarcoma that kind of had a fibrous look and looked similar to low-grade fibromyxoid sarcoma. So in that case, obviously you could use other stains like keratins and if you like TLE1 you could do that. And then in the end, if you have trouble, molecular pathology can help us out. Like I said earlier, these tumors, low-grade fibromyxoid sarcoma is defined by a translocation. The most common translocation is the translocation 716 which is between the genes FUS and CREB3L2. And there's also a small subset of these that have an alternate translocation which is between the FUS gene and the CREB3L1 gene. So FUS-CREB3L2 or FUS-CREB3L1 gene fusion can support the diagnosis. So you could use break apart fish for FUS. If the tumor looks like this and FUS is positive for FUS rearrangement, then you should be pretty good in calling it a low-grade fibromyxoid sarcoma. But do be aware that there are many other tumors in soft tissue pathology that have FUS rearrangements, myxoid liposarcoma and others. They usually have a different histologic appearance. So that's why you can never use, at least in my opinion, you shouldn't use molecular pathology by itself. You have to couple it with the clinical scenario and the histologic features and the immunostain findings. Put",
"corrected_text": " but I've seen very rare examples where there were very well differentiated areas in a synovial sarcoma that kind of had a fibrous look and looked similar to low-grade fibromyxoid sarcoma. So in that case, obviously you could use other stains like keratins and if you like TLE1 you could do that. And then in the end, if you have trouble, molecular pathology can help us out. Like I said earlier, these tumors, low-grade fibromyxoid sarcoma is defined by a translocation. The most common translocation is the translocation 716 which is between the genes FUS and CREB3L2. And there's also a small subset of these that have an alternate translocation which is between the FUS gene and the CREB3L1 gene. So FUS-CREB3L2 or FUS-CREB3L1 gene fusion can support the diagnosis. So you could use break apart fish for FUS. If the tumor looks like this and FUS is positive for FUS gene rearrangement, then you should be pretty good in calling it a low-grade fibromyxoid sarcoma. But do be aware that there are many other tumors in soft tissue pathology that have FUS gene rearrangements, myxoid liposarcoma and others. They usually have a different histologic appearance. So that's why you can never use, at least in my opinion, you shouldn't use molecular pathology by itself. You have to couple it with the clinical scenario and the histologic features and the immunohistochemistry findings. Put",
"med_umls_ids": "[[{'entity': 'Synovial sarcoma', 'concept_id': 'C0039101', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}], [{'entity': 'Keratin', 'concept_id': 'C0010803', 'confidence': 1.0}, {'entity': 'TLE1', 'concept_id': 'C1420752', 'confidence': 1.0}, {'entity': 'stains', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'differentiate', 'concept_id': 'C0205615', 'confidence': 0.9999998807907104}, {'entity': 'synovial sarcoma', 'concept_id': 'C0039101', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}], [{'entity': 'Low-grade fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.9999998807907104}, {'entity': 'translocation', 'concept_id': 'C0040715', 'confidence': 1.0}, {'entity': 'translocation', 'concept_id': 'C0040715', 'confidence': 1.0}, {'entity': 'FUS', 'concept_id': 'C0268696', 'confidence': 1.0}, {'entity': 'CREB3L2', 'concept_id': 'C1428221', 'confidence': 0.9999998807907104}, {'entity': 'genes', 'concept_id': 'C0017337', 'confidence': 1.0}], [{'entity': 'Break apart FISH', 'concept_id': 'C3831569', 'confidence': 0.7467014789581299}, {'entity': 'FUS', 'concept_id': 'C0268696', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}], [{'entity': 'Molecular pathology', 'concept_id': 'C0596962', 'confidence': 1.0}, {'entity': 'coupled', 'concept_id': 'C1948027', 'confidence': 1.0}, {'entity': 'clinical scenario', 'concept_id': 'C0205210', 'confidence': 0.6381967067718506}, {'entity': 'histologic features', 'concept_id': 'C1301121', 'confidence': 0.816085159778595}, {'entity': 'immunohistochemistry', 'concept_id': 'C0021044', 'confidence': 0.9999998807907104}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_370",
"caption_rating": "8"
},
{
"": "1008864",
"caption": "Abnormal maturation of keratinocytes with full thickness keratinocytic atypia and hyperchromatic cells within the stratum corneum.",
"image_path": "8S4LeiO6Bbk_image_e5790862-3f0c-49bc-bd05-fc6c6a29c969.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['abnormal maturation of keratinocytes', 'hyperchromatic cells', 'melanin pigment', 'dendritic melanocytes', 'abnormal maturation of keratinocytes', 'hyperchromatic cells', 'melanin pigment', 'dendritic melanocytes']",
"noisy_text": " I think would be reasonable considerations. However, if we move to higher power and begin to study the epidermis a little bit more carefully we can see that there's clear-cut abnormal maturation here. We've got full thickness keratinocytic atypia with nucleic acid or pleomorphic and hyperchromatic. There is abnormal maturation with even abnormal hyperchromatic perikaratotic cells within the stratum corneum. There's an increased amount of melanin pigment pressed within the basal layer and we can see that we've got an increased amount of melanin pigment and even a few dendritic melanocytes within the epidermis and so what we've got here is an example of pigmented Bowen's disease or pigmented squamous cell carcinoma. One could see similar changes in lesions",
"corrected_text": " I think would be reasonable considerations. However, if we move to higher power and begin to study the epidermis a little bit more carefully we can see that there's clear-cut abnormal maturation of keratinocytes here. We've got full thickness keratinocytic atypia with nucleic acid or pleomorphic and hyperchromatic. There is abnormal maturation with even abnormal hyperchromatic parakeratotic cells within the stratum corneum. There's an increased amount of melanin pigment pressed within the basal layer and we can see that we've got an increased amount of melanin pigment and even a few dendritic melanocytes within the epidermis and so what we've got here is an example of pigmented Bowen 's disease's disease or pigmented squamous cell carcinoma. One could see similar changes in lesions",
"med_umls_ids": "[[{'entity': 'Abnormal', 'concept_id': 'C0205161', 'confidence': 1.0}, {'entity': 'maturation', 'concept_id': 'C0678723', 'confidence': 1.0}, {'entity': 'keratinocytes', 'concept_id': 'C0022567', 'confidence': 1.0}, {'entity': 'thickness', 'concept_id': 'C1280412', 'confidence': 1.0}, {'entity': 'keratinocytic atypia', 'concept_id': 'C0741302', 'confidence': 0.6335055828094482}, {'entity': 'hyperchromatic cells', 'concept_id': 'C0333911', 'confidence': 0.823300302028656}, {'entity': 'stratum corneum', 'concept_id': 'C0221921', 'confidence': 1.0}], [{'entity': 'Increased', 'concept_id': 'C0205217', 'confidence': 1.0}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}, {'entity': 'pigment', 'concept_id': 'C0031911', 'confidence': 1.0}, {'entity': 'dendritic melanocytes', 'concept_id': 'C0025201', 'confidence': 0.7694142460823059}, {'entity': 'epidermis', 'concept_id': 'C0014520', 'confidence': 1.0}], [{'entity': 'Diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'Bowen\u2019s disease', 'concept_id': 'C0006079', 'confidence': 0.9730859994888306}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'squamous cell carcinoma', 'concept_id': 'C0007137', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_371",
"caption_rating": "9"
},
{
"": "1007487",
"caption": "Disseminated GA in older individuals may be a perineoplastic process.",
"image_path": "udoW6VSqsm4_image_c9d6bbe3-a848-49a8-acf9-006cbe06a31d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['small individual papules', 'central crust', 'perioral skin', 'granulomatous condition', 'palisade granulostermatitis', 'neutrophilic dermatosis', 'older individuals', 'perineoplastic process']",
"noisy_text": " Yeah, this would be more kind of the classic one, probably. What else? Here's the classic one clinically. What if there's small individual papules that have a central crust in them, often on apral skin? We have had several cases of the disseminated GA, but I'm not sure if they didn't have a crust. So, what's the type that had it? Perforating? Perforating GA. Perforating GA, good. So, this was granulomanuary. There's one other condition that gives you palisade granulostermatitis like this, but it also gives you some neutrophils infiltrate. That palisade and neutrophilic granulostermatitis, that's another thing that you at least have to think about when you see GA. If you see an older person that's got disseminated GA, think about it as a perineoplastic process. Sometimes you",
"corrected_text": " Yeah, this would be more kind of the classic one, probably. What else? Here's the classic one clinically. What if there's small individual papules that have a central crust in them, often on perioral skin? We have had several cases of the disseminated GA, but I'm not sure if they didn't have a crust. So, what's the type that had it? Perforating? Perforating GA. Perforating GA, good. So, this was granulomatous. There's one other condition that gives you palisade granulostermatitis like this, but it also gives you some neutrophils infiltrate. That palisade and neutrophilic dermatosis, that's another thing that you at least have to think about when you see GA. If you see an older person that's got disseminated GA, think about it as a perineoplastic process. Sometimes you",
"med_umls_ids": "[[{'entity': 'Clinical', 'concept_id': 'C0205210', 'confidence': 1.0}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'skin condition', 'concept_id': 'C1719933', 'confidence': 1.0}, {'entity': 'individual', 'concept_id': 'C0027361', 'confidence': 1.0}, {'entity': 'papules', 'concept_id': 'C0332563', 'confidence': 0.9999999403953552}, {'entity': 'central crust', 'concept_id': 'C0205204', 'confidence': 0.7633819580078125}, {'entity': 'perioral skin', 'concept_id': 'C0448802', 'confidence': 0.8075158596038818}], [{'entity': 'Perforating', 'concept_id': 'C0549099', 'confidence': 1.0}, {'entity': 'GA', 'concept_id': 'C0002915', 'confidence': 1.0}, {'entity': 'granulomatous condition', 'concept_id': 'C0439667', 'confidence': 0.8219265341758728}, {'entity': 'palisade', 'concept_id': 'C0331512', 'confidence': 0.8241410255432129}, {'entity': 'granulostermatitis', 'concept_id': 'C0743086', 'confidence': 0.7311265468597412}], [{'entity': 'Neutrophilic dermatosis', 'concept_id': 'C1142272', 'confidence': 1.0}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'GA', 'concept_id': 'C0002915', 'confidence': 1.0}], [{'entity': 'Disseminated', 'concept_id': 'C0205221', 'confidence': 1.0}, {'entity': 'GA', 'concept_id': 'C0002915', 'confidence': 1.0}, {'entity': 'older', 'concept_id': 'C0337524', 'confidence': 0.7771234512329102}, {'entity': 'individuals', 'concept_id': 'C0027361', 'confidence': 0.8766164779663086}, {'entity': 'perineoplastic process', 'concept_id': 'C0027671', 'confidence': 0.8771522045135498}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_372",
"caption_rating": "8"
},
{
"": "1007922",
"caption": "The first area is a branch of the mesenteric vein, while the second area is a branch of the mesenteric artery.",
"image_path": "r7OA0Trj5hQ_image_d0dd8936-2bca-4afa-a3fc-2a4f2a0d35bd.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Internal elastic lamina in one area', 'Branch of mesenteric artery', 'Branch of mesenteric vein', 'Idiopathic myointimal hyperplasia of mesenteric vein']",
"noisy_text": " And you can see here, there is no internal elastic lamina, whereas here, there is an internal elastic lamina. So this is a branch of mesenteric artery, whereas this is a branch of mesenteric vein. And there is a condition called as idiopathic myointimal hyperplasia of the mesenteric vein. I don't know how many of you have heard this company. There's a company called His Master's Voice, which we call HMV before, His Master's Voice. This dog is listening to the master's voice here. And another funny question there, is this dog male or female? Because it is His Master's Voice, it is male. I know it is not pathology, but talking up too",
"corrected_text": " And you can see here, there is no internal elastic lamina, whereas here, there is an internal elastic lamina. So this is a branch of mesenteric artery, whereas this is a branch of mesenteric vein. And there is a condition called as idiopathic myointimal hyperplasia of mesenteric vein of the mesenteric vein. I don't know how many of you have heard this company. There's a company called His Master's Voice, which we call HMV before, His Master's Voice. This dog is listening to the master's voice here. And another funny question there, is this dog male or female? Because it is His Master's Voice, it is male. I know it is not pathology, but talking up too",
"med_umls_ids": "[[{'entity': 'internal elastic lamina', 'concept_id': 'C1180561', 'confidence': 1.0}, {'entity': 'area', 'concept_id': 'C0017446', 'confidence': 1.0}, {'entity': 'internal elastic lamina', 'concept_id': 'C1180561', 'confidence': 1.0}, {'entity': 'area', 'concept_id': 'C0017446', 'confidence': 1.0}], [{'entity': 'area', 'concept_id': 'C0017446', 'confidence': 1.0}, {'entity': 'branch', 'concept_id': 'C0205384', 'confidence': 1.0}, {'entity': 'mesenteric vein', 'concept_id': 'C0025473', 'confidence': 1.0}, {'entity': 'area', 'concept_id': 'C0017446', 'confidence': 1.0}, {'entity': 'branch', 'concept_id': 'C0205384', 'confidence': 1.0}, {'entity': 'mesenteric artery', 'concept_id': 'C0025465', 'confidence': 1.0}], [{'entity': 'Idiopathic myointimal hyperplasia', 'concept_id': 'C0333978', 'confidence': 0.8139097094535828}, {'entity': 'mesenteric vein', 'concept_id': 'C0025473', 'confidence': 1.0}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_373",
"caption_rating": "7"
},
{
"": "1008724",
"caption": "Targetoid hemosiderotic hemangioma is the likely diagnosis.",
"image_path": "8S4LeiO6Bbk_image_7a1fbb54-1a16-4c4d-ba48-7199d6c67247.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['siderophages']",
"noisy_text": " by these dilated vascular channels. Let's look at the bottom piece, which frequently do contain these papillary projections, which protrude into the lumina, these plump endothelial cells, and then at the periphery, more compressed vascular channels, which dissect between collagen bundles. And it's at the periphery one frequently sees extravasated erythrocytes, siderophages, and an infiltrate of lymphocytes. So targetoid hemocidiotic hemangioma. Sometimes it can be quite difficult to distinguish these from patch gage stage Kaposi's. And again, HHV8 stain will help you because these are routinely negative for HHVA and the Kaposi's, of course, will always stain with an HHV8 stain. And we will close out our discussion with slide number 12, which is kind of a cool case to end on. And we have two pieces of tissue here. And if",
"corrected_text": " by these dilated vascular channels. Let's look at the bottom piece, which frequently do contain these papillary projections, which protrude into the lumina, these plump endothelial cells, and then at the periphery, more compressed vascular channels, which dissect between collagen bundles. And it's at the periphery one frequently sees extravasated erythrocytes, siderophages, and an infiltrate of lymphocytes. So targetoid hemosiderotic hemangioma. Sometimes it can be quite difficult to distinguish these from patch gage stage Kaposi's. And again, HHV8 stain will help you because these are routinely negative for HHVA and the Kaposi's, of course, will always stain with an HHV8 stain. And we will close out our discussion with slide number 12, which is kind of a cool case to end on. And we have two pieces of tissue here. And if",
"med_umls_ids": "[[{'entity': 'Dilated', 'concept_id': 'C0700124', 'confidence': 0.9999999403953552}, {'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}], [{'entity': 'Papillary projections', 'concept_id': 'C0016538', 'confidence': 0.7451471090316772}, {'entity': 'lumina', 'concept_id': 'C0524462', 'confidence': 0.845600426197052}], [{'entity': 'Enlarged endothelial cells', 'concept_id': 'C0423263', 'confidence': 0.7785332202911377}], [{'entity': 'Compressed vascular channels', 'concept_id': 'C1336948', 'confidence': 0.5993747711181641}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'bundles', 'concept_id': 'C3658308', 'confidence': 0.8706014752388}], [{'entity': 'Extravasated', 'concept_id': 'C0015376', 'confidence': 0.868863582611084}, {'entity': 'erythrocytes', 'concept_id': 'C0014772', 'confidence': 1.0}, {'entity': 'siderophages', 'concept_id': 'C1136253', 'confidence': 0.7251443266868591}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}], [{'entity': 'Targetoid hemosiderotic hemangioma', 'concept_id': 'C0346076', 'confidence': 0.9999999403953552}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'targetoid hemosiderotic hemangioma', 'concept_id': 'C0346076', 'confidence': 0.9999999403953552}, {'entity': \"patch stage Kaposi's\", 'concept_id': 'C0280201', 'confidence': 0.7629613280296326}], [{'entity': 'HHV8', 'concept_id': 'C0036220', 'confidence': 1.0}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_374",
"caption_rating": "8"
},
{
"": "1008440",
"caption": "Presence of melanophages with variable size and shape.",
"image_path": "8S4LeiO6Bbk_image_a620e8c7-c69d-45dd-a59c-1c1cbe14f75f.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Melanin granules within melanophages', 'Extravasated erythrocytes', 'Increased melanin in the basilar keratinocytes.', 'Melanin granules within melanophages', 'Extravasated erythrocytes', 'Increased melanin in the basilar keratinocytes.']",
"noisy_text": " or the melanophages is variable in size and shape. Now look at the melanin granules within this melanophage, and you can see that they're much more uniform in size and shape. Now look at the melanin granules within this melanophage, and you can see that they're much more uniform in size than the hemocentauric pigment in the centaurifages. It also tends to be a little bit darker staining, but sometimes it can be very difficult, tinctorially, depending upon the staining quality, to use color to distinguish the two, better to use size and context clues. Also note here we don't have any extravasated erythrocytes here, so much more likely to be melanin, and there's an increased melanin in the basilar keratinocytes. Getting back to the case, thin epidermis, bacular",
"corrected_text": " or the melanophages is variable in size and shape. Now look at the melanin granules within this melanophage, and you can see that they're much more uniform in size and shape. Now look at the melanin granules within this melanophage, and you can see that they're much more uniform in size than the hemosiderin pigment in the centroblasts. It also tends to be a little bit darker staining, but sometimes it can be very difficult, tinctorially, depending upon the staining quality, to use color to distinguish the two, better to use size and context clues. Also note here we don't have any extravasated erythrocytes here, so much more likely to be melanin, and there's an increased melanin in the basilar keratinocytes. Getting back to the case, thin epidermis, bacular",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'melanophages', 'concept_id': 'C3280463', 'confidence': 0.9375340938568115}, {'entity': 'variable size', 'concept_id': 'C1866144', 'confidence': 0.8559831976890564}, {'entity': 'shape', 'concept_id': 'C0332479', 'confidence': 1.0}], [{'entity': 'Melanin granules', 'concept_id': 'C0230692', 'confidence': 0.9174172878265381}, {'entity': 'melanophages', 'concept_id': 'C3280463', 'confidence': 0.9375340938568115}, {'entity': 'uniform', 'concept_id': 'C0205375', 'confidence': 1.0}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'shape', 'concept_id': 'C0332479', 'confidence': 1.0}, {'entity': 'hemosiderin', 'concept_id': 'C0019113', 'confidence': 1.0}, {'entity': 'pigment', 'concept_id': 'C0031911', 'confidence': 1.0}, {'entity': 'centroblasts', 'concept_id': 'C1517735', 'confidence': 0.8281925320625305}], [{'entity': 'Increased', 'concept_id': 'C0205217', 'confidence': 1.0}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}, {'entity': 'basilar keratinocytes', 'concept_id': 'C0022567', 'confidence': 0.803361713886261}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_375",
"caption_rating": "8"
},
{
"": "1005576",
"caption": "Cribriform glands at the edge of a core are usually high-grade tumors.",
"image_path": "iklRyY1nBIE_image_ff372154-847a-4eee-acf2-1410e6eae2e6.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['intraductal carcinoma', 'cribriform glands', 'basal cells']",
"noisy_text": " And I'll demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues, it's very important to make that point clear. So this is the corresponding to the case I showed you. So let me just show you a couple more examples of introductal carcinoma of the prostate. So this case, this one looks a little different. You don't have, I mean, looking at the HNE, you may assume all this is invasive. But you'll probably be surprised when you see the corresponding pain cocktail. What you can see here are cribriform glands. Again, it's a busy, busy core, lots of glands. And when you see tumor cells or glands at the edge of a core, at the edge of a core like this, that's usually bats. And usually high-grade tumors that do that. But when you see what we're seeing here, a lot of cribriform glands. And if you go a bit closer, you can see a hint of basal cells around most of them. So we'll",
"corrected_text": " And I'demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues, it's very important to make that point clear. So this is the corresponding to the case I showed you. So let me just show you a couple more examples of introductal carcinoma of the prostate. So this case, this one looks a little different. You don't have, I mean, looking at the HNE, you may assume all this is invasive. But you'll probably be surprised when you see the corresponding pain cocktail. What you can see here are cribriform glands. Again, it's a busy, busy core, lots of glands. And when you see tumor cells or glands at the edge of a core, at the edge of a core like this, that's usually bats. And usually high-grade tumors that do that. But when you see what we're seeing here, a lot of cribriform glands. And if you go a bit closer, you can see a hint of basal cells around most of them. So we'll",
"med_umls_ids": "[[{'entity': 'Intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'associated with', 'concept_id': 'C0332281', 'confidence': 1.0}, {'entity': 'invasive cancer', 'concept_id': 'C0677898', 'confidence': 1.0}], [{'entity': 'Cribriform glands', 'concept_id': 'C1285092', 'confidence': 0.6162902116775513}, {'entity': 'edge', 'concept_id': 'C0205154', 'confidence': 1.0}, {'entity': 'core', 'concept_id': 'C0444669', 'confidence': 0.9999999403953552}, {'entity': 'high-grade tumors', 'concept_id': 'C0027651', 'confidence': 0.5436328053474426}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'basal cells', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'cribriform glands', 'concept_id': 'C1285092', 'confidence': 0.6162902116775513}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_376",
"caption_rating": "8"
},
{
"": "1006950",
"caption": "Spongiosis is present in sep-derm, indicating seborrheic dermatitis.",
"image_path": "udoW6VSqsm4_image_10f1e59c-526f-45f9-9d88-cc22c8463445.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " Now what's this pattern, what are we looking at right here? What's the histologic reaction pattern? Oh, it's the spongiosis. Some spongiosis. So you can see some spongiosis in sep-derm, just like that case last night that you guys presented had spongiosis and psoriasiform hyperplasia. You can see some spongiosis in sep-derm, so it doesn't mean that they have allergic contact dermatitis or anything like that. So this is pretty good for sep-derm. If you want to say, well, there's a little more psoriasiform hyperplasia than usual there for seiboceriasis, try to avoid the term seiboceriasis because it's kind of a wastebasket a little bit. It doesn't commit to one diagnosis or the other. So I would favor sep-derm here more so than psoriasis, but it's a little more psoriasiform than usual. These are the clinical photos. You guys all know all about sep-derms.",
"corrected_text": " Now what's this pattern, what are we looking at right here? What's the histologic reaction pattern? Oh, it's the spongiosis. Some spongiosis. So you can see some spongiosis in sep-derm, just like that case last night that you guys presented had spongiosis and psoriasiform hyperplasia. You can see some spongiosis in sep-derm, so it doesn't mean that they have allergic contact dermatitis or anything like that. So this is pretty good for sep-derm. If you want to say, well, there's a little more psoriasiform hyperplasia than usual there for seborrheic dermatitis, try to avoid the term seborrheic dermatitis because it's kind of a wastebasket a little bit. It doesn't commit to one diagnosis or the other. So I would favor sep-derm here more so than psoriasis, but it's a little more psoriasiform than usual. These are the clinical photos. You guys all know all about sep-derms.",
"med_umls_ids": "[[{'entity': 'Spongiosis', 'concept_id': 'C0702120', 'confidence': 1.0}, {'entity': 'histologic reaction', 'concept_id': 'C0205462', 'confidence': 0.8118124008178711}], [{'entity': 'Spongiosis', 'concept_id': 'C0702120', 'confidence': 1.0}, {'entity': 'seborrheic dermatitis', 'concept_id': 'C0036508', 'confidence': 1.0}], [{'entity': 'Psoriasiform hyperplasia', 'concept_id': 'C3281279', 'confidence': 0.9999999403953552}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'seborrheic dermatitis', 'concept_id': 'C0036508', 'confidence': 1.0}, {'entity': 'psoriasis', 'concept_id': 'C0033860', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_377",
"caption_rating": "8"
},
{
"": "1007967",
"caption": "Absence of plasma cells within the infiltrate helps to differentiate this condition from Kaposi sarcoma.",
"image_path": "8S4LeiO6Bbk_image_399c0607-b6b7-42ed-bfd8-639e0006c57b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['papillary projections', 'extravasated erythrocytes', 'dilated vessels', 'enlarged endothelial cells', 'collagen bundles', 'pre-existing vascular spaces', 'papillary projections', 'extravasated erythrocytes', 'dilated vessels', 'enlarged endothelial cells', 'collagen bundles', 'pre-existing vascular spaces']",
"noisy_text": " into the limina. If you look around, you can see these papillary projections. There are a few extravasated erythrocytes present within the stroma. So clearly, we've got this vascular neoplasma here with these dilated endothelial line spaces, but it's got kind of a bifasic pattern. Centrally, we've got these dilated vessels, but peripheral and beneath that zone, the vessels are somewhat more compressed. They're still lined by some of the plump endothelial cells. And in these various where the vessels are compressed, they kind of appear to dissect between collagen bundles. We even have a little bit of a promontory sign here where we've got these vessels surrounding pre-existing vascular spaces. But unlike the neovascular spaces that we see in Kaposi's sarcoma, the endothelial cells here are a little more plump, and we don't have plasma cells within the infiltrate. And plasma cells within the infiltrate can be very useful in discriminating between this condition and Kaposi's sarcoma. In this particular case, also the HHV8 stain was a negative, which",
"corrected_text": " into the limina. If you look around, you can see these papillary projections. There are a few extravasated erythrocytes present within the stroma. So clearly, we've got this vascular neoplasm here with these dilated endothelial line spaces, but it's got kind of a biphasic pattern. Centrally, we've got these dilated vessels, but peripheral and beneath that zone, the vessels are somewhat more compressed. They're still lined by some of the enlarged endothelial cells. And in these various where the vessels are compressed, they kind of appear to dissect between collagen bundles. We even have a little bit of a promontory sign here where we've got these vessels surrounding pre-existing vascular spaces. But unlike the neovascularization that we see in Kaposi's sarcoma, the endothelial cells here are a little more plump, and we don't have plasma cells within the infiltrate. And plasma cells within the infiltrate can be very useful in discriminating between this condition and Kaposi's sarcoma. In this particular case, also the HHV8 stain was a negative, which",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'vascular neoplasm', 'concept_id': 'C0027668', 'confidence': 1.0}, {'entity': 'dilated endothelial line spaces', 'concept_id': 'C0014257', 'confidence': 0.6450937390327454}, {'entity': 'biphasic pattern', 'concept_id': 'C1332555', 'confidence': 1.0}], [{'entity': 'Vessels', 'concept_id': 'C0005847', 'confidence': 1.0}, {'entity': 'peripheral', 'concept_id': 'C0205100', 'confidence': 1.0}, {'entity': 'central zone', 'concept_id': 'C0458698', 'confidence': 1.0}], [{'entity': 'Endothelial cells', 'concept_id': 'C0225336', 'confidence': 1.0}, {'entity': 'enlarged', 'concept_id': 'C0442800', 'confidence': 1.0}, {'entity': 'plump', 'concept_id': 'C1836543', 'confidence': 0.7694027423858643}], [{'entity': 'Absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'differentiate', 'concept_id': 'C0205615', 'confidence': 0.9999998807907104}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'Kaposi sarcoma', 'concept_id': 'C0036220', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "758.0",
"width": "1920.0",
"id": "test_378",
"caption_rating": "8"
},
{
"": "1007219",
"caption": "Presence of heavily pigmented melanophages in the dermis.",
"image_path": "8S4LeiO6Bbk_image_38e60f68-290e-4146-add5-b6c842bcc610.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['dendritic', 'spindle-shaped', 'heavily pigmented melanophages', 'dendritic', 'spindle-shaped', 'intersecting vessels', 'combined melanocytic nevus', 'blue nevus']",
"noisy_text": " pairs. In the central portion of the specimen, you can see that the dermis is a little more sclerotic. And we've got the presence of separately heavily pigmented melanovagias. And then if we look at our top piece of tissue, again, we have the more banal appearing melanocytes out of the periphery. And centrally, we've got embedded within a sclerotic stroma a second distinct morphologic population of melanocytes. Some of these are dendritic, others have spindled or fusiform-shaped nuclei. They're arranged in short, intersecting vascals. And in between the dendritic and spindled melanocytes, we have very heavily pigmented melanovagias, all set in a sclerotic stroma. So basically, we have here a combined melanocytic nevus, one that has features of both a common or banal nevus and a blue nevus. And this",
"corrected_text": " pairs. In the central portion of the specimen, you can see that the dermis is a little more sclerotic. And we've got the presence of separately heavily pigmented melanovagias. And then if we look at our top piece of tissue, again, we have the more banal appearing melanocytes out of the periphery. And centrally, we've got embedded within a sclerotic stroma a second distinct morphologic population of melanocytes. Some of these are dendritic, others have spindle-shaped or fusiform-shaped cells. They're arranged in short, intersecting vessels. And in between the dendritic and spindle-shaped melanocytes, we have very heavily pigmented melanovagias, all set in a sclerotic stroma. So basically, we have here a combined melanocytic nevus, one that has features of both a common or banal nevus and a blue nevus. And this",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'heavily', 'concept_id': 'C0337678', 'confidence': 0.6902515292167664}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'melanophages', 'concept_id': 'C3280463', 'confidence': 0.9375340938568115}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}], [{'entity': 'morphologic populations', 'concept_id': 'C0032659', 'confidence': 0.6858205199241638}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'dendritic', 'concept_id': 'C0011305', 'confidence': 1.0}, {'entity': 'spindle-shaped', 'concept_id': 'C4230397', 'confidence': 0.9035798907279968}, {'entity': 'fusiform-shaped', 'concept_id': 'C0332493', 'confidence': 0.6468937397003174}], [{'entity': 'Arranged', 'concept_id': 'C1546854', 'confidence': 1.0}, {'entity': 'short', 'concept_id': 'C1282927', 'confidence': 1.0}, {'entity': 'intersecting vessels', 'concept_id': 'C0005847', 'confidence': 0.7007781863212585}], [{'entity': 'Combined', 'concept_id': 'C0205195', 'confidence': 1.0}, {'entity': 'melanocytic nevus', 'concept_id': 'C0027962', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'benign nevus', 'concept_id': 'C1456781', 'confidence': 1.0}, {'entity': 'blue nevus', 'concept_id': 'C0206736', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_379",
"caption_rating": "9"
},
{
"": "1007264",
"caption": "Presence of eosinophils and band interrupts inflammatory cells and capillaries.",
"image_path": "sDFjOtMAYrk_image_1084161e-7caa-402a-825a-a07d77549d1b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['Thick and irregular band with feet-like projections into the lamina propria.']",
"noisy_text": " and some eos. And what else? Yeah, exactly. So the band interrupts inflammatory cells and capillaries, and it's not just the thickness of the band that really catches your eyes, the irregularity of it. So you don't have a thin smooth line anymore. It's just, you know, thick and irregular, just just throwing like feet down into the, into the lamina appropriate. There are also a few lymphocytes in the epithelium, but that's not the main finding. The other thing you might find in some of these is some degree of active inflammation. And let",
"corrected_text": " and some eos. And what else? Yeah, exactly. So the band interrupts inflammatory cells and capillaries, and it's not just the thickness of the band that really catches your eyes, the irregularity of it. So you don't have a thin smooth line anymore. It's just, you know, thick and irregular, just just throwing like feet down into the, into the lamina appropriate. There are also a few lymphocytes in the epithelium, but that's not the main finding. The other thing you might find in some of these is some degree of active inflammation. And let",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'band', 'concept_id': 'C0175723', 'confidence': 1.0}, {'entity': 'inflammatory cells', 'concept_id': 'C0440752', 'confidence': 1.0}, {'entity': 'capillaries', 'concept_id': 'C0006901', 'confidence': 0.9999998807907104}], [{'entity': 'Thick', 'concept_id': 'C1280412', 'confidence': 1.0}, {'entity': 'irregular', 'concept_id': 'C0205271', 'confidence': 1.0}, {'entity': 'projections', 'concept_id': 'C0016538', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'active', 'concept_id': 'C0205177', 'confidence': 1.0}, {'entity': 'inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_380",
"caption_rating": "7"
},
{
"": "1006043",
"caption": "The morphology of the aggregations suggests intravascular epithelial metastasis, which could be from a metastatic salivary gland cancer or a squamous cancer like salivary duct cancer.",
"image_path": "LlPaENuqzVQ_image_9a080b83-e0b9-4e50-b86b-6ea9616c4c43.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['intravascular epithelial metastasis', 'intravascular epithelial metastasis']",
"noisy_text": " the cells you saw there? Probably not. Now, we probably would have just called it intravascular metastasis. I don't think I would have suggested lymphoma just because of the morphology of these aggregations here. That looks more epithelial to me, but no, you'd want to get history. This could be maybe a metastatic salivary gland cancer or even possibly the weird squamous cancer, salivary duct cancer. So all you can say is it looks like an intravascular epithelial metastasis and probably wouldn't really go much further there unless you had a history of it. So, yeah, no, we don't branch out on the limb and just say, ah, it's obviously metastatic breast cancer or something like this. That wouldn't be appropriate. Do you usually, like, do a panel of stains on it if you got something like this just to see if there's, like, any info you can give them or no? The first",
"corrected_text": " the cells you saw there? Probably not. Now, we probably would have just called it intravascular metastasis. I don't think I would have suggested lymphoma just because of the morphology of these aggregations here. That looks more epithelial to me, but no, you'd want to get history. This could be maybe a metastatic salivary gland cancer or even possibly the weird squamous cancer, salivary duct cancer. So all you can say is it looks like an intravascular epithelial metastasis and probably wouldn't really go much further there unless you had a history of it. So, yeah, no, we don't branch out on the limb and just say, ah, it's obviously metastatic breast cancer or something like this. That wouldn't be appropriate. Do you usually, like, do a panel of stains on it if you got something like this just to see if there's, like, any info you can give them or no? The first",
"med_umls_ids": "[[{'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}, {'entity': 'aggregations', 'concept_id': 'C0332621', 'confidence': 0.9210782051086426}, {'entity': 'intravascular', 'concept_id': 'C0442123', 'confidence': 1.0}, {'entity': 'metastatic salivary gland cancer', 'concept_id': 'C0278992', 'confidence': 1.0}, {'entity': 'squamous cancer', 'concept_id': 'C0007137', 'confidence': 0.9055708050727844}, {'entity': 'salivary duct cancer', 'concept_id': 'C0282582', 'confidence': 0.8532246351242065}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_381",
"caption_rating": "9"
},
{
"": "1006637",
"caption": "Histopathology shows predominantly pink fibrous component and a lesser bluish myxoid component, consistent with fibromyxoid tumors.",
"image_path": "QDb68_G1HR4_image_c41b7d98-fbc3-4d8e-b5e7-b34a367c9792.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Predominantly pink fibrous component and a lesser myxoid bluish component.']",
"noisy_text": " background fades out kind of quickly on H and E but the predominant color here is pink and I think this is one easy way to help remember this, fibromyxoid. The name says fibro before the word myxo. So the fibro is the pink part, the myxoid is the bluish pale part and these tumors usually not always but usually have a predominantly fibrous pink component and a lesser myxoid bluish component so it looks more pink. The way I also remember it is some of the original tumors that Dr. Evans described were misdiagnosed originally as either fibroma which is a good example of why it's dangerous to call",
"corrected_text": " background fades out kind of quickly on H and E but the predominant color here is pink and I think this is one easy way to help remember this, fibromyxoid. The name says fibro before the word myxoid. So the fibro is the pink part, the myxoid is the bluish pale part and these tumors usually not always but usually have a predominantly fibrous pink component and a lesser myxoid bluish component so it looks more pink. The way I also remember it is some of the original tumors that Dr. Evans described were misdiagnosed originally as either fibroma which is a good example of why it's dangerous to call",
"med_umls_ids": "[[{'entity': 'Histopathology', 'concept_id': 'C0243140', 'confidence': 1.0}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}, {'entity': 'consistent with', 'concept_id': 'C0332290', 'confidence': 1.0}, {'entity': 'fibromyxoid tumors', 'concept_id': 'C0205766', 'confidence': 0.9253939986228943}], [{'entity': 'Fibro', 'concept_id': 'C0016053', 'confidence': 0.9999999403953552}, {'entity': 'pink', 'concept_id': 'C0332585', 'confidence': 1.0}, {'entity': 'myxoid', 'concept_id': 'C0205295', 'confidence': 1.0}, {'entity': 'bluish pale part', 'concept_id': 'C0392768', 'confidence': 0.6970505118370056}], [{'entity': 'original', 'concept_id': 'C0205313', 'confidence': 1.0}, {'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'misdiagnosed', 'concept_id': 'C0679838', 'confidence': 0.896425724029541}, {'entity': 'fibroma', 'concept_id': 'C0016045', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_382",
"caption_rating": "8"
},
{
"": "1004481",
"caption": "Increased reticuline in gastric mucosa is observed.",
"image_path": "r7OA0Trj5hQ_image_4a7224df-be04-4c7f-95eb-7144de15a124.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['fibrosis in the lamina propria']",
"noisy_text": " Whereas here, it's involving more endothelium. This is a special strain, gastric biopsy again. You see a lot of macrophages with the pink stuff. This is a AFB strain. Whenever you see a lot of pink stuff in the lamina propria within the macrophages, think of mycobacterium, AVM, intracellular. Then now, we have to assess the fibrosis in the lamina propria. Again, fibrosis is one of the chronicity criteria. This is normal glands, whereas here, gastric mucosa is the increased reticuline rich. Another thing you have to remember, reticuline strain, you have",
"corrected_text": " Whereas here, it's involving more endothelium. This is a special strain, gastric biopsy again. You see a lot of macrophages with the pink stuff. This is a AFB strain. Whenever you see a lot of pink stuff in the lamina propria within the macrophages, think of mycobacterium, AVM, intracellular. Then now, we have to assess the fibrosis in the lamina propria. Again, fibrosis is one of the chronicity criteria. This is normal glands, whereas here, gastric mucosa is the increased reticuline rich. Another thing you have to remember, reticulin stain, you have",
"med_umls_ids": "[[{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'involvement', 'concept_id': 'C1314939', 'confidence': 1.0}, {'entity': 'endothelium', 'concept_id': 'C0014257', 'confidence': 0.9999998807907104}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'macrophages', 'concept_id': 'C0024432', 'confidence': 1.0}, {'entity': 'pink stuff', 'concept_id': 'C0332585', 'confidence': 0.5879191756248474}, {'entity': 'AFB', 'concept_id': 'C0483226', 'confidence': 1.0}, {'entity': 'strain', 'concept_id': 'C0080194', 'confidence': 1.0}, {'entity': 'mycobacterium infection', 'concept_id': 'C0026918', 'confidence': 1.0}], [{'entity': 'Assessment', 'concept_id': 'C0031809', 'confidence': 1.0}, {'entity': 'fibrosis', 'concept_id': 'C0016059', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'chronicity', 'concept_id': 'C0547045', 'confidence': 1.0}], [{'entity': 'Increased', 'concept_id': 'C0205217', 'confidence': 1.0}, {'entity': 'reticuline', 'concept_id': 'C0073098', 'confidence': 1.0}, {'entity': 'gastric mucosa', 'concept_id': 'C0017136', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_383",
"caption_rating": "7"
},
{
"": "1007441",
"caption": "The patient was treated for sarcoidosis and subsequent biopsies showed no more granulomas.",
"image_path": "sDFjOtMAYrk_image_64ecfd50-c3b0-487d-b33a-10de6f769850.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['uveitis with characteristic features', 'granulomas in sarcoidosis and Crohn\u2019s disease', 'uveitis with characteristic features', 'granulomas in sarcoidosis and Crohn\u2019s disease']",
"noisy_text": " patient had sarcoid. So I said, this is probably not IBD, clinicians came down, we want to look at the biopsy, of course. It turns out that they went back and talked to the patient. The patient has a history of uveitis with characteristic features that were good for sarcoidosis. Nobody knew about they treated the patient for sarcoid, re-biopsied the patient. And he was fine. There were no more granulomas on multiple repeat biopsies. And now compare those grannies with the grannies in Crohn's. So here's a giant cell right there, but there was a better one right there. So they're like kind of",
"corrected_text": " patient had sarcoid. So I said, this is probably not IBD, clinicians came down, we want to look at the biopsy, of course. It turns out that they went back and talked to the patient. The patient has a history of uveitis with characteristic features that were good for sarcoidosis. Nobody knew about they treated the patient for sarcoid, re-biopsied the patient. And he was fine. There were no more granulomas on multiple repeat biopsies. And now compare those grannies with the grannies in Crohn's. So here's a giant cell right there, but there was a better one right there. So they're like kind of",
"med_umls_ids": "[[{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'suspected', 'concept_id': 'C0332147', 'confidence': 1.0}, {'entity': 'IBD', 'concept_id': 'C0021390', 'confidence': 1.0}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'history', 'concept_id': 'C0019664', 'confidence': 1.0}, {'entity': 'uveitis', 'concept_id': 'C0042164', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'treated', 'concept_id': 'C1522326', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'biopsies', 'concept_id': 'C0005558', 'confidence': 1.0}, {'entity': 'granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}], [{'entity': 'Comparison', 'concept_id': 'C1707455', 'confidence': 1.0}, {'entity': 'granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'Crohn\u2019s disease', 'concept_id': 'C0010346', 'confidence': 0.8916962146759033}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_384",
"caption_rating": "8"
},
{
"": "1004598",
"caption": "Presence of fat microcysts and membranous lipodystrophy.",
"image_path": "hoV-JkD6Wb0_image_35209858-1960-43a4-b29d-6d19d87470a1.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['septal panniculitis', 'lobular panniculitis', 'distortion of architecture', 'fat microcysts', 'membranous lipodystrophy', 'septal panniculitis', 'lobular panniculitis', 'distortion of architecture', 'fat microcysts', 'membranous lipodystrophy']",
"noisy_text": " inflammation. In this particular instance, we have a rip-roaring paniculitis here. We have a lobular paniculitis. If you take a look at the fat here, there's total distortion of the architecture, and this is barely discernible as subcutaneous tissue, but there's not a lot of inflammation. There aren't many viable adipocytes left here. A lot of the adipocytes have kind of ruptured and fused, and so we've got these large fat microcysts, and if we look at the periphery of the fat microcyst, we've got this lipomembranous change, this kind of arabesque-type fibular material out at the",
"corrected_text": " inflammation. In this particular instance, we have a septal panniculitis here. We have a lobular panniculitis. If you take a look at the fat here, there's total distortion of the architecture, and this is barely discernible as subcutaneous tissue, but there's not a lot of inflammation. There aren't many viable adipocytes left here. A lot of the adipocytes have kind of ruptured and fused, and so we've got these large fat microcysts, and if we look at the periphery of the fat microcyst, we've got this membranous lipodystrophy, this kind of arabesque-type fibular material out at the",
"med_umls_ids": "[[{'entity': 'Septal', 'concept_id': 'C0442004', 'confidence': 0.9999999403953552}, {'entity': 'lobular panniculitis', 'concept_id': 'C0263012', 'confidence': 1.0}, {'entity': 'distortion', 'concept_id': 'C0332482', 'confidence': 1.0}, {'entity': 'subcutaneous tissue', 'concept_id': 'C0222331', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'fat microcysts', 'concept_id': 'C1513269', 'confidence': 0.871767520904541}, {'entity': 'membranous lipodystrophy', 'concept_id': 'C0406599', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_385",
"caption_rating": "8"
},
{
"": "1008086",
"caption": "Too many melanocytes in the matrix are highly suspicious for melanoma in situ.",
"image_path": "8S4LeiO6Bbk_image_525701b0-e1bc-4c80-8310-ec56f677f9eb.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Presence of several melanocytes', 'too many melanocytes']",
"noisy_text": " examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matricle epithelium in the matricle layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that being said, we'll go ahead and move on to slide number two, which was a melanin A or Mk1 immunohistochemical stain of this same piece of tissue. Underneath this bubble here we have our control. This is",
"corrected_text": " examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matrix epithelium in the matrix layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that being said, we'll go ahead and move on to slide number two, which was a melanin A or Mk1 immunohistochemical stain of this same piece of tissue. Underneath this bubble here we have our control. This is",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'nests', 'concept_id': 'C0035253', 'confidence': 0.7275967001914978}, {'entity': 'confluence', 'concept_id': 'C0226863', 'confidence': 0.857487678527832}, {'entity': 'solitary units', 'concept_id': 'C0205171', 'confidence': 0.7227572798728943}, {'entity': 'base', 'concept_id': 'C0002055', 'confidence': 1.0}, {'entity': 'matrix epithelium', 'concept_id': 'C0014609', 'confidence': 0.7584323883056641}, {'entity': 'matrix layer', 'concept_id': 'C0331858', 'confidence': 0.71736741065979}, {'entity': 'basal layer', 'concept_id': 'C0221925', 'confidence': 1.0}, {'entity': 'matrix', 'concept_id': 'C0331858', 'confidence': 1.0}, {'entity': 'upper portions', 'concept_id': 'C0449719', 'confidence': 0.6251541972160339}, {'entity': 'matrix', 'concept_id': 'C0331858', 'confidence': 1.0}, {'entity': 'pagetoid', 'concept_id': 'C1518847', 'confidence': 0.8801172375679016}, {'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}], [{'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'matrix', 'concept_id': 'C0331858', 'confidence': 1.0}, {'entity': 'suspicious', 'concept_id': 'C0750493', 'confidence': 1.0}, {'entity': 'melanoma', 'concept_id': 'C0025202', 'confidence': 1.0}, {'entity': 'in situ', 'concept_id': 'C0444498', 'confidence': 0.9999999403953552}]]",
"magnification": "1.0",
"height": "758.0",
"width": "1920.0",
"id": "test_386",
"caption_rating": "8"
},
{
"": "1006850",
"caption": "The diagnosis in this case is a rudimentary supernumerary digit.",
"image_path": "8S4LeiO6Bbk_image_76bedbf1-de38-4994-8b90-f18fe5735913.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['dome-shaped papule', 'acral site', 'thick stratum corneum', 'absence of hair follicles', 'fibrovascular core', 'nerve fascicles', 'spindle-shaped cells', 'S100', 'SOX10', 'rudimentary supernumerary digit']",
"noisy_text": " we've got a dome-shaped papule and that the biopsy is from an acral site. Notice that we've got a very very thick stratum corneum and a marked to virtual absence of hair follicles within the specimen. We do have kind of this fibrovascular core and of course in the center of the fibrovascular core here we've got several well-defined nerve fascicles and the spindled cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions",
"corrected_text": " we've got a dome-shaped papule and that the biopsy is from an acral site. Notice that we've got a very very thick stratum corneum and a marked to virtual absence of hair follicles within the specimen. We do have kind of this fibrovascular core and of course in the center of the fibrovascular core here we've got several well-defined nerve fascicles and the spindle cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions",
"med_umls_ids": "[[{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'acral site', 'concept_id': 'C0439746', 'confidence': 0.717435359954834}, {'entity': 'dome-shaped papule', 'concept_id': 'C1711316', 'confidence': 0.752353847026825}], [{'entity': 'specimen', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'stratum corneum', 'concept_id': 'C0221921', 'confidence': 1.0}, {'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'hair follicles', 'concept_id': 'C0221971', 'confidence': 0.9999998807907104}], [{'entity': 'fibrovascular', 'concept_id': 'C0392759', 'confidence': 1.0}, {'entity': 'nerve fascicles', 'concept_id': 'C1185741', 'confidence': 0.8332967758178711}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'S100', 'concept_id': 'C3273837', 'confidence': 1.0}, {'entity': 'SOX10', 'concept_id': 'C1420317', 'confidence': 0.9999998807907104}, {'entity': 'neural tumor', 'concept_id': 'C1334956', 'confidence': 1.0}], [{'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'rudimentary supernumerary digit', 'concept_id': 'C0152427', 'confidence': 0.8142021894454956}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_387",
"caption_rating": "8"
},
{
"": "1005753",
"caption": "Description of a segment with a lamina propria that is pretty devoid of inflammatory cells.",
"image_path": "sDFjOtMAYrk_image_0372a472-d9ea-41fa-aabd-99bb51529283.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['lamina propria', 'inflammatory cells', 'eosinophils', 'lymphocytes', 'plasma cells', 'basement membrane', 'lamina propria', 'inflammatory cells', 'eosinophils', 'lymphocytes', 'plasma cells', 'basement membrane']",
"noisy_text": " segment and shows a lamina propria pretty devoid of... You see a couple of inflammatory cells here and there, but not really a lot in the way of lymphocytes, plasma cells, and actually eos are rare. But when you get biopsies, and I'm sorry I didn't bring one from... That was on the left. If you used to have something from the right, your lamina propria is typically busier, and I allow for quite a few eosinophils, lymphocytes, and plasma cells. The other thing that you want to keep in mind is... Let me just go back to the H and E for a second. The basement membrane, I will",
"corrected_text": " segment and shows a lamina propria pretty devoid of... You see a couple of inflammatory cells here and there, but not really a lot in the way of lymphocytes, plasma cells, and actually eos are rare. But when you get biopsies, and I'm sorry I didn't bring one from... That was on the left. If you used to have something from the right, your lamina propria is typically busier, and I allow for quite a few eosinophils, lymphocytes, and plasma cells. The other thing that you want to keep in mind is... Let me just go back to the H and E for a second. The basement membrane, I will",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'segment', 'concept_id': 'C0441635', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'inflammatory cells', 'concept_id': 'C0440752', 'confidence': 1.0}], [{'entity': 'Lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'right', 'concept_id': 'C0205090', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_388",
"caption_rating": "7"
},
{
"": "1008389",
"caption": "Inflammatory bowel disease can cause loss of organized tubular architecture and abnormal gland growth.",
"image_path": "sDFjOtMAYrk_image_e75718bc-5992-42ab-896c-edfd5f287d36.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "[]",
"noisy_text": " cytosis that includes some eosinophils. So, the other trich I like to use, and I heard this from Dr. Appelman one time when he was lecturing, and he described crypt architecture in cases with inflammatory bowel disease, you no longer have that nice organized test tubes in a rack kind of architecture. The glands start to look like anything they want to look like. Rabbits, monkeys, the face of Jesus, whatever, except for test tubes on a rack. And the other thing is, sometimes you'll see them instead of growing down, they'll grow sideways. So, that's very apparent, very abnormal. So, I would say this is great evidence of chronicity, good architectural distortion. What other features besides architecture can you see in cases where there's some chronicity, albeit nonspecific findings? I mean, nothing is specific in chronic inflammatory colonic pathology,",
"corrected_text": " cytosis that includes some eosinophils. So, the other trich I like to use, and I heard this from Dr. Appelman one time when he was lecturing, and he described crypt architecture in cases with inflammatory bowel disease, you no longer have that nice organized tubular architecture. The glands start to look like anything they want to look like. Rabbits, monkeys, the face of Jesus, whatever, except for test tubes on a rack. And the other thing is, sometimes you'll see them instead of growing down, they'll grow sideways. So, that's very apparent, very abnormal. So, I would say this is great evidence of chronicity, good architectural distortion. What other features besides architecture can you see in cases where there's some chronicity, albeit nonspecific findings? I mean, nothing is specific in chronic inflammatory colonic pathology,",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'cytosis', 'concept_id': 'C0010843', 'confidence': 0.7890887260437012}], [{'entity': 'Inflammatory bowel disease', 'concept_id': 'C0021390', 'confidence': 1.0}, {'entity': 'loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'tubular', 'concept_id': 'C0151747', 'confidence': 1.0}, {'entity': 'architecture', 'concept_id': 'C0003737', 'confidence': 1.0}, {'entity': 'abnormal', 'concept_id': 'C0205161', 'confidence': 1.0}, {'entity': 'growth', 'concept_id': 'C0018270', 'confidence': 1.0}], [{'entity': 'Chronicity', 'concept_id': 'C0547045', 'confidence': 1.0}, {'entity': 'architectural distortion', 'concept_id': 'C2826609', 'confidence': 1.0}, {'entity': 'nonspecific', 'concept_id': 'C0750540', 'confidence': 1.0}, {'entity': 'findings', 'concept_id': 'C2607943', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_389",
"caption_rating": "8"
},
{
"": "1005426",
"caption": "Intraductal carcinoma of the prostate is associated with high-volume, high-grade invasive cancer.",
"image_path": "iklRyY1nBIE_image_7b67ec48-61e0-473a-93a7-4bd6a284a4cc.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['positive lymph node', 'intraductal carcinoma', 'invasive cancer', 'prognosis is poor', 'positive lymph node', 'intraductal carcinoma', 'invasive cancer', 'prognosis is poor']",
"noisy_text": " there's actually a positive lymph node right there, see? So you can see there's no introductal carcinoma here, because it's impossible for an introductal process to metastasize. So the point I'm trying to make is introductal carcinoma of the prostate is associated with high-volume, high-grade invasive cancer next door that does all those bad things. So that's the message I'm trying to pass across. So this is a very good example of introductal carcinoma of the prostate with associated high-grade, high-volume invasive cancer. So the prognosis is not good. And it's very, very important to document this. So on the nidocore biopsy, it's very important to document this.",
"corrected_text": " there's actually a positive lymph node right there, see? So you can see there's no intraductal carcinoma here, because it's impossible for an intracanalicular process to metastasize. So the point I'm trying to make is intraductal carcinoma of the prostate is associated with high-volume, high-grade invasive cancer next door that does all those bad things. So that's the message I'm trying to pass across. So this is a very good example of intraductal carcinoma of the prostate with associated high-grade, high-volume invasive cancer. So the prognosis is not good. And it's very, very important to document this. So on the needle core biopsy, it's very important to document this.",
"med_umls_ids": "[[{'entity': 'Positive lymph node', 'concept_id': 'C0746319', 'confidence': 1.0}, {'entity': 'invasive cancer', 'concept_id': 'C0677898', 'confidence': 1.0}, {'entity': 'associated with', 'concept_id': 'C0332281', 'confidence': 1.0}, {'entity': 'intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}], [{'entity': 'Intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'associated with', 'concept_id': 'C0332281', 'confidence': 1.0}, {'entity': 'high-volume', 'concept_id': 'C3494218', 'confidence': 0.8583465814590454}, {'entity': 'high-grade invasive cancer', 'concept_id': 'C1512433', 'confidence': 0.6872689723968506}], [{'entity': 'Prognosis', 'concept_id': 'C0033325', 'confidence': 1.0}, {'entity': 'poor', 'concept_id': 'C0032854', 'confidence': 1.0}, {'entity': 'document', 'concept_id': 'C1301746', 'confidence': 1.0}, {'entity': 'needle core biopsy', 'concept_id': 'C1289798', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_390",
"caption_rating": "9"
},
{
"": "1007432",
"caption": "Presence of eosinophils and intracryptal eosinophilic microapses in patients receiving radiation.",
"image_path": "sDFjOtMAYrk_image_f5e1c62e-602e-4f58-823f-8c8d482be39e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "[]",
"noisy_text": " they're receiving radiation, is a lot of eosinophils and even intracryptal eosinophilic microapses. You don't see a lot in the way of neutrophils. You may see some neutrophils in the cytoplasm of the nuclei, like intracellular intracytoplasmic neutrophils, but not really neutrophilic microapses. And the other thing you might see is intracytoplasmic vacuoles degenerating vacuoles. So, this is a good example of chemotherapy associated colitis, a mimic of inflammatory bowel disease. Oh, this is a good one. With that degree, the mild degree of architectural distortion is what's making me fall short of saying this is for sure IBD. So, I would be descriptive and I would say, you know,",
"corrected_text": " they're receiving radiation, is a lot of eosinophils and even intracryptal eosinophilic microapses. You don't see a lot in the way of neutrophils. You may see some neutrophils in the cytoplasm of the nuclei, like intracellular intracytoplasmic neutrophils, but not really neutrophilic microapses. And the other thing you might see is intracytoplasmic vacuoles degenerating vacuoles. So, this is a good example of chemotherapy associated colitis, a mimic of inflammatory bowel disease. Oh, this is a good one. With that degree, the mild degree of architectural distortion is what's making me fall short of saying this is for sure IBD. So, I would be descriptive and I would say, you know,",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'intracryptal', 'concept_id': 'C3315370', 'confidence': 0.626490592956543}, {'entity': 'microapses', 'concept_id': 'C0700712', 'confidence': 0.5626617074012756}, {'entity': 'patients', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'radiation', 'concept_id': 'C0034519', 'confidence': 1.0}], [{'entity': 'intracellular', 'concept_id': 'C0175996', 'confidence': 1.0}, {'entity': 'intracytoplasmic', 'concept_id': 'C0230649', 'confidence': 0.8670988082885742}, {'entity': 'neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'degenerating', 'concept_id': 'C0011164', 'confidence': 1.0}, {'entity': 'vacuoles', 'concept_id': 'C0042219', 'confidence': 1.0}], [{'entity': 'Chemotherapy', 'concept_id': 'C0013216', 'confidence': 1.0}, {'entity': 'colitis', 'concept_id': 'C0009319', 'confidence': 1.0}, {'entity': 'inflammatory bowel disease', 'concept_id': 'C0021390', 'confidence': 1.0}], [{'entity': 'Mild', 'concept_id': 'C1513302', 'confidence': 1.0}, {'entity': 'degree', 'concept_id': 'C0441889', 'confidence': 1.0}, {'entity': 'architectural distortion', 'concept_id': 'C2826609', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_391",
"caption_rating": "8"
},
{
"": "1005932",
"caption": "Papillary projections are frequently seen in the bottom piece of the tumor.",
"image_path": "8S4LeiO6Bbk_image_d45f4a7f-f27c-459c-980a-d6d5bc542879.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['dilated vascular channels', 'papillary projections', 'enlarged endothelial cells', 'compressed vascular channels', 'extravasated erythrocytes', 'dilated vascular channels', 'papillary projections', 'enlarged endothelial cells', 'compressed vascular channels', 'extravasated erythrocytes']",
"noisy_text": " which will slowly risk halt. These lesions will stain, frequently with CD34, but also are strongly positive for D240. So they probably are of lymphatic origin rather than vascular origin. What one looks for is a biphasic vascular tumor with this central area characterized by these dilated vascular channels. Let's look at the bottom piece, which frequently do contain these papillary projections, which protrude into the lumina, these plump endothelial cells, and then at the periphery, more compressed vascular channels, which dissect between collagen bundles. And it's at the periphery one frequently sees extravasated erythrocytes, siderophages, and",
"corrected_text": " which will slowly risk halt. These lesions will stain, frequently with CD34, but also are strongly positive for D240. So they probably are of lymphatic origin rather than vascular origin. What one looks for is a biphasic vascular tumor with this central area characterized by these dilated vascular channels. Let's look at the bottom piece, which frequently do contain these papillary projections, which protrude into the lumina, these plump endothelial cells, and then at the periphery, more compressed vascular channels, which dissect between collagen bundles. And it's at the periphery one frequently sees extravasated erythrocytes, siderophages, and",
"med_umls_ids": "[[{'entity': 'Lesions', 'concept_id': 'C0221198', 'confidence': 1.0}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'CD34', 'concept_id': 'C0054953', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'D240', 'concept_id': 'C3766973', 'confidence': 0.5323090553283691}, {'entity': 'lymphatic origin', 'concept_id': 'C0229889', 'confidence': 0.7706887125968933}, {'entity': 'vascular origin', 'concept_id': 'C0395959', 'confidence': 0.7819716334342957}], [{'entity': 'biphasic', 'concept_id': 'C0205184', 'confidence': 1.0}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'dilated', 'concept_id': 'C0700124', 'confidence': 0.9999999403953552}, {'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}, {'entity': 'central area', 'concept_id': 'C0929543', 'confidence': 0.8492603302001953}], [{'entity': 'Papillary projections', 'concept_id': 'C0016538', 'confidence': 0.7451471090316772}, {'entity': 'bottom piece', 'concept_id': 'C1511276', 'confidence': 0.722324788570404}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}], [{'entity': 'Enlarged endothelial cells', 'concept_id': 'C0423263', 'confidence': 0.7785332202911377}, {'entity': 'papillary projections', 'concept_id': 'C0016538', 'confidence': 0.7451471090316772}], [{'entity': 'Compressed vascular channels', 'concept_id': 'C1336948', 'confidence': 0.5993747711181641}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}], [{'entity': 'Extravasated', 'concept_id': 'C0015376', 'confidence': 0.868863582611084}, {'entity': 'erythrocytes', 'concept_id': 'C0014772', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_392",
"caption_rating": "7"
},
{
"": "1005779",
"caption": "DFSP is usually in the skin and rarely involves deep soft tissue.",
"image_path": "QDb68_G1HR4_image_eccb54ef-3bbb-47e2-b114-1e76f381358d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['whirling pattern']",
"noisy_text": " This one's not really showing that but some of them do, they have a lot of whirling pattern. So the two other things that keep in the differential here are perineurioma and also dermatofibrosarcoma protuberans, DFSP, which also has a tends to have a story form or whirled and swirled growth pattern and also has a translocation sarcoma, has very bland spindle cells. Okay, I guess I don't have any immunostains with me to show you today but just briefly the immunostains, most of the immunostains that we use for soft tissue tumors are negative most of the time in low-grade fibromyxoid sarcoma. CD34 is usually negative which is a pretty easy way to separate this from DFSP. The other thing is that low-grade fibromyxoid sarcoma usually is a relatively larger and deep, deep soft tissue below the fascia mass, although there are rare examples that are small and superficial and those seem to be more common in children. But DFSP is essentially always in the skin, the dermis or subcutaneous and rarely ever involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is",
"corrected_text": " This one's not really showing that but some of them do, they have a lot of whirling pattern. So the two other things that keep in the differential here are perineurioma and also dermatofibrosarcoma protuberans, DFSP, which also has a tends to have a story form or whirled and swirled growth pattern and also has a translocation sarcoma, has very bland spindle cells. Okay, I guess I don't have any immunostaining with me to show you today but just briefly the immunostaining, most of the immunostaining that we use for soft tissue tumors are negative most of the time in low-grade fibromyxoid sarcoma. CD34 is usually negative which is a pretty easy way to separate this from DFSP. The other thing is that low-grade fibromyxoid sarcoma usually is a relatively larger and deep, deep soft tissue below the fascia mass, although there are rare examples that are small and superficial and those seem to be more common in children. But DFSP is essentially always in the skin, the dermis or subcutaneous and rarely ever involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is",
"med_umls_ids": "[[{'entity': 'Whirling pattern', 'concept_id': 'C0449774', 'confidence': 0.6110570430755615}, {'entity': 'perineurioma', 'concept_id': 'C0751691', 'confidence': 0.9999999403953552}, {'entity': 'dermatofibrosarcoma protuberans', 'concept_id': 'C0206647', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}], [{'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}, {'entity': 'skin', 'concept_id': 'C0444099', 'confidence': 1.0}, {'entity': 'deep soft tissue', 'concept_id': 'C0225317', 'confidence': 0.7996832728385925}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_393",
"caption_rating": "7"
},
{
"": "1007265",
"caption": "Thick and irregular band with feet-like projections into the lamina propria.",
"image_path": "sDFjOtMAYrk_image_1084161e-7caa-402a-825a-a07d77549d1b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['Thick and irregular band with feet-like projections into the lamina propria.']",
"noisy_text": " and some eos. And what else? Yeah, exactly. So the band interrupts inflammatory cells and capillaries, and it's not just the thickness of the band that really catches your eyes, the irregularity of it. So you don't have a thin smooth line anymore. It's just, you know, thick and irregular, just just throwing like feet down into the, into the lamina appropriate. There are also a few lymphocytes in the epithelium, but that's not the main finding. The other thing you might find in some of these is some degree of active inflammation. And let",
"corrected_text": " and some eos. And what else? Yeah, exactly. So the band interrupts inflammatory cells and capillaries, and it's not just the thickness of the band that really catches your eyes, the irregularity of it. So you don't have a thin smooth line anymore. It's just, you know, thick and irregular, just just throwing like feet down into the, into the lamina appropriate. There are also a few lymphocytes in the epithelium, but that's not the main finding. The other thing you might find in some of these is some degree of active inflammation. And let",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'band', 'concept_id': 'C0175723', 'confidence': 1.0}, {'entity': 'inflammatory cells', 'concept_id': 'C0440752', 'confidence': 1.0}, {'entity': 'capillaries', 'concept_id': 'C0006901', 'confidence': 0.9999998807907104}], [{'entity': 'Thick', 'concept_id': 'C1280412', 'confidence': 1.0}, {'entity': 'irregular', 'concept_id': 'C0205271', 'confidence': 1.0}, {'entity': 'projections', 'concept_id': 'C0016538', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'active', 'concept_id': 'C0205177', 'confidence': 1.0}, {'entity': 'inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_394",
"caption_rating": "8"
},
{
"": "1006646",
"caption": "Discussion of a possible diagnosis of IBD based on the presence of pannate cell metaplasia and distortion associated with a lymphoid aggregate in the preserved lamina propria.",
"image_path": "sDFjOtMAYrk_image_72a31838-8594-4098-a6f2-28f55656f2df.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['distortion associated with a huge lymphoid aggregate', 'prominent lymphoid aggregates', 'pannate cell metaplasia', 'distortion associated with a huge lymphoid aggregate']",
"noisy_text": " discuss further down the road. And then the last differential is this. All right. So, Emilio, what would you say about the architecture in this case? Yeah. And then in some areas, there's a little bit of distortion, but what's the distortion associated with? Yeah, a huge lymphoid aggregate. So, this case, as you move along, you'll see a couple of prominent lymphoid aggregates there, here, in the backdrop of preserved lamina propria. So, and then, okay, it might be IBD, especially because there's pannate cell metaplasia, and this is from the rectum. You see the pannate cell metaplasia is showing well?",
"corrected_text": " discuss further down the road. And then the last differential is this. All right. So, Emilio, what would you say about the architecture in this case? Yeah. And then in some areas, there's a little bit of distortion, but what's the distortion associated with? Yeah, a huge lymphoid aggregate. So, this case, as you move along, you'll see a couple of prominent lymphoid aggregates there, here, in the backdrop of preserved lamina propria. So, and then, okay, it might be IBD, especially because there's pannate cell metaplasia, and this is from the rectum. You see the pannate cell metaplasia is showing well?",
"med_umls_ids": "[[{'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'IBD', 'concept_id': 'C0021390', 'confidence': 1.0}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'pannate cell', 'concept_id': 'C0007634', 'confidence': 0.5671628713607788}, {'entity': 'distortion', 'concept_id': 'C0332482', 'confidence': 1.0}, {'entity': 'associated with', 'concept_id': 'C0332281', 'confidence': 1.0}, {'entity': 'lymphoid', 'concept_id': 'C1518071', 'confidence': 1.0}, {'entity': 'aggregate', 'concept_id': 'C0205418', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_395",
"caption_rating": "8"
},
{
"": "1006547",
"caption": "Focal area of calcification can be seen in the tumor.",
"image_path": "PJX3uZ7fRn4_image_f749ca24-e5b0-46f3-ac60-273091bcb4e3.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gynecologic', 'Soft tissue', 'Hematopathology']",
"roi_text": "['vascular channels', 'chorionic villi', 'calcification', 'vascular channels', 'chorionic villi', 'calcification']",
"noisy_text": " This is a section from placenta which shows a large irregular area with proliferation of thin walled vascular channels of variable size towards the fetal surface of placenta. Smaller chorionic villi can be seen towards the maternal site. Higher magnification of the same showing large vascular channels in the chorion filled with blood. Still higher magnification showing intercommunicating slit-like vascular spaces in the mass. Focal area of calcification can be seen in the tumor. Still another area",
"corrected_text": " This is a section from placenta which shows a large irregular area with proliferation of thin walled vascular channels of variable size towards the fetal surface of placenta. smaller chorionic villi are not incorrect can be seen towards the maternal site. Higher magnification of the same showing large vascular channels in the chorion filled with blood. Still higher magnification showing intercommunicating slit-like vascular spaces in the mass. Focal area of calcification can be seen in the tumor. Still another area",
"med_umls_ids": "[[{'entity': 'Proliferation', 'concept_id': 'C0334094', 'confidence': 1.0}, {'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}, {'entity': 'variable size', 'concept_id': 'C1866144', 'confidence': 0.8559831976890564}, {'entity': 'fetal', 'concept_id': 'C0015965', 'confidence': 1.0}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'placenta', 'concept_id': 'C0032043', 'confidence': 1.0}], [{'entity': 'chorionic villi', 'concept_id': 'C0008508', 'confidence': 1.0}, {'entity': 'maternal site', 'concept_id': 'C0026591', 'confidence': 0.7640593647956848}], [{'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}, {'entity': 'chorion', 'concept_id': 'C0008503', 'confidence': 0.9999998807907104}, {'entity': 'blood', 'concept_id': 'C0005767', 'confidence': 1.0}], [{'entity': 'Intercommunicating', 'concept_id': 'C0205196', 'confidence': 0.8271207213401794}, {'entity': 'vascular spaces', 'concept_id': 'C0225983', 'confidence': 0.819495439529419}, {'entity': 'mass', 'concept_id': 'C0577559', 'confidence': 1.0}], [{'entity': 'Focal area', 'concept_id': 'C0205234', 'confidence': 0.7634891271591187}, {'entity': 'calcification', 'concept_id': 'C0006660', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_396",
"caption_rating": "7"
},
{
"": "1007587",
"caption": "Multinucleated giant cells are foreign body giant cells seen around foreign material that cannot be easily phagocytosed or destroyed.",
"image_path": "rHSTVT91c8Q_image_043c7623-105d-45ac-98f1-f39475e0b124.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Cardiac', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Foreign body giant cells seen around some foreign material', 'Brown pigment which is very probably hemosiderin', 'Brown pigment which is very probably hemosiderin']",
"noisy_text": " multinucleated giant cells are actually transformed macrophages and they are also called foreign body cells or those are those are cells seen around some foreign material that cannot be easily phagocytosed or destroyed and they are transformed macrophages. Here we can see some brown pigment which is very probably hemosiderin and if we want to be sure we can use prussian blue stain or pearls pearls stain and the hemosiderin would turn into blue pigment because of iron ions that mediates this blue reaction. Macrophages that phagocytose the hemosiderin are sometimes called siderophages. Here",
"corrected_text": " multinucleated giant cells are actually transformed macrophages and they are also called foreign body cells or those are those are cells seen around some foreign material that cannot be easily phagocytosed or destroyed and they are transformed macrophages. Here we can see some brown pigment which is very probably hemosiderin and if we want to be sure we can use prussian blue stain or pearls pearls stain and the hemosiderin would turn into blue pigment because of iron ions that mediates this blue reaction. Macrophages that phagocytose the hemosiderin are sometimes called siderophages. Here",
"med_umls_ids": "[[{'entity': 'Multinucleated giant cells', 'concept_id': 'C0017526', 'confidence': 0.9999999403953552}, {'entity': 'foreign body giant cells', 'concept_id': 'C0017527', 'confidence': 1.0}, {'entity': 'foreign material', 'concept_id': 'C0016542', 'confidence': 1.0}, {'entity': 'phagocytosed', 'concept_id': 'C0031308', 'confidence': 0.920818030834198}, {'entity': 'destroyed', 'concept_id': 'C3830528', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_397",
"caption_rating": "9"
},
{
"": "1008648",
"caption": "Too many melanocytes in the matrix are highly suspicious for melanoma in situ.",
"image_path": "8S4LeiO6Bbk_image_59b75d51-8011-42e1-9838-b22e2144b31f.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Presence of several melanocytes', 'too many melanocytes', 'Presence of several melanocytes', 'forming nests', 'confluence solitary units', 'matrix epithelium', 'basal layer of the matrix', 'upper portions of the matrix', 'pagetoid pattern', 'too many melanocytes', 'basal layer of the matrix', 'upper portions of the matrix']",
"noisy_text": " examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matricle epithelium in the matricle layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that being said, we'll go ahead and move on to slide number two, which was a melanin A or Mk1 immunohistochemical stain of this same piece of tissue. Underneath this bubble here we have our control. This is",
"corrected_text": " examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matrix epithelium in the matrix layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that being said, we'll go ahead and move on to slide number two, which was a melanin A or Mk1 immunohistochemical stain of this same piece of tissue. Underneath this bubble here we have our control. This is",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'nests', 'concept_id': 'C0035253', 'confidence': 0.7275967001914978}, {'entity': 'confluence', 'concept_id': 'C0226863', 'confidence': 0.857487678527832}, {'entity': 'solitary units', 'concept_id': 'C0205171', 'confidence': 0.7227572798728943}, {'entity': 'base', 'concept_id': 'C0002055', 'confidence': 1.0}, {'entity': 'matrix epithelium', 'concept_id': 'C0014609', 'confidence': 0.7584323883056641}, {'entity': 'matrix layer', 'concept_id': 'C0331858', 'confidence': 0.71736741065979}, {'entity': 'basal layer', 'concept_id': 'C0221925', 'confidence': 1.0}, {'entity': 'matrix', 'concept_id': 'C0331858', 'confidence': 1.0}, {'entity': 'upper portions', 'concept_id': 'C0449719', 'confidence': 0.6251541972160339}, {'entity': 'matrix', 'concept_id': 'C0331858', 'confidence': 1.0}, {'entity': 'pagetoid', 'concept_id': 'C1518847', 'confidence': 0.8801172375679016}, {'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}], [{'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'matrix', 'concept_id': 'C0331858', 'confidence': 1.0}, {'entity': 'suspicious', 'concept_id': 'C0750493', 'confidence': 1.0}, {'entity': 'melanoma', 'concept_id': 'C0025202', 'confidence': 1.0}, {'entity': 'in situ', 'concept_id': 'C0444498', 'confidence': 0.9999999403953552}]]",
"magnification": "1.0",
"height": "758.0",
"width": "1920.0",
"id": "test_398",
"caption_rating": "8"
},
{
"": "1004931",
"caption": "Fibrosis and sparse infiltrative lymphocytes, and in this case, a few plasma cells.",
"image_path": "hoV-JkD6Wb0_image_2e6ed1f2-9837-44ad-b695-2071a6947a39.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['large fat microcysts', 'membranous lipodystrophy', 'fibrosis', 'lipophages', 'plasma cells', 'lipophages']",
"noisy_text": " ruptured and fused, and so we've got these large fat microcysts, and if we look at the periphery of the fat microcyst, we've got this lipomembranous change, this kind of arabesque-type fibular material out at the periphery, which basically represents coalescence of remnant cell walls of adipocytes. In addition, within the surrounding tissue, there's a little bit of fibrosis. There are a few lipophages and a very sparse infiltrative lymphocytes, and in this case, a few plasma cells, and of course, these findings are virtually pathognomonic for lipodermatosclerosis, especially in this clinical setting. Personally, in my practice, I see a lot more biopsies",
"corrected_text": " ruptured and fused, and so we've got these large fat microcysts, and if we look at the periphery of the fat microcyst, we've got this lipomembranous change, this kind of arabesque-type fibular material out at the periphery, which basically represents coalescence of remnant cell walls of adipocytes. In addition, within the surrounding tissue, there's a little bit of fibrosis. There are a few lipophages and a very sparse infiltrative lymphocytes, and in this case, a few plasma cells, and of course, these findings are pathognomonic for lipodermatosclerosis, especially in this clinical setting. Personally, in my practice, I see a lot more biopsies",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'fat microcysts', 'concept_id': 'C1513269', 'confidence': 0.871767520904541}, {'entity': 'membranous lipodystrophy', 'concept_id': 'C0406599', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'coalescence', 'concept_id': 'C4727092', 'confidence': 0.8749340176582336}, {'entity': 'remnant', 'concept_id': 'C3272697', 'confidence': 1.0}, {'entity': 'cell walls', 'concept_id': 'C0007623', 'confidence': 1.0}, {'entity': 'adipocytes', 'concept_id': 'C0206131', 'confidence': 1.0}], [{'entity': 'Fibrosis', 'concept_id': 'C0016059', 'confidence': 1.0}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}], [{'entity': 'Pathognomonic findings', 'concept_id': 'C2986472', 'confidence': 0.7794376611709595}, {'entity': 'lipodermatosclerosis', 'concept_id': 'C0406500', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_399",
"caption_rating": "8"
},
{
"": "1007049",
"caption": "Description of a benign-looking tumor with delicate stringy fine collagen and bland fibroblastic looking cells. The importance of recognizing the histologic pattern to correctly diagnose tumors.",
"image_path": "QDb68_G1HR4_image_1a8c9f50-8a25-4a40-b18a-8db78ba0d8c3.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['fibroblastic looking cells']",
"noisy_text": " Let me flip the condenser back so we can see it more clearly. So this is what it looks like without the condenser on, again, very delicate stringy fine collagen and in between these bland, bland, thin, not atypical at all, fibroblastic looking cells. And I could show anyone a picture of that, one picture. That does not look malignant, it looks totally benign by all of the rules that we usually use to assess malignancy histologically and cytologically. This is the most important take home point from this whole video. These tumors do not usually look malignant and because of that if you don't recognize the pattern, it is so easy to misdiagnose them as a benign thing. So I think a couple ways to avoid that is A, don't look at this and say, oh look it's a benign and it looks fibroblastic, let's call it a fibroma, don't do that. The other thing, one of my mentors, one of my greatest mentors, the one who made me decide to pursue academic medicine and teaching, Dr. Jay Rowe from Houston Methodist Hospital, what he told me, it was I think some great advice, he said if you see a lesion that you think is a neoplasm and you think it's a benign neoplasm but you don't know a name for it, don't just sign it out and diagnose it as benign neoplasm, not otherwise specified unless you're an expert in that particular subspecialty. Go and show it to an expert if you have a case like that and the reason is that maybe most of the time you'll be okay doing that but you're going to end up having things like this that are known entities that don't look malignant. In soft tissue we have quite a few of these, we have low grade fibromyxoid sarcoma, myxoid liposarcoma also looks totally benign most of the time unless you recognize the pattern. So this is another one of those tumors where the histologic pattern is really the key to recognizing the diagnosis. So I'm going to go in even higher power to convince you, yes these are sarcoma cells right here.",
"corrected_text": " Let me flip the condenser back so we can see it more clearly. So this is what it looks like without the condenser on, again, very delicate stringy fine collagen and in between these bland, bland, thin, not atypical at all, fibroblastic looking cells. And I could show anyone a picture of that, one picture. That does not look malignant, it looks totally benign by all of the rules that we usually use to assess malignancy histologically and cytology. This is the most important take home point from this whole video. These tumors do not usually look malignant and because of that if you don't recognize the pattern, it is so easy to misdiagnose them as a benign thing. So I think a couple ways to avoid that is A, don't look at this and say, oh look it's a benign and it looks fibroblastic, let's call it a fibroma, don't do that. The other thing, one of my mentors, one of my greatest mentors, the one who made me decide to pursue academic medicine and teaching, Dr. Jay Rowe from Houston Methodist Hospital, what he told me, it was I think some great advice, he said if you see a lesion that you think is a neoplasm and you think it's a benign neoplasm but you don't know a name for it, don't just sign it out and diagnose it as benign neoplasm, not otherwise specified unless you're an expert in that particular subspecialty. Go and show it to an expert if you have a case like that and the reason is that maybe most of the time you'll be okay doing that but you're going to end up having things like this that are known entities that don't look malignant. In soft tissue we have quite a few of these, we have low grade fibromyxoid sarcoma, myxoid liposarcoma also looks totally benign most of the time unless you recognize the pattern. So this is another one of those tumors where the histologic pattern is really the key to recognizing the diagnosis. So I'm going to go in even higher power to convince you, yes these are sarcoma cells right here.",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'benign-looking tumor', 'concept_id': 'C0086692', 'confidence': 0.5747699737548828}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'bland', 'concept_id': 'C0227475', 'confidence': 0.7435316443443298}, {'entity': 'fibroblastic', 'concept_id': 'C0016030', 'confidence': 0.8876925110816956}, {'entity': 'histologic', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_400",
"caption_rating": "8"
},
{
"": "1006118",
"caption": "Spindle cell non-epithelial neoplasms include muscle and neural tumors.",
"image_path": "LlPaENuqzVQ_image_8aba35ce-9548-4687-84be-cb4024c91599.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['smooth muscle', 'skeletal muscle', 'spindle cell non-epithelial neoplasms', 'atypical fibroxanthoma', 'neural tumors']",
"noisy_text": " So basically, just to kind of go backwards, more generic, muscle. Yeah. Do it. OK. And then there's two types of muscle, right? There's smooth muscle, or three, cardiac muscle, hopefully, to see that in the skin. But smooth and skeletal muscle, which we hardly ever see skeletal muscle neoplasms in dermatology. So it's almost always smooth muscle when we're looking at muscle. And there's probably really only two or three spindle cell non-epithelial neoplasms you need to know about. So muscle's one. What are the other two, basically? Like AFX? Yeah, but more generic. So what's the differentiation in an atypical fibrous anthoma? Just think of the cells that have become malignant in that. They're obviously not muscle cells. Neural? Neural's the other one. Those are the three major ones. But the one that you're missing is the center one there. What else lives in your dermis normally here? So we're going to go back. Fibroblast. Yeah,",
"corrected_text": " So basically, just to kind of go backwards, more generic, muscle. Yeah. Do it. OK. And then there's two types of muscle, right? There's smooth muscle, or three, cardiac muscle, hopefully, to see that in the skin. But smooth and skeletal muscle, which we hardly ever see skeletal muscle neoplasms in dermatology. So it's almost always smooth muscle when we're looking at muscle. And there's probably really only two or three spindle cell non-epithelial neoplasms you need to know about. So muscle's one. What are the other two, basically? Like AFX? Yeah, but more generic. So what's the differentiation in an atypical fibroxanthoma? Just think of the cells that have become malignant in that. They're obviously not muscle cells. Neural? Neural's the other one. Those are the three major ones. But the one that you're missing is the center one there. What else lives in your dermis normally here? So we're going to go back. Fibroblast. Yeah,",
"med_umls_ids": "[[{'entity': 'Smooth', 'concept_id': 'C0205357', 'confidence': 1.0}, {'entity': 'skeletal muscle', 'concept_id': 'C0242692', 'confidence': 1.0}, {'entity': 'muscle', 'concept_id': 'C0026845', 'confidence': 1.0}, {'entity': 'smooth muscle', 'concept_id': 'C1267092', 'confidence': 1.0}, {'entity': 'dermatology', 'concept_id': 'C0011627', 'confidence': 1.0}], [{'entity': 'Spindle cell', 'concept_id': 'C0682540', 'confidence': 0.9999999403953552}, {'entity': 'non-epithelial neoplasms', 'concept_id': 'C1368683', 'confidence': 0.8066584467887878}, {'entity': 'muscle', 'concept_id': 'C0026845', 'confidence': 1.0}, {'entity': 'neural tumors', 'concept_id': 'C1334956', 'confidence': 0.849646270275116}], [{'entity': 'Atypical fibroxanthoma', 'concept_id': 'C0346053', 'confidence': 1.0}, {'entity': 'malignant tumor', 'concept_id': 'C0006826', 'confidence': 1.0}, {'entity': 'muscle cells', 'concept_id': 'C0596981', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_401",
"caption_rating": "8"
},
{
"": "1004644",
"caption": "Chronic atrophic gastritis with intestinal metaplasia and muscularization of the lamina propria is the diagnosis.",
"image_path": "r7OA0Trj5hQ_image_6383bc61-ea49-4ba7-b64c-3752ed875092.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['muscle fibers', 'intestinal metaplasia', 'lamina propria', 'muscle fibers', 'intestinal metaplasia', 'lamina propria']",
"noisy_text": " where, again, you can see the muscle fibers running into the lamina propria. If you are in doubt, you can use the trichrome strain, where you can identify the muscle running up there. And you can see nice intestinal metaplasia there. Again, the number of glands are less in here. So this is chronic atrophic gastritis with intestinal metaplasia with muscularization of the lamina propria. More than one pathology involved in this biopsy. Plastic changes seen above are known as TIS. Once they cross the muscular ischemicosa, then only they are eligible for T1. So muscular ischemicosa acts like",
"corrected_text": " where, again, you can see the muscle fibers running into the lamina propria. If you are in doubt, you can use the trichrome strain, where you can identify the muscle running up there. And you can see nice intestinal metaplasia there. Again, the number of glands are less in here. So this is chronic atrophic gastritis with intestinal metaplasia with muscularization of the lamina propria. More than one pathology involved in this biopsy. Plastic changes seen above are known as TIS. Once they cross the muscularis propria, then only they are eligible for T1. So muscularis propria acts like",
"med_umls_ids": "[[{'entity': 'Muscle fibers', 'concept_id': 'C0242697', 'confidence': 1.0}, {'entity': 'running', 'concept_id': 'C0035953', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}], [{'entity': 'Intestinal metaplasia', 'concept_id': 'C0334037', 'confidence': 1.0}], [{'entity': 'Chronic atrophic gastritis', 'concept_id': 'C0017154', 'confidence': 1.0}, {'entity': 'intestinal metaplasia', 'concept_id': 'C0334037', 'confidence': 1.0}, {'entity': 'muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'Plastic changes', 'concept_id': 'C0392747', 'confidence': 0.7598782777786255}, {'entity': 'TIS', 'concept_id': 'C0475413', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_402",
"caption_rating": "9"
},
{
"": "1005827",
"caption": "Large histiocytes containing lipid, some of which are multinucleated and ringed siderophages.",
"image_path": "8S4LeiO6Bbk_image_c5f14cb3-8d7b-4a19-89cc-edafae5bc6ad.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['lipid vacuoles', 'multinucleated histiocytes', 'ringed siderophages', 'pigmented histiocytes', 'hemocyanin']",
"noisy_text": " large histiocytes containing lipid. Some of them are multi-nucleated and some of these are actually ringed siderophages. So we see large multi-nucleated histiocytes with a ring of nuclei and they contain not only lipid vacuoles but hemocentaurant. And these are particularly common in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes as suspected is hemocentaurant. If you notice, it's got kind of that golden brown color. If you had a sub-stage condenser or a fine focus knob, you would see that it's somewhat refractile, but unfortunately, we can't use that particular tool when we're looking at scanned images.",
"corrected_text": " large histiocytes containing lipid. Some of them are multinucleated and some of these are actually ringed siderophages. So we see large multinucleated histiocytes with a ring of nuclei and they contain not only lipid vacuoles but hemosiderin. And these are particularly common in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes as suspected is hemosiderin. If you notice, it's got kind of that golden brown color. If you had a sub-stage condenser or a fine focus knob, you would see that it's somewhat refractile, but unfortunately, we can't use that particular tool when we're looking at scanned images.",
"med_umls_ids": "[[{'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'lipid', 'concept_id': 'C0023779', 'confidence': 1.0}, {'entity': 'multinucleated', 'concept_id': 'C0333740', 'confidence': 1.0}, {'entity': 'ringed', 'concept_id': 'C0325501', 'confidence': 0.77345871925354}, {'entity': 'siderophages', 'concept_id': 'C1136253', 'confidence': 0.7251443266868591}], [{'entity': 'Hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}], [{'entity': 'Pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_403",
"caption_rating": "8"
},
{
"": "1005209",
"caption": "Infected histiocytes are present.",
"image_path": "hoV-JkD6Wb0_image_653124da-8816-48ca-93a4-468df20be9f0.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['cytoplasm', 'organisms', 'infected histiocytes', 'large histiocytes']",
"noisy_text": " we can see that we actually have very large histiocytes. We've cleared out cytoplasm and with a little effort, one could see that there were organisms present within the cytoplasm of these histiocytes producing so-called parasitized histiocytes. And the organisms are very small, one to two microns. And we can use our erythrocyte here as kind of a ruler. Most erythrocytes and lymphocytes have nuclei that have diameters about five to six microns. And so you can see that these round organisms at the periphery of the histiocytes are about one to two microns. And as you'll see in a subsequent slide, when you see parasitized histiocytes with organisms of this size in",
"corrected_text": " we can see that we actually have very large histiocytes. We've cleared out cytoplasm and with a little effort, one could see that there were organisms present within the cytoplasm of these histiocytes producing so-called parasitized histiocytes. And the organisms are very small, one to two microns. And we can use our erythrocyte here as kind of a ruler. Most erythrocytes and lymphocytes have nuclei that have diameters about five to six microns. And so you can see that these round organisms at the periphery of the histiocytes are about one to two microns. And as you'll see in a subsequent slide, when you see parasitized histiocytes with organisms of this size in",
"med_umls_ids": "[[{'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'organisms', 'concept_id': 'C0029235', 'confidence': 0.9999998807907104}, {'entity': 'cytoplasm', 'concept_id': 'C0010834', 'confidence': 1.0}], [{'entity': 'Infected', 'concept_id': 'C0439663', 'confidence': 1.0}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}], [{'entity': 'organisms', 'concept_id': 'C0029235', 'confidence': 0.9999998807907104}, {'entity': 'microns', 'concept_id': 'C0439201', 'confidence': 0.9999999403953552}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}], [{'entity': 'infected', 'concept_id': 'C0439663', 'confidence': 1.0}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'round organisms', 'concept_id': 'C0029235', 'confidence': 0.813967227935791}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'microns', 'concept_id': 'C0439201', 'confidence': 0.9999999403953552}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_404",
"caption_rating": "7"
},
{
"": "1009174",
"caption": "The hamartoma is located at the level of the mantle zone of the hair follicle.",
"image_path": "LlPaENuqzVQ_image_2668b8db-1ce3-4137-8b32-82b077d5206e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['hamartoma', 'hamartoma']",
"noisy_text": " it almost looks like a mini hair follicle that didn't really form. And then when you look at a hair follicle, it's comprised not only of the epithelial component, but there's also a periepithelial sheath around it, a fibrous sheath around the hair follicle. And so this is a hammertoma that involves both of those. So it's got a fibrous element to it. And then it's got this little primitive follicular element to it. And this is all kind of a little, you know, hammertoma going on at the level of the mantle zone of the hair follicle. So do you have any idea what this neoplasm is, this little benign hammertoma is here? Honestly, like to name it? No, I",
"corrected_text": " it almost looks like a mini hair follicle that didn't really form. And then when you look at a hair follicle, it's comprised not only of the epithelial component, but there's also a periepithelial sheath around it, a fibrous sheath around the hair follicle. And so this is a hamartoma that involves both of those. So it's got a fibrous element to it. And then it's got this little primitive follicular element to it. And this is all kind of a little, you know, hamartoma going on at the level of the mantle zone of the hair follicle. So do you have any idea what this neoplasm is, this little benign hamartoma is here? Honestly, like to name it? No, I",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'hamartoma', 'concept_id': 'C0018552', 'confidence': 0.9999999403953552}, {'entity': 'epithelial', 'concept_id': 'C0221908', 'confidence': 1.0}, {'entity': 'fibrous sheath', 'concept_id': 'C1185724', 'confidence': 1.0}, {'entity': 'hair follicle', 'concept_id': 'C0221971', 'confidence': 1.0}], [{'entity': 'hamartoma', 'concept_id': 'C0018552', 'confidence': 0.9999999403953552}, {'entity': 'level', 'concept_id': 'C0441889', 'confidence': 1.0}, {'entity': 'mantle', 'concept_id': 'C0232445', 'confidence': 0.8497024178504944}, {'entity': 'zone', 'concept_id': 'C1710706', 'confidence': 1.0}, {'entity': 'hair follicle', 'concept_id': 'C0221971', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_405",
"caption_rating": "9"
},
{
"": "1009247",
"caption": "Single layer of cells with mucin present, stratification and loss of mucin seen in another area.",
"image_path": "r7OA0Trj5hQ_image_716d9277-9b40-4609-9393-0ad09ceba939.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Stratification and loss of mucin seen in one area.', 'Stratification and loss of mucin seen in one area.']",
"noisy_text": " Here, single layer of cells, mucin is present, whereas here, stratification has started, loss of mucin. So stratification, loss of mucin. And when you go to high power, you can see lot of apoptosis and lot of mitosis. So this is a diagnostic criteria for dysplasia. Stratification, loss of mucin. See the amount of goblet cells, mucin. You see the amount of goblet cells. This loss of mucin or less of mucin. Again, another normal epithelium. So this is the area, pyramidal area, that is pathologic in this biopsy. And there",
"corrected_text": " Here, single layer of cells, mucin is present, whereas here, stratification has started, loss of mucin. So stratification, loss of mucin. And when you go to high power, you can see lot of apoptosis and lot of mitosis. So this is a diagnostic criteria for dysplasia. Stratification, loss of mucin. See the amount of goblet cells, mucin. You see the amount of goblet cells. This loss of mucin or less of mucin. Again, another normal epithelium. So this is the area, pyramidal area, that is pathologic in this biopsy. And there",
"med_umls_ids": "[[{'entity': 'Single layer of', 'concept_id': 'C0934502', 'confidence': 0.6987537741661072}, {'entity': 'mucin', 'concept_id': 'C0026682', 'confidence': 1.0}, {'entity': 'stratification', 'concept_id': 'C1514983', 'confidence': 1.0}, {'entity': 'loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'mucin', 'concept_id': 'C0026682', 'confidence': 1.0}, {'entity': 'area', 'concept_id': 'C0017446', 'confidence': 1.0}], [{'entity': 'apoptosis', 'concept_id': 'C0162638', 'confidence': 1.0}, {'entity': 'mitosis', 'concept_id': 'C0026255', 'confidence': 0.9999998807907104}, {'entity': 'diagnostic criteria', 'concept_id': 'C0679228', 'confidence': 1.0}, {'entity': 'dysplasia', 'concept_id': 'C0334044', 'confidence': 1.0}], [{'entity': 'Amount', 'concept_id': 'C1265611', 'confidence': 0.9999998807907104}, {'entity': 'goblet cells', 'concept_id': 'C0506994', 'confidence': 0.9999999403953552}, {'entity': 'mucin', 'concept_id': 'C0026682', 'confidence': 1.0}, {'entity': 'normal epithelium', 'concept_id': 'C0014609', 'confidence': 0.8199569582939148}], [{'entity': 'Pyramidal area', 'concept_id': 'C2323328', 'confidence': 0.8333803415298462}, {'entity': 'pathologic', 'concept_id': 'C1521733', 'confidence': 1.0}, {'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_406",
"caption_rating": "8"
},
{
"": "1006848",
"caption": "The specimen has a very thick stratum corneum and a marked absence of hair follicles.",
"image_path": "8S4LeiO6Bbk_image_76bedbf1-de38-4994-8b90-f18fe5735913.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['dome-shaped papule', 'acral site', 'thick stratum corneum', 'absence of hair follicles', 'fibrovascular core', 'nerve fascicles', 'spindle-shaped cells', 'S100', 'SOX10', 'rudimentary supernumerary digit']",
"noisy_text": " we've got a dome-shaped papule and that the biopsy is from an acral site. Notice that we've got a very very thick stratum corneum and a marked to virtual absence of hair follicles within the specimen. We do have kind of this fibrovascular core and of course in the center of the fibrovascular core here we've got several well-defined nerve fascicles and the spindled cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions",
"corrected_text": " we've got a dome-shaped papule and that the biopsy is from an acral site. Notice that we've got a very very thick stratum corneum and a marked to virtual absence of hair follicles within the specimen. We do have kind of this fibrovascular core and of course in the center of the fibrovascular core here we've got several well-defined nerve fascicles and the spindle cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions",
"med_umls_ids": "[[{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'acral site', 'concept_id': 'C0439746', 'confidence': 0.717435359954834}, {'entity': 'dome-shaped papule', 'concept_id': 'C1711316', 'confidence': 0.752353847026825}], [{'entity': 'specimen', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'stratum corneum', 'concept_id': 'C0221921', 'confidence': 1.0}, {'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'hair follicles', 'concept_id': 'C0221971', 'confidence': 0.9999998807907104}], [{'entity': 'fibrovascular', 'concept_id': 'C0392759', 'confidence': 1.0}, {'entity': 'nerve fascicles', 'concept_id': 'C1185741', 'confidence': 0.8332967758178711}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'S100', 'concept_id': 'C3273837', 'confidence': 1.0}, {'entity': 'SOX10', 'concept_id': 'C1420317', 'confidence': 0.9999998807907104}, {'entity': 'neural tumor', 'concept_id': 'C1334956', 'confidence': 1.0}], [{'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'rudimentary supernumerary digit', 'concept_id': 'C0152427', 'confidence': 0.8142021894454956}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_407",
"caption_rating": "9"
},
{
"": "1006368",
"caption": "Well-defined nerve fascicles with spindle-shaped cells, which are positive with S100 and SOX10, defining the diagnosis of rudimentary supernumerary digit.",
"image_path": "8S4LeiO6Bbk_image_0b555a52-b342-471e-b863-fcfab968abaa.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['nerve fascicles', 'spindle-shaped cells', 'rudimentary supernumerary digit', 'ulnar aspect of the fifth digit', 'acquired digital fibroma', 'acquired digital fibrokeratoma', 'trichilemmal cyst']",
"noisy_text": " core here we've got several well-defined nerve fascicles and the spindled cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions of course tend to occur along the ulnar eye aspect of the fifth digit. They're not infrequently bilateral and the key differential here of course is an acquired digital fibroma or an acquired digital fibrocarotoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if",
"corrected_text": " core here we've got several well-defined nerve fascicles and the spindle cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions of course tend to occur along the ulnar eye aspect of the fifth digit. They're not infrequently bilateral and the key differential here of course is an acquired digital fibroma or an acquired digital fibrokeratoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if",
"med_umls_ids": "[[{'entity': 'Well-defined nerve fascicles', 'concept_id': 'C1185741', 'confidence': 0.5682494640350342}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'S100', 'concept_id': 'C3273837', 'confidence': 1.0}, {'entity': 'SOX10', 'concept_id': 'C1420317', 'confidence': 0.9999998807907104}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'rudimentary supernumerary digit', 'concept_id': 'C0152427', 'confidence': 0.8142021894454956}], [{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'ulnar', 'concept_id': 'C0442044', 'confidence': 1.0}, {'entity': 'aspect', 'concept_id': 'C1547011', 'confidence': 1.0}, {'entity': 'fifth digit', 'concept_id': 'C0230403', 'confidence': 0.912693440914154}, {'entity': 'bilateral', 'concept_id': 'C0238767', 'confidence': 1.0}], [{'entity': 'differential diagnosis', 'concept_id': 'C0011906', 'confidence': 1.0}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}, {'entity': 'digital fibroma', 'concept_id': 'C4538745', 'confidence': 0.8997364640235901}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}], [{'entity': 'Trichilemmal cyst', 'concept_id': 'C2266788', 'confidence': 1.0}, {'entity': 'biopsy specimen', 'concept_id': 'C0677862', 'confidence': 1.0}, {'entity': 'slide number', 'concept_id': 'C3828004', 'confidence': 0.8261933326721191}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_408",
"caption_rating": "9"
},
{
"": "1006397",
"caption": "Cribriform pattern and loose, edematous, and vascular stroma.",
"image_path": "8S4LeiO6Bbk_image_1140d29b-7b6c-44f2-84a9-7cac8ab86b82.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['epithelial tumor', 'cytoplasm', 'vesicular chromatin pattern', 'lymphocytes', 'duct formation', 'epithelial tumor', 'cytoplasm', 'vesicular chromatin pattern', 'lymphocytes', 'duct formation']",
"noisy_text": " If we move to higher power, we can see that we're dealing with an epithelial rather than a mosaicable tumor. We've got interconnected cords and strands. We have somewhat of a ribiform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of the cells are round to oval. They're fairly large. These cells have some faint eosinophilic to pale gray cytoplasm, although this cytoplasm is kind of difficult to see. Some of these cells have an evenly dispersed or vesicular chromatin pattern, and other nuclei are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and",
"corrected_text": " If we move to higher power, we can see that we're dealing with an epithelial rather than a mesenchymal tumor. We've got interconnected cords and strands. We have somewhat of a cribriform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of the cells are round to oval. They're fairly large. These cells have some faint eosinophilic to pale gray cytoplasm, although this cytoplasm is kind of difficult to see. Some of these cells have an evenly dispersed or vesicular chromatin pattern, and other nuclei are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'epithelial tumor', 'concept_id': 'C1368683', 'confidence': 0.9999999403953552}, {'entity': 'cords', 'concept_id': 'C0034869', 'confidence': 0.801885187625885}, {'entity': 'strands', 'concept_id': 'C0600383', 'confidence': 0.800572395324707}], [{'entity': 'Cribriform pattern', 'concept_id': 'C1333163', 'confidence': 1.0}, {'entity': 'loose', 'concept_id': 'C0205407', 'confidence': 1.0}, {'entity': 'edematous', 'concept_id': 'C0013604', 'confidence': 1.0}, {'entity': 'vascular stroma', 'concept_id': 'C0005847', 'confidence': 0.8046398758888245}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'cell types', 'concept_id': 'C0007634', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'eosinophilic', 'concept_id': 'C0333930', 'confidence': 1.0}, {'entity': 'pale', 'concept_id': 'C0030232', 'confidence': 1.0}, {'entity': 'gray cytoplasm', 'concept_id': 'C0010834', 'confidence': 0.8177905678749084}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'duct', 'concept_id': 'C0687028', 'confidence': 1.0}, {'entity': 'formation', 'concept_id': 'C0220781', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_409",
"caption_rating": "8"
},
{
"": "1005324",
"caption": "Translocation-associated sarcomas have the same molecular abnormality in every single cell, making them look monotonous and uniform rather than pleomorphic.",
"image_path": "QDb68_G1HR4_image_7bbe5025-c6e6-4283-8f18-418d3f16e50e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Cytologic feature of low-grade fibromyxoid sarcoma', 'Fibrous area with delicate collagen in the background', 'Bland spindle cells']",
"noisy_text": " videos this is a true statement about many of the translocation associated sarcomas. They have the same molecular abnormality in every single cell so all the cells look alike. They look monotonous and uniform rather than pleomorphic, okay? So there's a few exceptions to this we'll talk about in a minute but this is the cytologic feature of low grade fibromyxoid sarcoma so that's the fibrous area, delicate collagen kind of in the background, little tiny bit of myxoid stuff, bland spindle cells. Let's move",
"corrected_text": " videos this is a true statement about many of the translocation associated sarcomas. They have the same molecular abnormality in every single cell so all the cells look alike. They look monotonous and uniform rather than pleomorphic, okay? So there's a few exceptions to this we'talk about in a minute but this is the cytologic feature of low grade fibromyxoid sarcoma so that's the fibrous area, delicate collagen kind of in the background, little tiny bit of myxoid stuff, bland spindle cells. Let's move",
"med_umls_ids": "[[{'entity': 'Translocation-associated sarcomas', 'concept_id': 'C0084548', 'confidence': 0.724479079246521}, {'entity': 'molecular abnormality', 'concept_id': 'C0262496', 'confidence': 1.0}, {'entity': 'single cell', 'concept_id': 'C0037179', 'confidence': 0.8127751350402832}, {'entity': 'monotonous', 'concept_id': 'C1462306', 'confidence': 0.8221240043640137}, {'entity': 'uniform', 'concept_id': 'C0205375', 'confidence': 1.0}, {'entity': 'pleomorphic', 'concept_id': 'C1514164', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_410",
"caption_rating": "8"
},
{
"": "1008434",
"caption": "Radiation treatment can wipe out tumors, leaving only sclerotic collagen, vascular branching, and mature adipocytes with occasional lipoblasts and myxoid change.",
"image_path": "pBR26SS0FX8_image_decfa00c-795e-44d0-9da3-0464679a982a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Hematopathology', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " and not other parts of pathology where you have to calculate percent of key 67 staining and stuff. So anyway, I don't know if that's a good answer, but it's an honest one. Yeah, so the question brought up is that post treatment, once these tumors have been radiated, they usually, the vast majority of them just completely get wiped out. And all that's left is sclerotic collagen, a little bit of the vascular branchy stuff and mature adipocytes with occasional little tiny lipoblasts, maybe a few pockets of myxoid change. And if there was a round cell component, you'll never know because it usually gets wiped out and blasted by the radiation. So I agree, that's the problem. The trade-off is that doing the needle ahead of time to get the diagnosis on a needle biopsy allows you to make a diagnosis and pre-treat the tumor. The trade-off though, is that on the excision specimen, you'll really never probably know what the original morphology was like. And I feel like this is one of the trade-offs we've made in modern medicine, where there are benefits of having a needle biopsy before excision, a lot of benefits and probably more benefits than risks, but there are some downsides. And that's one of them is pre-treatment, wipes out the original morphology. But again, it's the main difference is the prognosis. The long-term prognosis is worse, unfortunately, for patients that have high-grade round cell morphology. And even though the low-grade myxoid liposarcoma, in the past, there was a thought that like, 90% of the patients were gonna be okay and 10% would get METs. But I think with longer follow-up, we started to see that a significantly larger number actually even of people with low-grade conventional myxoid liposarcoma will get metastases. I think the WHO says, I think their current quote is between 30 and it's more than 30%, I think. And different studies show different things so that even sometimes it's longer and farther out. Oh yeah, I forgot to mention, the other weird thing that you should know about myxoid liposarcoma, like all sarcomas, it will metastasize the lungs oftentimes. But it",
"corrected_text": " and not other parts of pathology where you have to calculate percent of key 67 staining and stuff. So anyway, I don't know if that's a good answer, but it's an honest one. Yeah, so the question brought up is that post treatment, once these tumors have been radiated, they usually, the vast majority of them just completely get wiped out. And all that's left is sclerotic collagen, a little bit of the vascular branching and mature adipocytes with occasional little tiny lipoblasts, maybe a few pockets of myxoid change. And if there was a round cell component, you'll never know because it usually gets wiped out and blasted by the radiation. So I agree, that's the problem. The trade-off is that doing the needle ahead of time to get the diagnosis on a needle biopsy allows you to make a diagnosis and pre-treat the tumor. The trade-off though, is that on the excision specimen, you'll really never probably know what the original morphology was like. And I feel like this is one of the trade-offs we've made in modern medicine, where there are benefits of having a needle biopsy before excision, a lot of benefits and probably more benefits than risks, but there are some downsides. And that's one of them is pre-treatment, wipes out the original morphology. But again, it's the main difference is the prognosis. The long-term prognosis is worse, unfortunately, for patients that have high-grade round cell morphology. And even though the low-grade myxoid liposarcoma, in the past, there was a thought that like, 90% of the patients were gonna be okay and 10% would get METs. But I think with longer follow-up, we started to see that a significantly larger number actually even of people with low-grade conventional myxoid liposarcoma will get metastases. I think the WHO says, I think their current quote is between 30 and it's more than 30%, I think. And different studies show different things so that even sometimes it's longer and farther out. Oh yeah, I forgot to mention, the other weird thing that you should know about myxoid liposarcoma, like all sarcomas, it will metastasize the lungs oftentimes. But it",
"med_umls_ids": "[[{'entity': 'Radiation treatment', 'concept_id': 'C1522449', 'confidence': 0.9999999403953552}, {'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'sclerotic', 'concept_id': 'C0036429', 'confidence': 0.9999999403953552}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'vascular branching', 'concept_id': 'C0005847', 'confidence': 0.7225151658058167}, {'entity': 'mature', 'concept_id': 'C0205286', 'confidence': 1.0}, {'entity': 'adipocytes', 'concept_id': 'C0206131', 'confidence': 1.0}, {'entity': 'lipoblasts', 'concept_id': 'C0225323', 'confidence': 0.8551441431045532}, {'entity': 'myxoid change', 'concept_id': 'C0205295', 'confidence': 0.815497636795044}], [{'entity': 'Needle biopsy', 'concept_id': 'C0005560', 'confidence': 1.0}, {'entity': 'excision', 'concept_id': 'C0015252', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'pre-treatment', 'concept_id': 'C0419819', 'confidence': 0.7933163046836853}, {'entity': 'original', 'concept_id': 'C0205313', 'confidence': 1.0}, {'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}], [{'entity': 'Prognosis', 'concept_id': 'C0033325', 'confidence': 1.0}, {'entity': 'patients', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'high-grade round cell', 'concept_id': 'C1512433', 'confidence': 0.7649602890014648}, {'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}], [{'entity': 'Low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'myxoid liposarcoma', 'concept_id': 'C0206634', 'confidence': 1.0}, {'entity': 'metastasize', 'concept_id': 'C0027627', 'confidence': 1.0}], [{'entity': 'Myxoid liposarcoma', 'concept_id': 'C0206634', 'confidence': 1.0}, {'entity': 'metastasize', 'concept_id': 'C0027627', 'confidence': 1.0}, {'entity': 'lungs', 'concept_id': 'C0024109', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_411",
"caption_rating": "8"
},
{
"": "1007064",
"caption": "The band of inflammatory cells and capillaries is thick and irregular, with feet-like projections into the lamina propria.",
"image_path": "sDFjOtMAYrk_image_2ace38fc-f658-4737-9ada-dd62d9eb8ba1.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['gland dropout', 'lamina propria', 'inflammatory cells', 'plasma cells', 'lymphocytes', 'eosinophils', 'capillaries', 'epithelium', 'gland dropout', 'lamina propria', 'inflammatory cells', 'plasma cells', 'lymphocytes', 'eosinophils', 'capillaries', 'epithelium']",
"noisy_text": " you know, gland dropout here and there, but that's okay. What else? Yeah. So expansion of the lamina appropriate by inflammatory cells that includes plasma cells, lymphocytes, and some eos. And what else? Yeah, exactly. So the band interrupts inflammatory cells and capillaries, and it's not just the thickness of the band that really catches your eyes, the irregularity of it. So you don't have a thin smooth line anymore. It's just, you know, thick and irregular, just just throwing like feet down into the, into the lamina appropriate. There are also a few lymphocytes in the epithelium, but that's not the main finding. The other thing you might find",
"corrected_text": " you know, gland dropout here and there, but that's okay. What else? Yeah. So expansion of the lamina appropriate by inflammatory cells that includes plasma cells, lymphocytes, and some eos. And what else? Yeah, exactly. So the band interrupts inflammatory cells and capillaries, and it's not just the thickness of the band that really catches your eyes, the irregularity of it. So you don't have a thin smooth line anymore. It's just, you know, thick and irregular, just just throwing like feet down into the, into the lamina appropriate. There are also a few lymphocytes in the epithelium, but that's not the main finding. The other thing you might find",
"med_umls_ids": "[[{'entity': 'Inflammatory cells', 'concept_id': 'C0440752', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'expansion', 'concept_id': 'C0007595', 'confidence': 0.8664658665657043}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}], [{'entity': 'band', 'concept_id': 'C0175723', 'confidence': 1.0}, {'entity': 'inflammatory cells', 'concept_id': 'C0440752', 'confidence': 1.0}, {'entity': 'capillaries', 'concept_id': 'C0006901', 'confidence': 0.9999998807907104}, {'entity': 'irregular', 'concept_id': 'C0205271', 'confidence': 1.0}, {'entity': 'projections', 'concept_id': 'C0016538', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}], [{'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_412",
"caption_rating": "9"
},
{
"": "1005698",
"caption": "Identification of normal lung tissue with evidence of collapse or atelectasis in one area.",
"image_path": "jF_pj4-tEC8_image_7e91bddf-6e1b-4072-b47f-7ef2e757e1f5.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Pulmonary', 'Cardiac', 'Gastrointestinal']",
"roi_text": "['Evidence of collapse or atelectasis in one area', 'Changes around a bronchial unit.']",
"noisy_text": " normal lung tissue as I peruse around, and I'm going to show you some of the findings. Now, some of it, like you see in this area right here, there is some evidence of collapse or atelectasis, but I want to kind of peruse around first on low power to give you the picture, just stop, now there are some changes around that bronchial unit there that I'm going to highlight as I go around, continue to go around, but I'm going to go on a higher power view to show you some of the changes that I want to highlight in this image here, but we're",
"corrected_text": " normal lung tissue as I peruse around, and I'm going to show you some of the findings. Now, some of it, like you see in this area right here, there is some evidence of collapse or atelectasis, but I want to kind of peruse around first on low power to give you the picture, just stop, now there are some changes around that bronchial unit there that I'm going to highlight as I go around, continue to go around, but I'm going to go on a higher power view to show you some of the changes that I want to highlight in this image here, but we're",
"med_umls_ids": "[[{'entity': 'Identification', 'concept_id': 'C0020792', 'confidence': 1.0}, {'entity': 'normal', 'concept_id': 'C0205307', 'confidence': 1.0}, {'entity': 'lung tissue', 'concept_id': 'C0819757', 'confidence': 1.0}, {'entity': 'evidence', 'concept_id': 'C3887511', 'confidence': 1.0}, {'entity': 'collapse', 'concept_id': 'C0036974', 'confidence': 1.0}, {'entity': 'atelectasis', 'concept_id': 'C0004144', 'confidence': 1.0}, {'entity': 'area', 'concept_id': 'C0017446', 'confidence': 1.0}], [{'entity': 'Changes', 'concept_id': 'C0392747', 'confidence': 1.0}, {'entity': 'bronchial unit', 'concept_id': 'C0205039', 'confidence': 0.8046900629997253}, {'entity': 'power view', 'concept_id': 'C0449911', 'confidence': 0.7891554832458496}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "608.0",
"id": "test_413",
"caption_rating": "8"
},
{
"": "1007866",
"caption": "Presence of spongiosis in the epidermis and neutrophils in a follicular pustule.",
"image_path": "LlPaENuqzVQ_image_dac8cd1f-76b2-4bff-aff3-a082c55d0e92.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['spongiosis', 'follicular pustule', 'neutrophils', 'granulomatous process', 'spongiosis', 'spongiosis', 'follicular pustule', 'neutrophils', 'granulomatous process']",
"noisy_text": " Yeah, it looks like there's more spongiosis in the epidermis. Like there's... I don't know if this is like a pastoral... What's this thing? A hair follicle, or where you might... Yeah, it's a hair follicle. That's probably also a hair follicle. It's probably just off to the side of it a little bit. And so what have we got here? It looks like a lot of neutrophils. Yeah, you got a follicular pustule. So we've got a pustule, follicular pustule, and we've got a granulomatous process here. Do those kind of fit together? Yeah, that made me think of... And I also thought... I saw some eosinophils too, not here, maybe... Oh, maybe there are some there on the other slide. But, oh,",
"corrected_text": " Yeah, it looks like there's more spongiosis in the epidermis. Like there's... I don't know if this is like a pastoral... What's this thing? A hair follicle, or where you might... Yeah, it's a hair follicle. That's probably also a hair follicle. It's probably just off to the side of it a little bit. And so what have we got here? It looks like a lot of neutrophils. Yeah, you got a follicular pustule. So we've got a pustule, follicular pustule, and we've got a granulomatous process here. Do those kind of fit together? Yeah, that made me think of... And I also thought... I saw some eosinophils too, not here, maybe... Oh, maybe there are some there on the other slide. But, oh,",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'spongiosis', 'concept_id': 'C0702120', 'confidence': 1.0}, {'entity': 'epidermis', 'concept_id': 'C0014520', 'confidence': 1.0}, {'entity': 'neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'follicular pustule', 'concept_id': 'C0016436', 'confidence': 1.0}], [{'entity': 'Granulomatous process', 'concept_id': 'C0439667', 'confidence': 0.8522219657897949}, {'entity': 'observed', 'concept_id': 'C1441672', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_414",
"caption_rating": "9"
},
{
"": "1008302",
"caption": "Basal cell carcinoma with sebaceous differentiation should have clefting and palisading with obvious sebaceous differentiation.",
"image_path": "udoW6VSqsm4_image_d54daff7-58ee-4355-9487-59b5c47f6572.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['sebaceoma', 'basal cell carcinoma', 'sebaceous differentiation']",
"noisy_text": " I think we've called it sebaceous epithelium, but again I'm not a big fan of that term. And these look usually like this. They're usually small, round, skin-colored leaves. They kind of look like sebaceous epithelium. They usually come in as real-life basins, so nobody diagnoses these clinically correctly. So these are items in the differential diagnosis. Basal cell with sebaceous differentiation, if you're going to make that diagnosis, it generally needs to look like a basal cell with nice clefting and put the palisade in there and all that, and then have foci where there's obvious sebaceous differentiation. You'll see that on occasion. But I would probably call this sebaceoma, without thinking it's sort of synonymous with sebaceous epithelium. Now, is there any condition you have to worry about with these? With any",
"corrected_text": " I think we've called it sebaceous epithelium, but again I'm not a big fan of that term. And these look usually like this. They're usually small, round, skin-colored leaves. They kind of look like sebaceous epithelium. They usually come in as real-life basins, so nobody diagnoses these clinically correctly. So these are items in the differential diagnosis. Basal cell with sebaceous differentiation, if you're going to make that diagnosis, it generally needs to look like a basal cell with nice clefting and put the palisade in there and all that, and then have foci where there's obvious sebaceous differentiation. You'll see that on occasion. But I would probably call this sebaceoma, without thinking it's sort of synonymous with sebaceous epithelium. Now, is there any condition you have to worry about with these? With any",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'sebaceoma', 'concept_id': 'C1275210', 'confidence': 1.0}, {'entity': 'basal cell carcinoma', 'concept_id': 'C0007117', 'confidence': 1.0}, {'entity': 'sebaceous differentiation', 'concept_id': 'C1882988', 'confidence': 1.0}], [{'entity': 'Sebaceomas', 'concept_id': 'C1275210', 'confidence': 0.8855459690093994}, {'entity': 'small', 'concept_id': 'C0700321', 'confidence': 0.9999998807907104}, {'entity': 'round', 'concept_id': 'C0332490', 'confidence': 1.0}, {'entity': 'skin-colored', 'concept_id': 'C4476819', 'confidence': 0.8005288243293762}], [{'entity': 'Basal cell carcinoma', 'concept_id': 'C0007117', 'confidence': 1.0}, {'entity': 'sebaceous differentiation', 'concept_id': 'C1882988', 'confidence': 1.0}, {'entity': 'clefting', 'concept_id': 'C4021813', 'confidence': 0.8906428217887878}, {'entity': 'palisading', 'concept_id': 'C1622240', 'confidence': 0.8684062361717224}, {'entity': 'sebaceous differentiation', 'concept_id': 'C1882988', 'confidence': 1.0}], [{'entity': 'conditions', 'concept_id': 'C0012634', 'confidence': 0.8556983470916748}, {'entity': 'concern', 'concept_id': 'C2699424', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_415",
"caption_rating": "8"
},
{
"": "1007092",
"caption": "Maintained polarity, nuclei reaching the middle third of the cells, and no prominent nuclei are criteria for low grade dysplasia.",
"image_path": "r7OA0Trj5hQ_image_40c0cfb7-5819-4248-b6e8-43ea19f9d42c.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['nuclei reaching the middle third of the cells', 'cells touching the top', 'maintained polarity', 'nuclei reaching the middle third of the cells', 'prominent nuclei', 'cells touching the top', 'nuclei running in different directions', 'maintained polarity', 'nuclei reaching the middle third of the cells', 'prominent nuclei', 'cells touching the top', 'nuclei running in different directions']",
"noisy_text": " is the maintained polarity, nuclei reaching the middle third of the cells, no prominent nuclei, cribriformic or micropapillary. This is the criteria for low grade dysplasia. Compare it with here. Here the cells are coming and touching the top. Can you all see the nuclei touching the top of the apical membrane? And see the prominent nuclei. And see the nuclei are running in different directions. This nuclei is running in this direction, whereas this nuclei is running in this direction. This nuclei is running in this direction. So there is loss of",
"corrected_text": " is the maintained polarity, nuclei reaching the middle third of the cells, no prominent nuclei, cribriform or micropapillary. This is the criteria for low grade dysplasia. Compare it with here. Here the cells are coming and touching the top. Can you all see the nuclei touching the top of the apical membrane? And see the prominent nuclei. And see the nuclei are running in different directions. This nuclei is running in this direction, whereas this nuclei is running in this direction. This nuclei is running in this direction. So there is loss of",
"med_umls_ids": "[[{'entity': 'Maintained', 'concept_id': 'C1314677', 'confidence': 1.0}, {'entity': 'polarity', 'concept_id': 'C0596963', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'middle', 'concept_id': 'C0227972', 'confidence': 1.0}, {'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'criteria', 'concept_id': 'C0243161', 'confidence': 0.9999998807907104}, {'entity': 'low', 'concept_id': 'C0205251', 'confidence': 0.9999999403953552}], [{'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'area', 'concept_id': 'C0017446', 'confidence': 1.0}, {'entity': 'top', 'concept_id': 'C1420726', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'directions', 'concept_id': 'C0439755', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_416",
"caption_rating": "9"
},
{
"": "1004932",
"caption": "Pathognomonic findings for lipodermatosclerosis.",
"image_path": "hoV-JkD6Wb0_image_2e6ed1f2-9837-44ad-b695-2071a6947a39.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['large fat microcysts', 'membranous lipodystrophy', 'fibrosis', 'lipophages', 'plasma cells', 'lipophages']",
"noisy_text": " ruptured and fused, and so we've got these large fat microcysts, and if we look at the periphery of the fat microcyst, we've got this lipomembranous change, this kind of arabesque-type fibular material out at the periphery, which basically represents coalescence of remnant cell walls of adipocytes. In addition, within the surrounding tissue, there's a little bit of fibrosis. There are a few lipophages and a very sparse infiltrative lymphocytes, and in this case, a few plasma cells, and of course, these findings are virtually pathognomonic for lipodermatosclerosis, especially in this clinical setting. Personally, in my practice, I see a lot more biopsies",
"corrected_text": " ruptured and fused, and so we've got these large fat microcysts, and if we look at the periphery of the fat microcyst, we've got this lipomembranous change, this kind of arabesque-type fibular material out at the periphery, which basically represents coalescence of remnant cell walls of adipocytes. In addition, within the surrounding tissue, there's a little bit of fibrosis. There are a few lipophages and a very sparse infiltrative lymphocytes, and in this case, a few plasma cells, and of course, these findings are pathognomonic for lipodermatosclerosis, especially in this clinical setting. Personally, in my practice, I see a lot more biopsies",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'fat microcysts', 'concept_id': 'C1513269', 'confidence': 0.871767520904541}, {'entity': 'membranous lipodystrophy', 'concept_id': 'C0406599', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'coalescence', 'concept_id': 'C4727092', 'confidence': 0.8749340176582336}, {'entity': 'remnant', 'concept_id': 'C3272697', 'confidence': 1.0}, {'entity': 'cell walls', 'concept_id': 'C0007623', 'confidence': 1.0}, {'entity': 'adipocytes', 'concept_id': 'C0206131', 'confidence': 1.0}], [{'entity': 'Fibrosis', 'concept_id': 'C0016059', 'confidence': 1.0}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}], [{'entity': 'Pathognomonic findings', 'concept_id': 'C2986472', 'confidence': 0.7794376611709595}, {'entity': 'lipodermatosclerosis', 'concept_id': 'C0406500', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_417",
"caption_rating": "8"
},
{
"": "1004748",
"caption": "Identification of squamous epithelium and gastric cardiac type of epithelium at the gastroesophageal junction.",
"image_path": "r7OA0Trj5hQ_image_5f54ce10-dac2-4f67-9d3f-86fec3c42d30.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Gastroesophageal junction with irregularly sized and shaped glands and variation in distribution.', 'Gastroesophageal junction with irregularly sized and shaped glands and variation in distribution.']",
"noisy_text": " metaplasia or dysplasia, either low-grade or high-grade. So this is a squamous epithelium. This is a gastric cardiac type of epithelium. So this is a gastroesophageal junction. Here you can see nice bifitting. And see the glands are not uniformly distributed. Variation in size. Some glands are small, some glands are large. And these glands are not branching normally, but you can see a nice bifitting. So these are all features of chronicity. Irregular size, shape, distribution means chronicity. Please remember, presence of lymphocytes and plasma cells is not a",
"corrected_text": " metaplasia or dysplasia, either low-grade or high-grade. So this is a squamous epithelium. This is a gastric cardiac type of epithelium. So this is a gastroesophageal junction. Here you can see nice bifitting. And see the glands are not uniformly distributed. Variation in size. Some glands are small, some glands are large. And these glands are not branching normally, but you can see a nice bifitting. So these are all features of chronicity. Irregular size, shape, distribution means chronicity. Please remember, presence of lymphocytes and plasma cells is not a",
"med_umls_ids": "[[{'entity': 'Identification', 'concept_id': 'C0020792', 'confidence': 1.0}, {'entity': 'squamous epithelium', 'concept_id': 'C0221909', 'confidence': 1.0}, {'entity': 'gastric cardiac type', 'concept_id': 'C0524600', 'confidence': 0.7429378628730774}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'gastroesophageal junction', 'concept_id': 'C0014871', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'irregularly', 'concept_id': 'C0425589', 'confidence': 0.905201256275177}, {'entity': 'sized', 'concept_id': 'C0600244', 'confidence': 0.8308623433113098}, {'entity': 'shaped glands', 'concept_id': 'C0332479', 'confidence': 0.7275685667991638}, {'entity': 'variation', 'concept_id': 'C0205419', 'confidence': 1.0}, {'entity': 'distribution', 'concept_id': 'C0037775', 'confidence': 1.0}, {'entity': 'chronicity', 'concept_id': 'C0547045', 'confidence': 1.0}], [{'entity': 'Importance', 'concept_id': 'C4086513', 'confidence': 0.96006178855896}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_418",
"caption_rating": "9"
},
{
"": "1009324",
"caption": "Possible low-grade fibromyxoid sarcoma based on fibrous and myxoid features with cellular and less cellular areas.",
"image_path": "QDb68_G1HR4_image_c54801e8-0700-41d9-ae67-c9e5f371599b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " here that is to me the low power clue, the red flag that says wait, could I be dealing with a low grade fibromyxoid sarcoma? Fibrous pink stuff mingled with pale blue myxoid stuff and more cellular areas like this intermingled with less cellular areas. Those features right there always make me think I have to exclude low grade fibromyxoid sarcoma with some practice and hopefully after this video, you'll have seen enough cases that you can start to recognize there are some very distinct features I think that at higher power that are kind",
"corrected_text": " here that is to me the low power clue, the red flag that says wait, could I be dealing with a low grade fibromyxoid sarcoma? Fibrous pink stuff mingled with pale blue myxoid stuff and more cellular areas like this intermingled with less cellular areas. Those features right there always make me think I have to exclude low grade fibromyxoid sarcoma with some practice and hopefully after this video, you'll have seen enough cases that you can start to recognize there are some very distinct features I think that at higher power that are kind",
"med_umls_ids": "[[{'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}, {'entity': 'myxoid', 'concept_id': 'C0205295', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'cellular', 'concept_id': 'C0007634', 'confidence': 0.9999999403953552}, {'entity': 'cellular areas', 'concept_id': 'C0007634', 'confidence': 0.7882957458496094}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_419",
"caption_rating": "8"
},
{
"": "1007337",
"caption": "The tissue sample shows a spectrum of histologic changes that can make diagnosis challenging.",
"image_path": "sDFjOtMAYrk_image_875f7281-a2ed-4bbb-9162-9b43f78f36bb.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['neutrophils and lymphocytes', 'neutrophils and lymphocytes', 'plasma cells in the lamina propria', 'histiocytes in the lamina propria']",
"noisy_text": " neutrophils and lymphocytes. And some cases have predominantly plasma cells in the lamina propria. Some cells have predominantly histiocytes in the lamina propria. I used to think when we started recognizing these that all of the cases look the same, but we've learned in the past couple of years that there's a spectrum of histologic changes that can make it really challenging. The good thing about this case is we do have the immuno at Hopkins. Immuno will be negative in the vast majority of these cases, but once in a while you'll catch one positive case. And this is one of those. I",
"corrected_text": " neutrophils and lymphocytes. And some cases have predominantly plasma cells in the lamina propria. Some cells have predominantly histiocytes in the lamina propria. I used to think when we started recognizing these that all of the cases look the same, but we've learned in the past couple of years that there's a spectrum of histologic changes that can make it really challenging. The good thing about this case is we do have the immuno at Hopkins. Immuno will be negative in the vast majority of these cases, but once in a while you'catch one positive case. And this is one of those. I",
"med_umls_ids": "[[{'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'spectrum', 'concept_id': 'C1883073', 'confidence': 1.0}, {'entity': 'histologic', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'changes', 'concept_id': 'C0392747', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'immuno test', 'concept_id': 'C0021061', 'confidence': 0.7767297029495239}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_420",
"caption_rating": "7"
},
{
"": "1008767",
"caption": "The first area is a branch of the mesenteric vein, while the second area is a branch of the mesenteric artery.",
"image_path": "r7OA0Trj5hQ_image_7031ca2a-b0a8-4ed6-b945-acfea1fed920.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Internal elastic lamina in one area', 'Branch of mesenteric artery', 'Branch of mesenteric vein', 'Idiopathic myointimal hyperplasia of mesenteric vein', 'Internal elastic lamina in one area', 'Branch of mesenteric artery', 'Branch of mesenteric vein', 'Idiopathic myointimal hyperplasia of mesenteric vein']",
"noisy_text": " And you can see here, there is no internal elastic lamina, whereas here, there is an internal elastic lamina. So this is a branch of mesenteric artery, whereas this is a branch of mesenteric vein. And there is a condition called as idiopathic myointimal hyperplasia of the mesenteric vein. I don't know how many of you have heard this company. There's a company called His Master's Voice, which we call HMV before, His Master's Voice. This dog is listening to the master's voice here. And another funny question there, is this dog male or female? Because it is His Master's Voice, it is male. I know it is not pathology, but talking up too",
"corrected_text": " And you can see here, there is no internal elastic lamina, whereas here, there is an internal elastic lamina. So this is a branch of mesenteric artery, whereas this is a branch of mesenteric vein. And there is a condition called as idiopathic myointimal hyperplasia of mesenteric vein of the mesenteric vein. I don't know how many of you have heard this company. There's a company called His Master's Voice, which we call HMV before, His Master's Voice. This dog is listening to the master's voice here. And another funny question there, is this dog male or female? Because it is His Master's Voice, it is male. I know it is not pathology, but talking up too",
"med_umls_ids": "[[{'entity': 'internal elastic lamina', 'concept_id': 'C1180561', 'confidence': 1.0}, {'entity': 'area', 'concept_id': 'C0017446', 'confidence': 1.0}, {'entity': 'internal elastic lamina', 'concept_id': 'C1180561', 'confidence': 1.0}, {'entity': 'area', 'concept_id': 'C0017446', 'confidence': 1.0}], [{'entity': 'area', 'concept_id': 'C0017446', 'confidence': 1.0}, {'entity': 'branch', 'concept_id': 'C0205384', 'confidence': 1.0}, {'entity': 'mesenteric vein', 'concept_id': 'C0025473', 'confidence': 1.0}, {'entity': 'area', 'concept_id': 'C0017446', 'confidence': 1.0}, {'entity': 'branch', 'concept_id': 'C0205384', 'confidence': 1.0}, {'entity': 'mesenteric artery', 'concept_id': 'C0025465', 'confidence': 1.0}], [{'entity': 'Idiopathic myointimal hyperplasia', 'concept_id': 'C0333978', 'confidence': 0.8139097094535828}, {'entity': 'mesenteric vein', 'concept_id': 'C0025473', 'confidence': 1.0}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_421",
"caption_rating": "8"
},
{
"": "1004558",
"caption": "Stromal nodule of BPH can be extensive and lead to glands over 100 grams, sometimes even over 200 grams.",
"image_path": "iklRyY1nBIE_image_f5a5e0b7-dda1-40a2-ab09-a7a76b1e6691.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['Stromal nodule of BPH.']",
"noisy_text": " Not unusual to find some inflammation. So this is just a stromal nodule of BPH. I've seen cases in which, I've gotten cases over the years where, in a TRP specimen, or even a simple prostatectomy, where some of those cases, you can look at 10 slides with no glands at all, just the stromal component. And sometimes, the consulting pathologists may be very worried that, is this a lyomyoma, or is this a stump, or what exactly is going on? So sometimes, it's important to know that you can have a stromal nodule of BPH that is very extensive, and which obviously lead to glands that are over 100 grams. Some even, I've seen over 200 gram prostates that have extensive stromal proliferation. But one should not confuse that with stump. So I just thought I'll make that point quickly. So that's just a stromal nodule of BPH there. And then, I think I have another one. Right, so this is another one right here, a different case. But same",
"corrected_text": " Not unusual to find some inflammation. So this is just a stromal nodule of BPH. I've seen cases in which, I've gotten cases over the years where, in a TRP specimen, or even a simple prostatectomy, where some of those cases, you can look at 10 slides with no glands at all, just the stromal component. And sometimes, the consulting pathologists may be very worried that, is this a leiomyoma, or is this a stump, or what exactly is going on? So sometimes, it's important to know that you can have a stromal nodule of BPH that is very extensive, and which obviously lead to glands that are over 100 grams. Some even, I've seen over 200 gram prostates that have extensive stromal proliferation. But one should not confuse that with stump. So I just thought I'll make that point quickly. So that's just a stromal nodule of BPH there. And then, I think I have another one. Right, so this is another one right here, a different case. But same",
"med_umls_ids": "[[{'entity': 'Stromal nodule', 'concept_id': 'C0334485', 'confidence': 0.7674687504768372}, {'entity': 'BPH', 'concept_id': 'C0005001', 'confidence': 1.0}, {'entity': 'extensive', 'concept_id': 'C0205231', 'confidence': 1.0}, {'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}], [{'entity': 'stromal nodule', 'concept_id': 'C0334485', 'confidence': 0.7674687504768372}, {'entity': 'BPH', 'concept_id': 'C0005001', 'confidence': 1.0}, {'entity': 'stump', 'concept_id': 'C0002690', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_422",
"caption_rating": "8"
},
{
"": "1008094",
"caption": "The lesion shows a collection of dilated vascular spaces lined by plump endothelial cells with papillary projections, indicating a vascular neoplasm with a biphasic pattern.",
"image_path": "8S4LeiO6Bbk_image_687a667d-4611-4701-80e7-060ba6be0411.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['dilated vascular spaces', 'plump endothelial cells', 'papillary projections', 'extravasated erythrocytes']",
"noisy_text": " we can see that in the central portion of the lesion, we've got a collection of vascular spaces that are quite large or dilated. Many of these are lined by very plump kind of epithelioid or hobnailed endothelial cells, and some of them contain papillary projections that extend into the limina. If you look around, you can see these papillary projections. There are a few extravasated erythrocytes present within the stroma. So clearly, we've got this vascular neoplasma here with these dilated endothelial line spaces, but it's got kind of a bifasic pattern. Centrally, we've got these dilated vessels, but peripheral and beneath that zone, the vessels are somewhat more compressed. They're still lined by some of the plump endothelial cells. And in these various",
"corrected_text": " we can see that in the central portion of the lesion, we've got a collection of vascular spaces that are quite large or dilated. Many of these are lined by very plump kind of epithelioid or hobnailed endothelial cells, and some of them contain papillary projections that extend into the limina. If you look around, you can see these papillary projections. There are a few extravasated erythrocytes present within the stroma. So clearly, we've got this vascular neoplasm here with these dilated endothelial line spaces, but it's got kind of a biphasic pattern. Centrally, we've got these dilated vessels, but peripheral and beneath that zone, the vessels are somewhat more compressed. They're still lined by some of the plump endothelial cells. And in these various",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'collection', 'concept_id': 'C0600644', 'confidence': 1.0}, {'entity': 'dilated', 'concept_id': 'C0700124', 'confidence': 0.9999999403953552}, {'entity': 'vascular spaces', 'concept_id': 'C0225983', 'confidence': 0.819495439529419}, {'entity': 'plump', 'concept_id': 'C1836543', 'confidence': 0.7694027423858643}, {'entity': 'papillary projections', 'concept_id': 'C0016538', 'confidence': 0.7451471090316772}, {'entity': 'vascular neoplasm', 'concept_id': 'C0027668', 'confidence': 1.0}, {'entity': 'biphasic pattern', 'concept_id': 'C1332555', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_423",
"caption_rating": "9"
},
{
"": "1007770",
"caption": "Muscularization of the lamina propria is a criterion for mucosal prolapse in colon, particularly in solitary rectal ulcer syndrome.",
"image_path": "r7OA0Trj5hQ_image_f29d9f96-bd76-4216-bc52-b759ac8f6415.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['muscularization of the lamina propria', 'gastric mucosa', 'chemical gastritis', 'antral biopsy', 'inflammation', 'muscularization of the lamina propria', 'gastric mucosa', 'chemical gastritis', 'antral biopsy', 'inflammation']",
"noisy_text": " and in cases of mucosal prolapse in colon. Remember that solitary rectal ulcer syndrome, which is totally misnomer. It is neither solitary, can be seen in other parts other than rectum. There may not be any ulcer, there is no syndrome. So the whole solitary rectal ulcer syndrome is a misnomer. But muscularization of the lamina propria is one of the criteria for mucosal prolapse that is happening in solitary rectal ulcer syndrome. And this is a gastric mucosa. Here when you see muscularization of the lamina propria, you have to think of chemical gastritis. Will it form surface changes? Lamina propria edema and muscularis mucosa coming into the lamina propria. These are the three criterias. When you see it in the anterobiopsy, think of chemical gastritis that can be seen in biliary reflux or NSAID use. Lot of inflammation results. Remember I",
"corrected_text": " and in cases of mucosal prolapse in colon. Remember that solitary rectal ulcer syndrome, which is totally misnomer. It is neither solitary, can be seen in other parts other than rectum. There may not be any ulcer, there is no syndrome. So the whole solitary rectal ulcer syndrome is a misnomer. But muscularization of the lamina propria is one of the criteria for mucosal prolapse that is happening in solitary rectal ulcer syndrome. And this is a gastric mucosa. Here when you see muscularization of the lamina propria, you have to think of chemical gastritis. Will it form surface changes? Lamina propria edema and muscularis mucosa coming into the lamina propria. These are the three criteria. When you see it in the endoscopic biopsy, think of chemical gastritis that can be seen in biliary reflux or NSAID use. Lot of inflammation results. Remember I",
"med_umls_ids": "[[{'entity': 'Muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'criterion', 'concept_id': 'C0243161', 'confidence': 1.0}, {'entity': 'mucosal prolapse', 'concept_id': 'C0034888', 'confidence': 0.826268196105957}, {'entity': 'colon', 'concept_id': 'C0009368', 'confidence': 1.0}, {'entity': 'solitary rectal ulcer syndrome', 'concept_id': 'C4274343', 'confidence': 0.9999999403953552}], [{'entity': 'Muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'gastric mucosa', 'concept_id': 'C0017136', 'confidence': 1.0}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}, {'entity': 'biliary reflux', 'concept_id': 'C0232483', 'confidence': 0.7931289672851562}, {'entity': 'NSAID', 'concept_id': 'C0003211', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_424",
"caption_rating": "9"
},
{
"": "1007630",
"caption": "The presence of more than five neutrophils or more than 15 eosinophils per high power field in the lamina propria is indicative of eosinophilic gastritis, esophagitis, enteritis, or colitis.",
"image_path": "r7OA0Trj5hQ_image_e7c27242-cbd6-4dcd-9835-a28dd29ffa63.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Cryptitis', 'Crypt abscess', 'Variation in gland size, shape, and distribution.']",
"noisy_text": " Remember I told you if you see more than five neutrophils, more than five eosinophils sitting in the lamina propria or more than 15 eosinophils per high power field, that is a eosinophilic gastritis, if it is from the stomach. If it is esophagus, it is eosinophilic esophagitis, eosinophilic entritis, eosinophilic colitis. So eosinophilic gastroenteritis. Here it is a cryptitis and cryptopsis. And the glands are also pushed well apart. The glands are showing variation in size, shape, distribution. So this is chronic colitis with activity.",
"corrected_text": " Remember I told you if you see more than five neutrophils, more than five eosinophils sitting in the lamina propria or more than 15 eosinophils per high power field, that is a eosinophilic gastritis, if it is from the stomach. If it is esophagus, it is eosinophilic esophagitis, eosinophilic enteritis, eosinophilic colitis. So eosinophilic gastroenteritis. Here it is a cryptitis and crypt abscess. And the glands are also pushed well apart. The glands are showing variation in size, shape, distribution. So this is chronic colitis with activity.",
"med_umls_ids": "[[{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'eosinophilic gastritis', 'concept_id': 'C0267154', 'confidence': 1.0}, {'entity': 'esophagitis', 'concept_id': 'C0014868', 'confidence': 1.0}, {'entity': 'enteritis', 'concept_id': 'C0014335', 'confidence': 1.0}, {'entity': 'colitis', 'concept_id': 'C0009319', 'confidence': 1.0}], [{'entity': 'cryptitis', 'concept_id': 'C1394254', 'confidence': 0.9999998807907104}, {'entity': 'crypt', 'concept_id': 'C1880192', 'confidence': 1.0}, {'entity': 'abscess', 'concept_id': 'C0000833', 'confidence': 1.0}, {'entity': 'inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}, {'entity': 'area', 'concept_id': 'C0017446', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_425",
"caption_rating": "9"
},
{
"": "1004310",
"caption": "The tissue has myxoid features with very fine delicate collagen.",
"image_path": "QDb68_G1HR4_image_72696061-bdf2-437c-a2ee-0049bbeeccaa.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['myxoid features', 'fine delicate collagen', 'cellular intramuscular myxoma', 'fibrous areas', 'cellular areas', 'MUC4 stain']",
"noisy_text": " Here's again the myxoid background I really think this is very helpful. The very very fine delicate collagen that you see. Now areas like this I think can kind of resemble what you see in a so-called cellular intramuscular myxoma. Intramuscular myxomas are usually very blue and myxoid very hypocellular but sometimes they get more fibrous and more cellular areas. And on a needle biopsy I think that can be challenging. So I think usually with some experience you can tell them apart on H and E most of the time but when I have any doubt I just do a MUC4 stain. The MUC4 is negative and on a needle it looks like a myxoma with some kind of fibrous or a little bit more cellular areas and then I just say that it's probably a cellular intramuscular myxoma. So I think MUC4",
"corrected_text": " Here's again the myxoid background I really think this is very helpful. The very very fine delicate collagen that you see. Now areas like this I think can kind of resemble what you see in a so-called cellular intramuscular myxoma. Intramuscular myxomas are usually very blue and myxoid very hypocellular but sometimes they get more fibrous and more cellular areas. And on a needle biopsy I think that can be challenging. So I think usually with some experience you can tell them apart on H and E most of the time but when I have any doubt I just do a MUC4 stain. The MUC4 is negative and on a needle it looks like a myxoma with some kind of fibrous or a little bit more cellular areas and then I just say that it's probably a cellular intramuscular myxoma. So I think MUC4",
"med_umls_ids": "[[{'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'myxoid', 'concept_id': 'C0205295', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}], [{'entity': 'narrator', 'concept_id': 'C1135957', 'confidence': 0.7711340188980103}, {'entity': 'cellular', 'concept_id': 'C0007634', 'confidence': 0.9999999403953552}, {'entity': 'intramuscular', 'concept_id': 'C0442117', 'confidence': 1.0}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}, {'entity': 'cellular areas', 'concept_id': 'C0007634', 'confidence': 0.7882957458496094}], [{'entity': 'MUC4', 'concept_id': 'C1417496', 'confidence': 0.9999999403953552}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'confirm', 'concept_id': 'C0521093', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'cellular intramuscular myxoma', 'concept_id': 'C1334260', 'confidence': 0.8910117149353027}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_426",
"caption_rating": "8"
},
{
"": "1006122",
"caption": "Giant cells are larger and more numerous in another example of this tumor.",
"image_path": "j_rG5XPImFQ_image_5c9a737a-56a2-4890-a545-1645d40ff13e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Hematopathology', 'Breast pathology']",
"roi_text": "['multilobulated growth', 'dense fibrosis', 'giant cells', 'multilobulated growth', 'dense fibrosis', 'giant cells']",
"noisy_text": " Mitotic activity can be relatively high, but this on its own should not be concerning for malignant transformation. In this case, you could see that the giant cells were not numerous, and there was minimal hemosiderin deposition. To give you a better sense of the morphologic spectrum of this tumor, I'm going to show a couple more examples. In this example, we still have multilobulated growth and dense fibrosis. However, even at low power, you can see that the giant cells are larger and more numerous than the previous example.",
"corrected_text": " Mitotic activity can be relatively high, but this on its own should not be concerning for malignant transformation. In this case, you could see that the giant cells were not numerous, and there was minimal hemosiderin deposition. To give you a better sense of the morphologic spectrum of this tumor, I'm going to show a couple more examples. In this example, we still have multilobulated growth and dense fibrosis. However, even at low power, you can see that the giant cells are larger and more numerous than the previous example.",
"med_umls_ids": "[[{'entity': 'Mitotic activity', 'concept_id': 'C1334779', 'confidence': 1.0}, {'entity': 'malignant transformation', 'concept_id': 'C0287850', 'confidence': 0.8324378132820129}], [{'entity': 'Giant cells', 'concept_id': 'C0017526', 'confidence': 1.0}, {'entity': 'hemosiderin', 'concept_id': 'C0019113', 'confidence': 1.0}, {'entity': 'deposition', 'concept_id': 'C0333562', 'confidence': 1.0}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}], [{'entity': 'Multilobulated', 'concept_id': 'C4538849', 'confidence': 0.8302288055419922}, {'entity': 'growth', 'concept_id': 'C0018270', 'confidence': 1.0}, {'entity': 'dense fibrosis', 'concept_id': 'C0016059', 'confidence': 0.8111783862113953}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}], [{'entity': 'Giant cells', 'concept_id': 'C0017526', 'confidence': 1.0}, {'entity': 'larger', 'concept_id': 'C0549177', 'confidence': 1.0}, {'entity': 'numerous', 'concept_id': 'C0439064', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_427",
"caption_rating": "7"
},
{
"": "1004857",
"caption": "Collections of immune cells are present throughout the dermis, surrounded by a narrow cuff of mononuclear cells.",
"image_path": "hoV-JkD6Wb0_image_12fbbe53-4b6b-44c3-b6aa-ff4f21a71e8b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['ectatic vessels', 'papillary dermis', 'perivascular infiltrate of lymphocytes', 'collections of immune cells', 'narrow cuff of mononuclear cells']",
"noisy_text": " and we'll take a look at two of them, you had to review similar findings, bisected punch. And as expected, there are ectatic vessels here. Let me tilt the slide here. And the papillary dermis, a little bit of pallor consistent with edema, a little bit of a perivascular infiltrate of lymphocytes. And then present throughout the dermis, there are a few collections of epithelioid histiocytes. Here, there's one right there. And down here, we have another collection of epithelioid histiocytes. These are surrounded by a narrow cuff of mononuclear cells, but many",
"corrected_text": " and we'll take a look at two of them, you had to review similar findings, bisected punch. And as expected, there are ectatic vessels here. Let me tilt the slide here. And the papillary dermis, a little bit of pallor consistent with edema, a little bit of a perivascular infiltrate of lymphocytes. And then present throughout the dermis, there are a few collections of epithelioid histiocytes. Here, there's one right there. And down here, we have another collection of epithelioid histiocytes. These are surrounded by a narrow cuff of mononuclear cells, but many",
"med_umls_ids": "[[{'entity': 'Ectatic vessels', 'concept_id': 'C0005847', 'confidence': 0.7720959186553955}, {'entity': 'papillary dermis', 'concept_id': 'C0682598', 'confidence': 1.0}, {'entity': 'pallor', 'concept_id': 'C0030232', 'confidence': 1.0}, {'entity': 'consistent with', 'concept_id': 'C0332290', 'confidence': 1.0}, {'entity': 'edema', 'concept_id': 'C0013604', 'confidence': 0.9999999403953552}, {'entity': 'perivascular', 'concept_id': 'C0442165', 'confidence': 1.0}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}], [{'entity': 'Collections', 'concept_id': 'C0600644', 'confidence': 0.8663196563720703}, {'entity': 'immune cells', 'concept_id': 'C4330475', 'confidence': 0.8268961906433105}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'surrounded', 'concept_id': 'C1282914', 'confidence': 1.0}, {'entity': 'cuff', 'concept_id': 'C0441107', 'confidence': 1.0}, {'entity': 'mononuclear cells', 'concept_id': 'C0806987', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_428",
"caption_rating": "9"
},
{
"": "1005287",
"caption": "The sample is stratified and shows cribriform and micropapillary process.",
"image_path": "r7OA0Trj5hQ_image_02a9f76c-0858-4d40-868a-9163d61564ef.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['nuclei touching the top of the apical membrane', 'prominent nuclei', 'loss of cellular polarity', 'cribriform', 'micropapillary process']",
"noisy_text": " Can you all see the nuclei touching the top of the apical membrane? And see the prominent nuclei. And see the nuclei are running in different directions. This nuclei is running in this direction, whereas this nuclei is running in this direction. This nuclei is running in this direction. So there is loss of polarity. Okay, so here also it is stratified, reaching up to the top, and it is showing loss of polarity. And see the cribriformic. And this is a micropapillary process. Since it's a high power, you are not able to appreciate it better. I will show it to you in the other pictures. But here",
"corrected_text": " Can you all see the nuclei touching the top of the apical membrane? And see the prominent nuclei. And see the nuclei are running in different directions. This nuclei is running in this direction, whereas this nuclei is running in this direction. This nuclei is running in this direction. So there is loss of cellular polarity. Okay, so here also it is stratified, reaching up to the top, and it is showing loss of cellular polarity. And see the cribriform. And this is a micropapillary process. Since it's a high power, you are not able to appreciate it better. I will show it to you in the other pictures. But here",
"med_umls_ids": "[[{'entity': 'Loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'cellular polarity', 'concept_id': 'C0085304', 'confidence': 1.0}, {'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}], [{'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'stratified', 'concept_id': 'C0205363', 'confidence': 1.0}, {'entity': 'cribriform', 'concept_id': 'C1621425', 'confidence': 0.9999999403953552}, {'entity': 'micropapillary process', 'concept_id': 'C1290608', 'confidence': 0.763504683971405}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_429",
"caption_rating": "8"
},
{
"": "1005542",
"caption": "Differentiation between mucinous and serous tumors based on the type of cells lining them. Mucinous tumors are lined with tall columnar mucin-filled cells, while serous tumors are lined with ciliated cuboidal cells. Mucinous cyst adenomas are characterized by a single lining of columnar cells without invasion or atypia, while mucinous borderline tumors show atypia and stratification but no invasion.",
"image_path": "3mRB9j0eyVM_image_b289fe3b-bcf1-4b76-bf2c-bb602f02cdad.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gynecologic', 'Hematopathology', 'Soft tissue']",
"roi_text": "['Tall columnar mucin-filled cells lining mucinous tumors', 'Mucinous cyst adenomas', 'Mucinous borderline ovarian tumors', 'Mucin-filled ovarian gross picture']",
"noisy_text": " Number two on the histological finding the cells here these are different from that of the cells of the serous tumors. We said that the serous cells that are cuboidal and they are ciliated cells, ciliated cuboidal type of cells these are lining these line the serous tumors whereas in case of mucinous tumors we see that the cells that are lining the mucinous tumors are tall columnar cells, here you can see tall columnar mucin filled cells. So this is the difference between mucinous and the serous tumors and all other things same that we call these as mucinous cyst adenomas when there is single lining of these columnar cells they line the cystic structures and they do not show invasion, they do not show atypia you will say that this is mucinous cyst adenoma. And you will say the mucinous borderline tumor when these lining cells they show atypia they show stratification yet they do not show invasion. So we call these as mucinous borderline tumors and for see this is the gross picture of mucinous borderline tumors, this is mucin filled ovarian structure of",
"corrected_text": " Number two on the histological finding the cells here these are different from that of the cells of the serous tumors. We said that the serous cells that are cuboidal and they are ciliated cells, ciliated cuboidal type of cells these are lining these line the serous tumors whereas in case of mucinous tumors we see that the cells that are lining the mucinous tumors are tall columnar cells, here you can see tall columnar mucin filled cells. So this is the difference between mucinous and the serous tumors and all other things same that we call these as mucinous cyst adenomas when there is single lining of these columnar cells they line the cystic structures and they do not show invasion, they do not show atypia you will say that this is mucinous cyst adenoma. And you will say the mucinous borderline tumor when these lining cells they show atypia they show stratification yet they do not show invasion. So we call these as mucinous borderline tumors and for see this is the gross picture of mucinous borderline tumors, this is mucin filled ovarian structure of",
"med_umls_ids": "[[{'entity': 'Differentiation', 'concept_id': 'C0007589', 'confidence': 1.0}, {'entity': 'mucinous', 'concept_id': 'C1513712', 'confidence': 0.9999999403953552}, {'entity': 'serous tumors', 'concept_id': 'C0027651', 'confidence': 0.7801989912986755}, {'entity': 'type of cells lining', 'concept_id': 'C0449475', 'confidence': 0.8227900862693787}, {'entity': 'Mucinous tumors', 'concept_id': 'C1334811', 'confidence': 0.8854840993881226}, {'entity': 'tall', 'concept_id': 'C4021875', 'confidence': 0.7256414890289307}, {'entity': 'serous tumors', 'concept_id': 'C0027651', 'confidence': 0.7801989912986755}, {'entity': 'ciliated cuboidal cells', 'concept_id': 'C0935440', 'confidence': 0.8498250842094421}, {'entity': 'Mucinous cyst adenomas', 'concept_id': 'C0010635', 'confidence': 0.8866450190544128}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'lining', 'concept_id': 'C0205132', 'confidence': 1.0}, {'entity': 'columnar cells', 'concept_id': 'C0225338', 'confidence': 1.0}, {'entity': 'invasion', 'concept_id': 'C1269955', 'confidence': 1.0}, {'entity': 'atypia', 'concept_id': 'C0741302', 'confidence': 0.9999999403953552}, {'entity': 'mucinous borderline tumors', 'concept_id': 'C0334365', 'confidence': 0.9327916502952576}, {'entity': 'atypia', 'concept_id': 'C0741302', 'confidence': 0.9999999403953552}, {'entity': 'stratification', 'concept_id': 'C1514983', 'confidence': 1.0}, {'entity': 'invasion', 'concept_id': 'C1269955', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "960.0",
"id": "test_430",
"caption_rating": "9"
},
{
"": "1005724",
"caption": "Neutrophils in the epithelium indicate cryptitis, which may be related to H. pylori infection.",
"image_path": "r7OA0Trj5hQ_image_48a6d84f-804f-417e-8a21-0d4a0136ba79.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Neutrophils in the epithelium indicating cryptitis', 'Gastric biopsy for H. pylori with crypt abscess']",
"noisy_text": " Please remember, presence of lymphocytes and plasma cells is not a feature of chronicity. But architectural change by the way of irregular size, shape, and distributed glands is an indication of chronicity. Criteria for chronicity. Yeah, you see nicely neutrophils sitting in the epithelium. Can you all see neutrophils sitting in the epithelium? So this is cryptitis. It is stomach, even though I'm using the term. But I just want to know whether you are able to understand or not. This is a gastric biopsy where you have to look for H. pylori because the H. pylori secrete some chemotactic factors for neutrophils. That's why the neutrophils come. And this is a crypt abscess. This is",
"corrected_text": " Please remember, presence of lymphocytes and plasma cells is not a feature of chronicity. But architectural change by the way of irregular size, shape, and distributed glands is an indication of chronicity. Criteria for chronicity. Yeah, you see nicely neutrophils sitting in the epithelium. Can you all see neutrophils sitting in the epithelium? So this is cryptitis. It is stomach, even though I'm using the term. But I just want to know whether you are able to understand or not. This is a gastric biopsy where you have to look for H. pylori because the H. pylori secrete some chemotactic factors for neutrophils. That's why the neutrophils come. And this is a crypt abscess. This is",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'chronicity', 'concept_id': 'C0547045', 'confidence': 1.0}, {'entity': 'architectural', 'concept_id': 'C0003737', 'confidence': 0.8758222460746765}, {'entity': 'changes', 'concept_id': 'C0392747', 'confidence': 1.0}, {'entity': 'gland size', 'concept_id': 'C0426336', 'confidence': 0.8790121674537659}, {'entity': 'shape', 'concept_id': 'C0332479', 'confidence': 1.0}, {'entity': 'distribution', 'concept_id': 'C0037775', 'confidence': 1.0}, {'entity': 'chronicity', 'concept_id': 'C0547045', 'confidence': 1.0}], [{'entity': 'Neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'cryptitis', 'concept_id': 'C1394254', 'confidence': 0.9999998807907104}, {'entity': 'H. pylori infection', 'concept_id': 'C0850666', 'confidence': 0.9999999403953552}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_431",
"caption_rating": "8"
},
{
"": "1005664",
"caption": "Pyloric gland metaplasia can be seen in colitis, end-associated injury, and mycophenol-associated injury.",
"image_path": "sDFjOtMAYrk_image_214d2a70-69d1-4660-9b43-434241da4ecc.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['Pyloric gland metaplasia']",
"noisy_text": " It's really dramatic, right? And not only that, what else do we have? Yeah, these cells, these glands right here. What is it? Yeah, exactly. It's a pyloric glomeruloplasia. So pyloric glomeruloplasia should be Crohn's. No, you can see pyloric glomeruloplasia in your sort of a colitis and end-associated injury and also in microphenol-associated injury, as this case is. And the tip of the patient is a solid organ transplant recipient. with microphenol-associated injury have many more in the way of eosinophils, a lot more in the way of eosinophils than GVHD patients do. So that's really, really helpful. Is there",
"corrected_text": " It's really dramatic, right? And not only that, what else do we have? Yeah, these cells, these glands right here. What is it? Yeah, exactly. It's a pyloric gland metaplasia. So pyloric gland metaplasia should be Crohn's. No, you can see pyloric gland metaplasia in your sort of a colitis and end-associated injury and also in mycophenol-associated injury, as this case is. And the tip of the patient is a solid organ transplant recipient. with mycophenol-associated injury have many more in the way of eosinophils, a lot more in the way of eosinophils than GVHD patients do. So that's really, really helpful. Is there",
"med_umls_ids": "[[{'entity': 'Pyloric gland', 'concept_id': 'C0227239', 'confidence': 1.0}, {'entity': 'metaplasia', 'concept_id': 'C0025568', 'confidence': 1.0}, {'entity': 'colitis', 'concept_id': 'C0009319', 'confidence': 1.0}, {'entity': 'end-associated injury', 'concept_id': 'C0552509', 'confidence': 0.6716579794883728}, {'entity': 'mycophenol-associated injury', 'concept_id': 'C0552509', 'confidence': 0.6023857593536377}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'solid organ transplant', 'concept_id': 'C0730400', 'confidence': 1.0}, {'entity': 'recipient', 'concept_id': 'C1709854', 'confidence': 1.0}, {'entity': 'mycophenol-associated injury', 'concept_id': 'C0552509', 'confidence': 0.6023857593536377}], [{'entity': 'Mycophenol-associated injury', 'concept_id': 'C0552509', 'confidence': 0.6023857593536377}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'GVHD', 'concept_id': 'C0018133', 'confidence': 1.0}, {'entity': 'patients', 'concept_id': 'C0030705', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_432",
"caption_rating": "9"
},
{
"": "1005444",
"caption": "Myositis ossificans is a benign myofibroblastic neoplasm that is part of the USP6 rearranged family of tumors.",
"image_path": "j_rG5XPImFQ_image_6da69d48-a359-4580-bf7d-0ccdf5b83e5b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Hematopathology', 'Breast pathology']",
"roi_text": "['nucleolus', 'myofibroblasts', 'myositis ossificans']",
"noisy_text": " nucleolus, and a moderate amount of amphiphilic cytoplasm. Now, at first glance, you might think these cells look a bit weird, and that might make you worry about a sarcoma, such as osteosarcoma. However, you'll come to recognize that this pattern in morphology you see here is really characteristic of myofibroblasts. This is an example of myocytosocificans, a benign myofibroblastic neoplasm that is part of the USP6 rearranged family of tumors, which includes, among others, nodular fasciitis and aneurysmal bone cyst. These are",
"corrected_text": " nucleolus, and a moderate amount of amphiphilic cytoplasm. Now, at first glance, you might think these cells look a bit weird, and that might make you worry about a sarcoma, such as osteosarcoma. However, you'll come to recognize that this pattern in morphology you see here is really characteristic of myofibroblasts. This is an example of myositis ossificans, a benign myofibroblastic neoplasm that is part of the USP6 rearranged family of tumors, which includes, among others, nodular fasciitis and aneurysmal bone cyst. These are",
"med_umls_ids": "[[{'entity': 'Moderate', 'concept_id': 'C0205081', 'confidence': 1.0}, {'entity': 'amount', 'concept_id': 'C1265611', 'confidence': 0.9999998807907104}, {'entity': 'amphiphilic', 'concept_id': 'C0596084', 'confidence': 0.8564908504486084}, {'entity': 'cytoplasm', 'concept_id': 'C0010834', 'confidence': 1.0}], [{'entity': 'Characteristic', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}, {'entity': 'myofibroblasts', 'concept_id': 'C0225360', 'confidence': 1.0}], [{'entity': 'Myositis ossificans', 'concept_id': 'C0027122', 'confidence': 0.9999999403953552}, {'entity': 'benign', 'concept_id': 'C0205183', 'confidence': 1.0}, {'entity': 'USP6', 'concept_id': 'C1175888', 'confidence': 1.0}, {'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_433",
"caption_rating": "9"
},
{
"": "1008435",
"caption": "Needle biopsy before excision allows for diagnosis and pre-treatment, but can wipe out original morphology.",
"image_path": "pBR26SS0FX8_image_decfa00c-795e-44d0-9da3-0464679a982a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Hematopathology', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " and not other parts of pathology where you have to calculate percent of key 67 staining and stuff. So anyway, I don't know if that's a good answer, but it's an honest one. Yeah, so the question brought up is that post treatment, once these tumors have been radiated, they usually, the vast majority of them just completely get wiped out. And all that's left is sclerotic collagen, a little bit of the vascular branchy stuff and mature adipocytes with occasional little tiny lipoblasts, maybe a few pockets of myxoid change. And if there was a round cell component, you'll never know because it usually gets wiped out and blasted by the radiation. So I agree, that's the problem. The trade-off is that doing the needle ahead of time to get the diagnosis on a needle biopsy allows you to make a diagnosis and pre-treat the tumor. The trade-off though, is that on the excision specimen, you'll really never probably know what the original morphology was like. And I feel like this is one of the trade-offs we've made in modern medicine, where there are benefits of having a needle biopsy before excision, a lot of benefits and probably more benefits than risks, but there are some downsides. And that's one of them is pre-treatment, wipes out the original morphology. But again, it's the main difference is the prognosis. The long-term prognosis is worse, unfortunately, for patients that have high-grade round cell morphology. And even though the low-grade myxoid liposarcoma, in the past, there was a thought that like, 90% of the patients were gonna be okay and 10% would get METs. But I think with longer follow-up, we started to see that a significantly larger number actually even of people with low-grade conventional myxoid liposarcoma will get metastases. I think the WHO says, I think their current quote is between 30 and it's more than 30%, I think. And different studies show different things so that even sometimes it's longer and farther out. Oh yeah, I forgot to mention, the other weird thing that you should know about myxoid liposarcoma, like all sarcomas, it will metastasize the lungs oftentimes. But it",
"corrected_text": " and not other parts of pathology where you have to calculate percent of key 67 staining and stuff. So anyway, I don't know if that's a good answer, but it's an honest one. Yeah, so the question brought up is that post treatment, once these tumors have been radiated, they usually, the vast majority of them just completely get wiped out. And all that's left is sclerotic collagen, a little bit of the vascular branching and mature adipocytes with occasional little tiny lipoblasts, maybe a few pockets of myxoid change. And if there was a round cell component, you'll never know because it usually gets wiped out and blasted by the radiation. So I agree, that's the problem. The trade-off is that doing the needle ahead of time to get the diagnosis on a needle biopsy allows you to make a diagnosis and pre-treat the tumor. The trade-off though, is that on the excision specimen, you'll really never probably know what the original morphology was like. And I feel like this is one of the trade-offs we've made in modern medicine, where there are benefits of having a needle biopsy before excision, a lot of benefits and probably more benefits than risks, but there are some downsides. And that's one of them is pre-treatment, wipes out the original morphology. But again, it's the main difference is the prognosis. The long-term prognosis is worse, unfortunately, for patients that have high-grade round cell morphology. And even though the low-grade myxoid liposarcoma, in the past, there was a thought that like, 90% of the patients were gonna be okay and 10% would get METs. But I think with longer follow-up, we started to see that a significantly larger number actually even of people with low-grade conventional myxoid liposarcoma will get metastases. I think the WHO says, I think their current quote is between 30 and it's more than 30%, I think. And different studies show different things so that even sometimes it's longer and farther out. Oh yeah, I forgot to mention, the other weird thing that you should know about myxoid liposarcoma, like all sarcomas, it will metastasize the lungs oftentimes. But it",
"med_umls_ids": "[[{'entity': 'Radiation treatment', 'concept_id': 'C1522449', 'confidence': 0.9999999403953552}, {'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'sclerotic', 'concept_id': 'C0036429', 'confidence': 0.9999999403953552}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'vascular branching', 'concept_id': 'C0005847', 'confidence': 0.7225151658058167}, {'entity': 'mature', 'concept_id': 'C0205286', 'confidence': 1.0}, {'entity': 'adipocytes', 'concept_id': 'C0206131', 'confidence': 1.0}, {'entity': 'lipoblasts', 'concept_id': 'C0225323', 'confidence': 0.8551441431045532}, {'entity': 'myxoid change', 'concept_id': 'C0205295', 'confidence': 0.815497636795044}], [{'entity': 'Needle biopsy', 'concept_id': 'C0005560', 'confidence': 1.0}, {'entity': 'excision', 'concept_id': 'C0015252', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'pre-treatment', 'concept_id': 'C0419819', 'confidence': 0.7933163046836853}, {'entity': 'original', 'concept_id': 'C0205313', 'confidence': 1.0}, {'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}], [{'entity': 'Prognosis', 'concept_id': 'C0033325', 'confidence': 1.0}, {'entity': 'patients', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'high-grade round cell', 'concept_id': 'C1512433', 'confidence': 0.7649602890014648}, {'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}], [{'entity': 'Low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'myxoid liposarcoma', 'concept_id': 'C0206634', 'confidence': 1.0}, {'entity': 'metastasize', 'concept_id': 'C0027627', 'confidence': 1.0}], [{'entity': 'Myxoid liposarcoma', 'concept_id': 'C0206634', 'confidence': 1.0}, {'entity': 'metastasize', 'concept_id': 'C0027627', 'confidence': 1.0}, {'entity': 'lungs', 'concept_id': 'C0024109', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_434",
"caption_rating": "7"
},
{
"": "1004607",
"caption": "Discussion of a possible diagnosis of IBD based on the presence of pannate cell metaplasia and distortion associated with a lymphoid aggregate in the preserved lamina propria.",
"image_path": "sDFjOtMAYrk_image_492b4ab0-41c2-412d-bad2-37ad9487aff4.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['distortion associated with a huge lymphoid aggregate', 'prominent lymphoid aggregates', 'pannate cell metaplasia']",
"noisy_text": " discuss further down the road. And then the last differential is this. All right. So, Emilio, what would you say about the architecture in this case? Yeah. And then in some areas, there's a little bit of distortion, but what's the distortion associated with? Yeah, a huge lymphoid aggregate. So, this case, as you move along, you'll see a couple of prominent lymphoid aggregates there, here, in the backdrop of preserved lamina propria. So, and then, okay, it might be IBD, especially because there's pannate cell metaplasia, and this is from the rectum. You see the pannate cell metaplasia is showing well?",
"corrected_text": " discuss further down the road. And then the last differential is this. All right. So, Emilio, what would you say about the architecture in this case? Yeah. And then in some areas, there's a little bit of distortion, but what's the distortion associated with? Yeah, a huge lymphoid aggregate. So, this case, as you move along, you'll see a couple of prominent lymphoid aggregates there, here, in the backdrop of preserved lamina propria. So, and then, okay, it might be IBD, especially because there's pannate cell metaplasia, and this is from the rectum. You see the pannate cell metaplasia is showing well?",
"med_umls_ids": "[[{'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'IBD', 'concept_id': 'C0021390', 'confidence': 1.0}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'pannate cell', 'concept_id': 'C0007634', 'confidence': 0.5671628713607788}, {'entity': 'distortion', 'concept_id': 'C0332482', 'confidence': 1.0}, {'entity': 'associated with', 'concept_id': 'C0332281', 'confidence': 1.0}, {'entity': 'lymphoid', 'concept_id': 'C1518071', 'confidence': 1.0}, {'entity': 'aggregate', 'concept_id': 'C0205418', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_435",
"caption_rating": "8"
},
{
"": "1008723",
"caption": "Extravasated erythrocytes, siderophages, and an infiltrate of lymphocytes are seen at the periphery.",
"image_path": "8S4LeiO6Bbk_image_7a1fbb54-1a16-4c4d-ba48-7199d6c67247.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['siderophages']",
"noisy_text": " by these dilated vascular channels. Let's look at the bottom piece, which frequently do contain these papillary projections, which protrude into the lumina, these plump endothelial cells, and then at the periphery, more compressed vascular channels, which dissect between collagen bundles. And it's at the periphery one frequently sees extravasated erythrocytes, siderophages, and an infiltrate of lymphocytes. So targetoid hemocidiotic hemangioma. Sometimes it can be quite difficult to distinguish these from patch gage stage Kaposi's. And again, HHV8 stain will help you because these are routinely negative for HHVA and the Kaposi's, of course, will always stain with an HHV8 stain. And we will close out our discussion with slide number 12, which is kind of a cool case to end on. And we have two pieces of tissue here. And if",
"corrected_text": " by these dilated vascular channels. Let's look at the bottom piece, which frequently do contain these papillary projections, which protrude into the lumina, these plump endothelial cells, and then at the periphery, more compressed vascular channels, which dissect between collagen bundles. And it's at the periphery one frequently sees extravasated erythrocytes, siderophages, and an infiltrate of lymphocytes. So targetoid hemosiderotic hemangioma. Sometimes it can be quite difficult to distinguish these from patch gage stage Kaposi's. And again, HHV8 stain will help you because these are routinely negative for HHVA and the Kaposi's, of course, will always stain with an HHV8 stain. And we will close out our discussion with slide number 12, which is kind of a cool case to end on. And we have two pieces of tissue here. And if",
"med_umls_ids": "[[{'entity': 'Dilated', 'concept_id': 'C0700124', 'confidence': 0.9999999403953552}, {'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}], [{'entity': 'Papillary projections', 'concept_id': 'C0016538', 'confidence': 0.7451471090316772}, {'entity': 'lumina', 'concept_id': 'C0524462', 'confidence': 0.845600426197052}], [{'entity': 'Enlarged endothelial cells', 'concept_id': 'C0423263', 'confidence': 0.7785332202911377}], [{'entity': 'Compressed vascular channels', 'concept_id': 'C1336948', 'confidence': 0.5993747711181641}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'bundles', 'concept_id': 'C3658308', 'confidence': 0.8706014752388}], [{'entity': 'Extravasated', 'concept_id': 'C0015376', 'confidence': 0.868863582611084}, {'entity': 'erythrocytes', 'concept_id': 'C0014772', 'confidence': 1.0}, {'entity': 'siderophages', 'concept_id': 'C1136253', 'confidence': 0.7251443266868591}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}], [{'entity': 'Targetoid hemosiderotic hemangioma', 'concept_id': 'C0346076', 'confidence': 0.9999999403953552}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'targetoid hemosiderotic hemangioma', 'concept_id': 'C0346076', 'confidence': 0.9999999403953552}, {'entity': \"patch stage Kaposi's\", 'concept_id': 'C0280201', 'confidence': 0.7629613280296326}], [{'entity': 'HHV8', 'concept_id': 'C0036220', 'confidence': 1.0}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_436",
"caption_rating": "9"
},
{
"": "1008750",
"caption": "Lamina propria is full of cells with a distinct cell border, abundant foamy cytoplasm, and centrally placed nucleus in gastric xanthoma.",
"image_path": "r7OA0Trj5hQ_image_8c27381b-ee6a-42e7-844a-c61938edde63.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['young males', 'inflammatory bowel disease', 'lamina propria', 'distinct cell border', 'foamy cytoplasm', 'centrally placed nucleus', 'gastric xanthoma', 'young males', 'inflammatory bowel disease', 'lamina propria', 'distinct cell border', 'foamy cytoplasm', 'centrally placed nucleus', 'gastric xanthoma']",
"noisy_text": " It is commonly seen in young males, and they present with the signs and symptoms of inflammatory bowel disease. Interesting condition. Here, the lamina propria is full of cells with a distinct cell border, abundant foamy cytoplasm, most of the time centrally placed nucleus. Sometimes it is pushed to the periphery. The central nuclear placement is very important for a diagnosis of xanthoma. For a signet cells, it will be predominantly peripherally pushed nucleus. And when you have doubt, you do a CD68, which will be strongly positive. And so this is a gastric xanthoma. Here, it",
"corrected_text": " It is commonly seen in young males, and they present with the signs and symptoms of inflammatory bowel disease. Interesting condition. Here, the lamina propria is full of cells with a distinct cell border, abundant foamy cytoplasm, most of the time centrally placed nucleus. Sometimes it is pushed to the periphery. The central nuclear placement is very important for a diagnosis of xanthoma. For a signet ring cells, it will be predominantly peripherally pushed nucleus. And when you have doubt, you do a CD68, which will be strongly positive. And so this is a gastric xanthoma. Here, it",
"med_umls_ids": "[[{'entity': 'Xanthoma', 'concept_id': 'C0302314', 'confidence': 1.0}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'young', 'concept_id': 'C0332239', 'confidence': 1.0}, {'entity': 'males', 'concept_id': 'C0086582', 'confidence': 1.0}, {'entity': 'signs', 'concept_id': 'C0220912', 'confidence': 0.9999999403953552}, {'entity': 'symptoms', 'concept_id': 'C0683368', 'confidence': 1.0}, {'entity': 'inflammatory bowel disease', 'concept_id': 'C0021390', 'confidence': 1.0}], [{'entity': 'Lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'cell border', 'concept_id': 'C0205284', 'confidence': 0.773768424987793}, {'entity': 'foamy cytoplasm', 'concept_id': 'C0010834', 'confidence': 0.7207725048065186}, {'entity': 'centrally', 'concept_id': 'C0205099', 'confidence': 0.7070305943489075}, {'entity': 'nucleus', 'concept_id': 'C0007610', 'confidence': 1.0}, {'entity': 'gastric xanthoma', 'concept_id': 'C1282522', 'confidence': 1.0}], [{'entity': 'CD68', 'concept_id': 'C0108799', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'xanthoma', 'concept_id': 'C0302314', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_437",
"caption_rating": "8"
},
{
"": "1008335",
"caption": "A biopsy showed that the lamina propria was not hyalinized, but recent ischemia cannot be excluded.",
"image_path": "sDFjOtMAYrk_image_c349f8b8-d567-4ceb-abc0-085ad1d06be2.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['lamina propria', 'pseudomembranes', 'ischemia', 'C. diff', 'lamina propria', 'pseudomembranes', 'ischemia', 'C. diff']",
"noisy_text": " will give you pseudomembranes. Ischemic injury can also give it to you. And the one thing to note is that, so this patient had C. difficile colitis by laboratory, but he was not responding to treatment and they just decided to take a biopsy. And you can see here that in the lamina propria is not hyalinized. Now, does that mean that ischemia is excluded? No, because if it's, you know, it depends on the clinical history. If it's recent ischemia that happened within, I don't know, 24, 48 hours, you know, the hyalinopropia may not have had time to hyalinize. How long does it take for the lamina propria to become pink? I don't know, but longer. So C. diff. Oh, another mimic of ischemia. And you can see why this mimics ischemia. The lamina propria is kind of pink and hyalinized. On top of that, there's actually some architectural distortion. This",
"corrected_text": " will give you pseudomembranes. Ischemic injury can also give it to you. And the one thing to note is that, so this patient had Clostridioides difficile colitis by laboratory, but he was not responding to treatment and they just decided to take a biopsy. And you can see here that in the lamina propria is not hyalinized. Now, does that mean that ischemia is excluded? No, because if it's, you know, it depends on the clinical history. If it's recent ischemia that happened within, I don't know, 24, 48 hours, you know, the hyalinopropia may not have had time to hyalinize. How long does it take for the lamina propria to become pink? I don't know, but longer. So C. diff. Oh, another mimic of ischemia. And you can see why this mimics ischemia. The lamina propria is kind of pink and hyalinized. On top of that, there's actually some architectural distortion. This",
"med_umls_ids": "[[{'entity': 'Pseudomembranes', 'concept_id': 'C0240821', 'confidence': 1.0}, {'entity': 'Clostridioides', 'concept_id': 'C4406271', 'confidence': 1.0}, {'entity': 'colitis', 'concept_id': 'C0009319', 'confidence': 1.0}, {'entity': 'ischemic injury', 'concept_id': 'C2945681', 'confidence': 0.8915668725967407}], [{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'hyalinized', 'concept_id': 'C0332230', 'confidence': 1.0}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}, {'entity': 'excluded', 'concept_id': 'C0332196', 'confidence': 1.0}], [{'entity': 'C. diff', 'concept_id': 'C0238106', 'confidence': 0.8398770093917847}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}, {'entity': 'pink', 'concept_id': 'C0332585', 'confidence': 1.0}, {'entity': 'hyalinized lamina propria', 'concept_id': 'C0332230', 'confidence': 0.7577076554298401}, {'entity': 'architectural changes', 'concept_id': 'C0003737', 'confidence': 0.7067119479179382}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_438",
"caption_rating": "9"
},
{
"": "1006860",
"caption": "The presence of lymphoid aggregates suggests diversion colitis, even if the patient does not have a Hartman\u2019s pouch.",
"image_path": "sDFjOtMAYrk_image_d2c14566-c857-49e5-9213-ae46e036c9ef.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['Architectural distortion', 'Prominent lymphoid aggregates', 'Paneth cell metaplasia']",
"noisy_text": " architectural distortion, prominent lymphoid aggregates and pan-at-cell metaplasia, C-note in the absence of any history, the differential diagnosis includes, you know, inflammatory bowel disease, com parenthesis quiescent, comma. I mean, because of the lymphoid aggregates, I would think about diversion colitis, knowing that this is from the rectum, even if I don't know that the patient has a Hartman's pouch. I would say infection is unlikely and medication probably unlikely. And for the first case, let's, sometimes we get the condition that give you just random colon and not have this. Just on the one, just on the one biopsy. Yeah. And then",
"corrected_text": " architectural distortion, prominent lymphoid aggregates and paneth cell metaplasia, note in the absence of any history, the differential diagnosis includes, you know, inflammatory bowel disease, com parenthesis quiescent, comma. I mean, because of the lymphoid aggregates, I would think about diversion colitis, knowing that this is from the rectum, even if I don't know that the patient has a Hartman's pouch. I would say infection is unlikely and medication probably unlikely. And for the first case, let's, sometimes we get the condition that give you just random colon and not have this. Just on the one, just on the one biopsy. Yeah. And then",
"med_umls_ids": "[[{'entity': 'Architectural distortion', 'concept_id': 'C2826609', 'confidence': 1.0}, {'entity': 'lymphoid', 'concept_id': 'C1518071', 'confidence': 1.0}, {'entity': 'aggregates', 'concept_id': 'C0205418', 'confidence': 1.0}, {'entity': 'Paneth', 'concept_id': 'C0227276', 'confidence': 0.7872004508972168}, {'entity': 'inflammatory bowel disease', 'concept_id': 'C0021390', 'confidence': 1.0}, {'entity': 'diversion colitis', 'concept_id': 'C0267532', 'confidence': 1.0}], [{'entity': 'Infection', 'concept_id': 'C0009450', 'confidence': 1.0}, {'entity': 'medication', 'concept_id': 'C0013227', 'confidence': 1.0}], [{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lymphoid', 'concept_id': 'C1518071', 'confidence': 1.0}, {'entity': 'aggregates', 'concept_id': 'C0205418', 'confidence': 1.0}, {'entity': 'diversion colitis', 'concept_id': 'C0267532', 'confidence': 1.0}, {'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'Hartman\u2019s pouch', 'concept_id': 'C0447546', 'confidence': 0.9055206179618835}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_439",
"caption_rating": "8"
},
{
"": "1007431",
"caption": "Mild degree of architectural distortion is present.",
"image_path": "sDFjOtMAYrk_image_f5e1c62e-602e-4f58-823f-8c8d482be39e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "[]",
"noisy_text": " they're receiving radiation, is a lot of eosinophils and even intracryptal eosinophilic microapses. You don't see a lot in the way of neutrophils. You may see some neutrophils in the cytoplasm of the nuclei, like intracellular intracytoplasmic neutrophils, but not really neutrophilic microapses. And the other thing you might see is intracytoplasmic vacuoles degenerating vacuoles. So, this is a good example of chemotherapy associated colitis, a mimic of inflammatory bowel disease. Oh, this is a good one. With that degree, the mild degree of architectural distortion is what's making me fall short of saying this is for sure IBD. So, I would be descriptive and I would say, you know,",
"corrected_text": " they're receiving radiation, is a lot of eosinophils and even intracryptal eosinophilic microapses. You don't see a lot in the way of neutrophils. You may see some neutrophils in the cytoplasm of the nuclei, like intracellular intracytoplasmic neutrophils, but not really neutrophilic microapses. And the other thing you might see is intracytoplasmic vacuoles degenerating vacuoles. So, this is a good example of chemotherapy associated colitis, a mimic of inflammatory bowel disease. Oh, this is a good one. With that degree, the mild degree of architectural distortion is what's making me fall short of saying this is for sure IBD. So, I would be descriptive and I would say, you know,",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'intracryptal', 'concept_id': 'C3315370', 'confidence': 0.626490592956543}, {'entity': 'microapses', 'concept_id': 'C0700712', 'confidence': 0.5626617074012756}, {'entity': 'patients', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'radiation', 'concept_id': 'C0034519', 'confidence': 1.0}], [{'entity': 'intracellular', 'concept_id': 'C0175996', 'confidence': 1.0}, {'entity': 'intracytoplasmic', 'concept_id': 'C0230649', 'confidence': 0.8670988082885742}, {'entity': 'neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'degenerating', 'concept_id': 'C0011164', 'confidence': 1.0}, {'entity': 'vacuoles', 'concept_id': 'C0042219', 'confidence': 1.0}], [{'entity': 'Chemotherapy', 'concept_id': 'C0013216', 'confidence': 1.0}, {'entity': 'colitis', 'concept_id': 'C0009319', 'confidence': 1.0}, {'entity': 'inflammatory bowel disease', 'concept_id': 'C0021390', 'confidence': 1.0}], [{'entity': 'Mild', 'concept_id': 'C1513302', 'confidence': 1.0}, {'entity': 'degree', 'concept_id': 'C0441889', 'confidence': 1.0}, {'entity': 'architectural distortion', 'concept_id': 'C2826609', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_440",
"caption_rating": "8"
},
{
"": "1008328",
"caption": "The patient is a solid organ transplant recipient with mycophenol-associated injury, which typically has more eosinophils than GVHD.",
"image_path": "sDFjOtMAYrk_image_7ba03594-d61b-4022-b5a1-5bc3ff58a9de.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['pyloric gland metaplasia', 'solid organ transplant recipient', 'eosinophils', 'pyloric gland metaplasia', 'solid organ transplant recipient', 'eosinophils']",
"noisy_text": " Yeah, these cells, these glands right here. What is it? Yeah, exactly. It's a pyloric glomeruloplasia. So pyloric glomeruloplasia should be Crohn's. No, you can see pyloric glomeruloplasia in your sort of a colitis and end-associated injury and also in microphenol-associated injury, as this case is. And the tip of the patient is a solid organ transplant recipient. with microphenol-associated injury have many more in the way of eosinophils, a lot more in the way of eosinophils than GVHD patients do. So that's really, really helpful. Is there",
"corrected_text": " Yeah, these cells, these glands right here. What is it? Yeah, exactly. It's a pyloric gland metaplasia. So pyloric gland metaplasia should be Crohn's. No, you can see pyloric gland metaplasia in your sort of a colitis and end-associated injury and also in mycophenol-associated injury, as this case is. And the tip of the patient is a solid organ transplant recipient. with mycophenol-associated injury have many more in the way of eosinophils, a lot more in the way of eosinophils than GVHD patients do. So that's really, really helpful. Is there",
"med_umls_ids": "[[{'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'image', 'concept_id': 'C1696103', 'confidence': 1.0}, {'entity': 'pyloric gland metaplasia', 'concept_id': 'C4288813', 'confidence': 1.0}, {'entity': 'colitis', 'concept_id': 'C0009319', 'confidence': 1.0}, {'entity': 'end-associated injury', 'concept_id': 'C0552509', 'confidence': 0.6716579794883728}, {'entity': 'mycophenol-associated injury', 'concept_id': 'C0552509', 'confidence': 0.6023857593536377}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'solid organ transplant', 'concept_id': 'C0730400', 'confidence': 1.0}, {'entity': 'recipient', 'concept_id': 'C1709854', 'confidence': 1.0}, {'entity': 'mycophenol-associated injury', 'concept_id': 'C0552509', 'confidence': 0.6023857593536377}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'GVHD', 'concept_id': 'C0018133', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_441",
"caption_rating": "8"
},
{
"": "1008138",
"caption": "H. pylori can be best visualized with careful examination of H&E stain.",
"image_path": "r7OA0Trj5hQ_image_8f9043a7-50a3-4fa1-a6bd-1328b134b4ba.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Goblet cells in gastric mucosa', 'Peritoneal cells in the body of the stomach', 'Goblet cells in gastric mucosa', 'Peritoneal cells in the body of the stomach']",
"noisy_text": " So the best stain for H. pylori is careful examination of H&E. Here H&E picture showing goblet cells in a gastric mucosa. The goblet cells are taking blue color, in algean blue, whereas the gastric epithelium is taking the PAS color. So this is algean blue PAS, intersternal metaplasia of the gastric mucosa. Here the history is this biopsy is taken from the body of the stomach. In the body of the stomach, you have to see a lot of fried eggs. These are all the peritoneal cells in addition to mucincycletine cells and chief cells. These are the peritoneal cells. When you",
"corrected_text": " So the best stain for H. pylori is careful examination of H&E. Here H&E picture showing goblet cells in a gastric mucosa. The goblet cells are taking blue color, in Alcian blue, whereas the gastric epithelium is taking the PAS color. So this is Alcian blue PAS, intestinal metaplasia of the gastric mucosa. Here the history is this biopsy is taken from the body of the stomach. In the body of the stomach, you have to see a lot of fried eggs. These are all the peritoneal cells in addition to mucincycletine cells and chief cells. These are the peritoneal cells. When you",
"med_umls_ids": "[[{'entity': 'H. pylori', 'concept_id': 'C0079488', 'confidence': 1.0}, {'entity': 'visualized', 'concept_id': 'C0234621', 'confidence': 1.0}, {'entity': 'examination', 'concept_id': 'C0031809', 'confidence': 1.0}, {'entity': 'H&E stain', 'concept_id': 'C0523207', 'confidence': 1.0}], [{'entity': 'image', 'concept_id': 'C1696103', 'confidence': 1.0}, {'entity': 'goblet cells', 'concept_id': 'C0506994', 'confidence': 0.9999999403953552}, {'entity': 'gastric mucosa', 'concept_id': 'C0017136', 'confidence': 1.0}, {'entity': 'blue color', 'concept_id': 'C1260957', 'confidence': 1.0}, {'entity': 'Alcian blue', 'concept_id': 'C0001933', 'confidence': 1.0}, {'entity': 'PAS', 'concept_id': 'C0030125', 'confidence': 1.0}, {'entity': 'color', 'concept_id': 'C0009393', 'confidence': 1.0}, {'entity': 'gastric epithelium', 'concept_id': 'C0227208', 'confidence': 1.0}], [{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'body', 'concept_id': 'C0227230', 'confidence': 1.0}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'peritoneal cells', 'concept_id': 'C0031153', 'confidence': 0.7749612331390381}, {'entity': 'mucincycletine cells', 'concept_id': 'C0007586', 'confidence': 0.6177586317062378}, {'entity': 'chief cells', 'concept_id': 'C1516470', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_442",
"caption_rating": "7"
},
{
"": "1008363",
"caption": "There are discrete columns and mounds of parakeratosis within the stratum corneum and some dyskeratotic cells within the underlying epidermis.",
"image_path": "8S4LeiO6Bbk_image_525c93d7-23ef-4276-b0ce-6a5662640cb6.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['columns and mounds of parakeratosis within the stratum corneum', 'dyskeratotic cells within the underlying epidermis', 'papillary dermis between these zones', 'no identifiable foam cells present within the papillary dermis', 'columns and mounds of parakeratosis within the stratum corneum', 'dyskeratotic cells within the underlying epidermis', 'papillary dermis between these zones', 'no identifiable foam cells present within the papillary dermis']",
"noisy_text": " and if we move to higher power, we can confirm these findings. Lymphocytes, dilated vessels, papillomatosis, and epidermal hyperplasia. There are discrete columns and mounds of pericaratosis within the stratum corneum and some dyskeratotic cells within the underlying epidermis. One of the things when one sees these these columns of bright pink pericaratosis that one might think about would be a verruciform xanthoma because you'll remember we tend to get these vertical columns of pericaratosis kind of extending down to a v-shaped imagination of the epidermis. We have that here but one thing that we don't have here that one typically sees in a verruciform xanthoma is the presence of neutrophils and mixed with the pericaratotic cells and also if we look in the dermal papillae between these zones, there are really no identifiable foam cells present within the dermal papillae. Looking over at the far edge of this",
"corrected_text": " and if we move to higher power, we can confirm these findings. Lymphocytes, dilated vessels, papillomatosis, and epidermal hyperplasia. There are discrete columns and mounds of parakeratosis within the stratum corneum and some dyskeratotic cells within the underlying epidermis. One of the things when one sees these these columns of bright pink parakeratosis that one might think about would be a verruciform xanthoma because you'remember we tend to get these vertical columns of pericaratosis kind of extending down to a v-shaped imagination of the epidermis. We have that here but one thing that we don't have here that one typically sees in a verruciform xanthoma is the presence of neutrophils and mixed with the parakeratotic cells and also if we look in the dermal papillae between these zones, there are really no identifiable foam cells present within the dermal papillae. Looking over at the far edge of this",
"med_umls_ids": "[[{'entity': 'histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'findings', 'concept_id': 'C2607943', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'dilated vessels', 'concept_id': 'C0424830', 'confidence': 0.8255378603935242}, {'entity': 'papillomatosis', 'concept_id': 'C0205875', 'confidence': 1.0}, {'entity': 'epidermal hyperplasia', 'concept_id': 'C0263641', 'confidence': 1.0}], [{'entity': 'discrete columns', 'concept_id': 'C0227428', 'confidence': 0.6879350543022156}, {'entity': 'mounds', 'concept_id': 'C2717795', 'confidence': 0.736616313457489}, {'entity': 'parakeratosis', 'concept_id': 'C0030436', 'confidence': 1.0}, {'entity': 'stratum corneum', 'concept_id': 'C0221921', 'confidence': 1.0}, {'entity': 'dyskeratotic cells', 'concept_id': 'C1512098', 'confidence': 0.8970272541046143}, {'entity': 'epidermis', 'concept_id': 'C0014520', 'confidence': 1.0}], [{'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'foam cells', 'concept_id': 'C0016390', 'confidence': 1.0}, {'entity': 'verruciform xanthoma', 'concept_id': 'C0346054', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_443",
"caption_rating": "9"
},
{
"": "1007270",
"caption": "Infected histiocytes with organisms of this size in the cytoplasm may indicate histoplasmosis or leishmaniasis.",
"image_path": "hoV-JkD6Wb0_image_ab334dab-d7fe-4b97-96ee-cfba68daa86b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['histiocytes']",
"noisy_text": " one to two microns. And we can use our erythrocyte here as kind of a ruler. Most erythrocytes and lymphocytes have nuclei that have diameters about five to six microns. And so you can see that these round organisms at the periphery of the histiocytes are about one to two microns. And as you'll see in a subsequent slide, when you see parasitized histiocytes with organisms of this size in the cytoplasm, you're either dealing with histoplasmosis or leishmaniasis. And of the two, leishmaniasis has a tendency to cluster at the periphery of the cell producing the so-called marquee sign",
"corrected_text": " one to two microns. And we can use our erythrocyte here as kind of a ruler. Most erythrocytes and lymphocytes have nuclei that have diameters about five to six microns. And so you can see that these round organisms at the periphery of the histiocytes are about one to two microns. And as you'll see in a subsequent slide, when you see infected histiocytes with organisms of this size in the cytoplasm, you're either dealing with histoplasmosis or leishmaniasis. And of the two, leishmaniasis has a tendency to cluster at the periphery of the cell producing the socalled marquee sign",
"med_umls_ids": "[[{'entity': 'Round organisms', 'concept_id': 'C0029235', 'confidence': 0.813967227935791}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'microns', 'concept_id': 'C0439201', 'confidence': 0.9999999403953552}, {'entity': 'diameter', 'concept_id': 'C1301886', 'confidence': 1.0}], [{'entity': 'Infected', 'concept_id': 'C0439663', 'confidence': 1.0}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'organisms', 'concept_id': 'C0029235', 'confidence': 0.9999998807907104}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'cytoplasm', 'concept_id': 'C0010834', 'confidence': 1.0}, {'entity': 'histoplasmosis', 'concept_id': 'C0019655', 'confidence': 1.0}, {'entity': 'leishmaniasis', 'concept_id': 'C0023281', 'confidence': 1.0}], [{'entity': 'Leishmaniasis', 'concept_id': 'C0023281', 'confidence': 1.0}, {'entity': 'cluster', 'concept_id': 'C1555715', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'cell', 'concept_id': 'C0007634', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_444",
"caption_rating": "9"
},
{
"": "1004500",
"caption": "Nodules around joints can be seen in gout, RA, and OE.",
"image_path": "udoW6VSqsm4_image_aa82a88b-0c10-40be-a90f-a118b2d6c185.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " You notice this is on acral skin. There are often nodules in that area, and they can start off as palpable purpura in some cases. So, it's like, you know, regular leukocytoplastic vasculitis that can end up with these nodular lesions. Next slide. What is the histologic identical twin of this process? The granulomyphial. Yes, excellent. Granulomyphial looks very, very similar to this on the microscope. Obviously, clinically, it's not like this. It's on the face. It's on the pseudolymphoma. Next slide. So, this is a type of chronic vasculitis that ends up forming these fibrotic nodules. It's an interesting condition, and it is thought to be associated with other conditions. So, you want to make sure that you don't just, next case. A lot of times, these things can give you cholesterol clefts. One of the old names for this years ago used to be extracellular cholesterolosis, and it would give you these, all these neutrophils would gradually degranulate, if you will. The neutrophil products would have lipid in them, and you'd get these cholesterol clefts that would look kind of yellowish. Now, what are a couple other clinical diseases where you can see nodules around joints? You know, like, gout, RA, OE. Good. Gout, RA. There's",
"corrected_text": " You notice this is on acral skin. There are often nodules in that area, and they can start off as palpable purpura in some cases. So, it's like, you know, leukocytoclastic vasculitis that can end up with these nodular lesions. Next slide. What is the histologic identical twin of this process? The granuloma faciale. Yes, excellent. granuloma faciale looks very, very similar to this on the microscope. Obviously, clinically, it's not like this. It's on the face. It's on the pseudolymphoma. Next slide. So, this is a type of chronic vasculitis that ends up forming these fibrotic nodules. It's an interesting condition, and it is thought to be associated with other conditions. So, you want to make sure that you don't just, next case. A lot of times, these things can give you cholesterol clefts. One of the old names for this years ago used to be extracellular cholesterolosis, and it would give you these, all these neutrophils would gradually degranulate, if you will. The neutrophil products would have lipid in them, and you'd get these cholesterol clefts that would look kind of yellowish. Now, what are a couple other clinical diseases where you can see nodules around joints? You know, like, gout, RA, OE. Good. Gout, RA. There's",
"med_umls_ids": "[[{'entity': 'Nodules', 'concept_id': 'C0028259', 'confidence': 1.0}, {'entity': 'acral skin', 'concept_id': 'C0444099', 'confidence': 0.7122198939323425}, {'entity': 'leukocytoclastic vasculitis', 'concept_id': 'C0151436', 'confidence': 1.0}, {'entity': 'nodular', 'concept_id': 'C0205297', 'confidence': 1.0}, {'entity': 'lesions', 'concept_id': 'C0221198', 'confidence': 1.0}], [{'entity': 'Granuloma faciale', 'concept_id': 'C0239495', 'confidence': 1.0}, {'entity': 'histologic', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'identical', 'concept_id': 'C0205280', 'confidence': 1.0}, {'entity': 'twin', 'concept_id': 'C0041427', 'confidence': 0.9999999403953552}, {'entity': 'process', 'concept_id': 'C1184743', 'confidence': 1.0}], [{'entity': 'Granuloma faciale', 'concept_id': 'C0239495', 'confidence': 1.0}, {'entity': 'leukocytoclastic vasculitis', 'concept_id': 'C0151436', 'confidence': 1.0}, {'entity': 'microscope', 'concept_id': 'C0181839', 'confidence': 1.0}], [{'entity': 'Chronic vasculitis', 'concept_id': 'C0042384', 'confidence': 0.7992802858352661}, {'entity': 'fibrotic nodules', 'concept_id': 'C0332561', 'confidence': 0.8351579308509827}], [{'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'associated with', 'concept_id': 'C0332281', 'confidence': 1.0}, {'entity': 'conditions', 'concept_id': 'C0012634', 'confidence': 0.8556983470916748}], [{'entity': 'Extracellular cholesterolosis', 'concept_id': 'C2973528', 'confidence': 0.9169934391975403}, {'entity': 'cholesterol clefts', 'concept_id': 'C3686582', 'confidence': 0.9999999403953552}, {'entity': 'yellowish nodules', 'concept_id': 'C1867455', 'confidence': 0.8135299682617188}], [{'entity': 'Nodules', 'concept_id': 'C0028259', 'confidence': 1.0}, {'entity': 'joints', 'concept_id': 'C0022417', 'confidence': 1.0}, {'entity': 'gout', 'concept_id': 'C0018099', 'confidence': 1.0}, {'entity': 'RA', 'concept_id': 'C0002893', 'confidence': 1.0}, {'entity': 'OE', 'concept_id': 'C1551089', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_445",
"caption_rating": "8"
},
{
"": "1007020",
"caption": "Clinical description of a skin condition with small individual papules that have a central crust, often on perioral skin.",
"image_path": "udoW6VSqsm4_image_95719a02-3a3f-4588-8a77-58a6dc65c44c.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['small individual papules', 'central crust', 'perioral skin', 'granulomatous condition', 'palisade granulostermatitis', 'neutrophilic dermatosis', 'older individuals', 'perineoplastic process']",
"noisy_text": " Yeah, this would be more kind of the classic one, probably. What else? Here's the classic one clinically. What if there's small individual papules that have a central crust in them, often on apral skin? We have had several cases of the disseminated GA, but I'm not sure if they didn't have a crust. So, what's the type that had it? Perforating? Perforating GA. Perforating GA, good. So, this was granulomanuary. There's one other condition that gives you palisade granulostermatitis like this, but it also gives you some neutrophils infiltrate. That palisade and neutrophilic granulostermatitis, that's another thing that you at least have to think about when you see GA. If you see an older person that's got disseminated GA, think about it as a perineoplastic process. Sometimes you",
"corrected_text": " Yeah, this would be more kind of the classic one, probably. What else? Here's the classic one clinically. What if there's small individual papules that have a central crust in them, often on perioral skin? We have had several cases of the disseminated GA, but I'm not sure if they didn't have a crust. So, what's the type that had it? Perforating? Perforating GA. Perforating GA, good. So, this was granulomatous. There's one other condition that gives you palisade granulostermatitis like this, but it also gives you some neutrophils infiltrate. That palisade and neutrophilic dermatosis, that's another thing that you at least have to think about when you see GA. If you see an older person that's got disseminated GA, think about it as a perineoplastic process. Sometimes you",
"med_umls_ids": "[[{'entity': 'Clinical', 'concept_id': 'C0205210', 'confidence': 1.0}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'skin condition', 'concept_id': 'C1719933', 'confidence': 1.0}, {'entity': 'individual', 'concept_id': 'C0027361', 'confidence': 1.0}, {'entity': 'papules', 'concept_id': 'C0332563', 'confidence': 0.9999999403953552}, {'entity': 'central crust', 'concept_id': 'C0205204', 'confidence': 0.7633819580078125}, {'entity': 'perioral skin', 'concept_id': 'C0448802', 'confidence': 0.8075158596038818}], [{'entity': 'Perforating', 'concept_id': 'C0549099', 'confidence': 1.0}, {'entity': 'GA', 'concept_id': 'C0002915', 'confidence': 1.0}, {'entity': 'granulomatous condition', 'concept_id': 'C0439667', 'confidence': 0.8219265341758728}, {'entity': 'palisade', 'concept_id': 'C0331512', 'confidence': 0.8241410255432129}, {'entity': 'granulostermatitis', 'concept_id': 'C0743086', 'confidence': 0.7311265468597412}], [{'entity': 'Neutrophilic dermatosis', 'concept_id': 'C1142272', 'confidence': 1.0}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'GA', 'concept_id': 'C0002915', 'confidence': 1.0}], [{'entity': 'Disseminated', 'concept_id': 'C0205221', 'confidence': 1.0}, {'entity': 'GA', 'concept_id': 'C0002915', 'confidence': 1.0}, {'entity': 'older', 'concept_id': 'C0337524', 'confidence': 0.7771234512329102}, {'entity': 'individuals', 'concept_id': 'C0027361', 'confidence': 0.8766164779663086}, {'entity': 'perineoplastic process', 'concept_id': 'C0027671', 'confidence': 0.8771522045135498}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_446",
"caption_rating": "8"
},
{
"": "1007571",
"caption": "Muscularization of the lamina propria is a criterion for mucosal prolapse.",
"image_path": "r7OA0Trj5hQ_image_ee9486d9-d74a-4c27-815d-5c02fa6616ac.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['muscle', 'lamina propria', 'muscularis mucosa', 'chemical gastritis', 'mucosal prolapse', 'solitary rectal ulcer syndrome', 'muscle', 'lamina propria', 'muscularis mucosa', 'chemical gastritis', 'mucosal prolapse', 'solitary rectal ulcer syndrome']",
"noisy_text": " You see in the hyperwire, muscle coming in the lamina propria. Lamina propria should be free of musculature. The muscle should be there only in the muscularis mucosa. Here in this low power, you can see the muscularis mucosa is hyperplastic. And it is sending the muscle bundle into the lamina propria. This happens in chemical gastritis in case of stomach and in cases of mucosal prolapse in colon. Remember that solitary rectal ulcer syndrome, which is totally misnomer. It is neither solitary, can be seen in other parts other than rectum. There may not be any ulcer, there is no syndrome. So the whole solitary rectal ulcer syndrome is a misnomer. But muscularization of the lamina propria is one of the criteria for mucosal prolapse that is happening in",
"corrected_text": " You see in the hyperplasia, muscle coming in the lamina propria. Lamina propria should be free of musculature. The muscle should be there only in the muscularis mucosa. Here in this low power, you can see the muscularis mucosa is hyperplastic. And it is sending the muscle bundle into the lamina propria. This happens in chemical gastritis in case of stomach and in cases of mucosal prolapse in colon. Remember that solitary rectal ulcer syndrome, which is totally misnomer. It is neither solitary, can be seen in other parts other than rectum. There may not be any ulcer, there is no syndrome. So the whole solitary rectal ulcer syndrome is a misnomer. But muscularization of the lamina propria is one of the criteria for mucosal prolapse that is happening in",
"med_umls_ids": "[[{'entity': 'Muscle hyperplasia', 'concept_id': 'C2265913', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'abnormal', 'concept_id': 'C0205161', 'confidence': 1.0}, {'entity': 'muscularis mucosa', 'concept_id': 'C0225357', 'confidence': 0.9999998807907104}], [{'entity': 'Muscle bundles', 'concept_id': 'C0504095', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'hyperplasia', 'concept_id': 'C0020507', 'confidence': 1.0}, {'entity': 'muscularis mucosa', 'concept_id': 'C0225357', 'confidence': 0.9999998807907104}], [{'entity': 'Muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'criterion', 'concept_id': 'C0243161', 'confidence': 1.0}, {'entity': 'mucosal prolapse', 'concept_id': 'C0034888', 'confidence': 0.826268196105957}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_447",
"caption_rating": "8"
},
{
"": "1008343",
"caption": "The lesion is a small benign papule with dilated blood vessels and proliferating sebaceous lobules. It has two components: a fibrous component and an epithelial component, which includes an epithelial sebaceous gland.",
"image_path": "LlPaENuqzVQ_image_229ba3dc-e10d-4f65-bd84-2e49b4d79faf.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['dilated blood vessels', 'sebaceous lobules', 'fibrous component', 'epithelial component', 'epithelial sebaceous gland', 'teensy small follicle', 'dilated blood vessels', 'sebaceous lobules', 'fibrous component', 'epithelial component', 'epithelial sebaceous gland', 'teensy small follicle']",
"noisy_text": " And then there's some dilated blood vessels and whatnot, background sebaceous lobules that are proliferating. This may be kind of an incipient one of them, but this is what we're looking at here. So it's a small teensy tiny papule. And it's, if it's a neoplasm, it's got a two components to it. It's got a fibrous component, like right here. And then it's also got this epithelial component. What do you think this, what kind of differentiation are we looking at right here? Right, I feel it, right. So this is epithelial sebaceous gland. That's epithelium, little teensy small follicle right there. What's this? Is it closer to this or this? Sorry. Like, it",
"corrected_text": " And then there's some dilated blood vessels and whatnot, background sebaceous lobules that are proliferating. This may be kind of an incipient one of them, but this is what we're looking at here. So it's a small teensy tiny papule. And it's, if it's a neoplasm, it's got a two components to it. It's got a fibrous component, like right here. And then it's also got this epithelial component. What do you think this, what kind of differentiation are we looking at right here? Right, I feel it, right. So this is epithelial sebaceous gland. That's epithelium, little teensy small follicle right there. What's this? Is it closer to this or this? Sorry. Like, it",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'benign papule', 'concept_id': 'C0205183', 'confidence': 0.7019047737121582}, {'entity': 'dilated blood vessels', 'concept_id': 'C0424830', 'confidence': 1.0}, {'entity': 'proliferating sebaceous lobules', 'concept_id': 'C0221946', 'confidence': 0.7654090523719788}, {'entity': 'components', 'concept_id': 'C0449432', 'confidence': 1.0}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}, {'entity': 'epithelial component', 'concept_id': 'C1707933', 'confidence': 0.8783122897148132}, {'entity': 'epithelial sebaceous gland', 'concept_id': 'C0036505', 'confidence': 0.7906183004379272}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_448",
"caption_rating": "9"
},
{
"": "1008934",
"caption": "Muscularization of the lamina propria is a criterion for mucosal prolapse in colon, particularly in solitary rectal ulcer syndrome.",
"image_path": "r7OA0Trj5hQ_image_75b89890-3f6b-4df3-a664-1f7ee3c87a05.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['muscularization of the lamina propria', 'gastric mucosa', 'chemical gastritis', 'antral biopsy', 'inflammation', 'muscularization of the lamina propria', 'gastric mucosa', 'chemical gastritis', 'antral biopsy', 'inflammation', 'muscularization of the lamina propria', 'gastric mucosa', 'chemical gastritis', 'antral biopsy', 'inflammation']",
"noisy_text": " and in cases of mucosal prolapse in colon. Remember that solitary rectal ulcer syndrome, which is totally misnomer. It is neither solitary, can be seen in other parts other than rectum. There may not be any ulcer, there is no syndrome. So the whole solitary rectal ulcer syndrome is a misnomer. But muscularization of the lamina propria is one of the criteria for mucosal prolapse that is happening in solitary rectal ulcer syndrome. And this is a gastric mucosa. Here when you see muscularization of the lamina propria, you have to think of chemical gastritis. Will it form surface changes? Lamina propria edema and muscularis mucosa coming into the lamina propria. These are the three criterias. When you see it in the anterobiopsy, think of chemical gastritis that can be seen in biliary reflux or NSAID use. Lot of inflammation results. Remember I",
"corrected_text": " and in cases of mucosal prolapse in colon. Remember that solitary rectal ulcer syndrome, which is totally misnomer. It is neither solitary, can be seen in other parts other than rectum. There may not be any ulcer, there is no syndrome. So the whole solitary rectal ulcer syndrome is a misnomer. But muscularization of the lamina propria is one of the criteria for mucosal prolapse that is happening in solitary rectal ulcer syndrome. And this is a gastric mucosa. Here when you see muscularization of the lamina propria, you have to think of chemical gastritis. Will it form surface changes? Lamina propria edema and muscularis mucosa coming into the lamina propria. These are the three criteria. When you see it in the endoscopic biopsy, think of chemical gastritis that can be seen in biliary reflux or NSAID use. Lot of inflammation results. Remember I",
"med_umls_ids": "[[{'entity': 'Muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'criterion', 'concept_id': 'C0243161', 'confidence': 1.0}, {'entity': 'mucosal prolapse', 'concept_id': 'C0034888', 'confidence': 0.826268196105957}, {'entity': 'colon', 'concept_id': 'C0009368', 'confidence': 1.0}, {'entity': 'solitary rectal ulcer syndrome', 'concept_id': 'C4274343', 'confidence': 0.9999999403953552}], [{'entity': 'Muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'gastric mucosa', 'concept_id': 'C0017136', 'confidence': 1.0}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}, {'entity': 'biliary reflux', 'concept_id': 'C0232483', 'confidence': 0.7931289672851562}, {'entity': 'NSAID', 'concept_id': 'C0003211', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_449",
"caption_rating": "9"
},
{
"": "1008988",
"caption": "Bisected shape biopsy specimen with a dome-shaped papule from an acral site.",
"image_path": "8S4LeiO6Bbk_image_71432987-2a09-4988-8eee-3b9d4ec32094.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['dome-shaped papule', 'dome-shaped papule', 'acral site', 'thick stratum corneum', 'absence of hair follicles', 'fibrovascular core', 'nerve fascicles', 'spindle-shaped cells']",
"noisy_text": " can be quite impressive. Moving on to slide number 6. With slide number 6 we've got a bisected shape biopsy specimen. Now one of the useful clues to the diagnosis in this case is recognizing that we've got a dome-shaped papule and that the biopsy is from an acral site. Notice that we've got a very very thick stratum corneum and a marked to virtual absence of hair follicles within the specimen. We do have kind of this fibrovascular core and of course in the center of the fibrovascular core here we've got several well-defined nerve fascicles and the spindled cells characterizing these nerve",
"corrected_text": " can be quite impressive. Moving on to slide number 6. With slide number 6 we've got a bisected shape biopsy specimen. Now one of the useful clues to the diagnosis in this case is recognizing that we've got a dome-shaped papule and that the biopsy is from an acral site. Notice that we've got a very very thick stratum corneum and a marked to virtual absence of hair follicles within the specimen. We do have kind of this fibrovascular core and of course in the center of the fibrovascular core here we've got several well-defined nerve fascicles and the spindled cells characterizing these nerve",
"med_umls_ids": "[[{'entity': 'Bisected', 'concept_id': 'C0589437', 'confidence': 0.7404435873031616}, {'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'dome-shaped papule', 'concept_id': 'C1711316', 'confidence': 0.752353847026825}, {'entity': 'acral site', 'concept_id': 'C0439746', 'confidence': 0.717435359954834}], [{'entity': 'stratum corneum', 'concept_id': 'C0221921', 'confidence': 1.0}, {'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'hair follicles', 'concept_id': 'C0221971', 'confidence': 0.9999998807907104}, {'entity': 'specimen', 'concept_id': 'C0370003', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'fibrovascular', 'concept_id': 'C0392759', 'confidence': 1.0}, {'entity': 'core', 'concept_id': 'C0444669', 'confidence': 0.9999999403953552}, {'entity': 'nerve fascicles', 'concept_id': 'C1185741', 'confidence': 0.8332967758178711}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_450",
"caption_rating": "8"
},
{
"": "1005506",
"caption": "The size of the particles within the histiocytes is markedly variable.",
"image_path": "8S4LeiO6Bbk_image_c4c2c977-449a-4e37-906e-581095b3bd08.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Size of particles within histiocytes', 'Size of particles within histiocytes', 'Pigmented histiocytes with hemocyanin pigment', 'Extravasated erythrocytes', 'Size of particles within histiocytes']",
"noisy_text": " in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes as suspected is hemocentaurant. If you notice, it's got kind of that golden brown color. If you had a sub-stage condenser or a fine focus knob, you would see that it's somewhat refractile, but unfortunately, we can't use that particular tool when we're looking at scanned images. But one clue to the fact that we're dealing with hemocentaurant rather than melanin, not only is the presence of extravasated erythrocytes, but if you look at the size of the particles within the histiocytes, they're markedly variable. So the hemocentaurant is of course a breakdown product of the RBCs. And you can see that we've got small granules next to very large, chunky granules. Melanin pigment on the other hand, which of course can be found in melanophages or histiocytes containing the particles, the melanin granules tend to be more uniform in size. And of course, one can always do special stains, an iron stain, such as Prussian blue or pearls for hemocentaurant and a Fontanumus song stain for melanin pigment. So in any case, getting back to the to the lesion in question, we've got a lot of hemocentaurant-laden histiocytes here. We've also got, in other areas, fascicles, kind of randomly oriented of histiocytes and fibrocytes with oval",
"corrected_text": " in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes as suspected is hemocyanin. If you notice, it's got kind of that golden brown color. If you had a sub-stage condenser or a fine focus knob, you would see that it's somewhat refractile, but unfortunately, we can't use that particular tool when we're looking at scanned images. But one clue to the fact that we're dealing with hemocyanin rather than melanin, not only is the presence of extravasated erythrocytes, but if you look at the size of the particles within the histiocytes, they're markedly variable. So the hemocyanin is of course a breakdown product of the RBCs. And you can see that we've got small granules next to very large, chunky granules. Melanin pigment on the other hand, which of course can be found in melanophages or histiocytes containing the particles, the melanin granules tend to be more uniform in size. And of course, one can always do special stains, an iron stain, such as Prussian blue or pearls for hemocyanin and a Fontana-Masson stain for melanin pigment. So in any case, getting back to the to the lesion in question, we've got a lot of hemocyanin-laden histiocytes here. We've also got, in other areas, fascicles, kind of randomly oriented of histiocytes and fibrocytes with oval",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'pigment', 'concept_id': 'C0031911', 'confidence': 1.0}, {'entity': 'breakdown', 'concept_id': 'C0699900', 'confidence': 0.9999999403953552}, {'entity': 'product', 'concept_id': 'C1254351', 'confidence': 1.0}, {'entity': 'RBCs', 'concept_id': 'C0014792', 'confidence': 1.0}], [{'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'particles', 'concept_id': 'C0597177', 'confidence': 1.0}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'variable', 'concept_id': 'C0439828', 'confidence': 1.0}], [{'entity': 'Melanin', 'concept_id': 'C0025196', 'confidence': 1.0}, {'entity': 'pigment', 'concept_id': 'C0031911', 'confidence': 1.0}, {'entity': 'uniform', 'concept_id': 'C0205375', 'confidence': 1.0}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}], [{'entity': 'Special stains', 'concept_id': 'C0038128', 'confidence': 0.7105166912078857}, {'entity': 'Prussian blue', 'concept_id': 'C0060234', 'confidence': 1.0}, {'entity': 'Fontana-Masson', 'concept_id': 'C0060631', 'confidence': 0.9090515375137329}, {'entity': 'confirm', 'concept_id': 'C0521093', 'confidence': 1.0}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}, {'entity': 'pigment', 'concept_id': 'C0031911', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_451",
"caption_rating": "8"
},
{
"": "1005295",
"caption": "Cutaneous Crohns can have similar clinical presentation to sarcoidosis.",
"image_path": "udoW6VSqsm4_image_21d07b99-d98c-471e-abc9-857c7318fe6e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['Lesions around the A-web, the nose', 'Deeper nodular form of sarcoidosis']",
"noisy_text": " So, yeah, there's several other things you can do. We're doing ulcerative colitis with rosacea sometimes. Usually not this intense, but you can see it in rosacea also. So, we'll show the picture of this. So, this is a classic clinical. These are lesions around the A-web, the nose. Beautiful example. The deeper nodular form, the Dariae ruse type of sarcoid. The guy on the right is going to come over and plaque wipe the area. So, there are a lot of clinical manifestations of sarcoidosis. So, yeah, this is a beautiful example of that. Caneous Crohn's, that's why I was going to ask. Caneous Crohn's can look sort of like this, yeah. That would be the differential also. So, yeah, you think about that. Usually, you know, Balfour's and Rosenthal. Usually not quite this degree like you see here. This is really a great example of real sarcoid. But, obviously,",
"corrected_text": " So, yeah, there's several other things you can do. We're doing ulcerative colitis with rosacea sometimes. Usually not this intense, but you can see it in rosacea also. So, we'll show the picture of this. So, this is a classic clinical. These are lesions around the A-web, the nose. Beautiful example. The deeper nodular form, the Dariae ruse type of sarcoid. The guy on the right is going to come over and plaque wipe the area. So, there are a lot of clinical manifestations of sarcoidosis. So, yeah, this is a beautiful example of that. cutaneous Crohn's, that's why I was going to ask. cutaneous Crohn's can look sort of like this, yeah. That would be the differential also. So, yeah, you think about that. Usually, you know, Balfour's and Rosenthal. Usually not quite this degree like you see here. This is really a great example of sarcoidosis. But, obviously,",
"med_umls_ids": "[[{'entity': 'Ulcerative colitis', 'concept_id': 'C0009324', 'confidence': 1.0}, {'entity': 'rosacea', 'concept_id': 'C0035854', 'confidence': 1.0}, {'entity': 'lesions', 'concept_id': 'C0221198', 'confidence': 1.0}, {'entity': 'A-web', 'concept_id': 'C0282111', 'confidence': 0.5314000844955444}, {'entity': 'nose', 'concept_id': 'C0028429', 'confidence': 0.9999999403953552}], [{'entity': 'Sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'clinical manifestations', 'concept_id': 'C4231046', 'confidence': 0.9626281261444092}, {'entity': 'nodular form', 'concept_id': 'C0205297', 'confidence': 0.8008954524993896}, {'entity': 'Dariae ruse type', 'concept_id': 'C0332307', 'confidence': 0.5478090047836304}], [{'entity': 'Cutaneous Crohns', 'concept_id': 'C0221912', 'confidence': 0.5978212356567383}, {'entity': 'clinical presentation', 'concept_id': 'C4554564', 'confidence': 0.8858868479728699}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_452",
"caption_rating": "7"
},
{
"": "1008448",
"caption": "Glut-1 is usually negative in perineuriomas, but there are rare reports of positive staining in low-grade fibromyxoid sarcomas.",
"image_path": "QDb68_G1HR4_image_8772a4d0-5e6a-4322-9ff2-d521cda51a2d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Deep soft tissue', 'Perineurioma', 'Low-grade fibromyxoid sarcoma', 'Immunohistochemistry', 'Swirling growth', 'Deep soft tissue', 'Perineurioma', 'Low-grade fibromyxoid sarcoma', 'Immunohistochemistry', 'Swirling growth']",
"noisy_text": " involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is more of a difficult problem because perineurioma has a lot of overlap histologically with low-grade fibromyxoid sarcoma and also immunohistochemically. On immunostains, EMA, Clodin-1 and Glut-1 are three immunostains that will usually stain perineuriomas. The problem is that low-grade fibromyxoid sarcomas often express at least focal EMA, so that's a problem and additionally, the examples of low-grade fibromyxoid sarcoma that have dramatic swirling and whirling growth, those are the ones that have a perineurioma like pattern, the ones that mimic perineurioma. They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The",
"corrected_text": " involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is more of a difficult problem because perineurioma has a lot of overlap histologically with low-grade fibromyxoid sarcoma and also immunohistochemically. On immunostains, EMA, Clodin-1 and Glut-1 are three immunostains that will usually stain perineuriomas. The problem is that low-grade fibromyxoid sarcomas often express at least focal EMA, so that's a problem and additionally, the examples of low-grade fibromyxoid sarcoma that have dramatic swirling and whirling growth, those are the ones that have a perineurioma like pattern, the ones that mimic perineurioma. They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The",
"med_umls_ids": "[[{'entity': 'CD34', 'concept_id': 'C0054953', 'confidence': 1.0}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'deep soft tissue tumors', 'concept_id': 'C0037579', 'confidence': 0.8622524738311768}], [{'entity': 'Perineurioma', 'concept_id': 'C0751691', 'confidence': 0.9999999403953552}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'histologically', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'immunohistochemistry', 'concept_id': 'C0021044', 'confidence': 0.9999998807907104}], [{'entity': 'EMA', 'concept_id': 'C0268596', 'confidence': 0.9999999403953552}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}, {'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'immunohistochemical stains', 'concept_id': 'C4317108', 'confidence': 0.9999999403953552}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibrosarcomas', 'concept_id': 'C0016057', 'confidence': 1.0}, {'entity': 'EMA', 'concept_id': 'C0268596', 'confidence': 0.9999999403953552}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}], [{'entity': 'Low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'swirling', 'concept_id': 'C0233591', 'confidence': 0.7064549922943115}, {'entity': 'growth', 'concept_id': 'C0018270', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'express', 'concept_id': 'C0017262', 'confidence': 0.8176293969154358}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}], [{'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'reports', 'concept_id': 'C0684224', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcomas', 'concept_id': 'C1275282', 'confidence': 0.8123146891593933}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_453",
"caption_rating": "8"
},
{
"": "1008383",
"caption": "Secondary tumors can colonize the surface and mimic a primary lesion.",
"image_path": "iklRyY1nBIE_image_d8f95d8f-96e0-4889-9a62-34c9265898a1.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['Invasive urethral carcinoma involving the prostate.', 'Possible origin of the carcinoma from the prosthetic urethra or bladder.']",
"noisy_text": " So this is an invasive component. So it's very important to document that. So you can't just say urethral carcinoma involving the prostate, you need to say there's a lot of colonization. But you need to also make it clear that there's an invasive component. Now the next question some of you may ask me is, OK, so where is this coming from? Is this coming from the prosthetic urethra? Is this coming from the bladder? And sometimes you can't tell. And it's very important, to be honest, in your report, especially if it's a small biopsy or a top sample, where you can't see urethral carcinoma inside the component, that it could be arising from the prosthetic urethra. But you cannot exclude the possibility of this arising from the bladder. It's very important to document that. Even if you see an incisor component, that does not exclude that it's coming from the bladder. Because sometimes you can have secondary tumors colonize the surface and mimic a primary lesion. So that's an important point to keep in mind. So that was an interesting case I thought I'd share. We're going to move on to case nine shortly. Case nine is a 45-year-old gentleman that presented with a positive digital rectal examination and elevated PSA levels. So remember that age is just 45. I also shared this with you. I think",
"corrected_text": " So this is an invasive component. So it's very important to document that. So you can't just say urethral carcinoma involving the prostate, you need to say there's a lot of colonization. But you need to also make it clear that there's an invasive component. Now the next question some of you may ask me is, OK, so where is this coming from? Is this coming from the prosthetic urethra? Is this coming from the bladder? And sometimes you can't tell. And it's very important, to be honest, in your report, especially if it's a small biopsy or a top sample, where you can't see urethral carcinoma inside the component, that it could be arising from the prosthetic urethra. But you cannot exclude the possibility of this arising from the bladder. It's very important to document that. Even if you see an incisor component, that does not exclude that it's coming from the bladder. Because sometimes you can have secondary tumors colonize the surface and mimic a primary lesion. So that's an important point to keep in mind. So that was an interesting case I thought I'd share. We're going to move on to case nine shortly. Case nine is a 45-year-old gentleman that presented with a positive digital rectal examination and elevated PSA levels. So remember that age is just 45. I also shared this with you. I think",
"med_umls_ids": "[[{'entity': 'Invasive', 'concept_id': 'C0205281', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'colonization', 'concept_id': 'C4289767', 'confidence': 1.0}], [{'entity': 'document', 'concept_id': 'C1301746', 'confidence': 1.0}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}, {'entity': 'component', 'concept_id': 'C0449432', 'confidence': 1.0}, {'entity': 'origin', 'concept_id': 'C0079946', 'confidence': 1.0}, {'entity': 'carcinoma', 'concept_id': 'C0007097', 'confidence': 1.0}], [{'entity': 'Secondary tumors', 'concept_id': 'C0027627', 'confidence': 0.9999999403953552}, {'entity': 'colonize', 'concept_id': 'C3829074', 'confidence': 0.6422675251960754}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'primary', 'concept_id': 'C0205225', 'confidence': 1.0}, {'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_454",
"caption_rating": "8"
},
{
"": "1005560",
"caption": "The presence of a ring chromosome and translocation involving collagen A and platelet-derived growth factor is classic for DFSP.",
"image_path": "LlPaENuqzVQ_image_98c4a67e-3d00-4305-a909-bf584c2ec7a5.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['diffuse pattern between and among lipocytes', 'diffuse pattern between and among lipocytes', 'typical storiform pattern', 'ring chromosome', 'translocation involving collagen A and platelet-derived growth factor']",
"noisy_text": " you can impress your friends and colleagues. You can say, this is DFSB. You don't need the storiform pattern. If you see this, you got the diagnosis. No other neoplasm really gets diffusely between and among lipocytes in a diffuse pattern like this, other than DFSB. Now you look up here and yeah, you do have the nice, beautiful storiform pattern here. And you don't really need a CD34 stain here. You can do it if you want to, if you like to sort of charge patients extra money, but this is a classic DFSB. And that ring chromosome, the collagen A, platelet-derived growth factor, the translocation is classic for that. And one",
"corrected_text": " you can impress your friends and colleagues. You can say, this is DFSP. You don't need the storiform pattern. If you see this, you got the diagnosis. No other neoplasm really gets diffusely between and among lipocytes in a diffuse pattern like this, other than DFSP. Now you look up here and yeah, you do have the nice, typical storiform pattern here. And you don't really need a CD34 stain here. You can do it if you want to, if you like to sort of charge patients extra money, but this is a classic DFSP. And that ring chromosome, the collagen A, platelet-derived growth factor, the translocation is classic for that. And one",
"med_umls_ids": "[[{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'diffuse', 'concept_id': 'C0205219', 'confidence': 1.0}, {'entity': 'lipocytes', 'concept_id': 'C0206131', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}], [{'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}, {'entity': 'storiform pattern', 'concept_id': 'C1336510', 'confidence': 0.8142904043197632}], [{'entity': 'CD34 stain', 'concept_id': 'C0038128', 'confidence': 0.5134490728378296}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'ring chromosome', 'concept_id': 'C0035639', 'confidence': 1.0}, {'entity': 'translocation', 'concept_id': 'C0040715', 'confidence': 1.0}, {'entity': 'collagen A', 'concept_id': 'C0009325', 'confidence': 0.9128584265708923}, {'entity': 'platelet-derived growth factor', 'concept_id': 'C0032200', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_455",
"caption_rating": "9"
},
{
"": "1006715",
"caption": "Contains at least two distinct clonal populations of melanocytes with different morphology.",
"image_path": "8S4LeiO6Bbk_image_fa75fb91-7aa6-4884-bc95-cc3b6603e230.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Dendritic and spindle-shaped melanocytes', 'Heavily pigmented melanophages', 'Sclerotic stroma', 'Combined melanocytic nevus with features of common/benign nevus and blue nevus', 'Dendritic and spindle-shaped melanocytes', 'Heavily pigmented melanophages', 'Sclerotic stroma', 'Combined melanocytic nevus with features of common/benign nevus and blue nevus']",
"noisy_text": " or fusiform-shaped nuclei. They're arranged in short, intersecting vascals. And in between the dendritic and spindled melanocytes, we have very heavily pigmented melanovagias, all set in a sclerotic stroma. So basically, we have here a combined melanocytic nevus, one that has features of both a common or banal nevus and a blue nevus. And this is amongst the most common type of combined melanocytic nevus. By definition, a combined melanocytic nevus has at least two, sometimes more, distinct clonal populations of melanocytes that have a different morphology. And sometimes this is referred to as a true blue nevus because it's a true nevus or a banal nevus and a blue nevus. But it's possible to have all kinds of combinations. We can get a blue nevus with a spitz nevus. We can get balloon cell nevi. Those are combined nevi because you usually have a population of banal appearing melanocytes and balloon melanocytes. At that point, inactivated melanocytic tumors are frequently combined nevi, commonly characterized by banal nevus and a population of very epithelial spits like melanocytes. So anyway, all possible combinations are... And in actuality, a deep penetrating nevus is frequently combined nevus with a combination of banal nevus and what looks oftentimes like a cellular blue nevus. So anyway, this is a combined melanocytic nevus.",
"corrected_text": " or fusiform-shaped nuclei. They're arranged in short, intersecting vessels. And in between the dendritic and spindled melanocytes, we have very heavily pigmented melanophages, all set in a sclerotic stroma. So basically, we have here a combined melanocytic nevus, one that has features of both a common or banal nevus and a blue nevus. And this is amongst the most common type of combined melanocytic nevus. By definition, a combined melanocytic nevus has at least two, sometimes more, distinct clonal populations of melanocytes that have a different morphology. And sometimes this is referred to as a true blue nevus because it's a true nevus or a banal nevus and a blue nevus. But it's possible to have all kinds of combinations. We can get a blue nevus with a spitz nevus. We can get balloon cell nevi. Those are combined nevi because you usually have a population of banal appearing melanocytes and balloon melanocytes. At that point, inactivated melanocytic tumors are frequently combined nevi, commonly characterized by banal nevus and a population of very epithelial spits like melanocytes. So anyway, all possible combinations are... And in actuality, a deep penetrating nevus is frequently combined nevus with a combination of banal nevus and what looks oftentimes like a cellular blue nevus. So anyway, this is a combined melanocytic nevus.",
"med_umls_ids": "[[{'entity': 'Combined', 'concept_id': 'C0205195', 'confidence': 1.0}, {'entity': 'melanocytic nevus', 'concept_id': 'C0027962', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'benign nevus', 'concept_id': 'C1456781', 'confidence': 1.0}, {'entity': 'blue nevus', 'concept_id': 'C0206736', 'confidence': 1.0}], [{'entity': 'Contains', 'concept_id': 'C0332256', 'confidence': 0.9999999403953552}, {'entity': 'clonal populations', 'concept_id': 'C0032659', 'confidence': 0.8110582232475281}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}], [{'entity': 'combinations', 'concept_id': 'C0453882', 'confidence': 1.0}, {'entity': 'combined', 'concept_id': 'C0205195', 'confidence': 1.0}, {'entity': 'nevi', 'concept_id': 'C0027960', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_456",
"caption_rating": "9"
},
{
"": "1005117",
"caption": "Neoplastic process is present in the tissue fragments.",
"image_path": "8S4LeiO6Bbk_image_16dcef57-bfaa-4dd7-9077-d079e0cacb50.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['neoplastic process', 'blue tumor', 'nuclei', 'epithelial tumor', 'cribriform pattern']",
"noisy_text": " again, a very, very nice biopsy. Moving on to slide number three, we're changing directions here. Here we have several fragments of tissue and in looking at this, this is pretty clear that we're dealing with a neoplastic process. It's somewhat fragmented, but seems to be fairly well circumscribed. At scan, one can see that we've got a blue tumor or blue ball present here, and the blue staining is generally due to hematoxylin staining the nucleus. So we've got a lot of nuclei here that we'll want to take a look at. Overall, even though this is fragmented, the fact that it's fairly well circumscribed would indicate that it's got more of a benign silhouette. If we move to higher power, we can see that we're dealing with an epithelial rather than a mosaicable tumor. We've got interconnected cords and strands. We have somewhat of a ribiform pattern here, and",
"corrected_text": " again, a very, very nice biopsy. Moving on to slide number three, we're changing directions here. Here we have several fragments of tissue and in looking at this, this is pretty clear that we're dealing with a neoplastic process. It's somewhat fragmented, but seems to be fairly well circumscribed. At scan, one can see that we've got a blue tumor or blue ball present here, and the blue staining is generally due to hematoxylin staining the nucleus. So we've got a lot of nuclei here that we'll want to take a look at. Overall, even though this is fragmented, the fact that it's fairly well circumscribed would indicate that it's got more of a benign silhouette. If we move to higher power, we can see that we're dealing with an epithelial rather than a mesenchymal tumor. We've got interconnected cords and strands. We have somewhat of a cribriform pattern here, and",
"med_umls_ids": "[[{'entity': 'Neoplastic process', 'concept_id': 'C0027671', 'confidence': 1.0}, {'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'fragments', 'concept_id': 'C0332255', 'confidence': 1.0}], [{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'well-circumscribed', 'concept_id': 'C1707398', 'confidence': 0.9430561065673828}, {'entity': 'blue staining', 'concept_id': 'C0025746', 'confidence': 0.7925992608070374}, {'entity': 'hematoxylin staining', 'concept_id': 'C0018964', 'confidence': 0.9091285467147827}, {'entity': 'nucleus', 'concept_id': 'C0007610', 'confidence': 1.0}], [{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'epithelial', 'concept_id': 'C0221908', 'confidence': 1.0}, {'entity': 'mesenchymal origin', 'concept_id': 'C1513143', 'confidence': 0.8364232778549194}], [{'entity': 'Interconnected', 'concept_id': 'C0683595', 'confidence': 0.8500909209251404}, {'entity': 'cords', 'concept_id': 'C0034869', 'confidence': 0.801885187625885}, {'entity': 'strands', 'concept_id': 'C0600383', 'confidence': 0.800572395324707}, {'entity': 'cribriform pattern', 'concept_id': 'C1333163', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_457",
"caption_rating": "8"
},
{
"": "1005912",
"caption": "Description of pancreatic acinar metaplasia in the stomach and small intestine.",
"image_path": "r7OA0Trj5hQ_image_4157ef08-acc5-47ab-9bf5-08ff4ba36653.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['pancreatic acinar-like structures in the GIT', 'acinar structures resembling pancreas', 'pancreatic acinar-like structures in the GIT']",
"noisy_text": " Sometimes the stomach can show acinar structures resembling pancreas. Then it is known as pancreatic acinar metaplasia. This can also happen in the small intestine. There, when you do staining for amylase or trypsin, it will be positive, but on H&E itself, you can see pancreatic acinar-like structures in the GIT. Then it will become pancreatic acinar metaplasia. Here is the best example of atrophy. Again, unfortunately, there is no defined number of glands to be seen because this is age-dependentation, size-dependentation, race-dependent. So",
"corrected_text": " Sometimes the stomach can show acinar structures resembling pancreas. Then it is known as pancreatic acinar metaplasia. This can also happen in the small intestine. There, when you do staining for amylase or trypsin, it will be positive, but on H&E itself, you can see pancreatic acinar-like structures in the GIT. Then it will become pancreatic acinar metaplasia. Here is the best example of atrophy. Again, unfortunately, there is no defined number of glands to be seen because this is age-dependentation, size-dependentation, race-dependent. So",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'pancreatic acinar metaplasia', 'concept_id': 'C4021967', 'confidence': 0.7844848036766052}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'small intestine', 'concept_id': 'C0021852', 'confidence': 1.0}], [{'entity': 'Staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'amylase', 'concept_id': 'C0002712', 'confidence': 1.0}, {'entity': 'trypsin', 'concept_id': 'C0041236', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'intestine', 'concept_id': 'C0021853', 'confidence': 1.0}], [{'entity': 'atrophy', 'concept_id': 'C0333641', 'confidence': 1.0}, {'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'age', 'concept_id': 'C0001779', 'confidence': 1.0}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'dependence', 'concept_id': 'C0011546', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_458",
"caption_rating": "8"
},
{
"": "1005194",
"caption": "Identification of a classic DFSP with a storiform pattern and a ring chromosome, collagen A, platelet-derived growth factor, and translocation.",
"image_path": "LlPaENuqzVQ_image_cc6b78f5-e9e0-4a20-bb93-d4a40aa06b50.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['Storiform pattern', 'Ring chromosome', 'Collagen A', 'Platelet-derived growth factor', 'Soft tissue neoplasm', 'Storiform pattern', 'Ring chromosome', 'Collagen A', 'Platelet-derived growth factor', 'Soft tissue neoplasm']",
"noisy_text": " you do have the nice, beautiful storiform pattern here. And you don't really need a CD34 stain here. You can do it if you want to, if you like to sort of charge patients extra money, but this is a classic DFSB. And that ring chromosome, the collagen A, platelet-derived growth factor, the translocation is classic for that. And one other thing, if you biopsy the surface of DFSB, sometimes it can look like a neurofibroma. So beware of taking superficial shave biopsies of DFSBs. You need to take a deep incisional biopsy. Whenever you're dealing with a soft tissue neoplasm and dermatology, get out the knife and fork. Don't get the punch biopsy out. Don't ever do a shave on it. So you got to take a real biopsy when you're dealing with a soft tissue neoplasm because of",
"corrected_text": " you do have the nice, beautiful storiform pattern here. And you don't really need a CD34 stain here. You can do it if you want to, if you like to sort of charge patients extra money, but this is a classic DFSP. And that ring chromosome, the collagen A, platelet-derived growth factor, the translocation is classic for that. And one other thing, if you biopsy the surface of DFSP, sometimes it can look like a neurofibroma. So beware of taking superficial shave biopsies of DFSBs. You need to take a deep incisional biopsy. Whenever you're dealing with a soft tissue neoplasm and dermatology, get out the knife and fork. Don't get the punch biopsy out. Don't ever do a shave on it. So you got to take a real biopsy when you're dealing with a soft tissue neoplasm because of",
"med_umls_ids": "[[{'entity': 'Identification', 'concept_id': 'C0020792', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}, {'entity': 'storiform pattern', 'concept_id': 'C1336510', 'confidence': 0.8142904043197632}, {'entity': 'ring chromosome', 'concept_id': 'C0035639', 'confidence': 1.0}, {'entity': 'collagen A', 'concept_id': 'C0009325', 'confidence': 0.9128584265708923}, {'entity': 'platelet-derived growth factor', 'concept_id': 'C0032200', 'confidence': 1.0}, {'entity': 'translocation', 'concept_id': 'C0040715', 'confidence': 1.0}], [{'entity': 'Caution', 'concept_id': 'C1882442', 'confidence': 0.7039048671722412}, {'entity': 'superficial', 'concept_id': 'C0205124', 'confidence': 1.0}, {'entity': 'DFSPs', 'concept_id': 'C0334464', 'confidence': 0.8083938360214233}, {'entity': 'recommendation', 'concept_id': 'C0034866', 'confidence': 1.0}, {'entity': 'deep incisional biopsy', 'concept_id': 'C0184922', 'confidence': 0.8345454335212708}, {'entity': 'dealing', 'concept_id': 'C0556449', 'confidence': 0.7019717693328857}, {'entity': 'soft tissue neoplasm', 'concept_id': 'C0037579', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_459",
"caption_rating": "8"
},
{
"": "1008853",
"caption": "This is not porokeratosis, as there are no granulomatous abnormalities or dyskeratotic keratinocytes.",
"image_path": "udoW6VSqsm4_image_8a7aef14-e5a9-4b2a-aff2-2e10682e9d63.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['loss of cornified layer', 'acral area', 'clonal abnormality of the epithelium', 'no granulomatous abnormalities', 'dyskeratotic keratinocytes']",
"noisy_text": " It's a small little area, it's almost kind of the negatives of poro, where you get a corneal lamella. Well, this is where you get no corneal lamella. You just get loss of the coronified layer, essentially. It's probably some type of little clonal abnormality of the epithelium. And they just don't make the same amount of stratum corneum that they normally should. It's usually focally like this. It's acral, so it's localized, and that's why it's called acral condition. So, this is a beautiful example of that. And so, the other things we kind of talked about are a bit differential, but next slide. Nothing else really will give you this kind of localized circumscribed area like this, so it's not poro. That would have a coronal lamella with granulocidal abnormalities and dyskeratonic keratinocytes. We don't see that here, so this is just a loss of the coronified layer. And there's one other condition where you kind of get, where are some other little clonal, you know, somatic mutations that you can get abnormalities in the epithelium that occur just in localized areas. That's not",
"corrected_text": " It's a small little area, it's almost kind of the negatives of poro, where you get a cornified layer. Well, this is where you get no cornified layer. You just get loss of the cornified layer, essentially. It's probably some type of little clonal abnormality of the epithelium. And they just don't make the same amount of stratum corneum that they normally should. It's usually focally like this. It's acral, so it's localized, and that's why it's acrokeratosis. So, this is a beautiful example of that. And so, the other things we kind of talked about are a bit differential, but next slide. Nothing else really will give you this kind of localized circumscribed area like this, so it's not poro. That would have a cornified layer with granulomatous abnormalities and dyskeratotic keratinocytes. We don't see that here, so this is just a loss of the cornified layer. And there's one other condition where you kind of get, where are some other little clonal, you know, somatic mutations that you can get abnormalities in the epithelium that occur just in localized areas. That's not",
"med_umls_ids": "[[{'entity': 'Loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'localized', 'concept_id': 'C0392752', 'confidence': 1.0}, {'entity': 'acral area', 'concept_id': 'C0439746', 'confidence': 0.7208066582679749}, {'entity': 'clonal abnormality', 'concept_id': 'C1704258', 'confidence': 0.8401584029197693}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}], [{'entity': 'porokeratosis', 'concept_id': 'C0162839', 'confidence': 1.0}, {'entity': 'granulomatous abnormalities', 'concept_id': 'C0439667', 'confidence': 0.7099277377128601}, {'entity': 'dyskeratotic keratinocytes', 'concept_id': 'C1512099', 'confidence': 0.9701507091522217}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_460",
"caption_rating": "8"
},
{
"": "1006347",
"caption": "The key differential diagnosis is an acquired digital fibroma or an acquired digital fibrokeratoma.",
"image_path": "8S4LeiO6Bbk_image_89afc7b2-8d75-4b3c-9eff-ab85550d9c16.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['nerve fascicles', 'spindle-shaped cells', 'rudimentary supernumerary digit', 'ulnar aspect of the fifth digit', 'acquired digital fibroma', 'acquired digital fibrokeratoma', 'trichilemmal cyst', 'nerve fascicles', 'spindle-shaped cells', 'rudimentary supernumerary digit', 'ulnar aspect of the fifth digit', 'acquired digital fibroma', 'acquired digital fibrokeratoma', 'trichilemmal cyst']",
"noisy_text": " core here we've got several well-defined nerve fascicles and the spindled cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions of course tend to occur along the ulnar eye aspect of the fifth digit. They're not infrequently bilateral and the key differential here of course is an acquired digital fibroma or an acquired digital fibrocarotoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if",
"corrected_text": " core here we've got several well-defined nerve fascicles and the spindle cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions of course tend to occur along the ulnar eye aspect of the fifth digit. They're not infrequently bilateral and the key differential here of course is an acquired digital fibroma or an acquired digital fibrokeratoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if",
"med_umls_ids": "[[{'entity': 'Well-defined nerve fascicles', 'concept_id': 'C1185741', 'confidence': 0.5682494640350342}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'S100', 'concept_id': 'C3273837', 'confidence': 1.0}, {'entity': 'SOX10', 'concept_id': 'C1420317', 'confidence': 0.9999998807907104}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'rudimentary supernumerary digit', 'concept_id': 'C0152427', 'confidence': 0.8142021894454956}], [{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'ulnar', 'concept_id': 'C0442044', 'confidence': 1.0}, {'entity': 'aspect', 'concept_id': 'C1547011', 'confidence': 1.0}, {'entity': 'fifth digit', 'concept_id': 'C0230403', 'confidence': 0.912693440914154}, {'entity': 'bilateral', 'concept_id': 'C0238767', 'confidence': 1.0}], [{'entity': 'differential diagnosis', 'concept_id': 'C0011906', 'confidence': 1.0}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}, {'entity': 'digital fibroma', 'concept_id': 'C4538745', 'confidence': 0.8997364640235901}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}], [{'entity': 'Trichilemmal cyst', 'concept_id': 'C2266788', 'confidence': 1.0}, {'entity': 'biopsy specimen', 'concept_id': 'C0677862', 'confidence': 1.0}, {'entity': 'slide number', 'concept_id': 'C3828004', 'confidence': 0.8261933326721191}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_461",
"caption_rating": "8"
},
{
"": "1007414",
"caption": "Neutrophils present in acanthotic skin and parakeratotic layer.",
"image_path": "yGCjnNbC7Qs_image_e1e744d0-1856-4a65-822b-b9881906642d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['increased glycogen', 'neutrophils', 'acanthotic skin', 'parakeratosis', 'parakeratotic layer', 'neutrophils']",
"noisy_text": " there is sponge users as well as increased glycogen within these cells which contributes to the clear cell or pale look. And the increased glycogen we can appreciate them if we do a PA stain. Again this we can see the neutrophils are here. So there will be neutrophils in the akathotic skin. Then what is there? This is the parakeratosis. And this is not just parakeratosis. We can see that there is neutrophils in this parakeratotic layer. So there is parakeratosis with neutrophils. There is acanthosis with",
"corrected_text": " there is sponge users as well as increased glycogen within these cells which contributes to the clear cell or pale look. And the increased glycogen we can appreciate them if we do a PA stain. Again this we can see the neutrophils are here. So there will be neutrophils in the acanthotic skin. Then what is there? This is the parakeratosis. And this is not just parakeratosis. We can see that there is neutrophils in this parakeratotic layer. So there is parakeratosis with neutrophils. There is acanthosis with",
"med_umls_ids": "[[{'entity': 'Increased', 'concept_id': 'C0205217', 'confidence': 1.0}, {'entity': 'glycogen', 'concept_id': 'C0017911', 'confidence': 1.0}, {'entity': 'sponge users', 'concept_id': 'C1706077', 'confidence': 0.7141918540000916}, {'entity': 'cell', 'concept_id': 'C0007634', 'confidence': 1.0}, {'entity': 'pale', 'concept_id': 'C0030232', 'confidence': 1.0}], [{'entity': 'Neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'acanthotic skin', 'concept_id': 'C0333991', 'confidence': 0.8280558586120605}, {'entity': 'parakeratotic layer', 'concept_id': 'C0334064', 'confidence': 0.8241937756538391}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_462",
"caption_rating": "8"
},
{
"": "1005517",
"caption": "Degeneration of collagen and elastic fibers, with eosinophilic proteins precipitating on the collagen bundles. Clinical presentation of edematous, fixed lesions that can resemble drug reactions.",
"image_path": "udoW6VSqsm4_image_573ffb23-f4ba-4f8c-ab2c-dbcae2f38110.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['Collagen and elastic fibers', 'Eosinophilic proteins precipitating on collagen bundles', 'Clinical photo of edematous lesions', 'Drug reactions that resemble the lesions', 'Tylenol-related lesions called Wells.', 'Collagen and elastic fibers', 'Eosinophilic proteins precipitating on collagen bundles', 'Clinical photo of edematous lesions', 'Drug reactions that resemble the lesions', 'Tylenol-related lesions called Wells.']",
"noisy_text": " Collagen, elastic fibers, and they kind of get degenerated, and then those eosinophilic proteins kind of precipitate on the collagen bundles. Normally, eosinophils are thought to be useful for degrading on parasites if you turn it into plane figures. This is just a situation where it's like attacking the normal collagen bundles and elastic fibers. Let's take a look at a clinical photo. Here you see it. They're basically just these edematous, usually relatively fixed lesions. Welles like drug reactions, too, that can look like this sometimes. We saw that a few years ago. They're related to Tylenol, so that's something we can see that on the page. Welles, that's what this was. It's a",
"corrected_text": " Collagen, elastic fibers, and they kind of get degenerated, and then those eosinophilic proteins kind of precipitate on the collagen bundles. Normally, eosinophils are thought to be useful for degrading on parasites if you turn it into plane figures. This is just a situation where it's like attacking the normal collagen bundles and elastic fibers. Let's take a look at a clinical photo. Here you see it. They're basically just these edematous, usually relatively fixed lesions. Welles like drug reactions, too, that can look like this sometimes. We saw that a few years ago. They're related to Tylenol, so that's something we can see that on the page. Welles, that's what this was. It's a",
"med_umls_ids": "[[{'entity': 'Degeneration', 'concept_id': 'C0011164', 'confidence': 1.0}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'elastic fibers', 'concept_id': 'C0230899', 'confidence': 0.9999999403953552}, {'entity': 'eosinophilic proteins', 'concept_id': 'C0333930', 'confidence': 0.8475342392921448}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'bundles', 'concept_id': 'C3658308', 'confidence': 0.8706014752388}, {'entity': 'Clinical presentation', 'concept_id': 'C4554564', 'confidence': 0.8858868479728699}, {'entity': 'edematous', 'concept_id': 'C0013604', 'confidence': 1.0}, {'entity': 'fixed lesions', 'concept_id': 'C0443218', 'confidence': 0.764360249042511}, {'entity': 'drug reactions', 'concept_id': 'C0041755', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_463",
"caption_rating": "8"
},
{
"": "1009202",
"caption": "Lymphocytes are hyperchromatic and can be used as a reference for comparison.",
"image_path": "Wiyo6taYRF4_image_3be5b638-4395-4420-999d-4f2722044361.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Hematopathology', 'Neuropathology', 'Cytopathology']",
"roi_text": "['Vesicular nuclei', 'Lymphocytes', 'Vesicular nuclei', 'Lymphocytes']",
"noisy_text": " very actively proliferating. So let's see one example of vesicular nuclei here. So these are the nuclei. So if you see here, the nucleus has got a very finely lightly strained chromatin and a prominent big eosinophilic nuclei. So normally, whenever we see a vesicular nuclei, they're generally accompanied by a prominent big eosinophilic nuclei. So whenever we are describing a vesicular nuclei, that is, we are saying that the nucleus is lightly strained, we are also saying that the cell is also having a prominent nuclei. And if you compare these cells with few of the lymphocytes here, so lymphocytes are the best cell in reference. And you can always compare the nucleus which you are typing with the lymphocytes in vicinity. And lymphocytes are usually hyperchromatic, that is, they're darkly strained. So as compared to this cell, you see that the nucleus is",
"corrected_text": " very actively proliferating. So let's see one example of vesicular nuclei here. So these are the nuclei. So if you see here, the nucleus has got a very finely lightly strained chromatin and a prominent big eosinophilic nuclei. So normally, whenever we see a vesicular nuclei, they're generally accompanied by a prominent big eosinophilic nuclei. So whenever we are describing a vesicular nuclei, that is, we are saying that the nucleus is lightly strained, we are also saying that the cell is also having a prominent nuclei. And if you compare these cells with few of the lymphocytes here, so lymphocytes are the best cell in reference. And you can always compare the nucleus which you are typing with the lymphocytes in vicinity. And lymphocytes are usually hyperchromatic, that is, they're darkly strained. So as compared to this cell, you see that the nucleus is",
"med_umls_ids": "[[{'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'proliferating', 'concept_id': 'C1514485', 'confidence': 1.0}], [{'entity': 'Vesicular nuclei', 'concept_id': 'C2325471', 'confidence': 0.7651268839836121}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'chromatin', 'concept_id': 'C0008546', 'confidence': 1.0}, {'entity': 'eosinophilic nucleus', 'concept_id': 'C0333930', 'confidence': 0.7939648628234863}], [{'entity': 'Lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'hyperchromatic', 'concept_id': 'C0333911', 'confidence': 1.0}, {'entity': 'comparison', 'concept_id': 'C1707455', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1152.0",
"id": "test_464",
"caption_rating": "8"
},
{
"": "1007318",
"caption": "Biopsies from patients with chlamydia and syphilis may show granulation tissue.",
"image_path": "sDFjOtMAYrk_image_f6beef0e-7034-420f-94bb-c988b8bcb03a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['Biopsy from the rectum.']",
"noisy_text": " And this is a patient with chlamydia. I'm sorry, the slide is a little bit faded. I don't know why because it's from 2015, but this is just goes to show you how the pattern of inflammation and distortion is really, can be different from case to case. So in this one did not have as much in the way of lamina propria expansion, but it had some architectural distortion here and there, maybe a little bit too cellular for a biopsy from the rectum and maybe a couple of lymphoid aggregates, but very little in the way of active inflammation and maybe, you know, a little bit of granulation tissue. And speaking of granulation tissue, on rare occasions, you'll get biopsies from patients with chlamydia and even syphilis. And all",
"corrected_text": " And this is a patient with chlamydia. I'm sorry, the slide is a little bit faded. I don't know why because it's from 2015, but this is just goes to show you how the pattern of inflammation and distortion is really, can be different from case to case. So in this one did not have as much in the way of lamina propria expansion, but it had some architectural distortion here and there, maybe a little bit too cellular for a biopsy from the rectum and maybe a couple of lymphoid aggregates, but very little in the way of active inflammation and maybe, you know, a little bit of granulation tissue. And speaking of granulation tissue, on rare occasions, you'll get biopsies from patients with chlamydia and even syphilis. And all",
"med_umls_ids": "[[{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'chlamydia', 'concept_id': 'C0008148', 'confidence': 1.0}], [{'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}, {'entity': 'inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}, {'entity': 'distortion', 'concept_id': 'C0332482', 'confidence': 1.0}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}], [{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'rectum', 'concept_id': 'C0034896', 'confidence': 1.0}, {'entity': 'architectural distortion', 'concept_id': 'C2826609', 'confidence': 1.0}, {'entity': 'granulation', 'concept_id': 'C0518864', 'confidence': 1.0}], [{'entity': 'Biopsies', 'concept_id': 'C0005558', 'confidence': 1.0}, {'entity': 'patients', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'chlamydia', 'concept_id': 'C0008148', 'confidence': 1.0}, {'entity': 'syphilis', 'concept_id': 'C0039128', 'confidence': 1.0}, {'entity': 'granulation tissue', 'concept_id': 'C0018180', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_465",
"caption_rating": "7"
},
{
"": "1008577",
"caption": "Description of nuclear placement in xanthoma and signet ring cells. Diagnosis of gastric xanthoma and poorly differentiated signet cell carcinoma.",
"image_path": "r7OA0Trj5hQ_image_bf291346-c4e7-4ac7-8f76-e87f659e4d0a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['centrally placed nucleus', 'peripherally pushed nucleus', 'gastric xanthoma', 'signet ring cells', 'poorly differentiated signet cell carcinoma']",
"noisy_text": " most of the time centrally placed nucleus. Sometimes it is pushed to the periphery. The central nuclear placement is very important for a diagnosis of xanthoma. For a signet cells, it will be predominantly peripherally pushed nucleus. And when you have doubt, you do a CD68, which will be strongly positive. And so this is a gastric xanthoma. Here, it is more like a signet cells. And when you do cytokeratin, it will all be positive. So it's a poorly differentiated signet cell carcinoma. And there are only three types of pathologists in the world. And this, I got it again from Twitter, I think from",
"corrected_text": " most of the time centrally placed nucleus. Sometimes it is pushed to the periphery. The central nuclear placement is very important for a diagnosis of xanthoma. For a signet cells, it will be predominantly peripherally pushed nucleus. And when you have doubt, you do a CD68, which will be strongly positive. And so this is a gastric xanthoma. Here, it is more like a signet cells. And when you do cytokeratin, it will all be positive. So it's a poorly differentiated signet cell carcinoma. And there are only three types of pathologists in the world. And this, I got it again from Twitter, I think from",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'nuclear', 'concept_id': 'C0521447', 'confidence': 1.0}, {'entity': 'xanthoma', 'concept_id': 'C0302314', 'confidence': 1.0}, {'entity': 'signet ring cells', 'concept_id': 'C0333727', 'confidence': 1.0}, {'entity': 'Diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'gastric xanthoma', 'concept_id': 'C1282522', 'confidence': 1.0}, {'entity': 'poorly differentiated', 'concept_id': 'C0205617', 'confidence': 1.0}, {'entity': 'signet cell carcinoma', 'concept_id': 'C0206696', 'confidence': 0.9410539865493774}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_466",
"caption_rating": "8"
},
{
"": "1008341",
"caption": "Diagnosis of pigmented Bowen\u2019s disease or pigmented squamous cell carcinoma.",
"image_path": "8S4LeiO6Bbk_image_e9947037-d23a-421e-a41c-750914e5a706.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['abnormal maturation of keratinocytes', 'hyperchromatic cells', 'melanin pigment', 'dendritic melanocytes', 'abnormal maturation of keratinocytes', 'hyperchromatic cells', 'melanin pigment', 'dendritic melanocytes', 'abnormal maturation of keratinocytes', 'hyperchromatic cells', 'melanin pigment', 'dendritic melanocytes']",
"noisy_text": " I think would be reasonable considerations. However, if we move to higher power and begin to study the epidermis a little bit more carefully we can see that there's clear-cut abnormal maturation here. We've got full thickness keratinocytic atypia with nucleic acid or pleomorphic and hyperchromatic. There is abnormal maturation with even abnormal hyperchromatic perikaratotic cells within the stratum corneum. There's an increased amount of melanin pigment pressed within the basal layer and we can see that we've got an increased amount of melanin pigment and even a few dendritic melanocytes within the epidermis and so what we've got here is an example of pigmented Bowen's disease or pigmented squamous cell carcinoma. One could see similar changes in lesions",
"corrected_text": " I think would be reasonable considerations. However, if we move to higher power and begin to study the epidermis a little bit more carefully we can see that there's clear-cut abnormal maturation of keratinocytes here. We've got full thickness keratinocytic atypia with nucleic acid or pleomorphic and hyperchromatic. There is abnormal maturation with even abnormal hyperchromatic parakeratotic cells within the stratum corneum. There's an increased amount of melanin pigment pressed within the basal layer and we can see that we've got an increased amount of melanin pigment and even a few dendritic melanocytes within the epidermis and so what we've got here is an example of pigmented Bowen 's disease's disease or pigmented squamous cell carcinoma. One could see similar changes in lesions",
"med_umls_ids": "[[{'entity': 'Abnormal', 'concept_id': 'C0205161', 'confidence': 1.0}, {'entity': 'maturation', 'concept_id': 'C0678723', 'confidence': 1.0}, {'entity': 'keratinocytes', 'concept_id': 'C0022567', 'confidence': 1.0}, {'entity': 'thickness', 'concept_id': 'C1280412', 'confidence': 1.0}, {'entity': 'keratinocytic atypia', 'concept_id': 'C0741302', 'confidence': 0.6335055828094482}, {'entity': 'hyperchromatic cells', 'concept_id': 'C0333911', 'confidence': 0.823300302028656}, {'entity': 'stratum corneum', 'concept_id': 'C0221921', 'confidence': 1.0}], [{'entity': 'Increased', 'concept_id': 'C0205217', 'confidence': 1.0}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}, {'entity': 'pigment', 'concept_id': 'C0031911', 'confidence': 1.0}, {'entity': 'dendritic melanocytes', 'concept_id': 'C0025201', 'confidence': 0.7694142460823059}, {'entity': 'epidermis', 'concept_id': 'C0014520', 'confidence': 1.0}], [{'entity': 'Diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'Bowen\u2019s disease', 'concept_id': 'C0006079', 'confidence': 0.9730859994888306}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'squamous cell carcinoma', 'concept_id': 'C0007137', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_467",
"caption_rating": "8"
},
{
"": "1009167",
"caption": "No perineural invasion.",
"image_path": "LlPaENuqzVQ_image_3395cdb9-1f87-47eb-a619-494519571fd3.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['calcification']",
"noisy_text": " Here's another sclerosing epithelial neoplasm. And notice the stroma here. Can you tell the difference between this stroma and the one we just looked at in the MAC? See how fibrous this stroma is. These are more basophilic cells. There's calcification here. There may be some little small duct-like structures at the top of the calcification. This is a desmoplastic trichophthelioma. It's different than a MAC. So it's got a different morphology. It's got the calcification and different stroma. These do not get neurotropic involvement. So, and you know, this is a definitive diagnosis here also. We don't need to stain this or anything. We would",
"corrected_text": " Here's another sclerosing epithelial neoplasm. And notice the stroma here. Can you tell the difference between this stroma and the one we just looked at in the MAC? See how fibrous this stroma is. These are more basophilic cells. There's calcification here. There may be some little small duct-like structures at the top of the calcification. This is a desmoplastic trichoepithelioma. It's different than a MAC. So it's got a different morphology. It's got the calcification and different stroma. These do not get perineural invasion. So, and you know, this is a definitive diagnosis here also. We don't need to stain this or anything. We would",
"med_umls_ids": "[[{'entity': 'Sclerosing', 'concept_id': 'C0036426', 'confidence': 0.833010733127594}, {'entity': 'epithelial neoplasm', 'concept_id': 'C1368683', 'confidence': 1.0}, {'entity': 'fibrous stroma', 'concept_id': 'C1180207', 'confidence': 0.8035051226615906}, {'entity': 'calcification', 'concept_id': 'C0006660', 'confidence': 1.0}], [{'entity': 'Desmoplastic tricholemmomaphthelioma', 'concept_id': 'C1275206', 'confidence': 0.8335589170455933}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}, {'entity': 'stroma', 'concept_id': 'C0927195', 'confidence': 1.0}, {'entity': 'compared', 'concept_id': 'C1707455', 'confidence': 1.0}, {'entity': 'MAC', 'concept_id': 'C0009545', 'confidence': 0.9999999403953552}], [{'entity': 'perineural invasion', 'concept_id': 'C1317608', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_468",
"caption_rating": "8"
},
{
"": "1005288",
"caption": "Presence of crosstalk between stroma process and glands with basal cell hyperplasia in areas",
"image_path": "iklRyY1nBIE_image_018f29b1-c570-497d-9129-98642a46a135.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " That's something very important you want to exclude. But this is not melanoma. The patient did not have a history of melanoma. This does not look like prostate cancer, even though it can have sarcomatoid prostate cancer or prostatic adenocarcinoma with sarcomatoid features, which I'll share with you shortly. But there are a number of things that need to come into the differential. Something else you may have observed with this case is the fact that it's not just a stroma process. It looks like there's something else going on in the glands, too. And in the glands, it's almost like there's a crosstalk between the stroma process and the glands. The glands are benign, but they actually have what looks like basal cell hyperplasia in areas. And that's not uncommon with this entity. It is not unusual to have this entity, actually, with basal",
"corrected_text": " That's something very important you want to exclude. But this is not melanoma. The patient did not have a history of melanoma. This does not look like prostate cancer, even though it can have sarcomatoid prostate cancer or prostatic adenocarcinoma with sarcomatoid features, which I'share with you shortly. But there are a number of things that need to come into the differential. Something else you may have observed with this case is the fact that it's not just a stroma process. It looks like there's something else going on in the glands, too. And in the glands, it's almost like there's a crosstalk between the stroma process and the glands. The glands are benign, but they actually have what looks like basal cell hyperplasia in areas. And that's not uncommon with this entity. It is not unusual to have this entity, actually, with basal",
"med_umls_ids": "[[{'entity': 'Exclusion', 'concept_id': 'C0680251', 'confidence': 0.9999999403953552}, {'entity': 'melanoma', 'concept_id': 'C0025202', 'confidence': 1.0}, {'entity': 'prostate cancer', 'concept_id': 'C0376358', 'confidence': 1.0}, {'entity': 'sarcomatoid', 'concept_id': 'C0205697', 'confidence': 0.8252997994422913}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'differential diagnosis', 'concept_id': 'C0011906', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'crosstalk', 'concept_id': 'C0010357', 'confidence': 1.0}, {'entity': 'stroma', 'concept_id': 'C0927195', 'confidence': 1.0}, {'entity': 'process', 'concept_id': 'C1184743', 'confidence': 1.0}, {'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'basal cell hyperplasia', 'concept_id': 'C0333990', 'confidence': 1.0}], [{'entity': 'Benign', 'concept_id': 'C0205183', 'confidence': 1.0}, {'entity': 'nature', 'concept_id': 'C0349590', 'confidence': 1.0}, {'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'basal cell hyperplasia', 'concept_id': 'C0333990', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_469",
"caption_rating": "8"
},
{
"": "1009197",
"caption": "MUC4 stain is used to confirm the diagnosis of cellular intramuscular myxoma.",
"image_path": "QDb68_G1HR4_image_559a6539-9ae0-45d0-8273-a583aa8f043a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['myxoid features', 'fine delicate collagen', 'cellular intramuscular myxoma', 'fibrous areas', 'cellular areas', 'MUC4 stain']",
"noisy_text": " Here's again the myxoid background I really think this is very helpful. The very very fine delicate collagen that you see. Now areas like this I think can kind of resemble what you see in a so-called cellular intramuscular myxoma. Intramuscular myxomas are usually very blue and myxoid very hypocellular but sometimes they get more fibrous and more cellular areas. And on a needle biopsy I think that can be challenging. So I think usually with some experience you can tell them apart on H and E most of the time but when I have any doubt I just do a MUC4 stain. The MUC4 is negative and on a needle it looks like a myxoma with some kind of fibrous or a little bit more cellular areas and then I just say that it's probably a cellular intramuscular myxoma. So I think MUC4",
"corrected_text": " Here's again the myxoid background I really think this is very helpful. The very very fine delicate collagen that you see. Now areas like this I think can kind of resemble what you see in a so-called cellular intramuscular myxoma. Intramuscular myxomas are usually very blue and myxoid very hypocellular but sometimes they get more fibrous and more cellular areas. And on a needle biopsy I think that can be challenging. So I think usually with some experience you can tell them apart on H and E most of the time but when I have any doubt I just do a MUC4 stain. The MUC4 is negative and on a needle it looks like a myxoma with some kind of fibrous or a little bit more cellular areas and then I just say that it's probably a cellular intramuscular myxoma. So I think MUC4",
"med_umls_ids": "[[{'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'myxoid', 'concept_id': 'C0205295', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}], [{'entity': 'narrator', 'concept_id': 'C1135957', 'confidence': 0.7711340188980103}, {'entity': 'cellular', 'concept_id': 'C0007634', 'confidence': 0.9999999403953552}, {'entity': 'intramuscular', 'concept_id': 'C0442117', 'confidence': 1.0}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}, {'entity': 'cellular areas', 'concept_id': 'C0007634', 'confidence': 0.7882957458496094}], [{'entity': 'MUC4', 'concept_id': 'C1417496', 'confidence': 0.9999999403953552}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'confirm', 'concept_id': 'C0521093', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'cellular intramuscular myxoma', 'concept_id': 'C1334260', 'confidence': 0.8910117149353027}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_470",
"caption_rating": "9"
},
{
"": "1006849",
"caption": "The fibrovascular core contains well-defined nerve fascicles with spindle-shaped cells that are positive for S100 and SOX10, indicating a neural tumor.",
"image_path": "8S4LeiO6Bbk_image_76bedbf1-de38-4994-8b90-f18fe5735913.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['dome-shaped papule', 'acral site', 'thick stratum corneum', 'absence of hair follicles', 'fibrovascular core', 'nerve fascicles', 'spindle-shaped cells', 'S100', 'SOX10', 'rudimentary supernumerary digit']",
"noisy_text": " we've got a dome-shaped papule and that the biopsy is from an acral site. Notice that we've got a very very thick stratum corneum and a marked to virtual absence of hair follicles within the specimen. We do have kind of this fibrovascular core and of course in the center of the fibrovascular core here we've got several well-defined nerve fascicles and the spindled cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions",
"corrected_text": " we've got a dome-shaped papule and that the biopsy is from an acral site. Notice that we've got a very very thick stratum corneum and a marked to virtual absence of hair follicles within the specimen. We do have kind of this fibrovascular core and of course in the center of the fibrovascular core here we've got several well-defined nerve fascicles and the spindle cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions",
"med_umls_ids": "[[{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'acral site', 'concept_id': 'C0439746', 'confidence': 0.717435359954834}, {'entity': 'dome-shaped papule', 'concept_id': 'C1711316', 'confidence': 0.752353847026825}], [{'entity': 'specimen', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'stratum corneum', 'concept_id': 'C0221921', 'confidence': 1.0}, {'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'hair follicles', 'concept_id': 'C0221971', 'confidence': 0.9999998807907104}], [{'entity': 'fibrovascular', 'concept_id': 'C0392759', 'confidence': 1.0}, {'entity': 'nerve fascicles', 'concept_id': 'C1185741', 'confidence': 0.8332967758178711}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'S100', 'concept_id': 'C3273837', 'confidence': 1.0}, {'entity': 'SOX10', 'concept_id': 'C1420317', 'confidence': 0.9999998807907104}, {'entity': 'neural tumor', 'concept_id': 'C1334956', 'confidence': 1.0}], [{'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'rudimentary supernumerary digit', 'concept_id': 'C0152427', 'confidence': 0.8142021894454956}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_471",
"caption_rating": "9"
},
{
"": "1004517",
"caption": "Increased melanin pigment and dendritic melanocytes within the epidermis.",
"image_path": "8S4LeiO6Bbk_image_e36ae543-beb6-4d14-b8f4-ce18475d9a62.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['abnormal maturation of keratinocytes', 'hyperchromatic cells', 'melanin pigment', 'dendritic melanocytes']",
"noisy_text": " I think would be reasonable considerations. However, if we move to higher power and begin to study the epidermis a little bit more carefully we can see that there's clear-cut abnormal maturation here. We've got full thickness keratinocytic atypia with nucleic acid or pleomorphic and hyperchromatic. There is abnormal maturation with even abnormal hyperchromatic perikaratotic cells within the stratum corneum. There's an increased amount of melanin pigment pressed within the basal layer and we can see that we've got an increased amount of melanin pigment and even a few dendritic melanocytes within the epidermis and so what we've got here is an example of pigmented Bowen's disease or pigmented squamous cell carcinoma. One could see similar changes in lesions",
"corrected_text": " I think would be reasonable considerations. However, if we move to higher power and begin to study the epidermis a little bit more carefully we can see that there's clear-cut abnormal maturation of keratinocytes here. We've got full thickness keratinocytic atypia with nucleic acid or pleomorphic and hyperchromatic. There is abnormal maturation with even abnormal hyperchromatic parakeratotic cells within the stratum corneum. There's an increased amount of melanin pigment pressed within the basal layer and we can see that we've got an increased amount of melanin pigment and even a few dendritic melanocytes within the epidermis and so what we've got here is an example of pigmented Bowen 's disease's disease or pigmented squamous cell carcinoma. One could see similar changes in lesions",
"med_umls_ids": "[[{'entity': 'Abnormal', 'concept_id': 'C0205161', 'confidence': 1.0}, {'entity': 'maturation', 'concept_id': 'C0678723', 'confidence': 1.0}, {'entity': 'keratinocytes', 'concept_id': 'C0022567', 'confidence': 1.0}, {'entity': 'thickness', 'concept_id': 'C1280412', 'confidence': 1.0}, {'entity': 'keratinocytic atypia', 'concept_id': 'C0741302', 'confidence': 0.6335055828094482}, {'entity': 'hyperchromatic cells', 'concept_id': 'C0333911', 'confidence': 0.823300302028656}, {'entity': 'stratum corneum', 'concept_id': 'C0221921', 'confidence': 1.0}], [{'entity': 'Increased', 'concept_id': 'C0205217', 'confidence': 1.0}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}, {'entity': 'pigment', 'concept_id': 'C0031911', 'confidence': 1.0}, {'entity': 'dendritic melanocytes', 'concept_id': 'C0025201', 'confidence': 0.7694142460823059}, {'entity': 'epidermis', 'concept_id': 'C0014520', 'confidence': 1.0}], [{'entity': 'Diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'Bowen\u2019s disease', 'concept_id': 'C0006079', 'confidence': 0.9730859994888306}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'squamous cell carcinoma', 'concept_id': 'C0007137', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_472",
"caption_rating": "8"
},
{
"": "1004604",
"caption": "Septal and lobular panniculitis are present with distortion of the fat architecture.",
"image_path": "hoV-JkD6Wb0_image_a9954815-75a0-4513-ac9c-cf559c4e861d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['Lesion with induration and yellow periphery', 'Nodular angioplasia in the papillary dermis', 'Septal and lobular panniculitis', 'Distortion of fat architecture', 'Stasis-related vascular change', 'Subcutaneous tissue with few viable adipocytes', 'Lesion with induration and yellow periphery', 'Nodular angioplasia in the papillary dermis', 'Septal and lobular panniculitis', 'Distortion of fat architecture', 'Stasis-related vascular change', 'Subcutaneous tissue with few viable adipocytes']",
"noisy_text": " injurated, looks a little yellow over at the periphery, a little red center light, and a large punch biopsy through this lesion reveals evidence within the papillary dermis of nodular angioplasia, so we have a little bit of stasis-related vascular change, but not much inflammation. In this particular instance, we have a rip-roaring paniculitis here. We have a lobular paniculitis. If you take a look at the fat here, there's total distortion of the architecture, and this is barely discernible as subcutaneous tissue, but there's not a lot of inflammation. There aren't many viable adipocytes left here. A lot of the adipocytes have kind of ruptured and fused,",
"corrected_text": " indurated, looks a little yellow over at the periphery, a little red center light, and a large punch biopsy through this lesion reveals evidence within the papillary dermis of nodular angioplasia, so we have a little bit of stasis-related vascular change, but not much inflammation. In this particular instance, we have a lobular panniculitis here. We have a lobular panniculitis. If you take a look at the fat here, there's total distortion of the architecture, and this is barely discernible as subcutaneous tissue, but there's not a lot of inflammation. There aren't many viable adipocytes left here. A lot of the adipocytes have kind of ruptured and fused,",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'indurated', 'concept_id': 'C0702114', 'confidence': 1.0}, {'entity': 'yellow periphery', 'concept_id': 'C0221205', 'confidence': 0.7174375653266907}, {'entity': 'red center light', 'concept_id': 'C0563227', 'confidence': 0.7959515452384949}], [{'entity': 'Punch biopsy', 'concept_id': 'C0182557', 'confidence': 1.0}, {'entity': 'nodular angioplasia', 'concept_id': 'C0205297', 'confidence': 0.6163609623908997}, {'entity': 'papillary dermis', 'concept_id': 'C0682598', 'confidence': 1.0}], [{'entity': 'Septal', 'concept_id': 'C0442004', 'confidence': 0.9999999403953552}, {'entity': 'lobular panniculitis', 'concept_id': 'C0263012', 'confidence': 1.0}, {'entity': 'distortion', 'concept_id': 'C0332482', 'confidence': 1.0}, {'entity': 'fat architecture', 'concept_id': 'C0003737', 'confidence': 0.88345867395401}], [{'entity': 'stasis-related vascular change', 'concept_id': 'C0005847', 'confidence': 0.522698700428009}, {'entity': 'inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}], [{'entity': 'adipocytes', 'concept_id': 'C0206131', 'confidence': 1.0}, {'entity': 'left', 'concept_id': 'C0205091', 'confidence': 1.0}, {'entity': 'subcutaneous tissue', 'concept_id': 'C0222331', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_473",
"caption_rating": "8"
},
{
"": "1008895",
"caption": "The spindle cells are thin and bland, and can appear oval or round depending on the angle of sectioning.",
"image_path": "QDb68_G1HR4_image_4097825f-1098-41ce-81f2-a72d488bacdf.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['fine delicate thread-like collagen', 'spindle cells', 'perineurioma', 'low-grade fibromyxoid sarcoma', 'whirled or swirled areas']",
"noisy_text": " look at that very fine delicate thread-like collagen in the background, the spindle cells are very thin and bland and sometimes if you depending on which way the cells are kind of sectioned, they can look a little more oval or even round and I think this is similar that's why this tumor one of the mimics that you can see one of the histologic mimics is perineurioma and I have another video about perineurioma that really goes into detail. Perineuriomas often have cells that look very much like this and both perineurioma as well as low-grade fibromyxoid sarcoma can have very whirled or swirled areas. This one's",
"corrected_text": " look at that very fine delicate thread-like collagen in the background, the spindle cells are very thin and bland and sometimes if you depending on which way the cells are kind of sectioned, they can look a little more oval or even round and I think this is similar that's why this tumor one of the mimics that you can see one of the histologic mimics is perineurioma and I have another video about perineurioma that really goes into detail. Perineuriomas often have cells that look very much like this and both perineurioma as well as low-grade fibromyxoid sarcoma can have very whirled or swirled areas. This one's",
"med_umls_ids": "[[{'entity': 'background', 'concept_id': 'C1706907', 'confidence': 1.0}, {'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'delicate', 'concept_id': 'C0241181', 'confidence': 0.7745490074157715}, {'entity': 'thread-like collagen', 'concept_id': 'C1979891', 'confidence': 0.845443606376648}], [{'entity': 'spindle cells', 'concept_id': 'C0682540', 'confidence': 1.0}, {'entity': 'thin', 'concept_id': 'C0205168', 'confidence': 1.0}, {'entity': 'bland', 'concept_id': 'C0227475', 'confidence': 0.7435316443443298}, {'entity': 'oval', 'concept_id': 'C1709367', 'confidence': 1.0}, {'entity': 'round', 'concept_id': 'C0332490', 'confidence': 1.0}, {'entity': 'angle of sectioning', 'concept_id': 'C0700320', 'confidence': 0.7131970524787903}], [{'entity': 'Perineurioma', 'concept_id': 'C0751691', 'confidence': 0.9999999403953552}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'histologic', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'mimics', 'concept_id': 'C0393040', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_474",
"caption_rating": "8"
},
{
"": "1004334",
"caption": "Colonic biopsy showing normal epithelium with a single layer of cells and mucin present.",
"image_path": "r7OA0Trj5hQ_image_84ca4e8c-0f3e-4aeb-92b9-cf2ef6a76171.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['acidic intestinal mucin taking Asian blue color', 'colonic biopsy showing normal epithelium with a single layer of cells and mucin present.', 'acidic intestinal mucin taking Asian blue color', 'colonic biopsy showing normal epithelium with a single layer of cells and mucin present.', 'acidic intestinal mucin taking Asian blue color', 'colonic biopsy showing normal epithelium with a single layer of cells and mucin present.']",
"noisy_text": " the acidic mucin is taking the asian blue color, whereas the gastric mucin is taking the neutral mucin, pink color, PAS. Asian blue stains the acidic intestinal mucin into blue. That is very essential to remember. Here, what is happening? This is a colonic biopsy. You see the normal epithelium, single strand, single epithelium, lot of mucin. Looks normal now, normal. When you travel all along, what's happening here? You see the difference between this and this. Here, single layer of cells, mucin is present, whereas here,",
"corrected_text": " the acidic mucin is taking the asian blue color, whereas the gastric mucin is taking the neutral mucin, pink color, PAS. Asian blue stains the acidic intestinal mucin into blue. That is very essential to remember. Here, what is happening? This is a colonic biopsy. You see the normal epithelium, single strand, single epithelium, lot of mucin. Looks normal now, normal. When you travel all along, what's happening here? You see the difference between this and this. Here, single layer of cells, mucin is present, whereas here,",
"med_umls_ids": "[[{'entity': 'Differentiation', 'concept_id': 'C0007589', 'confidence': 1.0}, {'entity': 'acidic', 'concept_id': 'C0001128', 'confidence': 1.0}, {'entity': 'gastric mucin', 'concept_id': 'C0017135', 'confidence': 1.0}, {'entity': 'Asian blue', 'concept_id': 'C1197245', 'confidence': 0.8144476413726807}, {'entity': 'pink color', 'concept_id': 'C0332585', 'confidence': 0.9999998807907104}, {'entity': 'PAS', 'concept_id': 'C0030125', 'confidence': 1.0}, {'entity': 'stains', 'concept_id': 'C0038128', 'confidence': 1.0}], [{'entity': 'Colonic biopsy', 'concept_id': 'C0192867', 'confidence': 1.0}, {'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'mucin', 'concept_id': 'C0026682', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_475",
"caption_rating": "8"
},
{
"": "1008798",
"caption": "CD68 is strongly positive in xanthoma.",
"image_path": "r7OA0Trj5hQ_image_f8bf80de-fda4-4f96-afa6-e8678c34a8dd.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['young males', 'inflammatory bowel disease', 'lamina propria', 'distinct cell border', 'foamy cytoplasm', 'centrally placed nucleus', 'gastric xanthoma', 'centrally placed nucleus']",
"noisy_text": " It is commonly seen in young males, and they present with the signs and symptoms of inflammatory bowel disease. Interesting condition. Here, the lamina propria is full of cells with a distinct cell border, abundant foamy cytoplasm, most of the time centrally placed nucleus. Sometimes it is pushed to the periphery. The central nuclear placement is very important for a diagnosis of xanthoma. For a signet cells, it will be predominantly peripherally pushed nucleus. And when you have doubt, you do a CD68, which will be strongly positive. And so this is a gastric xanthoma. Here, it",
"corrected_text": " It is commonly seen in young males, and they present with the signs and symptoms of inflammatory bowel disease. Interesting condition. Here, the lamina propria is full of cells with a distinct cell border, abundant foamy cytoplasm, most of the time centrally placed nucleus. Sometimes it is pushed to the periphery. The central nuclear placement is very important for a diagnosis of xanthoma. For a signet ring cells, it will be predominantly peripherally pushed nucleus. And when you have doubt, you do a CD68, which will be strongly positive. And so this is a gastric xanthoma. Here, it",
"med_umls_ids": "[[{'entity': 'Xanthoma', 'concept_id': 'C0302314', 'confidence': 1.0}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'young', 'concept_id': 'C0332239', 'confidence': 1.0}, {'entity': 'males', 'concept_id': 'C0086582', 'confidence': 1.0}, {'entity': 'signs', 'concept_id': 'C0220912', 'confidence': 0.9999999403953552}, {'entity': 'symptoms', 'concept_id': 'C0683368', 'confidence': 1.0}, {'entity': 'inflammatory bowel disease', 'concept_id': 'C0021390', 'confidence': 1.0}], [{'entity': 'Lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'cell border', 'concept_id': 'C0205284', 'confidence': 0.773768424987793}, {'entity': 'foamy cytoplasm', 'concept_id': 'C0010834', 'confidence': 0.7207725048065186}, {'entity': 'centrally', 'concept_id': 'C0205099', 'confidence': 0.7070305943489075}, {'entity': 'nucleus', 'concept_id': 'C0007610', 'confidence': 1.0}, {'entity': 'gastric xanthoma', 'concept_id': 'C1282522', 'confidence': 1.0}], [{'entity': 'CD68', 'concept_id': 'C0108799', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'xanthoma', 'concept_id': 'C0302314', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_476",
"caption_rating": "8"
},
{
"": "1006809",
"caption": "Description of fibromyxoid stroma and diffuse dissection throughout the dermis.",
"image_path": "LlPaENuqzVQ_image_1054f018-0d38-4844-880a-e5d06f34a657.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['Eosinophilic cells with squamous morphology', 'Fibromyxoid stroma', 'Diffuse dissection throughout the dermis', 'Eosinophilic cells with squamous morphology', 'Fibromyxoid stroma', 'Diffuse dissection throughout the dermis']",
"noisy_text": " We have a diagnosis called the surface of the sclerosing epithelial neoplasm. You have to go back and take more, another biopsy. MACs often will have a little more squamoid morphology like this. Can you see those kind of eosinophilic cells? They kind of look a little bit more like squamous cells a little bit. So that favors MAC more than like a desmoplastic tricho or even like a serendoma. A serendoma usually also is obviously much smaller. You can't take a shave biopsy and get an entire serendoma out. And usually the stroma is more prominent in the serendoma. Notice that this stroma is more fibromucinous. So this thing is kind of dissecting diffusely throughout the dermis here. I don't see",
"corrected_text": " We have a diagnosis called the surface of the sclerosing epithelial neoplasm. You have to go back and take more, another biopsy. MACs often will have a little more squamous morphology like this. Can you see those kind of eosinophilic cells? They kind of look a little bit more like squamous cells a little bit. So that favors MAC more than like a desmoplastic tricholemmoma or even like a syringoma. A syringoma usually also is obviously much smaller. You can't take a shave biopsy and get an entire syringoma out. And usually the stroma is more prominent in the syringoma. Notice that this stroma is more fibromyxoid. So this thing is kind of dissecting diffusely throughout the dermis here. I don't see",
"med_umls_ids": "[[{'entity': 'Diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'sclerosing', 'concept_id': 'C0036426', 'confidence': 0.833010733127594}, {'entity': 'epithelial neoplasm', 'concept_id': 'C1368683', 'confidence': 1.0}, {'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}], [{'entity': 'Comparison', 'concept_id': 'C1707455', 'confidence': 1.0}, {'entity': 'squamous', 'concept_id': 'C1182670', 'confidence': 0.9999998807907104}, {'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}, {'entity': 'MAC', 'concept_id': 'C0009545', 'confidence': 0.9999999403953552}, {'entity': 'desmoplastic tricholemmoma', 'concept_id': 'C1275206', 'confidence': 0.9999999403953552}, {'entity': 'syringoma', 'concept_id': 'C0206673', 'confidence': 1.0}], [{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'fibromyxoid', 'concept_id': 'C0205766', 'confidence': 0.8987292051315308}, {'entity': 'stroma', 'concept_id': 'C0927195', 'confidence': 1.0}, {'entity': 'diffuse dissection', 'concept_id': 'C0205219', 'confidence': 0.7718934416770935}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_477",
"caption_rating": "9"
},
{
"": "1006203",
"caption": "The biopsy from the urethra shows urethritis cystica et glandularis, with dissecting pools of mucin that do not necessarily indicate malignancy. Goblet cell formation is visible, indicating the initial stages of mucinous adenocarcinoma.",
"image_path": "iklRyY1nBIE_image_3fe06ba9-e820-454a-b109-7db48ba3427e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['Urethritis cystica et glandularis', 'Goblet cell formation']",
"noisy_text": " So this was a biopsy from the urethra. And all you can see here is urethritis cystica et glandularis. They're dissecting pools of mucin, but that doesn't always mean there's a malignant process going on. So that's something else one needs to be careful about. There are some areas here that are very concerning. But the reason why I'm showing you this slide is just to show you the overlying urethritis cystic ed glandularis intestinal type. You can actually see some goblet cell formation there. So that's how it starts. And then it progresses to this, where you're not just seeing the surface urethelium involved by this misnose adenocarcinoma, but it's actually beginning to invade the subepithelial connective tissue. It's beginning",
"corrected_text": " So this was a biopsy from the urethra. And all you can see here is urethritis cystica et glandularis. They're dissecting pools of mucin, but that doesn't always mean there's a malignant process going on. So that's something else one needs to be careful about. There are some areas here that are very concerning. But the reason why I'm showing you this slide is just to show you the overlying urethritis cystic ed glandularis intestinal type. You can actually see some goblet cell formation there. So that's how it starts. And then it progresses to this, where you're not just seeing the surface urothelium involved by this mucinous adenocarcinoma, but it's actually beginning to invade the lamina propria. It's beginning",
"med_umls_ids": "[[{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'urethra', 'concept_id': 'C0041967', 'confidence': 1.0}, {'entity': 'urethritis cystica', 'concept_id': 'C3272656', 'confidence': 0.9999998807907104}, {'entity': 'glandularis', 'concept_id': 'C1231964', 'confidence': 0.8643958568572998}, {'entity': 'dissecting pools', 'concept_id': 'C0205239', 'confidence': 0.6663767695426941}, {'entity': 'mucin', 'concept_id': 'C0026682', 'confidence': 1.0}, {'entity': 'malignancy', 'concept_id': 'C0006826', 'confidence': 1.0}, {'entity': 'Goblet', 'concept_id': 'C0506994', 'confidence': 0.8473865389823914}, {'entity': 'cell formation', 'concept_id': 'C2936218', 'confidence': 0.9225678443908691}, {'entity': 'visible', 'concept_id': 'C0205379', 'confidence': 0.9999998807907104}, {'entity': 'stages', 'concept_id': 'C1306673', 'confidence': 0.9999999403953552}, {'entity': 'mucinous adenocarcinoma', 'concept_id': 'C0007130', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_478",
"caption_rating": "8"
},
{
"": "1006196",
"caption": "There is loss of the cornified layer.",
"image_path": "udoW6VSqsm4_image_01babf43-1324-4979-a4e0-a40cd4bcf37d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['loss of the cornified layer', 'loss of the cornified layer']",
"noisy_text": " And so, the other things we kind of talked about are a bit differential, but next slide. Nothing else really will give you this kind of localized circumscribed area like this, so it's not poro. That would have a coronal lamella with granulocidal abnormalities and dyskeratonic keratinocytes. We don't see that here, so this is just a loss of the coronified layer. And there's one other condition where you kind of get, where are some other little clonal, you know, somatic mutations that you can get abnormalities in the epithelium that occur just in localized areas. That's not like loss of the coronified layer. We'll put a couple of other diseases where you see just local areas that are abnormal, and you get normal skin to the side. So, poro is one. We'll put",
"corrected_text": " And so, the other things we kind of talked about are a bit differential, but next slide. Nothing else really will give you this kind of localized circumscribed area like this, so it's not poro. That would have a coronal lamella with granulomatous abnormalities and dyskeratotic keratinocytes. We don't see that here, so this is just a loss of the cornified layer. And there's one other condition where you kind of get, where are some other little clonal, you know, somatic mutations that you can get abnormalities in the epithelium that occur just in localized areas. That's not like loss of the cornified layer. We'll put a couple of other diseases where you see just local areas that are abnormal, and you get normal skin to the side. So, poro is one. We'll put",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'localized', 'concept_id': 'C0392752', 'confidence': 1.0}, {'entity': 'circumscribed area', 'concept_id': 'C1282914', 'confidence': 0.9260231852531433}, {'entity': 'granulomatous abnormalities', 'concept_id': 'C0439667', 'confidence': 0.7099277377128601}, {'entity': 'dyskeratotic keratinocytes', 'concept_id': 'C1512099', 'confidence': 0.9701507091522217}, {'entity': 'porokeratosis', 'concept_id': 'C0162839', 'confidence': 1.0}], [{'entity': 'loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'cornified layer', 'concept_id': 'C3554359', 'confidence': 0.8562335968017578}], [{'entity': 'conditions', 'concept_id': 'C0012634', 'confidence': 0.8556983470916748}, {'entity': 'localized', 'concept_id': 'C0392752', 'confidence': 1.0}, {'entity': 'abnormality', 'concept_id': 'C1704258', 'confidence': 1.0}, {'entity': 'somatic mutations', 'concept_id': 'C0544886', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_479",
"caption_rating": "8"
},
{
"": "1005322",
"caption": "Multiple deep shaves or excisional/incisional biopsy described.",
"image_path": "LlPaENuqzVQ_image_e989ed10-d52e-4a88-ac90-7846a71da574.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " All right, who wants to give this one a go? Hello, can you hear me? Yeah. Looks like we have multiple deep shaves. Well, wait a second. You've been in the surgery clinic before and you've done a lot of biopsies in your long career now. So this, you think it's really a shave? I take that back. It's probably excision or incisional biopsy. Yeah, yeah, yes, good. This is an excision. So they basically took the elliptical excision. They cut it into bread loaves and put it all on one slide. So that's how",
"corrected_text": " All right, who wants to give this one a go? Hello, can you hear me? Yeah. Looks like we have multiple deep shaves. Well, wait a second. You've been in the surgery clinic before and you've done a lot of biopsies in your long career now. So this, you think it's really a shave? I take that back. It's probably excision or incisional biopsy. Yeah, yeah, yes, good. This is an excision. So they basically took the elliptical excision. They cut it into bread loaves and put it all on one slide. So that's how",
"med_umls_ids": "[[{'entity': 'Multiple', 'concept_id': 'C0439064', 'confidence': 1.0}, {'entity': 'deep shaves', 'concept_id': 'C0518505', 'confidence': 0.7456271648406982}, {'entity': 'excisional/incisional biopsy', 'concept_id': 'C0184921', 'confidence': 0.7826999425888062}], [{'entity': 'Elliptical excision', 'concept_id': 'C1707902', 'confidence': 0.8901858329772949}, {'entity': 'bread', 'concept_id': 'C0006138', 'confidence': 1.0}, {'entity': 'histological examination', 'concept_id': 'C0019637', 'confidence': 0.9535407423973083}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_480",
"caption_rating": "8"
},
{
"": "1005033",
"caption": "Disseminated GA in older individuals may be a perineoplastic process.",
"image_path": "udoW6VSqsm4_image_30d935c5-5d59-43aa-93d8-cd7cd7b0e1af.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['small individual papules', 'central crust', 'perioral skin', 'granulomatous condition', 'palisade granulostermatitis', 'neutrophilic dermatosis', 'older individuals', 'perineoplastic process']",
"noisy_text": " Yeah, this would be more kind of the classic one, probably. What else? Here's the classic one clinically. What if there's small individual papules that have a central crust in them, often on apral skin? We have had several cases of the disseminated GA, but I'm not sure if they didn't have a crust. So, what's the type that had it? Perforating? Perforating GA. Perforating GA, good. So, this was granulomanuary. There's one other condition that gives you palisade granulostermatitis like this, but it also gives you some neutrophils infiltrate. That palisade and neutrophilic granulostermatitis, that's another thing that you at least have to think about when you see GA. If you see an older person that's got disseminated GA, think about it as a perineoplastic process. Sometimes you",
"corrected_text": " Yeah, this would be more kind of the classic one, probably. What else? Here's the classic one clinically. What if there's small individual papules that have a central crust in them, often on perioral skin? We have had several cases of the disseminated GA, but I'm not sure if they didn't have a crust. So, what's the type that had it? Perforating? Perforating GA. Perforating GA, good. So, this was granulomatous. There's one other condition that gives you palisade granulostermatitis like this, but it also gives you some neutrophils infiltrate. That palisade and neutrophilic dermatosis, that's another thing that you at least have to think about when you see GA. If you see an older person that's got disseminated GA, think about it as a perineoplastic process. Sometimes you",
"med_umls_ids": "[[{'entity': 'Clinical', 'concept_id': 'C0205210', 'confidence': 1.0}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'skin condition', 'concept_id': 'C1719933', 'confidence': 1.0}, {'entity': 'individual', 'concept_id': 'C0027361', 'confidence': 1.0}, {'entity': 'papules', 'concept_id': 'C0332563', 'confidence': 0.9999999403953552}, {'entity': 'central crust', 'concept_id': 'C0205204', 'confidence': 0.7633819580078125}, {'entity': 'perioral skin', 'concept_id': 'C0448802', 'confidence': 0.8075158596038818}], [{'entity': 'Perforating', 'concept_id': 'C0549099', 'confidence': 1.0}, {'entity': 'GA', 'concept_id': 'C0002915', 'confidence': 1.0}, {'entity': 'granulomatous condition', 'concept_id': 'C0439667', 'confidence': 0.8219265341758728}, {'entity': 'palisade', 'concept_id': 'C0331512', 'confidence': 0.8241410255432129}, {'entity': 'granulostermatitis', 'concept_id': 'C0743086', 'confidence': 0.7311265468597412}], [{'entity': 'Neutrophilic dermatosis', 'concept_id': 'C1142272', 'confidence': 1.0}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'GA', 'concept_id': 'C0002915', 'confidence': 1.0}], [{'entity': 'Disseminated', 'concept_id': 'C0205221', 'confidence': 1.0}, {'entity': 'GA', 'concept_id': 'C0002915', 'confidence': 1.0}, {'entity': 'older', 'concept_id': 'C0337524', 'confidence': 0.7771234512329102}, {'entity': 'individuals', 'concept_id': 'C0027361', 'confidence': 0.8766164779663086}, {'entity': 'perineoplastic process', 'concept_id': 'C0027671', 'confidence': 0.8771522045135498}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_481",
"caption_rating": "8"
},
{
"": "1006802",
"caption": "Description of a cocktail of markers used for intraductal carcinoma of the prostate diagnosis.",
"image_path": "iklRyY1nBIE_image_06474144-5c48-46a7-8e65-c93b6249c886.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['basal cells at the periphery', 'enlarged nuclei', 'intraductal carcinoma of the prostate', 'adjacent invasive tumor', 'previously benign gland', 'basal cells at the periphery', 'enlarged nuclei', 'intraductal carcinoma of the prostate', 'adjacent invasive tumor', 'previously benign gland']",
"noisy_text": " Let me show you what the cocktail looks like. Again, this is the pin three, or some call it pin four. You have the P63, you have the hemoglobin cytokeratin, and then you have the racemase, which is the pink chromogen. And as you can see, as I demonstrated on the H&E, basal cells are indeed present. This is too much for high-grade pin. This is basically what is called a solid cribriform kind of pattern, in which over 50% of the lumen is filled by tumor cells. So this is way too much for high-grade pin. But it's not invasive, because you have basal cells at the periphery. And the nuclei are enlarged. These nuclei are about six times the size of normal prostate nuclei. So this case meets the criteria for introductal carcinoma of the prostate. There is an invasive component, which you can see is negative for basal cell markers. But you have the introductal component. And this is a very interesting entity. The vast majority of cases, and I'll show you the corresponding radical prostatectomy specimens in a second, but the vast majority of these so-called introductal carcinoma of the prostate is due to invasion, colonization by adjacent invasive tumor. And it usually occurs in patients that have high-volume tumors. When I show you the corresponding radical prostatectomies, you'll see what I'm talking about. You usually don't have this in patients in their radicals that have 5% prostate cancer or 10% prostate cancer. It's usually patients that have extensive prostate cancer involvement, and the invasive glands basically have nowhere else to go but to colonize adjacent benign glands. And I'll demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues,",
"corrected_text": " Let me show you what the cocktail looks like. Again, this is the pin three, or some call it pin four. You have the P63, you have the hemoglobin cytokeratin, and then you have the racemase, which is the AMACR. And as you can see, as I demonstrated on the H&E, basal cells are indeed present. This is too much for high-grade pin. This is basically what is called a solid cribriform kind of pattern, in which over 50% of the lumen is filled by tumor cells. So this is way too much for high-grade pin. But it's not invasive, because you have basal cells at the periphery. And the nuclei are enlarged. These nuclei are about six times the size of normal prostate nuclei. So this case meets the criteria for intraductal carcinoma of the prostate. There is an invasive component, which you can see is negative for basal cell markers. But you have the intraductal component. And this is a very interesting entity. The vast majority of cases, and I'll show you the corresponding radical prostatectomy specimens in a second, but the vast majority of these so-called intraductal carcinoma of the prostate is due to invasion, colonization by adjacent invasive tumor. And it usually occurs in patients that have high-volume tumors. When I show you the corresponding radical prostatectomies, you'll see what I'm talking about. You usually don't have this in patients in their radicals that have 5% prostate cancer or 10% prostate cancer. It's usually patients that have extensive prostate cancer involvement, and the invasive glands basically have nowhere else to go but to colonize adjacent benign glands. And I'demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues,",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'cocktail', 'concept_id': 'C0678420', 'confidence': 1.0}, {'entity': 'markers', 'concept_id': 'C0181734', 'confidence': 0.890313982963562}, {'entity': 'intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate diagnosis', 'concept_id': 'C0011900', 'confidence': 0.7927443981170654}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'basal cells', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}], [{'entity': 'Enlarged nuclei', 'concept_id': 'C4013177', 'confidence': 0.7774685621261597}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'normal', 'concept_id': 'C0205307', 'confidence': 1.0}], [{'entity': 'Intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'invasion', 'concept_id': 'C1269955', 'confidence': 1.0}, {'entity': 'colonization', 'concept_id': 'C4289767', 'confidence': 1.0}, {'entity': 'adjacent', 'concept_id': 'C0205117', 'confidence': 1.0}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}], [{'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'benign gland', 'concept_id': 'C0205183', 'confidence': 0.7986565828323364}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_482",
"caption_rating": "7"
},
{
"": "1007946",
"caption": "The tumor is a variation of low-grade fibromyxoid sarcoma, which can be confused with the neuroblastoma-like variant of schwannoma.",
"image_path": "QDb68_G1HR4_image_aacf1417-2253-4b8d-8465-726c7d25bc75.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Big collagen rich rosettes', 'Prominent round cell appearance around the edge of the rim of the nodules', 'Small round blue cells of a neuroblastoma']",
"noisy_text": " It has also big collagen rich rosettes like this but it has a much more prominent round cell appearance around the edge of the rim of the nodules are very like small round blue cell almost look a little bit like the small round blue cells of a neuroblastoma which is why it's named that way but I've definitely seen pathologists have trouble telling those two apart telling a hyalinizing spindle cell tumor with giant rosettes. This tumor we're looking at here a variation of low-grade fibromyxoid sarcoma I've seen people get that confused with the neuroblastoma-like variant of schwannoma and the difference is important because the schwannoma is even though the name sounds kind of scary is actually benign it has a small round blue cell appearance but it's totally benign variation of schwannoma. S100 should easily solve that problem because S100 would be negative here in low-grade fibromyxoid sarcoma and",
"corrected_text": " It has also big collagen rich rosettes like this but it has a much more prominent round cell appearance around the edge of the rim of the nodules are very like small round blue cell almost look a little bit like the small round blue cells of a neuroblastoma which is why it's named that way but I've definitely seen pathologists have trouble telling those two apart telling a hyalinizing spindle cell tumor with giant rosettes. This tumor we're looking at here a variation of low-grade fibromyxoid sarcoma I've seen people get that confused with the neuroblastoma-like variant of schwannoma and the difference is important because the schwannoma is even though the name sounds kind of scary is actually benign it has a small round blue cell appearance but it's totally benign variation of schwannoma. S100 should easily solve that problem because S100 would be negative here in low-grade fibromyxoid sarcoma and",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'rosettes', 'concept_id': 'C0035863', 'confidence': 0.8847858905792236}, {'entity': 'round cell', 'concept_id': 'C0487470', 'confidence': 1.0}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'edge', 'concept_id': 'C0205154', 'confidence': 1.0}, {'entity': 'rim', 'concept_id': 'C1308727', 'confidence': 1.0}, {'entity': 'nodules', 'concept_id': 'C0028259', 'confidence': 1.0}, {'entity': 'neuroblastoma', 'concept_id': 'C0027819', 'confidence': 1.0}], [{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'variation', 'concept_id': 'C0205419', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'neuroblastoma-like variant of', 'concept_id': 'C1419295', 'confidence': 0.6589864492416382}, {'entity': 'schwannoma', 'concept_id': 'C0027809', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_483",
"caption_rating": "8"
},
{
"": "1007631",
"caption": "The observed cryptitis and crypt abscess suggest inflammation in the area.",
"image_path": "r7OA0Trj5hQ_image_e7c27242-cbd6-4dcd-9835-a28dd29ffa63.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Cryptitis', 'Crypt abscess', 'Variation in gland size, shape, and distribution.']",
"noisy_text": " Remember I told you if you see more than five neutrophils, more than five eosinophils sitting in the lamina propria or more than 15 eosinophils per high power field, that is a eosinophilic gastritis, if it is from the stomach. If it is esophagus, it is eosinophilic esophagitis, eosinophilic entritis, eosinophilic colitis. So eosinophilic gastroenteritis. Here it is a cryptitis and cryptopsis. And the glands are also pushed well apart. The glands are showing variation in size, shape, distribution. So this is chronic colitis with activity.",
"corrected_text": " Remember I told you if you see more than five neutrophils, more than five eosinophils sitting in the lamina propria or more than 15 eosinophils per high power field, that is a eosinophilic gastritis, if it is from the stomach. If it is esophagus, it is eosinophilic esophagitis, eosinophilic enteritis, eosinophilic colitis. So eosinophilic gastroenteritis. Here it is a cryptitis and crypt abscess. And the glands are also pushed well apart. The glands are showing variation in size, shape, distribution. So this is chronic colitis with activity.",
"med_umls_ids": "[[{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'eosinophilic gastritis', 'concept_id': 'C0267154', 'confidence': 1.0}, {'entity': 'esophagitis', 'concept_id': 'C0014868', 'confidence': 1.0}, {'entity': 'enteritis', 'concept_id': 'C0014335', 'confidence': 1.0}, {'entity': 'colitis', 'concept_id': 'C0009319', 'confidence': 1.0}], [{'entity': 'cryptitis', 'concept_id': 'C1394254', 'confidence': 0.9999998807907104}, {'entity': 'crypt', 'concept_id': 'C1880192', 'confidence': 1.0}, {'entity': 'abscess', 'concept_id': 'C0000833', 'confidence': 1.0}, {'entity': 'inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}, {'entity': 'area', 'concept_id': 'C0017446', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_484",
"caption_rating": "8"
},
{
"": "1005806",
"caption": "Neurofibromas may be related to the hyalinization in collagen that is seen around smaller vessels.",
"image_path": "QDb68_G1HR4_image_15576c1f-b05a-4451-b3cb-d77bb99212fd.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " a tiger stripe or palisade looking pattern particularly when you have it on the condenser flipped here you can see this unique collagen pattern in this particular tumor. And I don't know but I kind of suspect that these collagen rosettes may be related to the hyalinization in collagen that we see around smaller vessels like I showed in that tumor the example earlier that this may just be a more dramatic example. Now one other tumor that might enter the differential here is the so-called neuroblastoma-like variant of schwannoma",
"corrected_text": " a tiger stripe or palisade looking pattern particularly when you have it on the condenser flipped here you can see this unique collagen pattern in this particular tumor. And I don't know but I kind of suspect that these collagen rosettes may be related to the hyalinization in collagen that we see around smaller vessels like I showed in that tumor the example earlier that this may just be a more dramatic example. Now one other tumor that might enter the differential here is the so-called neuroblastoma-like variant of schwannoma",
"med_umls_ids": "[[{'entity': 'Neurofibromas', 'concept_id': 'C0027830', 'confidence': 1.0}, {'entity': 'hyalinization', 'concept_id': 'C0333438', 'confidence': 1.0}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'vessels', 'concept_id': 'C0005847', 'confidence': 1.0}], [{'entity': 'tiger stripe', 'concept_id': 'C0325115', 'confidence': 0.6842453479766846}, {'entity': 'palisade', 'concept_id': 'C0331512', 'confidence': 0.8241410255432129}, {'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}, {'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'neurofibromas', 'concept_id': 'C0027830', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_485",
"caption_rating": "8"
},
{
"": "1007251",
"caption": "The narrator mentions cellular intramuscular myxoma and the challenges in differentiating it from fibrous and more cellular areas.",
"image_path": "QDb68_G1HR4_image_bdc636a4-5955-45d6-9463-7f5bb403406a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['myxoid features', 'fine delicate collagen', 'cellular intramuscular myxoma', 'fibrous areas', 'cellular areas', 'MUC4 stain']",
"noisy_text": " Here's again the myxoid background I really think this is very helpful. The very very fine delicate collagen that you see. Now areas like this I think can kind of resemble what you see in a so-called cellular intramuscular myxoma. Intramuscular myxomas are usually very blue and myxoid very hypocellular but sometimes they get more fibrous and more cellular areas. And on a needle biopsy I think that can be challenging. So I think usually with some experience you can tell them apart on H and E most of the time but when I have any doubt I just do a MUC4 stain. The MUC4 is negative and on a needle it looks like a myxoma with some kind of fibrous or a little bit more cellular areas and then I just say that it's probably a cellular intramuscular myxoma. So I think MUC4",
"corrected_text": " Here's again the myxoid background I really think this is very helpful. The very very fine delicate collagen that you see. Now areas like this I think can kind of resemble what you see in a so-called cellular intramuscular myxoma. Intramuscular myxomas are usually very blue and myxoid very hypocellular but sometimes they get more fibrous and more cellular areas. And on a needle biopsy I think that can be challenging. So I think usually with some experience you can tell them apart on H and E most of the time but when I have any doubt I just do a MUC4 stain. The MUC4 is negative and on a needle it looks like a myxoma with some kind of fibrous or a little bit more cellular areas and then I just say that it's probably a cellular intramuscular myxoma. So I think MUC4",
"med_umls_ids": "[[{'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'myxoid', 'concept_id': 'C0205295', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}], [{'entity': 'narrator', 'concept_id': 'C1135957', 'confidence': 0.7711340188980103}, {'entity': 'cellular', 'concept_id': 'C0007634', 'confidence': 0.9999999403953552}, {'entity': 'intramuscular', 'concept_id': 'C0442117', 'confidence': 1.0}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}, {'entity': 'cellular areas', 'concept_id': 'C0007634', 'confidence': 0.7882957458496094}], [{'entity': 'MUC4', 'concept_id': 'C1417496', 'confidence': 0.9999999403953552}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'confirm', 'concept_id': 'C0521093', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'cellular intramuscular myxoma', 'concept_id': 'C1334260', 'confidence': 0.8910117149353027}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_486",
"caption_rating": "8"
},
{
"": "1004548",
"caption": "There is loss of the cornified layer.",
"image_path": "udoW6VSqsm4_image_e29262c3-0d70-4b0a-a6c2-41a0befaa599.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['loss of the cornified layer']",
"noisy_text": " And so, the other things we kind of talked about are a bit differential, but next slide. Nothing else really will give you this kind of localized circumscribed area like this, so it's not poro. That would have a coronal lamella with granulocidal abnormalities and dyskeratonic keratinocytes. We don't see that here, so this is just a loss of the coronified layer. And there's one other condition where you kind of get, where are some other little clonal, you know, somatic mutations that you can get abnormalities in the epithelium that occur just in localized areas. That's not like loss of the coronified layer. We'll put a couple of other diseases where you see just local areas that are abnormal, and you get normal skin to the side. So, poro is one. We'll put",
"corrected_text": " And so, the other things we kind of talked about are a bit differential, but next slide. Nothing else really will give you this kind of localized circumscribed area like this, so it's not poro. That would have a coronal lamella with granulomatous abnormalities and dyskeratotic keratinocytes. We don't see that here, so this is just a loss of the cornified layer. And there's one other condition where you kind of get, where are some other little clonal, you know, somatic mutations that you can get abnormalities in the epithelium that occur just in localized areas. That's not like loss of the cornified layer. We'll put a couple of other diseases where you see just local areas that are abnormal, and you get normal skin to the side. So, poro is one. We'll put",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'localized', 'concept_id': 'C0392752', 'confidence': 1.0}, {'entity': 'circumscribed area', 'concept_id': 'C1282914', 'confidence': 0.9260231852531433}, {'entity': 'granulomatous abnormalities', 'concept_id': 'C0439667', 'confidence': 0.7099277377128601}, {'entity': 'dyskeratotic keratinocytes', 'concept_id': 'C1512099', 'confidence': 0.9701507091522217}, {'entity': 'porokeratosis', 'concept_id': 'C0162839', 'confidence': 1.0}], [{'entity': 'loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'cornified layer', 'concept_id': 'C3554359', 'confidence': 0.8562335968017578}], [{'entity': 'conditions', 'concept_id': 'C0012634', 'confidence': 0.8556983470916748}, {'entity': 'localized', 'concept_id': 'C0392752', 'confidence': 1.0}, {'entity': 'abnormality', 'concept_id': 'C1704258', 'confidence': 1.0}, {'entity': 'somatic mutations', 'concept_id': 'C0544886', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_487",
"caption_rating": "8"
},
{
"": "1004576",
"caption": "The lesion is a small benign papule with dilated blood vessels and proliferating sebaceous lobules. It has two components: a fibrous component and an epithelial component, which includes an epithelial sebaceous gland.",
"image_path": "LlPaENuqzVQ_image_cae41cbd-290a-4198-9071-bd865fd42899.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['dilated blood vessels', 'sebaceous lobules', 'fibrous component', 'epithelial component', 'epithelial sebaceous gland', 'teensy small follicle', 'dilated blood vessels', 'sebaceous lobules', 'fibrous component', 'epithelial component', 'epithelial sebaceous gland', 'teensy small follicle']",
"noisy_text": " And then there's some dilated blood vessels and whatnot, background sebaceous lobules that are proliferating. This may be kind of an incipient one of them, but this is what we're looking at here. So it's a small teensy tiny papule. And it's, if it's a neoplasm, it's got a two components to it. It's got a fibrous component, like right here. And then it's also got this epithelial component. What do you think this, what kind of differentiation are we looking at right here? Right, I feel it, right. So this is epithelial sebaceous gland. That's epithelium, little teensy small follicle right there. What's this? Is it closer to this or this? Sorry. Like, it",
"corrected_text": " And then there's some dilated blood vessels and whatnot, background sebaceous lobules that are proliferating. This may be kind of an incipient one of them, but this is what we're looking at here. So it's a small teensy tiny papule. And it's, if it's a neoplasm, it's got a two components to it. It's got a fibrous component, like right here. And then it's also got this epithelial component. What do you think this, what kind of differentiation are we looking at right here? Right, I feel it, right. So this is epithelial sebaceous gland. That's epithelium, little teensy small follicle right there. What's this? Is it closer to this or this? Sorry. Like, it",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'benign papule', 'concept_id': 'C0205183', 'confidence': 0.7019047737121582}, {'entity': 'dilated blood vessels', 'concept_id': 'C0424830', 'confidence': 1.0}, {'entity': 'proliferating sebaceous lobules', 'concept_id': 'C0221946', 'confidence': 0.7654090523719788}, {'entity': 'components', 'concept_id': 'C0449432', 'confidence': 1.0}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}, {'entity': 'epithelial component', 'concept_id': 'C1707933', 'confidence': 0.8783122897148132}, {'entity': 'epithelial sebaceous gland', 'concept_id': 'C0036505', 'confidence': 0.7906183004379272}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_488",
"caption_rating": "9"
},
{
"": "1006604",
"caption": "Identification of different types of protein fibers in connective tissue.",
"image_path": "ib991vTA67A_image_6188c669-9bfe-474b-a77d-2f7eb9650e23.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Head and Neck']",
"roi_text": "['Connective Tissue', 'skinny collagen fibers', 'fat, fatter, thick, pink protein fibers', 'Connective Tissue', 'skinny collagen fibers', 'fat, fatter, thick, pink protein fibers', 'Connective Tissue', 'skinny collagen fibers', 'fat, fatter, thick, pink protein fibers']",
"noisy_text": " and three places where you could find this type of Connective Tissue. So here's this Connective Tissue again, just write it down, and the next question is what type of protein fibers are these skinny ones, these skinny hair-like protein fibers? Find those protein fibers first, the skinny hair-like protein fibers, what are those called? And next, what are these fat, fatter, thick, pink protein fibers called? What are these protein fibers called? Here's a close-up of a Connective Tissue you've seen, so this is going to be number twenty-four, what type",
"corrected_text": " and three places where you could find this type of Connective Tissue. So here's this Connective Tissue again, just write it down, and the next question is what type of protein fibers are these skinny ones, these skinny hair-like protein fibers? Find those protein fibers first, the skinny hair-like protein fibers, what are those called? And next, what are these fat, fatter, thick, pink protein fibers called? What are these protein fibers called? Here's a close-up of a Connective Tissue you've seen, so this is going to be number twenty-four, what type",
"med_umls_ids": "[[{'entity': 'Identification', 'concept_id': 'C0020792', 'confidence': 1.0}, {'entity': 'protein fibers', 'concept_id': 'C0000696', 'confidence': 0.7645217180252075}, {'entity': 'connective tissue', 'concept_id': 'C0009780', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1152.0",
"id": "test_489",
"caption_rating": "8"
},
{
"": "1004572",
"caption": "Intraglandular epithelial proliferation is a feature of high-grade dysplasia.",
"image_path": "r7OA0Trj5hQ_image_3ab9b09a-230e-4d73-8ba3-400b1477d871.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Stroma running in between', 'Crowded appearance', 'Back-to-back glands', 'Cribriform appearance', 'Intraglandular epithelial proliferation', 'Stroma running in between', 'Crowded appearance', 'Back-to-back glands', 'Cribriform appearance', 'Intraglandular epithelial proliferation']",
"noisy_text": " you can see some stroma running in between. However, it may be crowded. See here, one gland, another gland. You can see the nice stroma in between. These are back-to-back glands. But see here, this is one gland, this is one gland, this is one gland. But no stroma in between. So these are cribriform, which is intraglandular. Epithelial proliferation is happening within the gland, which is a future of high-grade dysplasia. So normal epithelium, low-grade dysplasia, high-grade dysplasia in one picture. Thanks to Google. I don't know the source, but I thank the person, anonymous person. So those are",
"corrected_text": " you can see some stroma running in between. However, it may be crowded. See here, one gland, another gland. You can see the nice stroma in between. These are back-to-back glands. But see here, this is one gland, this is one gland, this is one gland. But no stroma in between. So these are cribriform, which is intraglandular. Epithelial proliferation is happening within the gland, which is a future of high-grade dysplasia. So normal epithelium, low-grade dysplasia, high-grade dysplasia in one picture. Thanks to Google. I don't know the source, but I thank the person, anonymous person. So those are",
"med_umls_ids": "[[{'entity': 'Intraglandular', 'concept_id': 'C4725341', 'confidence': 0.9096097350120544}, {'entity': 'epithelial proliferation', 'concept_id': 'C0334097', 'confidence': 1.0}, {'entity': 'high-grade dysplasia', 'concept_id': 'C1333110', 'confidence': 0.8831341862678528}], [{'entity': 'Normal epithelium', 'concept_id': 'C0014609', 'confidence': 0.8199569582939148}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'dysplasia', 'concept_id': 'C0334044', 'confidence': 1.0}, {'entity': 'high-grade dysplasia', 'concept_id': 'C1333110', 'confidence': 0.8831341862678528}, {'entity': 'picture', 'concept_id': 'C0441468', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_490",
"caption_rating": "9"
},
{
"": "1006222",
"caption": "Absence of plasma cells within the infiltrate helps to differentiate this condition from Kaposi sarcoma.",
"image_path": "8S4LeiO6Bbk_image_b3ec906b-b05a-40da-9d74-1e3853522bce.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['papillary projections', 'extravasated erythrocytes', 'dilated vessels', 'enlarged endothelial cells', 'collagen bundles', 'pre-existing vascular spaces', 'papillary projections', 'extravasated erythrocytes', 'dilated vessels', 'enlarged endothelial cells', 'collagen bundles', 'pre-existing vascular spaces']",
"noisy_text": " into the limina. If you look around, you can see these papillary projections. There are a few extravasated erythrocytes present within the stroma. So clearly, we've got this vascular neoplasma here with these dilated endothelial line spaces, but it's got kind of a bifasic pattern. Centrally, we've got these dilated vessels, but peripheral and beneath that zone, the vessels are somewhat more compressed. They're still lined by some of the plump endothelial cells. And in these various where the vessels are compressed, they kind of appear to dissect between collagen bundles. We even have a little bit of a promontory sign here where we've got these vessels surrounding pre-existing vascular spaces. But unlike the neovascular spaces that we see in Kaposi's sarcoma, the endothelial cells here are a little more plump, and we don't have plasma cells within the infiltrate. And plasma cells within the infiltrate can be very useful in discriminating between this condition and Kaposi's sarcoma. In this particular case, also the HHV8 stain was a negative, which",
"corrected_text": " into the limina. If you look around, you can see these papillary projections. There are a few extravasated erythrocytes present within the stroma. So clearly, we've got this vascular neoplasm here with these dilated endothelial line spaces, but it's got kind of a biphasic pattern. Centrally, we've got these dilated vessels, but peripheral and beneath that zone, the vessels are somewhat more compressed. They're still lined by some of the enlarged endothelial cells. And in these various where the vessels are compressed, they kind of appear to dissect between collagen bundles. We even have a little bit of a promontory sign here where we've got these vessels surrounding pre-existing vascular spaces. But unlike the neovascularization that we see in Kaposi's sarcoma, the endothelial cells here are a little more plump, and we don't have plasma cells within the infiltrate. And plasma cells within the infiltrate can be very useful in discriminating between this condition and Kaposi's sarcoma. In this particular case, also the HHV8 stain was a negative, which",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'vascular neoplasm', 'concept_id': 'C0027668', 'confidence': 1.0}, {'entity': 'dilated endothelial line spaces', 'concept_id': 'C0014257', 'confidence': 0.6450937390327454}, {'entity': 'biphasic pattern', 'concept_id': 'C1332555', 'confidence': 1.0}], [{'entity': 'Vessels', 'concept_id': 'C0005847', 'confidence': 1.0}, {'entity': 'peripheral', 'concept_id': 'C0205100', 'confidence': 1.0}, {'entity': 'central zone', 'concept_id': 'C0458698', 'confidence': 1.0}], [{'entity': 'Endothelial cells', 'concept_id': 'C0225336', 'confidence': 1.0}, {'entity': 'enlarged', 'concept_id': 'C0442800', 'confidence': 1.0}, {'entity': 'plump', 'concept_id': 'C1836543', 'confidence': 0.7694027423858643}], [{'entity': 'Absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'differentiate', 'concept_id': 'C0205615', 'confidence': 0.9999998807907104}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'Kaposi sarcoma', 'concept_id': 'C0036220', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "758.0",
"width": "1920.0",
"id": "test_491",
"caption_rating": "8"
},
{
"": "1009163",
"caption": "Squamous morphology is often seen in MAC.",
"image_path": "LlPaENuqzVQ_image_b1297ed1-a8ed-4620-b33e-62d5b1a42cca.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " it'd be very difficult to make a definitive diagnosis. If you just had this, you're sort of SOL. That's why you got to take a deeper biopsy for MAC because that diagnosis is based on the depth of involvement. And you've got to see this kind of pattern to make a definitive diagnosis. So we all have shave biopsies of these. We have a diagnosis called the surface of the sclerosing epithelial neoplasm. You have to go back and take more, another biopsy. MACs often will have a little more squamoid morphology like this. Can you see those kind of eosinophilic cells? They kind of look a little bit more like squamous cells a little bit. So that favors MAC more than like a desmoplastic tricho or even",
"corrected_text": " it'd be very difficult to make a definitive diagnosis. If you just had this, you're sort of SOL. That's why you got to take a deeper biopsy for MAC because that diagnosis is based on the depth of involvement. And you've got to see this kind of pattern to make a definitive diagnosis. So we all have shave biopsies of these. We have a diagnosis called the surface of the sclerosing epithelial neoplasm. You have to go back and take more, another biopsy. MACs often will have a little more squamous morphology like this. Can you see those kind of eosinophilic cells? They kind of look a little bit more like squamous cells a little bit. So that favors MAC more than like a desmoplastic trichilemmoma or even",
"med_umls_ids": "[[{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'MAC', 'concept_id': 'C0009545', 'confidence': 0.9999999403953552}, {'entity': 'Morpheaform Basal Cell Carcinoma', 'concept_id': 'C0555191', 'confidence': 0.9999999403953552}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'depth', 'concept_id': 'C0205125', 'confidence': 1.0}, {'entity': 'involvement', 'concept_id': 'C1314939', 'confidence': 1.0}], [{'entity': 'Squamous', 'concept_id': 'C1182670', 'confidence': 0.9999998807907104}, {'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}, {'entity': 'MAC', 'concept_id': 'C0009545', 'confidence': 0.9999999403953552}], [{'entity': 'Eosinophilic cells', 'concept_id': 'C0682547', 'confidence': 0.8770456314086914}, {'entity': 'MAC', 'concept_id': 'C0009545', 'confidence': 0.9999999403953552}, {'entity': 'squamous cells', 'concept_id': 'C0221910', 'confidence': 0.9999998807907104}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_492",
"caption_rating": "7"
},
{
"": "1006925",
"caption": "The tumor is identified as serous cyst adenocarcinoma due to the characteristic features of atypia, infiltration, and malignant behavior.",
"image_path": "3mRB9j0eyVM_image_a564e201-b229-4bf5-9c1f-ede3903c371b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gynecologic', 'Hematopathology', 'Soft tissue']",
"roi_text": "['atypia', 'infiltrated the underlying stroma', 'solid looking tumor', 'lining epithelial cells', 'infiltrative pattern', 'malignant tumor', 'invasive pattern', 'calcified body', 'rounded calcified bodies', 'papillary configuration', 'papillary structures', 'psammoma bodies']",
"noisy_text": " they will they will be infiltrative pattern, invasive pattern of the tumor, solid looking tumor with you can see here again, pepillary structures are very clearly seen even in the here. This is the picture of serous cyst adenocarcinoma, why we are saying it is carcinoma? Because the lining epithelial cells they have these they have the characteristic feature of atypia, atypia we all know hyperchromatism, pleomorphism, atypical mitotic activity, high MC ratio all these features are seen in these cells along with infiltration. These cells they have infiltrated the underlying stroma, when they have infiltrated the underlying stroma we call this is a malignant tumor, this is serous cyst adenocarcinoma. Now we come to the most common presentation of the serous cyst adenocarcinoma that is pepillary. So most of these tumors they show pepillary configuration that is their cells the epithelial cells they are found in the they form the pepillary configuration and that pepillae then ultimately they invade and they result in the invasiveness. And we all know that the serous cyst pepillary carcinoma we these adenocarcinoma of the ovary this frequently is associated with presence of somoma bodies and what is somoma body you all know from your 3rd year lectures and it was very frequently asked in your viva questions also in your viva examination also that somoma body is a calcified body, rounded calcified bodies are the somoma bodies and these are the typical features or typical findings that are commonly seen in the pepillary serous cyst adenocarcinoma of the ovary. Now we come to the mucinous tumors, again the mucinous tumors are again categorized in mucinous",
"corrected_text": " they will they will be infiltrative pattern, invasive pattern of the tumor, solid looking tumor with you can see here again, papillary structures are very clearly seen even in the here. This is the picture of serous cyst adenocarcinoma, why we are saying it is carcinoma? Because the lining epithelial cells they have these they have the characteristic feature of atypia, atypia we all know hyperchromatism, pleomorphism, atypical mitotic activity, high MC ratio all these features are seen in these cells along with infiltration. These cells they have infiltrated the underlying stroma, when they have infiltrated the underlying stroma we call this is a malignant tumor, this is serous cyst adenocarcinoma. Now we come to the most common presentation of the serous cyst adenocarcinoma that is papillary. So most of these tumors they show papillary configuration that is their cells the epithelial cells they are found in the they form the papillary configuration and that papillae then ultimately they invade and they result in the invasiveness. And we all know that the serous cyst papillary carcinoma we these adenocarcinoma of the ovary this frequently is associated with presence of psammoma bodies and what is somoma body you all know from your 3rd year lectures and it was very frequently asked in your viva questions also in your viva examination also that somoma body is a calcified body, rounded calcified bodies are the psammoma bodies and these are the typical features or typical findings that are commonly seen in the papillary serous cyst adenocarcinoma of the ovary. Now we come to the mucinous tumors, again the mucinous tumors are again categorized in mucinous",
"med_umls_ids": "[[{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'infiltrative', 'concept_id': 'C4527217', 'confidence': 1.0}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}, {'entity': 'solid', 'concept_id': 'C0205208', 'confidence': 1.0}, {'entity': 'papillary structures', 'concept_id': 'C0030352', 'confidence': 0.7890171408653259}], [{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'serous cyst adenocarcinoma', 'concept_id': 'C0206701', 'confidence': 0.8984156847000122}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'atypia', 'concept_id': 'C0741302', 'confidence': 0.9999999403953552}, {'entity': 'infiltration', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'malignant behavior', 'concept_id': 'C0004927', 'confidence': 0.7649628520011902}], [{'entity': 'Papillary configuration', 'concept_id': 'C1276436', 'confidence': 0.9154161214828491}, {'entity': 'presentation', 'concept_id': 'C0449450', 'confidence': 1.0}, {'entity': 'serous cyst adenocarcinoma', 'concept_id': 'C0206701', 'confidence': 0.8984156847000122}], [{'entity': 'Serous cyst papillary carcinoma', 'concept_id': 'C3839184', 'confidence': 0.9130419492721558}, {'entity': 'associated with', 'concept_id': 'C0332281', 'confidence': 1.0}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'psammoma bodies', 'concept_id': 'C0391863', 'confidence': 1.0}, {'entity': 'calcified rounded bodies', 'concept_id': 'C0175895', 'confidence': 0.645065188407898}]]",
"magnification": "1.0",
"height": "720.0",
"width": "960.0",
"id": "test_493",
"caption_rating": "9"
},
{
"": "1007835",
"caption": "Fibroblasts are responsible for producing the protein fibers in connective tissue.",
"image_path": "ib991vTA67A_image_3d5ac809-c102-4ef5-80a0-7c8c842587f1.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Head and Neck']",
"roi_text": "['Fibrocartilage in the knee']",
"noisy_text": " of cartilage that we have in our knee, strong fibrocardilage, fibrocardilage, we have once again, this is a realer connective tissue, the pick up sticks pattern, what type of protein fiber is this? The skinny one, this hair like one, looks like this skinny hair like protein fibers, that's elastic protein fibers, the thick pink ones are collagen protein fibers. There are reticular protein fibers in here, but you cannot see them because you need a special stain, but a realer connective tissue has all three protein fibers in equal numbers, remember they're made by, what kind of cell? Fibroblasts, this is loose connective tissue proper, yes, and then we have this guy, this is once again dense regular, the collagen protein fibers are arranged in a parallel fashion, this is",
"corrected_text": " of cartilage that we have in our knee, strong fibrocartilage, fibrocartilage, we have once again, this is a realer connective tissue, the pick up sticks pattern, what type of protein fiber is this? The skinny one, this hair like one, looks like this skinny hair like protein fibers, that's elastic protein fibers, the thick pink ones are collagen protein fibers. There are reticular protein fibers in here, but you cannot see them because you need a special stain, but a realer connective tissue has all three protein fibers in equal numbers, remember they're made by, what kind of cell? Fibroblasts, this is loose connective tissue proper, yes, and then we have this guy, this is once again dense regular, the collagen protein fibers are arranged in a parallel fashion, this is",
"med_umls_ids": "[[{'entity': 'knee', 'concept_id': 'C0022742', 'confidence': 1.0}, {'entity': 'fibrocartilage', 'concept_id': 'C0684077', 'confidence': 1.0}, {'entity': 'pick-up sticks pattern', 'concept_id': 'C0581683', 'confidence': 0.6339322328567505}, {'entity': 'elastic', 'concept_id': 'C0681018', 'confidence': 1.0}, {'entity': 'collagen protein fibers', 'concept_id': 'C0225325', 'confidence': 0.8096007108688354}], [{'entity': 'Fibroblasts', 'concept_id': 'C0016030', 'confidence': 1.0}, {'entity': 'protein fibers', 'concept_id': 'C0000696', 'confidence': 0.7645217180252075}, {'entity': 'connective tissue', 'concept_id': 'C0009780', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1152.0",
"id": "test_494",
"caption_rating": "7"
},
{
"": "1008900",
"caption": "DFSP is usually in the skin and rarely involves deep soft tissue.",
"image_path": "QDb68_G1HR4_image_a313915e-be10-4a8c-aad9-4213e6f88f34.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['whirling pattern']",
"noisy_text": " This one's not really showing that but some of them do, they have a lot of whirling pattern. So the two other things that keep in the differential here are perineurioma and also dermatofibrosarcoma protuberans, DFSP, which also has a tends to have a story form or whirled and swirled growth pattern and also has a translocation sarcoma, has very bland spindle cells. Okay, I guess I don't have any immunostains with me to show you today but just briefly the immunostains, most of the immunostains that we use for soft tissue tumors are negative most of the time in low-grade fibromyxoid sarcoma. CD34 is usually negative which is a pretty easy way to separate this from DFSP. The other thing is that low-grade fibromyxoid sarcoma usually is a relatively larger and deep, deep soft tissue below the fascia mass, although there are rare examples that are small and superficial and those seem to be more common in children. But DFSP is essentially always in the skin, the dermis or subcutaneous and rarely ever involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is",
"corrected_text": " This one's not really showing that but some of them do, they have a lot of whirling pattern. So the two other things that keep in the differential here are perineurioma and also dermatofibrosarcoma protuberans, DFSP, which also has a tends to have a story form or whirled and swirled growth pattern and also has a translocation sarcoma, has very bland spindle cells. Okay, I guess I don't have any immunostaining with me to show you today but just briefly the immunostaining, most of the immunostaining that we use for soft tissue tumors are negative most of the time in low-grade fibromyxoid sarcoma. CD34 is usually negative which is a pretty easy way to separate this from DFSP. The other thing is that low-grade fibromyxoid sarcoma usually is a relatively larger and deep, deep soft tissue below the fascia mass, although there are rare examples that are small and superficial and those seem to be more common in children. But DFSP is essentially always in the skin, the dermis or subcutaneous and rarely ever involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is",
"med_umls_ids": "[[{'entity': 'Whirling pattern', 'concept_id': 'C0449774', 'confidence': 0.6110570430755615}, {'entity': 'perineurioma', 'concept_id': 'C0751691', 'confidence': 0.9999999403953552}, {'entity': 'dermatofibrosarcoma protuberans', 'concept_id': 'C0206647', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}], [{'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}, {'entity': 'skin', 'concept_id': 'C0444099', 'confidence': 1.0}, {'entity': 'deep soft tissue', 'concept_id': 'C0225317', 'confidence': 0.7996832728385925}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_495",
"caption_rating": "8"
},
{
"": "1007540",
"caption": "Identification of small cell carcinoma with necrosis.",
"image_path": "iklRyY1nBIE_image_27eb32f0-f4c5-433c-a8c2-0391c7ec9b53.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['Adjacent high-grade prostate cancer', 'Small cell carcinoma with necrosis', 'Urethral carcinoma']",
"noisy_text": " If you look very carefully, you can see this adjacent high-grade prostate cancer next door, which basically undergoes de-differentiation, just like you can have with urethral carcinoma. When you have a high-grade urethral carcinoma de-differentiated into small cell, you can have the same thing occurring in the prostate. So it's very important to recognize this. So this is small cell carcinoma. I can appreciate the amount of necrosis. It looks identical to what you see in the lung. Our lung pathology colleagues who are watching this would appreciate that. This",
"corrected_text": " If you look very carefully, you can see this adjacent high-grade prostate cancer next door, which basically undergoes dedifferentiation, just like you can have with urethral carcinoma. When you have a high-grade urethral carcinoma de-differentiated into small cell, you can have the same thing occurring in the prostate. So it's very important to recognize this. So this is small cell carcinoma. I can appreciate the amount of necrosis. It looks identical to what you see in the lung. Our lung pathology colleagues who are watching this would appreciate that. This",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'dedifferentiation', 'concept_id': 'C0002793', 'confidence': 1.0}, {'entity': 'adjacent', 'concept_id': 'C0205117', 'confidence': 1.0}, {'entity': 'high-grade', 'concept_id': 'C1512433', 'confidence': 0.9347730875015259}, {'entity': 'prostate cancer', 'concept_id': 'C0376358', 'confidence': 1.0}, {'entity': 'similarity', 'concept_id': 'C2348205', 'confidence': 1.0}, {'entity': 'urethral carcinoma', 'concept_id': 'C0700101', 'confidence': 1.0}], [{'entity': 'Identification', 'concept_id': 'C0020792', 'confidence': 1.0}, {'entity': 'small cell carcinoma', 'concept_id': 'C0149925', 'confidence': 1.0}, {'entity': 'necrosis', 'concept_id': 'C0027540', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_496",
"caption_rating": "8"
},
{
"": "1006182",
"caption": "Intraglandular epithelial proliferation is a feature of high-grade dysplasia.",
"image_path": "r7OA0Trj5hQ_image_db9604e5-bd2a-49f1-ba3b-c70944238020.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Back-to-back glands', 'Stroma running in between', 'Crowded appearance', 'Back-to-back glands', 'Cribriform appearance', 'Intraglandular epithelial proliferation']",
"noisy_text": " you can see some stroma running in between. However, it may be crowded. See here, one gland, another gland. You can see the nice stroma in between. These are back-to-back glands. But see here, this is one gland, this is one gland, this is one gland. But no stroma in between. So these are cribriform, which is intraglandular. Epithelial proliferation is happening within the gland, which is a future of high-grade dysplasia. So normal epithelium, low-grade dysplasia, high-grade dysplasia in one picture. Thanks to Google. I don't know the source, but I thank the person, anonymous person. So those are",
"corrected_text": " you can see some stroma running in between. However, it may be crowded. See here, one gland, another gland. You can see the nice stroma in between. These are back-to-back glands. But see here, this is one gland, this is one gland, this is one gland. But no stroma in between. So these are cribriform, which is intraglandular. Epithelial proliferation is happening within the gland, which is a future of high-grade dysplasia. So normal epithelium, low-grade dysplasia, high-grade dysplasia in one picture. Thanks to Google. I don't know the source, but I thank the person, anonymous person. So those are",
"med_umls_ids": "[[{'entity': 'Intraglandular', 'concept_id': 'C4725341', 'confidence': 0.9096097350120544}, {'entity': 'epithelial proliferation', 'concept_id': 'C0334097', 'confidence': 1.0}, {'entity': 'high-grade dysplasia', 'concept_id': 'C1333110', 'confidence': 0.8831341862678528}], [{'entity': 'Normal epithelium', 'concept_id': 'C0014609', 'confidence': 0.8199569582939148}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'dysplasia', 'concept_id': 'C0334044', 'confidence': 1.0}, {'entity': 'high-grade dysplasia', 'concept_id': 'C1333110', 'confidence': 0.8831341862678528}, {'entity': 'picture', 'concept_id': 'C0441468', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_497",
"caption_rating": "9"
},
{
"": "1006664",
"caption": "The stain for CMV was positive, despite the absence of cytomegalic cells.",
"image_path": "sDFjOtMAYrk_image_35239e77-655a-460b-b8bd-f010e24f88f8.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "[]",
"noisy_text": " it just didn't make sense for a patient with IBD to have this many just apoptotic micro abscesses. And I thought, well, maybe this is CMV, but I don't see the viral cytopathic changes. But lo and behold, the stain was positive. And then I went back. I went back and said, oh, yeah, there they are there. And there's a there's a more better one. Hold on. Right there, right there. And that's the one that actually lit up on the stain. Yeah, but really what took me off was the apoptosis. I didn't pick up on the on the viral cytopathic changes. Typically,",
"corrected_text": " it just didn't make sense for a patient with IBD to have this many just apoptotic bodies. And I thought, well, maybe this is CMV, but I don't see the viral cytopathic changes. But lo and behold, the stain was positive. And then I went back. I went back and said, oh, yeah, there they are there. And there's a there's a more better one. Hold on. Right there, right there. And that's the one that actually lit up on the stain. Yeah, but really what took me off was the apoptosis. I didn't pick up on the on the viral cytopathic changes. Typically,",
"med_umls_ids": "[[{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'apoptotic bodies', 'concept_id': 'C3269134', 'confidence': 1.0}, {'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'IBD', 'concept_id': 'C0021390', 'confidence': 1.0}], [{'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'CMV', 'concept_id': 'C0010823', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'cytomegalic cells', 'concept_id': 'C0391864', 'confidence': 0.864702582359314}], [{'entity': 'narrator', 'concept_id': 'C1135957', 'confidence': 0.7711340188980103}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'virus', 'concept_id': 'C0042776', 'confidence': 1.0}, {'entity': 'apoptosis', 'concept_id': 'C0162638', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_498",
"caption_rating": "9"
},
{
"": "1006650",
"caption": "Racemase is predominantly negative in prostate cancer.",
"image_path": "iklRyY1nBIE_image_fbc5b269-fc07-4337-8b78-bc8312f6d9b0.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['nuclear stain', 'membranous cytoplasmic stain', 'prostate cancer', 'P63', 'nuclear stain', 'membranous cytoplasmic stain', 'prostate cancer', 'P63']",
"noisy_text": " if you look carefully, is actually negative. The only thing that is positive is a nuclear stain, which is the P63. Again, you want to look at your internal control. These are the glands that were comfortable or benign. You can see they're staining for both nuclear stain and membranous wispy cytoplasmic stain, which is the hemoglobin cytokeratin. In this baccalaureate case, the racemase was predominantly negative. There's a hint of staining in areas, but it's predominantly negative. What is striking, what is very striking, is the fact that the P63 is diffusely positive, which they found very odd. And so this",
"corrected_text": " if you look carefully, is actually negative. The only thing that is positive is a nuclear stain, which is the P63. Again, you want to look at your internal control. These are the glands that were comfortable or benign. You can see they're staining for both nuclear stain and membranous wispy cytoplasmic stain, which is the hemoglobin cytokeratin. In this baccalaureate case, the racemase was predominantly negative. There's a hint of staining in areas, but it's predominantly negative. What is striking, what is very striking, is the fact that the P63 is diffusely positive, which they found very odd. And so this",
"med_umls_ids": "[[{'entity': 'positive stain', 'concept_id': 'C1446409', 'confidence': 0.8016907572746277}, {'entity': 'nuclear stain', 'concept_id': 'C0521447', 'confidence': 0.8163275122642517}, {'entity': 'P63', 'concept_id': 'C1422009', 'confidence': 1.0}], [{'entity': 'internal control glands', 'concept_id': 'C0597937', 'confidence': 0.7678565979003906}, {'entity': 'staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'nuclear', 'concept_id': 'C0521447', 'confidence': 1.0}, {'entity': 'membranous', 'concept_id': 'C0025255', 'confidence': 1.0}], [{'entity': 'Racemase', 'concept_id': 'C0034503', 'confidence': 1.0}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'prostate cancer', 'concept_id': 'C0376358', 'confidence': 1.0}], [{'entity': 'P63', 'concept_id': 'C1422009', 'confidence': 1.0}, {'entity': 'diffusely', 'concept_id': 'C0205219', 'confidence': 0.8011853098869324}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_499",
"caption_rating": "8"
},
{
"": "1009363",
"caption": "Cellular DF with lipid accumulation is commonly located on the ankle of legs and is also known as ankle type DF.",
"image_path": "udoW6VSqsm4_image_98207f81-8fee-42a2-9952-21a4f716c4ab.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['cellular DF with lipid accumulation', 'ankle', 'lesion extending into depth', 'DFSP']",
"noisy_text": " This one is a nice example of like a cellular DF with lipidization. What part of the body are these most commonly located on? Legs? Yeah, the ankle. In fact, they used to be called the ankle type DF. People still call it that because that's their common location. I don't know why it always occurs in that location, but that's a very common site where you see these. Sometimes they can be several centimeters. If they're really big, they're still benign. Rarely there's been a case of corks and Fletcher who reports everything that can possibly happen that they need to spread to localized nodes. But anyway, this is just a variant of dermatofibromas. I'm glad you guys were able to pick that up. When you see such a big lesion extending that much into the depth, how do you know that this is not a DFSP? Well, it's",
"corrected_text": " This one is a nice example of like a cellular DF with lipidization. What part of the body are these most commonly located on? Legs? Yeah, the ankle. In fact, they used to be called the ankle type DF. People still call it that because that's their common location. I don't know why it always occurs in that location, but that's a very common site where you see these. Sometimes they can be several centimeters. If they're really big, they're still benign. Rarely there's been a case of corks and Fletcher who reports everything that can possibly happen that they need to spread to localized nodes. But anyway, this is just a variant of dermatofibromas. I'm glad you guys were able to pick that up. When you see such a big lesion extending that much into the depth, how do you know that this is not a DFSP? Well, it's",
"med_umls_ids": "[[{'entity': 'Cellular DF', 'concept_id': 'C0007634', 'confidence': 0.7029635906219482}, {'entity': 'lipid accumulation', 'concept_id': 'C0333574', 'confidence': 1.0}, {'entity': 'ankle of legs', 'concept_id': 'C1140621', 'confidence': 0.7117602825164795}, {'entity': 'ankle type DF', 'concept_id': 'C0003086', 'confidence': 0.600553572177887}], [{'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}, {'entity': 'differentiated', 'concept_id': 'C0007589', 'confidence': 1.0}, {'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'depth', 'concept_id': 'C0205125', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_500",
"caption_rating": "7"
},
{
"": "1005738",
"caption": "Uniform cells surrounding the edge of the neurofibroma with rosettes, which may indicate a low-grade fibromyxoid sarcoma.",
"image_path": "QDb68_G1HR4_image_c0024947-4633-4063-90fe-e681cac5115a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " uniform cells that surround the edge of the collagen rosettes when you see those rosettes in this tumor so collagen rosettes in a fibroblastic tumor should be an instant clue that you're probably dealing with a low-grade fibromyxoid sarcoma but do remember again that some variants of schwannoma can also have rosettes and so be sure not to confuse those immunostains can help you out there so I hope that you like this video and that this helps sort this out again make sure that you've checked out my you know five-minute approach to telling apart low-grade fibromyxoid sarcoma from myxofibrosarcoma comma grade 1 and also watch the full-length feature video about myxofibrosarcoma and then I think after seeing this video and those two videos you should have a really solid handle on how to tell these tumors apart I made these videos and went so in-depth because I find that that pathologists often really struggle with these because the name sounds so much alike and in those of us in soft tissue pathology who publish papers maybe we haven't helped the general pathology public so much by making names that all sound so similar. So I hope the video has helped if you liked it please click like down below and leave comments or questions in the comment section and of course make sure you subscribe to my channel if you haven't yet so that you'll be notified about new videos that I post in the future.",
"corrected_text": " uniform cells that surround the edge of the collagen rosettes when you see those rosettes in this tumor so collagen rosettes in a fibroblastic tumor should be an instant clue that you're probably dealing with a low-grade fibromyxoid sarcoma but do remember again that some variants of schwannoma can also have rosettes and so be sure not to confuse those immunostains can help you out there so I hope that you like this video and that this helps sort this out again make sure that you've checked out my you know five-minute approach to telling apart low-grade fibromyxoid sarcoma from myxofibrosarcoma comma grade 1 and also watch the full-length feature video about myxofibrosarcoma and then I think after seeing this video and those two videos you should have a really solid handle on how to tell these tumors apart I made these videos and went so detailed because I find that that pathologists often really struggle with these because the name sounds so much alike and in those of us in soft tissue pathology who publish papers maybe we haven't helped the general pathology public so much by making names that all sound so similar. So I hope the video has helped if you liked it please click like down below and leave comments or questions in the comment section and of course make sure you subscribe to my channel if you haven't yet so that you'll be notified about new videos that I post in the future.",
"med_umls_ids": "[[{'entity': 'Uniform cells', 'concept_id': 'C0007584', 'confidence': 0.6272867321968079}, {'entity': 'edge', 'concept_id': 'C0205154', 'confidence': 1.0}, {'entity': 'neurofibroma', 'concept_id': 'C0027830', 'confidence': 1.0}, {'entity': 'rosettes', 'concept_id': 'C0035863', 'confidence': 0.8847858905792236}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}], [{'entity': 'Immunohistochemistry', 'concept_id': 'C0021044', 'confidence': 0.9999998807907104}, {'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_501",
"caption_rating": "8"
},
{
"": "1004989",
"caption": "CD68 is strongly positive in xanthoma.",
"image_path": "r7OA0Trj5hQ_image_23c31f4f-613e-4a94-8a05-211bd141909a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['young males', 'inflammatory bowel disease', 'lamina propria', 'distinct cell border', 'foamy cytoplasm', 'centrally placed nucleus', 'gastric xanthoma', 'young males', 'inflammatory bowel disease', 'lamina propria', 'distinct cell border', 'foamy cytoplasm', 'centrally placed nucleus', 'gastric xanthoma', 'young males', 'inflammatory bowel disease', 'lamina propria', 'distinct cell border', 'foamy cytoplasm', 'centrally placed nucleus', 'gastric xanthoma']",
"noisy_text": " It is commonly seen in young males, and they present with the signs and symptoms of inflammatory bowel disease. Interesting condition. Here, the lamina propria is full of cells with a distinct cell border, abundant foamy cytoplasm, most of the time centrally placed nucleus. Sometimes it is pushed to the periphery. The central nuclear placement is very important for a diagnosis of xanthoma. For a signet cells, it will be predominantly peripherally pushed nucleus. And when you have doubt, you do a CD68, which will be strongly positive. And so this is a gastric xanthoma. Here, it",
"corrected_text": " It is commonly seen in young males, and they present with the signs and symptoms of inflammatory bowel disease. Interesting condition. Here, the lamina propria is full of cells with a distinct cell border, abundant foamy cytoplasm, most of the time centrally placed nucleus. Sometimes it is pushed to the periphery. The central nuclear placement is very important for a diagnosis of xanthoma. For a signet ring cells, it will be predominantly peripherally pushed nucleus. And when you have doubt, you do a CD68, which will be strongly positive. And so this is a gastric xanthoma. Here, it",
"med_umls_ids": "[[{'entity': 'Xanthoma', 'concept_id': 'C0302314', 'confidence': 1.0}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'young', 'concept_id': 'C0332239', 'confidence': 1.0}, {'entity': 'males', 'concept_id': 'C0086582', 'confidence': 1.0}, {'entity': 'signs', 'concept_id': 'C0220912', 'confidence': 0.9999999403953552}, {'entity': 'symptoms', 'concept_id': 'C0683368', 'confidence': 1.0}, {'entity': 'inflammatory bowel disease', 'concept_id': 'C0021390', 'confidence': 1.0}], [{'entity': 'Lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'cell border', 'concept_id': 'C0205284', 'confidence': 0.773768424987793}, {'entity': 'foamy cytoplasm', 'concept_id': 'C0010834', 'confidence': 0.7207725048065186}, {'entity': 'centrally', 'concept_id': 'C0205099', 'confidence': 0.7070305943489075}, {'entity': 'nucleus', 'concept_id': 'C0007610', 'confidence': 1.0}, {'entity': 'gastric xanthoma', 'concept_id': 'C1282522', 'confidence': 1.0}], [{'entity': 'CD68', 'concept_id': 'C0108799', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'xanthoma', 'concept_id': 'C0302314', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_502",
"caption_rating": "8"
},
{
"": "1006261",
"caption": "The biopsy shows a busy appearance with few benign glands and some cribriform glands.",
"image_path": "iklRyY1nBIE_image_e14ab13a-e981-42a6-8f7b-157c3d113a12.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['p63-positive prostate cancer', 'digital rectal examination', 'PSA levels', 'busy appearance', 'cribriform glands', 'p63-positive prostate cancer', 'digital rectal examination', 'PSA levels', 'busy appearance', 'cribriform glands']",
"noisy_text": " So this is another example of P63-positive prostate cancer. As you come over here, you can see it's the same process going on. Some of these glands look like conventional prostate cancer. This one looks like it's kind of undecided whether it should be P63-positive or conventional prostate cancer. As you come over here, this one looks like conventional prostate cancer. And then you have some others that are staining with P63. So this is another example of P63-positive prostate cancer. It's somewhat controversial whether to assign a glycine score to these. Obviously, if they form, if they have well-formed glands, that would be equivalent to glycine score 3 plus 3 equals 6 grade group 1. But the question is, the original case I showed you, when you have those polyform glands or single cells, it becomes debatable whether to assign a high glycine score to those cases. Because as of now, most of these tumors are relatively well-behaved. So that's still an area that is unsolved. So this was just a very good example of P63-positive prostate cancer. We'll move on to case 3. Case 3 is a 73-year-old man who presented with a positive digital rectal examination and elevated PSA levels. Again, you can see that a lot of the histories are beginning to overlap now. They look very similar. In this particular case, we have a different process going on. It's very busy. You can see there are a lot of glands, very, very busy. Very few benign glands there. There's some colonic tissue there. And as you keep looking at the core, you can see that there are some cribriform glands present. These glands,",
"corrected_text": " So this is another example of p63-positive prostate cancer. As you come over here, you can see it's the same process going on. Some of these glands look like conventional prostate cancer. This one looks like it's kind of undecided whether it should be p63-positive or conventional prostate cancer. As you come over here, this one looks like conventional prostate cancer. And then you have some others that are staining with P63. So this is another example of p63-positive prostate cancer. It's somewhat controversial whether to assign a glycine score to these. Obviously, if they form, if they have well-formed glands, that would be equivalent to glycine score 3 plus 3 equals 6 grade group 1. But the question is, the original case I showed you, when you have those polyform glands or single cells, it becomes debatable whether to assign a high glycine score to those cases. Because as of now, most of these tumors are relatively well-behaved. So that's still an area that is unsolved. So this was just a very good example of p63-positive prostate cancer. We'll move on to case 3. Case 3 is a 73-year-old man who presented with a positive digital rectal examination and elevated PSA levels. Again, you can see that a lot of the histories are beginning to overlap now. They look very similar. In this particular case, we have a different process going on. It's very busy. You can see there are a lot of glands, very, very busy. Very few benign glands there. There's some colonic tissue there. And as you keep looking at the core, you can see that there are some cribriform glands present. These glands,",
"med_umls_ids": "[[{'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'p63-positive', 'concept_id': 'C4329511', 'confidence': 0.5139493942260742}, {'entity': 'prostate cancer', 'concept_id': 'C0376358', 'confidence': 1.0}], [{'entity': 'glycine', 'concept_id': 'C0017890', 'confidence': 1.0}, {'entity': 'score', 'concept_id': 'C0449820', 'confidence': 1.0}, {'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}], [{'entity': 'Case 3', 'concept_id': 'C0868928', 'confidence': 0.8432309031486511}, {'entity': 'man', 'concept_id': 'C0025266', 'confidence': 1.0}, {'entity': 'positive digital rectal examination', 'concept_id': 'C0199900', 'confidence': 0.8765994906425476}, {'entity': 'elevated', 'concept_id': 'C0205250', 'confidence': 0.9999999403953552}, {'entity': 'PSA', 'concept_id': 'C0138741', 'confidence': 1.0}, {'entity': 'levels', 'concept_id': 'C0441889', 'confidence': 1.0}], [{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'benign glands', 'concept_id': 'C1301287', 'confidence': 0.726940393447876}, {'entity': 'cribriform glands', 'concept_id': 'C1285092', 'confidence': 0.6162902116775513}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_503",
"caption_rating": "7"
},
{
"": "1006836",
"caption": "Surface epithelium showing goblet cells.",
"image_path": "r7OA0Trj5hQ_image_106ad5eb-cc4c-4670-b26e-1ee0397de984.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Neutrophils on the epithelium indicating active inflammation', 'H. pylori in the luminal area or lumen', 'Goblet cells in the surface epithelium.', 'H. pylori in the luminal area or lumen']",
"noisy_text": " this is equivalent to cryptitis in the colon. In the stomach, we call it pit, so I don't want to call it pititis. It doesn't sound very great, but you can see the neutrophils sitting on the epithelium. So this is an active inflammation. Here, now we are coming to cytology. You see in the intra-luminal area or in the lumen, you see a lot of comma-shaped rods sitting on the epithelium, not going into the epithelium. So these are all the H. pylori in the oil immersion. Here, the surface epithelium shows goblet cells, and these are all biopsies",
"corrected_text": " this is equivalent to cryptitis in the colon. In the stomach, we call it pit, so I don't want to call it pititis. It doesn't sound very great, but you can see the neutrophils sitting on the epithelium. So this is an active inflammation. Here, now we are coming to cytology. You see in the luminal area or in the lumen, you see a lot of comma-shaped rods sitting on the epithelium, not going into the epithelium. So these are all the H. pylori in the oil immersion. Here, the surface epithelium shows goblet cells, and these are all biopsies",
"med_umls_ids": "[[{'entity': 'Active inflammation', 'concept_id': 'C0333361', 'confidence': 1.0}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'H. pylori', 'concept_id': 'C0079488', 'confidence': 1.0}, {'entity': 'luminal area', 'concept_id': 'C0524462', 'confidence': 0.7778207659721375}, {'entity': 'lumen', 'concept_id': 'C0524461', 'confidence': 0.9999998807907104}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}], [{'entity': 'Surface epithelium', 'concept_id': 'C1182809', 'confidence': 1.0}, {'entity': 'goblet cells', 'concept_id': 'C0506994', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_504",
"caption_rating": "8"
},
{
"": "1004198",
"caption": "The presence of a diffuse pattern between and among lipocytes is characteristic of DFSP.",
"image_path": "LlPaENuqzVQ_image_76a5b714-55f4-4548-a00f-fcd28a02bf2a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['diffuse pattern between and among lipocytes', 'typical storiform pattern', 'ring chromosome', 'translocation involving collagen A and platelet-derived growth factor', 'diffuse pattern between and among lipocytes']",
"noisy_text": " you can impress your friends and colleagues. You can say, this is DFSB. You don't need the storiform pattern. If you see this, you got the diagnosis. No other neoplasm really gets diffusely between and among lipocytes in a diffuse pattern like this, other than DFSB. Now you look up here and yeah, you do have the nice, beautiful storiform pattern here. And you don't really need a CD34 stain here. You can do it if you want to, if you like to sort of charge patients extra money, but this is a classic DFSB. And that ring chromosome, the collagen A, platelet-derived growth factor, the translocation is classic for that. And one",
"corrected_text": " you can impress your friends and colleagues. You can say, this is DFSP. You don't need the storiform pattern. If you see this, you got the diagnosis. No other neoplasm really gets diffusely between and among lipocytes in a diffuse pattern like this, other than DFSP. Now you look up here and yeah, you do have the nice, typical storiform pattern here. And you don't really need a CD34 stain here. You can do it if you want to, if you like to sort of charge patients extra money, but this is a classic DFSP. And that ring chromosome, the collagen A, platelet-derived growth factor, the translocation is classic for that. And one",
"med_umls_ids": "[[{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'diffuse', 'concept_id': 'C0205219', 'confidence': 1.0}, {'entity': 'lipocytes', 'concept_id': 'C0206131', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}], [{'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}, {'entity': 'storiform pattern', 'concept_id': 'C1336510', 'confidence': 0.8142904043197632}], [{'entity': 'CD34 stain', 'concept_id': 'C0038128', 'confidence': 0.5134490728378296}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'ring chromosome', 'concept_id': 'C0035639', 'confidence': 1.0}, {'entity': 'translocation', 'concept_id': 'C0040715', 'confidence': 1.0}, {'entity': 'collagen A', 'concept_id': 'C0009325', 'confidence': 0.9128584265708923}, {'entity': 'platelet-derived growth factor', 'concept_id': 'C0032200', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_505",
"caption_rating": "8"
},
{
"": "1005558",
"caption": "The presence of a diffuse pattern between and among lipocytes is characteristic of DFSP.",
"image_path": "LlPaENuqzVQ_image_98c4a67e-3d00-4305-a909-bf584c2ec7a5.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['diffuse pattern between and among lipocytes', 'diffuse pattern between and among lipocytes', 'typical storiform pattern', 'ring chromosome', 'translocation involving collagen A and platelet-derived growth factor']",
"noisy_text": " you can impress your friends and colleagues. You can say, this is DFSB. You don't need the storiform pattern. If you see this, you got the diagnosis. No other neoplasm really gets diffusely between and among lipocytes in a diffuse pattern like this, other than DFSB. Now you look up here and yeah, you do have the nice, beautiful storiform pattern here. And you don't really need a CD34 stain here. You can do it if you want to, if you like to sort of charge patients extra money, but this is a classic DFSB. And that ring chromosome, the collagen A, platelet-derived growth factor, the translocation is classic for that. And one",
"corrected_text": " you can impress your friends and colleagues. You can say, this is DFSP. You don't need the storiform pattern. If you see this, you got the diagnosis. No other neoplasm really gets diffusely between and among lipocytes in a diffuse pattern like this, other than DFSP. Now you look up here and yeah, you do have the nice, typical storiform pattern here. And you don't really need a CD34 stain here. You can do it if you want to, if you like to sort of charge patients extra money, but this is a classic DFSP. And that ring chromosome, the collagen A, platelet-derived growth factor, the translocation is classic for that. And one",
"med_umls_ids": "[[{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'diffuse', 'concept_id': 'C0205219', 'confidence': 1.0}, {'entity': 'lipocytes', 'concept_id': 'C0206131', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}], [{'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}, {'entity': 'storiform pattern', 'concept_id': 'C1336510', 'confidence': 0.8142904043197632}], [{'entity': 'CD34 stain', 'concept_id': 'C0038128', 'confidence': 0.5134490728378296}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'ring chromosome', 'concept_id': 'C0035639', 'confidence': 1.0}, {'entity': 'translocation', 'concept_id': 'C0040715', 'confidence': 1.0}, {'entity': 'collagen A', 'concept_id': 'C0009325', 'confidence': 0.9128584265708923}, {'entity': 'platelet-derived growth factor', 'concept_id': 'C0032200', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_506",
"caption_rating": "8"
},
{
"": "1007932",
"caption": "Follicular lymphoma is strongly positive for CD20 and BCL6 in the follicle areas.",
"image_path": "udoW6VSqsm4_image_87e1a3ac-6bb3-4783-b988-5b839a4aa76c.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['Follicular lymphoma', 'CD20', 'BCL6', 'follicle arrangement', 'Follicular lymphoma', 'CD20', 'BCL6', 'follicle arrangement']",
"noisy_text": " and they often respond, you know, just an interracial steroid, local radiotherapy, some sort of excision. So, you know, this was follicle center cell lymphoma. There's one type that's comprised mostly of small lymphocytes, there's other types comprised mostly of the follicle cells. So there's the fuse, and then there's a follicular, there's kind of a mixed pattern. You don't need to know as much about this, but the way we work these up, they're strongly positive for CD20, and they're BCL6 positive in those follicle areas. And I like that kind of inside out follicle kind of arrangement. I think there's a photograph that kind of shows that. So these are the two different patterns, the follicular and the fuse, and then you can see the surrounding large neoplastic cells with the smaller lymphocytes. It's kind",
"corrected_text": " and they often respond, you know, just an interracial steroid, local radiotherapy, some sort of excision. So, you know, this was Follicular lymphoma. There's one type that's comprised mostly of small lymphocytes, there's other types comprised mostly of the follicle cells. So there's the fuse, and then there's a follicular, there's kind of a mixed pattern. You don't need to know as much about this, but the way we work these up, they're strongly positive for CD20, and they're BCL6 positive in those follicle areas. And I like that kind of inside out follicle kind of arrangement. I think there's a photograph that kind of shows that. So these are the two different patterns, the follicular and the fuse, and then you can see the surrounding large neoplastic cells with the smaller lymphocytes. It's kind",
"med_umls_ids": "[[{'entity': 'Follicular lymphoma', 'concept_id': 'C0024301', 'confidence': 1.0}, {'entity': 'treated with', 'concept_id': 'C0332293', 'confidence': 1.0}, {'entity': 'interracial', 'concept_id': 'C0682081', 'confidence': 0.9999999403953552}, {'entity': 'steroid', 'concept_id': 'C0038317', 'confidence': 1.0}, {'entity': 'local radiotherapy', 'concept_id': 'C0034619', 'confidence': 0.8772267699241638}, {'entity': 'excision', 'concept_id': 'C0015252', 'confidence': 1.0}], [{'entity': 'Follicular lymphoma', 'concept_id': 'C0024301', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'CD20', 'concept_id': 'C1417326', 'confidence': 1.0}, {'entity': 'BCL6', 'concept_id': 'C1332399', 'confidence': 1.0}, {'entity': 'follicle', 'concept_id': 'C0018120', 'confidence': 1.0}, {'entity': 'areas', 'concept_id': 'C0205146', 'confidence': 1.0}], [{'entity': 'Follicular lymphoma', 'concept_id': 'C0024301', 'confidence': 1.0}, {'entity': 'patterns', 'concept_id': 'C0449774', 'confidence': 1.0}, {'entity': 'follicular', 'concept_id': 'C0439682', 'confidence': 1.0}, {'entity': 'diffuse', 'concept_id': 'C0205219', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_507",
"caption_rating": "9"
},
{
"": "1005958",
"caption": "Example of an intravascular metastatic breast cancer.",
"image_path": "LlPaENuqzVQ_image_7b28124b-26e5-41df-a292-b4158529706a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['Atypical cells inside blood vessels with hyperchromatic nuclei.', 'Large cells hugging each other and looking epithelial.']",
"noisy_text": " So the inflammation is probably happening secondary to that. This is, whoa, these cells don't belong here. And, you know, they're sitting inside these blood vessels and they look atypical. There's like hyperchromatic nuclei here. They vary in size and shape. Like intravascular, it doesn't, like lymphoma? I mean, the only thing I think of where it's like, you don't have a huge inflammatory response like intravascular lymphoma. Yeah, yeah. So you say the intravascular neoplasm of some sort. Well, I'm not sure what this is. And they kind of look epithelial. If you look at it, it looks like these cells are really hugging one another and they're pretty large. So yeah, I would agree with you. I'd say this is an intravascular neoplasm and maybe it's a metastatic neoplasm to the skin that's possibly epithelial. If it's a lymphoma, it's going to be pretty weird. It'd have to be some kind of a histiocytoid lymphoma, something that's got these cells very large and looks like histiocytes. This is an example of an intravascular metastatic breast cancer in this case. And probably the lymphocytic infiltrator is just, you know, it's like",
"corrected_text": " So the inflammation is probably happening secondary to that. This is, whoa, these cells don't belong here. And, you know, they're sitting inside these blood vessels and they look atypical. There's like hyperchromatic nuclei here. They vary in size and shape. Like intravascular, it doesn't, like lymphoma? I mean, the only thing I think of where it's like, you don't have a huge inflammatory response like intravascular lymphoma. Yeah, yeah. So you say the intravascular neoplasm of some sort. Well, I'm not sure what this is. And they kind of look epithelial. If you look at it, it looks like these cells are really hugging one another and they're pretty large. So yeah, I would agree with you. I'd say this is an intravascular neoplasm and maybe it's a metastatic neoplasm to the skin that's possibly epithelial. If it's a lymphoma, it's going to be pretty weird. It'd have to be some kind of a histiocytic lymphoma, something that's got these cells very large and looks like histiocytes. This is an example of an intravascular metastatic breast cancer in this case. And probably the lymphocytic infiltrator is just, you know, it's like",
"med_umls_ids": "[[{'entity': 'Inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}, {'entity': 'secondary', 'concept_id': 'C0027627', 'confidence': 1.0}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'atypical cells', 'concept_id': 'C0333865', 'confidence': 1.0}, {'entity': 'blood vessels', 'concept_id': 'C0005847', 'confidence': 1.0}], [{'entity': 'Hyperchromatic nuclei', 'concept_id': 'C3553776', 'confidence': 1.0}, {'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'shape', 'concept_id': 'C0332479', 'confidence': 1.0}], [{'entity': 'Intravascular neoplasm', 'concept_id': 'C0027668', 'confidence': 0.8177628517150879}, {'entity': 'suspected', 'concept_id': 'C0332147', 'confidence': 1.0}, {'entity': 'metastatic neoplasm', 'concept_id': 'C0027627', 'confidence': 0.9999999403953552}, {'entity': 'skin', 'concept_id': 'C0444099', 'confidence': 1.0}, {'entity': 'epithelial', 'concept_id': 'C0221908', 'confidence': 1.0}, {'entity': 'nature', 'concept_id': 'C0349590', 'confidence': 1.0}], [{'entity': 'lymphoma', 'concept_id': 'C0024299', 'confidence': 1.0}, {'entity': 'histiocytic lymphoma', 'concept_id': 'C0024302', 'confidence': 1.0}, {'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}], [{'entity': 'intravascular metastatic breast cancer', 'concept_id': 'C0278488', 'confidence': 0.766404926776886}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_508",
"caption_rating": "8"
},
{
"": "1009108",
"caption": "Histopathological description of a tumor with big collagen rich rosettes and a prominent round cell appearance around the edge of the rim of the nodules, resembling small round blue cells of a neuroblastoma.",
"image_path": "QDb68_G1HR4_image_85c0ccc4-360e-44bc-84d0-3c033ab285e7.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Big collagen rich rosettes', 'Prominent round cell appearance around the edge of the rim of the nodules', 'Small round blue cells of a neuroblastoma']",
"noisy_text": " It has also big collagen rich rosettes like this but it has a much more prominent round cell appearance around the edge of the rim of the nodules are very like small round blue cell almost look a little bit like the small round blue cells of a neuroblastoma which is why it's named that way but I've definitely seen pathologists have trouble telling those two apart telling a hyalinizing spindle cell tumor with giant rosettes. This tumor we're looking at here a variation of low-grade fibromyxoid sarcoma I've seen people get that confused with the neuroblastoma-like variant of schwannoma and the difference is important because the schwannoma is even though the name sounds kind of scary is actually benign it has a small round blue cell appearance but it's totally benign variation of schwannoma. S100 should easily solve that problem because S100 would be negative here in low-grade fibromyxoid sarcoma and",
"corrected_text": " It has also big collagen rich rosettes like this but it has a much more prominent round cell appearance around the edge of the rim of the nodules are very like small round blue cell almost look a little bit like the small round blue cells of a neuroblastoma which is why it's named that way but I've definitely seen pathologists have trouble telling those two apart telling a hyalinizing spindle cell tumor with giant rosettes. This tumor we're looking at here a variation of low-grade fibromyxoid sarcoma I've seen people get that confused with the neuroblastoma-like variant of schwannoma and the difference is important because the schwannoma is even though the name sounds kind of scary is actually benign it has a small round blue cell appearance but it's totally benign variation of schwannoma. S100 should easily solve that problem because S100 would be negative here in low-grade fibromyxoid sarcoma and",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'rosettes', 'concept_id': 'C0035863', 'confidence': 0.8847858905792236}, {'entity': 'round cell', 'concept_id': 'C0487470', 'confidence': 1.0}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'edge', 'concept_id': 'C0205154', 'confidence': 1.0}, {'entity': 'rim', 'concept_id': 'C1308727', 'confidence': 1.0}, {'entity': 'nodules', 'concept_id': 'C0028259', 'confidence': 1.0}, {'entity': 'neuroblastoma', 'concept_id': 'C0027819', 'confidence': 1.0}], [{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'variation', 'concept_id': 'C0205419', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'neuroblastoma-like variant of', 'concept_id': 'C1419295', 'confidence': 0.6589864492416382}, {'entity': 'schwannoma', 'concept_id': 'C0027809', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_509",
"caption_rating": "9"
},
{
"": "1006881",
"caption": "Zonation of more and less cellular areas of pink fibrous can be helpful in diagnosis.",
"image_path": "QDb68_G1HR4_image_2d07ce43-7c97-4d79-8e95-3a4f9f1d4f2a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " There have also been rare reports of cases that truly have a full-blown high-grade pleomorphic sarcoma like appearance like that they've transitioned into high-grade sarcoma or I think even osteosarcomatous areas have been described. These are all really rare exceptions to the rule but I and I think it's again much more important for the general pathologists to know that this very bland benign looking appearance because this is the one that's going to be easy to misdiagnose and diagnose it as something benign when it's actually malignant. So again here look at the alternation more cellular stuff less cellular stuff very helpful to see this kind of zonation in swirling intermingling of more and less cellular areas of pink fibrous areas and",
"corrected_text": " There have also been rare reports of cases that truly have a full-blown high-grade pleomorphic sarcoma like appearance like that they've transitioned into high-grade sarcoma or I think even osteosarcomatous areas have been described have been described. These are all really rare exceptions to the rule but I and I think it's again much more important for the general pathologists to know that this very bland benign looking appearance because this is the one that's going to be easy to misdiagnose and diagnose it as something benign when it's actually malignant. So again here look at the alternation more cellular stuff less cellular stuff very helpful to see this kind of zonation in swirling intermingling of more and less cellular areas of pink fibrous areas and",
"med_umls_ids": "[[{'entity': 'Rare', 'concept_id': 'C0521114', 'confidence': 1.0}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'cysts', 'concept_id': 'C0010709', 'confidence': 1.0}, {'entity': 'high-grade', 'concept_id': 'C1512433', 'confidence': 0.9347730875015259}, {'entity': 'pleomorphic sarcoma', 'concept_id': 'C1261358', 'confidence': 0.9260651469230652}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'osteosarcomatous areas', 'concept_id': 'C0279602', 'confidence': 0.7822340130805969}], [{'entity': 'pathologists', 'concept_id': 'C0334866', 'confidence': 1.0}, {'entity': 'benign', 'concept_id': 'C0205183', 'confidence': 1.0}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'cysts', 'concept_id': 'C0010709', 'confidence': 1.0}, {'entity': 'misdiagnosed', 'concept_id': 'C0679838', 'confidence': 0.896425724029541}, {'entity': 'malignant', 'concept_id': 'C0205282', 'confidence': 1.0}], [{'entity': 'Zonation', 'concept_id': 'C0019360', 'confidence': 0.7375882267951965}, {'entity': 'cellular areas', 'concept_id': 'C0007634', 'confidence': 0.7882957458496094}, {'entity': 'pink fibrous', 'concept_id': 'C0439709', 'confidence': 0.7378140091896057}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_510",
"caption_rating": "7"
},
{
"": "1008955",
"caption": "Glut-1 is usually negative in perineuriomas, but there are rare reports of positive staining in low-grade fibromyxoid sarcomas.",
"image_path": "QDb68_G1HR4_image_aeb1e9b8-0fa5-431a-89b7-ff906dab1235.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Deep soft tissue', 'Perineurioma', 'Low-grade fibromyxoid sarcoma', 'Immunohistochemistry', 'Swirling growth']",
"noisy_text": " involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is more of a difficult problem because perineurioma has a lot of overlap histologically with low-grade fibromyxoid sarcoma and also immunohistochemically. On immunostains, EMA, Clodin-1 and Glut-1 are three immunostains that will usually stain perineuriomas. The problem is that low-grade fibromyxoid sarcomas often express at least focal EMA, so that's a problem and additionally, the examples of low-grade fibromyxoid sarcoma that have dramatic swirling and whirling growth, those are the ones that have a perineurioma like pattern, the ones that mimic perineurioma. They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The",
"corrected_text": " involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is more of a difficult problem because perineurioma has a lot of overlap histologically with low-grade fibromyxoid sarcoma and also immunohistochemically. On immunostains, EMA, Clodin-1 and Glut-1 are three immunostains that will usually stain perineuriomas. The problem is that low-grade fibromyxoid sarcomas often express at least focal EMA, so that's a problem and additionally, the examples of low-grade fibromyxoid sarcoma that have dramatic swirling and whirling growth, those are the ones that have a perineurioma like pattern, the ones that mimic perineurioma. They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The",
"med_umls_ids": "[[{'entity': 'CD34', 'concept_id': 'C0054953', 'confidence': 1.0}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'deep soft tissue tumors', 'concept_id': 'C0037579', 'confidence': 0.8622524738311768}], [{'entity': 'Perineurioma', 'concept_id': 'C0751691', 'confidence': 0.9999999403953552}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'histologically', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'immunohistochemistry', 'concept_id': 'C0021044', 'confidence': 0.9999998807907104}], [{'entity': 'EMA', 'concept_id': 'C0268596', 'confidence': 0.9999999403953552}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}, {'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'immunohistochemical stains', 'concept_id': 'C4317108', 'confidence': 0.9999999403953552}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibrosarcomas', 'concept_id': 'C0016057', 'confidence': 1.0}, {'entity': 'EMA', 'concept_id': 'C0268596', 'confidence': 0.9999999403953552}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}], [{'entity': 'Low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'swirling', 'concept_id': 'C0233591', 'confidence': 0.7064549922943115}, {'entity': 'growth', 'concept_id': 'C0018270', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'express', 'concept_id': 'C0017262', 'confidence': 0.8176293969154358}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}], [{'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'reports', 'concept_id': 'C0684224', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcomas', 'concept_id': 'C1275282', 'confidence': 0.8123146891593933}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_511",
"caption_rating": "8"
},
{
"": "1004622",
"caption": "Enlarged nuclei that are about six times the size of normal prostate nuclei.",
"image_path": "iklRyY1nBIE_image_25cf08c9-c9d9-4441-a9ec-9d3954d4c095.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['basal cells at the periphery', 'enlarged nuclei', 'intraductal carcinoma of the prostate', 'adjacent invasive tumor', 'previously benign gland', 'basal cells at the periphery', 'enlarged nuclei', 'intraductal carcinoma of the prostate', 'adjacent invasive tumor', 'previously benign gland']",
"noisy_text": " Let me show you what the cocktail looks like. Again, this is the pin three, or some call it pin four. You have the P63, you have the hemoglobin cytokeratin, and then you have the racemase, which is the pink chromogen. And as you can see, as I demonstrated on the H&E, basal cells are indeed present. This is too much for high-grade pin. This is basically what is called a solid cribriform kind of pattern, in which over 50% of the lumen is filled by tumor cells. So this is way too much for high-grade pin. But it's not invasive, because you have basal cells at the periphery. And the nuclei are enlarged. These nuclei are about six times the size of normal prostate nuclei. So this case meets the criteria for introductal carcinoma of the prostate. There is an invasive component, which you can see is negative for basal cell markers. But you have the introductal component. And this is a very interesting entity. The vast majority of cases, and I'll show you the corresponding radical prostatectomy specimens in a second, but the vast majority of these so-called introductal carcinoma of the prostate is due to invasion, colonization by adjacent invasive tumor. And it usually occurs in patients that have high-volume tumors. When I show you the corresponding radical prostatectomies, you'll see what I'm talking about. You usually don't have this in patients in their radicals that have 5% prostate cancer or 10% prostate cancer. It's usually patients that have extensive prostate cancer involvement, and the invasive glands basically have nowhere else to go but to colonize adjacent benign glands. And I'll demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues,",
"corrected_text": " Let me show you what the cocktail looks like. Again, this is the pin three, or some call it pin four. You have the P63, you have the hemoglobin cytokeratin, and then you have the racemase, which is the AMACR. And as you can see, as I demonstrated on the H&E, basal cells are indeed present. This is too much for high-grade pin. This is basically what is called a solid cribriform kind of pattern, in which over 50% of the lumen is filled by tumor cells. So this is way too much for high-grade pin. But it's not invasive, because you have basal cells at the periphery. And the nuclei are enlarged. These nuclei are about six times the size of normal prostate nuclei. So this case meets the criteria for intraductal carcinoma of the prostate. There is an invasive component, which you can see is negative for basal cell markers. But you have the intraductal component. And this is a very interesting entity. The vast majority of cases, and I'll show you the corresponding radical prostatectomy specimens in a second, but the vast majority of these so-called intraductal carcinoma of the prostate is due to invasion, colonization by adjacent invasive tumor. And it usually occurs in patients that have high-volume tumors. When I show you the corresponding radical prostatectomies, you'll see what I'm talking about. You usually don't have this in patients in their radicals that have 5% prostate cancer or 10% prostate cancer. It's usually patients that have extensive prostate cancer involvement, and the invasive glands basically have nowhere else to go but to colonize adjacent benign glands. And I'demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues,",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'cocktail', 'concept_id': 'C0678420', 'confidence': 1.0}, {'entity': 'markers', 'concept_id': 'C0181734', 'confidence': 0.890313982963562}, {'entity': 'intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate diagnosis', 'concept_id': 'C0011900', 'confidence': 0.7927443981170654}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'basal cells', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}], [{'entity': 'Enlarged nuclei', 'concept_id': 'C4013177', 'confidence': 0.7774685621261597}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'normal', 'concept_id': 'C0205307', 'confidence': 1.0}], [{'entity': 'Intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'invasion', 'concept_id': 'C1269955', 'confidence': 1.0}, {'entity': 'colonization', 'concept_id': 'C4289767', 'confidence': 1.0}, {'entity': 'adjacent', 'concept_id': 'C0205117', 'confidence': 1.0}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}], [{'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'benign gland', 'concept_id': 'C0205183', 'confidence': 0.7986565828323364}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_512",
"caption_rating": "8"
},
{
"": "1006597",
"caption": "Description of atrophic features in glands with some changes in interluminal mucin and pink secretions.",
"image_path": "iklRyY1nBIE_image_05dba902-598b-4a20-8adc-2854635c352e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['atrophic features', 'interluminal mucin and pink secretions', 'cytoplasmic features']",
"noisy_text": " But let's go closer still and see what's going on. So as you look at some of these glands, again, you can appreciate that they have atrophic features. The nuclei are spaced apart a little bit. And this one actually has a little change of interluminal mucin and pink secretions. But from the histologic standpoint, they don't look that atypical. They don't have, you know, some of them have a little bit of pinpoint nucleoli, but they don't look that worrisome. The only issue is that some of these glands look like they're beginning to infiltrate a little bit. And that's what caused concern with the outside pathology. So some of them actually thought this was cancer because you have these bigger glands that look benign, and then you have this second population of smaller glands that appear like they're infiltrating. So of course, they went ahead and did, even as the chemical stains, which I'll share with you shortly. But I want you to just kind of burn this in your mind for a second, because when I show you the stains, it's going to be important for you to correlate what you're seeing now with the stains. So one other thing I want to draw your attention to before we look at the pink cocktail is that the cytoplasmic features of these smaller glands and even the larger benign glands next door are somewhat similar. So that's going to become very important when I show you these things. So we'll go ahead and look at the corresponding pink cocktail on that case. And this",
"corrected_text": " But let's go closer still and see what's going on. So as you look at some of these glands, again, you can appreciate that they have atrophic features. The nuclei are spaced apart a little bit. And this one actually has a little change in interluminal mucin and pink secretions. But from the histologic standpoint, they don't look that atypical. They don't have, you know, some of them have a little bit of pinpoint nucleoli, but they don't look that worrisome. The only issue is that some of these glands look like they're beginning to infiltrate a little bit. And that's what caused concern with the outside pathology. So some of them actually thought this was cancer because you have these bigger glands that look benign, and then you have this second population of smaller glands that appear like they're infiltrating. So of course, they went ahead and did, even as the chemical stains, which I'share with you shortly. But I want you to just kind of burn this in your mind for a second, because when I show you the stains, it's going to be important for you to correlate what you're seeing now with the stains. So one other thing I want to draw your attention to before we look at the pink cocktail is that the cytoplasmic features of these smaller glands and even the larger benign glands next door are somewhat similar. So that's going to become very important when I show you these things. So we'll go ahead and look at the corresponding pink cocktail on that case. And this",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'atrophic', 'concept_id': 'C0151514', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'changes', 'concept_id': 'C0392747', 'confidence': 1.0}, {'entity': 'interluminal mucin', 'concept_id': 'C0911725', 'confidence': 0.6244790554046631}, {'entity': 'pink secretions', 'concept_id': 'C0036537', 'confidence': 0.7841725945472717}], [{'entity': 'Concerns', 'concept_id': 'C2699424', 'confidence': 1.0}, {'entity': 'infiltration', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'suspicion', 'concept_id': 'C0242114', 'confidence': 1.0}], [{'entity': 'Importance', 'concept_id': 'C4086513', 'confidence': 0.96006178855896}, {'entity': 'correlating', 'concept_id': 'C1707520', 'confidence': 0.8486447334289551}, {'entity': 'histologic', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'chemical stains', 'concept_id': 'C0220806', 'confidence': 0.731187641620636}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_513",
"caption_rating": "8"
},
{
"": "1007654",
"caption": "The biopsy is taken from the body of the stomach, where peritoneal cells, mucincycletine cells, and chief cells are present.",
"image_path": "r7OA0Trj5hQ_image_753d9b8c-367b-4d02-9609-187d48ccfe78.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Goblet cells in gastric mucosa', 'Peritoneal cells in the body of the stomach']",
"noisy_text": " So the best stain for H. pylori is careful examination of H&E. Here H&E picture showing goblet cells in a gastric mucosa. The goblet cells are taking blue color, in algean blue, whereas the gastric epithelium is taking the PAS color. So this is algean blue PAS, intersternal metaplasia of the gastric mucosa. Here the history is this biopsy is taken from the body of the stomach. In the body of the stomach, you have to see a lot of fried eggs. These are all the peritoneal cells in addition to mucincycletine cells and chief cells. These are the peritoneal cells. When you",
"corrected_text": " So the best stain for H. pylori is careful examination of H&E. Here H&E picture showing goblet cells in a gastric mucosa. The goblet cells are taking blue color, in Alcian blue, whereas the gastric epithelium is taking the PAS color. So this is Alcian blue PAS, intestinal metaplasia of the gastric mucosa. Here the history is this biopsy is taken from the body of the stomach. In the body of the stomach, you have to see a lot of fried eggs. These are all the peritoneal cells in addition to mucincycletine cells and chief cells. These are the peritoneal cells. When you",
"med_umls_ids": "[[{'entity': 'H. pylori', 'concept_id': 'C0079488', 'confidence': 1.0}, {'entity': 'visualized', 'concept_id': 'C0234621', 'confidence': 1.0}, {'entity': 'examination', 'concept_id': 'C0031809', 'confidence': 1.0}, {'entity': 'H&E stain', 'concept_id': 'C0523207', 'confidence': 1.0}], [{'entity': 'image', 'concept_id': 'C1696103', 'confidence': 1.0}, {'entity': 'goblet cells', 'concept_id': 'C0506994', 'confidence': 0.9999999403953552}, {'entity': 'gastric mucosa', 'concept_id': 'C0017136', 'confidence': 1.0}, {'entity': 'blue color', 'concept_id': 'C1260957', 'confidence': 1.0}, {'entity': 'Alcian blue', 'concept_id': 'C0001933', 'confidence': 1.0}, {'entity': 'PAS', 'concept_id': 'C0030125', 'confidence': 1.0}, {'entity': 'color', 'concept_id': 'C0009393', 'confidence': 1.0}, {'entity': 'gastric epithelium', 'concept_id': 'C0227208', 'confidence': 1.0}], [{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'body', 'concept_id': 'C0227230', 'confidence': 1.0}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'peritoneal cells', 'concept_id': 'C0031153', 'confidence': 0.7749612331390381}, {'entity': 'mucincycletine cells', 'concept_id': 'C0007586', 'confidence': 0.6177586317062378}, {'entity': 'chief cells', 'concept_id': 'C1516470', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_514",
"caption_rating": "7"
},
{
"": "1004488",
"caption": "Localized abnormalities in the epithelium can occur due to somatic mutations, such as in poro and clear cell acanthoma.",
"image_path": "udoW6VSqsm4_image_73ee6627-c4ef-4043-864e-d1bd58954a72.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['abnormalities in localized areas of the epithelium', 'clear staining glycogenated keratinocytes', 'basal cell-like appearance of clear cell acanthoma.']",
"noisy_text": " And there's one other condition where you kind of get, where are some other little clonal, you know, somatic mutations that you can get abnormalities in the epithelium that occur just in localized areas. That's not like loss of the coronified layer. We'll put a couple of other diseases where you see just local areas that are abnormal, and you get normal skin to the side. So, poro is one. We'll put a couple of others. So, it looked like psoriasis, and it had a lot of clear staining glycogenated keratinocytes. It was just one little localized packet. It looked like a basal cell. Yeah, clear cellular acanthoma. What if",
"corrected_text": " And there's one other condition where you kind of get, where are some other little clonal, you know, somatic mutations that you can get abnormalities in the epithelium that occur just in localized areas. That's not like loss of the cornified layer. We'll put a couple of other diseases where you see just local areas that are abnormal, and you get normal skin to the side. So, poro is one. We'll put a couple of others. So, it looked like psoriasis, and it had a lot of clear staining glycogenated keratinocytes. It was just one little localized packet. It looked like a basal cell. Yeah, clear cellular acanthoma. What if",
"med_umls_ids": "[[{'entity': 'Localized abnormalities', 'concept_id': 'C1844614', 'confidence': 0.7790723443031311}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'somatic mutations', 'concept_id': 'C0544886', 'confidence': 1.0}, {'entity': 'poro', 'concept_id': 'C1012232', 'confidence': 0.8632686734199524}, {'entity': 'cell acanthoma', 'concept_id': 'C0333992', 'confidence': 0.841953456401825}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_515",
"caption_rating": "8"
},
{
"": "1005428",
"caption": "Description of nuclear placement in xanthoma and signet ring cells. Diagnosis of gastric xanthoma and poorly differentiated signet cell carcinoma.",
"image_path": "r7OA0Trj5hQ_image_95f5a715-49dc-467d-bf1f-236523a6de84.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['centrally placed nucleus', 'peripherally pushed nucleus', 'gastric xanthoma', 'signet ring cells', 'poorly differentiated signet cell carcinoma', 'centrally placed nucleus', 'peripherally pushed nucleus', 'gastric xanthoma', 'signet ring cells', 'poorly differentiated signet cell carcinoma']",
"noisy_text": " most of the time centrally placed nucleus. Sometimes it is pushed to the periphery. The central nuclear placement is very important for a diagnosis of xanthoma. For a signet cells, it will be predominantly peripherally pushed nucleus. And when you have doubt, you do a CD68, which will be strongly positive. And so this is a gastric xanthoma. Here, it is more like a signet cells. And when you do cytokeratin, it will all be positive. So it's a poorly differentiated signet cell carcinoma. And there are only three types of pathologists in the world. And this, I got it again from Twitter, I think from",
"corrected_text": " most of the time centrally placed nucleus. Sometimes it is pushed to the periphery. The central nuclear placement is very important for a diagnosis of xanthoma. For a signet cells, it will be predominantly peripherally pushed nucleus. And when you have doubt, you do a CD68, which will be strongly positive. And so this is a gastric xanthoma. Here, it is more like a signet cells. And when you do cytokeratin, it will all be positive. So it's a poorly differentiated signet cell carcinoma. And there are only three types of pathologists in the world. And this, I got it again from Twitter, I think from",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'nuclear', 'concept_id': 'C0521447', 'confidence': 1.0}, {'entity': 'xanthoma', 'concept_id': 'C0302314', 'confidence': 1.0}, {'entity': 'signet ring cells', 'concept_id': 'C0333727', 'confidence': 1.0}, {'entity': 'Diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'gastric xanthoma', 'concept_id': 'C1282522', 'confidence': 1.0}, {'entity': 'poorly differentiated', 'concept_id': 'C0205617', 'confidence': 1.0}, {'entity': 'signet cell carcinoma', 'concept_id': 'C0206696', 'confidence': 0.9410539865493774}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_516",
"caption_rating": "8"
},
{
"": "1007758",
"caption": "Description of a large punch biopsy with an infiltrate filling the dermis and extending into the subcutaneous tissue.",
"image_path": "8S4LeiO6Bbk_image_feb3aa17-235d-4760-9899-94f3bc0c6832.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['brown pigment near the surface', 'infiltrate filling the dermis and extending into the subcutaneous tissue', 'brown pigment near the surface', 'hyperplastic epidermis', 'cellular infiltrate throughout the dermis']",
"noisy_text": " a large punch biopsy. And I think this actually was two punch biopsies from one lesion, each one bisected. And we can see that we've got an infiltrate filling the dermis and extending into the subcutaneous tissue. The infiltrate appears to be compressing the fat rather than growing in between the adipocytes. And I think it's scanning magnification, you know, one of the things that you can really begin to appreciate, not only the fact that this lesion is partially sampled, that it extends to the base and edges of the specimen, but one can begin to appreciate abundant hemorrhage within this tumor. And in addition, we can see some brown pigment near the surface. And common sense will tell you where there's smoke, there's fire. Since we do have all this abundant hemorrhage, there's a high probability that the pigment, this brownish gold pigment that we're seeing up near the surface of the specimen is likely hemocentaurant rather than melanin. But we'll confirm that when we go down to a higher power. As we move in, we can see that the epidermis is slightly hyperplastic. We've got this cellular infiltrate throughout the dermis and we'll need to go down and take a look at this infiltrate. It appears a little less dense at the",
"corrected_text": " a large punch biopsy. And I think this actually was two punch biopsies from one lesion, each one bisected. And we can see that we've got an infiltrate filling the dermis and extending into the subcutaneous tissue. The infiltrate appears to be compressing the fat rather than growing in between the adipocytes. And I think it's scanning magnification, you know, one of the things that you can really begin to appreciate, not only the fact that this lesion is partially sampled, that it extends to the base and edges of the specimen, but one can begin to appreciate abundant hemorrhage within this tumor. And in addition, we can see some brown pigment near the surface. And common sense will tell you where there's smoke, there's fire. Since we do have all this abundant hemorrhage, there's a high probability that the pigment, this brownish gold pigment that we're seeing up near the surface of the specimen is likely hemocentaurant rather than melanin. But we'confirm that when we go down to a higher power. As we move in, we can see that the epidermis is slightly hyperplastic. We've got this cellular infiltrate throughout the dermis and we'll need to go down and take a look at this infiltrate. It appears a little less dense at the",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'punch biopsy', 'concept_id': 'C0182557', 'confidence': 1.0}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'filling', 'concept_id': 'C0178866', 'confidence': 0.7777882218360901}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'subcutaneous tissue', 'concept_id': 'C0222331', 'confidence': 1.0}], [{'entity': 'Excessive', 'concept_id': 'C0442802', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'brown pigment near', 'concept_id': 'C4555503', 'confidence': 0.865685760974884}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}], [{'entity': 'hyperplastic epidermis', 'concept_id': 'C4748317', 'confidence': 0.7633129358291626}, {'entity': 'cellular infiltrate', 'concept_id': 'C1692321', 'confidence': 1.0}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_517",
"caption_rating": "8"
},
{
"": "1005208",
"caption": "Large histiocytes with organisms present within the cytoplasm are seen.",
"image_path": "hoV-JkD6Wb0_image_653124da-8816-48ca-93a4-468df20be9f0.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['cytoplasm', 'organisms', 'infected histiocytes', 'large histiocytes']",
"noisy_text": " we can see that we actually have very large histiocytes. We've cleared out cytoplasm and with a little effort, one could see that there were organisms present within the cytoplasm of these histiocytes producing so-called parasitized histiocytes. And the organisms are very small, one to two microns. And we can use our erythrocyte here as kind of a ruler. Most erythrocytes and lymphocytes have nuclei that have diameters about five to six microns. And so you can see that these round organisms at the periphery of the histiocytes are about one to two microns. And as you'll see in a subsequent slide, when you see parasitized histiocytes with organisms of this size in",
"corrected_text": " we can see that we actually have very large histiocytes. We've cleared out cytoplasm and with a little effort, one could see that there were organisms present within the cytoplasm of these histiocytes producing so-called parasitized histiocytes. And the organisms are very small, one to two microns. And we can use our erythrocyte here as kind of a ruler. Most erythrocytes and lymphocytes have nuclei that have diameters about five to six microns. And so you can see that these round organisms at the periphery of the histiocytes are about one to two microns. And as you'll see in a subsequent slide, when you see parasitized histiocytes with organisms of this size in",
"med_umls_ids": "[[{'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'organisms', 'concept_id': 'C0029235', 'confidence': 0.9999998807907104}, {'entity': 'cytoplasm', 'concept_id': 'C0010834', 'confidence': 1.0}], [{'entity': 'Infected', 'concept_id': 'C0439663', 'confidence': 1.0}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}], [{'entity': 'organisms', 'concept_id': 'C0029235', 'confidence': 0.9999998807907104}, {'entity': 'microns', 'concept_id': 'C0439201', 'confidence': 0.9999999403953552}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}], [{'entity': 'infected', 'concept_id': 'C0439663', 'confidence': 1.0}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'round organisms', 'concept_id': 'C0029235', 'confidence': 0.813967227935791}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'microns', 'concept_id': 'C0439201', 'confidence': 0.9999999403953552}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_518",
"caption_rating": "8"
},
{
"": "1005119",
"caption": "The tumor has an epithelial rather than a mesenchymal origin.",
"image_path": "8S4LeiO6Bbk_image_16dcef57-bfaa-4dd7-9077-d079e0cacb50.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['neoplastic process', 'blue tumor', 'nuclei', 'epithelial tumor', 'cribriform pattern']",
"noisy_text": " again, a very, very nice biopsy. Moving on to slide number three, we're changing directions here. Here we have several fragments of tissue and in looking at this, this is pretty clear that we're dealing with a neoplastic process. It's somewhat fragmented, but seems to be fairly well circumscribed. At scan, one can see that we've got a blue tumor or blue ball present here, and the blue staining is generally due to hematoxylin staining the nucleus. So we've got a lot of nuclei here that we'll want to take a look at. Overall, even though this is fragmented, the fact that it's fairly well circumscribed would indicate that it's got more of a benign silhouette. If we move to higher power, we can see that we're dealing with an epithelial rather than a mosaicable tumor. We've got interconnected cords and strands. We have somewhat of a ribiform pattern here, and",
"corrected_text": " again, a very, very nice biopsy. Moving on to slide number three, we're changing directions here. Here we have several fragments of tissue and in looking at this, this is pretty clear that we're dealing with a neoplastic process. It's somewhat fragmented, but seems to be fairly well circumscribed. At scan, one can see that we've got a blue tumor or blue ball present here, and the blue staining is generally due to hematoxylin staining the nucleus. So we've got a lot of nuclei here that we'll want to take a look at. Overall, even though this is fragmented, the fact that it's fairly well circumscribed would indicate that it's got more of a benign silhouette. If we move to higher power, we can see that we're dealing with an epithelial rather than a mesenchymal tumor. We've got interconnected cords and strands. We have somewhat of a cribriform pattern here, and",
"med_umls_ids": "[[{'entity': 'Neoplastic process', 'concept_id': 'C0027671', 'confidence': 1.0}, {'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'fragments', 'concept_id': 'C0332255', 'confidence': 1.0}], [{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'well-circumscribed', 'concept_id': 'C1707398', 'confidence': 0.9430561065673828}, {'entity': 'blue staining', 'concept_id': 'C0025746', 'confidence': 0.7925992608070374}, {'entity': 'hematoxylin staining', 'concept_id': 'C0018964', 'confidence': 0.9091285467147827}, {'entity': 'nucleus', 'concept_id': 'C0007610', 'confidence': 1.0}], [{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'epithelial', 'concept_id': 'C0221908', 'confidence': 1.0}, {'entity': 'mesenchymal origin', 'concept_id': 'C1513143', 'confidence': 0.8364232778549194}], [{'entity': 'Interconnected', 'concept_id': 'C0683595', 'confidence': 0.8500909209251404}, {'entity': 'cords', 'concept_id': 'C0034869', 'confidence': 0.801885187625885}, {'entity': 'strands', 'concept_id': 'C0600383', 'confidence': 0.800572395324707}, {'entity': 'cribriform pattern', 'concept_id': 'C1333163', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_519",
"caption_rating": "8"
},
{
"": "1004789",
"caption": "Mitosis and apoptosis are also present in the dysplastic epithelium.",
"image_path": "r7OA0Trj5hQ_image_d477ea46-68f9-45cd-bf5a-96f137d0ebee.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Loss of cellular polarity and nuclear stratification reaching the top of the epithelium', 'Dysplasia']",
"noisy_text": " Look at this nuclei running like in this direction. Look at this nuclei running in this direction. So clearly, loss of polarity. And the nuclear stratification is reaching the top of the epithelium, marked apoptosis. It's too thick to see the mitosis, but here you can see the mitosis. So this is stratification, loss of mucin, mitosis, apoptosis. So this is dysplasia. But this dysplasia is the epithelium is reaching the top. And there is loss of polarity. And I don't see probably crib reforming maybe coming here. I don't see in the center of the picture. So I will think",
"corrected_text": " Look at this nuclei running like in this direction. Look at this nuclei running in this direction. So clearly, loss of polarity. And the nuclear stratification is reaching the top of the epithelium, marked apoptosis. It's too thick to see the mitosis, but here you can see the mitosis. So this is stratification, loss of mucin, mitosis, apoptosis. So this is dysplasia. But this dysplasia is the epithelium is reaching the top. And there is loss of polarity. And I don't see probably cribriform maybe coming here. I don't see in the center of the picture. So I will think",
"med_umls_ids": "[[{'entity': 'Loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'cellular polarity', 'concept_id': 'C0085304', 'confidence': 1.0}, {'entity': 'nuclear', 'concept_id': 'C0521447', 'confidence': 1.0}, {'entity': 'stratification', 'concept_id': 'C1514983', 'confidence': 1.0}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'dysplasia', 'concept_id': 'C0334044', 'confidence': 1.0}], [{'entity': 'Mitosis', 'concept_id': 'C0026255', 'confidence': 0.9999998807907104}, {'entity': 'apoptosis', 'concept_id': 'C0162638', 'confidence': 1.0}, {'entity': 'dysplastic epithelium', 'concept_id': 'C1512100', 'confidence': 0.8234760165214539}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_520",
"caption_rating": "8"
},
{
"": "1009078",
"caption": "Inflammatory bowel disease is not likely based on the cytology.",
"image_path": "sDFjOtMAYrk_image_7d5336a2-b407-43a5-865b-ee33a577ea03.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['prominent nucleoli', 'reactive cytologic atypia', 'chemotherapy or radiation', 'cancer', 'inflammatory bowel disease']",
"noisy_text": " I'm missing it. Okay. I think what's catching my eye for the most part is the prominent nucleolide, but what would you say about the NC ratio? Yeah, I think overall it's low. You have lots, loads of cytoplasm. Even though the nuclei are big, you have loads of cytoplasm. So, with this morphology, first of all, the question was, you know, inflammatory bowel disease. Okay, maybe, but the cytology is not great for the degree of reactive epithelial changes. Although you can have some crazy looking inflammatory bowel disease cases, it's really crazy. When I see crazy bizarre epithelial atypia, I think about treatment effect, either chemotherapy or radiation. Both of them can give you this crazy cytologic atypia that sometimes may actually make you think of cancer. We've got a couple of cases received in consultation. I'm remembering one specifically in the stomach where the question is, what about this cancer? And it wasn't. It was just crazy reactive epithelial changes in a patient who we didn't know, but the patient had received radiotherapy for lung cancer. And it definitely looked a lot like malignancy, but there was something not right about it. So, this patient was receiving at the same time chemotherapy for his pancreatic cancer. One thing you can see in patients, especially when they're receiving radiation,",
"corrected_text": " I'm missing it. Okay. I think what's catching my eye for the most part is the prominent nucleoli, but what would you say about the NC ratio? Yeah, I think overall it's low. You have lots, loads of cytoplasm. Even though the nuclei are big, you have loads of cytoplasm. So, with this morphology, first of all, the question was, you know, inflammatory bowel disease. Okay, maybe, but the cytology is not great for the degree of reactive epithelial changes. Although you can have some crazy looking inflammatory bowel disease cases, it's really crazy. When I see crazy bizarre epithelial atypia, I think about treatment effect, either chemotherapy or radiation. Both of them can give you this reactive cytologic atypia that sometimes may actually make you think of cancer. We've got a couple of cases received in consultation. I'm remembering one specifically in the stomach where the question is, what about this cancer? And it wasn't. It was just crazy reactive epithelial changes in a patient who we didn't know, but the patient had received radiotherapy for lung cancer. And it definitely looked a lot like malignancy, but there was something not right about it. So, this patient was receiving at the same time chemotherapy for his pancreatic cancer. One thing you can see in patients, especially when they're receiving radiation,",
"med_umls_ids": "[[{'entity': 'Prominent', 'concept_id': 'C0205402', 'confidence': 0.9999999403953552}, {'entity': 'nucleoli', 'concept_id': 'C0007609', 'confidence': 0.8710004091262817}, {'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'NC', 'concept_id': 'C0027964', 'confidence': 1.0}, {'entity': 'ratio', 'concept_id': 'C0456603', 'confidence': 1.0}, {'entity': 'low', 'concept_id': 'C0205251', 'confidence': 0.9999999403953552}], [{'entity': 'Reactive cytologic atypia', 'concept_id': 'C0333865', 'confidence': 0.8587049245834351}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'treatment effect', 'concept_id': 'C1518681', 'confidence': 1.0}, {'entity': 'chemotherapy', 'concept_id': 'C0013216', 'confidence': 1.0}, {'entity': 'radiation', 'concept_id': 'C0034519', 'confidence': 1.0}], [{'entity': 'Crazy', 'concept_id': 'C0424157', 'confidence': 0.6988691687583923}, {'entity': 'cancer', 'concept_id': 'C0006826', 'confidence': 0.9999998807907104}], [{'entity': 'Inflammatory bowel disease', 'concept_id': 'C0021390', 'confidence': 1.0}, {'entity': 'cytology', 'concept_id': 'C0010818', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_521",
"caption_rating": "8"
},
{
"": "1005837",
"caption": "Elliptical excision was taken and cut into bread loaves for histological examination.",
"image_path": "LlPaENuqzVQ_image_3897d7c3-22c9-460e-a0dd-32bf7153b6af.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " All right, who wants to give this one a go? Hello, can you hear me? Yeah. Looks like we have multiple deep shaves. Well, wait a second. You've been in the surgery clinic before and you've done a lot of biopsies in your long career now. So this, you think it's really a shave? I take that back. It's probably excision or incisional biopsy. Yeah, yeah, yes, good. This is an excision. So they basically took the elliptical excision. They cut it into bread loaves and put it all on one slide. So that's how",
"corrected_text": " All right, who wants to give this one a go? Hello, can you hear me? Yeah. Looks like we have multiple deep shaves. Well, wait a second. You've been in the surgery clinic before and you've done a lot of biopsies in your long career now. So this, you think it's really a shave? I take that back. It's probably excision or incisional biopsy. Yeah, yeah, yes, good. This is an excision. So they basically took the elliptical excision. They cut it into bread loaves and put it all on one slide. So that's how",
"med_umls_ids": "[[{'entity': 'Multiple', 'concept_id': 'C0439064', 'confidence': 1.0}, {'entity': 'deep shaves', 'concept_id': 'C0518505', 'confidence': 0.7456271648406982}, {'entity': 'excisional/incisional biopsy', 'concept_id': 'C0184921', 'confidence': 0.7826999425888062}], [{'entity': 'Elliptical excision', 'concept_id': 'C1707902', 'confidence': 0.8901858329772949}, {'entity': 'bread', 'concept_id': 'C0006138', 'confidence': 1.0}, {'entity': 'histological examination', 'concept_id': 'C0019637', 'confidence': 0.9535407423973083}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_522",
"caption_rating": "8"
},
{
"": "1004447",
"caption": "There is an eosinophilic component to the biopsy.",
"image_path": "udoW6VSqsm4_image_59d0e5dd-f50c-497c-afb3-e8743731f6f9.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " Okay, so here we have a punch biopsy, non-equal skin. What we can see is there is a more sparse, moderate, and full trait in the superficial and deep dermis, and into the fat as well. And there's some eosinophilic component to it as well. Okay, what's the overall pattern? It's probably a superficial and deep, almost like a little funiculitis. It does go into the fat, and perivascular and interstitial. Yeah, and interstitial. And notice that there's no epidermal involved. No, epidermis is completely sparse. Even higher magnification. Now what do you see? Now I",
"corrected_text": " Okay, so here we have a punch biopsy, non-equal skin. What we can see is there is a more sparse, moderate, and full trait in the superficial and deep dermis, and into the fat as well. And there's some eosinophilic component to it as well. Okay, what's the overall pattern? It's probably a superficial and deep, almost like a little funiculitis. It does go into the fat, and perivascular and interstitial. Yeah, and interstitial. And notice that there's no epidermal involved. No, epidermis is completely sparse. Even higher magnification. Now what do you see? Now I",
"med_umls_ids": "[[{'entity': 'Punch biopsy', 'concept_id': 'C0182557', 'confidence': 1.0}, {'entity': 'normal skin', 'concept_id': 'C0558145', 'confidence': 1.0}, {'entity': 'moderate', 'concept_id': 'C0205081', 'confidence': 1.0}, {'entity': 'trait', 'concept_id': 'C0599883', 'confidence': 1.0}, {'entity': 'superficial', 'concept_id': 'C0205124', 'confidence': 1.0}, {'entity': 'deep dermis', 'concept_id': 'C0205125', 'confidence': 0.7651135921478271}, {'entity': 'fat', 'concept_id': 'C0015677', 'confidence': 1.0}], [{'entity': 'eosinophilic', 'concept_id': 'C0333930', 'confidence': 1.0}, {'entity': 'component', 'concept_id': 'C0449432', 'confidence': 1.0}, {'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}], [{'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}, {'entity': 'consistent with', 'concept_id': 'C0332290', 'confidence': 1.0}, {'entity': 'superficial', 'concept_id': 'C0205124', 'confidence': 1.0}, {'entity': 'deep funiculitis', 'concept_id': 'C0241216', 'confidence': 0.7899089455604553}, {'entity': 'perivascular', 'concept_id': 'C0442165', 'confidence': 1.0}, {'entity': 'interstitial regions', 'concept_id': 'C0596790', 'confidence': 0.7848911285400391}], [{'entity': 'involvement', 'concept_id': 'C1314939', 'confidence': 1.0}, {'entity': 'epidermis', 'concept_id': 'C0014520', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_523",
"caption_rating": "7"
},
{
"": "1007827",
"caption": "Proximal biopsies are normal endoscopically and histologically.",
"image_path": "sDFjOtMAYrk_image_52a027e7-1248-49df-9d15-123a08cfbffe.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "[]",
"noisy_text": " Yeah. Nope. Endoscopically and histologically, proximal biopsies are normal. Yeah. So the clinical also, if you know what the endoscopic procedure show, that's really, really helpful. You know, the patient's male. Have I had cases in females? No. Have I tried to give females STI proctitis? Yes. Have I been running every single case? Yes. Are there cases reported of patients with rectal chlamydia? Yes, but I have not come across. I'm the only one that we had turned out to be a transgender female. Another, you know, episode where I went down the tubes is I suggested the possibility of STI proctitis in this male patient because it really looked like STI proctitis. A year later, he gets another biopsy and it's full blown IBD. So early in the course of IBD, STI proctitis can really, the cases can look a lot like STI proctitis. So yeah. And this is a patient with chlamydia. I'm sorry, the slide is a little bit faded. I don't know why because it's from 2015, but this is just goes to show you how the pattern of inflammation and distortion is",
"corrected_text": " Yeah. Nope. Endoscopically and histologically, proximal biopsies are normal. Yeah. So the clinical also, if you know what the endoscopic procedure show, that's really, really helpful. You know, the patient's male. Have I had cases in females? No. Have I tried to give females STI proctitis? Yes. Have I been running every single case? Yes. Are there cases reported of patients with rectal chlamydia? Yes, but I have not come across. I'm the only one that we had turned out to be a transgender female. Another, you know, episode where I went down the tubes is I suggested the possibility of STI proctitis in this male patient because it really looked like STI proctitis. A year later, he gets another biopsy and it's full active IBD. So early in the course of IBD, STI proctitis can really, the cases can look a lot like STI proctitis. So yeah. And this is a patient with chlamydia. I'm sorry, the slide is a little bit faded. I don't know why because it's from 2015, but this is just goes to show you how the pattern of inflammation and distortion is",
"med_umls_ids": "[[{'entity': 'Proximal', 'concept_id': 'C0205107', 'confidence': 0.9999999403953552}, {'entity': 'biopsies', 'concept_id': 'C0005558', 'confidence': 1.0}, {'entity': 'endoscopically', 'concept_id': 'C0014245', 'confidence': 0.7536628842353821}, {'entity': 'histologically', 'concept_id': 'C0205462', 'confidence': 1.0}], [{'entity': 'STI', 'concept_id': 'C0036916', 'confidence': 1.0}, {'entity': 'proctitis', 'concept_id': 'C0033246', 'confidence': 0.9999999403953552}, {'entity': 'early', 'concept_id': 'C1279919', 'confidence': 1.0}, {'entity': 'IBD', 'concept_id': 'C0021390', 'confidence': 1.0}], [{'entity': 'Cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'rectal chlamydia', 'concept_id': 'C0008148', 'confidence': 0.8654578924179077}], [{'entity': 'Pattern', 'concept_id': 'C0449774', 'confidence': 1.0}, {'entity': 'inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}, {'entity': 'patients', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'chlamydia', 'concept_id': 'C0008148', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_524",
"caption_rating": "9"
},
{
"": "1005289",
"caption": "Benign nature of the glands despite the presence of basal cell hyperplasia",
"image_path": "iklRyY1nBIE_image_018f29b1-c570-497d-9129-98642a46a135.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " That's something very important you want to exclude. But this is not melanoma. The patient did not have a history of melanoma. This does not look like prostate cancer, even though it can have sarcomatoid prostate cancer or prostatic adenocarcinoma with sarcomatoid features, which I'll share with you shortly. But there are a number of things that need to come into the differential. Something else you may have observed with this case is the fact that it's not just a stroma process. It looks like there's something else going on in the glands, too. And in the glands, it's almost like there's a crosstalk between the stroma process and the glands. The glands are benign, but they actually have what looks like basal cell hyperplasia in areas. And that's not uncommon with this entity. It is not unusual to have this entity, actually, with basal",
"corrected_text": " That's something very important you want to exclude. But this is not melanoma. The patient did not have a history of melanoma. This does not look like prostate cancer, even though it can have sarcomatoid prostate cancer or prostatic adenocarcinoma with sarcomatoid features, which I'share with you shortly. But there are a number of things that need to come into the differential. Something else you may have observed with this case is the fact that it's not just a stroma process. It looks like there's something else going on in the glands, too. And in the glands, it's almost like there's a crosstalk between the stroma process and the glands. The glands are benign, but they actually have what looks like basal cell hyperplasia in areas. And that's not uncommon with this entity. It is not unusual to have this entity, actually, with basal",
"med_umls_ids": "[[{'entity': 'Exclusion', 'concept_id': 'C0680251', 'confidence': 0.9999999403953552}, {'entity': 'melanoma', 'concept_id': 'C0025202', 'confidence': 1.0}, {'entity': 'prostate cancer', 'concept_id': 'C0376358', 'confidence': 1.0}, {'entity': 'sarcomatoid', 'concept_id': 'C0205697', 'confidence': 0.8252997994422913}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'differential diagnosis', 'concept_id': 'C0011906', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'crosstalk', 'concept_id': 'C0010357', 'confidence': 1.0}, {'entity': 'stroma', 'concept_id': 'C0927195', 'confidence': 1.0}, {'entity': 'process', 'concept_id': 'C1184743', 'confidence': 1.0}, {'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'basal cell hyperplasia', 'concept_id': 'C0333990', 'confidence': 1.0}], [{'entity': 'Benign', 'concept_id': 'C0205183', 'confidence': 1.0}, {'entity': 'nature', 'concept_id': 'C0349590', 'confidence': 1.0}, {'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'basal cell hyperplasia', 'concept_id': 'C0333990', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_525",
"caption_rating": "7"
},
{
"": "1009266",
"caption": "Involvement around damaged nerves is a common feature of sarcoid granulomatous inflammation.",
"image_path": "udoW6VSqsm4_image_f5d32450-1d57-43e4-a560-1a822381f3a3.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['sarcoid granulomatous inflammation', 'involvement around nerves']",
"noisy_text": " That's the tuberculoid. Yeah, good. The tuberculoid form of leprosy gives you sarcoidal granulomatous inflammation. It's elongated. Very good. That's exactly right. What else can give you sarcoidal granulomatous inflammation? Can I ask a quick question about the sarcoid with the two... The nansins? So, I had a case, I saw a case that looked kind of horizontal, but it was sarcoid. And so, what other ways can you tell? Sometimes it can be difficult, but usually you're going to see involvement around nerves damaged nerves. You're about to get sarcoidal granulomatous inflammation. They always have very high risk inflammatory reactions. They just wipe out the nerves. So, that's helpful. Wasn't",
"corrected_text": " That's the tuberculoid. Yeah, good. The tuberculoid form of leprosy gives you sarcoidal granulomatous inflammation. It's elongated. Very good. That's exactly right. What else can give you sarcoidal granulomatous inflammation? Can I ask a quick question about the sarcoid with the two... The sarcoidosis? So, I had a case, I saw a case that looked kind of horizontal, but it was sarcoid. And so, what other ways can you tell? Sometimes it can be difficult, but usually you're going to see involvement around nerves damaged nerves. You're about to get sarcoidal granulomatous inflammation. They always have very high risk inflammatory reactions. They just wipe out the nerves. So, that's helpful. Wasn't",
"med_umls_ids": "[[{'entity': 'Tuberculoid', 'concept_id': 'C0544783', 'confidence': 0.8459237217903137}, {'entity': 'leprosy', 'concept_id': 'C0023343', 'confidence': 1.0}, {'entity': 'sarcoid', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'granulomatous inflammation', 'concept_id': 'C0553697', 'confidence': 1.0}], [{'entity': 'Involvement', 'concept_id': 'C1314939', 'confidence': 1.0}, {'entity': 'damaged nerves', 'concept_id': 'C3887709', 'confidence': 0.8087002038955688}, {'entity': 'sarcoid', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'granulomatous inflammation', 'concept_id': 'C0553697', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_526",
"caption_rating": "8"
},
{
"": "1004210",
"caption": "The tissue sample contains nail bed and matrix epithelium.",
"image_path": "8S4LeiO6Bbk_image_5f174254-0490-4295-ae0c-e926e4473247.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['nail bed', 'matrix epithelium', 'melanocytes forming nests', 'pagetoid pattern', 'basal layer of the matrix', 'upper portions of the matrix']",
"noisy_text": " we've got nail bed and matricle epithelium. I believe this must be some nail fold, a portion of the nail fold, and then in the bottom piece of tissue in these sections we actually have matricle epithelium and you can see the rete or somewhat hyperplastic. And on higher power examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matricle epithelium in the matricle layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that",
"corrected_text": " we've got nail bed and matrix epithelium. I believe this must be some nail fold, a portion of the nail fold, and then in the bottom piece of tissue in these sections we actually have matrix epithelium and you can see the rete or somewhat hyperplastic. And on higher power examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matrix epithelium in the matrix layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that",
"med_umls_ids": "[[{'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'nail', 'concept_id': 'C0027342', 'confidence': 1.0}, {'entity': 'matrix epithelium', 'concept_id': 'C0014609', 'confidence': 0.7584323883056641}], [{'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'nests', 'concept_id': 'C0035253', 'confidence': 0.7275967001914978}, {'entity': 'upper portions', 'concept_id': 'C0449719', 'confidence': 0.6251541972160339}, {'entity': 'matrix', 'concept_id': 'C0331858', 'confidence': 1.0}, {'entity': 'pagetoid', 'concept_id': 'C1518847', 'confidence': 0.8801172375679016}, {'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}], [{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'matrix layer', 'concept_id': 'C0331858', 'confidence': 0.71736741065979}, {'entity': 'suspicious', 'concept_id': 'C0750493', 'confidence': 1.0}, {'entity': 'melanoma', 'concept_id': 'C0025202', 'confidence': 1.0}, {'entity': 'in situ', 'concept_id': 'C0444498', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_527",
"caption_rating": "8"
},
{
"": "1006205",
"caption": "Histopathological description of a tumor with interconnected cords and strands, cribriform pattern, loose and edematous vascular stroma, and at least two cell types in the epithelial islands.",
"image_path": "8S4LeiO6Bbk_image_bcdaf0fd-b7ab-4e36-853b-eb7f0e43a144.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['nuclei']",
"noisy_text": " and the blue staining is generally due to hematoxylin staining the nucleus. So we've got a lot of nuclei here that we'll want to take a look at. Overall, even though this is fragmented, the fact that it's fairly well circumscribed would indicate that it's got more of a benign silhouette. If we move to higher power, we can see that we're dealing with an epithelial rather than a mosaicable tumor. We've got interconnected cords and strands. We have somewhat of a ribiform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of",
"corrected_text": " and the blue staining is generally due to hematoxylin staining the nucleus. So we've got a lot of nuclei here that we'll want to take a look at. Overall, even though this is fragmented, the fact that it's fairly well circumscribed would indicate that it's got more of a benign silhouette. If we move to higher power, we can see that we're dealing with an epithelial rather than a mucinous tumor. We've got interconnected cords and strands. We have somewhat of a cribriform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'cords', 'concept_id': 'C0034869', 'confidence': 0.801885187625885}, {'entity': 'strands', 'concept_id': 'C0600383', 'confidence': 0.800572395324707}, {'entity': 'cribriform pattern', 'concept_id': 'C1333163', 'confidence': 1.0}, {'entity': 'loose', 'concept_id': 'C0205407', 'confidence': 1.0}, {'entity': 'edematous', 'concept_id': 'C0013604', 'confidence': 1.0}, {'entity': 'cell types', 'concept_id': 'C0007634', 'confidence': 1.0}, {'entity': 'epithelial islands', 'concept_id': 'C0221908', 'confidence': 0.675740122795105}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_528",
"caption_rating": "9"
},
{
"": "1008698",
"caption": "Identification of the cell type responsible for producing protein fibers and ground substance in connective tissue.",
"image_path": "ib991vTA67A_image_4ad96366-3195-4299-85ca-1e2b799b8a27.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Head and Neck']",
"roi_text": "['scattered little nuclei', 'cell type making protein fibers and ground substance in connective tissue', 'scattered little nuclei', 'cell type making protein fibers and ground substance in connective tissue', 'scattered little nuclei', 'cell type making protein fibers and ground substance in connective tissue']",
"noisy_text": " So here's, here's, here's this one. So number sixteen, what is this Connective Tissue and tell me the name of the scattered little nuclei, we see the nuclei all throughout here. Most of these nuclei belong to what cell, that cell is making the protein fibers and the ground substance in this Connective Tissue. So what cell type is living in here that's making these protein fibers and the ground substance in this Connective Tissue? That was number sixteen. Here's this one, seeing it again, this one's not quite as clear, you can see the protein fibers here,",
"corrected_text": " So here's, here's, here's this one. So number sixteen, what is this Connective Tissue and tell me the name of the scattered little nuclei, we see the nuclei all throughout here. Most of these nuclei belong to what cell, that cell is making the protein fibers and the ground substance in this Connective Tissue. So what cell type is living in here that's making these protein fibers and the ground substance in this Connective Tissue? That was number sixteen. Here's this one, seeing it again, this one's not quite as clear, you can see the protein fibers here,",
"med_umls_ids": "[[{'entity': 'Identification', 'concept_id': 'C0020792', 'confidence': 1.0}, {'entity': 'cell type', 'concept_id': 'C0007634', 'confidence': 1.0}, {'entity': 'protein fibers', 'concept_id': 'C0000696', 'confidence': 0.7645217180252075}, {'entity': 'ground substance', 'concept_id': 'C1253945', 'confidence': 1.0}, {'entity': 'connective tissue', 'concept_id': 'C0009780', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1152.0",
"id": "test_529",
"caption_rating": "8"
},
{
"": "1005915",
"caption": "Well-defined nerve fascicles with spindle-shaped cells, which are positive with S100 and SOX10, defining the diagnosis of rudimentary supernumerary digit.",
"image_path": "8S4LeiO6Bbk_image_ad937ed9-c964-4790-801d-07e966b97fd9.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['nerve fascicles', 'spindle-shaped cells', 'rudimentary supernumerary digit', 'ulnar aspect of the fifth digit', 'acquired digital fibroma', 'acquired digital fibrokeratoma', 'trichilemmal cyst']",
"noisy_text": " core here we've got several well-defined nerve fascicles and the spindled cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions of course tend to occur along the ulnar eye aspect of the fifth digit. They're not infrequently bilateral and the key differential here of course is an acquired digital fibroma or an acquired digital fibrocarotoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if",
"corrected_text": " core here we've got several well-defined nerve fascicles and the spindle cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions of course tend to occur along the ulnar eye aspect of the fifth digit. They're not infrequently bilateral and the key differential here of course is an acquired digital fibroma or an acquired digital fibrokeratoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if",
"med_umls_ids": "[[{'entity': 'Well-defined nerve fascicles', 'concept_id': 'C1185741', 'confidence': 0.5682494640350342}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'S100', 'concept_id': 'C3273837', 'confidence': 1.0}, {'entity': 'SOX10', 'concept_id': 'C1420317', 'confidence': 0.9999998807907104}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'rudimentary supernumerary digit', 'concept_id': 'C0152427', 'confidence': 0.8142021894454956}], [{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'ulnar', 'concept_id': 'C0442044', 'confidence': 1.0}, {'entity': 'aspect', 'concept_id': 'C1547011', 'confidence': 1.0}, {'entity': 'fifth digit', 'concept_id': 'C0230403', 'confidence': 0.912693440914154}, {'entity': 'bilateral', 'concept_id': 'C0238767', 'confidence': 1.0}], [{'entity': 'differential diagnosis', 'concept_id': 'C0011906', 'confidence': 1.0}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}, {'entity': 'digital fibroma', 'concept_id': 'C4538745', 'confidence': 0.8997364640235901}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}], [{'entity': 'Trichilemmal cyst', 'concept_id': 'C2266788', 'confidence': 1.0}, {'entity': 'biopsy specimen', 'concept_id': 'C0677862', 'confidence': 1.0}, {'entity': 'slide number', 'concept_id': 'C3828004', 'confidence': 0.8261933326721191}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_530",
"caption_rating": "8"
},
{
"": "1008937",
"caption": "The size of the particles within the histiocytes is markedly variable.",
"image_path": "8S4LeiO6Bbk_image_cc7d42e4-f76c-4df4-843a-cf0b51945268.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Pigmented histiocytes with hemocyanin pigment', 'Extravasated erythrocytes', 'Size of particles within histiocytes', 'Size of particles within histiocytes']",
"noisy_text": " in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes as suspected is hemocentaurant. If you notice, it's got kind of that golden brown color. If you had a sub-stage condenser or a fine focus knob, you would see that it's somewhat refractile, but unfortunately, we can't use that particular tool when we're looking at scanned images. But one clue to the fact that we're dealing with hemocentaurant rather than melanin, not only is the presence of extravasated erythrocytes, but if you look at the size of the particles within the histiocytes, they're markedly variable. So the hemocentaurant is of course a breakdown product of the RBCs. And you can see that we've got small granules next to very large, chunky granules. Melanin pigment on the other hand, which of course can be found in melanophages or histiocytes containing the particles, the melanin granules tend to be more uniform in size. And of course, one can always do special stains, an iron stain, such as Prussian blue or pearls for hemocentaurant and a Fontanumus song stain for melanin pigment. So in any case, getting back to the to the lesion in question, we've got a lot of hemocentaurant-laden histiocytes here. We've also got, in other areas, fascicles, kind of randomly oriented of histiocytes and fibrocytes with oval",
"corrected_text": " in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes as suspected is hemocyanin. If you notice, it's got kind of that golden brown color. If you had a sub-stage condenser or a fine focus knob, you would see that it's somewhat refractile, but unfortunately, we can't use that particular tool when we're looking at scanned images. But one clue to the fact that we're dealing with hemocyanin rather than melanin, not only is the presence of extravasated erythrocytes, but if you look at the size of the particles within the histiocytes, they're markedly variable. So the hemocyanin is of course a breakdown product of the RBCs. And you can see that we've got small granules next to very large, chunky granules. Melanin pigment on the other hand, which of course can be found in melanophages or histiocytes containing the particles, the melanin granules tend to be more uniform in size. And of course, one can always do special stains, an iron stain, such as Prussian blue or pearls for hemocyanin and a Fontana-Masson stain for melanin pigment. So in any case, getting back to the to the lesion in question, we've got a lot of hemocyanin-laden histiocytes here. We've also got, in other areas, fascicles, kind of randomly oriented of histiocytes and fibrocytes with oval",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'pigment', 'concept_id': 'C0031911', 'confidence': 1.0}, {'entity': 'breakdown', 'concept_id': 'C0699900', 'confidence': 0.9999999403953552}, {'entity': 'product', 'concept_id': 'C1254351', 'confidence': 1.0}, {'entity': 'RBCs', 'concept_id': 'C0014792', 'confidence': 1.0}], [{'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'particles', 'concept_id': 'C0597177', 'confidence': 1.0}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'variable', 'concept_id': 'C0439828', 'confidence': 1.0}], [{'entity': 'Melanin', 'concept_id': 'C0025196', 'confidence': 1.0}, {'entity': 'pigment', 'concept_id': 'C0031911', 'confidence': 1.0}, {'entity': 'uniform', 'concept_id': 'C0205375', 'confidence': 1.0}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}], [{'entity': 'Special stains', 'concept_id': 'C0038128', 'confidence': 0.7105166912078857}, {'entity': 'Prussian blue', 'concept_id': 'C0060234', 'confidence': 1.0}, {'entity': 'Fontana-Masson', 'concept_id': 'C0060631', 'confidence': 0.9090515375137329}, {'entity': 'confirm', 'concept_id': 'C0521093', 'confidence': 1.0}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}, {'entity': 'pigment', 'concept_id': 'C0031911', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_531",
"caption_rating": "8"
},
{
"": "1006251",
"caption": "Multinucleated giant cells are foreign body giant cells seen around foreign material that cannot be easily phagocytosed or destroyed.",
"image_path": "rHSTVT91c8Q_image_dce55910-0eb2-475d-928a-24c30c1dd36e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Cardiac', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Brown pigment which is very probably hemosiderin', 'Foreign body giant cells seen around some foreign material', 'Brown pigment which is very probably hemosiderin']",
"noisy_text": " multinucleated giant cells are actually transformed macrophages and they are also called foreign body cells or those are those are cells seen around some foreign material that cannot be easily phagocytosed or destroyed and they are transformed macrophages. Here we can see some brown pigment which is very probably hemosiderin and if we want to be sure we can use prussian blue stain or pearls pearls stain and the hemosiderin would turn into blue pigment because of iron ions that mediates this blue reaction. Macrophages that phagocytose the hemosiderin are sometimes called siderophages. Here",
"corrected_text": " multinucleated giant cells are actually transformed macrophages and they are also called foreign body cells or those are those are cells seen around some foreign material that cannot be easily phagocytosed or destroyed and they are transformed macrophages. Here we can see some brown pigment which is very probably hemosiderin and if we want to be sure we can use prussian blue stain or pearls pearls stain and the hemosiderin would turn into blue pigment because of iron ions that mediates this blue reaction. Macrophages that phagocytose the hemosiderin are sometimes called siderophages. Here",
"med_umls_ids": "[[{'entity': 'Multinucleated giant cells', 'concept_id': 'C0017526', 'confidence': 0.9999999403953552}, {'entity': 'foreign body giant cells', 'concept_id': 'C0017527', 'confidence': 1.0}, {'entity': 'foreign material', 'concept_id': 'C0016542', 'confidence': 1.0}, {'entity': 'phagocytosed', 'concept_id': 'C0031308', 'confidence': 0.920818030834198}, {'entity': 'destroyed', 'concept_id': 'C3830528', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_532",
"caption_rating": "8"
},
{
"": "1008735",
"caption": "Presence of at least two cell types with round to oval nuclei and faint eosinophilic to pale gray cytoplasm.",
"image_path": "8S4LeiO6Bbk_image_f67d5747-1b9d-404c-8cc5-a2bb75b7f620.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['epithelial tumor', 'cytoplasm', 'vesicular chromatin pattern', 'lymphocytes', 'duct formation', 'epithelial tumor', 'cytoplasm', 'vesicular chromatin pattern', 'lymphocytes', 'duct formation']",
"noisy_text": " If we move to higher power, we can see that we're dealing with an epithelial rather than a mosaicable tumor. We've got interconnected cords and strands. We have somewhat of a ribiform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of the cells are round to oval. They're fairly large. These cells have some faint eosinophilic to pale gray cytoplasm, although this cytoplasm is kind of difficult to see. Some of these cells have an evenly dispersed or vesicular chromatin pattern, and other nuclei are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and",
"corrected_text": " If we move to higher power, we can see that we're dealing with an epithelial rather than a mesenchymal tumor. We've got interconnected cords and strands. We have somewhat of a cribriform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of the cells are round to oval. They're fairly large. These cells have some faint eosinophilic to pale gray cytoplasm, although this cytoplasm is kind of difficult to see. Some of these cells have an evenly dispersed or vesicular chromatin pattern, and other nuclei are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'epithelial tumor', 'concept_id': 'C1368683', 'confidence': 0.9999999403953552}, {'entity': 'cords', 'concept_id': 'C0034869', 'confidence': 0.801885187625885}, {'entity': 'strands', 'concept_id': 'C0600383', 'confidence': 0.800572395324707}], [{'entity': 'Cribriform pattern', 'concept_id': 'C1333163', 'confidence': 1.0}, {'entity': 'loose', 'concept_id': 'C0205407', 'confidence': 1.0}, {'entity': 'edematous', 'concept_id': 'C0013604', 'confidence': 1.0}, {'entity': 'vascular stroma', 'concept_id': 'C0005847', 'confidence': 0.8046398758888245}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'cell types', 'concept_id': 'C0007634', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'eosinophilic', 'concept_id': 'C0333930', 'confidence': 1.0}, {'entity': 'pale', 'concept_id': 'C0030232', 'confidence': 1.0}, {'entity': 'gray cytoplasm', 'concept_id': 'C0010834', 'confidence': 0.8177905678749084}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'duct', 'concept_id': 'C0687028', 'confidence': 1.0}, {'entity': 'formation', 'concept_id': 'C0220781', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_533",
"caption_rating": "8"
},
{
"": "1004786",
"caption": "The narrator is discussing pigmented Bowen\u2019s disease, which can resemble other benign skin conditions but must be checked for orderly maturation to differentiate it from squamous cell carcinoma.",
"image_path": "8S4LeiO6Bbk_image_8c36ddc3-2ca4-41c0-ba10-e244e318a521.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['pigmented Bowen\u2019s disease', 'psoriasis form dermatitis', 'inflamed pigmented seborrheic keratosis', 'squamous cell carcinoma', 'interface dermatitis', 'pigmented Bowen\u2019s disease', 'psoriasis form dermatitis', 'inflamed pigmented seborrheic keratosis', 'squamous cell carcinoma', 'interface dermatitis']",
"noisy_text": " of pigmented Bowen's disease or pigmented squamous cell carcinoma. One could see similar changes in lesions too of boenoid papillosis and if this was one of many or a few papules on the genitalia one would have to keep boenoid papillosis and the differential as well here but this is one of these lesions that kind of is a fooler because it has a benign silhouette, resembles a psoriasis form dermatitis or even an inflamed pigmented seborrheic keratosis but it always behooves you to go down and check to make sure that you've got orderly maturation because architecturally Bowen's disease can resemble a benign keratosis. So, pigmented Bowen's disease in this case. Moving on to slide number eight. Slide number eight is the first of two interface dermatitis that we're",
"corrected_text": " of pigmented Bowen's disease or pigmented squamous cell carcinoma. One could see similar changes in lesions too of bowenoid papulosis and if this was one of many or a few papules on the genitalia one would have to keep bowenoid papulosis and the differential as well here but this is one of these lesions that kind of is a fooler because it has a benign silhouette, resembles a psoriasis form dermatitis or even an inflamed pigmented seborrheic keratosis but it always behooves you to go down and check to make sure that you've got orderly maturation because architecturally squamous cell carcinoma's disease can resemble a benign keratosis. So, pigmented Bowen's disease in this case. Moving on to slide number eight. Slide number eight is the first of two interface dermatitis that we're",
"med_umls_ids": "[[{'entity': 'narrator', 'concept_id': 'C1135957', 'confidence': 0.7711340188980103}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'Bowen\u2019s disease', 'concept_id': 'C0006079', 'confidence': 0.9730859994888306}, {'entity': 'benign', 'concept_id': 'C0205183', 'confidence': 1.0}, {'entity': 'maturation', 'concept_id': 'C0678723', 'confidence': 1.0}, {'entity': 'differentiate', 'concept_id': 'C0205615', 'confidence': 0.9999998807907104}, {'entity': 'squamous cell carcinoma', 'concept_id': 'C0007137', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_534",
"caption_rating": "8"
},
{
"": "1006438",
"caption": "The glomerulus is compressed and surrounded by a crescent, which can be classified as either a fibrous crescent or a fibrous cellular crescent. The sample shown has both types of crescents present.",
"image_path": "WhnEXkBN4D8_image_96720733-883a-441c-8c53-78f26aca6029.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Renal', 'Hematopathology', 'Soft tissue']",
"roi_text": "['Compressed glomerulus surrounded by a crescent, with both fibrous and cellular components.', 'Compressed glomerulus surrounded by a crescent, with both fibrous and cellular components.']",
"noisy_text": " Look at this glomeruli. This is the capsule. Everything else is compressed. So can I call this a beautiful crescent? Yes. So as a pathologist, when you compare the crescent, you have to say whether it's a fibrous crescent or a fibrous cellular crescent because that also makes sense here. Here, I do have half of them. It's more of acellular area fibrous and here I do have cellularity as well. Look at this. My glomerulus is here. It's only in one pole. Rest everything is replaced by cellular crescent, right? Because like",
"corrected_text": " Look at this glomerulus. This is the capsule. Everything else is compressed. So can I call this a beautiful crescent? Yes. So as a pathologist, when you compare the crescent, you have to say whether it's a fibrous crescent or a fibrous cellular crescent because that also makes sense here. Here, I do have half of them. It's more of fibrous crescent and here I do have cellularity as well. Look at this. My glomerulus is here. It's only in one pole. Rest everything is replaced by cellular crescent, right? Because like",
"med_umls_ids": "[[{'entity': 'glomerulus', 'concept_id': 'C0022663', 'confidence': 1.0}, {'entity': 'compressed', 'concept_id': 'C0332260', 'confidence': 1.0}, {'entity': 'surrounded', 'concept_id': 'C1282914', 'confidence': 1.0}, {'entity': 'crescent', 'concept_id': 'C0444628', 'confidence': 1.0}, {'entity': 'fibrous crescent', 'concept_id': 'C0439709', 'confidence': 0.6849074363708496}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}, {'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'crescents', 'concept_id': 'C0444628', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_535",
"caption_rating": "9"
},
{
"": "1009015",
"caption": "The myxoid areas in the low-grade fibromyxoid sarcoma look different from the fibrous areas.",
"image_path": "QDb68_G1HR4_image_2a177f89-5009-48b9-8374-922dce4c7ba5.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " kind of rounded or triangle shaped but even still we really just don't see anything that looks like marked atypia or pleomorphism which is distinctly different from myxofibrosarcoma which again I have another video about that I'll put a link in the video description and up in the upper right hand corner. Myxofibrosarcomas are by definition pleomorphic sarcomas, they're aneuploid, they do not have translocations, they have random gains and losses and thus they have pleomorphism. So even in the grade 1, the low grade form of myxofibrosarcoma, you have to have pleomorphism, that's a different tumor than this low grade fibromyxoid sarcoma or Evans tumor which usually does not have pleomorphism, okay? So the myxoid areas here look a little different than the fibrous areas. So I'm",
"corrected_text": " kind of rounded or triangle shaped but even still we really just don't see anything that looks like marked atypia or pleomorphism which is distinctly different from myxofibrosarcoma which again I have another video about that I'll put a link in the video description and up in the upper right hand corner. myxofibrosarcoma are by definition pleomorphic sarcomas, they're aneuploid, they do not have translocations, they have random gains and losses and thus they have pleomorphism. So even in the grade 1, the low grade form of myxofibrosarcoma, you have to have pleomorphism, that's a different tumor than this low grade fibromyxoid sarcoma or Evans tumor which usually does not have pleomorphism, okay? So the myxoid areas here look a little different than the fibrous areas. So I'm",
"med_umls_ids": "[[{'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'Evans tumor', 'concept_id': 'C2697858', 'confidence': 0.6359843015670776}, {'entity': 'pleomorphism', 'concept_id': 'C0032219', 'confidence': 1.0}, {'entity': 'myxofibrosarcoma', 'concept_id': 'C3714524', 'confidence': 1.0}], [{'entity': 'Myxofibrosarcoma', 'concept_id': 'C3714524', 'confidence': 1.0}, {'entity': 'pleomorphic sarcoma', 'concept_id': 'C1261358', 'confidence': 0.9260651469230652}, {'entity': 'aneuploidy', 'concept_id': 'C0002938', 'confidence': 1.0}, {'entity': 'random', 'concept_id': 'C0034656', 'confidence': 1.0}, {'entity': 'gains', 'concept_id': 'C1517378', 'confidence': 0.7974324226379395}, {'entity': 'losses', 'concept_id': 'C0018840', 'confidence': 0.786555290222168}], [{'entity': 'myxoid areas', 'concept_id': 'C0205295', 'confidence': 0.8464413285255432}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'fibrous areas', 'concept_id': 'C0439709', 'confidence': 0.783623218536377}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_536",
"caption_rating": "8"
},
{
"": "1004916",
"caption": "Discussion of interstitial inflammation and possible diagnoses, including Wells syndrome and hypereosinophilic syndrome.",
"image_path": "udoW6VSqsm4_image_a1b6e813-bf95-44a8-8556-60f1199ad5d4.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " Mostly interstitial. Well, what I thought of with this, because of all of the degranulation, was Wells syndrome. What's the other name for Wells syndrome? Eosinophilic cellulitis. Okay, so what's another couple of conditions that give you mostly interstitial involvement other than Wells? Maybe like a hyper-eosinophilic syndrome? Well, not really. So this interstitial. Interstitial mostly inflammation. It's a different question than what's the diagnosis. Yeah, this is Wells. You got that part right. But you want to figure out some other things that when the board examination sticks some other questions down there, you're not going to say, hmm, it might be that.",
"corrected_text": " Mostly interstitial. Well, what I thought of with this, because of all of the degranulation, was Wells syndrome. What's the other name for Wells syndrome? Eosinophilic cellulitis. Okay, so what's another couple of conditions that give you mostly interstitial involvement other than Wells? Maybe like a hypereosinophilic syndrome? Well, not really. So this interstitial. Interstitial mostly inflammation. It's a different question than what's the diagnosis. Yeah, this is Wells. You got that part right. But you want to figure out some other things that when the board examination sticks some other questions down there, you're not going to say, hmm, it might be that.",
"med_umls_ids": "[[{'entity': 'interstitial inflammation', 'concept_id': 'C1265831', 'confidence': 1.0}, {'entity': 'diagnoses', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'Wells syndrome', 'concept_id': 'C0343101', 'confidence': 1.0}, {'entity': 'hypereosinophilic syndrome', 'concept_id': 'C0263662', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_537",
"caption_rating": "8"
},
{
"": "1009269",
"caption": "The tumor is a histologic mimic of perineurioma and low-grade fibromyxoid sarcoma.",
"image_path": "QDb68_G1HR4_image_e32c5434-c6dd-42c1-9c99-053fb810a06d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " that's why this tumor one of the mimics that you can see one of the histologic mimics is perineurioma and I have another video about perineurioma that really goes into detail. Perineuriomas often have cells that look very much like this and both perineurioma as well as low-grade fibromyxoid sarcoma can have very whirled or swirled areas. This one's not really showing that but some of them do, they have a lot of whirling pattern. So the two other things that keep in the differential here are perineurioma and also dermatofibrosarcoma protuberans, DFSP,",
"corrected_text": " that's why this tumor one of the mimics that you can see one of the histologic mimics is perineurioma and I have another video about perineurioma that really goes into detail. Perineuriomas often have cells that look very much like this and both perineurioma as well as low-grade fibromyxoid sarcoma can have very whirled or swirled areas. This one's not really showing that but some of them do, they have a lot of whirling pattern. So the two other things that keep in the differential here are perineurioma and also dermatofibrosarcoma protuberans, DFSP,",
"med_umls_ids": "[[{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'histologic', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'perineurioma', 'concept_id': 'C0751691', 'confidence': 0.9999999403953552}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}], [{'entity': 'Perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcomas', 'concept_id': 'C1275282', 'confidence': 0.8123146891593933}, {'entity': 'whirled', 'concept_id': 'C1424217', 'confidence': 0.6834293007850647}, {'entity': 'swirled areas', 'concept_id': 'C1968905', 'confidence': 0.5657616853713989}], [{'entity': 'Dermatofibrosarcoma', 'concept_id': 'C0206647', 'confidence': 1.0}, {'entity': 'differential diagnosis', 'concept_id': 'C0011906', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_538",
"caption_rating": "8"
},
{
"": "1007305",
"caption": "Identification of vein or artery based on elastic tissue strain.",
"image_path": "r7OA0Trj5hQ_image_13da7322-e4b8-4a3d-8db9-cba386461840.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " In high power, you can see very thick vessel wall with the narrowing of the lumen, whereas here, it is relatively preserved. So you want to know whether it is a vein or artery. Please believe me, this is a vein, and this is an artery. And that is proved by the elastic tissue strain. These are all pictures from Dr. Gonzalez's Twitter. And you can see here, there is no internal elastic lamina, whereas here, there is an internal elastic lamina. So this is a branch of mesenteric artery, whereas this is a branch of mesenteric vein. And there is a condition called as idiopathic myointimal hyperplasia of the mesenteric vein. I don't know how many of you have heard this company. There's a",
"corrected_text": " In high power, you can see very thick vessel wall with the narrowing of the lumen, whereas here, it is relatively preserved. So you want to know whether it is a vein or artery. Please believe me, this is a vein, and this is an artery. And that is proved by the elastic tissue strain. These are all pictures from Dr. Gonzalez's Twitter. And you can see here, there is no internal elastic lamina, whereas here, there is an internal elastic lamina. So this is a branch of mesenteric artery, whereas this is a branch of mesenteric vein. And there is a condition called as idiopathic myointimal hyperplasia of mesenteric vein of the mesenteric vein. I don't know how many of you have heard this company. There's a",
"med_umls_ids": "[[{'entity': 'Thick vessel wall', 'concept_id': 'C1180033', 'confidence': 0.6420797109603882}, {'entity': 'lumen', 'concept_id': 'C0524461', 'confidence': 0.9999998807907104}, {'entity': 'power', 'concept_id': 'C0032863', 'confidence': 1.0}], [{'entity': 'Identification', 'concept_id': 'C0020792', 'confidence': 1.0}, {'entity': 'vein', 'concept_id': 'C0042449', 'confidence': 1.0}, {'entity': 'artery', 'concept_id': 'C0003842', 'confidence': 1.0}, {'entity': 'elastic tissue', 'concept_id': 'C0013762', 'confidence': 1.0}, {'entity': 'strain', 'concept_id': 'C0080194', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'internal elastic lamina', 'concept_id': 'C1180561', 'confidence': 1.0}, {'entity': 'artery', 'concept_id': 'C0003842', 'confidence': 1.0}, {'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'vein', 'concept_id': 'C0042449', 'confidence': 1.0}], [{'entity': 'Branches', 'concept_id': 'C1182977', 'confidence': 0.7288598418235779}, {'entity': 'mesenteric artery', 'concept_id': 'C0025465', 'confidence': 1.0}, {'entity': 'vein', 'concept_id': 'C0042449', 'confidence': 1.0}, {'entity': 'examples', 'concept_id': 'C1707959', 'confidence': 0.8639216423034668}], [{'entity': 'Idiopathic myointimal hyperplasia', 'concept_id': 'C0333978', 'confidence': 0.8139097094535828}, {'entity': 'mesenteric vein', 'concept_id': 'C0025473', 'confidence': 1.0}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_539",
"caption_rating": "7"
},
{
"": "1006827",
"caption": "The cells being observed are likely nevus cells or melanocytes, which are showing regression and have vesicular nuclei.",
"image_path": "zhzJ9pgCvuw_image_9b37fead-13ef-4620-bd53-a99d29e3039f.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Hematopathology']",
"roi_text": "['Nevus cells or melanocytes with vesicular nuclei.']",
"noisy_text": " yes it is this is this is exactly oh that's a good term we'll say that there's reverse maturation the the nuclei are are not showing any it in a banal nevus if this was a banal nevus at the top you'd have type a nevus cells down at the bottom if this was a nevus in an old portion you'd probably have type c nevus cells where they look neural and they'd at least be type b where there'd be hyperchromatic nuclei and no cytoplasm but these these nevus cells or these melanocytes are vesicular that you like they're type a cells uh so you add all that",
"corrected_text": " yes it is this is this is exactly oh that's a good term we'll say that there's regression the the nuclei are are not showing any it in a banal nevus if this was a banal nevus at the top you'd have type a nevus cells down at the bottom if this was a nevus in an old portion you'd probably have type c nevus cells where they look neural and they'd at least be type b where there'd be hyperchromatic nuclei and no cytoplasm but these these nevus cells or these melanocytes are vesicular that you like they're type a cells uh so you add all that",
"med_umls_ids": "[[{'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'observed', 'concept_id': 'C1441672', 'confidence': 1.0}, {'entity': 'nevus cells', 'concept_id': 'C1142274', 'confidence': 1.0}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'regression', 'concept_id': 'C0684320', 'confidence': 0.9999999403953552}, {'entity': 'vesicular nuclei', 'concept_id': 'C2325471', 'confidence': 0.7651268839836121}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_540",
"caption_rating": "8"
},
{
"": "1009476",
"caption": "Glut-1 is usually negative in perineuriomas, but there are rare reports of positive staining in low-grade fibromyxoid sarcomas.",
"image_path": "QDb68_G1HR4_image_1e4ca39c-40f6-492b-b7c7-c8e20bfaf5f5.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Deep soft tissue', 'Perineurioma', 'Low-grade fibromyxoid sarcoma', 'Immunohistochemistry', 'Swirling growth']",
"noisy_text": " involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is more of a difficult problem because perineurioma has a lot of overlap histologically with low-grade fibromyxoid sarcoma and also immunohistochemically. On immunostains, EMA, Clodin-1 and Glut-1 are three immunostains that will usually stain perineuriomas. The problem is that low-grade fibromyxoid sarcomas often express at least focal EMA, so that's a problem and additionally, the examples of low-grade fibromyxoid sarcoma that have dramatic swirling and whirling growth, those are the ones that have a perineurioma like pattern, the ones that mimic perineurioma. They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The",
"corrected_text": " involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is more of a difficult problem because perineurioma has a lot of overlap histologically with low-grade fibromyxoid sarcoma and also immunohistochemically. On immunostains, EMA, Clodin-1 and Glut-1 are three immunostains that will usually stain perineuriomas. The problem is that low-grade fibromyxoid sarcomas often express at least focal EMA, so that's a problem and additionally, the examples of low-grade fibromyxoid sarcoma that have dramatic swirling and whirling growth, those are the ones that have a perineurioma like pattern, the ones that mimic perineurioma. They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The",
"med_umls_ids": "[[{'entity': 'CD34', 'concept_id': 'C0054953', 'confidence': 1.0}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'deep soft tissue tumors', 'concept_id': 'C0037579', 'confidence': 0.8622524738311768}], [{'entity': 'Perineurioma', 'concept_id': 'C0751691', 'confidence': 0.9999999403953552}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'histologically', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'immunohistochemistry', 'concept_id': 'C0021044', 'confidence': 0.9999998807907104}], [{'entity': 'EMA', 'concept_id': 'C0268596', 'confidence': 0.9999999403953552}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}, {'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'immunohistochemical stains', 'concept_id': 'C4317108', 'confidence': 0.9999999403953552}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibrosarcomas', 'concept_id': 'C0016057', 'confidence': 1.0}, {'entity': 'EMA', 'concept_id': 'C0268596', 'confidence': 0.9999999403953552}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}], [{'entity': 'Low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'swirling', 'concept_id': 'C0233591', 'confidence': 0.7064549922943115}, {'entity': 'growth', 'concept_id': 'C0018270', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'express', 'concept_id': 'C0017262', 'confidence': 0.8176293969154358}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}], [{'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'reports', 'concept_id': 'C0684224', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcomas', 'concept_id': 'C1275282', 'confidence': 0.8123146891593933}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_541",
"caption_rating": "8"
},
{
"": "1004200",
"caption": "A CD34 stain is not necessary for a classic DFSP diagnosis.",
"image_path": "LlPaENuqzVQ_image_76a5b714-55f4-4548-a00f-fcd28a02bf2a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['diffuse pattern between and among lipocytes', 'typical storiform pattern', 'ring chromosome', 'translocation involving collagen A and platelet-derived growth factor', 'diffuse pattern between and among lipocytes']",
"noisy_text": " you can impress your friends and colleagues. You can say, this is DFSB. You don't need the storiform pattern. If you see this, you got the diagnosis. No other neoplasm really gets diffusely between and among lipocytes in a diffuse pattern like this, other than DFSB. Now you look up here and yeah, you do have the nice, beautiful storiform pattern here. And you don't really need a CD34 stain here. You can do it if you want to, if you like to sort of charge patients extra money, but this is a classic DFSB. And that ring chromosome, the collagen A, platelet-derived growth factor, the translocation is classic for that. And one",
"corrected_text": " you can impress your friends and colleagues. You can say, this is DFSP. You don't need the storiform pattern. If you see this, you got the diagnosis. No other neoplasm really gets diffusely between and among lipocytes in a diffuse pattern like this, other than DFSP. Now you look up here and yeah, you do have the nice, typical storiform pattern here. And you don't really need a CD34 stain here. You can do it if you want to, if you like to sort of charge patients extra money, but this is a classic DFSP. And that ring chromosome, the collagen A, platelet-derived growth factor, the translocation is classic for that. And one",
"med_umls_ids": "[[{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'diffuse', 'concept_id': 'C0205219', 'confidence': 1.0}, {'entity': 'lipocytes', 'concept_id': 'C0206131', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}], [{'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}, {'entity': 'storiform pattern', 'concept_id': 'C1336510', 'confidence': 0.8142904043197632}], [{'entity': 'CD34 stain', 'concept_id': 'C0038128', 'confidence': 0.5134490728378296}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'ring chromosome', 'concept_id': 'C0035639', 'confidence': 1.0}, {'entity': 'translocation', 'concept_id': 'C0040715', 'confidence': 1.0}, {'entity': 'collagen A', 'concept_id': 'C0009325', 'confidence': 0.9128584265708923}, {'entity': 'platelet-derived growth factor', 'concept_id': 'C0032200', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_542",
"caption_rating": "8"
},
{
"": "1007570",
"caption": "Muscle bundles are seen in the lamina propria due to hyperplasia of the muscularis mucosa.",
"image_path": "r7OA0Trj5hQ_image_ee9486d9-d74a-4c27-815d-5c02fa6616ac.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['muscle', 'lamina propria', 'muscularis mucosa', 'chemical gastritis', 'mucosal prolapse', 'solitary rectal ulcer syndrome', 'muscle', 'lamina propria', 'muscularis mucosa', 'chemical gastritis', 'mucosal prolapse', 'solitary rectal ulcer syndrome']",
"noisy_text": " You see in the hyperwire, muscle coming in the lamina propria. Lamina propria should be free of musculature. The muscle should be there only in the muscularis mucosa. Here in this low power, you can see the muscularis mucosa is hyperplastic. And it is sending the muscle bundle into the lamina propria. This happens in chemical gastritis in case of stomach and in cases of mucosal prolapse in colon. Remember that solitary rectal ulcer syndrome, which is totally misnomer. It is neither solitary, can be seen in other parts other than rectum. There may not be any ulcer, there is no syndrome. So the whole solitary rectal ulcer syndrome is a misnomer. But muscularization of the lamina propria is one of the criteria for mucosal prolapse that is happening in",
"corrected_text": " You see in the hyperplasia, muscle coming in the lamina propria. Lamina propria should be free of musculature. The muscle should be there only in the muscularis mucosa. Here in this low power, you can see the muscularis mucosa is hyperplastic. And it is sending the muscle bundle into the lamina propria. This happens in chemical gastritis in case of stomach and in cases of mucosal prolapse in colon. Remember that solitary rectal ulcer syndrome, which is totally misnomer. It is neither solitary, can be seen in other parts other than rectum. There may not be any ulcer, there is no syndrome. So the whole solitary rectal ulcer syndrome is a misnomer. But muscularization of the lamina propria is one of the criteria for mucosal prolapse that is happening in",
"med_umls_ids": "[[{'entity': 'Muscle hyperplasia', 'concept_id': 'C2265913', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'abnormal', 'concept_id': 'C0205161', 'confidence': 1.0}, {'entity': 'muscularis mucosa', 'concept_id': 'C0225357', 'confidence': 0.9999998807907104}], [{'entity': 'Muscle bundles', 'concept_id': 'C0504095', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'hyperplasia', 'concept_id': 'C0020507', 'confidence': 1.0}, {'entity': 'muscularis mucosa', 'concept_id': 'C0225357', 'confidence': 0.9999998807907104}], [{'entity': 'Muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'criterion', 'concept_id': 'C0243161', 'confidence': 1.0}, {'entity': 'mucosal prolapse', 'concept_id': 'C0034888', 'confidence': 0.826268196105957}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_543",
"caption_rating": "9"
},
{
"": "1008007",
"caption": "Basal cell carcinoma with sebaceous differentiation should have clefting and palisading with obvious sebaceous differentiation.",
"image_path": "udoW6VSqsm4_image_3a789541-9419-4967-a4d9-8751d3c6c93d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['sebaceoma', 'basal cell carcinoma', 'sebaceous differentiation', 'sebaceoma', 'basal cell carcinoma', 'sebaceous differentiation']",
"noisy_text": " I think we've called it sebaceous epithelium, but again I'm not a big fan of that term. And these look usually like this. They're usually small, round, skin-colored leaves. They kind of look like sebaceous epithelium. They usually come in as real-life basins, so nobody diagnoses these clinically correctly. So these are items in the differential diagnosis. Basal cell with sebaceous differentiation, if you're going to make that diagnosis, it generally needs to look like a basal cell with nice clefting and put the palisade in there and all that, and then have foci where there's obvious sebaceous differentiation. You'll see that on occasion. But I would probably call this sebaceoma, without thinking it's sort of synonymous with sebaceous epithelium. Now, is there any condition you have to worry about with these? With any",
"corrected_text": " I think we've called it sebaceous epithelium, but again I'm not a big fan of that term. And these look usually like this. They're usually small, round, skin-colored leaves. They kind of look like sebaceous epithelium. They usually come in as real-life basins, so nobody diagnoses these clinically correctly. So these are items in the differential diagnosis. Basal cell with sebaceous differentiation, if you're going to make that diagnosis, it generally needs to look like a basal cell with nice clefting and put the palisade in there and all that, and then have foci where there's obvious sebaceous differentiation. You'll see that on occasion. But I would probably call this sebaceoma, without thinking it's sort of synonymous with sebaceous epithelium. Now, is there any condition you have to worry about with these? With any",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'sebaceoma', 'concept_id': 'C1275210', 'confidence': 1.0}, {'entity': 'basal cell carcinoma', 'concept_id': 'C0007117', 'confidence': 1.0}, {'entity': 'sebaceous differentiation', 'concept_id': 'C1882988', 'confidence': 1.0}], [{'entity': 'Sebaceomas', 'concept_id': 'C1275210', 'confidence': 0.8855459690093994}, {'entity': 'small', 'concept_id': 'C0700321', 'confidence': 0.9999998807907104}, {'entity': 'round', 'concept_id': 'C0332490', 'confidence': 1.0}, {'entity': 'skin-colored', 'concept_id': 'C4476819', 'confidence': 0.8005288243293762}], [{'entity': 'Basal cell carcinoma', 'concept_id': 'C0007117', 'confidence': 1.0}, {'entity': 'sebaceous differentiation', 'concept_id': 'C1882988', 'confidence': 1.0}, {'entity': 'clefting', 'concept_id': 'C4021813', 'confidence': 0.8906428217887878}, {'entity': 'palisading', 'concept_id': 'C1622240', 'confidence': 0.8684062361717224}, {'entity': 'sebaceous differentiation', 'concept_id': 'C1882988', 'confidence': 1.0}], [{'entity': 'conditions', 'concept_id': 'C0012634', 'confidence': 0.8556983470916748}, {'entity': 'concern', 'concept_id': 'C2699424', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_544",
"caption_rating": "8"
},
{
"": "1005777",
"caption": "A small subset of cases (around 10%) may have areas with increased cellularity, scattered pleomorphism, a round cell or epithelioid cell appearance.",
"image_path": "QDb68_G1HR4_image_b06fa2cd-0137-4098-a925-6354fb23cc07.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " Now I've been telling you and highlighting how important it is to know that these tumors don't have atypia. Now again that's another rule that's sometimes broken I think it's important to learn that the most common the most common appearance is a benign looking tumor that doesn't look atypical that's important because I think that's the one those are the ones that are easy to miss but it is worth noting that a subset a small subset maybe around 10% of cases can have areas with increased cellularity, scattered pleomorphism, a round cell or epithelioid cell appearance. There have also been rare reports of cases that truly have a full-blown high-grade pleomorphic sarcoma like appearance like that they've transitioned into high-grade sarcoma or I think even osteosarcomatous areas have been described. These are all really rare exceptions to the rule but I and I think it's again much more important for the general pathologists to know that this very bland benign looking appearance because this",
"corrected_text": " Now I've been telling you and highlighting how important it is to know that these tumors don't have atypia. Now again that's another rule that's sometimes broken I think it's important to learn that the most common the most common appearance is a benign looking tumor that doesn't look atypical that's important because I think that's the one those are the ones that are easy to miss but it is worth noting that a subset a small subset maybe around 10% of cases can have areas with increased cellularity, scattered pleomorphism, a round cell or epithelioid cell appearance. There have also been rare reports of cases that truly have a full-blown high-grade pleomorphic sarcoma like appearance like that they've transitioned into high-grade sarcoma or I think even osteosarcomatous areas have been described have been described. These are all really rare exceptions to the rule but I and I think it's again much more important for the general pathologists to know that this very bland benign looking appearance because this",
"med_umls_ids": "[[{'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'benign', 'concept_id': 'C0205183', 'confidence': 1.0}, {'entity': 'atypia', 'concept_id': 'C0741302', 'confidence': 0.9999999403953552}], [{'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'increased', 'concept_id': 'C0205217', 'confidence': 1.0}, {'entity': 'cellularity', 'concept_id': 'C0178539', 'confidence': 0.9999999403953552}, {'entity': 'scattered', 'concept_id': 'C0439742', 'confidence': 1.0}, {'entity': 'pleomorphism', 'concept_id': 'C0032219', 'confidence': 1.0}, {'entity': 'round cell', 'concept_id': 'C0487470', 'confidence': 1.0}, {'entity': 'epithelioid cell', 'concept_id': 'C0014603', 'confidence': 0.9999999403953552}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}], [{'entity': 'Rare', 'concept_id': 'C0521114', 'confidence': 1.0}, {'entity': 'reports', 'concept_id': 'C0684224', 'confidence': 1.0}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'high-grade', 'concept_id': 'C1512433', 'confidence': 0.9347730875015259}, {'entity': 'pleomorphic', 'concept_id': 'C1514164', 'confidence': 1.0}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'osteosarcomatous areas', 'concept_id': 'C0279602', 'confidence': 0.7822340130805969}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_545",
"caption_rating": "8"
},
{
"": "1005628",
"caption": "The size of the particles within the histiocytes is markedly variable.",
"image_path": "8S4LeiO6Bbk_image_86c69d80-19b3-425b-a70b-4ffd6a5700ff.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Pigmented histiocytes with hemocyanin pigment', 'Extravasated erythrocytes', 'Size of particles within histiocytes', 'Pigmented histiocytes with hemocyanin pigment', 'Extravasated erythrocytes', 'Size of particles within histiocytes']",
"noisy_text": " in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes as suspected is hemocentaurant. If you notice, it's got kind of that golden brown color. If you had a sub-stage condenser or a fine focus knob, you would see that it's somewhat refractile, but unfortunately, we can't use that particular tool when we're looking at scanned images. But one clue to the fact that we're dealing with hemocentaurant rather than melanin, not only is the presence of extravasated erythrocytes, but if you look at the size of the particles within the histiocytes, they're markedly variable. So the hemocentaurant is of course a breakdown product of the RBCs. And you can see that we've got small granules next to very large, chunky granules. Melanin pigment on the other hand, which of course can be found in melanophages or histiocytes containing the particles, the melanin granules tend to be more uniform in size. And of course, one can always do special stains, an iron stain, such as Prussian blue or pearls for hemocentaurant and a Fontanumus song stain for melanin pigment. So in any case, getting back to the to the lesion in question, we've got a lot of hemocentaurant-laden histiocytes here. We've also got, in other areas, fascicles, kind of randomly oriented of histiocytes and fibrocytes with oval",
"corrected_text": " in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes as suspected is hemocyanin. If you notice, it's got kind of that golden brown color. If you had a sub-stage condenser or a fine focus knob, you would see that it's somewhat refractile, but unfortunately, we can't use that particular tool when we're looking at scanned images. But one clue to the fact that we're dealing with hemocyanin rather than melanin, not only is the presence of extravasated erythrocytes, but if you look at the size of the particles within the histiocytes, they're markedly variable. So the hemocyanin is of course a breakdown product of the RBCs. And you can see that we've got small granules next to very large, chunky granules. Melanin pigment on the other hand, which of course can be found in melanophages or histiocytes containing the particles, the melanin granules tend to be more uniform in size. And of course, one can always do special stains, an iron stain, such as Prussian blue or pearls for hemocyanin and a Fontana-Masson stain for melanin pigment. So in any case, getting back to the to the lesion in question, we've got a lot of hemocyanin-laden histiocytes here. We've also got, in other areas, fascicles, kind of randomly oriented of histiocytes and fibrocytes with oval",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'pigment', 'concept_id': 'C0031911', 'confidence': 1.0}, {'entity': 'breakdown', 'concept_id': 'C0699900', 'confidence': 0.9999999403953552}, {'entity': 'product', 'concept_id': 'C1254351', 'confidence': 1.0}, {'entity': 'RBCs', 'concept_id': 'C0014792', 'confidence': 1.0}], [{'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'particles', 'concept_id': 'C0597177', 'confidence': 1.0}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'variable', 'concept_id': 'C0439828', 'confidence': 1.0}], [{'entity': 'Melanin', 'concept_id': 'C0025196', 'confidence': 1.0}, {'entity': 'pigment', 'concept_id': 'C0031911', 'confidence': 1.0}, {'entity': 'uniform', 'concept_id': 'C0205375', 'confidence': 1.0}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}], [{'entity': 'Special stains', 'concept_id': 'C0038128', 'confidence': 0.7105166912078857}, {'entity': 'Prussian blue', 'concept_id': 'C0060234', 'confidence': 1.0}, {'entity': 'Fontana-Masson', 'concept_id': 'C0060631', 'confidence': 0.9090515375137329}, {'entity': 'confirm', 'concept_id': 'C0521093', 'confidence': 1.0}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}, {'entity': 'pigment', 'concept_id': 'C0031911', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_546",
"caption_rating": "8"
},
{
"": "1009480",
"caption": "Hemocyanin is present within the histiocytes.",
"image_path": "8S4LeiO6Bbk_image_27c0dd24-eb37-496d-b955-579d7c5d1027.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['lipid vacuoles', 'multinucleated histiocytes', 'ringed siderophages', 'pigmented histiocytes', 'hemocyanin', 'lipid vacuoles', 'multinucleated histiocytes', 'ringed siderophages', 'pigmented histiocytes', 'hemocyanin', 'lipid vacuoles', 'multinucleated histiocytes', 'ringed siderophages', 'pigmented histiocytes', 'hemocyanin']",
"noisy_text": " large histiocytes containing lipid. Some of them are multi-nucleated and some of these are actually ringed siderophages. So we see large multi-nucleated histiocytes with a ring of nuclei and they contain not only lipid vacuoles but hemocentaurant. And these are particularly common in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes as suspected is hemocentaurant. If you notice, it's got kind of that golden brown color. If you had a sub-stage condenser or a fine focus knob, you would see that it's somewhat refractile, but unfortunately, we can't use that particular tool when we're looking at scanned images.",
"corrected_text": " large histiocytes containing lipid. Some of them are multinucleated and some of these are actually ringed siderophages. So we see large multinucleated histiocytes with a ring of nuclei and they contain not only lipid vacuoles but hemosiderin. And these are particularly common in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes as suspected is hemosiderin. If you notice, it's got kind of that golden brown color. If you had a sub-stage condenser or a fine focus knob, you would see that it's somewhat refractile, but unfortunately, we can't use that particular tool when we're looking at scanned images.",
"med_umls_ids": "[[{'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'lipid', 'concept_id': 'C0023779', 'confidence': 1.0}, {'entity': 'multinucleated', 'concept_id': 'C0333740', 'confidence': 1.0}, {'entity': 'ringed', 'concept_id': 'C0325501', 'confidence': 0.77345871925354}, {'entity': 'siderophages', 'concept_id': 'C1136253', 'confidence': 0.7251443266868591}], [{'entity': 'Hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}], [{'entity': 'Pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_547",
"caption_rating": "8"
},
{
"": "1007969",
"caption": "The process is infiltrating between benign glands and respecting them, which is a clue to the diagnosis.",
"image_path": "iklRyY1nBIE_image_25025022-8442-4585-8463-496487442b19.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['basal cell hyperplasia', 'infiltrating between benign glands', 'STOMP', 'prostatic stroma of sarcoma', 'HMB45 melanin', 'S100', 'STAT6']",
"noisy_text": " Something else you may have observed with this case is the fact that it's not just a stroma process. It looks like there's something else going on in the glands, too. And in the glands, it's almost like there's a crosstalk between the stroma process and the glands. The glands are benign, but they actually have what looks like basal cell hyperplasia in areas. And that's not uncommon with this entity. It is not unusual to have this entity, actually, with basal cell hyperplasia. The other observation I want to bring to your attention is the fact that this process is going in between benign glands, which means that it's almost respecting the benign glands next door. Because there are a number of processes that would destroy the adjacent benign glands and basically push them aside. But this process actually respects the benign glands, in quotes, and is actually going in between them, infiltrating in between them. And that's a clue to the diagnosis. Because as I hinted earlier, when you talk of tumors of the specialized prosthetic stroma, there are two main entities you think about. One is the so-called STOMP, stromal tumor of unsaturated malignant potential. And the other entity at the other extreme is the so-called prosthetic stroma of sarcoma. Some argue that there's some relationship between both of them that are in the spectrum. But what you're looking at right now in this case, based on what I've shown you, this type of atypia, it almost looks simplistic. It has this degenerative type of look to it. We are not seeing mitotic activity. For something this ugly or that looks this nasty, you'll expect to see necrosis, mitotic activity, and even destruction of the adjacent glands. But we're not seeing that. And that's kind of a perfect picture for so-called STOMP, stromal tumor of unsaturated malignant potential. As I said earlier, there's a relationship between this entity and prosthetic stroma of sarcoma. To start with, STOMPs can recur. About 15% of STOMPs can recur months or years after the initial resection. But about 15% to 20% of STOMPs may progress or may be associated with adjacent prosthetic stroma of sarcoma. So that's a very important thing to know. Because STOMP itself, as the name implies, is of unsaturated malignant potential. So it should not be downplayed. Because some of you may ask me, how do I sign all these cases? It's very important in your comments to document what I just said, that about 15% of these, if it's just STOMP is here on the H&E, nothing else, it's important to document that about 15% would recur. And more importantly, it's important to document that about 15% to 20% of these may be associated with or progress to prosthetic stroma of sarcoma. So it's not a case of they excise this and they leave the patient alone. They need to follow up these patients very closely. So that's very important to document in the report. So some of you may ask, OK, so what stains do we do for these cases? Obviously, you want to exclude a number of things. We talked about melanoma and other things. So you want to exclude those. So obviously, HMB45 melanin, those will be negative. Vimentin, which nobody uses anymore, is actually positive in this entity. PR could also be positive in this entity. Plus or minus CD34, plus or minus Desmin SMA, plus or minus ER may be positive, but it's usually negative. The pertinent negative stains are S100. I talked about the melanoma markers. And STAT6 is also negative. So it's very important to know that. So this is a stromal tumor of uncertain malignant potential. There have been a number of names for this entity over the years.",
"corrected_text": " Something else you may have observed with this case is the fact that it's not just a stroma process. It looks like there's something else going on in the glands, too. And in the glands, it's almost like there's a crosstalk between the stroma process and the glands. The glands are benign, but they actually have what looks like basal cell hyperplasia in areas. And that's not uncommon with this entity. It is not unusual to have this entity, actually, with basal cell hyperplasia. The other observation I want to bring to your attention is the fact that this process is going in between benign glands, which means that it's almost respecting the benign glands next door. Because there are a number of processes that would destroy the adjacent benign glands and basically push them aside. But this process actually respects the benign glands, in quotes, and is actually going in between them, infiltrating in between them. And that's a clue to the diagnosis. Because as I hinted earlier, when you talk of tumors of the specialized prosthetic stroma, there are two main entities you think about. One is the so-called STOMP, stromal tumor of unsaturated malignant potential. And the other entity at the other extreme is the so-called prosthetic stroma of sarcoma. Some argue that there's some relationship between both of them that are in the spectrum. But what you're looking at right now in this case, based on what I've shown you, this type of atypia, it almost looks simplistic. It has this degenerative type of look to it. We are not seeing mitotic activity. For something this ugly or that looks this nasty, you'expect to see necrosis, mitotic activity, and even destruction of the adjacent glands. But we're not seeing that. And that's kind of a perfect picture for so-called STOMP, stromal tumor of unsaturated malignant potential. As I said earlier, there's a relationship between this entity and prosthetic stroma of sarcoma. To start with, STOMPs can recur. About 15% of STOMPs can recur months or years after the initial resection. But about 15% to 20% of STOMPs may progress or may be associated with adjacent prosthetic stroma of sarcoma. So that's a very important thing to know. Because STOMP itself, as the name implies, is of unsaturated malignant potential. So it should not be downplayed. Because some of you may ask me, how do I sign all these cases? It's very important in your comments to document what I just said, that about 15% of these, if it's just STOMP is here on the H&E, nothing else, it's important to document that about 15% would recur. And more importantly, it's important to document that about 15% to 20% of these may be associated with or progress to prosthetic stroma of sarcoma. So it's not a case of they excise this and they leave the patient alone. They need to follow up these patients very closely. So that's very important to document in the report. So some of you may ask, OK, so what stains do we do for these cases? Obviously, you want to exclude a number of things. We talked about melanoma and other things. So you want to exclude those. So obviously, HMB45 melanin, those will be negative. Vimentin, which nobody uses anymore, is actually positive in this entity. PR could also be positive in this entity. Plus or minus CD34, plus or minus Desmin SMA, plus or minus ER may be positive, but it's usually negative. The pertinent negative stains are S100. I talked about the melanoma markers. And STAT6 is also negative. So it's very important to know that. So this is a stromal tumor of uncertain malignant potential. There have been a number of names for this entity over the years.",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'basal cell', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'benign glands', 'concept_id': 'C1301287', 'confidence': 0.726940393447876}, {'entity': 'entity', 'concept_id': 'C1551338', 'confidence': 1.0}], [{'entity': 'process', 'concept_id': 'C1184743', 'confidence': 1.0}, {'entity': 'infiltrating', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'benign glands', 'concept_id': 'C1301287', 'confidence': 0.726940393447876}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'atypia', 'concept_id': 'C0741302', 'confidence': 0.9999999403953552}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'consistent with', 'concept_id': 'C0332290', 'confidence': 1.0}, {'entity': 'STOMP', 'concept_id': 'C0056167', 'confidence': 0.6245664358139038}, {'entity': 'stromal tumor', 'concept_id': 'C0879615', 'confidence': 1.0}, {'entity': 'malignant', 'concept_id': 'C0205282', 'confidence': 1.0}, {'entity': 'potential', 'concept_id': 'C3245505', 'confidence': 1.0}], [{'entity': 'STOMPs', 'concept_id': 'C0577018', 'confidence': 0.6140404343605042}, {'entity': 'recur', 'concept_id': 'C0034897', 'confidence': 0.9999999403953552}, {'entity': 'progress', 'concept_id': 'C1272688', 'confidence': 1.0}, {'entity': 'prostatic stroma', 'concept_id': 'C1521760', 'confidence': 0.9999999403953552}, {'entity': 'sarcoma', 'concept_id': 'C1261473', 'confidence': 1.0}], [{'entity': 'Stains', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'entities', 'concept_id': 'C0424215', 'confidence': 0.7521668672561646}, {'entity': 'HMB45', 'concept_id': 'C1440756', 'confidence': 1.0}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}, {'entity': 'S100', 'concept_id': 'C3273837', 'confidence': 1.0}, {'entity': 'STAT6', 'concept_id': 'C0297890', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_548",
"caption_rating": "8"
},
{
"": "1005321",
"caption": "Presence of nuclear and cytoplasmic inclusion indicating CMV infection which affects mesenchymal derived cells first, endothelial cells and fibroblasts leading to vasculitis and ischemia.",
"image_path": "r7OA0Trj5hQ_image_e2e8ea2e-d7e1-43d2-b645-27fe3e63b561.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['endothelial cells', 'vasculitis and ischemia', 'endothelial cells', 'vasculitis and ischemia']",
"noisy_text": " nuclear and cytoplasmic inclusion. These are CMV infection. These are all involving blood vessels. One thing for CMV, it affects mesenchymal derived cells first, endothelial cells and the fibroblasts. Since it's involving the endothelial cells, it produces vasculitis and ischemia. And that's why most of the CMV gastroenteropathy is associated with ischemic changes because of the overlapping vasculitis. Here, it is involving more epithelium. Whereas here, it's involving more endothelium. This is a special strain, gastric biopsy again. You see",
"corrected_text": " nuclear and cytoplasmic inclusion. These are CMV infection. These are all involving blood vessels. One thing for CMV, it affects mesenchymal derived cells first, endothelial cells and the fibroblasts. Since it's involving the endothelial cells, it produces vasculitis and ischemia. And that's why most of the CMV gastroenteropathy is associated with ischemic changes because of the overlapping vasculitis. Here, it is involving more epithelium. Whereas here, it's involving more endothelium. This is a special strain, gastric biopsy again. You see",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'nuclear', 'concept_id': 'C0521447', 'confidence': 1.0}, {'entity': 'cytoplasmic', 'concept_id': 'C0010834', 'confidence': 1.0}, {'entity': 'inclusion', 'concept_id': 'C0007637', 'confidence': 1.0}, {'entity': 'CMV infection', 'concept_id': 'C0010823', 'confidence': 1.0}, {'entity': 'mesenchymal', 'concept_id': 'C1513143', 'confidence': 1.0}, {'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'endothelial cells', 'concept_id': 'C0225336', 'confidence': 1.0}, {'entity': 'fibroblasts', 'concept_id': 'C0016030', 'confidence': 1.0}, {'entity': 'vasculitis', 'concept_id': 'C0042384', 'confidence': 1.0}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_549",
"caption_rating": "10"
},
{
"": "1008558",
"caption": "Histopathological description of proliferative cells with ATP and hyperplastic glands.",
"image_path": "r7OA0Trj5hQ_image_c3ffa8b2-387b-4d35-b219-84a9f742c5d7.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Loss of mucin', 'Loss of cellular polarity', 'Nuclear stratification', 'Mitosis', 'Apoptosis', 'Loss of mucin', 'Loss of cellular polarity', 'Nuclear stratification', 'Mitosis', 'Apoptosis']",
"noisy_text": " This is proliferative. With ATP or without ATP? With ATP? With invasion or without invasion? In this field, we cannot judge the invasion. So this is a proliferation with ATP. And see the glands stratify. And loss of mucin or less of mucin. And there is loss of polarity. Look at this nuclei running like in this direction. Look at this nuclei running in this direction. So clearly, loss of polarity. And the nuclear stratification is reaching the top of the epithelium, marked apoptosis. It's too thick to see the mitosis, but here you can see the mitosis. So this is stratification, loss of mucin, mitosis, apoptosis. So this",
"corrected_text": " This is proliferative. With ATP or without ATP? With ATP? With invasion or without invasion? In this field, we cannot judge the invasion. So this is a proliferation with ATP. And see the glands stratify. And loss of mucin or less of mucin. And there is loss of polarity. Look at this nuclei running like in this direction. Look at this nuclei running in this direction. So clearly, loss of polarity. And the nuclear stratification is reaching the top of the epithelium, marked apoptosis. It's too thick to see the mitosis, but here you can see the mitosis. So this is stratification, loss of mucin, mitosis, apoptosis. So this",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'proliferative cells', 'concept_id': 'C0334094', 'confidence': 0.8005025386810303}, {'entity': 'ATP', 'concept_id': 'C0001480', 'confidence': 1.0}, {'entity': 'hyperplastic glands', 'concept_id': 'C0020507', 'confidence': 0.7789753675460815}], [{'entity': 'Loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'mucin', 'concept_id': 'C0026682', 'confidence': 1.0}, {'entity': 'cellular polarity', 'concept_id': 'C0085304', 'confidence': 1.0}], [{'entity': 'Nuclear', 'concept_id': 'C0521447', 'confidence': 1.0}, {'entity': 'stratification', 'concept_id': 'C1514983', 'confidence': 1.0}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'apoptosis', 'concept_id': 'C0162638', 'confidence': 1.0}], [{'entity': 'Mitosis', 'concept_id': 'C0026255', 'confidence': 0.9999998807907104}, {'entity': 'stratification', 'concept_id': 'C1514983', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_550",
"caption_rating": "8"
},
{
"": "1007676",
"caption": "Presence of hemosiderin and foamy areas in some regions.",
"image_path": "udoW6VSqsm4_image_268d2681-a524-4a5c-90e3-dcda155aafed.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['hemosiderin areas', 'foamy areas', 'lipid-laden cells', 'cellular dermatofibroma', 'dermatofibroma with large atypical cells', 'dermatofibroma with monster cells']",
"noisy_text": " Like there are areas where there was hemosiderin. It's kind of hard to see from here, but I found some areas where there was hemosiderin, but some areas that were also a little foamy. Yeah, I'd say a little bit foamy. Scale of one to ten, that's probably about a ten with regard to foaming. So yeah, they're very lipidized. So this would be like a cellular dermatofibroma with lipidization. There's another type of dermatofibroma where you can see large atypical cells, or dermatofibroma with monster cells. Those can simulate cancer. This one didn't really have as many of those kinds of cells. Yeah, so",
"corrected_text": " Like there are areas where there was hemosiderin. It's kind of hard to see from here, but I found some areas where there was hemosiderin, but some areas that were also a little foamy. Yeah, I'd say a little bit foamy. Scale of one to ten, that's probably about a ten with regard to foaming. So yeah, they're very lipidized cells. So this would be like a cellular dermatofibroma with lipidization of cells. There's another type of dermatofibroma where you can see large atypical cells, or dermatofibroma with monster cells. Those can simulate cancer. This one didn't really have as many of those kinds of cells. Yeah, so",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'hemosiderin', 'concept_id': 'C0019113', 'confidence': 1.0}, {'entity': 'foamy', 'concept_id': 'C4523940', 'confidence': 0.8298001885414124}, {'entity': 'regions', 'concept_id': 'C0242961', 'confidence': 0.8140352964401245}], [{'entity': 'Cellular dermatofibroma', 'concept_id': 'C0002991', 'confidence': 0.833601713180542}, {'entity': 'lipid accumulation', 'concept_id': 'C0333574', 'confidence': 1.0}], [{'entity': 'dermatofibroma', 'concept_id': 'C0002991', 'confidence': 1.0}, {'entity': 'atypical cells', 'concept_id': 'C0333865', 'confidence': 1.0}, {'entity': 'monster cells', 'concept_id': 'C0007584', 'confidence': 0.7091032862663269}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_551",
"caption_rating": "7"
},
{
"": "1007183",
"caption": "One gland has early corpora and mucin formation, while another is more atrophic.",
"image_path": "iklRyY1nBIE_image_1521bb4e-c5c0-4abb-9e9e-9ba6e9a39567.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['fairly well circumscribed gland with early corpora and mucin formation', 'more atrophic gland', 'fairly well circumscribed gland with early corpora and mucin formation', 'more atrophic gland']",
"noisy_text": " The problem is the previous case I showed you actually had sharp luminal borders, even though it was partial atrophy. So that's what makes this tricky. But in this case, you can see the fairly well circumscribed, one of the glands even has a little bit of early corpora and malatial formation. But you also have this gland over here that looks somewhat similar, but a little bit more atrophic. And if you look at the corresponding immunosuchemical stain and that focus of interest, we'll see what happens. So again, this was a pink cocktail. In this",
"corrected_text": " The problem is the previous case I showed you actually had sharp luminal borders, even though it was partial atrophy. So that's what makes this tricky. But in this case, you can see the fairly well circumscribed, one of the glands even has a little bit of early corpora and mucin formation. But you also have this gland over here that looks somewhat similar, but a little bit more atrophic. And if you look at the corresponding immunohistochemical stain and that focus of interest, we'll see what happens. So again, this was a pink cocktail. In this",
"med_umls_ids": "[[{'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'luminal borders', 'concept_id': 'C0524462', 'confidence': 0.6706532835960388}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}], [{'entity': 'One gland', 'concept_id': 'C1285092', 'confidence': 0.8090358972549438}, {'entity': 'early', 'concept_id': 'C1279919', 'confidence': 1.0}, {'entity': 'corpora', 'concept_id': 'C4521398', 'confidence': 0.8943701982498169}, {'entity': 'mucin', 'concept_id': 'C0026682', 'confidence': 1.0}, {'entity': 'formation', 'concept_id': 'C0220781', 'confidence': 1.0}, {'entity': 'atrophic', 'concept_id': 'C0151514', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_552",
"caption_rating": "8"
},
{
"": "1008695",
"caption": "Follicular neoplasms commonly have a fibrous stroma, which is helpful in diagnosis.",
"image_path": "LlPaENuqzVQ_image_149214c6-8962-445f-97b4-994109a88c61.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['Trichofolliculoma with a cyst and miniaturized hair follicles', 'fibrous stroma', 'clefting between epithelium and stroma', 'clefting between epithelium and stroma']",
"noisy_text": " This is sort of a tricofolliculoma cut adjacent to the really the central cyst. And the tricofolliculoma has got a little cyst with these little miniaturized hair follicles that are radiating from the central cyst component of the lesion. So this is off to the side of it. But you can see that these follicular neoplasms, they pretty much commonly do have this stroma that you see with it that's more fibrous as opposed to fibromucinous. And that's helpful. It's not a criterion for the diagnosis necessarily every time, but it's a helpful finding when you see it because you don't usually get clefting between the epithelium and the stroma in these lesions as opposed to a basal cell carcinoma where you do. So that's a tricofolliculoma kind of cut to the side. OK, let's",
"corrected_text": " This is sort of a trichofolliculoma cut adjacent to the really the central cyst. And the trichofolliculoma has got a little cyst with these little miniaturized hair follicles that are radiating from the central cyst component of the lesion. So this is off to the side of it. But you can see that these follicular neoplasms, they pretty much commonly do have this stroma that you see with it that's more fibrous as opposed to fibromyxoid. And that's helpful. It's not a criterion for the diagnosis necessarily every time, but it's a helpful finding when you see it because you don't usually get clefting between the epithelium and the stroma in these lesions as opposed to a basal cell carcinoma where you do. So that's a trichofolliculoma kind of cut to the side. OK, let's",
"med_umls_ids": "[[{'entity': 'Trichofolliculoma', 'concept_id': 'C0334262', 'confidence': 1.0}, {'entity': 'cyst', 'concept_id': 'C0010709', 'confidence': 1.0}, {'entity': 'miniaturized hair follicles', 'concept_id': 'C0221971', 'confidence': 0.7287319302558899}, {'entity': 'adjacent', 'concept_id': 'C0205117', 'confidence': 1.0}, {'entity': 'central cyst', 'concept_id': 'C0205099', 'confidence': 0.7124271988868713}], [{'entity': 'Follicular', 'concept_id': 'C0439682', 'confidence': 1.0}, {'entity': 'neoplasms', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'fibrous stroma', 'concept_id': 'C1180207', 'confidence': 0.8035051226615906}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'Clefting', 'concept_id': 'C4021813', 'confidence': 0.8906428217887878}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'stroma', 'concept_id': 'C0927195', 'confidence': 1.0}, {'entity': 'lesions', 'concept_id': 'C0221198', 'confidence': 1.0}, {'entity': 'basal cell carcinoma', 'concept_id': 'C0007117', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_553",
"caption_rating": "8"
},
{
"": "1006570",
"caption": "The tissue has myxoid features with very fine delicate collagen.",
"image_path": "QDb68_G1HR4_image_9663f836-2793-4daf-9f55-9b76c5b0cf75.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['myxoid features', 'fine delicate collagen', 'cellular intramuscular myxoma', 'fibrous areas', 'cellular areas', 'MUC4 stain', 'myxoid features', 'fine delicate collagen', 'cellular intramuscular myxoma', 'fibrous areas', 'cellular areas', 'MUC4 stain']",
"noisy_text": " Here's again the myxoid background I really think this is very helpful. The very very fine delicate collagen that you see. Now areas like this I think can kind of resemble what you see in a so-called cellular intramuscular myxoma. Intramuscular myxomas are usually very blue and myxoid very hypocellular but sometimes they get more fibrous and more cellular areas. And on a needle biopsy I think that can be challenging. So I think usually with some experience you can tell them apart on H and E most of the time but when I have any doubt I just do a MUC4 stain. The MUC4 is negative and on a needle it looks like a myxoma with some kind of fibrous or a little bit more cellular areas and then I just say that it's probably a cellular intramuscular myxoma. So I think MUC4",
"corrected_text": " Here's again the myxoid background I really think this is very helpful. The very very fine delicate collagen that you see. Now areas like this I think can kind of resemble what you see in a so-called cellular intramuscular myxoma. Intramuscular myxomas are usually very blue and myxoid very hypocellular but sometimes they get more fibrous and more cellular areas. And on a needle biopsy I think that can be challenging. So I think usually with some experience you can tell them apart on H and E most of the time but when I have any doubt I just do a MUC4 stain. The MUC4 is negative and on a needle it looks like a myxoma with some kind of fibrous or a little bit more cellular areas and then I just say that it's probably a cellular intramuscular myxoma. So I think MUC4",
"med_umls_ids": "[[{'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'myxoid', 'concept_id': 'C0205295', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}], [{'entity': 'narrator', 'concept_id': 'C1135957', 'confidence': 0.7711340188980103}, {'entity': 'cellular', 'concept_id': 'C0007634', 'confidence': 0.9999999403953552}, {'entity': 'intramuscular', 'concept_id': 'C0442117', 'confidence': 1.0}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}, {'entity': 'cellular areas', 'concept_id': 'C0007634', 'confidence': 0.7882957458496094}], [{'entity': 'MUC4', 'concept_id': 'C1417496', 'confidence': 0.9999999403953552}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'confirm', 'concept_id': 'C0521093', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'cellular intramuscular myxoma', 'concept_id': 'C1334260', 'confidence': 0.8910117149353027}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_554",
"caption_rating": "8"
},
{
"": "1008983",
"caption": "Involvement around damaged nerves is a common feature of sarcoid granulomatous inflammation.",
"image_path": "udoW6VSqsm4_image_f8689d95-7530-4b83-898a-d4cd00fc356d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['sarcoid granulomatous inflammation', 'involvement around nerves', 'sarcoid granulomatous inflammation', 'involvement around nerves']",
"noisy_text": " That's the tuberculoid. Yeah, good. The tuberculoid form of leprosy gives you sarcoidal granulomatous inflammation. It's elongated. Very good. That's exactly right. What else can give you sarcoidal granulomatous inflammation? Can I ask a quick question about the sarcoid with the two... The nansins? So, I had a case, I saw a case that looked kind of horizontal, but it was sarcoid. And so, what other ways can you tell? Sometimes it can be difficult, but usually you're going to see involvement around nerves damaged nerves. You're about to get sarcoidal granulomatous inflammation. They always have very high risk inflammatory reactions. They just wipe out the nerves. So, that's helpful. Wasn't",
"corrected_text": " That's the tuberculoid. Yeah, good. The tuberculoid form of leprosy gives you sarcoidal granulomatous inflammation. It's elongated. Very good. That's exactly right. What else can give you sarcoidal granulomatous inflammation? Can I ask a quick question about the sarcoid with the two... The sarcoidosis? So, I had a case, I saw a case that looked kind of horizontal, but it was sarcoid. And so, what other ways can you tell? Sometimes it can be difficult, but usually you're going to see involvement around nerves damaged nerves. You're about to get sarcoidal granulomatous inflammation. They always have very high risk inflammatory reactions. They just wipe out the nerves. So, that's helpful. Wasn't",
"med_umls_ids": "[[{'entity': 'Tuberculoid', 'concept_id': 'C0544783', 'confidence': 0.8459237217903137}, {'entity': 'leprosy', 'concept_id': 'C0023343', 'confidence': 1.0}, {'entity': 'sarcoid', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'granulomatous inflammation', 'concept_id': 'C0553697', 'confidence': 1.0}], [{'entity': 'Involvement', 'concept_id': 'C1314939', 'confidence': 1.0}, {'entity': 'damaged nerves', 'concept_id': 'C3887709', 'confidence': 0.8087002038955688}, {'entity': 'sarcoid', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'granulomatous inflammation', 'concept_id': 'C0553697', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_555",
"caption_rating": "8"
},
{
"": "1007111",
"caption": "Re-biopsy showed no more granulomas after treatment for sarcoidosis.",
"image_path": "sDFjOtMAYrk_image_bd78a499-7df9-4eaa-9442-5bfa70ba065e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['granuloma', 'granuloma', 'lamina propria', 'Crohn\u2019s disease', 'infectious process', 'sarcoidosis', 'uveitis']",
"noisy_text": " I like this place. So if you have big coalescing masses of granuloma, expanding your lamina propria, think something other than Crohn's. Think of infectious process, especially if they're necrotizing, but even if they're not, and also think of sarcoid. This patient had sarcoid. So I said, this is probably not IBD, clinicians came down, we want to look at the biopsy, of course. It turns out that they went back and talked to the patient. The patient has a history of uveitis with characteristic features that were good for sarcoidosis. Nobody knew about they treated the patient for sarcoid, re-biopsied the patient. And he was fine. There were no more granulomas on multiple repeat biopsies. And now compare those grannies with the grannies in Crohn's. So here's",
"corrected_text": " I like this place. So if you have big coalescing masses of granuloma, expanding your lamina propria, think something other than Crohn's. Think of infectious process, especially if they're necrotizing, but even if they're not, and also think of sarcoid. This patient had sarcoid. So I said, this is probably not IBD, clinicians came down, we want to look at the biopsy, of course. It turns out that they went back and talked to the patient. The patient has a history of uveitis with characteristic features that were good for sarcoidosis. Nobody knew about they treated the patient for sarcoid, re-biopsied the patient. And he was fine. There were no more granulomas on multiple repeat biopsies. And now compare those grannies with the grannies in Crohn's. So here's",
"med_umls_ids": "[[{'entity': 'Coalescing masses', 'concept_id': 'C4727092', 'confidence': 0.5960795283317566}, {'entity': 'granuloma', 'concept_id': 'C0018188', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'infectious process', 'concept_id': 'C0745283', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'Crohn\u2019s disease', 'concept_id': 'C0010346', 'confidence': 0.8916962146759033}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'history', 'concept_id': 'C0019664', 'confidence': 1.0}, {'entity': 'uveitis', 'concept_id': 'C0042164', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}], [{'entity': 'Re-biopsy', 'concept_id': 'C0005558', 'confidence': 0.6681398749351501}, {'entity': 'granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}, {'entity': 'treatment', 'concept_id': 'C0039798', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_556",
"caption_rating": "8"
},
{
"": "1007597",
"caption": "Presence of a tiny nested component and melanoma in situ component that stained with MART1.",
"image_path": "jCw_NtnS6XU_image_17f9e3d0-66e6-4107-9054-53b31d3f5587.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " on this side we have S100 striking staining throughout the dermis and on this side, those atypical spindle cells are totally negative for MART1. All you see there are a couple little nests. This one had a tiny, tiny component that was nested as well as a melanoma in situ component. That part stained with MART1. The rest of the lesion was totally negative and just stained with S100. So this is a great example to help explain that you're usually not going to have MART1 and HMB45. Those specific markers are not gonna usually be present in pure desmoplastic melanomas. I wanted to show you a comparison. We looked at",
"corrected_text": " on this side we have S100 striking staining throughout the dermis and on this side, those atypical spindle cells are totally negative for MART1. All you see there are a couple little nests. This one had a tiny, tiny component that was nested as well as a melanoma in situ component. That part stained with MART1. The rest of the lesion was totally negative and just stained with S100. So this is a great example to help explain that you're usually not going to have MART1 and HMB45. Those specific markers are not gonna usually be present in pure desmoplastic melanomas. I wanted to show you a comparison. We looked at",
"med_umls_ids": "[[{'entity': 'S100', 'concept_id': 'C3273837', 'confidence': 1.0}, {'entity': 'staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'side', 'concept_id': 'C0441987', 'confidence': 1.0}, {'entity': 'atypical', 'concept_id': 'C0205182', 'confidence': 1.0}, {'entity': 'spindle cells', 'concept_id': 'C0682540', 'confidence': 1.0}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'MART1', 'concept_id': 'C1334510', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'melanoma', 'concept_id': 'C0025202', 'confidence': 1.0}, {'entity': 'in situ component', 'concept_id': 'C1882484', 'confidence': 0.7850481271743774}, {'entity': 'stained', 'concept_id': 'C2986582', 'confidence': 1.0}, {'entity': 'MART1', 'concept_id': 'C1334510', 'confidence': 1.0}], [{'entity': 'MART1', 'concept_id': 'C1334510', 'confidence': 1.0}, {'entity': 'HMB45', 'concept_id': 'C1440756', 'confidence': 1.0}, {'entity': 'desmoplastic', 'concept_id': 'C1511789', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_557",
"caption_rating": "9"
},
{
"": "1009173",
"caption": "The lesion tends to occur along the ulnar aspect of the fifth digit and can be bilateral.",
"image_path": "8S4LeiO6Bbk_image_2c74cb7e-8b94-4978-b90b-ef18b3b1034a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['ulnar aspect of the fifth digit', 'nerve fascicles', 'spindle-shaped cells', 'rudimentary supernumerary digit', 'ulnar aspect of the fifth digit', 'acquired digital fibroma', 'acquired digital fibrokeratoma', 'trichilemmal cyst']",
"noisy_text": " core here we've got several well-defined nerve fascicles and the spindled cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions of course tend to occur along the ulnar eye aspect of the fifth digit. They're not infrequently bilateral and the key differential here of course is an acquired digital fibroma or an acquired digital fibrocarotoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if",
"corrected_text": " core here we've got several well-defined nerve fascicles and the spindle cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions of course tend to occur along the ulnar eye aspect of the fifth digit. They're not infrequently bilateral and the key differential here of course is an acquired digital fibroma or an acquired digital fibrokeratoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if",
"med_umls_ids": "[[{'entity': 'Well-defined nerve fascicles', 'concept_id': 'C1185741', 'confidence': 0.5682494640350342}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'S100', 'concept_id': 'C3273837', 'confidence': 1.0}, {'entity': 'SOX10', 'concept_id': 'C1420317', 'confidence': 0.9999998807907104}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'rudimentary supernumerary digit', 'concept_id': 'C0152427', 'confidence': 0.8142021894454956}], [{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'ulnar', 'concept_id': 'C0442044', 'confidence': 1.0}, {'entity': 'aspect', 'concept_id': 'C1547011', 'confidence': 1.0}, {'entity': 'fifth digit', 'concept_id': 'C0230403', 'confidence': 0.912693440914154}, {'entity': 'bilateral', 'concept_id': 'C0238767', 'confidence': 1.0}], [{'entity': 'differential diagnosis', 'concept_id': 'C0011906', 'confidence': 1.0}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}, {'entity': 'digital fibroma', 'concept_id': 'C4538745', 'confidence': 0.8997364640235901}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}], [{'entity': 'Trichilemmal cyst', 'concept_id': 'C2266788', 'confidence': 1.0}, {'entity': 'biopsy specimen', 'concept_id': 'C0677862', 'confidence': 1.0}, {'entity': 'slide number', 'concept_id': 'C3828004', 'confidence': 0.8261933326721191}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_558",
"caption_rating": "8"
},
{
"": "1006186",
"caption": "Enlarged nuclei that are about six times the size of normal prostate nuclei.",
"image_path": "iklRyY1nBIE_image_f98d30b9-5304-4210-b9f8-92fc429a8533.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['basal cells at the periphery', 'enlarged nuclei', 'intraductal carcinoma of the prostate', 'adjacent invasive tumor', 'previously benign gland', 'basal cells at the periphery', 'enlarged nuclei', 'intraductal carcinoma of the prostate', 'adjacent invasive tumor', 'previously benign gland']",
"noisy_text": " Let me show you what the cocktail looks like. Again, this is the pin three, or some call it pin four. You have the P63, you have the hemoglobin cytokeratin, and then you have the racemase, which is the pink chromogen. And as you can see, as I demonstrated on the H&E, basal cells are indeed present. This is too much for high-grade pin. This is basically what is called a solid cribriform kind of pattern, in which over 50% of the lumen is filled by tumor cells. So this is way too much for high-grade pin. But it's not invasive, because you have basal cells at the periphery. And the nuclei are enlarged. These nuclei are about six times the size of normal prostate nuclei. So this case meets the criteria for introductal carcinoma of the prostate. There is an invasive component, which you can see is negative for basal cell markers. But you have the introductal component. And this is a very interesting entity. The vast majority of cases, and I'll show you the corresponding radical prostatectomy specimens in a second, but the vast majority of these so-called introductal carcinoma of the prostate is due to invasion, colonization by adjacent invasive tumor. And it usually occurs in patients that have high-volume tumors. When I show you the corresponding radical prostatectomies, you'll see what I'm talking about. You usually don't have this in patients in their radicals that have 5% prostate cancer or 10% prostate cancer. It's usually patients that have extensive prostate cancer involvement, and the invasive glands basically have nowhere else to go but to colonize adjacent benign glands. And I'll demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues,",
"corrected_text": " Let me show you what the cocktail looks like. Again, this is the pin three, or some call it pin four. You have the P63, you have the hemoglobin cytokeratin, and then you have the racemase, which is the AMACR. And as you can see, as I demonstrated on the H&E, basal cells are indeed present. This is too much for high-grade pin. This is basically what is called a solid cribriform kind of pattern, in which over 50% of the lumen is filled by tumor cells. So this is way too much for high-grade pin. But it's not invasive, because you have basal cells at the periphery. And the nuclei are enlarged. These nuclei are about six times the size of normal prostate nuclei. So this case meets the criteria for intraductal carcinoma of the prostate. There is an invasive component, which you can see is negative for basal cell markers. But you have the intraductal component. And this is a very interesting entity. The vast majority of cases, and I'll show you the corresponding radical prostatectomy specimens in a second, but the vast majority of these so-called intraductal carcinoma of the prostate is due to invasion, colonization by adjacent invasive tumor. And it usually occurs in patients that have high-volume tumors. When I show you the corresponding radical prostatectomies, you'll see what I'm talking about. You usually don't have this in patients in their radicals that have 5% prostate cancer or 10% prostate cancer. It's usually patients that have extensive prostate cancer involvement, and the invasive glands basically have nowhere else to go but to colonize adjacent benign glands. And I'demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues,",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'cocktail', 'concept_id': 'C0678420', 'confidence': 1.0}, {'entity': 'markers', 'concept_id': 'C0181734', 'confidence': 0.890313982963562}, {'entity': 'intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate diagnosis', 'concept_id': 'C0011900', 'confidence': 0.7927443981170654}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'basal cells', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}], [{'entity': 'Enlarged nuclei', 'concept_id': 'C4013177', 'confidence': 0.7774685621261597}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'normal', 'concept_id': 'C0205307', 'confidence': 1.0}], [{'entity': 'Intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'invasion', 'concept_id': 'C1269955', 'confidence': 1.0}, {'entity': 'colonization', 'concept_id': 'C4289767', 'confidence': 1.0}, {'entity': 'adjacent', 'concept_id': 'C0205117', 'confidence': 1.0}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}], [{'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'benign gland', 'concept_id': 'C0205183', 'confidence': 0.7986565828323364}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_559",
"caption_rating": "8"
},
{
"": "1006587",
"caption": "Ectatic vessels are present in the papillary dermis with pallor consistent with edema and perivascular infiltrate of lymphocytes.",
"image_path": "hoV-JkD6Wb0_image_22f9d1d9-6fad-4df6-a025-36c37c0d46db.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['ectatic vessels', 'papillary dermis', 'perivascular infiltrate of lymphocytes', 'collections of immune cells', 'narrow cuff of mononuclear cells', 'ectatic vessels', 'papillary dermis', 'perivascular infiltrate of lymphocytes', 'collections of immune cells', 'narrow cuff of mononuclear cells']",
"noisy_text": " and we'll take a look at two of them, you had to review similar findings, bisected punch. And as expected, there are ectatic vessels here. Let me tilt the slide here. And the papillary dermis, a little bit of pallor consistent with edema, a little bit of a perivascular infiltrate of lymphocytes. And then present throughout the dermis, there are a few collections of epithelioid histiocytes. Here, there's one right there. And down here, we have another collection of epithelioid histiocytes. These are surrounded by a narrow cuff of mononuclear cells, but many",
"corrected_text": " and we'll take a look at two of them, you had to review similar findings, bisected punch. And as expected, there are ectatic vessels here. Let me tilt the slide here. And the papillary dermis, a little bit of pallor consistent with edema, a little bit of a perivascular infiltrate of lymphocytes. And then present throughout the dermis, there are a few collections of epithelioid histiocytes. Here, there's one right there. And down here, we have another collection of epithelioid histiocytes. These are surrounded by a narrow cuff of mononuclear cells, but many",
"med_umls_ids": "[[{'entity': 'Ectatic vessels', 'concept_id': 'C0005847', 'confidence': 0.7720959186553955}, {'entity': 'papillary dermis', 'concept_id': 'C0682598', 'confidence': 1.0}, {'entity': 'pallor', 'concept_id': 'C0030232', 'confidence': 1.0}, {'entity': 'consistent with', 'concept_id': 'C0332290', 'confidence': 1.0}, {'entity': 'edema', 'concept_id': 'C0013604', 'confidence': 0.9999999403953552}, {'entity': 'perivascular', 'concept_id': 'C0442165', 'confidence': 1.0}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}], [{'entity': 'Collections', 'concept_id': 'C0600644', 'confidence': 0.8663196563720703}, {'entity': 'immune cells', 'concept_id': 'C4330475', 'confidence': 0.8268961906433105}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'surrounded', 'concept_id': 'C1282914', 'confidence': 1.0}, {'entity': 'cuff', 'concept_id': 'C0441107', 'confidence': 1.0}, {'entity': 'mononuclear cells', 'concept_id': 'C0806987', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_560",
"caption_rating": "9"
},
{
"": "1008449",
"caption": "Low-grade fibromyxoid sarcoma should be excluded based on these features.",
"image_path": "QDb68_G1HR4_image_9806226e-d95c-48e6-9687-d06571da83a6.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " Fibrous pink stuff mingled with pale blue myxoid stuff and more cellular areas like this intermingled with less cellular areas. Those features right there always make me think I have to exclude low grade fibromyxoid sarcoma with some practice and hopefully after this video, you'll have seen enough cases that you can start to recognize there are some very distinct features I think that at higher power that are kind of subtle, the nuances like that fine collagen and something like the vascular pattern that can help you sort this out and then of course we can use ancillary testing but I think from low power, it's important to always have this entity in your mind when you see a soft tissue tumor that looks benign and has kind of pinkish and bluish",
"corrected_text": " Fibrous pink stuff mingled with pale blue myxoid stuff and more cellular areas like this intermingled with less cellular areas. Those features right there always make me think I have to exclude low grade fibromyxoid sarcoma with some practice and hopefully after this video, you'll have seen enough cases that you can start to recognize there are some very distinct features I think that at higher power that are kind of subtle, the nuances like that fine collagen and something like the vascular pattern that can help you sort this out and then of course we can use ancillary testing but I think from low power, it's important to always have this entity in your mind when you see a soft tissue tumor that looks benign and has kind of pinkish and bluish",
"med_umls_ids": "[[{'entity': 'Fibrous pink', 'concept_id': 'C0439709', 'confidence': 0.7378140091896057}, {'entity': 'cellular areas', 'concept_id': 'C0007634', 'confidence': 0.7882957458496094}], [{'entity': 'Low-grade fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.9999998807907104}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}], [{'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'power', 'concept_id': 'C0032863', 'confidence': 1.0}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'vascular pattern', 'concept_id': 'C1446316', 'confidence': 0.8019405007362366}, {'entity': 'differentiate', 'concept_id': 'C0205615', 'confidence': 0.9999998807907104}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}], [{'entity': 'Ancillary testing', 'concept_id': 'C1319071', 'confidence': 0.8779969215393066}, {'entity': 'confirm', 'concept_id': 'C0521093', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_561",
"caption_rating": "8"
},
{
"": "1005165",
"caption": "MAC is a neoplasm that is diffuse in nature and does not show a lot of mitoses or individual cellular atypia.",
"image_path": "LlPaENuqzVQ_image_e04d68b3-554b-418e-b777-8f951e77631e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['MAC looks like a syringoma.']",
"noisy_text": " And basically, another name for MAC that I actually like better is syringomatous carcinoma because it looks like a syringoma. And if you look at the individual cells, usually you don't see a lot of mitoses. There's not a lot of individual cellular atypia, not a lot of pleomorphism. It's really a neoplasm that causes problems because of its diffuse nature. Some cancers are aggressive because they metastasize. Some are more aggressive because they just like crab. They just gradually erode everything and they just destroy everything in their path. And so this is more that sort of thing and it goes deep. And one other thing that you look for when you're",
"corrected_text": " And basically, another name for MAC that I actually like better is syringomatous carcinoma because it looks like a syringoma. And if you look at the individual cells, usually you don't see a lot of mitoses. There's not a lot of individual cellular atypia, not a lot of pleomorphism. It's really a neoplasm that causes problems because of its diffuse nature. Some cancers are aggressive because they metastasize. Some are more aggressive because they just like crab. They just gradually erode everything and they just destroy everything in their path. And so this is more that sort of thing and it goes deep. And one other thing that you look for when you're",
"med_umls_ids": "[[{'entity': 'MAC', 'concept_id': 'C0009545', 'confidence': 0.9999999403953552}, {'entity': 'Mycobacterium avium complex', 'concept_id': 'C0026914', 'confidence': 1.0}, {'entity': 'syringomatous carcinoma', 'concept_id': 'C0346027', 'confidence': 1.0}, {'entity': 'syringoma', 'concept_id': 'C0206673', 'confidence': 1.0}], [{'entity': 'MAC', 'concept_id': 'C0009545', 'confidence': 0.9999999403953552}, {'entity': 'neoplasm', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'diffuse', 'concept_id': 'C0205219', 'confidence': 1.0}, {'entity': 'nature', 'concept_id': 'C0349590', 'confidence': 1.0}, {'entity': 'mitoses', 'concept_id': 'C0026255', 'confidence': 1.0}, {'entity': 'cellular atypia', 'concept_id': 'C0333865', 'confidence': 0.9999999403953552}], [{'entity': 'MAC', 'concept_id': 'C0009545', 'confidence': 0.9999999403953552}, {'entity': 'deep cancer', 'concept_id': 'C0006826', 'confidence': 0.6357579231262207}, {'entity': 'destroys', 'concept_id': 'C0681205', 'confidence': 0.6218703985214233}, {'entity': 'path', 'concept_id': 'C1705483', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_562",
"caption_rating": "7"
},
{
"": "1008757",
"caption": "CD20 IHC is strongly positive, indicating non-Hodgkin lymphoma, possibly diffuse large B cell type.",
"image_path": "r7OA0Trj5hQ_image_4b10e799-b399-4e91-af37-ab7b4f335854.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['poorly differentiated cells', 'lamina propria', 'lymphoma', 'CD20 IHC positive', 'poorly differentiated cells', 'lamina propria', 'lymphoma', 'CD20 IHC positive']",
"noisy_text": " Here, what is happening? Very poorly differentiated cells, high grade malignancy. Again, definitely, it is proliferative disease with the ATP. Again, invasion metastasis, we cannot see from this picture. But whenever you see this much of poorly differentiated cells in the gastric biopsy or in the colonic biopsy, and predominantly the atypical cells are situated in the lamina propria, think of lymphoma. This is a CD20 IHC, strongly positive. So this is a non-Hodgkin's lymphoma, possibly diffuse large B cell type. So we are done with surface epithelium. We are done",
"corrected_text": " Here, what is happening? Very poorly differentiated cells, high grade malignancy. Again, definitely, it is proliferative disease with the ATP. Again, invasion metastasis, we cannot see from this picture. But whenever you see this much of poorly differentiated cells in the gastric biopsy or in the colonic biopsy, and predominantly the atypical cells are situated in the lamina propria, think of lymphoma. This is a CD20 IHC, strongly positive. So this is a non-Hodgkin's lymphoma, possibly diffuse large B cell type. So we are done with surface epithelium. We are done",
"med_umls_ids": "[[{'entity': 'Poorly differentiated cells', 'concept_id': 'C0205617', 'confidence': 0.9036805629730225}, {'entity': 'lymphoma', 'concept_id': 'C0024299', 'confidence': 1.0}], [{'entity': 'CD20', 'concept_id': 'C1417326', 'confidence': 1.0}, {'entity': 'IHC', 'concept_id': 'C0021044', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'non-Hodgkin lymphoma', 'concept_id': 'C0024305', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_563",
"caption_rating": "9"
},
{
"": "1005073",
"caption": "Histopathological description of melanoma in situ involving the nail unit.",
"image_path": "8S4LeiO6Bbk_image_4f0e36fc-59d1-44c7-8221-524493485e08.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Melanoma in situ involving the nail unit.']",
"noisy_text": " sometimes a little bit cleaner than the MART1 stain, which is a cytoplasmic stain. So first case, slides one and two represented melanoma in situ involving the nail unit. Very nice example. I'm sure many of you don't see many nail biopsies, so just really nicely taken. The problem with these biopsies of course is that they're difficult and oftentimes the tissue is fragmented or squeezed or if the nail plate happens to be removed, a lot of the matrix will adhere to the nail plate. So again, a very, very nice biopsy. Moving on to slide number three, we're changing directions here. Here we have several fragments of tissue and in looking at this, this is pretty clear that we're dealing",
"corrected_text": " sometimes a little bit cleaner than the MART1 stain, which is a cytoplasmic stain. So first case, slides one and two represented melanoma in situ involving the nail unit. Very nice example. I'm sure many of you don't see many nail biopsies, so just really nicely taken. The problem with these biopsies of course is that they're difficult and oftentimes the tissue is fragmented or squeezed or if the nail plate happens to be removed, a lot of the matrix will adhere to the nail plate. So again, a very, very nice biopsy. Moving on to slide number three, we're changing directions here. Here we have several fragments of tissue and in looking at this, this is pretty clear that we're dealing",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'melanoma', 'concept_id': 'C0025202', 'confidence': 1.0}, {'entity': 'in situ', 'concept_id': 'C0444498', 'confidence': 0.9999999403953552}, {'entity': 'nail unit', 'concept_id': 'C4758673', 'confidence': 0.8730567693710327}], [{'entity': 'Difficulty', 'concept_id': 'C1299586', 'confidence': 1.0}, {'entity': 'nail', 'concept_id': 'C0027342', 'confidence': 1.0}, {'entity': 'biopsies', 'concept_id': 'C0005558', 'confidence': 1.0}, {'entity': 'tissue fragmentation', 'concept_id': 'C0332472', 'confidence': 0.8164394497871399}, {'entity': 'squeezing', 'concept_id': 'C1997001', 'confidence': 0.9174635410308838}], [{'entity': 'fragments', 'concept_id': 'C0332255', 'confidence': 1.0}, {'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'observed', 'concept_id': 'C1441672', 'confidence': 1.0}, {'entity': 'slide number', 'concept_id': 'C3828004', 'confidence': 0.8261933326721191}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_564",
"caption_rating": "8"
},
{
"": "1004557",
"caption": "Smooth muscle bundles are infiltrated by lymphomatous cells in the wall of the small bowel, causing abnormal appearance and ulceration of the mucosa.",
"image_path": "gcLu6sNtYoc_image_fcb0d9d7-5bc4-4b78-8660-87d8e30e190d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Hematopathology', 'Gastrointestinal', 'Pulmonary']",
"roi_text": "['smooth muscle bundles', 'lymphomatous cells', 'wall of the small bowel', 'ulceration of the mucosa', 'fibrinoid inflammatory ulcer exudate', 'GI bleeding', 'smooth muscle bundles', 'lymphomatous cells', 'wall of the small bowel', 'ulceration of the mucosa', 'fibrinoid inflammatory ulcer exudate', 'GI bleeding']",
"noisy_text": " see some smooth muscle bundles here, but this is very much infiltrated by lymphomatous cells, and then of course, we have the serosa. So we can see that there is a very abnormal infiltrate of this bluish appearing cells throughout the wall of the small bowel. In some areas, it is full thickness. In other areas, it just involves part of the wall, and in fact, in this area, we can see that this has caused ulceration of the mucosa. There is this fibrinoid inflammatory ulcer exudate here, and of course, this means that it can give rise to GI bleeding. Taking a",
"corrected_text": " see some smooth muscle bundles here, but this is very much infiltrated by lymphomatous cells, and then of course, we have the serosa. So we can see that there is a very abnormal infiltrate of this bluish appearing cells throughout the wall of the small bowel. In some areas, it is full thickness. In other areas, it just involves part of the wall, and in fact, in this area, we can see that this has caused ulceration of the mucosa. There is this fibrinoid inflammatory ulcer exudate here, and of course, this means that it can give rise to GI bleeding. Taking a",
"med_umls_ids": "[[{'entity': 'Smooth muscle', 'concept_id': 'C1267092', 'confidence': 1.0}, {'entity': 'bundles', 'concept_id': 'C3658308', 'confidence': 0.8706014752388}, {'entity': 'infiltrated', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'lymphomatous cells', 'concept_id': 'C0883208', 'confidence': 0.8273725509643555}, {'entity': 'wall', 'concept_id': 'C0677535', 'confidence': 1.0}, {'entity': 'small bowel', 'concept_id': 'C0021852', 'confidence': 1.0}, {'entity': 'abnormal', 'concept_id': 'C0205161', 'confidence': 1.0}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'ulceration', 'concept_id': 'C0041582', 'confidence': 1.0}, {'entity': 'mucosa', 'concept_id': 'C0026724', 'confidence': 1.0}], [{'entity': 'abnormal', 'concept_id': 'C0205161', 'confidence': 1.0}, {'entity': 'GI bleeding', 'concept_id': 'C0017181', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "644.0",
"width": "1280.0",
"id": "test_565",
"caption_rating": "9"
},
{
"": "1004798",
"caption": "Presence of plasma cells within the infiltrate can help distinguish between the condition and Kaposi's sarcoma. Negative HHV8 stain also rules out Kaposi's sarcoma. Diagnosis in this case is targetoid hemosiderotic hemangioma, which commonly appears on the trunk or extremities and is characterized by a central dark blue or purple papule surrounded by a zone of power and then an eccentric ring. Lesions stain frequently with CD34 and are strongly positive for D240, indicating lymphatic origin. The tumor is biphasic with dilated vascular channels and papillary projections.",
"image_path": "8S4LeiO6Bbk_image_b4da8638-1f38-4754-bdde-a6e5bc353f02.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['plasma cells within the infiltrate', 'central dark blue or purple papule', 'eccentric ring', 'papillary projections', 'plump endothelial', 'plasma cells within the infiltrate', 'central dark blue or purple papule', 'eccentric ring', 'papillary projections', 'plump endothelial']",
"noisy_text": " plasma cells within the infiltrate. And plasma cells within the infiltrate can be very useful in discriminating between this condition and Kaposi's sarcoma. In this particular case, also the HHV8 stain was a negative, which would be positive in Kaposi's sarcoma. So the diagnosis in this case was a targetoid hemocidiotic hemangioma, sometimes known as a hobnail hemangioma. Frequently has a characteristic clinical appearance, occurs commonly on the trunk or extremities. It is characterized usually by a central dark blue or purple papule surrounded by a zone of power and then an ecomotic ring, which will slowly risk halt. These lesions will stain, frequently with CD34, but also are strongly positive for D240. So they probably are of lymphatic origin rather than vascular origin. What one looks for is a biphasic vascular tumor with this central area characterized by these dilated vascular channels. Let's look at the bottom piece, which frequently do contain these papillary projections, which protrude into the lumina, these plump endothelial cells, and",
"corrected_text": " plasma cells within the infiltrate. And plasma cells within the infiltrate can be very useful in discriminating between this condition and Kaposi's sarcoma. In this particular case, also the HHV8 stain was a negative, which would be positive in Kaposi's sarcoma. So the diagnosis in this case was a targetoid hemosiderotic hemangioma, sometimes known as a hobnail hemangioma. Frequently has a characteristic clinical appearance, occurs commonly on the trunk or extremities. It is characterized usually by a central dark blue or purple papule surrounded by a zone of power and then an eccentric ring, which will slowly risk halt. These lesions will stain, frequently with CD34, but also are strongly positive for D240. So they probably are of lymphatic origin rather than vascular origin. What one looks for is a biphasic vascular tumor with this central area characterized by these dilated vascular channels. Let's look at the bottom piece, which frequently do contain these papillary projections, which protrude into the lumina, these plump endothelial cells, and",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': \"Kaposi's sarcoma\", 'concept_id': 'C0036220', 'confidence': 1.0}, {'entity': 'Negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'rules', 'concept_id': 'C0870077', 'confidence': 1.0}, {'entity': \"Kaposi's sarcoma\", 'concept_id': 'C0036220', 'confidence': 1.0}, {'entity': 'Diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'targetoid hemosiderotic hemangioma', 'concept_id': 'C0346076', 'confidence': 0.9999999403953552}, {'entity': 'trunk', 'concept_id': 'C0225442', 'confidence': 0.9999999403953552}, {'entity': 'extremities', 'concept_id': 'C0015385', 'confidence': 1.0}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'central dark blue', 'concept_id': 'C1958010', 'confidence': 0.6706290245056152}, {'entity': 'purple papule', 'concept_id': 'C0439542', 'confidence': 0.759922981262207}, {'entity': 'surrounded', 'concept_id': 'C1282914', 'confidence': 1.0}, {'entity': 'zone', 'concept_id': 'C1710706', 'confidence': 1.0}, {'entity': 'power', 'concept_id': 'C0032863', 'confidence': 1.0}, {'entity': 'eccentric ring', 'concept_id': 'C0439740', 'confidence': 0.9041137099266052}, {'entity': 'Lesions', 'concept_id': 'C0221198', 'confidence': 1.0}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'CD34', 'concept_id': 'C0054953', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'D240', 'concept_id': 'C3766973', 'confidence': 0.5323090553283691}, {'entity': 'lymphatic origin', 'concept_id': 'C0229889', 'confidence': 0.7706887125968933}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'biphasic', 'concept_id': 'C0205184', 'confidence': 1.0}, {'entity': 'dilated', 'concept_id': 'C0700124', 'confidence': 0.9999999403953552}, {'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}, {'entity': 'papillary projections', 'concept_id': 'C0016538', 'confidence': 0.7451471090316772}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_566",
"caption_rating": "9"
},
{
"": "1008486",
"caption": "Lymphocytes are hyperchromatic and can be used as a reference for comparison.",
"image_path": "Wiyo6taYRF4_image_7003a78c-a71f-4f57-a2e5-f20e15371095.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Hematopathology', 'Neuropathology', 'Cytopathology']",
"roi_text": "['Vesicular nuclei', 'Lymphocytes', 'Vesicular nuclei', 'Lymphocytes']",
"noisy_text": " very actively proliferating. So let's see one example of vesicular nuclei here. So these are the nuclei. So if you see here, the nucleus has got a very finely lightly strained chromatin and a prominent big eosinophilic nuclei. So normally, whenever we see a vesicular nuclei, they're generally accompanied by a prominent big eosinophilic nuclei. So whenever we are describing a vesicular nuclei, that is, we are saying that the nucleus is lightly strained, we are also saying that the cell is also having a prominent nuclei. And if you compare these cells with few of the lymphocytes here, so lymphocytes are the best cell in reference. And you can always compare the nucleus which you are typing with the lymphocytes in vicinity. And lymphocytes are usually hyperchromatic, that is, they're darkly strained. So as compared to this cell, you see that the nucleus is",
"corrected_text": " very actively proliferating. So let's see one example of vesicular nuclei here. So these are the nuclei. So if you see here, the nucleus has got a very finely lightly strained chromatin and a prominent big eosinophilic nuclei. So normally, whenever we see a vesicular nuclei, they're generally accompanied by a prominent big eosinophilic nuclei. So whenever we are describing a vesicular nuclei, that is, we are saying that the nucleus is lightly strained, we are also saying that the cell is also having a prominent nuclei. And if you compare these cells with few of the lymphocytes here, so lymphocytes are the best cell in reference. And you can always compare the nucleus which you are typing with the lymphocytes in vicinity. And lymphocytes are usually hyperchromatic, that is, they're darkly strained. So as compared to this cell, you see that the nucleus is",
"med_umls_ids": "[[{'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'proliferating', 'concept_id': 'C1514485', 'confidence': 1.0}], [{'entity': 'Vesicular nuclei', 'concept_id': 'C2325471', 'confidence': 0.7651268839836121}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'chromatin', 'concept_id': 'C0008546', 'confidence': 1.0}, {'entity': 'eosinophilic nucleus', 'concept_id': 'C0333930', 'confidence': 0.7939648628234863}], [{'entity': 'Lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'hyperchromatic', 'concept_id': 'C0333911', 'confidence': 1.0}, {'entity': 'comparison', 'concept_id': 'C1707455', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1152.0",
"id": "test_567",
"caption_rating": "8"
},
{
"": "1007348",
"caption": "Poorly differentiated cells and high grade malignancy are present in the biopsy.",
"image_path": "r7OA0Trj5hQ_image_a44d68c9-acf0-4267-9a47-d8084aad27ce.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['signet ring cells', 'poorly differentiated cells', 'gastric biopsy', 'colonic biopsy']",
"noisy_text": " And this, I got it again from Twitter, I think from Sanjay Bhavatiya, pathologists who missed signet cells, pathologists who are missing the signet cells, pathologists who will be missing the signet cell carcinoma. So it's a very, very, very difficult condition. We have to keep our eyes wide. Leave open to see these signet cells, especially in biopsies. Here, what is happening? Very poorly differentiated cells, high grade malignancy. Again, definitely, it is proliferative disease with the ATP. Again, invasion metastasis, we cannot see from this picture. But whenever you see this much of poorly differentiated cells in the gastric biopsy or in the colonic biopsy, and predominantly the atypical",
"corrected_text": " And this, I got it again from Twitter, I think from Sanjay Bhavatiya, pathologists who missed signet cells, pathologists who are missing the signet cells, pathologists who will be missing the signet cell carcinoma. So it's a very, very, very difficult condition. We have to keep our eyes wide. Leave open to see these signet cells, especially in biopsies. Here, what is happening? Very poorly differentiated cells, high grade malignancy. Again, definitely, it is proliferative disease with the ATP. Again, invasion metastasis, we cannot see from this picture. But whenever you see this much of poorly differentiated cells in the gastric biopsy or in the colonic biopsy, and predominantly the atypical",
"med_umls_ids": "[[{'entity': 'Signet cell carcinoma', 'concept_id': 'C0206696', 'confidence': 0.9410539865493774}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'pathologists', 'concept_id': 'C0334866', 'confidence': 1.0}, {'entity': 'signet ring cells', 'concept_id': 'C0333727', 'confidence': 1.0}], [{'entity': 'Poorly differentiated cells', 'concept_id': 'C0205617', 'confidence': 0.9036805629730225}, {'entity': 'high', 'concept_id': 'C0205250', 'confidence': 1.0}, {'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}], [{'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'proliferative disease', 'concept_id': 'C1332629', 'confidence': 0.8737467527389526}, {'entity': 'ATP', 'concept_id': 'C0001480', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_568",
"caption_rating": "9"
},
{
"": "1006838",
"caption": "There is no pleomorphism seen in this tumor, except for a rare exception in children with pleomorphic myxoid liposarcoma.",
"image_path": "pBR26SS0FX8_image_26cb36c5-d236-4e52-92bb-b58c4b7839ad.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Hematopathology', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " You do not see pleomorphism in this tumor with the rare, rare exception that has been described in children of pleomorphic myxoid liposarcoma, which even though it's in the books, A, I've never seen one and B, the concept does not sit well with me because my understanding is they behave different than regular myxoid liposarcoma, they're more aggressive. A lot of them do not have DDIT3 gene rearrangement. So I kind of think they're a different tumor than this, but I don't know, I don't write the books. So maybe I",
"corrected_text": " You do not see pleomorphism in this tumor with the rare, rare exception that has been described in children of pleomorphic myxoid liposarcoma, which even though it's in the books, A, I've never seen one and B, the concept does not sit well with me because my understanding is they behave different than regular myxoid liposarcoma, they're more aggressive. A lot of them do not have DDIT3 gene rearrangement. So I kind of think they're a different tumor than this, but I don't know, I don't write the books. So maybe I",
"med_umls_ids": "[[{'entity': 'pleomorphism', 'concept_id': 'C0032219', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'rare', 'concept_id': 'C0521114', 'confidence': 1.0}, {'entity': 'exception', 'concept_id': 'C1554961', 'confidence': 1.0}, {'entity': 'children', 'concept_id': 'C0008059', 'confidence': 0.9999998807907104}, {'entity': 'pleomorphic myxoid liposarcoma', 'concept_id': 'C0205825', 'confidence': 0.831965446472168}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_569",
"caption_rating": "7"
},
{
"": "1004744",
"caption": "Histopathological description of an epithelial tumor with interconnected cords and strands.",
"image_path": "8S4LeiO6Bbk_image_d28d47c0-0566-471c-9383-713c820a78ef.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['epithelial tumor', 'cytoplasm', 'vesicular chromatin pattern', 'lymphocytes', 'duct formation']",
"noisy_text": " If we move to higher power, we can see that we're dealing with an epithelial rather than a mosaicable tumor. We've got interconnected cords and strands. We have somewhat of a ribiform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of the cells are round to oval. They're fairly large. These cells have some faint eosinophilic to pale gray cytoplasm, although this cytoplasm is kind of difficult to see. Some of these cells have an evenly dispersed or vesicular chromatin pattern, and other nuclei are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and",
"corrected_text": " If we move to higher power, we can see that we're dealing with an epithelial rather than a mesenchymal tumor. We've got interconnected cords and strands. We have somewhat of a cribriform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of the cells are round to oval. They're fairly large. These cells have some faint eosinophilic to pale gray cytoplasm, although this cytoplasm is kind of difficult to see. Some of these cells have an evenly dispersed or vesicular chromatin pattern, and other nuclei are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'epithelial tumor', 'concept_id': 'C1368683', 'confidence': 0.9999999403953552}, {'entity': 'cords', 'concept_id': 'C0034869', 'confidence': 0.801885187625885}, {'entity': 'strands', 'concept_id': 'C0600383', 'confidence': 0.800572395324707}], [{'entity': 'Cribriform pattern', 'concept_id': 'C1333163', 'confidence': 1.0}, {'entity': 'loose', 'concept_id': 'C0205407', 'confidence': 1.0}, {'entity': 'edematous', 'concept_id': 'C0013604', 'confidence': 1.0}, {'entity': 'vascular stroma', 'concept_id': 'C0005847', 'confidence': 0.8046398758888245}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'cell types', 'concept_id': 'C0007634', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'eosinophilic', 'concept_id': 'C0333930', 'confidence': 1.0}, {'entity': 'pale', 'concept_id': 'C0030232', 'confidence': 1.0}, {'entity': 'gray cytoplasm', 'concept_id': 'C0010834', 'confidence': 0.8177905678749084}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'duct', 'concept_id': 'C0687028', 'confidence': 1.0}, {'entity': 'formation', 'concept_id': 'C0220781', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_570",
"caption_rating": "9"
},
{
"": "1007801",
"caption": "Muscularization of the lamina propria is a criterion for mucosal prolapse in colon, particularly in solitary rectal ulcer syndrome.",
"image_path": "r7OA0Trj5hQ_image_f7e5d5f2-fbd2-484f-bc63-a2fff2d91620.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['muscularization of the lamina propria', 'gastric mucosa', 'chemical gastritis', 'antral biopsy', 'inflammation', 'muscularization of the lamina propria', 'gastric mucosa', 'chemical gastritis', 'antral biopsy', 'inflammation', 'muscularization of the lamina propria', 'gastric mucosa', 'chemical gastritis', 'antral biopsy', 'inflammation']",
"noisy_text": " and in cases of mucosal prolapse in colon. Remember that solitary rectal ulcer syndrome, which is totally misnomer. It is neither solitary, can be seen in other parts other than rectum. There may not be any ulcer, there is no syndrome. So the whole solitary rectal ulcer syndrome is a misnomer. But muscularization of the lamina propria is one of the criteria for mucosal prolapse that is happening in solitary rectal ulcer syndrome. And this is a gastric mucosa. Here when you see muscularization of the lamina propria, you have to think of chemical gastritis. Will it form surface changes? Lamina propria edema and muscularis mucosa coming into the lamina propria. These are the three criterias. When you see it in the anterobiopsy, think of chemical gastritis that can be seen in biliary reflux or NSAID use. Lot of inflammation results. Remember I",
"corrected_text": " and in cases of mucosal prolapse in colon. Remember that solitary rectal ulcer syndrome, which is totally misnomer. It is neither solitary, can be seen in other parts other than rectum. There may not be any ulcer, there is no syndrome. So the whole solitary rectal ulcer syndrome is a misnomer. But muscularization of the lamina propria is one of the criteria for mucosal prolapse that is happening in solitary rectal ulcer syndrome. And this is a gastric mucosa. Here when you see muscularization of the lamina propria, you have to think of chemical gastritis. Will it form surface changes? Lamina propria edema and muscularis mucosa coming into the lamina propria. These are the three criteria. When you see it in the endoscopic biopsy, think of chemical gastritis that can be seen in biliary reflux or NSAID use. Lot of inflammation results. Remember I",
"med_umls_ids": "[[{'entity': 'Muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'criterion', 'concept_id': 'C0243161', 'confidence': 1.0}, {'entity': 'mucosal prolapse', 'concept_id': 'C0034888', 'confidence': 0.826268196105957}, {'entity': 'colon', 'concept_id': 'C0009368', 'confidence': 1.0}, {'entity': 'solitary rectal ulcer syndrome', 'concept_id': 'C4274343', 'confidence': 0.9999999403953552}], [{'entity': 'Muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'gastric mucosa', 'concept_id': 'C0017136', 'confidence': 1.0}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}, {'entity': 'biliary reflux', 'concept_id': 'C0232483', 'confidence': 0.7931289672851562}, {'entity': 'NSAID', 'concept_id': 'C0003211', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_571",
"caption_rating": "8"
},
{
"": "1005994",
"caption": "Increase in eosinophils seen in normal marrow, but in this case, it may be related to the patient\u2019s history of asthma.",
"image_path": "jF_pj4-tEC8_image_e2584fb4-94f6-433a-989a-48f60a75a639.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Pulmonary', 'Cardiac', 'Gastrointestinal']",
"roi_text": "['Increase in eosinophils']",
"noisy_text": " even with the normal marrow, you have some increase in eosinophils, but we know in perspective with this person having asthma, some of that eosinophilia is coming from this person's history of asthma, but there's quite a bit of eosinophils there, but the ME ratio was adequate, maybe four to one in evidence of trilinear hematopoiesis, and so this was a relatively 80% bone marrow with normal cellularity and trilinear hematopoiesis, so very normal looking bone marrow, and I do that, I have a few plasma cells in here as well, but they're not to",
"corrected_text": " even with the normal marrow, you have some increase in eosinophils, but we know in perspective with this person having asthma, some of that eosinophilia is coming from this person's history of asthma, but there's quite a bit of eosinophils there, but the ME ratio was adequate, maybe four to one in evidence of trilinear hematopoiesis, and so this was a relatively 80% bone marrow with normal cellularity and trilinear hematopoiesis, so very normal looking bone marrow, and I do that, I have a few plasma cells in here as well, but they're not to",
"med_umls_ids": "[[{'entity': 'Increase', 'concept_id': 'C0442805', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'normal marrow', 'concept_id': 'C1292131', 'confidence': 0.8076969981193542}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'patient\u2019s history of asthma', 'concept_id': 'C0455544', 'confidence': 0.8792974948883057}], [{'entity': 'bone marrow', 'concept_id': 'C0005953', 'confidence': 1.0}, {'entity': 'trilinear hematopoiesis', 'concept_id': 'C0018951', 'confidence': 0.7991899251937866}, {'entity': 'normal cellularity', 'concept_id': 'C0178539', 'confidence': 0.8253751993179321}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "608.0",
"id": "test_572",
"caption_rating": "8"
},
{
"": "1007220",
"caption": "Two distinct morphologic populations of melanocytes, some dendritic and others spindle-shaped or fusiform-shaped.",
"image_path": "8S4LeiO6Bbk_image_38e60f68-290e-4146-add5-b6c842bcc610.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['dendritic', 'spindle-shaped', 'heavily pigmented melanophages', 'dendritic', 'spindle-shaped', 'intersecting vessels', 'combined melanocytic nevus', 'blue nevus']",
"noisy_text": " pairs. In the central portion of the specimen, you can see that the dermis is a little more sclerotic. And we've got the presence of separately heavily pigmented melanovagias. And then if we look at our top piece of tissue, again, we have the more banal appearing melanocytes out of the periphery. And centrally, we've got embedded within a sclerotic stroma a second distinct morphologic population of melanocytes. Some of these are dendritic, others have spindled or fusiform-shaped nuclei. They're arranged in short, intersecting vascals. And in between the dendritic and spindled melanocytes, we have very heavily pigmented melanovagias, all set in a sclerotic stroma. So basically, we have here a combined melanocytic nevus, one that has features of both a common or banal nevus and a blue nevus. And this",
"corrected_text": " pairs. In the central portion of the specimen, you can see that the dermis is a little more sclerotic. And we've got the presence of separately heavily pigmented melanovagias. And then if we look at our top piece of tissue, again, we have the more banal appearing melanocytes out of the periphery. And centrally, we've got embedded within a sclerotic stroma a second distinct morphologic population of melanocytes. Some of these are dendritic, others have spindle-shaped or fusiform-shaped cells. They're arranged in short, intersecting vessels. And in between the dendritic and spindle-shaped melanocytes, we have very heavily pigmented melanovagias, all set in a sclerotic stroma. So basically, we have here a combined melanocytic nevus, one that has features of both a common or banal nevus and a blue nevus. And this",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'heavily', 'concept_id': 'C0337678', 'confidence': 0.6902515292167664}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'melanophages', 'concept_id': 'C3280463', 'confidence': 0.9375340938568115}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}], [{'entity': 'morphologic populations', 'concept_id': 'C0032659', 'confidence': 0.6858205199241638}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'dendritic', 'concept_id': 'C0011305', 'confidence': 1.0}, {'entity': 'spindle-shaped', 'concept_id': 'C4230397', 'confidence': 0.9035798907279968}, {'entity': 'fusiform-shaped', 'concept_id': 'C0332493', 'confidence': 0.6468937397003174}], [{'entity': 'Arranged', 'concept_id': 'C1546854', 'confidence': 1.0}, {'entity': 'short', 'concept_id': 'C1282927', 'confidence': 1.0}, {'entity': 'intersecting vessels', 'concept_id': 'C0005847', 'confidence': 0.7007781863212585}], [{'entity': 'Combined', 'concept_id': 'C0205195', 'confidence': 1.0}, {'entity': 'melanocytic nevus', 'concept_id': 'C0027962', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'benign nevus', 'concept_id': 'C1456781', 'confidence': 1.0}, {'entity': 'blue nevus', 'concept_id': 'C0206736', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_573",
"caption_rating": "9"
},
{
"": "1006506",
"caption": "The glands are shortened and there is crypt shortening, with space between the muscularis mucosa and the bottom of the gland and the crypt. There is also basal lymphoplasmacytosis with eosinophils.",
"image_path": "sDFjOtMAYrk_image_61773244-773e-4114-bcac-de7e33a11fef.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['Glands with crypt shortening', 'Space between muscularis mucosa and bottom of gland and crypt', 'Basal lymphoplasmacytosis with eosinophils', 'Glands with crypt shortening', 'Space between muscularis mucosa and bottom of gland and crypt', 'Basal lymphoplasmacytosis with eosinophils']",
"noisy_text": " you're right. If you're wrong, you're wrong, and that's fine. Yes, yes. Yeah, so you think there's some crip dropout. I think you're right. What else? What would you say about the glands themselves? I would say they're a little bit shortened. So, compared to the normal case that I showed before, here's the muscularis mucosa, and here's the bottom of your gland, and there's a lot of space in between the muscularis mucosa and the bottom of the gland and the crypt. So, we would call that crip shortening. If you look closely, you'll see some basal lymphoplasma cytosis that includes some eosinophils. So, the other trich I like to use, and I heard this from Dr. Appelman",
"corrected_text": " you're right. If you're wrong, you're wrong, and that's fine. Yes, yes. Yeah, so you think there's some crip dropout. I think you're right. What else? What would you say about the glands themselves? I would say they're a little bit shortened. So, compared to the normal case that I showed before, here's the muscularis mucosa, and here's the bottom of your gland, and there's a lot of space in between the muscularis mucosa and the bottom of the gland and the crypt. So, we would call that crip shortening. If you look closely, you'll see some basal lymphoplasma cytosis that includes some eosinophils. So, the other trich I like to use, and I heard this from Dr. Appelman",
"med_umls_ids": "[[{'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'shortened', 'concept_id': 'C1282927', 'confidence': 1.0}, {'entity': 'crypt', 'concept_id': 'C1880192', 'confidence': 1.0}, {'entity': 'shortening', 'concept_id': 'C0441636', 'confidence': 1.0}, {'entity': 'muscularis mucosa', 'concept_id': 'C0225357', 'confidence': 0.9999998807907104}, {'entity': 'gland', 'concept_id': 'C1285092', 'confidence': 1.0}, {'entity': 'crypt', 'concept_id': 'C1880192', 'confidence': 1.0}, {'entity': 'basal lymphoplasmacytosis', 'concept_id': 'C0024419', 'confidence': 0.7173169851303101}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_574",
"caption_rating": "9"
},
{
"": "1008178",
"caption": "Coalescence of remnant cell walls of adipocytes seen at the periphery of the fat microcysts.",
"image_path": "hoV-JkD6Wb0_image_4a527a05-1434-4bf5-a26a-6d9a6454057f.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['Large fat microcysts', 'Membranous lipodystrophy at the periphery of the fat microcysts', 'Arabesque-type fibular material at the periphery of the fat microcysts', 'Remnant cell walls of adipocytes at the periphery of the fat microcysts', 'Large fat microcysts', 'Membranous lipodystrophy at the periphery of the fat microcysts', 'Arabesque-type fibular material at the periphery of the fat microcysts', 'Remnant cell walls of adipocytes at the periphery of the fat microcysts']",
"noisy_text": " inflammation. There aren't many viable adipocytes left here. A lot of the adipocytes have kind of ruptured and fused, and so we've got these large fat microcysts, and if we look at the periphery of the fat microcyst, we've got this lipomembranous change, this kind of arabesque-type fibular material out at the periphery, which basically represents coalescence of remnant cell walls of adipocytes. In addition, within the surrounding tissue, there's a little bit of fibrosis. There are a few lipophages and a very sparse infiltrative",
"corrected_text": " inflammation. There aren't many viable adipocytes left here. A lot of the adipocytes have kind of ruptured and fused, and so we've got these large fat microcysts, and if we look at the periphery of the fat microcyst, we've got this lipomembranous change, this kind of arabesque-type fibular material out at the periphery, which basically represents coalescence of remnant cell walls of adipocytes. In addition, within the surrounding tissue, there's a little bit of fibrosis. There are a few lipophages and a very sparse infiltrative",
"med_umls_ids": "[[{'entity': 'Inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}], [{'entity': 'adipocytes', 'concept_id': 'C0206131', 'confidence': 1.0}, {'entity': 'left', 'concept_id': 'C0205091', 'confidence': 1.0}], [{'entity': 'fat microcysts', 'concept_id': 'C1513269', 'confidence': 0.871767520904541}], [{'entity': 'Membranous lipodystrophy', 'concept_id': 'C0406599', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'fat microcysts', 'concept_id': 'C1513269', 'confidence': 0.871767520904541}], [{'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'fat microcysts', 'concept_id': 'C1513269', 'confidence': 0.871767520904541}], [{'entity': 'Coalescence', 'concept_id': 'C4727092', 'confidence': 0.8749340176582336}, {'entity': 'remnant', 'concept_id': 'C3272697', 'confidence': 1.0}, {'entity': 'cell walls', 'concept_id': 'C0007623', 'confidence': 1.0}, {'entity': 'adipocytes', 'concept_id': 'C0206131', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'fat microcysts', 'concept_id': 'C1513269', 'confidence': 0.871767520904541}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_575",
"caption_rating": "8"
},
{
"": "1006485",
"caption": "Granulation tissue is important in the healing process and consists of fibroblasts, myofibroblasts, inflammatory cells, and capillaries.",
"image_path": "rHSTVT91c8Q_image_354056aa-60da-450a-b97e-07fcfacb607a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Cardiac', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['granulation tissue', 'fibroblasts', 'myofibroblasts', 'inflammatory cells', 'capillaries', 'granulation tissue', 'fibroblasts', 'myofibroblasts', 'inflammatory cells', 'capillaries', 'granulation tissue', 'fibroblasts', 'myofibroblasts', 'inflammatory cells', 'capillaries']",
"noisy_text": " Here we see granulation tissue. Granulation tissue is very important in the healing process. It is basically the way how the organism creates a new connective tissue. So if you cut yourself the wound will be filled with granulation tissue. Another example is myocardial infarction where necrosis or coagulative necrosis after some time will turn into granulation tissue and over the time it will heal and create scar tissue. So granulation tissue consists of fibroblasts, myofibroblasts, inflammatory cells and capillaries. So a few capillaries can be seen here. They",
"corrected_text": " Here we see granulation tissue. Granulation tissue is very important in the healing process. It is basically the way how the organism creates a new connective tissue. So if you cut yourself the wound will be filled with granulation tissue. Another example is myocardial infarction where necrosis or coagulative necrosis after some time will turn into granulation tissue and over the time it will heal and create scar tissue. So granulation tissue consists of fibroblasts, myofibroblasts, inflammatory cells and capillaries. So a few capillaries can be seen here. They",
"med_umls_ids": "[[{'entity': 'Granulation tissue', 'concept_id': 'C0018180', 'confidence': 1.0}, {'entity': 'healing', 'concept_id': 'C0043240', 'confidence': 1.0}, {'entity': 'process', 'concept_id': 'C1184743', 'confidence': 1.0}, {'entity': 'fibroblasts', 'concept_id': 'C0016030', 'confidence': 1.0}, {'entity': 'myofibroblasts', 'concept_id': 'C0225360', 'confidence': 1.0}, {'entity': 'inflammatory cells', 'concept_id': 'C0440752', 'confidence': 1.0}, {'entity': 'capillaries', 'concept_id': 'C0006901', 'confidence': 0.9999998807907104}], [{'entity': 'Capillaries', 'concept_id': 'C0006901', 'confidence': 0.9999998807907104}, {'entity': 'tissue section', 'concept_id': 'C2316368', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_576",
"caption_rating": "8"
},
{
"": "1007225",
"caption": "Metaplasia of the gastric mucosa in the body of the stomach.",
"image_path": "r7OA0Trj5hQ_image_dcd6971f-f861-486d-b872-e949ad5938df.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['gastric mucosa', 'body of the stomach', 'peritoneal cells', 'mucincycletine cells', 'chief cells', 'pyloric metaplasia', 'autoimmune gastritis']",
"noisy_text": " metaplasia of the gastric mucosa. Here the history is this biopsy is taken from the body of the stomach. In the body of the stomach, you have to see a lot of fried eggs. These are all the peritoneal cells in addition to mucincycletine cells and chief cells. These are the peritoneal cells. When you don't see the peritoneal cells in the gastric fundic mucosa or gastric corpus mucosa, then you have to call it as pyloric metaplasia. This is very, very important because you see it in autoimmune gastritis. Sometimes the",
"corrected_text": " metaplasia of the gastric mucosa. Here the history is this biopsy is taken from the body of the stomach. In the body of the stomach, you have to see a lot of fried eggs. These are all the peritoneal cells in addition to mucincycletine cells and chief cells. These are the peritoneal cells. When you don't see the peritoneal cells in the gastric fundic mucosa or gastric corpus mucosa, then you have to call it as pyloric metaplasia. This is very, very important because you see it in autoimmune gastritis. Sometimes the",
"med_umls_ids": "[[{'entity': 'Metaplasia', 'concept_id': 'C0025568', 'confidence': 1.0}, {'entity': 'gastric mucosa', 'concept_id': 'C0017136', 'confidence': 1.0}, {'entity': 'body', 'concept_id': 'C0227230', 'confidence': 1.0}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'peritoneal cells', 'concept_id': 'C0031153', 'confidence': 0.7749612331390381}, {'entity': 'mucincycletine cells', 'concept_id': 'C0007586', 'confidence': 0.6177586317062378}, {'entity': 'chief cells', 'concept_id': 'C1516470', 'confidence': 1.0}], [{'entity': 'Absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'peritoneal cells', 'concept_id': 'C0031153', 'confidence': 0.7749612331390381}, {'entity': 'gastric fundic mucosa', 'concept_id': 'C0017136', 'confidence': 0.8429272770881653}, {'entity': 'gastric corpus mucosa', 'concept_id': 'C0735811', 'confidence': 0.9813486337661743}, {'entity': 'pyloric metaplasia', 'concept_id': 'C4288813', 'confidence': 0.8951747417449951}], [{'entity': 'Pyloric metaplasia', 'concept_id': 'C4288813', 'confidence': 0.8951747417449951}, {'entity': 'autoimmune gastritis', 'concept_id': 'C3887639', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_577",
"caption_rating": "8"
},
{
"": "1005728",
"caption": "Description of normal colonic glands and crypts with no lymphocytes, plasma cells, or eosinophils. The amount of lamina propria in between the crypts is the same as you move from one crypt to another.",
"image_path": "sDFjOtMAYrk_image_b87f929a-aac9-4a8b-85ca-8cf97a695c44.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['colonic crypts', 'muscularis mucosa', 'lamina propria']",
"noisy_text": " fellows about normal. What I like to see are these colonic glands. Do we have an arrow? Oh, yes. It should. Is he not coming up? No. Oh, you have to turn it on. No, it's not coming up. Yeah, it is. Yeah, here you go. Just the red one. Yeah. Oh, I don't see it. It's okay. Is the mouse going to work? Yeah, I'll do the mouse. Yeah, it works. Okay. Basically, I like to see my colonic crypts nice and straight coming from the surface, trying to kiss that muscularis mucosa underneath in between the crypts and the muscularis mucosa. I don't want to see any lymphocytes, plasma cells, eosinophils. You can have one or two. That's okay, but typically no basal lymphoplasma cytosis. The other thing I like to point out is the amount of lamina propria in between the crypts is the same as you move from one crypt to another. The crypts stand equidistant one from another. Remember the differences between the cecum or the right colon and the left colon. This is a biopsy from the segment and shows",
"corrected_text": " fellows about normal. What I like to see are these colonic glands. Do we have an arrow? Oh, yes. It should. Is he not coming up? No. Oh, you have to turn it on. No, it's not coming up. Yeah, it is. Yeah, here you go. Just the red one. Yeah. Oh, I don't see it. It's okay. Is the mouse going to work? Yeah, I'll do the mouse. Yeah, it works. Okay. Basically, I like to see my colonic crypts nice and straight coming from the surface, trying to kiss that muscularis mucosa underneath in between the crypts and the muscularis mucosa. I don't want to see any lymphocytes, plasma cells, eosinophils. You can have one or two. That's okay, but typically no basal lymphoplasma cytosis. The other thing I like to point out is the amount of lamina propria in between the crypts is the same as you move from one crypt to another. The crypts stand equidistant one from another. Remember the differences between the cecum or the right colon and the left colon. This is a biopsy from the segment and shows",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'colonic glands', 'concept_id': 'C0227351', 'confidence': 0.8191195130348206}, {'entity': 'crypts', 'concept_id': 'C0227427', 'confidence': 0.9071587324142456}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'amount', 'concept_id': 'C1265611', 'confidence': 0.9999998807907104}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'crypts', 'concept_id': 'C0227427', 'confidence': 0.9071587324142456}, {'entity': 'crypt', 'concept_id': 'C1880192', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_578",
"caption_rating": "8"
},
{
"": "1005907",
"caption": "Superficial injury with relatively preserved bottom crypts is indicative of ischemia.",
"image_path": "sDFjOtMAYrk_image_758b068d-b34c-4077-8fb4-8c75d5ed190d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "[]",
"noisy_text": " what you see in patients with ischemia. So basically, injury that's predominantly superficial with relative preservation of the bottom crypts. Very hyaluronized lamina propria when the ischemia has been ongoing for a while. It may or may not be there when the ischemia has been short-lived. Here you can see very nicely the superficial injury with relatively preserved bottoms. I find the cytologic atypia really helpful when I'm dealing with cases where I really don't know what's going on. I've caught maybe one or two cases of patients with subclinical very mild level ischemia that the only finding was just the cytologic atypia that I don't know where it's really coming from. And I'll show a case down the road. Actually, I'll show it right now. So this is a patient who I don't really remember the clinical history. I just thought, I mean, the architecture",
"corrected_text": " what you see in patients with ischemia. So basically, injury that's predominantly superficial with relative preservation of the bottom crypts. Very hyalinized lamina propria when the ischemia has been ongoing for a while. It may or may not be there when the ischemia has been short-lived. Here you can see very nicely the superficial injury with relatively preserved bottoms. I find the cytologic atypia really helpful when I'm dealing with cases where I really don't know what's going on. I've caught maybe one or two cases of patients with subclinical very mild level ischemia that the only finding was just the cytologic atypia that I don't know where it's really coming from. And I'll show a case down the road. Actually, I'll show it right now. So this is a patient who I don't really remember the clinical history. I just thought, I mean, the architecture",
"med_umls_ids": "[[{'entity': 'Superficial injury', 'concept_id': 'C0332671', 'confidence': 1.0}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}], [{'entity': 'Hyalinized lamina propria', 'concept_id': 'C0332230', 'confidence': 0.7577076554298401}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}], [{'entity': 'Cytologic atypia', 'concept_id': 'C0333865', 'confidence': 1.0}, {'entity': 'finding', 'concept_id': 'C0037088', 'confidence': 1.0}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'mild', 'concept_id': 'C1513302', 'confidence': 1.0}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_579",
"caption_rating": "8"
},
{
"": "1004169",
"caption": "The stain worked because the melanocytes in the positive control were stained dark brown.",
"image_path": "8S4LeiO6Bbk_image_9cbe2dc8-5cb5-493d-ad87-708268ed80cb.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['melanocytes', 'melanocytic nevus', 'melanocytes', 'tissue sample']",
"noisy_text": " with that being said, we'll go ahead and move on to slide number two, which was a melanin A or Mk1 immunohistochemical stain of this same piece of tissue. Underneath this bubble here we have our control. This is a melanocytic nevus and we can see in this positive control indeed the stain was working because the melanocytes are stained dark brown. So if we go up and take a look at the biopsy specimen, the tissue in question, I'm going to rotate the slide a little bit. And what we want to focus on",
"corrected_text": " with that being said, we'll go ahead and move on to slide number two, which was a melanin A or Mk1 immunohistochemical stain of this same piece of tissue. Underneath this bubble here we have our control. This is a melanocytic nevus and we can see in this positive control indeed the stain was working because the melanocytes are stained dark brown. So if we go up and take a look at the biopsy specimen, the tissue in question, I'm going to rotate the slide a little bit. And what we want to focus on",
"med_umls_ids": "[[{'entity': 'Melanin A', 'concept_id': 'C0025196', 'confidence': 0.8931530714035034}, {'entity': 'Mk1', 'concept_id': 'C1708816', 'confidence': 1.0}, {'entity': 'immunohistochemical stain', 'concept_id': 'C4317108', 'confidence': 0.9572635889053345}, {'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}], [{'entity': 'melanocytic nevus', 'concept_id': 'C0027962', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}], [{'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'positive control', 'concept_id': 'C1883676', 'confidence': 1.0}, {'entity': 'stained dark brown', 'concept_id': 'C4047948', 'confidence': 0.7432422637939453}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_580",
"caption_rating": "8"
},
{
"": "1005789",
"caption": "The tissue being examined is elastic cartilage, which is characterized by the presence of lacunas and chondrocytes.",
"image_path": "ib991vTA67A_image_16aa5ee3-f5c4-4aca-9da4-3d65198defc4.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Head and Neck']",
"roi_text": "['elastic cartilage', 'lacunas', 'chondrocytes', 'external ear', 'epiglottis', 'reticular connective tissue', 'epithelial tissue']",
"noisy_text": " the answer, this is elastic cartilage, you know it's a cartilage because you see the lacunas, so this is lacuna right here with the chondrocyte in it, where do you find elastic cartilage, think of the E's, elastic cartilage, external ear and the epiglottis, so elastic cartilage, external ear, epiglottis, that's where you're going to find elastic cartilage, that was number nineteen, number twenty, where do you, see this is a reticular connective tissue again, where do you find it, underneath all epithelial tissue, underneath all epithelial tissue, remember",
"corrected_text": " the answer, this is elastic cartilage, you know it's a cartilage because you see the lacunas, so this is lacuna right here with the chondrocyte in it, where do you find elastic cartilage, think of the E's, elastic cartilage, external ear and the epiglottis, so elastic cartilage, external ear, epiglottis, that's where you're going to find elastic cartilage, that was number nineteen, number twenty, where do you, see this is a reticular connective tissue again, where do you find it, underneath all epithelial tissue, underneath all epithelial tissue, remember",
"med_umls_ids": "[[{'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'examined', 'concept_id': 'C0332128', 'confidence': 1.0}, {'entity': 'elastic cartilage', 'concept_id': 'C0682559', 'confidence': 0.9999998807907104}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lacunas', 'concept_id': 'C1459585', 'confidence': 0.8563621044158936}, {'entity': 'chondrocytes', 'concept_id': 'C0225369', 'confidence': 1.0}], [{'entity': 'Elastic cartilage', 'concept_id': 'C0682559', 'confidence': 0.9999998807907104}, {'entity': 'external ear', 'concept_id': 'C0013453', 'confidence': 1.0}, {'entity': 'epiglottis', 'concept_id': 'C0014540', 'confidence': 0.9999999403953552}], [{'entity': 'Reticular', 'concept_id': 'C0439739', 'confidence': 1.0}, {'entity': 'connective tissue', 'concept_id': 'C0009780', 'confidence': 1.0}, {'entity': 'epithelial tissue', 'concept_id': 'C0014609', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1152.0",
"id": "test_581",
"caption_rating": "8"
},
{
"": "1009137",
"caption": "Hyalinization or sclerosis around vessels can occur, which is characterized by collagen deposition and can make vessels stand out as pink.",
"image_path": "QDb68_G1HR4_image_2ee42782-6dd9-4b6a-a5ea-0cd69691d5c1.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Hyalinization or sclerosis around vessels in the highlighted area.']",
"noisy_text": " And again I mentioned that you can have some hyalinization or sclerosis around vessels and here's a here's a nice example of that. You can see over over here in this area you can really nicely see that these these pink circle standing out. These are vessels and you can really appreciate the arch shape here this nice curved arch little hook of a vessel and there's so much collagen around the vessels it really makes them stand out as pink it's really a really dramatic pattern in this case. So very hyalinized kind of pink stuff that it's so dense that you can not really even appreciate the",
"corrected_text": " And again I mentioned that you can have some hyalinization or sclerosis around vessels and here's a here's a nice example of that. You can see over over here in this area you can really nicely see that these these pink circle standing out. These are vessels and you can really appreciate the arch shape here this nice curved arch little hook of a vessel and there's so much collagen around the vessels it really makes them stand out as pink it's really a really dramatic pattern in this case. So very hyalinized kind of pink stuff that it's so dense that you can not really even appreciate the",
"med_umls_ids": "[[{'entity': 'Hyalinization', 'concept_id': 'C0333438', 'confidence': 1.0}, {'entity': 'sclerosis', 'concept_id': 'C0036429', 'confidence': 1.0}, {'entity': 'vessels', 'concept_id': 'C0005847', 'confidence': 1.0}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'deposition', 'concept_id': 'C0333562', 'confidence': 1.0}, {'entity': 'vessels', 'concept_id': 'C0005847', 'confidence': 1.0}, {'entity': 'pink', 'concept_id': 'C0332585', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_582",
"caption_rating": "8"
},
{
"": "1006344",
"caption": "Intraductal carcinoma of the prostate is usually due to invasion, colonization by adjacent invasive tumor.",
"image_path": "iklRyY1nBIE_image_e5344b6f-b392-4d71-97ae-d049d4f28d8f.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['basal cells at the periphery', 'enlarged nuclei', 'intraductal carcinoma of the prostate', 'adjacent invasive tumor', 'previously benign gland', 'basal cells at the periphery', 'enlarged nuclei', 'intraductal carcinoma of the prostate', 'adjacent invasive tumor', 'previously benign gland']",
"noisy_text": " Let me show you what the cocktail looks like. Again, this is the pin three, or some call it pin four. You have the P63, you have the hemoglobin cytokeratin, and then you have the racemase, which is the pink chromogen. And as you can see, as I demonstrated on the H&E, basal cells are indeed present. This is too much for high-grade pin. This is basically what is called a solid cribriform kind of pattern, in which over 50% of the lumen is filled by tumor cells. So this is way too much for high-grade pin. But it's not invasive, because you have basal cells at the periphery. And the nuclei are enlarged. These nuclei are about six times the size of normal prostate nuclei. So this case meets the criteria for introductal carcinoma of the prostate. There is an invasive component, which you can see is negative for basal cell markers. But you have the introductal component. And this is a very interesting entity. The vast majority of cases, and I'll show you the corresponding radical prostatectomy specimens in a second, but the vast majority of these so-called introductal carcinoma of the prostate is due to invasion, colonization by adjacent invasive tumor. And it usually occurs in patients that have high-volume tumors. When I show you the corresponding radical prostatectomies, you'll see what I'm talking about. You usually don't have this in patients in their radicals that have 5% prostate cancer or 10% prostate cancer. It's usually patients that have extensive prostate cancer involvement, and the invasive glands basically have nowhere else to go but to colonize adjacent benign glands. And I'll demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues,",
"corrected_text": " Let me show you what the cocktail looks like. Again, this is the pin three, or some call it pin four. You have the P63, you have the hemoglobin cytokeratin, and then you have the racemase, which is the AMACR. And as you can see, as I demonstrated on the H&E, basal cells are indeed present. This is too much for high-grade pin. This is basically what is called a solid cribriform kind of pattern, in which over 50% of the lumen is filled by tumor cells. So this is way too much for high-grade pin. But it's not invasive, because you have basal cells at the periphery. And the nuclei are enlarged. These nuclei are about six times the size of normal prostate nuclei. So this case meets the criteria for intraductal carcinoma of the prostate. There is an invasive component, which you can see is negative for basal cell markers. But you have the intraductal component. And this is a very interesting entity. The vast majority of cases, and I'll show you the corresponding radical prostatectomy specimens in a second, but the vast majority of these so-called intraductal carcinoma of the prostate is due to invasion, colonization by adjacent invasive tumor. And it usually occurs in patients that have high-volume tumors. When I show you the corresponding radical prostatectomies, you'll see what I'm talking about. You usually don't have this in patients in their radicals that have 5% prostate cancer or 10% prostate cancer. It's usually patients that have extensive prostate cancer involvement, and the invasive glands basically have nowhere else to go but to colonize adjacent benign glands. And I'demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues,",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'cocktail', 'concept_id': 'C0678420', 'confidence': 1.0}, {'entity': 'markers', 'concept_id': 'C0181734', 'confidence': 0.890313982963562}, {'entity': 'intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate diagnosis', 'concept_id': 'C0011900', 'confidence': 0.7927443981170654}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'basal cells', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}], [{'entity': 'Enlarged nuclei', 'concept_id': 'C4013177', 'confidence': 0.7774685621261597}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'normal', 'concept_id': 'C0205307', 'confidence': 1.0}], [{'entity': 'Intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'invasion', 'concept_id': 'C1269955', 'confidence': 1.0}, {'entity': 'colonization', 'concept_id': 'C4289767', 'confidence': 1.0}, {'entity': 'adjacent', 'concept_id': 'C0205117', 'confidence': 1.0}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}], [{'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'benign gland', 'concept_id': 'C0205183', 'confidence': 0.7986565828323364}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_583",
"caption_rating": "7"
},
{
"": "1009453",
"caption": "The tumor was previously described as a hyalinizing spindle cell tumor with giant rosettes.",
"image_path": "QDb68_G1HR4_image_c225f0f2-ac45-4685-aa17-97910ae9fdc4.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " So this tumor has been in the past described as hyalinizing spindle cell tumor with giant rosettes and we now recognize and have immunohistochemical and molecular proof that this is just a morphologic variation of low-grade fibromyxoid sarcoma so I'll still mention this oftentimes in the report just as a kind of a comment that this tumor has the unique pattern of hyalinizing spindle cell tumor with giant rosettes but in my line diagnosis I would still call this low-grade fibromyxoid sarcoma because it is low-grade fibromyxoid and look again how dense the collagen is in this area this is that sclerotic kind of area really has almost like a tiger",
"corrected_text": " So this tumor has been in the past described as hyalinizing spindle cell tumor with giant rosettes and we now recognize and have immunohistochemical and molecular proof that this is just a morphologic variation of low-grade fibromyxoid sarcoma so I'll still mention this oftentimes in the report just as a kind of a comment that this tumor has the unique pattern of hyalinizing spindle cell tumor with giant rosettes but in my line diagnosis I would still call this low-grade fibromyxoid sarcoma because it is low-grade fibromyxoid and look again how dense the collagen is in this area this is that sclerotic kind of area really has almost like a tiger",
"med_umls_ids": "[[{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'hyalinizing', 'concept_id': 'C0332230', 'confidence': 1.0}, {'entity': 'giant', 'concept_id': 'C0017547', 'confidence': 1.0}, {'entity': 'rosettes', 'concept_id': 'C0035863', 'confidence': 0.8847858905792236}], [{'entity': 'morphologic', 'concept_id': 'C0543482', 'confidence': 0.9229367971420288}, {'entity': 'variation', 'concept_id': 'C0205419', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}], [{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'unique', 'concept_id': 'C1710548', 'confidence': 1.0}, {'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}, {'entity': 'hyalinizing', 'concept_id': 'C0332230', 'confidence': 1.0}, {'entity': 'giant', 'concept_id': 'C0017547', 'confidence': 1.0}, {'entity': 'rosettes', 'concept_id': 'C0035863', 'confidence': 0.8847858905792236}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_584",
"caption_rating": "9"
},
{
"": "1007602",
"caption": "The cornified layer appears thickened in this case.",
"image_path": "8S4LeiO6Bbk_image_8735b46d-df9d-4706-a284-4fdabb7c7d9d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Uniform spindle-shaped cells in the dermis with elongated and tapered nuclei and indistinct cytoplasmic margins', 'Thickened cornified layer', 'Slightly thinned epidermis with a basement of the reed bridge pattern', 'Uniform spindle-shaped cells in the dermis with elongated and tapered nuclei and indistinct cytoplasmic margins', 'Crisscross configuration of fascicles throughout the dermis', 'Thickened cornified layer', 'Slightly thinned epidermis with a basement of the reed bridge pattern', 'Uniform spindle-shaped cells in the dermis with elongated and tapered nuclei and indistinct cytoplasmic margins', 'Crisscross configuration of fascicles throughout the dermis']",
"noisy_text": " kind of relegated to do in this case, we can see that the cornified layer is somewhat thickened. This biopsy was from near an acral surface. This was from the finger. You can see that the epidermis is slightly thinned with the basement of the reed bridge pattern, and then filling the dermis in this case, we have fascicles of uniform spindle-shaped cells. You can see that their nuclei are elongated and tapered. The cytoplasmic margins of these cells are somewhat indistinct. They do have somewhat elongated cytoplasmic processes, and there are a range of fascicles. Some of the fascicles are cut in cross-section. Here you can see the nuclei appear more round. Some are cut longitudinally, and that's where we see the very elongated nuclei and cytoplasmic processes, and some are cut tangentially. This gives these fascicles kind of a crisscross configuration throughout the dermis. Hopefully, you all were able to pick up on the diagnostic feature in",
"corrected_text": " kind of relegated to do in this case, we can see that the cornified layer is somewhat thickened. This biopsy was from near an acral surface. This was from the finger. You can see that the epidermis is slightly thinned with the basement of the reed bridge pattern, and then filling the dermis in this case, we have fascicles of uniform spindle-shaped cells. You can see that their nuclei are elongated and tapered. The cytoplasmic margins of these cells are somewhat indistinct. They do have somewhat elongated cytoplasmic processes, and there are a range of fascicles. Some of the fascicles are cut in cross-section. Here you can see the nuclei appear more round. Some are cut longitudinally, and that's where we see the very elongated nuclei and cytoplasmic processes, and some are cut tangentially. This gives these fascicles kind of a crisscross configuration throughout the dermis. Hopefully, you all were able to pick up on the diagnostic feature in",
"med_umls_ids": "[[{'entity': 'cornified layer', 'concept_id': 'C3554359', 'confidence': 0.8562335968017578}, {'entity': 'thickened', 'concept_id': 'C0205400', 'confidence': 1.0}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}], [{'entity': 'epidermis', 'concept_id': 'C0014520', 'confidence': 1.0}, {'entity': 'thinned', 'concept_id': 'C0392758', 'confidence': 1.0}, {'entity': 'basement', 'concept_id': 'C0085872', 'confidence': 0.772655725479126}, {'entity': 'reed', 'concept_id': 'C0681191', 'confidence': 0.7412400841712952}], [{'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'fascicles', 'concept_id': 'C1185741', 'confidence': 1.0}, {'entity': 'uniform', 'concept_id': 'C0205375', 'confidence': 1.0}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}, {'entity': 'elongated', 'concept_id': 'C0205166', 'confidence': 1.0}, {'entity': 'tapered', 'concept_id': 'C0441640', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'indistinct cytoplasmic margins', 'concept_id': 'C4323148', 'confidence': 0.6683960556983948}], [{'entity': 'fascicles', 'concept_id': 'C1185741', 'confidence': 1.0}, {'entity': 'crisscross configuration', 'concept_id': 'C0449830', 'confidence': 0.7424066066741943}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_585",
"caption_rating": "8"
},
{
"": "1004898",
"caption": "The tissue sample contains nail bed and matrix epithelium.",
"image_path": "8S4LeiO6Bbk_image_0745588b-e17e-42b4-a6c0-d598f293a979.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['nail bed', 'matrix epithelium', 'melanocytes forming nests', 'pagetoid pattern', 'basal layer of the matrix', 'upper portions of the matrix']",
"noisy_text": " we've got nail bed and matricle epithelium. I believe this must be some nail fold, a portion of the nail fold, and then in the bottom piece of tissue in these sections we actually have matricle epithelium and you can see the rete or somewhat hyperplastic. And on higher power examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matricle epithelium in the matricle layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that",
"corrected_text": " we've got nail bed and matrix epithelium. I believe this must be some nail fold, a portion of the nail fold, and then in the bottom piece of tissue in these sections we actually have matrix epithelium and you can see the rete or somewhat hyperplastic. And on higher power examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matrix epithelium in the matrix layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that",
"med_umls_ids": "[[{'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'nail', 'concept_id': 'C0027342', 'confidence': 1.0}, {'entity': 'matrix epithelium', 'concept_id': 'C0014609', 'confidence': 0.7584323883056641}], [{'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'nests', 'concept_id': 'C0035253', 'confidence': 0.7275967001914978}, {'entity': 'upper portions', 'concept_id': 'C0449719', 'confidence': 0.6251541972160339}, {'entity': 'matrix', 'concept_id': 'C0331858', 'confidence': 1.0}, {'entity': 'pagetoid', 'concept_id': 'C1518847', 'confidence': 0.8801172375679016}, {'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}], [{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'matrix layer', 'concept_id': 'C0331858', 'confidence': 0.71736741065979}, {'entity': 'suspicious', 'concept_id': 'C0750493', 'confidence': 1.0}, {'entity': 'melanoma', 'concept_id': 'C0025202', 'confidence': 1.0}, {'entity': 'in situ', 'concept_id': 'C0444498', 'confidence': 0.9999999403953552}]]",
"magnification": "1.0",
"height": "758.0",
"width": "1920.0",
"id": "test_586",
"caption_rating": "8"
},
{
"": "1006206",
"caption": "The tumor is a Brenner borderline tumor because there is no invasion yet.",
"image_path": "3mRB9j0eyVM_image_f516f114-994a-4ab1-bef2-78a875e0b7ae.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gynecologic', 'Hematopathology', 'Soft tissue']",
"roi_text": "['papillary structures', 'transitional type cells', 'marked atypia', 'invasion in the ovarian stroma', 'cytoplasmic clearing', 'invasion in the ovarian stroma']",
"noisy_text": " tumor. Again here you can see the papillary structures that show stratification of the cells and the cells are of transitional type. So this is called Brenner borderline tumor because yet or still there is no invasion. When there is invasion of the cells here you can see there is marked ATPR in the urethelial cells or in the transitional cells and they show invasion in the ovarian stroma. Now it is named as malignant Brenner tumor or transitional cell carcinoma of the ovary. Here you can see this is the clear cell carcinoma of the ovary. You can well identify the cytoplasmic clearing these rounded clear structures cytoplasmic clearing of",
"corrected_text": " tumor. Again here you can see the papillary structures that show stratification of the cells and the cells are of transitional type. So this is called Brenner borderline tumor because yet or still there is no invasion. When there is invasion of the cells here you can see there is marked atypia in the urothelial cells or in the transitional cells and they show invasion in the ovarian stroma. Now it is named as malignant Brenner tumor or transitional cell carcinoma of the ovary. Here you can see this is the clear cell carcinoma of the ovary. You can well identify the cytoplasmic clearing these rounded clear structures cytoplasmic clearing of",
"med_umls_ids": "[[{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'Brenner borderline tumor', 'concept_id': 'C0334494', 'confidence': 0.9999999403953552}, {'entity': 'invasion', 'concept_id': 'C1269955', 'confidence': 1.0}], [{'entity': 'invasion', 'concept_id': 'C1269955', 'confidence': 1.0}, {'entity': 'malignant', 'concept_id': 'C0205282', 'confidence': 1.0}, {'entity': 'Brenner tumor', 'concept_id': 'C0006160', 'confidence': 1.0}, {'entity': 'transitional', 'concept_id': 'C1182674', 'confidence': 1.0}, {'entity': 'ovary', 'concept_id': 'C0029939', 'confidence': 1.0}], [{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'cell carcinoma', 'concept_id': 'C1518174', 'confidence': 1.0}, {'entity': 'ovary', 'concept_id': 'C0029939', 'confidence': 1.0}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'cytoplasmic clearing', 'concept_id': 'C0010834', 'confidence': 0.8013758659362793}]]",
"magnification": "2.0",
"height": "720.0",
"width": "960.0",
"id": "test_587",
"caption_rating": "8"
},
{
"": "1004710",
"caption": "Presence of nuclear and cytoplasmic inclusion indicating CMV infection which affects mesenchymal derived cells first, endothelial cells and fibroblasts leading to vasculitis and ischemia.",
"image_path": "r7OA0Trj5hQ_image_08a0696b-f13b-483a-9f96-dd735a161833.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['endothelial cells', 'vasculitis and ischemia', 'endothelial cells', 'vasculitis and ischemia', 'endothelial cells', 'vasculitis and ischemia']",
"noisy_text": " nuclear and cytoplasmic inclusion. These are CMV infection. These are all involving blood vessels. One thing for CMV, it affects mesenchymal derived cells first, endothelial cells and the fibroblasts. Since it's involving the endothelial cells, it produces vasculitis and ischemia. And that's why most of the CMV gastroenteropathy is associated with ischemic changes because of the overlapping vasculitis. Here, it is involving more epithelium. Whereas here, it's involving more endothelium. This is a special strain, gastric biopsy again. You see",
"corrected_text": " nuclear and cytoplasmic inclusion. These are CMV infection. These are all involving blood vessels. One thing for CMV, it affects mesenchymal derived cells first, endothelial cells and the fibroblasts. Since it's involving the endothelial cells, it produces vasculitis and ischemia. And that's why most of the CMV gastroenteropathy is associated with ischemic changes because of the overlapping vasculitis. Here, it is involving more epithelium. Whereas here, it's involving more endothelium. This is a special strain, gastric biopsy again. You see",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'nuclear', 'concept_id': 'C0521447', 'confidence': 1.0}, {'entity': 'cytoplasmic', 'concept_id': 'C0010834', 'confidence': 1.0}, {'entity': 'inclusion', 'concept_id': 'C0007637', 'confidence': 1.0}, {'entity': 'CMV infection', 'concept_id': 'C0010823', 'confidence': 1.0}, {'entity': 'mesenchymal', 'concept_id': 'C1513143', 'confidence': 1.0}, {'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'endothelial cells', 'concept_id': 'C0225336', 'confidence': 1.0}, {'entity': 'fibroblasts', 'concept_id': 'C0016030', 'confidence': 1.0}, {'entity': 'vasculitis', 'concept_id': 'C0042384', 'confidence': 1.0}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_588",
"caption_rating": "9"
},
{
"": "1007677",
"caption": "Different types of dermatofibroma, including those with large atypical cells or monster cells.",
"image_path": "udoW6VSqsm4_image_268d2681-a524-4a5c-90e3-dcda155aafed.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['hemosiderin areas', 'foamy areas', 'lipid-laden cells', 'cellular dermatofibroma', 'dermatofibroma with large atypical cells', 'dermatofibroma with monster cells']",
"noisy_text": " Like there are areas where there was hemosiderin. It's kind of hard to see from here, but I found some areas where there was hemosiderin, but some areas that were also a little foamy. Yeah, I'd say a little bit foamy. Scale of one to ten, that's probably about a ten with regard to foaming. So yeah, they're very lipidized. So this would be like a cellular dermatofibroma with lipidization. There's another type of dermatofibroma where you can see large atypical cells, or dermatofibroma with monster cells. Those can simulate cancer. This one didn't really have as many of those kinds of cells. Yeah, so",
"corrected_text": " Like there are areas where there was hemosiderin. It's kind of hard to see from here, but I found some areas where there was hemosiderin, but some areas that were also a little foamy. Yeah, I'd say a little bit foamy. Scale of one to ten, that's probably about a ten with regard to foaming. So yeah, they're very lipidized cells. So this would be like a cellular dermatofibroma with lipidization of cells. There's another type of dermatofibroma where you can see large atypical cells, or dermatofibroma with monster cells. Those can simulate cancer. This one didn't really have as many of those kinds of cells. Yeah, so",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'hemosiderin', 'concept_id': 'C0019113', 'confidence': 1.0}, {'entity': 'foamy', 'concept_id': 'C4523940', 'confidence': 0.8298001885414124}, {'entity': 'regions', 'concept_id': 'C0242961', 'confidence': 0.8140352964401245}], [{'entity': 'Cellular dermatofibroma', 'concept_id': 'C0002991', 'confidence': 0.833601713180542}, {'entity': 'lipid accumulation', 'concept_id': 'C0333574', 'confidence': 1.0}], [{'entity': 'dermatofibroma', 'concept_id': 'C0002991', 'confidence': 1.0}, {'entity': 'atypical cells', 'concept_id': 'C0333865', 'confidence': 1.0}, {'entity': 'monster cells', 'concept_id': 'C0007584', 'confidence': 0.7091032862663269}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_589",
"caption_rating": "7"
},
{
"": "1006586",
"caption": "The described tumor is a Brenner borderline tumor with papillary structures and transitional type cells, but no invasion yet.",
"image_path": "3mRB9j0eyVM_image_0c4179d7-d7df-4f7a-9edc-be70f039efe7.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gynecologic', 'Hematopathology', 'Soft tissue']",
"roi_text": "['ovary', 'Brenner tumor', 'ovary', 'transitional cell carcinoma', 'papillary structures', 'transitional type cells', 'invasion']",
"noisy_text": " in the ovary and they do not show invasion you will call that this is a benign Brenner tumor. But when these cells these show aggressive behavior, they show ATPR and they infiltrate ovarian stroma then it will be named as transitional cell carcinoma. This is Brenner borderline tumor. Again here you can see the papillary structures that show stratification of the cells and the cells are of transitional type. So this is called Brenner borderline tumor because yet or still there is no invasion. When there is invasion of the cells here you can see there is marked ATPR in the urethelial cells or in the transitional cells and they show invasion",
"corrected_text": " in the ovary and they do not show invasion you will call that this is a benign Brenner tumor. But when these cells these show aggressive behavior, they show ATPR and they infiltrate ovarian stroma then it will be named as transitional cell carcinoma. This is Brenner borderline tumor. Again here you can see the papillary structures that show stratification of the cells and the cells are of transitional type. So this is called Brenner borderline tumor because yet or still there is no invasion. When there is invasion of the cells here you can see there is marked ATPR in the urothelial cells or in the transitional cells and they show invasion",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'Brenner tumor', 'concept_id': 'C0006160', 'confidence': 1.0}, {'entity': 'ovary', 'concept_id': 'C0029939', 'confidence': 1.0}, {'entity': 'benign', 'concept_id': 'C0205183', 'confidence': 1.0}, {'entity': 'aggressive behavior', 'concept_id': 'C0001807', 'confidence': 1.0}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'transitional', 'concept_id': 'C1182674', 'confidence': 1.0}, {'entity': 'cell carcinoma', 'concept_id': 'C1518174', 'confidence': 1.0}], [{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'Brenner borderline tumor', 'concept_id': 'C0334494', 'confidence': 0.9999999403953552}, {'entity': 'papillary structures', 'concept_id': 'C0030352', 'confidence': 0.7890171408653259}, {'entity': 'transitional', 'concept_id': 'C1182674', 'confidence': 1.0}, {'entity': 'invasion', 'concept_id': 'C1269955', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "960.0",
"id": "test_590",
"caption_rating": "9"
},
{
"": "1004592",
"caption": "Increased melanin in the basilar keratinocytes.",
"image_path": "8S4LeiO6Bbk_image_9667fa36-5fd9-4553-9f8c-8b3cdac2b6c1.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Melanin granules within melanophages', 'Extravasated erythrocytes', 'Increased melanin in the basilar keratinocytes.', 'Melanin granules within melanophages', 'Extravasated erythrocytes', 'Increased melanin in the basilar keratinocytes.']",
"noisy_text": " or the melanophages is variable in size and shape. Now look at the melanin granules within this melanophage, and you can see that they're much more uniform in size and shape. Now look at the melanin granules within this melanophage, and you can see that they're much more uniform in size than the hemocentauric pigment in the centaurifages. It also tends to be a little bit darker staining, but sometimes it can be very difficult, tinctorially, depending upon the staining quality, to use color to distinguish the two, better to use size and context clues. Also note here we don't have any extravasated erythrocytes here, so much more likely to be melanin, and there's an increased melanin in the basilar keratinocytes. Getting back to the case, thin epidermis, bacular",
"corrected_text": " or the melanophages is variable in size and shape. Now look at the melanin granules within this melanophage, and you can see that they're much more uniform in size and shape. Now look at the melanin granules within this melanophage, and you can see that they're much more uniform in size than the hemosiderin pigment in the centroblasts. It also tends to be a little bit darker staining, but sometimes it can be very difficult, tinctorially, depending upon the staining quality, to use color to distinguish the two, better to use size and context clues. Also note here we don't have any extravasated erythrocytes here, so much more likely to be melanin, and there's an increased melanin in the basilar keratinocytes. Getting back to the case, thin epidermis, bacular",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'melanophages', 'concept_id': 'C3280463', 'confidence': 0.9375340938568115}, {'entity': 'variable size', 'concept_id': 'C1866144', 'confidence': 0.8559831976890564}, {'entity': 'shape', 'concept_id': 'C0332479', 'confidence': 1.0}], [{'entity': 'Melanin granules', 'concept_id': 'C0230692', 'confidence': 0.9174172878265381}, {'entity': 'melanophages', 'concept_id': 'C3280463', 'confidence': 0.9375340938568115}, {'entity': 'uniform', 'concept_id': 'C0205375', 'confidence': 1.0}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'shape', 'concept_id': 'C0332479', 'confidence': 1.0}, {'entity': 'hemosiderin', 'concept_id': 'C0019113', 'confidence': 1.0}, {'entity': 'pigment', 'concept_id': 'C0031911', 'confidence': 1.0}, {'entity': 'centroblasts', 'concept_id': 'C1517735', 'confidence': 0.8281925320625305}], [{'entity': 'Increased', 'concept_id': 'C0205217', 'confidence': 1.0}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}, {'entity': 'basilar keratinocytes', 'concept_id': 'C0022567', 'confidence': 0.803361713886261}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_591",
"caption_rating": "9"
},
{
"": "1009279",
"caption": "The inflammatory infiltrate includes lymphocytes and scattered eosinophils, with thickening or retention of the dermal papillae.",
"image_path": "hoV-JkD6Wb0_image_cfec72a9-a13d-4e4b-97e6-de1d7d2249dc.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['Subepidermal blister', 'Inflammatory cells in papillary dermis and blister cavity', 'Lymphocytes and scattered eosinophils', 'Thickening or retention of dermal papillae', 'Eosinophils, extravasated erythrocytes, lymphocytes, and neutrophils in blister cavity', 'Subepidermal blister', 'Inflammatory cells in papillary dermis and blister cavity', 'Lymphocytes and scattered eosinophils', 'Thickening or retention of dermal papillae', 'Eosinophils, extravasated erythrocytes, lymphocytes, and neutrophils in blister cavity']",
"noisy_text": " immunofluorescence. Let me flip the slide here. The staining, I'm sorry, is not so great, but one can see the presence of a subepidermal blister here. This is relatively cell-rich. There's fibrin and inflammatory cells in the papillary dermis and in the blister cavity. And if we look at the inflammatory infiltrate, there are lymphocytes and scattered eosinophils present within the dermis, some festooning or retention of the dermal papillae, and lots of eosinophils, some extravasated erythrocytes, lymphocytes, and a few neutrophils in the blister cavity. And so, you know,",
"corrected_text": " immunofluorescence. Let me flip the slide here. The staining, I'm sorry, is not so great, but one can see the presence of a subepidermal blister here. This is relatively cell-rich. There's fibrin and inflammatory cells in the papillary dermis and in the blister cavity. And if we look at the inflammatory infiltrate, there are lymphocytes and scattered eosinophils present within the dermis, some festooning or retention of the dermal papillae, and lots of eosinophils, some extravasated erythrocytes, lymphocytes, and a few neutrophils in the blister cavity. And so, you know,",
"med_umls_ids": "[[{'entity': 'subepidermal blister', 'concept_id': 'C1856956', 'confidence': 0.9338953495025635}, {'entity': 'cell-rich environment', 'concept_id': 'C0014406', 'confidence': 0.7375022768974304}, {'entity': 'fibrin', 'concept_id': 'C0015982', 'confidence': 1.0}, {'entity': 'inflammatory cells', 'concept_id': 'C0440752', 'confidence': 1.0}, {'entity': 'papillary dermis', 'concept_id': 'C0682598', 'confidence': 1.0}, {'entity': 'blister', 'concept_id': 'C0005758', 'confidence': 1.0}, {'entity': 'cavity', 'concept_id': 'C0011334', 'confidence': 1.0}], [{'entity': 'inflammatory infiltrate', 'concept_id': 'C3887644', 'confidence': 0.9999999403953552}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'scattered', 'concept_id': 'C0439742', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'thickening', 'concept_id': 'C0205400', 'confidence': 1.0}, {'entity': 'retention', 'concept_id': 'C0035280', 'confidence': 1.0}, {'entity': 'dermal', 'concept_id': 'C0221928', 'confidence': 1.0}, {'entity': 'papillae', 'concept_id': 'C4230196', 'confidence': 0.8667760491371155}], [{'entity': 'lots', 'concept_id': 'C0302148', 'confidence': 0.7982692718505859}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'extravasated', 'concept_id': 'C0015376', 'confidence': 0.868863582611084}, {'entity': 'erythrocytes', 'concept_id': 'C0014772', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'blister', 'concept_id': 'C0005758', 'confidence': 1.0}, {'entity': 'cavity', 'concept_id': 'C0011334', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_592",
"caption_rating": "9"
},
{
"": "1004930",
"caption": "Presence of large fat microcysts with membranous lipodystrophy at the periphery, representing coalescence of remnant cell walls of adipocytes.",
"image_path": "hoV-JkD6Wb0_image_2e6ed1f2-9837-44ad-b695-2071a6947a39.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['large fat microcysts', 'membranous lipodystrophy', 'fibrosis', 'lipophages', 'plasma cells', 'lipophages']",
"noisy_text": " ruptured and fused, and so we've got these large fat microcysts, and if we look at the periphery of the fat microcyst, we've got this lipomembranous change, this kind of arabesque-type fibular material out at the periphery, which basically represents coalescence of remnant cell walls of adipocytes. In addition, within the surrounding tissue, there's a little bit of fibrosis. There are a few lipophages and a very sparse infiltrative lymphocytes, and in this case, a few plasma cells, and of course, these findings are virtually pathognomonic for lipodermatosclerosis, especially in this clinical setting. Personally, in my practice, I see a lot more biopsies",
"corrected_text": " ruptured and fused, and so we've got these large fat microcysts, and if we look at the periphery of the fat microcyst, we've got this lipomembranous change, this kind of arabesque-type fibular material out at the periphery, which basically represents coalescence of remnant cell walls of adipocytes. In addition, within the surrounding tissue, there's a little bit of fibrosis. There are a few lipophages and a very sparse infiltrative lymphocytes, and in this case, a few plasma cells, and of course, these findings are pathognomonic for lipodermatosclerosis, especially in this clinical setting. Personally, in my practice, I see a lot more biopsies",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'fat microcysts', 'concept_id': 'C1513269', 'confidence': 0.871767520904541}, {'entity': 'membranous lipodystrophy', 'concept_id': 'C0406599', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'coalescence', 'concept_id': 'C4727092', 'confidence': 0.8749340176582336}, {'entity': 'remnant', 'concept_id': 'C3272697', 'confidence': 1.0}, {'entity': 'cell walls', 'concept_id': 'C0007623', 'confidence': 1.0}, {'entity': 'adipocytes', 'concept_id': 'C0206131', 'confidence': 1.0}], [{'entity': 'Fibrosis', 'concept_id': 'C0016059', 'confidence': 1.0}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}], [{'entity': 'Pathognomonic findings', 'concept_id': 'C2986472', 'confidence': 0.7794376611709595}, {'entity': 'lipodermatosclerosis', 'concept_id': 'C0406500', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_593",
"caption_rating": "9"
},
{
"": "1008432",
"caption": "The stroma has a myxoid appearance.",
"image_path": "udoW6VSqsm4_image_14476891-beb9-4811-a058-3c775a1b4992.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " Okay, where's the non-epithelial? Like the myxoid type of stroma. Oh, the stroma's got kind of a myxoid. Okay, that's fine. What about the actual neoplastic cells? I thought they are epithelial. Yeah, what kind of differentiation is this? They look like glandular. Yeah, glandular differentiation. So what is your differential when you're dealing with a neoplasm with glandular differentiation? Is this benign or malignant? Honestly, the first thing I thought this could be some sort of weird myxoid tumor. Weird myxoid tumor?",
"corrected_text": " Okay, where's the non-epithelial? Like the myxoid type of stroma. Oh, the stroma's got kind of a myxoid. Okay, that's fine. What about the actual neoplastic cells? I thought they are epithelial. Yeah, what kind of differentiation is this? They look like glandular. Yeah, glandular differentiation. So what is your differential when you're dealing with a neoplasm with glandular differentiation? Is this benign or malignant? Honestly, the first thing I thought this could be some sort of weird myxoid tumor. Weird myxoid tumor?",
"med_umls_ids": "[[{'entity': 'stroma', 'concept_id': 'C0927195', 'confidence': 1.0}, {'entity': 'myxoid', 'concept_id': 'C0205295', 'confidence': 1.0}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}], [{'entity': 'neoplastic cells', 'concept_id': 'C0597032', 'confidence': 1.0}, {'entity': 'glandular differentiation', 'concept_id': 'C1711212', 'confidence': 1.0}], [{'entity': 'differential diagnosis', 'concept_id': 'C0011906', 'confidence': 1.0}, {'entity': 'neoplasm', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'glandular differentiation', 'concept_id': 'C1711212', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_594",
"caption_rating": "8"
},
{
"": "1008592",
"caption": "Eosinophilic gastritis is diagnosed when there are more than five eosinophils per high power field in the stomach.",
"image_path": "r7OA0Trj5hQ_image_e4ca3b4b-74d6-408a-8711-0e8944691e10.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['lamina propria edema', 'muscularis mucosa', 'neutrophils', 'eosinophils', 'stomach', 'esophagus', 'enteritis', 'colitis', 'lamina propria edema', 'muscularis mucosa', 'neutrophils', 'eosinophils', 'stomach', 'esophagus', 'enteritis', 'colitis']",
"noisy_text": " Lamina propria edema and muscularis mucosa coming into the lamina propria. These are the three criterias. When you see it in the anterobiopsy, think of chemical gastritis that can be seen in biliary reflux or NSAID use. Lot of inflammation results. Remember I told you if you see more than five neutrophils, more than five eosinophils sitting in the lamina propria or more than 15 eosinophils per high power field, that is a eosinophilic gastritis, if it is from the stomach. If it is esophagus, it is eosinophilic esophagitis, eosinophilic entritis, eosinophilic colitis. So eosinophilic",
"corrected_text": " Lamina propria edema and muscularis mucosa coming into the lamina propria. These are the three criterias. When you see it in the antral biopsy, think of chemical gastritis that can be seen in biliary reflux or NSAID use. Lot of inflammation results. Remember I told you if you see more than five neutrophils, more than five eosinophils sitting in the lamina propria or more than 15 or more eosinophils per high power field, that is a eosinophilic gastritis, if it is from the stomach. If it is esophagus, it is eosinophilic esophagitis, eosinophilic enteritis, eosinophilic colitis. So eosinophilic",
"med_umls_ids": "[[{'entity': 'Lamina propria edema', 'concept_id': 'C1179187', 'confidence': 0.7593827247619629}, {'entity': 'muscularis mucosa', 'concept_id': 'C0225357', 'confidence': 0.9999998807907104}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'criteria', 'concept_id': 'C0243161', 'confidence': 0.9999998807907104}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}], [{'entity': 'Inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}], [{'entity': 'Eosinophilic gastritis', 'concept_id': 'C0267154', 'confidence': 1.0}, {'entity': 'diagnosed', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}], [{'entity': 'Eosinophilic esophagitis', 'concept_id': 'C0341106', 'confidence': 0.9999999403953552}, {'entity': 'eosinophilic enteritis', 'concept_id': 'C1262481', 'confidence': 1.0}, {'entity': 'eosinophilic colitis', 'concept_id': 'C0267448', 'confidence': 1.0}, {'entity': 'diagnoses', 'concept_id': 'C0011900', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_595",
"caption_rating": "9"
},
{
"": "1005290",
"caption": "Histopathological description of a tumor with interconnected cords and strands, cribriform pattern, loose and edematous vascular stroma, and at least two cell types in the epithelial islands.",
"image_path": "8S4LeiO6Bbk_image_5b62248d-3cea-4103-9edc-5e92e3253386.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['nuclei', 'nuclei']",
"noisy_text": " and the blue staining is generally due to hematoxylin staining the nucleus. So we've got a lot of nuclei here that we'll want to take a look at. Overall, even though this is fragmented, the fact that it's fairly well circumscribed would indicate that it's got more of a benign silhouette. If we move to higher power, we can see that we're dealing with an epithelial rather than a mosaicable tumor. We've got interconnected cords and strands. We have somewhat of a ribiform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of",
"corrected_text": " and the blue staining is generally due to hematoxylin staining the nucleus. So we've got a lot of nuclei here that we'll want to take a look at. Overall, even though this is fragmented, the fact that it's fairly well circumscribed would indicate that it's got more of a benign silhouette. If we move to higher power, we can see that we're dealing with an epithelial rather than a mucinous tumor. We've got interconnected cords and strands. We have somewhat of a cribriform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'cords', 'concept_id': 'C0034869', 'confidence': 0.801885187625885}, {'entity': 'strands', 'concept_id': 'C0600383', 'confidence': 0.800572395324707}, {'entity': 'cribriform pattern', 'concept_id': 'C1333163', 'confidence': 1.0}, {'entity': 'loose', 'concept_id': 'C0205407', 'confidence': 1.0}, {'entity': 'edematous', 'concept_id': 'C0013604', 'confidence': 1.0}, {'entity': 'cell types', 'concept_id': 'C0007634', 'confidence': 1.0}, {'entity': 'epithelial islands', 'concept_id': 'C0221908', 'confidence': 0.675740122795105}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_596",
"caption_rating": "9"
},
{
"": "1004511",
"caption": "Example of atrophy with no defined number of glands due to age and size dependence.",
"image_path": "r7OA0Trj5hQ_image_2310b77e-9111-4a96-98ef-680e62280e5d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['acinar structures resembling pancreas', 'pancreatic acinar-like structures in the GIT', 'acinar structures resembling pancreas', 'pancreatic acinar-like structures in the GIT']",
"noisy_text": " Sometimes the stomach can show acinar structures resembling pancreas. Then it is known as pancreatic acinar metaplasia. This can also happen in the small intestine. There, when you do staining for amylase or trypsin, it will be positive, but on H&E itself, you can see pancreatic acinar-like structures in the GIT. Then it will become pancreatic acinar metaplasia. Here is the best example of atrophy. Again, unfortunately, there is no defined number of glands to be seen because this is age-dependentation, size-dependentation, race-dependent. So",
"corrected_text": " Sometimes the stomach can show acinar structures resembling pancreas. Then it is known as pancreatic acinar metaplasia. This can also happen in the small intestine. There, when you do staining for amylase or trypsin, it will be positive, but on H&E itself, you can see pancreatic acinar-like structures in the GIT. Then it will become pancreatic acinar metaplasia. Here is the best example of atrophy. Again, unfortunately, there is no defined number of glands to be seen because this is age-dependentation, size-dependentation, race-dependent. So",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'pancreatic acinar metaplasia', 'concept_id': 'C4021967', 'confidence': 0.7844848036766052}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'small intestine', 'concept_id': 'C0021852', 'confidence': 1.0}], [{'entity': 'Staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'amylase', 'concept_id': 'C0002712', 'confidence': 1.0}, {'entity': 'trypsin', 'concept_id': 'C0041236', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'intestine', 'concept_id': 'C0021853', 'confidence': 1.0}], [{'entity': 'atrophy', 'concept_id': 'C0333641', 'confidence': 1.0}, {'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'age', 'concept_id': 'C0001779', 'confidence': 1.0}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'dependence', 'concept_id': 'C0011546', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_597",
"caption_rating": "7"
},
{
"": "1004740",
"caption": "The patient had a history of uveitis with characteristic features that were good for sarcoidosis.",
"image_path": "sDFjOtMAYrk_image_2211d8b3-d4db-4cd5-969d-76137a607896.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['uveitis with characteristic features', 'granulomas in sarcoidosis and Crohn\u2019s disease']",
"noisy_text": " patient had sarcoid. So I said, this is probably not IBD, clinicians came down, we want to look at the biopsy, of course. It turns out that they went back and talked to the patient. The patient has a history of uveitis with characteristic features that were good for sarcoidosis. Nobody knew about they treated the patient for sarcoid, re-biopsied the patient. And he was fine. There were no more granulomas on multiple repeat biopsies. And now compare those grannies with the grannies in Crohn's. So here's a giant cell right there, but there was a better one right there. So they're like kind of",
"corrected_text": " patient had sarcoid. So I said, this is probably not IBD, clinicians came down, we want to look at the biopsy, of course. It turns out that they went back and talked to the patient. The patient has a history of uveitis with characteristic features that were good for sarcoidosis. Nobody knew about they treated the patient for sarcoid, re-biopsied the patient. And he was fine. There were no more granulomas on multiple repeat biopsies. And now compare those grannies with the grannies in Crohn's. So here's a giant cell right there, but there was a better one right there. So they're like kind of",
"med_umls_ids": "[[{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'suspected', 'concept_id': 'C0332147', 'confidence': 1.0}, {'entity': 'IBD', 'concept_id': 'C0021390', 'confidence': 1.0}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'history', 'concept_id': 'C0019664', 'confidence': 1.0}, {'entity': 'uveitis', 'concept_id': 'C0042164', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'treated', 'concept_id': 'C1522326', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'biopsies', 'concept_id': 'C0005558', 'confidence': 1.0}, {'entity': 'granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}], [{'entity': 'Comparison', 'concept_id': 'C1707455', 'confidence': 1.0}, {'entity': 'granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'Crohn\u2019s disease', 'concept_id': 'C0010346', 'confidence': 0.8916962146759033}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_598",
"caption_rating": "7"
},
{
"": "1005502",
"caption": "Presence of heavily pigmented melanophages.",
"image_path": "8S4LeiO6Bbk_image_2a656e84-f2e1-48c2-9cf0-1df8b85c49a1.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['cytoplasm', 'dermis']",
"noisy_text": " appearance, a round oval nuclei and a moderate amount of cytoplasm. And then we have nest cords and strands of otherwise banal appearing or banal appearing melanocytes present within the underlying dermis. There is evidence of maturation with depth in these sections, and no mitotic pairs. In the central portion of the specimen, you can see that the dermis is a little more sclerotic. And we've got the presence of separately heavily pigmented melanovagias. And then if we look at our top piece of tissue, again, we have the more banal appearing melanocytes out of the periphery. And centrally, we've got embedded within a sclerotic stroma a second distinct morphologic population of melanocytes. Some of these are dendritic, others have spindled or fusiform-shaped",
"corrected_text": " appearance, a round oval nuclei and a moderate amount of cytoplasm. And then we have nest cords and strands of otherwise banal appearing or banal appearing melanocytes present within the underlying dermis. There is evidence of maturation with depth in these sections, and no mitotic pairs. In the central portion of the specimen, you can see that the dermis is a little more sclerotic. And we've got the presence of separately heavily pigmented melanovagias. And then if we look at our top piece of tissue, again, we have the more banal appearing melanocytes out of the periphery. And centrally, we've got embedded within a sclerotic stroma a second distinct morphologic population of melanocytes. Some of these are dendritic, others have spindle-shaped or fusiform-shaped",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'specimen', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'banal', 'concept_id': 'C0004722', 'confidence': 0.7279530763626099}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}], [{'entity': 'Evidence', 'concept_id': 'C3887511', 'confidence': 1.0}, {'entity': 'maturation', 'concept_id': 'C0678723', 'confidence': 1.0}, {'entity': 'depth', 'concept_id': 'C0205125', 'confidence': 1.0}, {'entity': 'mitotic', 'concept_id': 'C1513354', 'confidence': 1.0}, {'entity': 'pairs', 'concept_id': 'C0600436', 'confidence': 0.8094210028648376}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'heavily', 'concept_id': 'C0337678', 'confidence': 0.6902515292167664}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'melanophages', 'concept_id': 'C3280463', 'confidence': 0.9375340938568115}], [{'entity': 'Sclerotic', 'concept_id': 'C0036429', 'confidence': 0.9999999403953552}, {'entity': 'stroma', 'concept_id': 'C0927195', 'confidence': 1.0}, {'entity': 'morphologic population', 'concept_id': 'C0543482', 'confidence': 0.699425995349884}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_599",
"caption_rating": "8"
},
{
"": "1007237",
"caption": "Small cell carcinoma adjacent to high-grade prostate cancer.",
"image_path": "iklRyY1nBIE_image_85611e49-f237-49c9-b10b-8feb8ef5f243.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['bladder neck', 'prostate', 'biopsy']",
"noisy_text": " And it actually invaded into the bladder. So there was bladder-neck invasion. That was very, very important to document in the report. It's not just good enough to say small cell carcinoma adjacent high-grade prostate cancer. You need to also document the fact that it invades the bladder-neck. That's very, very important for completeness. So on this one, I have just a little biopsy here to show you. So this is a prostate-needle-cored biopsy. That's what this was called, prostate-needle-cored biopsy. And as",
"corrected_text": " And it actually invaded into the bladder. So there was bladder-neck invasion. That was very, very important to document in the report. It's not just good enough to say small cell carcinoma adjacent high-grade prostate cancer. You need to also document the fact that it invades the bladder-neck. That's very, very important for completeness. So on this one, I have just a little biopsy here to show you. So this is a prostate needle biopsy-cored biopsy. That's what this was called, prostate needle biopsy-cored biopsy. And as",
"med_umls_ids": "[[{'entity': 'Small cell carcinoma', 'concept_id': 'C0149925', 'confidence': 1.0}, {'entity': 'adjacent', 'concept_id': 'C0205117', 'confidence': 1.0}, {'entity': 'high-grade', 'concept_id': 'C1512433', 'confidence': 0.9347730875015259}], [{'entity': 'Bladder', 'concept_id': 'C0005682', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_600",
"caption_rating": "8"
},
{
"": "1005620",
"caption": "Clodin-1 is often expressed in perineuriomas, which can be a pitfall in diagnosis as it may resemble low-grade fibromyxoid sarcoma. Glut-1 is usually negative in perineuriomas but may be positive in rare cases of low-grade fibromyxoid sarcoma. MUC4 is a sensitive and specific marker for low-grade fibromyxoid sarcoma and should be negative in perineuriomas and DFSP.",
"image_path": "QDb68_G1HR4_image_f1e52b92-f100-4694-8fb9-5f626b589ad4.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The one stain that was described a few years ago as being helpful here is called MUC4, M-U-C-4. MUC4 is in the setting of a fibroblastic spindle cell tumor like this, it is a very sensitive and specific marker at least as of today's date in 2018, so far it tends to be very sensitive and specific marker for low-grade fibromyxoid sarcoma and it should be negative in perineuriomas and DFSP and other entities in the differential diagnosis. Now I'm",
"corrected_text": " They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The one stain that was described a few years ago as being helpful here is called MUC4, M-U-C-4. MUC4 is in the setting of a fibroblastic spindle cell tumor like this, it is a very sensitive and specific marker at least as of today's date in 2018, so far it tends to be very sensitive and specific marker for low-grade fibromyxoid sarcoma and it should be negative in perineuriomas and DFSP and other entities in the differential diagnosis. Now I'm",
"med_umls_ids": "[[{'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}, {'entity': 'expressed', 'concept_id': 'C0017262', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'rare', 'concept_id': 'C0521114', 'confidence': 1.0}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'MUC4', 'concept_id': 'C1417496', 'confidence': 0.9999999403953552}, {'entity': 'sensitive', 'concept_id': 'C0020517', 'confidence': 1.0}, {'entity': 'marker', 'concept_id': 'C0005516', 'confidence': 0.9999999403953552}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_601",
"caption_rating": "9"
},
{
"": "1008701",
"caption": "The fibrovascular core contains well-defined nerve fascicles with spindle-shaped cells that are positive for S100 and SOX10, indicating a neural tumor.",
"image_path": "8S4LeiO6Bbk_image_d73237ea-0389-4d09-a0bf-a7cf76772156.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['dome-shaped papule', 'acral site', 'thick stratum corneum', 'absence of hair follicles', 'fibrovascular core', 'nerve fascicles', 'spindle-shaped cells', 'S100', 'SOX10', 'rudimentary supernumerary digit', 'dome-shaped papule', 'acral site', 'thick stratum corneum', 'absence of hair follicles', 'fibrovascular core', 'nerve fascicles', 'spindle-shaped cells', 'S100', 'SOX10', 'rudimentary supernumerary digit']",
"noisy_text": " we've got a dome-shaped papule and that the biopsy is from an acral site. Notice that we've got a very very thick stratum corneum and a marked to virtual absence of hair follicles within the specimen. We do have kind of this fibrovascular core and of course in the center of the fibrovascular core here we've got several well-defined nerve fascicles and the spindled cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions",
"corrected_text": " we've got a dome-shaped papule and that the biopsy is from an acral site. Notice that we've got a very very thick stratum corneum and a marked to virtual absence of hair follicles within the specimen. We do have kind of this fibrovascular core and of course in the center of the fibrovascular core here we've got several well-defined nerve fascicles and the spindle cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions",
"med_umls_ids": "[[{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'acral site', 'concept_id': 'C0439746', 'confidence': 0.717435359954834}, {'entity': 'dome-shaped papule', 'concept_id': 'C1711316', 'confidence': 0.752353847026825}], [{'entity': 'specimen', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'stratum corneum', 'concept_id': 'C0221921', 'confidence': 1.0}, {'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'hair follicles', 'concept_id': 'C0221971', 'confidence': 0.9999998807907104}], [{'entity': 'fibrovascular', 'concept_id': 'C0392759', 'confidence': 1.0}, {'entity': 'nerve fascicles', 'concept_id': 'C1185741', 'confidence': 0.8332967758178711}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'S100', 'concept_id': 'C3273837', 'confidence': 1.0}, {'entity': 'SOX10', 'concept_id': 'C1420317', 'confidence': 0.9999998807907104}, {'entity': 'neural tumor', 'concept_id': 'C1334956', 'confidence': 1.0}], [{'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'rudimentary supernumerary digit', 'concept_id': 'C0152427', 'confidence': 0.8142021894454956}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_602",
"caption_rating": "10"
},
{
"": "1006426",
"caption": "No internal elastic lamina seen in the image.",
"image_path": "r7OA0Trj5hQ_image_997a8219-edca-40e9-b1e8-2aa60d52f990.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Severe dysplasia', 'Thick and thin blood vessels', 'Thick vessel wall', 'Narrowing of lumen', 'Vein and artery identification', 'No internal elastic lamina', 'Vein and artery identification', 'Severe dysplasia', 'Thick and thin blood vessels', 'Thick vessel wall', 'Narrowing of lumen', 'Vein and artery identification', 'No internal elastic lamina']",
"noisy_text": " And in the resection, you see like a heavy malformation, isn't it? Thick and thin blood vessels of varying sizes are seen. In high power, you can see very thick vessel wall with the narrowing of the lumen, whereas here, it is relatively preserved. So you want to know whether it is a vein or artery. Please believe me, this is a vein, and this is an artery. And that is proved by the elastic tissue strain. These are all pictures from Dr. Gonzalez's Twitter. And you can see here, there is no internal elastic lamina, whereas here,",
"corrected_text": " And in the resection, you see like a heavy malformation, isn't it? Thick and thin blood vessels of varying sizes are seen. In high power, you can see very thick vessel wall with the narrowing of the lumen, whereas here, it is relatively preserved. So you want to know whether it is a vein or artery. Please believe me, this is a vein, and this is an artery. And that is proved by the elastic tissue strain. These are all pictures from Dr. Gonzalez's Twitter. And you can see here, there is no internal elastic lamina, whereas here,",
"med_umls_ids": "[[{'entity': 'Severe', 'concept_id': 'C0205082', 'confidence': 1.0}, {'entity': 'resection', 'concept_id': 'C0015252', 'confidence': 1.0}], [{'entity': 'Thick', 'concept_id': 'C1280412', 'confidence': 1.0}, {'entity': 'thin', 'concept_id': 'C0205168', 'confidence': 1.0}, {'entity': 'sizes', 'concept_id': 'C0456389', 'confidence': 1.0}], [{'entity': 'Thick vessel wall', 'concept_id': 'C1180033', 'confidence': 0.6420797109603882}, {'entity': 'narrowing', 'concept_id': 'C0332463', 'confidence': 1.0}, {'entity': 'lumen', 'concept_id': 'C0524461', 'confidence': 0.9999998807907104}, {'entity': 'power', 'concept_id': 'C0032863', 'confidence': 1.0}], [{'entity': 'Identification', 'concept_id': 'C0020792', 'confidence': 1.0}, {'entity': 'vein', 'concept_id': 'C0042449', 'confidence': 1.0}, {'entity': 'artery', 'concept_id': 'C0003842', 'confidence': 1.0}, {'entity': 'elastic tissue', 'concept_id': 'C0013762', 'confidence': 1.0}, {'entity': 'strain', 'concept_id': 'C0080194', 'confidence': 1.0}], [{'entity': 'image', 'concept_id': 'C1696103', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_603",
"caption_rating": "8"
},
{
"": "1008720",
"caption": "Papillary projections protrude into the lumina.",
"image_path": "8S4LeiO6Bbk_image_7a1fbb54-1a16-4c4d-ba48-7199d6c67247.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['siderophages']",
"noisy_text": " by these dilated vascular channels. Let's look at the bottom piece, which frequently do contain these papillary projections, which protrude into the lumina, these plump endothelial cells, and then at the periphery, more compressed vascular channels, which dissect between collagen bundles. And it's at the periphery one frequently sees extravasated erythrocytes, siderophages, and an infiltrate of lymphocytes. So targetoid hemocidiotic hemangioma. Sometimes it can be quite difficult to distinguish these from patch gage stage Kaposi's. And again, HHV8 stain will help you because these are routinely negative for HHVA and the Kaposi's, of course, will always stain with an HHV8 stain. And we will close out our discussion with slide number 12, which is kind of a cool case to end on. And we have two pieces of tissue here. And if",
"corrected_text": " by these dilated vascular channels. Let's look at the bottom piece, which frequently do contain these papillary projections, which protrude into the lumina, these plump endothelial cells, and then at the periphery, more compressed vascular channels, which dissect between collagen bundles. And it's at the periphery one frequently sees extravasated erythrocytes, siderophages, and an infiltrate of lymphocytes. So targetoid hemosiderotic hemangioma. Sometimes it can be quite difficult to distinguish these from patch gage stage Kaposi's. And again, HHV8 stain will help you because these are routinely negative for HHVA and the Kaposi's, of course, will always stain with an HHV8 stain. And we will close out our discussion with slide number 12, which is kind of a cool case to end on. And we have two pieces of tissue here. And if",
"med_umls_ids": "[[{'entity': 'Dilated', 'concept_id': 'C0700124', 'confidence': 0.9999999403953552}, {'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}], [{'entity': 'Papillary projections', 'concept_id': 'C0016538', 'confidence': 0.7451471090316772}, {'entity': 'lumina', 'concept_id': 'C0524462', 'confidence': 0.845600426197052}], [{'entity': 'Enlarged endothelial cells', 'concept_id': 'C0423263', 'confidence': 0.7785332202911377}], [{'entity': 'Compressed vascular channels', 'concept_id': 'C1336948', 'confidence': 0.5993747711181641}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'bundles', 'concept_id': 'C3658308', 'confidence': 0.8706014752388}], [{'entity': 'Extravasated', 'concept_id': 'C0015376', 'confidence': 0.868863582611084}, {'entity': 'erythrocytes', 'concept_id': 'C0014772', 'confidence': 1.0}, {'entity': 'siderophages', 'concept_id': 'C1136253', 'confidence': 0.7251443266868591}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}], [{'entity': 'Targetoid hemosiderotic hemangioma', 'concept_id': 'C0346076', 'confidence': 0.9999999403953552}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'targetoid hemosiderotic hemangioma', 'concept_id': 'C0346076', 'confidence': 0.9999999403953552}, {'entity': \"patch stage Kaposi's\", 'concept_id': 'C0280201', 'confidence': 0.7629613280296326}], [{'entity': 'HHV8', 'concept_id': 'C0036220', 'confidence': 1.0}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_604",
"caption_rating": "8"
},
{
"": "1008346",
"caption": "Loss of cellular polarity is observed in the stratified region.",
"image_path": "r7OA0Trj5hQ_image_bee456fa-6f54-4e64-9f71-42d805a33b94.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Loss of cellular polarity in the stratified region', 'Cribriform pattern', 'Intraluminal proliferation of the epithelium within a single gland.', 'Intraluminal proliferation of the epithelium within a single gland.']",
"noisy_text": " So there is loss of polarity. Okay, so here also it is stratified, reaching up to the top, and it is showing loss of polarity. And see the cribriformic. And this is a micropapillary process. Since it's a high power, you are not able to appreciate it better. I will show it to you in the other pictures. But here you can see cribriformic. What happens in cribriformic? It is not crowded back to back glands. It is epithelial growth within your gland. This itself is a single gland. Within that gland, this epithelium is growing and connecting the other side of the lumen. So the intra-glandular proliferation of the epithelium is very,",
"corrected_text": " So there is loss of polarity. Okay, so here also it is stratified, reaching up to the top, and it is showing loss of polarity. And see the cribriform. And this is a micropapillary process. Since it's a high power, you are not able to appreciate it better. I will show it to you in the other pictures. But here you can see cribriform. What happens in cribriform? It is not crowded back to back glands. It is epithelial growth within your gland. This itself is a single gland. Within that gland, this epithelium is growing and connecting the other side of the lumen. So the intraluminal proliferation of the epithelium is very,",
"med_umls_ids": "[[{'entity': 'Loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'cellular polarity', 'concept_id': 'C0085304', 'confidence': 1.0}, {'entity': 'stratified region', 'concept_id': 'C0205363', 'confidence': 0.800367534160614}], [{'entity': 'Cribriform pattern', 'concept_id': 'C1333163', 'confidence': 1.0}], [{'entity': 'Epithelial growth', 'concept_id': 'C1271404', 'confidence': 0.8868558406829834}, {'entity': 'single gland', 'concept_id': 'C0037179', 'confidence': 0.775238573551178}, {'entity': 'lumen', 'concept_id': 'C0524461', 'confidence': 0.9999998807907104}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_605",
"caption_rating": "8"
},
{
"": "1006402",
"caption": "Muscle fibers are seen running into the lamina propria.",
"image_path": "r7OA0Trj5hQ_image_dea08b06-85dd-4419-b590-b677fadd042a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['muscle fibers', 'intestinal metaplasia', 'lamina propria']",
"noisy_text": " where, again, you can see the muscle fibers running into the lamina propria. If you are in doubt, you can use the trichrome strain, where you can identify the muscle running up there. And you can see nice intestinal metaplasia there. Again, the number of glands are less in here. So this is chronic atrophic gastritis with intestinal metaplasia with muscularization of the lamina propria. More than one pathology involved in this biopsy. Plastic changes seen above are known as TIS. Once they cross the muscular ischemicosa, then only they are eligible for T1. So muscular ischemicosa acts like",
"corrected_text": " where, again, you can see the muscle fibers running into the lamina propria. If you are in doubt, you can use the trichrome strain, where you can identify the muscle running up there. And you can see nice intestinal metaplasia there. Again, the number of glands are less in here. So this is chronic atrophic gastritis with intestinal metaplasia with muscularization of the lamina propria. More than one pathology involved in this biopsy. Plastic changes seen above are known as TIS. Once they cross the muscularis propria, then only they are eligible for T1. So muscularis propria acts like",
"med_umls_ids": "[[{'entity': 'Muscle fibers', 'concept_id': 'C0242697', 'confidence': 1.0}, {'entity': 'running', 'concept_id': 'C0035953', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}], [{'entity': 'Intestinal metaplasia', 'concept_id': 'C0334037', 'confidence': 1.0}], [{'entity': 'Chronic atrophic gastritis', 'concept_id': 'C0017154', 'confidence': 1.0}, {'entity': 'intestinal metaplasia', 'concept_id': 'C0334037', 'confidence': 1.0}, {'entity': 'muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'Plastic changes', 'concept_id': 'C0392747', 'confidence': 0.7598782777786255}, {'entity': 'TIS', 'concept_id': 'C0475413', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_606",
"caption_rating": "7"
},
{
"": "1005697",
"caption": "Increased cellularity may be present in some cases, but pre-treatment with radiation can cause changes in the tissue that make it difficult to diagnose. Treatment options may not differ significantly based on the diagnosis.",
"image_path": "pBR26SS0FX8_image_c2fccb8d-1a3a-4449-b4c9-281b35a4eccf.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Hematopathology', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " And I've had occasional times on a needle where I said, there's a little increased cellularity. I don't know if it's enough to be round cell or not. The problem is if they pre-treat with radiation, a lot of the stuff melts away, including the round cell. So the excision specimen, there's no way to really know. It's not like there's any real major difference though. It's not like we have some special therapy to offer. The treatment's gonna be probably the same. Although I've seen times where they decided to only",
"corrected_text": " And I've had occasional times on a needle where I said, there's a little increased cellularity. I don't know if it's enough to be round cell or not. The problem is if they pre-treat with radiation, a lot of the stuff melts away, including the round cell. So the excision specimen, there's no way to really know. It's not like there's any real major difference though. It's not like we have some special therapy to offer. The treatment's gonna be probably the same. Although I've seen times where they decided to only",
"med_umls_ids": "[[{'entity': 'Increased', 'concept_id': 'C0205217', 'confidence': 1.0}, {'entity': 'cellularity', 'concept_id': 'C0178539', 'confidence': 0.9999999403953552}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'pre-treatment', 'concept_id': 'C0419819', 'confidence': 0.7933163046836853}, {'entity': 'radiation', 'concept_id': 'C0034519', 'confidence': 1.0}, {'entity': 'changes', 'concept_id': 'C0392747', 'confidence': 1.0}, {'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'Treatment options', 'concept_id': 'C0683525', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_607",
"caption_rating": "8"
},
{
"": "1008476",
"caption": "The tumor can be confused with neurofibromas and desmoid fibromatosis.",
"image_path": "QDb68_G1HR4_image_c646b41c-ab96-4a62-9308-500ccefd6ffd.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['spindle cell thing', 'neurofibromas', 'pinkish bland appearance', 'pink fibrous background', 'fibroblastic looking', 'spindle cell thing', 'neurofibromas', 'pinkish bland appearance', 'pink fibrous background', 'fibroblastic looking']",
"noisy_text": " misdiagnosed originally as either fibroma which is a good example of why it's dangerous to call something just fibroma not otherwise specified just because you see a spindle cell thing that looks fibroblastic and benign and you don't have a good name for it. That doesn't mean it's a fibroma, that's the way that tumors like this get missed. And the other thing is that these can get confused for neurofibromas so that pinkish bland appearance and the pink fibrous background can easily get confused with other things. Also desmoid fibromatosis, I've got a video about that, I'll put a link down in the video description below, you can watch that if you're curious about desmoid tumors. Those are all fibrous fibroblastic tumors that are tumors with a fibroblastic looking background that",
"corrected_text": " misdiagnosed originally as either fibroma which is a good example of why it's dangerous to call something just fibroma not otherwise specified just because you see a spindle cell thing that looks fibroblastic and benign and you don't have a good name for it. That doesn't mean it's a fibroma, that's the way that tumors like this get missed. And the other thing is that these can get confused for neurofibromas so that pinkish bland appearance and the pink fibrous background can easily get confused with other things. Also desmoid fibromatosis, I've got a video about that, I'll put a link down in the video description below, you can watch that if you're curious about desmoid tumors. Those are all fibrous fibroblastic tumors that are tumors with a fibroblastic looking background that",
"med_umls_ids": "[[{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'misdiagnosed', 'concept_id': 'C0679838', 'confidence': 0.896425724029541}, {'entity': 'fibroma', 'concept_id': 'C0016045', 'confidence': 1.0}, {'entity': 'danger', 'concept_id': 'C1428845', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'neurofibromas', 'concept_id': 'C0027830', 'confidence': 1.0}, {'entity': 'desmoid', 'concept_id': 'C0079218', 'confidence': 1.0}, {'entity': 'fibromatosis', 'concept_id': 'C0016048', 'confidence': 1.0}], [{'entity': 'Desmoid fibromatosis', 'concept_id': 'C0079218', 'confidence': 1.0}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_608",
"caption_rating": "7"
},
{
"": "1004856",
"caption": "Ectatic vessels are present in the papillary dermis with pallor consistent with edema and perivascular infiltrate of lymphocytes.",
"image_path": "hoV-JkD6Wb0_image_12fbbe53-4b6b-44c3-b6aa-ff4f21a71e8b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['ectatic vessels', 'papillary dermis', 'perivascular infiltrate of lymphocytes', 'collections of immune cells', 'narrow cuff of mononuclear cells']",
"noisy_text": " and we'll take a look at two of them, you had to review similar findings, bisected punch. And as expected, there are ectatic vessels here. Let me tilt the slide here. And the papillary dermis, a little bit of pallor consistent with edema, a little bit of a perivascular infiltrate of lymphocytes. And then present throughout the dermis, there are a few collections of epithelioid histiocytes. Here, there's one right there. And down here, we have another collection of epithelioid histiocytes. These are surrounded by a narrow cuff of mononuclear cells, but many",
"corrected_text": " and we'll take a look at two of them, you had to review similar findings, bisected punch. And as expected, there are ectatic vessels here. Let me tilt the slide here. And the papillary dermis, a little bit of pallor consistent with edema, a little bit of a perivascular infiltrate of lymphocytes. And then present throughout the dermis, there are a few collections of epithelioid histiocytes. Here, there's one right there. And down here, we have another collection of epithelioid histiocytes. These are surrounded by a narrow cuff of mononuclear cells, but many",
"med_umls_ids": "[[{'entity': 'Ectatic vessels', 'concept_id': 'C0005847', 'confidence': 0.7720959186553955}, {'entity': 'papillary dermis', 'concept_id': 'C0682598', 'confidence': 1.0}, {'entity': 'pallor', 'concept_id': 'C0030232', 'confidence': 1.0}, {'entity': 'consistent with', 'concept_id': 'C0332290', 'confidence': 1.0}, {'entity': 'edema', 'concept_id': 'C0013604', 'confidence': 0.9999999403953552}, {'entity': 'perivascular', 'concept_id': 'C0442165', 'confidence': 1.0}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}], [{'entity': 'Collections', 'concept_id': 'C0600644', 'confidence': 0.8663196563720703}, {'entity': 'immune cells', 'concept_id': 'C4330475', 'confidence': 0.8268961906433105}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'surrounded', 'concept_id': 'C1282914', 'confidence': 1.0}, {'entity': 'cuff', 'concept_id': 'C0441107', 'confidence': 1.0}, {'entity': 'mononuclear cells', 'concept_id': 'C0806987', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_609",
"caption_rating": "9"
},
{
"": "1004303",
"caption": "Description of translocation sarcoma in myxoid liposarcoma, with FUS-DDIT3 being the most common translocation.",
"image_path": "pBR26SS0FX8_image_a77819b1-4779-43cd-b68e-86b89b08d3fd.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Hematopathology', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " in regular conventional myxoid liposarcoma. You see these little cells, they are also very bland. Again, a translocation sarcoma, right? So these cells have a translocation. FUSDDIT3 used to be called FUSCHOP, was the most common one. Occasionally a subset of them like 5% or so will have EWSR1, Ewing's gene rearranged with DDIT3. And so if you haven't learned yet that a lot of times if there's a rearrangement of EWSR1 with some other gene, eventually someone's gonna find cases that have FUS rearranged with that same gene and vice versa because FUS and EWSR1 are similar genes, a kind of same gene family, which again, this is way over my head, I'm not a molecular pathologist. But the point is they often swap out for one another. So that's",
"corrected_text": " in regular conventional myxoid liposarcoma. You see these little cells, they are also very bland. Again, a translocation sarcoma, right? So these cells have a translocation. FUS-DDIT3 used to be called FUSCHOP, was the most common one. Occasionally a subset of them like 5% or so will have EWSR1, Ewing's gene rearranged with DDIT3. And so if you haven't learned yet that a lot of times if there's a rearrangement of EWSR1 with some other gene, eventually someone's gonna find cases that have FUS rearranged with that same gene and vice versa because FUS and EWSR1 are similar genes, a kind of same gene family, which again, this is way over my head, I'm not a molecular pathologist. But the point is they often swap out for one another. So that's",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'translocation sarcoma', 'concept_id': 'C0040715', 'confidence': 0.7855618000030518}, {'entity': 'myxoid liposarcoma', 'concept_id': 'C0206634', 'confidence': 1.0}, {'entity': 'FUS-DDIT3', 'concept_id': 'C1852061', 'confidence': 0.894819438457489}, {'entity': 'translocation', 'concept_id': 'C0040715', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_610",
"caption_rating": "8"
},
{
"": "1006540",
"caption": "Pronounced basal cell change along the DEJ.",
"image_path": "8S4LeiO6Bbk_image_24e7ef9f-fdec-4317-a973-ebbc11a14881.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['superficial perivascular infiltrate', 'epidermis', 'basement of the rete ridge pattern', 'basal cell change along the DEJ', 'dyskeratotic cells within the basal layer', 'papillary dermis']",
"noisy_text": " Moving on to slide number eight. Slide number eight is the first of two interface dermatitis that we're going to be looking at. This is a bisected punch biopsy from the trunk or proximal extremity. Get that down and in this specimen we can see that we've got a superficial perivascular infiltrate present within the dermis. We've clearly got evidence of some epidural change here. The epidermis is quite thin, the basement of the Reedy ridge pattern. We have a basket we've cornified layer but as we zoom in we can see that we've got pronounced bacular change along the DEJ, scattered dyskeratotic cells within the basal layer, and within the papillary dermis we have a",
"corrected_text": " Moving on to slide number eight. Slide number eight is the first of two interface dermatitis that we're going to be looking at. This is a bisected punch biopsy from the trunk or proximal extremity. Get that down and in this specimen we can see that we've got a superficial perivascular infiltrate present within the dermis. We've clearly got evidence of some epidural change here. The epidermis is quite thin, the basement of the rete ridge pattern. We have a basket we've cornified layer but as we zoom in we can see that we've got pronounced basal cell change along the DEJ, scattered dyskeratotic cells within the basal layer, and within the papillary dermis we have a",
"med_umls_ids": "[[{'entity': 'punch biopsy', 'concept_id': 'C0182557', 'confidence': 1.0}, {'entity': 'trunk', 'concept_id': 'C0225442', 'confidence': 0.9999999403953552}, {'entity': 'proximal extremity', 'concept_id': 'C0015385', 'confidence': 0.745482325553894}], [{'entity': 'Superficial', 'concept_id': 'C0205124', 'confidence': 1.0}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}], [{'entity': 'Evidence', 'concept_id': 'C3887511', 'confidence': 1.0}, {'entity': 'epidural change', 'concept_id': 'C0228134', 'confidence': 0.7621071338653564}], [{'entity': 'Thin epidermis', 'concept_id': 'C4231265', 'confidence': 1.0}, {'entity': 'basement', 'concept_id': 'C0085872', 'confidence': 0.772655725479126}, {'entity': 'rete', 'concept_id': 'C0010306', 'confidence': 0.7033917903900146}, {'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}], [{'entity': 'basal cell', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'DEJ', 'concept_id': 'C0385794', 'confidence': 0.5962325930595398}], [{'entity': 'Scattered', 'concept_id': 'C0439742', 'confidence': 1.0}, {'entity': 'dyskeratotic cells', 'concept_id': 'C1512098', 'confidence': 0.8970272541046143}, {'entity': 'basal layer', 'concept_id': 'C0221925', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_611",
"caption_rating": "8"
},
{
"": "1004985",
"caption": "Metastasis can recur or metastasize long after diagnosis, often to the lung or pleura.",
"image_path": "QDb68_G1HR4_image_b3c3132f-0ea6-4040-a517-87c50dadd4c7.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " diagnosis when a metastasis finally shows up. So unfortunately, that's a frustrating thing I think for both the treating physicians and the patients to know that basically you're never totally in the clear these things can recur or metastasize very, very long after diagnosis. When they metastasize, they often go to the lung or the pleura and there probably is some benefit at least in the opinion of some of the people that I know who treat these sarcomas in removing solitary metastases from the lung if they're surgically amenable to surgical resection that you can remove the metastasis and then the patient may go quite a few more years before having another metastasis. So you can really kind of prolong the disease course by removing metastasis. Obviously if you're a patient watching this that has this tumor, please make sure you see an expert",
"corrected_text": " diagnosis when a metastasis finally shows up. So unfortunately, that's a frustrating thing I think for both the treating physicians and the patients to know that basically you're never totally in the clear these things can recur or metastasize very, very long after diagnosis. When they metastasize, they often go to the lung or the pleura and there probably is some benefit at least in the opinion of some of the people that I know who treat these sarcomas in removing solitary metastases from the lung if they're surgically amenable to surgical resection that you can remove the metastasis and then the patient may go quite a few more years before having another metastasis. So you can really kind of prolong the disease course by removing metastasis. Obviously if you're a patient watching this that has this tumor, please make sure you see an expert",
"med_umls_ids": "[[{'entity': 'Metastasis', 'concept_id': 'C0027627', 'confidence': 1.0}, {'entity': 'metastasize', 'concept_id': 'C0027627', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'lung', 'concept_id': 'C0024109', 'confidence': 1.0}, {'entity': 'pleura', 'concept_id': 'C0032225', 'confidence': 1.0}], [{'entity': 'Surgical resection', 'concept_id': 'C0015252', 'confidence': 1.0}, {'entity': 'solitary metastases', 'concept_id': 'C0027627', 'confidence': 0.7712292075157166}, {'entity': 'lung', 'concept_id': 'C0024109', 'confidence': 1.0}, {'entity': 'disease course', 'concept_id': 'C0242656', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_612",
"caption_rating": "7"
},
{
"": "1007698",
"caption": "Too many melanocytes in the matrix are highly suspicious for melanoma in situ.",
"image_path": "8S4LeiO6Bbk_image_96db8195-9fd3-493b-af2d-cae6a387df27.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Presence of several melanocytes', 'too many melanocytes']",
"noisy_text": " examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matricle epithelium in the matricle layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that being said, we'll go ahead and move on to slide number two, which was a melanin A or Mk1 immunohistochemical stain of this same piece of tissue. Underneath this bubble here we have our control. This is",
"corrected_text": " examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matrix epithelium in the matrix layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that being said, we'll go ahead and move on to slide number two, which was a melanin A or Mk1 immunohistochemical stain of this same piece of tissue. Underneath this bubble here we have our control. This is",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'nests', 'concept_id': 'C0035253', 'confidence': 0.7275967001914978}, {'entity': 'confluence', 'concept_id': 'C0226863', 'confidence': 0.857487678527832}, {'entity': 'solitary units', 'concept_id': 'C0205171', 'confidence': 0.7227572798728943}, {'entity': 'base', 'concept_id': 'C0002055', 'confidence': 1.0}, {'entity': 'matrix epithelium', 'concept_id': 'C0014609', 'confidence': 0.7584323883056641}, {'entity': 'matrix layer', 'concept_id': 'C0331858', 'confidence': 0.71736741065979}, {'entity': 'basal layer', 'concept_id': 'C0221925', 'confidence': 1.0}, {'entity': 'matrix', 'concept_id': 'C0331858', 'confidence': 1.0}, {'entity': 'upper portions', 'concept_id': 'C0449719', 'confidence': 0.6251541972160339}, {'entity': 'matrix', 'concept_id': 'C0331858', 'confidence': 1.0}, {'entity': 'pagetoid', 'concept_id': 'C1518847', 'confidence': 0.8801172375679016}, {'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}], [{'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'matrix', 'concept_id': 'C0331858', 'confidence': 1.0}, {'entity': 'suspicious', 'concept_id': 'C0750493', 'confidence': 1.0}, {'entity': 'melanoma', 'concept_id': 'C0025202', 'confidence': 1.0}, {'entity': 'in situ', 'concept_id': 'C0444498', 'confidence': 0.9999999403953552}]]",
"magnification": "1.0",
"height": "758.0",
"width": "1920.0",
"id": "test_613",
"caption_rating": "8"
},
{
"": "1004878",
"caption": "High-grade prostatic adenocarcinoma was found to be intimately associated with small cell carcinoma in this case.",
"image_path": "iklRyY1nBIE_image_f478f409-67bd-40fc-b80f-d5ca0105e9d1.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['High-grade prostatic adenocarcinoma intimately associated with small cell carcinoma.']",
"noisy_text": " sometimes you get bladder neck tissue in the same sample. And when we have a discussion tomorrow about the bladder cases, the same thing happens in the bladder. You can get a so-called TUR-BT sample that has prostate tissue present. In the prostate, you can have a TUR-P sample that has bladder neck tissue present. And in this particular case, as I said, we were fortunate enough to have high-grade conventional prostate cancer intimately associated with this small cell carcinoma. So it's most likely the differentiation of that. But there are some cases in which there is no well-differentiated or conventional cancer anywhere. All you see is small cell. And then the clinicians may ask, where is this coming from? Is this coming from the prostate? Is this coming from the bladder? And sometimes it's a challenge. Some of us would say it's probably an academic question because they're going to be treated the same way. But sometimes our clinical colleagues want to know. Because things like androgen deprivation therapy are off the table if it's coming from the prostate. And there are different ways one can figure that out. If you're fortunate enough to have egg expression, because studies have shown this, if you're fortunate enough",
"corrected_text": " sometimes you get bladder neck tissue in the same sample. And when we have a discussion tomorrow about the bladder cases, the same thing happens in the bladder. You can get a so-called TUR-BT sample that has prostate tissue present. In the prostate, you can have a TUR-P sample that has bladder neck tissue present. And in this particular case, as I said, we were fortunate enough to have high-grade conventional prostate cancer intimately associated with this small cell carcinoma. So it's most likely the differentiation of that. But there are some cases in which there is no well-differentiated or conventional cancer anywhere. All you see is small cell. And then the clinicians may ask, where is this coming from? Is this coming from the prostate? Is this coming from the bladder? And sometimes it's a challenge. Some of us would say it's probably an academic question because they're going to be treated the same way. But sometimes our clinical colleagues want to know. Because things like androgen deprivation therapy are off the table if it's coming from the prostate. And there are different ways one can figure that out. If you're fortunate enough to have egg expression, because studies have shown this, if you're fortunate enough",
"med_umls_ids": "[[{'entity': 'Bladder', 'concept_id': 'C0005682', 'confidence': 1.0}, {'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'prostate tissue', 'concept_id': 'C1514521', 'confidence': 0.8824390769004822}, {'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}], [{'entity': 'High-grade prostatic adenocarcinoma', 'concept_id': 'C3642254', 'confidence': 0.7883367538452148}, {'entity': 'associated with', 'concept_id': 'C0332281', 'confidence': 1.0}, {'entity': 'small cell carcinoma', 'concept_id': 'C0149925', 'confidence': 1.0}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}], [{'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'conventional', 'concept_id': 'C0439858', 'confidence': 1.0}, {'entity': 'cancer', 'concept_id': 'C0006826', 'confidence': 0.9999998807907104}, {'entity': 'present', 'concept_id': 'C0150312', 'confidence': 0.9999998807907104}, {'entity': 'small cell carcinoma', 'concept_id': 'C0149925', 'confidence': 1.0}], [{'entity': 'Differentiating', 'concept_id': 'C0205615', 'confidence': 1.0}, {'entity': 'origin', 'concept_id': 'C0079946', 'confidence': 1.0}, {'entity': 'small cell carcinoma', 'concept_id': 'C0149925', 'confidence': 1.0}, {'entity': 'treatment', 'concept_id': 'C0039798', 'confidence': 1.0}, {'entity': 'decisions', 'concept_id': 'C0679006', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_614",
"caption_rating": "9"
},
{
"": "1007633",
"caption": "Contains at least two distinct clonal populations of melanocytes with different morphology.",
"image_path": "8S4LeiO6Bbk_image_359fb1b6-fa83-4703-974b-2bbcc5a627f0.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Dendritic and spindle-shaped melanocytes', 'Heavily pigmented melanophages', 'Sclerotic stroma', 'Combined melanocytic nevus with features of common/benign nevus and blue nevus', 'Dendritic and spindle-shaped melanocytes']",
"noisy_text": " or fusiform-shaped nuclei. They're arranged in short, intersecting vascals. And in between the dendritic and spindled melanocytes, we have very heavily pigmented melanovagias, all set in a sclerotic stroma. So basically, we have here a combined melanocytic nevus, one that has features of both a common or banal nevus and a blue nevus. And this is amongst the most common type of combined melanocytic nevus. By definition, a combined melanocytic nevus has at least two, sometimes more, distinct clonal populations of melanocytes that have a different morphology. And sometimes this is referred to as a true blue nevus because it's a true nevus or a banal nevus and a blue nevus. But it's possible to have all kinds of combinations. We can get a blue nevus with a spitz nevus. We can get balloon cell nevi. Those are combined nevi because you usually have a population of banal appearing melanocytes and balloon melanocytes. At that point, inactivated melanocytic tumors are frequently combined nevi, commonly characterized by banal nevus and a population of very epithelial spits like melanocytes. So anyway, all possible combinations are... And in actuality, a deep penetrating nevus is frequently combined nevus with a combination of banal nevus and what looks oftentimes like a cellular blue nevus. So anyway, this is a combined melanocytic nevus.",
"corrected_text": " or fusiform-shaped nuclei. They're arranged in short, intersecting vessels. And in between the dendritic and spindled melanocytes, we have very heavily pigmented melanophages, all set in a sclerotic stroma. So basically, we have here a combined melanocytic nevus, one that has features of both a common or banal nevus and a blue nevus. And this is amongst the most common type of combined melanocytic nevus. By definition, a combined melanocytic nevus has at least two, sometimes more, distinct clonal populations of melanocytes that have a different morphology. And sometimes this is referred to as a true blue nevus because it's a true nevus or a banal nevus and a blue nevus. But it's possible to have all kinds of combinations. We can get a blue nevus with a spitz nevus. We can get balloon cell nevi. Those are combined nevi because you usually have a population of banal appearing melanocytes and balloon melanocytes. At that point, inactivated melanocytic tumors are frequently combined nevi, commonly characterized by banal nevus and a population of very epithelial spits like melanocytes. So anyway, all possible combinations are... And in actuality, a deep penetrating nevus is frequently combined nevus with a combination of banal nevus and what looks oftentimes like a cellular blue nevus. So anyway, this is a combined melanocytic nevus.",
"med_umls_ids": "[[{'entity': 'Combined', 'concept_id': 'C0205195', 'confidence': 1.0}, {'entity': 'melanocytic nevus', 'concept_id': 'C0027962', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'benign nevus', 'concept_id': 'C1456781', 'confidence': 1.0}, {'entity': 'blue nevus', 'concept_id': 'C0206736', 'confidence': 1.0}], [{'entity': 'Contains', 'concept_id': 'C0332256', 'confidence': 0.9999999403953552}, {'entity': 'clonal populations', 'concept_id': 'C0032659', 'confidence': 0.8110582232475281}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}], [{'entity': 'combinations', 'concept_id': 'C0453882', 'confidence': 1.0}, {'entity': 'combined', 'concept_id': 'C0205195', 'confidence': 1.0}, {'entity': 'nevi', 'concept_id': 'C0027960', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_615",
"caption_rating": "8"
},
{
"": "1004899",
"caption": "There are several melanocytes present, some forming nests and extending into the upper portions of the matrix in a pagetoid pattern.",
"image_path": "8S4LeiO6Bbk_image_0745588b-e17e-42b4-a6c0-d598f293a979.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['nail bed', 'matrix epithelium', 'melanocytes forming nests', 'pagetoid pattern', 'basal layer of the matrix', 'upper portions of the matrix']",
"noisy_text": " we've got nail bed and matricle epithelium. I believe this must be some nail fold, a portion of the nail fold, and then in the bottom piece of tissue in these sections we actually have matricle epithelium and you can see the rete or somewhat hyperplastic. And on higher power examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matricle epithelium in the matricle layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that",
"corrected_text": " we've got nail bed and matrix epithelium. I believe this must be some nail fold, a portion of the nail fold, and then in the bottom piece of tissue in these sections we actually have matrix epithelium and you can see the rete or somewhat hyperplastic. And on higher power examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matrix epithelium in the matrix layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that",
"med_umls_ids": "[[{'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'nail', 'concept_id': 'C0027342', 'confidence': 1.0}, {'entity': 'matrix epithelium', 'concept_id': 'C0014609', 'confidence': 0.7584323883056641}], [{'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'nests', 'concept_id': 'C0035253', 'confidence': 0.7275967001914978}, {'entity': 'upper portions', 'concept_id': 'C0449719', 'confidence': 0.6251541972160339}, {'entity': 'matrix', 'concept_id': 'C0331858', 'confidence': 1.0}, {'entity': 'pagetoid', 'concept_id': 'C1518847', 'confidence': 0.8801172375679016}, {'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}], [{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'matrix layer', 'concept_id': 'C0331858', 'confidence': 0.71736741065979}, {'entity': 'suspicious', 'concept_id': 'C0750493', 'confidence': 1.0}, {'entity': 'melanoma', 'concept_id': 'C0025202', 'confidence': 1.0}, {'entity': 'in situ', 'concept_id': 'C0444498', 'confidence': 0.9999999403953552}]]",
"magnification": "1.0",
"height": "758.0",
"width": "1920.0",
"id": "test_616",
"caption_rating": "9"
},
{
"": "1006543",
"caption": "Proliferation of thin-walled vascular channels of variable size towards the fetal surface of the placenta.",
"image_path": "PJX3uZ7fRn4_image_f749ca24-e5b0-46f3-ac60-273091bcb4e3.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gynecologic', 'Soft tissue', 'Hematopathology']",
"roi_text": "['vascular channels', 'chorionic villi', 'calcification', 'vascular channels', 'chorionic villi', 'calcification']",
"noisy_text": " This is a section from placenta which shows a large irregular area with proliferation of thin walled vascular channels of variable size towards the fetal surface of placenta. Smaller chorionic villi can be seen towards the maternal site. Higher magnification of the same showing large vascular channels in the chorion filled with blood. Still higher magnification showing intercommunicating slit-like vascular spaces in the mass. Focal area of calcification can be seen in the tumor. Still another area",
"corrected_text": " This is a section from placenta which shows a large irregular area with proliferation of thin walled vascular channels of variable size towards the fetal surface of placenta. smaller chorionic villi are not incorrect can be seen towards the maternal site. Higher magnification of the same showing large vascular channels in the chorion filled with blood. Still higher magnification showing intercommunicating slit-like vascular spaces in the mass. Focal area of calcification can be seen in the tumor. Still another area",
"med_umls_ids": "[[{'entity': 'Proliferation', 'concept_id': 'C0334094', 'confidence': 1.0}, {'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}, {'entity': 'variable size', 'concept_id': 'C1866144', 'confidence': 0.8559831976890564}, {'entity': 'fetal', 'concept_id': 'C0015965', 'confidence': 1.0}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'placenta', 'concept_id': 'C0032043', 'confidence': 1.0}], [{'entity': 'chorionic villi', 'concept_id': 'C0008508', 'confidence': 1.0}, {'entity': 'maternal site', 'concept_id': 'C0026591', 'confidence': 0.7640593647956848}], [{'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}, {'entity': 'chorion', 'concept_id': 'C0008503', 'confidence': 0.9999998807907104}, {'entity': 'blood', 'concept_id': 'C0005767', 'confidence': 1.0}], [{'entity': 'Intercommunicating', 'concept_id': 'C0205196', 'confidence': 0.8271207213401794}, {'entity': 'vascular spaces', 'concept_id': 'C0225983', 'confidence': 0.819495439529419}, {'entity': 'mass', 'concept_id': 'C0577559', 'confidence': 1.0}], [{'entity': 'Focal area', 'concept_id': 'C0205234', 'confidence': 0.7634891271591187}, {'entity': 'calcification', 'concept_id': 'C0006660', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_617",
"caption_rating": "9"
},
{
"": "1008348",
"caption": "Epithelial growth within a single gland is observed, connecting the other side of the lumen.",
"image_path": "r7OA0Trj5hQ_image_bee456fa-6f54-4e64-9f71-42d805a33b94.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Loss of cellular polarity in the stratified region', 'Cribriform pattern', 'Intraluminal proliferation of the epithelium within a single gland.', 'Intraluminal proliferation of the epithelium within a single gland.']",
"noisy_text": " So there is loss of polarity. Okay, so here also it is stratified, reaching up to the top, and it is showing loss of polarity. And see the cribriformic. And this is a micropapillary process. Since it's a high power, you are not able to appreciate it better. I will show it to you in the other pictures. But here you can see cribriformic. What happens in cribriformic? It is not crowded back to back glands. It is epithelial growth within your gland. This itself is a single gland. Within that gland, this epithelium is growing and connecting the other side of the lumen. So the intra-glandular proliferation of the epithelium is very,",
"corrected_text": " So there is loss of polarity. Okay, so here also it is stratified, reaching up to the top, and it is showing loss of polarity. And see the cribriform. And this is a micropapillary process. Since it's a high power, you are not able to appreciate it better. I will show it to you in the other pictures. But here you can see cribriform. What happens in cribriform? It is not crowded back to back glands. It is epithelial growth within your gland. This itself is a single gland. Within that gland, this epithelium is growing and connecting the other side of the lumen. So the intraluminal proliferation of the epithelium is very,",
"med_umls_ids": "[[{'entity': 'Loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'cellular polarity', 'concept_id': 'C0085304', 'confidence': 1.0}, {'entity': 'stratified region', 'concept_id': 'C0205363', 'confidence': 0.800367534160614}], [{'entity': 'Cribriform pattern', 'concept_id': 'C1333163', 'confidence': 1.0}], [{'entity': 'Epithelial growth', 'concept_id': 'C1271404', 'confidence': 0.8868558406829834}, {'entity': 'single gland', 'concept_id': 'C0037179', 'confidence': 0.775238573551178}, {'entity': 'lumen', 'concept_id': 'C0524461', 'confidence': 0.9999998807907104}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_618",
"caption_rating": "7"
},
{
"": "1007328",
"caption": "The patient in the case has an aggressive tumor with bladder involvement, indicated by a positive digital rectal examination and elevated PSA level.",
"image_path": "iklRyY1nBIE_image_4c883a0b-0900-4bb1-bae0-28e3399d469b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['bladder involvement', 'positive digital rectal examination', 'elevated PSA level', 'aggressive tumor']",
"noisy_text": " There was also some bladder involvement by this tumor. So this was bad news for this gentleman. So the last case I'm going to share before we go to the Q&A is case number 10. Case number 10 is a 58-year-old gentleman with a positive digital rectal examination and elevated PSA level. So right off the bat, you can appreciate that this is an aggressive tumor. It's very busy. It's a very busy slide. And I picked a particular spot for the photo I shared online. And as our world gets smaller, we need to keep an open mind when we",
"corrected_text": " There was also some bladder involvement by this tumor. So this was bad news for this gentleman. So the last case I'm going to share before we go to the Q&A is case number 10. Case number 10 is a 58-year-old gentleman with a positive digital rectal examination and elevated PSA level. So right off the bat, you can appreciate that this is an aggressive tumor. It's very busy. It's a very busy slide. And I picked a particular spot for the photo I shared online. And as our world gets smaller, we need to keep an open mind when we",
"med_umls_ids": "[[{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'aggressive tumor', 'concept_id': 'C0001807', 'confidence': 0.8577925562858582}, {'entity': 'bladder', 'concept_id': 'C0005682', 'confidence': 1.0}, {'entity': 'involvement', 'concept_id': 'C1314939', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'digital rectal examination', 'concept_id': 'C0199900', 'confidence': 1.0}, {'entity': 'elevated', 'concept_id': 'C0205250', 'confidence': 0.9999999403953552}, {'entity': 'PSA', 'concept_id': 'C0138741', 'confidence': 1.0}, {'entity': 'level', 'concept_id': 'C0441889', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_619",
"caption_rating": "8"
},
{
"": "1006388",
"caption": "Spindle cell non-epithelial neoplasms include muscle and neural tumors.",
"image_path": "LlPaENuqzVQ_image_ee45ecf0-e378-4efd-8115-209e7bb188d8.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['smooth muscle', 'skeletal muscle', 'spindle cell non-epithelial neoplasms', 'atypical fibroxanthoma', 'neural tumors']",
"noisy_text": " So basically, just to kind of go backwards, more generic, muscle. Yeah. Do it. OK. And then there's two types of muscle, right? There's smooth muscle, or three, cardiac muscle, hopefully, to see that in the skin. But smooth and skeletal muscle, which we hardly ever see skeletal muscle neoplasms in dermatology. So it's almost always smooth muscle when we're looking at muscle. And there's probably really only two or three spindle cell non-epithelial neoplasms you need to know about. So muscle's one. What are the other two, basically? Like AFX? Yeah, but more generic. So what's the differentiation in an atypical fibrous anthoma? Just think of the cells that have become malignant in that. They're obviously not muscle cells. Neural? Neural's the other one. Those are the three major ones. But the one that you're missing is the center one there. What else lives in your dermis normally here? So we're going to go back. Fibroblast. Yeah,",
"corrected_text": " So basically, just to kind of go backwards, more generic, muscle. Yeah. Do it. OK. And then there's two types of muscle, right? There's smooth muscle, or three, cardiac muscle, hopefully, to see that in the skin. But smooth and skeletal muscle, which we hardly ever see skeletal muscle neoplasms in dermatology. So it's almost always smooth muscle when we're looking at muscle. And there's probably really only two or three spindle cell non-epithelial neoplasms you need to know about. So muscle's one. What are the other two, basically? Like AFX? Yeah, but more generic. So what's the differentiation in an atypical fibroxanthoma? Just think of the cells that have become malignant in that. They're obviously not muscle cells. Neural? Neural's the other one. Those are the three major ones. But the one that you're missing is the center one there. What else lives in your dermis normally here? So we're going to go back. Fibroblast. Yeah,",
"med_umls_ids": "[[{'entity': 'Smooth', 'concept_id': 'C0205357', 'confidence': 1.0}, {'entity': 'skeletal muscle', 'concept_id': 'C0242692', 'confidence': 1.0}, {'entity': 'muscle', 'concept_id': 'C0026845', 'confidence': 1.0}, {'entity': 'smooth muscle', 'concept_id': 'C1267092', 'confidence': 1.0}, {'entity': 'dermatology', 'concept_id': 'C0011627', 'confidence': 1.0}], [{'entity': 'Spindle cell', 'concept_id': 'C0682540', 'confidence': 0.9999999403953552}, {'entity': 'non-epithelial neoplasms', 'concept_id': 'C1368683', 'confidence': 0.8066584467887878}, {'entity': 'muscle', 'concept_id': 'C0026845', 'confidence': 1.0}, {'entity': 'neural tumors', 'concept_id': 'C1334956', 'confidence': 0.849646270275116}], [{'entity': 'Atypical fibroxanthoma', 'concept_id': 'C0346053', 'confidence': 1.0}, {'entity': 'malignant tumor', 'concept_id': 'C0006826', 'confidence': 1.0}, {'entity': 'muscle cells', 'concept_id': 'C0596981', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_620",
"caption_rating": "8"
},
{
"": "1004520",
"caption": "Inflammation consists of histiocytes, plasma cells, neutrophils, and lymphocytes in the lamina propria.",
"image_path": "sDFjOtMAYrk_image_57e4dcdd-95ed-430b-a7bd-89dff554c7d0.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['inflammation', 'histiocytes', 'plasma cells', 'neutrophils', 'lymphocytes', 'cryptitis']",
"noisy_text": " This is what I'm used to seeing in patients with STI proctitis, just a little bit in the way of inflammation, maybe some cryptitis here and there, but not to the degree that we saw in the previous case. The inflammation consists of, in the lamina propria, some histiocytes, plasma cells, and some neutrophils and lymphocytes. And some cases have predominantly plasma cells in the lamina propria. Some cells have predominantly histiocytes in the lamina propria. I used to think when we started recognizing these that",
"corrected_text": " This is what I'm used to seeing in patients with STI proctitis, just a little bit in the way of inflammation, maybe some cryptitis here and there, but not to the degree that we saw in the previous case. The inflammation consists of, in the lamina propria, some histiocytes, plasma cells, and some neutrophils and lymphocytes. And some cases have predominantly plasma cells in the lamina propria. Some cells have predominantly histiocytes in the lamina propria. I used to think when we started recognizing these that",
"med_umls_ids": "[[{'entity': 'Patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'STI', 'concept_id': 'C0036916', 'confidence': 1.0}, {'entity': 'proctitis', 'concept_id': 'C0033246', 'confidence': 0.9999999403953552}, {'entity': 'mild', 'concept_id': 'C1513302', 'confidence': 1.0}, {'entity': 'inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}, {'entity': 'cryptitis', 'concept_id': 'C1394254', 'confidence': 0.9999998807907104}], [{'entity': 'Inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_621",
"caption_rating": "9"
},
{
"": "1008520",
"caption": "The lesion is a localized, circumscribed area without granulomatous abnormalities or dyskeratotic keratinocytes, ruling out porokeratosis.",
"image_path": "udoW6VSqsm4_image_e9958770-87f7-412e-ace5-f8aafa60a9e6.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['loss of the cornified layer']",
"noisy_text": " And so, the other things we kind of talked about are a bit differential, but next slide. Nothing else really will give you this kind of localized circumscribed area like this, so it's not poro. That would have a coronal lamella with granulocidal abnormalities and dyskeratonic keratinocytes. We don't see that here, so this is just a loss of the coronified layer. And there's one other condition where you kind of get, where are some other little clonal, you know, somatic mutations that you can get abnormalities in the epithelium that occur just in localized areas. That's not like loss of the coronified layer. We'll put a couple of other diseases where you see just local areas that are abnormal, and you get normal skin to the side. So, poro is one. We'll put",
"corrected_text": " And so, the other things we kind of talked about are a bit differential, but next slide. Nothing else really will give you this kind of localized circumscribed area like this, so it's not poro. That would have a coronal lamella with granulomatous abnormalities and dyskeratotic keratinocytes. We don't see that here, so this is just a loss of the cornified layer. And there's one other condition where you kind of get, where are some other little clonal, you know, somatic mutations that you can get abnormalities in the epithelium that occur just in localized areas. That's not like loss of the cornified layer. We'll put a couple of other diseases where you see just local areas that are abnormal, and you get normal skin to the side. So, poro is one. We'll put",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'localized', 'concept_id': 'C0392752', 'confidence': 1.0}, {'entity': 'circumscribed area', 'concept_id': 'C1282914', 'confidence': 0.9260231852531433}, {'entity': 'granulomatous abnormalities', 'concept_id': 'C0439667', 'confidence': 0.7099277377128601}, {'entity': 'dyskeratotic keratinocytes', 'concept_id': 'C1512099', 'confidence': 0.9701507091522217}, {'entity': 'porokeratosis', 'concept_id': 'C0162839', 'confidence': 1.0}], [{'entity': 'loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'cornified layer', 'concept_id': 'C3554359', 'confidence': 0.8562335968017578}], [{'entity': 'conditions', 'concept_id': 'C0012634', 'confidence': 0.8556983470916748}, {'entity': 'localized', 'concept_id': 'C0392752', 'confidence': 1.0}, {'entity': 'abnormality', 'concept_id': 'C1704258', 'confidence': 1.0}, {'entity': 'somatic mutations', 'concept_id': 'C0544886', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_622",
"caption_rating": "9"
},
{
"": "1006847",
"caption": "The biopsy is from an acral site and shows a dome-shaped papule.",
"image_path": "8S4LeiO6Bbk_image_76bedbf1-de38-4994-8b90-f18fe5735913.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['dome-shaped papule', 'acral site', 'thick stratum corneum', 'absence of hair follicles', 'fibrovascular core', 'nerve fascicles', 'spindle-shaped cells', 'S100', 'SOX10', 'rudimentary supernumerary digit']",
"noisy_text": " we've got a dome-shaped papule and that the biopsy is from an acral site. Notice that we've got a very very thick stratum corneum and a marked to virtual absence of hair follicles within the specimen. We do have kind of this fibrovascular core and of course in the center of the fibrovascular core here we've got several well-defined nerve fascicles and the spindled cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions",
"corrected_text": " we've got a dome-shaped papule and that the biopsy is from an acral site. Notice that we've got a very very thick stratum corneum and a marked to virtual absence of hair follicles within the specimen. We do have kind of this fibrovascular core and of course in the center of the fibrovascular core here we've got several well-defined nerve fascicles and the spindle cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions",
"med_umls_ids": "[[{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'acral site', 'concept_id': 'C0439746', 'confidence': 0.717435359954834}, {'entity': 'dome-shaped papule', 'concept_id': 'C1711316', 'confidence': 0.752353847026825}], [{'entity': 'specimen', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'stratum corneum', 'concept_id': 'C0221921', 'confidence': 1.0}, {'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'hair follicles', 'concept_id': 'C0221971', 'confidence': 0.9999998807907104}], [{'entity': 'fibrovascular', 'concept_id': 'C0392759', 'confidence': 1.0}, {'entity': 'nerve fascicles', 'concept_id': 'C1185741', 'confidence': 0.8332967758178711}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'S100', 'concept_id': 'C3273837', 'confidence': 1.0}, {'entity': 'SOX10', 'concept_id': 'C1420317', 'confidence': 0.9999998807907104}, {'entity': 'neural tumor', 'concept_id': 'C1334956', 'confidence': 1.0}], [{'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'rudimentary supernumerary digit', 'concept_id': 'C0152427', 'confidence': 0.8142021894454956}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_623",
"caption_rating": "8"
},
{
"": "1005191",
"caption": "Description of normal colonic glands and crypts with no lymphocytes, plasma cells, or eosinophils. The amount of lamina propria in between the crypts is the same as you move from one crypt to another.",
"image_path": "sDFjOtMAYrk_image_1973ba9f-6251-4c3e-b486-dd021cff0c72.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['colonic crypts', 'muscularis mucosa', 'lamina propria']",
"noisy_text": " fellows about normal. What I like to see are these colonic glands. Do we have an arrow? Oh, yes. It should. Is he not coming up? No. Oh, you have to turn it on. No, it's not coming up. Yeah, it is. Yeah, here you go. Just the red one. Yeah. Oh, I don't see it. It's okay. Is the mouse going to work? Yeah, I'll do the mouse. Yeah, it works. Okay. Basically, I like to see my colonic crypts nice and straight coming from the surface, trying to kiss that muscularis mucosa underneath in between the crypts and the muscularis mucosa. I don't want to see any lymphocytes, plasma cells, eosinophils. You can have one or two. That's okay, but typically no basal lymphoplasma cytosis. The other thing I like to point out is the amount of lamina propria in between the crypts is the same as you move from one crypt to another. The crypts stand equidistant one from another. Remember the differences between the cecum or the right colon and the left colon. This is a biopsy from the segment and shows",
"corrected_text": " fellows about normal. What I like to see are these colonic glands. Do we have an arrow? Oh, yes. It should. Is he not coming up? No. Oh, you have to turn it on. No, it's not coming up. Yeah, it is. Yeah, here you go. Just the red one. Yeah. Oh, I don't see it. It's okay. Is the mouse going to work? Yeah, I'll do the mouse. Yeah, it works. Okay. Basically, I like to see my colonic crypts nice and straight coming from the surface, trying to kiss that muscularis mucosa underneath in between the crypts and the muscularis mucosa. I don't want to see any lymphocytes, plasma cells, eosinophils. You can have one or two. That's okay, but typically no basal lymphoplasma cytosis. The other thing I like to point out is the amount of lamina propria in between the crypts is the same as you move from one crypt to another. The crypts stand equidistant one from another. Remember the differences between the cecum or the right colon and the left colon. This is a biopsy from the segment and shows",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'colonic glands', 'concept_id': 'C0227351', 'confidence': 0.8191195130348206}, {'entity': 'crypts', 'concept_id': 'C0227427', 'confidence': 0.9071587324142456}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'amount', 'concept_id': 'C1265611', 'confidence': 0.9999998807907104}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'crypts', 'concept_id': 'C0227427', 'confidence': 0.9071587324142456}, {'entity': 'crypt', 'concept_id': 'C1880192', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_624",
"caption_rating": "9"
},
{
"": "1005091",
"caption": "The lesion appears neoplastic and epithelial in nature",
"image_path": "LlPaENuqzVQ_image_e71912cb-260c-4170-9a37-ecb328b6dddc.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['The lesion is not well circumscribed and appears asymmetrical', 'The size of the lesion is large', 'The lesion is not well circumscribed and appears asymmetrical', 'The size of the lesion is large']",
"noisy_text": " So they basically took the elliptical excision. They cut it into bread loaves and put it all on one slide. So that's how they did this in this case, because yeah, if you do a shave, how frequently do you get down to the bottom of the subcutaneous fat? That's pretty rare. So this is an excisional biopsy. Good. And are you dealing with an inflammatory or neoplastic process? Looks more neoplastic. Good, good. Epithelial or non-epithelial? Epithelioid. Good, epithelial. Benign or malignant? It's not very well prescribed. You can do it low power, isn't it? It's phenomenal. You can really get it down pretty well if you just apply the criteria. So you like benign or malignant here? It's not very well circumscribed, and it looks like there's some erosion on top. That may be from a prior biopsy, interestingly enough. But yeah, look at its symmetry. Is this symmetrical? Not really. No, no, no. It's pretty big. This is",
"corrected_text": " So they basically took the elliptical excision. They cut it into bread loaves and put it all on one slide. So that's how they did this in this case, because yeah, if you do a shave, how frequently do you get down to the bottom of the subcutaneous fat? That's pretty rare. So this is an excisional biopsy. Good. And are you dealing with an inflammatory or neoplastic process? Looks more neoplastic. Good, good. Epithelial or non-epithelial? epithelial. Good, epithelial. Benign or malignant? It's not very well prescribed. You can do it low power, isn't it? It's phenomenal. You can really get it down pretty well if you just apply the criteria. So you like benign or malignant here? It's not very well circumscribed, and it looks like there's some erosion on top. That may be from a prior biopsy, interestingly enough. But yeah, look at its symmetry. Is this symmetrical? Not really. No, no, no. It's pretty big. This is",
"med_umls_ids": "[[{'entity': 'Elliptical excision', 'concept_id': 'C1707902', 'confidence': 0.8901858329772949}, {'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}], [{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'neoplastic', 'concept_id': 'C1709160', 'confidence': 0.9999999403953552}, {'entity': 'epithelial', 'concept_id': 'C0221908', 'confidence': 1.0}], [{'entity': 'Malignancy', 'concept_id': 'C0006826', 'confidence': 1.0}, {'entity': 'determined with', 'concept_id': 'C0521095', 'confidence': 0.8590028285980225}, {'entity': 'certainty', 'concept_id': 'C0205423', 'confidence': 1.0}], [{'entity': 'erosion', 'concept_id': 'C0333307', 'confidence': 1.0}, {'entity': 'top', 'concept_id': 'C1420726', 'confidence': 1.0}, {'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_625",
"caption_rating": "8"
},
{
"": "1008430",
"caption": "The cells in the nevus are type A melanocytes, which are vesicular in appearance. This is a nevoid melanoma.",
"image_path": "zhzJ9pgCvuw_image_03e35331-8aa2-4878-94dd-24ffdd5ddbd0.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Hematopathology']",
"roi_text": "['Nevus cells at the top', 'Type A melanocytes']",
"noisy_text": " nevus at the top you'd have type a nevus cells down at the bottom if this was a nevus in an old portion you'd probably have type c nevus cells where they look neural and they'd at least be type b where there'd be hyperchromatic nuclei and no cytoplasm but these these nevus cells or these melanocytes are vesicular that you like they're type a cells uh so you add all that up and this is what it is this is a nevoid melanoma no i'm not going to go gazing looking for mitotic triggers but uh they they they will be there if not in this section they'll be present",
"corrected_text": " nevus at the top you'd have type a nevus cells down at the bottom if this was a nevus in an old portion you'd probably have type c nevus cells where they look neural and they'd at least be type b where there'd be hyperchromatic nuclei and no cytoplasm but these these nevus cells or these melanocytes are vesicular that you like they're type a cells uh so you add all that up and this is what it is this is a nevoid melanoma no i'm not going to go gazing looking for mitotic triggers but uh they they they will be there if not in this section they'll be present",
"med_umls_ids": "[[{'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'nevus', 'concept_id': 'C0027960', 'confidence': 0.9999998807907104}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'vesicular', 'concept_id': 'C0205378', 'confidence': 1.0}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'nevoid melanoma', 'concept_id': 'C1882081', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_626",
"caption_rating": "8"
},
{
"": "1004741",
"caption": "The patient was treated for sarcoidosis and subsequent biopsies showed no more granulomas.",
"image_path": "sDFjOtMAYrk_image_2211d8b3-d4db-4cd5-969d-76137a607896.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['uveitis with characteristic features', 'granulomas in sarcoidosis and Crohn\u2019s disease']",
"noisy_text": " patient had sarcoid. So I said, this is probably not IBD, clinicians came down, we want to look at the biopsy, of course. It turns out that they went back and talked to the patient. The patient has a history of uveitis with characteristic features that were good for sarcoidosis. Nobody knew about they treated the patient for sarcoid, re-biopsied the patient. And he was fine. There were no more granulomas on multiple repeat biopsies. And now compare those grannies with the grannies in Crohn's. So here's a giant cell right there, but there was a better one right there. So they're like kind of",
"corrected_text": " patient had sarcoid. So I said, this is probably not IBD, clinicians came down, we want to look at the biopsy, of course. It turns out that they went back and talked to the patient. The patient has a history of uveitis with characteristic features that were good for sarcoidosis. Nobody knew about they treated the patient for sarcoid, re-biopsied the patient. And he was fine. There were no more granulomas on multiple repeat biopsies. And now compare those grannies with the grannies in Crohn's. So here's a giant cell right there, but there was a better one right there. So they're like kind of",
"med_umls_ids": "[[{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'suspected', 'concept_id': 'C0332147', 'confidence': 1.0}, {'entity': 'IBD', 'concept_id': 'C0021390', 'confidence': 1.0}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'history', 'concept_id': 'C0019664', 'confidence': 1.0}, {'entity': 'uveitis', 'concept_id': 'C0042164', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'treated', 'concept_id': 'C1522326', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'biopsies', 'concept_id': 'C0005558', 'confidence': 1.0}, {'entity': 'granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}], [{'entity': 'Comparison', 'concept_id': 'C1707455', 'confidence': 1.0}, {'entity': 'granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'Crohn\u2019s disease', 'concept_id': 'C0010346', 'confidence': 0.8916962146759033}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_627",
"caption_rating": "8"
},
{
"": "1008317",
"caption": "Histopathological description of a skin condition with predominance of histiocytes and lymphocytes.",
"image_path": "LlPaENuqzVQ_image_4619fb4f-a724-4098-99be-ac57f694e50b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['face', 'follicular pustule', 'histiocytes', 'lymphocytes', 'face', 'follicular pustule', 'histiocytes', 'lymphocytes']",
"noisy_text": " Oh, maybe there are some there on the other slide. But, oh, yeah, there's some. Not a lot, but, you know, there's mostly histiocytes predominated with lymphocytes. There's a couple of eos, but it's not... There aren't a lot. So that kind of made me think of granulomatous rosacea. Good. Excellent. That's exactly what it should make you think of. Very, very good. That's exactly what this is. So the face helps you, right? You're not going to see this on somebody's trunk. The follicular pustule helps too, right? Because rosacea can give you multiple different histologic reaction patterns. What are some of the forms of rosacea? So we've got two forms here. We've got papulopustular rosacea. We've got granulomatous rosacea. What are a couple other forms of rosacea? You could just have an ET type of just, you know, kind of like telangiectasia. Yes, good. The telangiectatic type of rosacea. What's one other one that we get sometimes? I guess there's other... I mean, I don't",
"corrected_text": " Oh, maybe there are some there on the other slide. But, oh, yeah, there's some. Not a lot, but, you know, there's mostly histiocytes predominated with lymphocytes. There's a couple of eos, but it's not... There aren't a lot. So that kind of made me think of granulomatous rosacea. Good. Excellent. That's exactly what it should make you think of. Very, very good. That's exactly what this is. So the face helps you, right? You're not going to see this on somebody's trunk. The follicular pustule helps too, right? Because rosacea can give you multiple different histologic reaction patterns. What are some of the forms of rosacea? So we've got two forms here. We've got papulopustular rosacea. We've got granulomatous rosacea. What are a couple other forms of rosacea? You could just have an ET type of just, you know, kind of like telangiectasia. Yes, good. The telangiectatic type of rosacea. What's one other one that we get sometimes? I guess there's other... I mean, I don't",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'skin condition', 'concept_id': 'C1719933', 'confidence': 1.0}, {'entity': 'predominance', 'concept_id': 'C1835590', 'confidence': 0.8840479850769043}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}], [{'entity': 'Granulomatous rosacea', 'concept_id': 'C1275718', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'Rosacea', 'concept_id': 'C0035854', 'confidence': 1.0}, {'entity': 'multiple', 'concept_id': 'C0439064', 'confidence': 1.0}, {'entity': 'histologic reaction', 'concept_id': 'C0205462', 'confidence': 0.8118124008178711}, {'entity': 'papulopustular rosacea', 'concept_id': 'C1449853', 'confidence': 1.0}, {'entity': 'telangiectatic type', 'concept_id': 'C4014149', 'confidence': 0.7599172592163086}, {'entity': 'rosacea', 'concept_id': 'C0035854', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_628",
"caption_rating": "8"
},
{
"": "1008402",
"caption": "The process is infiltrating between benign glands and respecting them, which is a clue to the diagnosis.",
"image_path": "iklRyY1nBIE_image_6973991a-dbd2-4da3-a04b-d92d64c46031.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['basal cell hyperplasia', 'infiltrating between benign glands', 'STOMP', 'prostatic stroma of sarcoma', 'HMB45 melanin', 'S100', 'STAT6', 'basal cell hyperplasia', 'infiltrating between benign glands', 'STOMP', 'prostatic stroma of sarcoma', 'HMB45 melanin', 'S100', 'STAT6']",
"noisy_text": " Something else you may have observed with this case is the fact that it's not just a stroma process. It looks like there's something else going on in the glands, too. And in the glands, it's almost like there's a crosstalk between the stroma process and the glands. The glands are benign, but they actually have what looks like basal cell hyperplasia in areas. And that's not uncommon with this entity. It is not unusual to have this entity, actually, with basal cell hyperplasia. The other observation I want to bring to your attention is the fact that this process is going in between benign glands, which means that it's almost respecting the benign glands next door. Because there are a number of processes that would destroy the adjacent benign glands and basically push them aside. But this process actually respects the benign glands, in quotes, and is actually going in between them, infiltrating in between them. And that's a clue to the diagnosis. Because as I hinted earlier, when you talk of tumors of the specialized prosthetic stroma, there are two main entities you think about. One is the so-called STOMP, stromal tumor of unsaturated malignant potential. And the other entity at the other extreme is the so-called prosthetic stroma of sarcoma. Some argue that there's some relationship between both of them that are in the spectrum. But what you're looking at right now in this case, based on what I've shown you, this type of atypia, it almost looks simplistic. It has this degenerative type of look to it. We are not seeing mitotic activity. For something this ugly or that looks this nasty, you'll expect to see necrosis, mitotic activity, and even destruction of the adjacent glands. But we're not seeing that. And that's kind of a perfect picture for so-called STOMP, stromal tumor of unsaturated malignant potential. As I said earlier, there's a relationship between this entity and prosthetic stroma of sarcoma. To start with, STOMPs can recur. About 15% of STOMPs can recur months or years after the initial resection. But about 15% to 20% of STOMPs may progress or may be associated with adjacent prosthetic stroma of sarcoma. So that's a very important thing to know. Because STOMP itself, as the name implies, is of unsaturated malignant potential. So it should not be downplayed. Because some of you may ask me, how do I sign all these cases? It's very important in your comments to document what I just said, that about 15% of these, if it's just STOMP is here on the H&E, nothing else, it's important to document that about 15% would recur. And more importantly, it's important to document that about 15% to 20% of these may be associated with or progress to prosthetic stroma of sarcoma. So it's not a case of they excise this and they leave the patient alone. They need to follow up these patients very closely. So that's very important to document in the report. So some of you may ask, OK, so what stains do we do for these cases? Obviously, you want to exclude a number of things. We talked about melanoma and other things. So you want to exclude those. So obviously, HMB45 melanin, those will be negative. Vimentin, which nobody uses anymore, is actually positive in this entity. PR could also be positive in this entity. Plus or minus CD34, plus or minus Desmin SMA, plus or minus ER may be positive, but it's usually negative. The pertinent negative stains are S100. I talked about the melanoma markers. And STAT6 is also negative. So it's very important to know that. So this is a stromal tumor of uncertain malignant potential. There have been a number of names for this entity over the years.",
"corrected_text": " Something else you may have observed with this case is the fact that it's not just a stroma process. It looks like there's something else going on in the glands, too. And in the glands, it's almost like there's a crosstalk between the stroma process and the glands. The glands are benign, but they actually have what looks like basal cell hyperplasia in areas. And that's not uncommon with this entity. It is not unusual to have this entity, actually, with basal cell hyperplasia. The other observation I want to bring to your attention is the fact that this process is going in between benign glands, which means that it's almost respecting the benign glands next door. Because there are a number of processes that would destroy the adjacent benign glands and basically push them aside. But this process actually respects the benign glands, in quotes, and is actually going in between them, infiltrating in between them. And that's a clue to the diagnosis. Because as I hinted earlier, when you talk of tumors of the specialized prosthetic stroma, there are two main entities you think about. One is the so-called STOMP, stromal tumor of unsaturated malignant potential. And the other entity at the other extreme is the so-called prosthetic stroma of sarcoma. Some argue that there's some relationship between both of them that are in the spectrum. But what you're looking at right now in this case, based on what I've shown you, this type of atypia, it almost looks simplistic. It has this degenerative type of look to it. We are not seeing mitotic activity. For something this ugly or that looks this nasty, you'expect to see necrosis, mitotic activity, and even destruction of the adjacent glands. But we're not seeing that. And that's kind of a perfect picture for so-called STOMP, stromal tumor of unsaturated malignant potential. As I said earlier, there's a relationship between this entity and prosthetic stroma of sarcoma. To start with, STOMPs can recur. About 15% of STOMPs can recur months or years after the initial resection. But about 15% to 20% of STOMPs may progress or may be associated with adjacent prosthetic stroma of sarcoma. So that's a very important thing to know. Because STOMP itself, as the name implies, is of unsaturated malignant potential. So it should not be downplayed. Because some of you may ask me, how do I sign all these cases? It's very important in your comments to document what I just said, that about 15% of these, if it's just STOMP is here on the H&E, nothing else, it's important to document that about 15% would recur. And more importantly, it's important to document that about 15% to 20% of these may be associated with or progress to prosthetic stroma of sarcoma. So it's not a case of they excise this and they leave the patient alone. They need to follow up these patients very closely. So that's very important to document in the report. So some of you may ask, OK, so what stains do we do for these cases? Obviously, you want to exclude a number of things. We talked about melanoma and other things. So you want to exclude those. So obviously, HMB45 melanin, those will be negative. Vimentin, which nobody uses anymore, is actually positive in this entity. PR could also be positive in this entity. Plus or minus CD34, plus or minus Desmin SMA, plus or minus ER may be positive, but it's usually negative. The pertinent negative stains are S100. I talked about the melanoma markers. And STAT6 is also negative. So it's very important to know that. So this is a stromal tumor of uncertain malignant potential. There have been a number of names for this entity over the years.",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'basal cell', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'benign glands', 'concept_id': 'C1301287', 'confidence': 0.726940393447876}, {'entity': 'entity', 'concept_id': 'C1551338', 'confidence': 1.0}], [{'entity': 'process', 'concept_id': 'C1184743', 'confidence': 1.0}, {'entity': 'infiltrating', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'benign glands', 'concept_id': 'C1301287', 'confidence': 0.726940393447876}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'atypia', 'concept_id': 'C0741302', 'confidence': 0.9999999403953552}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'consistent with', 'concept_id': 'C0332290', 'confidence': 1.0}, {'entity': 'STOMP', 'concept_id': 'C0056167', 'confidence': 0.6245664358139038}, {'entity': 'stromal tumor', 'concept_id': 'C0879615', 'confidence': 1.0}, {'entity': 'malignant', 'concept_id': 'C0205282', 'confidence': 1.0}, {'entity': 'potential', 'concept_id': 'C3245505', 'confidence': 1.0}], [{'entity': 'STOMPs', 'concept_id': 'C0577018', 'confidence': 0.6140404343605042}, {'entity': 'recur', 'concept_id': 'C0034897', 'confidence': 0.9999999403953552}, {'entity': 'progress', 'concept_id': 'C1272688', 'confidence': 1.0}, {'entity': 'prostatic stroma', 'concept_id': 'C1521760', 'confidence': 0.9999999403953552}, {'entity': 'sarcoma', 'concept_id': 'C1261473', 'confidence': 1.0}], [{'entity': 'Stains', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'entities', 'concept_id': 'C0424215', 'confidence': 0.7521668672561646}, {'entity': 'HMB45', 'concept_id': 'C1440756', 'confidence': 1.0}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}, {'entity': 'S100', 'concept_id': 'C3273837', 'confidence': 1.0}, {'entity': 'STAT6', 'concept_id': 'C0297890', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_629",
"caption_rating": "8"
},
{
"": "1004941",
"caption": "Uniform cells surrounding the edge of the neurofibroma with rosettes, which may indicate a low-grade fibromyxoid sarcoma.",
"image_path": "QDb68_G1HR4_image_71f1eab7-973d-4fce-9257-2955683001f3.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " uniform cells that surround the edge of the collagen rosettes when you see those rosettes in this tumor so collagen rosettes in a fibroblastic tumor should be an instant clue that you're probably dealing with a low-grade fibromyxoid sarcoma but do remember again that some variants of schwannoma can also have rosettes and so be sure not to confuse those immunostains can help you out there so I hope that you like this video and that this helps sort this out again make sure that you've checked out my you know five-minute approach to telling apart low-grade fibromyxoid sarcoma from myxofibrosarcoma comma grade 1 and also watch the full-length feature video about myxofibrosarcoma and then I think after seeing this video and those two videos you should have a really solid handle on how to tell these tumors apart I made these videos and went so in-depth because I find that that pathologists often really struggle with these because the name sounds so much alike and in those of us in soft tissue pathology who publish papers maybe we haven't helped the general pathology public so much by making names that all sound so similar. So I hope the video has helped if you liked it please click like down below and leave comments or questions in the comment section and of course make sure you subscribe to my channel if you haven't yet so that you'll be notified about new videos that I post in the future.",
"corrected_text": " uniform cells that surround the edge of the collagen rosettes when you see those rosettes in this tumor so collagen rosettes in a fibroblastic tumor should be an instant clue that you're probably dealing with a low-grade fibromyxoid sarcoma but do remember again that some variants of schwannoma can also have rosettes and so be sure not to confuse those immunostains can help you out there so I hope that you like this video and that this helps sort this out again make sure that you've checked out my you know five-minute approach to telling apart low-grade fibromyxoid sarcoma from myxofibrosarcoma comma grade 1 and also watch the full-length feature video about myxofibrosarcoma and then I think after seeing this video and those two videos you should have a really solid handle on how to tell these tumors apart I made these videos and went so detailed because I find that that pathologists often really struggle with these because the name sounds so much alike and in those of us in soft tissue pathology who publish papers maybe we haven't helped the general pathology public so much by making names that all sound so similar. So I hope the video has helped if you liked it please click like down below and leave comments or questions in the comment section and of course make sure you subscribe to my channel if you haven't yet so that you'll be notified about new videos that I post in the future.",
"med_umls_ids": "[[{'entity': 'Uniform cells', 'concept_id': 'C0007584', 'confidence': 0.6272867321968079}, {'entity': 'edge', 'concept_id': 'C0205154', 'confidence': 1.0}, {'entity': 'neurofibroma', 'concept_id': 'C0027830', 'confidence': 1.0}, {'entity': 'rosettes', 'concept_id': 'C0035863', 'confidence': 0.8847858905792236}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}], [{'entity': 'Immunohistochemistry', 'concept_id': 'C0021044', 'confidence': 0.9999998807907104}, {'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_630",
"caption_rating": "8"
},
{
"": "1004362",
"caption": "Glands are equally distant from each other and trying to retain their shapes overall, but there is some architectural distortion.",
"image_path": "sDFjOtMAYrk_image_880addef-67c7-4dc5-9f74-cc5755fdcaba.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['glands are trying to keep their shapes', 'lamina propria is expanded', 'degree of architectural distortion', 'inflammatory lamina propria', 'glands are trying to keep their shapes', 'lamina propria is expanded', 'degree of architectural distortion', 'inflammatory lamina propria']",
"noisy_text": " There's a little bit of distortion. I would give you that. But overall, the glands are trying to keep their distance. They're equally distant one from another and they're trying to keep their shapes overall. I wouldn't say the architecture is perfect, but overall, they're trying to retain it. And you mentioned whether this was from the right or left. And that's a good question. I would say, since this is from the rectum, the lamina propria is actually expanded. So, I would say it's too cellular for rectum. So, I think IBD would be definitely in the differential with that degree of architectural distortion maybe, but with that degree of inflammatory lamina propria expansion. But let's look",
"corrected_text": " There's a little bit of distortion. I would give you that. But overall, the glands are trying to keep their distance. They're equally distant one from another and they're trying to keep their shapes overall. I wouldn't say the architecture is perfect, but overall, they're trying to retain it. And you mentioned whether this was from the right or left. And that's a good question. I would say, since this is from the rectum, the lamina propria is actually expanded. So, I would say it's too cellular for rectum. So, I think IBD would be definitely in the differential with that degree of architectural distortion maybe, but with that degree of inflammatory lamina propria expansion. But let's look",
"med_umls_ids": "[[{'entity': 'Glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'distant', 'concept_id': 'C0443203', 'confidence': 1.0}, {'entity': 'shapes', 'concept_id': 'C0332479', 'confidence': 1.0}, {'entity': 'overall', 'concept_id': 'C0282416', 'confidence': 1.0}, {'entity': 'architectural distortion', 'concept_id': 'C2826609', 'confidence': 1.0}], [{'entity': 'Lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'degree', 'concept_id': 'C0441889', 'confidence': 1.0}, {'entity': 'inflammatory', 'concept_id': 'C0333348', 'confidence': 1.0}, {'entity': 'IBD', 'concept_id': 'C0021390', 'confidence': 1.0}, {'entity': 'differential diagnosis', 'concept_id': 'C0011906', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_631",
"caption_rating": "8"
},
{
"": "1004642",
"caption": "Muscle fibers are seen running into the lamina propria.",
"image_path": "r7OA0Trj5hQ_image_6383bc61-ea49-4ba7-b64c-3752ed875092.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['muscle fibers', 'intestinal metaplasia', 'lamina propria', 'muscle fibers', 'intestinal metaplasia', 'lamina propria']",
"noisy_text": " where, again, you can see the muscle fibers running into the lamina propria. If you are in doubt, you can use the trichrome strain, where you can identify the muscle running up there. And you can see nice intestinal metaplasia there. Again, the number of glands are less in here. So this is chronic atrophic gastritis with intestinal metaplasia with muscularization of the lamina propria. More than one pathology involved in this biopsy. Plastic changes seen above are known as TIS. Once they cross the muscular ischemicosa, then only they are eligible for T1. So muscular ischemicosa acts like",
"corrected_text": " where, again, you can see the muscle fibers running into the lamina propria. If you are in doubt, you can use the trichrome strain, where you can identify the muscle running up there. And you can see nice intestinal metaplasia there. Again, the number of glands are less in here. So this is chronic atrophic gastritis with intestinal metaplasia with muscularization of the lamina propria. More than one pathology involved in this biopsy. Plastic changes seen above are known as TIS. Once they cross the muscularis propria, then only they are eligible for T1. So muscularis propria acts like",
"med_umls_ids": "[[{'entity': 'Muscle fibers', 'concept_id': 'C0242697', 'confidence': 1.0}, {'entity': 'running', 'concept_id': 'C0035953', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}], [{'entity': 'Intestinal metaplasia', 'concept_id': 'C0334037', 'confidence': 1.0}], [{'entity': 'Chronic atrophic gastritis', 'concept_id': 'C0017154', 'confidence': 1.0}, {'entity': 'intestinal metaplasia', 'concept_id': 'C0334037', 'confidence': 1.0}, {'entity': 'muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'Plastic changes', 'concept_id': 'C0392747', 'confidence': 0.7598782777786255}, {'entity': 'TIS', 'concept_id': 'C0475413', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_632",
"caption_rating": "7"
},
{
"": "1008024",
"caption": "Slightly hyperplastic epidermis and a cellular infiltrate throughout the dermis.",
"image_path": "8S4LeiO6Bbk_image_d9437f71-99a7-4b21-84d6-8af77c47cabf.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['infiltrate filling the dermis and extending into the subcutaneous tissue', 'cellular infiltrate throughout the dermis', 'infiltrate filling the dermis and extending into the subcutaneous tissue', 'brown pigment near the surface', 'hyperplastic epidermis', 'cellular infiltrate throughout the dermis']",
"noisy_text": " a large punch biopsy. And I think this actually was two punch biopsies from one lesion, each one bisected. And we can see that we've got an infiltrate filling the dermis and extending into the subcutaneous tissue. The infiltrate appears to be compressing the fat rather than growing in between the adipocytes. And I think it's scanning magnification, you know, one of the things that you can really begin to appreciate, not only the fact that this lesion is partially sampled, that it extends to the base and edges of the specimen, but one can begin to appreciate abundant hemorrhage within this tumor. And in addition, we can see some brown pigment near the surface. And common sense will tell you where there's smoke, there's fire. Since we do have all this abundant hemorrhage, there's a high probability that the pigment, this brownish gold pigment that we're seeing up near the surface of the specimen is likely hemocentaurant rather than melanin. But we'll confirm that when we go down to a higher power. As we move in, we can see that the epidermis is slightly hyperplastic. We've got this cellular infiltrate throughout the dermis and we'll need to go down and take a look at this infiltrate. It appears a little less dense at the",
"corrected_text": " a large punch biopsy. And I think this actually was two punch biopsies from one lesion, each one bisected. And we can see that we've got an infiltrate filling the dermis and extending into the subcutaneous tissue. The infiltrate appears to be compressing the fat rather than growing in between the adipocytes. And I think it's scanning magnification, you know, one of the things that you can really begin to appreciate, not only the fact that this lesion is partially sampled, that it extends to the base and edges of the specimen, but one can begin to appreciate abundant hemorrhage within this tumor. And in addition, we can see some brown pigment near the surface. And common sense will tell you where there's smoke, there's fire. Since we do have all this abundant hemorrhage, there's a high probability that the pigment, this brownish gold pigment that we're seeing up near the surface of the specimen is likely hemocentaurant rather than melanin. But we'confirm that when we go down to a higher power. As we move in, we can see that the epidermis is slightly hyperplastic. We've got this cellular infiltrate throughout the dermis and we'll need to go down and take a look at this infiltrate. It appears a little less dense at the",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'punch biopsy', 'concept_id': 'C0182557', 'confidence': 1.0}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'filling', 'concept_id': 'C0178866', 'confidence': 0.7777882218360901}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'subcutaneous tissue', 'concept_id': 'C0222331', 'confidence': 1.0}], [{'entity': 'Excessive', 'concept_id': 'C0442802', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'brown pigment near', 'concept_id': 'C4555503', 'confidence': 0.865685760974884}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}], [{'entity': 'hyperplastic epidermis', 'concept_id': 'C4748317', 'confidence': 0.7633129358291626}, {'entity': 'cellular infiltrate', 'concept_id': 'C1692321', 'confidence': 1.0}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_633",
"caption_rating": "9"
},
{
"": "1006803",
"caption": "Presence of basal cells at the periphery indicates that the tumor is not invasive.",
"image_path": "iklRyY1nBIE_image_06474144-5c48-46a7-8e65-c93b6249c886.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['basal cells at the periphery', 'enlarged nuclei', 'intraductal carcinoma of the prostate', 'adjacent invasive tumor', 'previously benign gland', 'basal cells at the periphery', 'enlarged nuclei', 'intraductal carcinoma of the prostate', 'adjacent invasive tumor', 'previously benign gland']",
"noisy_text": " Let me show you what the cocktail looks like. Again, this is the pin three, or some call it pin four. You have the P63, you have the hemoglobin cytokeratin, and then you have the racemase, which is the pink chromogen. And as you can see, as I demonstrated on the H&E, basal cells are indeed present. This is too much for high-grade pin. This is basically what is called a solid cribriform kind of pattern, in which over 50% of the lumen is filled by tumor cells. So this is way too much for high-grade pin. But it's not invasive, because you have basal cells at the periphery. And the nuclei are enlarged. These nuclei are about six times the size of normal prostate nuclei. So this case meets the criteria for introductal carcinoma of the prostate. There is an invasive component, which you can see is negative for basal cell markers. But you have the introductal component. And this is a very interesting entity. The vast majority of cases, and I'll show you the corresponding radical prostatectomy specimens in a second, but the vast majority of these so-called introductal carcinoma of the prostate is due to invasion, colonization by adjacent invasive tumor. And it usually occurs in patients that have high-volume tumors. When I show you the corresponding radical prostatectomies, you'll see what I'm talking about. You usually don't have this in patients in their radicals that have 5% prostate cancer or 10% prostate cancer. It's usually patients that have extensive prostate cancer involvement, and the invasive glands basically have nowhere else to go but to colonize adjacent benign glands. And I'll demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues,",
"corrected_text": " Let me show you what the cocktail looks like. Again, this is the pin three, or some call it pin four. You have the P63, you have the hemoglobin cytokeratin, and then you have the racemase, which is the AMACR. And as you can see, as I demonstrated on the H&E, basal cells are indeed present. This is too much for high-grade pin. This is basically what is called a solid cribriform kind of pattern, in which over 50% of the lumen is filled by tumor cells. So this is way too much for high-grade pin. But it's not invasive, because you have basal cells at the periphery. And the nuclei are enlarged. These nuclei are about six times the size of normal prostate nuclei. So this case meets the criteria for intraductal carcinoma of the prostate. There is an invasive component, which you can see is negative for basal cell markers. But you have the intraductal component. And this is a very interesting entity. The vast majority of cases, and I'll show you the corresponding radical prostatectomy specimens in a second, but the vast majority of these so-called intraductal carcinoma of the prostate is due to invasion, colonization by adjacent invasive tumor. And it usually occurs in patients that have high-volume tumors. When I show you the corresponding radical prostatectomies, you'll see what I'm talking about. You usually don't have this in patients in their radicals that have 5% prostate cancer or 10% prostate cancer. It's usually patients that have extensive prostate cancer involvement, and the invasive glands basically have nowhere else to go but to colonize adjacent benign glands. And I'demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues,",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'cocktail', 'concept_id': 'C0678420', 'confidence': 1.0}, {'entity': 'markers', 'concept_id': 'C0181734', 'confidence': 0.890313982963562}, {'entity': 'intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate diagnosis', 'concept_id': 'C0011900', 'confidence': 0.7927443981170654}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'basal cells', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}], [{'entity': 'Enlarged nuclei', 'concept_id': 'C4013177', 'confidence': 0.7774685621261597}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'normal', 'concept_id': 'C0205307', 'confidence': 1.0}], [{'entity': 'Intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'invasion', 'concept_id': 'C1269955', 'confidence': 1.0}, {'entity': 'colonization', 'concept_id': 'C4289767', 'confidence': 1.0}, {'entity': 'adjacent', 'concept_id': 'C0205117', 'confidence': 1.0}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}], [{'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'benign gland', 'concept_id': 'C0205183', 'confidence': 0.7986565828323364}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_634",
"caption_rating": "8"
},
{
"": "1007066",
"caption": "Unique collagen pattern seen in a particular tumor, possibly related to hyalinization in collagen seen around smaller vessels.",
"image_path": "QDb68_G1HR4_image_fdb04429-baf7-424c-aa57-212bda9c4184.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " flipped here you can see this unique collagen pattern in this particular tumor. And I don't know but I kind of suspect that these collagen rosettes may be related to the hyalinization in collagen that we see around smaller vessels like I showed in that tumor the example earlier that this may just be a more dramatic example. Now one other tumor that might enter the differential here is the so-called neuroblastoma-like variant of schwannoma or neurilomoma neuroblastoma-like schwannoma. It has also big collagen rich rosettes like this but it has a much more prominent round cell appearance around the edge of the rim of the nodules are very like small round blue cell almost",
"corrected_text": " flipped here you can see this unique collagen pattern in this particular tumor. And I don't know but I kind of suspect that these collagen rosettes may be related to the hyalinization in collagen that we see around smaller vessels like I showed in that tumor the example earlier that this may just be a more dramatic example. Now one other tumor that might enter the differential here is the so-called neuroblastoma-like variant of schwannoma or neurilomoma neuroblastoma-like schwannoma. It has also big collagen rich rosettes like this but it has a much more prominent round cell appearance around the edge of the rim of the nodules are very like small round blue cell almost",
"med_umls_ids": "[[{'entity': 'Unique', 'concept_id': 'C1710548', 'confidence': 1.0}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'hyalinization', 'concept_id': 'C0333438', 'confidence': 1.0}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'vessels', 'concept_id': 'C0005847', 'confidence': 1.0}], [{'entity': 'Neuroblastoma-like variant', 'concept_id': 'C1419295', 'confidence': 0.6672105193138123}, {'entity': 'schwannoma', 'concept_id': 'C0027809', 'confidence': 0.9999998807907104}, {'entity': 'differential', 'concept_id': 'C0443199', 'confidence': 1.0}, {'entity': 'round cell', 'concept_id': 'C0487470', 'confidence': 1.0}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'edge', 'concept_id': 'C0205154', 'confidence': 1.0}, {'entity': 'nodules', 'concept_id': 'C0028259', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_635",
"caption_rating": "8"
},
{
"": "1008596",
"caption": "Identification of a classic DFSP with a storiform pattern and a ring chromosome, collagen A, platelet-derived growth factor, and translocation.",
"image_path": "LlPaENuqzVQ_image_823fcef0-798a-483a-ac1c-6b76d266e446.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['Storiform pattern', 'Ring chromosome', 'Collagen A', 'Platelet-derived growth factor', 'Soft tissue neoplasm']",
"noisy_text": " you do have the nice, beautiful storiform pattern here. And you don't really need a CD34 stain here. You can do it if you want to, if you like to sort of charge patients extra money, but this is a classic DFSB. And that ring chromosome, the collagen A, platelet-derived growth factor, the translocation is classic for that. And one other thing, if you biopsy the surface of DFSB, sometimes it can look like a neurofibroma. So beware of taking superficial shave biopsies of DFSBs. You need to take a deep incisional biopsy. Whenever you're dealing with a soft tissue neoplasm and dermatology, get out the knife and fork. Don't get the punch biopsy out. Don't ever do a shave on it. So you got to take a real biopsy when you're dealing with a soft tissue neoplasm because of",
"corrected_text": " you do have the nice, beautiful storiform pattern here. And you don't really need a CD34 stain here. You can do it if you want to, if you like to sort of charge patients extra money, but this is a classic DFSP. And that ring chromosome, the collagen A, platelet-derived growth factor, the translocation is classic for that. And one other thing, if you biopsy the surface of DFSP, sometimes it can look like a neurofibroma. So beware of taking superficial shave biopsies of DFSBs. You need to take a deep incisional biopsy. Whenever you're dealing with a soft tissue neoplasm and dermatology, get out the knife and fork. Don't get the punch biopsy out. Don't ever do a shave on it. So you got to take a real biopsy when you're dealing with a soft tissue neoplasm because of",
"med_umls_ids": "[[{'entity': 'Identification', 'concept_id': 'C0020792', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}, {'entity': 'storiform pattern', 'concept_id': 'C1336510', 'confidence': 0.8142904043197632}, {'entity': 'ring chromosome', 'concept_id': 'C0035639', 'confidence': 1.0}, {'entity': 'collagen A', 'concept_id': 'C0009325', 'confidence': 0.9128584265708923}, {'entity': 'platelet-derived growth factor', 'concept_id': 'C0032200', 'confidence': 1.0}, {'entity': 'translocation', 'concept_id': 'C0040715', 'confidence': 1.0}], [{'entity': 'Caution', 'concept_id': 'C1882442', 'confidence': 0.7039048671722412}, {'entity': 'superficial', 'concept_id': 'C0205124', 'confidence': 1.0}, {'entity': 'DFSPs', 'concept_id': 'C0334464', 'confidence': 0.8083938360214233}, {'entity': 'recommendation', 'concept_id': 'C0034866', 'confidence': 1.0}, {'entity': 'deep incisional biopsy', 'concept_id': 'C0184922', 'confidence': 0.8345454335212708}, {'entity': 'dealing', 'concept_id': 'C0556449', 'confidence': 0.7019717693328857}, {'entity': 'soft tissue neoplasm', 'concept_id': 'C0037579', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_636",
"caption_rating": "8"
},
{
"": "1009256",
"caption": "Histopathological description of chronic colitis with activity and granulomas in the lamina propria.",
"image_path": "r7OA0Trj5hQ_image_3d654da7-aeca-49f7-83ba-b20d697619bd.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['cryptitis', 'cryptitis', 'crypt abscess', 'variation in size', 'granulomas in the lamina propria', 'variation in size']",
"noisy_text": " If it is esophagus, it is eosinophilic esophagitis, eosinophilic entritis, eosinophilic colitis. So eosinophilic gastroenteritis. Here it is a cryptitis and cryptopsis. And the glands are also pushed well apart. The glands are showing variation in size, shape, distribution. So this is chronic colitis with activity. These are granulomas in the lamina propria. Think of tuberculosis in India, sarcoidosis, fungal infections, or idiopathic, or foreign bodies. So those are all the four main things. Any granuloma, infectious or non-infectious. When infectious,",
"corrected_text": " If it is esophagus, it is eosinophilic esophagitis, eosinophilic enteritis, eosinophilic colitis. So eosinophilic gastroenteritis. Here it is a cryptitis and crypt abscess. And the glands are also pushed well apart. The glands are showing variation in size, shape, distribution. So this is chronic colitis with activity. These are granulomas in the lamina propria. Think of tuberculosis in India, sarcoidosis, fungal infections, or idiopathic, or foreign bodies. So those are all the four main things. Any granuloma, infectious or non-infectious. When infectious,",
"med_umls_ids": "[[{'entity': 'diagnoses', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'eosinophilic', 'concept_id': 'C0333930', 'confidence': 1.0}, {'entity': 'inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}, {'entity': 'esophagus', 'concept_id': 'C0014876', 'confidence': 1.0}, {'entity': 'enteritis', 'concept_id': 'C0014335', 'confidence': 1.0}, {'entity': 'colitis', 'concept_id': 'C0009319', 'confidence': 1.0}], [{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'chronic colitis', 'concept_id': 'C0267375', 'confidence': 0.9999999403953552}, {'entity': 'activity', 'concept_id': 'C0026606', 'confidence': 1.0}, {'entity': 'granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_637",
"caption_rating": "9"
},
{
"": "1006370",
"caption": "The key differential diagnosis is an acquired digital fibroma or an acquired digital fibrokeratoma.",
"image_path": "8S4LeiO6Bbk_image_0b555a52-b342-471e-b863-fcfab968abaa.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['nerve fascicles', 'spindle-shaped cells', 'rudimentary supernumerary digit', 'ulnar aspect of the fifth digit', 'acquired digital fibroma', 'acquired digital fibrokeratoma', 'trichilemmal cyst']",
"noisy_text": " core here we've got several well-defined nerve fascicles and the spindled cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions of course tend to occur along the ulnar eye aspect of the fifth digit. They're not infrequently bilateral and the key differential here of course is an acquired digital fibroma or an acquired digital fibrocarotoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if",
"corrected_text": " core here we've got several well-defined nerve fascicles and the spindle cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions of course tend to occur along the ulnar eye aspect of the fifth digit. They're not infrequently bilateral and the key differential here of course is an acquired digital fibroma or an acquired digital fibrokeratoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if",
"med_umls_ids": "[[{'entity': 'Well-defined nerve fascicles', 'concept_id': 'C1185741', 'confidence': 0.5682494640350342}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'S100', 'concept_id': 'C3273837', 'confidence': 1.0}, {'entity': 'SOX10', 'concept_id': 'C1420317', 'confidence': 0.9999998807907104}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'rudimentary supernumerary digit', 'concept_id': 'C0152427', 'confidence': 0.8142021894454956}], [{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'ulnar', 'concept_id': 'C0442044', 'confidence': 1.0}, {'entity': 'aspect', 'concept_id': 'C1547011', 'confidence': 1.0}, {'entity': 'fifth digit', 'concept_id': 'C0230403', 'confidence': 0.912693440914154}, {'entity': 'bilateral', 'concept_id': 'C0238767', 'confidence': 1.0}], [{'entity': 'differential diagnosis', 'concept_id': 'C0011906', 'confidence': 1.0}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}, {'entity': 'digital fibroma', 'concept_id': 'C4538745', 'confidence': 0.8997364640235901}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}], [{'entity': 'Trichilemmal cyst', 'concept_id': 'C2266788', 'confidence': 1.0}, {'entity': 'biopsy specimen', 'concept_id': 'C0677862', 'confidence': 1.0}, {'entity': 'slide number', 'concept_id': 'C3828004', 'confidence': 0.8261933326721191}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_638",
"caption_rating": "8"
},
{
"": "1006269",
"caption": "Intercommunicating slit-like vascular spaces in the mass.",
"image_path": "PJX3uZ7fRn4_image_6e06942c-9cdd-4403-a87b-fb8b5258284b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gynecologic', 'Soft tissue', 'Hematopathology']",
"roi_text": "['vascular channels', 'chorionic villi', 'calcification', 'vascular channels', 'chorionic villi', 'calcification']",
"noisy_text": " This is a section from placenta which shows a large irregular area with proliferation of thin walled vascular channels of variable size towards the fetal surface of placenta. Smaller chorionic villi can be seen towards the maternal site. Higher magnification of the same showing large vascular channels in the chorion filled with blood. Still higher magnification showing intercommunicating slit-like vascular spaces in the mass. Focal area of calcification can be seen in the tumor. Still another area",
"corrected_text": " This is a section from placenta which shows a large irregular area with proliferation of thin walled vascular channels of variable size towards the fetal surface of placenta. smaller chorionic villi are not incorrect can be seen towards the maternal site. Higher magnification of the same showing large vascular channels in the chorion filled with blood. Still higher magnification showing intercommunicating slit-like vascular spaces in the mass. Focal area of calcification can be seen in the tumor. Still another area",
"med_umls_ids": "[[{'entity': 'Proliferation', 'concept_id': 'C0334094', 'confidence': 1.0}, {'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}, {'entity': 'variable size', 'concept_id': 'C1866144', 'confidence': 0.8559831976890564}, {'entity': 'fetal', 'concept_id': 'C0015965', 'confidence': 1.0}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'placenta', 'concept_id': 'C0032043', 'confidence': 1.0}], [{'entity': 'chorionic villi', 'concept_id': 'C0008508', 'confidence': 1.0}, {'entity': 'maternal site', 'concept_id': 'C0026591', 'confidence': 0.7640593647956848}], [{'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}, {'entity': 'chorion', 'concept_id': 'C0008503', 'confidence': 0.9999998807907104}, {'entity': 'blood', 'concept_id': 'C0005767', 'confidence': 1.0}], [{'entity': 'Intercommunicating', 'concept_id': 'C0205196', 'confidence': 0.8271207213401794}, {'entity': 'vascular spaces', 'concept_id': 'C0225983', 'confidence': 0.819495439529419}, {'entity': 'mass', 'concept_id': 'C0577559', 'confidence': 1.0}], [{'entity': 'Focal area', 'concept_id': 'C0205234', 'confidence': 0.7634891271591187}, {'entity': 'calcification', 'concept_id': 'C0006660', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_639",
"caption_rating": "7"
},
{
"": "1004287",
"caption": "Histopathological description of a specimen with banal appearing melanocytes present within the dermis.",
"image_path": "8S4LeiO6Bbk_image_4e20fd6c-5a2b-4179-a0e8-65900ee18335.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['dermis', 'round oval nuclei', 'cytoplasm', 'dermis', 'sclerotic stroma', 'melanocytes', 'melanophages', 'dendritic', 'spindle-shaped']",
"noisy_text": " appearance, a round oval nuclei and a moderate amount of cytoplasm. And then we have nest cords and strands of otherwise banal appearing or banal appearing melanocytes present within the underlying dermis. There is evidence of maturation with depth in these sections, and no mitotic pairs. In the central portion of the specimen, you can see that the dermis is a little more sclerotic. And we've got the presence of separately heavily pigmented melanovagias. And then if we look at our top piece of tissue, again, we have the more banal appearing melanocytes out of the periphery. And centrally, we've got embedded within a sclerotic stroma a second distinct morphologic population of melanocytes. Some of these are dendritic, others have spindled or fusiform-shaped",
"corrected_text": " appearance, a round oval nuclei and a moderate amount of cytoplasm. And then we have nest cords and strands of otherwise banal appearing or banal appearing melanocytes present within the underlying dermis. There is evidence of maturation with depth in these sections, and no mitotic pairs. In the central portion of the specimen, you can see that the dermis is a little more sclerotic. And we've got the presence of separately heavily pigmented melanovagias. And then if we look at our top piece of tissue, again, we have the more banal appearing melanocytes out of the periphery. And centrally, we've got embedded within a sclerotic stroma a second distinct morphologic population of melanocytes. Some of these are dendritic, others have spindle-shaped or fusiform-shaped",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'specimen', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'banal', 'concept_id': 'C0004722', 'confidence': 0.7279530763626099}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}], [{'entity': 'Evidence', 'concept_id': 'C3887511', 'confidence': 1.0}, {'entity': 'maturation', 'concept_id': 'C0678723', 'confidence': 1.0}, {'entity': 'depth', 'concept_id': 'C0205125', 'confidence': 1.0}, {'entity': 'mitotic', 'concept_id': 'C1513354', 'confidence': 1.0}, {'entity': 'pairs', 'concept_id': 'C0600436', 'confidence': 0.8094210028648376}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'heavily', 'concept_id': 'C0337678', 'confidence': 0.6902515292167664}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'melanophages', 'concept_id': 'C3280463', 'confidence': 0.9375340938568115}], [{'entity': 'Sclerotic', 'concept_id': 'C0036429', 'confidence': 0.9999999403953552}, {'entity': 'stroma', 'concept_id': 'C0927195', 'confidence': 1.0}, {'entity': 'morphologic population', 'concept_id': 'C0543482', 'confidence': 0.699425995349884}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_640",
"caption_rating": "8"
},
{
"": "1007136",
"caption": "Description of a low-grade fibromyxoid sarcoma with sclerotic areas and variability in cellularity.",
"image_path": "QDb68_G1HR4_image_fe93b661-03d4-4bcb-8518-c7b5f0869011.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Sclerotic areas', 'cellular zone', 'hypocellular sclerotic collagen rich zone']",
"noisy_text": " So again I'm just and oh this is a good example too of how you can have those sclerotic zones that are look at the transition there from really quite cellular in this case much more cellular than usual transitioning into sclerotic zone that you might if you weren't familiar with this tumor you might actually not even recognize that this is really part of the tumor but it is look at this area here these are tumor cells mingling in to just a very hypocellular sclerotic collagen rich zone in this example of low-grade fibromyxoid sarcoma. So this is I think a really good one from low power to see the variability in the cellularity and in",
"corrected_text": " So again I'm just and oh this is a good example too of how you can have those sclerotic zones that are look at the transition there from really quite cellular in this case much more cellular than usual transitioning into sclerotic zone that you might if you weren't familiar with this tumor you might actually not even recognize that this is really part of the tumor but it is look at this area here these are tumor cells mingling in to just a very hypocellular sclerotic collagen rich zone in this example of low-grade fibromyxoid sarcoma. So this is I think a really good one from low power to see the variability in the cellularity and in",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'sclerotic', 'concept_id': 'C0036429', 'confidence': 0.9999999403953552}, {'entity': 'areas', 'concept_id': 'C0205146', 'confidence': 1.0}, {'entity': 'variability', 'concept_id': 'C2827666', 'confidence': 0.9999998807907104}, {'entity': 'cellularity', 'concept_id': 'C0178539', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_641",
"caption_rating": "8"
},
{
"": "1007245",
"caption": "Perineurioma can be difficult to diagnose because it overlaps with low-grade fibromyxoid sarcoma histologically and on immunohistochemistry.",
"image_path": "QDb68_G1HR4_image_7807ddd7-4e7e-4a1d-aeba-2e2b021c55bc.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Deep soft tissue', 'Perineurioma', 'Low-grade fibromyxoid sarcoma', 'Immunohistochemistry', 'Swirling growth']",
"noisy_text": " involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is more of a difficult problem because perineurioma has a lot of overlap histologically with low-grade fibromyxoid sarcoma and also immunohistochemically. On immunostains, EMA, Clodin-1 and Glut-1 are three immunostains that will usually stain perineuriomas. The problem is that low-grade fibromyxoid sarcomas often express at least focal EMA, so that's a problem and additionally, the examples of low-grade fibromyxoid sarcoma that have dramatic swirling and whirling growth, those are the ones that have a perineurioma like pattern, the ones that mimic perineurioma. They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The",
"corrected_text": " involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is more of a difficult problem because perineurioma has a lot of overlap histologically with low-grade fibromyxoid sarcoma and also immunohistochemically. On immunostains, EMA, Clodin-1 and Glut-1 are three immunostains that will usually stain perineuriomas. The problem is that low-grade fibromyxoid sarcomas often express at least focal EMA, so that's a problem and additionally, the examples of low-grade fibromyxoid sarcoma that have dramatic swirling and whirling growth, those are the ones that have a perineurioma like pattern, the ones that mimic perineurioma. They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The",
"med_umls_ids": "[[{'entity': 'CD34', 'concept_id': 'C0054953', 'confidence': 1.0}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'deep soft tissue tumors', 'concept_id': 'C0037579', 'confidence': 0.8622524738311768}], [{'entity': 'Perineurioma', 'concept_id': 'C0751691', 'confidence': 0.9999999403953552}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'histologically', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'immunohistochemistry', 'concept_id': 'C0021044', 'confidence': 0.9999998807907104}], [{'entity': 'EMA', 'concept_id': 'C0268596', 'confidence': 0.9999999403953552}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}, {'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'immunohistochemical stains', 'concept_id': 'C4317108', 'confidence': 0.9999999403953552}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibrosarcomas', 'concept_id': 'C0016057', 'confidence': 1.0}, {'entity': 'EMA', 'concept_id': 'C0268596', 'confidence': 0.9999999403953552}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}], [{'entity': 'Low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'swirling', 'concept_id': 'C0233591', 'confidence': 0.7064549922943115}, {'entity': 'growth', 'concept_id': 'C0018270', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'express', 'concept_id': 'C0017262', 'confidence': 0.8176293969154358}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}], [{'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'reports', 'concept_id': 'C0684224', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcomas', 'concept_id': 'C1275282', 'confidence': 0.8123146891593933}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_642",
"caption_rating": "9"
},
{
"": "1008436",
"caption": "Prognosis is worse for patients with high-grade round cell morphology.",
"image_path": "pBR26SS0FX8_image_decfa00c-795e-44d0-9da3-0464679a982a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Hematopathology', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " and not other parts of pathology where you have to calculate percent of key 67 staining and stuff. So anyway, I don't know if that's a good answer, but it's an honest one. Yeah, so the question brought up is that post treatment, once these tumors have been radiated, they usually, the vast majority of them just completely get wiped out. And all that's left is sclerotic collagen, a little bit of the vascular branchy stuff and mature adipocytes with occasional little tiny lipoblasts, maybe a few pockets of myxoid change. And if there was a round cell component, you'll never know because it usually gets wiped out and blasted by the radiation. So I agree, that's the problem. The trade-off is that doing the needle ahead of time to get the diagnosis on a needle biopsy allows you to make a diagnosis and pre-treat the tumor. The trade-off though, is that on the excision specimen, you'll really never probably know what the original morphology was like. And I feel like this is one of the trade-offs we've made in modern medicine, where there are benefits of having a needle biopsy before excision, a lot of benefits and probably more benefits than risks, but there are some downsides. And that's one of them is pre-treatment, wipes out the original morphology. But again, it's the main difference is the prognosis. The long-term prognosis is worse, unfortunately, for patients that have high-grade round cell morphology. And even though the low-grade myxoid liposarcoma, in the past, there was a thought that like, 90% of the patients were gonna be okay and 10% would get METs. But I think with longer follow-up, we started to see that a significantly larger number actually even of people with low-grade conventional myxoid liposarcoma will get metastases. I think the WHO says, I think their current quote is between 30 and it's more than 30%, I think. And different studies show different things so that even sometimes it's longer and farther out. Oh yeah, I forgot to mention, the other weird thing that you should know about myxoid liposarcoma, like all sarcomas, it will metastasize the lungs oftentimes. But it",
"corrected_text": " and not other parts of pathology where you have to calculate percent of key 67 staining and stuff. So anyway, I don't know if that's a good answer, but it's an honest one. Yeah, so the question brought up is that post treatment, once these tumors have been radiated, they usually, the vast majority of them just completely get wiped out. And all that's left is sclerotic collagen, a little bit of the vascular branching and mature adipocytes with occasional little tiny lipoblasts, maybe a few pockets of myxoid change. And if there was a round cell component, you'll never know because it usually gets wiped out and blasted by the radiation. So I agree, that's the problem. The trade-off is that doing the needle ahead of time to get the diagnosis on a needle biopsy allows you to make a diagnosis and pre-treat the tumor. The trade-off though, is that on the excision specimen, you'll really never probably know what the original morphology was like. And I feel like this is one of the trade-offs we've made in modern medicine, where there are benefits of having a needle biopsy before excision, a lot of benefits and probably more benefits than risks, but there are some downsides. And that's one of them is pre-treatment, wipes out the original morphology. But again, it's the main difference is the prognosis. The long-term prognosis is worse, unfortunately, for patients that have high-grade round cell morphology. And even though the low-grade myxoid liposarcoma, in the past, there was a thought that like, 90% of the patients were gonna be okay and 10% would get METs. But I think with longer follow-up, we started to see that a significantly larger number actually even of people with low-grade conventional myxoid liposarcoma will get metastases. I think the WHO says, I think their current quote is between 30 and it's more than 30%, I think. And different studies show different things so that even sometimes it's longer and farther out. Oh yeah, I forgot to mention, the other weird thing that you should know about myxoid liposarcoma, like all sarcomas, it will metastasize the lungs oftentimes. But it",
"med_umls_ids": "[[{'entity': 'Radiation treatment', 'concept_id': 'C1522449', 'confidence': 0.9999999403953552}, {'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'sclerotic', 'concept_id': 'C0036429', 'confidence': 0.9999999403953552}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'vascular branching', 'concept_id': 'C0005847', 'confidence': 0.7225151658058167}, {'entity': 'mature', 'concept_id': 'C0205286', 'confidence': 1.0}, {'entity': 'adipocytes', 'concept_id': 'C0206131', 'confidence': 1.0}, {'entity': 'lipoblasts', 'concept_id': 'C0225323', 'confidence': 0.8551441431045532}, {'entity': 'myxoid change', 'concept_id': 'C0205295', 'confidence': 0.815497636795044}], [{'entity': 'Needle biopsy', 'concept_id': 'C0005560', 'confidence': 1.0}, {'entity': 'excision', 'concept_id': 'C0015252', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'pre-treatment', 'concept_id': 'C0419819', 'confidence': 0.7933163046836853}, {'entity': 'original', 'concept_id': 'C0205313', 'confidence': 1.0}, {'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}], [{'entity': 'Prognosis', 'concept_id': 'C0033325', 'confidence': 1.0}, {'entity': 'patients', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'high-grade round cell', 'concept_id': 'C1512433', 'confidence': 0.7649602890014648}, {'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}], [{'entity': 'Low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'myxoid liposarcoma', 'concept_id': 'C0206634', 'confidence': 1.0}, {'entity': 'metastasize', 'concept_id': 'C0027627', 'confidence': 1.0}], [{'entity': 'Myxoid liposarcoma', 'concept_id': 'C0206634', 'confidence': 1.0}, {'entity': 'metastasize', 'concept_id': 'C0027627', 'confidence': 1.0}, {'entity': 'lungs', 'concept_id': 'C0024109', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_643",
"caption_rating": "8"
},
{
"": "1008573",
"caption": "Surgical resection of solitary metastases from the lung may prolong the disease course.",
"image_path": "QDb68_G1HR4_image_1ee54613-6bec-4dbb-9e02-7d53f141620e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Metastasis to the lung or pleura']",
"noisy_text": " diagnosis when a metastasis finally shows up. So unfortunately, that's a frustrating thing I think for both the treating physicians and the patients to know that basically you're never totally in the clear these things can recur or metastasize very, very long after diagnosis. When they metastasize, they often go to the lung or the pleura and there probably is some benefit at least in the opinion of some of the people that I know who treat these sarcomas in removing solitary metastases from the lung if they're surgically amenable to surgical resection that you can remove the metastasis and then the patient may go quite a few more years before having another metastasis. So you can really kind of prolong the disease course by removing metastasis. Obviously if you're a patient watching this that has this tumor, please make sure you see an expert",
"corrected_text": " diagnosis when a metastasis finally shows up. So unfortunately, that's a frustrating thing I think for both the treating physicians and the patients to know that basically you're never totally in the clear these things can recur or metastasize very, very long after diagnosis. When they metastasize, they often go to the lung or the pleura and there probably is some benefit at least in the opinion of some of the people that I know who treat these sarcomas in removing solitary metastases from the lung if they're surgically amenable to surgical resection that you can remove the metastasis and then the patient may go quite a few more years before having another metastasis. So you can really kind of prolong the disease course by removing metastasis. Obviously if you're a patient watching this that has this tumor, please make sure you see an expert",
"med_umls_ids": "[[{'entity': 'Metastasis', 'concept_id': 'C0027627', 'confidence': 1.0}, {'entity': 'metastasize', 'concept_id': 'C0027627', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'lung', 'concept_id': 'C0024109', 'confidence': 1.0}, {'entity': 'pleura', 'concept_id': 'C0032225', 'confidence': 1.0}], [{'entity': 'Surgical resection', 'concept_id': 'C0015252', 'confidence': 1.0}, {'entity': 'solitary metastases', 'concept_id': 'C0027627', 'confidence': 0.7712292075157166}, {'entity': 'lung', 'concept_id': 'C0024109', 'confidence': 1.0}, {'entity': 'disease course', 'concept_id': 'C0242656', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_644",
"caption_rating": "7"
},
{
"": "1005819",
"caption": "Well-defined nerve fascicles with spindle-shaped cells, which are positive with S100 and SOX10, defining the diagnosis of rudimentary supernumerary digit.",
"image_path": "8S4LeiO6Bbk_image_05eec250-fd22-4ed8-93df-a011dc2c30f2.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['nerve fascicles', 'spindle-shaped cells', 'rudimentary supernumerary digit', 'ulnar aspect of the fifth digit', 'acquired digital fibroma', 'acquired digital fibrokeratoma', 'trichilemmal cyst', 'nerve fascicles', 'spindle-shaped cells', 'rudimentary supernumerary digit', 'ulnar aspect of the fifth digit', 'acquired digital fibroma', 'acquired digital fibrokeratoma', 'trichilemmal cyst', 'nerve fascicles', 'spindle-shaped cells', 'rudimentary supernumerary digit', 'ulnar aspect of the fifth digit', 'acquired digital fibroma', 'acquired digital fibrokeratoma', 'trichilemmal cyst']",
"noisy_text": " core here we've got several well-defined nerve fascicles and the spindled cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions of course tend to occur along the ulnar eye aspect of the fifth digit. They're not infrequently bilateral and the key differential here of course is an acquired digital fibroma or an acquired digital fibrocarotoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if",
"corrected_text": " core here we've got several well-defined nerve fascicles and the spindle cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions of course tend to occur along the ulnar eye aspect of the fifth digit. They're not infrequently bilateral and the key differential here of course is an acquired digital fibroma or an acquired digital fibrokeratoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if",
"med_umls_ids": "[[{'entity': 'Well-defined nerve fascicles', 'concept_id': 'C1185741', 'confidence': 0.5682494640350342}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'S100', 'concept_id': 'C3273837', 'confidence': 1.0}, {'entity': 'SOX10', 'concept_id': 'C1420317', 'confidence': 0.9999998807907104}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'rudimentary supernumerary digit', 'concept_id': 'C0152427', 'confidence': 0.8142021894454956}], [{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'ulnar', 'concept_id': 'C0442044', 'confidence': 1.0}, {'entity': 'aspect', 'concept_id': 'C1547011', 'confidence': 1.0}, {'entity': 'fifth digit', 'concept_id': 'C0230403', 'confidence': 0.912693440914154}, {'entity': 'bilateral', 'concept_id': 'C0238767', 'confidence': 1.0}], [{'entity': 'differential diagnosis', 'concept_id': 'C0011906', 'confidence': 1.0}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}, {'entity': 'digital fibroma', 'concept_id': 'C4538745', 'confidence': 0.8997364640235901}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}], [{'entity': 'Trichilemmal cyst', 'concept_id': 'C2266788', 'confidence': 1.0}, {'entity': 'biopsy specimen', 'concept_id': 'C0677862', 'confidence': 1.0}, {'entity': 'slide number', 'concept_id': 'C3828004', 'confidence': 0.8261933326721191}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_645",
"caption_rating": "9"
},
{
"": "1007998",
"caption": "Foreign bodies can also cause sarcoid reactions.",
"image_path": "udoW6VSqsm4_image_f4ffefb9-a3d1-477d-bc3c-a77762f8b106.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['involvement around nerves', 'sarcoid granulomatous inflammation', 'foreign bodies', 'involvement around nerves', 'sarcoid granulomatous inflammation', 'foreign bodies']",
"noisy_text": " Can I ask a quick question about the sarcoid with the two... The nansins? So, I had a case, I saw a case that looked kind of horizontal, but it was sarcoid. And so, what other ways can you tell? Sometimes it can be difficult, but usually you're going to see involvement around nerves damaged nerves. You're about to get sarcoidal granulomatous inflammation. They always have very high risk inflammatory reactions. They just wipe out the nerves. So, that's helpful. Wasn't it here that we, not long ago, we saw a sarcoidal reaction for a foreign body? Yeah, there are several foreign bodies that can do it. Silica can",
"corrected_text": " Can I ask a quick question about the sarcoid with the two... The non-caseating? So, I had a case, I saw a case that looked kind of horizontal, but it was sarcoid. And so, what other ways can you tell? Sometimes it can be difficult, but usually you're going to see involvement around nerves damaged nerves. You're about to get sarcoid granulomatous inflammation. They always have very high risk inflammatory reactions. They just wipe out the nerves. So, that's helpful. Wasn't it here that we, not long ago, we saw a sarcoid reaction for a foreign body? Yeah, there are several foreign bodies that can do it. Silica can",
"med_umls_ids": "[[{'entity': 'Sarcoid', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'granulomatous inflammation', 'concept_id': 'C0553697', 'confidence': 1.0}, {'entity': 'damaged', 'concept_id': 'C1881662', 'confidence': 0.8042823076248169}, {'entity': 'nerves', 'concept_id': 'C0027740', 'confidence': 1.0}, {'entity': 'high-risk', 'concept_id': 'C0556482', 'confidence': 0.9005044102668762}, {'entity': 'inflammatory reactions', 'concept_id': 'C0021368', 'confidence': 0.9414709806442261}], [{'entity': 'Foreign bodies', 'concept_id': 'C0016542', 'confidence': 1.0}, {'entity': 'sarcoid', 'concept_id': 'C0036202', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_646",
"caption_rating": "7"
},
{
"": "1008802",
"caption": "The tissue has myxoid features with very fine delicate collagen.",
"image_path": "QDb68_G1HR4_image_8184162a-6f50-40b1-bc14-9c1f1ddf7962.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['myxoid features', 'fine delicate collagen', 'cellular intramuscular myxoma', 'fibrous areas', 'cellular areas', 'MUC4 stain']",
"noisy_text": " Here's again the myxoid background I really think this is very helpful. The very very fine delicate collagen that you see. Now areas like this I think can kind of resemble what you see in a so-called cellular intramuscular myxoma. Intramuscular myxomas are usually very blue and myxoid very hypocellular but sometimes they get more fibrous and more cellular areas. And on a needle biopsy I think that can be challenging. So I think usually with some experience you can tell them apart on H and E most of the time but when I have any doubt I just do a MUC4 stain. The MUC4 is negative and on a needle it looks like a myxoma with some kind of fibrous or a little bit more cellular areas and then I just say that it's probably a cellular intramuscular myxoma. So I think MUC4",
"corrected_text": " Here's again the myxoid background I really think this is very helpful. The very very fine delicate collagen that you see. Now areas like this I think can kind of resemble what you see in a so-called cellular intramuscular myxoma. Intramuscular myxomas are usually very blue and myxoid very hypocellular but sometimes they get more fibrous and more cellular areas. And on a needle biopsy I think that can be challenging. So I think usually with some experience you can tell them apart on H and E most of the time but when I have any doubt I just do a MUC4 stain. The MUC4 is negative and on a needle it looks like a myxoma with some kind of fibrous or a little bit more cellular areas and then I just say that it's probably a cellular intramuscular myxoma. So I think MUC4",
"med_umls_ids": "[[{'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'myxoid', 'concept_id': 'C0205295', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}], [{'entity': 'narrator', 'concept_id': 'C1135957', 'confidence': 0.7711340188980103}, {'entity': 'cellular', 'concept_id': 'C0007634', 'confidence': 0.9999999403953552}, {'entity': 'intramuscular', 'concept_id': 'C0442117', 'confidence': 1.0}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}, {'entity': 'cellular areas', 'concept_id': 'C0007634', 'confidence': 0.7882957458496094}], [{'entity': 'MUC4', 'concept_id': 'C1417496', 'confidence': 0.9999999403953552}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'confirm', 'concept_id': 'C0521093', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'cellular intramuscular myxoma', 'concept_id': 'C1334260', 'confidence': 0.8910117149353027}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_647",
"caption_rating": "8"
},
{
"": "1005892",
"caption": "Differential diagnosis includes basal cell carcinoma with sebaceous differentiation and sebaceoma.",
"image_path": "udoW6VSqsm4_image_dc97fc88-1339-4708-a31f-d20e7045a8bc.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " So these are items in the differential diagnosis. Basal cell with sebaceous differentiation, if you're going to make that diagnosis, it generally needs to look like a basal cell with nice clefting and put the palisade in there and all that, and then have foci where there's obvious sebaceous differentiation. You'll see that on occasion. But I would probably call this sebaceoma, without thinking it's sort of synonymous with sebaceous epithelium. Now, is there any condition you have to worry about with these? With any sebaceous neoplasm, I guess you have to have meritoria in the back of your mind, but I don't know if you really need to worry about it. There's a lot of debate on just kind of using your clinical acumen as far as staining, if you guys don't stain every single sebaceous neoplasm. Yeah, and that's generally true, but if",
"corrected_text": " So these are items in the differential diagnosis. Basal cell with sebaceous differentiation, if you're going to make that diagnosis, it generally needs to look like a basal cell with nice clefting and put the palisade in there and all that, and then have foci where there's obvious sebaceous differentiation. You'll see that on occasion. But I would probably call this sebaceoma, without thinking it's sort of synonymous with sebaceous epithelium. Now, is there any condition you have to worry about with these? With any sebaceous neoplasm, I guess you have to have meritoria in the back of your mind, but I don't know if you really need to worry about it. There's a lot of debate on just kind of using your clinical acumen as far as staining, if you guys don't stain every single sebaceous neoplasm. Yeah, and that's generally true, but if",
"med_umls_ids": "[[{'entity': 'Differential diagnosis', 'concept_id': 'C0011906', 'confidence': 1.0}, {'entity': 'basal cell carcinoma', 'concept_id': 'C0007117', 'confidence': 1.0}, {'entity': 'sebaceous differentiation', 'concept_id': 'C1882988', 'confidence': 1.0}, {'entity': 'sebaceoma', 'concept_id': 'C1275210', 'confidence': 1.0}], [{'entity': 'Sebaceous neoplasms', 'concept_id': 'C0036503', 'confidence': 0.9154399633407593}, {'entity': 'associated with', 'concept_id': 'C0332281', 'confidence': 1.0}, {'entity': 'meritoria', 'concept_id': 'C1057424', 'confidence': 0.6892908811569214}], [{'entity': 'Clinical acumen', 'concept_id': 'C1828480', 'confidence': 0.7179506421089172}, {'entity': 'staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'sebaceous neoplasms', 'concept_id': 'C0036503', 'confidence': 0.9154399633407593}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_648",
"caption_rating": "8"
},
{
"": "1006218",
"caption": "Description of fibromyxoid stroma and diffuse dissection throughout the dermis.",
"image_path": "LlPaENuqzVQ_image_e65482d5-11ca-44e7-a128-fd8c780345dd.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['Eosinophilic cells with squamous morphology', 'Fibromyxoid stroma', 'Diffuse dissection throughout the dermis']",
"noisy_text": " We have a diagnosis called the surface of the sclerosing epithelial neoplasm. You have to go back and take more, another biopsy. MACs often will have a little more squamoid morphology like this. Can you see those kind of eosinophilic cells? They kind of look a little bit more like squamous cells a little bit. So that favors MAC more than like a desmoplastic tricho or even like a serendoma. A serendoma usually also is obviously much smaller. You can't take a shave biopsy and get an entire serendoma out. And usually the stroma is more prominent in the serendoma. Notice that this stroma is more fibromucinous. So this thing is kind of dissecting diffusely throughout the dermis here. I don't see",
"corrected_text": " We have a diagnosis called the surface of the sclerosing epithelial neoplasm. You have to go back and take more, another biopsy. MACs often will have a little more squamous morphology like this. Can you see those kind of eosinophilic cells? They kind of look a little bit more like squamous cells a little bit. So that favors MAC more than like a desmoplastic tricholemmoma or even like a syringoma. A syringoma usually also is obviously much smaller. You can't take a shave biopsy and get an entire syringoma out. And usually the stroma is more prominent in the syringoma. Notice that this stroma is more fibromyxoid. So this thing is kind of dissecting diffusely throughout the dermis here. I don't see",
"med_umls_ids": "[[{'entity': 'Diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'sclerosing', 'concept_id': 'C0036426', 'confidence': 0.833010733127594}, {'entity': 'epithelial neoplasm', 'concept_id': 'C1368683', 'confidence': 1.0}, {'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}], [{'entity': 'Comparison', 'concept_id': 'C1707455', 'confidence': 1.0}, {'entity': 'squamous', 'concept_id': 'C1182670', 'confidence': 0.9999998807907104}, {'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}, {'entity': 'MAC', 'concept_id': 'C0009545', 'confidence': 0.9999999403953552}, {'entity': 'desmoplastic tricholemmoma', 'concept_id': 'C1275206', 'confidence': 0.9999999403953552}, {'entity': 'syringoma', 'concept_id': 'C0206673', 'confidence': 1.0}], [{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'fibromyxoid', 'concept_id': 'C0205766', 'confidence': 0.8987292051315308}, {'entity': 'stroma', 'concept_id': 'C0927195', 'confidence': 1.0}, {'entity': 'diffuse dissection', 'concept_id': 'C0205219', 'confidence': 0.7718934416770935}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_649",
"caption_rating": "8"
},
{
"": "1005331",
"caption": "KI67 can be used to distinguish basal cell hyperplasia from basal cell carcinoma.",
"image_path": "iklRyY1nBIE_image_881f5e73-0dd4-4feb-a638-26240b0dc364.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['basal cell hyperplasia', 'KI67 expression']",
"noisy_text": " fairly well circumscribed, no increased mitotic activity. Because one of the things you can do to distinguish if you're not sure is a KI67. KI67 will be very low in basal cell hyperplasia. Even fluorid basal cell hyperplasia should not have a very high KI67 expression. In contrast, basal cell carcinoma, as no surprise, is actually with a high KI67 level. So that's something else. In cases in which one is struggling, that's something that may be helpful. Let me see. Yeah, this is just another example of basal cell hyperplasia. This is in a Terp specimen. So it's not uncommon to",
"corrected_text": " fairly well circumscribed, no increased mitotic activity. Because one of the things you can do to distinguish if you're not sure is a KI67. KI67 will be very low in basal cell hyperplasia. Even fluorid basal cell hyperplasia should not have a very high KI67 expression. In contrast, basal cell carcinoma, as no surprise, is actually with a high KI67 level. So that's something else. In cases in which one is struggling, that's something that may be helpful. Let me see. Yeah, this is just another example of basal cell hyperplasia. This is in a Terp specimen. So it's not uncommon to",
"med_umls_ids": "[[{'entity': 'Fairly', 'concept_id': 'C4086298', 'confidence': 0.9045276641845703}, {'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'mitotic activity', 'concept_id': 'C1334779', 'confidence': 1.0}], [{'entity': 'KI67', 'concept_id': 'C1334508', 'confidence': 1.0}, {'entity': 'basal cell', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'basal cell carcinoma', 'concept_id': 'C0007117', 'confidence': 1.0}], [{'entity': 'Basal cell hyperplasia', 'concept_id': 'C0333990', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_650",
"caption_rating": "8"
},
{
"": "1007621",
"caption": "Presence of H. pylori in the luminal area or lumen of the stomach.",
"image_path": "r7OA0Trj5hQ_image_18a785c8-9d4e-4bed-8ce4-7bfac5084f2c.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Neutrophils on the epithelium indicating active inflammation', 'H. pylori in the luminal area or lumen', 'Goblet cells in the surface epithelium.']",
"noisy_text": " this is equivalent to cryptitis in the colon. In the stomach, we call it pit, so I don't want to call it pititis. It doesn't sound very great, but you can see the neutrophils sitting on the epithelium. So this is an active inflammation. Here, now we are coming to cytology. You see in the intra-luminal area or in the lumen, you see a lot of comma-shaped rods sitting on the epithelium, not going into the epithelium. So these are all the H. pylori in the oil immersion. Here, the surface epithelium shows goblet cells, and these are all biopsies",
"corrected_text": " this is equivalent to cryptitis in the colon. In the stomach, we call it pit, so I don't want to call it pititis. It doesn't sound very great, but you can see the neutrophils sitting on the epithelium. So this is an active inflammation. Here, now we are coming to cytology. You see in the luminal area or in the lumen, you see a lot of comma-shaped rods sitting on the epithelium, not going into the epithelium. So these are all the H. pylori in the oil immersion. Here, the surface epithelium shows goblet cells, and these are all biopsies",
"med_umls_ids": "[[{'entity': 'Active inflammation', 'concept_id': 'C0333361', 'confidence': 1.0}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'H. pylori', 'concept_id': 'C0079488', 'confidence': 1.0}, {'entity': 'luminal area', 'concept_id': 'C0524462', 'confidence': 0.7778207659721375}, {'entity': 'lumen', 'concept_id': 'C0524461', 'confidence': 0.9999998807907104}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}], [{'entity': 'Surface epithelium', 'concept_id': 'C1182809', 'confidence': 1.0}, {'entity': 'goblet cells', 'concept_id': 'C0506994', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_651",
"caption_rating": "8"
},
{
"": "1008518",
"caption": "Subepidermal bullous lesion resembling bullous pemphigoid under the microscope, likely pemphigoid gestation in a pregnant woman.",
"image_path": "udoW6VSqsm4_image_5161d79a-4817-48f7-b587-ce9234422c5f.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['subepidermal bullous lesion', 'bullous pemphigoid', 'microscope', 'pregnant woman', 'immunofluorescence pattern', 'Ig', 'C3']",
"noisy_text": " So EBA, DH, PCT. You don't have to go through the entire... I'm just subepidermal. I'm just going through them. I don't know what's the... What if this is a 25-year-old pregnant woman? Oh, gestational. Yeah, pemphigoid gestation. And that's what this is in this case. It looks exactly like bullous pemphigoid under the microscope. You can't tell it apart. So always think of it. And what's the immunofluorescence pattern that we can see? So you would see Ig, not Ag? No Ig at all. No, okay, no. But what do you see? I'm not sure. Anybody know? C3. Linear complement",
"corrected_text": " So EBA, DH, PCT. You don't have to go through the entire... I'm just subepidermal. I'm just going through them. I don't know what's the... What if this is a 25-year-old pregnant woman? Oh, gestational. Yeah, pemphigoid gestation. And that's what this is in this case. It looks exactly like bullous pemphigoid under the microscope. You can't tell it apart. So always think of it. And what's the immunofluorescence pattern that we can see? So you would see Ig, not Ag? No Ig at all. No, okay, no. But what do you see? I'm not sure. Anybody know? C3. Linear complement",
"med_umls_ids": "[[{'entity': 'Subepidermal', 'concept_id': 'C0221935', 'confidence': 0.8599841594696045}, {'entity': 'bullous lesion', 'concept_id': 'C0005758', 'confidence': 1.0}, {'entity': 'bullous pemphigoid', 'concept_id': 'C0030805', 'confidence': 0.9999999403953552}, {'entity': 'microscope', 'concept_id': 'C0181839', 'confidence': 1.0}, {'entity': 'pemphigoid', 'concept_id': 'C0030805', 'confidence': 0.9999999403953552}, {'entity': 'gestation', 'concept_id': 'C0032961', 'confidence': 1.0}, {'entity': 'pregnant woman', 'concept_id': 'C0033011', 'confidence': 1.0}], [{'entity': 'Immunofluorescence pattern', 'concept_id': 'C0016318', 'confidence': 0.8741495609283447}, {'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'Ig', 'concept_id': 'C0021027', 'confidence': 1.0}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'C3', 'concept_id': 'C1305853', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_652",
"caption_rating": "8"
},
{
"": "1006195",
"caption": "The lesion is a localized, circumscribed area without granulomatous abnormalities or dyskeratotic keratinocytes, ruling out porokeratosis.",
"image_path": "udoW6VSqsm4_image_01babf43-1324-4979-a4e0-a40cd4bcf37d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['loss of the cornified layer', 'loss of the cornified layer']",
"noisy_text": " And so, the other things we kind of talked about are a bit differential, but next slide. Nothing else really will give you this kind of localized circumscribed area like this, so it's not poro. That would have a coronal lamella with granulocidal abnormalities and dyskeratonic keratinocytes. We don't see that here, so this is just a loss of the coronified layer. And there's one other condition where you kind of get, where are some other little clonal, you know, somatic mutations that you can get abnormalities in the epithelium that occur just in localized areas. That's not like loss of the coronified layer. We'll put a couple of other diseases where you see just local areas that are abnormal, and you get normal skin to the side. So, poro is one. We'll put",
"corrected_text": " And so, the other things we kind of talked about are a bit differential, but next slide. Nothing else really will give you this kind of localized circumscribed area like this, so it's not poro. That would have a coronal lamella with granulomatous abnormalities and dyskeratotic keratinocytes. We don't see that here, so this is just a loss of the cornified layer. And there's one other condition where you kind of get, where are some other little clonal, you know, somatic mutations that you can get abnormalities in the epithelium that occur just in localized areas. That's not like loss of the cornified layer. We'll put a couple of other diseases where you see just local areas that are abnormal, and you get normal skin to the side. So, poro is one. We'll put",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'localized', 'concept_id': 'C0392752', 'confidence': 1.0}, {'entity': 'circumscribed area', 'concept_id': 'C1282914', 'confidence': 0.9260231852531433}, {'entity': 'granulomatous abnormalities', 'concept_id': 'C0439667', 'confidence': 0.7099277377128601}, {'entity': 'dyskeratotic keratinocytes', 'concept_id': 'C1512099', 'confidence': 0.9701507091522217}, {'entity': 'porokeratosis', 'concept_id': 'C0162839', 'confidence': 1.0}], [{'entity': 'loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'cornified layer', 'concept_id': 'C3554359', 'confidence': 0.8562335968017578}], [{'entity': 'conditions', 'concept_id': 'C0012634', 'confidence': 0.8556983470916748}, {'entity': 'localized', 'concept_id': 'C0392752', 'confidence': 1.0}, {'entity': 'abnormality', 'concept_id': 'C1704258', 'confidence': 1.0}, {'entity': 'somatic mutations', 'concept_id': 'C0544886', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_653",
"caption_rating": "9"
},
{
"": "1005933",
"caption": "Extravasated erythrocytes are frequently seen at the periphery of the tumor.",
"image_path": "8S4LeiO6Bbk_image_d45f4a7f-f27c-459c-980a-d6d5bc542879.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['dilated vascular channels', 'papillary projections', 'enlarged endothelial cells', 'compressed vascular channels', 'extravasated erythrocytes', 'dilated vascular channels', 'papillary projections', 'enlarged endothelial cells', 'compressed vascular channels', 'extravasated erythrocytes']",
"noisy_text": " which will slowly risk halt. These lesions will stain, frequently with CD34, but also are strongly positive for D240. So they probably are of lymphatic origin rather than vascular origin. What one looks for is a biphasic vascular tumor with this central area characterized by these dilated vascular channels. Let's look at the bottom piece, which frequently do contain these papillary projections, which protrude into the lumina, these plump endothelial cells, and then at the periphery, more compressed vascular channels, which dissect between collagen bundles. And it's at the periphery one frequently sees extravasated erythrocytes, siderophages, and",
"corrected_text": " which will slowly risk halt. These lesions will stain, frequently with CD34, but also are strongly positive for D240. So they probably are of lymphatic origin rather than vascular origin. What one looks for is a biphasic vascular tumor with this central area characterized by these dilated vascular channels. Let's look at the bottom piece, which frequently do contain these papillary projections, which protrude into the lumina, these plump endothelial cells, and then at the periphery, more compressed vascular channels, which dissect between collagen bundles. And it's at the periphery one frequently sees extravasated erythrocytes, siderophages, and",
"med_umls_ids": "[[{'entity': 'Lesions', 'concept_id': 'C0221198', 'confidence': 1.0}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'CD34', 'concept_id': 'C0054953', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'D240', 'concept_id': 'C3766973', 'confidence': 0.5323090553283691}, {'entity': 'lymphatic origin', 'concept_id': 'C0229889', 'confidence': 0.7706887125968933}, {'entity': 'vascular origin', 'concept_id': 'C0395959', 'confidence': 0.7819716334342957}], [{'entity': 'biphasic', 'concept_id': 'C0205184', 'confidence': 1.0}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'dilated', 'concept_id': 'C0700124', 'confidence': 0.9999999403953552}, {'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}, {'entity': 'central area', 'concept_id': 'C0929543', 'confidence': 0.8492603302001953}], [{'entity': 'Papillary projections', 'concept_id': 'C0016538', 'confidence': 0.7451471090316772}, {'entity': 'bottom piece', 'concept_id': 'C1511276', 'confidence': 0.722324788570404}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}], [{'entity': 'Enlarged endothelial cells', 'concept_id': 'C0423263', 'confidence': 0.7785332202911377}, {'entity': 'papillary projections', 'concept_id': 'C0016538', 'confidence': 0.7451471090316772}], [{'entity': 'Compressed vascular channels', 'concept_id': 'C1336948', 'confidence': 0.5993747711181641}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}], [{'entity': 'Extravasated', 'concept_id': 'C0015376', 'confidence': 0.868863582611084}, {'entity': 'erythrocytes', 'concept_id': 'C0014772', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_654",
"caption_rating": "9"
},
{
"": "1008123",
"caption": "Involvement around damaged nerves is a common feature of sarcoid granulomatous inflammation.",
"image_path": "udoW6VSqsm4_image_be0b36f7-3f7b-40b6-9863-de9ec37c56d8.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['sarcoid granulomatous inflammation', 'involvement around nerves']",
"noisy_text": " That's the tuberculoid. Yeah, good. The tuberculoid form of leprosy gives you sarcoidal granulomatous inflammation. It's elongated. Very good. That's exactly right. What else can give you sarcoidal granulomatous inflammation? Can I ask a quick question about the sarcoid with the two... The nansins? So, I had a case, I saw a case that looked kind of horizontal, but it was sarcoid. And so, what other ways can you tell? Sometimes it can be difficult, but usually you're going to see involvement around nerves damaged nerves. You're about to get sarcoidal granulomatous inflammation. They always have very high risk inflammatory reactions. They just wipe out the nerves. So, that's helpful. Wasn't",
"corrected_text": " That's the tuberculoid. Yeah, good. The tuberculoid form of leprosy gives you sarcoidal granulomatous inflammation. It's elongated. Very good. That's exactly right. What else can give you sarcoidal granulomatous inflammation? Can I ask a quick question about the sarcoid with the two... The sarcoidosis? So, I had a case, I saw a case that looked kind of horizontal, but it was sarcoid. And so, what other ways can you tell? Sometimes it can be difficult, but usually you're going to see involvement around nerves damaged nerves. You're about to get sarcoidal granulomatous inflammation. They always have very high risk inflammatory reactions. They just wipe out the nerves. So, that's helpful. Wasn't",
"med_umls_ids": "[[{'entity': 'Tuberculoid', 'concept_id': 'C0544783', 'confidence': 0.8459237217903137}, {'entity': 'leprosy', 'concept_id': 'C0023343', 'confidence': 1.0}, {'entity': 'sarcoid', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'granulomatous inflammation', 'concept_id': 'C0553697', 'confidence': 1.0}], [{'entity': 'Involvement', 'concept_id': 'C1314939', 'confidence': 1.0}, {'entity': 'damaged nerves', 'concept_id': 'C3887709', 'confidence': 0.8087002038955688}, {'entity': 'sarcoid', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'granulomatous inflammation', 'concept_id': 'C0553697', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_655",
"caption_rating": "8"
},
{
"": "1004910",
"caption": "Presence of sarcoid-like granulomas in the lung of the patient who was taking TNF for ankylosing spondylitis.",
"image_path": "sDFjOtMAYrk_image_28ef14be-0add-40bb-a12d-4686de00f1ea.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['Sarcoid-like granulomas in the lung.']",
"noisy_text": " patients who develop sarcoid-like granulomas, at least in the lung. So maybe the process just takes a little while to resolve after the patient's taken off the drug. Yeah, so the patient, we did all the stains, albeit they're low yield. The patient had no risk factors for TB. They never tested him for TB, though. But they thought clinically, that's not an issue. He got tested for a couple of other things. His ACE was within normal limits, and yeah, nothing. He just removed the drug and said, okay, let's see if this works. And that turned out to be the patient had, he was taking TNF for ankylosing spondylitis. Ankylosing spondylitis, yeah. Coming back to our",
"corrected_text": " patients who develop sarcoid-like granulomas, at least in the lung. So maybe the process just takes a little while to resolve after the patient's taken off the drug. Yeah, so the patient, we did all the stains, albeit they're low yield. The patient had no risk factors for TB. They never tested him for TB, though. But they thought clinically, that's not an issue. He got tested for a couple of other things. His ACE was within normal limits, and yeah, nothing. He just removed the drug and said, okay, let's see if this works. And that turned out to be the patient had, he was taking TNF for ankylosing spondylitis. Ankylosing spondylitis, yeah. Coming back to our",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'sarcoid-like granulomas', 'concept_id': 'C0333419', 'confidence': 0.7742165923118591}, {'entity': 'lung', 'concept_id': 'C0024109', 'confidence': 1.0}, {'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'TNF', 'concept_id': 'C0812246', 'confidence': 1.0}, {'entity': 'ankylosing spondylitis', 'concept_id': 'C0038013', 'confidence': 1.0}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'risk factors', 'concept_id': 'C0035648', 'confidence': 1.0}, {'entity': 'TB', 'concept_id': 'C0041296', 'confidence': 1.0}, {'entity': 'ACE', 'concept_id': 'C0050385', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_656",
"caption_rating": "9"
},
{
"": "1004251",
"caption": "The myxoid areas in the low-grade fibromyxoid sarcoma look different from the fibrous areas.",
"image_path": "QDb68_G1HR4_image_ca0e2f46-8d10-415b-995e-fc44a120a6b2.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " kind of rounded or triangle shaped but even still we really just don't see anything that looks like marked atypia or pleomorphism which is distinctly different from myxofibrosarcoma which again I have another video about that I'll put a link in the video description and up in the upper right hand corner. Myxofibrosarcomas are by definition pleomorphic sarcomas, they're aneuploid, they do not have translocations, they have random gains and losses and thus they have pleomorphism. So even in the grade 1, the low grade form of myxofibrosarcoma, you have to have pleomorphism, that's a different tumor than this low grade fibromyxoid sarcoma or Evans tumor which usually does not have pleomorphism, okay? So the myxoid areas here look a little different than the fibrous areas. So I'm",
"corrected_text": " kind of rounded or triangle shaped but even still we really just don't see anything that looks like marked atypia or pleomorphism which is distinctly different from myxofibrosarcoma which again I have another video about that I'll put a link in the video description and up in the upper right hand corner. myxofibrosarcoma are by definition pleomorphic sarcomas, they're aneuploid, they do not have translocations, they have random gains and losses and thus they have pleomorphism. So even in the grade 1, the low grade form of myxofibrosarcoma, you have to have pleomorphism, that's a different tumor than this low grade fibromyxoid sarcoma or Evans tumor which usually does not have pleomorphism, okay? So the myxoid areas here look a little different than the fibrous areas. So I'm",
"med_umls_ids": "[[{'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'Evans tumor', 'concept_id': 'C2697858', 'confidence': 0.6359843015670776}, {'entity': 'pleomorphism', 'concept_id': 'C0032219', 'confidence': 1.0}, {'entity': 'myxofibrosarcoma', 'concept_id': 'C3714524', 'confidence': 1.0}], [{'entity': 'Myxofibrosarcoma', 'concept_id': 'C3714524', 'confidence': 1.0}, {'entity': 'pleomorphic sarcoma', 'concept_id': 'C1261358', 'confidence': 0.9260651469230652}, {'entity': 'aneuploidy', 'concept_id': 'C0002938', 'confidence': 1.0}, {'entity': 'random', 'concept_id': 'C0034656', 'confidence': 1.0}, {'entity': 'gains', 'concept_id': 'C1517378', 'confidence': 0.7974324226379395}, {'entity': 'losses', 'concept_id': 'C0018840', 'confidence': 0.786555290222168}], [{'entity': 'myxoid areas', 'concept_id': 'C0205295', 'confidence': 0.8464413285255432}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'fibrous areas', 'concept_id': 'C0439709', 'confidence': 0.783623218536377}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_657",
"caption_rating": "8"
},
{
"": "1008182",
"caption": "The absence of hyalinization in the lamina propria does not exclude ischemia, as recent ischemia may not have had time to cause hyalinization.",
"image_path": "sDFjOtMAYrk_image_7a3e5842-9e70-46aa-9b43-ef5366ec922b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['Clostridioides difficile colitis', 'lamina propria', 'hyalinization']",
"noisy_text": " will give you pseudomembranes. Ischemic injury can also give it to you. And the one thing to note is that, so this patient had C. difficile colitis by laboratory, but he was not responding to treatment and they just decided to take a biopsy. And you can see here that in the lamina propria is not hyalinized. Now, does that mean that ischemia is excluded? No, because if it's, you know, it depends on the clinical history. If it's recent ischemia that happened within, I don't know, 24, 48 hours, you know, the hyalinopropia may not have had time to hyalinize. How",
"corrected_text": " will give you pseudomembranes. Ischemic injury can also give it to you. And the one thing to note is that, so this patient had C. difficile colitis by laboratory, but he was not responding to treatment and they just decided to take a biopsy. And you can see here that in the lamina propria is not hyalinized. Now, does that mean that ischemia is excluded? No, because if it's, you know, it depends on the clinical history. If it's recent ischemia that happened within, I don't know, 24, 48 hours, you know, the hyalinization may not have had time to hyalinize. How",
"med_umls_ids": "[[{'entity': 'Pseudomembranes', 'concept_id': 'C0240821', 'confidence': 1.0}, {'entity': 'Clostridioides', 'concept_id': 'C4406271', 'confidence': 1.0}, {'entity': 'colitis', 'concept_id': 'C0009319', 'confidence': 1.0}, {'entity': 'ischemic injury', 'concept_id': 'C2945681', 'confidence': 0.8915668725967407}], [{'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'hyalinization', 'concept_id': 'C0333438', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}, {'entity': 'hyalinization', 'concept_id': 'C0333438', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_658",
"caption_rating": "9"
},
{
"": "1009445",
"caption": "The nuclei are reaching the middle third and maintaining polarity.",
"image_path": "r7OA0Trj5hQ_image_89087849-ec8f-4550-8740-0151d00b6738.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " that is pathologic in this biopsy. And there is mitosis and apoptosis. Remember, these four criteria for dysplasia. See again here, stratification has started. But you see, mucin is less. It is, I won't say lost. It is less. And this stratified nuclei reach the middle third. They are not touching the upper top of the apical membrane. They are reaching the middle third predominantly. Okay, that is one important point. And other one is, look at this nuclei. They are all traveling in one direction. So the polarity is maintained. Okay, so those two points are very important. And the third one",
"corrected_text": " that is pathologic in this biopsy. And there is mitosis and apoptosis. Remember, these four criteria for dysplasia. See again here, stratification has started. But you see, mucin is less. It is, I won't say lost. It is less. And this stratified nuclei reach the middle third. They are not touching the upper top of the apical membrane. They are reaching the middle third predominantly. Okay, that is one important point. And other one is, look at this nuclei. They are all traveling in one direction. So the polarity is maintained. Okay, so those two points are very important. And the third one",
"med_umls_ids": "[[{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'pathologic', 'concept_id': 'C1521733', 'confidence': 1.0}, {'entity': 'mitosis', 'concept_id': 'C0026255', 'confidence': 0.9999998807907104}, {'entity': 'apoptosis', 'concept_id': 'C0162638', 'confidence': 1.0}], [{'entity': 'Stratification', 'concept_id': 'C1514983', 'confidence': 1.0}, {'entity': 'started', 'concept_id': 'C1272689', 'confidence': 0.9999999403953552}, {'entity': 'mucin', 'concept_id': 'C0026682', 'confidence': 1.0}], [{'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'middle', 'concept_id': 'C0227972', 'confidence': 1.0}, {'entity': 'polarity', 'concept_id': 'C0596963', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_659",
"caption_rating": "8"
},
{
"": "1006859",
"caption": "Too many melanocytes in the matrix are highly suspicious for melanoma in situ.",
"image_path": "8S4LeiO6Bbk_image_759de876-54a9-488a-8cee-29032ba566e8.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Presence of several melanocytes', 'too many melanocytes', 'Presence of several melanocytes', 'too many melanocytes']",
"noisy_text": " examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matricle epithelium in the matricle layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that being said, we'll go ahead and move on to slide number two, which was a melanin A or Mk1 immunohistochemical stain of this same piece of tissue. Underneath this bubble here we have our control. This is",
"corrected_text": " examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matrix epithelium in the matrix layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that being said, we'll go ahead and move on to slide number two, which was a melanin A or Mk1 immunohistochemical stain of this same piece of tissue. Underneath this bubble here we have our control. This is",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'nests', 'concept_id': 'C0035253', 'confidence': 0.7275967001914978}, {'entity': 'confluence', 'concept_id': 'C0226863', 'confidence': 0.857487678527832}, {'entity': 'solitary units', 'concept_id': 'C0205171', 'confidence': 0.7227572798728943}, {'entity': 'base', 'concept_id': 'C0002055', 'confidence': 1.0}, {'entity': 'matrix epithelium', 'concept_id': 'C0014609', 'confidence': 0.7584323883056641}, {'entity': 'matrix layer', 'concept_id': 'C0331858', 'confidence': 0.71736741065979}, {'entity': 'basal layer', 'concept_id': 'C0221925', 'confidence': 1.0}, {'entity': 'matrix', 'concept_id': 'C0331858', 'confidence': 1.0}, {'entity': 'upper portions', 'concept_id': 'C0449719', 'confidence': 0.6251541972160339}, {'entity': 'matrix', 'concept_id': 'C0331858', 'confidence': 1.0}, {'entity': 'pagetoid', 'concept_id': 'C1518847', 'confidence': 0.8801172375679016}, {'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}], [{'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'matrix', 'concept_id': 'C0331858', 'confidence': 1.0}, {'entity': 'suspicious', 'concept_id': 'C0750493', 'confidence': 1.0}, {'entity': 'melanoma', 'concept_id': 'C0025202', 'confidence': 1.0}, {'entity': 'in situ', 'concept_id': 'C0444498', 'confidence': 0.9999999403953552}]]",
"magnification": "1.0",
"height": "758.0",
"width": "1920.0",
"id": "test_660",
"caption_rating": "8"
},
{
"": "1004485",
"caption": "Trichofolliculoma with miniaturized hair follicles and prominent stroma.",
"image_path": "LlPaENuqzVQ_image_047f29e5-94de-455a-a3af-e7e5ce33dfc8.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['miniaturized hair follicles', 'prominent stroma']",
"noisy_text": " This is another lesion, okay. And this one is kind of cut in cross section, but this one had a lot of little miniaturized follicles here. And each one of these is surrounded by this kind of fairly prominent stroma. This is sort of a tricofolliculoma cut adjacent to the really the central cyst. And the tricofolliculoma has got a little cyst with these little miniaturized hair follicles that are radiating from the central cyst component of the lesion. So this is off to the side of it. But you can see that these follicular neoplasms, they pretty much commonly do have this stroma that you",
"corrected_text": " This is another lesion, okay. And this one is kind of cut in cross section, but this one had a lot of little miniaturized follicles here. And each one of these is surrounded by this kind of fairly prominent stroma. This is sort of a trichofolliculoma cut adjacent to the really the central cyst. And the trichofolliculoma has got a little cyst with these little miniaturized hair follicles that are radiating from the central cyst component of the lesion. So this is off to the side of it. But you can see that these follicular neoplasms, they pretty much commonly do have this stroma that you",
"med_umls_ids": "[[{'entity': 'Trichofolliculoma', 'concept_id': 'C0334262', 'confidence': 1.0}, {'entity': 'miniaturized hair follicles', 'concept_id': 'C0221971', 'confidence': 0.7287319302558899}, {'entity': 'stroma', 'concept_id': 'C0927195', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_661",
"caption_rating": "9"
},
{
"": "1005403",
"caption": "Presence of neutrophils in surface epithelium.",
"image_path": "r7OA0Trj5hQ_image_08f3aa85-fe3d-4f39-b651-8b094e657890.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['hemorrhage', 'extensive ulceration', 'hemorrhage', 'gastric mucosa', 'willy-formed changes', 'chemical gastritis', 'antrum', 'pylorus', 'neutrophils']",
"noisy_text": " Extensive ulceration and hemorrhage. As far as the poisoning, any other chemicals, or any chemotherapy, clinical history is very, very important to make a exact diagnosis. This is the surface epithelial changes where the surface looks more willy-formed. This is a gastric, if it is small intestine, then it is fine, but this is a gastric mucosa. You see a lot of willy-formed changes. These willy-formed changes are very important in the diagnosis of chemical gastritis if the biopsy is taken from the antrum or pylorus. What happens there? The bile is trying to come into the stomach, so the stomach is trying to become small intestine. That's why you see willy-formed changes in the chemical gastritis. Here, what do you see in the surface epithelium? See, a lot of neutrophils are sitting. Remember, I told you, this is",
"corrected_text": " Extensive ulceration and hemorrhage. As far as the poisoning, any other chemicals, or any chemotherapy, clinical history is very, very important to make a exact diagnosis. This is the surface epithelial changes where the surface looks more willy-formed. This is a gastric, if it is small intestine, then it is fine, but this is a gastric mucosa. You see a lot of willy-formed changes. These willy-formed changes are very important in the diagnosis of chemical gastritis if the biopsy is taken from the antrum or pylorus. What happens there? The bile is trying to come into the stomach, so the stomach is trying to become small intestine. That's why you see willy-formed changes in the chemical gastritis. Here, what do you see in the surface epithelium? See, a lot of neutrophils are sitting. Remember, I told you, this is",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'extensive', 'concept_id': 'C0205231', 'confidence': 1.0}, {'entity': 'ulceration', 'concept_id': 'C0041582', 'confidence': 1.0}, {'entity': 'hemorrhage', 'concept_id': 'C0019080', 'confidence': 1.0}], [{'entity': 'Clinical history', 'concept_id': 'C5204342', 'confidence': 0.9999999403953552}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'poisoning', 'concept_id': 'C0032343', 'confidence': 1.0}, {'entity': 'exposure to', 'concept_id': 'C0332157', 'confidence': 0.9999998807907104}, {'entity': 'chemicals', 'concept_id': 'C0220806', 'confidence': 1.0}, {'entity': 'chemotherapy', 'concept_id': 'C0013216', 'confidence': 1.0}], [{'entity': 'Surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'epithelial changes', 'concept_id': 'C0221908', 'confidence': 0.7544435858726501}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'gastric mucosa', 'concept_id': 'C0017136', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}, {'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'antrum', 'concept_id': 'C0034193', 'confidence': 1.0}, {'entity': 'pylorus', 'concept_id': 'C0034196', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'surface epithelium', 'concept_id': 'C1182809', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_662",
"caption_rating": "9"
},
{
"": "1009104",
"caption": "Presence of at least two cell types with round to oval nuclei and faint eosinophilic to pale gray cytoplasm.",
"image_path": "8S4LeiO6Bbk_image_1e8d3c8f-6507-4fdb-b5cf-6edd5afdfe9f.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['lymphocytes', 'epithelial tumor', 'cytoplasm', 'vesicular chromatin pattern', 'lymphocytes', 'duct formation', 'cytoplasm']",
"noisy_text": " If we move to higher power, we can see that we're dealing with an epithelial rather than a mosaicable tumor. We've got interconnected cords and strands. We have somewhat of a ribiform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of the cells are round to oval. They're fairly large. These cells have some faint eosinophilic to pale gray cytoplasm, although this cytoplasm is kind of difficult to see. Some of these cells have an evenly dispersed or vesicular chromatin pattern, and other nuclei are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and",
"corrected_text": " If we move to higher power, we can see that we're dealing with an epithelial rather than a mesenchymal tumor. We've got interconnected cords and strands. We have somewhat of a cribriform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of the cells are round to oval. They're fairly large. These cells have some faint eosinophilic to pale gray cytoplasm, although this cytoplasm is kind of difficult to see. Some of these cells have an evenly dispersed or vesicular chromatin pattern, and other nuclei are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'epithelial tumor', 'concept_id': 'C1368683', 'confidence': 0.9999999403953552}, {'entity': 'cords', 'concept_id': 'C0034869', 'confidence': 0.801885187625885}, {'entity': 'strands', 'concept_id': 'C0600383', 'confidence': 0.800572395324707}], [{'entity': 'Cribriform pattern', 'concept_id': 'C1333163', 'confidence': 1.0}, {'entity': 'loose', 'concept_id': 'C0205407', 'confidence': 1.0}, {'entity': 'edematous', 'concept_id': 'C0013604', 'confidence': 1.0}, {'entity': 'vascular stroma', 'concept_id': 'C0005847', 'confidence': 0.8046398758888245}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'cell types', 'concept_id': 'C0007634', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'eosinophilic', 'concept_id': 'C0333930', 'confidence': 1.0}, {'entity': 'pale', 'concept_id': 'C0030232', 'confidence': 1.0}, {'entity': 'gray cytoplasm', 'concept_id': 'C0010834', 'confidence': 0.8177905678749084}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'duct', 'concept_id': 'C0687028', 'confidence': 1.0}, {'entity': 'formation', 'concept_id': 'C0220781', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_663",
"caption_rating": "8"
},
{
"": "1005424",
"caption": "The lesion tends to occur along the ulnar aspect of the fifth digit and can be bilateral.",
"image_path": "8S4LeiO6Bbk_image_dc3ed701-9eb6-43b7-962b-73d799d61318.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['ulnar aspect of the fifth digit']",
"noisy_text": " core here we've got several well-defined nerve fascicles and the spindled cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions of course tend to occur along the ulnar eye aspect of the fifth digit. They're not infrequently bilateral and the key differential here of course is an acquired digital fibroma or an acquired digital fibrocarotoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if",
"corrected_text": " core here we've got several well-defined nerve fascicles and the spindle cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions of course tend to occur along the ulnar eye aspect of the fifth digit. They're not infrequently bilateral and the key differential here of course is an acquired digital fibroma or an acquired digital fibrokeratoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if",
"med_umls_ids": "[[{'entity': 'Well-defined nerve fascicles', 'concept_id': 'C1185741', 'confidence': 0.5682494640350342}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'S100', 'concept_id': 'C3273837', 'confidence': 1.0}, {'entity': 'SOX10', 'concept_id': 'C1420317', 'confidence': 0.9999998807907104}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'rudimentary supernumerary digit', 'concept_id': 'C0152427', 'confidence': 0.8142021894454956}], [{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'ulnar', 'concept_id': 'C0442044', 'confidence': 1.0}, {'entity': 'aspect', 'concept_id': 'C1547011', 'confidence': 1.0}, {'entity': 'fifth digit', 'concept_id': 'C0230403', 'confidence': 0.912693440914154}, {'entity': 'bilateral', 'concept_id': 'C0238767', 'confidence': 1.0}], [{'entity': 'differential diagnosis', 'concept_id': 'C0011906', 'confidence': 1.0}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}, {'entity': 'digital fibroma', 'concept_id': 'C4538745', 'confidence': 0.8997364640235901}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}], [{'entity': 'Trichilemmal cyst', 'concept_id': 'C2266788', 'confidence': 1.0}, {'entity': 'biopsy specimen', 'concept_id': 'C0677862', 'confidence': 1.0}, {'entity': 'slide number', 'concept_id': 'C3828004', 'confidence': 0.8261933326721191}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_664",
"caption_rating": "8"
},
{
"": "1008006",
"caption": "Sebaceomas are usually small, round, and skin-colored.",
"image_path": "udoW6VSqsm4_image_3a789541-9419-4967-a4d9-8751d3c6c93d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['sebaceoma', 'basal cell carcinoma', 'sebaceous differentiation', 'sebaceoma', 'basal cell carcinoma', 'sebaceous differentiation']",
"noisy_text": " I think we've called it sebaceous epithelium, but again I'm not a big fan of that term. And these look usually like this. They're usually small, round, skin-colored leaves. They kind of look like sebaceous epithelium. They usually come in as real-life basins, so nobody diagnoses these clinically correctly. So these are items in the differential diagnosis. Basal cell with sebaceous differentiation, if you're going to make that diagnosis, it generally needs to look like a basal cell with nice clefting and put the palisade in there and all that, and then have foci where there's obvious sebaceous differentiation. You'll see that on occasion. But I would probably call this sebaceoma, without thinking it's sort of synonymous with sebaceous epithelium. Now, is there any condition you have to worry about with these? With any",
"corrected_text": " I think we've called it sebaceous epithelium, but again I'm not a big fan of that term. And these look usually like this. They're usually small, round, skin-colored leaves. They kind of look like sebaceous epithelium. They usually come in as real-life basins, so nobody diagnoses these clinically correctly. So these are items in the differential diagnosis. Basal cell with sebaceous differentiation, if you're going to make that diagnosis, it generally needs to look like a basal cell with nice clefting and put the palisade in there and all that, and then have foci where there's obvious sebaceous differentiation. You'll see that on occasion. But I would probably call this sebaceoma, without thinking it's sort of synonymous with sebaceous epithelium. Now, is there any condition you have to worry about with these? With any",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'sebaceoma', 'concept_id': 'C1275210', 'confidence': 1.0}, {'entity': 'basal cell carcinoma', 'concept_id': 'C0007117', 'confidence': 1.0}, {'entity': 'sebaceous differentiation', 'concept_id': 'C1882988', 'confidence': 1.0}], [{'entity': 'Sebaceomas', 'concept_id': 'C1275210', 'confidence': 0.8855459690093994}, {'entity': 'small', 'concept_id': 'C0700321', 'confidence': 0.9999998807907104}, {'entity': 'round', 'concept_id': 'C0332490', 'confidence': 1.0}, {'entity': 'skin-colored', 'concept_id': 'C4476819', 'confidence': 0.8005288243293762}], [{'entity': 'Basal cell carcinoma', 'concept_id': 'C0007117', 'confidence': 1.0}, {'entity': 'sebaceous differentiation', 'concept_id': 'C1882988', 'confidence': 1.0}, {'entity': 'clefting', 'concept_id': 'C4021813', 'confidence': 0.8906428217887878}, {'entity': 'palisading', 'concept_id': 'C1622240', 'confidence': 0.8684062361717224}, {'entity': 'sebaceous differentiation', 'concept_id': 'C1882988', 'confidence': 1.0}], [{'entity': 'conditions', 'concept_id': 'C0012634', 'confidence': 0.8556983470916748}, {'entity': 'concern', 'concept_id': 'C2699424', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_665",
"caption_rating": "7"
},
{
"": "1005821",
"caption": "The key differential diagnosis is an acquired digital fibroma or an acquired digital fibrokeratoma.",
"image_path": "8S4LeiO6Bbk_image_05eec250-fd22-4ed8-93df-a011dc2c30f2.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['nerve fascicles', 'spindle-shaped cells', 'rudimentary supernumerary digit', 'ulnar aspect of the fifth digit', 'acquired digital fibroma', 'acquired digital fibrokeratoma', 'trichilemmal cyst', 'nerve fascicles', 'spindle-shaped cells', 'rudimentary supernumerary digit', 'ulnar aspect of the fifth digit', 'acquired digital fibroma', 'acquired digital fibrokeratoma', 'trichilemmal cyst', 'nerve fascicles', 'spindle-shaped cells', 'rudimentary supernumerary digit', 'ulnar aspect of the fifth digit', 'acquired digital fibroma', 'acquired digital fibrokeratoma', 'trichilemmal cyst']",
"noisy_text": " core here we've got several well-defined nerve fascicles and the spindled cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions of course tend to occur along the ulnar eye aspect of the fifth digit. They're not infrequently bilateral and the key differential here of course is an acquired digital fibroma or an acquired digital fibrocarotoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if",
"corrected_text": " core here we've got several well-defined nerve fascicles and the spindle cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions of course tend to occur along the ulnar eye aspect of the fifth digit. They're not infrequently bilateral and the key differential here of course is an acquired digital fibroma or an acquired digital fibrokeratoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if",
"med_umls_ids": "[[{'entity': 'Well-defined nerve fascicles', 'concept_id': 'C1185741', 'confidence': 0.5682494640350342}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'S100', 'concept_id': 'C3273837', 'confidence': 1.0}, {'entity': 'SOX10', 'concept_id': 'C1420317', 'confidence': 0.9999998807907104}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'rudimentary supernumerary digit', 'concept_id': 'C0152427', 'confidence': 0.8142021894454956}], [{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'ulnar', 'concept_id': 'C0442044', 'confidence': 1.0}, {'entity': 'aspect', 'concept_id': 'C1547011', 'confidence': 1.0}, {'entity': 'fifth digit', 'concept_id': 'C0230403', 'confidence': 0.912693440914154}, {'entity': 'bilateral', 'concept_id': 'C0238767', 'confidence': 1.0}], [{'entity': 'differential diagnosis', 'concept_id': 'C0011906', 'confidence': 1.0}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}, {'entity': 'digital fibroma', 'concept_id': 'C4538745', 'confidence': 0.8997364640235901}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}], [{'entity': 'Trichilemmal cyst', 'concept_id': 'C2266788', 'confidence': 1.0}, {'entity': 'biopsy specimen', 'concept_id': 'C0677862', 'confidence': 1.0}, {'entity': 'slide number', 'concept_id': 'C3828004', 'confidence': 0.8261933326721191}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_666",
"caption_rating": "8"
},
{
"": "1008224",
"caption": "Vesicular nuclei are usually accompanied by a nucleoli.",
"image_path": "Wiyo6taYRF4_image_f2fd3cc2-b10f-44d2-aa3a-167b1cde6571.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Hematopathology', 'Neuropathology', 'Cytopathology']",
"roi_text": "['neuroendocrine carcinoma', 'hyperchromatic nuclei', 'vesicular nuclei', 'nucleoli', 'salt and pepper chromatin', 'nucleoli', 'salt and pepper chromatin']",
"noisy_text": " and pepper like copper chromatin, that means you're telling that this is most likely a neuroendocrine kind of a carcinoma. So those are the different types of nuclei that we have seen. Again, to go back at the reference, we are going to look at the plasma cell. In the plasma cell, we can easily identify the hetero and the vesicular areas, that is heterochromatin and nucleomatin. If the cell is entirely composed of heterochromatin, it will be very dark-staining. And this is called as hyperchromatic nuclei. If it is composed of lightly-stained nuclei, lightly-stained areas, then it is called vesicular nuclei. A vesicular nuclei is usually accompanied by a nucleoli. And if you have very finely granular dark and light areas, then it is called as salt and pepper chromatin. And these are the defining features for a neuroendocrine tumor. Now, once we have understood the staining pattern of the",
"corrected_text": " and pepper like copper chromatin, that means you're telling that this is most likely a neuroendocrine kind of a carcinoma. So those are the different types of nuclei that we have seen. Again, to go back at the reference, we are going to look at the plasma cell. In the plasma cell, we can easily identify the hetero and the vesicular areas, that is heterochromatin and nucleoplasm. If the cell is entirely composed of heterochromatin, it will be very hyperchromatic. And this is called as hyperchromatic nuclei. If it is composed of lightly-stained areas, lightly-stained areas, then it is called vesicular nuclei. A vesicular nuclei is usually accompanied by a nucleoli. And if you have very finely granular dark and light areas, then it is called as salt and pepper chromatin. And these are the defining features for a neuroendocrine tumor. Now, once we have understood the staining pattern of the",
"med_umls_ids": "[[{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'pepper-like copper chromatin', 'concept_id': 'C0453397', 'confidence': 0.5605897903442383}, {'entity': 'neuroendocrine carcinoma', 'concept_id': 'C0206695', 'confidence': 1.0}], [{'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'observed', 'concept_id': 'C1441672', 'confidence': 1.0}, {'entity': 'hyperchromatic', 'concept_id': 'C0333911', 'confidence': 1.0}, {'entity': 'vesicular nuclei', 'concept_id': 'C2325471', 'confidence': 0.7651268839836121}], [{'entity': 'Heterochromatin', 'concept_id': 'C0019397', 'confidence': 1.0}, {'entity': 'nucleoplasm', 'concept_id': 'C0682537', 'confidence': 1.0}, {'entity': 'identified', 'concept_id': 'C0205396', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}], [{'entity': 'Vesicular nuclei', 'concept_id': 'C2325471', 'confidence': 0.7651268839836121}, {'entity': 'nucleoli', 'concept_id': 'C0007609', 'confidence': 0.8710004091262817}], [{'entity': 'Salt', 'concept_id': 'C0036140', 'confidence': 1.0}, {'entity': 'pepper chromatin', 'concept_id': 'C0008546', 'confidence': 0.7025638818740845}, {'entity': 'neuroendocrine tumor', 'concept_id': 'C0206754', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1152.0",
"id": "test_667",
"caption_rating": "8"
},
{
"": "1008046",
"caption": "Neutrophils in the epithelium indicate cryptitis, which may be related to H. pylori infection.",
"image_path": "r7OA0Trj5hQ_image_00149080-9436-445e-9c8c-ee023801ce61.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Gastric biopsy for H. pylori with crypt abscess', 'Neutrophils in the epithelium indicating cryptitis']",
"noisy_text": " Please remember, presence of lymphocytes and plasma cells is not a feature of chronicity. But architectural change by the way of irregular size, shape, and distributed glands is an indication of chronicity. Criteria for chronicity. Yeah, you see nicely neutrophils sitting in the epithelium. Can you all see neutrophils sitting in the epithelium? So this is cryptitis. It is stomach, even though I'm using the term. But I just want to know whether you are able to understand or not. This is a gastric biopsy where you have to look for H. pylori because the H. pylori secrete some chemotactic factors for neutrophils. That's why the neutrophils come. And this is a crypt abscess. This is",
"corrected_text": " Please remember, presence of lymphocytes and plasma cells is not a feature of chronicity. But architectural change by the way of irregular size, shape, and distributed glands is an indication of chronicity. Criteria for chronicity. Yeah, you see nicely neutrophils sitting in the epithelium. Can you all see neutrophils sitting in the epithelium? So this is cryptitis. It is stomach, even though I'm using the term. But I just want to know whether you are able to understand or not. This is a gastric biopsy where you have to look for H. pylori because the H. pylori secrete some chemotactic factors for neutrophils. That's why the neutrophils come. And this is a crypt abscess. This is",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'chronicity', 'concept_id': 'C0547045', 'confidence': 1.0}, {'entity': 'architectural', 'concept_id': 'C0003737', 'confidence': 0.8758222460746765}, {'entity': 'changes', 'concept_id': 'C0392747', 'confidence': 1.0}, {'entity': 'gland size', 'concept_id': 'C0426336', 'confidence': 0.8790121674537659}, {'entity': 'shape', 'concept_id': 'C0332479', 'confidence': 1.0}, {'entity': 'distribution', 'concept_id': 'C0037775', 'confidence': 1.0}, {'entity': 'chronicity', 'concept_id': 'C0547045', 'confidence': 1.0}], [{'entity': 'Neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'cryptitis', 'concept_id': 'C1394254', 'confidence': 0.9999998807907104}, {'entity': 'H. pylori infection', 'concept_id': 'C0850666', 'confidence': 0.9999999403953552}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_668",
"caption_rating": "8"
},
{
"": "1008106",
"caption": "Description of a benign-looking tumor with delicate stringy fine collagen and bland fibroblastic looking cells. The importance of recognizing the histologic pattern to correctly diagnose tumors.",
"image_path": "QDb68_G1HR4_image_ae28a03a-1833-459f-98f6-722483ce7f44.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['fibroblastic looking cells']",
"noisy_text": " Let me flip the condenser back so we can see it more clearly. So this is what it looks like without the condenser on, again, very delicate stringy fine collagen and in between these bland, bland, thin, not atypical at all, fibroblastic looking cells. And I could show anyone a picture of that, one picture. That does not look malignant, it looks totally benign by all of the rules that we usually use to assess malignancy histologically and cytologically. This is the most important take home point from this whole video. These tumors do not usually look malignant and because of that if you don't recognize the pattern, it is so easy to misdiagnose them as a benign thing. So I think a couple ways to avoid that is A, don't look at this and say, oh look it's a benign and it looks fibroblastic, let's call it a fibroma, don't do that. The other thing, one of my mentors, one of my greatest mentors, the one who made me decide to pursue academic medicine and teaching, Dr. Jay Rowe from Houston Methodist Hospital, what he told me, it was I think some great advice, he said if you see a lesion that you think is a neoplasm and you think it's a benign neoplasm but you don't know a name for it, don't just sign it out and diagnose it as benign neoplasm, not otherwise specified unless you're an expert in that particular subspecialty. Go and show it to an expert if you have a case like that and the reason is that maybe most of the time you'll be okay doing that but you're going to end up having things like this that are known entities that don't look malignant. In soft tissue we have quite a few of these, we have low grade fibromyxoid sarcoma, myxoid liposarcoma also looks totally benign most of the time unless you recognize the pattern. So this is another one of those tumors where the histologic pattern is really the key to recognizing the diagnosis. So I'm going to go in even higher power to convince you, yes these are sarcoma cells right here.",
"corrected_text": " Let me flip the condenser back so we can see it more clearly. So this is what it looks like without the condenser on, again, very delicate stringy fine collagen and in between these bland, bland, thin, not atypical at all, fibroblastic looking cells. And I could show anyone a picture of that, one picture. That does not look malignant, it looks totally benign by all of the rules that we usually use to assess malignancy histologically and cytology. This is the most important take home point from this whole video. These tumors do not usually look malignant and because of that if you don't recognize the pattern, it is so easy to misdiagnose them as a benign thing. So I think a couple ways to avoid that is A, don't look at this and say, oh look it's a benign and it looks fibroblastic, let's call it a fibroma, don't do that. The other thing, one of my mentors, one of my greatest mentors, the one who made me decide to pursue academic medicine and teaching, Dr. Jay Rowe from Houston Methodist Hospital, what he told me, it was I think some great advice, he said if you see a lesion that you think is a neoplasm and you think it's a benign neoplasm but you don't know a name for it, don't just sign it out and diagnose it as benign neoplasm, not otherwise specified unless you're an expert in that particular subspecialty. Go and show it to an expert if you have a case like that and the reason is that maybe most of the time you'll be okay doing that but you're going to end up having things like this that are known entities that don't look malignant. In soft tissue we have quite a few of these, we have low grade fibromyxoid sarcoma, myxoid liposarcoma also looks totally benign most of the time unless you recognize the pattern. So this is another one of those tumors where the histologic pattern is really the key to recognizing the diagnosis. So I'm going to go in even higher power to convince you, yes these are sarcoma cells right here.",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'benign-looking tumor', 'concept_id': 'C0086692', 'confidence': 0.5747699737548828}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'bland', 'concept_id': 'C0227475', 'confidence': 0.7435316443443298}, {'entity': 'fibroblastic', 'concept_id': 'C0016030', 'confidence': 0.8876925110816956}, {'entity': 'histologic', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_669",
"caption_rating": "8"
},
{
"": "1007433",
"caption": "Possible presence of intracellular intracytoplasmic neutrophils and degenerating vacuoles.",
"image_path": "sDFjOtMAYrk_image_f5e1c62e-602e-4f58-823f-8c8d482be39e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "[]",
"noisy_text": " they're receiving radiation, is a lot of eosinophils and even intracryptal eosinophilic microapses. You don't see a lot in the way of neutrophils. You may see some neutrophils in the cytoplasm of the nuclei, like intracellular intracytoplasmic neutrophils, but not really neutrophilic microapses. And the other thing you might see is intracytoplasmic vacuoles degenerating vacuoles. So, this is a good example of chemotherapy associated colitis, a mimic of inflammatory bowel disease. Oh, this is a good one. With that degree, the mild degree of architectural distortion is what's making me fall short of saying this is for sure IBD. So, I would be descriptive and I would say, you know,",
"corrected_text": " they're receiving radiation, is a lot of eosinophils and even intracryptal eosinophilic microapses. You don't see a lot in the way of neutrophils. You may see some neutrophils in the cytoplasm of the nuclei, like intracellular intracytoplasmic neutrophils, but not really neutrophilic microapses. And the other thing you might see is intracytoplasmic vacuoles degenerating vacuoles. So, this is a good example of chemotherapy associated colitis, a mimic of inflammatory bowel disease. Oh, this is a good one. With that degree, the mild degree of architectural distortion is what's making me fall short of saying this is for sure IBD. So, I would be descriptive and I would say, you know,",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'intracryptal', 'concept_id': 'C3315370', 'confidence': 0.626490592956543}, {'entity': 'microapses', 'concept_id': 'C0700712', 'confidence': 0.5626617074012756}, {'entity': 'patients', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'radiation', 'concept_id': 'C0034519', 'confidence': 1.0}], [{'entity': 'intracellular', 'concept_id': 'C0175996', 'confidence': 1.0}, {'entity': 'intracytoplasmic', 'concept_id': 'C0230649', 'confidence': 0.8670988082885742}, {'entity': 'neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'degenerating', 'concept_id': 'C0011164', 'confidence': 1.0}, {'entity': 'vacuoles', 'concept_id': 'C0042219', 'confidence': 1.0}], [{'entity': 'Chemotherapy', 'concept_id': 'C0013216', 'confidence': 1.0}, {'entity': 'colitis', 'concept_id': 'C0009319', 'confidence': 1.0}, {'entity': 'inflammatory bowel disease', 'concept_id': 'C0021390', 'confidence': 1.0}], [{'entity': 'Mild', 'concept_id': 'C1513302', 'confidence': 1.0}, {'entity': 'degree', 'concept_id': 'C0441889', 'confidence': 1.0}, {'entity': 'architectural distortion', 'concept_id': 'C2826609', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_670",
"caption_rating": "7"
},
{
"": "1007672",
"caption": "The lining epithelium of the mature cystic teratoma is stratified squamous epithelium with skin adnexa such as sebaceous and sweat glands.",
"image_path": "3mRB9j0eyVM_image_052d39e2-dd4d-40e9-9cd4-224a3eaaec61.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gynecologic', 'Hematopathology', 'Soft tissue']",
"roi_text": "['Cheesy sebaceous material surrounding the cyst.', 'Stratified squamous epithelium lining of the mature cystic teratoma.']",
"noisy_text": " material that is cheesy sebaceous material that is surrounding this cyst. So this is a typical gross picture of a dermoid cyst or the cystic teratoma, mature cystic teratoma of the ovary. This is the histological picture of this mature cystic teratoma. The lining epithelium is stratified squamous epithelium along with the skin adenexa that are the sebaceous glands and the sweat glands. So this is all about the mature cystic. Then the germ cell tumors, malignant germ cell tumors, these are rare. 3% of the ovarian cancers are malignant germ cell tumors.",
"corrected_text": " material that is cheesy sebaceous material that is surrounding this cyst. So this is a typical gross picture of a dermoid cyst or the cystic teratoma, mature cystic teratoma of the ovary. This is the histological picture of this mature cystic teratoma. The lining epithelium is stratified squamous epithelium along with the skin adnexa that are the sebaceous glands and the sweat glands. So this is all about the mature cystic. Then the germ cell tumors, malignant germ cell tumors, these are rare. 30% of the ovarian cancers are malignant germ cell tumors.",
"med_umls_ids": "[[{'entity': 'material', 'concept_id': 'C0520510', 'confidence': 1.0}, {'entity': 'cyst', 'concept_id': 'C0010709', 'confidence': 1.0}, {'entity': 'cheesy', 'concept_id': 'C0423381', 'confidence': 0.7845876812934875}, {'entity': 'sebaceous material', 'concept_id': 'C0221947', 'confidence': 0.7280718088150024}, {'entity': 'dermoid cyst', 'concept_id': 'C0011649', 'confidence': 1.0}, {'entity': 'mature', 'concept_id': 'C0205286', 'confidence': 1.0}, {'entity': 'cystic teratoma', 'concept_id': 'C0011649', 'confidence': 0.9999998807907104}, {'entity': 'ovary', 'concept_id': 'C0029939', 'confidence': 1.0}], [{'entity': 'lining', 'concept_id': 'C0205132', 'confidence': 1.0}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'mature', 'concept_id': 'C0205286', 'confidence': 1.0}, {'entity': 'cystic teratoma', 'concept_id': 'C0011649', 'confidence': 0.9999998807907104}, {'entity': 'stratified', 'concept_id': 'C0205363', 'confidence': 1.0}, {'entity': 'squamous epithelium', 'concept_id': 'C0221909', 'confidence': 1.0}, {'entity': 'skin adnexa', 'concept_id': 'C0001575', 'confidence': 0.8680230379104614}, {'entity': 'sebaceous', 'concept_id': 'C0221947', 'confidence': 0.8709007501602173}, {'entity': 'sweat glands', 'concept_id': 'C0038989', 'confidence': 1.0}], [{'entity': 'Malignant germ cell tumors', 'concept_id': 'C4048549', 'confidence': 0.9233970046043396}, {'entity': 'rare', 'concept_id': 'C0521114', 'confidence': 1.0}, {'entity': 'ovarian cancers', 'concept_id': 'C1140680', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "960.0",
"id": "test_671",
"caption_rating": "9"
},
{
"": "1006659",
"caption": "The neuroblastoma-like variant of schwannoma can be confused with low-grade fibromyxoid sarcoma, but can be differentiated by S100 staining. Schwannoma is a benign tumor with a small round blue cell appearance.",
"image_path": "QDb68_G1HR4_image_5d5befad-1fd0-4a79-913a-f6bd875ddb25.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Schwannoma', 'neuroblastoma-like variant of schwannoma', 'low-grade fibromyxoid sarcoma', 'S100 staining', 'Schwannoma']",
"noisy_text": " people get that confused with the neuroblastoma-like variant of schwannoma and the difference is important because the schwannoma is even though the name sounds kind of scary is actually benign it has a small round blue cell appearance but it's totally benign variation of schwannoma. S100 should easily solve that problem because S100 would be negative here in low-grade fibromyxoid sarcoma and positive in the schwannoma so just important to recognize that that's one other tumor that can have collagen rosettes like that are kind of like this. There is",
"corrected_text": " people get that confused with the neuroblastoma-like variant of schwannoma and the difference is important because the schwannoma is even though the name sounds kind of scary is actually benign it has a small round blue cell appearance but it's totally benign variation of schwannoma. S100 should easily solve that problem because S100 would be negative here in low-grade fibromyxoid sarcoma and positive in the schwannoma so just important to recognize that that's one other tumor that can have collagen rosettes like that are kind of like this. There is",
"med_umls_ids": "[[{'entity': 'neuroblastoma-like variant', 'concept_id': 'C1419295', 'confidence': 0.6672105193138123}, {'entity': 'schwannoma', 'concept_id': 'C0027809', 'confidence': 0.9999998807907104}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'differentiated', 'concept_id': 'C0007589', 'confidence': 1.0}, {'entity': 'S100 staining', 'concept_id': 'C0487602', 'confidence': 0.6653134822845459}, {'entity': 'Schwannoma', 'concept_id': 'C0027809', 'confidence': 0.9999998807907104}, {'entity': 'benign tumor', 'concept_id': 'C0086692', 'confidence': 1.0}, {'entity': 'round blue cell', 'concept_id': 'C0487470', 'confidence': 0.7703027129173279}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_672",
"caption_rating": "8"
},
{
"": "1008195",
"caption": "The lesion is a small benign papule with dilated blood vessels and proliferating sebaceous lobules. It has two components: a fibrous component and an epithelial component, which includes an epithelial sebaceous gland.",
"image_path": "LlPaENuqzVQ_image_af7719ff-5684-4e3e-a43c-d9d7216a2548.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['dilated blood vessels', 'sebaceous lobules', 'fibrous component', 'epithelial component', 'epithelial sebaceous gland', 'teensy small follicle', 'dilated blood vessels', 'sebaceous lobules', 'fibrous component', 'epithelial component', 'epithelial sebaceous gland', 'teensy small follicle']",
"noisy_text": " And then there's some dilated blood vessels and whatnot, background sebaceous lobules that are proliferating. This may be kind of an incipient one of them, but this is what we're looking at here. So it's a small teensy tiny papule. And it's, if it's a neoplasm, it's got a two components to it. It's got a fibrous component, like right here. And then it's also got this epithelial component. What do you think this, what kind of differentiation are we looking at right here? Right, I feel it, right. So this is epithelial sebaceous gland. That's epithelium, little teensy small follicle right there. What's this? Is it closer to this or this? Sorry. Like, it",
"corrected_text": " And then there's some dilated blood vessels and whatnot, background sebaceous lobules that are proliferating. This may be kind of an incipient one of them, but this is what we're looking at here. So it's a small teensy tiny papule. And it's, if it's a neoplasm, it's got a two components to it. It's got a fibrous component, like right here. And then it's also got this epithelial component. What do you think this, what kind of differentiation are we looking at right here? Right, I feel it, right. So this is epithelial sebaceous gland. That's epithelium, little teensy small follicle right there. What's this? Is it closer to this or this? Sorry. Like, it",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'benign papule', 'concept_id': 'C0205183', 'confidence': 0.7019047737121582}, {'entity': 'dilated blood vessels', 'concept_id': 'C0424830', 'confidence': 1.0}, {'entity': 'proliferating sebaceous lobules', 'concept_id': 'C0221946', 'confidence': 0.7654090523719788}, {'entity': 'components', 'concept_id': 'C0449432', 'confidence': 1.0}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}, {'entity': 'epithelial component', 'concept_id': 'C1707933', 'confidence': 0.8783122897148132}, {'entity': 'epithelial sebaceous gland', 'concept_id': 'C0036505', 'confidence': 0.7906183004379272}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_673",
"caption_rating": "9"
},
{
"": "1008301",
"caption": "Sebaceomas are usually small, round, and skin-colored.",
"image_path": "udoW6VSqsm4_image_d54daff7-58ee-4355-9487-59b5c47f6572.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['sebaceoma', 'basal cell carcinoma', 'sebaceous differentiation']",
"noisy_text": " I think we've called it sebaceous epithelium, but again I'm not a big fan of that term. And these look usually like this. They're usually small, round, skin-colored leaves. They kind of look like sebaceous epithelium. They usually come in as real-life basins, so nobody diagnoses these clinically correctly. So these are items in the differential diagnosis. Basal cell with sebaceous differentiation, if you're going to make that diagnosis, it generally needs to look like a basal cell with nice clefting and put the palisade in there and all that, and then have foci where there's obvious sebaceous differentiation. You'll see that on occasion. But I would probably call this sebaceoma, without thinking it's sort of synonymous with sebaceous epithelium. Now, is there any condition you have to worry about with these? With any",
"corrected_text": " I think we've called it sebaceous epithelium, but again I'm not a big fan of that term. And these look usually like this. They're usually small, round, skin-colored leaves. They kind of look like sebaceous epithelium. They usually come in as real-life basins, so nobody diagnoses these clinically correctly. So these are items in the differential diagnosis. Basal cell with sebaceous differentiation, if you're going to make that diagnosis, it generally needs to look like a basal cell with nice clefting and put the palisade in there and all that, and then have foci where there's obvious sebaceous differentiation. You'll see that on occasion. But I would probably call this sebaceoma, without thinking it's sort of synonymous with sebaceous epithelium. Now, is there any condition you have to worry about with these? With any",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'sebaceoma', 'concept_id': 'C1275210', 'confidence': 1.0}, {'entity': 'basal cell carcinoma', 'concept_id': 'C0007117', 'confidence': 1.0}, {'entity': 'sebaceous differentiation', 'concept_id': 'C1882988', 'confidence': 1.0}], [{'entity': 'Sebaceomas', 'concept_id': 'C1275210', 'confidence': 0.8855459690093994}, {'entity': 'small', 'concept_id': 'C0700321', 'confidence': 0.9999998807907104}, {'entity': 'round', 'concept_id': 'C0332490', 'confidence': 1.0}, {'entity': 'skin-colored', 'concept_id': 'C4476819', 'confidence': 0.8005288243293762}], [{'entity': 'Basal cell carcinoma', 'concept_id': 'C0007117', 'confidence': 1.0}, {'entity': 'sebaceous differentiation', 'concept_id': 'C1882988', 'confidence': 1.0}, {'entity': 'clefting', 'concept_id': 'C4021813', 'confidence': 0.8906428217887878}, {'entity': 'palisading', 'concept_id': 'C1622240', 'confidence': 0.8684062361717224}, {'entity': 'sebaceous differentiation', 'concept_id': 'C1882988', 'confidence': 1.0}], [{'entity': 'conditions', 'concept_id': 'C0012634', 'confidence': 0.8556983470916748}, {'entity': 'concern', 'concept_id': 'C2699424', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_674",
"caption_rating": "7"
},
{
"": "1006221",
"caption": "Endothelial cells are enlarged and plump.",
"image_path": "8S4LeiO6Bbk_image_b3ec906b-b05a-40da-9d74-1e3853522bce.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['papillary projections', 'extravasated erythrocytes', 'dilated vessels', 'enlarged endothelial cells', 'collagen bundles', 'pre-existing vascular spaces', 'papillary projections', 'extravasated erythrocytes', 'dilated vessels', 'enlarged endothelial cells', 'collagen bundles', 'pre-existing vascular spaces']",
"noisy_text": " into the limina. If you look around, you can see these papillary projections. There are a few extravasated erythrocytes present within the stroma. So clearly, we've got this vascular neoplasma here with these dilated endothelial line spaces, but it's got kind of a bifasic pattern. Centrally, we've got these dilated vessels, but peripheral and beneath that zone, the vessels are somewhat more compressed. They're still lined by some of the plump endothelial cells. And in these various where the vessels are compressed, they kind of appear to dissect between collagen bundles. We even have a little bit of a promontory sign here where we've got these vessels surrounding pre-existing vascular spaces. But unlike the neovascular spaces that we see in Kaposi's sarcoma, the endothelial cells here are a little more plump, and we don't have plasma cells within the infiltrate. And plasma cells within the infiltrate can be very useful in discriminating between this condition and Kaposi's sarcoma. In this particular case, also the HHV8 stain was a negative, which",
"corrected_text": " into the limina. If you look around, you can see these papillary projections. There are a few extravasated erythrocytes present within the stroma. So clearly, we've got this vascular neoplasm here with these dilated endothelial line spaces, but it's got kind of a biphasic pattern. Centrally, we've got these dilated vessels, but peripheral and beneath that zone, the vessels are somewhat more compressed. They're still lined by some of the enlarged endothelial cells. And in these various where the vessels are compressed, they kind of appear to dissect between collagen bundles. We even have a little bit of a promontory sign here where we've got these vessels surrounding pre-existing vascular spaces. But unlike the neovascularization that we see in Kaposi's sarcoma, the endothelial cells here are a little more plump, and we don't have plasma cells within the infiltrate. And plasma cells within the infiltrate can be very useful in discriminating between this condition and Kaposi's sarcoma. In this particular case, also the HHV8 stain was a negative, which",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'vascular neoplasm', 'concept_id': 'C0027668', 'confidence': 1.0}, {'entity': 'dilated endothelial line spaces', 'concept_id': 'C0014257', 'confidence': 0.6450937390327454}, {'entity': 'biphasic pattern', 'concept_id': 'C1332555', 'confidence': 1.0}], [{'entity': 'Vessels', 'concept_id': 'C0005847', 'confidence': 1.0}, {'entity': 'peripheral', 'concept_id': 'C0205100', 'confidence': 1.0}, {'entity': 'central zone', 'concept_id': 'C0458698', 'confidence': 1.0}], [{'entity': 'Endothelial cells', 'concept_id': 'C0225336', 'confidence': 1.0}, {'entity': 'enlarged', 'concept_id': 'C0442800', 'confidence': 1.0}, {'entity': 'plump', 'concept_id': 'C1836543', 'confidence': 0.7694027423858643}], [{'entity': 'Absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'differentiate', 'concept_id': 'C0205615', 'confidence': 0.9999998807907104}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'Kaposi sarcoma', 'concept_id': 'C0036220', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "758.0",
"width": "1920.0",
"id": "test_675",
"caption_rating": "7"
},
{
"": "1005931",
"caption": "Lesions that stain with CD34 and are strongly positive for D240 are probably of lymphatic origin rather than vascular origin.",
"image_path": "8S4LeiO6Bbk_image_d45f4a7f-f27c-459c-980a-d6d5bc542879.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['dilated vascular channels', 'papillary projections', 'enlarged endothelial cells', 'compressed vascular channels', 'extravasated erythrocytes', 'dilated vascular channels', 'papillary projections', 'enlarged endothelial cells', 'compressed vascular channels', 'extravasated erythrocytes']",
"noisy_text": " which will slowly risk halt. These lesions will stain, frequently with CD34, but also are strongly positive for D240. So they probably are of lymphatic origin rather than vascular origin. What one looks for is a biphasic vascular tumor with this central area characterized by these dilated vascular channels. Let's look at the bottom piece, which frequently do contain these papillary projections, which protrude into the lumina, these plump endothelial cells, and then at the periphery, more compressed vascular channels, which dissect between collagen bundles. And it's at the periphery one frequently sees extravasated erythrocytes, siderophages, and",
"corrected_text": " which will slowly risk halt. These lesions will stain, frequently with CD34, but also are strongly positive for D240. So they probably are of lymphatic origin rather than vascular origin. What one looks for is a biphasic vascular tumor with this central area characterized by these dilated vascular channels. Let's look at the bottom piece, which frequently do contain these papillary projections, which protrude into the lumina, these plump endothelial cells, and then at the periphery, more compressed vascular channels, which dissect between collagen bundles. And it's at the periphery one frequently sees extravasated erythrocytes, siderophages, and",
"med_umls_ids": "[[{'entity': 'Lesions', 'concept_id': 'C0221198', 'confidence': 1.0}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'CD34', 'concept_id': 'C0054953', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'D240', 'concept_id': 'C3766973', 'confidence': 0.5323090553283691}, {'entity': 'lymphatic origin', 'concept_id': 'C0229889', 'confidence': 0.7706887125968933}, {'entity': 'vascular origin', 'concept_id': 'C0395959', 'confidence': 0.7819716334342957}], [{'entity': 'biphasic', 'concept_id': 'C0205184', 'confidence': 1.0}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'dilated', 'concept_id': 'C0700124', 'confidence': 0.9999999403953552}, {'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}, {'entity': 'central area', 'concept_id': 'C0929543', 'confidence': 0.8492603302001953}], [{'entity': 'Papillary projections', 'concept_id': 'C0016538', 'confidence': 0.7451471090316772}, {'entity': 'bottom piece', 'concept_id': 'C1511276', 'confidence': 0.722324788570404}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}], [{'entity': 'Enlarged endothelial cells', 'concept_id': 'C0423263', 'confidence': 0.7785332202911377}, {'entity': 'papillary projections', 'concept_id': 'C0016538', 'confidence': 0.7451471090316772}], [{'entity': 'Compressed vascular channels', 'concept_id': 'C1336948', 'confidence': 0.5993747711181641}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}], [{'entity': 'Extravasated', 'concept_id': 'C0015376', 'confidence': 0.868863582611084}, {'entity': 'erythrocytes', 'concept_id': 'C0014772', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_676",
"caption_rating": "9"
},
{
"": "1007247",
"caption": "Low-grade fibromyxoid sarcomas with swirling growth can mimic perineuriomas and often express Clodin-1.",
"image_path": "QDb68_G1HR4_image_7807ddd7-4e7e-4a1d-aeba-2e2b021c55bc.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Deep soft tissue', 'Perineurioma', 'Low-grade fibromyxoid sarcoma', 'Immunohistochemistry', 'Swirling growth']",
"noisy_text": " involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is more of a difficult problem because perineurioma has a lot of overlap histologically with low-grade fibromyxoid sarcoma and also immunohistochemically. On immunostains, EMA, Clodin-1 and Glut-1 are three immunostains that will usually stain perineuriomas. The problem is that low-grade fibromyxoid sarcomas often express at least focal EMA, so that's a problem and additionally, the examples of low-grade fibromyxoid sarcoma that have dramatic swirling and whirling growth, those are the ones that have a perineurioma like pattern, the ones that mimic perineurioma. They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The",
"corrected_text": " involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is more of a difficult problem because perineurioma has a lot of overlap histologically with low-grade fibromyxoid sarcoma and also immunohistochemically. On immunostains, EMA, Clodin-1 and Glut-1 are three immunostains that will usually stain perineuriomas. The problem is that low-grade fibromyxoid sarcomas often express at least focal EMA, so that's a problem and additionally, the examples of low-grade fibromyxoid sarcoma that have dramatic swirling and whirling growth, those are the ones that have a perineurioma like pattern, the ones that mimic perineurioma. They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The",
"med_umls_ids": "[[{'entity': 'CD34', 'concept_id': 'C0054953', 'confidence': 1.0}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'deep soft tissue tumors', 'concept_id': 'C0037579', 'confidence': 0.8622524738311768}], [{'entity': 'Perineurioma', 'concept_id': 'C0751691', 'confidence': 0.9999999403953552}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'histologically', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'immunohistochemistry', 'concept_id': 'C0021044', 'confidence': 0.9999998807907104}], [{'entity': 'EMA', 'concept_id': 'C0268596', 'confidence': 0.9999999403953552}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}, {'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'immunohistochemical stains', 'concept_id': 'C4317108', 'confidence': 0.9999999403953552}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibrosarcomas', 'concept_id': 'C0016057', 'confidence': 1.0}, {'entity': 'EMA', 'concept_id': 'C0268596', 'confidence': 0.9999999403953552}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}], [{'entity': 'Low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'swirling', 'concept_id': 'C0233591', 'confidence': 0.7064549922943115}, {'entity': 'growth', 'concept_id': 'C0018270', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'express', 'concept_id': 'C0017262', 'confidence': 0.8176293969154358}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}], [{'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'reports', 'concept_id': 'C0684224', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcomas', 'concept_id': 'C1275282', 'confidence': 0.8123146891593933}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_677",
"caption_rating": "9"
},
{
"": "1008334",
"caption": "Pseudomembranes can be caused by Clostridioides difficile colitis or ischemic injury.",
"image_path": "sDFjOtMAYrk_image_c349f8b8-d567-4ceb-abc0-085ad1d06be2.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['lamina propria', 'pseudomembranes', 'ischemia', 'C. diff', 'lamina propria', 'pseudomembranes', 'ischemia', 'C. diff']",
"noisy_text": " will give you pseudomembranes. Ischemic injury can also give it to you. And the one thing to note is that, so this patient had C. difficile colitis by laboratory, but he was not responding to treatment and they just decided to take a biopsy. And you can see here that in the lamina propria is not hyalinized. Now, does that mean that ischemia is excluded? No, because if it's, you know, it depends on the clinical history. If it's recent ischemia that happened within, I don't know, 24, 48 hours, you know, the hyalinopropia may not have had time to hyalinize. How long does it take for the lamina propria to become pink? I don't know, but longer. So C. diff. Oh, another mimic of ischemia. And you can see why this mimics ischemia. The lamina propria is kind of pink and hyalinized. On top of that, there's actually some architectural distortion. This",
"corrected_text": " will give you pseudomembranes. Ischemic injury can also give it to you. And the one thing to note is that, so this patient had Clostridioides difficile colitis by laboratory, but he was not responding to treatment and they just decided to take a biopsy. And you can see here that in the lamina propria is not hyalinized. Now, does that mean that ischemia is excluded? No, because if it's, you know, it depends on the clinical history. If it's recent ischemia that happened within, I don't know, 24, 48 hours, you know, the hyalinopropia may not have had time to hyalinize. How long does it take for the lamina propria to become pink? I don't know, but longer. So C. diff. Oh, another mimic of ischemia. And you can see why this mimics ischemia. The lamina propria is kind of pink and hyalinized. On top of that, there's actually some architectural distortion. This",
"med_umls_ids": "[[{'entity': 'Pseudomembranes', 'concept_id': 'C0240821', 'confidence': 1.0}, {'entity': 'Clostridioides', 'concept_id': 'C4406271', 'confidence': 1.0}, {'entity': 'colitis', 'concept_id': 'C0009319', 'confidence': 1.0}, {'entity': 'ischemic injury', 'concept_id': 'C2945681', 'confidence': 0.8915668725967407}], [{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'hyalinized', 'concept_id': 'C0332230', 'confidence': 1.0}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}, {'entity': 'excluded', 'concept_id': 'C0332196', 'confidence': 1.0}], [{'entity': 'C. diff', 'concept_id': 'C0238106', 'confidence': 0.8398770093917847}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}, {'entity': 'pink', 'concept_id': 'C0332585', 'confidence': 1.0}, {'entity': 'hyalinized lamina propria', 'concept_id': 'C0332230', 'confidence': 0.7577076554298401}, {'entity': 'architectural changes', 'concept_id': 'C0003737', 'confidence': 0.7067119479179382}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_678",
"caption_rating": "8"
},
{
"": "1008717",
"caption": "The nuclei of the stratified cells reach the middle third and maintain polarity, with no prominent nuclei or cribriform/micropapillary formation.",
"image_path": "r7OA0Trj5hQ_image_ba0204fe-74f3-4de7-883a-70f79613c8aa.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Nuclei traveling in one direction', 'Stratified nuclei reaching middle third', 'Nuclei traveling in one direction', 'Maintained polarity', 'No prominent nuclei', 'No cribriform/micropapillary formation']",
"noisy_text": " And this stratified nuclei reach the middle third. They are not touching the upper top of the apical membrane. They are reaching the middle third predominantly. Okay, that is one important point. And other one is, look at this nuclei. They are all traveling in one direction. So the polarity is maintained. Okay, so those two points are very important. And the third one is no prominent nuclei. Nuclei are not prominent. And the fourth point is, no cribriformic or micropapillary formation. So the predominant features you see here is the maintained polarity, nuclei reaching",
"corrected_text": " And this stratified nuclei reach the middle third. They are not touching the upper top of the apical membrane. They are reaching the middle third predominantly. Okay, that is one important point. And other one is, look at this nuclei. They are all traveling in one direction. So the polarity is maintained. Okay, so those two points are very important. And the third one is no prominent nuclei. Nuclei are not prominent. And the fourth point is, no cribriform pattern or micropapillary formation. So the predominant features you see here is the maintained polarity, nuclei reaching",
"med_umls_ids": "[[{'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'stratified cells', 'concept_id': 'C0205363', 'confidence': 0.7615563869476318}, {'entity': 'middle', 'concept_id': 'C0227972', 'confidence': 1.0}, {'entity': 'polarity', 'concept_id': 'C0596963', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'cribriform/micropapillary formation', 'concept_id': 'C1621425', 'confidence': 0.5390191674232483}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_679",
"caption_rating": "9"
},
{
"": "1005846",
"caption": "Lymphoid follicles are abnormal in the stomach and seen in chronic gastroenteritis.",
"image_path": "r7OA0Trj5hQ_image_13d38800-3698-413a-b008-820a0a473b9d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Granulomas in the lamina propria', 'Lymphoid follicles in the stomach', 'Cytoplasmic inclusions', 'Lymphoid follicles in the stomach']",
"noisy_text": " So this is chronic colitis with activity. These are granulomas in the lamina propria. Think of tuberculosis in India, sarcoidosis, fungal infections, or idiopathic, or foreign bodies. So those are all the four main things. Any granuloma, infectious or non-infectious. When infectious, is it necrotizing or non-necrotizing? Lymphoid follicles, again, abnormal in the stomach. And they are seen in the lamina propria, chronic gastroenteritis. You can all identify these beautiful inclusions. And some cytoplasmic inclusions also, nuclear and",
"corrected_text": " So this is chronic colitis with activity. These are granulomas in the lamina propria. Think of tuberculosis in India, sarcoidosis, fungal infections, or idiopathic, or foreign bodies. So those are all the four main things. Any granuloma, infectious or non-infectious. When infectious, is it necrotizing or non-necrotizing? Lymphoid follicles, again, abnormal in the stomach. And they are seen in the lamina propria, chronic gastroenteritis. You can all identify these beautiful inclusions. And some cytoplasmic inclusions also, nuclear and",
"med_umls_ids": "[[{'entity': 'Chronic colitis', 'concept_id': 'C0267375', 'confidence': 0.9999999403953552}, {'entity': 'activity', 'concept_id': 'C0026606', 'confidence': 1.0}, {'entity': 'granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}], [{'entity': 'Granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}, {'entity': 'tuberculosis', 'concept_id': 'C0041296', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'fungal infections', 'concept_id': 'C0026946', 'confidence': 1.0}, {'entity': 'idiopathic', 'concept_id': 'C0332240', 'confidence': 0.9999998807907104}, {'entity': 'foreign bodies', 'concept_id': 'C0016542', 'confidence': 1.0}], [{'entity': 'Lymphoid follicles', 'concept_id': 'C0229654', 'confidence': 0.9380706548690796}, {'entity': 'abnormal', 'concept_id': 'C0205161', 'confidence': 1.0}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'chronic gastroenteritis', 'concept_id': 'C0017160', 'confidence': 0.8353270292282104}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_680",
"caption_rating": "7"
},
{
"": "1006016",
"caption": "Neurotropism and microcystic adnexal carcinoma commonly involve nerves.",
"image_path": "LlPaENuqzVQ_image_2beb252a-0e73-4aee-92e8-acad841e9e79.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['Lesion dissecting throughout the dermis', 'No nerve involvement observed', 'Sclerosing epithelial neoplasms', 'Deep biopsy necessary for definitive diagnosis']",
"noisy_text": " So this thing is kind of dissecting diffusely throughout the dermis here. I don't see any nerve involvement in this case but it's very common to get neurotropism and microcystic anexal carcinoma. So I'm not gonna belabor the differential diagnosis of the sclerosing epithelial neoplasms but you need to know that. And you need to know that you need to take a good deep biopsy in order to make a definitive diagnosis or you won't get a definitive diagnosis. And there's no stain that helps. Everybody says, oh, you can do a T63 or this and the other, looking for Merkel cells or CK20. I've never found any of these things to be helpful. And the other differential that sometimes comes up is the",
"corrected_text": " So this thing is kind of dissecting diffusely throughout the dermis here. I don't see any nerve involvement in this case but it's very common to get neurotropism and microcystic adnexal carcinoma. So I'm not gonna belabor the differential diagnosis of the sclerosing epithelial neoplasms but you need to know that. And you need to know that you need to take a good deep biopsy in order to make a definitive diagnosis or you won't get a definitive diagnosis. And there's no stain that helps. Everybody says, oh, you can do a T63 or this and the other, looking for Merkel cells or CK20. I've never found any of these things to be helpful. And the other differential that sometimes comes up is the",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'diffusely', 'concept_id': 'C0205219', 'confidence': 0.8011853098869324}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}], [{'entity': 'Neurotropism', 'concept_id': 'C1518304', 'confidence': 1.0}, {'entity': 'microcystic adnexal carcinoma', 'concept_id': 'C0346027', 'confidence': 1.0}, {'entity': 'nerves', 'concept_id': 'C0027740', 'confidence': 1.0}], [{'entity': 'deep biopsy', 'concept_id': 'C0185285', 'confidence': 0.8188310265541077}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'sclerosing', 'concept_id': 'C0036426', 'confidence': 0.833010733127594}, {'entity': 'epithelial neoplasms', 'concept_id': 'C1368683', 'confidence': 0.9999999403953552}], [{'entity': 'No stain', 'concept_id': 'C0038128', 'confidence': 0.8399802446365356}, {'entity': 'diagnosing', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'sclerosing', 'concept_id': 'C0036426', 'confidence': 0.833010733127594}, {'entity': 'epithelial neoplasms', 'concept_id': 'C1368683', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_681",
"caption_rating": "8"
},
{
"": "1004527",
"caption": "The patient had a history of uveitis with characteristic features of sarcoidosis.",
"image_path": "sDFjOtMAYrk_image_e0950091-4fb6-4609-8e92-4dbb4c12c9f0.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['granuloma', 'lamina propria', 'Crohn\u2019s disease', 'infectious process', 'sarcoidosis', 'uveitis']",
"noisy_text": " I like this place. So if you have big coalescing masses of granuloma, expanding your lamina propria, think something other than Crohn's. Think of infectious process, especially if they're necrotizing, but even if they're not, and also think of sarcoid. This patient had sarcoid. So I said, this is probably not IBD, clinicians came down, we want to look at the biopsy, of course. It turns out that they went back and talked to the patient. The patient has a history of uveitis with characteristic features that were good for sarcoidosis. Nobody knew about they treated the patient for sarcoid, re-biopsied the patient. And he was fine. There were no more granulomas on multiple repeat biopsies. And now compare those grannies with the grannies in Crohn's. So here's",
"corrected_text": " I like this place. So if you have big coalescing masses of granuloma, expanding your lamina propria, think something other than Crohn's. Think of infectious process, especially if they're necrotizing, but even if they're not, and also think of sarcoid. This patient had sarcoid. So I said, this is probably not IBD, clinicians came down, we want to look at the biopsy, of course. It turns out that they went back and talked to the patient. The patient has a history of uveitis with characteristic features that were good for sarcoidosis. Nobody knew about they treated the patient for sarcoid, re-biopsied the patient. And he was fine. There were no more granulomas on multiple repeat biopsies. And now compare those grannies with the grannies in Crohn's. So here's",
"med_umls_ids": "[[{'entity': 'Coalescing masses', 'concept_id': 'C4727092', 'confidence': 0.5960795283317566}, {'entity': 'granuloma', 'concept_id': 'C0018188', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'infectious process', 'concept_id': 'C0745283', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'Crohn\u2019s disease', 'concept_id': 'C0010346', 'confidence': 0.8916962146759033}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'history', 'concept_id': 'C0019664', 'confidence': 1.0}, {'entity': 'uveitis', 'concept_id': 'C0042164', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}], [{'entity': 'Re-biopsy', 'concept_id': 'C0005558', 'confidence': 0.6681398749351501}, {'entity': 'granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}, {'entity': 'treatment', 'concept_id': 'C0039798', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_682",
"caption_rating": "7"
},
{
"": "1009099",
"caption": "The patient is a solid organ transplant recipient with mycophenol-associated injury, which typically has more eosinophils than GVHD.",
"image_path": "sDFjOtMAYrk_image_fdc63c33-230e-490f-9844-45f92c696e15.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['pyloric gland metaplasia', 'solid organ transplant recipient', 'eosinophils', 'pyloric gland metaplasia', 'solid organ transplant recipient', 'eosinophils']",
"noisy_text": " Yeah, these cells, these glands right here. What is it? Yeah, exactly. It's a pyloric glomeruloplasia. So pyloric glomeruloplasia should be Crohn's. No, you can see pyloric glomeruloplasia in your sort of a colitis and end-associated injury and also in microphenol-associated injury, as this case is. And the tip of the patient is a solid organ transplant recipient. with microphenol-associated injury have many more in the way of eosinophils, a lot more in the way of eosinophils than GVHD patients do. So that's really, really helpful. Is there",
"corrected_text": " Yeah, these cells, these glands right here. What is it? Yeah, exactly. It's a pyloric gland metaplasia. So pyloric gland metaplasia should be Crohn's. No, you can see pyloric gland metaplasia in your sort of a colitis and end-associated injury and also in mycophenol-associated injury, as this case is. And the tip of the patient is a solid organ transplant recipient. with mycophenol-associated injury have many more in the way of eosinophils, a lot more in the way of eosinophils than GVHD patients do. So that's really, really helpful. Is there",
"med_umls_ids": "[[{'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'image', 'concept_id': 'C1696103', 'confidence': 1.0}, {'entity': 'pyloric gland metaplasia', 'concept_id': 'C4288813', 'confidence': 1.0}, {'entity': 'colitis', 'concept_id': 'C0009319', 'confidence': 1.0}, {'entity': 'end-associated injury', 'concept_id': 'C0552509', 'confidence': 0.6716579794883728}, {'entity': 'mycophenol-associated injury', 'concept_id': 'C0552509', 'confidence': 0.6023857593536377}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'solid organ transplant', 'concept_id': 'C0730400', 'confidence': 1.0}, {'entity': 'recipient', 'concept_id': 'C1709854', 'confidence': 1.0}, {'entity': 'mycophenol-associated injury', 'concept_id': 'C0552509', 'confidence': 0.6023857593536377}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'GVHD', 'concept_id': 'C0018133', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_683",
"caption_rating": "8"
},
{
"": "1008110",
"caption": "Negative MUC4 stain suggests cellular intramuscular myxoma.",
"image_path": "QDb68_G1HR4_image_3fd48468-516d-41b7-b65c-1e2b8862f938.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " And on a needle biopsy I think that can be challenging. So I think usually with some experience you can tell them apart on H and E most of the time but when I have any doubt I just do a MUC4 stain. The MUC4 is negative and on a needle it looks like a myxoma with some kind of fibrous or a little bit more cellular areas and then I just say that it's probably a cellular intramuscular myxoma. So I think MUC4 is a really helpful stain and if you don't have it in your lab you can send out and get it done at outside labs too. So again when you have the whole tumor removed it's pretty easy to tell that this is not an intramuscular myxoma. Intramuscular myxoma",
"corrected_text": " And on a needle biopsy I think that can be challenging. So I think usually with some experience you can tell them apart on H and E most of the time but when I have any doubt I just do a MUC4 stain. The MUC4 is negative and on a needle it looks like a myxoma with some kind of fibrous or a little bit more cellular areas and then I just say that it's probably a cellular intramuscular myxoma. So I think MUC4 is a really helpful stain and if you don't have it in your lab you can send out and get it done at outside labs too. So again when you have the whole tumor removed it's pretty easy to tell that this is not an intramuscular myxoma. Intramuscular myxoma",
"med_umls_ids": "[[{'entity': 'Differentiating', 'concept_id': 'C0205615', 'confidence': 1.0}, {'entity': 'myxoma', 'concept_id': 'C0027149', 'confidence': 1.0}, {'entity': 'cellular intramuscular myxoma', 'concept_id': 'C1334260', 'confidence': 0.8910117149353027}, {'entity': 'needle biopsy', 'concept_id': 'C0005560', 'confidence': 1.0}], [{'entity': 'MUC4', 'concept_id': 'C1417496', 'confidence': 0.9999999403953552}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}], [{'entity': 'Negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'MUC4', 'concept_id': 'C1417496', 'confidence': 0.9999999403953552}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'cellular intramuscular myxoma', 'concept_id': 'C1334260', 'confidence': 0.8910117149353027}], [{'entity': 'Complete', 'concept_id': 'C0205197', 'confidence': 0.9999998807907104}, {'entity': 'differentiate', 'concept_id': 'C0205615', 'confidence': 0.9999998807907104}, {'entity': 'myxoma', 'concept_id': 'C0027149', 'confidence': 1.0}, {'entity': 'cellular intramuscular myxoma', 'concept_id': 'C1334260', 'confidence': 0.8910117149353027}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_684",
"caption_rating": "8"
},
{
"": "1006437",
"caption": "Description of translocation sarcoma in myxoid liposarcoma, with FUS-DDIT3 being the most common translocation.",
"image_path": "pBR26SS0FX8_image_c1d5f272-fea4-4df3-ad6a-3a2d34ca509d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Hematopathology', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " in regular conventional myxoid liposarcoma. You see these little cells, they are also very bland. Again, a translocation sarcoma, right? So these cells have a translocation. FUSDDIT3 used to be called FUSCHOP, was the most common one. Occasionally a subset of them like 5% or so will have EWSR1, Ewing's gene rearranged with DDIT3. And so if you haven't learned yet that a lot of times if there's a rearrangement of EWSR1 with some other gene, eventually someone's gonna find cases that have FUS rearranged with that same gene and vice versa because FUS and EWSR1 are similar genes, a kind of same gene family, which again, this is way over my head, I'm not a molecular pathologist. But the point is they often swap out for one another. So that's",
"corrected_text": " in regular conventional myxoid liposarcoma. You see these little cells, they are also very bland. Again, a translocation sarcoma, right? So these cells have a translocation. FUS-DDIT3 used to be called FUSCHOP, was the most common one. Occasionally a subset of them like 5% or so will have EWSR1, Ewing's gene rearranged with DDIT3. And so if you haven't learned yet that a lot of times if there's a rearrangement of EWSR1 with some other gene, eventually someone's gonna find cases that have FUS rearranged with that same gene and vice versa because FUS and EWSR1 are similar genes, a kind of same gene family, which again, this is way over my head, I'm not a molecular pathologist. But the point is they often swap out for one another. So that's",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'translocation sarcoma', 'concept_id': 'C0040715', 'confidence': 0.7855618000030518}, {'entity': 'myxoid liposarcoma', 'concept_id': 'C0206634', 'confidence': 1.0}, {'entity': 'FUS-DDIT3', 'concept_id': 'C1852061', 'confidence': 0.894819438457489}, {'entity': 'translocation', 'concept_id': 'C0040715', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_685",
"caption_rating": "8"
},
{
"": "1008111",
"caption": "Complete tumor removal makes it easy to differentiate between myxoma and cellular intramuscular myxoma.",
"image_path": "QDb68_G1HR4_image_3fd48468-516d-41b7-b65c-1e2b8862f938.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " And on a needle biopsy I think that can be challenging. So I think usually with some experience you can tell them apart on H and E most of the time but when I have any doubt I just do a MUC4 stain. The MUC4 is negative and on a needle it looks like a myxoma with some kind of fibrous or a little bit more cellular areas and then I just say that it's probably a cellular intramuscular myxoma. So I think MUC4 is a really helpful stain and if you don't have it in your lab you can send out and get it done at outside labs too. So again when you have the whole tumor removed it's pretty easy to tell that this is not an intramuscular myxoma. Intramuscular myxoma",
"corrected_text": " And on a needle biopsy I think that can be challenging. So I think usually with some experience you can tell them apart on H and E most of the time but when I have any doubt I just do a MUC4 stain. The MUC4 is negative and on a needle it looks like a myxoma with some kind of fibrous or a little bit more cellular areas and then I just say that it's probably a cellular intramuscular myxoma. So I think MUC4 is a really helpful stain and if you don't have it in your lab you can send out and get it done at outside labs too. So again when you have the whole tumor removed it's pretty easy to tell that this is not an intramuscular myxoma. Intramuscular myxoma",
"med_umls_ids": "[[{'entity': 'Differentiating', 'concept_id': 'C0205615', 'confidence': 1.0}, {'entity': 'myxoma', 'concept_id': 'C0027149', 'confidence': 1.0}, {'entity': 'cellular intramuscular myxoma', 'concept_id': 'C1334260', 'confidence': 0.8910117149353027}, {'entity': 'needle biopsy', 'concept_id': 'C0005560', 'confidence': 1.0}], [{'entity': 'MUC4', 'concept_id': 'C1417496', 'confidence': 0.9999999403953552}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}], [{'entity': 'Negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'MUC4', 'concept_id': 'C1417496', 'confidence': 0.9999999403953552}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'cellular intramuscular myxoma', 'concept_id': 'C1334260', 'confidence': 0.8910117149353027}], [{'entity': 'Complete', 'concept_id': 'C0205197', 'confidence': 0.9999998807907104}, {'entity': 'differentiate', 'concept_id': 'C0205615', 'confidence': 0.9999998807907104}, {'entity': 'myxoma', 'concept_id': 'C0027149', 'confidence': 1.0}, {'entity': 'cellular intramuscular myxoma', 'concept_id': 'C1334260', 'confidence': 0.8910117149353027}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_686",
"caption_rating": "8"
},
{
"": "1006968",
"caption": "Vessels are compressed in peripheral and beneath the central zone.",
"image_path": "8S4LeiO6Bbk_image_f42e1c55-b1f3-439b-8bfc-72791c93176b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['papillary projections', 'extravasated erythrocytes', 'dilated vessels', 'enlarged endothelial cells', 'collagen bundles', 'pre-existing vascular spaces', 'papillary projections', 'extravasated erythrocytes', 'dilated vessels', 'enlarged endothelial cells', 'collagen bundles', 'pre-existing vascular spaces']",
"noisy_text": " into the limina. If you look around, you can see these papillary projections. There are a few extravasated erythrocytes present within the stroma. So clearly, we've got this vascular neoplasma here with these dilated endothelial line spaces, but it's got kind of a bifasic pattern. Centrally, we've got these dilated vessels, but peripheral and beneath that zone, the vessels are somewhat more compressed. They're still lined by some of the plump endothelial cells. And in these various where the vessels are compressed, they kind of appear to dissect between collagen bundles. We even have a little bit of a promontory sign here where we've got these vessels surrounding pre-existing vascular spaces. But unlike the neovascular spaces that we see in Kaposi's sarcoma, the endothelial cells here are a little more plump, and we don't have plasma cells within the infiltrate. And plasma cells within the infiltrate can be very useful in discriminating between this condition and Kaposi's sarcoma. In this particular case, also the HHV8 stain was a negative, which",
"corrected_text": " into the limina. If you look around, you can see these papillary projections. There are a few extravasated erythrocytes present within the stroma. So clearly, we've got this vascular neoplasm here with these dilated endothelial line spaces, but it's got kind of a biphasic pattern. Centrally, we've got these dilated vessels, but peripheral and beneath that zone, the vessels are somewhat more compressed. They're still lined by some of the enlarged endothelial cells. And in these various where the vessels are compressed, they kind of appear to dissect between collagen bundles. We even have a little bit of a promontory sign here where we've got these vessels surrounding pre-existing vascular spaces. But unlike the neovascularization that we see in Kaposi's sarcoma, the endothelial cells here are a little more plump, and we don't have plasma cells within the infiltrate. And plasma cells within the infiltrate can be very useful in discriminating between this condition and Kaposi's sarcoma. In this particular case, also the HHV8 stain was a negative, which",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'vascular neoplasm', 'concept_id': 'C0027668', 'confidence': 1.0}, {'entity': 'dilated endothelial line spaces', 'concept_id': 'C0014257', 'confidence': 0.6450937390327454}, {'entity': 'biphasic pattern', 'concept_id': 'C1332555', 'confidence': 1.0}], [{'entity': 'Vessels', 'concept_id': 'C0005847', 'confidence': 1.0}, {'entity': 'peripheral', 'concept_id': 'C0205100', 'confidence': 1.0}, {'entity': 'central zone', 'concept_id': 'C0458698', 'confidence': 1.0}], [{'entity': 'Endothelial cells', 'concept_id': 'C0225336', 'confidence': 1.0}, {'entity': 'enlarged', 'concept_id': 'C0442800', 'confidence': 1.0}, {'entity': 'plump', 'concept_id': 'C1836543', 'confidence': 0.7694027423858643}], [{'entity': 'Absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'differentiate', 'concept_id': 'C0205615', 'confidence': 0.9999998807907104}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'Kaposi sarcoma', 'concept_id': 'C0036220', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "758.0",
"width": "1920.0",
"id": "test_687",
"caption_rating": "7"
},
{
"": "1004666",
"caption": "The patient had a positive digital rectal examination and elevated PSA level.",
"image_path": "iklRyY1nBIE_image_a46f7ff7-e57e-4483-9fa1-fa24f07a41d7.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['teratoma component', 'prostate', 'bladder', 'positive digital rectal examination', 'elevated PSA level']",
"noisy_text": " tumor, got therapy, and unfortunately, had the teratoma. And this happens a lot. The therapy took care of the other embryonic, carcinoma, yolk cell tumor components, semi-normal components, et cetera, but the teratoma component stayed behind. So this is the margin that is always negative. As you can see, there is tumor present. So the teratoma extended to this area also. So this was a diffuse involvement of the prostate. There was also some bladder involvement by this tumor. So this was bad news for this gentleman. So the last case I'm going to share before we go to the Q&A is case number 10. Case number 10 is a 58-year-old gentleman with a positive digital rectal examination and elevated PSA level. So right off the bat, you can appreciate that this is an",
"corrected_text": " tumor, got therapy, and unfortunately, had the teratoma. And this happens a lot. The therapy took care of the other embryonic, carcinoma, yolk cell tumor components, normal components, et cetera, but the teratoma component stayed behind. So this is the margin that is always negative. As you can see, there is tumor present. So the teratoma extended to this area also. So this was a diffuse involvement of the prostate. There was also some bladder involvement by this tumor. So this was bad news for this gentleman. So the last case I'm going to share before we go to the Q&A is case number 10. Case number 10 is a 58-year-old gentleman with a positive digital rectal examination and elevated PSA level. So right off the bat, you can appreciate that this is an",
"med_umls_ids": "[[{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'teratoma', 'concept_id': 'C0039538', 'confidence': 1.0}, {'entity': 'component', 'concept_id': 'C0449432', 'confidence': 1.0}, {'entity': 'therapy', 'concept_id': 'C0039798', 'confidence': 0.9999999403953552}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'bladder', 'concept_id': 'C0005682', 'confidence': 1.0}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'digital rectal examination', 'concept_id': 'C0199900', 'confidence': 1.0}, {'entity': 'elevated', 'concept_id': 'C0205250', 'confidence': 0.9999999403953552}, {'entity': 'PSA', 'concept_id': 'C0138741', 'confidence': 1.0}, {'entity': 'level', 'concept_id': 'C0441889', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_688",
"caption_rating": "7"
},
{
"": "1006026",
"caption": "Papillary projections are frequently seen in the bottom piece of the tumor.",
"image_path": "8S4LeiO6Bbk_image_aa903496-ae7f-4150-9b54-0225f8d20fbe.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['dilated vascular channels', 'papillary projections', 'enlarged endothelial cells', 'compressed vascular channels', 'extravasated erythrocytes']",
"noisy_text": " which will slowly risk halt. These lesions will stain, frequently with CD34, but also are strongly positive for D240. So they probably are of lymphatic origin rather than vascular origin. What one looks for is a biphasic vascular tumor with this central area characterized by these dilated vascular channels. Let's look at the bottom piece, which frequently do contain these papillary projections, which protrude into the lumina, these plump endothelial cells, and then at the periphery, more compressed vascular channels, which dissect between collagen bundles. And it's at the periphery one frequently sees extravasated erythrocytes, siderophages, and",
"corrected_text": " which will slowly risk halt. These lesions will stain, frequently with CD34, but also are strongly positive for D240. So they probably are of lymphatic origin rather than vascular origin. What one looks for is a biphasic vascular tumor with this central area characterized by these dilated vascular channels. Let's look at the bottom piece, which frequently do contain these papillary projections, which protrude into the lumina, these plump endothelial cells, and then at the periphery, more compressed vascular channels, which dissect between collagen bundles. And it's at the periphery one frequently sees extravasated erythrocytes, siderophages, and",
"med_umls_ids": "[[{'entity': 'Lesions', 'concept_id': 'C0221198', 'confidence': 1.0}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'CD34', 'concept_id': 'C0054953', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'D240', 'concept_id': 'C3766973', 'confidence': 0.5323090553283691}, {'entity': 'lymphatic origin', 'concept_id': 'C0229889', 'confidence': 0.7706887125968933}, {'entity': 'vascular origin', 'concept_id': 'C0395959', 'confidence': 0.7819716334342957}], [{'entity': 'biphasic', 'concept_id': 'C0205184', 'confidence': 1.0}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'dilated', 'concept_id': 'C0700124', 'confidence': 0.9999999403953552}, {'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}, {'entity': 'central area', 'concept_id': 'C0929543', 'confidence': 0.8492603302001953}], [{'entity': 'Papillary projections', 'concept_id': 'C0016538', 'confidence': 0.7451471090316772}, {'entity': 'bottom piece', 'concept_id': 'C1511276', 'confidence': 0.722324788570404}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}], [{'entity': 'Enlarged endothelial cells', 'concept_id': 'C0423263', 'confidence': 0.7785332202911377}, {'entity': 'papillary projections', 'concept_id': 'C0016538', 'confidence': 0.7451471090316772}], [{'entity': 'Compressed vascular channels', 'concept_id': 'C1336948', 'confidence': 0.5993747711181641}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}], [{'entity': 'Extravasated', 'concept_id': 'C0015376', 'confidence': 0.868863582611084}, {'entity': 'erythrocytes', 'concept_id': 'C0014772', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_689",
"caption_rating": "7"
},
{
"": "1006879",
"caption": "Rare cases of cysts may have a high-grade pleomorphic sarcoma appearance or even osteosarcomatous areas.",
"image_path": "QDb68_G1HR4_image_2d07ce43-7c97-4d79-8e95-3a4f9f1d4f2a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " There have also been rare reports of cases that truly have a full-blown high-grade pleomorphic sarcoma like appearance like that they've transitioned into high-grade sarcoma or I think even osteosarcomatous areas have been described. These are all really rare exceptions to the rule but I and I think it's again much more important for the general pathologists to know that this very bland benign looking appearance because this is the one that's going to be easy to misdiagnose and diagnose it as something benign when it's actually malignant. So again here look at the alternation more cellular stuff less cellular stuff very helpful to see this kind of zonation in swirling intermingling of more and less cellular areas of pink fibrous areas and",
"corrected_text": " There have also been rare reports of cases that truly have a full-blown high-grade pleomorphic sarcoma like appearance like that they've transitioned into high-grade sarcoma or I think even osteosarcomatous areas have been described have been described. These are all really rare exceptions to the rule but I and I think it's again much more important for the general pathologists to know that this very bland benign looking appearance because this is the one that's going to be easy to misdiagnose and diagnose it as something benign when it's actually malignant. So again here look at the alternation more cellular stuff less cellular stuff very helpful to see this kind of zonation in swirling intermingling of more and less cellular areas of pink fibrous areas and",
"med_umls_ids": "[[{'entity': 'Rare', 'concept_id': 'C0521114', 'confidence': 1.0}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'cysts', 'concept_id': 'C0010709', 'confidence': 1.0}, {'entity': 'high-grade', 'concept_id': 'C1512433', 'confidence': 0.9347730875015259}, {'entity': 'pleomorphic sarcoma', 'concept_id': 'C1261358', 'confidence': 0.9260651469230652}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'osteosarcomatous areas', 'concept_id': 'C0279602', 'confidence': 0.7822340130805969}], [{'entity': 'pathologists', 'concept_id': 'C0334866', 'confidence': 1.0}, {'entity': 'benign', 'concept_id': 'C0205183', 'confidence': 1.0}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'cysts', 'concept_id': 'C0010709', 'confidence': 1.0}, {'entity': 'misdiagnosed', 'concept_id': 'C0679838', 'confidence': 0.896425724029541}, {'entity': 'malignant', 'concept_id': 'C0205282', 'confidence': 1.0}], [{'entity': 'Zonation', 'concept_id': 'C0019360', 'confidence': 0.7375882267951965}, {'entity': 'cellular areas', 'concept_id': 'C0007634', 'confidence': 0.7882957458496094}, {'entity': 'pink fibrous', 'concept_id': 'C0439709', 'confidence': 0.7378140091896057}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_690",
"caption_rating": "8"
},
{
"": "1006904",
"caption": "Ectatic vessels are present in the papillary dermis with pallor consistent with edema and perivascular infiltrate of lymphocytes.",
"image_path": "hoV-JkD6Wb0_image_76a7e23e-ea5d-4876-81e3-95755ad3101d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['ectatic vessels', 'papillary dermis', 'perivascular infiltrate of lymphocytes', 'collections of immune cells', 'narrow cuff of mononuclear cells', 'ectatic vessels', 'papillary dermis', 'perivascular infiltrate of lymphocytes', 'collections of immune cells', 'narrow cuff of mononuclear cells']",
"noisy_text": " and we'll take a look at two of them, you had to review similar findings, bisected punch. And as expected, there are ectatic vessels here. Let me tilt the slide here. And the papillary dermis, a little bit of pallor consistent with edema, a little bit of a perivascular infiltrate of lymphocytes. And then present throughout the dermis, there are a few collections of epithelioid histiocytes. Here, there's one right there. And down here, we have another collection of epithelioid histiocytes. These are surrounded by a narrow cuff of mononuclear cells, but many",
"corrected_text": " and we'll take a look at two of them, you had to review similar findings, bisected punch. And as expected, there are ectatic vessels here. Let me tilt the slide here. And the papillary dermis, a little bit of pallor consistent with edema, a little bit of a perivascular infiltrate of lymphocytes. And then present throughout the dermis, there are a few collections of epithelioid histiocytes. Here, there's one right there. And down here, we have another collection of epithelioid histiocytes. These are surrounded by a narrow cuff of mononuclear cells, but many",
"med_umls_ids": "[[{'entity': 'Ectatic vessels', 'concept_id': 'C0005847', 'confidence': 0.7720959186553955}, {'entity': 'papillary dermis', 'concept_id': 'C0682598', 'confidence': 1.0}, {'entity': 'pallor', 'concept_id': 'C0030232', 'confidence': 1.0}, {'entity': 'consistent with', 'concept_id': 'C0332290', 'confidence': 1.0}, {'entity': 'edema', 'concept_id': 'C0013604', 'confidence': 0.9999999403953552}, {'entity': 'perivascular', 'concept_id': 'C0442165', 'confidence': 1.0}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}], [{'entity': 'Collections', 'concept_id': 'C0600644', 'confidence': 0.8663196563720703}, {'entity': 'immune cells', 'concept_id': 'C4330475', 'confidence': 0.8268961906433105}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'surrounded', 'concept_id': 'C1282914', 'confidence': 1.0}, {'entity': 'cuff', 'concept_id': 'C0441107', 'confidence': 1.0}, {'entity': 'mononuclear cells', 'concept_id': 'C0806987', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_691",
"caption_rating": "10"
},
{
"": "1004591",
"caption": "Melanin granules within melanophages are more uniform in size and shape compared to hemosiderin pigment in centroblasts.",
"image_path": "8S4LeiO6Bbk_image_9667fa36-5fd9-4553-9f8c-8b3cdac2b6c1.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Melanin granules within melanophages', 'Extravasated erythrocytes', 'Increased melanin in the basilar keratinocytes.', 'Melanin granules within melanophages', 'Extravasated erythrocytes', 'Increased melanin in the basilar keratinocytes.']",
"noisy_text": " or the melanophages is variable in size and shape. Now look at the melanin granules within this melanophage, and you can see that they're much more uniform in size and shape. Now look at the melanin granules within this melanophage, and you can see that they're much more uniform in size than the hemocentauric pigment in the centaurifages. It also tends to be a little bit darker staining, but sometimes it can be very difficult, tinctorially, depending upon the staining quality, to use color to distinguish the two, better to use size and context clues. Also note here we don't have any extravasated erythrocytes here, so much more likely to be melanin, and there's an increased melanin in the basilar keratinocytes. Getting back to the case, thin epidermis, bacular",
"corrected_text": " or the melanophages is variable in size and shape. Now look at the melanin granules within this melanophage, and you can see that they're much more uniform in size and shape. Now look at the melanin granules within this melanophage, and you can see that they're much more uniform in size than the hemosiderin pigment in the centroblasts. It also tends to be a little bit darker staining, but sometimes it can be very difficult, tinctorially, depending upon the staining quality, to use color to distinguish the two, better to use size and context clues. Also note here we don't have any extravasated erythrocytes here, so much more likely to be melanin, and there's an increased melanin in the basilar keratinocytes. Getting back to the case, thin epidermis, bacular",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'melanophages', 'concept_id': 'C3280463', 'confidence': 0.9375340938568115}, {'entity': 'variable size', 'concept_id': 'C1866144', 'confidence': 0.8559831976890564}, {'entity': 'shape', 'concept_id': 'C0332479', 'confidence': 1.0}], [{'entity': 'Melanin granules', 'concept_id': 'C0230692', 'confidence': 0.9174172878265381}, {'entity': 'melanophages', 'concept_id': 'C3280463', 'confidence': 0.9375340938568115}, {'entity': 'uniform', 'concept_id': 'C0205375', 'confidence': 1.0}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'shape', 'concept_id': 'C0332479', 'confidence': 1.0}, {'entity': 'hemosiderin', 'concept_id': 'C0019113', 'confidence': 1.0}, {'entity': 'pigment', 'concept_id': 'C0031911', 'confidence': 1.0}, {'entity': 'centroblasts', 'concept_id': 'C1517735', 'confidence': 0.8281925320625305}], [{'entity': 'Increased', 'concept_id': 'C0205217', 'confidence': 1.0}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}, {'entity': 'basilar keratinocytes', 'concept_id': 'C0022567', 'confidence': 0.803361713886261}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_692",
"caption_rating": "8"
},
{
"": "1009220",
"caption": "Involvement around damaged nerves is a common feature of sarcoid granulomatous inflammation.",
"image_path": "udoW6VSqsm4_image_45ba8961-111e-440a-bff9-00b87992409c.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['sarcoid granulomatous inflammation', 'involvement around nerves']",
"noisy_text": " That's the tuberculoid. Yeah, good. The tuberculoid form of leprosy gives you sarcoidal granulomatous inflammation. It's elongated. Very good. That's exactly right. What else can give you sarcoidal granulomatous inflammation? Can I ask a quick question about the sarcoid with the two... The nansins? So, I had a case, I saw a case that looked kind of horizontal, but it was sarcoid. And so, what other ways can you tell? Sometimes it can be difficult, but usually you're going to see involvement around nerves damaged nerves. You're about to get sarcoidal granulomatous inflammation. They always have very high risk inflammatory reactions. They just wipe out the nerves. So, that's helpful. Wasn't",
"corrected_text": " That's the tuberculoid. Yeah, good. The tuberculoid form of leprosy gives you sarcoidal granulomatous inflammation. It's elongated. Very good. That's exactly right. What else can give you sarcoidal granulomatous inflammation? Can I ask a quick question about the sarcoid with the two... The sarcoidosis? So, I had a case, I saw a case that looked kind of horizontal, but it was sarcoid. And so, what other ways can you tell? Sometimes it can be difficult, but usually you're going to see involvement around nerves damaged nerves. You're about to get sarcoidal granulomatous inflammation. They always have very high risk inflammatory reactions. They just wipe out the nerves. So, that's helpful. Wasn't",
"med_umls_ids": "[[{'entity': 'Tuberculoid', 'concept_id': 'C0544783', 'confidence': 0.8459237217903137}, {'entity': 'leprosy', 'concept_id': 'C0023343', 'confidence': 1.0}, {'entity': 'sarcoid', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'granulomatous inflammation', 'concept_id': 'C0553697', 'confidence': 1.0}], [{'entity': 'Involvement', 'concept_id': 'C1314939', 'confidence': 1.0}, {'entity': 'damaged nerves', 'concept_id': 'C3887709', 'confidence': 0.8087002038955688}, {'entity': 'sarcoid', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'granulomatous inflammation', 'concept_id': 'C0553697', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_693",
"caption_rating": "8"
},
{
"": "1006422",
"caption": "Severe dysplasia seen in resection.",
"image_path": "r7OA0Trj5hQ_image_997a8219-edca-40e9-b1e8-2aa60d52f990.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Severe dysplasia', 'Thick and thin blood vessels', 'Thick vessel wall', 'Narrowing of lumen', 'Vein and artery identification', 'No internal elastic lamina', 'Vein and artery identification', 'Severe dysplasia', 'Thick and thin blood vessels', 'Thick vessel wall', 'Narrowing of lumen', 'Vein and artery identification', 'No internal elastic lamina']",
"noisy_text": " And in the resection, you see like a heavy malformation, isn't it? Thick and thin blood vessels of varying sizes are seen. In high power, you can see very thick vessel wall with the narrowing of the lumen, whereas here, it is relatively preserved. So you want to know whether it is a vein or artery. Please believe me, this is a vein, and this is an artery. And that is proved by the elastic tissue strain. These are all pictures from Dr. Gonzalez's Twitter. And you can see here, there is no internal elastic lamina, whereas here,",
"corrected_text": " And in the resection, you see like a heavy malformation, isn't it? Thick and thin blood vessels of varying sizes are seen. In high power, you can see very thick vessel wall with the narrowing of the lumen, whereas here, it is relatively preserved. So you want to know whether it is a vein or artery. Please believe me, this is a vein, and this is an artery. And that is proved by the elastic tissue strain. These are all pictures from Dr. Gonzalez's Twitter. And you can see here, there is no internal elastic lamina, whereas here,",
"med_umls_ids": "[[{'entity': 'Severe', 'concept_id': 'C0205082', 'confidence': 1.0}, {'entity': 'resection', 'concept_id': 'C0015252', 'confidence': 1.0}], [{'entity': 'Thick', 'concept_id': 'C1280412', 'confidence': 1.0}, {'entity': 'thin', 'concept_id': 'C0205168', 'confidence': 1.0}, {'entity': 'sizes', 'concept_id': 'C0456389', 'confidence': 1.0}], [{'entity': 'Thick vessel wall', 'concept_id': 'C1180033', 'confidence': 0.6420797109603882}, {'entity': 'narrowing', 'concept_id': 'C0332463', 'confidence': 1.0}, {'entity': 'lumen', 'concept_id': 'C0524461', 'confidence': 0.9999998807907104}, {'entity': 'power', 'concept_id': 'C0032863', 'confidence': 1.0}], [{'entity': 'Identification', 'concept_id': 'C0020792', 'confidence': 1.0}, {'entity': 'vein', 'concept_id': 'C0042449', 'confidence': 1.0}, {'entity': 'artery', 'concept_id': 'C0003842', 'confidence': 1.0}, {'entity': 'elastic tissue', 'concept_id': 'C0013762', 'confidence': 1.0}, {'entity': 'strain', 'concept_id': 'C0080194', 'confidence': 1.0}], [{'entity': 'image', 'concept_id': 'C1696103', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_694",
"caption_rating": "7"
},
{
"": "1008177",
"caption": "Arabesque-type fibular material seen at the periphery of the fat microcysts.",
"image_path": "hoV-JkD6Wb0_image_4a527a05-1434-4bf5-a26a-6d9a6454057f.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['Large fat microcysts', 'Membranous lipodystrophy at the periphery of the fat microcysts', 'Arabesque-type fibular material at the periphery of the fat microcysts', 'Remnant cell walls of adipocytes at the periphery of the fat microcysts', 'Large fat microcysts', 'Membranous lipodystrophy at the periphery of the fat microcysts', 'Arabesque-type fibular material at the periphery of the fat microcysts', 'Remnant cell walls of adipocytes at the periphery of the fat microcysts']",
"noisy_text": " inflammation. There aren't many viable adipocytes left here. A lot of the adipocytes have kind of ruptured and fused, and so we've got these large fat microcysts, and if we look at the periphery of the fat microcyst, we've got this lipomembranous change, this kind of arabesque-type fibular material out at the periphery, which basically represents coalescence of remnant cell walls of adipocytes. In addition, within the surrounding tissue, there's a little bit of fibrosis. There are a few lipophages and a very sparse infiltrative",
"corrected_text": " inflammation. There aren't many viable adipocytes left here. A lot of the adipocytes have kind of ruptured and fused, and so we've got these large fat microcysts, and if we look at the periphery of the fat microcyst, we've got this lipomembranous change, this kind of arabesque-type fibular material out at the periphery, which basically represents coalescence of remnant cell walls of adipocytes. In addition, within the surrounding tissue, there's a little bit of fibrosis. There are a few lipophages and a very sparse infiltrative",
"med_umls_ids": "[[{'entity': 'Inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}], [{'entity': 'adipocytes', 'concept_id': 'C0206131', 'confidence': 1.0}, {'entity': 'left', 'concept_id': 'C0205091', 'confidence': 1.0}], [{'entity': 'fat microcysts', 'concept_id': 'C1513269', 'confidence': 0.871767520904541}], [{'entity': 'Membranous lipodystrophy', 'concept_id': 'C0406599', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'fat microcysts', 'concept_id': 'C1513269', 'confidence': 0.871767520904541}], [{'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'fat microcysts', 'concept_id': 'C1513269', 'confidence': 0.871767520904541}], [{'entity': 'Coalescence', 'concept_id': 'C4727092', 'confidence': 0.8749340176582336}, {'entity': 'remnant', 'concept_id': 'C3272697', 'confidence': 1.0}, {'entity': 'cell walls', 'concept_id': 'C0007623', 'confidence': 1.0}, {'entity': 'adipocytes', 'concept_id': 'C0206131', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'fat microcysts', 'concept_id': 'C1513269', 'confidence': 0.871767520904541}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_695",
"caption_rating": "7"
},
{
"": "1008208",
"caption": "Involvement around damaged nerves is a common feature of sarcoid granulomatous inflammation.",
"image_path": "udoW6VSqsm4_image_6d531ab3-9793-4f54-aa26-8e480f237723.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['sarcoid granulomatous inflammation', 'involvement around nerves']",
"noisy_text": " That's the tuberculoid. Yeah, good. The tuberculoid form of leprosy gives you sarcoidal granulomatous inflammation. It's elongated. Very good. That's exactly right. What else can give you sarcoidal granulomatous inflammation? Can I ask a quick question about the sarcoid with the two... The nansins? So, I had a case, I saw a case that looked kind of horizontal, but it was sarcoid. And so, what other ways can you tell? Sometimes it can be difficult, but usually you're going to see involvement around nerves damaged nerves. You're about to get sarcoidal granulomatous inflammation. They always have very high risk inflammatory reactions. They just wipe out the nerves. So, that's helpful. Wasn't",
"corrected_text": " That's the tuberculoid. Yeah, good. The tuberculoid form of leprosy gives you sarcoidal granulomatous inflammation. It's elongated. Very good. That's exactly right. What else can give you sarcoidal granulomatous inflammation? Can I ask a quick question about the sarcoid with the two... The sarcoidosis? So, I had a case, I saw a case that looked kind of horizontal, but it was sarcoid. And so, what other ways can you tell? Sometimes it can be difficult, but usually you're going to see involvement around nerves damaged nerves. You're about to get sarcoidal granulomatous inflammation. They always have very high risk inflammatory reactions. They just wipe out the nerves. So, that's helpful. Wasn't",
"med_umls_ids": "[[{'entity': 'Tuberculoid', 'concept_id': 'C0544783', 'confidence': 0.8459237217903137}, {'entity': 'leprosy', 'concept_id': 'C0023343', 'confidence': 1.0}, {'entity': 'sarcoid', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'granulomatous inflammation', 'concept_id': 'C0553697', 'confidence': 1.0}], [{'entity': 'Involvement', 'concept_id': 'C1314939', 'confidence': 1.0}, {'entity': 'damaged nerves', 'concept_id': 'C3887709', 'confidence': 0.8087002038955688}, {'entity': 'sarcoid', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'granulomatous inflammation', 'concept_id': 'C0553697', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_696",
"caption_rating": "8"
},
{
"": "1008939",
"caption": "Special stains such as Prussian blue or Fontana-Masson can be used to confirm the presence of hemocyanin or melanin pigment.",
"image_path": "8S4LeiO6Bbk_image_cc7d42e4-f76c-4df4-843a-cf0b51945268.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Pigmented histiocytes with hemocyanin pigment', 'Extravasated erythrocytes', 'Size of particles within histiocytes', 'Size of particles within histiocytes']",
"noisy_text": " in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes as suspected is hemocentaurant. If you notice, it's got kind of that golden brown color. If you had a sub-stage condenser or a fine focus knob, you would see that it's somewhat refractile, but unfortunately, we can't use that particular tool when we're looking at scanned images. But one clue to the fact that we're dealing with hemocentaurant rather than melanin, not only is the presence of extravasated erythrocytes, but if you look at the size of the particles within the histiocytes, they're markedly variable. So the hemocentaurant is of course a breakdown product of the RBCs. And you can see that we've got small granules next to very large, chunky granules. Melanin pigment on the other hand, which of course can be found in melanophages or histiocytes containing the particles, the melanin granules tend to be more uniform in size. And of course, one can always do special stains, an iron stain, such as Prussian blue or pearls for hemocentaurant and a Fontanumus song stain for melanin pigment. So in any case, getting back to the to the lesion in question, we've got a lot of hemocentaurant-laden histiocytes here. We've also got, in other areas, fascicles, kind of randomly oriented of histiocytes and fibrocytes with oval",
"corrected_text": " in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes as suspected is hemocyanin. If you notice, it's got kind of that golden brown color. If you had a sub-stage condenser or a fine focus knob, you would see that it's somewhat refractile, but unfortunately, we can't use that particular tool when we're looking at scanned images. But one clue to the fact that we're dealing with hemocyanin rather than melanin, not only is the presence of extravasated erythrocytes, but if you look at the size of the particles within the histiocytes, they're markedly variable. So the hemocyanin is of course a breakdown product of the RBCs. And you can see that we've got small granules next to very large, chunky granules. Melanin pigment on the other hand, which of course can be found in melanophages or histiocytes containing the particles, the melanin granules tend to be more uniform in size. And of course, one can always do special stains, an iron stain, such as Prussian blue or pearls for hemocyanin and a Fontana-Masson stain for melanin pigment. So in any case, getting back to the to the lesion in question, we've got a lot of hemocyanin-laden histiocytes here. We've also got, in other areas, fascicles, kind of randomly oriented of histiocytes and fibrocytes with oval",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'pigment', 'concept_id': 'C0031911', 'confidence': 1.0}, {'entity': 'breakdown', 'concept_id': 'C0699900', 'confidence': 0.9999999403953552}, {'entity': 'product', 'concept_id': 'C1254351', 'confidence': 1.0}, {'entity': 'RBCs', 'concept_id': 'C0014792', 'confidence': 1.0}], [{'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'particles', 'concept_id': 'C0597177', 'confidence': 1.0}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'variable', 'concept_id': 'C0439828', 'confidence': 1.0}], [{'entity': 'Melanin', 'concept_id': 'C0025196', 'confidence': 1.0}, {'entity': 'pigment', 'concept_id': 'C0031911', 'confidence': 1.0}, {'entity': 'uniform', 'concept_id': 'C0205375', 'confidence': 1.0}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}], [{'entity': 'Special stains', 'concept_id': 'C0038128', 'confidence': 0.7105166912078857}, {'entity': 'Prussian blue', 'concept_id': 'C0060234', 'confidence': 1.0}, {'entity': 'Fontana-Masson', 'concept_id': 'C0060631', 'confidence': 0.9090515375137329}, {'entity': 'confirm', 'concept_id': 'C0521093', 'confidence': 1.0}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}, {'entity': 'pigment', 'concept_id': 'C0031911', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_697",
"caption_rating": "8"
},
{
"": "1004212",
"caption": "The presence of numerous melanocytes in the matrix layer is highly suspicious for melanoma in situ.",
"image_path": "8S4LeiO6Bbk_image_5f174254-0490-4295-ae0c-e926e4473247.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['nail bed', 'matrix epithelium', 'melanocytes forming nests', 'pagetoid pattern', 'basal layer of the matrix', 'upper portions of the matrix']",
"noisy_text": " we've got nail bed and matricle epithelium. I believe this must be some nail fold, a portion of the nail fold, and then in the bottom piece of tissue in these sections we actually have matricle epithelium and you can see the rete or somewhat hyperplastic. And on higher power examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matricle epithelium in the matricle layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that",
"corrected_text": " we've got nail bed and matrix epithelium. I believe this must be some nail fold, a portion of the nail fold, and then in the bottom piece of tissue in these sections we actually have matrix epithelium and you can see the rete or somewhat hyperplastic. And on higher power examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matrix epithelium in the matrix layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that",
"med_umls_ids": "[[{'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'nail', 'concept_id': 'C0027342', 'confidence': 1.0}, {'entity': 'matrix epithelium', 'concept_id': 'C0014609', 'confidence': 0.7584323883056641}], [{'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'nests', 'concept_id': 'C0035253', 'confidence': 0.7275967001914978}, {'entity': 'upper portions', 'concept_id': 'C0449719', 'confidence': 0.6251541972160339}, {'entity': 'matrix', 'concept_id': 'C0331858', 'confidence': 1.0}, {'entity': 'pagetoid', 'concept_id': 'C1518847', 'confidence': 0.8801172375679016}, {'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}], [{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'matrix layer', 'concept_id': 'C0331858', 'confidence': 0.71736741065979}, {'entity': 'suspicious', 'concept_id': 'C0750493', 'confidence': 1.0}, {'entity': 'melanoma', 'concept_id': 'C0025202', 'confidence': 1.0}, {'entity': 'in situ', 'concept_id': 'C0444498', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_698",
"caption_rating": "9"
},
{
"": "1005937",
"caption": "The patient has massive exfoliative dermatitis, which is a condition characterized by widespread scaling and flaking of the skin.",
"image_path": "udoW6VSqsm4_image_0970f7df-4263-4a2e-b1ee-98b576574175.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['Exfoliative dermatitis']",
"noisy_text": " Pidicarenalysis, yeah, is that what this is? I didn't see any of this. No, this would be the piticarenalysis that ate Cleveland or something. Massive loss of the stratum corneum. It's really big. Those are usually teensy tiny little bells. So, this may not be in your vocabulary. You know, if you don't speak Russian and somebody asks you what's the Russian word for restaurant, you wouldn't know that it looked like pectopaw, you know, when you looked at it the way it was spelled. So, basically, if this isn't in your vocabulary, you don't have any idea what it is. Of course, you would notice that there's loss of the stratum corneum and there's also loss of the greater psoas. Who knows what this is? None of you guys know?",
"corrected_text": " pityriasis, yeah, is that what this is? I didn't see any of this. No, this would be the pityriasis that ate Cleveland or something. Massive loss of the stratum corneum. It's really big. Those are usually teensy tiny little bells. So, this may not be in your vocabulary. You know, if you don't speak Russian and somebody asks you what's the Russian word for restaurant, you wouldn't know that it looked like restaurant, you know, when you looked at it the way it was spelled. So, basically, if this isn't in your vocabulary, you don't have any idea what it is. Of course, you would notice that there's loss of the stratum corneum and there's also loss of the greater omentum. Who knows what this is? None of you guys know?",
"med_umls_ids": "[[{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'massive', 'concept_id': 'C0522501', 'confidence': 1.0}, {'entity': 'exfoliative dermatitis', 'concept_id': 'C0011606', 'confidence': 1.0}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'widespread', 'concept_id': 'C0205219', 'confidence': 1.0}, {'entity': 'scaling', 'concept_id': 'C0237849', 'confidence': 1.0}, {'entity': 'flaking', 'concept_id': 'C1880783', 'confidence': 1.0}, {'entity': 'skin', 'concept_id': 'C0444099', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_699",
"caption_rating": "8"
},
{
"": "1007603",
"caption": "The epidermis is slightly thinned with a basement of the reed bridge pattern.",
"image_path": "8S4LeiO6Bbk_image_8735b46d-df9d-4706-a284-4fdabb7c7d9d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Uniform spindle-shaped cells in the dermis with elongated and tapered nuclei and indistinct cytoplasmic margins', 'Thickened cornified layer', 'Slightly thinned epidermis with a basement of the reed bridge pattern', 'Uniform spindle-shaped cells in the dermis with elongated and tapered nuclei and indistinct cytoplasmic margins', 'Crisscross configuration of fascicles throughout the dermis', 'Thickened cornified layer', 'Slightly thinned epidermis with a basement of the reed bridge pattern', 'Uniform spindle-shaped cells in the dermis with elongated and tapered nuclei and indistinct cytoplasmic margins', 'Crisscross configuration of fascicles throughout the dermis']",
"noisy_text": " kind of relegated to do in this case, we can see that the cornified layer is somewhat thickened. This biopsy was from near an acral surface. This was from the finger. You can see that the epidermis is slightly thinned with the basement of the reed bridge pattern, and then filling the dermis in this case, we have fascicles of uniform spindle-shaped cells. You can see that their nuclei are elongated and tapered. The cytoplasmic margins of these cells are somewhat indistinct. They do have somewhat elongated cytoplasmic processes, and there are a range of fascicles. Some of the fascicles are cut in cross-section. Here you can see the nuclei appear more round. Some are cut longitudinally, and that's where we see the very elongated nuclei and cytoplasmic processes, and some are cut tangentially. This gives these fascicles kind of a crisscross configuration throughout the dermis. Hopefully, you all were able to pick up on the diagnostic feature in",
"corrected_text": " kind of relegated to do in this case, we can see that the cornified layer is somewhat thickened. This biopsy was from near an acral surface. This was from the finger. You can see that the epidermis is slightly thinned with the basement of the reed bridge pattern, and then filling the dermis in this case, we have fascicles of uniform spindle-shaped cells. You can see that their nuclei are elongated and tapered. The cytoplasmic margins of these cells are somewhat indistinct. They do have somewhat elongated cytoplasmic processes, and there are a range of fascicles. Some of the fascicles are cut in cross-section. Here you can see the nuclei appear more round. Some are cut longitudinally, and that's where we see the very elongated nuclei and cytoplasmic processes, and some are cut tangentially. This gives these fascicles kind of a crisscross configuration throughout the dermis. Hopefully, you all were able to pick up on the diagnostic feature in",
"med_umls_ids": "[[{'entity': 'cornified layer', 'concept_id': 'C3554359', 'confidence': 0.8562335968017578}, {'entity': 'thickened', 'concept_id': 'C0205400', 'confidence': 1.0}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}], [{'entity': 'epidermis', 'concept_id': 'C0014520', 'confidence': 1.0}, {'entity': 'thinned', 'concept_id': 'C0392758', 'confidence': 1.0}, {'entity': 'basement', 'concept_id': 'C0085872', 'confidence': 0.772655725479126}, {'entity': 'reed', 'concept_id': 'C0681191', 'confidence': 0.7412400841712952}], [{'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'fascicles', 'concept_id': 'C1185741', 'confidence': 1.0}, {'entity': 'uniform', 'concept_id': 'C0205375', 'confidence': 1.0}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}, {'entity': 'elongated', 'concept_id': 'C0205166', 'confidence': 1.0}, {'entity': 'tapered', 'concept_id': 'C0441640', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'indistinct cytoplasmic margins', 'concept_id': 'C4323148', 'confidence': 0.6683960556983948}], [{'entity': 'fascicles', 'concept_id': 'C1185741', 'confidence': 1.0}, {'entity': 'crisscross configuration', 'concept_id': 'C0449830', 'confidence': 0.7424066066741943}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_700",
"caption_rating": "7"
},
{
"": "1006728",
"caption": "Description of vessel patterns in tumors, including the arc shape seen in some tumors such as low-grade fibromyxoid sarcoma.",
"image_path": "QDb68_G1HR4_image_6ea1f4bc-7320-4141-aa1d-588cb03d1b5a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['arc-shaped vessels']",
"noisy_text": " It's not always there but it's a feature you see sometimes and the vessels kind of have this arc shape. They're kind of little curves like a little arch or a little hairpin turn like the vessel comes up and then loops and goes straight back in the direction it came. So you can see these vessels here. They're a little different than the vessels of say a mixofibrosarcoma grade one. Mixofibrosarcomas as I discussed in my other video usually have these long curving vessels. You can see vessels like that sometimes in in this tumor also in low grade fibromyxoid sarcoma but the kind of one of the classic vessel patterns is this this this arc shape, this curved",
"corrected_text": " It's not always there but it's a feature you see sometimes and the vessels kind of have this arc shape. They're kind of little curves like a little arch or a little hairpin turn like the vessel comes up and then loops and goes straight back in the direction it came. So you can see these vessels here. They're a little different than the vessels of say a myxofibrosarcoma grade one. myxofibrosarcomas as I discussed in my other video usually have these long curving vessels. You can see vessels like that sometimes in in this tumor also in low grade fibromyxoid sarcoma but the kind of one of the classic vessel patterns is this this this arc shape, this curved",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'vessel', 'concept_id': 'C0005847', 'confidence': 1.0}, {'entity': 'patterns', 'concept_id': 'C0449774', 'confidence': 1.0}, {'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'arc', 'concept_id': 'C0001857', 'confidence': 1.0}, {'entity': 'shape', 'concept_id': 'C0332479', 'confidence': 1.0}, {'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_701",
"caption_rating": "7"
},
{
"": "1004370",
"caption": "Nodules on acral skin can be caused by leukocytoclastic vasculitis that can end up with these nodular lesions.",
"image_path": "udoW6VSqsm4_image_4616f6ad-a0aa-43a0-a0ed-7b746818cd8e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " You notice this is on acral skin. There are often nodules in that area, and they can start off as palpable purpura in some cases. So, it's like, you know, regular leukocytoplastic vasculitis that can end up with these nodular lesions. Next slide. What is the histologic identical twin of this process? The granulomyphial. Yes, excellent. Granulomyphial looks very, very similar to this on the microscope. Obviously, clinically, it's not like this. It's on the face. It's on the pseudolymphoma. Next slide. So, this is a type of chronic vasculitis that ends up forming these fibrotic nodules. It's an interesting condition, and it is thought to be associated with other conditions. So, you want to make sure that you don't just, next case. A lot of times, these things can give you cholesterol clefts. One of the old names for this years ago used to be extracellular cholesterolosis, and it would give you these, all these neutrophils would gradually degranulate, if you will. The neutrophil products would have lipid in them, and you'd get these cholesterol clefts that would look kind of yellowish. Now, what are a couple other clinical diseases where you can see nodules around joints? You know, like, gout, RA, OE. Good. Gout, RA. There's",
"corrected_text": " You notice this is on acral skin. There are often nodules in that area, and they can start off as palpable purpura in some cases. So, it's like, you know, leukocytoclastic vasculitis that can end up with these nodular lesions. Next slide. What is the histologic identical twin of this process? The granuloma faciale. Yes, excellent. granuloma faciale looks very, very similar to this on the microscope. Obviously, clinically, it's not like this. It's on the face. It's on the pseudolymphoma. Next slide. So, this is a type of chronic vasculitis that ends up forming these fibrotic nodules. It's an interesting condition, and it is thought to be associated with other conditions. So, you want to make sure that you don't just, next case. A lot of times, these things can give you cholesterol clefts. One of the old names for this years ago used to be extracellular cholesterolosis, and it would give you these, all these neutrophils would gradually degranulate, if you will. The neutrophil products would have lipid in them, and you'd get these cholesterol clefts that would look kind of yellowish. Now, what are a couple other clinical diseases where you can see nodules around joints? You know, like, gout, RA, OE. Good. Gout, RA. There's",
"med_umls_ids": "[[{'entity': 'Nodules', 'concept_id': 'C0028259', 'confidence': 1.0}, {'entity': 'acral skin', 'concept_id': 'C0444099', 'confidence': 0.7122198939323425}, {'entity': 'leukocytoclastic vasculitis', 'concept_id': 'C0151436', 'confidence': 1.0}, {'entity': 'nodular', 'concept_id': 'C0205297', 'confidence': 1.0}, {'entity': 'lesions', 'concept_id': 'C0221198', 'confidence': 1.0}], [{'entity': 'Granuloma faciale', 'concept_id': 'C0239495', 'confidence': 1.0}, {'entity': 'histologic', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'identical', 'concept_id': 'C0205280', 'confidence': 1.0}, {'entity': 'twin', 'concept_id': 'C0041427', 'confidence': 0.9999999403953552}, {'entity': 'process', 'concept_id': 'C1184743', 'confidence': 1.0}], [{'entity': 'Granuloma faciale', 'concept_id': 'C0239495', 'confidence': 1.0}, {'entity': 'leukocytoclastic vasculitis', 'concept_id': 'C0151436', 'confidence': 1.0}, {'entity': 'microscope', 'concept_id': 'C0181839', 'confidence': 1.0}], [{'entity': 'Chronic vasculitis', 'concept_id': 'C0042384', 'confidence': 0.7992802858352661}, {'entity': 'fibrotic nodules', 'concept_id': 'C0332561', 'confidence': 0.8351579308509827}], [{'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'associated with', 'concept_id': 'C0332281', 'confidence': 1.0}, {'entity': 'conditions', 'concept_id': 'C0012634', 'confidence': 0.8556983470916748}], [{'entity': 'Extracellular cholesterolosis', 'concept_id': 'C2973528', 'confidence': 0.9169934391975403}, {'entity': 'cholesterol clefts', 'concept_id': 'C3686582', 'confidence': 0.9999999403953552}, {'entity': 'yellowish nodules', 'concept_id': 'C1867455', 'confidence': 0.8135299682617188}], [{'entity': 'Nodules', 'concept_id': 'C0028259', 'confidence': 1.0}, {'entity': 'joints', 'concept_id': 'C0022417', 'confidence': 1.0}, {'entity': 'gout', 'concept_id': 'C0018099', 'confidence': 1.0}, {'entity': 'RA', 'concept_id': 'C0002893', 'confidence': 1.0}, {'entity': 'OE', 'concept_id': 'C1551089', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_702",
"caption_rating": "7"
},
{
"": "1004875",
"caption": "Rare reports of cases with a full-blown high-grade pleomorphic sarcoma-like appearance or osteosarcomatous areas have been described.",
"image_path": "QDb68_G1HR4_image_b97387a8-0fda-46af-a5b8-e4828215e011.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " Now I've been telling you and highlighting how important it is to know that these tumors don't have atypia. Now again that's another rule that's sometimes broken I think it's important to learn that the most common the most common appearance is a benign looking tumor that doesn't look atypical that's important because I think that's the one those are the ones that are easy to miss but it is worth noting that a subset a small subset maybe around 10% of cases can have areas with increased cellularity, scattered pleomorphism, a round cell or epithelioid cell appearance. There have also been rare reports of cases that truly have a full-blown high-grade pleomorphic sarcoma like appearance like that they've transitioned into high-grade sarcoma or I think even osteosarcomatous areas have been described. These are all really rare exceptions to the rule but I and I think it's again much more important for the general pathologists to know that this very bland benign looking appearance because this",
"corrected_text": " Now I've been telling you and highlighting how important it is to know that these tumors don't have atypia. Now again that's another rule that's sometimes broken I think it's important to learn that the most common the most common appearance is a benign looking tumor that doesn't look atypical that's important because I think that's the one those are the ones that are easy to miss but it is worth noting that a subset a small subset maybe around 10% of cases can have areas with increased cellularity, scattered pleomorphism, a round cell or epithelioid cell appearance. There have also been rare reports of cases that truly have a full-blown high-grade pleomorphic sarcoma like appearance like that they've transitioned into high-grade sarcoma or I think even osteosarcomatous areas have been described have been described. These are all really rare exceptions to the rule but I and I think it's again much more important for the general pathologists to know that this very bland benign looking appearance because this",
"med_umls_ids": "[[{'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'benign', 'concept_id': 'C0205183', 'confidence': 1.0}, {'entity': 'atypia', 'concept_id': 'C0741302', 'confidence': 0.9999999403953552}], [{'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'increased', 'concept_id': 'C0205217', 'confidence': 1.0}, {'entity': 'cellularity', 'concept_id': 'C0178539', 'confidence': 0.9999999403953552}, {'entity': 'scattered', 'concept_id': 'C0439742', 'confidence': 1.0}, {'entity': 'pleomorphism', 'concept_id': 'C0032219', 'confidence': 1.0}, {'entity': 'round cell', 'concept_id': 'C0487470', 'confidence': 1.0}, {'entity': 'epithelioid cell', 'concept_id': 'C0014603', 'confidence': 0.9999999403953552}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}], [{'entity': 'Rare', 'concept_id': 'C0521114', 'confidence': 1.0}, {'entity': 'reports', 'concept_id': 'C0684224', 'confidence': 1.0}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'high-grade', 'concept_id': 'C1512433', 'confidence': 0.9347730875015259}, {'entity': 'pleomorphic', 'concept_id': 'C1514164', 'confidence': 1.0}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'osteosarcomatous areas', 'concept_id': 'C0279602', 'confidence': 0.7822340130805969}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_703",
"caption_rating": "8"
},
{
"": "1006025",
"caption": "A biphasic vascular tumor is characterized by dilated vascular channels in the central area.",
"image_path": "8S4LeiO6Bbk_image_aa903496-ae7f-4150-9b54-0225f8d20fbe.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['dilated vascular channels', 'papillary projections', 'enlarged endothelial cells', 'compressed vascular channels', 'extravasated erythrocytes']",
"noisy_text": " which will slowly risk halt. These lesions will stain, frequently with CD34, but also are strongly positive for D240. So they probably are of lymphatic origin rather than vascular origin. What one looks for is a biphasic vascular tumor with this central area characterized by these dilated vascular channels. Let's look at the bottom piece, which frequently do contain these papillary projections, which protrude into the lumina, these plump endothelial cells, and then at the periphery, more compressed vascular channels, which dissect between collagen bundles. And it's at the periphery one frequently sees extravasated erythrocytes, siderophages, and",
"corrected_text": " which will slowly risk halt. These lesions will stain, frequently with CD34, but also are strongly positive for D240. So they probably are of lymphatic origin rather than vascular origin. What one looks for is a biphasic vascular tumor with this central area characterized by these dilated vascular channels. Let's look at the bottom piece, which frequently do contain these papillary projections, which protrude into the lumina, these plump endothelial cells, and then at the periphery, more compressed vascular channels, which dissect between collagen bundles. And it's at the periphery one frequently sees extravasated erythrocytes, siderophages, and",
"med_umls_ids": "[[{'entity': 'Lesions', 'concept_id': 'C0221198', 'confidence': 1.0}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'CD34', 'concept_id': 'C0054953', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'D240', 'concept_id': 'C3766973', 'confidence': 0.5323090553283691}, {'entity': 'lymphatic origin', 'concept_id': 'C0229889', 'confidence': 0.7706887125968933}, {'entity': 'vascular origin', 'concept_id': 'C0395959', 'confidence': 0.7819716334342957}], [{'entity': 'biphasic', 'concept_id': 'C0205184', 'confidence': 1.0}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'dilated', 'concept_id': 'C0700124', 'confidence': 0.9999999403953552}, {'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}, {'entity': 'central area', 'concept_id': 'C0929543', 'confidence': 0.8492603302001953}], [{'entity': 'Papillary projections', 'concept_id': 'C0016538', 'confidence': 0.7451471090316772}, {'entity': 'bottom piece', 'concept_id': 'C1511276', 'confidence': 0.722324788570404}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}], [{'entity': 'Enlarged endothelial cells', 'concept_id': 'C0423263', 'confidence': 0.7785332202911377}, {'entity': 'papillary projections', 'concept_id': 'C0016538', 'confidence': 0.7451471090316772}], [{'entity': 'Compressed vascular channels', 'concept_id': 'C1336948', 'confidence': 0.5993747711181641}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}], [{'entity': 'Extravasated', 'concept_id': 'C0015376', 'confidence': 0.868863582611084}, {'entity': 'erythrocytes', 'concept_id': 'C0014772', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_704",
"caption_rating": "8"
},
{
"": "1006818",
"caption": "Loss of cellular polarity is seen in the sample.",
"image_path": "r7OA0Trj5hQ_image_7ac36f8d-6446-4fe7-9374-4deb58943b6d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['nuclei touching the top of the apical membrane', 'prominent nuclei', 'loss of cellular polarity', 'cribriform', 'micropapillary process']",
"noisy_text": " Can you all see the nuclei touching the top of the apical membrane? And see the prominent nuclei. And see the nuclei are running in different directions. This nuclei is running in this direction, whereas this nuclei is running in this direction. This nuclei is running in this direction. So there is loss of polarity. Okay, so here also it is stratified, reaching up to the top, and it is showing loss of polarity. And see the cribriformic. And this is a micropapillary process. Since it's a high power, you are not able to appreciate it better. I will show it to you in the other pictures. But here",
"corrected_text": " Can you all see the nuclei touching the top of the apical membrane? And see the prominent nuclei. And see the nuclei are running in different directions. This nuclei is running in this direction, whereas this nuclei is running in this direction. This nuclei is running in this direction. So there is loss of cellular polarity. Okay, so here also it is stratified, reaching up to the top, and it is showing loss of cellular polarity. And see the cribriform. And this is a micropapillary process. Since it's a high power, you are not able to appreciate it better. I will show it to you in the other pictures. But here",
"med_umls_ids": "[[{'entity': 'Loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'cellular polarity', 'concept_id': 'C0085304', 'confidence': 1.0}, {'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}], [{'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'stratified', 'concept_id': 'C0205363', 'confidence': 1.0}, {'entity': 'cribriform', 'concept_id': 'C1621425', 'confidence': 0.9999999403953552}, {'entity': 'micropapillary process', 'concept_id': 'C1290608', 'confidence': 0.763504683971405}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_705",
"caption_rating": "8"
},
{
"": "1005342",
"caption": "Perforating GA is a type of granulomatous condition that gives palisade granulostermatitis.",
"image_path": "udoW6VSqsm4_image_24d23039-b3f2-46db-8ca2-24721d0b7540.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['small individual papules', 'central crust', 'perioral skin', 'granulomatous condition', 'palisade granulostermatitis', 'neutrophilic dermatosis', 'older individuals', 'perineoplastic process']",
"noisy_text": " Yeah, this would be more kind of the classic one, probably. What else? Here's the classic one clinically. What if there's small individual papules that have a central crust in them, often on apral skin? We have had several cases of the disseminated GA, but I'm not sure if they didn't have a crust. So, what's the type that had it? Perforating? Perforating GA. Perforating GA, good. So, this was granulomanuary. There's one other condition that gives you palisade granulostermatitis like this, but it also gives you some neutrophils infiltrate. That palisade and neutrophilic granulostermatitis, that's another thing that you at least have to think about when you see GA. If you see an older person that's got disseminated GA, think about it as a perineoplastic process. Sometimes you",
"corrected_text": " Yeah, this would be more kind of the classic one, probably. What else? Here's the classic one clinically. What if there's small individual papules that have a central crust in them, often on perioral skin? We have had several cases of the disseminated GA, but I'm not sure if they didn't have a crust. So, what's the type that had it? Perforating? Perforating GA. Perforating GA, good. So, this was granulomatous. There's one other condition that gives you palisade granulostermatitis like this, but it also gives you some neutrophils infiltrate. That palisade and neutrophilic dermatosis, that's another thing that you at least have to think about when you see GA. If you see an older person that's got disseminated GA, think about it as a perineoplastic process. Sometimes you",
"med_umls_ids": "[[{'entity': 'Clinical', 'concept_id': 'C0205210', 'confidence': 1.0}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'skin condition', 'concept_id': 'C1719933', 'confidence': 1.0}, {'entity': 'individual', 'concept_id': 'C0027361', 'confidence': 1.0}, {'entity': 'papules', 'concept_id': 'C0332563', 'confidence': 0.9999999403953552}, {'entity': 'central crust', 'concept_id': 'C0205204', 'confidence': 0.7633819580078125}, {'entity': 'perioral skin', 'concept_id': 'C0448802', 'confidence': 0.8075158596038818}], [{'entity': 'Perforating', 'concept_id': 'C0549099', 'confidence': 1.0}, {'entity': 'GA', 'concept_id': 'C0002915', 'confidence': 1.0}, {'entity': 'granulomatous condition', 'concept_id': 'C0439667', 'confidence': 0.8219265341758728}, {'entity': 'palisade', 'concept_id': 'C0331512', 'confidence': 0.8241410255432129}, {'entity': 'granulostermatitis', 'concept_id': 'C0743086', 'confidence': 0.7311265468597412}], [{'entity': 'Neutrophilic dermatosis', 'concept_id': 'C1142272', 'confidence': 1.0}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'GA', 'concept_id': 'C0002915', 'confidence': 1.0}], [{'entity': 'Disseminated', 'concept_id': 'C0205221', 'confidence': 1.0}, {'entity': 'GA', 'concept_id': 'C0002915', 'confidence': 1.0}, {'entity': 'older', 'concept_id': 'C0337524', 'confidence': 0.7771234512329102}, {'entity': 'individuals', 'concept_id': 'C0027361', 'confidence': 0.8766164779663086}, {'entity': 'perineoplastic process', 'concept_id': 'C0027671', 'confidence': 0.8771522045135498}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_706",
"caption_rating": "7"
},
{
"": "1007861",
"caption": "The lesion is a localized, circumscribed area without granulomatous abnormalities or dyskeratotic keratinocytes, ruling out porokeratosis.",
"image_path": "udoW6VSqsm4_image_d6b4ac1d-f599-4c3a-8e61-a2c9de93d69d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['loss of the cornified layer']",
"noisy_text": " And so, the other things we kind of talked about are a bit differential, but next slide. Nothing else really will give you this kind of localized circumscribed area like this, so it's not poro. That would have a coronal lamella with granulocidal abnormalities and dyskeratonic keratinocytes. We don't see that here, so this is just a loss of the coronified layer. And there's one other condition where you kind of get, where are some other little clonal, you know, somatic mutations that you can get abnormalities in the epithelium that occur just in localized areas. That's not like loss of the coronified layer. We'll put a couple of other diseases where you see just local areas that are abnormal, and you get normal skin to the side. So, poro is one. We'll put",
"corrected_text": " And so, the other things we kind of talked about are a bit differential, but next slide. Nothing else really will give you this kind of localized circumscribed area like this, so it's not poro. That would have a coronal lamella with granulomatous abnormalities and dyskeratotic keratinocytes. We don't see that here, so this is just a loss of the cornified layer. And there's one other condition where you kind of get, where are some other little clonal, you know, somatic mutations that you can get abnormalities in the epithelium that occur just in localized areas. That's not like loss of the cornified layer. We'll put a couple of other diseases where you see just local areas that are abnormal, and you get normal skin to the side. So, poro is one. We'll put",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'localized', 'concept_id': 'C0392752', 'confidence': 1.0}, {'entity': 'circumscribed area', 'concept_id': 'C1282914', 'confidence': 0.9260231852531433}, {'entity': 'granulomatous abnormalities', 'concept_id': 'C0439667', 'confidence': 0.7099277377128601}, {'entity': 'dyskeratotic keratinocytes', 'concept_id': 'C1512099', 'confidence': 0.9701507091522217}, {'entity': 'porokeratosis', 'concept_id': 'C0162839', 'confidence': 1.0}], [{'entity': 'loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'cornified layer', 'concept_id': 'C3554359', 'confidence': 0.8562335968017578}], [{'entity': 'conditions', 'concept_id': 'C0012634', 'confidence': 0.8556983470916748}, {'entity': 'localized', 'concept_id': 'C0392752', 'confidence': 1.0}, {'entity': 'abnormality', 'concept_id': 'C1704258', 'confidence': 1.0}, {'entity': 'somatic mutations', 'concept_id': 'C0544886', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_707",
"caption_rating": "9"
},
{
"": "1006049",
"caption": "Excessive bleeding within the tumor and brown pigment near the surface, likely hemocyanin rather than melanin.",
"image_path": "8S4LeiO6Bbk_image_02e79690-5b3a-4acd-b1f7-045efdd9787d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['infiltrate filling the dermis and extending into the subcutaneous tissue', 'brown pigment near the surface', 'hyperplastic epidermis', 'cellular infiltrate throughout the dermis', 'infiltrate filling the dermis and extending into the subcutaneous tissue', 'brown pigment near the surface', 'hyperplastic epidermis', 'cellular infiltrate throughout the dermis']",
"noisy_text": " a large punch biopsy. And I think this actually was two punch biopsies from one lesion, each one bisected. And we can see that we've got an infiltrate filling the dermis and extending into the subcutaneous tissue. The infiltrate appears to be compressing the fat rather than growing in between the adipocytes. And I think it's scanning magnification, you know, one of the things that you can really begin to appreciate, not only the fact that this lesion is partially sampled, that it extends to the base and edges of the specimen, but one can begin to appreciate abundant hemorrhage within this tumor. And in addition, we can see some brown pigment near the surface. And common sense will tell you where there's smoke, there's fire. Since we do have all this abundant hemorrhage, there's a high probability that the pigment, this brownish gold pigment that we're seeing up near the surface of the specimen is likely hemocentaurant rather than melanin. But we'll confirm that when we go down to a higher power. As we move in, we can see that the epidermis is slightly hyperplastic. We've got this cellular infiltrate throughout the dermis and we'll need to go down and take a look at this infiltrate. It appears a little less dense at the",
"corrected_text": " a large punch biopsy. And I think this actually was two punch biopsies from one lesion, each one bisected. And we can see that we've got an infiltrate filling the dermis and extending into the subcutaneous tissue. The infiltrate appears to be compressing the fat rather than growing in between the adipocytes. And I think it's scanning magnification, you know, one of the things that you can really begin to appreciate, not only the fact that this lesion is partially sampled, that it extends to the base and edges of the specimen, but one can begin to appreciate abundant hemorrhage within this tumor. And in addition, we can see some brown pigment near the surface. And common sense will tell you where there's smoke, there's fire. Since we do have all this abundant hemorrhage, there's a high probability that the pigment, this brownish gold pigment that we're seeing up near the surface of the specimen is likely hemocentaurant rather than melanin. But we'confirm that when we go down to a higher power. As we move in, we can see that the epidermis is slightly hyperplastic. We've got this cellular infiltrate throughout the dermis and we'll need to go down and take a look at this infiltrate. It appears a little less dense at the",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'punch biopsy', 'concept_id': 'C0182557', 'confidence': 1.0}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'filling', 'concept_id': 'C0178866', 'confidence': 0.7777882218360901}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'subcutaneous tissue', 'concept_id': 'C0222331', 'confidence': 1.0}], [{'entity': 'Excessive', 'concept_id': 'C0442802', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'brown pigment near', 'concept_id': 'C4555503', 'confidence': 0.865685760974884}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}], [{'entity': 'hyperplastic epidermis', 'concept_id': 'C4748317', 'confidence': 0.7633129358291626}, {'entity': 'cellular infiltrate', 'concept_id': 'C1692321', 'confidence': 1.0}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_708",
"caption_rating": "8"
},
{
"": "1007295",
"caption": "Localized abnormalities in the epithelium can occur due to somatic mutations, such as in poro and clear cell acanthoma.",
"image_path": "udoW6VSqsm4_image_2245d98c-287f-45ab-b770-2cef8c919522.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['abnormalities in localized areas of the epithelium', 'clear staining glycogenated keratinocytes', 'basal cell-like appearance of clear cell acanthoma.', 'abnormalities in localized areas of the epithelium', 'clear staining glycogenated keratinocytes', 'basal cell-like appearance of clear cell acanthoma.']",
"noisy_text": " And there's one other condition where you kind of get, where are some other little clonal, you know, somatic mutations that you can get abnormalities in the epithelium that occur just in localized areas. That's not like loss of the coronified layer. We'll put a couple of other diseases where you see just local areas that are abnormal, and you get normal skin to the side. So, poro is one. We'll put a couple of others. So, it looked like psoriasis, and it had a lot of clear staining glycogenated keratinocytes. It was just one little localized packet. It looked like a basal cell. Yeah, clear cellular acanthoma. What if",
"corrected_text": " And there's one other condition where you kind of get, where are some other little clonal, you know, somatic mutations that you can get abnormalities in the epithelium that occur just in localized areas. That's not like loss of the cornified layer. We'll put a couple of other diseases where you see just local areas that are abnormal, and you get normal skin to the side. So, poro is one. We'll put a couple of others. So, it looked like psoriasis, and it had a lot of clear staining glycogenated keratinocytes. It was just one little localized packet. It looked like a basal cell. Yeah, clear cellular acanthoma. What if",
"med_umls_ids": "[[{'entity': 'Localized abnormalities', 'concept_id': 'C1844614', 'confidence': 0.7790723443031311}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'somatic mutations', 'concept_id': 'C0544886', 'confidence': 1.0}, {'entity': 'poro', 'concept_id': 'C1012232', 'confidence': 0.8632686734199524}, {'entity': 'cell acanthoma', 'concept_id': 'C0333992', 'confidence': 0.841953456401825}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_709",
"caption_rating": "8"
},
{
"": "1006649",
"caption": "The internal control glands are staining for both nuclear and membranous cytoplasmic stains.",
"image_path": "iklRyY1nBIE_image_fbc5b269-fc07-4337-8b78-bc8312f6d9b0.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['nuclear stain', 'membranous cytoplasmic stain', 'prostate cancer', 'P63', 'nuclear stain', 'membranous cytoplasmic stain', 'prostate cancer', 'P63']",
"noisy_text": " if you look carefully, is actually negative. The only thing that is positive is a nuclear stain, which is the P63. Again, you want to look at your internal control. These are the glands that were comfortable or benign. You can see they're staining for both nuclear stain and membranous wispy cytoplasmic stain, which is the hemoglobin cytokeratin. In this baccalaureate case, the racemase was predominantly negative. There's a hint of staining in areas, but it's predominantly negative. What is striking, what is very striking, is the fact that the P63 is diffusely positive, which they found very odd. And so this",
"corrected_text": " if you look carefully, is actually negative. The only thing that is positive is a nuclear stain, which is the P63. Again, you want to look at your internal control. These are the glands that were comfortable or benign. You can see they're staining for both nuclear stain and membranous wispy cytoplasmic stain, which is the hemoglobin cytokeratin. In this baccalaureate case, the racemase was predominantly negative. There's a hint of staining in areas, but it's predominantly negative. What is striking, what is very striking, is the fact that the P63 is diffusely positive, which they found very odd. And so this",
"med_umls_ids": "[[{'entity': 'positive stain', 'concept_id': 'C1446409', 'confidence': 0.8016907572746277}, {'entity': 'nuclear stain', 'concept_id': 'C0521447', 'confidence': 0.8163275122642517}, {'entity': 'P63', 'concept_id': 'C1422009', 'confidence': 1.0}], [{'entity': 'internal control glands', 'concept_id': 'C0597937', 'confidence': 0.7678565979003906}, {'entity': 'staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'nuclear', 'concept_id': 'C0521447', 'confidence': 1.0}, {'entity': 'membranous', 'concept_id': 'C0025255', 'confidence': 1.0}], [{'entity': 'Racemase', 'concept_id': 'C0034503', 'confidence': 1.0}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'prostate cancer', 'concept_id': 'C0376358', 'confidence': 1.0}], [{'entity': 'P63', 'concept_id': 'C1422009', 'confidence': 1.0}, {'entity': 'diffusely', 'concept_id': 'C0205219', 'confidence': 0.8011853098869324}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_710",
"caption_rating": "8"
},
{
"": "1009100",
"caption": "Presence of lymphocytes and hints of duct formation within the tumor.",
"image_path": "8S4LeiO6Bbk_image_8b0e842c-7338-491f-9fb9-2928932f01f6.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['epithelial tumor', 'cytoplasm', 'vesicular chromatin pattern', 'lymphocytes', 'duct formation', 'lymphocytes']",
"noisy_text": " If we move to higher power, we can see that we're dealing with an epithelial rather than a mosaicable tumor. We've got interconnected cords and strands. We have somewhat of a ribiform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of the cells are round to oval. They're fairly large. These cells have some faint eosinophilic to pale gray cytoplasm, although this cytoplasm is kind of difficult to see. Some of these cells have an evenly dispersed or vesicular chromatin pattern, and other nuclei are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and",
"corrected_text": " If we move to higher power, we can see that we're dealing with an epithelial rather than a mesenchymal tumor. We've got interconnected cords and strands. We have somewhat of a cribriform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of the cells are round to oval. They're fairly large. These cells have some faint eosinophilic to pale gray cytoplasm, although this cytoplasm is kind of difficult to see. Some of these cells have an evenly dispersed or vesicular chromatin pattern, and other nuclei are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'epithelial tumor', 'concept_id': 'C1368683', 'confidence': 0.9999999403953552}, {'entity': 'cords', 'concept_id': 'C0034869', 'confidence': 0.801885187625885}, {'entity': 'strands', 'concept_id': 'C0600383', 'confidence': 0.800572395324707}], [{'entity': 'Cribriform pattern', 'concept_id': 'C1333163', 'confidence': 1.0}, {'entity': 'loose', 'concept_id': 'C0205407', 'confidence': 1.0}, {'entity': 'edematous', 'concept_id': 'C0013604', 'confidence': 1.0}, {'entity': 'vascular stroma', 'concept_id': 'C0005847', 'confidence': 0.8046398758888245}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'cell types', 'concept_id': 'C0007634', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'eosinophilic', 'concept_id': 'C0333930', 'confidence': 1.0}, {'entity': 'pale', 'concept_id': 'C0030232', 'confidence': 1.0}, {'entity': 'gray cytoplasm', 'concept_id': 'C0010834', 'confidence': 0.8177905678749084}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'duct', 'concept_id': 'C0687028', 'confidence': 1.0}, {'entity': 'formation', 'concept_id': 'C0220781', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_711",
"caption_rating": "8"
},
{
"": "1007246",
"caption": "EMA, Clodin-1, and Glut-1 are immunohistochemical stains that can help diagnose perineuriomas, but low-grade fibrosarcomas can also express EMA and Clodin-1.",
"image_path": "QDb68_G1HR4_image_7807ddd7-4e7e-4a1d-aeba-2e2b021c55bc.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Deep soft tissue', 'Perineurioma', 'Low-grade fibromyxoid sarcoma', 'Immunohistochemistry', 'Swirling growth']",
"noisy_text": " involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is more of a difficult problem because perineurioma has a lot of overlap histologically with low-grade fibromyxoid sarcoma and also immunohistochemically. On immunostains, EMA, Clodin-1 and Glut-1 are three immunostains that will usually stain perineuriomas. The problem is that low-grade fibromyxoid sarcomas often express at least focal EMA, so that's a problem and additionally, the examples of low-grade fibromyxoid sarcoma that have dramatic swirling and whirling growth, those are the ones that have a perineurioma like pattern, the ones that mimic perineurioma. They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The",
"corrected_text": " involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is more of a difficult problem because perineurioma has a lot of overlap histologically with low-grade fibromyxoid sarcoma and also immunohistochemically. On immunostains, EMA, Clodin-1 and Glut-1 are three immunostains that will usually stain perineuriomas. The problem is that low-grade fibromyxoid sarcomas often express at least focal EMA, so that's a problem and additionally, the examples of low-grade fibromyxoid sarcoma that have dramatic swirling and whirling growth, those are the ones that have a perineurioma like pattern, the ones that mimic perineurioma. They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The",
"med_umls_ids": "[[{'entity': 'CD34', 'concept_id': 'C0054953', 'confidence': 1.0}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'deep soft tissue tumors', 'concept_id': 'C0037579', 'confidence': 0.8622524738311768}], [{'entity': 'Perineurioma', 'concept_id': 'C0751691', 'confidence': 0.9999999403953552}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'histologically', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'immunohistochemistry', 'concept_id': 'C0021044', 'confidence': 0.9999998807907104}], [{'entity': 'EMA', 'concept_id': 'C0268596', 'confidence': 0.9999999403953552}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}, {'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'immunohistochemical stains', 'concept_id': 'C4317108', 'confidence': 0.9999999403953552}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibrosarcomas', 'concept_id': 'C0016057', 'confidence': 1.0}, {'entity': 'EMA', 'concept_id': 'C0268596', 'confidence': 0.9999999403953552}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}], [{'entity': 'Low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'swirling', 'concept_id': 'C0233591', 'confidence': 0.7064549922943115}, {'entity': 'growth', 'concept_id': 'C0018270', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'express', 'concept_id': 'C0017262', 'confidence': 0.8176293969154358}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}], [{'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'reports', 'concept_id': 'C0684224', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcomas', 'concept_id': 'C1275282', 'confidence': 0.8123146891593933}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_712",
"caption_rating": "8"
},
{
"": "1007294",
"caption": "Mitosis and apoptosis are also present in the dysplastic epithelium.",
"image_path": "r7OA0Trj5hQ_image_32417ed6-24b1-40eb-80cd-0e707d494e66.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Loss of cellular polarity and nuclear stratification reaching the top of the epithelium', 'Mitosis', 'Apoptosis', 'Dysplasia', 'Loss of cellular polarity and nuclear stratification reaching the top of the epithelium', 'Mitosis', 'Apoptosis', 'Dysplasia']",
"noisy_text": " Look at this nuclei running like in this direction. Look at this nuclei running in this direction. So clearly, loss of polarity. And the nuclear stratification is reaching the top of the epithelium, marked apoptosis. It's too thick to see the mitosis, but here you can see the mitosis. So this is stratification, loss of mucin, mitosis, apoptosis. So this is dysplasia. But this dysplasia is the epithelium is reaching the top. And there is loss of polarity. And I don't see probably crib reforming maybe coming here. I don't see in the center of the picture. So I will think",
"corrected_text": " Look at this nuclei running like in this direction. Look at this nuclei running in this direction. So clearly, loss of polarity. And the nuclear stratification is reaching the top of the epithelium, marked apoptosis. It's too thick to see the mitosis, but here you can see the mitosis. So this is stratification, loss of mucin, mitosis, apoptosis. So this is dysplasia. But this dysplasia is the epithelium is reaching the top. And there is loss of polarity. And I don't see probably cribriform maybe coming here. I don't see in the center of the picture. So I will think",
"med_umls_ids": "[[{'entity': 'Loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'cellular polarity', 'concept_id': 'C0085304', 'confidence': 1.0}, {'entity': 'nuclear', 'concept_id': 'C0521447', 'confidence': 1.0}, {'entity': 'stratification', 'concept_id': 'C1514983', 'confidence': 1.0}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'dysplasia', 'concept_id': 'C0334044', 'confidence': 1.0}], [{'entity': 'Mitosis', 'concept_id': 'C0026255', 'confidence': 0.9999998807907104}, {'entity': 'apoptosis', 'concept_id': 'C0162638', 'confidence': 1.0}, {'entity': 'dysplastic epithelium', 'concept_id': 'C1512100', 'confidence': 0.8234760165214539}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_713",
"caption_rating": "9"
},
{
"": "1008806",
"caption": "Several lymphocytes are present throughout the tumor.",
"image_path": "8S4LeiO6Bbk_image_ae5a7f91-b793-4d68-aae8-d47495618c20.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Two cell types, light and dark staining', 'Sprinkling of lymphocytes', 'Duct formation within the tumor', 'Edematous stroma', 'Spear adenoma']",
"noisy_text": " are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and a sprinkling of lymphocytes in concert with ducts in the tumor, and an edematous stroma are diagnostic of spear adenoma. And of course, this is one of the glandular neoplasm that shows differentiation towards the secretory component of this white gland. So very nice example here of",
"corrected_text": " are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and a sprinkling of lymphocytes in concert with ducts in the tumor, and an edematous stroma are diagnostic of spear adenoma. And of course, this is one of the glandular neoplasm that shows differentiation towards the secretory component of this white gland. So very nice example here of",
"med_umls_ids": "[[{'entity': 'Tumor cells', 'concept_id': 'C0431085', 'confidence': 1.0}, {'entity': 'dark', 'concept_id': 'C0332582', 'confidence': 0.9999999403953552}, {'entity': 'light staining', 'concept_id': 'C0487602', 'confidence': 0.7634408473968506}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}], [{'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}], [{'entity': 'Hints', 'concept_id': 'C1512348', 'confidence': 1.0}, {'entity': 'duct', 'concept_id': 'C0687028', 'confidence': 1.0}, {'entity': 'formation', 'concept_id': 'C0220781', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}], [{'entity': 'configuration', 'concept_id': 'C0449830', 'confidence': 1.0}, {'entity': 'cell types', 'concept_id': 'C0007634', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'ducts', 'concept_id': 'C0687028', 'confidence': 1.0}, {'entity': 'edematous stroma', 'concept_id': 'C1333376', 'confidence': 0.8675230145454407}, {'entity': 'diagnostic', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'spear adenoma', 'concept_id': 'C0001430', 'confidence': 0.7512055039405823}], [{'entity': 'Spear adenoma', 'concept_id': 'C0001430', 'confidence': 0.7512055039405823}, {'entity': 'glandular neoplasm', 'concept_id': 'C0205854', 'confidence': 1.0}, {'entity': 'differentiation', 'concept_id': 'C0007589', 'confidence': 1.0}, {'entity': 'secretory', 'concept_id': 'C1327616', 'confidence': 1.0}, {'entity': 'gland', 'concept_id': 'C1285092', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_714",
"caption_rating": "8"
},
{
"": "1009398",
"caption": "Different tumors with FUS gene rearrangements have a different histologic appearance.",
"image_path": "QDb68_G1HR4_image_d8885f68-50d4-4206-9c20-cccbea5b6876.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " But do be aware that there are many other tumors in soft tissue pathology that have FUS rearrangements, myxoid liposarcoma and others. They usually have a different histologic appearance. So that's why you can never use, at least in my opinion, you shouldn't use molecular pathology by itself. You have to couple it with the clinical scenario and the histologic features and the immunostain findings. Put all of the picture together and make sure that the diagnosis makes sense. If it doesn't make sense, I always try to stop and think what's wrong here? Is something not working? Is the test false positive? What's the problem? Why doesn't this all add up? Of course",
"corrected_text": " But do be aware that there are many other tumors in soft tissue pathology that have FUS gene rearrangements, myxoid liposarcoma and others. They usually have a different histologic appearance. So that's why you can never use, at least in my opinion, you shouldn't use molecular pathology by itself. You have to couple it with the clinical scenario and the histologic features and the immunostain findings. Put all of the picture together and make sure that the diagnosis makes sense. If it doesn't make sense, I always try to stop and think what's wrong here? Is something not working? Is the test false positive? What's the problem? Why doesn't this all add up? Of course",
"med_umls_ids": "[[{'entity': 'FUS', 'concept_id': 'C0268696', 'confidence': 1.0}, {'entity': 'gene rearrangements', 'concept_id': 'C0017287', 'confidence': 0.9999998807907104}, {'entity': 'soft tissue tumors', 'concept_id': 'C0037579', 'confidence': 1.0}, {'entity': 'myxoid liposarcoma', 'concept_id': 'C0206634', 'confidence': 1.0}], [{'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'FUS', 'concept_id': 'C0268696', 'confidence': 1.0}, {'entity': 'gene rearrangements', 'concept_id': 'C0017287', 'confidence': 0.9999998807907104}, {'entity': 'histologic', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}], [{'entity': 'Molecular pathology', 'concept_id': 'C0596962', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'coupled', 'concept_id': 'C1948027', 'confidence': 1.0}, {'entity': 'clinical scenario', 'concept_id': 'C0205210', 'confidence': 0.6381967067718506}, {'entity': 'histologic features', 'concept_id': 'C1301121', 'confidence': 0.816085159778595}, {'entity': 'immunohistochemistry', 'concept_id': 'C0021044', 'confidence': 0.9999998807907104}, {'entity': 'findings', 'concept_id': 'C2607943', 'confidence': 1.0}], [{'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_715",
"caption_rating": "8"
},
{
"": "1008521",
"caption": "There is loss of the cornified layer.",
"image_path": "udoW6VSqsm4_image_e9958770-87f7-412e-ace5-f8aafa60a9e6.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['loss of the cornified layer']",
"noisy_text": " And so, the other things we kind of talked about are a bit differential, but next slide. Nothing else really will give you this kind of localized circumscribed area like this, so it's not poro. That would have a coronal lamella with granulocidal abnormalities and dyskeratonic keratinocytes. We don't see that here, so this is just a loss of the coronified layer. And there's one other condition where you kind of get, where are some other little clonal, you know, somatic mutations that you can get abnormalities in the epithelium that occur just in localized areas. That's not like loss of the coronified layer. We'll put a couple of other diseases where you see just local areas that are abnormal, and you get normal skin to the side. So, poro is one. We'll put",
"corrected_text": " And so, the other things we kind of talked about are a bit differential, but next slide. Nothing else really will give you this kind of localized circumscribed area like this, so it's not poro. That would have a coronal lamella with granulomatous abnormalities and dyskeratotic keratinocytes. We don't see that here, so this is just a loss of the cornified layer. And there's one other condition where you kind of get, where are some other little clonal, you know, somatic mutations that you can get abnormalities in the epithelium that occur just in localized areas. That's not like loss of the cornified layer. We'll put a couple of other diseases where you see just local areas that are abnormal, and you get normal skin to the side. So, poro is one. We'll put",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'localized', 'concept_id': 'C0392752', 'confidence': 1.0}, {'entity': 'circumscribed area', 'concept_id': 'C1282914', 'confidence': 0.9260231852531433}, {'entity': 'granulomatous abnormalities', 'concept_id': 'C0439667', 'confidence': 0.7099277377128601}, {'entity': 'dyskeratotic keratinocytes', 'concept_id': 'C1512099', 'confidence': 0.9701507091522217}, {'entity': 'porokeratosis', 'concept_id': 'C0162839', 'confidence': 1.0}], [{'entity': 'loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'cornified layer', 'concept_id': 'C3554359', 'confidence': 0.8562335968017578}], [{'entity': 'conditions', 'concept_id': 'C0012634', 'confidence': 0.8556983470916748}, {'entity': 'localized', 'concept_id': 'C0392752', 'confidence': 1.0}, {'entity': 'abnormality', 'concept_id': 'C1704258', 'confidence': 1.0}, {'entity': 'somatic mutations', 'concept_id': 'C0544886', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_716",
"caption_rating": "7"
},
{
"": "1008221",
"caption": "The presence of pepper-like copper chromatin suggests a neuroendocrine carcinoma.",
"image_path": "Wiyo6taYRF4_image_f2fd3cc2-b10f-44d2-aa3a-167b1cde6571.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Hematopathology', 'Neuropathology', 'Cytopathology']",
"roi_text": "['neuroendocrine carcinoma', 'hyperchromatic nuclei', 'vesicular nuclei', 'nucleoli', 'salt and pepper chromatin', 'nucleoli', 'salt and pepper chromatin']",
"noisy_text": " and pepper like copper chromatin, that means you're telling that this is most likely a neuroendocrine kind of a carcinoma. So those are the different types of nuclei that we have seen. Again, to go back at the reference, we are going to look at the plasma cell. In the plasma cell, we can easily identify the hetero and the vesicular areas, that is heterochromatin and nucleomatin. If the cell is entirely composed of heterochromatin, it will be very dark-staining. And this is called as hyperchromatic nuclei. If it is composed of lightly-stained nuclei, lightly-stained areas, then it is called vesicular nuclei. A vesicular nuclei is usually accompanied by a nucleoli. And if you have very finely granular dark and light areas, then it is called as salt and pepper chromatin. And these are the defining features for a neuroendocrine tumor. Now, once we have understood the staining pattern of the",
"corrected_text": " and pepper like copper chromatin, that means you're telling that this is most likely a neuroendocrine kind of a carcinoma. So those are the different types of nuclei that we have seen. Again, to go back at the reference, we are going to look at the plasma cell. In the plasma cell, we can easily identify the hetero and the vesicular areas, that is heterochromatin and nucleoplasm. If the cell is entirely composed of heterochromatin, it will be very hyperchromatic. And this is called as hyperchromatic nuclei. If it is composed of lightly-stained areas, lightly-stained areas, then it is called vesicular nuclei. A vesicular nuclei is usually accompanied by a nucleoli. And if you have very finely granular dark and light areas, then it is called as salt and pepper chromatin. And these are the defining features for a neuroendocrine tumor. Now, once we have understood the staining pattern of the",
"med_umls_ids": "[[{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'pepper-like copper chromatin', 'concept_id': 'C0453397', 'confidence': 0.5605897903442383}, {'entity': 'neuroendocrine carcinoma', 'concept_id': 'C0206695', 'confidence': 1.0}], [{'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'observed', 'concept_id': 'C1441672', 'confidence': 1.0}, {'entity': 'hyperchromatic', 'concept_id': 'C0333911', 'confidence': 1.0}, {'entity': 'vesicular nuclei', 'concept_id': 'C2325471', 'confidence': 0.7651268839836121}], [{'entity': 'Heterochromatin', 'concept_id': 'C0019397', 'confidence': 1.0}, {'entity': 'nucleoplasm', 'concept_id': 'C0682537', 'confidence': 1.0}, {'entity': 'identified', 'concept_id': 'C0205396', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}], [{'entity': 'Vesicular nuclei', 'concept_id': 'C2325471', 'confidence': 0.7651268839836121}, {'entity': 'nucleoli', 'concept_id': 'C0007609', 'confidence': 0.8710004091262817}], [{'entity': 'Salt', 'concept_id': 'C0036140', 'confidence': 1.0}, {'entity': 'pepper chromatin', 'concept_id': 'C0008546', 'confidence': 0.7025638818740845}, {'entity': 'neuroendocrine tumor', 'concept_id': 'C0206754', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1152.0",
"id": "test_717",
"caption_rating": "9"
},
{
"": "1005320",
"caption": "The neoplasm has a relatively dense fibrous stroma, unlike the loose and mixoid stroma seen around basal cell carcinoma.",
"image_path": "LlPaENuqzVQ_image_e41eadb4-ec94-4b64-af23-4f0f02dfac1a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['nevus sebaceus hamartoma', 'epithelial and follicular elements', 'perifollicular connective tissue', 'dense fibrous stroma', 'basal cell carcinoma', 'clefting', 'nevus sebaceus hamartoma', 'epithelial and follicular elements', 'perifollicular connective tissue', 'dense fibrous stroma', 'basal cell carcinoma', 'clefting']",
"noisy_text": " because it grows back, because there's also a soil component in addition to the growth on top of the soil. You've got to have the background stroma, which is part of the nevus sebaceus hammertoma as well. So this is a similar kind of deal. It's a neoplasm involving both the epithelial and the follicular elements, as well as the perifollicular connective tissue. And it's kind of got this pretty characteristic, it's kind of a relatively dense fibrous stroma. It's not loose and mixoid like the stroma you see around the basal cell carcinoma. Notice that there's no clefting between this, like we see with the basal cell carcinoma. So this",
"corrected_text": " because it grows back, because there's also a soil component in addition to the growth on top of the soil. You've got to have the background stroma, which is part of the nevus sebaceus hammertoma as well. So this is a similar kind of deal. It's a neoplasm involving both the epithelial and the follicular elements, as well as the perifollicular connective tissue. And it's kind of got this pretty characteristic, it's kind of a relatively dense fibrous stroma. It's not loose and mixoid like the stroma you see around the basal cell carcinoma. Notice that there's no clefting between this, like we see with the basal cell carcinoma. So this",
"med_umls_ids": "[[{'entity': 'Nevus sebaceus hamartoma', 'concept_id': 'C4476818', 'confidence': 0.8189855217933655}, {'entity': 'epithelial', 'concept_id': 'C0221908', 'confidence': 1.0}, {'entity': 'follicular', 'concept_id': 'C0439682', 'confidence': 1.0}, {'entity': 'elements', 'concept_id': 'C0013879', 'confidence': 1.0}, {'entity': 'perifollicular', 'concept_id': 'C1704236', 'confidence': 0.805053174495697}, {'entity': 'connective tissue', 'concept_id': 'C0009780', 'confidence': 1.0}], [{'entity': 'neoplasm', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}, {'entity': 'loose', 'concept_id': 'C0205407', 'confidence': 1.0}, {'entity': 'mixoid', 'concept_id': 'C3850557', 'confidence': 0.7173998355865479}, {'entity': 'stroma', 'concept_id': 'C0927195', 'confidence': 1.0}, {'entity': 'basal cell carcinoma', 'concept_id': 'C0007117', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_718",
"caption_rating": "9"
},
{
"": "1005665",
"caption": "The patient is a solid organ transplant recipient with mycophenol-associated injury.",
"image_path": "sDFjOtMAYrk_image_214d2a70-69d1-4660-9b43-434241da4ecc.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['Pyloric gland metaplasia']",
"noisy_text": " It's really dramatic, right? And not only that, what else do we have? Yeah, these cells, these glands right here. What is it? Yeah, exactly. It's a pyloric glomeruloplasia. So pyloric glomeruloplasia should be Crohn's. No, you can see pyloric glomeruloplasia in your sort of a colitis and end-associated injury and also in microphenol-associated injury, as this case is. And the tip of the patient is a solid organ transplant recipient. with microphenol-associated injury have many more in the way of eosinophils, a lot more in the way of eosinophils than GVHD patients do. So that's really, really helpful. Is there",
"corrected_text": " It's really dramatic, right? And not only that, what else do we have? Yeah, these cells, these glands right here. What is it? Yeah, exactly. It's a pyloric gland metaplasia. So pyloric gland metaplasia should be Crohn's. No, you can see pyloric gland metaplasia in your sort of a colitis and end-associated injury and also in mycophenol-associated injury, as this case is. And the tip of the patient is a solid organ transplant recipient. with mycophenol-associated injury have many more in the way of eosinophils, a lot more in the way of eosinophils than GVHD patients do. So that's really, really helpful. Is there",
"med_umls_ids": "[[{'entity': 'Pyloric gland', 'concept_id': 'C0227239', 'confidence': 1.0}, {'entity': 'metaplasia', 'concept_id': 'C0025568', 'confidence': 1.0}, {'entity': 'colitis', 'concept_id': 'C0009319', 'confidence': 1.0}, {'entity': 'end-associated injury', 'concept_id': 'C0552509', 'confidence': 0.6716579794883728}, {'entity': 'mycophenol-associated injury', 'concept_id': 'C0552509', 'confidence': 0.6023857593536377}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'solid organ transplant', 'concept_id': 'C0730400', 'confidence': 1.0}, {'entity': 'recipient', 'concept_id': 'C1709854', 'confidence': 1.0}, {'entity': 'mycophenol-associated injury', 'concept_id': 'C0552509', 'confidence': 0.6023857593536377}], [{'entity': 'Mycophenol-associated injury', 'concept_id': 'C0552509', 'confidence': 0.6023857593536377}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'GVHD', 'concept_id': 'C0018133', 'confidence': 1.0}, {'entity': 'patients', 'concept_id': 'C0030705', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_719",
"caption_rating": "8"
},
{
"": "1004246",
"caption": "Muscle bundles are seen in the lamina propria due to hyperplasia of the muscularis mucosa.",
"image_path": "r7OA0Trj5hQ_image_e281e036-beef-4673-b94e-a2e73f4043c9.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['muscle', 'lamina propria', 'muscularis mucosa', 'chemical gastritis', 'mucosal prolapse', 'solitary rectal ulcer syndrome', 'muscle', 'lamina propria', 'muscularis mucosa', 'chemical gastritis', 'mucosal prolapse', 'solitary rectal ulcer syndrome']",
"noisy_text": " You see in the hyperwire, muscle coming in the lamina propria. Lamina propria should be free of musculature. The muscle should be there only in the muscularis mucosa. Here in this low power, you can see the muscularis mucosa is hyperplastic. And it is sending the muscle bundle into the lamina propria. This happens in chemical gastritis in case of stomach and in cases of mucosal prolapse in colon. Remember that solitary rectal ulcer syndrome, which is totally misnomer. It is neither solitary, can be seen in other parts other than rectum. There may not be any ulcer, there is no syndrome. So the whole solitary rectal ulcer syndrome is a misnomer. But muscularization of the lamina propria is one of the criteria for mucosal prolapse that is happening in",
"corrected_text": " You see in the hyperplasia, muscle coming in the lamina propria. Lamina propria should be free of musculature. The muscle should be there only in the muscularis mucosa. Here in this low power, you can see the muscularis mucosa is hyperplastic. And it is sending the muscle bundle into the lamina propria. This happens in chemical gastritis in case of stomach and in cases of mucosal prolapse in colon. Remember that solitary rectal ulcer syndrome, which is totally misnomer. It is neither solitary, can be seen in other parts other than rectum. There may not be any ulcer, there is no syndrome. So the whole solitary rectal ulcer syndrome is a misnomer. But muscularization of the lamina propria is one of the criteria for mucosal prolapse that is happening in",
"med_umls_ids": "[[{'entity': 'Muscle hyperplasia', 'concept_id': 'C2265913', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'abnormal', 'concept_id': 'C0205161', 'confidence': 1.0}, {'entity': 'muscularis mucosa', 'concept_id': 'C0225357', 'confidence': 0.9999998807907104}], [{'entity': 'Muscle bundles', 'concept_id': 'C0504095', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'hyperplasia', 'concept_id': 'C0020507', 'confidence': 1.0}, {'entity': 'muscularis mucosa', 'concept_id': 'C0225357', 'confidence': 0.9999998807907104}], [{'entity': 'Muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'criterion', 'concept_id': 'C0243161', 'confidence': 1.0}, {'entity': 'mucosal prolapse', 'concept_id': 'C0034888', 'confidence': 0.826268196105957}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_720",
"caption_rating": "8"
},
{
"": "1008914",
"caption": "The typical storiform pattern is also present in this case.",
"image_path": "LlPaENuqzVQ_image_8d7a5078-12be-49d3-8929-42114f40a33a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['honeycomb morphology', 'lipocytes', 'typical storiform pattern']",
"noisy_text": " this is a clue to this diagnosis. You can make this diagnosis at low power when you see this pattern. This is a honeycomb morphology. Rarely anything does this except dramatic fibrosarcoma tuberans. Okay, when you see this pattern, you can impress your friends and colleagues. You can say, this is DFSB. You don't need the storiform pattern. If you see this, you got the diagnosis. No other neoplasm really gets diffusely between and among lipocytes in a diffuse pattern like this, other than DFSB. Now you look up here and yeah, you do have the nice, beautiful storiform pattern here. And you don't really need a CD34 stain here. You can do it",
"corrected_text": " this is a clue to this diagnosis. You can make this diagnosis at low power when you see this pattern. This is a honeycomb morphology. Rarely anything does this except desmoplastic fibroblastoma. Okay, when you see this pattern, you can impress your friends and colleagues. You can say, this is DFSP. You don't need the typical storiform pattern. If you see this, you got the diagnosis. No other neoplasm really gets diffusely between and among lipocytes in a diffuse pattern like this, other than DFSP. Now you look up here and yeah, you do have the nice, typical typical storiform pattern here. And you don't really need a CD34 stain here. You can do it",
"med_umls_ids": "[[{'entity': 'Honeycomb', 'concept_id': 'C0332468', 'confidence': 1.0}, {'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'desmoplastic fibroblastoma', 'concept_id': 'C0206645', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}], [{'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}, {'entity': 'neoplasm', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'diffusely', 'concept_id': 'C0205219', 'confidence': 0.8011853098869324}, {'entity': 'lipocytes', 'concept_id': 'C0206131', 'confidence': 1.0}, {'entity': 'diffuse pattern', 'concept_id': 'C1333299', 'confidence': 0.9999998807907104}], [{'entity': 'storiform pattern', 'concept_id': 'C1336510', 'confidence': 0.8142904043197632}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_721",
"caption_rating": "8"
},
{
"": "1005616",
"caption": "Presence of melanophages with variable size and shape.",
"image_path": "8S4LeiO6Bbk_image_65852f62-96f7-41e4-9c32-dff32a7a7ef2.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Melanin granules within melanophages', 'Melanin granules within melanophages', 'Extravasated erythrocytes', 'Increased melanin in the basilar keratinocytes.']",
"noisy_text": " or the melanophages is variable in size and shape. Now look at the melanin granules within this melanophage, and you can see that they're much more uniform in size and shape. Now look at the melanin granules within this melanophage, and you can see that they're much more uniform in size than the hemocentauric pigment in the centaurifages. It also tends to be a little bit darker staining, but sometimes it can be very difficult, tinctorially, depending upon the staining quality, to use color to distinguish the two, better to use size and context clues. Also note here we don't have any extravasated erythrocytes here, so much more likely to be melanin, and there's an increased melanin in the basilar keratinocytes. Getting back to the case, thin epidermis, bacular",
"corrected_text": " or the melanophages is variable in size and shape. Now look at the melanin granules within this melanophage, and you can see that they're much more uniform in size and shape. Now look at the melanin granules within this melanophage, and you can see that they're much more uniform in size than the hemosiderin pigment in the centroblasts. It also tends to be a little bit darker staining, but sometimes it can be very difficult, tinctorially, depending upon the staining quality, to use color to distinguish the two, better to use size and context clues. Also note here we don't have any extravasated erythrocytes here, so much more likely to be melanin, and there's an increased melanin in the basilar keratinocytes. Getting back to the case, thin epidermis, bacular",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'melanophages', 'concept_id': 'C3280463', 'confidence': 0.9375340938568115}, {'entity': 'variable size', 'concept_id': 'C1866144', 'confidence': 0.8559831976890564}, {'entity': 'shape', 'concept_id': 'C0332479', 'confidence': 1.0}], [{'entity': 'Melanin granules', 'concept_id': 'C0230692', 'confidence': 0.9174172878265381}, {'entity': 'melanophages', 'concept_id': 'C3280463', 'confidence': 0.9375340938568115}, {'entity': 'uniform', 'concept_id': 'C0205375', 'confidence': 1.0}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'shape', 'concept_id': 'C0332479', 'confidence': 1.0}, {'entity': 'hemosiderin', 'concept_id': 'C0019113', 'confidence': 1.0}, {'entity': 'pigment', 'concept_id': 'C0031911', 'confidence': 1.0}, {'entity': 'centroblasts', 'concept_id': 'C1517735', 'confidence': 0.8281925320625305}], [{'entity': 'Increased', 'concept_id': 'C0205217', 'confidence': 1.0}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}, {'entity': 'basilar keratinocytes', 'concept_id': 'C0022567', 'confidence': 0.803361713886261}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_722",
"caption_rating": "8"
},
{
"": "1006922",
"caption": "Surgical resection of solitary metastases from the lung may prolong the disease course.",
"image_path": "QDb68_G1HR4_image_13a66807-055f-4986-8c22-f11dbff4f623.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Metastasis to the lung or pleura']",
"noisy_text": " diagnosis when a metastasis finally shows up. So unfortunately, that's a frustrating thing I think for both the treating physicians and the patients to know that basically you're never totally in the clear these things can recur or metastasize very, very long after diagnosis. When they metastasize, they often go to the lung or the pleura and there probably is some benefit at least in the opinion of some of the people that I know who treat these sarcomas in removing solitary metastases from the lung if they're surgically amenable to surgical resection that you can remove the metastasis and then the patient may go quite a few more years before having another metastasis. So you can really kind of prolong the disease course by removing metastasis. Obviously if you're a patient watching this that has this tumor, please make sure you see an expert",
"corrected_text": " diagnosis when a metastasis finally shows up. So unfortunately, that's a frustrating thing I think for both the treating physicians and the patients to know that basically you're never totally in the clear these things can recur or metastasize very, very long after diagnosis. When they metastasize, they often go to the lung or the pleura and there probably is some benefit at least in the opinion of some of the people that I know who treat these sarcomas in removing solitary metastases from the lung if they're surgically amenable to surgical resection that you can remove the metastasis and then the patient may go quite a few more years before having another metastasis. So you can really kind of prolong the disease course by removing metastasis. Obviously if you're a patient watching this that has this tumor, please make sure you see an expert",
"med_umls_ids": "[[{'entity': 'Metastasis', 'concept_id': 'C0027627', 'confidence': 1.0}, {'entity': 'metastasize', 'concept_id': 'C0027627', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'lung', 'concept_id': 'C0024109', 'confidence': 1.0}, {'entity': 'pleura', 'concept_id': 'C0032225', 'confidence': 1.0}], [{'entity': 'Surgical resection', 'concept_id': 'C0015252', 'confidence': 1.0}, {'entity': 'solitary metastases', 'concept_id': 'C0027627', 'confidence': 0.7712292075157166}, {'entity': 'lung', 'concept_id': 'C0024109', 'confidence': 1.0}, {'entity': 'disease course', 'concept_id': 'C0242656', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_723",
"caption_rating": "8"
},
{
"": "1008804",
"caption": "MUC4 stain is used to confirm the diagnosis of cellular intramuscular myxoma.",
"image_path": "QDb68_G1HR4_image_8184162a-6f50-40b1-bc14-9c1f1ddf7962.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['myxoid features', 'fine delicate collagen', 'cellular intramuscular myxoma', 'fibrous areas', 'cellular areas', 'MUC4 stain']",
"noisy_text": " Here's again the myxoid background I really think this is very helpful. The very very fine delicate collagen that you see. Now areas like this I think can kind of resemble what you see in a so-called cellular intramuscular myxoma. Intramuscular myxomas are usually very blue and myxoid very hypocellular but sometimes they get more fibrous and more cellular areas. And on a needle biopsy I think that can be challenging. So I think usually with some experience you can tell them apart on H and E most of the time but when I have any doubt I just do a MUC4 stain. The MUC4 is negative and on a needle it looks like a myxoma with some kind of fibrous or a little bit more cellular areas and then I just say that it's probably a cellular intramuscular myxoma. So I think MUC4",
"corrected_text": " Here's again the myxoid background I really think this is very helpful. The very very fine delicate collagen that you see. Now areas like this I think can kind of resemble what you see in a so-called cellular intramuscular myxoma. Intramuscular myxomas are usually very blue and myxoid very hypocellular but sometimes they get more fibrous and more cellular areas. And on a needle biopsy I think that can be challenging. So I think usually with some experience you can tell them apart on H and E most of the time but when I have any doubt I just do a MUC4 stain. The MUC4 is negative and on a needle it looks like a myxoma with some kind of fibrous or a little bit more cellular areas and then I just say that it's probably a cellular intramuscular myxoma. So I think MUC4",
"med_umls_ids": "[[{'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'myxoid', 'concept_id': 'C0205295', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}], [{'entity': 'narrator', 'concept_id': 'C1135957', 'confidence': 0.7711340188980103}, {'entity': 'cellular', 'concept_id': 'C0007634', 'confidence': 0.9999999403953552}, {'entity': 'intramuscular', 'concept_id': 'C0442117', 'confidence': 1.0}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}, {'entity': 'cellular areas', 'concept_id': 'C0007634', 'confidence': 0.7882957458496094}], [{'entity': 'MUC4', 'concept_id': 'C1417496', 'confidence': 0.9999999403953552}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'confirm', 'concept_id': 'C0521093', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'cellular intramuscular myxoma', 'concept_id': 'C1334260', 'confidence': 0.8910117149353027}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_724",
"caption_rating": "8"
},
{
"": "1007760",
"caption": "Slightly hyperplastic epidermis and a cellular infiltrate throughout the dermis.",
"image_path": "8S4LeiO6Bbk_image_feb3aa17-235d-4760-9899-94f3bc0c6832.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['brown pigment near the surface', 'infiltrate filling the dermis and extending into the subcutaneous tissue', 'brown pigment near the surface', 'hyperplastic epidermis', 'cellular infiltrate throughout the dermis']",
"noisy_text": " a large punch biopsy. And I think this actually was two punch biopsies from one lesion, each one bisected. And we can see that we've got an infiltrate filling the dermis and extending into the subcutaneous tissue. The infiltrate appears to be compressing the fat rather than growing in between the adipocytes. And I think it's scanning magnification, you know, one of the things that you can really begin to appreciate, not only the fact that this lesion is partially sampled, that it extends to the base and edges of the specimen, but one can begin to appreciate abundant hemorrhage within this tumor. And in addition, we can see some brown pigment near the surface. And common sense will tell you where there's smoke, there's fire. Since we do have all this abundant hemorrhage, there's a high probability that the pigment, this brownish gold pigment that we're seeing up near the surface of the specimen is likely hemocentaurant rather than melanin. But we'll confirm that when we go down to a higher power. As we move in, we can see that the epidermis is slightly hyperplastic. We've got this cellular infiltrate throughout the dermis and we'll need to go down and take a look at this infiltrate. It appears a little less dense at the",
"corrected_text": " a large punch biopsy. And I think this actually was two punch biopsies from one lesion, each one bisected. And we can see that we've got an infiltrate filling the dermis and extending into the subcutaneous tissue. The infiltrate appears to be compressing the fat rather than growing in between the adipocytes. And I think it's scanning magnification, you know, one of the things that you can really begin to appreciate, not only the fact that this lesion is partially sampled, that it extends to the base and edges of the specimen, but one can begin to appreciate abundant hemorrhage within this tumor. And in addition, we can see some brown pigment near the surface. And common sense will tell you where there's smoke, there's fire. Since we do have all this abundant hemorrhage, there's a high probability that the pigment, this brownish gold pigment that we're seeing up near the surface of the specimen is likely hemocentaurant rather than melanin. But we'confirm that when we go down to a higher power. As we move in, we can see that the epidermis is slightly hyperplastic. We've got this cellular infiltrate throughout the dermis and we'll need to go down and take a look at this infiltrate. It appears a little less dense at the",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'punch biopsy', 'concept_id': 'C0182557', 'confidence': 1.0}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'filling', 'concept_id': 'C0178866', 'confidence': 0.7777882218360901}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'subcutaneous tissue', 'concept_id': 'C0222331', 'confidence': 1.0}], [{'entity': 'Excessive', 'concept_id': 'C0442802', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'brown pigment near', 'concept_id': 'C4555503', 'confidence': 0.865685760974884}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}], [{'entity': 'hyperplastic epidermis', 'concept_id': 'C4748317', 'confidence': 0.7633129358291626}, {'entity': 'cellular infiltrate', 'concept_id': 'C1692321', 'confidence': 1.0}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_725",
"caption_rating": "8"
},
{
"": "1005118",
"caption": "The tumor appears to be well-circumscribed and has a blue staining due to hematoxylin staining the nucleus.",
"image_path": "8S4LeiO6Bbk_image_16dcef57-bfaa-4dd7-9077-d079e0cacb50.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['neoplastic process', 'blue tumor', 'nuclei', 'epithelial tumor', 'cribriform pattern']",
"noisy_text": " again, a very, very nice biopsy. Moving on to slide number three, we're changing directions here. Here we have several fragments of tissue and in looking at this, this is pretty clear that we're dealing with a neoplastic process. It's somewhat fragmented, but seems to be fairly well circumscribed. At scan, one can see that we've got a blue tumor or blue ball present here, and the blue staining is generally due to hematoxylin staining the nucleus. So we've got a lot of nuclei here that we'll want to take a look at. Overall, even though this is fragmented, the fact that it's fairly well circumscribed would indicate that it's got more of a benign silhouette. If we move to higher power, we can see that we're dealing with an epithelial rather than a mosaicable tumor. We've got interconnected cords and strands. We have somewhat of a ribiform pattern here, and",
"corrected_text": " again, a very, very nice biopsy. Moving on to slide number three, we're changing directions here. Here we have several fragments of tissue and in looking at this, this is pretty clear that we're dealing with a neoplastic process. It's somewhat fragmented, but seems to be fairly well circumscribed. At scan, one can see that we've got a blue tumor or blue ball present here, and the blue staining is generally due to hematoxylin staining the nucleus. So we've got a lot of nuclei here that we'll want to take a look at. Overall, even though this is fragmented, the fact that it's fairly well circumscribed would indicate that it's got more of a benign silhouette. If we move to higher power, we can see that we're dealing with an epithelial rather than a mesenchymal tumor. We've got interconnected cords and strands. We have somewhat of a cribriform pattern here, and",
"med_umls_ids": "[[{'entity': 'Neoplastic process', 'concept_id': 'C0027671', 'confidence': 1.0}, {'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'fragments', 'concept_id': 'C0332255', 'confidence': 1.0}], [{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'well-circumscribed', 'concept_id': 'C1707398', 'confidence': 0.9430561065673828}, {'entity': 'blue staining', 'concept_id': 'C0025746', 'confidence': 0.7925992608070374}, {'entity': 'hematoxylin staining', 'concept_id': 'C0018964', 'confidence': 0.9091285467147827}, {'entity': 'nucleus', 'concept_id': 'C0007610', 'confidence': 1.0}], [{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'epithelial', 'concept_id': 'C0221908', 'confidence': 1.0}, {'entity': 'mesenchymal origin', 'concept_id': 'C1513143', 'confidence': 0.8364232778549194}], [{'entity': 'Interconnected', 'concept_id': 'C0683595', 'confidence': 0.8500909209251404}, {'entity': 'cords', 'concept_id': 'C0034869', 'confidence': 0.801885187625885}, {'entity': 'strands', 'concept_id': 'C0600383', 'confidence': 0.800572395324707}, {'entity': 'cribriform pattern', 'concept_id': 'C1333163', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_726",
"caption_rating": "8"
},
{
"": "1004921",
"caption": "Intraglandular epithelial proliferation is a feature of high-grade dysplasia.",
"image_path": "r7OA0Trj5hQ_image_436dc006-96b9-4a0e-b164-b7df28969d1b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Stroma running in between', 'Crowded appearance', 'Back-to-back glands', 'Cribriform appearance', 'Intraglandular epithelial proliferation', 'Stroma running in between', 'Crowded appearance', 'Back-to-back glands', 'Cribriform appearance', 'Intraglandular epithelial proliferation']",
"noisy_text": " you can see some stroma running in between. However, it may be crowded. See here, one gland, another gland. You can see the nice stroma in between. These are back-to-back glands. But see here, this is one gland, this is one gland, this is one gland. But no stroma in between. So these are cribriform, which is intraglandular. Epithelial proliferation is happening within the gland, which is a future of high-grade dysplasia. So normal epithelium, low-grade dysplasia, high-grade dysplasia in one picture. Thanks to Google. I don't know the source, but I thank the person, anonymous person. So those are",
"corrected_text": " you can see some stroma running in between. However, it may be crowded. See here, one gland, another gland. You can see the nice stroma in between. These are back-to-back glands. But see here, this is one gland, this is one gland, this is one gland. But no stroma in between. So these are cribriform, which is intraglandular. Epithelial proliferation is happening within the gland, which is a future of high-grade dysplasia. So normal epithelium, low-grade dysplasia, high-grade dysplasia in one picture. Thanks to Google. I don't know the source, but I thank the person, anonymous person. So those are",
"med_umls_ids": "[[{'entity': 'Intraglandular', 'concept_id': 'C4725341', 'confidence': 0.9096097350120544}, {'entity': 'epithelial proliferation', 'concept_id': 'C0334097', 'confidence': 1.0}, {'entity': 'high-grade dysplasia', 'concept_id': 'C1333110', 'confidence': 0.8831341862678528}], [{'entity': 'Normal epithelium', 'concept_id': 'C0014609', 'confidence': 0.8199569582939148}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'dysplasia', 'concept_id': 'C0334044', 'confidence': 1.0}, {'entity': 'high-grade dysplasia', 'concept_id': 'C1333110', 'confidence': 0.8831341862678528}, {'entity': 'picture', 'concept_id': 'C0441468', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_727",
"caption_rating": "9"
},
{
"": "1004614",
"caption": "No necrosis or appreciable number of mitoses seen.",
"image_path": "8S4LeiO6Bbk_image_dda42eb4-663e-4e07-b885-a9a07e57b13b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "[]",
"noisy_text": " course, one can always do special stains, an iron stain, such as Prussian blue or pearls for hemocentaurant and a Fontanumus song stain for melanin pigment. So in any case, getting back to the to the lesion in question, we've got a lot of hemocentaurant-laden histiocytes here. We've also got, in other areas, fascicles, kind of randomly oriented of histiocytes and fibrocytes with oval and fusiform nuclei. There's a little bit of nuclear pleomorphism, but if you know, we're not seeing any necrosis or an appreciable number of mitotic figures. And this large cellular fibrohystic-acidic infiltrate, again with the collagen trapping and ring siderophages out",
"corrected_text": " course, one can always do special stains, an iron stain, such as Prussian blue or pearls for hemocyanin and a Fontana-Masson stain for melanin pigment. So in any case, getting back to the to the lesion in question, we've got a lot of hemocyanin-laden histiocytes here. We've also got, in other areas, fascicles, kind of randomly oriented of histiocytes and fibrocytes with oval and fusiform nuclei. There's a little bit of nuclear pleomorphism, but if you know, we're not seeing any necrosis or an appreciable number of mitoses. And this large cellular fibrohystic-acidic infiltrate, again with the collagen trapping and ring siderophages out",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'hemocyanin-laden histiocytes', 'concept_id': 'C0019612', 'confidence': 0.6349639296531677}, {'entity': 'fascicles', 'concept_id': 'C1185741', 'confidence': 1.0}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'fibrocytes', 'concept_id': 'C0225332', 'confidence': 0.9999999403953552}, {'entity': 'oval', 'concept_id': 'C1709367', 'confidence': 1.0}, {'entity': 'fusiform nuclei', 'concept_id': 'C0332493', 'confidence': 0.7332888245582581}], [{'entity': 'necrosis', 'concept_id': 'C0027540', 'confidence': 1.0}, {'entity': 'mitoses', 'concept_id': 'C0026255', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_728",
"caption_rating": "8"
},
{
"": "1006546",
"caption": "Intercommunicating slit-like vascular spaces in the mass.",
"image_path": "PJX3uZ7fRn4_image_f749ca24-e5b0-46f3-ac60-273091bcb4e3.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gynecologic', 'Soft tissue', 'Hematopathology']",
"roi_text": "['vascular channels', 'chorionic villi', 'calcification', 'vascular channels', 'chorionic villi', 'calcification']",
"noisy_text": " This is a section from placenta which shows a large irregular area with proliferation of thin walled vascular channels of variable size towards the fetal surface of placenta. Smaller chorionic villi can be seen towards the maternal site. Higher magnification of the same showing large vascular channels in the chorion filled with blood. Still higher magnification showing intercommunicating slit-like vascular spaces in the mass. Focal area of calcification can be seen in the tumor. Still another area",
"corrected_text": " This is a section from placenta which shows a large irregular area with proliferation of thin walled vascular channels of variable size towards the fetal surface of placenta. smaller chorionic villi are not incorrect can be seen towards the maternal site. Higher magnification of the same showing large vascular channels in the chorion filled with blood. Still higher magnification showing intercommunicating slit-like vascular spaces in the mass. Focal area of calcification can be seen in the tumor. Still another area",
"med_umls_ids": "[[{'entity': 'Proliferation', 'concept_id': 'C0334094', 'confidence': 1.0}, {'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}, {'entity': 'variable size', 'concept_id': 'C1866144', 'confidence': 0.8559831976890564}, {'entity': 'fetal', 'concept_id': 'C0015965', 'confidence': 1.0}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'placenta', 'concept_id': 'C0032043', 'confidence': 1.0}], [{'entity': 'chorionic villi', 'concept_id': 'C0008508', 'confidence': 1.0}, {'entity': 'maternal site', 'concept_id': 'C0026591', 'confidence': 0.7640593647956848}], [{'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}, {'entity': 'chorion', 'concept_id': 'C0008503', 'confidence': 0.9999998807907104}, {'entity': 'blood', 'concept_id': 'C0005767', 'confidence': 1.0}], [{'entity': 'Intercommunicating', 'concept_id': 'C0205196', 'confidence': 0.8271207213401794}, {'entity': 'vascular spaces', 'concept_id': 'C0225983', 'confidence': 0.819495439529419}, {'entity': 'mass', 'concept_id': 'C0577559', 'confidence': 1.0}], [{'entity': 'Focal area', 'concept_id': 'C0205234', 'confidence': 0.7634891271591187}, {'entity': 'calcification', 'concept_id': 'C0006660', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_729",
"caption_rating": "8"
},
{
"": "1004259",
"caption": "Follicular lymphoma has two different patterns: follicular and diffuse.",
"image_path": "udoW6VSqsm4_image_109d1109-ed46-44b8-ba02-cbdc8ac542bd.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['Follicular lymphoma', 'CD20', 'BCL6', 'follicle arrangement']",
"noisy_text": " and they often respond, you know, just an interracial steroid, local radiotherapy, some sort of excision. So, you know, this was follicle center cell lymphoma. There's one type that's comprised mostly of small lymphocytes, there's other types comprised mostly of the follicle cells. So there's the fuse, and then there's a follicular, there's kind of a mixed pattern. You don't need to know as much about this, but the way we work these up, they're strongly positive for CD20, and they're BCL6 positive in those follicle areas. And I like that kind of inside out follicle kind of arrangement. I think there's a photograph that kind of shows that. So these are the two different patterns, the follicular and the fuse, and then you can see the surrounding large neoplastic cells with the smaller lymphocytes. It's kind",
"corrected_text": " and they often respond, you know, just an interracial steroid, local radiotherapy, some sort of excision. So, you know, this was Follicular lymphoma. There's one type that's comprised mostly of small lymphocytes, there's other types comprised mostly of the follicle cells. So there's the fuse, and then there's a follicular, there's kind of a mixed pattern. You don't need to know as much about this, but the way we work these up, they're strongly positive for CD20, and they're BCL6 positive in those follicle areas. And I like that kind of inside out follicle kind of arrangement. I think there's a photograph that kind of shows that. So these are the two different patterns, the follicular and the fuse, and then you can see the surrounding large neoplastic cells with the smaller lymphocytes. It's kind",
"med_umls_ids": "[[{'entity': 'Follicular lymphoma', 'concept_id': 'C0024301', 'confidence': 1.0}, {'entity': 'treated with', 'concept_id': 'C0332293', 'confidence': 1.0}, {'entity': 'interracial', 'concept_id': 'C0682081', 'confidence': 0.9999999403953552}, {'entity': 'steroid', 'concept_id': 'C0038317', 'confidence': 1.0}, {'entity': 'local radiotherapy', 'concept_id': 'C0034619', 'confidence': 0.8772267699241638}, {'entity': 'excision', 'concept_id': 'C0015252', 'confidence': 1.0}], [{'entity': 'Follicular lymphoma', 'concept_id': 'C0024301', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'CD20', 'concept_id': 'C1417326', 'confidence': 1.0}, {'entity': 'BCL6', 'concept_id': 'C1332399', 'confidence': 1.0}, {'entity': 'follicle', 'concept_id': 'C0018120', 'confidence': 1.0}, {'entity': 'areas', 'concept_id': 'C0205146', 'confidence': 1.0}], [{'entity': 'Follicular lymphoma', 'concept_id': 'C0024301', 'confidence': 1.0}, {'entity': 'patterns', 'concept_id': 'C0449774', 'confidence': 1.0}, {'entity': 'follicular', 'concept_id': 'C0439682', 'confidence': 1.0}, {'entity': 'diffuse', 'concept_id': 'C0205219', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_730",
"caption_rating": "8"
},
{
"": "1005776",
"caption": "Presence of internal elastic lamina indicates artery, while its absence indicates vein.",
"image_path": "r7OA0Trj5hQ_image_f7991877-a8bd-4fb0-845b-ad94cceb8098.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " In high power, you can see very thick vessel wall with the narrowing of the lumen, whereas here, it is relatively preserved. So you want to know whether it is a vein or artery. Please believe me, this is a vein, and this is an artery. And that is proved by the elastic tissue strain. These are all pictures from Dr. Gonzalez's Twitter. And you can see here, there is no internal elastic lamina, whereas here, there is an internal elastic lamina. So this is a branch of mesenteric artery, whereas this is a branch of mesenteric vein. And there is a condition called as idiopathic myointimal hyperplasia of the mesenteric vein. I don't know how many of you have heard this company. There's a",
"corrected_text": " In high power, you can see very thick vessel wall with the narrowing of the lumen, whereas here, it is relatively preserved. So you want to know whether it is a vein or artery. Please believe me, this is a vein, and this is an artery. And that is proved by the elastic tissue strain. These are all pictures from Dr. Gonzalez's Twitter. And you can see here, there is no internal elastic lamina, whereas here, there is an internal elastic lamina. So this is a branch of mesenteric artery, whereas this is a branch of mesenteric vein. And there is a condition called as idiopathic myointimal hyperplasia of mesenteric vein of the mesenteric vein. I don't know how many of you have heard this company. There's a",
"med_umls_ids": "[[{'entity': 'Thick vessel wall', 'concept_id': 'C1180033', 'confidence': 0.6420797109603882}, {'entity': 'lumen', 'concept_id': 'C0524461', 'confidence': 0.9999998807907104}, {'entity': 'power', 'concept_id': 'C0032863', 'confidence': 1.0}], [{'entity': 'Identification', 'concept_id': 'C0020792', 'confidence': 1.0}, {'entity': 'vein', 'concept_id': 'C0042449', 'confidence': 1.0}, {'entity': 'artery', 'concept_id': 'C0003842', 'confidence': 1.0}, {'entity': 'elastic tissue', 'concept_id': 'C0013762', 'confidence': 1.0}, {'entity': 'strain', 'concept_id': 'C0080194', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'internal elastic lamina', 'concept_id': 'C1180561', 'confidence': 1.0}, {'entity': 'artery', 'concept_id': 'C0003842', 'confidence': 1.0}, {'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'vein', 'concept_id': 'C0042449', 'confidence': 1.0}], [{'entity': 'Branches', 'concept_id': 'C1182977', 'confidence': 0.7288598418235779}, {'entity': 'mesenteric artery', 'concept_id': 'C0025465', 'confidence': 1.0}, {'entity': 'vein', 'concept_id': 'C0042449', 'confidence': 1.0}, {'entity': 'examples', 'concept_id': 'C1707959', 'confidence': 0.8639216423034668}], [{'entity': 'Idiopathic myointimal hyperplasia', 'concept_id': 'C0333978', 'confidence': 0.8139097094535828}, {'entity': 'mesenteric vein', 'concept_id': 'C0025473', 'confidence': 1.0}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_731",
"caption_rating": "7"
},
{
"": "1008458",
"caption": "Clodin-1 is often expressed in perineuriomas, which can be a pitfall in diagnosis as it may resemble low-grade fibromyxoid sarcoma. Glut-1 is usually negative in perineuriomas but may be positive in rare cases of low-grade fibromyxoid sarcoma. MUC4 is a sensitive and specific marker for low-grade fibromyxoid sarcoma and should be negative in perineuriomas and DFSP.",
"image_path": "QDb68_G1HR4_image_40070839-9f02-485f-be7f-6f9363b416f6.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The one stain that was described a few years ago as being helpful here is called MUC4, M-U-C-4. MUC4 is in the setting of a fibroblastic spindle cell tumor like this, it is a very sensitive and specific marker at least as of today's date in 2018, so far it tends to be very sensitive and specific marker for low-grade fibromyxoid sarcoma and it should be negative in perineuriomas and DFSP and other entities in the differential diagnosis. Now I'm",
"corrected_text": " They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The one stain that was described a few years ago as being helpful here is called MUC4, M-U-C-4. MUC4 is in the setting of a fibroblastic spindle cell tumor like this, it is a very sensitive and specific marker at least as of today's date in 2018, so far it tends to be very sensitive and specific marker for low-grade fibromyxoid sarcoma and it should be negative in perineuriomas and DFSP and other entities in the differential diagnosis. Now I'm",
"med_umls_ids": "[[{'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}, {'entity': 'expressed', 'concept_id': 'C0017262', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'rare', 'concept_id': 'C0521114', 'confidence': 1.0}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'MUC4', 'concept_id': 'C1417496', 'confidence': 0.9999999403953552}, {'entity': 'sensitive', 'concept_id': 'C0020517', 'confidence': 1.0}, {'entity': 'marker', 'concept_id': 'C0005516', 'confidence': 0.9999999403953552}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_732",
"caption_rating": "10"
},
{
"": "1009059",
"caption": "Biopsy specimen shows infiltrate of lymphocytes and numerous melanophages in a patient with Erythema dyschromicum perstands (EDP), which is a variant of lichen planus. EDP lacks epidermal hyperplasia, hypergranulosis, compact orthokeratosis, and has a less robust inflammatory infiltrate compared to lichen planus. Clinical pathological correlation is important in diagnosing EDP.",
"image_path": "8S4LeiO6Bbk_image_294689bd-4e49-4997-bfe8-586a59c6a03a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['large hyperpigmented patches on the trunk extremities', 'subtle vacuolar change and melanophages within the papillary dermis', 'inflammatory infiltrate in Erythema multiforme is this significant or this robust, one usually sees many more necrotic keratinocytes in the epidermis', 'interface dermatitis', 'punch biopsy', 'inflammatory infiltrate in Erythema multiforme is this significant or this robust, one usually sees many more necrotic keratinocytes in the epidermis']",
"noisy_text": " infiltrate of lymphocytes and numerous melanovagias. And as it turns out, this biopsy specimen is from a Latin American individual with large hyperpigmented patches on the trunk extremities, and this was a biopsy of Erythema dyschromicum perstands, which is believed by most people to be a variant of Lycan planus, also sometimes goes by the name Lycan planus pigmentosus, is a much more subtle expression of Lycan planus than garden variety Lycan planus, lacks the epidermal hyperplasia, hypergranulosis, compact orthokeratosis, and the inflammatory infiltrate is usually much less robust. This is actually a pretty active inflammatory EDP. In late lesions of EDP, sometimes all you'll see is subtle bacular change and melanophagias within the papillary dermis. So, this is a condition where clinical pathological mission can be quite helpful. Without benefit of history, here the differential could conceivably include a drug eruption, Apache Lycanoid drug eruption, or even a Lycanoid photodermatitis, less likely a Lycanoid expression of connective tissue disease, but this biopsy was from a patient with EDP, and these are the types of changes one expects to see in that condition. One might also think briefly about Erythema multiforme because we've got bacular change, a basket we've quantified later, and lymphocytes. However, by the time the inflammatory infiltrate in Erythema multiforme is this significant or this robust, one usually sees many more necrotic keratinocytes in the epidermis. You could also think about a fixed drug eruption, but of course, in a fixed drug eruption, one would need to see eosinophils within the infiltrate, and they're absent in this particular case. Okay, let's go ahead and move on to slide number nine. This was another example of an interface dermatitis. We have a bisected punch biopsy here. This biopsy specimen was from the trunk and",
"corrected_text": " infiltrate of lymphocytes and numerous melanophages. And as it turns out, this biopsy specimen is from a Latin American individual with large hyperpigmented patches on the trunk extremities, and this was a biopsy of Erythema dyschromicum perstands, which is believed by most people to be a variant of lichen planus, also sometimes goes by the name lichen planus pigmentosus, is a much more subtle expression of Lycan planus than lichen planus, lacks the epidermal hyperplasia, hypergranulosis, compact orthokeratosis, and the inflammatory infiltrate is usually much less robust. This is actually a pretty active inflammatory EDP. In late lesions of EDP, sometimes all you'll see is subtle basal cell change and melanophagias within the papillary dermis. So, this is a condition where clinical pathological mission can be quite helpful. Without benefit of history, here the differential could conceivably include a drug eruption, Apache Lycanoid drug eruption, or even a lichenoid photodermatitis, less likely a Lycanoid expression of connective tissue disease, but this biopsy was from a patient with EDP, and these are the types of changes one expects to see in that condition. One might also think briefly about Erythema multiforme because we've got basal cell change, a basket we've quantified later, and lymphocytes. However, by the time the inflammatory infiltrate in Erythema multiforme is this significant or this robust, one usually sees many more necrotic keratinocytes in the epidermis. You could also think about a fixed drug eruption, but of course, in a fixed drug eruption, one would need to see eosinophils within the infiltrate, and they're absent in this particular case. Okay, let's go ahead and move on to slide number nine. This was another example of an interface dermatitis. We have a bisected punch biopsy here. This biopsy specimen was from the trunk and",
"med_umls_ids": "[[{'entity': 'Biopsy specimen', 'concept_id': 'C0677862', 'confidence': 1.0}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'numerous', 'concept_id': 'C0439064', 'confidence': 1.0}, {'entity': 'melanophages', 'concept_id': 'C3280463', 'confidence': 0.9375340938568115}, {'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'Erythema dyschromicum perstands', 'concept_id': 'C0263359', 'confidence': 0.9094144701957703}, {'entity': 'EDP', 'concept_id': 'C1098982', 'confidence': 0.7780879139900208}, {'entity': 'variant', 'concept_id': 'C0205419', 'confidence': 1.0}, {'entity': 'lichen planus', 'concept_id': 'C0023646', 'confidence': 1.0}, {'entity': 'EDP', 'concept_id': 'C1098982', 'confidence': 0.7780879139900208}, {'entity': 'epidermal hyperplasia', 'concept_id': 'C0263641', 'confidence': 1.0}, {'entity': 'hypergranulosis', 'concept_id': 'C3279547', 'confidence': 1.0}, {'entity': 'compact orthokeratosis', 'concept_id': 'C1843359', 'confidence': 0.8407344222068787}, {'entity': 'inflammatory infiltrate', 'concept_id': 'C3887644', 'confidence': 0.9999999403953552}, {'entity': 'lichen planus', 'concept_id': 'C0023646', 'confidence': 1.0}, {'entity': 'Clinical', 'concept_id': 'C0205210', 'confidence': 1.0}, {'entity': 'pathological', 'concept_id': 'C0030664', 'confidence': 1.0}, {'entity': 'correlation', 'concept_id': 'C1707520', 'confidence': 1.0}, {'entity': 'diagnosing', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'EDP', 'concept_id': 'C1098982', 'confidence': 0.7780879139900208}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_733",
"caption_rating": "9"
},
{
"": "1006927",
"caption": "Serous cyst papillary carcinoma is frequently associated with the presence of psammoma bodies, which are calcified rounded bodies.",
"image_path": "3mRB9j0eyVM_image_a564e201-b229-4bf5-9c1f-ede3903c371b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gynecologic', 'Hematopathology', 'Soft tissue']",
"roi_text": "['atypia', 'infiltrated the underlying stroma', 'solid looking tumor', 'lining epithelial cells', 'infiltrative pattern', 'malignant tumor', 'invasive pattern', 'calcified body', 'rounded calcified bodies', 'papillary configuration', 'papillary structures', 'psammoma bodies']",
"noisy_text": " they will they will be infiltrative pattern, invasive pattern of the tumor, solid looking tumor with you can see here again, pepillary structures are very clearly seen even in the here. This is the picture of serous cyst adenocarcinoma, why we are saying it is carcinoma? Because the lining epithelial cells they have these they have the characteristic feature of atypia, atypia we all know hyperchromatism, pleomorphism, atypical mitotic activity, high MC ratio all these features are seen in these cells along with infiltration. These cells they have infiltrated the underlying stroma, when they have infiltrated the underlying stroma we call this is a malignant tumor, this is serous cyst adenocarcinoma. Now we come to the most common presentation of the serous cyst adenocarcinoma that is pepillary. So most of these tumors they show pepillary configuration that is their cells the epithelial cells they are found in the they form the pepillary configuration and that pepillae then ultimately they invade and they result in the invasiveness. And we all know that the serous cyst pepillary carcinoma we these adenocarcinoma of the ovary this frequently is associated with presence of somoma bodies and what is somoma body you all know from your 3rd year lectures and it was very frequently asked in your viva questions also in your viva examination also that somoma body is a calcified body, rounded calcified bodies are the somoma bodies and these are the typical features or typical findings that are commonly seen in the pepillary serous cyst adenocarcinoma of the ovary. Now we come to the mucinous tumors, again the mucinous tumors are again categorized in mucinous",
"corrected_text": " they will they will be infiltrative pattern, invasive pattern of the tumor, solid looking tumor with you can see here again, papillary structures are very clearly seen even in the here. This is the picture of serous cyst adenocarcinoma, why we are saying it is carcinoma? Because the lining epithelial cells they have these they have the characteristic feature of atypia, atypia we all know hyperchromatism, pleomorphism, atypical mitotic activity, high MC ratio all these features are seen in these cells along with infiltration. These cells they have infiltrated the underlying stroma, when they have infiltrated the underlying stroma we call this is a malignant tumor, this is serous cyst adenocarcinoma. Now we come to the most common presentation of the serous cyst adenocarcinoma that is papillary. So most of these tumors they show papillary configuration that is their cells the epithelial cells they are found in the they form the papillary configuration and that papillae then ultimately they invade and they result in the invasiveness. And we all know that the serous cyst papillary carcinoma we these adenocarcinoma of the ovary this frequently is associated with presence of psammoma bodies and what is somoma body you all know from your 3rd year lectures and it was very frequently asked in your viva questions also in your viva examination also that somoma body is a calcified body, rounded calcified bodies are the psammoma bodies and these are the typical features or typical findings that are commonly seen in the papillary serous cyst adenocarcinoma of the ovary. Now we come to the mucinous tumors, again the mucinous tumors are again categorized in mucinous",
"med_umls_ids": "[[{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'infiltrative', 'concept_id': 'C4527217', 'confidence': 1.0}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}, {'entity': 'solid', 'concept_id': 'C0205208', 'confidence': 1.0}, {'entity': 'papillary structures', 'concept_id': 'C0030352', 'confidence': 0.7890171408653259}], [{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'serous cyst adenocarcinoma', 'concept_id': 'C0206701', 'confidence': 0.8984156847000122}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'atypia', 'concept_id': 'C0741302', 'confidence': 0.9999999403953552}, {'entity': 'infiltration', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'malignant behavior', 'concept_id': 'C0004927', 'confidence': 0.7649628520011902}], [{'entity': 'Papillary configuration', 'concept_id': 'C1276436', 'confidence': 0.9154161214828491}, {'entity': 'presentation', 'concept_id': 'C0449450', 'confidence': 1.0}, {'entity': 'serous cyst adenocarcinoma', 'concept_id': 'C0206701', 'confidence': 0.8984156847000122}], [{'entity': 'Serous cyst papillary carcinoma', 'concept_id': 'C3839184', 'confidence': 0.9130419492721558}, {'entity': 'associated with', 'concept_id': 'C0332281', 'confidence': 1.0}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'psammoma bodies', 'concept_id': 'C0391863', 'confidence': 1.0}, {'entity': 'calcified rounded bodies', 'concept_id': 'C0175895', 'confidence': 0.645065188407898}]]",
"magnification": "1.0",
"height": "720.0",
"width": "960.0",
"id": "test_734",
"caption_rating": "9"
},
{
"": "1008642",
"caption": "Presence of H. pylori in the luminal area or lumen of the stomach.",
"image_path": "r7OA0Trj5hQ_image_543a0feb-40d4-4b35-a6e4-da5a8bdec291.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['H. pylori in the luminal area or lumen', 'Neutrophils on the epithelium indicating active inflammation', 'H. pylori in the luminal area or lumen', 'Goblet cells in the surface epithelium.', 'Neutrophils on the epithelium indicating active inflammation', 'H. pylori in the luminal area or lumen', 'Goblet cells in the surface epithelium.']",
"noisy_text": " this is equivalent to cryptitis in the colon. In the stomach, we call it pit, so I don't want to call it pititis. It doesn't sound very great, but you can see the neutrophils sitting on the epithelium. So this is an active inflammation. Here, now we are coming to cytology. You see in the intra-luminal area or in the lumen, you see a lot of comma-shaped rods sitting on the epithelium, not going into the epithelium. So these are all the H. pylori in the oil immersion. Here, the surface epithelium shows goblet cells, and these are all biopsies",
"corrected_text": " this is equivalent to cryptitis in the colon. In the stomach, we call it pit, so I don't want to call it pititis. It doesn't sound very great, but you can see the neutrophils sitting on the epithelium. So this is an active inflammation. Here, now we are coming to cytology. You see in the luminal area or in the lumen, you see a lot of comma-shaped rods sitting on the epithelium, not going into the epithelium. So these are all the H. pylori in the oil immersion. Here, the surface epithelium shows goblet cells, and these are all biopsies",
"med_umls_ids": "[[{'entity': 'Active inflammation', 'concept_id': 'C0333361', 'confidence': 1.0}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'H. pylori', 'concept_id': 'C0079488', 'confidence': 1.0}, {'entity': 'luminal area', 'concept_id': 'C0524462', 'confidence': 0.7778207659721375}, {'entity': 'lumen', 'concept_id': 'C0524461', 'confidence': 0.9999998807907104}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}], [{'entity': 'Surface epithelium', 'concept_id': 'C1182809', 'confidence': 1.0}, {'entity': 'goblet cells', 'concept_id': 'C0506994', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_735",
"caption_rating": "8"
},
{
"": "1005704",
"caption": "The hamartoma involves both the epithelial component and a fibrous sheath around the hair follicle.",
"image_path": "LlPaENuqzVQ_image_5d534cab-1771-4c19-a157-83b1eaaf4f21.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['miniaturized hair follicle', 'mantle zone', 'stem cell area', 'bulge', 'apocrine gland', 'sebaceous gland', 'hamartoma', 'fibrous sheath', 'miniaturized hair follicle', 'mantle zone', 'stem cell area', 'bulge', 'apocrine gland', 'sebaceous gland', 'hamartoma', 'fibrous sheath']",
"noisy_text": " Like, it looks more like if there's, if I'm going to guess, like there's, I feel like there's a little bit of like, I would guess more like towards the, like a glandular. Yeah, well, it's, it's, it's a little miniaturized hair follicle. Nope. It's like this little guy here. It's like a little tiny follicle. And there's, we always think of three parts of the hair follicle. We think of the infundibulum, the isthmus, and we think of the inferior portion, but there's a very important part right around the isthmic part, just beneath the follicle, the infundibulum, and then where the inferior portion begins, that's known as the mantle zone. And that's kind of where all the action is. That's really kind of a stem cell area that sometimes those cells will form a little bulge there and they actually will end up forming an apocrine gland. Sometimes they'll end up forming a sebaceous gland. Sometimes they, you know, will just, they'll form, sometimes they form a little hammertoma, like you see right here. And they actually end up getting you this little sort of primitive little, it almost looks like a mini hair follicle that didn't really form. And then when you look at a hair follicle, it's comprised not only of the epithelial component, but there's also a periepithelial sheath around it, a fibrous sheath around the hair follicle. And so this is a hammertoma that involves both of those. So it's got a fibrous element to it. And then",
"corrected_text": " Like, it looks more like if there's, if I'm going to guess, like there's, I feel like there's a little bit of like, I would guess more like towards the, like a glandular. Yeah, well, it's, it's, it's a little miniaturized hair follicle. Nope. It's like this little guy here. It's like a little tiny follicle. And there's, we always think of three parts of the hair follicle. We think of the infundibulum, the isthmus, and we think of the inferior portion, but there's a very important part right around the isthmic part, just beneath the follicle, the infundibulum, and then where the inferior portion begins, that's known as the mantle zone. And that's kind of where all the action is. That's really kind of a stem cell area that sometimes those cells wiform a little bulge there and they actually wiend up forming an apocrine gland. Sometimes they'end up forming a sebaceous gland. Sometimes they, you know, will just, they'form, sometimes they form a little hamartoma, like you see right here. And they actually end up getting you this little sort of primitive little, it almost looks like a mini hair follicle that didn't really form. And then when you look at a hair follicle, it's comprised not only of the epithelial component, but there's also a periepithelial sheath around it, a fibrous sheath around the hair follicle. And so this is a hamartoma that involves both of those. So it's got a fibrous element to it. And then",
"med_umls_ids": "[[{'entity': 'narrator', 'concept_id': 'C1135957', 'confidence': 0.7711340188980103}, {'entity': 'miniaturized', 'concept_id': 'C0872350', 'confidence': 0.8111259341239929}, {'entity': 'hair follicle', 'concept_id': 'C0221971', 'confidence': 1.0}, {'entity': 'stem cell', 'concept_id': 'C0038250', 'confidence': 1.0}, {'entity': 'mantle zone', 'concept_id': 'C1512987', 'confidence': 1.0}], [{'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'mantle', 'concept_id': 'C0232445', 'confidence': 0.8497024178504944}, {'entity': 'zone', 'concept_id': 'C1710706', 'confidence': 1.0}, {'entity': 'bulge', 'concept_id': 'C0038999', 'confidence': 0.9999999403953552}, {'entity': 'apocrine gland', 'concept_id': 'C0003584', 'confidence': 0.9999998807907104}, {'entity': 'sebaceous gland', 'concept_id': 'C0036505', 'confidence': 1.0}, {'entity': 'hamartoma', 'concept_id': 'C0018552', 'confidence': 0.9999999403953552}], [{'entity': 'hamartoma', 'concept_id': 'C0018552', 'confidence': 0.9999999403953552}, {'entity': 'epithelial component', 'concept_id': 'C1707933', 'confidence': 0.8783122897148132}, {'entity': 'fibrous sheath', 'concept_id': 'C1185724', 'confidence': 1.0}, {'entity': 'hair follicle', 'concept_id': 'C0221971', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_736",
"caption_rating": "9"
},
{
"": "1006121",
"caption": "Multilobulated growth and dense fibrosis are present in this tumor.",
"image_path": "j_rG5XPImFQ_image_5c9a737a-56a2-4890-a545-1645d40ff13e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Hematopathology', 'Breast pathology']",
"roi_text": "['multilobulated growth', 'dense fibrosis', 'giant cells', 'multilobulated growth', 'dense fibrosis', 'giant cells']",
"noisy_text": " Mitotic activity can be relatively high, but this on its own should not be concerning for malignant transformation. In this case, you could see that the giant cells were not numerous, and there was minimal hemosiderin deposition. To give you a better sense of the morphologic spectrum of this tumor, I'm going to show a couple more examples. In this example, we still have multilobulated growth and dense fibrosis. However, even at low power, you can see that the giant cells are larger and more numerous than the previous example.",
"corrected_text": " Mitotic activity can be relatively high, but this on its own should not be concerning for malignant transformation. In this case, you could see that the giant cells were not numerous, and there was minimal hemosiderin deposition. To give you a better sense of the morphologic spectrum of this tumor, I'm going to show a couple more examples. In this example, we still have multilobulated growth and dense fibrosis. However, even at low power, you can see that the giant cells are larger and more numerous than the previous example.",
"med_umls_ids": "[[{'entity': 'Mitotic activity', 'concept_id': 'C1334779', 'confidence': 1.0}, {'entity': 'malignant transformation', 'concept_id': 'C0287850', 'confidence': 0.8324378132820129}], [{'entity': 'Giant cells', 'concept_id': 'C0017526', 'confidence': 1.0}, {'entity': 'hemosiderin', 'concept_id': 'C0019113', 'confidence': 1.0}, {'entity': 'deposition', 'concept_id': 'C0333562', 'confidence': 1.0}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}], [{'entity': 'Multilobulated', 'concept_id': 'C4538849', 'confidence': 0.8302288055419922}, {'entity': 'growth', 'concept_id': 'C0018270', 'confidence': 1.0}, {'entity': 'dense fibrosis', 'concept_id': 'C0016059', 'confidence': 0.8111783862113953}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}], [{'entity': 'Giant cells', 'concept_id': 'C0017526', 'confidence': 1.0}, {'entity': 'larger', 'concept_id': 'C0549177', 'confidence': 1.0}, {'entity': 'numerous', 'concept_id': 'C0439064', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_737",
"caption_rating": "8"
},
{
"": "1007722",
"caption": "Spindle cell non-epithelial neoplasms include muscle and neural tumors.",
"image_path": "LlPaENuqzVQ_image_dc777b8f-901a-4667-8033-74f2a1b61897.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['smooth muscle', 'skeletal muscle', 'spindle cell non-epithelial neoplasms', 'atypical fibroxanthoma', 'neural tumors', 'smooth muscle', 'skeletal muscle', 'spindle cell non-epithelial neoplasms', 'atypical fibroxanthoma', 'neural tumors']",
"noisy_text": " So basically, just to kind of go backwards, more generic, muscle. Yeah. Do it. OK. And then there's two types of muscle, right? There's smooth muscle, or three, cardiac muscle, hopefully, to see that in the skin. But smooth and skeletal muscle, which we hardly ever see skeletal muscle neoplasms in dermatology. So it's almost always smooth muscle when we're looking at muscle. And there's probably really only two or three spindle cell non-epithelial neoplasms you need to know about. So muscle's one. What are the other two, basically? Like AFX? Yeah, but more generic. So what's the differentiation in an atypical fibrous anthoma? Just think of the cells that have become malignant in that. They're obviously not muscle cells. Neural? Neural's the other one. Those are the three major ones. But the one that you're missing is the center one there. What else lives in your dermis normally here? So we're going to go back. Fibroblast. Yeah,",
"corrected_text": " So basically, just to kind of go backwards, more generic, muscle. Yeah. Do it. OK. And then there's two types of muscle, right? There's smooth muscle, or three, cardiac muscle, hopefully, to see that in the skin. But smooth and skeletal muscle, which we hardly ever see skeletal muscle neoplasms in dermatology. So it's almost always smooth muscle when we're looking at muscle. And there's probably really only two or three spindle cell non-epithelial neoplasms you need to know about. So muscle's one. What are the other two, basically? Like AFX? Yeah, but more generic. So what's the differentiation in an atypical fibroxanthoma? Just think of the cells that have become malignant in that. They're obviously not muscle cells. Neural? Neural's the other one. Those are the three major ones. But the one that you're missing is the center one there. What else lives in your dermis normally here? So we're going to go back. Fibroblast. Yeah,",
"med_umls_ids": "[[{'entity': 'Smooth', 'concept_id': 'C0205357', 'confidence': 1.0}, {'entity': 'skeletal muscle', 'concept_id': 'C0242692', 'confidence': 1.0}, {'entity': 'muscle', 'concept_id': 'C0026845', 'confidence': 1.0}, {'entity': 'smooth muscle', 'concept_id': 'C1267092', 'confidence': 1.0}, {'entity': 'dermatology', 'concept_id': 'C0011627', 'confidence': 1.0}], [{'entity': 'Spindle cell', 'concept_id': 'C0682540', 'confidence': 0.9999999403953552}, {'entity': 'non-epithelial neoplasms', 'concept_id': 'C1368683', 'confidence': 0.8066584467887878}, {'entity': 'muscle', 'concept_id': 'C0026845', 'confidence': 1.0}, {'entity': 'neural tumors', 'concept_id': 'C1334956', 'confidence': 0.849646270275116}], [{'entity': 'Atypical fibroxanthoma', 'concept_id': 'C0346053', 'confidence': 1.0}, {'entity': 'malignant tumor', 'concept_id': 'C0006826', 'confidence': 1.0}, {'entity': 'muscle cells', 'concept_id': 'C0596981', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_738",
"caption_rating": "8"
},
{
"": "1005099",
"caption": "The pattern is consistent with superficial and deep funiculitis, involving the perivascular and interstitial regions.",
"image_path": "udoW6VSqsm4_image_51baed9e-eb48-4081-8853-ae258746f29c.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " Okay, so here we have a punch biopsy, non-equal skin. What we can see is there is a more sparse, moderate, and full trait in the superficial and deep dermis, and into the fat as well. And there's some eosinophilic component to it as well. Okay, what's the overall pattern? It's probably a superficial and deep, almost like a little funiculitis. It does go into the fat, and perivascular and interstitial. Yeah, and interstitial. And notice that there's no epidermal involved. No, epidermis is completely sparse. Even higher magnification. Now what do you see? Now I",
"corrected_text": " Okay, so here we have a punch biopsy, non-equal skin. What we can see is there is a more sparse, moderate, and full trait in the superficial and deep dermis, and into the fat as well. And there's some eosinophilic component to it as well. Okay, what's the overall pattern? It's probably a superficial and deep, almost like a little funiculitis. It does go into the fat, and perivascular and interstitial. Yeah, and interstitial. And notice that there's no epidermal involved. No, epidermis is completely sparse. Even higher magnification. Now what do you see? Now I",
"med_umls_ids": "[[{'entity': 'Punch biopsy', 'concept_id': 'C0182557', 'confidence': 1.0}, {'entity': 'normal skin', 'concept_id': 'C0558145', 'confidence': 1.0}, {'entity': 'moderate', 'concept_id': 'C0205081', 'confidence': 1.0}, {'entity': 'trait', 'concept_id': 'C0599883', 'confidence': 1.0}, {'entity': 'superficial', 'concept_id': 'C0205124', 'confidence': 1.0}, {'entity': 'deep dermis', 'concept_id': 'C0205125', 'confidence': 0.7651135921478271}, {'entity': 'fat', 'concept_id': 'C0015677', 'confidence': 1.0}], [{'entity': 'eosinophilic', 'concept_id': 'C0333930', 'confidence': 1.0}, {'entity': 'component', 'concept_id': 'C0449432', 'confidence': 1.0}, {'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}], [{'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}, {'entity': 'consistent with', 'concept_id': 'C0332290', 'confidence': 1.0}, {'entity': 'superficial', 'concept_id': 'C0205124', 'confidence': 1.0}, {'entity': 'deep funiculitis', 'concept_id': 'C0241216', 'confidence': 0.7899089455604553}, {'entity': 'perivascular', 'concept_id': 'C0442165', 'confidence': 1.0}, {'entity': 'interstitial regions', 'concept_id': 'C0596790', 'confidence': 0.7848911285400391}], [{'entity': 'involvement', 'concept_id': 'C1314939', 'confidence': 1.0}, {'entity': 'epidermis', 'concept_id': 'C0014520', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_739",
"caption_rating": "10"
},
{
"": "1005031",
"caption": "Perforating GA is a type of granulomatous condition that gives palisade granulostermatitis.",
"image_path": "udoW6VSqsm4_image_30d935c5-5d59-43aa-93d8-cd7cd7b0e1af.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['small individual papules', 'central crust', 'perioral skin', 'granulomatous condition', 'palisade granulostermatitis', 'neutrophilic dermatosis', 'older individuals', 'perineoplastic process']",
"noisy_text": " Yeah, this would be more kind of the classic one, probably. What else? Here's the classic one clinically. What if there's small individual papules that have a central crust in them, often on apral skin? We have had several cases of the disseminated GA, but I'm not sure if they didn't have a crust. So, what's the type that had it? Perforating? Perforating GA. Perforating GA, good. So, this was granulomanuary. There's one other condition that gives you palisade granulostermatitis like this, but it also gives you some neutrophils infiltrate. That palisade and neutrophilic granulostermatitis, that's another thing that you at least have to think about when you see GA. If you see an older person that's got disseminated GA, think about it as a perineoplastic process. Sometimes you",
"corrected_text": " Yeah, this would be more kind of the classic one, probably. What else? Here's the classic one clinically. What if there's small individual papules that have a central crust in them, often on perioral skin? We have had several cases of the disseminated GA, but I'm not sure if they didn't have a crust. So, what's the type that had it? Perforating? Perforating GA. Perforating GA, good. So, this was granulomatous. There's one other condition that gives you palisade granulostermatitis like this, but it also gives you some neutrophils infiltrate. That palisade and neutrophilic dermatosis, that's another thing that you at least have to think about when you see GA. If you see an older person that's got disseminated GA, think about it as a perineoplastic process. Sometimes you",
"med_umls_ids": "[[{'entity': 'Clinical', 'concept_id': 'C0205210', 'confidence': 1.0}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'skin condition', 'concept_id': 'C1719933', 'confidence': 1.0}, {'entity': 'individual', 'concept_id': 'C0027361', 'confidence': 1.0}, {'entity': 'papules', 'concept_id': 'C0332563', 'confidence': 0.9999999403953552}, {'entity': 'central crust', 'concept_id': 'C0205204', 'confidence': 0.7633819580078125}, {'entity': 'perioral skin', 'concept_id': 'C0448802', 'confidence': 0.8075158596038818}], [{'entity': 'Perforating', 'concept_id': 'C0549099', 'confidence': 1.0}, {'entity': 'GA', 'concept_id': 'C0002915', 'confidence': 1.0}, {'entity': 'granulomatous condition', 'concept_id': 'C0439667', 'confidence': 0.8219265341758728}, {'entity': 'palisade', 'concept_id': 'C0331512', 'confidence': 0.8241410255432129}, {'entity': 'granulostermatitis', 'concept_id': 'C0743086', 'confidence': 0.7311265468597412}], [{'entity': 'Neutrophilic dermatosis', 'concept_id': 'C1142272', 'confidence': 1.0}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'GA', 'concept_id': 'C0002915', 'confidence': 1.0}], [{'entity': 'Disseminated', 'concept_id': 'C0205221', 'confidence': 1.0}, {'entity': 'GA', 'concept_id': 'C0002915', 'confidence': 1.0}, {'entity': 'older', 'concept_id': 'C0337524', 'confidence': 0.7771234512329102}, {'entity': 'individuals', 'concept_id': 'C0027361', 'confidence': 0.8766164779663086}, {'entity': 'perineoplastic process', 'concept_id': 'C0027671', 'confidence': 0.8771522045135498}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_740",
"caption_rating": "7"
},
{
"": "1008394",
"caption": "Inflammatory bowel disease is not likely based on the cytology.",
"image_path": "sDFjOtMAYrk_image_c28373d3-b282-46d8-b6be-d50cd5854b00.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['prominent nucleoli', 'reactive cytologic atypia', 'chemotherapy or radiation', 'cancer', 'inflammatory bowel disease', 'prominent nucleoli', 'reactive cytologic atypia', 'chemotherapy or radiation', 'cancer', 'inflammatory bowel disease']",
"noisy_text": " I'm missing it. Okay. I think what's catching my eye for the most part is the prominent nucleolide, but what would you say about the NC ratio? Yeah, I think overall it's low. You have lots, loads of cytoplasm. Even though the nuclei are big, you have loads of cytoplasm. So, with this morphology, first of all, the question was, you know, inflammatory bowel disease. Okay, maybe, but the cytology is not great for the degree of reactive epithelial changes. Although you can have some crazy looking inflammatory bowel disease cases, it's really crazy. When I see crazy bizarre epithelial atypia, I think about treatment effect, either chemotherapy or radiation. Both of them can give you this crazy cytologic atypia that sometimes may actually make you think of cancer. We've got a couple of cases received in consultation. I'm remembering one specifically in the stomach where the question is, what about this cancer? And it wasn't. It was just crazy reactive epithelial changes in a patient who we didn't know, but the patient had received radiotherapy for lung cancer. And it definitely looked a lot like malignancy, but there was something not right about it. So, this patient was receiving at the same time chemotherapy for his pancreatic cancer. One thing you can see in patients, especially when they're receiving radiation,",
"corrected_text": " I'm missing it. Okay. I think what's catching my eye for the most part is the prominent nucleoli, but what would you say about the NC ratio? Yeah, I think overall it's low. You have lots, loads of cytoplasm. Even though the nuclei are big, you have loads of cytoplasm. So, with this morphology, first of all, the question was, you know, inflammatory bowel disease. Okay, maybe, but the cytology is not great for the degree of reactive epithelial changes. Although you can have some crazy looking inflammatory bowel disease cases, it's really crazy. When I see crazy bizarre epithelial atypia, I think about treatment effect, either chemotherapy or radiation. Both of them can give you this reactive cytologic atypia that sometimes may actually make you think of cancer. We've got a couple of cases received in consultation. I'm remembering one specifically in the stomach where the question is, what about this cancer? And it wasn't. It was just crazy reactive epithelial changes in a patient who we didn't know, but the patient had received radiotherapy for lung cancer. And it definitely looked a lot like malignancy, but there was something not right about it. So, this patient was receiving at the same time chemotherapy for his pancreatic cancer. One thing you can see in patients, especially when they're receiving radiation,",
"med_umls_ids": "[[{'entity': 'Prominent', 'concept_id': 'C0205402', 'confidence': 0.9999999403953552}, {'entity': 'nucleoli', 'concept_id': 'C0007609', 'confidence': 0.8710004091262817}, {'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'NC', 'concept_id': 'C0027964', 'confidence': 1.0}, {'entity': 'ratio', 'concept_id': 'C0456603', 'confidence': 1.0}, {'entity': 'low', 'concept_id': 'C0205251', 'confidence': 0.9999999403953552}], [{'entity': 'Reactive cytologic atypia', 'concept_id': 'C0333865', 'confidence': 0.8587049245834351}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'treatment effect', 'concept_id': 'C1518681', 'confidence': 1.0}, {'entity': 'chemotherapy', 'concept_id': 'C0013216', 'confidence': 1.0}, {'entity': 'radiation', 'concept_id': 'C0034519', 'confidence': 1.0}], [{'entity': 'Crazy', 'concept_id': 'C0424157', 'confidence': 0.6988691687583923}, {'entity': 'cancer', 'concept_id': 'C0006826', 'confidence': 0.9999998807907104}], [{'entity': 'Inflammatory bowel disease', 'concept_id': 'C0021390', 'confidence': 1.0}, {'entity': 'cytology', 'concept_id': 'C0010818', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_741",
"caption_rating": "8"
},
{
"": "1004603",
"caption": "Punch biopsy reveals nodular angioplasia in the papillary dermis.",
"image_path": "hoV-JkD6Wb0_image_a9954815-75a0-4513-ac9c-cf559c4e861d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['Lesion with induration and yellow periphery', 'Nodular angioplasia in the papillary dermis', 'Septal and lobular panniculitis', 'Distortion of fat architecture', 'Stasis-related vascular change', 'Subcutaneous tissue with few viable adipocytes', 'Lesion with induration and yellow periphery', 'Nodular angioplasia in the papillary dermis', 'Septal and lobular panniculitis', 'Distortion of fat architecture', 'Stasis-related vascular change', 'Subcutaneous tissue with few viable adipocytes']",
"noisy_text": " injurated, looks a little yellow over at the periphery, a little red center light, and a large punch biopsy through this lesion reveals evidence within the papillary dermis of nodular angioplasia, so we have a little bit of stasis-related vascular change, but not much inflammation. In this particular instance, we have a rip-roaring paniculitis here. We have a lobular paniculitis. If you take a look at the fat here, there's total distortion of the architecture, and this is barely discernible as subcutaneous tissue, but there's not a lot of inflammation. There aren't many viable adipocytes left here. A lot of the adipocytes have kind of ruptured and fused,",
"corrected_text": " indurated, looks a little yellow over at the periphery, a little red center light, and a large punch biopsy through this lesion reveals evidence within the papillary dermis of nodular angioplasia, so we have a little bit of stasis-related vascular change, but not much inflammation. In this particular instance, we have a lobular panniculitis here. We have a lobular panniculitis. If you take a look at the fat here, there's total distortion of the architecture, and this is barely discernible as subcutaneous tissue, but there's not a lot of inflammation. There aren't many viable adipocytes left here. A lot of the adipocytes have kind of ruptured and fused,",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'indurated', 'concept_id': 'C0702114', 'confidence': 1.0}, {'entity': 'yellow periphery', 'concept_id': 'C0221205', 'confidence': 0.7174375653266907}, {'entity': 'red center light', 'concept_id': 'C0563227', 'confidence': 0.7959515452384949}], [{'entity': 'Punch biopsy', 'concept_id': 'C0182557', 'confidence': 1.0}, {'entity': 'nodular angioplasia', 'concept_id': 'C0205297', 'confidence': 0.6163609623908997}, {'entity': 'papillary dermis', 'concept_id': 'C0682598', 'confidence': 1.0}], [{'entity': 'Septal', 'concept_id': 'C0442004', 'confidence': 0.9999999403953552}, {'entity': 'lobular panniculitis', 'concept_id': 'C0263012', 'confidence': 1.0}, {'entity': 'distortion', 'concept_id': 'C0332482', 'confidence': 1.0}, {'entity': 'fat architecture', 'concept_id': 'C0003737', 'confidence': 0.88345867395401}], [{'entity': 'stasis-related vascular change', 'concept_id': 'C0005847', 'confidence': 0.522698700428009}, {'entity': 'inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}], [{'entity': 'adipocytes', 'concept_id': 'C0206131', 'confidence': 1.0}, {'entity': 'left', 'concept_id': 'C0205091', 'confidence': 1.0}, {'entity': 'subcutaneous tissue', 'concept_id': 'C0222331', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_742",
"caption_rating": "8"
},
{
"": "1007796",
"caption": "The narrator describes a miniaturized hair follicle with a stem cell area known as the mantle zone.",
"image_path": "LlPaENuqzVQ_image_40616c81-7aed-4be5-9936-764c914b067e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['miniaturized hair follicle', 'mantle zone', 'stem cell area', 'bulge', 'apocrine gland', 'sebaceous gland', 'hamartoma', 'fibrous sheath']",
"noisy_text": " Like, it looks more like if there's, if I'm going to guess, like there's, I feel like there's a little bit of like, I would guess more like towards the, like a glandular. Yeah, well, it's, it's, it's a little miniaturized hair follicle. Nope. It's like this little guy here. It's like a little tiny follicle. And there's, we always think of three parts of the hair follicle. We think of the infundibulum, the isthmus, and we think of the inferior portion, but there's a very important part right around the isthmic part, just beneath the follicle, the infundibulum, and then where the inferior portion begins, that's known as the mantle zone. And that's kind of where all the action is. That's really kind of a stem cell area that sometimes those cells will form a little bulge there and they actually will end up forming an apocrine gland. Sometimes they'll end up forming a sebaceous gland. Sometimes they, you know, will just, they'll form, sometimes they form a little hammertoma, like you see right here. And they actually end up getting you this little sort of primitive little, it almost looks like a mini hair follicle that didn't really form. And then when you look at a hair follicle, it's comprised not only of the epithelial component, but there's also a periepithelial sheath around it, a fibrous sheath around the hair follicle. And so this is a hammertoma that involves both of those. So it's got a fibrous element to it. And then",
"corrected_text": " Like, it looks more like if there's, if I'm going to guess, like there's, I feel like there's a little bit of like, I would guess more like towards the, like a glandular. Yeah, well, it's, it's, it's a little miniaturized hair follicle. Nope. It's like this little guy here. It's like a little tiny follicle. And there's, we always think of three parts of the hair follicle. We think of the infundibulum, the isthmus, and we think of the inferior portion, but there's a very important part right around the isthmic part, just beneath the follicle, the infundibulum, and then where the inferior portion begins, that's known as the mantle zone. And that's kind of where all the action is. That's really kind of a stem cell area that sometimes those cells wiform a little bulge there and they actually wiend up forming an apocrine gland. Sometimes they'end up forming a sebaceous gland. Sometimes they, you know, will just, they'form, sometimes they form a little hamartoma, like you see right here. And they actually end up getting you this little sort of primitive little, it almost looks like a mini hair follicle that didn't really form. And then when you look at a hair follicle, it's comprised not only of the epithelial component, but there's also a periepithelial sheath around it, a fibrous sheath around the hair follicle. And so this is a hamartoma that involves both of those. So it's got a fibrous element to it. And then",
"med_umls_ids": "[[{'entity': 'narrator', 'concept_id': 'C1135957', 'confidence': 0.7711340188980103}, {'entity': 'miniaturized', 'concept_id': 'C0872350', 'confidence': 0.8111259341239929}, {'entity': 'hair follicle', 'concept_id': 'C0221971', 'confidence': 1.0}, {'entity': 'stem cell', 'concept_id': 'C0038250', 'confidence': 1.0}, {'entity': 'mantle zone', 'concept_id': 'C1512987', 'confidence': 1.0}], [{'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'mantle', 'concept_id': 'C0232445', 'confidence': 0.8497024178504944}, {'entity': 'zone', 'concept_id': 'C1710706', 'confidence': 1.0}, {'entity': 'bulge', 'concept_id': 'C0038999', 'confidence': 0.9999999403953552}, {'entity': 'apocrine gland', 'concept_id': 'C0003584', 'confidence': 0.9999998807907104}, {'entity': 'sebaceous gland', 'concept_id': 'C0036505', 'confidence': 1.0}, {'entity': 'hamartoma', 'concept_id': 'C0018552', 'confidence': 0.9999999403953552}], [{'entity': 'hamartoma', 'concept_id': 'C0018552', 'confidence': 0.9999999403953552}, {'entity': 'epithelial component', 'concept_id': 'C1707933', 'confidence': 0.8783122897148132}, {'entity': 'fibrous sheath', 'concept_id': 'C1185724', 'confidence': 1.0}, {'entity': 'hair follicle', 'concept_id': 'C0221971', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_743",
"caption_rating": "7"
},
{
"": "1004509",
"caption": "Description of pancreatic acinar metaplasia in the stomach and small intestine.",
"image_path": "r7OA0Trj5hQ_image_2310b77e-9111-4a96-98ef-680e62280e5d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['acinar structures resembling pancreas', 'pancreatic acinar-like structures in the GIT', 'acinar structures resembling pancreas', 'pancreatic acinar-like structures in the GIT']",
"noisy_text": " Sometimes the stomach can show acinar structures resembling pancreas. Then it is known as pancreatic acinar metaplasia. This can also happen in the small intestine. There, when you do staining for amylase or trypsin, it will be positive, but on H&E itself, you can see pancreatic acinar-like structures in the GIT. Then it will become pancreatic acinar metaplasia. Here is the best example of atrophy. Again, unfortunately, there is no defined number of glands to be seen because this is age-dependentation, size-dependentation, race-dependent. So",
"corrected_text": " Sometimes the stomach can show acinar structures resembling pancreas. Then it is known as pancreatic acinar metaplasia. This can also happen in the small intestine. There, when you do staining for amylase or trypsin, it will be positive, but on H&E itself, you can see pancreatic acinar-like structures in the GIT. Then it will become pancreatic acinar metaplasia. Here is the best example of atrophy. Again, unfortunately, there is no defined number of glands to be seen because this is age-dependentation, size-dependentation, race-dependent. So",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'pancreatic acinar metaplasia', 'concept_id': 'C4021967', 'confidence': 0.7844848036766052}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'small intestine', 'concept_id': 'C0021852', 'confidence': 1.0}], [{'entity': 'Staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'amylase', 'concept_id': 'C0002712', 'confidence': 1.0}, {'entity': 'trypsin', 'concept_id': 'C0041236', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'intestine', 'concept_id': 'C0021853', 'confidence': 1.0}], [{'entity': 'atrophy', 'concept_id': 'C0333641', 'confidence': 1.0}, {'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'age', 'concept_id': 'C0001779', 'confidence': 1.0}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'dependence', 'concept_id': 'C0011546', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_744",
"caption_rating": "7"
},
{
"": "1008276",
"caption": "The glands and epithelium are pushed apart from each other, which may be procedure-related or seen in chemical gastritis.",
"image_path": "r7OA0Trj5hQ_image_12588514-8bd8-4cc3-b1a3-05e9f8138c11.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Muscle coming in the lamina propria', 'Muscularis mucosa is hyperplastic', 'Muscle coming in the lamina propria', 'Muscularis mucosa is hyperplastic', 'Muscle coming in the lamina propria', 'Muscularis mucosa is hyperplastic']",
"noisy_text": " The epithelium, the glands are pushed apart each other. And this may be procedure related. This may be seen in chemical gastritis, lamina propria. It's a very nonspecific finding, not diagnostic of anything. But whenever you see, think of chemical gastritis. This is muscularization. You see in the hyperwire, muscle coming in the lamina propria. Lamina propria should be free of musculature. The muscle should be there only in the muscularis mucosa. Here in this low power, you can see the muscularis mucosa is hyperplastic. And it is sending the muscle bundle into the lamina propria. This happens in chemical gastritis in case of stomach and in",
"corrected_text": " The epithelium, the glands are pushed apart each other. And this may be procedure related. This may be seen in chemical gastritis, lamina propria. It's a very nonspecific finding, not diagnostic of anything. But whenever you see, think of chemical gastritis. This is muscularization. You see in the hyperplasia, muscle coming in the lamina propria. Lamina propria should be free of musculature. The muscle should be there only in the muscularis mucosa. Here in this low power, you can see the muscularis mucosa is hyperplastic. And it is sending the muscle bundle into the lamina propria. This happens in chemical gastritis in case of stomach and in",
"med_umls_ids": "[[{'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'procedure-related', 'concept_id': 'C2924519', 'confidence': 1.0}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}], [{'entity': 'Muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'nonspecific', 'concept_id': 'C0750540', 'confidence': 1.0}, {'entity': 'finding', 'concept_id': 'C0037088', 'confidence': 1.0}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}], [{'entity': 'Muscle', 'concept_id': 'C0026845', 'confidence': 1.0}, {'entity': 'muscularis mucosa', 'concept_id': 'C0225357', 'confidence': 0.9999998807907104}, {'entity': 'hyperplasia', 'concept_id': 'C0020507', 'confidence': 1.0}, {'entity': 'muscle bundles', 'concept_id': 'C0504095', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}], [{'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_745",
"caption_rating": "8"
},
{
"": "1005443",
"caption": "Characteristic morphology of myofibroblasts.",
"image_path": "j_rG5XPImFQ_image_6da69d48-a359-4580-bf7d-0ccdf5b83e5b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Hematopathology', 'Breast pathology']",
"roi_text": "['nucleolus', 'myofibroblasts', 'myositis ossificans']",
"noisy_text": " nucleolus, and a moderate amount of amphiphilic cytoplasm. Now, at first glance, you might think these cells look a bit weird, and that might make you worry about a sarcoma, such as osteosarcoma. However, you'll come to recognize that this pattern in morphology you see here is really characteristic of myofibroblasts. This is an example of myocytosocificans, a benign myofibroblastic neoplasm that is part of the USP6 rearranged family of tumors, which includes, among others, nodular fasciitis and aneurysmal bone cyst. These are",
"corrected_text": " nucleolus, and a moderate amount of amphiphilic cytoplasm. Now, at first glance, you might think these cells look a bit weird, and that might make you worry about a sarcoma, such as osteosarcoma. However, you'll come to recognize that this pattern in morphology you see here is really characteristic of myofibroblasts. This is an example of myositis ossificans, a benign myofibroblastic neoplasm that is part of the USP6 rearranged family of tumors, which includes, among others, nodular fasciitis and aneurysmal bone cyst. These are",
"med_umls_ids": "[[{'entity': 'Moderate', 'concept_id': 'C0205081', 'confidence': 1.0}, {'entity': 'amount', 'concept_id': 'C1265611', 'confidence': 0.9999998807907104}, {'entity': 'amphiphilic', 'concept_id': 'C0596084', 'confidence': 0.8564908504486084}, {'entity': 'cytoplasm', 'concept_id': 'C0010834', 'confidence': 1.0}], [{'entity': 'Characteristic', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}, {'entity': 'myofibroblasts', 'concept_id': 'C0225360', 'confidence': 1.0}], [{'entity': 'Myositis ossificans', 'concept_id': 'C0027122', 'confidence': 0.9999999403953552}, {'entity': 'benign', 'concept_id': 'C0205183', 'confidence': 1.0}, {'entity': 'USP6', 'concept_id': 'C1175888', 'confidence': 1.0}, {'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_746",
"caption_rating": "8"
},
{
"": "1007330",
"caption": "The lesion appears neoplastic and epithelial in nature",
"image_path": "LlPaENuqzVQ_image_ef6a8cee-dc5d-48bc-89e3-5f6351cfba7e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['The lesion is not well circumscribed and appears asymmetrical', 'The size of the lesion is large', 'The lesion is not well circumscribed and appears asymmetrical']",
"noisy_text": " So they basically took the elliptical excision. They cut it into bread loaves and put it all on one slide. So that's how they did this in this case, because yeah, if you do a shave, how frequently do you get down to the bottom of the subcutaneous fat? That's pretty rare. So this is an excisional biopsy. Good. And are you dealing with an inflammatory or neoplastic process? Looks more neoplastic. Good, good. Epithelial or non-epithelial? Epithelioid. Good, epithelial. Benign or malignant? It's not very well prescribed. You can do it low power, isn't it? It's phenomenal. You can really get it down pretty well if you just apply the criteria. So you like benign or malignant here? It's not very well circumscribed, and it looks like there's some erosion on top. That may be from a prior biopsy, interestingly enough. But yeah, look at its symmetry. Is this symmetrical? Not really. No, no, no. It's pretty big. This is",
"corrected_text": " So they basically took the elliptical excision. They cut it into bread loaves and put it all on one slide. So that's how they did this in this case, because yeah, if you do a shave, how frequently do you get down to the bottom of the subcutaneous fat? That's pretty rare. So this is an excisional biopsy. Good. And are you dealing with an inflammatory or neoplastic process? Looks more neoplastic. Good, good. Epithelial or non-epithelial? epithelial. Good, epithelial. Benign or malignant? It's not very well prescribed. You can do it low power, isn't it? It's phenomenal. You can really get it down pretty well if you just apply the criteria. So you like benign or malignant here? It's not very well circumscribed, and it looks like there's some erosion on top. That may be from a prior biopsy, interestingly enough. But yeah, look at its symmetry. Is this symmetrical? Not really. No, no, no. It's pretty big. This is",
"med_umls_ids": "[[{'entity': 'Elliptical excision', 'concept_id': 'C1707902', 'confidence': 0.8901858329772949}, {'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}], [{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'neoplastic', 'concept_id': 'C1709160', 'confidence': 0.9999999403953552}, {'entity': 'epithelial', 'concept_id': 'C0221908', 'confidence': 1.0}], [{'entity': 'Malignancy', 'concept_id': 'C0006826', 'confidence': 1.0}, {'entity': 'determined with', 'concept_id': 'C0521095', 'confidence': 0.8590028285980225}, {'entity': 'certainty', 'concept_id': 'C0205423', 'confidence': 1.0}], [{'entity': 'erosion', 'concept_id': 'C0333307', 'confidence': 1.0}, {'entity': 'top', 'concept_id': 'C1420726', 'confidence': 1.0}, {'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_747",
"caption_rating": "8"
},
{
"": "1004578",
"caption": "Pseudomembranes can be caused by Clostridioides difficile colitis or ischemic injury.",
"image_path": "sDFjOtMAYrk_image_0887edbf-5f48-4747-8342-2d4f7a6e89b5.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['Clostridioides difficile colitis', 'lamina propria', 'hyalinization', 'Clostridioides difficile colitis', 'lamina propria', 'hyalinization']",
"noisy_text": " will give you pseudomembranes. Ischemic injury can also give it to you. And the one thing to note is that, so this patient had C. difficile colitis by laboratory, but he was not responding to treatment and they just decided to take a biopsy. And you can see here that in the lamina propria is not hyalinized. Now, does that mean that ischemia is excluded? No, because if it's, you know, it depends on the clinical history. If it's recent ischemia that happened within, I don't know, 24, 48 hours, you know, the hyalinopropia may not have had time to hyalinize. How",
"corrected_text": " will give you pseudomembranes. Ischemic injury can also give it to you. And the one thing to note is that, so this patient had C. difficile colitis by laboratory, but he was not responding to treatment and they just decided to take a biopsy. And you can see here that in the lamina propria is not hyalinized. Now, does that mean that ischemia is excluded? No, because if it's, you know, it depends on the clinical history. If it's recent ischemia that happened within, I don't know, 24, 48 hours, you know, the hyalinization may not have had time to hyalinize. How",
"med_umls_ids": "[[{'entity': 'Pseudomembranes', 'concept_id': 'C0240821', 'confidence': 1.0}, {'entity': 'Clostridioides', 'concept_id': 'C4406271', 'confidence': 1.0}, {'entity': 'colitis', 'concept_id': 'C0009319', 'confidence': 1.0}, {'entity': 'ischemic injury', 'concept_id': 'C2945681', 'confidence': 0.8915668725967407}], [{'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'hyalinization', 'concept_id': 'C0333438', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}, {'entity': 'hyalinization', 'concept_id': 'C0333438', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_748",
"caption_rating": "8"
},
{
"": "1006174",
"caption": "Presence of high-volume, high-grade invasive cancer associated with extra-prostatic extension, positive margins, and lymph node metastasis.",
"image_path": "iklRyY1nBIE_image_7da9a82d-4e58-4ad6-99ed-e452daa7ec40.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['Presence of high-volume prostate cancer with poorly formed glands and single cells.', 'Intraductal component.']",
"noisy_text": " are associated with extra-postatic extension. They are associated with, which you can see here, they are associated with positive margins. They are associated with lymph node metastasis. It is not the introductal carcinoma of the prostate itself that is associated with those. It's the fact that you have high-volume, high-grade invasive cancer next door. It is the invasive cancer that does all those bad things. The introductal carcinoma itself is introductal. It's just invasive cancer colonizing a duct. So the introductal carcinoma itself doesn't do all those bad things. It is associated with high-grade invasive cancer that does the high tumor volume, extra-postatic extension, positive surgical margins, and lymph node metastasis. And I'll show you a case of that shortly. So if you look at this case, again, high-volume prostate cancer. You can see that a lot of the glands are poorly formed. There are some single cells in there. And once again, you see the introductal component here. You can",
"corrected_text": " are associated with extra-prostatic extension. They are associated with, which you can see here, they are associated with positive margins. They are associated with lymph node metastasis. It is not the intrAductal carcinoma of the prostate itself that is associated with those. It's the fact that you have high-volume, high-grade invasive cancer next door. It is the invasive cancer that does all those bad things. The intrAductal carcinoma itself is intracystic. It's just invasive cancer colonizing a duct. So the intrAductal carcinoma itself doesn't do all those bad things. It is associated with high-grade invasive cancer that does the high tumor volume, extra-prostatic extension, positive surgical margins, and lymph node metastasis. And I'll show you a case of that shortly. So if you look at this case, again, high-volume prostate cancer. You can see that a lot of the glands are poorly formed. There are some single cells in there. And once again, you see the intracystic component here. You can",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'high-volume', 'concept_id': 'C3494218', 'confidence': 0.8583465814590454}, {'entity': 'high-grade invasive cancer', 'concept_id': 'C1512433', 'confidence': 0.6872689723968506}, {'entity': 'associated with', 'concept_id': 'C0332281', 'confidence': 1.0}, {'entity': 'extra-prostatic extension', 'concept_id': 'C1717821', 'confidence': 0.8074824213981628}, {'entity': 'positive margins', 'concept_id': 'C1709603', 'confidence': 1.0}, {'entity': 'lymph node metastasis', 'concept_id': 'C0686619', 'confidence': 1.0}], [{'entity': 'Intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'associated with', 'concept_id': 'C0332281', 'confidence': 1.0}, {'entity': 'factors', 'concept_id': 'C1257900', 'confidence': 0.8623767495155334}, {'entity': 'invasive cancer', 'concept_id': 'C0677898', 'confidence': 1.0}], [{'entity': 'Intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}, {'entity': 'colonizing', 'concept_id': 'C1300196', 'confidence': 0.61208176612854}, {'entity': 'duct', 'concept_id': 'C0687028', 'confidence': 1.0}, {'entity': 'associated with', 'concept_id': 'C0332281', 'confidence': 1.0}, {'entity': 'high-grade invasive cancer', 'concept_id': 'C1512433', 'confidence': 0.6872689723968506}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'outcomes', 'concept_id': 'C1274040', 'confidence': 0.8844040036201477}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_749",
"caption_rating": "10"
},
{
"": "1007788",
"caption": "The biopsy is of the stomach and is being examined for H. pylori, which secretes chemotactic factors for neutrophils.",
"image_path": "r7OA0Trj5hQ_image_f8985c1c-5f51-4587-98a1-56cb0db65fb7.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['neutrophils', 'neutrophils']",
"noisy_text": " But I just want to know whether you are able to understand or not. This is a gastric biopsy where you have to look for H. pylori because the H. pylori secrete some chemotactic factors for neutrophils. That's why the neutrophils come. And this is a crypt abscess. This is advanced active inflammation, neutrophils sitting in the glandular space. So this is cryptitis and this is crypt abscess. Here also you can see cryptitis. And this is again H. pylori in high power. Previously I showed you the H&E, and this is a ginseng stain. But please",
"corrected_text": " But I just want to know whether you are able to understand or not. This is a gastric biopsy where you have to look for H. pylori because the H. pylori secrete some chemotactic factors for neutrophils. That's why the neutrophils come. And this is a crypt abscess. This is advanced active inflammation, neutrophils sitting in the glandular space. So this is cryptitis and this is crypt abscess. Here also you can see cryptitis. And this is again H. pylori in high power. Previously I showed you the H&E, and this is a ginseng stain. But please",
"med_umls_ids": "[[{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'H. pylori', 'concept_id': 'C0079488', 'confidence': 1.0}, {'entity': 'secretes', 'concept_id': 'C1327616', 'confidence': 0.8702053427696228}, {'entity': 'chemotactic factors', 'concept_id': 'C0008013', 'confidence': 1.0}, {'entity': 'neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}], [{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'glandular spaces', 'concept_id': 'C0225353', 'confidence': 0.788912296295166}, {'entity': 'inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}, {'entity': 'crypt', 'concept_id': 'C1880192', 'confidence': 1.0}, {'entity': 'abscess', 'concept_id': 'C0000833', 'confidence': 1.0}], [{'entity': 'Cryptitis', 'concept_id': 'C1394254', 'confidence': 0.9999998807907104}, {'entity': 'crypt', 'concept_id': 'C1880192', 'confidence': 1.0}, {'entity': 'abscess', 'concept_id': 'C0000833', 'confidence': 1.0}, {'entity': 'visible', 'concept_id': 'C0205379', 'confidence': 0.9999998807907104}, {'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}], [{'entity': 'H. pylori', 'concept_id': 'C0079488', 'confidence': 1.0}, {'entity': 'visible', 'concept_id': 'C0205379', 'confidence': 0.9999998807907104}, {'entity': 'power', 'concept_id': 'C0032863', 'confidence': 1.0}, {'entity': 'ginseng stain', 'concept_id': 'C0086767', 'confidence': 0.8339173197746277}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_750",
"caption_rating": "8"
},
{
"": "1004809",
"caption": "Presence of pigmented histiocytes.",
"image_path": "8S4LeiO6Bbk_image_da91943b-95f1-427f-85ac-c15b9d31eae8.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['collagen balls', 'spindle-shaped cells', 'lipophagic cells', 'ringed siderophages', 'pigmented histiocytes', 'collagen balls', 'spindle-shaped cells', 'lipophagic cells', 'ringed siderophages', 'pigmented histiocytes']",
"noisy_text": " these collagen balls that are being surrounded by cells that have a somewhat spindled shape. The nuclei are spindled over our fusiform and they're kind of wrapping around these collagen bundles. In this same area, we can begin to see some lipophagia. So we see these large histiocytes containing lipid. Some of them are multi-nucleated and some of these are actually ringed siderophages. So we see large multi-nucleated histiocytes with a ring of nuclei and they contain not only lipid vacuoles but hemocentaurant. And these are particularly common in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes",
"corrected_text": " these collagen balls that are being surrounded by cells that have a somewhat spindle-shaped. The nuclei are spindle-shaped over our fusiform and they're kind of wrapping around these collagen bundles. In this same area, we can begin to see some lipophagic. So we see these large histiocytes containing lipid. Some of them are multi-nucleated and some of these are actually ringed siderophages. So we see large multinucleated histiocytes with a ring of nuclei and they contain not only lipid vacuoles but hemosiderin. And these are particularly common in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'collagen balls', 'concept_id': 'C0009325', 'confidence': 0.7217866778373718}, {'entity': 'surrounded', 'concept_id': 'C1282914', 'confidence': 1.0}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}], [{'entity': 'Lipophagic cells', 'concept_id': 'C0007584', 'confidence': 0.5962335467338562}, {'entity': 'lipid vacuoles', 'concept_id': 'C1179126', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'ringed', 'concept_id': 'C0325501', 'confidence': 0.77345871925354}, {'entity': 'siderophages', 'concept_id': 'C1136253', 'confidence': 0.7251443266868591}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_751",
"caption_rating": "8"
},
{
"": "1004546",
"caption": "Prominent nuclei and cribriform and micropapillary patterns are also indicative of dysplasia.",
"image_path": "r7OA0Trj5hQ_image_8a2d6c55-bd35-4e4e-a119-ebc49c3d2dec.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Cribriform and micropapillary patterns', 'Cribriform and micropapillary patterns']",
"noisy_text": " And the criteria are loss of polarity, nuclei reaching the surface. Here you can see nuclei reaching the surface. Prominent nuclei, if you see carefully for 10 seconds, you can start seeing the nuclei and cribriformic and micropapillary. This concept of dysplasia, low-grade dysplasia and high-grade dysplasia is very, very essential because you can apply this criteria in any organ. You can apply it in the pancreas. You can apply it in the gallbladder. You can apply it in the bile duct. Even you can apply it in the breast. You can apply it in the prostate. You can apply it",
"corrected_text": " And the criteria are loss of polarity, nuclei reaching the surface. Here you can see nuclei reaching the surface. Prominent nuclei, if you see carefully for 10 seconds, you can start seeing the nuclei and cribriform and micropapillary. This concept of dysplasia, low-grade dysplasia and high-grade dysplasia is very, very essential because you can apply this criteria in any organ. You can apply it in the pancreas. You can apply it in the gallbladder. You can apply it in the bile duct. Even you can apply it in the breast. You can apply it in the prostate. You can apply it",
"med_umls_ids": "[[{'entity': 'criteria', 'concept_id': 'C0243161', 'confidence': 0.9999998807907104}, {'entity': 'dysplasia', 'concept_id': 'C0334044', 'confidence': 1.0}, {'entity': 'loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'cellular polarity', 'concept_id': 'C0085304', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}], [{'entity': 'Prominent', 'concept_id': 'C0205402', 'confidence': 0.9999999403953552}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'cribriform', 'concept_id': 'C1621425', 'confidence': 0.9999999403953552}, {'entity': 'micropapillary', 'concept_id': 'C1290608', 'confidence': 0.891559898853302}, {'entity': 'patterns', 'concept_id': 'C0449774', 'confidence': 1.0}, {'entity': 'indicative', 'concept_id': 'C2985705', 'confidence': 0.7675144076347351}, {'entity': 'dysplasia', 'concept_id': 'C0334044', 'confidence': 1.0}], [{'entity': 'concept', 'concept_id': 'C0178566', 'confidence': 1.0}, {'entity': 'dysplasia', 'concept_id': 'C0334044', 'confidence': 1.0}, {'entity': 'essential', 'concept_id': 'C0205224', 'confidence': 0.9999999403953552}, {'entity': 'organs', 'concept_id': 'C0178784', 'confidence': 1.0}, {'entity': 'pancreas', 'concept_id': 'C0030274', 'confidence': 0.9999999403953552}, {'entity': 'gallbladder', 'concept_id': 'C0016976', 'confidence': 0.9999999403953552}, {'entity': 'bile duct', 'concept_id': 'C0005400', 'confidence': 1.0}, {'entity': 'breast', 'concept_id': 'C0006141', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_752",
"caption_rating": "8"
},
{
"": "1008763",
"caption": "Identification of vein and artery based on elastic tissue strain.",
"image_path": "r7OA0Trj5hQ_image_febb4bba-96f0-4103-8059-ff8932c75cdf.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Severe dysplasia', 'Thick and thin blood vessels', 'Thick vessel wall', 'Narrowing of lumen', 'Vein and artery identification', 'No internal elastic lamina']",
"noisy_text": " And in the resection, you see like a heavy malformation, isn't it? Thick and thin blood vessels of varying sizes are seen. In high power, you can see very thick vessel wall with the narrowing of the lumen, whereas here, it is relatively preserved. So you want to know whether it is a vein or artery. Please believe me, this is a vein, and this is an artery. And that is proved by the elastic tissue strain. These are all pictures from Dr. Gonzalez's Twitter. And you can see here, there is no internal elastic lamina, whereas here,",
"corrected_text": " And in the resection, you see like a heavy malformation, isn't it? Thick and thin blood vessels of varying sizes are seen. In high power, you can see very thick vessel wall with the narrowing of the lumen, whereas here, it is relatively preserved. So you want to know whether it is a vein or artery. Please believe me, this is a vein, and this is an artery. And that is proved by the elastic tissue strain. These are all pictures from Dr. Gonzalez's Twitter. And you can see here, there is no internal elastic lamina, whereas here,",
"med_umls_ids": "[[{'entity': 'Severe', 'concept_id': 'C0205082', 'confidence': 1.0}, {'entity': 'resection', 'concept_id': 'C0015252', 'confidence': 1.0}], [{'entity': 'Thick', 'concept_id': 'C1280412', 'confidence': 1.0}, {'entity': 'thin', 'concept_id': 'C0205168', 'confidence': 1.0}, {'entity': 'sizes', 'concept_id': 'C0456389', 'confidence': 1.0}], [{'entity': 'Thick vessel wall', 'concept_id': 'C1180033', 'confidence': 0.6420797109603882}, {'entity': 'narrowing', 'concept_id': 'C0332463', 'confidence': 1.0}, {'entity': 'lumen', 'concept_id': 'C0524461', 'confidence': 0.9999998807907104}, {'entity': 'power', 'concept_id': 'C0032863', 'confidence': 1.0}], [{'entity': 'Identification', 'concept_id': 'C0020792', 'confidence': 1.0}, {'entity': 'vein', 'concept_id': 'C0042449', 'confidence': 1.0}, {'entity': 'artery', 'concept_id': 'C0003842', 'confidence': 1.0}, {'entity': 'elastic tissue', 'concept_id': 'C0013762', 'confidence': 1.0}, {'entity': 'strain', 'concept_id': 'C0080194', 'confidence': 1.0}], [{'entity': 'image', 'concept_id': 'C1696103', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_753",
"caption_rating": "7"
},
{
"": "1006829",
"caption": "The diagnosis is likely low-grade fibromyxoid sarcoma.",
"image_path": "QDb68_G1HR4_image_3594f719-d6fd-4c1d-bc83-4aa9c52ac1e9.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Sarcoma cells', 'Fibrous area with delicate collagen.']",
"noisy_text": " So I'm going to go in even higher power to convince you, yes these are sarcoma cells right here. They just don't look very atypical at all. They look bland, they don't usually have pleomorphism, they look uniform, they look very much like each other and look very fibroblastic and again this is, I've talked in other videos this is a true statement about many of the translocation associated sarcomas. They have the same molecular abnormality in every single cell so all the cells look alike. They look monotonous and uniform rather than pleomorphic, okay? So there's a few exceptions to this we'll talk about in a minute but this is the cytologic feature of low grade fibromyxoid sarcoma so that's the fibrous area, delicate collagen kind of",
"corrected_text": " So I'm going to go in even higher power to convince you, yes these are sarcoma cells right here. They just don't look very atypical at all. They look bland, they don't usually have pleomorphism, they look uniform, they look very much like each other and look very fibroblastic and again this is, I've talked in other videos this is a true statement about many of the translocation associated sarcomas. They have the same molecular abnormality in every single cell so all the cells look alike. They look monotonous and uniform rather than pleomorphic, okay? So there's a few exceptions to this we'talk about in a minute but this is the cytologic feature of low grade fibromyxoid sarcoma so that's the fibrous area, delicate collagen kind of",
"med_umls_ids": "[[{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'sarcoma cells', 'concept_id': 'C0024302', 'confidence': 0.7867116332054138}, {'entity': 'uniform', 'concept_id': 'C0205375', 'confidence': 1.0}, {'entity': 'fibroblastic', 'concept_id': 'C0016030', 'confidence': 0.8876925110816956}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}], [{'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_754",
"caption_rating": "8"
},
{
"": "1006198",
"caption": "Mycosuria is present in a 69-year-old male patient with hematuria and elevated PSA levels.",
"image_path": "iklRyY1nBIE_image_d7c2bb0e-8d25-4b93-96f4-a06df852db5d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " This is just basal cell hyperplasia. Sometimes you can have urothelial metaplasia also occurring simultaneously. All right, so the next case is case 7. Case 7 is a 69-year-old gentleman with hematuria and mycosuria. So this is the first time we are hearing that word, mycosuria. So we've had elevated PSA levels. We've had positive DREs. We've had hematuria. But this is the first patient that has mycosuria. And that's of some significance, which you'll see shortly. So let's take a look at this case. Again, this doesn't look like anything I've shown",
"corrected_text": " This is just basal cell hyperplasia. Sometimes you can have urothelial metaplasia also occurring simultaneously. All right, so the next case is case 7. Case 7 is a 69-year-old gentleman with hematuria and mycosuria. So this is the first time we are hearing that word, mycosuria. So we've had elevated PSA levels. We've had positive DREs. We've had hematuria. But this is the first patient that has mycosuria. And that's of some significance, which you'll see shortly. So let's take a look at this case. Again, this doesn't look like anything I've shown",
"med_umls_ids": "[[{'entity': 'Basal cell', 'concept_id': 'C0596155', 'confidence': 1.0}], [{'entity': 'Urothelial metaplasia', 'concept_id': 'C0334028', 'confidence': 0.8153573870658875}, {'entity': 'simultaneously', 'concept_id': 'C0521115', 'confidence': 1.0}, {'entity': 'basal cell hyperplasia', 'concept_id': 'C0333990', 'confidence': 1.0}], [{'entity': 'Mycosuria', 'concept_id': 'C0017979', 'confidence': 0.7108948826789856}, {'entity': 'male', 'concept_id': 'C0086582', 'confidence': 1.0}, {'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'hematuria', 'concept_id': 'C0018965', 'confidence': 1.0}, {'entity': 'elevated', 'concept_id': 'C0205250', 'confidence': 0.9999999403953552}, {'entity': 'PSA', 'concept_id': 'C0138741', 'confidence': 1.0}, {'entity': 'levels', 'concept_id': 'C0441889', 'confidence': 1.0}], [{'entity': 'Mycosuria', 'concept_id': 'C0017979', 'confidence': 0.7108948826789856}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_755",
"caption_rating": "8"
},
{
"": "1007367",
"caption": "Evidence of maturation with depth and no mitotic pairs.",
"image_path": "8S4LeiO6Bbk_image_2596344b-b932-450f-aa3d-0ffba92fe1cd.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['dermis']",
"noisy_text": " because this was the initial shave. And you can see that we've got a dome-shaped papule here. And we've got a few nests of melanocytes along the DEJ. And these melanocytes are normal in appearance, a round oval nuclei and a moderate amount of cytoplasm. And then we have nest cords and strands of otherwise banal appearing or banal appearing melanocytes present within the underlying dermis. There is evidence of maturation with depth in these sections, and no mitotic pairs. In the central portion of the specimen, you can see that the dermis is a little more sclerotic. And we've got the presence of separately heavily pigmented melanovagias. And then if we",
"corrected_text": " because this was the initial shave. And you can see that we've got a dome-shaped papule here. And we've got a few nests of melanocytes along the DEJ. And these melanocytes are normal in appearance, a round oval nuclei and a moderate amount of cytoplasm. And then we have nest cords and strands of otherwise banal appearing or banal appearing melanocytes present within the underlying dermis. There is evidence of maturation with depth in these sections, and no mitotic pairs. In the central portion of the specimen, you can see that the dermis is a little more sclerotic. And we've got the presence of separately heavily pigmented melanovagias. And then if we",
"med_umls_ids": "[[{'entity': 'Dome-shaped papule', 'concept_id': 'C1711316', 'confidence': 0.752353847026825}, {'entity': 'nests', 'concept_id': 'C0035253', 'confidence': 0.7275967001914978}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'DEJ', 'concept_id': 'C0385794', 'confidence': 0.5962325930595398}], [{'entity': 'Nest cords', 'concept_id': 'C0884973', 'confidence': 0.7039703726768494}, {'entity': 'strands', 'concept_id': 'C0600383', 'confidence': 0.800572395324707}, {'entity': 'banal', 'concept_id': 'C0004722', 'confidence': 0.7279530763626099}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}], [{'entity': 'Evidence', 'concept_id': 'C3887511', 'confidence': 1.0}, {'entity': 'maturation', 'concept_id': 'C0678723', 'confidence': 1.0}, {'entity': 'depth', 'concept_id': 'C0205125', 'confidence': 1.0}, {'entity': 'mitotic', 'concept_id': 'C1513354', 'confidence': 1.0}, {'entity': 'pairs', 'concept_id': 'C0600436', 'confidence': 0.8094210028648376}], [{'entity': 'Sclerotic', 'concept_id': 'C0036429', 'confidence': 0.9999999403953552}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'melanophages', 'concept_id': 'C3280463', 'confidence': 0.9375340938568115}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_756",
"caption_rating": "8"
},
{
"": "1004948",
"caption": "Invasion of atypical columnar epithelial cells into the stroma is diagnostic of mucinous cystadenocarcinoma.",
"image_path": "3mRB9j0eyVM_image_5718b0ef-b209-4f1e-93b6-f24568babc77.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gynecologic', 'Hematopathology', 'Soft tissue']",
"roi_text": "['Mucin-filled ovaries with infiltration', 'Atypical columnar epithelial cells with invasion', 'Stroma']",
"noisy_text": " we call these tumors as borderline mucin. Now we come to the mucinous cyst adenocarcinoma these are the mucin filled ovaries and they even on the gross findings they show the presence of infiltration here. Atypia, marked atypia in the columnar type of epithelial cells and these atypical cells they show invasion. So when these atypical cells atypical columnar type of epithelial cells they show definite invasion in the stroma we say that this is mucinous cyst adenocarcinoma. Now another type of tumor that is called endometroid tumor. So endometroid tumor these are actually few cases",
"corrected_text": " we call these tumors as borderline mucin. Now we come to the mucinous cystadenocarcinoma these are the mucin filled ovaries and they even on the gross findings they show the presence of infiltration here. Atypia, marked atypia in the columnar type of epithelial cells and these atypical cells they show invasion. So when these atypical cells atypical columnar type of epithelial cells they show definite invasion in the stroma we say that this is mucinous cystadenocarcinoma. Now another type of tumor that is endometrioid tumor. So endometrioid tumor these are actually few cases",
"med_umls_ids": "[[{'entity': 'Borderline mucin', 'concept_id': 'C0205189', 'confidence': 0.8083650469779968}, {'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}], [{'entity': 'Mucinous cystadenocarcinoma', 'concept_id': 'C0206699', 'confidence': 1.0}, {'entity': 'infiltration', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'atypia', 'concept_id': 'C0741302', 'confidence': 0.9999999403953552}, {'entity': 'columnar epithelial cells', 'concept_id': 'C0225338', 'confidence': 1.0}], [{'entity': 'Invasion', 'concept_id': 'C1269955', 'confidence': 1.0}, {'entity': 'atypical', 'concept_id': 'C0205182', 'confidence': 1.0}, {'entity': 'columnar epithelial cells', 'concept_id': 'C0225338', 'confidence': 1.0}, {'entity': 'stroma', 'concept_id': 'C0927195', 'confidence': 1.0}, {'entity': 'diagnostic', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'mucinous cystadenocarcinoma', 'concept_id': 'C0206699', 'confidence': 1.0}], [{'entity': 'Endometrioid tumors', 'concept_id': 'C0474809', 'confidence': 0.902359127998352}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "2.0",
"height": "720.0",
"width": "960.0",
"id": "test_757",
"caption_rating": "9"
},
{
"": "1005402",
"caption": "Presence of extensive ulceration and hemorrhage.",
"image_path": "r7OA0Trj5hQ_image_08f3aa85-fe3d-4f39-b651-8b094e657890.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['hemorrhage', 'extensive ulceration', 'hemorrhage', 'gastric mucosa', 'willy-formed changes', 'chemical gastritis', 'antrum', 'pylorus', 'neutrophils']",
"noisy_text": " Extensive ulceration and hemorrhage. As far as the poisoning, any other chemicals, or any chemotherapy, clinical history is very, very important to make a exact diagnosis. This is the surface epithelial changes where the surface looks more willy-formed. This is a gastric, if it is small intestine, then it is fine, but this is a gastric mucosa. You see a lot of willy-formed changes. These willy-formed changes are very important in the diagnosis of chemical gastritis if the biopsy is taken from the antrum or pylorus. What happens there? The bile is trying to come into the stomach, so the stomach is trying to become small intestine. That's why you see willy-formed changes in the chemical gastritis. Here, what do you see in the surface epithelium? See, a lot of neutrophils are sitting. Remember, I told you, this is",
"corrected_text": " Extensive ulceration and hemorrhage. As far as the poisoning, any other chemicals, or any chemotherapy, clinical history is very, very important to make a exact diagnosis. This is the surface epithelial changes where the surface looks more willy-formed. This is a gastric, if it is small intestine, then it is fine, but this is a gastric mucosa. You see a lot of willy-formed changes. These willy-formed changes are very important in the diagnosis of chemical gastritis if the biopsy is taken from the antrum or pylorus. What happens there? The bile is trying to come into the stomach, so the stomach is trying to become small intestine. That's why you see willy-formed changes in the chemical gastritis. Here, what do you see in the surface epithelium? See, a lot of neutrophils are sitting. Remember, I told you, this is",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'extensive', 'concept_id': 'C0205231', 'confidence': 1.0}, {'entity': 'ulceration', 'concept_id': 'C0041582', 'confidence': 1.0}, {'entity': 'hemorrhage', 'concept_id': 'C0019080', 'confidence': 1.0}], [{'entity': 'Clinical history', 'concept_id': 'C5204342', 'confidence': 0.9999999403953552}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'poisoning', 'concept_id': 'C0032343', 'confidence': 1.0}, {'entity': 'exposure to', 'concept_id': 'C0332157', 'confidence': 0.9999998807907104}, {'entity': 'chemicals', 'concept_id': 'C0220806', 'confidence': 1.0}, {'entity': 'chemotherapy', 'concept_id': 'C0013216', 'confidence': 1.0}], [{'entity': 'Surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'epithelial changes', 'concept_id': 'C0221908', 'confidence': 0.7544435858726501}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'gastric mucosa', 'concept_id': 'C0017136', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}, {'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'antrum', 'concept_id': 'C0034193', 'confidence': 1.0}, {'entity': 'pylorus', 'concept_id': 'C0034196', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'surface epithelium', 'concept_id': 'C1182809', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_758",
"caption_rating": "8"
},
{
"": "1005195",
"caption": "Caution against taking superficial shave biopsies of DFSPs and recommendation for deep incisional biopsy when dealing with a soft tissue neoplasm.",
"image_path": "LlPaENuqzVQ_image_cc6b78f5-e9e0-4a20-bb93-d4a40aa06b50.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['Storiform pattern', 'Ring chromosome', 'Collagen A', 'Platelet-derived growth factor', 'Soft tissue neoplasm', 'Storiform pattern', 'Ring chromosome', 'Collagen A', 'Platelet-derived growth factor', 'Soft tissue neoplasm']",
"noisy_text": " you do have the nice, beautiful storiform pattern here. And you don't really need a CD34 stain here. You can do it if you want to, if you like to sort of charge patients extra money, but this is a classic DFSB. And that ring chromosome, the collagen A, platelet-derived growth factor, the translocation is classic for that. And one other thing, if you biopsy the surface of DFSB, sometimes it can look like a neurofibroma. So beware of taking superficial shave biopsies of DFSBs. You need to take a deep incisional biopsy. Whenever you're dealing with a soft tissue neoplasm and dermatology, get out the knife and fork. Don't get the punch biopsy out. Don't ever do a shave on it. So you got to take a real biopsy when you're dealing with a soft tissue neoplasm because of",
"corrected_text": " you do have the nice, beautiful storiform pattern here. And you don't really need a CD34 stain here. You can do it if you want to, if you like to sort of charge patients extra money, but this is a classic DFSP. And that ring chromosome, the collagen A, platelet-derived growth factor, the translocation is classic for that. And one other thing, if you biopsy the surface of DFSP, sometimes it can look like a neurofibroma. So beware of taking superficial shave biopsies of DFSBs. You need to take a deep incisional biopsy. Whenever you're dealing with a soft tissue neoplasm and dermatology, get out the knife and fork. Don't get the punch biopsy out. Don't ever do a shave on it. So you got to take a real biopsy when you're dealing with a soft tissue neoplasm because of",
"med_umls_ids": "[[{'entity': 'Identification', 'concept_id': 'C0020792', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}, {'entity': 'storiform pattern', 'concept_id': 'C1336510', 'confidence': 0.8142904043197632}, {'entity': 'ring chromosome', 'concept_id': 'C0035639', 'confidence': 1.0}, {'entity': 'collagen A', 'concept_id': 'C0009325', 'confidence': 0.9128584265708923}, {'entity': 'platelet-derived growth factor', 'concept_id': 'C0032200', 'confidence': 1.0}, {'entity': 'translocation', 'concept_id': 'C0040715', 'confidence': 1.0}], [{'entity': 'Caution', 'concept_id': 'C1882442', 'confidence': 0.7039048671722412}, {'entity': 'superficial', 'concept_id': 'C0205124', 'confidence': 1.0}, {'entity': 'DFSPs', 'concept_id': 'C0334464', 'confidence': 0.8083938360214233}, {'entity': 'recommendation', 'concept_id': 'C0034866', 'confidence': 1.0}, {'entity': 'deep incisional biopsy', 'concept_id': 'C0184922', 'confidence': 0.8345454335212708}, {'entity': 'dealing', 'concept_id': 'C0556449', 'confidence': 0.7019717693328857}, {'entity': 'soft tissue neoplasm', 'concept_id': 'C0037579', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_759",
"caption_rating": "9"
},
{
"": "1006380",
"caption": "Presence of sarcoid-like granulomas in the lung of the patient who was taking TNF for ankylosing spondylitis.",
"image_path": "sDFjOtMAYrk_image_a784bb16-bb1b-42cd-8ace-85ebce853b45.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['Sarcoid-like granulomas in the lung.', 'Sarcoid-like granulomas in the lung.']",
"noisy_text": " patients who develop sarcoid-like granulomas, at least in the lung. So maybe the process just takes a little while to resolve after the patient's taken off the drug. Yeah, so the patient, we did all the stains, albeit they're low yield. The patient had no risk factors for TB. They never tested him for TB, though. But they thought clinically, that's not an issue. He got tested for a couple of other things. His ACE was within normal limits, and yeah, nothing. He just removed the drug and said, okay, let's see if this works. And that turned out to be the patient had, he was taking TNF for ankylosing spondylitis. Ankylosing spondylitis, yeah. Coming back to our",
"corrected_text": " patients who develop sarcoid-like granulomas, at least in the lung. So maybe the process just takes a little while to resolve after the patient's taken off the drug. Yeah, so the patient, we did all the stains, albeit they're low yield. The patient had no risk factors for TB. They never tested him for TB, though. But they thought clinically, that's not an issue. He got tested for a couple of other things. His ACE was within normal limits, and yeah, nothing. He just removed the drug and said, okay, let's see if this works. And that turned out to be the patient had, he was taking TNF for ankylosing spondylitis. Ankylosing spondylitis, yeah. Coming back to our",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'sarcoid-like granulomas', 'concept_id': 'C0333419', 'confidence': 0.7742165923118591}, {'entity': 'lung', 'concept_id': 'C0024109', 'confidence': 1.0}, {'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'TNF', 'concept_id': 'C0812246', 'confidence': 1.0}, {'entity': 'ankylosing spondylitis', 'concept_id': 'C0038013', 'confidence': 1.0}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'risk factors', 'concept_id': 'C0035648', 'confidence': 1.0}, {'entity': 'TB', 'concept_id': 'C0041296', 'confidence': 1.0}, {'entity': 'ACE', 'concept_id': 'C0050385', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_760",
"caption_rating": "9"
},
{
"": "1009270",
"caption": "Perineuriomas and low-grade fibromyxoid sarcomas can have whirled or swirled areas.",
"image_path": "QDb68_G1HR4_image_e32c5434-c6dd-42c1-9c99-053fb810a06d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " that's why this tumor one of the mimics that you can see one of the histologic mimics is perineurioma and I have another video about perineurioma that really goes into detail. Perineuriomas often have cells that look very much like this and both perineurioma as well as low-grade fibromyxoid sarcoma can have very whirled or swirled areas. This one's not really showing that but some of them do, they have a lot of whirling pattern. So the two other things that keep in the differential here are perineurioma and also dermatofibrosarcoma protuberans, DFSP,",
"corrected_text": " that's why this tumor one of the mimics that you can see one of the histologic mimics is perineurioma and I have another video about perineurioma that really goes into detail. Perineuriomas often have cells that look very much like this and both perineurioma as well as low-grade fibromyxoid sarcoma can have very whirled or swirled areas. This one's not really showing that but some of them do, they have a lot of whirling pattern. So the two other things that keep in the differential here are perineurioma and also dermatofibrosarcoma protuberans, DFSP,",
"med_umls_ids": "[[{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'histologic', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'perineurioma', 'concept_id': 'C0751691', 'confidence': 0.9999999403953552}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}], [{'entity': 'Perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcomas', 'concept_id': 'C1275282', 'confidence': 0.8123146891593933}, {'entity': 'whirled', 'concept_id': 'C1424217', 'confidence': 0.6834293007850647}, {'entity': 'swirled areas', 'concept_id': 'C1968905', 'confidence': 0.5657616853713989}], [{'entity': 'Dermatofibrosarcoma', 'concept_id': 'C0206647', 'confidence': 1.0}, {'entity': 'differential diagnosis', 'concept_id': 'C0011906', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_761",
"caption_rating": "8"
},
{
"": "1006751",
"caption": "Elastic cartilage is found in the external ear and the epiglottis.",
"image_path": "ib991vTA67A_image_eecf8160-ce87-46b5-85bd-44bdf9b62159.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Head and Neck']",
"roi_text": "['epiglottis', 'elastic cartilage', 'lacunas', 'chondrocytes', 'external ear', 'epiglottis', 'reticular connective tissue', 'epithelial tissue']",
"noisy_text": " the answer, this is elastic cartilage, you know it's a cartilage because you see the lacunas, so this is lacuna right here with the chondrocyte in it, where do you find elastic cartilage, think of the E's, elastic cartilage, external ear and the epiglottis, so elastic cartilage, external ear, epiglottis, that's where you're going to find elastic cartilage, that was number nineteen, number twenty, where do you, see this is a reticular connective tissue again, where do you find it, underneath all epithelial tissue, underneath all epithelial tissue, remember",
"corrected_text": " the answer, this is elastic cartilage, you know it's a cartilage because you see the lacunas, so this is lacuna right here with the chondrocyte in it, where do you find elastic cartilage, think of the E's, elastic cartilage, external ear and the epiglottis, so elastic cartilage, external ear, epiglottis, that's where you're going to find elastic cartilage, that was number nineteen, number twenty, where do you, see this is a reticular connective tissue again, where do you find it, underneath all epithelial tissue, underneath all epithelial tissue, remember",
"med_umls_ids": "[[{'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'examined', 'concept_id': 'C0332128', 'confidence': 1.0}, {'entity': 'elastic cartilage', 'concept_id': 'C0682559', 'confidence': 0.9999998807907104}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lacunas', 'concept_id': 'C1459585', 'confidence': 0.8563621044158936}, {'entity': 'chondrocytes', 'concept_id': 'C0225369', 'confidence': 1.0}], [{'entity': 'Elastic cartilage', 'concept_id': 'C0682559', 'confidence': 0.9999998807907104}, {'entity': 'external ear', 'concept_id': 'C0013453', 'confidence': 1.0}, {'entity': 'epiglottis', 'concept_id': 'C0014540', 'confidence': 0.9999999403953552}], [{'entity': 'Reticular', 'concept_id': 'C0439739', 'confidence': 1.0}, {'entity': 'connective tissue', 'concept_id': 'C0009780', 'confidence': 1.0}, {'entity': 'epithelial tissue', 'concept_id': 'C0014609', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1152.0",
"id": "test_762",
"caption_rating": "8"
},
{
"": "1004671",
"caption": "Eosinophilic gastritis is diagnosed when there are more than five eosinophils per high power field in the stomach.",
"image_path": "r7OA0Trj5hQ_image_c6eb73a1-9f9f-4e7a-911d-5342b8bef44b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['lamina propria edema', 'muscularis mucosa', 'neutrophils', 'eosinophils', 'stomach', 'esophagus', 'enteritis', 'colitis', 'lamina propria edema', 'muscularis mucosa', 'neutrophils', 'eosinophils', 'stomach', 'esophagus', 'enteritis', 'colitis']",
"noisy_text": " Lamina propria edema and muscularis mucosa coming into the lamina propria. These are the three criterias. When you see it in the anterobiopsy, think of chemical gastritis that can be seen in biliary reflux or NSAID use. Lot of inflammation results. Remember I told you if you see more than five neutrophils, more than five eosinophils sitting in the lamina propria or more than 15 eosinophils per high power field, that is a eosinophilic gastritis, if it is from the stomach. If it is esophagus, it is eosinophilic esophagitis, eosinophilic entritis, eosinophilic colitis. So eosinophilic",
"corrected_text": " Lamina propria edema and muscularis mucosa coming into the lamina propria. These are the three criterias. When you see it in the antral biopsy, think of chemical gastritis that can be seen in biliary reflux or NSAID use. Lot of inflammation results. Remember I told you if you see more than five neutrophils, more than five eosinophils sitting in the lamina propria or more than 15 or more eosinophils per high power field, that is a eosinophilic gastritis, if it is from the stomach. If it is esophagus, it is eosinophilic esophagitis, eosinophilic enteritis, eosinophilic colitis. So eosinophilic",
"med_umls_ids": "[[{'entity': 'Lamina propria edema', 'concept_id': 'C1179187', 'confidence': 0.7593827247619629}, {'entity': 'muscularis mucosa', 'concept_id': 'C0225357', 'confidence': 0.9999998807907104}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'criteria', 'concept_id': 'C0243161', 'confidence': 0.9999998807907104}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}], [{'entity': 'Inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}], [{'entity': 'Eosinophilic gastritis', 'concept_id': 'C0267154', 'confidence': 1.0}, {'entity': 'diagnosed', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}], [{'entity': 'Eosinophilic esophagitis', 'concept_id': 'C0341106', 'confidence': 0.9999999403953552}, {'entity': 'eosinophilic enteritis', 'concept_id': 'C1262481', 'confidence': 1.0}, {'entity': 'eosinophilic colitis', 'concept_id': 'C0267448', 'confidence': 1.0}, {'entity': 'diagnoses', 'concept_id': 'C0011900', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_763",
"caption_rating": "8"
},
{
"": "1007056",
"caption": "MAC is a neoplasm that is diffuse in nature and does not show a lot of mitoses or individual cellular atypia.",
"image_path": "LlPaENuqzVQ_image_81c1c618-4711-4364-91a3-add587d50694.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['MAC looks like a syringoma.', 'MAC looks like a syringoma.']",
"noisy_text": " And basically, another name for MAC that I actually like better is syringomatous carcinoma because it looks like a syringoma. And if you look at the individual cells, usually you don't see a lot of mitoses. There's not a lot of individual cellular atypia, not a lot of pleomorphism. It's really a neoplasm that causes problems because of its diffuse nature. Some cancers are aggressive because they metastasize. Some are more aggressive because they just like crab. They just gradually erode everything and they just destroy everything in their path. And so this is more that sort of thing and it goes deep. And one other thing that you look for when you're",
"corrected_text": " And basically, another name for MAC that I actually like better is syringomatous carcinoma because it looks like a syringoma. And if you look at the individual cells, usually you don't see a lot of mitoses. There's not a lot of individual cellular atypia, not a lot of pleomorphism. It's really a neoplasm that causes problems because of its diffuse nature. Some cancers are aggressive because they metastasize. Some are more aggressive because they just like crab. They just gradually erode everything and they just destroy everything in their path. And so this is more that sort of thing and it goes deep. And one other thing that you look for when you're",
"med_umls_ids": "[[{'entity': 'MAC', 'concept_id': 'C0009545', 'confidence': 0.9999999403953552}, {'entity': 'Mycobacterium avium complex', 'concept_id': 'C0026914', 'confidence': 1.0}, {'entity': 'syringomatous carcinoma', 'concept_id': 'C0346027', 'confidence': 1.0}, {'entity': 'syringoma', 'concept_id': 'C0206673', 'confidence': 1.0}], [{'entity': 'MAC', 'concept_id': 'C0009545', 'confidence': 0.9999999403953552}, {'entity': 'neoplasm', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'diffuse', 'concept_id': 'C0205219', 'confidence': 1.0}, {'entity': 'nature', 'concept_id': 'C0349590', 'confidence': 1.0}, {'entity': 'mitoses', 'concept_id': 'C0026255', 'confidence': 1.0}, {'entity': 'cellular atypia', 'concept_id': 'C0333865', 'confidence': 0.9999999403953552}], [{'entity': 'MAC', 'concept_id': 'C0009545', 'confidence': 0.9999999403953552}, {'entity': 'deep cancer', 'concept_id': 'C0006826', 'confidence': 0.6357579231262207}, {'entity': 'destroys', 'concept_id': 'C0681205', 'confidence': 0.6218703985214233}, {'entity': 'path', 'concept_id': 'C1705483', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_764",
"caption_rating": "9"
},
{
"": "1008905",
"caption": "Description of combined nevi, which are melanocytic tumors characterized by a benign nevus and a population of epithelial-like melanocytes.",
"image_path": "8S4LeiO6Bbk_image_9dea1855-71fe-4f95-b8b0-528a25101f8a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['population of banal appearing melanocytes', 'balloon melanocytes', 'benign nevus', 'cellular blue nevus']",
"noisy_text": " Those are combined nevi because you usually have a population of banal appearing melanocytes and balloon melanocytes. At that point, inactivated melanocytic tumors are frequently combined nevi, commonly characterized by banal nevus and a population of very epithelial spits like melanocytes. So anyway, all possible combinations are... And in actuality, a deep penetrating nevus is frequently combined nevus with a combination of banal nevus and what looks oftentimes like a cellular blue nevus. So anyway, this is a combined melanocytic nevus. So that's all I have for you. And if you have any questions, again, please feel free to reach out. You can email me at tdavis.sagesdx.com or education at sagesdx.com. Thank you very much. We're always looking for suggestions. So if you have any topics that you would like to have covered, please feel free to shoot me an email. Thanks so much for your attention. Have a good evening.",
"corrected_text": " Those are combined nevi because you usually have a population of banal appearing melanocytes and balloon melanocytes. At that point, inactivated melanocytic tumors are frequently combined nevi, commonly characterized by benign nevus and a population of very epithelial spits like melanocytes. So anyway, all possible combinations are... And in actuality, a deep penetrating nevus is frequently combined nevus with a combination of benign nevus and what looks oftentimes like a cellular blue nevus. So anyway, this is a combined melanocytic nevus. So that's all I have for you. And if you have any questions, again, please feel free to reach out. You can email me at tdavis.sagesdx.com or education at sagesdx.com. Thank you very much. We're always looking for suggestions. So if you have any topics that you would like to have covered, please feel free to shoot me an email. Thanks so much for your attention. Have a good evening.",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'combined', 'concept_id': 'C0205195', 'confidence': 1.0}, {'entity': 'nevi', 'concept_id': 'C0027960', 'confidence': 1.0}, {'entity': 'melanocytic tumors', 'concept_id': 'C0349501', 'confidence': 0.7923030257225037}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'benign nevus', 'concept_id': 'C1456781', 'confidence': 1.0}, {'entity': 'population', 'concept_id': 'C0032659', 'confidence': 1.0}, {'entity': 'epithelial-like', 'concept_id': 'C0334254', 'confidence': 0.6890533566474915}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_765",
"caption_rating": "8"
},
{
"": "1007608",
"caption": "CD68 is strongly positive in xanthoma.",
"image_path": "r7OA0Trj5hQ_image_c7ed1339-6895-420a-bdd8-11bd0d9bacdb.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['centrally placed nucleus', 'young males', 'inflammatory bowel disease', 'lamina propria', 'distinct cell border', 'foamy cytoplasm', 'centrally placed nucleus', 'gastric xanthoma']",
"noisy_text": " It is commonly seen in young males, and they present with the signs and symptoms of inflammatory bowel disease. Interesting condition. Here, the lamina propria is full of cells with a distinct cell border, abundant foamy cytoplasm, most of the time centrally placed nucleus. Sometimes it is pushed to the periphery. The central nuclear placement is very important for a diagnosis of xanthoma. For a signet cells, it will be predominantly peripherally pushed nucleus. And when you have doubt, you do a CD68, which will be strongly positive. And so this is a gastric xanthoma. Here, it",
"corrected_text": " It is commonly seen in young males, and they present with the signs and symptoms of inflammatory bowel disease. Interesting condition. Here, the lamina propria is full of cells with a distinct cell border, abundant foamy cytoplasm, most of the time centrally placed nucleus. Sometimes it is pushed to the periphery. The central nuclear placement is very important for a diagnosis of xanthoma. For a signet ring cells, it will be predominantly peripherally pushed nucleus. And when you have doubt, you do a CD68, which will be strongly positive. And so this is a gastric xanthoma. Here, it",
"med_umls_ids": "[[{'entity': 'Xanthoma', 'concept_id': 'C0302314', 'confidence': 1.0}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'young', 'concept_id': 'C0332239', 'confidence': 1.0}, {'entity': 'males', 'concept_id': 'C0086582', 'confidence': 1.0}, {'entity': 'signs', 'concept_id': 'C0220912', 'confidence': 0.9999999403953552}, {'entity': 'symptoms', 'concept_id': 'C0683368', 'confidence': 1.0}, {'entity': 'inflammatory bowel disease', 'concept_id': 'C0021390', 'confidence': 1.0}], [{'entity': 'Lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'cell border', 'concept_id': 'C0205284', 'confidence': 0.773768424987793}, {'entity': 'foamy cytoplasm', 'concept_id': 'C0010834', 'confidence': 0.7207725048065186}, {'entity': 'centrally', 'concept_id': 'C0205099', 'confidence': 0.7070305943489075}, {'entity': 'nucleus', 'concept_id': 'C0007610', 'confidence': 1.0}, {'entity': 'gastric xanthoma', 'concept_id': 'C1282522', 'confidence': 1.0}], [{'entity': 'CD68', 'concept_id': 'C0108799', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'xanthoma', 'concept_id': 'C0302314', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_766",
"caption_rating": "8"
},
{
"": "1006527",
"caption": "Discussion of a possible diagnosis of IBD based on the presence of pannate cell metaplasia and distortion associated with a lymphoid aggregate in the preserved lamina propria.",
"image_path": "sDFjOtMAYrk_image_c42be0a1-220f-4bfd-9737-e3ae913774fa.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['distortion associated with a huge lymphoid aggregate', 'prominent lymphoid aggregates', 'pannate cell metaplasia']",
"noisy_text": " discuss further down the road. And then the last differential is this. All right. So, Emilio, what would you say about the architecture in this case? Yeah. And then in some areas, there's a little bit of distortion, but what's the distortion associated with? Yeah, a huge lymphoid aggregate. So, this case, as you move along, you'll see a couple of prominent lymphoid aggregates there, here, in the backdrop of preserved lamina propria. So, and then, okay, it might be IBD, especially because there's pannate cell metaplasia, and this is from the rectum. You see the pannate cell metaplasia is showing well?",
"corrected_text": " discuss further down the road. And then the last differential is this. All right. So, Emilio, what would you say about the architecture in this case? Yeah. And then in some areas, there's a little bit of distortion, but what's the distortion associated with? Yeah, a huge lymphoid aggregate. So, this case, as you move along, you'll see a couple of prominent lymphoid aggregates there, here, in the backdrop of preserved lamina propria. So, and then, okay, it might be IBD, especially because there's pannate cell metaplasia, and this is from the rectum. You see the pannate cell metaplasia is showing well?",
"med_umls_ids": "[[{'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'IBD', 'concept_id': 'C0021390', 'confidence': 1.0}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'pannate cell', 'concept_id': 'C0007634', 'confidence': 0.5671628713607788}, {'entity': 'distortion', 'concept_id': 'C0332482', 'confidence': 1.0}, {'entity': 'associated with', 'concept_id': 'C0332281', 'confidence': 1.0}, {'entity': 'lymphoid', 'concept_id': 'C1518071', 'confidence': 1.0}, {'entity': 'aggregate', 'concept_id': 'C0205418', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_767",
"caption_rating": "8"
},
{
"": "1007035",
"caption": "Hemocyanin is present within the histiocytes.",
"image_path": "8S4LeiO6Bbk_image_184b4c7e-959b-4998-8773-3b16a88b79f9.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['lipid vacuoles', 'multinucleated histiocytes', 'ringed siderophages', 'pigmented histiocytes', 'hemocyanin', 'lipid vacuoles', 'multinucleated histiocytes', 'ringed siderophages', 'pigmented histiocytes', 'hemocyanin']",
"noisy_text": " large histiocytes containing lipid. Some of them are multi-nucleated and some of these are actually ringed siderophages. So we see large multi-nucleated histiocytes with a ring of nuclei and they contain not only lipid vacuoles but hemocentaurant. And these are particularly common in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes as suspected is hemocentaurant. If you notice, it's got kind of that golden brown color. If you had a sub-stage condenser or a fine focus knob, you would see that it's somewhat refractile, but unfortunately, we can't use that particular tool when we're looking at scanned images.",
"corrected_text": " large histiocytes containing lipid. Some of them are multinucleated and some of these are actually ringed siderophages. So we see large multinucleated histiocytes with a ring of nuclei and they contain not only lipid vacuoles but hemosiderin. And these are particularly common in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes as suspected is hemosiderin. If you notice, it's got kind of that golden brown color. If you had a sub-stage condenser or a fine focus knob, you would see that it's somewhat refractile, but unfortunately, we can't use that particular tool when we're looking at scanned images.",
"med_umls_ids": "[[{'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'lipid', 'concept_id': 'C0023779', 'confidence': 1.0}, {'entity': 'multinucleated', 'concept_id': 'C0333740', 'confidence': 1.0}, {'entity': 'ringed', 'concept_id': 'C0325501', 'confidence': 0.77345871925354}, {'entity': 'siderophages', 'concept_id': 'C1136253', 'confidence': 0.7251443266868591}], [{'entity': 'Hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}], [{'entity': 'Pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_768",
"caption_rating": "8"
},
{
"": "1007740",
"caption": "Presence of pigmented histiocytes.",
"image_path": "8S4LeiO6Bbk_image_b7c61cc7-68de-4d75-81a3-5cd0960115be.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['collagen balls', 'spindle-shaped cells', 'lipophagic cells', 'ringed siderophages', 'pigmented histiocytes']",
"noisy_text": " these collagen balls that are being surrounded by cells that have a somewhat spindled shape. The nuclei are spindled over our fusiform and they're kind of wrapping around these collagen bundles. In this same area, we can begin to see some lipophagia. So we see these large histiocytes containing lipid. Some of them are multi-nucleated and some of these are actually ringed siderophages. So we see large multi-nucleated histiocytes with a ring of nuclei and they contain not only lipid vacuoles but hemocentaurant. And these are particularly common in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes",
"corrected_text": " these collagen balls that are being surrounded by cells that have a somewhat spindle-shaped. The nuclei are spindle-shaped over our fusiform and they're kind of wrapping around these collagen bundles. In this same area, we can begin to see some lipophagic. So we see these large histiocytes containing lipid. Some of them are multi-nucleated and some of these are actually ringed siderophages. So we see large multinucleated histiocytes with a ring of nuclei and they contain not only lipid vacuoles but hemosiderin. And these are particularly common in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'collagen balls', 'concept_id': 'C0009325', 'confidence': 0.7217866778373718}, {'entity': 'surrounded', 'concept_id': 'C1282914', 'confidence': 1.0}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}], [{'entity': 'Lipophagic cells', 'concept_id': 'C0007584', 'confidence': 0.5962335467338562}, {'entity': 'lipid vacuoles', 'concept_id': 'C1179126', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'ringed', 'concept_id': 'C0325501', 'confidence': 0.77345871925354}, {'entity': 'siderophages', 'concept_id': 'C1136253', 'confidence': 0.7251443266868591}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_769",
"caption_rating": "8"
},
{
"": "1009491",
"caption": "MAC/syringomatous carcinoma typically does not show a lot of mitoses or individual cellular atypia/pleomorphism.",
"image_path": "LlPaENuqzVQ_image_c623b28d-db14-4019-bd1e-3ca9b5092c16.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['Aggregations of cells resembling a syringoma.']",
"noisy_text": " except it's pretty deep, large and deep. Yeah, you're right. So if you look at the individual aggregations of cells, they do look a lot like a syringoma. That's clear staining cells here. They've got these little cuticular areas inside the ducts like you see here. And basically, another name for MAC that I actually like better is syringomatous carcinoma because it looks like a syringoma. And if you look at the individual cells, usually you don't see a lot of mitoses. There's not a lot of individual cellular atypia, not a lot of pleomorphism. It's really a neoplasm that causes problems because of",
"corrected_text": " except it's pretty deep, large and deep. Yeah, you're right. So if you look at the individual aggregations of cells, they do look a lot like a syringoma. That's clear staining cells here. They've got these little cuticular areas inside the ducts like you see here. And basically, another name for MAC that I actually like better is syringomatous carcinoma because it looks like a syringoma. And if you look at the individual cells, usually you don't see a lot of mitoses. There's not a lot of individual cellular atypia, not a lot of pleomorphism. It's really a neoplasm that causes problems because of",
"med_umls_ids": "[[{'entity': 'deep', 'concept_id': 'C0205125', 'confidence': 0.9999999403953552}, {'entity': 'aggregations', 'concept_id': 'C0332621', 'confidence': 0.9210782051086426}, {'entity': 'clear staining cells', 'concept_id': 'C0229473', 'confidence': 0.7975835800170898}, {'entity': 'cuticular areas', 'concept_id': 'C2699479', 'confidence': 0.6761574745178223}, {'entity': 'ducts', 'concept_id': 'C0687028', 'confidence': 1.0}, {'entity': 'syringoma', 'concept_id': 'C0206673', 'confidence': 1.0}], [{'entity': 'MAC', 'concept_id': 'C0009545', 'confidence': 0.9999999403953552}, {'entity': 'mucinous adenocarcinoma', 'concept_id': 'C0007130', 'confidence': 1.0}, {'entity': 'syringomatous carcinoma', 'concept_id': 'C0346027', 'confidence': 1.0}], [{'entity': 'MAC/syringomatous carcinoma', 'concept_id': 'C0346027', 'confidence': 0.7567015886306763}, {'entity': 'mitoses', 'concept_id': 'C0026255', 'confidence': 1.0}, {'entity': 'cellular atypia/pleomorphism', 'concept_id': 'C1707333', 'confidence': 0.6986897587776184}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_770",
"caption_rating": "8"
},
{
"": "1008047",
"caption": "Different nuclear features can be characterized by their appearance, such as vesicular or salt and pepper-like.",
"image_path": "Wiyo6taYRF4_image_8ec240a1-cd99-485c-8390-b36b49277f89.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Hematopathology', 'Neuropathology', 'Cytopathology']",
"roi_text": "['Appearance of heterochromatin and euchromatin in the nucleus.', 'Plasma cells as a reference for classifying nuclear features.', 'Example of vesicular nuclei.']",
"noisy_text": " whether it is vesicular, or it is salt and pepper-like. So these are the different nuclear features which are characterized. And how are you going to differentiate these nuclear features? So let's see some of the nuclear features. And before we move on to describe these features, I think the first thing that we should look at and understand what we are meaning by hyperchromasia and vesicularism is to look at a plasma cell. So a plasma cell is the best example, and it is the best reference where you can classify the different nuclear features. So if you look carefully, the plasma cell has got a cartwheel-like of an appearance. So it is called cartwheel because you see some areas which are darkly strained. So they are the high heterochromatin areas, that is the darkly strained areas. And then in some areas, you see that there is light straining, which is the euchromatin area. So basically, the chromatin that we see in the nucleus is of two types, heterochromatin and euchromatin. Heterochromatin is going to appear darker, whereas the euchromatin will appear lighter on the cell. So similarly, when we see here in this cell nucleus, we see that there are dark and lightly strained areas. And this is what we call as heterochromatin and euchromatin. So suppose in a cell which has mainly heterochromatin, so the entire nucleus is going to look very dark. So those are the cells that we are going to call as hyperchromatic. And if a nucleus is composed of mainly euchromatin, then it will look very lightly strained. And this is what we call as vesicular nuclei. Now to know here what is important is that in a vesicular nuclei, the nucleus is very actively dividing. So if you have not a vesicular nuclei, that in itself will tell you that the cell is very actively proliferating. So let's see one example of vesicular nuclei here. So these",
"corrected_text": " whether it is vesicular, or it is salt and pepper-like. So these are the different nuclear features which are characterized. And how are you going to differentiate these nuclear features? So let's see some of the nuclear features. And before we move on to describe these features, I think the first thing that we should look at and understand what we are meaning by hyperchromasia and vesicular nuclei is to look at a plasma cell. So a plasma cell is the best example, and it is the best reference where you can classify the different nuclear features. So if you look carefully, the plasma cell has got a cartwheel-like of an appearance. So it is called cartwheel because you see some areas which are darkly strained. So they are the high heterochromatin areas, that is the darkly strained areas. And then in some areas, you see that there is light straining, which is the euchromatin area. So basically, the chromatin that we see in the nucleus is of two types, heterochromatin and euchromatin. Heterochromatin is going to appear darker, whereas the euchromatin will appear lighter on the cell. So similarly, when we see here in this cell nucleus, we see that there are dark and lightly strained areas. And this is what we call as heterochromatin and euchromatin. So suppose in a cell which has mainly heterochromatin, so the entire nucleus is going to look very dark. So those are the cells that we are going to call as hyperchromatic. And if a nucleus is composed of mainly euchromatin, then it will look very lightly strained. And this is what we call as vesicular nuclei. Now to know here what is important is that in a vesicular nuclei, the nucleus is very actively dividing. So if you have not a vesicular nuclei, that in itself will tell you that the cell is very actively proliferating. So let's see one example of vesicular nuclei here. So these",
"med_umls_ids": "[[{'entity': 'nuclear', 'concept_id': 'C0521447', 'confidence': 1.0}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'vesicular', 'concept_id': 'C0205378', 'confidence': 1.0}, {'entity': 'salt', 'concept_id': 'C0036140', 'confidence': 1.0}, {'entity': 'pepper-like', 'concept_id': 'C2828772', 'confidence': 0.6665787696838379}], [{'entity': 'Plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'nuclear features', 'concept_id': 'C0521447', 'confidence': 0.6837654709815979}], [{'entity': 'Chromatin', 'concept_id': 'C0008546', 'confidence': 1.0}, {'entity': 'nucleus', 'concept_id': 'C0007610', 'confidence': 1.0}, {'entity': 'heterochromatin', 'concept_id': 'C0019397', 'confidence': 1.0}, {'entity': 'euchromatin', 'concept_id': 'C0059882', 'confidence': 1.0}], [{'entity': 'Hyperchromatic cells', 'concept_id': 'C0333911', 'confidence': 0.823300302028656}, {'entity': 'heterochromatin', 'concept_id': 'C0019397', 'confidence': 1.0}, {'entity': 'very dark', 'concept_id': 'C0332582', 'confidence': 0.8206402063369751}], [{'entity': 'Vesicular nuclei', 'concept_id': 'C2325471', 'confidence': 0.7651268839836121}, {'entity': 'cell', 'concept_id': 'C0007634', 'confidence': 1.0}, {'entity': 'dividing', 'concept_id': 'C0332849', 'confidence': 1.0}, {'entity': 'euchromatin', 'concept_id': 'C0059882', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1152.0",
"id": "test_771",
"caption_rating": "8"
},
{
"": "1004712",
"caption": "Describes the physical characteristics of fibrofolliculoma, including a relatively dense fibrous stroma and no clefting between the lesion.",
"image_path": "LlPaENuqzVQ_image_6b49a2eb-80ea-4e78-a018-03325c327ea5.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['No clefting between the lesion', 'No clefting between the lesion']",
"noisy_text": " and the follicular elements, as well as the perifollicular connective tissue. And it's kind of got this pretty characteristic, it's kind of a relatively dense fibrous stroma. It's not loose and mixoid like the stroma you see around the basal cell carcinoma. Notice that there's no clefting between this, like we see with the basal cell carcinoma. So this is fibrofolliculoma. There's two other lesions that are associated with that. They're really the same lesion. In other words, if you just get mostly fibrous with a little teensy, tiny strand of epithelium left, that's either going to be a trichodyscoma or a perifollicular fibroma. And those are really, they're probably really all the same lesion, just they kind of look a little bit different. So that's kind of important to know that from the",
"corrected_text": " and the follicular elements, as well as the perifollicular connective tissue. And it's kind of got this pretty characteristic, it's kind of a relatively dense fibrous stroma. It's not loose and mixoid like the stroma you see around the basal cell carcinoma. Notice that there's no clefting between this, like we see with the basal cell carcinoma. So this is fibrofolliculoma. There's two other lesions that are associated with that. They're really the same lesion. In other words, if you just get mostly fibrous with a little teensy, tiny strand of epithelium left, that's either going to be a trichodiscoma or a perifollicular fibroma. And those are really, they're probably really all the same lesion, just they kind of look a little bit different. So that's kind of important to know that from the",
"med_umls_ids": "[[{'entity': 'Describes', 'concept_id': 'C1552738', 'confidence': 0.7625278830528259}, {'entity': 'physical characteristics', 'concept_id': 'C1521970', 'confidence': 0.8302092552185059}, {'entity': 'fibrofolliculoma', 'concept_id': 'C0346011', 'confidence': 1.0}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}, {'entity': 'clefting', 'concept_id': 'C4021813', 'confidence': 0.8906428217887878}, {'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}], [{'entity': 'Trichodiscoma', 'concept_id': 'C0346011', 'confidence': 1.0}, {'entity': 'perifollicular fibroma', 'concept_id': 'C1704236', 'confidence': 1.0}, {'entity': 'lesions', 'concept_id': 'C0221198', 'confidence': 1.0}, {'entity': 'fibrofolliculoma', 'concept_id': 'C0346011', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_772",
"caption_rating": "8"
},
{
"": "1004670",
"caption": "Inflammation is a common result of chemical gastritis.",
"image_path": "r7OA0Trj5hQ_image_c6eb73a1-9f9f-4e7a-911d-5342b8bef44b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['lamina propria edema', 'muscularis mucosa', 'neutrophils', 'eosinophils', 'stomach', 'esophagus', 'enteritis', 'colitis', 'lamina propria edema', 'muscularis mucosa', 'neutrophils', 'eosinophils', 'stomach', 'esophagus', 'enteritis', 'colitis']",
"noisy_text": " Lamina propria edema and muscularis mucosa coming into the lamina propria. These are the three criterias. When you see it in the anterobiopsy, think of chemical gastritis that can be seen in biliary reflux or NSAID use. Lot of inflammation results. Remember I told you if you see more than five neutrophils, more than five eosinophils sitting in the lamina propria or more than 15 eosinophils per high power field, that is a eosinophilic gastritis, if it is from the stomach. If it is esophagus, it is eosinophilic esophagitis, eosinophilic entritis, eosinophilic colitis. So eosinophilic",
"corrected_text": " Lamina propria edema and muscularis mucosa coming into the lamina propria. These are the three criterias. When you see it in the antral biopsy, think of chemical gastritis that can be seen in biliary reflux or NSAID use. Lot of inflammation results. Remember I told you if you see more than five neutrophils, more than five eosinophils sitting in the lamina propria or more than 15 or more eosinophils per high power field, that is a eosinophilic gastritis, if it is from the stomach. If it is esophagus, it is eosinophilic esophagitis, eosinophilic enteritis, eosinophilic colitis. So eosinophilic",
"med_umls_ids": "[[{'entity': 'Lamina propria edema', 'concept_id': 'C1179187', 'confidence': 0.7593827247619629}, {'entity': 'muscularis mucosa', 'concept_id': 'C0225357', 'confidence': 0.9999998807907104}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'criteria', 'concept_id': 'C0243161', 'confidence': 0.9999998807907104}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}], [{'entity': 'Inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}], [{'entity': 'Eosinophilic gastritis', 'concept_id': 'C0267154', 'confidence': 1.0}, {'entity': 'diagnosed', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}], [{'entity': 'Eosinophilic esophagitis', 'concept_id': 'C0341106', 'confidence': 0.9999999403953552}, {'entity': 'eosinophilic enteritis', 'concept_id': 'C1262481', 'confidence': 1.0}, {'entity': 'eosinophilic colitis', 'concept_id': 'C0267448', 'confidence': 1.0}, {'entity': 'diagnoses', 'concept_id': 'C0011900', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_773",
"caption_rating": "7"
},
{
"": "1006302",
"caption": "Another type of dermatofibroma with large atypical cells or monster cells can simulate cancer.",
"image_path": "udoW6VSqsm4_image_2a63f541-31ba-4776-91c6-846c7a4b6c86.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['Areas with hemosiderin', 'Areas with foamy appearance', 'Lipid-laden cells in cellular dermatofibroma']",
"noisy_text": " Like there are areas where there was hemosiderin. It's kind of hard to see from here, but I found some areas where there was hemosiderin, but some areas that were also a little foamy. Yeah, I'd say a little bit foamy. Scale of one to ten, that's probably about a ten with regard to foaming. So yeah, they're very lipidized. So this would be like a cellular dermatofibroma with lipidization. There's another type of dermatofibroma where you can see large atypical cells, or dermatofibroma with monster cells. Those can simulate cancer. This one didn't really have as many of those kinds of cells. Yeah, so",
"corrected_text": " Like there are areas where there was hemosiderin. It's kind of hard to see from here, but I found some areas where there was hemosiderin, but some areas that were also a little foamy. Yeah, I'd say a little bit foamy. Scale of one to ten, that's probably about a ten with regard to foaming. So yeah, they're very lipid-laden. So this would be like a cellular dermatofibroma with lipid accumulation. There's another type of dermatofibroma where you can see large atypical cells, or dermatofibroma with monster cells. Those can simulate cancer. This one didn't really have as many of those kinds of cells. Yeah, so",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'hemosiderin', 'concept_id': 'C0019113', 'confidence': 1.0}, {'entity': 'lipid-laden cells', 'concept_id': 'C0007584', 'confidence': 0.5060436129570007}, {'entity': 'cellular dermatofibroma', 'concept_id': 'C0002991', 'confidence': 0.833601713180542}, {'entity': 'lipid accumulation', 'concept_id': 'C0333574', 'confidence': 1.0}], [{'entity': 'dermatofibroma', 'concept_id': 'C0002991', 'confidence': 1.0}, {'entity': 'atypical cells', 'concept_id': 'C0333865', 'confidence': 1.0}, {'entity': 'monster cells', 'concept_id': 'C0007584', 'confidence': 0.7091032862663269}, {'entity': 'simulate', 'concept_id': 'C0284447', 'confidence': 0.9999998807907104}, {'entity': 'cancer', 'concept_id': 'C0006826', 'confidence': 0.9999998807907104}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_774",
"caption_rating": "7"
},
{
"": "1007589",
"caption": "Pleomorphism and mitotic activity are uncommon in this tumor.",
"image_path": "QDb68_G1HR4_image_2b9d634a-4aee-4dd1-9026-7dbebb1015fc.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " sometimes pleomorphism is seen it's just really uncommon. Also mitotic activity I don't think I mentioned it yet mitoses are usually very very low in this tumor if you see I think the general rule is if you're unless you're a sarcoma pathology expert. And even then if I see even as a sarcoma pathologist if I see marked pleomorphism a lot of mitotic activity other features like that I'm probably going to send the case for molecular testing just to be totally sure that it's a low-grade fiber myxoid sarcoma and not some other mimic. So experts",
"corrected_text": " sometimes pleomorphism is seen it's just really uncommon. Also mitotic activity I don't think I mentioned it yet mitoses are usually very very low in this tumor if you see I think the general rule is if you're unless you're a sarcoma pathology expert. And even then if I see even as a sarcoma pathologist if I see marked pleomorphism a lot of mitotic activity other features like that I'm probably going to send the case for molecular testing just to be totally sure that it's a low-grade fiber myxoid sarcoma and not some other mimic. So experts",
"med_umls_ids": "[[{'entity': 'Pleomorphism', 'concept_id': 'C0032219', 'confidence': 1.0}, {'entity': 'mitotic activity', 'concept_id': 'C1334779', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}], [{'entity': 'Mitoses', 'concept_id': 'C0026255', 'confidence': 1.0}], [{'entity': 'Molecular testing', 'concept_id': 'C1521991', 'confidence': 0.8002516627311707}, {'entity': 'pleomorphism', 'concept_id': 'C0032219', 'confidence': 1.0}, {'entity': 'mitotic activity', 'concept_id': 'C1334779', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_775",
"caption_rating": "8"
},
{
"": "1008561",
"caption": "Mitosis and stratification are observed.",
"image_path": "r7OA0Trj5hQ_image_c3ffa8b2-387b-4d35-b219-84a9f742c5d7.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Loss of mucin', 'Loss of cellular polarity', 'Nuclear stratification', 'Mitosis', 'Apoptosis', 'Loss of mucin', 'Loss of cellular polarity', 'Nuclear stratification', 'Mitosis', 'Apoptosis']",
"noisy_text": " This is proliferative. With ATP or without ATP? With ATP? With invasion or without invasion? In this field, we cannot judge the invasion. So this is a proliferation with ATP. And see the glands stratify. And loss of mucin or less of mucin. And there is loss of polarity. Look at this nuclei running like in this direction. Look at this nuclei running in this direction. So clearly, loss of polarity. And the nuclear stratification is reaching the top of the epithelium, marked apoptosis. It's too thick to see the mitosis, but here you can see the mitosis. So this is stratification, loss of mucin, mitosis, apoptosis. So this",
"corrected_text": " This is proliferative. With ATP or without ATP? With ATP? With invasion or without invasion? In this field, we cannot judge the invasion. So this is a proliferation with ATP. And see the glands stratify. And loss of mucin or less of mucin. And there is loss of polarity. Look at this nuclei running like in this direction. Look at this nuclei running in this direction. So clearly, loss of polarity. And the nuclear stratification is reaching the top of the epithelium, marked apoptosis. It's too thick to see the mitosis, but here you can see the mitosis. So this is stratification, loss of mucin, mitosis, apoptosis. So this",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'proliferative cells', 'concept_id': 'C0334094', 'confidence': 0.8005025386810303}, {'entity': 'ATP', 'concept_id': 'C0001480', 'confidence': 1.0}, {'entity': 'hyperplastic glands', 'concept_id': 'C0020507', 'confidence': 0.7789753675460815}], [{'entity': 'Loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'mucin', 'concept_id': 'C0026682', 'confidence': 1.0}, {'entity': 'cellular polarity', 'concept_id': 'C0085304', 'confidence': 1.0}], [{'entity': 'Nuclear', 'concept_id': 'C0521447', 'confidence': 1.0}, {'entity': 'stratification', 'concept_id': 'C1514983', 'confidence': 1.0}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'apoptosis', 'concept_id': 'C0162638', 'confidence': 1.0}], [{'entity': 'Mitosis', 'concept_id': 'C0026255', 'confidence': 0.9999998807907104}, {'entity': 'stratification', 'concept_id': 'C1514983', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_776",
"caption_rating": "7"
},
{
"": "1004456",
"caption": "Goblet cells in the stomach indicate intestinal metaplasia.",
"image_path": "r7OA0Trj5hQ_image_8b04be78-c890-4686-bd2f-aed9e7558f4c.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['H. pylori in the oil immersion', 'Goblet cells in the stomach', 'Mucin in the stomach is neutral', 'Goblet cells in the stomach', 'Mucin in the stomach is neutral']",
"noisy_text": " Here, now we are coming to cytology. You see in the intra-luminal area or in the lumen, you see a lot of comma-shaped rods sitting on the epithelium, not going into the epithelium. So these are all the H. pylori in the oil immersion. Here, the surface epithelium shows goblet cells, and these are all biopsies from the stomach. So when you see goblet cells in the stomach, it is intestinal metaplasia. Another thing you have to remember, the stomach is having an acid milieu, acid environment, but the mucin in the stomach is neutral, whereas the intestinal mucin is acidic. That's why in PAS, the acidic mucin is taking the asian blue color, whereas the",
"corrected_text": " Here, now we are coming to cytology. You see in the luminal area or in the lumen, you see a lot of comma-shaped rods sitting on the epithelium, not going into the epithelium. So these are all the H. pylori in the oil immersion. Here, the surface epithelium shows goblet cells, and these are all biopsies from the stomach. So when you see goblet cells in the stomach, it is intestinal metaplasia. Another thing you have to remember, the stomach is having an acid milieu, acid environment, but the mucin in the stomach is neutral, whereas the intestinal mucin is acidic. That's why in PAS, the acidic mucin is taking the asian blue color, whereas the",
"med_umls_ids": "[[{'entity': 'Cytological', 'concept_id': 'C0205471', 'confidence': 0.9999998807907104}, {'entity': 'stomach biopsies', 'concept_id': 'C0005558', 'confidence': 0.7603482604026794}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'H. pylori', 'concept_id': 'C0079488', 'confidence': 1.0}, {'entity': 'luminal area', 'concept_id': 'C0524462', 'confidence': 0.7778207659721375}, {'entity': 'lumen', 'concept_id': 'C0524461', 'confidence': 0.9999998807907104}], [{'entity': 'Goblet cells', 'concept_id': 'C0506994', 'confidence': 0.9999999403953552}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'intestinal metaplasia', 'concept_id': 'C0334037', 'confidence': 1.0}], [{'entity': 'Difference', 'concept_id': 'C1705241', 'confidence': 1.0}, {'entity': 'acidity', 'concept_id': 'C0001128', 'confidence': 1.0}, {'entity': 'mucin', 'concept_id': 'C0026682', 'confidence': 1.0}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'intestine', 'concept_id': 'C0021853', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_777",
"caption_rating": "8"
},
{
"": "1006888",
"caption": "Nuclei in hepatocytes are lightly strained and prominent.",
"image_path": "Wiyo6taYRF4_image_a342de41-b6bb-4adc-849c-89687471412d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Hematopathology', 'Neuropathology', 'Cytopathology']",
"roi_text": "['Liver cell structure with hepatocytes and normal vesicular nuclei', 'Cells in the sinusoid with dark straining nuclei.']",
"noisy_text": " that the nucleus is lightly strained, and it is showing a prominent nuclei. So this is what we will describe as vesicular nuclei with the prominent nuclei. Now, this is an example which is showing the liver cell in structure. So these are the hepatocytes, and which are showing the normal nuclei in a hepatocyte is vesicular. And if you compare these cells with the cells which are there in the sinusoid, they're looking very dark. So these are the dark straining nuclei. And in most of the heterochromatic nuclei, you will not see any nuclei. Why you",
"corrected_text": " that the nucleus is lightly strained, and it is showing a prominent nuclei. So this is what we will describe as vesicular nuclei with the prominent nuclei. Now, this is an example which is showing the liver cell in structure. So these are the hepatocytes, and which are showing the normal nuclei in a hepatocyte is vesicular. And if you compare these cells with the cells which are there in the sinusoid, they're looking very dark. So these are the dark straining nuclei. And in most of the heterochromatin, you will not see any nuclei. Why you",
"med_umls_ids": "[[{'entity': 'liver cell', 'concept_id': 'C0227525', 'confidence': 1.0}, {'entity': 'hepatocytes', 'concept_id': 'C0227525', 'confidence': 0.9999999403953552}, {'entity': 'vesicular nuclei', 'concept_id': 'C2325471', 'confidence': 0.7651268839836121}], [{'entity': 'Nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'hepatocytes', 'concept_id': 'C0227525', 'confidence': 0.9999999403953552}, {'entity': 'strained', 'concept_id': 'C0080194', 'confidence': 1.0}, {'entity': 'prominent', 'concept_id': 'C0205402', 'confidence': 0.9999999403953552}], [{'entity': 'Cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'sinusoid', 'concept_id': 'C0682624', 'confidence': 0.9999999403953552}, {'entity': 'dark straining', 'concept_id': 'C0442694', 'confidence': 0.6908934712409973}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}], [{'entity': 'heterochromatin', 'concept_id': 'C0019397', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1152.0",
"id": "test_778",
"caption_rating": "8"
},
{
"": "1008979",
"caption": "Intraductal carcinoma of the prostate is usually associated with invasive cancer.",
"image_path": "iklRyY1nBIE_image_544693de-c787-4ed3-a400-43ea5365d478.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['intraductal carcinoma', 'cribriform glands', 'basal cells']",
"noisy_text": " And I'll demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues, it's very important to make that point clear. So this is the corresponding to the case I showed you. So let me just show you a couple more examples of introductal carcinoma of the prostate. So this case, this one looks a little different. You don't have, I mean, looking at the HNE, you may assume all this is invasive. But you'll probably be surprised when you see the corresponding pain cocktail. What you can see here are cribriform glands. Again, it's a busy, busy core, lots of glands. And when you see tumor cells or glands at the edge of a core, at the edge of a core like this, that's usually bats. And usually high-grade tumors that do that. But when you see what we're seeing here, a lot of cribriform glands. And if you go a bit closer, you can see a hint of basal cells around most of them. So we'll",
"corrected_text": " And I'demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues, it's very important to make that point clear. So this is the corresponding to the case I showed you. So let me just show you a couple more examples of introductal carcinoma of the prostate. So this case, this one looks a little different. You don't have, I mean, looking at the HNE, you may assume all this is invasive. But you'll probably be surprised when you see the corresponding pain cocktail. What you can see here are cribriform glands. Again, it's a busy, busy core, lots of glands. And when you see tumor cells or glands at the edge of a core, at the edge of a core like this, that's usually bats. And usually high-grade tumors that do that. But when you see what we're seeing here, a lot of cribriform glands. And if you go a bit closer, you can see a hint of basal cells around most of them. So we'll",
"med_umls_ids": "[[{'entity': 'Intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'associated with', 'concept_id': 'C0332281', 'confidence': 1.0}, {'entity': 'invasive cancer', 'concept_id': 'C0677898', 'confidence': 1.0}], [{'entity': 'Cribriform glands', 'concept_id': 'C1285092', 'confidence': 0.6162902116775513}, {'entity': 'edge', 'concept_id': 'C0205154', 'confidence': 1.0}, {'entity': 'core', 'concept_id': 'C0444669', 'confidence': 0.9999999403953552}, {'entity': 'high-grade tumors', 'concept_id': 'C0027651', 'confidence': 0.5436328053474426}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'basal cells', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'cribriform glands', 'concept_id': 'C1285092', 'confidence': 0.6162902116775513}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_779",
"caption_rating": "9"
},
{
"": "1007158",
"caption": "High grade dysplasia and malignant glands seen in the muscle bundle.",
"image_path": "r7OA0Trj5hQ_image_5c60bb1a-0cfa-4ae1-98cc-acbc869ca38e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Chronic atrophic gastritis', 'Intestinal metaplasia', 'Muscularization of the lamina propria', 'Muscularis propria acts like a barrier', 'High grade dysplasia', 'Malignant glands going into the muscle bundle', 'Chronic atrophic gastritis', 'Intestinal metaplasia', 'Muscularization of the lamina propria', 'Muscularis propria acts like a barrier', 'High grade dysplasia', 'Malignant glands going into the muscle bundle']",
"noisy_text": " So this is chronic atrophic gastritis with intestinal metaplasia with muscularization of the lamina propria. More than one pathology involved in this biopsy. Plastic changes seen above are known as TIS. Once they cross the muscular ischemicosa, then only they are eligible for T1. So muscular ischemicosa acts like a barrier. Here, in this picture, you can see the muscular ischemicosa acts like a barrier. So this is only high grade dysplasia. Whereas here, you can see the malignant glands going into the muscle bundle. And glands, malignant glands are seen on both sides of the muscle. So this",
"corrected_text": " So this is chronic atrophic gastritis with intestinal metaplasia with muscularization of the lamina propria. More than one pathology involved in this biopsy. Plastic changes seen above are known as TIS. Once they cross the muscularis propria, then only they are eligible for T1. So muscularis propria acts like a barrier. Here, in this picture, you can see the muscularis propria acts like a barrier. So this is only high grade dysplasia. Whereas here, you can see the malignant glands going into the muscle bundle. And glands, malignant glands are seen on both sides of the muscle. So this",
"med_umls_ids": "[[{'entity': 'Chronic atrophic gastritis', 'concept_id': 'C0017154', 'confidence': 1.0}, {'entity': 'intestinal metaplasia', 'concept_id': 'C0334037', 'confidence': 1.0}, {'entity': 'muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}], [{'entity': 'Plastic changes', 'concept_id': 'C0392747', 'confidence': 0.7598782777786255}, {'entity': 'TIS', 'concept_id': 'C0475413', 'confidence': 1.0}], [{'entity': 'Muscularis propria', 'concept_id': 'C0225358', 'confidence': 1.0}, {'entity': 'barrier', 'concept_id': 'C1706912', 'confidence': 1.0}], [{'entity': 'High grade', 'concept_id': 'C0205082', 'confidence': 1.0}, {'entity': 'malignant glands', 'concept_id': 'C0205282', 'confidence': 0.7218497395515442}, {'entity': 'muscle bundle', 'concept_id': 'C0504095', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_780",
"caption_rating": "9"
},
{
"": "1008315",
"caption": "The presence of a large cellular fibrohistiocytic infiltrate with collagen trapping and ring siderophages is indicative of a hemosiderotic or aneurysmal type of dermatofibroma, also known as a sclerosing hemangioma variant of a dermatofibroma. These lesions have a tendency to persist or recur if incompletely excised.",
"image_path": "8S4LeiO6Bbk_image_e17ce632-d8cc-4545-8a00-2cd984386fa0.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Large cellular fibrohistiocytic infiltrate with collagen trapping and ring siderophages', 'Hemosiderotic or aneurysmal type of dermatofibroma', 'Punch biopsy specimen', 'Large cellular fibrohistiocytic infiltrate with collagen trapping and ring siderophages', 'Hemosiderotic or aneurysmal type of dermatofibroma', 'Punch biopsy specimen']",
"noisy_text": " know, we're not seeing any necrosis or an appreciable number of mitotic figures. And this large cellular fibrohystic-acidic infiltrate, again with the collagen trapping and ring siderophages out of the periphery, seems to be compressing the fat. And the constellation of features in these sections is pathognomonic, of course, or a hemociderotic or aneurysmal type of dermatofibroma, also known as a sclerosing hemangioma variant of a dermatofibroma. This is a type of cellular dermatofibroma. These lesions can get quite large and if incompletely excised do have a tendency to persist or recur. So good idea to completely excise these because they're certainly not going to go away on their own. A classic example, very commonly asked on boards and usually spoilers that you could expect in a question given this slide would include things like a blue nevus or melanoma or even nodular cap issues. So be familiar with the features of the hemociderotic variant of a dermatofibroma. Moving on to slide number five. This was kind of a cool case. We have a bisected punch biopsy specimen here. If we move into higher power, we can see that the epidermis",
"corrected_text": " know, we're not seeing any necrosis or an appreciable number of mitotic figures. And this large cellular fibrohystic-acidic infiltrate, again with the collagen trapping and ring siderophages out of the periphery, seems to be compressing the fat. And the constellation of features in these sections is pathognomonic, of course, or a hemosiderotic or aneurysmal type of dermatofibroma, also known as a sclerosing hemangioma variant of a dermatofibroma. This is a type of cellular dermatofibroma. These lesions can get quite large and if incompletely excised do have a tendency to persist or recur. So good idea to completely excise these because they're certainly not going to go away on their own. A classic example, very commonly asked on boards and usually spoilers that you could expect in a question given this slide would include things like a blue nevus or melanoma or even nodular cap issues. So be familiar with the features of the hemosiderotic variant of dermatofibroma of a dermatofibroma. Moving on to slide number five. This was kind of a cool case. We have a bisected punch biopsy specimen here. If we move into higher power, we can see that the epidermis",
"med_umls_ids": "[[{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'cellular fibrohistiocytic infiltrate', 'concept_id': 'C0019618', 'confidence': 0.7253735065460205}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'trapping', 'concept_id': 'C0282665', 'confidence': 0.8904784917831421}, {'entity': 'ring siderophages', 'concept_id': 'C1136253', 'confidence': 0.6553963422775269}, {'entity': 'hemosiderotic', 'concept_id': 'C0019114', 'confidence': 0.7758374810218811}, {'entity': 'aneurysmal type', 'concept_id': 'C0439651', 'confidence': 0.8459930419921875}, {'entity': 'dermatofibroma', 'concept_id': 'C0002991', 'confidence': 1.0}, {'entity': 'sclerosing', 'concept_id': 'C0036426', 'confidence': 0.833010733127594}, {'entity': 'hemangioma', 'concept_id': 'C0018916', 'confidence': 1.0}, {'entity': 'variant', 'concept_id': 'C0205419', 'confidence': 1.0}, {'entity': 'dermatofibroma', 'concept_id': 'C0002991', 'confidence': 1.0}, {'entity': 'lesions', 'concept_id': 'C0221198', 'confidence': 1.0}, {'entity': 'excised', 'concept_id': 'C1444670', 'confidence': 0.7215964794158936}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_781",
"caption_rating": "9"
},
{
"": "1008362",
"caption": "The histopathological findings include lymphocytes, dilated vessels, papillomatosis, and epidermal hyperplasia.",
"image_path": "8S4LeiO6Bbk_image_525c93d7-23ef-4276-b0ce-6a5662640cb6.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['columns and mounds of parakeratosis within the stratum corneum', 'dyskeratotic cells within the underlying epidermis', 'papillary dermis between these zones', 'no identifiable foam cells present within the papillary dermis', 'columns and mounds of parakeratosis within the stratum corneum', 'dyskeratotic cells within the underlying epidermis', 'papillary dermis between these zones', 'no identifiable foam cells present within the papillary dermis']",
"noisy_text": " and if we move to higher power, we can confirm these findings. Lymphocytes, dilated vessels, papillomatosis, and epidermal hyperplasia. There are discrete columns and mounds of pericaratosis within the stratum corneum and some dyskeratotic cells within the underlying epidermis. One of the things when one sees these these columns of bright pink pericaratosis that one might think about would be a verruciform xanthoma because you'll remember we tend to get these vertical columns of pericaratosis kind of extending down to a v-shaped imagination of the epidermis. We have that here but one thing that we don't have here that one typically sees in a verruciform xanthoma is the presence of neutrophils and mixed with the pericaratotic cells and also if we look in the dermal papillae between these zones, there are really no identifiable foam cells present within the dermal papillae. Looking over at the far edge of this",
"corrected_text": " and if we move to higher power, we can confirm these findings. Lymphocytes, dilated vessels, papillomatosis, and epidermal hyperplasia. There are discrete columns and mounds of parakeratosis within the stratum corneum and some dyskeratotic cells within the underlying epidermis. One of the things when one sees these these columns of bright pink parakeratosis that one might think about would be a verruciform xanthoma because you'remember we tend to get these vertical columns of pericaratosis kind of extending down to a v-shaped imagination of the epidermis. We have that here but one thing that we don't have here that one typically sees in a verruciform xanthoma is the presence of neutrophils and mixed with the parakeratotic cells and also if we look in the dermal papillae between these zones, there are really no identifiable foam cells present within the dermal papillae. Looking over at the far edge of this",
"med_umls_ids": "[[{'entity': 'histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'findings', 'concept_id': 'C2607943', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'dilated vessels', 'concept_id': 'C0424830', 'confidence': 0.8255378603935242}, {'entity': 'papillomatosis', 'concept_id': 'C0205875', 'confidence': 1.0}, {'entity': 'epidermal hyperplasia', 'concept_id': 'C0263641', 'confidence': 1.0}], [{'entity': 'discrete columns', 'concept_id': 'C0227428', 'confidence': 0.6879350543022156}, {'entity': 'mounds', 'concept_id': 'C2717795', 'confidence': 0.736616313457489}, {'entity': 'parakeratosis', 'concept_id': 'C0030436', 'confidence': 1.0}, {'entity': 'stratum corneum', 'concept_id': 'C0221921', 'confidence': 1.0}, {'entity': 'dyskeratotic cells', 'concept_id': 'C1512098', 'confidence': 0.8970272541046143}, {'entity': 'epidermis', 'concept_id': 'C0014520', 'confidence': 1.0}], [{'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'foam cells', 'concept_id': 'C0016390', 'confidence': 1.0}, {'entity': 'verruciform xanthoma', 'concept_id': 'C0346054', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_782",
"caption_rating": "9"
},
{
"": "1004632",
"caption": "The lesion tends to occur along the ulnar aspect of the fifth digit and can be bilateral.",
"image_path": "8S4LeiO6Bbk_image_3be82740-e995-4d6e-a807-c3fca940d56f.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['nerve fascicles', 'spindle-shaped cells', 'rudimentary supernumerary digit', 'ulnar aspect of the fifth digit', 'acquired digital fibroma', 'acquired digital fibrokeratoma', 'trichilemmal cyst']",
"noisy_text": " core here we've got several well-defined nerve fascicles and the spindled cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions of course tend to occur along the ulnar eye aspect of the fifth digit. They're not infrequently bilateral and the key differential here of course is an acquired digital fibroma or an acquired digital fibrocarotoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if",
"corrected_text": " core here we've got several well-defined nerve fascicles and the spindle cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions of course tend to occur along the ulnar eye aspect of the fifth digit. They're not infrequently bilateral and the key differential here of course is an acquired digital fibroma or an acquired digital fibrokeratoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if",
"med_umls_ids": "[[{'entity': 'Well-defined nerve fascicles', 'concept_id': 'C1185741', 'confidence': 0.5682494640350342}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'S100', 'concept_id': 'C3273837', 'confidence': 1.0}, {'entity': 'SOX10', 'concept_id': 'C1420317', 'confidence': 0.9999998807907104}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'rudimentary supernumerary digit', 'concept_id': 'C0152427', 'confidence': 0.8142021894454956}], [{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'ulnar', 'concept_id': 'C0442044', 'confidence': 1.0}, {'entity': 'aspect', 'concept_id': 'C1547011', 'confidence': 1.0}, {'entity': 'fifth digit', 'concept_id': 'C0230403', 'confidence': 0.912693440914154}, {'entity': 'bilateral', 'concept_id': 'C0238767', 'confidence': 1.0}], [{'entity': 'differential diagnosis', 'concept_id': 'C0011906', 'confidence': 1.0}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}, {'entity': 'digital fibroma', 'concept_id': 'C4538745', 'confidence': 0.8997364640235901}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}], [{'entity': 'Trichilemmal cyst', 'concept_id': 'C2266788', 'confidence': 1.0}, {'entity': 'biopsy specimen', 'concept_id': 'C0677862', 'confidence': 1.0}, {'entity': 'slide number', 'concept_id': 'C3828004', 'confidence': 0.8261933326721191}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_783",
"caption_rating": "8"
},
{
"": "1007043",
"caption": "The lesion is a small benign papule with dilated blood vessels and proliferating sebaceous lobules. It has two components: a fibrous component and an epithelial component, which includes an epithelial sebaceous gland.",
"image_path": "LlPaENuqzVQ_image_92ae2460-057d-4e1a-8713-0ac7f340a424.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['dilated blood vessels', 'sebaceous lobules', 'fibrous component', 'epithelial component', 'epithelial sebaceous gland', 'teensy small follicle']",
"noisy_text": " And then there's some dilated blood vessels and whatnot, background sebaceous lobules that are proliferating. This may be kind of an incipient one of them, but this is what we're looking at here. So it's a small teensy tiny papule. And it's, if it's a neoplasm, it's got a two components to it. It's got a fibrous component, like right here. And then it's also got this epithelial component. What do you think this, what kind of differentiation are we looking at right here? Right, I feel it, right. So this is epithelial sebaceous gland. That's epithelium, little teensy small follicle right there. What's this? Is it closer to this or this? Sorry. Like, it",
"corrected_text": " And then there's some dilated blood vessels and whatnot, background sebaceous lobules that are proliferating. This may be kind of an incipient one of them, but this is what we're looking at here. So it's a small teensy tiny papule. And it's, if it's a neoplasm, it's got a two components to it. It's got a fibrous component, like right here. And then it's also got this epithelial component. What do you think this, what kind of differentiation are we looking at right here? Right, I feel it, right. So this is epithelial sebaceous gland. That's epithelium, little teensy small follicle right there. What's this? Is it closer to this or this? Sorry. Like, it",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'benign papule', 'concept_id': 'C0205183', 'confidence': 0.7019047737121582}, {'entity': 'dilated blood vessels', 'concept_id': 'C0424830', 'confidence': 1.0}, {'entity': 'proliferating sebaceous lobules', 'concept_id': 'C0221946', 'confidence': 0.7654090523719788}, {'entity': 'components', 'concept_id': 'C0449432', 'confidence': 1.0}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}, {'entity': 'epithelial component', 'concept_id': 'C1707933', 'confidence': 0.8783122897148132}, {'entity': 'epithelial sebaceous gland', 'concept_id': 'C0036505', 'confidence': 0.7906183004379272}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_784",
"caption_rating": "9"
},
{
"": "1005822",
"caption": "Trichilemmal cyst biopsy specimen on slide number seven.",
"image_path": "8S4LeiO6Bbk_image_05eec250-fd22-4ed8-93df-a011dc2c30f2.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['nerve fascicles', 'spindle-shaped cells', 'rudimentary supernumerary digit', 'ulnar aspect of the fifth digit', 'acquired digital fibroma', 'acquired digital fibrokeratoma', 'trichilemmal cyst', 'nerve fascicles', 'spindle-shaped cells', 'rudimentary supernumerary digit', 'ulnar aspect of the fifth digit', 'acquired digital fibroma', 'acquired digital fibrokeratoma', 'trichilemmal cyst', 'nerve fascicles', 'spindle-shaped cells', 'rudimentary supernumerary digit', 'ulnar aspect of the fifth digit', 'acquired digital fibroma', 'acquired digital fibrokeratoma', 'trichilemmal cyst']",
"noisy_text": " core here we've got several well-defined nerve fascicles and the spindled cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions of course tend to occur along the ulnar eye aspect of the fifth digit. They're not infrequently bilateral and the key differential here of course is an acquired digital fibroma or an acquired digital fibrocarotoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if",
"corrected_text": " core here we've got several well-defined nerve fascicles and the spindle cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions of course tend to occur along the ulnar eye aspect of the fifth digit. They're not infrequently bilateral and the key differential here of course is an acquired digital fibroma or an acquired digital fibrokeratoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if",
"med_umls_ids": "[[{'entity': 'Well-defined nerve fascicles', 'concept_id': 'C1185741', 'confidence': 0.5682494640350342}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'S100', 'concept_id': 'C3273837', 'confidence': 1.0}, {'entity': 'SOX10', 'concept_id': 'C1420317', 'confidence': 0.9999998807907104}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'rudimentary supernumerary digit', 'concept_id': 'C0152427', 'confidence': 0.8142021894454956}], [{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'ulnar', 'concept_id': 'C0442044', 'confidence': 1.0}, {'entity': 'aspect', 'concept_id': 'C1547011', 'confidence': 1.0}, {'entity': 'fifth digit', 'concept_id': 'C0230403', 'confidence': 0.912693440914154}, {'entity': 'bilateral', 'concept_id': 'C0238767', 'confidence': 1.0}], [{'entity': 'differential diagnosis', 'concept_id': 'C0011906', 'confidence': 1.0}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}, {'entity': 'digital fibroma', 'concept_id': 'C4538745', 'confidence': 0.8997364640235901}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}], [{'entity': 'Trichilemmal cyst', 'concept_id': 'C2266788', 'confidence': 1.0}, {'entity': 'biopsy specimen', 'concept_id': 'C0677862', 'confidence': 1.0}, {'entity': 'slide number', 'concept_id': 'C3828004', 'confidence': 0.8261933326721191}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_785",
"caption_rating": "8"
},
{
"": "1005344",
"caption": "Disseminated GA in older individuals may be a perineoplastic process.",
"image_path": "udoW6VSqsm4_image_24d23039-b3f2-46db-8ca2-24721d0b7540.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['small individual papules', 'central crust', 'perioral skin', 'granulomatous condition', 'palisade granulostermatitis', 'neutrophilic dermatosis', 'older individuals', 'perineoplastic process']",
"noisy_text": " Yeah, this would be more kind of the classic one, probably. What else? Here's the classic one clinically. What if there's small individual papules that have a central crust in them, often on apral skin? We have had several cases of the disseminated GA, but I'm not sure if they didn't have a crust. So, what's the type that had it? Perforating? Perforating GA. Perforating GA, good. So, this was granulomanuary. There's one other condition that gives you palisade granulostermatitis like this, but it also gives you some neutrophils infiltrate. That palisade and neutrophilic granulostermatitis, that's another thing that you at least have to think about when you see GA. If you see an older person that's got disseminated GA, think about it as a perineoplastic process. Sometimes you",
"corrected_text": " Yeah, this would be more kind of the classic one, probably. What else? Here's the classic one clinically. What if there's small individual papules that have a central crust in them, often on perioral skin? We have had several cases of the disseminated GA, but I'm not sure if they didn't have a crust. So, what's the type that had it? Perforating? Perforating GA. Perforating GA, good. So, this was granulomatous. There's one other condition that gives you palisade granulostermatitis like this, but it also gives you some neutrophils infiltrate. That palisade and neutrophilic dermatosis, that's another thing that you at least have to think about when you see GA. If you see an older person that's got disseminated GA, think about it as a perineoplastic process. Sometimes you",
"med_umls_ids": "[[{'entity': 'Clinical', 'concept_id': 'C0205210', 'confidence': 1.0}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'skin condition', 'concept_id': 'C1719933', 'confidence': 1.0}, {'entity': 'individual', 'concept_id': 'C0027361', 'confidence': 1.0}, {'entity': 'papules', 'concept_id': 'C0332563', 'confidence': 0.9999999403953552}, {'entity': 'central crust', 'concept_id': 'C0205204', 'confidence': 0.7633819580078125}, {'entity': 'perioral skin', 'concept_id': 'C0448802', 'confidence': 0.8075158596038818}], [{'entity': 'Perforating', 'concept_id': 'C0549099', 'confidence': 1.0}, {'entity': 'GA', 'concept_id': 'C0002915', 'confidence': 1.0}, {'entity': 'granulomatous condition', 'concept_id': 'C0439667', 'confidence': 0.8219265341758728}, {'entity': 'palisade', 'concept_id': 'C0331512', 'confidence': 0.8241410255432129}, {'entity': 'granulostermatitis', 'concept_id': 'C0743086', 'confidence': 0.7311265468597412}], [{'entity': 'Neutrophilic dermatosis', 'concept_id': 'C1142272', 'confidence': 1.0}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'GA', 'concept_id': 'C0002915', 'confidence': 1.0}], [{'entity': 'Disseminated', 'concept_id': 'C0205221', 'confidence': 1.0}, {'entity': 'GA', 'concept_id': 'C0002915', 'confidence': 1.0}, {'entity': 'older', 'concept_id': 'C0337524', 'confidence': 0.7771234512329102}, {'entity': 'individuals', 'concept_id': 'C0027361', 'confidence': 0.8766164779663086}, {'entity': 'perineoplastic process', 'concept_id': 'C0027671', 'confidence': 0.8771522045135498}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_786",
"caption_rating": "8"
},
{
"": "1007155",
"caption": "Chronic atrophic gastritis with intestinal metaplasia and muscularization of the lamina propria.",
"image_path": "r7OA0Trj5hQ_image_5c60bb1a-0cfa-4ae1-98cc-acbc869ca38e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Chronic atrophic gastritis', 'Intestinal metaplasia', 'Muscularization of the lamina propria', 'Muscularis propria acts like a barrier', 'High grade dysplasia', 'Malignant glands going into the muscle bundle', 'Chronic atrophic gastritis', 'Intestinal metaplasia', 'Muscularization of the lamina propria', 'Muscularis propria acts like a barrier', 'High grade dysplasia', 'Malignant glands going into the muscle bundle']",
"noisy_text": " So this is chronic atrophic gastritis with intestinal metaplasia with muscularization of the lamina propria. More than one pathology involved in this biopsy. Plastic changes seen above are known as TIS. Once they cross the muscular ischemicosa, then only they are eligible for T1. So muscular ischemicosa acts like a barrier. Here, in this picture, you can see the muscular ischemicosa acts like a barrier. So this is only high grade dysplasia. Whereas here, you can see the malignant glands going into the muscle bundle. And glands, malignant glands are seen on both sides of the muscle. So this",
"corrected_text": " So this is chronic atrophic gastritis with intestinal metaplasia with muscularization of the lamina propria. More than one pathology involved in this biopsy. Plastic changes seen above are known as TIS. Once they cross the muscularis propria, then only they are eligible for T1. So muscularis propria acts like a barrier. Here, in this picture, you can see the muscularis propria acts like a barrier. So this is only high grade dysplasia. Whereas here, you can see the malignant glands going into the muscle bundle. And glands, malignant glands are seen on both sides of the muscle. So this",
"med_umls_ids": "[[{'entity': 'Chronic atrophic gastritis', 'concept_id': 'C0017154', 'confidence': 1.0}, {'entity': 'intestinal metaplasia', 'concept_id': 'C0334037', 'confidence': 1.0}, {'entity': 'muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}], [{'entity': 'Plastic changes', 'concept_id': 'C0392747', 'confidence': 0.7598782777786255}, {'entity': 'TIS', 'concept_id': 'C0475413', 'confidence': 1.0}], [{'entity': 'Muscularis propria', 'concept_id': 'C0225358', 'confidence': 1.0}, {'entity': 'barrier', 'concept_id': 'C1706912', 'confidence': 1.0}], [{'entity': 'High grade', 'concept_id': 'C0205082', 'confidence': 1.0}, {'entity': 'malignant glands', 'concept_id': 'C0205282', 'confidence': 0.7218497395515442}, {'entity': 'muscle bundle', 'concept_id': 'C0504095', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_787",
"caption_rating": "10"
},
{
"": "1004401",
"caption": "Extravasated erythrocytes, siderophages, and an infiltrate of lymphocytes are seen at the periphery.",
"image_path": "8S4LeiO6Bbk_image_560fbaaf-db18-4369-bae1-323ae1e9c5c6.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['siderophages']",
"noisy_text": " by these dilated vascular channels. Let's look at the bottom piece, which frequently do contain these papillary projections, which protrude into the lumina, these plump endothelial cells, and then at the periphery, more compressed vascular channels, which dissect between collagen bundles. And it's at the periphery one frequently sees extravasated erythrocytes, siderophages, and an infiltrate of lymphocytes. So targetoid hemocidiotic hemangioma. Sometimes it can be quite difficult to distinguish these from patch gage stage Kaposi's. And again, HHV8 stain will help you because these are routinely negative for HHVA and the Kaposi's, of course, will always stain with an HHV8 stain. And we will close out our discussion with slide number 12, which is kind of a cool case to end on. And we have two pieces of tissue here. And if",
"corrected_text": " by these dilated vascular channels. Let's look at the bottom piece, which frequently do contain these papillary projections, which protrude into the lumina, these plump endothelial cells, and then at the periphery, more compressed vascular channels, which dissect between collagen bundles. And it's at the periphery one frequently sees extravasated erythrocytes, siderophages, and an infiltrate of lymphocytes. So targetoid hemosiderotic hemangioma. Sometimes it can be quite difficult to distinguish these from patch gage stage Kaposi's. And again, HHV8 stain will help you because these are routinely negative for HHVA and the Kaposi's, of course, will always stain with an HHV8 stain. And we will close out our discussion with slide number 12, which is kind of a cool case to end on. And we have two pieces of tissue here. And if",
"med_umls_ids": "[[{'entity': 'Dilated', 'concept_id': 'C0700124', 'confidence': 0.9999999403953552}, {'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}], [{'entity': 'Papillary projections', 'concept_id': 'C0016538', 'confidence': 0.7451471090316772}, {'entity': 'lumina', 'concept_id': 'C0524462', 'confidence': 0.845600426197052}], [{'entity': 'Enlarged endothelial cells', 'concept_id': 'C0423263', 'confidence': 0.7785332202911377}], [{'entity': 'Compressed vascular channels', 'concept_id': 'C1336948', 'confidence': 0.5993747711181641}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'bundles', 'concept_id': 'C3658308', 'confidence': 0.8706014752388}], [{'entity': 'Extravasated', 'concept_id': 'C0015376', 'confidence': 0.868863582611084}, {'entity': 'erythrocytes', 'concept_id': 'C0014772', 'confidence': 1.0}, {'entity': 'siderophages', 'concept_id': 'C1136253', 'confidence': 0.7251443266868591}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}], [{'entity': 'Targetoid hemosiderotic hemangioma', 'concept_id': 'C0346076', 'confidence': 0.9999999403953552}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'targetoid hemosiderotic hemangioma', 'concept_id': 'C0346076', 'confidence': 0.9999999403953552}, {'entity': \"patch stage Kaposi's\", 'concept_id': 'C0280201', 'confidence': 0.7629613280296326}], [{'entity': 'HHV8', 'concept_id': 'C0036220', 'confidence': 1.0}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_788",
"caption_rating": "10"
},
{
"": "1005737",
"caption": "The depth of the pulmonary involvement suggests a neoplastic process.",
"image_path": "udoW6VSqsm4_image_633b3717-379e-4f46-8628-b5393a9e3a00.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['atypical cells', 'pleomorphism', 'neoplastic process', 'inflammatory lymphocytic infiltrate', 'depth of pulmonary involvement']",
"noisy_text": " So I thought about a neoplastic process as opposed to just an inflammatory lymphocytic infiltrate. Yeah, like that cell is atypical and it's kind of large and bizarre in its morphology. And you look around and you say, yeah, there's some pre-morphism of some of these cells. That's not striking cytologic atypia like we see with somebody who might have a large sort of anoplastic lymphoma, but there's no question that a number of these cells are pretty atypical. So yeah, and another clue that you might be dealing with a neoplastic as opposed to the just an ion-reactive inflammatory process is the depth of the pulmonary, all the way to the fat. Usually if you're dealing",
"corrected_text": " So I thought about a neoplastic process as opposed to just an inflammatory lymphocytic infiltrate. Yeah, like that cell is atypical and it's kind of large and bizarre in its morphology. And you look around and you say, yeah, there's some pleomorphism of some of these cells. That's not striking cytologic atypia like we see with somebody who might have a large sort of anoplastic lymphoma, but there's no question that a number of these cells are pretty atypical. So yeah, and another clue that you might be dealing with a neoplastic as opposed to the just an reactive inflammatory process is the depth of the pulmonary, all the way to the fat. Usually if you're dealing",
"med_umls_ids": "[[{'entity': 'narrator', 'concept_id': 'C1135957', 'confidence': 0.7711340188980103}, {'entity': 'neoplastic process', 'concept_id': 'C0027671', 'confidence': 1.0}, {'entity': 'inflammatory lymphocytic infiltrate', 'concept_id': 'C2674297', 'confidence': 1.0}], [{'entity': 'atypical', 'concept_id': 'C0205182', 'confidence': 1.0}, {'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}, {'entity': 'pleomorphism', 'concept_id': 'C0032219', 'confidence': 1.0}, {'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'neoplasia', 'concept_id': 'C0027651', 'confidence': 1.0}], [{'entity': 'depth', 'concept_id': 'C0205125', 'confidence': 1.0}, {'entity': 'pulmonary', 'concept_id': 'C0024109', 'confidence': 0.9999999403953552}, {'entity': 'involvement', 'concept_id': 'C1314939', 'confidence': 1.0}, {'entity': 'neoplastic process', 'concept_id': 'C0027671', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_789",
"caption_rating": "8"
},
{
"": "1007706",
"caption": "The sample is stratified and shows cribriform and micropapillary process.",
"image_path": "r7OA0Trj5hQ_image_14db8a12-3821-44b4-9c8e-6a119b6dc825.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['nuclei touching the top of the apical membrane', 'prominent nuclei', 'loss of cellular polarity', 'cribriform', 'micropapillary process', 'nuclei touching the top of the apical membrane', 'prominent nuclei', 'loss of cellular polarity', 'cribriform', 'micropapillary process', 'nuclei touching the top of the apical membrane', 'prominent nuclei', 'loss of cellular polarity', 'cribriform', 'micropapillary process']",
"noisy_text": " Can you all see the nuclei touching the top of the apical membrane? And see the prominent nuclei. And see the nuclei are running in different directions. This nuclei is running in this direction, whereas this nuclei is running in this direction. This nuclei is running in this direction. So there is loss of polarity. Okay, so here also it is stratified, reaching up to the top, and it is showing loss of polarity. And see the cribriformic. And this is a micropapillary process. Since it's a high power, you are not able to appreciate it better. I will show it to you in the other pictures. But here",
"corrected_text": " Can you all see the nuclei touching the top of the apical membrane? And see the prominent nuclei. And see the nuclei are running in different directions. This nuclei is running in this direction, whereas this nuclei is running in this direction. This nuclei is running in this direction. So there is loss of cellular polarity. Okay, so here also it is stratified, reaching up to the top, and it is showing loss of cellular polarity. And see the cribriform. And this is a micropapillary process. Since it's a high power, you are not able to appreciate it better. I will show it to you in the other pictures. But here",
"med_umls_ids": "[[{'entity': 'Loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'cellular polarity', 'concept_id': 'C0085304', 'confidence': 1.0}, {'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}], [{'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'stratified', 'concept_id': 'C0205363', 'confidence': 1.0}, {'entity': 'cribriform', 'concept_id': 'C1621425', 'confidence': 0.9999999403953552}, {'entity': 'micropapillary process', 'concept_id': 'C1290608', 'confidence': 0.763504683971405}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_790",
"caption_rating": "8"
},
{
"": "1004988",
"caption": "Lamina propria is full of cells with a distinct cell border, abundant foamy cytoplasm, and centrally placed nucleus in gastric xanthoma.",
"image_path": "r7OA0Trj5hQ_image_23c31f4f-613e-4a94-8a05-211bd141909a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['young males', 'inflammatory bowel disease', 'lamina propria', 'distinct cell border', 'foamy cytoplasm', 'centrally placed nucleus', 'gastric xanthoma', 'young males', 'inflammatory bowel disease', 'lamina propria', 'distinct cell border', 'foamy cytoplasm', 'centrally placed nucleus', 'gastric xanthoma', 'young males', 'inflammatory bowel disease', 'lamina propria', 'distinct cell border', 'foamy cytoplasm', 'centrally placed nucleus', 'gastric xanthoma']",
"noisy_text": " It is commonly seen in young males, and they present with the signs and symptoms of inflammatory bowel disease. Interesting condition. Here, the lamina propria is full of cells with a distinct cell border, abundant foamy cytoplasm, most of the time centrally placed nucleus. Sometimes it is pushed to the periphery. The central nuclear placement is very important for a diagnosis of xanthoma. For a signet cells, it will be predominantly peripherally pushed nucleus. And when you have doubt, you do a CD68, which will be strongly positive. And so this is a gastric xanthoma. Here, it",
"corrected_text": " It is commonly seen in young males, and they present with the signs and symptoms of inflammatory bowel disease. Interesting condition. Here, the lamina propria is full of cells with a distinct cell border, abundant foamy cytoplasm, most of the time centrally placed nucleus. Sometimes it is pushed to the periphery. The central nuclear placement is very important for a diagnosis of xanthoma. For a signet ring cells, it will be predominantly peripherally pushed nucleus. And when you have doubt, you do a CD68, which will be strongly positive. And so this is a gastric xanthoma. Here, it",
"med_umls_ids": "[[{'entity': 'Xanthoma', 'concept_id': 'C0302314', 'confidence': 1.0}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'young', 'concept_id': 'C0332239', 'confidence': 1.0}, {'entity': 'males', 'concept_id': 'C0086582', 'confidence': 1.0}, {'entity': 'signs', 'concept_id': 'C0220912', 'confidence': 0.9999999403953552}, {'entity': 'symptoms', 'concept_id': 'C0683368', 'confidence': 1.0}, {'entity': 'inflammatory bowel disease', 'concept_id': 'C0021390', 'confidence': 1.0}], [{'entity': 'Lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'cell border', 'concept_id': 'C0205284', 'confidence': 0.773768424987793}, {'entity': 'foamy cytoplasm', 'concept_id': 'C0010834', 'confidence': 0.7207725048065186}, {'entity': 'centrally', 'concept_id': 'C0205099', 'confidence': 0.7070305943489075}, {'entity': 'nucleus', 'concept_id': 'C0007610', 'confidence': 1.0}, {'entity': 'gastric xanthoma', 'concept_id': 'C1282522', 'confidence': 1.0}], [{'entity': 'CD68', 'concept_id': 'C0108799', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'xanthoma', 'concept_id': 'C0302314', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_791",
"caption_rating": "9"
},
{
"": "1004617",
"caption": "The narrator describes a miniaturized hair follicle with a stem cell area known as the mantle zone.",
"image_path": "LlPaENuqzVQ_image_a9bad7d7-e820-43ea-879e-fb44eed5e7d3.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['miniaturized hair follicle', 'mantle zone', 'stem cell area', 'bulge', 'apocrine gland', 'sebaceous gland', 'hamartoma', 'fibrous sheath', 'bulge']",
"noisy_text": " Like, it looks more like if there's, if I'm going to guess, like there's, I feel like there's a little bit of like, I would guess more like towards the, like a glandular. Yeah, well, it's, it's, it's a little miniaturized hair follicle. Nope. It's like this little guy here. It's like a little tiny follicle. And there's, we always think of three parts of the hair follicle. We think of the infundibulum, the isthmus, and we think of the inferior portion, but there's a very important part right around the isthmic part, just beneath the follicle, the infundibulum, and then where the inferior portion begins, that's known as the mantle zone. And that's kind of where all the action is. That's really kind of a stem cell area that sometimes those cells will form a little bulge there and they actually will end up forming an apocrine gland. Sometimes they'll end up forming a sebaceous gland. Sometimes they, you know, will just, they'll form, sometimes they form a little hammertoma, like you see right here. And they actually end up getting you this little sort of primitive little, it almost looks like a mini hair follicle that didn't really form. And then when you look at a hair follicle, it's comprised not only of the epithelial component, but there's also a periepithelial sheath around it, a fibrous sheath around the hair follicle. And so this is a hammertoma that involves both of those. So it's got a fibrous element to it. And then",
"corrected_text": " Like, it looks more like if there's, if I'm going to guess, like there's, I feel like there's a little bit of like, I would guess more like towards the, like a glandular. Yeah, well, it's, it's, it's a little miniaturized hair follicle. Nope. It's like this little guy here. It's like a little tiny follicle. And there's, we always think of three parts of the hair follicle. We think of the infundibulum, the isthmus, and we think of the inferior portion, but there's a very important part right around the isthmic part, just beneath the follicle, the infundibulum, and then where the inferior portion begins, that's known as the mantle zone. And that's kind of where all the action is. That's really kind of a stem cell area that sometimes those cells wiform a little bulge there and they actually wiend up forming an apocrine gland. Sometimes they'end up forming a sebaceous gland. Sometimes they, you know, will just, they'form, sometimes they form a little hamartoma, like you see right here. And they actually end up getting you this little sort of primitive little, it almost looks like a mini hair follicle that didn't really form. And then when you look at a hair follicle, it's comprised not only of the epithelial component, but there's also a periepithelial sheath around it, a fibrous sheath around the hair follicle. And so this is a hamartoma that involves both of those. So it's got a fibrous element to it. And then",
"med_umls_ids": "[[{'entity': 'narrator', 'concept_id': 'C1135957', 'confidence': 0.7711340188980103}, {'entity': 'miniaturized', 'concept_id': 'C0872350', 'confidence': 0.8111259341239929}, {'entity': 'hair follicle', 'concept_id': 'C0221971', 'confidence': 1.0}, {'entity': 'stem cell', 'concept_id': 'C0038250', 'confidence': 1.0}, {'entity': 'mantle zone', 'concept_id': 'C1512987', 'confidence': 1.0}], [{'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'mantle', 'concept_id': 'C0232445', 'confidence': 0.8497024178504944}, {'entity': 'zone', 'concept_id': 'C1710706', 'confidence': 1.0}, {'entity': 'bulge', 'concept_id': 'C0038999', 'confidence': 0.9999999403953552}, {'entity': 'apocrine gland', 'concept_id': 'C0003584', 'confidence': 0.9999998807907104}, {'entity': 'sebaceous gland', 'concept_id': 'C0036505', 'confidence': 1.0}, {'entity': 'hamartoma', 'concept_id': 'C0018552', 'confidence': 0.9999999403953552}], [{'entity': 'hamartoma', 'concept_id': 'C0018552', 'confidence': 0.9999999403953552}, {'entity': 'epithelial component', 'concept_id': 'C1707933', 'confidence': 0.8783122897148132}, {'entity': 'fibrous sheath', 'concept_id': 'C1185724', 'confidence': 1.0}, {'entity': 'hair follicle', 'concept_id': 'C0221971', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_792",
"caption_rating": "8"
},
{
"": "1004186",
"caption": "Presence of luminal ruffling in prostate glands is a reassuring sign as prostate cancer usually has sharp luminal borders.",
"image_path": "iklRyY1nBIE_image_47426b94-b186-490d-8be9-bbb9dce1866f.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['luminal ruffling', 'prostate glands', 'early corpora and mucin formation', 'atrophic gland', 'luminal ruffling', 'prostate glands', 'early corpora and mucin formation', 'atrophic gland']",
"noisy_text": " And if you go a bit closer, you can see that they have a little bit of luminal ruffling. When you see luminal ruffling, that should make you feel a little bit more comfortable, because prostate cancer usually has sharp luminal borders. The problem is the previous case I showed you actually had sharp luminal borders, even though it was partial atrophy. So that's what makes this tricky. But in this case, you can see the fairly well circumscribed, one of the glands even has a little bit of early corpora and malatial formation. But you also have this gland over here that looks somewhat similar, but a little bit more atrophic. And if you look at the corresponding immunosuchemical stain and that focus of interest, we'll see what happens. So again, this",
"corrected_text": " And if you go a bit closer, you can see that they have a little bit of luminal ruffling. When you see luminal ruffling, that should make you feel a little bit more comfortable, because prostate cancer usually has sharp luminal borders. The problem is the previous case I showed you actually had sharp luminal borders, even though it was partial atrophy. So that's what makes this tricky. But in this case, you can see the fairly well circumscribed, one of the glands even has a little bit of early corpora and mucin formation. But you also have this gland over here that looks somewhat similar, but a little bit more atrophic. And if you look at the corresponding immunohistochemical stain and that focus of interest, we'll see what happens. So again, this",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'luminal ruffling', 'concept_id': 'C3269125', 'confidence': 0.690064549446106}, {'entity': 'prostate glands', 'concept_id': 'C0033572', 'confidence': 0.8152219653129578}, {'entity': 'prostate cancer', 'concept_id': 'C0376358', 'confidence': 1.0}, {'entity': 'luminal borders', 'concept_id': 'C0524462', 'confidence': 0.6706532835960388}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_793",
"caption_rating": "8"
},
{
"": "1006972",
"caption": "DFSP is usually in the skin and rarely involves deep soft tissue.",
"image_path": "QDb68_G1HR4_image_5034c21b-cf71-4dc4-a11f-7800619e493a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['whirling pattern']",
"noisy_text": " This one's not really showing that but some of them do, they have a lot of whirling pattern. So the two other things that keep in the differential here are perineurioma and also dermatofibrosarcoma protuberans, DFSP, which also has a tends to have a story form or whirled and swirled growth pattern and also has a translocation sarcoma, has very bland spindle cells. Okay, I guess I don't have any immunostains with me to show you today but just briefly the immunostains, most of the immunostains that we use for soft tissue tumors are negative most of the time in low-grade fibromyxoid sarcoma. CD34 is usually negative which is a pretty easy way to separate this from DFSP. The other thing is that low-grade fibromyxoid sarcoma usually is a relatively larger and deep, deep soft tissue below the fascia mass, although there are rare examples that are small and superficial and those seem to be more common in children. But DFSP is essentially always in the skin, the dermis or subcutaneous and rarely ever involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is",
"corrected_text": " This one's not really showing that but some of them do, they have a lot of whirling pattern. So the two other things that keep in the differential here are perineurioma and also dermatofibrosarcoma protuberans, DFSP, which also has a tends to have a story form or whirled and swirled growth pattern and also has a translocation sarcoma, has very bland spindle cells. Okay, I guess I don't have any immunostaining with me to show you today but just briefly the immunostaining, most of the immunostaining that we use for soft tissue tumors are negative most of the time in low-grade fibromyxoid sarcoma. CD34 is usually negative which is a pretty easy way to separate this from DFSP. The other thing is that low-grade fibromyxoid sarcoma usually is a relatively larger and deep, deep soft tissue below the fascia mass, although there are rare examples that are small and superficial and those seem to be more common in children. But DFSP is essentially always in the skin, the dermis or subcutaneous and rarely ever involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is",
"med_umls_ids": "[[{'entity': 'Whirling pattern', 'concept_id': 'C0449774', 'confidence': 0.6110570430755615}, {'entity': 'perineurioma', 'concept_id': 'C0751691', 'confidence': 0.9999999403953552}, {'entity': 'dermatofibrosarcoma protuberans', 'concept_id': 'C0206647', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}], [{'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}, {'entity': 'skin', 'concept_id': 'C0444099', 'confidence': 1.0}, {'entity': 'deep soft tissue', 'concept_id': 'C0225317', 'confidence': 0.7996832728385925}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_794",
"caption_rating": "7"
},
{
"": "1008559",
"caption": "Loss of mucin and cellular polarity.",
"image_path": "r7OA0Trj5hQ_image_c3ffa8b2-387b-4d35-b219-84a9f742c5d7.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Loss of mucin', 'Loss of cellular polarity', 'Nuclear stratification', 'Mitosis', 'Apoptosis', 'Loss of mucin', 'Loss of cellular polarity', 'Nuclear stratification', 'Mitosis', 'Apoptosis']",
"noisy_text": " This is proliferative. With ATP or without ATP? With ATP? With invasion or without invasion? In this field, we cannot judge the invasion. So this is a proliferation with ATP. And see the glands stratify. And loss of mucin or less of mucin. And there is loss of polarity. Look at this nuclei running like in this direction. Look at this nuclei running in this direction. So clearly, loss of polarity. And the nuclear stratification is reaching the top of the epithelium, marked apoptosis. It's too thick to see the mitosis, but here you can see the mitosis. So this is stratification, loss of mucin, mitosis, apoptosis. So this",
"corrected_text": " This is proliferative. With ATP or without ATP? With ATP? With invasion or without invasion? In this field, we cannot judge the invasion. So this is a proliferation with ATP. And see the glands stratify. And loss of mucin or less of mucin. And there is loss of polarity. Look at this nuclei running like in this direction. Look at this nuclei running in this direction. So clearly, loss of polarity. And the nuclear stratification is reaching the top of the epithelium, marked apoptosis. It's too thick to see the mitosis, but here you can see the mitosis. So this is stratification, loss of mucin, mitosis, apoptosis. So this",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'proliferative cells', 'concept_id': 'C0334094', 'confidence': 0.8005025386810303}, {'entity': 'ATP', 'concept_id': 'C0001480', 'confidence': 1.0}, {'entity': 'hyperplastic glands', 'concept_id': 'C0020507', 'confidence': 0.7789753675460815}], [{'entity': 'Loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'mucin', 'concept_id': 'C0026682', 'confidence': 1.0}, {'entity': 'cellular polarity', 'concept_id': 'C0085304', 'confidence': 1.0}], [{'entity': 'Nuclear', 'concept_id': 'C0521447', 'confidence': 1.0}, {'entity': 'stratification', 'concept_id': 'C1514983', 'confidence': 1.0}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'apoptosis', 'concept_id': 'C0162638', 'confidence': 1.0}], [{'entity': 'Mitosis', 'concept_id': 'C0026255', 'confidence': 0.9999998807907104}, {'entity': 'stratification', 'concept_id': 'C1514983', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_795",
"caption_rating": "8"
},
{
"": "1004437",
"caption": "The lesion likely started as a benign leiomyoma.",
"image_path": "LlPaENuqzVQ_image_0827e0c8-1f0d-4227-b777-830b8dac8a2d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " and then it becomes much more aggressive. So that's why I'm going to do them with soft tissue. You have to think more of geography. You have to say, we're going to look at this entire thing and we're going to take sections from the whole thing because we want to make sure there's not zones in which it's become more cancerous, more aggressive in those areas. So this lesion probably started off as a benign lyomyoma. So I think in some areas it doesn't look very atypical. Right there, that's pretty typical appearing lyomyoma. Other areas though, you see there's zones of pleomorphism and some spindle-shaped cells that are quite very",
"corrected_text": " and then it becomes much more aggressive. So that's why I'm going to do them with soft tissue. You have to think more of geography. You have to say, we're going to look at this entire thing and we're going to take sections from the whole thing because we want to make sure there's not zones in which it's become more cancerous, more aggressive in those areas. So this lesion probably started off as a benign leiomyoma. So I think in some areas it doesn't look very atypical. Right there, that's pretty typical appearing lyomyoma. Other areas though, you see there's zones of pleomorphism and some spindle cells that are quite very",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'aggressive', 'concept_id': 'C0001807', 'confidence': 1.0}, {'entity': 'soft tissue', 'concept_id': 'C0225317', 'confidence': 0.9999999403953552}], [{'entity': 'Sections', 'concept_id': 'C0007876', 'confidence': 0.8770228624343872}, {'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'zones', 'concept_id': 'C1710706', 'confidence': 0.8182461857795715}, {'entity': 'cancerous', 'concept_id': 'C1514391', 'confidence': 0.763753354549408}, {'entity': 'aggressive', 'concept_id': 'C0001807', 'confidence': 1.0}], [{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'benign leiomyoma', 'concept_id': 'C0023267', 'confidence': 0.9082092046737671}], [{'entity': 'zones', 'concept_id': 'C1710706', 'confidence': 0.8182461857795715}, {'entity': 'pleomorphism', 'concept_id': 'C0032219', 'confidence': 1.0}, {'entity': 'spindle cells', 'concept_id': 'C0682540', 'confidence': 1.0}, {'entity': 'areas', 'concept_id': 'C0205146', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_796",
"caption_rating": "7"
},
{
"": "1005330",
"caption": "Fairly well circumscribed lesion with no increased mitotic activity.",
"image_path": "iklRyY1nBIE_image_881f5e73-0dd4-4feb-a638-26240b0dc364.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['basal cell hyperplasia', 'KI67 expression']",
"noisy_text": " fairly well circumscribed, no increased mitotic activity. Because one of the things you can do to distinguish if you're not sure is a KI67. KI67 will be very low in basal cell hyperplasia. Even fluorid basal cell hyperplasia should not have a very high KI67 expression. In contrast, basal cell carcinoma, as no surprise, is actually with a high KI67 level. So that's something else. In cases in which one is struggling, that's something that may be helpful. Let me see. Yeah, this is just another example of basal cell hyperplasia. This is in a Terp specimen. So it's not uncommon to",
"corrected_text": " fairly well circumscribed, no increased mitotic activity. Because one of the things you can do to distinguish if you're not sure is a KI67. KI67 will be very low in basal cell hyperplasia. Even fluorid basal cell hyperplasia should not have a very high KI67 expression. In contrast, basal cell carcinoma, as no surprise, is actually with a high KI67 level. So that's something else. In cases in which one is struggling, that's something that may be helpful. Let me see. Yeah, this is just another example of basal cell hyperplasia. This is in a Terp specimen. So it's not uncommon to",
"med_umls_ids": "[[{'entity': 'Fairly', 'concept_id': 'C4086298', 'confidence': 0.9045276641845703}, {'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'mitotic activity', 'concept_id': 'C1334779', 'confidence': 1.0}], [{'entity': 'KI67', 'concept_id': 'C1334508', 'confidence': 1.0}, {'entity': 'basal cell', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'basal cell carcinoma', 'concept_id': 'C0007117', 'confidence': 1.0}], [{'entity': 'Basal cell hyperplasia', 'concept_id': 'C0333990', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_797",
"caption_rating": "8"
},
{
"": "1009072",
"caption": "The pain cocktail stain is negative in the epithelial component.",
"image_path": "iklRyY1nBIE_image_c49b67e3-332c-4010-98ee-fa3925d7a0cc.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['Wild tumor with bad nuclei', 'Mitotic activity', 'Epithelial and spindle cell component', 'Pain cocktail stain']",
"noisy_text": " We need to exclude these two. And I'll just let you all take a look at this and try and figure out what's going on. So this looks like another wild tumor of bad nuclei. If you look carefully, you can see some mitotic activity there. This looks like it has both an epithelial and a stromal component to it, or at least an epithelial and a spindle cell component to it. The epithelial component looks concerning. And if I show you the corresponding stain, that will give it away. This will give the diagnosis away. So this is the pain cocktail. And as you can see, it's negative in the epithelial component for basal cells.",
"corrected_text": " We need to exclude these two. And I'll just let you all take a look at this and try and figure out what's going on. So this looks like another wild tumor of bad nuclei. If you look carefully, you can see some mitotic activity there. This looks like it has both an epithelial and spindle cell component to it, or at least an epithelial and a spindle cell component to it. The epithelial component looks concerning. And if I show you the corresponding stain, that will give it away. This will give the diagnosis away. So this is the pain cocktail. And as you can see, it's negative in the epithelial component for basal cells.",
"med_umls_ids": "[[{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'epithelial', 'concept_id': 'C0221908', 'confidence': 1.0}, {'entity': 'spindle cell', 'concept_id': 'C0682540', 'confidence': 0.9999999403953552}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'epithelial component', 'concept_id': 'C1707933', 'confidence': 0.8783122897148132}], [{'entity': 'Mitotic activity', 'concept_id': 'C1334779', 'confidence': 1.0}], [{'entity': 'pain cocktail', 'concept_id': 'C0678420', 'confidence': 0.9142165184020996}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'epithelial component', 'concept_id': 'C1707933', 'confidence': 0.8783122897148132}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_798",
"caption_rating": "8"
},
{
"": "1006192",
"caption": "Chronicity can cause architectural distortion in addition to nonspecific findings.",
"image_path": "sDFjOtMAYrk_image_eaef126a-2187-4240-8b4e-889be1f0fb4f.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "[]",
"noisy_text": " cytosis that includes some eosinophils. So, the other trich I like to use, and I heard this from Dr. Appelman one time when he was lecturing, and he described crypt architecture in cases with inflammatory bowel disease, you no longer have that nice organized test tubes in a rack kind of architecture. The glands start to look like anything they want to look like. Rabbits, monkeys, the face of Jesus, whatever, except for test tubes on a rack. And the other thing is, sometimes you'll see them instead of growing down, they'll grow sideways. So, that's very apparent, very abnormal. So, I would say this is great evidence of chronicity, good architectural distortion. What other features besides architecture can you see in cases where there's some chronicity, albeit nonspecific findings? I mean, nothing is specific in chronic inflammatory colonic pathology,",
"corrected_text": " cytosis that includes some eosinophils. So, the other trich I like to use, and I heard this from Dr. Appelman one time when he was lecturing, and he described crypt architecture in cases with inflammatory bowel disease, you no longer have that nice organized tubular architecture. The glands start to look like anything they want to look like. Rabbits, monkeys, the face of Jesus, whatever, except for test tubes on a rack. And the other thing is, sometimes you'll see them instead of growing down, they'll grow sideways. So, that's very apparent, very abnormal. So, I would say this is great evidence of chronicity, good architectural distortion. What other features besides architecture can you see in cases where there's some chronicity, albeit nonspecific findings? I mean, nothing is specific in chronic inflammatory colonic pathology,",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'cytosis', 'concept_id': 'C0010843', 'confidence': 0.7890887260437012}], [{'entity': 'Inflammatory bowel disease', 'concept_id': 'C0021390', 'confidence': 1.0}, {'entity': 'loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'tubular', 'concept_id': 'C0151747', 'confidence': 1.0}, {'entity': 'architecture', 'concept_id': 'C0003737', 'confidence': 1.0}, {'entity': 'abnormal', 'concept_id': 'C0205161', 'confidence': 1.0}, {'entity': 'growth', 'concept_id': 'C0018270', 'confidence': 1.0}], [{'entity': 'Chronicity', 'concept_id': 'C0547045', 'confidence': 1.0}, {'entity': 'architectural distortion', 'concept_id': 'C2826609', 'confidence': 1.0}, {'entity': 'nonspecific', 'concept_id': 'C0750540', 'confidence': 1.0}, {'entity': 'findings', 'concept_id': 'C2607943', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_799",
"caption_rating": "8"
},
{
"": "1008502",
"caption": "Low-grade fibromyxoid sarcoma is defined by a translocation, with the most common being the translocation 716 between the FUS and CREB3L2 genes.",
"image_path": "QDb68_G1HR4_image_152660c1-7a02-4527-a98a-a5561a3fa697.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['synovial sarcoma', 'low-grade fibromyxoid sarcoma', 'FUS gene rearrangement']",
"noisy_text": " but I've seen very rare examples where there were very well differentiated areas in a synovial sarcoma that kind of had a fibrous look and looked similar to low-grade fibromyxoid sarcoma. So in that case, obviously you could use other stains like keratins and if you like TLE1 you could do that. And then in the end, if you have trouble, molecular pathology can help us out. Like I said earlier, these tumors, low-grade fibromyxoid sarcoma is defined by a translocation. The most common translocation is the translocation 716 which is between the genes FUS and CREB3L2. And there's also a small subset of these that have an alternate translocation which is between the FUS gene and the CREB3L1 gene. So FUS-CREB3L2 or FUS-CREB3L1 gene fusion can support the diagnosis. So you could use break apart fish for FUS. If the tumor looks like this and FUS is positive for FUS rearrangement, then you should be pretty good in calling it a low-grade fibromyxoid sarcoma. But do be aware that there are many other tumors in soft tissue pathology that have FUS rearrangements, myxoid liposarcoma and others. They usually have a different histologic appearance. So that's why you can never use, at least in my opinion, you shouldn't use molecular pathology by itself. You have to couple it with the clinical scenario and the histologic features and the immunostain findings. Put",
"corrected_text": " but I've seen very rare examples where there were very well differentiated areas in a synovial sarcoma that kind of had a fibrous look and looked similar to low-grade fibromyxoid sarcoma. So in that case, obviously you could use other stains like keratins and if you like TLE1 you could do that. And then in the end, if you have trouble, molecular pathology can help us out. Like I said earlier, these tumors, low-grade fibromyxoid sarcoma is defined by a translocation. The most common translocation is the translocation 716 which is between the genes FUS and CREB3L2. And there's also a small subset of these that have an alternate translocation which is between the FUS gene and the CREB3L1 gene. So FUS-CREB3L2 or FUS-CREB3L1 gene fusion can support the diagnosis. So you could use break apart fish for FUS. If the tumor looks like this and FUS is positive for FUS gene rearrangement, then you should be pretty good in calling it a low-grade fibromyxoid sarcoma. But do be aware that there are many other tumors in soft tissue pathology that have FUS gene rearrangements, myxoid liposarcoma and others. They usually have a different histologic appearance. So that's why you can never use, at least in my opinion, you shouldn't use molecular pathology by itself. You have to couple it with the clinical scenario and the histologic features and the immunohistochemistry findings. Put",
"med_umls_ids": "[[{'entity': 'Synovial sarcoma', 'concept_id': 'C0039101', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}], [{'entity': 'Keratin', 'concept_id': 'C0010803', 'confidence': 1.0}, {'entity': 'TLE1', 'concept_id': 'C1420752', 'confidence': 1.0}, {'entity': 'stains', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'differentiate', 'concept_id': 'C0205615', 'confidence': 0.9999998807907104}, {'entity': 'synovial sarcoma', 'concept_id': 'C0039101', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}], [{'entity': 'Low-grade fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.9999998807907104}, {'entity': 'translocation', 'concept_id': 'C0040715', 'confidence': 1.0}, {'entity': 'translocation', 'concept_id': 'C0040715', 'confidence': 1.0}, {'entity': 'FUS', 'concept_id': 'C0268696', 'confidence': 1.0}, {'entity': 'CREB3L2', 'concept_id': 'C1428221', 'confidence': 0.9999998807907104}, {'entity': 'genes', 'concept_id': 'C0017337', 'confidence': 1.0}], [{'entity': 'Break apart FISH', 'concept_id': 'C3831569', 'confidence': 0.7467014789581299}, {'entity': 'FUS', 'concept_id': 'C0268696', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}], [{'entity': 'Molecular pathology', 'concept_id': 'C0596962', 'confidence': 1.0}, {'entity': 'coupled', 'concept_id': 'C1948027', 'confidence': 1.0}, {'entity': 'clinical scenario', 'concept_id': 'C0205210', 'confidence': 0.6381967067718506}, {'entity': 'histologic features', 'concept_id': 'C1301121', 'confidence': 0.816085159778595}, {'entity': 'immunohistochemistry', 'concept_id': 'C0021044', 'confidence': 0.9999998807907104}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_800",
"caption_rating": "9"
},
{
"": "1007767",
"caption": "Clodin-1 is often expressed in perineuriomas, which can be a pitfall in diagnosis as it may resemble low-grade fibromyxoid sarcoma. Glut-1 is usually negative in perineuriomas but may be positive in rare cases of low-grade fibromyxoid sarcoma. MUC4 is a sensitive and specific marker for low-grade fibromyxoid sarcoma and should be negative in perineuriomas and DFSP.",
"image_path": "QDb68_G1HR4_image_3e6de5d1-a982-4101-a41c-00b1deecdf6c.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The one stain that was described a few years ago as being helpful here is called MUC4, M-U-C-4. MUC4 is in the setting of a fibroblastic spindle cell tumor like this, it is a very sensitive and specific marker at least as of today's date in 2018, so far it tends to be very sensitive and specific marker for low-grade fibromyxoid sarcoma and it should be negative in perineuriomas and DFSP and other entities in the differential diagnosis. Now I'm",
"corrected_text": " They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The one stain that was described a few years ago as being helpful here is called MUC4, M-U-C-4. MUC4 is in the setting of a fibroblastic spindle cell tumor like this, it is a very sensitive and specific marker at least as of today's date in 2018, so far it tends to be very sensitive and specific marker for low-grade fibromyxoid sarcoma and it should be negative in perineuriomas and DFSP and other entities in the differential diagnosis. Now I'm",
"med_umls_ids": "[[{'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}, {'entity': 'expressed', 'concept_id': 'C0017262', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'rare', 'concept_id': 'C0521114', 'confidence': 1.0}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'MUC4', 'concept_id': 'C1417496', 'confidence': 0.9999999403953552}, {'entity': 'sensitive', 'concept_id': 'C0020517', 'confidence': 1.0}, {'entity': 'marker', 'concept_id': 'C0005516', 'confidence': 0.9999999403953552}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_801",
"caption_rating": "9"
},
{
"": "1008018",
"caption": "Histopathology shows predominantly pink fibrous component and a lesser bluish myxoid component, consistent with fibromyxoid tumors.",
"image_path": "QDb68_G1HR4_image_0ef4ee74-1969-4d6a-8141-931c1ed6375d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Predominantly pink fibrous component and a lesser myxoid bluish component.', 'Predominantly pink fibrous component and a lesser myxoid bluish component.']",
"noisy_text": " background fades out kind of quickly on H and E but the predominant color here is pink and I think this is one easy way to help remember this, fibromyxoid. The name says fibro before the word myxo. So the fibro is the pink part, the myxoid is the bluish pale part and these tumors usually not always but usually have a predominantly fibrous pink component and a lesser myxoid bluish component so it looks more pink. The way I also remember it is some of the original tumors that Dr. Evans described were misdiagnosed originally as either fibroma which is a good example of why it's dangerous to call",
"corrected_text": " background fades out kind of quickly on H and E but the predominant color here is pink and I think this is one easy way to help remember this, fibromyxoid. The name says fibro before the word myxoid. So the fibro is the pink part, the myxoid is the bluish pale part and these tumors usually not always but usually have a predominantly fibrous pink component and a lesser myxoid bluish component so it looks more pink. The way I also remember it is some of the original tumors that Dr. Evans described were misdiagnosed originally as either fibroma which is a good example of why it's dangerous to call",
"med_umls_ids": "[[{'entity': 'Histopathology', 'concept_id': 'C0243140', 'confidence': 1.0}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}, {'entity': 'consistent with', 'concept_id': 'C0332290', 'confidence': 1.0}, {'entity': 'fibromyxoid tumors', 'concept_id': 'C0205766', 'confidence': 0.9253939986228943}], [{'entity': 'Fibro', 'concept_id': 'C0016053', 'confidence': 0.9999999403953552}, {'entity': 'pink', 'concept_id': 'C0332585', 'confidence': 1.0}, {'entity': 'myxoid', 'concept_id': 'C0205295', 'confidence': 1.0}, {'entity': 'bluish pale part', 'concept_id': 'C0392768', 'confidence': 0.6970505118370056}], [{'entity': 'original', 'concept_id': 'C0205313', 'confidence': 1.0}, {'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'misdiagnosed', 'concept_id': 'C0679838', 'confidence': 0.896425724029541}, {'entity': 'fibroma', 'concept_id': 'C0016045', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_802",
"caption_rating": "9"
},
{
"": "1007304",
"caption": "Thick vessel wall with narrowed lumen seen in high power.",
"image_path": "r7OA0Trj5hQ_image_13da7322-e4b8-4a3d-8db9-cba386461840.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " In high power, you can see very thick vessel wall with the narrowing of the lumen, whereas here, it is relatively preserved. So you want to know whether it is a vein or artery. Please believe me, this is a vein, and this is an artery. And that is proved by the elastic tissue strain. These are all pictures from Dr. Gonzalez's Twitter. And you can see here, there is no internal elastic lamina, whereas here, there is an internal elastic lamina. So this is a branch of mesenteric artery, whereas this is a branch of mesenteric vein. And there is a condition called as idiopathic myointimal hyperplasia of the mesenteric vein. I don't know how many of you have heard this company. There's a",
"corrected_text": " In high power, you can see very thick vessel wall with the narrowing of the lumen, whereas here, it is relatively preserved. So you want to know whether it is a vein or artery. Please believe me, this is a vein, and this is an artery. And that is proved by the elastic tissue strain. These are all pictures from Dr. Gonzalez's Twitter. And you can see here, there is no internal elastic lamina, whereas here, there is an internal elastic lamina. So this is a branch of mesenteric artery, whereas this is a branch of mesenteric vein. And there is a condition called as idiopathic myointimal hyperplasia of mesenteric vein of the mesenteric vein. I don't know how many of you have heard this company. There's a",
"med_umls_ids": "[[{'entity': 'Thick vessel wall', 'concept_id': 'C1180033', 'confidence': 0.6420797109603882}, {'entity': 'lumen', 'concept_id': 'C0524461', 'confidence': 0.9999998807907104}, {'entity': 'power', 'concept_id': 'C0032863', 'confidence': 1.0}], [{'entity': 'Identification', 'concept_id': 'C0020792', 'confidence': 1.0}, {'entity': 'vein', 'concept_id': 'C0042449', 'confidence': 1.0}, {'entity': 'artery', 'concept_id': 'C0003842', 'confidence': 1.0}, {'entity': 'elastic tissue', 'concept_id': 'C0013762', 'confidence': 1.0}, {'entity': 'strain', 'concept_id': 'C0080194', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'internal elastic lamina', 'concept_id': 'C1180561', 'confidence': 1.0}, {'entity': 'artery', 'concept_id': 'C0003842', 'confidence': 1.0}, {'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'vein', 'concept_id': 'C0042449', 'confidence': 1.0}], [{'entity': 'Branches', 'concept_id': 'C1182977', 'confidence': 0.7288598418235779}, {'entity': 'mesenteric artery', 'concept_id': 'C0025465', 'confidence': 1.0}, {'entity': 'vein', 'concept_id': 'C0042449', 'confidence': 1.0}, {'entity': 'examples', 'concept_id': 'C1707959', 'confidence': 0.8639216423034668}], [{'entity': 'Idiopathic myointimal hyperplasia', 'concept_id': 'C0333978', 'confidence': 0.8139097094535828}, {'entity': 'mesenteric vein', 'concept_id': 'C0025473', 'confidence': 1.0}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_803",
"caption_rating": "7"
},
{
"": "1005513",
"caption": "Nuclear stratification reaching the top of the epithelium with marked apoptosis.",
"image_path": "r7OA0Trj5hQ_image_37d22921-8a5f-4554-aff4-acc4b80f99cd.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Loss of mucin', 'Loss of cellular polarity', 'Nuclear stratification', 'Mitosis', 'Apoptosis']",
"noisy_text": " This is proliferative. With ATP or without ATP? With ATP? With invasion or without invasion? In this field, we cannot judge the invasion. So this is a proliferation with ATP. And see the glands stratify. And loss of mucin or less of mucin. And there is loss of polarity. Look at this nuclei running like in this direction. Look at this nuclei running in this direction. So clearly, loss of polarity. And the nuclear stratification is reaching the top of the epithelium, marked apoptosis. It's too thick to see the mitosis, but here you can see the mitosis. So this is stratification, loss of mucin, mitosis, apoptosis. So this",
"corrected_text": " This is proliferative. With ATP or without ATP? With ATP? With invasion or without invasion? In this field, we cannot judge the invasion. So this is a proliferation with ATP. And see the glands stratify. And loss of mucin or less of mucin. And there is loss of polarity. Look at this nuclei running like in this direction. Look at this nuclei running in this direction. So clearly, loss of polarity. And the nuclear stratification is reaching the top of the epithelium, marked apoptosis. It's too thick to see the mitosis, but here you can see the mitosis. So this is stratification, loss of mucin, mitosis, apoptosis. So this",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'proliferative cells', 'concept_id': 'C0334094', 'confidence': 0.8005025386810303}, {'entity': 'ATP', 'concept_id': 'C0001480', 'confidence': 1.0}, {'entity': 'hyperplastic glands', 'concept_id': 'C0020507', 'confidence': 0.7789753675460815}], [{'entity': 'Loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'mucin', 'concept_id': 'C0026682', 'confidence': 1.0}, {'entity': 'cellular polarity', 'concept_id': 'C0085304', 'confidence': 1.0}], [{'entity': 'Nuclear', 'concept_id': 'C0521447', 'confidence': 1.0}, {'entity': 'stratification', 'concept_id': 'C1514983', 'confidence': 1.0}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'apoptosis', 'concept_id': 'C0162638', 'confidence': 1.0}], [{'entity': 'Mitosis', 'concept_id': 'C0026255', 'confidence': 0.9999998807907104}, {'entity': 'stratification', 'concept_id': 'C1514983', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_804",
"caption_rating": "9"
},
{
"": "1005710",
"caption": "Epithelial and pseudoepithelial metaplasia and hyperplasia are present in the lesion.",
"image_path": "hoV-JkD6Wb0_image_ba400909-6dec-4a9b-9bf0-27f52d492e56.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['epithelial metaplasia', 'epithelial hyperplasia', 'nodular infiltrate', 'clear spaces', 'lymphocytes', 'plasma cells', 'epithelial metaplasia', 'epithelial hyperplasia', 'nodular infiltrate', 'clear spaces', 'lymphocytes', 'plasma cells']",
"noisy_text": " from this lesion that hopefully you had a chance to look at, quadricected shade biopsy. And one can see quite a bit of epithelial, pseudoepithelial metacyproplasia, epithelial hyperplasia. I think I'm going to flip the slide and look at the top piece in the dermis. And one can see we have a nodular infiltrate in the dermis, lots and lots of clear spaces centrally, and then some darker staining cells out at the periphery. And out at the periphery, we have a lot of lymphocytes and several scattered plasma cells. And if we look at the more clear staining areas, we can",
"corrected_text": " from this lesion that hopefully you had a chance to look at, excisional biopsy. And one can see quite a bit of epithelial, pseudoepithelial metaplasia, epithelial hyperplasia. I think I'm going to flip the slide and look at the top piece in the dermis. And one can see we have a nodular infiltrate in the dermis, lots and lots of clear spaces centrally, and then some darker staining cells out at the periphery. And out at the periphery, we have a lot of lymphocytes and several scattered plasma cells. And if we look at the more clear staining areas, we can",
"med_umls_ids": "[[{'entity': 'Epithelial', 'concept_id': 'C0221908', 'confidence': 1.0}, {'entity': 'pseudoepithelial metaplasia', 'concept_id': 'C1317977', 'confidence': 0.7813463807106018}, {'entity': 'hyperplasia', 'concept_id': 'C0020507', 'confidence': 1.0}, {'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}], [{'entity': 'Nodular infiltrate', 'concept_id': 'C0241130', 'confidence': 0.840809166431427}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'centrally', 'concept_id': 'C0205099', 'confidence': 0.7070305943489075}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'scattered', 'concept_id': 'C0439742', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_805",
"caption_rating": "8"
},
{
"": "1009399",
"caption": "Molecular pathology should not be used alone for diagnosis, but should be coupled with clinical scenario, histologic features, and immunohistochemistry findings.",
"image_path": "QDb68_G1HR4_image_d8885f68-50d4-4206-9c20-cccbea5b6876.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " But do be aware that there are many other tumors in soft tissue pathology that have FUS rearrangements, myxoid liposarcoma and others. They usually have a different histologic appearance. So that's why you can never use, at least in my opinion, you shouldn't use molecular pathology by itself. You have to couple it with the clinical scenario and the histologic features and the immunostain findings. Put all of the picture together and make sure that the diagnosis makes sense. If it doesn't make sense, I always try to stop and think what's wrong here? Is something not working? Is the test false positive? What's the problem? Why doesn't this all add up? Of course",
"corrected_text": " But do be aware that there are many other tumors in soft tissue pathology that have FUS gene rearrangements, myxoid liposarcoma and others. They usually have a different histologic appearance. So that's why you can never use, at least in my opinion, you shouldn't use molecular pathology by itself. You have to couple it with the clinical scenario and the histologic features and the immunostain findings. Put all of the picture together and make sure that the diagnosis makes sense. If it doesn't make sense, I always try to stop and think what's wrong here? Is something not working? Is the test false positive? What's the problem? Why doesn't this all add up? Of course",
"med_umls_ids": "[[{'entity': 'FUS', 'concept_id': 'C0268696', 'confidence': 1.0}, {'entity': 'gene rearrangements', 'concept_id': 'C0017287', 'confidence': 0.9999998807907104}, {'entity': 'soft tissue tumors', 'concept_id': 'C0037579', 'confidence': 1.0}, {'entity': 'myxoid liposarcoma', 'concept_id': 'C0206634', 'confidence': 1.0}], [{'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'FUS', 'concept_id': 'C0268696', 'confidence': 1.0}, {'entity': 'gene rearrangements', 'concept_id': 'C0017287', 'confidence': 0.9999998807907104}, {'entity': 'histologic', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}], [{'entity': 'Molecular pathology', 'concept_id': 'C0596962', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'coupled', 'concept_id': 'C1948027', 'confidence': 1.0}, {'entity': 'clinical scenario', 'concept_id': 'C0205210', 'confidence': 0.6381967067718506}, {'entity': 'histologic features', 'concept_id': 'C1301121', 'confidence': 0.816085159778595}, {'entity': 'immunohistochemistry', 'concept_id': 'C0021044', 'confidence': 0.9999998807907104}, {'entity': 'findings', 'concept_id': 'C2607943', 'confidence': 1.0}], [{'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_806",
"caption_rating": "9"
},
{
"": "1005561",
"caption": "The presence of a large cellular fibrohistiocytic infiltrate with collagen trapping and ring siderophages is indicative of a hemosiderotic or aneurysmal type of dermatofibroma, also known as a sclerosing hemangioma variant of a dermatofibroma. These lesions have a tendency to persist or recur if incompletely excised.",
"image_path": "8S4LeiO6Bbk_image_31316dc4-2661-4315-ae90-8b7ebfc79ec7.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Large cellular fibrohistiocytic infiltrate with collagen trapping and ring siderophages', 'Hemosiderotic or aneurysmal type of dermatofibroma', 'Punch biopsy specimen', 'Large cellular fibrohistiocytic infiltrate with collagen trapping and ring siderophages', 'Hemosiderotic or aneurysmal type of dermatofibroma', 'Punch biopsy specimen']",
"noisy_text": " know, we're not seeing any necrosis or an appreciable number of mitotic figures. And this large cellular fibrohystic-acidic infiltrate, again with the collagen trapping and ring siderophages out of the periphery, seems to be compressing the fat. And the constellation of features in these sections is pathognomonic, of course, or a hemociderotic or aneurysmal type of dermatofibroma, also known as a sclerosing hemangioma variant of a dermatofibroma. This is a type of cellular dermatofibroma. These lesions can get quite large and if incompletely excised do have a tendency to persist or recur. So good idea to completely excise these because they're certainly not going to go away on their own. A classic example, very commonly asked on boards and usually spoilers that you could expect in a question given this slide would include things like a blue nevus or melanoma or even nodular cap issues. So be familiar with the features of the hemociderotic variant of a dermatofibroma. Moving on to slide number five. This was kind of a cool case. We have a bisected punch biopsy specimen here. If we move into higher power, we can see that the epidermis",
"corrected_text": " know, we're not seeing any necrosis or an appreciable number of mitotic figures. And this large cellular fibrohystic-acidic infiltrate, again with the collagen trapping and ring siderophages out of the periphery, seems to be compressing the fat. And the constellation of features in these sections is pathognomonic, of course, or a hemosiderotic or aneurysmal type of dermatofibroma, also known as a sclerosing hemangioma variant of a dermatofibroma. This is a type of cellular dermatofibroma. These lesions can get quite large and if incompletely excised do have a tendency to persist or recur. So good idea to completely excise these because they're certainly not going to go away on their own. A classic example, very commonly asked on boards and usually spoilers that you could expect in a question given this slide would include things like a blue nevus or melanoma or even nodular cap issues. So be familiar with the features of the hemosiderotic variant of dermatofibroma of a dermatofibroma. Moving on to slide number five. This was kind of a cool case. We have a bisected punch biopsy specimen here. If we move into higher power, we can see that the epidermis",
"med_umls_ids": "[[{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'cellular fibrohistiocytic infiltrate', 'concept_id': 'C0019618', 'confidence': 0.7253735065460205}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'trapping', 'concept_id': 'C0282665', 'confidence': 0.8904784917831421}, {'entity': 'ring siderophages', 'concept_id': 'C1136253', 'confidence': 0.6553963422775269}, {'entity': 'hemosiderotic', 'concept_id': 'C0019114', 'confidence': 0.7758374810218811}, {'entity': 'aneurysmal type', 'concept_id': 'C0439651', 'confidence': 0.8459930419921875}, {'entity': 'dermatofibroma', 'concept_id': 'C0002991', 'confidence': 1.0}, {'entity': 'sclerosing', 'concept_id': 'C0036426', 'confidence': 0.833010733127594}, {'entity': 'hemangioma', 'concept_id': 'C0018916', 'confidence': 1.0}, {'entity': 'variant', 'concept_id': 'C0205419', 'confidence': 1.0}, {'entity': 'dermatofibroma', 'concept_id': 'C0002991', 'confidence': 1.0}, {'entity': 'lesions', 'concept_id': 'C0221198', 'confidence': 1.0}, {'entity': 'excised', 'concept_id': 'C1444670', 'confidence': 0.7215964794158936}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_807",
"caption_rating": "10"
},
{
"": "1004801",
"caption": "The lesion is likely a sebaceoma, which can be mistaken for basal cell carcinoma with sebaceous differentiation.",
"image_path": "udoW6VSqsm4_image_4483f4d9-3fdd-47b6-b585-c7025cc11c86.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['sebaceoma', 'basal cell carcinoma', 'sebaceous differentiation', 'sebaceoma', 'basal cell carcinoma', 'sebaceous differentiation']",
"noisy_text": " I think we've called it sebaceous epithelium, but again I'm not a big fan of that term. And these look usually like this. They're usually small, round, skin-colored leaves. They kind of look like sebaceous epithelium. They usually come in as real-life basins, so nobody diagnoses these clinically correctly. So these are items in the differential diagnosis. Basal cell with sebaceous differentiation, if you're going to make that diagnosis, it generally needs to look like a basal cell with nice clefting and put the palisade in there and all that, and then have foci where there's obvious sebaceous differentiation. You'll see that on occasion. But I would probably call this sebaceoma, without thinking it's sort of synonymous with sebaceous epithelium. Now, is there any condition you have to worry about with these? With any",
"corrected_text": " I think we've called it sebaceous epithelium, but again I'm not a big fan of that term. And these look usually like this. They're usually small, round, skin-colored leaves. They kind of look like sebaceous epithelium. They usually come in as real-life basins, so nobody diagnoses these clinically correctly. So these are items in the differential diagnosis. Basal cell with sebaceous differentiation, if you're going to make that diagnosis, it generally needs to look like a basal cell with nice clefting and put the palisade in there and all that, and then have foci where there's obvious sebaceous differentiation. You'll see that on occasion. But I would probably call this sebaceoma, without thinking it's sort of synonymous with sebaceous epithelium. Now, is there any condition you have to worry about with these? With any",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'sebaceoma', 'concept_id': 'C1275210', 'confidence': 1.0}, {'entity': 'basal cell carcinoma', 'concept_id': 'C0007117', 'confidence': 1.0}, {'entity': 'sebaceous differentiation', 'concept_id': 'C1882988', 'confidence': 1.0}], [{'entity': 'Sebaceomas', 'concept_id': 'C1275210', 'confidence': 0.8855459690093994}, {'entity': 'small', 'concept_id': 'C0700321', 'confidence': 0.9999998807907104}, {'entity': 'round', 'concept_id': 'C0332490', 'confidence': 1.0}, {'entity': 'skin-colored', 'concept_id': 'C4476819', 'confidence': 0.8005288243293762}], [{'entity': 'Basal cell carcinoma', 'concept_id': 'C0007117', 'confidence': 1.0}, {'entity': 'sebaceous differentiation', 'concept_id': 'C1882988', 'confidence': 1.0}, {'entity': 'clefting', 'concept_id': 'C4021813', 'confidence': 0.8906428217887878}, {'entity': 'palisading', 'concept_id': 'C1622240', 'confidence': 0.8684062361717224}, {'entity': 'sebaceous differentiation', 'concept_id': 'C1882988', 'confidence': 1.0}], [{'entity': 'conditions', 'concept_id': 'C0012634', 'confidence': 0.8556983470916748}, {'entity': 'concern', 'concept_id': 'C2699424', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_808",
"caption_rating": "8"
},
{
"": "1004707",
"caption": "Presence of eosinophils and band interrupts inflammatory cells and capillaries.",
"image_path": "sDFjOtMAYrk_image_bf11cb9b-379e-4afd-b476-37b8ad9a35e7.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['Thick and irregular band with feet-like projections into the lamina propria.']",
"noisy_text": " and some eos. And what else? Yeah, exactly. So the band interrupts inflammatory cells and capillaries, and it's not just the thickness of the band that really catches your eyes, the irregularity of it. So you don't have a thin smooth line anymore. It's just, you know, thick and irregular, just just throwing like feet down into the, into the lamina appropriate. There are also a few lymphocytes in the epithelium, but that's not the main finding. The other thing you might find in some of these is some degree of active inflammation. And let",
"corrected_text": " and some eos. And what else? Yeah, exactly. So the band interrupts inflammatory cells and capillaries, and it's not just the thickness of the band that really catches your eyes, the irregularity of it. So you don't have a thin smooth line anymore. It's just, you know, thick and irregular, just just throwing like feet down into the, into the lamina appropriate. There are also a few lymphocytes in the epithelium, but that's not the main finding. The other thing you might find in some of these is some degree of active inflammation. And let",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'band', 'concept_id': 'C0175723', 'confidence': 1.0}, {'entity': 'inflammatory cells', 'concept_id': 'C0440752', 'confidence': 1.0}, {'entity': 'capillaries', 'concept_id': 'C0006901', 'confidence': 0.9999998807907104}], [{'entity': 'Thick', 'concept_id': 'C1280412', 'confidence': 1.0}, {'entity': 'irregular', 'concept_id': 'C0205271', 'confidence': 1.0}, {'entity': 'projections', 'concept_id': 'C0016538', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'active', 'concept_id': 'C0205177', 'confidence': 1.0}, {'entity': 'inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_809",
"caption_rating": "7"
},
{
"": "1009489",
"caption": "The deep, large aggregations of clear staining cells with cuticular areas inside the ducts resemble a syringoma.",
"image_path": "LlPaENuqzVQ_image_c623b28d-db14-4019-bd1e-3ca9b5092c16.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['Aggregations of cells resembling a syringoma.']",
"noisy_text": " except it's pretty deep, large and deep. Yeah, you're right. So if you look at the individual aggregations of cells, they do look a lot like a syringoma. That's clear staining cells here. They've got these little cuticular areas inside the ducts like you see here. And basically, another name for MAC that I actually like better is syringomatous carcinoma because it looks like a syringoma. And if you look at the individual cells, usually you don't see a lot of mitoses. There's not a lot of individual cellular atypia, not a lot of pleomorphism. It's really a neoplasm that causes problems because of",
"corrected_text": " except it's pretty deep, large and deep. Yeah, you're right. So if you look at the individual aggregations of cells, they do look a lot like a syringoma. That's clear staining cells here. They've got these little cuticular areas inside the ducts like you see here. And basically, another name for MAC that I actually like better is syringomatous carcinoma because it looks like a syringoma. And if you look at the individual cells, usually you don't see a lot of mitoses. There's not a lot of individual cellular atypia, not a lot of pleomorphism. It's really a neoplasm that causes problems because of",
"med_umls_ids": "[[{'entity': 'deep', 'concept_id': 'C0205125', 'confidence': 0.9999999403953552}, {'entity': 'aggregations', 'concept_id': 'C0332621', 'confidence': 0.9210782051086426}, {'entity': 'clear staining cells', 'concept_id': 'C0229473', 'confidence': 0.7975835800170898}, {'entity': 'cuticular areas', 'concept_id': 'C2699479', 'confidence': 0.6761574745178223}, {'entity': 'ducts', 'concept_id': 'C0687028', 'confidence': 1.0}, {'entity': 'syringoma', 'concept_id': 'C0206673', 'confidence': 1.0}], [{'entity': 'MAC', 'concept_id': 'C0009545', 'confidence': 0.9999999403953552}, {'entity': 'mucinous adenocarcinoma', 'concept_id': 'C0007130', 'confidence': 1.0}, {'entity': 'syringomatous carcinoma', 'concept_id': 'C0346027', 'confidence': 1.0}], [{'entity': 'MAC/syringomatous carcinoma', 'concept_id': 'C0346027', 'confidence': 0.7567015886306763}, {'entity': 'mitoses', 'concept_id': 'C0026255', 'confidence': 1.0}, {'entity': 'cellular atypia/pleomorphism', 'concept_id': 'C1707333', 'confidence': 0.6986897587776184}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_810",
"caption_rating": "8"
},
{
"": "1006815",
"caption": "Presence of acinar structures resembling pancreas in the stomach is known as pancreatic acinar metaplasia.",
"image_path": "r7OA0Trj5hQ_image_ed71e498-cdc8-4f2a-90c3-46df67558a93.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Peritoneal cells in gastric fundic mucosa or gastric corpus mucosa', 'Acinar structures resembling pancreas in the stomach', 'Pancreatic acinar-like structures in the GIT', 'Acinar structures resembling pancreas in the stomach']",
"noisy_text": " These are the peritoneal cells. When you don't see the peritoneal cells in the gastric fundic mucosa or gastric corpus mucosa, then you have to call it as pyloric metaplasia. This is very, very important because you see it in autoimmune gastritis. Sometimes the stomach can show acinar structures resembling pancreas. Then it is known as pancreatic acinar metaplasia. This can also happen in the small intestine. There, when you do staining for amylase or trypsin, it will be positive, but on H&E itself, you can see pancreatic acinar-like structures in the GIT. Then it will become pancreatic acinar metaplasia. Here is the",
"corrected_text": " These are the peritoneal cells. When you don't see the peritoneal cells in the gastric fundic mucosa or gastric corpus mucosa, then you have to call it as pyloric metaplasia. This is very, very important because you see it in autoimmune gastritis. Sometimes the stomach can show acinar structures resembling pancreas. Then it is known as pancreatic acinar metaplasia. This can also happen in the small intestine. There, when you do staining for amylase or trypsin, it will be positive, but on H&E itself, you can see pancreatic acinar-like structures in the GIT. Then it will become pancreatic acinar metaplasia. Here is the",
"med_umls_ids": "[[{'entity': 'Absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'peritoneal cells', 'concept_id': 'C0031153', 'confidence': 0.7749612331390381}, {'entity': 'gastric fundic mucosa', 'concept_id': 'C0017136', 'confidence': 0.8429272770881653}, {'entity': 'gastric corpus mucosa', 'concept_id': 'C0735811', 'confidence': 0.9813486337661743}, {'entity': 'pyloric metaplasia', 'concept_id': 'C4288813', 'confidence': 0.8951747417449951}, {'entity': 'autoimmune gastritis', 'concept_id': 'C3887639', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'acinar structures', 'concept_id': 'C0678594', 'confidence': 0.7908228039741516}, {'entity': 'pancreas', 'concept_id': 'C0030274', 'confidence': 0.9999999403953552}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'pancreatic acinar metaplasia', 'concept_id': 'C4021967', 'confidence': 0.7844848036766052}], [{'entity': 'Pancreatic acinar metaplasia', 'concept_id': 'C4021967', 'confidence': 0.7844848036766052}, {'entity': 'small', 'concept_id': 'C0700321', 'confidence': 0.9999998807907104}, {'entity': 'intestine', 'concept_id': 'C0021853', 'confidence': 1.0}, {'entity': 'staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'amylase', 'concept_id': 'C0002712', 'confidence': 1.0}, {'entity': 'trypsin', 'concept_id': 'C0041236', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_811",
"caption_rating": "8"
},
{
"": "1007331",
"caption": "Presence of internal elastic lamina indicates artery, while its absence indicates vein.",
"image_path": "r7OA0Trj5hQ_image_d9ce62c4-cc39-4986-a75b-6fa933f93feb.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " In high power, you can see very thick vessel wall with the narrowing of the lumen, whereas here, it is relatively preserved. So you want to know whether it is a vein or artery. Please believe me, this is a vein, and this is an artery. And that is proved by the elastic tissue strain. These are all pictures from Dr. Gonzalez's Twitter. And you can see here, there is no internal elastic lamina, whereas here, there is an internal elastic lamina. So this is a branch of mesenteric artery, whereas this is a branch of mesenteric vein. And there is a condition called as idiopathic myointimal hyperplasia of the mesenteric vein. I don't know how many of you have heard this company. There's a",
"corrected_text": " In high power, you can see very thick vessel wall with the narrowing of the lumen, whereas here, it is relatively preserved. So you want to know whether it is a vein or artery. Please believe me, this is a vein, and this is an artery. And that is proved by the elastic tissue strain. These are all pictures from Dr. Gonzalez's Twitter. And you can see here, there is no internal elastic lamina, whereas here, there is an internal elastic lamina. So this is a branch of mesenteric artery, whereas this is a branch of mesenteric vein. And there is a condition called as idiopathic myointimal hyperplasia of mesenteric vein of the mesenteric vein. I don't know how many of you have heard this company. There's a",
"med_umls_ids": "[[{'entity': 'Thick vessel wall', 'concept_id': 'C1180033', 'confidence': 0.6420797109603882}, {'entity': 'lumen', 'concept_id': 'C0524461', 'confidence': 0.9999998807907104}, {'entity': 'power', 'concept_id': 'C0032863', 'confidence': 1.0}], [{'entity': 'Identification', 'concept_id': 'C0020792', 'confidence': 1.0}, {'entity': 'vein', 'concept_id': 'C0042449', 'confidence': 1.0}, {'entity': 'artery', 'concept_id': 'C0003842', 'confidence': 1.0}, {'entity': 'elastic tissue', 'concept_id': 'C0013762', 'confidence': 1.0}, {'entity': 'strain', 'concept_id': 'C0080194', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'internal elastic lamina', 'concept_id': 'C1180561', 'confidence': 1.0}, {'entity': 'artery', 'concept_id': 'C0003842', 'confidence': 1.0}, {'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'vein', 'concept_id': 'C0042449', 'confidence': 1.0}], [{'entity': 'Branches', 'concept_id': 'C1182977', 'confidence': 0.7288598418235779}, {'entity': 'mesenteric artery', 'concept_id': 'C0025465', 'confidence': 1.0}, {'entity': 'vein', 'concept_id': 'C0042449', 'confidence': 1.0}, {'entity': 'examples', 'concept_id': 'C1707959', 'confidence': 0.8639216423034668}], [{'entity': 'Idiopathic myointimal hyperplasia', 'concept_id': 'C0333978', 'confidence': 0.8139097094535828}, {'entity': 'mesenteric vein', 'concept_id': 'C0025473', 'confidence': 1.0}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_812",
"caption_rating": "7"
},
{
"": "1007214",
"caption": "Not all prostate tumors are primary, some can be secondary from a distant site.",
"image_path": "iklRyY1nBIE_image_550ce02e-2076-49b3-b29e-570bdd51b7e3.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['cutaneous structures', 'squamous pearls', 'cartilage', 'chondroit component', 'adnexal structures']",
"noisy_text": " So remember, this is still in the prostate. So you see a lot of cutaneous structures. You see squamous pearls. You're beginning to see cartilage, because it looks like chondroit component to it, possible adnexal structures. So I think this gave the diagnosis away. This is a metastatic malignant teratoma to the prostate. I know it's not something you see every day, but I thought it would be an interesting case to show you, just to make the point that not all prosthetic tumors are primary. You can also have secondary prosthetic tumors. And they're not always from the usual suspects. They're not always from the bladder or the colorectum. You can have tumors metastasized into the process from a distant site. I talked about melanoma earlier, but in younger patients, it's not unusual to have this kind of scenario. It's rare, but you should always keep an open mind sometimes. So this patient actually had a malignant mixed germ cell tumor, got therapy, and unfortunately, had the teratoma. And this",
"corrected_text": " So remember, this is still in the prostate. So you see a lot of cutaneous structures. You see squamous pearls. You're beginning to see cartilage, because it looks like chondroit component to it, possible adnexal structures. So I think this gave the diagnosis away. This is a metastatic malignant teratoma to the prostate. I know it's not something you see every day, but I thought it would be an interesting case to show you, just to make the point that not all prosthetic tumors are primary. You can also have secondary prosthetic tumors. And they're not always from the usual suspects. They're not always from the bladder or the colon or rectum. You can have tumors metastasized into the process from a distant site. I talked about melanoma earlier, but in younger patients, it's not unusual to have this kind of scenario. It's rare, but you should always keep an open mind sometimes. So this patient actually had a malignant mixed germ cell tumor, got therapy, and unfortunately, had the teratoma. And this",
"med_umls_ids": "[[{'entity': 'Metastatic malignant teratoma', 'concept_id': 'C0334520', 'confidence': 0.8136225938796997}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'prostate tumors', 'concept_id': 'C0033578', 'confidence': 1.0}, {'entity': 'primary', 'concept_id': 'C0205225', 'confidence': 1.0}, {'entity': 'secondary', 'concept_id': 'C0027627', 'confidence': 1.0}, {'entity': 'distant site', 'concept_id': 'C0449639', 'confidence': 0.8222140669822693}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_813",
"caption_rating": "8"
},
{
"": "1004414",
"caption": "Ganglion cells are also important in the diagnosis of congenital megacolon.",
"image_path": "r7OA0Trj5hQ_image_391ca795-2aab-4b66-9f24-6486937d85d6.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['neural hypertrophy', 'ganglion cells', 'submucosa', 'congenital megacolon', 'submucosa']",
"noisy_text": " for example, carotid endoartrectomy or abdominal aortic encephalopathy, that history is very important for cholesterol emboli. Here, there is more like a neural hypertrophy. Whenever you see neural hypertrophy, you have to think of Crohn's disease. Here, you see the ganglion cells in the submicosa. When you see ganglion cells, these are normal component of the submicosa. And why I am showing it, sometimes you may think of malignancy. Here, you may not think of it. And another point, these are all the cells we are looking in congenital mecagola. So if you don't see them in the submicosa in frozen section, again, this will qualify for congenital mecagola. Here, another tricky thing. This is",
"corrected_text": " for example, carotid endarterectomy or abdominal aortic encephalopathy, that history is very important for cholesterol emboli. Here, there is more like a neural hypertrophy. Whenever you see neural hypertrophy, you have to think of Crohn's disease. Here, you see the ganglion cells in the submucosa. When you see ganglion cells, these are normal component of the submucosa. And why I am showing it, sometimes you may think of malignancy. Here, you may not think of it. And another point, these are all the cells we are looking in congenital megacolon. So if you don't see them in the submucosa in frozen section, again, this will qualify for congenital megacolon. Here, another tricky thing. This is",
"med_umls_ids": "[[{'entity': 'History', 'concept_id': 'C0019664', 'confidence': 1.0}, {'entity': 'carotid endarterectomy', 'concept_id': 'C0014099', 'confidence': 1.0}, {'entity': 'abdominal aortic encephalopathy', 'concept_id': 'C0507867', 'confidence': 0.6308470964431763}, {'entity': 'cholesterol emboli', 'concept_id': 'C0149649', 'confidence': 0.8653062582015991}], [{'entity': 'Neural hypertrophy', 'concept_id': 'C0020564', 'confidence': 0.8345715999603271}, {'entity': \"Crohn's disease\", 'concept_id': 'C0010346', 'confidence': 1.0}], [{'entity': 'Ganglion cells', 'concept_id': 'C0228071', 'confidence': 1.0}, {'entity': 'submucosa', 'concept_id': 'C0225344', 'confidence': 1.0}, {'entity': 'malignancy', 'concept_id': 'C0006826', 'confidence': 1.0}], [{'entity': 'Ganglion cells', 'concept_id': 'C0228071', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'congenital megacolon', 'concept_id': 'C0019569', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_814",
"caption_rating": "8"
},
{
"": "1007506",
"caption": "The biopsy is pathologic with mitosis and apoptosis.",
"image_path": "r7OA0Trj5hQ_image_bd30a56c-9ede-4390-9b00-008bb58560e4.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " that is pathologic in this biopsy. And there is mitosis and apoptosis. Remember, these four criteria for dysplasia. See again here, stratification has started. But you see, mucin is less. It is, I won't say lost. It is less. And this stratified nuclei reach the middle third. They are not touching the upper top of the apical membrane. They are reaching the middle third predominantly. Okay, that is one important point. And other one is, look at this nuclei. They are all traveling in one direction. So the polarity is maintained. Okay, so those two points are very important. And the third one",
"corrected_text": " that is pathologic in this biopsy. And there is mitosis and apoptosis. Remember, these four criteria for dysplasia. See again here, stratification has started. But you see, mucin is less. It is, I won't say lost. It is less. And this stratified nuclei reach the middle third. They are not touching the upper top of the apical membrane. They are reaching the middle third predominantly. Okay, that is one important point. And other one is, look at this nuclei. They are all traveling in one direction. So the polarity is maintained. Okay, so those two points are very important. And the third one",
"med_umls_ids": "[[{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'pathologic', 'concept_id': 'C1521733', 'confidence': 1.0}, {'entity': 'mitosis', 'concept_id': 'C0026255', 'confidence': 0.9999998807907104}, {'entity': 'apoptosis', 'concept_id': 'C0162638', 'confidence': 1.0}], [{'entity': 'Stratification', 'concept_id': 'C1514983', 'confidence': 1.0}, {'entity': 'started', 'concept_id': 'C1272689', 'confidence': 0.9999999403953552}, {'entity': 'mucin', 'concept_id': 'C0026682', 'confidence': 1.0}], [{'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'middle', 'concept_id': 'C0227972', 'confidence': 1.0}, {'entity': 'polarity', 'concept_id': 'C0596963', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_815",
"caption_rating": "7"
},
{
"": "1007862",
"caption": "There is loss of the cornified layer.",
"image_path": "udoW6VSqsm4_image_d6b4ac1d-f599-4c3a-8e61-a2c9de93d69d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['loss of the cornified layer']",
"noisy_text": " And so, the other things we kind of talked about are a bit differential, but next slide. Nothing else really will give you this kind of localized circumscribed area like this, so it's not poro. That would have a coronal lamella with granulocidal abnormalities and dyskeratonic keratinocytes. We don't see that here, so this is just a loss of the coronified layer. And there's one other condition where you kind of get, where are some other little clonal, you know, somatic mutations that you can get abnormalities in the epithelium that occur just in localized areas. That's not like loss of the coronified layer. We'll put a couple of other diseases where you see just local areas that are abnormal, and you get normal skin to the side. So, poro is one. We'll put",
"corrected_text": " And so, the other things we kind of talked about are a bit differential, but next slide. Nothing else really will give you this kind of localized circumscribed area like this, so it's not poro. That would have a coronal lamella with granulomatous abnormalities and dyskeratotic keratinocytes. We don't see that here, so this is just a loss of the cornified layer. And there's one other condition where you kind of get, where are some other little clonal, you know, somatic mutations that you can get abnormalities in the epithelium that occur just in localized areas. That's not like loss of the cornified layer. We'll put a couple of other diseases where you see just local areas that are abnormal, and you get normal skin to the side. So, poro is one. We'll put",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'localized', 'concept_id': 'C0392752', 'confidence': 1.0}, {'entity': 'circumscribed area', 'concept_id': 'C1282914', 'confidence': 0.9260231852531433}, {'entity': 'granulomatous abnormalities', 'concept_id': 'C0439667', 'confidence': 0.7099277377128601}, {'entity': 'dyskeratotic keratinocytes', 'concept_id': 'C1512099', 'confidence': 0.9701507091522217}, {'entity': 'porokeratosis', 'concept_id': 'C0162839', 'confidence': 1.0}], [{'entity': 'loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'cornified layer', 'concept_id': 'C3554359', 'confidence': 0.8562335968017578}], [{'entity': 'conditions', 'concept_id': 'C0012634', 'confidence': 0.8556983470916748}, {'entity': 'localized', 'concept_id': 'C0392752', 'confidence': 1.0}, {'entity': 'abnormality', 'concept_id': 'C1704258', 'confidence': 1.0}, {'entity': 'somatic mutations', 'concept_id': 'C0544886', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_816",
"caption_rating": "8"
},
{
"": "1005762",
"caption": "Description of normal colonic glands and crypts with no lymphocytes, plasma cells, or eosinophils. The amount of lamina propria in between the crypts is the same as you move from one crypt to another.",
"image_path": "sDFjOtMAYrk_image_5f486045-06ed-4a5e-8e56-1022cf892b7a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['colonic crypts', 'muscularis mucosa', 'lamina propria', 'colonic crypts', 'muscularis mucosa', 'lamina propria', 'colonic crypts', 'muscularis mucosa', 'lamina propria']",
"noisy_text": " fellows about normal. What I like to see are these colonic glands. Do we have an arrow? Oh, yes. It should. Is he not coming up? No. Oh, you have to turn it on. No, it's not coming up. Yeah, it is. Yeah, here you go. Just the red one. Yeah. Oh, I don't see it. It's okay. Is the mouse going to work? Yeah, I'll do the mouse. Yeah, it works. Okay. Basically, I like to see my colonic crypts nice and straight coming from the surface, trying to kiss that muscularis mucosa underneath in between the crypts and the muscularis mucosa. I don't want to see any lymphocytes, plasma cells, eosinophils. You can have one or two. That's okay, but typically no basal lymphoplasma cytosis. The other thing I like to point out is the amount of lamina propria in between the crypts is the same as you move from one crypt to another. The crypts stand equidistant one from another. Remember the differences between the cecum or the right colon and the left colon. This is a biopsy from the segment and shows",
"corrected_text": " fellows about normal. What I like to see are these colonic glands. Do we have an arrow? Oh, yes. It should. Is he not coming up? No. Oh, you have to turn it on. No, it's not coming up. Yeah, it is. Yeah, here you go. Just the red one. Yeah. Oh, I don't see it. It's okay. Is the mouse going to work? Yeah, I'll do the mouse. Yeah, it works. Okay. Basically, I like to see my colonic crypts nice and straight coming from the surface, trying to kiss that muscularis mucosa underneath in between the crypts and the muscularis mucosa. I don't want to see any lymphocytes, plasma cells, eosinophils. You can have one or two. That's okay, but typically no basal lymphoplasma cytosis. The other thing I like to point out is the amount of lamina propria in between the crypts is the same as you move from one crypt to another. The crypts stand equidistant one from another. Remember the differences between the cecum or the right colon and the left colon. This is a biopsy from the segment and shows",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'colonic glands', 'concept_id': 'C0227351', 'confidence': 0.8191195130348206}, {'entity': 'crypts', 'concept_id': 'C0227427', 'confidence': 0.9071587324142456}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'amount', 'concept_id': 'C1265611', 'confidence': 0.9999998807907104}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'crypts', 'concept_id': 'C0227427', 'confidence': 0.9071587324142456}, {'entity': 'crypt', 'concept_id': 'C1880192', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_817",
"caption_rating": "9"
},
{
"": "1009248",
"caption": "High power view shows apoptosis and mitosis, diagnostic criteria for dysplasia.",
"image_path": "r7OA0Trj5hQ_image_716d9277-9b40-4609-9393-0ad09ceba939.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Stratification and loss of mucin seen in one area.', 'Stratification and loss of mucin seen in one area.']",
"noisy_text": " Here, single layer of cells, mucin is present, whereas here, stratification has started, loss of mucin. So stratification, loss of mucin. And when you go to high power, you can see lot of apoptosis and lot of mitosis. So this is a diagnostic criteria for dysplasia. Stratification, loss of mucin. See the amount of goblet cells, mucin. You see the amount of goblet cells. This loss of mucin or less of mucin. Again, another normal epithelium. So this is the area, pyramidal area, that is pathologic in this biopsy. And there",
"corrected_text": " Here, single layer of cells, mucin is present, whereas here, stratification has started, loss of mucin. So stratification, loss of mucin. And when you go to high power, you can see lot of apoptosis and lot of mitosis. So this is a diagnostic criteria for dysplasia. Stratification, loss of mucin. See the amount of goblet cells, mucin. You see the amount of goblet cells. This loss of mucin or less of mucin. Again, another normal epithelium. So this is the area, pyramidal area, that is pathologic in this biopsy. And there",
"med_umls_ids": "[[{'entity': 'Single layer of', 'concept_id': 'C0934502', 'confidence': 0.6987537741661072}, {'entity': 'mucin', 'concept_id': 'C0026682', 'confidence': 1.0}, {'entity': 'stratification', 'concept_id': 'C1514983', 'confidence': 1.0}, {'entity': 'loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'mucin', 'concept_id': 'C0026682', 'confidence': 1.0}, {'entity': 'area', 'concept_id': 'C0017446', 'confidence': 1.0}], [{'entity': 'apoptosis', 'concept_id': 'C0162638', 'confidence': 1.0}, {'entity': 'mitosis', 'concept_id': 'C0026255', 'confidence': 0.9999998807907104}, {'entity': 'diagnostic criteria', 'concept_id': 'C0679228', 'confidence': 1.0}, {'entity': 'dysplasia', 'concept_id': 'C0334044', 'confidence': 1.0}], [{'entity': 'Amount', 'concept_id': 'C1265611', 'confidence': 0.9999998807907104}, {'entity': 'goblet cells', 'concept_id': 'C0506994', 'confidence': 0.9999999403953552}, {'entity': 'mucin', 'concept_id': 'C0026682', 'confidence': 1.0}, {'entity': 'normal epithelium', 'concept_id': 'C0014609', 'confidence': 0.8199569582939148}], [{'entity': 'Pyramidal area', 'concept_id': 'C2323328', 'confidence': 0.8333803415298462}, {'entity': 'pathologic', 'concept_id': 'C1521733', 'confidence': 1.0}, {'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_818",
"caption_rating": "8"
},
{
"": "1004777",
"caption": "The patient in the case had positive nucleic acid amplification testing for chlamydia, indicating a sexually transmitted infectious proctitis.",
"image_path": "sDFjOtMAYrk_image_aec6939d-1a5a-413f-9b4d-0748696ed537.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['positive nucleic acid amplification testing for chlamydia', 'sexually transmitted infectious proctitis', 'inflammation', 'positive nucleic acid amplification testing for chlamydia', 'sexually transmitted infectious proctitis', 'inflammation']",
"noisy_text": " infection maybe or any type of infection. So not a bad idea always to look for your CMV. Yeah. But the other thing that we're seeing a resurgence of is of sexually transmitted infectious proctitis, namely syphilis and chlamydia. And this is a bit of an abnormal case because actually Dr. Montgomery got this case and she showed it to me and said, I think this is probably STI. And I said, well, it's really, really inflamed for STI. And lo and behold, she was right. The patient had positive nucleic acid amplification testing for chlamydia. Plus, he had",
"corrected_text": " infection maybe or any type of infection. So not a bad idea always to look for your CMV. Yeah. But the other thing that we're seeing a resurgence of is of sexually transmitted infectious proctitis, namely syphilis and chlamydia. And this is a bit of an abnormal case because actually Dr. Montgomery got this case and she showed it to me and said, I think this is probably STI. And I said, well, it's really, really inflamed for STI. And lo and behold, she was right. The patient had positive nucleic acid amplification testing for chlamydia. Plus, he had",
"med_umls_ids": "[[{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'nucleic acid amplification testing', 'concept_id': 'C0200932', 'confidence': 0.938366174697876}, {'entity': 'chlamydia', 'concept_id': 'C0008148', 'confidence': 1.0}, {'entity': 'sexually transmitted', 'concept_id': 'C1519280', 'confidence': 0.9033694863319397}, {'entity': 'infectious proctitis', 'concept_id': 'C0400831', 'confidence': 0.8619710206985474}], [{'entity': 'STI-related proctitis', 'concept_id': 'C0537521', 'confidence': 0.6025350689888}, {'entity': 'inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_819",
"caption_rating": "9"
},
{
"": "1006276",
"caption": "Identification of different types of protein fibers in connective tissue.",
"image_path": "ib991vTA67A_image_a63162a5-2a38-4225-964d-be807514f435.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Head and Neck']",
"roi_text": "['Connective Tissue', 'skinny collagen fibers', 'fat, fatter, thick, pink protein fibers']",
"noisy_text": " and three places where you could find this type of Connective Tissue. So here's this Connective Tissue again, just write it down, and the next question is what type of protein fibers are these skinny ones, these skinny hair-like protein fibers? Find those protein fibers first, the skinny hair-like protein fibers, what are those called? And next, what are these fat, fatter, thick, pink protein fibers called? What are these protein fibers called? Here's a close-up of a Connective Tissue you've seen, so this is going to be number twenty-four, what type",
"corrected_text": " and three places where you could find this type of Connective Tissue. So here's this Connective Tissue again, just write it down, and the next question is what type of protein fibers are these skinny ones, these skinny hair-like protein fibers? Find those protein fibers first, the skinny hair-like protein fibers, what are those called? And next, what are these fat, fatter, thick, pink protein fibers called? What are these protein fibers called? Here's a close-up of a Connective Tissue you've seen, so this is going to be number twenty-four, what type",
"med_umls_ids": "[[{'entity': 'Identification', 'concept_id': 'C0020792', 'confidence': 1.0}, {'entity': 'protein fibers', 'concept_id': 'C0000696', 'confidence': 0.7645217180252075}, {'entity': 'connective tissue', 'concept_id': 'C0009780', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1152.0",
"id": "test_820",
"caption_rating": "8"
},
{
"": "1007114",
"caption": "Loss of surface epithelial injury and mucin, and expanded lamina propria can make tissue appear blue.",
"image_path": "sDFjOtMAYrk_image_0ccbf22b-291f-4fef-bebf-ca52a3de83bf.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['surface epithelial injury', 'superficial mucin', 'lamina propria', 'syncytial-like surface epithelium', 'intrapithelial cells', 'surface epithelial injury', 'superficial mucin', 'lamina propria', 'syncytial-like surface epithelium', 'intrapithelial cells']",
"noisy_text": " We just know what is normal and what too much is too much. Besides having that, the low power appearance, of course, will have a lack of significant architectural distortion. And you will see it will look a little bit blue. Where's my arrow? It will look somewhat blue at low power because there's loss of surface epithelial injury, loss of superficial mucin, and the lamina propria will be expanded. That's one case. And here's another, a little bit more of a dramatic appearance with really, really good syncytial-like looking surface epithelial with tons of intrapithelial lymphocytes and",
"corrected_text": " We just know what is normal and what too much is too much. Besides having that, the low power appearance, of course, will have a lack of significant architectural distortion. And you will see it will look a little bit blue. Where's my arrow? It will look somewhat blue at low power because there's loss of surface epithelial injury, loss of superficial mucin, and the lamina propria will be expanded. That's one case. And here's another, a little bit more of a dramatic appearance with really, really good syncytial-like looking surface epithelial with tons of intrapithelial lymphocytes and",
"med_umls_ids": "[[{'entity': 'Low', 'concept_id': 'C0205251', 'confidence': 0.9999999403953552}, {'entity': 'power', 'concept_id': 'C0032863', 'confidence': 1.0}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'normal tissue', 'concept_id': 'C0040300', 'confidence': 0.9999999403953552}, {'entity': 'lack', 'concept_id': 'C0332268', 'confidence': 1.0}, {'entity': 'architectural', 'concept_id': 'C0003737', 'confidence': 0.8758222460746765}], [{'entity': 'Loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'mucin', 'concept_id': 'C0026682', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'blue', 'concept_id': 'C1260957', 'confidence': 1.0}], [{'entity': 'Syncytial-like surface epithelium', 'concept_id': 'C1182809', 'confidence': 0.6702060103416443}, {'entity': 'intrapithelial cells', 'concept_id': 'C0014597', 'confidence': 0.7846651077270508}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_821",
"caption_rating": "7"
},
{
"": "1005942",
"caption": "Vessels are compressed in peripheral and beneath the central zone.",
"image_path": "8S4LeiO6Bbk_image_5e4d9616-68f1-4771-aa97-50575d8a7114.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['papillary projections', 'extravasated erythrocytes', 'dilated vessels', 'enlarged endothelial cells', 'collagen bundles', 'pre-existing vascular spaces', 'papillary projections', 'extravasated erythrocytes', 'dilated vessels', 'enlarged endothelial cells', 'collagen bundles', 'pre-existing vascular spaces', 'papillary projections', 'extravasated erythrocytes', 'dilated vessels', 'enlarged endothelial cells', 'collagen bundles', 'pre-existing vascular spaces']",
"noisy_text": " into the limina. If you look around, you can see these papillary projections. There are a few extravasated erythrocytes present within the stroma. So clearly, we've got this vascular neoplasma here with these dilated endothelial line spaces, but it's got kind of a bifasic pattern. Centrally, we've got these dilated vessels, but peripheral and beneath that zone, the vessels are somewhat more compressed. They're still lined by some of the plump endothelial cells. And in these various where the vessels are compressed, they kind of appear to dissect between collagen bundles. We even have a little bit of a promontory sign here where we've got these vessels surrounding pre-existing vascular spaces. But unlike the neovascular spaces that we see in Kaposi's sarcoma, the endothelial cells here are a little more plump, and we don't have plasma cells within the infiltrate. And plasma cells within the infiltrate can be very useful in discriminating between this condition and Kaposi's sarcoma. In this particular case, also the HHV8 stain was a negative, which",
"corrected_text": " into the limina. If you look around, you can see these papillary projections. There are a few extravasated erythrocytes present within the stroma. So clearly, we've got this vascular neoplasm here with these dilated endothelial line spaces, but it's got kind of a biphasic pattern. Centrally, we've got these dilated vessels, but peripheral and beneath that zone, the vessels are somewhat more compressed. They're still lined by some of the enlarged endothelial cells. And in these various where the vessels are compressed, they kind of appear to dissect between collagen bundles. We even have a little bit of a promontory sign here where we've got these vessels surrounding pre-existing vascular spaces. But unlike the neovascularization that we see in Kaposi's sarcoma, the endothelial cells here are a little more plump, and we don't have plasma cells within the infiltrate. And plasma cells within the infiltrate can be very useful in discriminating between this condition and Kaposi's sarcoma. In this particular case, also the HHV8 stain was a negative, which",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'vascular neoplasm', 'concept_id': 'C0027668', 'confidence': 1.0}, {'entity': 'dilated endothelial line spaces', 'concept_id': 'C0014257', 'confidence': 0.6450937390327454}, {'entity': 'biphasic pattern', 'concept_id': 'C1332555', 'confidence': 1.0}], [{'entity': 'Vessels', 'concept_id': 'C0005847', 'confidence': 1.0}, {'entity': 'peripheral', 'concept_id': 'C0205100', 'confidence': 1.0}, {'entity': 'central zone', 'concept_id': 'C0458698', 'confidence': 1.0}], [{'entity': 'Endothelial cells', 'concept_id': 'C0225336', 'confidence': 1.0}, {'entity': 'enlarged', 'concept_id': 'C0442800', 'confidence': 1.0}, {'entity': 'plump', 'concept_id': 'C1836543', 'confidence': 0.7694027423858643}], [{'entity': 'Absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'differentiate', 'concept_id': 'C0205615', 'confidence': 0.9999998807907104}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'Kaposi sarcoma', 'concept_id': 'C0036220', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "758.0",
"width": "1920.0",
"id": "test_822",
"caption_rating": "8"
},
{
"": "1008292",
"caption": "Small, round, isolated intradermal nevus is not typical of this type of cancer.",
"image_path": "udoW6VSqsm4_image_7087ff7c-e736-45d6-895a-e3ec54e79ddb.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['Located in a digital acral location.']",
"noisy_text": " You probably do, but you just forgot it temporarily. Aggressive digital papillary adenocarcinoma. Oh, yeah. Because that's in a digital acral location. You have to think about that. It's not usually a small, round, isolated mid-dermal papule like we see here. So I like your idea of possible metastatic lesion. And so in general, when you look at something that seems to be small and symmetrical and well circumscribed at low power, and then you go to a higher value case and say, you know, there's some",
"corrected_text": " You probably do, but you just forgot it temporarily. Aggressive digital papillary adenocarcinoma. Oh, yeah. Because that's in a digital acral location. You have to think about that. It's not usually a small, round, isolated mid-dermal papule like we see here. So I like your idea of possible metastatic lesion. And so in general, when you look at something that seems to be small and symmetrical and well circumscribed at low power, and then you go to a higher value case and say, you know, there's some",
"med_umls_ids": "[[{'entity': 'Aggressive digital papillary adenocarcinoma', 'concept_id': 'C1367789', 'confidence': 1.0}, {'entity': 'digital acral', 'concept_id': 'C0442015', 'confidence': 0.8231403231620789}, {'entity': 'location', 'concept_id': 'C0450429', 'confidence': 1.0}], [{'entity': 'Metastatic lesion', 'concept_id': 'C1513183', 'confidence': 1.0}], [{'entity': 'Small', 'concept_id': 'C0700321', 'confidence': 0.9999998807907104}, {'entity': 'round', 'concept_id': 'C0332490', 'confidence': 1.0}, {'entity': 'isolated', 'concept_id': 'C0205409', 'confidence': 1.0}, {'entity': 'intradermal nevus', 'concept_id': 'C0206737', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_823",
"caption_rating": "8"
},
{
"": "1008340",
"caption": "Increased melanin pigment and dendritic melanocytes within the epidermis.",
"image_path": "8S4LeiO6Bbk_image_e9947037-d23a-421e-a41c-750914e5a706.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['abnormal maturation of keratinocytes', 'hyperchromatic cells', 'melanin pigment', 'dendritic melanocytes', 'abnormal maturation of keratinocytes', 'hyperchromatic cells', 'melanin pigment', 'dendritic melanocytes', 'abnormal maturation of keratinocytes', 'hyperchromatic cells', 'melanin pigment', 'dendritic melanocytes']",
"noisy_text": " I think would be reasonable considerations. However, if we move to higher power and begin to study the epidermis a little bit more carefully we can see that there's clear-cut abnormal maturation here. We've got full thickness keratinocytic atypia with nucleic acid or pleomorphic and hyperchromatic. There is abnormal maturation with even abnormal hyperchromatic perikaratotic cells within the stratum corneum. There's an increased amount of melanin pigment pressed within the basal layer and we can see that we've got an increased amount of melanin pigment and even a few dendritic melanocytes within the epidermis and so what we've got here is an example of pigmented Bowen's disease or pigmented squamous cell carcinoma. One could see similar changes in lesions",
"corrected_text": " I think would be reasonable considerations. However, if we move to higher power and begin to study the epidermis a little bit more carefully we can see that there's clear-cut abnormal maturation of keratinocytes here. We've got full thickness keratinocytic atypia with nucleic acid or pleomorphic and hyperchromatic. There is abnormal maturation with even abnormal hyperchromatic parakeratotic cells within the stratum corneum. There's an increased amount of melanin pigment pressed within the basal layer and we can see that we've got an increased amount of melanin pigment and even a few dendritic melanocytes within the epidermis and so what we've got here is an example of pigmented Bowen 's disease's disease or pigmented squamous cell carcinoma. One could see similar changes in lesions",
"med_umls_ids": "[[{'entity': 'Abnormal', 'concept_id': 'C0205161', 'confidence': 1.0}, {'entity': 'maturation', 'concept_id': 'C0678723', 'confidence': 1.0}, {'entity': 'keratinocytes', 'concept_id': 'C0022567', 'confidence': 1.0}, {'entity': 'thickness', 'concept_id': 'C1280412', 'confidence': 1.0}, {'entity': 'keratinocytic atypia', 'concept_id': 'C0741302', 'confidence': 0.6335055828094482}, {'entity': 'hyperchromatic cells', 'concept_id': 'C0333911', 'confidence': 0.823300302028656}, {'entity': 'stratum corneum', 'concept_id': 'C0221921', 'confidence': 1.0}], [{'entity': 'Increased', 'concept_id': 'C0205217', 'confidence': 1.0}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}, {'entity': 'pigment', 'concept_id': 'C0031911', 'confidence': 1.0}, {'entity': 'dendritic melanocytes', 'concept_id': 'C0025201', 'confidence': 0.7694142460823059}, {'entity': 'epidermis', 'concept_id': 'C0014520', 'confidence': 1.0}], [{'entity': 'Diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'Bowen\u2019s disease', 'concept_id': 'C0006079', 'confidence': 0.9730859994888306}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'squamous cell carcinoma', 'concept_id': 'C0007137', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_824",
"caption_rating": "8"
},
{
"": "1005602",
"caption": "Suspicion of the tumor coming from some other organ if not connected to the epidermis.",
"image_path": "udoW6VSqsm4_image_9e0a52df-aabf-4f95-91af-6da268169221.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " What neoplasms in the skin do have a myxoid stroma but also the glandular differentiation? PCCs can have... Sometimes they can, yeah. But this one was not connected to the epidermis in any way. No, not at all. And that raises suspicion like maybe this is coming from some other organ. Okay, a metastatic leaf can do that. Yeah, like breast or some... What part of the body are we on? We are acral. Yeah, we are acral. What is a glandular neoplasm in an acral site that can sometimes have a somewhat myxoid stroma? And their neoplasm in acral... I'm not",
"corrected_text": " What neoplasms in the skin do have a myxoid stroma but also the glandular differentiation? PCCs can have... Sometimes they can, yeah. But this one was not connected to the epidermis in any way. No, not at all. And that raises suspicion like maybe this is coming from some other organ. Okay, a metastatic leaf can do that. Yeah, like breast or some... What part of the body are we on? We are acral. Yeah, we are acral. What is a glandular neoplasm in an acral site that can sometimes have a somewhat myxoid stroma? And their neoplasm in acral... I'm not",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'myxoid stroma', 'concept_id': 'C1334857', 'confidence': 0.8506528735160828}, {'entity': 'glandular differentiation', 'concept_id': 'C1711212', 'confidence': 1.0}, {'entity': 'PCCs', 'concept_id': 'C1454906', 'confidence': 0.6863886713981628}], [{'entity': 'Suspicion', 'concept_id': 'C0242114', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'organ', 'concept_id': 'C0178784', 'confidence': 1.0}, {'entity': 'epidermis', 'concept_id': 'C0014520', 'confidence': 1.0}], [{'entity': 'Metastatic lesion', 'concept_id': 'C1513183', 'confidence': 1.0}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'breast', 'concept_id': 'C0006141', 'confidence': 1.0}, {'entity': 'organs', 'concept_id': 'C0178784', 'confidence': 1.0}], [{'entity': 'glandular neoplasms', 'concept_id': 'C0205854', 'confidence': 1.0}, {'entity': 'acral sites', 'concept_id': 'C0205145', 'confidence': 0.7343063950538635}, {'entity': 'myxoid stroma', 'concept_id': 'C1334857', 'confidence': 0.8506528735160828}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_825",
"caption_rating": "7"
},
{
"": "1004254",
"caption": "The appearance of a lesion can be misleading and resemble a benign keratosis, but it is important to check for orderly maturation to rule out squamous cell carcinoma.",
"image_path": "8S4LeiO6Bbk_image_7ccdc6bc-4c59-4185-a322-d10deafd6901.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['pigmented Bowen', 'interface dermatitis', 'punch biopsy', 'trunk or proximal']",
"noisy_text": " of these lesions that kind of is a fooler because it has a benign silhouette, resembles a psoriasis form dermatitis or even an inflamed pigmented seborrheic keratosis but it always behooves you to go down and check to make sure that you've got orderly maturation because architecturally Bowen's disease can resemble a benign keratosis. So, pigmented Bowen's disease in this case. Moving on to slide number eight. Slide number eight is the first of two interface dermatitis that we're going to be looking at. This is a bisected punch biopsy from the trunk or proximal extremity. Get",
"corrected_text": " of these lesions that kind of is a fooler because it has a benign silhouette, resembles a psoriasis form dermatitis or even an inflamed pigmented seborrheic keratosis but it always behooves you to go down and check to make sure that you've got orderly maturation because architecturally Bowen's disease can resemble a benign keratosis. So, pigmented Bowen 's disease's disease in this case. Moving on to slide number eight. Slide number eight is the first of two interface dermatitis that we're going to be looking at. This is a punch biopsy from the trunk or proximal extremity. Get",
"med_umls_ids": "[[{'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'misleading', 'concept_id': 'C0439049', 'confidence': 0.7600560784339905}, {'entity': 'benign keratosis', 'concept_id': 'C0334014', 'confidence': 0.7782552242279053}, {'entity': 'maturation', 'concept_id': 'C0678723', 'confidence': 1.0}, {'entity': 'squamous cell carcinoma', 'concept_id': 'C0007137', 'confidence': 1.0}], [{'entity': 'Slide number', 'concept_id': 'C3828004', 'confidence': 0.8261933326721191}, {'entity': 'punch biopsy', 'concept_id': 'C0182557', 'confidence': 1.0}, {'entity': 'trunk', 'concept_id': 'C0225442', 'confidence': 0.9999999403953552}, {'entity': 'proximal', 'concept_id': 'C0205107', 'confidence': 0.9999999403953552}, {'entity': 'interface dermatitis', 'concept_id': 'C0262981', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_826",
"caption_rating": "8"
},
{
"": "1007285",
"caption": "The presence of darker staining cells at the periphery, along with lymphocytes and scattered plasma cells, suggests the presence of infected histiocytes with small organisms within their cytoplasm.",
"image_path": "hoV-JkD6Wb0_image_255bd45b-c290-43f1-bcd7-9a28cf1ef870.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['Darker staining cells at the periphery', 'Organisms present within the cytoplasm of histiocytes']",
"noisy_text": " darker staining cells out at the periphery. And out at the periphery, we have a lot of lymphocytes and several scattered plasma cells. And if we look at the more clear staining areas, we can see that we actually have very large histiocytes. We've cleared out cytoplasm and with a little effort, one could see that there were organisms present within the cytoplasm of these histiocytes producing so-called parasitized histiocytes. And the organisms are very small, one to two microns. And we can use our erythrocyte here as kind of a ruler. Most erythrocytes and lymphocytes have nuclei that have diameters about five to six microns. And so you can see that these round organisms at",
"corrected_text": " darker staining cells out at the periphery. And out at the periphery, we have a lot of lymphocytes and several scattered plasma cells. And if we look at the more clear staining areas, we can see that we actually have very large histiocytes. We've cleared out cytoplasm and with a little effort, one could see that there were organisms present within the cytoplasm of these histiocytes producing so-called parasitized histiocytes. And the organisms are very small, one to two microns. And we can use our erythrocyte here as kind of a ruler. Most erythrocytes and lymphocytes have nuclei that have diameters about five to six microns. And so you can see that these round organisms at",
"med_umls_ids": "[[{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'darker staining cells', 'concept_id': 'C0007600', 'confidence': 0.5783368945121765}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'scattered', 'concept_id': 'C0439742', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'infected', 'concept_id': 'C0439663', 'confidence': 1.0}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'small organisms', 'concept_id': 'C0029235', 'confidence': 0.8106848001480103}, {'entity': 'cytoplasm', 'concept_id': 'C0010834', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "758.0",
"width": "1920.0",
"id": "test_827",
"caption_rating": "9"
},
{
"": "1004342",
"caption": "The biopsy specimen shows a hyperplastic epidermis that is papillary with an inflammatory infiltrate and several discrete cornoid lamella formation.",
"image_path": "8S4LeiO6Bbk_image_9ceb5416-9bcf-4224-85d1-aca7eb1a5922.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Vertical column of parakeratosis with underlying dyskeratotic cells in the stratum corneum and an absent granule layer (cornoid lamella)', 'Vertical column of parakeratosis with underlying dyskeratotic cells in the stratum corneum and an absent granule layer (cornoid lamella)']",
"noisy_text": " cells and also if we look in the dermal papillae between these zones, there are really no identifiable foam cells present within the dermal papillae. Looking over at the far edge of this lesion however, we can see that we've got this vertical column of pericaratosis with underlying dyskeratotic cells in the stratum corneum and an absent granule layer and this is very characteristic and meets all the criteria for a cornoid lamella. So we have this hyperplastic epidermis that is papillated with an inflammatory infiltrate and several discrete cornoid lamella formation across the biopsy specimen and this constellation of features is very characteristic of a variant of porocaratosis that tends to produce papules and at times very large plaques in",
"corrected_text": " cells and also if we look in the papillary dermis between these zones, there are really no identifiable foam cells present within the papillary dermis. Looking over at the far edge of this lesion however, we can see that we've got this vertical column of parakeratosis with underlying dyskeratotic cells in the stratum corneum and an absent granule layer and this is very characteristic and meets all the criteria for a cornoid lamella. So we have this hyperplastic epidermis that is papillary with an inflammatory infiltrate and several discrete cornoid lamella formation across the biopsy specimen and this constellation of features is very characteristic of a variant of porokeratosis that tends to produce papules and at times very large plaques in",
"med_umls_ids": "[[{'entity': 'biopsy specimen', 'concept_id': 'C0677862', 'confidence': 1.0}, {'entity': 'hyperplastic epidermis', 'concept_id': 'C4748317', 'confidence': 0.7633129358291626}, {'entity': 'papillary', 'concept_id': 'C0205312', 'confidence': 1.0}, {'entity': 'inflammatory infiltrate', 'concept_id': 'C3887644', 'confidence': 0.9999999403953552}, {'entity': 'discrete cornoid lamella formation', 'concept_id': 'C3552548', 'confidence': 0.7204381823539734}], [{'entity': 'constellation', 'concept_id': 'C5227392', 'confidence': 0.6721397042274475}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'variant', 'concept_id': 'C0205419', 'confidence': 1.0}, {'entity': 'porokeratosis', 'concept_id': 'C0162839', 'confidence': 1.0}, {'entity': 'papules', 'concept_id': 'C0332563', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_828",
"caption_rating": "9"
},
{
"": "1007973",
"caption": "Presence of lymphocytes and plasma cells is not a feature of chronicity, but architectural changes in gland size, shape, and distribution indicate chronicity.",
"image_path": "r7OA0Trj5hQ_image_0c7f536b-7466-42d1-bbd7-da3aff325ad0.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Neutrophils in the epithelium indicating cryptitis', 'Gastric biopsy for H. pylori with crypt abscess', 'Gastric biopsy for H. pylori with crypt abscess']",
"noisy_text": " Please remember, presence of lymphocytes and plasma cells is not a feature of chronicity. But architectural change by the way of irregular size, shape, and distributed glands is an indication of chronicity. Criteria for chronicity. Yeah, you see nicely neutrophils sitting in the epithelium. Can you all see neutrophils sitting in the epithelium? So this is cryptitis. It is stomach, even though I'm using the term. But I just want to know whether you are able to understand or not. This is a gastric biopsy where you have to look for H. pylori because the H. pylori secrete some chemotactic factors for neutrophils. That's why the neutrophils come. And this is a crypt abscess. This is",
"corrected_text": " Please remember, presence of lymphocytes and plasma cells is not a feature of chronicity. But architectural change by the way of irregular size, shape, and distributed glands is an indication of chronicity. Criteria for chronicity. Yeah, you see nicely neutrophils sitting in the epithelium. Can you all see neutrophils sitting in the epithelium? So this is cryptitis. It is stomach, even though I'm using the term. But I just want to know whether you are able to understand or not. This is a gastric biopsy where you have to look for H. pylori because the H. pylori secrete some chemotactic factors for neutrophils. That's why the neutrophils come. And this is a crypt abscess. This is",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'chronicity', 'concept_id': 'C0547045', 'confidence': 1.0}, {'entity': 'architectural', 'concept_id': 'C0003737', 'confidence': 0.8758222460746765}, {'entity': 'changes', 'concept_id': 'C0392747', 'confidence': 1.0}, {'entity': 'gland size', 'concept_id': 'C0426336', 'confidence': 0.8790121674537659}, {'entity': 'shape', 'concept_id': 'C0332479', 'confidence': 1.0}, {'entity': 'distribution', 'concept_id': 'C0037775', 'confidence': 1.0}, {'entity': 'chronicity', 'concept_id': 'C0547045', 'confidence': 1.0}], [{'entity': 'Neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'cryptitis', 'concept_id': 'C1394254', 'confidence': 0.9999998807907104}, {'entity': 'H. pylori infection', 'concept_id': 'C0850666', 'confidence': 0.9999999403953552}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_829",
"caption_rating": "9"
},
{
"": "1006496",
"caption": "Ganglion cells are also important in the diagnosis of congenital megacolon.",
"image_path": "r7OA0Trj5hQ_image_7d63d98a-cafd-4ea1-982a-8df59db88ce8.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['neural hypertrophy', 'ganglion cells', 'submucosa', 'congenital megacolon', 'neural hypertrophy', 'ganglion cells', 'submucosa', 'congenital megacolon']",
"noisy_text": " for example, carotid endoartrectomy or abdominal aortic encephalopathy, that history is very important for cholesterol emboli. Here, there is more like a neural hypertrophy. Whenever you see neural hypertrophy, you have to think of Crohn's disease. Here, you see the ganglion cells in the submicosa. When you see ganglion cells, these are normal component of the submicosa. And why I am showing it, sometimes you may think of malignancy. Here, you may not think of it. And another point, these are all the cells we are looking in congenital mecagola. So if you don't see them in the submicosa in frozen section, again, this will qualify for congenital mecagola. Here, another tricky thing. This is",
"corrected_text": " for example, carotid endarterectomy or abdominal aortic encephalopathy, that history is very important for cholesterol emboli. Here, there is more like a neural hypertrophy. Whenever you see neural hypertrophy, you have to think of Crohn's disease. Here, you see the ganglion cells in the submucosa. When you see ganglion cells, these are normal component of the submucosa. And why I am showing it, sometimes you may think of malignancy. Here, you may not think of it. And another point, these are all the cells we are looking in congenital megacolon. So if you don't see them in the submucosa in frozen section, again, this will qualify for congenital megacolon. Here, another tricky thing. This is",
"med_umls_ids": "[[{'entity': 'History', 'concept_id': 'C0019664', 'confidence': 1.0}, {'entity': 'carotid endarterectomy', 'concept_id': 'C0014099', 'confidence': 1.0}, {'entity': 'abdominal aortic encephalopathy', 'concept_id': 'C0507867', 'confidence': 0.6308470964431763}, {'entity': 'cholesterol emboli', 'concept_id': 'C0149649', 'confidence': 0.8653062582015991}], [{'entity': 'Neural hypertrophy', 'concept_id': 'C0020564', 'confidence': 0.8345715999603271}, {'entity': \"Crohn's disease\", 'concept_id': 'C0010346', 'confidence': 1.0}], [{'entity': 'Ganglion cells', 'concept_id': 'C0228071', 'confidence': 1.0}, {'entity': 'submucosa', 'concept_id': 'C0225344', 'confidence': 1.0}, {'entity': 'malignancy', 'concept_id': 'C0006826', 'confidence': 1.0}], [{'entity': 'Ganglion cells', 'concept_id': 'C0228071', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'congenital megacolon', 'concept_id': 'C0019569', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_830",
"caption_rating": "8"
},
{
"": "1007983",
"caption": "Infected histiocytes with organisms of this size in the cytoplasm may indicate histoplasmosis or leishmaniasis.",
"image_path": "hoV-JkD6Wb0_image_ea64ba0e-0739-4808-8bc0-2186caddb7f0.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['round organisms', 'histiocytes', 'infected histiocytes', 'organisms of this size', 'cytoplasm', 'histoplasmosis', 'leishmaniasis', 'periphery of the cell', 'histiocytes', 'organisms of this size', 'cytoplasm', 'histoplasmosis', 'leishmaniasis']",
"noisy_text": " one to two microns. And we can use our erythrocyte here as kind of a ruler. Most erythrocytes and lymphocytes have nuclei that have diameters about five to six microns. And so you can see that these round organisms at the periphery of the histiocytes are about one to two microns. And as you'll see in a subsequent slide, when you see parasitized histiocytes with organisms of this size in the cytoplasm, you're either dealing with histoplasmosis or leishmaniasis. And of the two, leishmaniasis has a tendency to cluster at the periphery of the cell producing the so-called marquee sign",
"corrected_text": " one to two microns. And we can use our erythrocyte here as kind of a ruler. Most erythrocytes and lymphocytes have nuclei that have diameters about five to six microns. And so you can see that these round organisms at the periphery of the histiocytes are about one to two microns. And as you'll see in a subsequent slide, when you see infected histiocytes with organisms of this size in the cytoplasm, you're either dealing with histoplasmosis or leishmaniasis. And of the two, leishmaniasis has a tendency to cluster at the periphery of the cell producing the socalled marquee sign",
"med_umls_ids": "[[{'entity': 'Round organisms', 'concept_id': 'C0029235', 'confidence': 0.813967227935791}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'microns', 'concept_id': 'C0439201', 'confidence': 0.9999999403953552}, {'entity': 'diameter', 'concept_id': 'C1301886', 'confidence': 1.0}], [{'entity': 'Infected', 'concept_id': 'C0439663', 'confidence': 1.0}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'organisms', 'concept_id': 'C0029235', 'confidence': 0.9999998807907104}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'cytoplasm', 'concept_id': 'C0010834', 'confidence': 1.0}, {'entity': 'histoplasmosis', 'concept_id': 'C0019655', 'confidence': 1.0}, {'entity': 'leishmaniasis', 'concept_id': 'C0023281', 'confidence': 1.0}], [{'entity': 'Leishmaniasis', 'concept_id': 'C0023281', 'confidence': 1.0}, {'entity': 'cluster', 'concept_id': 'C1555715', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'cell', 'concept_id': 'C0007634', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_831",
"caption_rating": "9"
},
{
"": "1009098",
"caption": "The glands seen in the image are pyloric gland metaplasia, which can be seen in colitis, end-associated injury, and mycophenol-associated injury.",
"image_path": "sDFjOtMAYrk_image_fdc63c33-230e-490f-9844-45f92c696e15.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['pyloric gland metaplasia', 'solid organ transplant recipient', 'eosinophils', 'pyloric gland metaplasia', 'solid organ transplant recipient', 'eosinophils']",
"noisy_text": " Yeah, these cells, these glands right here. What is it? Yeah, exactly. It's a pyloric glomeruloplasia. So pyloric glomeruloplasia should be Crohn's. No, you can see pyloric glomeruloplasia in your sort of a colitis and end-associated injury and also in microphenol-associated injury, as this case is. And the tip of the patient is a solid organ transplant recipient. with microphenol-associated injury have many more in the way of eosinophils, a lot more in the way of eosinophils than GVHD patients do. So that's really, really helpful. Is there",
"corrected_text": " Yeah, these cells, these glands right here. What is it? Yeah, exactly. It's a pyloric gland metaplasia. So pyloric gland metaplasia should be Crohn's. No, you can see pyloric gland metaplasia in your sort of a colitis and end-associated injury and also in mycophenol-associated injury, as this case is. And the tip of the patient is a solid organ transplant recipient. with mycophenol-associated injury have many more in the way of eosinophils, a lot more in the way of eosinophils than GVHD patients do. So that's really, really helpful. Is there",
"med_umls_ids": "[[{'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'image', 'concept_id': 'C1696103', 'confidence': 1.0}, {'entity': 'pyloric gland metaplasia', 'concept_id': 'C4288813', 'confidence': 1.0}, {'entity': 'colitis', 'concept_id': 'C0009319', 'confidence': 1.0}, {'entity': 'end-associated injury', 'concept_id': 'C0552509', 'confidence': 0.6716579794883728}, {'entity': 'mycophenol-associated injury', 'concept_id': 'C0552509', 'confidence': 0.6023857593536377}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'solid organ transplant', 'concept_id': 'C0730400', 'confidence': 1.0}, {'entity': 'recipient', 'concept_id': 'C1709854', 'confidence': 1.0}, {'entity': 'mycophenol-associated injury', 'concept_id': 'C0552509', 'confidence': 0.6023857593536377}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'GVHD', 'concept_id': 'C0018133', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_832",
"caption_rating": "9"
},
{
"": "1005985",
"caption": "Histopathological description of a targetoid hemosiderotic hemangioma, which can be distinguished from Kaposi\u2019s sarcoma by the absence of plasma cells within the infiltrate and negative HHV8 stain.",
"image_path": "8S4LeiO6Bbk_image_5750d535-b90e-4a34-bb16-2c47c6108757.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['collagen bundles', 'pre-existing vascular spaces', 'plump endothelial cells', 'absence of plasma cells', 'negative HHV8 stain']",
"noisy_text": " between collagen bundles. We even have a little bit of a promontory sign here where we've got these vessels surrounding pre-existing vascular spaces. But unlike the neovascular spaces that we see in Kaposi's sarcoma, the endothelial cells here are a little more plump, and we don't have plasma cells within the infiltrate. And plasma cells within the infiltrate can be very useful in discriminating between this condition and Kaposi's sarcoma. In this particular case, also the HHV8 stain was a negative, which would be positive in Kaposi's sarcoma. So the diagnosis in this case was a targetoid hemocidiotic hemangioma, sometimes known as a hobnail hemangioma. Frequently has a characteristic clinical appearance, occurs commonly",
"corrected_text": " between collagen bundles. We even have a little bit of a promontory sign here where we've got these vessels surrounding pre-existing vascular spaces. But unlike the neovascularization that we see in Kaposi's sarcoma, the endothelial cells here are a little more plump, and we don't have plasma cells within the infiltrate. And plasma cells within the infiltrate can be very useful in discriminating between this condition and Kaposi's sarcoma. In this particular case, also the HHV8 stain was a negative, which would be positive in Kaposi's sarcoma. So the diagnosis in this case was a targetoid hemosiderotic hemangioma, sometimes known as a hobnail hemangioma. Frequently has a characteristic clinical appearance, occurs commonly",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'targetoid hemosiderotic hemangioma', 'concept_id': 'C0346076', 'confidence': 0.9999999403953552}, {'entity': 'Kaposi\u2019s sarcoma', 'concept_id': 'C0036220', 'confidence': 0.9617650508880615}, {'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_833",
"caption_rating": "9"
},
{
"": "1007964",
"caption": "Presence of a vascular neoplasm with dilated endothelial line spaces and a biphasic pattern.",
"image_path": "8S4LeiO6Bbk_image_399c0607-b6b7-42ed-bfd8-639e0006c57b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['papillary projections', 'extravasated erythrocytes', 'dilated vessels', 'enlarged endothelial cells', 'collagen bundles', 'pre-existing vascular spaces', 'papillary projections', 'extravasated erythrocytes', 'dilated vessels', 'enlarged endothelial cells', 'collagen bundles', 'pre-existing vascular spaces']",
"noisy_text": " into the limina. If you look around, you can see these papillary projections. There are a few extravasated erythrocytes present within the stroma. So clearly, we've got this vascular neoplasma here with these dilated endothelial line spaces, but it's got kind of a bifasic pattern. Centrally, we've got these dilated vessels, but peripheral and beneath that zone, the vessels are somewhat more compressed. They're still lined by some of the plump endothelial cells. And in these various where the vessels are compressed, they kind of appear to dissect between collagen bundles. We even have a little bit of a promontory sign here where we've got these vessels surrounding pre-existing vascular spaces. But unlike the neovascular spaces that we see in Kaposi's sarcoma, the endothelial cells here are a little more plump, and we don't have plasma cells within the infiltrate. And plasma cells within the infiltrate can be very useful in discriminating between this condition and Kaposi's sarcoma. In this particular case, also the HHV8 stain was a negative, which",
"corrected_text": " into the limina. If you look around, you can see these papillary projections. There are a few extravasated erythrocytes present within the stroma. So clearly, we've got this vascular neoplasm here with these dilated endothelial line spaces, but it's got kind of a biphasic pattern. Centrally, we've got these dilated vessels, but peripheral and beneath that zone, the vessels are somewhat more compressed. They're still lined by some of the enlarged endothelial cells. And in these various where the vessels are compressed, they kind of appear to dissect between collagen bundles. We even have a little bit of a promontory sign here where we've got these vessels surrounding pre-existing vascular spaces. But unlike the neovascularization that we see in Kaposi's sarcoma, the endothelial cells here are a little more plump, and we don't have plasma cells within the infiltrate. And plasma cells within the infiltrate can be very useful in discriminating between this condition and Kaposi's sarcoma. In this particular case, also the HHV8 stain was a negative, which",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'vascular neoplasm', 'concept_id': 'C0027668', 'confidence': 1.0}, {'entity': 'dilated endothelial line spaces', 'concept_id': 'C0014257', 'confidence': 0.6450937390327454}, {'entity': 'biphasic pattern', 'concept_id': 'C1332555', 'confidence': 1.0}], [{'entity': 'Vessels', 'concept_id': 'C0005847', 'confidence': 1.0}, {'entity': 'peripheral', 'concept_id': 'C0205100', 'confidence': 1.0}, {'entity': 'central zone', 'concept_id': 'C0458698', 'confidence': 1.0}], [{'entity': 'Endothelial cells', 'concept_id': 'C0225336', 'confidence': 1.0}, {'entity': 'enlarged', 'concept_id': 'C0442800', 'confidence': 1.0}, {'entity': 'plump', 'concept_id': 'C1836543', 'confidence': 0.7694027423858643}], [{'entity': 'Absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'differentiate', 'concept_id': 'C0205615', 'confidence': 0.9999998807907104}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'Kaposi sarcoma', 'concept_id': 'C0036220', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "758.0",
"width": "1920.0",
"id": "test_834",
"caption_rating": "9"
},
{
"": "1006626",
"caption": "Presence of eosinophils in cytosis.",
"image_path": "sDFjOtMAYrk_image_e0850284-dc39-471f-9cff-c2943a16ca3f.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "[]",
"noisy_text": " cytosis that includes some eosinophils. So, the other trich I like to use, and I heard this from Dr. Appelman one time when he was lecturing, and he described crypt architecture in cases with inflammatory bowel disease, you no longer have that nice organized test tubes in a rack kind of architecture. The glands start to look like anything they want to look like. Rabbits, monkeys, the face of Jesus, whatever, except for test tubes on a rack. And the other thing is, sometimes you'll see them instead of growing down, they'll grow sideways. So, that's very apparent, very abnormal. So, I would say this is great evidence of chronicity, good architectural distortion. What other features besides architecture can you see in cases where there's some chronicity, albeit nonspecific findings? I mean, nothing is specific in chronic inflammatory colonic pathology,",
"corrected_text": " cytosis that includes some eosinophils. So, the other trich I like to use, and I heard this from Dr. Appelman one time when he was lecturing, and he described crypt architecture in cases with inflammatory bowel disease, you no longer have that nice organized tubular architecture. The glands start to look like anything they want to look like. Rabbits, monkeys, the face of Jesus, whatever, except for test tubes on a rack. And the other thing is, sometimes you'll see them instead of growing down, they'll grow sideways. So, that's very apparent, very abnormal. So, I would say this is great evidence of chronicity, good architectural distortion. What other features besides architecture can you see in cases where there's some chronicity, albeit nonspecific findings? I mean, nothing is specific in chronic inflammatory colonic pathology,",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'cytosis', 'concept_id': 'C0010843', 'confidence': 0.7890887260437012}], [{'entity': 'Inflammatory bowel disease', 'concept_id': 'C0021390', 'confidence': 1.0}, {'entity': 'loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'tubular', 'concept_id': 'C0151747', 'confidence': 1.0}, {'entity': 'architecture', 'concept_id': 'C0003737', 'confidence': 1.0}, {'entity': 'abnormal', 'concept_id': 'C0205161', 'confidence': 1.0}, {'entity': 'growth', 'concept_id': 'C0018270', 'confidence': 1.0}], [{'entity': 'Chronicity', 'concept_id': 'C0547045', 'confidence': 1.0}, {'entity': 'architectural distortion', 'concept_id': 'C2826609', 'confidence': 1.0}, {'entity': 'nonspecific', 'concept_id': 'C0750540', 'confidence': 1.0}, {'entity': 'findings', 'concept_id': 'C2607943', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_835",
"caption_rating": "7"
},
{
"": "1007650",
"caption": "Arabesque-type fibular material seen at the periphery of the fat microcysts.",
"image_path": "hoV-JkD6Wb0_image_ae24eba8-c8b9-412b-9009-f7ba4d5b0c4a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['Large fat microcysts', 'Membranous lipodystrophy at the periphery of the fat microcysts', 'Arabesque-type fibular material at the periphery of the fat microcysts', 'Remnant cell walls of adipocytes at the periphery of the fat microcysts', 'Large fat microcysts', 'Membranous lipodystrophy at the periphery of the fat microcysts', 'Arabesque-type fibular material at the periphery of the fat microcysts', 'Remnant cell walls of adipocytes at the periphery of the fat microcysts']",
"noisy_text": " inflammation. There aren't many viable adipocytes left here. A lot of the adipocytes have kind of ruptured and fused, and so we've got these large fat microcysts, and if we look at the periphery of the fat microcyst, we've got this lipomembranous change, this kind of arabesque-type fibular material out at the periphery, which basically represents coalescence of remnant cell walls of adipocytes. In addition, within the surrounding tissue, there's a little bit of fibrosis. There are a few lipophages and a very sparse infiltrative",
"corrected_text": " inflammation. There aren't many viable adipocytes left here. A lot of the adipocytes have kind of ruptured and fused, and so we've got these large fat microcysts, and if we look at the periphery of the fat microcyst, we've got this lipomembranous change, this kind of arabesque-type fibular material out at the periphery, which basically represents coalescence of remnant cell walls of adipocytes. In addition, within the surrounding tissue, there's a little bit of fibrosis. There are a few lipophages and a very sparse infiltrative",
"med_umls_ids": "[[{'entity': 'Inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}], [{'entity': 'adipocytes', 'concept_id': 'C0206131', 'confidence': 1.0}, {'entity': 'left', 'concept_id': 'C0205091', 'confidence': 1.0}], [{'entity': 'fat microcysts', 'concept_id': 'C1513269', 'confidence': 0.871767520904541}], [{'entity': 'Membranous lipodystrophy', 'concept_id': 'C0406599', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'fat microcysts', 'concept_id': 'C1513269', 'confidence': 0.871767520904541}], [{'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'fat microcysts', 'concept_id': 'C1513269', 'confidence': 0.871767520904541}], [{'entity': 'Coalescence', 'concept_id': 'C4727092', 'confidence': 0.8749340176582336}, {'entity': 'remnant', 'concept_id': 'C3272697', 'confidence': 1.0}, {'entity': 'cell walls', 'concept_id': 'C0007623', 'confidence': 1.0}, {'entity': 'adipocytes', 'concept_id': 'C0206131', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'fat microcysts', 'concept_id': 'C1513269', 'confidence': 0.871767520904541}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_836",
"caption_rating": "7"
},
{
"": "1008865",
"caption": "Increased melanin pigment and dendritic melanocytes within the epidermis.",
"image_path": "8S4LeiO6Bbk_image_e5790862-3f0c-49bc-bd05-fc6c6a29c969.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['abnormal maturation of keratinocytes', 'hyperchromatic cells', 'melanin pigment', 'dendritic melanocytes', 'abnormal maturation of keratinocytes', 'hyperchromatic cells', 'melanin pigment', 'dendritic melanocytes']",
"noisy_text": " I think would be reasonable considerations. However, if we move to higher power and begin to study the epidermis a little bit more carefully we can see that there's clear-cut abnormal maturation here. We've got full thickness keratinocytic atypia with nucleic acid or pleomorphic and hyperchromatic. There is abnormal maturation with even abnormal hyperchromatic perikaratotic cells within the stratum corneum. There's an increased amount of melanin pigment pressed within the basal layer and we can see that we've got an increased amount of melanin pigment and even a few dendritic melanocytes within the epidermis and so what we've got here is an example of pigmented Bowen's disease or pigmented squamous cell carcinoma. One could see similar changes in lesions",
"corrected_text": " I think would be reasonable considerations. However, if we move to higher power and begin to study the epidermis a little bit more carefully we can see that there's clear-cut abnormal maturation of keratinocytes here. We've got full thickness keratinocytic atypia with nucleic acid or pleomorphic and hyperchromatic. There is abnormal maturation with even abnormal hyperchromatic parakeratotic cells within the stratum corneum. There's an increased amount of melanin pigment pressed within the basal layer and we can see that we've got an increased amount of melanin pigment and even a few dendritic melanocytes within the epidermis and so what we've got here is an example of pigmented Bowen 's disease's disease or pigmented squamous cell carcinoma. One could see similar changes in lesions",
"med_umls_ids": "[[{'entity': 'Abnormal', 'concept_id': 'C0205161', 'confidence': 1.0}, {'entity': 'maturation', 'concept_id': 'C0678723', 'confidence': 1.0}, {'entity': 'keratinocytes', 'concept_id': 'C0022567', 'confidence': 1.0}, {'entity': 'thickness', 'concept_id': 'C1280412', 'confidence': 1.0}, {'entity': 'keratinocytic atypia', 'concept_id': 'C0741302', 'confidence': 0.6335055828094482}, {'entity': 'hyperchromatic cells', 'concept_id': 'C0333911', 'confidence': 0.823300302028656}, {'entity': 'stratum corneum', 'concept_id': 'C0221921', 'confidence': 1.0}], [{'entity': 'Increased', 'concept_id': 'C0205217', 'confidence': 1.0}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}, {'entity': 'pigment', 'concept_id': 'C0031911', 'confidence': 1.0}, {'entity': 'dendritic melanocytes', 'concept_id': 'C0025201', 'confidence': 0.7694142460823059}, {'entity': 'epidermis', 'concept_id': 'C0014520', 'confidence': 1.0}], [{'entity': 'Diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'Bowen\u2019s disease', 'concept_id': 'C0006079', 'confidence': 0.9730859994888306}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'squamous cell carcinoma', 'concept_id': 'C0007137', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_837",
"caption_rating": "9"
},
{
"": "1008377",
"caption": "The patient had a history of uveitis with characteristic features that were good for sarcoidosis.",
"image_path": "sDFjOtMAYrk_image_40f283f5-b3a7-423a-9bde-a1595d53e7ad.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['uveitis with characteristic features', 'granulomas in sarcoidosis and Crohn\u2019s disease', 'uveitis with characteristic features', 'granulomas in sarcoidosis and Crohn\u2019s disease']",
"noisy_text": " patient had sarcoid. So I said, this is probably not IBD, clinicians came down, we want to look at the biopsy, of course. It turns out that they went back and talked to the patient. The patient has a history of uveitis with characteristic features that were good for sarcoidosis. Nobody knew about they treated the patient for sarcoid, re-biopsied the patient. And he was fine. There were no more granulomas on multiple repeat biopsies. And now compare those grannies with the grannies in Crohn's. So here's a giant cell right there, but there was a better one right there. So they're like kind of",
"corrected_text": " patient had sarcoid. So I said, this is probably not IBD, clinicians came down, we want to look at the biopsy, of course. It turns out that they went back and talked to the patient. The patient has a history of uveitis with characteristic features that were good for sarcoidosis. Nobody knew about they treated the patient for sarcoid, re-biopsied the patient. And he was fine. There were no more granulomas on multiple repeat biopsies. And now compare those grannies with the grannies in Crohn's. So here's a giant cell right there, but there was a better one right there. So they're like kind of",
"med_umls_ids": "[[{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'suspected', 'concept_id': 'C0332147', 'confidence': 1.0}, {'entity': 'IBD', 'concept_id': 'C0021390', 'confidence': 1.0}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'history', 'concept_id': 'C0019664', 'confidence': 1.0}, {'entity': 'uveitis', 'concept_id': 'C0042164', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'treated', 'concept_id': 'C1522326', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'biopsies', 'concept_id': 'C0005558', 'confidence': 1.0}, {'entity': 'granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}], [{'entity': 'Comparison', 'concept_id': 'C1707455', 'confidence': 1.0}, {'entity': 'granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'Crohn\u2019s disease', 'concept_id': 'C0010346', 'confidence': 0.8916962146759033}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_838",
"caption_rating": "7"
},
{
"": "1004346",
"caption": "Poorly differentiated cells suggest high grade malignancy and possibly lymphoma.",
"image_path": "r7OA0Trj5hQ_image_e6327955-a8bf-4ccc-b799-cbf285df55ce.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['poorly differentiated cells', 'lamina propria', 'lymphoma', 'CD20 IHC positive', 'poorly differentiated cells', 'lamina propria', 'lymphoma', 'CD20 IHC positive']",
"noisy_text": " Here, what is happening? Very poorly differentiated cells, high grade malignancy. Again, definitely, it is proliferative disease with the ATP. Again, invasion metastasis, we cannot see from this picture. But whenever you see this much of poorly differentiated cells in the gastric biopsy or in the colonic biopsy, and predominantly the atypical cells are situated in the lamina propria, think of lymphoma. This is a CD20 IHC, strongly positive. So this is a non-Hodgkin's lymphoma, possibly diffuse large B cell type. So we are done with surface epithelium. We are done",
"corrected_text": " Here, what is happening? Very poorly differentiated cells, high grade malignancy. Again, definitely, it is proliferative disease with the ATP. Again, invasion metastasis, we cannot see from this picture. But whenever you see this much of poorly differentiated cells in the gastric biopsy or in the colonic biopsy, and predominantly the atypical cells are situated in the lamina propria, think of lymphoma. This is a CD20 IHC, strongly positive. So this is a non-Hodgkin's lymphoma, possibly diffuse large B cell type. So we are done with surface epithelium. We are done",
"med_umls_ids": "[[{'entity': 'Poorly differentiated cells', 'concept_id': 'C0205617', 'confidence': 0.9036805629730225}, {'entity': 'lymphoma', 'concept_id': 'C0024299', 'confidence': 1.0}], [{'entity': 'CD20', 'concept_id': 'C1417326', 'confidence': 1.0}, {'entity': 'IHC', 'concept_id': 'C0021044', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'non-Hodgkin lymphoma', 'concept_id': 'C0024305', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_839",
"caption_rating": "9"
},
{
"": "1004904",
"caption": "Presence of collagen balls surrounded by spindle-shaped cells.",
"image_path": "8S4LeiO6Bbk_image_dc9707a0-14b9-4e6c-9d02-b18c978b5a35.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['spindle-shaped cells', 'spindle-shaped cells', 'collagen balls', 'spindle-shaped cells', 'lipophagic cells', 'ringed siderophages', 'pigmented histiocytes']",
"noisy_text": " these collagen balls that are being surrounded by cells that have a somewhat spindled shape. The nuclei are spindled over our fusiform and they're kind of wrapping around these collagen bundles. In this same area, we can begin to see some lipophagia. So we see these large histiocytes containing lipid. Some of them are multi-nucleated and some of these are actually ringed siderophages. So we see large multi-nucleated histiocytes with a ring of nuclei and they contain not only lipid vacuoles but hemocentaurant. And these are particularly common in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes",
"corrected_text": " these collagen balls that are being surrounded by cells that have a somewhat spindle-shaped. The nuclei are spindle-shaped over our fusiform and they're kind of wrapping around these collagen bundles. In this same area, we can begin to see some lipophagic. So we see these large histiocytes containing lipid. Some of them are multi-nucleated and some of these are actually ringed siderophages. So we see large multinucleated histiocytes with a ring of nuclei and they contain not only lipid vacuoles but hemosiderin. And these are particularly common in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'collagen balls', 'concept_id': 'C0009325', 'confidence': 0.7217866778373718}, {'entity': 'surrounded', 'concept_id': 'C1282914', 'confidence': 1.0}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}], [{'entity': 'Lipophagic cells', 'concept_id': 'C0007584', 'confidence': 0.5962335467338562}, {'entity': 'lipid vacuoles', 'concept_id': 'C1179126', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'ringed', 'concept_id': 'C0325501', 'confidence': 0.77345871925354}, {'entity': 'siderophages', 'concept_id': 'C1136253', 'confidence': 0.7251443266868591}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_840",
"caption_rating": "7"
},
{
"": "1005268",
"caption": "Intraluminal proliferation of epithelium is an important criteria for high-grade dysplasia, which is characterized by loss of cellular polarity, nuclei reaching the surface, prominent nuclei, and cribriform and micropapillary patterns. The concept of dysplasia includes low-grade dysplasia.",
"image_path": "r7OA0Trj5hQ_image_7fa7d364-aa53-4c5c-919d-1c9e084f241a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Nuclei reaching the surface', 'Nuclei reaching the surface', 'Nuclei reaching the surface']",
"noisy_text": " and connecting the other side of the lumen. So the intra-glandular proliferation of the epithelium is very, very important criteria, which we call it as cribriformic for high-grade dysplasia. So this is a picture of high-grade dysplasia. And the criteria are loss of polarity, nuclei reaching the surface. Here you can see nuclei reaching the surface. Prominent nuclei, if you see carefully for 10 seconds, you can start seeing the nuclei and cribriformic and micropapillary. This concept of dysplasia, low-grade dysplasia and high-grade",
"corrected_text": " and connecting the other side of the lumen. So the intra-glandular proliferation of the epithelium is very, very important criteria, which we call it as cribriform for high-grade dysplasia. So this is a picture of high-grade dysplasia. And the criteria are loss of polarity, nuclei reaching the surface. Here you can see nuclei reaching the surface. Prominent nuclei, if you see carefully for 10 seconds, you can start seeing the nuclei and cribriform and micropapillary. This concept of dysplasia, low-grade dysplasia and high-grade",
"med_umls_ids": "[[{'entity': 'Intraluminal proliferation', 'concept_id': 'C0334094', 'confidence': 0.7116578221321106}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'criteria', 'concept_id': 'C0243161', 'confidence': 0.9999998807907104}, {'entity': 'high-grade dysplasia', 'concept_id': 'C1333110', 'confidence': 0.8831341862678528}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'cellular polarity', 'concept_id': 'C0085304', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'cribriform', 'concept_id': 'C1621425', 'confidence': 0.9999999403953552}, {'entity': 'micropapillary', 'concept_id': 'C1290608', 'confidence': 0.891559898853302}, {'entity': 'concept', 'concept_id': 'C0178566', 'confidence': 1.0}, {'entity': 'dysplasia', 'concept_id': 'C0334044', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'dysplasia', 'concept_id': 'C0334044', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_841",
"caption_rating": "9"
},
{
"": "1007915",
"caption": "The presence of numerous melanocytes in the matrix layer is highly suspicious for melanoma in situ.",
"image_path": "8S4LeiO6Bbk_image_d5b1b003-cbe4-408e-815b-f0a4aa81b2b9.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['nail bed', 'matrix epithelium', 'melanocytes forming nests', 'pagetoid pattern', 'basal layer of the matrix', 'upper portions of the matrix', 'nail bed', 'matrix epithelium', 'melanocytes forming nests', 'pagetoid pattern', 'basal layer of the matrix', 'upper portions of the matrix']",
"noisy_text": " we've got nail bed and matricle epithelium. I believe this must be some nail fold, a portion of the nail fold, and then in the bottom piece of tissue in these sections we actually have matricle epithelium and you can see the rete or somewhat hyperplastic. And on higher power examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matricle epithelium in the matricle layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that",
"corrected_text": " we've got nail bed and matrix epithelium. I believe this must be some nail fold, a portion of the nail fold, and then in the bottom piece of tissue in these sections we actually have matrix epithelium and you can see the rete or somewhat hyperplastic. And on higher power examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matrix epithelium in the matrix layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that",
"med_umls_ids": "[[{'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'sample', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'nail', 'concept_id': 'C0027342', 'confidence': 1.0}, {'entity': 'matrix epithelium', 'concept_id': 'C0014609', 'confidence': 0.7584323883056641}], [{'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'nests', 'concept_id': 'C0035253', 'confidence': 0.7275967001914978}, {'entity': 'upper portions', 'concept_id': 'C0449719', 'confidence': 0.6251541972160339}, {'entity': 'matrix', 'concept_id': 'C0331858', 'confidence': 1.0}, {'entity': 'pagetoid', 'concept_id': 'C1518847', 'confidence': 0.8801172375679016}, {'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}], [{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'matrix layer', 'concept_id': 'C0331858', 'confidence': 0.71736741065979}, {'entity': 'suspicious', 'concept_id': 'C0750493', 'confidence': 1.0}, {'entity': 'melanoma', 'concept_id': 'C0025202', 'confidence': 1.0}, {'entity': 'in situ', 'concept_id': 'C0444498', 'confidence': 0.9999999403953552}]]",
"magnification": "1.0",
"height": "758.0",
"width": "1920.0",
"id": "test_842",
"caption_rating": "9"
},
{
"": "1008935",
"caption": "Muscularization of the lamina propria in gastric mucosa may indicate chemical gastritis, which can be caused by biliary reflux or NSAID use.",
"image_path": "r7OA0Trj5hQ_image_75b89890-3f6b-4df3-a664-1f7ee3c87a05.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['muscularization of the lamina propria', 'gastric mucosa', 'chemical gastritis', 'antral biopsy', 'inflammation', 'muscularization of the lamina propria', 'gastric mucosa', 'chemical gastritis', 'antral biopsy', 'inflammation', 'muscularization of the lamina propria', 'gastric mucosa', 'chemical gastritis', 'antral biopsy', 'inflammation']",
"noisy_text": " and in cases of mucosal prolapse in colon. Remember that solitary rectal ulcer syndrome, which is totally misnomer. It is neither solitary, can be seen in other parts other than rectum. There may not be any ulcer, there is no syndrome. So the whole solitary rectal ulcer syndrome is a misnomer. But muscularization of the lamina propria is one of the criteria for mucosal prolapse that is happening in solitary rectal ulcer syndrome. And this is a gastric mucosa. Here when you see muscularization of the lamina propria, you have to think of chemical gastritis. Will it form surface changes? Lamina propria edema and muscularis mucosa coming into the lamina propria. These are the three criterias. When you see it in the anterobiopsy, think of chemical gastritis that can be seen in biliary reflux or NSAID use. Lot of inflammation results. Remember I",
"corrected_text": " and in cases of mucosal prolapse in colon. Remember that solitary rectal ulcer syndrome, which is totally misnomer. It is neither solitary, can be seen in other parts other than rectum. There may not be any ulcer, there is no syndrome. So the whole solitary rectal ulcer syndrome is a misnomer. But muscularization of the lamina propria is one of the criteria for mucosal prolapse that is happening in solitary rectal ulcer syndrome. And this is a gastric mucosa. Here when you see muscularization of the lamina propria, you have to think of chemical gastritis. Will it form surface changes? Lamina propria edema and muscularis mucosa coming into the lamina propria. These are the three criteria. When you see it in the endoscopic biopsy, think of chemical gastritis that can be seen in biliary reflux or NSAID use. Lot of inflammation results. Remember I",
"med_umls_ids": "[[{'entity': 'Muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'criterion', 'concept_id': 'C0243161', 'confidence': 1.0}, {'entity': 'mucosal prolapse', 'concept_id': 'C0034888', 'confidence': 0.826268196105957}, {'entity': 'colon', 'concept_id': 'C0009368', 'confidence': 1.0}, {'entity': 'solitary rectal ulcer syndrome', 'concept_id': 'C4274343', 'confidence': 0.9999999403953552}], [{'entity': 'Muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'gastric mucosa', 'concept_id': 'C0017136', 'confidence': 1.0}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}, {'entity': 'biliary reflux', 'concept_id': 'C0232483', 'confidence': 0.7931289672851562}, {'entity': 'NSAID', 'concept_id': 'C0003211', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_843",
"caption_rating": "9"
},
{
"": "1008608",
"caption": "Description of a large punch biopsy with an infiltrate filling the dermis and extending into the subcutaneous tissue.",
"image_path": "8S4LeiO6Bbk_image_6d184866-3f35-4310-ae66-fee18077910a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['infiltrate filling the dermis and extending into the subcutaneous tissue', 'brown pigment near the surface', 'hyperplastic epidermis', 'cellular infiltrate throughout the dermis', 'infiltrate filling the dermis and extending into the subcutaneous tissue', 'brown pigment near the surface', 'hyperplastic epidermis', 'cellular infiltrate throughout the dermis']",
"noisy_text": " a large punch biopsy. And I think this actually was two punch biopsies from one lesion, each one bisected. And we can see that we've got an infiltrate filling the dermis and extending into the subcutaneous tissue. The infiltrate appears to be compressing the fat rather than growing in between the adipocytes. And I think it's scanning magnification, you know, one of the things that you can really begin to appreciate, not only the fact that this lesion is partially sampled, that it extends to the base and edges of the specimen, but one can begin to appreciate abundant hemorrhage within this tumor. And in addition, we can see some brown pigment near the surface. And common sense will tell you where there's smoke, there's fire. Since we do have all this abundant hemorrhage, there's a high probability that the pigment, this brownish gold pigment that we're seeing up near the surface of the specimen is likely hemocentaurant rather than melanin. But we'll confirm that when we go down to a higher power. As we move in, we can see that the epidermis is slightly hyperplastic. We've got this cellular infiltrate throughout the dermis and we'll need to go down and take a look at this infiltrate. It appears a little less dense at the",
"corrected_text": " a large punch biopsy. And I think this actually was two punch biopsies from one lesion, each one bisected. And we can see that we've got an infiltrate filling the dermis and extending into the subcutaneous tissue. The infiltrate appears to be compressing the fat rather than growing in between the adipocytes. And I think it's scanning magnification, you know, one of the things that you can really begin to appreciate, not only the fact that this lesion is partially sampled, that it extends to the base and edges of the specimen, but one can begin to appreciate abundant hemorrhage within this tumor. And in addition, we can see some brown pigment near the surface. And common sense will tell you where there's smoke, there's fire. Since we do have all this abundant hemorrhage, there's a high probability that the pigment, this brownish gold pigment that we're seeing up near the surface of the specimen is likely hemocentaurant rather than melanin. But we'confirm that when we go down to a higher power. As we move in, we can see that the epidermis is slightly hyperplastic. We've got this cellular infiltrate throughout the dermis and we'll need to go down and take a look at this infiltrate. It appears a little less dense at the",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'punch biopsy', 'concept_id': 'C0182557', 'confidence': 1.0}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'filling', 'concept_id': 'C0178866', 'confidence': 0.7777882218360901}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'subcutaneous tissue', 'concept_id': 'C0222331', 'confidence': 1.0}], [{'entity': 'Excessive', 'concept_id': 'C0442802', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'brown pigment near', 'concept_id': 'C4555503', 'confidence': 0.865685760974884}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}], [{'entity': 'hyperplastic epidermis', 'concept_id': 'C4748317', 'confidence': 0.7633129358291626}, {'entity': 'cellular infiltrate', 'concept_id': 'C1692321', 'confidence': 1.0}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_844",
"caption_rating": "8"
},
{
"": "1007771",
"caption": "Muscularization of the lamina propria in gastric mucosa may indicate chemical gastritis, which can be caused by biliary reflux or NSAID use.",
"image_path": "r7OA0Trj5hQ_image_f29d9f96-bd76-4216-bc52-b759ac8f6415.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['muscularization of the lamina propria', 'gastric mucosa', 'chemical gastritis', 'antral biopsy', 'inflammation', 'muscularization of the lamina propria', 'gastric mucosa', 'chemical gastritis', 'antral biopsy', 'inflammation']",
"noisy_text": " and in cases of mucosal prolapse in colon. Remember that solitary rectal ulcer syndrome, which is totally misnomer. It is neither solitary, can be seen in other parts other than rectum. There may not be any ulcer, there is no syndrome. So the whole solitary rectal ulcer syndrome is a misnomer. But muscularization of the lamina propria is one of the criteria for mucosal prolapse that is happening in solitary rectal ulcer syndrome. And this is a gastric mucosa. Here when you see muscularization of the lamina propria, you have to think of chemical gastritis. Will it form surface changes? Lamina propria edema and muscularis mucosa coming into the lamina propria. These are the three criterias. When you see it in the anterobiopsy, think of chemical gastritis that can be seen in biliary reflux or NSAID use. Lot of inflammation results. Remember I",
"corrected_text": " and in cases of mucosal prolapse in colon. Remember that solitary rectal ulcer syndrome, which is totally misnomer. It is neither solitary, can be seen in other parts other than rectum. There may not be any ulcer, there is no syndrome. So the whole solitary rectal ulcer syndrome is a misnomer. But muscularization of the lamina propria is one of the criteria for mucosal prolapse that is happening in solitary rectal ulcer syndrome. And this is a gastric mucosa. Here when you see muscularization of the lamina propria, you have to think of chemical gastritis. Will it form surface changes? Lamina propria edema and muscularis mucosa coming into the lamina propria. These are the three criteria. When you see it in the endoscopic biopsy, think of chemical gastritis that can be seen in biliary reflux or NSAID use. Lot of inflammation results. Remember I",
"med_umls_ids": "[[{'entity': 'Muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'criterion', 'concept_id': 'C0243161', 'confidence': 1.0}, {'entity': 'mucosal prolapse', 'concept_id': 'C0034888', 'confidence': 0.826268196105957}, {'entity': 'colon', 'concept_id': 'C0009368', 'confidence': 1.0}, {'entity': 'solitary rectal ulcer syndrome', 'concept_id': 'C4274343', 'confidence': 0.9999999403953552}], [{'entity': 'Muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'gastric mucosa', 'concept_id': 'C0017136', 'confidence': 1.0}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}, {'entity': 'biliary reflux', 'concept_id': 'C0232483', 'confidence': 0.7931289672851562}, {'entity': 'NSAID', 'concept_id': 'C0003211', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_845",
"caption_rating": "9"
},
{
"": "1009444",
"caption": "Stratification has started and mucin is less, but not lost.",
"image_path": "r7OA0Trj5hQ_image_89087849-ec8f-4550-8740-0151d00b6738.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " that is pathologic in this biopsy. And there is mitosis and apoptosis. Remember, these four criteria for dysplasia. See again here, stratification has started. But you see, mucin is less. It is, I won't say lost. It is less. And this stratified nuclei reach the middle third. They are not touching the upper top of the apical membrane. They are reaching the middle third predominantly. Okay, that is one important point. And other one is, look at this nuclei. They are all traveling in one direction. So the polarity is maintained. Okay, so those two points are very important. And the third one",
"corrected_text": " that is pathologic in this biopsy. And there is mitosis and apoptosis. Remember, these four criteria for dysplasia. See again here, stratification has started. But you see, mucin is less. It is, I won't say lost. It is less. And this stratified nuclei reach the middle third. They are not touching the upper top of the apical membrane. They are reaching the middle third predominantly. Okay, that is one important point. And other one is, look at this nuclei. They are all traveling in one direction. So the polarity is maintained. Okay, so those two points are very important. And the third one",
"med_umls_ids": "[[{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'pathologic', 'concept_id': 'C1521733', 'confidence': 1.0}, {'entity': 'mitosis', 'concept_id': 'C0026255', 'confidence': 0.9999998807907104}, {'entity': 'apoptosis', 'concept_id': 'C0162638', 'confidence': 1.0}], [{'entity': 'Stratification', 'concept_id': 'C1514983', 'confidence': 1.0}, {'entity': 'started', 'concept_id': 'C1272689', 'confidence': 0.9999999403953552}, {'entity': 'mucin', 'concept_id': 'C0026682', 'confidence': 1.0}], [{'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'middle', 'concept_id': 'C0227972', 'confidence': 1.0}, {'entity': 'polarity', 'concept_id': 'C0596963', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_846",
"caption_rating": "7"
},
{
"": "1006383",
"caption": "Pathologists must differentiate between fibrous and fibrous cellular crescents when analyzing crescents.",
"image_path": "WhnEXkBN4D8_image_ce6107a2-3c60-4280-86b2-8f83f49d17fa.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Renal', 'Hematopathology', 'Soft tissue']",
"roi_text": "['Peritoneal epithelial hyperpressure compressing the glomerulus', 'Compressed glomerulus forming a crescent', 'Peritoneal epithelial hyperpressure compressing the glomerulus', 'Compressed glomerulus forming a crescent']",
"noisy_text": " If you see this, these are nothing but your peritoneal epithelial hyperpressure coming and compressing the glomeruli. That's one, right? Now with this information, let's go and look at this glomeruli again. Look at this glomeruli. This is the capsule. Everything else is compressed. So can I call this a beautiful crescent? Yes. So as a pathologist, when you compare the crescent, you have to say whether it's a fibrous crescent or a fibrous cellular crescent because that also makes sense here. Here, I",
"corrected_text": " If you see this, these are nothing but your peritoneal epithelial hyperpressure coming and compressing the glomeruli. That's one, right? Now with this information, let's go and look at this glomeruli again. Look at this glomeruli. This is the capsule. Everything else is compressed. So can I call this a beautiful crescent? Yes. So as a pathologist, when you compare the crescent, you have to say whether it's a fibrous crescent or a fibrous cellular crescent because that also makes sense here. Here, I",
"med_umls_ids": "[[{'entity': 'Peritoneal', 'concept_id': 'C0031153', 'confidence': 1.0}, {'entity': 'epithelial hyperpressure', 'concept_id': 'C0014599', 'confidence': 0.6601702570915222}, {'entity': 'compress', 'concept_id': 'C0180053', 'confidence': 1.0}, {'entity': 'glomerulus', 'concept_id': 'C0022663', 'confidence': 1.0}, {'entity': 'formation', 'concept_id': 'C0220781', 'confidence': 1.0}, {'entity': 'crescent', 'concept_id': 'C0444628', 'confidence': 1.0}], [{'entity': 'Pathologists', 'concept_id': 'C0334866', 'confidence': 1.0}, {'entity': 'differentiate', 'concept_id': 'C0205615', 'confidence': 0.9999998807907104}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}, {'entity': 'crescents', 'concept_id': 'C0444628', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_847",
"caption_rating": "8"
},
{
"": "1004815",
"caption": "Histopathological description of an epithelial tumor with interconnected cords and strands.",
"image_path": "8S4LeiO6Bbk_image_a0d9ca4b-d2c9-43b5-be52-eea868bbd3fd.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['epithelial tumor', 'cytoplasm', 'vesicular chromatin pattern', 'lymphocytes', 'duct formation', 'epithelial tumor', 'cytoplasm', 'vesicular chromatin pattern', 'lymphocytes', 'duct formation']",
"noisy_text": " If we move to higher power, we can see that we're dealing with an epithelial rather than a mosaicable tumor. We've got interconnected cords and strands. We have somewhat of a ribiform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of the cells are round to oval. They're fairly large. These cells have some faint eosinophilic to pale gray cytoplasm, although this cytoplasm is kind of difficult to see. Some of these cells have an evenly dispersed or vesicular chromatin pattern, and other nuclei are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and",
"corrected_text": " If we move to higher power, we can see that we're dealing with an epithelial rather than a mesenchymal tumor. We've got interconnected cords and strands. We have somewhat of a cribriform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of the cells are round to oval. They're fairly large. These cells have some faint eosinophilic to pale gray cytoplasm, although this cytoplasm is kind of difficult to see. Some of these cells have an evenly dispersed or vesicular chromatin pattern, and other nuclei are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'epithelial tumor', 'concept_id': 'C1368683', 'confidence': 0.9999999403953552}, {'entity': 'cords', 'concept_id': 'C0034869', 'confidence': 0.801885187625885}, {'entity': 'strands', 'concept_id': 'C0600383', 'confidence': 0.800572395324707}], [{'entity': 'Cribriform pattern', 'concept_id': 'C1333163', 'confidence': 1.0}, {'entity': 'loose', 'concept_id': 'C0205407', 'confidence': 1.0}, {'entity': 'edematous', 'concept_id': 'C0013604', 'confidence': 1.0}, {'entity': 'vascular stroma', 'concept_id': 'C0005847', 'confidence': 0.8046398758888245}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'cell types', 'concept_id': 'C0007634', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'eosinophilic', 'concept_id': 'C0333930', 'confidence': 1.0}, {'entity': 'pale', 'concept_id': 'C0030232', 'confidence': 1.0}, {'entity': 'gray cytoplasm', 'concept_id': 'C0010834', 'confidence': 0.8177905678749084}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'duct', 'concept_id': 'C0687028', 'confidence': 1.0}, {'entity': 'formation', 'concept_id': 'C0220781', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_848",
"caption_rating": "8"
},
{
"": "1007059",
"caption": "Identification of the cell type responsible for producing protein fibers and ground substance in connective tissue.",
"image_path": "ib991vTA67A_image_5decb0dd-359e-469d-8efb-95f2607ea6e6.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Head and Neck']",
"roi_text": "['scattered little nuclei', 'scattered little nuclei', 'cell type making protein fibers and ground substance in connective tissue']",
"noisy_text": " So here's, here's, here's this one. So number sixteen, what is this Connective Tissue and tell me the name of the scattered little nuclei, we see the nuclei all throughout here. Most of these nuclei belong to what cell, that cell is making the protein fibers and the ground substance in this Connective Tissue. So what cell type is living in here that's making these protein fibers and the ground substance in this Connective Tissue? That was number sixteen. Here's this one, seeing it again, this one's not quite as clear, you can see the protein fibers here,",
"corrected_text": " So here's, here's, here's this one. So number sixteen, what is this Connective Tissue and tell me the name of the scattered little nuclei, we see the nuclei all throughout here. Most of these nuclei belong to what cell, that cell is making the protein fibers and the ground substance in this Connective Tissue. So what cell type is living in here that's making these protein fibers and the ground substance in this Connective Tissue? That was number sixteen. Here's this one, seeing it again, this one's not quite as clear, you can see the protein fibers here,",
"med_umls_ids": "[[{'entity': 'Identification', 'concept_id': 'C0020792', 'confidence': 1.0}, {'entity': 'cell type', 'concept_id': 'C0007634', 'confidence': 1.0}, {'entity': 'protein fibers', 'concept_id': 'C0000696', 'confidence': 0.7645217180252075}, {'entity': 'ground substance', 'concept_id': 'C1253945', 'confidence': 1.0}, {'entity': 'connective tissue', 'concept_id': 'C0009780', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1152.0",
"id": "test_849",
"caption_rating": "8"
},
{
"": "1007212",
"caption": "The cells around the edge of the rosettes tend to get more round and almost epithelioid, forming a perivascular pseudorosette.",
"image_path": "QDb68_G1HR4_image_306335b2-2cec-4f66-9a1e-830694a796bb.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Perivascular pseudorosette with cells clustering around the edge.']",
"noisy_text": " rosettes example and here this one actually this is basically a little rosette it's got a vessel in the middle but look what we're seeing here on the edge is what's described that you often see the other case didn't show it nicely but around the edge of the rosettes the cells tend to get more round and almost epithelioid and kind of cluster around the edge of the rosette so I think that's a really good example here of kind of a collagen rosette and the larger kind of more round but still very bland and monomorphic uniform cells that",
"corrected_text": " rosettes example and here this one actually this is basically a little rosette it's got a vessel in the middle but look what we're seeing here on the edge is what's described that you often see the other case didn't show it nicely but around the edge of the rosettes the cells tend to get more round and almost epithelioid and kind of cluster around the edge of the rosette so I think that's a really good example here of kind of a perivascular pseudorosette and the larger kind of more round but still very bland and monomorphic uniform cells that",
"med_umls_ids": "[[{'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'edge', 'concept_id': 'C0205154', 'confidence': 1.0}, {'entity': 'rosettes', 'concept_id': 'C0035863', 'confidence': 0.8847858905792236}, {'entity': 'round', 'concept_id': 'C0332490', 'confidence': 1.0}, {'entity': 'epithelioid', 'concept_id': 'C0014603', 'confidence': 0.8891293406486511}, {'entity': 'perivascular', 'concept_id': 'C0442165', 'confidence': 1.0}, {'entity': 'pseudorosette', 'concept_id': 'C1335569', 'confidence': 0.8461084365844727}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_850",
"caption_rating": "8"
},
{
"": "1005450",
"caption": "The concept of dysplasia, low-grade dysplasia, and high-grade dysplasia is essential and can be applied in various organs, including the pancreas, gallbladder, bile duct, breast, and prostate.",
"image_path": "r7OA0Trj5hQ_image_5434d6f7-8537-4fb9-91a7-bb9f399527fd.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " This concept of dysplasia, low-grade dysplasia and high-grade dysplasia is very, very essential because you can apply this criteria in any organ. You can apply it in the pancreas. You can apply it in the gallbladder. You can apply it in the bile duct. Even you can apply it in the breast. You can apply it in the prostate. You can apply it wherever you want. These are all in the GI tract known as adenomatous changes with the low-grade or high-grade dysplasia. In the other organs, it is known as dysplastic changes with the low-grade and the high-grade dysplasia. This is a beautiful picture I got it from the Google where it looks normal",
"corrected_text": " This concept of dysplasia, low-grade dysplasia and high-grade dysplasia is very, very essential because you can apply this criteria in any organ. You can apply it in the pancreas. You can apply it in the gallbladder. You can apply it in the bile duct. Even you can apply it in the breast. You can apply it in the prostate. You can apply it wherever you want. These are all in the GI tract known as adenomatous changes with the low-grade or high-grade dysplasia. In the other organs, it is known as dysplastic changes with the low-grade and the high-grade dysplasia. This is a beautiful picture I got it from the Google where it looks normal",
"med_umls_ids": "[[{'entity': 'concept', 'concept_id': 'C0178566', 'confidence': 1.0}, {'entity': 'dysplasia', 'concept_id': 'C0334044', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'dysplasia', 'concept_id': 'C0334044', 'confidence': 1.0}, {'entity': 'high-grade dysplasia', 'concept_id': 'C1333110', 'confidence': 0.8831341862678528}, {'entity': 'essential', 'concept_id': 'C0205224', 'confidence': 0.9999999403953552}, {'entity': 'organs', 'concept_id': 'C0178784', 'confidence': 1.0}, {'entity': 'pancreas', 'concept_id': 'C0030274', 'confidence': 0.9999999403953552}, {'entity': 'gallbladder', 'concept_id': 'C0016976', 'confidence': 0.9999999403953552}, {'entity': 'bile duct', 'concept_id': 'C0005400', 'confidence': 1.0}, {'entity': 'breast', 'concept_id': 'C0006141', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}], [{'entity': 'Adenomatous', 'concept_id': 'C0333981', 'confidence': 0.785536527633667}, {'entity': 'changes', 'concept_id': 'C0392747', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'high-grade dysplasia', 'concept_id': 'C1333110', 'confidence': 0.8831341862678528}, {'entity': 'GI tract', 'concept_id': 'C0017189', 'confidence': 1.0}, {'entity': 'dysplastic', 'concept_id': 'C0334044', 'confidence': 0.9999999403953552}, {'entity': 'changes', 'concept_id': 'C0392747', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'high-grade dysplasia', 'concept_id': 'C1333110', 'confidence': 0.8831341862678528}, {'entity': 'organs', 'concept_id': 'C0178784', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_851",
"caption_rating": "8"
},
{
"": "1006993",
"caption": "The tissue sample is not indicative of Crohn's disease due to preserved architecture and coalescing masses of granulomas that are expanding the lamina propria.",
"image_path": "sDFjOtMAYrk_image_350e8de4-ae29-411b-a9ce-6c4697d869d1.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['coalescing masses of granulomas', 'expanding the lamina propria', 'coalescing masses of granulomas', 'expanding the lamina propria', 'expanding the lamina propria']",
"noisy_text": " Crohn's. No. Why is it not Crohn's? So two main reasons why it's not Crohn's. So number one, the architecture is completely preserved. Okay. That can happen in Crohn's. Why not? The granulomas are too good to be true. You can have granulomas sometimes will form in Crohn's of course, rarely, but they won't be coalescing. They won't be expanding the lamina propria to this degree. So if you have coalescing masses of granulomas, quite romantic. I like this place. So if you have big coalescing masses of granuloma, expanding your lamina propria, think something other than Crohn's. Think of infectious process, especially if",
"corrected_text": " Crohn's. No. Why is it not Crohn's? So two main reasons why it's not Crohn's. So number one, the architecture is completely preserved. Okay. That can happen in Crohn's. Why not? The granulomas are too good to be true. You can have granulomas sometimes will form in Crohn's of course, rarely, but they won't be coalescing. They won't be expanding the lamina propria to this degree. So if you have coalescing masses of granulomas, quite romantic. I like this place. So if you have big coalescing masses of granuloma, expanding your lamina propria, think something other than Crohn's. Think of infectious process, especially if",
"med_umls_ids": "[[{'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': \"Crohn's disease\", 'concept_id': 'C0010346', 'confidence': 1.0}, {'entity': 'architecture', 'concept_id': 'C0003737', 'confidence': 1.0}, {'entity': 'coalescing masses', 'concept_id': 'C4727092', 'confidence': 0.5960795283317566}, {'entity': 'granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}], [{'entity': 'Infectious process', 'concept_id': 'C0745283', 'confidence': 1.0}, {'entity': 'Crohn\u2019s disease', 'concept_id': 'C0010346', 'confidence': 0.8916962146759033}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_852",
"caption_rating": "9"
},
{
"": "1009105",
"caption": "Presence of lymphocytes and hints of duct formation within the tumor.",
"image_path": "8S4LeiO6Bbk_image_1e8d3c8f-6507-4fdb-b5cf-6edd5afdfe9f.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['lymphocytes', 'epithelial tumor', 'cytoplasm', 'vesicular chromatin pattern', 'lymphocytes', 'duct formation', 'cytoplasm']",
"noisy_text": " If we move to higher power, we can see that we're dealing with an epithelial rather than a mosaicable tumor. We've got interconnected cords and strands. We have somewhat of a ribiform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of the cells are round to oval. They're fairly large. These cells have some faint eosinophilic to pale gray cytoplasm, although this cytoplasm is kind of difficult to see. Some of these cells have an evenly dispersed or vesicular chromatin pattern, and other nuclei are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and",
"corrected_text": " If we move to higher power, we can see that we're dealing with an epithelial rather than a mesenchymal tumor. We've got interconnected cords and strands. We have somewhat of a cribriform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of the cells are round to oval. They're fairly large. These cells have some faint eosinophilic to pale gray cytoplasm, although this cytoplasm is kind of difficult to see. Some of these cells have an evenly dispersed or vesicular chromatin pattern, and other nuclei are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'epithelial tumor', 'concept_id': 'C1368683', 'confidence': 0.9999999403953552}, {'entity': 'cords', 'concept_id': 'C0034869', 'confidence': 0.801885187625885}, {'entity': 'strands', 'concept_id': 'C0600383', 'confidence': 0.800572395324707}], [{'entity': 'Cribriform pattern', 'concept_id': 'C1333163', 'confidence': 1.0}, {'entity': 'loose', 'concept_id': 'C0205407', 'confidence': 1.0}, {'entity': 'edematous', 'concept_id': 'C0013604', 'confidence': 1.0}, {'entity': 'vascular stroma', 'concept_id': 'C0005847', 'confidence': 0.8046398758888245}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'cell types', 'concept_id': 'C0007634', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'eosinophilic', 'concept_id': 'C0333930', 'confidence': 1.0}, {'entity': 'pale', 'concept_id': 'C0030232', 'confidence': 1.0}, {'entity': 'gray cytoplasm', 'concept_id': 'C0010834', 'confidence': 0.8177905678749084}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'duct', 'concept_id': 'C0687028', 'confidence': 1.0}, {'entity': 'formation', 'concept_id': 'C0220781', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_853",
"caption_rating": "8"
},
{
"": "1007288",
"caption": "Syncytial-like surface epithelium with intrapithelial cells is present in another case.",
"image_path": "sDFjOtMAYrk_image_dbb55e5b-acbf-4660-9bc4-525721662a45.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['surface epithelial injury', 'superficial mucin', 'lamina propria', 'syncytial-like surface epithelium', 'intrapithelial cells']",
"noisy_text": " We just know what is normal and what too much is too much. Besides having that, the low power appearance, of course, will have a lack of significant architectural distortion. And you will see it will look a little bit blue. Where's my arrow? It will look somewhat blue at low power because there's loss of surface epithelial injury, loss of superficial mucin, and the lamina propria will be expanded. That's one case. And here's another, a little bit more of a dramatic appearance with really, really good syncytial-like looking surface epithelial with tons of intrapithelial lymphocytes and",
"corrected_text": " We just know what is normal and what too much is too much. Besides having that, the low power appearance, of course, will have a lack of significant architectural distortion. And you will see it will look a little bit blue. Where's my arrow? It will look somewhat blue at low power because there's loss of surface epithelial injury, loss of superficial mucin, and the lamina propria will be expanded. That's one case. And here's another, a little bit more of a dramatic appearance with really, really good syncytial-like looking surface epithelial with tons of intrapithelial lymphocytes and",
"med_umls_ids": "[[{'entity': 'Low', 'concept_id': 'C0205251', 'confidence': 0.9999999403953552}, {'entity': 'power', 'concept_id': 'C0032863', 'confidence': 1.0}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'normal tissue', 'concept_id': 'C0040300', 'confidence': 0.9999999403953552}, {'entity': 'lack', 'concept_id': 'C0332268', 'confidence': 1.0}, {'entity': 'architectural', 'concept_id': 'C0003737', 'confidence': 0.8758222460746765}], [{'entity': 'Loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'mucin', 'concept_id': 'C0026682', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'blue', 'concept_id': 'C1260957', 'confidence': 1.0}], [{'entity': 'Syncytial-like surface epithelium', 'concept_id': 'C1182809', 'confidence': 0.6702060103416443}, {'entity': 'intrapithelial cells', 'concept_id': 'C0014597', 'confidence': 0.7846651077270508}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_854",
"caption_rating": "8"
},
{
"": "1008170",
"caption": "A 44-year-old HIV-positive male with a bloody bowel movement and post-polio syndrome is being evaluated for IBD.",
"image_path": "sDFjOtMAYrk_image_122f8ebc-3fcb-439a-b433-34aad5db121d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['bloody bowel movement', 'IBD evaluation', 'architectural distortion', 'missing gland', 'bifurcation', 'crypt dropout', 'granulation tissue', 'crypt microabscesses', 'cryptitis', 'bloody bowel movement', 'IBD evaluation', 'architectural distortion', 'missing gland', 'bifurcation', 'crypt dropout', 'granulation tissue', 'crypt microabscesses', 'cryptitis']",
"noisy_text": " So moving along to number three, Hamar. Can you read the history please? Yeah. It's 44 years old HIV male with a bloody bowel movement and polio arthritis condition concerned about IBD. Okay. So are you gonna, are we gonna stamp him with IBD? Not yet. No, because we already saw IBD, right? So what would you say about the architectural distortion? So some sections, there's no distortion, but in some area we can see there's a lot of missing gland and the distortion of the maybe some bifurcation, right? Yeah. So some bifurcation, some crypt dropout, lots of granulation tissue, and we have plenty in the way of activity. Yeah. So I would say more than I'm used to seeing in this process. So good crypt micro abscesses and cryptitis. And then bear",
"corrected_text": " So moving along to number three, Hamar. Can you read the history please? Yeah. It's 44 years old HIV male with a bloody bowel movement and polio arthritis condition concerned about IBD. Okay. So are you gonna, are we gonna stamp him with IBD? Not yet. No, because we already saw IBD, right? So what would you say about the architectural distortion? So some sections, there's no distortion, but in some area we can see there's a lot of missing gland and the distortion of the maybe some bifurcation, right? Yeah. So some bifurcation, some crypt dropout, lots of granulation tissue, and we have plenty in the way of activity. Yeah. So I would say more than I'm used to seeing in this process. So good crypt micro abscesses and cryptitis. And then bear",
"med_umls_ids": "[[{'entity': 'HIV-positive', 'concept_id': 'C4287934', 'confidence': 0.6893086433410645}, {'entity': 'male', 'concept_id': 'C0086582', 'confidence': 1.0}, {'entity': 'bloody bowel movement', 'concept_id': 'C0151594', 'confidence': 0.9999998807907104}, {'entity': 'post-polio syndrome', 'concept_id': 'C0080040', 'confidence': 1.0}, {'entity': 'evaluated', 'concept_id': 'C0220825', 'confidence': 1.0}, {'entity': 'IBD', 'concept_id': 'C0021390', 'confidence': 1.0}], [{'entity': 'Architectural distortion', 'concept_id': 'C2826609', 'confidence': 1.0}, {'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'bifurcation', 'concept_id': 'C0184906', 'confidence': 0.9999999403953552}, {'entity': 'crypt', 'concept_id': 'C1880192', 'confidence': 1.0}, {'entity': 'dropout', 'concept_id': 'C0013135', 'confidence': 1.0}, {'entity': 'granulation tissue', 'concept_id': 'C0018180', 'confidence': 1.0}], [{'entity': 'Crypt', 'concept_id': 'C1880192', 'confidence': 1.0}, {'entity': 'microabscesses', 'concept_id': 'C0333373', 'confidence': 0.879554271697998}, {'entity': 'cryptitis', 'concept_id': 'C1394254', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_855",
"caption_rating": "8"
},
{
"": "1006804",
"caption": "Enlarged nuclei that are about six times the size of normal prostate nuclei.",
"image_path": "iklRyY1nBIE_image_06474144-5c48-46a7-8e65-c93b6249c886.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['basal cells at the periphery', 'enlarged nuclei', 'intraductal carcinoma of the prostate', 'adjacent invasive tumor', 'previously benign gland', 'basal cells at the periphery', 'enlarged nuclei', 'intraductal carcinoma of the prostate', 'adjacent invasive tumor', 'previously benign gland']",
"noisy_text": " Let me show you what the cocktail looks like. Again, this is the pin three, or some call it pin four. You have the P63, you have the hemoglobin cytokeratin, and then you have the racemase, which is the pink chromogen. And as you can see, as I demonstrated on the H&E, basal cells are indeed present. This is too much for high-grade pin. This is basically what is called a solid cribriform kind of pattern, in which over 50% of the lumen is filled by tumor cells. So this is way too much for high-grade pin. But it's not invasive, because you have basal cells at the periphery. And the nuclei are enlarged. These nuclei are about six times the size of normal prostate nuclei. So this case meets the criteria for introductal carcinoma of the prostate. There is an invasive component, which you can see is negative for basal cell markers. But you have the introductal component. And this is a very interesting entity. The vast majority of cases, and I'll show you the corresponding radical prostatectomy specimens in a second, but the vast majority of these so-called introductal carcinoma of the prostate is due to invasion, colonization by adjacent invasive tumor. And it usually occurs in patients that have high-volume tumors. When I show you the corresponding radical prostatectomies, you'll see what I'm talking about. You usually don't have this in patients in their radicals that have 5% prostate cancer or 10% prostate cancer. It's usually patients that have extensive prostate cancer involvement, and the invasive glands basically have nowhere else to go but to colonize adjacent benign glands. And I'll demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues,",
"corrected_text": " Let me show you what the cocktail looks like. Again, this is the pin three, or some call it pin four. You have the P63, you have the hemoglobin cytokeratin, and then you have the racemase, which is the AMACR. And as you can see, as I demonstrated on the H&E, basal cells are indeed present. This is too much for high-grade pin. This is basically what is called a solid cribriform kind of pattern, in which over 50% of the lumen is filled by tumor cells. So this is way too much for high-grade pin. But it's not invasive, because you have basal cells at the periphery. And the nuclei are enlarged. These nuclei are about six times the size of normal prostate nuclei. So this case meets the criteria for intraductal carcinoma of the prostate. There is an invasive component, which you can see is negative for basal cell markers. But you have the intraductal component. And this is a very interesting entity. The vast majority of cases, and I'll show you the corresponding radical prostatectomy specimens in a second, but the vast majority of these so-called intraductal carcinoma of the prostate is due to invasion, colonization by adjacent invasive tumor. And it usually occurs in patients that have high-volume tumors. When I show you the corresponding radical prostatectomies, you'll see what I'm talking about. You usually don't have this in patients in their radicals that have 5% prostate cancer or 10% prostate cancer. It's usually patients that have extensive prostate cancer involvement, and the invasive glands basically have nowhere else to go but to colonize adjacent benign glands. And I'demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues,",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'cocktail', 'concept_id': 'C0678420', 'confidence': 1.0}, {'entity': 'markers', 'concept_id': 'C0181734', 'confidence': 0.890313982963562}, {'entity': 'intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate diagnosis', 'concept_id': 'C0011900', 'confidence': 0.7927443981170654}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'basal cells', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}], [{'entity': 'Enlarged nuclei', 'concept_id': 'C4013177', 'confidence': 0.7774685621261597}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'normal', 'concept_id': 'C0205307', 'confidence': 1.0}], [{'entity': 'Intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'invasion', 'concept_id': 'C1269955', 'confidence': 1.0}, {'entity': 'colonization', 'concept_id': 'C4289767', 'confidence': 1.0}, {'entity': 'adjacent', 'concept_id': 'C0205117', 'confidence': 1.0}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}], [{'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'benign gland', 'concept_id': 'C0205183', 'confidence': 0.7986565828323364}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_856",
"caption_rating": "8"
},
{
"": "1009195",
"caption": "The tissue has myxoid features with very fine delicate collagen.",
"image_path": "QDb68_G1HR4_image_559a6539-9ae0-45d0-8273-a583aa8f043a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['myxoid features', 'fine delicate collagen', 'cellular intramuscular myxoma', 'fibrous areas', 'cellular areas', 'MUC4 stain']",
"noisy_text": " Here's again the myxoid background I really think this is very helpful. The very very fine delicate collagen that you see. Now areas like this I think can kind of resemble what you see in a so-called cellular intramuscular myxoma. Intramuscular myxomas are usually very blue and myxoid very hypocellular but sometimes they get more fibrous and more cellular areas. And on a needle biopsy I think that can be challenging. So I think usually with some experience you can tell them apart on H and E most of the time but when I have any doubt I just do a MUC4 stain. The MUC4 is negative and on a needle it looks like a myxoma with some kind of fibrous or a little bit more cellular areas and then I just say that it's probably a cellular intramuscular myxoma. So I think MUC4",
"corrected_text": " Here's again the myxoid background I really think this is very helpful. The very very fine delicate collagen that you see. Now areas like this I think can kind of resemble what you see in a so-called cellular intramuscular myxoma. Intramuscular myxomas are usually very blue and myxoid very hypocellular but sometimes they get more fibrous and more cellular areas. And on a needle biopsy I think that can be challenging. So I think usually with some experience you can tell them apart on H and E most of the time but when I have any doubt I just do a MUC4 stain. The MUC4 is negative and on a needle it looks like a myxoma with some kind of fibrous or a little bit more cellular areas and then I just say that it's probably a cellular intramuscular myxoma. So I think MUC4",
"med_umls_ids": "[[{'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': 'myxoid', 'concept_id': 'C0205295', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}], [{'entity': 'narrator', 'concept_id': 'C1135957', 'confidence': 0.7711340188980103}, {'entity': 'cellular', 'concept_id': 'C0007634', 'confidence': 0.9999999403953552}, {'entity': 'intramuscular', 'concept_id': 'C0442117', 'confidence': 1.0}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}, {'entity': 'cellular areas', 'concept_id': 'C0007634', 'confidence': 0.7882957458496094}], [{'entity': 'MUC4', 'concept_id': 'C1417496', 'confidence': 0.9999999403953552}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'confirm', 'concept_id': 'C0521093', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'cellular intramuscular myxoma', 'concept_id': 'C1334260', 'confidence': 0.8910117149353027}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_857",
"caption_rating": "8"
},
{
"": "1007569",
"caption": "Muscle hyperplasia in the lamina propria is abnormal and should only be present in the muscularis mucosa.",
"image_path": "r7OA0Trj5hQ_image_ee9486d9-d74a-4c27-815d-5c02fa6616ac.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['muscle', 'lamina propria', 'muscularis mucosa', 'chemical gastritis', 'mucosal prolapse', 'solitary rectal ulcer syndrome', 'muscle', 'lamina propria', 'muscularis mucosa', 'chemical gastritis', 'mucosal prolapse', 'solitary rectal ulcer syndrome']",
"noisy_text": " You see in the hyperwire, muscle coming in the lamina propria. Lamina propria should be free of musculature. The muscle should be there only in the muscularis mucosa. Here in this low power, you can see the muscularis mucosa is hyperplastic. And it is sending the muscle bundle into the lamina propria. This happens in chemical gastritis in case of stomach and in cases of mucosal prolapse in colon. Remember that solitary rectal ulcer syndrome, which is totally misnomer. It is neither solitary, can be seen in other parts other than rectum. There may not be any ulcer, there is no syndrome. So the whole solitary rectal ulcer syndrome is a misnomer. But muscularization of the lamina propria is one of the criteria for mucosal prolapse that is happening in",
"corrected_text": " You see in the hyperplasia, muscle coming in the lamina propria. Lamina propria should be free of musculature. The muscle should be there only in the muscularis mucosa. Here in this low power, you can see the muscularis mucosa is hyperplastic. And it is sending the muscle bundle into the lamina propria. This happens in chemical gastritis in case of stomach and in cases of mucosal prolapse in colon. Remember that solitary rectal ulcer syndrome, which is totally misnomer. It is neither solitary, can be seen in other parts other than rectum. There may not be any ulcer, there is no syndrome. So the whole solitary rectal ulcer syndrome is a misnomer. But muscularization of the lamina propria is one of the criteria for mucosal prolapse that is happening in",
"med_umls_ids": "[[{'entity': 'Muscle hyperplasia', 'concept_id': 'C2265913', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'abnormal', 'concept_id': 'C0205161', 'confidence': 1.0}, {'entity': 'muscularis mucosa', 'concept_id': 'C0225357', 'confidence': 0.9999998807907104}], [{'entity': 'Muscle bundles', 'concept_id': 'C0504095', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'hyperplasia', 'concept_id': 'C0020507', 'confidence': 1.0}, {'entity': 'muscularis mucosa', 'concept_id': 'C0225357', 'confidence': 0.9999998807907104}], [{'entity': 'Muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'criterion', 'concept_id': 'C0243161', 'confidence': 1.0}, {'entity': 'mucosal prolapse', 'concept_id': 'C0034888', 'confidence': 0.826268196105957}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_858",
"caption_rating": "9"
},
{
"": "1007825",
"caption": "Pattern of inflammation can be observed in patients with chlamydia.",
"image_path": "sDFjOtMAYrk_image_52a027e7-1248-49df-9d15-123a08cfbffe.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "[]",
"noisy_text": " Yeah. Nope. Endoscopically and histologically, proximal biopsies are normal. Yeah. So the clinical also, if you know what the endoscopic procedure show, that's really, really helpful. You know, the patient's male. Have I had cases in females? No. Have I tried to give females STI proctitis? Yes. Have I been running every single case? Yes. Are there cases reported of patients with rectal chlamydia? Yes, but I have not come across. I'm the only one that we had turned out to be a transgender female. Another, you know, episode where I went down the tubes is I suggested the possibility of STI proctitis in this male patient because it really looked like STI proctitis. A year later, he gets another biopsy and it's full blown IBD. So early in the course of IBD, STI proctitis can really, the cases can look a lot like STI proctitis. So yeah. And this is a patient with chlamydia. I'm sorry, the slide is a little bit faded. I don't know why because it's from 2015, but this is just goes to show you how the pattern of inflammation and distortion is",
"corrected_text": " Yeah. Nope. Endoscopically and histologically, proximal biopsies are normal. Yeah. So the clinical also, if you know what the endoscopic procedure show, that's really, really helpful. You know, the patient's male. Have I had cases in females? No. Have I tried to give females STI proctitis? Yes. Have I been running every single case? Yes. Are there cases reported of patients with rectal chlamydia? Yes, but I have not come across. I'm the only one that we had turned out to be a transgender female. Another, you know, episode where I went down the tubes is I suggested the possibility of STI proctitis in this male patient because it really looked like STI proctitis. A year later, he gets another biopsy and it's full active IBD. So early in the course of IBD, STI proctitis can really, the cases can look a lot like STI proctitis. So yeah. And this is a patient with chlamydia. I'm sorry, the slide is a little bit faded. I don't know why because it's from 2015, but this is just goes to show you how the pattern of inflammation and distortion is",
"med_umls_ids": "[[{'entity': 'Proximal', 'concept_id': 'C0205107', 'confidence': 0.9999999403953552}, {'entity': 'biopsies', 'concept_id': 'C0005558', 'confidence': 1.0}, {'entity': 'endoscopically', 'concept_id': 'C0014245', 'confidence': 0.7536628842353821}, {'entity': 'histologically', 'concept_id': 'C0205462', 'confidence': 1.0}], [{'entity': 'STI', 'concept_id': 'C0036916', 'confidence': 1.0}, {'entity': 'proctitis', 'concept_id': 'C0033246', 'confidence': 0.9999999403953552}, {'entity': 'early', 'concept_id': 'C1279919', 'confidence': 1.0}, {'entity': 'IBD', 'concept_id': 'C0021390', 'confidence': 1.0}], [{'entity': 'Cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'rectal chlamydia', 'concept_id': 'C0008148', 'confidence': 0.8654578924179077}], [{'entity': 'Pattern', 'concept_id': 'C0449774', 'confidence': 1.0}, {'entity': 'inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}, {'entity': 'patients', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'chlamydia', 'concept_id': 'C0008148', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_859",
"caption_rating": "7"
},
{
"": "1004250",
"caption": "The low-grade fibromyxoid sarcoma or Evans tumor usually does not have pleomorphism, which is distinctly different from myxofibrosarcoma.",
"image_path": "QDb68_G1HR4_image_ca0e2f46-8d10-415b-995e-fc44a120a6b2.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " kind of rounded or triangle shaped but even still we really just don't see anything that looks like marked atypia or pleomorphism which is distinctly different from myxofibrosarcoma which again I have another video about that I'll put a link in the video description and up in the upper right hand corner. Myxofibrosarcomas are by definition pleomorphic sarcomas, they're aneuploid, they do not have translocations, they have random gains and losses and thus they have pleomorphism. So even in the grade 1, the low grade form of myxofibrosarcoma, you have to have pleomorphism, that's a different tumor than this low grade fibromyxoid sarcoma or Evans tumor which usually does not have pleomorphism, okay? So the myxoid areas here look a little different than the fibrous areas. So I'm",
"corrected_text": " kind of rounded or triangle shaped but even still we really just don't see anything that looks like marked atypia or pleomorphism which is distinctly different from myxofibrosarcoma which again I have another video about that I'll put a link in the video description and up in the upper right hand corner. myxofibrosarcoma are by definition pleomorphic sarcomas, they're aneuploid, they do not have translocations, they have random gains and losses and thus they have pleomorphism. So even in the grade 1, the low grade form of myxofibrosarcoma, you have to have pleomorphism, that's a different tumor than this low grade fibromyxoid sarcoma or Evans tumor which usually does not have pleomorphism, okay? So the myxoid areas here look a little different than the fibrous areas. So I'm",
"med_umls_ids": "[[{'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'Evans tumor', 'concept_id': 'C2697858', 'confidence': 0.6359843015670776}, {'entity': 'pleomorphism', 'concept_id': 'C0032219', 'confidence': 1.0}, {'entity': 'myxofibrosarcoma', 'concept_id': 'C3714524', 'confidence': 1.0}], [{'entity': 'Myxofibrosarcoma', 'concept_id': 'C3714524', 'confidence': 1.0}, {'entity': 'pleomorphic sarcoma', 'concept_id': 'C1261358', 'confidence': 0.9260651469230652}, {'entity': 'aneuploidy', 'concept_id': 'C0002938', 'confidence': 1.0}, {'entity': 'random', 'concept_id': 'C0034656', 'confidence': 1.0}, {'entity': 'gains', 'concept_id': 'C1517378', 'confidence': 0.7974324226379395}, {'entity': 'losses', 'concept_id': 'C0018840', 'confidence': 0.786555290222168}], [{'entity': 'myxoid areas', 'concept_id': 'C0205295', 'confidence': 0.8464413285255432}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'fibrous areas', 'concept_id': 'C0439709', 'confidence': 0.783623218536377}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_860",
"caption_rating": "9"
},
{
"": "1004713",
"caption": "Trichodiscoma and perifollicular fibroma are associated lesions that are likely the same as fibrofolliculoma.",
"image_path": "LlPaENuqzVQ_image_6b49a2eb-80ea-4e78-a018-03325c327ea5.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['No clefting between the lesion', 'No clefting between the lesion']",
"noisy_text": " and the follicular elements, as well as the perifollicular connective tissue. And it's kind of got this pretty characteristic, it's kind of a relatively dense fibrous stroma. It's not loose and mixoid like the stroma you see around the basal cell carcinoma. Notice that there's no clefting between this, like we see with the basal cell carcinoma. So this is fibrofolliculoma. There's two other lesions that are associated with that. They're really the same lesion. In other words, if you just get mostly fibrous with a little teensy, tiny strand of epithelium left, that's either going to be a trichodyscoma or a perifollicular fibroma. And those are really, they're probably really all the same lesion, just they kind of look a little bit different. So that's kind of important to know that from the",
"corrected_text": " and the follicular elements, as well as the perifollicular connective tissue. And it's kind of got this pretty characteristic, it's kind of a relatively dense fibrous stroma. It's not loose and mixoid like the stroma you see around the basal cell carcinoma. Notice that there's no clefting between this, like we see with the basal cell carcinoma. So this is fibrofolliculoma. There's two other lesions that are associated with that. They're really the same lesion. In other words, if you just get mostly fibrous with a little teensy, tiny strand of epithelium left, that's either going to be a trichodiscoma or a perifollicular fibroma. And those are really, they're probably really all the same lesion, just they kind of look a little bit different. So that's kind of important to know that from the",
"med_umls_ids": "[[{'entity': 'Describes', 'concept_id': 'C1552738', 'confidence': 0.7625278830528259}, {'entity': 'physical characteristics', 'concept_id': 'C1521970', 'confidence': 0.8302092552185059}, {'entity': 'fibrofolliculoma', 'concept_id': 'C0346011', 'confidence': 1.0}, {'entity': 'fibrous', 'concept_id': 'C0439709', 'confidence': 1.0}, {'entity': 'clefting', 'concept_id': 'C4021813', 'confidence': 0.8906428217887878}, {'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}], [{'entity': 'Trichodiscoma', 'concept_id': 'C0346011', 'confidence': 1.0}, {'entity': 'perifollicular fibroma', 'concept_id': 'C1704236', 'confidence': 1.0}, {'entity': 'lesions', 'concept_id': 'C0221198', 'confidence': 1.0}, {'entity': 'fibrofolliculoma', 'concept_id': 'C0346011', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_861",
"caption_rating": "8"
},
{
"": "1005611",
"caption": "The glands in the area being examined show patchy positivity for basal cell markers, but some are completely negative, causing concern for cancer. However, this is actually a benign process called partial atrophy.",
"image_path": "iklRyY1nBIE_image_19dd8884-490b-48e9-b982-d85cdc717d79.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['Glands with patchy basal positivity', 'Partially atrophic glands with varying cytoplasm and cystic dilation']",
"noisy_text": " The problem is when we come to this area we were looking at earlier, you can see that some of the glands show patchy positivity for the basal cell markers, but some of them are completely negative. And to complicate things even more, some of these glands are positive for racemase or amarkar, so-called amarkar, and that causes a lot of concern. So that's why they were struggling with this case, because if you see positive racemase expression, which is typically positive in cancer, and you see negative basal cell expression, the impression people have is that you're dealing with cancer. But that's not always the case, and that's why I'm sharing this case with all of you, because this is actually a process called partial atrophy. The glands I showed you on H&E are partially atrophic. You can still see some of it here. Some of them are cystically dilated here. In some areas you can see more cytoplasm. In other areas it looks more atrophic. So even on this paint cocktail, you can appreciate the partially atrophic features. So this is a benign process. You should not call this cancer, and you should not be too generous with your atypical diagnosis either, or some people call it atypical small atrial proliferation. You should not render that diagnosis too frequently, otherwise your clinical colleagues won't trust your histologic judgment. So one has to be very careful with that. One should use that term very sparingly. So this is partial atrophy, and it's not unusual to have this kind of picture. If all the glands show patchy basal positivity, then that makes it an easy case. But some cases are tricky like this one, where some of the glands are completely negative for basal cell markers, while others are patchy positive for basal cell markers. But once you recognize on the H and E that both, you know, all these glands have similar cytologic features, both in the nucleus and the cytoplasm, that should make your life very easy. So this was a very good case of partial atrophy. I have some other cases I'll share with you very quickly. Similar scenario,",
"corrected_text": " The problem is when we come to this area we were looking at earlier, you can see that some of the glands show patchy positivity for the basal cell markers, but some of them are completely negative. And to complicate things even more, some of these glands are positive for racemase or AMACR, so-called AMACR, and that causes a lot of concern. So that's why they were struggling with this case, because if you see positive racemase expression, which is typically positive in cancer, and you see negative basal cell expression, the impression people have is that you're dealing with cancer. But that's not always the case, and that's why I'm sharing this case with all of you, because this is actually a process called partial atrophy. The glands I showed you on H&E are partially atrophic. You can still see some of it here. Some of them are cystically dilated here. In some areas you can see more cytoplasm. In other areas it looks more atrophic. So even on this paint cocktail, you can appreciate the partially atrophic features. So this is a benign process. You should not call this cancer, and you should not be too generous with your atypical diagnosis either, or some people call it atypical small atrial proliferation. You should not render that diagnosis too frequently, otherwise your clinical colleagues won't trust your histologic judgment. So one has to be very careful with that. One should use that term very sparingly. So this is partial atrophy, and it's not unusual to have this kind of picture. If all the glands show patchy basal positivity, then that makes it an easy case. But some cases are tricky like this one, where some of the glands are completely negative for basal cell markers, while others are patchy positive for basal cell markers. But once you recognize on the H and E that both, you know, all these glands have similar cytologic features, both in the nucleus and the cytoplasm, that should make your life very easy. So this was a very good case of partial atrophy. I have some other cases I'share with you very quickly. Similar scenario,",
"med_umls_ids": "[[{'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'area', 'concept_id': 'C0017446', 'confidence': 1.0}, {'entity': 'patchy', 'concept_id': 'C0205413', 'confidence': 1.0}, {'entity': 'positivity', 'concept_id': 'C4280732', 'confidence': 0.8599872589111328}, {'entity': 'basal cell', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'markers', 'concept_id': 'C0181734', 'confidence': 0.890313982963562}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'cancer', 'concept_id': 'C0006826', 'confidence': 0.9999998807907104}, {'entity': 'benign process', 'concept_id': 'C0205183', 'confidence': 0.7677057981491089}, {'entity': 'partial', 'concept_id': 'C0728938', 'confidence': 1.0}, {'entity': 'atrophy', 'concept_id': 'C0333641', 'confidence': 1.0}], [{'entity': 'Partial atrophy', 'concept_id': 'C1265892', 'confidence': 1.0}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'atrophic glands', 'concept_id': 'C5194745', 'confidence': 0.8184286952018738}, {'entity': 'cystically', 'concept_id': 'C0205207', 'confidence': 0.6787945628166199}, {'entity': 'dilated', 'concept_id': 'C0700124', 'confidence': 0.9999999403953552}, {'entity': 'cytoplasm', 'concept_id': 'C0010834', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_862",
"caption_rating": "8"
},
{
"": "1005312",
"caption": "Discussion of panic cell metaplasia and pyloric gland metaplasia in the context of inflammatory processes.",
"image_path": "sDFjOtMAYrk_image_23797393-6952-4b1e-bd77-65cd0998fcbe.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['panic cell metaplasia', 'pyloric gland metaplasia', 'inflammatory bowel disease']",
"noisy_text": " chronicity? Yes, panic cell metaplasia. Is it specific? No. Can you see it in like drugs and other like, collagenous colitis, other types of inflammatory processes? Yes. So, the other finding would be pyloric gland metaplasia, which I find a little bit more difficult to spot if you're not really looking for it because the glands kind of blend in to the, you know, the background colonic mucosa. But once you learn to look for it, you'll find and we'll see a little bit of it further down the road. So, this is a case of inflammatory bowel disease. And this is what I like to compare everything to in order to avoid labeling patients with IBD who don't have IBD and",
"corrected_text": " chronicity? Yes, panic cell metaplasia. Is it specific? No. Can you see it in like drugs and other like, collagenous colitis, other types of inflammatory processes? Yes. So, the other finding would be pyloric gland metaplasia, which I find a little bit more difficult to spot if you're not really looking for it because the glands kind of blend in to the, you know, the background colonic mucosa. But once you learn to look for it, you'll find and we'll see a little bit of it further down the road. So, this is a case of inflammatory bowel disease. And this is what I like to compare everything to in order to avoid labeling patients with IBD who don't have IBD and",
"med_umls_ids": "[[{'entity': 'panic cell metaplasia', 'concept_id': 'C0025568', 'confidence': 0.7588340044021606}, {'entity': 'pyloric gland metaplasia', 'concept_id': 'C4288813', 'confidence': 1.0}, {'entity': 'context', 'concept_id': 'C0449255', 'confidence': 1.0}, {'entity': 'inflammatory processes', 'concept_id': 'C0333348', 'confidence': 0.7974503636360168}], [{'entity': 'Pyloric gland', 'concept_id': 'C0227239', 'confidence': 1.0}, {'entity': 'metaplasia', 'concept_id': 'C0025568', 'confidence': 1.0}, {'entity': 'identified', 'concept_id': 'C0205396', 'confidence': 1.0}, {'entity': 'practice', 'concept_id': 'C0237607', 'confidence': 1.0}], [{'entity': 'Case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'inflammatory bowel disease', 'concept_id': 'C0021390', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_863",
"caption_rating": "8"
},
{
"": "1008421",
"caption": "The diagnosis is chronic radiation dermatitis, likely caused by radiation.",
"image_path": "udoW6VSqsm4_image_1409c112-ae10-4526-82a6-7a5b2ea13a1a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['Homogenization necrosis of collagen bundles', 'Stellate fibroblasts', 'Telangiectasis', 'Bizarre and irregular blood vessels', 'Fibroblasts with irregular and bizarre morphology']",
"noisy_text": " There's homogenization of collagen bundles. There's all of this. There's very few scattered little stellate fibroblasts. Yeah, good. So, what's the diagnosis? It's chronic radiation dermatitis. Yeah, chronic radiation dermatitis. And this is probably from the radiation. Now, it looks like solar elastosis. There may be some solar elastosis also. But if you radiate somebody's skin, they get elastotic material also. So, UV is not the only thing that causes that. You can get solar elastosis. You can also get radiation-induced elastosis. So, this is chronic radiation dermatitis in this case. You can get telangiectasis. Sometimes the blood vessels can be kind of bizarre and irregular also, fibroblasts can be stellated and irregular and bizarre. So, I don't remember what this patient had, why they were radiated, but this was chronic radiodermatitis. And they often",
"corrected_text": " There's homogenization of collagen bundles. There's all of this. There's very few scattered little stellate fibroblasts. Yeah, good. So, what's the diagnosis? It's chronic radiation dermatitis. Yeah, chronic radiation dermatitis. And this is probably from the radiation. Now, it looks like solar elastosis. There may be some solar elastosis also. But if you radiate somebody's skin, they get elastotic material also. So, UV is not the only thing that causes that. You can get solar elastosis. You can also get radiation-induced elastosis. So, this is chronic radiation dermatitis in this case. You can get telangiectasis. Sometimes the blood vessels can be kind of bizarre and irregular also, fibroblasts can be stellate and irregular and bizarre. So, I don't remember what this patient had, why they were radiated, but this was chronic radiodermatitis. And they often",
"med_umls_ids": "[[{'entity': 'Homogenization necrosis', 'concept_id': 'C0027540', 'confidence': 0.5868868231773376}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'bundles', 'concept_id': 'C3658308', 'confidence': 0.8706014752388}, {'entity': 'scattered', 'concept_id': 'C0439742', 'confidence': 1.0}, {'entity': 'stellate', 'concept_id': 'C0205141', 'confidence': 0.9999999403953552}, {'entity': 'fibroblasts', 'concept_id': 'C0016030', 'confidence': 1.0}], [{'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'chronic radiation dermatitis', 'concept_id': 'C0263607', 'confidence': 1.0}, {'entity': 'radiation', 'concept_id': 'C0034519', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_864",
"caption_rating": "7"
},
{
"": "1009421",
"caption": "Presence of cribriform glands surrounded by basal cells.",
"image_path": "iklRyY1nBIE_image_68139a77-461a-4fd8-9b28-921455cee06c.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['Adenocarcinoma of the prostate', 'Polyform and single cells in some glands', 'Cribriform glands surrounded by basal cells']",
"noisy_text": " So you have both an infiltrative process, which looks like conventional prostate cancer. Some of the glands are polyform. Some of them are actually single cells. So this is a high-grade tumor, very busy, very busy slide. And then you have cribriform glands that look like they are surrounded by basal cells. So the question is, what do you do with this kind of morphology? What do you call this? But we'll get to that in a second. Let me show you what the cocktail looks like. Again, this is the pin three, or some call it pin four. You have",
"corrected_text": " So you have both an infiltrative process, which looks like conventional prostate cancer. Some of the glands are polyform. Some of them are actually single cells. So this is a high-grade tumor, very busy, very busy slide. And then you have cribriform glands that look like they are surrounded by basal cells. So the question is, what do you do with this kind of morphology? What do you call this? But we'll get to that in a second. Let me show you what the cocktail looks like. Again, this is the pin three, or some call it pin four. You have",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'infiltrative process', 'concept_id': 'C4527217', 'confidence': 0.8470810055732727}, {'entity': 'adenocarcinoma', 'concept_id': 'C0001418', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'polyform', 'concept_id': 'C0071571', 'confidence': 1.0}, {'entity': 'single cells', 'concept_id': 'C0037179', 'confidence': 0.7283049821853638}, {'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'cribriform glands', 'concept_id': 'C1285092', 'confidence': 0.6162902116775513}, {'entity': 'surrounded', 'concept_id': 'C1282914', 'confidence': 1.0}, {'entity': 'basal cells', 'concept_id': 'C0596155', 'confidence': 1.0}], [{'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_865",
"caption_rating": "8"
},
{
"": "1004965",
"caption": "Identification of different types of protein fibers in connective tissue.",
"image_path": "ib991vTA67A_image_09d9bb64-7a85-4ad4-8a54-9fd2c6bc4c7f.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Head and Neck']",
"roi_text": "['fat, fatter, thick, pink protein fibers', 'Connective Tissue', 'skinny collagen fibers', 'fat, fatter, thick, pink protein fibers', 'Connective Tissue', 'skinny collagen fibers', 'fat, fatter, thick, pink protein fibers']",
"noisy_text": " and three places where you could find this type of Connective Tissue. So here's this Connective Tissue again, just write it down, and the next question is what type of protein fibers are these skinny ones, these skinny hair-like protein fibers? Find those protein fibers first, the skinny hair-like protein fibers, what are those called? And next, what are these fat, fatter, thick, pink protein fibers called? What are these protein fibers called? Here's a close-up of a Connective Tissue you've seen, so this is going to be number twenty-four, what type",
"corrected_text": " and three places where you could find this type of Connective Tissue. So here's this Connective Tissue again, just write it down, and the next question is what type of protein fibers are these skinny ones, these skinny hair-like protein fibers? Find those protein fibers first, the skinny hair-like protein fibers, what are those called? And next, what are these fat, fatter, thick, pink protein fibers called? What are these protein fibers called? Here's a close-up of a Connective Tissue you've seen, so this is going to be number twenty-four, what type",
"med_umls_ids": "[[{'entity': 'Identification', 'concept_id': 'C0020792', 'confidence': 1.0}, {'entity': 'protein fibers', 'concept_id': 'C0000696', 'confidence': 0.7645217180252075}, {'entity': 'connective tissue', 'concept_id': 'C0009780', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1152.0",
"id": "test_866",
"caption_rating": "8"
},
{
"": "1004669",
"caption": "Lamina propria edema and muscularis mucosa coming into the lamina propria are criteria for chemical gastritis.",
"image_path": "r7OA0Trj5hQ_image_c6eb73a1-9f9f-4e7a-911d-5342b8bef44b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['lamina propria edema', 'muscularis mucosa', 'neutrophils', 'eosinophils', 'stomach', 'esophagus', 'enteritis', 'colitis', 'lamina propria edema', 'muscularis mucosa', 'neutrophils', 'eosinophils', 'stomach', 'esophagus', 'enteritis', 'colitis']",
"noisy_text": " Lamina propria edema and muscularis mucosa coming into the lamina propria. These are the three criterias. When you see it in the anterobiopsy, think of chemical gastritis that can be seen in biliary reflux or NSAID use. Lot of inflammation results. Remember I told you if you see more than five neutrophils, more than five eosinophils sitting in the lamina propria or more than 15 eosinophils per high power field, that is a eosinophilic gastritis, if it is from the stomach. If it is esophagus, it is eosinophilic esophagitis, eosinophilic entritis, eosinophilic colitis. So eosinophilic",
"corrected_text": " Lamina propria edema and muscularis mucosa coming into the lamina propria. These are the three criterias. When you see it in the antral biopsy, think of chemical gastritis that can be seen in biliary reflux or NSAID use. Lot of inflammation results. Remember I told you if you see more than five neutrophils, more than five eosinophils sitting in the lamina propria or more than 15 or more eosinophils per high power field, that is a eosinophilic gastritis, if it is from the stomach. If it is esophagus, it is eosinophilic esophagitis, eosinophilic enteritis, eosinophilic colitis. So eosinophilic",
"med_umls_ids": "[[{'entity': 'Lamina propria edema', 'concept_id': 'C1179187', 'confidence': 0.7593827247619629}, {'entity': 'muscularis mucosa', 'concept_id': 'C0225357', 'confidence': 0.9999998807907104}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'criteria', 'concept_id': 'C0243161', 'confidence': 0.9999998807907104}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}], [{'entity': 'Inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}], [{'entity': 'Eosinophilic gastritis', 'concept_id': 'C0267154', 'confidence': 1.0}, {'entity': 'diagnosed', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}], [{'entity': 'Eosinophilic esophagitis', 'concept_id': 'C0341106', 'confidence': 0.9999999403953552}, {'entity': 'eosinophilic enteritis', 'concept_id': 'C1262481', 'confidence': 1.0}, {'entity': 'eosinophilic colitis', 'concept_id': 'C0267448', 'confidence': 1.0}, {'entity': 'diagnoses', 'concept_id': 'C0011900', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_867",
"caption_rating": "8"
},
{
"": "1009391",
"caption": "Poorly differentiated cancer cells are visible in the submucosa.",
"image_path": "r7OA0Trj5hQ_image_8e572332-7aec-4c08-9283-1f9ef1613002.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['submucosa', 'poorly differentiated cancer cells', 'invasive carcinoma', 'blood vessels']",
"noisy_text": " And why I am showing it, sometimes you may think of malignancy. Here, you may not think of it. And another point, these are all the cells we are looking in congenital mecagola. So if you don't see them in the submicosa in frozen section, again, this will qualify for congenital mecagola. Here, another tricky thing. This is submicosa, and you can see the poorly differentiated cancer cells. And these are invasive carcinoma. Now, you see this number of blood vessels there. That's why we need the cancer cell to come into the submicosa to call it as cancer cell, because the incidence of metastasis is very",
"corrected_text": " And why I am showing it, sometimes you may think of malignancy. Here, you may not think of it. And another point, these are all the cells we are looking in congenital megacolon. So if you don't see them in the submucosa in frozen section, again, this will qualify for congenital megacolon. Here, another tricky thing. This is submucosa, and you can see the poorly differentiated cancer cells. And these are invasive carcinoma. Now, you see this number of blood vessels there. That's why we need the cancer cell to come into the submucosa to call it as cancer cell, because the incidence of metastasis is very",
"med_umls_ids": "[[{'entity': 'narrator', 'concept_id': 'C1135957', 'confidence': 0.7711340188980103}, {'entity': 'malignancy', 'concept_id': 'C0006826', 'confidence': 1.0}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'congenital megacolon', 'concept_id': 'C0019569', 'confidence': 1.0}], [{'entity': 'Poorly differentiated', 'concept_id': 'C0205617', 'confidence': 1.0}, {'entity': 'cancer cells', 'concept_id': 'C0334227', 'confidence': 0.9999998807907104}, {'entity': 'visible', 'concept_id': 'C0205379', 'confidence': 0.9999998807907104}, {'entity': 'submucosa', 'concept_id': 'C0225344', 'confidence': 1.0}], [{'entity': 'cancer cells', 'concept_id': 'C0334227', 'confidence': 0.9999998807907104}, {'entity': 'invade', 'concept_id': 'C1517574', 'confidence': 0.857607364654541}, {'entity': 'submucosa', 'concept_id': 'C0225344', 'confidence': 1.0}, {'entity': 'cancerous', 'concept_id': 'C1514391', 'confidence': 0.763753354549408}, {'entity': 'incidence', 'concept_id': 'C0021149', 'confidence': 1.0}, {'entity': 'metastasis', 'concept_id': 'C0027627', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_868",
"caption_rating": "8"
},
{
"": "1009252",
"caption": "Description of a soft tissue neoplasm with diffuse involvement and a honeycomb morphology, characteristic of desmoplastic fibroblastoma.",
"image_path": "LlPaENuqzVQ_image_0ff2cc75-1270-40de-8821-f503b9118e5e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['Diffuse involvement', 'Subcutaneous fat', 'Honeycomb morphology']",
"noisy_text": " And so this is another soft tissue neoplasm. So low magnification, you can see it's very diffuse, top to bottom, side to side, everything's involved here. So those things would be very poorly, poorly circumscribed. And when you get out of the subcutaneous fat, this is a clue to this diagnosis. You can make this diagnosis at low power when you see this pattern. This is a honeycomb morphology. Rarely anything does this except dramatic fibrosarcoma tuberans. Okay, when you see this pattern, you can impress your friends and colleagues. You can say, this is DFSB. You don't need the storiform pattern.",
"corrected_text": " And so this is another soft tissue neoplasm. So low magnification, you can see it's very diffuse, top to bottom, side to side, everything's involved here. So those things would be very poorly, poorly circumscribed. And when you get out of the subcutaneous fat, this is a clue to this diagnosis. You can make this diagnosis at low power when you see this pattern. This is a honeycomb morphology. Rarely anything does this except dramatic fibrosarcoma tuberans. Okay, when you see this pattern, you can impress your friends and colleagues. You can say, this is DFSB. You don't need the storiform pattern.",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'soft tissue neoplasm', 'concept_id': 'C0037579', 'confidence': 1.0}, {'entity': 'diffuse', 'concept_id': 'C0205219', 'confidence': 1.0}, {'entity': 'involvement', 'concept_id': 'C1314939', 'confidence': 1.0}, {'entity': 'honeycomb', 'concept_id': 'C0332468', 'confidence': 1.0}, {'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}, {'entity': 'desmoplastic fibroblastoma', 'concept_id': 'C0206645', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_869",
"caption_rating": "10"
},
{
"": "1006907",
"caption": "Histopathological description of pigmented Bowen\u2019s disease or pigmented squamous cell carcinoma with abnormal maturation and increased melanin pigment in the basal layer and epidermis.",
"image_path": "8S4LeiO6Bbk_image_5798b1fa-a61e-4f8b-a597-a29666a0e39f.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['abnormal hyperchromatic parakeratotic cells', 'increased amount of melanin pigment', 'dendritic melanocytes', 'pigmented Bowen\u2019s disease', 'pigmented squamous cell carcinoma', 'psoriasis form dermatitis', 'inflamed pigmented seborrheic keratosis']",
"noisy_text": " pleomorphic and hyperchromatic. There is abnormal maturation with even abnormal hyperchromatic perikaratotic cells within the stratum corneum. There's an increased amount of melanin pigment pressed within the basal layer and we can see that we've got an increased amount of melanin pigment and even a few dendritic melanocytes within the epidermis and so what we've got here is an example of pigmented Bowen's disease or pigmented squamous cell carcinoma. One could see similar changes in lesions too of boenoid papillosis and if this was one of many or a few papules on the genitalia one would have to keep boenoid papillosis and the differential as well here but this is one of these lesions that kind of is a fooler because it has a benign silhouette, resembles a psoriasis form dermatitis or even an inflamed pigmented seborrheic keratosis but it always behooves you to go",
"corrected_text": " pleomorphic and hyperchromatic. There is abnormal maturation with even abnormal hyperchromatic parakeratotic cells within the stratum corneum. There's an increased amount of melanin pigment pressed within the basal layer and we can see that we've got an increased amount of melanin pigment and even a few dendritic melanocytes within the epidermis and so what we've got here is an example of pigmented Bowen 's disease's disease or pigmented squamous cell carcinoma. One could see similar changes in lesions too of Bowenoid papulosis and if this was one of many or a few papules on the genitalia one would have to keep Bowenoid papulosis and the differential as well here but this is one of these lesions that kind of is a misleading because it has a benign silhouette, resembles a psoriasis form dermatitis or even an inflamed pigmented seborrheic keratosis but it always behooves you to go",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'Bowen\u2019s disease', 'concept_id': 'C0006079', 'confidence': 0.9730859994888306}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'squamous cell carcinoma', 'concept_id': 'C0007137', 'confidence': 1.0}, {'entity': 'abnormal', 'concept_id': 'C0205161', 'confidence': 1.0}, {'entity': 'maturation', 'concept_id': 'C0678723', 'confidence': 1.0}, {'entity': 'increased', 'concept_id': 'C0205217', 'confidence': 1.0}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}, {'entity': 'pigment', 'concept_id': 'C0031911', 'confidence': 1.0}, {'entity': 'basal layer', 'concept_id': 'C0221925', 'confidence': 1.0}, {'entity': 'epidermis', 'concept_id': 'C0014520', 'confidence': 1.0}], [{'entity': 'changes', 'concept_id': 'C0392747', 'confidence': 1.0}, {'entity': 'lesions', 'concept_id': 'C0221198', 'confidence': 1.0}, {'entity': 'Bowenoid papulosis', 'concept_id': 'C0334106', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_870",
"caption_rating": "9"
},
{
"": "1004926",
"caption": "Discussion of the unusual behavior of a tumor that looks benign but has a different behavior than other sarcomas, with a median time to metastasis of 15 years and cases reported up to 30 or 40 years after the original diagnosis.",
"image_path": "QDb68_G1HR4_image_64ba65d7-1468-40c6-90e1-034c788b42fb.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['metastases to lung or pleura']",
"noisy_text": " If you follow patients much longer, the picture changes quite a bit and a significant subset, somewhere around 40 or even maybe even higher percent will eventually get metastases if you follow them over decades and that's what's so unusual about this tumor, not only does it look benign, it is a very, very different behavior than other sarcomas. Most high-grade sarcomas metastasize oftentimes within 5 years of diagnosis if they're going to metastasize. Now that's not always true, but oftentimes that's the case. This tumor is so different, I think the median time to metastasis in a large retrospective study by Harry Evans, I think that was published in American Journal of Surgical Pathology 2011, I'll put a link in the video description. If you follow them for many, many years, the average time, I think it was the median time actually to recurrence or to metastasis was 15 years, that's so strange, right, to have a tumor that waits 15 years to eventually spread or recur and that's not all. There are cases reported that are actually 30 or even 40 years out from the original diagnosis when a metastasis finally shows up. So unfortunately, that's a frustrating thing I think for both the treating physicians and the patients to know that basically you're never totally in the clear these things can recur or metastasize very, very long after diagnosis. When they metastasize, they often go to the lung or the pleura and there probably is some benefit at least",
"corrected_text": " If you follow patients much longer, the picture changes quite a bit and a significant subset, somewhere around 40 or even maybe even higher percent will eventually get metastases if you follow them over decades and that's what's so unusual about this tumor, not only does it look benign, it is a very, very different behavior than other sarcomas. Most high-grade sarcomas metastasize oftentimes within 5 years of diagnosis if they're going to metastasize. Now that's not always true, but oftentimes that's the case. This tumor is so different, I think the median time to metastasis in a large retrospective study by Harry Evans, I think that was published in American Journal of Surgical Pathology 2011, I'll put a link in the video description. If you follow them for many, many years, the average time, I think it was the median time actually to recurrence or to metastasis was 15 years, that's so strange, right, to have a tumor that waits 15 years to eventually spread or recur and that's not all. There are cases reported that are actually 30 or even 40 years out from the original diagnosis when a metastasis finally shows up. So unfortunately, that's a frustrating thing I think for both the treating physicians and the patients to know that basically you're never totally in the clear these things can recur or metastasize very, very long after diagnosis. When they metastasize, they often go to the lung or the pleura and there probably is some benefit at least",
"med_umls_ids": "[[{'entity': 'unusual', 'concept_id': 'C2700116', 'confidence': 1.0}, {'entity': 'behavior', 'concept_id': 'C0004927', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'benign', 'concept_id': 'C0205183', 'confidence': 1.0}, {'entity': 'behavior', 'concept_id': 'C0004927', 'confidence': 1.0}, {'entity': 'sarcomas', 'concept_id': 'C1261473', 'confidence': 1.0}, {'entity': 'median', 'concept_id': 'C0549183', 'confidence': 1.0}, {'entity': 'metastasis', 'concept_id': 'C0027627', 'confidence': 1.0}, {'entity': 'years', 'concept_id': 'C0439234', 'confidence': 1.0}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'years', 'concept_id': 'C0439234', 'confidence': 1.0}, {'entity': 'original', 'concept_id': 'C0205313', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'Metastases', 'concept_id': 'C0027627', 'confidence': 1.0}, {'entity': 'lung', 'concept_id': 'C0024109', 'confidence': 1.0}, {'entity': 'pleura', 'concept_id': 'C0032225', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_871",
"caption_rating": "7"
},
{
"": "1005503",
"caption": "Sclerotic stroma with a second distinct morphologic population of melanocytes.",
"image_path": "8S4LeiO6Bbk_image_2a656e84-f2e1-48c2-9cf0-1df8b85c49a1.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['cytoplasm', 'dermis']",
"noisy_text": " appearance, a round oval nuclei and a moderate amount of cytoplasm. And then we have nest cords and strands of otherwise banal appearing or banal appearing melanocytes present within the underlying dermis. There is evidence of maturation with depth in these sections, and no mitotic pairs. In the central portion of the specimen, you can see that the dermis is a little more sclerotic. And we've got the presence of separately heavily pigmented melanovagias. And then if we look at our top piece of tissue, again, we have the more banal appearing melanocytes out of the periphery. And centrally, we've got embedded within a sclerotic stroma a second distinct morphologic population of melanocytes. Some of these are dendritic, others have spindled or fusiform-shaped",
"corrected_text": " appearance, a round oval nuclei and a moderate amount of cytoplasm. And then we have nest cords and strands of otherwise banal appearing or banal appearing melanocytes present within the underlying dermis. There is evidence of maturation with depth in these sections, and no mitotic pairs. In the central portion of the specimen, you can see that the dermis is a little more sclerotic. And we've got the presence of separately heavily pigmented melanovagias. And then if we look at our top piece of tissue, again, we have the more banal appearing melanocytes out of the periphery. And centrally, we've got embedded within a sclerotic stroma a second distinct morphologic population of melanocytes. Some of these are dendritic, others have spindle-shaped or fusiform-shaped",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'specimen', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'banal', 'concept_id': 'C0004722', 'confidence': 0.7279530763626099}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}], [{'entity': 'Evidence', 'concept_id': 'C3887511', 'confidence': 1.0}, {'entity': 'maturation', 'concept_id': 'C0678723', 'confidence': 1.0}, {'entity': 'depth', 'concept_id': 'C0205125', 'confidence': 1.0}, {'entity': 'mitotic', 'concept_id': 'C1513354', 'confidence': 1.0}, {'entity': 'pairs', 'concept_id': 'C0600436', 'confidence': 0.8094210028648376}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'heavily', 'concept_id': 'C0337678', 'confidence': 0.6902515292167664}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'melanophages', 'concept_id': 'C3280463', 'confidence': 0.9375340938568115}], [{'entity': 'Sclerotic', 'concept_id': 'C0036429', 'confidence': 0.9999999403953552}, {'entity': 'stroma', 'concept_id': 'C0927195', 'confidence': 1.0}, {'entity': 'morphologic population', 'concept_id': 'C0543482', 'confidence': 0.699425995349884}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_872",
"caption_rating": "8"
},
{
"": "1006403",
"caption": "Intestinal metaplasia is present.",
"image_path": "r7OA0Trj5hQ_image_dea08b06-85dd-4419-b590-b677fadd042a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['muscle fibers', 'intestinal metaplasia', 'lamina propria']",
"noisy_text": " where, again, you can see the muscle fibers running into the lamina propria. If you are in doubt, you can use the trichrome strain, where you can identify the muscle running up there. And you can see nice intestinal metaplasia there. Again, the number of glands are less in here. So this is chronic atrophic gastritis with intestinal metaplasia with muscularization of the lamina propria. More than one pathology involved in this biopsy. Plastic changes seen above are known as TIS. Once they cross the muscular ischemicosa, then only they are eligible for T1. So muscular ischemicosa acts like",
"corrected_text": " where, again, you can see the muscle fibers running into the lamina propria. If you are in doubt, you can use the trichrome strain, where you can identify the muscle running up there. And you can see nice intestinal metaplasia there. Again, the number of glands are less in here. So this is chronic atrophic gastritis with intestinal metaplasia with muscularization of the lamina propria. More than one pathology involved in this biopsy. Plastic changes seen above are known as TIS. Once they cross the muscularis propria, then only they are eligible for T1. So muscularis propria acts like",
"med_umls_ids": "[[{'entity': 'Muscle fibers', 'concept_id': 'C0242697', 'confidence': 1.0}, {'entity': 'running', 'concept_id': 'C0035953', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}], [{'entity': 'Intestinal metaplasia', 'concept_id': 'C0334037', 'confidence': 1.0}], [{'entity': 'Chronic atrophic gastritis', 'concept_id': 'C0017154', 'confidence': 1.0}, {'entity': 'intestinal metaplasia', 'concept_id': 'C0334037', 'confidence': 1.0}, {'entity': 'muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'Plastic changes', 'concept_id': 'C0392747', 'confidence': 0.7598782777786255}, {'entity': 'TIS', 'concept_id': 'C0475413', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_873",
"caption_rating": "8"
},
{
"": "1009024",
"caption": "The patient had a teratoma component that was not eliminated by therapy, which extended to the prostate and bladder.",
"image_path": "iklRyY1nBIE_image_7acbb91d-274f-4065-8993-6f88a1685816.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['teratoma component', 'prostate', 'bladder', 'positive digital rectal examination', 'elevated PSA level']",
"noisy_text": " tumor, got therapy, and unfortunately, had the teratoma. And this happens a lot. The therapy took care of the other embryonic, carcinoma, yolk cell tumor components, semi-normal components, et cetera, but the teratoma component stayed behind. So this is the margin that is always negative. As you can see, there is tumor present. So the teratoma extended to this area also. So this was a diffuse involvement of the prostate. There was also some bladder involvement by this tumor. So this was bad news for this gentleman. So the last case I'm going to share before we go to the Q&A is case number 10. Case number 10 is a 58-year-old gentleman with a positive digital rectal examination and elevated PSA level. So right off the bat, you can appreciate that this is an",
"corrected_text": " tumor, got therapy, and unfortunately, had the teratoma. And this happens a lot. The therapy took care of the other embryonic, carcinoma, yolk cell tumor components, normal components, et cetera, but the teratoma component stayed behind. So this is the margin that is always negative. As you can see, there is tumor present. So the teratoma extended to this area also. So this was a diffuse involvement of the prostate. There was also some bladder involvement by this tumor. So this was bad news for this gentleman. So the last case I'm going to share before we go to the Q&A is case number 10. Case number 10 is a 58-year-old gentleman with a positive digital rectal examination and elevated PSA level. So right off the bat, you can appreciate that this is an",
"med_umls_ids": "[[{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'teratoma', 'concept_id': 'C0039538', 'confidence': 1.0}, {'entity': 'component', 'concept_id': 'C0449432', 'confidence': 1.0}, {'entity': 'therapy', 'concept_id': 'C0039798', 'confidence': 0.9999999403953552}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'bladder', 'concept_id': 'C0005682', 'confidence': 1.0}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'digital rectal examination', 'concept_id': 'C0199900', 'confidence': 1.0}, {'entity': 'elevated', 'concept_id': 'C0205250', 'confidence': 0.9999999403953552}, {'entity': 'PSA', 'concept_id': 'C0138741', 'confidence': 1.0}, {'entity': 'level', 'concept_id': 'C0441889', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_874",
"caption_rating": "8"
},
{
"": "1008749",
"caption": "Xanthoma is a condition commonly seen in young males with signs and symptoms of inflammatory bowel disease.",
"image_path": "r7OA0Trj5hQ_image_8c27381b-ee6a-42e7-844a-c61938edde63.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['young males', 'inflammatory bowel disease', 'lamina propria', 'distinct cell border', 'foamy cytoplasm', 'centrally placed nucleus', 'gastric xanthoma', 'young males', 'inflammatory bowel disease', 'lamina propria', 'distinct cell border', 'foamy cytoplasm', 'centrally placed nucleus', 'gastric xanthoma']",
"noisy_text": " It is commonly seen in young males, and they present with the signs and symptoms of inflammatory bowel disease. Interesting condition. Here, the lamina propria is full of cells with a distinct cell border, abundant foamy cytoplasm, most of the time centrally placed nucleus. Sometimes it is pushed to the periphery. The central nuclear placement is very important for a diagnosis of xanthoma. For a signet cells, it will be predominantly peripherally pushed nucleus. And when you have doubt, you do a CD68, which will be strongly positive. And so this is a gastric xanthoma. Here, it",
"corrected_text": " It is commonly seen in young males, and they present with the signs and symptoms of inflammatory bowel disease. Interesting condition. Here, the lamina propria is full of cells with a distinct cell border, abundant foamy cytoplasm, most of the time centrally placed nucleus. Sometimes it is pushed to the periphery. The central nuclear placement is very important for a diagnosis of xanthoma. For a signet ring cells, it will be predominantly peripherally pushed nucleus. And when you have doubt, you do a CD68, which will be strongly positive. And so this is a gastric xanthoma. Here, it",
"med_umls_ids": "[[{'entity': 'Xanthoma', 'concept_id': 'C0302314', 'confidence': 1.0}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'young', 'concept_id': 'C0332239', 'confidence': 1.0}, {'entity': 'males', 'concept_id': 'C0086582', 'confidence': 1.0}, {'entity': 'signs', 'concept_id': 'C0220912', 'confidence': 0.9999999403953552}, {'entity': 'symptoms', 'concept_id': 'C0683368', 'confidence': 1.0}, {'entity': 'inflammatory bowel disease', 'concept_id': 'C0021390', 'confidence': 1.0}], [{'entity': 'Lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'cell border', 'concept_id': 'C0205284', 'confidence': 0.773768424987793}, {'entity': 'foamy cytoplasm', 'concept_id': 'C0010834', 'confidence': 0.7207725048065186}, {'entity': 'centrally', 'concept_id': 'C0205099', 'confidence': 0.7070305943489075}, {'entity': 'nucleus', 'concept_id': 'C0007610', 'confidence': 1.0}, {'entity': 'gastric xanthoma', 'concept_id': 'C1282522', 'confidence': 1.0}], [{'entity': 'CD68', 'concept_id': 'C0108799', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'xanthoma', 'concept_id': 'C0302314', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_875",
"caption_rating": "7"
},
{
"": "1008816",
"caption": "The hamartoma involves both the epithelial component and a fibrous sheath around the hair follicle.",
"image_path": "LlPaENuqzVQ_image_0b19780d-498f-43a1-90f3-f4bfc4ead6d3.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['miniaturized hair follicle', 'mantle zone', 'stem cell area', 'bulge', 'apocrine gland', 'sebaceous gland', 'hamartoma', 'fibrous sheath', 'miniaturized hair follicle', 'mantle zone', 'stem cell area', 'bulge', 'apocrine gland', 'sebaceous gland', 'hamartoma', 'fibrous sheath']",
"noisy_text": " Like, it looks more like if there's, if I'm going to guess, like there's, I feel like there's a little bit of like, I would guess more like towards the, like a glandular. Yeah, well, it's, it's, it's a little miniaturized hair follicle. Nope. It's like this little guy here. It's like a little tiny follicle. And there's, we always think of three parts of the hair follicle. We think of the infundibulum, the isthmus, and we think of the inferior portion, but there's a very important part right around the isthmic part, just beneath the follicle, the infundibulum, and then where the inferior portion begins, that's known as the mantle zone. And that's kind of where all the action is. That's really kind of a stem cell area that sometimes those cells will form a little bulge there and they actually will end up forming an apocrine gland. Sometimes they'll end up forming a sebaceous gland. Sometimes they, you know, will just, they'll form, sometimes they form a little hammertoma, like you see right here. And they actually end up getting you this little sort of primitive little, it almost looks like a mini hair follicle that didn't really form. And then when you look at a hair follicle, it's comprised not only of the epithelial component, but there's also a periepithelial sheath around it, a fibrous sheath around the hair follicle. And so this is a hammertoma that involves both of those. So it's got a fibrous element to it. And then",
"corrected_text": " Like, it looks more like if there's, if I'm going to guess, like there's, I feel like there's a little bit of like, I would guess more like towards the, like a glandular. Yeah, well, it's, it's, it's a little miniaturized hair follicle. Nope. It's like this little guy here. It's like a little tiny follicle. And there's, we always think of three parts of the hair follicle. We think of the infundibulum, the isthmus, and we think of the inferior portion, but there's a very important part right around the isthmic part, just beneath the follicle, the infundibulum, and then where the inferior portion begins, that's known as the mantle zone. And that's kind of where all the action is. That's really kind of a stem cell area that sometimes those cells wiform a little bulge there and they actually wiend up forming an apocrine gland. Sometimes they'end up forming a sebaceous gland. Sometimes they, you know, will just, they'form, sometimes they form a little hamartoma, like you see right here. And they actually end up getting you this little sort of primitive little, it almost looks like a mini hair follicle that didn't really form. And then when you look at a hair follicle, it's comprised not only of the epithelial component, but there's also a periepithelial sheath around it, a fibrous sheath around the hair follicle. And so this is a hamartoma that involves both of those. So it's got a fibrous element to it. And then",
"med_umls_ids": "[[{'entity': 'narrator', 'concept_id': 'C1135957', 'confidence': 0.7711340188980103}, {'entity': 'miniaturized', 'concept_id': 'C0872350', 'confidence': 0.8111259341239929}, {'entity': 'hair follicle', 'concept_id': 'C0221971', 'confidence': 1.0}, {'entity': 'stem cell', 'concept_id': 'C0038250', 'confidence': 1.0}, {'entity': 'mantle zone', 'concept_id': 'C1512987', 'confidence': 1.0}], [{'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'mantle', 'concept_id': 'C0232445', 'confidence': 0.8497024178504944}, {'entity': 'zone', 'concept_id': 'C1710706', 'confidence': 1.0}, {'entity': 'bulge', 'concept_id': 'C0038999', 'confidence': 0.9999999403953552}, {'entity': 'apocrine gland', 'concept_id': 'C0003584', 'confidence': 0.9999998807907104}, {'entity': 'sebaceous gland', 'concept_id': 'C0036505', 'confidence': 1.0}, {'entity': 'hamartoma', 'concept_id': 'C0018552', 'confidence': 0.9999999403953552}], [{'entity': 'hamartoma', 'concept_id': 'C0018552', 'confidence': 0.9999999403953552}, {'entity': 'epithelial component', 'concept_id': 'C1707933', 'confidence': 0.8783122897148132}, {'entity': 'fibrous sheath', 'concept_id': 'C1185724', 'confidence': 1.0}, {'entity': 'hair follicle', 'concept_id': 'C0221971', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_876",
"caption_rating": "8"
},
{
"": "1007598",
"caption": "MART1 and HMB45 are usually not present in pure desmoplastic melanomas.",
"image_path": "jCw_NtnS6XU_image_17f9e3d0-66e6-4107-9054-53b31d3f5587.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " on this side we have S100 striking staining throughout the dermis and on this side, those atypical spindle cells are totally negative for MART1. All you see there are a couple little nests. This one had a tiny, tiny component that was nested as well as a melanoma in situ component. That part stained with MART1. The rest of the lesion was totally negative and just stained with S100. So this is a great example to help explain that you're usually not going to have MART1 and HMB45. Those specific markers are not gonna usually be present in pure desmoplastic melanomas. I wanted to show you a comparison. We looked at",
"corrected_text": " on this side we have S100 striking staining throughout the dermis and on this side, those atypical spindle cells are totally negative for MART1. All you see there are a couple little nests. This one had a tiny, tiny component that was nested as well as a melanoma in situ component. That part stained with MART1. The rest of the lesion was totally negative and just stained with S100. So this is a great example to help explain that you're usually not going to have MART1 and HMB45. Those specific markers are not gonna usually be present in pure desmoplastic melanomas. I wanted to show you a comparison. We looked at",
"med_umls_ids": "[[{'entity': 'S100', 'concept_id': 'C3273837', 'confidence': 1.0}, {'entity': 'staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'side', 'concept_id': 'C0441987', 'confidence': 1.0}, {'entity': 'atypical', 'concept_id': 'C0205182', 'confidence': 1.0}, {'entity': 'spindle cells', 'concept_id': 'C0682540', 'confidence': 1.0}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'MART1', 'concept_id': 'C1334510', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'melanoma', 'concept_id': 'C0025202', 'confidence': 1.0}, {'entity': 'in situ component', 'concept_id': 'C1882484', 'confidence': 0.7850481271743774}, {'entity': 'stained', 'concept_id': 'C2986582', 'confidence': 1.0}, {'entity': 'MART1', 'concept_id': 'C1334510', 'confidence': 1.0}], [{'entity': 'MART1', 'concept_id': 'C1334510', 'confidence': 1.0}, {'entity': 'HMB45', 'concept_id': 'C1440756', 'confidence': 1.0}, {'entity': 'desmoplastic', 'concept_id': 'C1511789', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_877",
"caption_rating": "9"
},
{
"": "1008599",
"caption": "Description of a segment with a lamina propria that is pretty devoid of inflammatory cells.",
"image_path": "sDFjOtMAYrk_image_87eda8ad-6e79-47c1-a274-11131c97a2ea.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['lamina propria', 'inflammatory cells', 'eosinophils', 'lymphocytes', 'plasma cells', 'basement membrane', 'lamina propria', 'inflammatory cells', 'eosinophils', 'lymphocytes', 'plasma cells', 'basement membrane']",
"noisy_text": " segment and shows a lamina propria pretty devoid of... You see a couple of inflammatory cells here and there, but not really a lot in the way of lymphocytes, plasma cells, and actually eos are rare. But when you get biopsies, and I'm sorry I didn't bring one from... That was on the left. If you used to have something from the right, your lamina propria is typically busier, and I allow for quite a few eosinophils, lymphocytes, and plasma cells. The other thing that you want to keep in mind is... Let me just go back to the H and E for a second. The basement membrane, I will",
"corrected_text": " segment and shows a lamina propria pretty devoid of... You see a couple of inflammatory cells here and there, but not really a lot in the way of lymphocytes, plasma cells, and actually eos are rare. But when you get biopsies, and I'm sorry I didn't bring one from... That was on the left. If you used to have something from the right, your lamina propria is typically busier, and I allow for quite a few eosinophils, lymphocytes, and plasma cells. The other thing that you want to keep in mind is... Let me just go back to the H and E for a second. The basement membrane, I will",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'segment', 'concept_id': 'C0441635', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'inflammatory cells', 'concept_id': 'C0440752', 'confidence': 1.0}], [{'entity': 'Lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'right', 'concept_id': 'C0205090', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_878",
"caption_rating": "8"
},
{
"": "1006541",
"caption": "Inclusion bodies in myofibroblasts are characteristic of infantile myofibromatosis digital fibroma or infantile digital myofibromatosis.",
"image_path": "8S4LeiO6Bbk_image_12f7026e-e42a-4d49-9ff3-0d7b7d1c886a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['inclusion bodies', 'myofibroblasts', 'myofibroblasts', 'inclusion bodies', 'myofibroblasts']",
"noisy_text": " cell. These, of course, are collections of muscle fibers or muscle filaments. These are myofibroblasts, and these inclusion bodies will stain with actin. They'll also stain red with a trichinome stain and purple with a PTAH stain. These cells, as I indicated, are myofibroblasts. The constellation of findings here is characteristic and pathognomonic of infantile digital fibroma or infantile digital myofibromatosis. Patients may have one or many lesions, and these can actually, if they're present in large enough number, be deforming. This also goes by the name inclusion body fibromatosis, and if you ever see it on a pick list, what you want to do is go down on high power and look for the inclusions. This is kind of a high-power recognition diagnosis, but high yield. Just a beautiful example. We don't see biopsies very often of this condition. Slide number 11. Again, kind of switching gears here. We have a",
"corrected_text": " cell. These, of course, are collections of muscle fibers or muscle filaments. These are myofibroblasts, and these inclusion bodies will stain with actin. They'll also stain red with a trichrome stain and purple with a PTAH stain. These cells, as I indicated, are myofibroblasts. The constellation of findings here is characteristic and pathognomonic of infantile digital fibroma or infantile digital myofibromatosis. Patients may have one or many lesions, and these can actually, if they're present in large enough number, be deforming. This also goes by the name inclusion body fibromatosis, and if you ever see it on a pick list, what you want to do is go down on high power and look for the inclusions. This is kind of a high-power recognition diagnosis, but high yield. Just a beautiful example. We don't see biopsies very often of this condition. Slide number 11. Again, kind of switching gears here. We have a",
"med_umls_ids": "[[{'entity': 'Inclusion bodies', 'concept_id': 'C0007637', 'confidence': 1.0}, {'entity': 'myofibroblasts', 'concept_id': 'C0225360', 'confidence': 1.0}, {'entity': 'infantile myofibromatosis digital fibroma', 'concept_id': 'C0206648', 'confidence': 0.8650985956192017}, {'entity': 'infantile', 'concept_id': 'C0231330', 'confidence': 1.0}], [{'entity': 'cells stain', 'concept_id': 'C0007584', 'confidence': 0.7767881155014038}, {'entity': 'actin', 'concept_id': 'C0001271', 'confidence': 1.0}, {'entity': 'trichrome stain', 'concept_id': 'C0077066', 'confidence': 1.0}, {'entity': 'PTAH stain', 'concept_id': 'C0404079', 'confidence': 0.6286439299583435}], [{'entity': 'Patients', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'lesions', 'concept_id': 'C0221198', 'confidence': 1.0}, {'entity': 'deforming', 'concept_id': 'C0333067', 'confidence': 1.0}, {'entity': 'numbers', 'concept_id': 'C0237753', 'confidence': 1.0}], [{'entity': 'Inclusion body fibromatosis', 'concept_id': 'C1318562', 'confidence': 0.9999999403953552}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_879",
"caption_rating": "9"
},
{
"": "1005836",
"caption": "Multiple deep shaves or excisional/incisional biopsy described.",
"image_path": "LlPaENuqzVQ_image_3897d7c3-22c9-460e-a0dd-32bf7153b6af.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " All right, who wants to give this one a go? Hello, can you hear me? Yeah. Looks like we have multiple deep shaves. Well, wait a second. You've been in the surgery clinic before and you've done a lot of biopsies in your long career now. So this, you think it's really a shave? I take that back. It's probably excision or incisional biopsy. Yeah, yeah, yes, good. This is an excision. So they basically took the elliptical excision. They cut it into bread loaves and put it all on one slide. So that's how",
"corrected_text": " All right, who wants to give this one a go? Hello, can you hear me? Yeah. Looks like we have multiple deep shaves. Well, wait a second. You've been in the surgery clinic before and you've done a lot of biopsies in your long career now. So this, you think it's really a shave? I take that back. It's probably excision or incisional biopsy. Yeah, yeah, yes, good. This is an excision. So they basically took the elliptical excision. They cut it into bread loaves and put it all on one slide. So that's how",
"med_umls_ids": "[[{'entity': 'Multiple', 'concept_id': 'C0439064', 'confidence': 1.0}, {'entity': 'deep shaves', 'concept_id': 'C0518505', 'confidence': 0.7456271648406982}, {'entity': 'excisional/incisional biopsy', 'concept_id': 'C0184921', 'confidence': 0.7826999425888062}], [{'entity': 'Elliptical excision', 'concept_id': 'C1707902', 'confidence': 0.8901858329772949}, {'entity': 'bread', 'concept_id': 'C0006138', 'confidence': 1.0}, {'entity': 'histological examination', 'concept_id': 'C0019637', 'confidence': 0.9535407423973083}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_880",
"caption_rating": "8"
},
{
"": "1004388",
"caption": "Description of normal colonic glands and crypts with no lymphocytes, plasma cells, or eosinophils. The amount of lamina propria in between the crypts is the same as you move from one crypt to another.",
"image_path": "sDFjOtMAYrk_image_f2e3425b-1cb0-4c39-aafa-b9f580a4a0fa.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['colonic crypts', 'muscularis mucosa', 'lamina propria']",
"noisy_text": " fellows about normal. What I like to see are these colonic glands. Do we have an arrow? Oh, yes. It should. Is he not coming up? No. Oh, you have to turn it on. No, it's not coming up. Yeah, it is. Yeah, here you go. Just the red one. Yeah. Oh, I don't see it. It's okay. Is the mouse going to work? Yeah, I'll do the mouse. Yeah, it works. Okay. Basically, I like to see my colonic crypts nice and straight coming from the surface, trying to kiss that muscularis mucosa underneath in between the crypts and the muscularis mucosa. I don't want to see any lymphocytes, plasma cells, eosinophils. You can have one or two. That's okay, but typically no basal lymphoplasma cytosis. The other thing I like to point out is the amount of lamina propria in between the crypts is the same as you move from one crypt to another. The crypts stand equidistant one from another. Remember the differences between the cecum or the right colon and the left colon. This is a biopsy from the segment and shows",
"corrected_text": " fellows about normal. What I like to see are these colonic glands. Do we have an arrow? Oh, yes. It should. Is he not coming up? No. Oh, you have to turn it on. No, it's not coming up. Yeah, it is. Yeah, here you go. Just the red one. Yeah. Oh, I don't see it. It's okay. Is the mouse going to work? Yeah, I'll do the mouse. Yeah, it works. Okay. Basically, I like to see my colonic crypts nice and straight coming from the surface, trying to kiss that muscularis mucosa underneath in between the crypts and the muscularis mucosa. I don't want to see any lymphocytes, plasma cells, eosinophils. You can have one or two. That's okay, but typically no basal lymphoplasma cytosis. The other thing I like to point out is the amount of lamina propria in between the crypts is the same as you move from one crypt to another. The crypts stand equidistant one from another. Remember the differences between the cecum or the right colon and the left colon. This is a biopsy from the segment and shows",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'colonic glands', 'concept_id': 'C0227351', 'confidence': 0.8191195130348206}, {'entity': 'crypts', 'concept_id': 'C0227427', 'confidence': 0.9071587324142456}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'amount', 'concept_id': 'C1265611', 'confidence': 0.9999998807907104}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'crypts', 'concept_id': 'C0227427', 'confidence': 0.9071587324142456}, {'entity': 'crypt', 'concept_id': 'C1880192', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_881",
"caption_rating": "9"
},
{
"": "1006345",
"caption": "Well-defined nerve fascicles with spindle-shaped cells, which are positive with S100 and SOX10, defining the diagnosis of rudimentary supernumerary digit.",
"image_path": "8S4LeiO6Bbk_image_89afc7b2-8d75-4b3c-9eff-ab85550d9c16.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['nerve fascicles', 'spindle-shaped cells', 'rudimentary supernumerary digit', 'ulnar aspect of the fifth digit', 'acquired digital fibroma', 'acquired digital fibrokeratoma', 'trichilemmal cyst', 'nerve fascicles', 'spindle-shaped cells', 'rudimentary supernumerary digit', 'ulnar aspect of the fifth digit', 'acquired digital fibroma', 'acquired digital fibrokeratoma', 'trichilemmal cyst']",
"noisy_text": " core here we've got several well-defined nerve fascicles and the spindled cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions of course tend to occur along the ulnar eye aspect of the fifth digit. They're not infrequently bilateral and the key differential here of course is an acquired digital fibroma or an acquired digital fibrocarotoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if",
"corrected_text": " core here we've got several well-defined nerve fascicles and the spindle cells characterizing these nerve fascicles have the attributes that we associated with neural tumors. Very delicate kind of spindled and s-shaped or somewhat comma-shaped nuclei that are tapered on both ends. These cells of course would be positive with S100 and SOX10 and their presence is defining for this process and the diagnosis in this case is a rudimentary supernumerary digit. These lesions of course tend to occur along the ulnar eye aspect of the fifth digit. They're not infrequently bilateral and the key differential here of course is an acquired digital fibroma or an acquired digital fibrokeratoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if",
"med_umls_ids": "[[{'entity': 'Well-defined nerve fascicles', 'concept_id': 'C1185741', 'confidence': 0.5682494640350342}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'S100', 'concept_id': 'C3273837', 'confidence': 1.0}, {'entity': 'SOX10', 'concept_id': 'C1420317', 'confidence': 0.9999998807907104}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'rudimentary supernumerary digit', 'concept_id': 'C0152427', 'confidence': 0.8142021894454956}], [{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'ulnar', 'concept_id': 'C0442044', 'confidence': 1.0}, {'entity': 'aspect', 'concept_id': 'C1547011', 'confidence': 1.0}, {'entity': 'fifth digit', 'concept_id': 'C0230403', 'confidence': 0.912693440914154}, {'entity': 'bilateral', 'concept_id': 'C0238767', 'confidence': 1.0}], [{'entity': 'differential diagnosis', 'concept_id': 'C0011906', 'confidence': 1.0}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}, {'entity': 'digital fibroma', 'concept_id': 'C4538745', 'confidence': 0.8997364640235901}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}], [{'entity': 'Trichilemmal cyst', 'concept_id': 'C2266788', 'confidence': 1.0}, {'entity': 'biopsy specimen', 'concept_id': 'C0677862', 'confidence': 1.0}, {'entity': 'slide number', 'concept_id': 'C3828004', 'confidence': 0.8261933326721191}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_882",
"caption_rating": "8"
},
{
"": "1004818",
"caption": "Presence of lymphocytes and hints of duct formation within the tumor.",
"image_path": "8S4LeiO6Bbk_image_a0d9ca4b-d2c9-43b5-be52-eea868bbd3fd.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['epithelial tumor', 'cytoplasm', 'vesicular chromatin pattern', 'lymphocytes', 'duct formation', 'epithelial tumor', 'cytoplasm', 'vesicular chromatin pattern', 'lymphocytes', 'duct formation']",
"noisy_text": " If we move to higher power, we can see that we're dealing with an epithelial rather than a mosaicable tumor. We've got interconnected cords and strands. We have somewhat of a ribiform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of the cells are round to oval. They're fairly large. These cells have some faint eosinophilic to pale gray cytoplasm, although this cytoplasm is kind of difficult to see. Some of these cells have an evenly dispersed or vesicular chromatin pattern, and other nuclei are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and",
"corrected_text": " If we move to higher power, we can see that we're dealing with an epithelial rather than a mesenchymal tumor. We've got interconnected cords and strands. We have somewhat of a cribriform pattern here, and these are associated with a very loose, somewhat edematous, and vascular stroma, a lot of vessels here. As we move to higher power and begin to look at this cytologic makeup of these epithelial islands, we can see that we've got at least two cell types here. The nuclei comprising most of the cells are round to oval. They're fairly large. These cells have some faint eosinophilic to pale gray cytoplasm, although this cytoplasm is kind of difficult to see. Some of these cells have an evenly dispersed or vesicular chromatin pattern, and other nuclei are a little bit darker staining, but these two dark and light staining cells are about the same size. And then sprinkled throughout the tumor, there are several lymphocytes, and these lymphocytes of course have a smaller nuclei and little discernible cytoplasm. And then if you looked in areas, you could see hints of duct formation within this tumor, and this constellation of findings, the overall configuration, blue balls in the dermis, two cell types, light and dark staining, and",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'epithelial tumor', 'concept_id': 'C1368683', 'confidence': 0.9999999403953552}, {'entity': 'cords', 'concept_id': 'C0034869', 'confidence': 0.801885187625885}, {'entity': 'strands', 'concept_id': 'C0600383', 'confidence': 0.800572395324707}], [{'entity': 'Cribriform pattern', 'concept_id': 'C1333163', 'confidence': 1.0}, {'entity': 'loose', 'concept_id': 'C0205407', 'confidence': 1.0}, {'entity': 'edematous', 'concept_id': 'C0013604', 'confidence': 1.0}, {'entity': 'vascular stroma', 'concept_id': 'C0005847', 'confidence': 0.8046398758888245}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'cell types', 'concept_id': 'C0007634', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'eosinophilic', 'concept_id': 'C0333930', 'confidence': 1.0}, {'entity': 'pale', 'concept_id': 'C0030232', 'confidence': 1.0}, {'entity': 'gray cytoplasm', 'concept_id': 'C0010834', 'confidence': 0.8177905678749084}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'duct', 'concept_id': 'C0687028', 'confidence': 1.0}, {'entity': 'formation', 'concept_id': 'C0220781', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_883",
"caption_rating": "8"
},
{
"": "1008774",
"caption": "Histopathological description of a targetoid hemosiderotic hemangioma, which can be distinguished from Kaposi\u2019s sarcoma by the absence of plasma cells within the infiltrate and negative HHV8 stain.",
"image_path": "8S4LeiO6Bbk_image_c7ac005f-eb5f-4749-92d4-23438c675a85.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['collagen bundles', 'pre-existing vascular spaces', 'plump endothelial cells', 'absence of plasma cells', 'negative HHV8 stain', 'collagen bundles', 'pre-existing vascular spaces', 'plump endothelial cells', 'absence of plasma cells', 'negative HHV8 stain', 'collagen bundles', 'pre-existing vascular spaces', 'plump endothelial cells', 'absence of plasma cells', 'negative HHV8 stain']",
"noisy_text": " between collagen bundles. We even have a little bit of a promontory sign here where we've got these vessels surrounding pre-existing vascular spaces. But unlike the neovascular spaces that we see in Kaposi's sarcoma, the endothelial cells here are a little more plump, and we don't have plasma cells within the infiltrate. And plasma cells within the infiltrate can be very useful in discriminating between this condition and Kaposi's sarcoma. In this particular case, also the HHV8 stain was a negative, which would be positive in Kaposi's sarcoma. So the diagnosis in this case was a targetoid hemocidiotic hemangioma, sometimes known as a hobnail hemangioma. Frequently has a characteristic clinical appearance, occurs commonly",
"corrected_text": " between collagen bundles. We even have a little bit of a promontory sign here where we've got these vessels surrounding pre-existing vascular spaces. But unlike the neovascularization that we see in Kaposi's sarcoma, the endothelial cells here are a little more plump, and we don't have plasma cells within the infiltrate. And plasma cells within the infiltrate can be very useful in discriminating between this condition and Kaposi's sarcoma. In this particular case, also the HHV8 stain was a negative, which would be positive in Kaposi's sarcoma. So the diagnosis in this case was a targetoid hemosiderotic hemangioma, sometimes known as a hobnail hemangioma. Frequently has a characteristic clinical appearance, occurs commonly",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'targetoid hemosiderotic hemangioma', 'concept_id': 'C0346076', 'confidence': 0.9999999403953552}, {'entity': 'Kaposi\u2019s sarcoma', 'concept_id': 'C0036220', 'confidence': 0.9617650508880615}, {'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}]]",
"magnification": "1.0",
"height": "758.0",
"width": "1920.0",
"id": "test_884",
"caption_rating": "9"
},
{
"": "1004881",
"caption": "Discussion of inflammatory disease patterns and the presence of neutrophils.",
"image_path": "LlPaENuqzVQ_image_ba9f5053-3223-4223-ac28-b10ba5f32bd8.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['spongiosis in the epidermis', 'spongiosis in the epidermis', 'hair follicle', 'neutrophils']",
"noisy_text": " Over here, what pattern are we looking at? Here, it looks more mixed. But remember, there's one other pattern in the nine major patterns of inflammatory disease. What are we looking at here? Well, that looks kind of like... Oh, I see what you're saying. Yeah, it looks like there's more spongiosis in the epidermis. Like there's... I don't know if this is like a pastoral... What's this thing? A hair follicle, or where you might... Yeah, it's a hair follicle. That's probably also a hair follicle. It's probably just off to the side of it a little bit. And so what have we got here? It looks like a lot of neutrophils. Yeah, you got",
"corrected_text": " Over here, what pattern are we looking at? Here, it looks more mixed. But remember, there's one other pattern in the nine major patterns of inflammatory disease. What are we looking at here? Well, that looks kind of like... Oh, I see what you're saying. Yeah, it looks like there's more spongiosis in the epidermis. Like there's... I don't know if this is like a pastoral... What's this thing? A hair follicle, or where you might... Yeah, it's a hair follicle. That's probably also a hair follicle. It's probably just off to the side of it a little bit. And so what have we got here? It looks like a lot of neutrophils. Yeah, you got",
"med_umls_ids": "[[{'entity': 'inflammatory disease', 'concept_id': 'C1290884', 'confidence': 0.9999999403953552}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_885",
"caption_rating": "8"
},
{
"": "1004247",
"caption": "Muscularization of the lamina propria is a criterion for mucosal prolapse.",
"image_path": "r7OA0Trj5hQ_image_e281e036-beef-4673-b94e-a2e73f4043c9.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['muscle', 'lamina propria', 'muscularis mucosa', 'chemical gastritis', 'mucosal prolapse', 'solitary rectal ulcer syndrome', 'muscle', 'lamina propria', 'muscularis mucosa', 'chemical gastritis', 'mucosal prolapse', 'solitary rectal ulcer syndrome']",
"noisy_text": " You see in the hyperwire, muscle coming in the lamina propria. Lamina propria should be free of musculature. The muscle should be there only in the muscularis mucosa. Here in this low power, you can see the muscularis mucosa is hyperplastic. And it is sending the muscle bundle into the lamina propria. This happens in chemical gastritis in case of stomach and in cases of mucosal prolapse in colon. Remember that solitary rectal ulcer syndrome, which is totally misnomer. It is neither solitary, can be seen in other parts other than rectum. There may not be any ulcer, there is no syndrome. So the whole solitary rectal ulcer syndrome is a misnomer. But muscularization of the lamina propria is one of the criteria for mucosal prolapse that is happening in",
"corrected_text": " You see in the hyperplasia, muscle coming in the lamina propria. Lamina propria should be free of musculature. The muscle should be there only in the muscularis mucosa. Here in this low power, you can see the muscularis mucosa is hyperplastic. And it is sending the muscle bundle into the lamina propria. This happens in chemical gastritis in case of stomach and in cases of mucosal prolapse in colon. Remember that solitary rectal ulcer syndrome, which is totally misnomer. It is neither solitary, can be seen in other parts other than rectum. There may not be any ulcer, there is no syndrome. So the whole solitary rectal ulcer syndrome is a misnomer. But muscularization of the lamina propria is one of the criteria for mucosal prolapse that is happening in",
"med_umls_ids": "[[{'entity': 'Muscle hyperplasia', 'concept_id': 'C2265913', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'abnormal', 'concept_id': 'C0205161', 'confidence': 1.0}, {'entity': 'muscularis mucosa', 'concept_id': 'C0225357', 'confidence': 0.9999998807907104}], [{'entity': 'Muscle bundles', 'concept_id': 'C0504095', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'hyperplasia', 'concept_id': 'C0020507', 'confidence': 1.0}, {'entity': 'muscularis mucosa', 'concept_id': 'C0225357', 'confidence': 0.9999998807907104}], [{'entity': 'Muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'criterion', 'concept_id': 'C0243161', 'confidence': 1.0}, {'entity': 'mucosal prolapse', 'concept_id': 'C0034888', 'confidence': 0.826268196105957}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_886",
"caption_rating": "9"
},
{
"": "1006523",
"caption": "Relatively normal lung tissue with evidence of collapse in some areas.",
"image_path": "jF_pj4-tEC8_image_a8748cfc-eb79-497b-87a1-78f6ea5ac243.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Pulmonary', 'Cardiac', 'Gastrointestinal']",
"roi_text": "['asthma', 'lung tissue', 'evidence of collapse']",
"noisy_text": " is from that young person who had a history of asthma, went to the ER, the ER doctor gave him some asthmatic medicine and he went on and still wasn't feeling well, so the patient came back and collapsed and died in the parking lot of the ER department, and they tried to resuscitate him, but they couldn't, but anyway, I want to show you that this is relatively normal lung tissue as I peruse around, and I'm going to show you some of the findings. Now, some of it, like you see in this area right here, there is some evidence of collapse or atelectasis,",
"corrected_text": " is from that young person who had a history of asthma, went to the ER, the ER doctor gave him some asthmatic medicine and he went on and still wasn't feeling well, so the patient came back and collapsed and died in the parking lot of the ER department, and they tried to resuscitate him, but they couldn't, but anyway, I want to show you that this is relatively normal lung tissue as I peruse around, and I'm going to show you some of the findings. Now, some of it, like you see in this area right here, there is some evidence of collapse or atelectasis,",
"med_umls_ids": "[[{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'history of', 'concept_id': 'C0262926', 'confidence': 0.9999999403953552}, {'entity': 'asthma', 'concept_id': 'C0004096', 'confidence': 1.0}, {'entity': 'collapsed', 'concept_id': 'C0344329', 'confidence': 1.0}, {'entity': 'died', 'concept_id': 'C0011065', 'confidence': 1.0}, {'entity': 'parking lot', 'concept_id': 'C0442639', 'confidence': 1.0}, {'entity': 'ER department', 'concept_id': 'C1547116', 'confidence': 0.9239601492881775}], [{'entity': 'lung tissue', 'concept_id': 'C0819757', 'confidence': 1.0}, {'entity': 'evidence', 'concept_id': 'C3887511', 'confidence': 1.0}, {'entity': 'collapse', 'concept_id': 'C0036974', 'confidence': 1.0}, {'entity': 'areas', 'concept_id': 'C0205146', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "608.0",
"id": "test_887",
"caption_rating": "7"
},
{
"": "1004412",
"caption": "Neural hypertrophy may indicate Crohn's disease.",
"image_path": "r7OA0Trj5hQ_image_391ca795-2aab-4b66-9f24-6486937d85d6.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['neural hypertrophy', 'ganglion cells', 'submucosa', 'congenital megacolon', 'submucosa']",
"noisy_text": " for example, carotid endoartrectomy or abdominal aortic encephalopathy, that history is very important for cholesterol emboli. Here, there is more like a neural hypertrophy. Whenever you see neural hypertrophy, you have to think of Crohn's disease. Here, you see the ganglion cells in the submicosa. When you see ganglion cells, these are normal component of the submicosa. And why I am showing it, sometimes you may think of malignancy. Here, you may not think of it. And another point, these are all the cells we are looking in congenital mecagola. So if you don't see them in the submicosa in frozen section, again, this will qualify for congenital mecagola. Here, another tricky thing. This is",
"corrected_text": " for example, carotid endarterectomy or abdominal aortic encephalopathy, that history is very important for cholesterol emboli. Here, there is more like a neural hypertrophy. Whenever you see neural hypertrophy, you have to think of Crohn's disease. Here, you see the ganglion cells in the submucosa. When you see ganglion cells, these are normal component of the submucosa. And why I am showing it, sometimes you may think of malignancy. Here, you may not think of it. And another point, these are all the cells we are looking in congenital megacolon. So if you don't see them in the submucosa in frozen section, again, this will qualify for congenital megacolon. Here, another tricky thing. This is",
"med_umls_ids": "[[{'entity': 'History', 'concept_id': 'C0019664', 'confidence': 1.0}, {'entity': 'carotid endarterectomy', 'concept_id': 'C0014099', 'confidence': 1.0}, {'entity': 'abdominal aortic encephalopathy', 'concept_id': 'C0507867', 'confidence': 0.6308470964431763}, {'entity': 'cholesterol emboli', 'concept_id': 'C0149649', 'confidence': 0.8653062582015991}], [{'entity': 'Neural hypertrophy', 'concept_id': 'C0020564', 'confidence': 0.8345715999603271}, {'entity': \"Crohn's disease\", 'concept_id': 'C0010346', 'confidence': 1.0}], [{'entity': 'Ganglion cells', 'concept_id': 'C0228071', 'confidence': 1.0}, {'entity': 'submucosa', 'concept_id': 'C0225344', 'confidence': 1.0}, {'entity': 'malignancy', 'concept_id': 'C0006826', 'confidence': 1.0}], [{'entity': 'Ganglion cells', 'concept_id': 'C0228071', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'congenital megacolon', 'concept_id': 'C0019569', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_888",
"caption_rating": "8"
},
{
"": "1004969",
"caption": "Increased number of melanocytes within the matrix epithelium is diagnostic of melanoma in situ involving the nail unit.",
"image_path": "8S4LeiO6Bbk_image_a554fb42-fe7d-476d-8134-63ca39eff646.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Biopsy specimen', 'Bottom piece of tissue', 'Melanocytes present within the matrix epithelium', 'Consumption of the matrix epithelium', 'Confluence of pagetoid scatter', 'Biopsy specimen', 'Bottom piece of tissue', 'Melanocytes present within the matrix epithelium', 'Consumption of the matrix epithelium', 'Confluence of pagetoid scatter']",
"noisy_text": " biopsy specimen, the tissue in question, I'm going to rotate the slide a little bit. And what we want to focus on is the bottom piece of tissue. Again, remember this was a biopsy of matricle epithelium and you can see there's a marked increase in the number of melanocytes present within the matricle epithelium. All of these brown staining cells are melanocytes and you can see we've almost got consumption of the matricle epithelium. There in areas are really more melanocytes than there are matricle keratinocytes. And this confluence of pagetoid scatter is diagnostic of melanoma in situ involving the nail unit. One could also use a SOX10 stain, which is a nuclear melanocytic stain, sometimes a little bit cleaner than the MART1 stain, which is a cytoplasmic stain. So first case, slides one",
"corrected_text": " biopsy specimen, the tissue in question, I'm going to rotate the slide a little bit. And what we want to focus on is the bottom piece of tissue. Again, remember this was a biopsy of matrix epithelium and you can see there's a marked increase in the number of melanocytes present within the matrix epithelium. All of these brown staining cells are melanocytes and you can see we've almost got consumption of the matrix epithelium. There in areas are really more melanocytes than there are matrix keratinocytes. And this confluence of pagetoid scatter is diagnostic of melanoma in situ involving the nail unit. One could also use a SOX10 stain, which is a nuclear melanocytic stain, sometimes a little bit cleaner than the MART1 stain, which is a cytoplasmic stain. So first case, slides one",
"med_umls_ids": "[[{'entity': 'Increased', 'concept_id': 'C0205217', 'confidence': 1.0}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'matrix epithelium', 'concept_id': 'C0014609', 'confidence': 0.7584323883056641}, {'entity': 'diagnostic', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'melanoma', 'concept_id': 'C0025202', 'confidence': 1.0}, {'entity': 'in situ', 'concept_id': 'C0444498', 'confidence': 0.9999999403953552}, {'entity': 'nail unit', 'concept_id': 'C4758673', 'confidence': 0.8730567693710327}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_889",
"caption_rating": "9"
},
{
"": "1006657",
"caption": "Large vascular channels in the chorion filled with blood.",
"image_path": "PJX3uZ7fRn4_image_04826078-6f5b-4030-b6cf-ae91c50d42bc.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gynecologic', 'Soft tissue', 'Hematopathology']",
"roi_text": "['vascular channels', 'chorionic villi', 'calcification']",
"noisy_text": " This is a section from placenta which shows a large irregular area with proliferation of thin walled vascular channels of variable size towards the fetal surface of placenta. Smaller chorionic villi can be seen towards the maternal site. Higher magnification of the same showing large vascular channels in the chorion filled with blood. Still higher magnification showing intercommunicating slit-like vascular spaces in the mass. Focal area of calcification can be seen in the tumor. Still another area",
"corrected_text": " This is a section from placenta which shows a large irregular area with proliferation of thin walled vascular channels of variable size towards the fetal surface of placenta. smaller chorionic villi are not incorrect can be seen towards the maternal site. Higher magnification of the same showing large vascular channels in the chorion filled with blood. Still higher magnification showing intercommunicating slit-like vascular spaces in the mass. Focal area of calcification can be seen in the tumor. Still another area",
"med_umls_ids": "[[{'entity': 'Proliferation', 'concept_id': 'C0334094', 'confidence': 1.0}, {'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}, {'entity': 'variable size', 'concept_id': 'C1866144', 'confidence': 0.8559831976890564}, {'entity': 'fetal', 'concept_id': 'C0015965', 'confidence': 1.0}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'placenta', 'concept_id': 'C0032043', 'confidence': 1.0}], [{'entity': 'chorionic villi', 'concept_id': 'C0008508', 'confidence': 1.0}, {'entity': 'maternal site', 'concept_id': 'C0026591', 'confidence': 0.7640593647956848}], [{'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}, {'entity': 'chorion', 'concept_id': 'C0008503', 'confidence': 0.9999998807907104}, {'entity': 'blood', 'concept_id': 'C0005767', 'confidence': 1.0}], [{'entity': 'Intercommunicating', 'concept_id': 'C0205196', 'confidence': 0.8271207213401794}, {'entity': 'vascular spaces', 'concept_id': 'C0225983', 'confidence': 0.819495439529419}, {'entity': 'mass', 'concept_id': 'C0577559', 'confidence': 1.0}], [{'entity': 'Focal area', 'concept_id': 'C0205234', 'confidence': 0.7634891271591187}, {'entity': 'calcification', 'concept_id': 'C0006660', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_890",
"caption_rating": "7"
},
{
"": "1006537",
"caption": "Scattered dyskeratotic cells within the basal layer.",
"image_path": "8S4LeiO6Bbk_image_24e7ef9f-fdec-4317-a973-ebbc11a14881.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['superficial perivascular infiltrate', 'epidermis', 'basement of the rete ridge pattern', 'basal cell change along the DEJ', 'dyskeratotic cells within the basal layer', 'papillary dermis']",
"noisy_text": " Moving on to slide number eight. Slide number eight is the first of two interface dermatitis that we're going to be looking at. This is a bisected punch biopsy from the trunk or proximal extremity. Get that down and in this specimen we can see that we've got a superficial perivascular infiltrate present within the dermis. We've clearly got evidence of some epidural change here. The epidermis is quite thin, the basement of the Reedy ridge pattern. We have a basket we've cornified layer but as we zoom in we can see that we've got pronounced bacular change along the DEJ, scattered dyskeratotic cells within the basal layer, and within the papillary dermis we have a",
"corrected_text": " Moving on to slide number eight. Slide number eight is the first of two interface dermatitis that we're going to be looking at. This is a bisected punch biopsy from the trunk or proximal extremity. Get that down and in this specimen we can see that we've got a superficial perivascular infiltrate present within the dermis. We've clearly got evidence of some epidural change here. The epidermis is quite thin, the basement of the rete ridge pattern. We have a basket we've cornified layer but as we zoom in we can see that we've got pronounced basal cell change along the DEJ, scattered dyskeratotic cells within the basal layer, and within the papillary dermis we have a",
"med_umls_ids": "[[{'entity': 'punch biopsy', 'concept_id': 'C0182557', 'confidence': 1.0}, {'entity': 'trunk', 'concept_id': 'C0225442', 'confidence': 0.9999999403953552}, {'entity': 'proximal extremity', 'concept_id': 'C0015385', 'confidence': 0.745482325553894}], [{'entity': 'Superficial', 'concept_id': 'C0205124', 'confidence': 1.0}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}], [{'entity': 'Evidence', 'concept_id': 'C3887511', 'confidence': 1.0}, {'entity': 'epidural change', 'concept_id': 'C0228134', 'confidence': 0.7621071338653564}], [{'entity': 'Thin epidermis', 'concept_id': 'C4231265', 'confidence': 1.0}, {'entity': 'basement', 'concept_id': 'C0085872', 'confidence': 0.772655725479126}, {'entity': 'rete', 'concept_id': 'C0010306', 'confidence': 0.7033917903900146}, {'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}], [{'entity': 'basal cell', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'DEJ', 'concept_id': 'C0385794', 'confidence': 0.5962325930595398}], [{'entity': 'Scattered', 'concept_id': 'C0439742', 'confidence': 1.0}, {'entity': 'dyskeratotic cells', 'concept_id': 'C1512098', 'confidence': 0.8970272541046143}, {'entity': 'basal layer', 'concept_id': 'C0221925', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_891",
"caption_rating": "8"
},
{
"": "1008515",
"caption": "The histological picture of endodermal sinus tumor shows Schiller-Duval-Dewall bodies, which are specialized bodies that comprise a central capillary surrounded by tumor cells.",
"image_path": "3mRB9j0eyVM_image_93b859d1-6fae-4171-93a6-905bac877aae.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gynecologic', 'Hematopathology', 'Soft tissue']",
"roi_text": "['Schiller-Duval-Dewall bodies in endodermal sinus tumor', 'lymphatics in dysgerminoma', 'glomerulite structure of endodermal sinus tumor']",
"noisy_text": " Then other malignant young cell tumors include the yolk sap tumor that is highly malignant. It is also named as endodermal sinus tumor. It affects the young age and these are partly solid and they secrete alpha-phetoprotein. This is my dear student the histological picture of yolk sap tumor. The typical finding of yolk sap tumor is that it contains the specialized type of bodies that are named as Shiller-Dewall bodies. That Shiller-Dewall bodies are the bodies that comprise of the central capillary, central this vascular area and it is surrounded by the tumor cells. Then a space and that space is again surrounded by the tumor cells. So it presents as the glomerulite structure like glomerulus like that is just like as the as we see the glomerulus of a kidney. So glomerulite bodies that are found and that are typical of the yolk sap tumor and these glomerulite bodies are named as Shiller-Dewall bodies. So these are the typical identification feature of the yolk sap. Then is the dysgerminoma that is very common highly malignant tumor and usually it spreads by lymphatics. It is very radio",
"corrected_text": " Then other malignant young cell tumors include the endodermal sinus tumor that is highly malignant. It is also named as endodermal sinus tumor. It affects the young age and these are partly solid and they secrete alpha-fetoprotein. This is my dear student the histological picture of endodermal sinus tumor. The typical finding of endodermal sinus tumor is that it contains the specialized type of bodies that are named as Schiller-Duval-Dewall bodies. That Schiller-Duval-Dewall bodies are the bodies that comprise of the central capillary, central this vascular area and it is surrounded by the tumor cells. Then a space and that space is again surrounded by the tumor cells. So it presents as the glomerulite structure like glomerulus like that is just like as the as we see the glomerulus of a kidney. So glomerulite bodies that are found and that are typical of the endodermal sinus tumor and these glomerulite bodies are named as Schiller-Duval-Dewall bodies. So these are the typical identification feature of the yolk sap. Then is the dysgerminoma that is very common highly malignant tumor and usually it spreads by lymphatics. It is very radio",
"med_umls_ids": "[[{'entity': 'Endodermal sinus tumor', 'concept_id': 'C0014145', 'confidence': 1.0}, {'entity': 'malignant tumor', 'concept_id': 'C0006826', 'confidence': 1.0}, {'entity': 'young', 'concept_id': 'C0332239', 'confidence': 1.0}, {'entity': 'individuals', 'concept_id': 'C0027361', 'confidence': 0.8766164779663086}, {'entity': 'solid', 'concept_id': 'C0205208', 'confidence': 1.0}, {'entity': 'secretes', 'concept_id': 'C1327616', 'confidence': 0.8702053427696228}, {'entity': 'alpha-fetoprotein', 'concept_id': 'C0002210', 'confidence': 1.0}], [{'entity': 'histological picture', 'concept_id': 'C0205462', 'confidence': 0.785039484500885}, {'entity': 'endodermal sinus tumor', 'concept_id': 'C0014145', 'confidence': 1.0}, {'entity': 'Schiller-Duval-Dewall bodies', 'concept_id': 'C1710022', 'confidence': 0.7228695750236511}, {'entity': 'bodies', 'concept_id': 'C0242821', 'confidence': 1.0}, {'entity': 'central capillary surrounded', 'concept_id': 'C0006901', 'confidence': 0.5871620774269104}, {'entity': 'tumor cells', 'concept_id': 'C0431085', 'confidence': 1.0}], [{'entity': 'Dysgerminoma', 'concept_id': 'C0013377', 'confidence': 1.0}, {'entity': 'malignant tumor', 'concept_id': 'C0006826', 'confidence': 1.0}, {'entity': 'spreads', 'concept_id': 'C0564319', 'confidence': 0.8124106526374817}, {'entity': 'lymphatics', 'concept_id': 'C0024235', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "960.0",
"id": "test_892",
"caption_rating": "9"
},
{
"": "1008658",
"caption": "Histopathological examination of prostate cancer with staining for nuclear and membranous wispy cytoplasmic stain, hemoglobin cytokeratin, and predominantly negative racemase.",
"image_path": "iklRyY1nBIE_image_5b8f5755-469f-46e1-8e9d-ec523e502284.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['Prostate cancer with aberrant P63 staining expression.', 'Prostate cancer with aberrant P63 staining expression.']",
"noisy_text": " Again, you want to look at your internal control. These are the glands that were comfortable or benign. You can see they're staining for both nuclear stain and membranous wispy cytoplasmic stain, which is the hemoglobin cytokeratin. In this baccalaureate case, the racemase was predominantly negative. There's a hint of staining in areas, but it's predominantly negative. What is striking, what is very striking, is the fact that the P63 is diffusely positive, which they found very odd. And so this is a very, very fascinating case of prostatic adenocarcinoma with aberrant P63 expression, or what some people call P63 prostate prostate cancer. And I'll show you, this is the index case, but I'll show you a few other cases. Because it's a very, very fascinating, it's an",
"corrected_text": " Again, you want to look at your internal control. These are the glands that were comfortable or benign. You can see they're staining for both nuclear stain and membranous wispy cytoplasmic stain, which is the hemoglobin cytokeratin. In this baccalaureate case, the racemase was predominantly negative. There's a hint of staining in areas, but it's predominantly negative. What is striking, what is very striking, is the fact that the P63 is diffusely positive, which they found very odd. And so this is a very, very fascinating case of prostatic adenocarcinoma with aberrant P63 expression, or what some people call P63 prostate prostate cancer. And I'll show you, this is the index case, but I'll show you a few other cases. Because it's a very, very fascinating, it's an",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'examination', 'concept_id': 'C0031809', 'confidence': 1.0}, {'entity': 'prostate cancer', 'concept_id': 'C0376358', 'confidence': 1.0}, {'entity': 'staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'nuclear', 'concept_id': 'C0521447', 'confidence': 1.0}, {'entity': 'membranous', 'concept_id': 'C0025255', 'confidence': 1.0}, {'entity': 'wispy cytoplasmic stain', 'concept_id': 'C0010834', 'confidence': 0.6738394498825073}, {'entity': 'hemoglobin cytokeratin', 'concept_id': 'C0010803', 'confidence': 0.7460406422615051}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'racemase', 'concept_id': 'C0034503', 'confidence': 1.0}], [{'entity': 'Diffuse positive P63 staining', 'concept_id': 'C0205219', 'confidence': 0.5406208634376526}, {'entity': 'expression', 'concept_id': 'C0017262', 'confidence': 0.9999998807907104}, {'entity': 'prostatic adenocarcinoma', 'concept_id': 'C0007112', 'confidence': 1.0}, {'entity': 'P63 prostate cancer', 'concept_id': 'C0376358', 'confidence': 0.7053087949752808}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_893",
"caption_rating": "7"
},
{
"": "1007990",
"caption": "The cornified layer appears thickened in this case.",
"image_path": "8S4LeiO6Bbk_image_d97bcf0a-d765-4958-8e41-b1c9ecc2bb83.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Thickened cornified layer', 'Slightly thinned epidermis with a basement of the reed bridge pattern', 'Uniform spindle-shaped cells in the dermis with elongated and tapered nuclei and indistinct cytoplasmic margins', 'Crisscross configuration of fascicles throughout the dermis']",
"noisy_text": " kind of relegated to do in this case, we can see that the cornified layer is somewhat thickened. This biopsy was from near an acral surface. This was from the finger. You can see that the epidermis is slightly thinned with the basement of the reed bridge pattern, and then filling the dermis in this case, we have fascicles of uniform spindle-shaped cells. You can see that their nuclei are elongated and tapered. The cytoplasmic margins of these cells are somewhat indistinct. They do have somewhat elongated cytoplasmic processes, and there are a range of fascicles. Some of the fascicles are cut in cross-section. Here you can see the nuclei appear more round. Some are cut longitudinally, and that's where we see the very elongated nuclei and cytoplasmic processes, and some are cut tangentially. This gives these fascicles kind of a crisscross configuration throughout the dermis. Hopefully, you all were able to pick up on the diagnostic feature in",
"corrected_text": " kind of relegated to do in this case, we can see that the cornified layer is somewhat thickened. This biopsy was from near an acral surface. This was from the finger. You can see that the epidermis is slightly thinned with the basement of the reed bridge pattern, and then filling the dermis in this case, we have fascicles of uniform spindle-shaped cells. You can see that their nuclei are elongated and tapered. The cytoplasmic margins of these cells are somewhat indistinct. They do have somewhat elongated cytoplasmic processes, and there are a range of fascicles. Some of the fascicles are cut in cross-section. Here you can see the nuclei appear more round. Some are cut longitudinally, and that's where we see the very elongated nuclei and cytoplasmic processes, and some are cut tangentially. This gives these fascicles kind of a crisscross configuration throughout the dermis. Hopefully, you all were able to pick up on the diagnostic feature in",
"med_umls_ids": "[[{'entity': 'cornified layer', 'concept_id': 'C3554359', 'confidence': 0.8562335968017578}, {'entity': 'thickened', 'concept_id': 'C0205400', 'confidence': 1.0}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}], [{'entity': 'epidermis', 'concept_id': 'C0014520', 'confidence': 1.0}, {'entity': 'thinned', 'concept_id': 'C0392758', 'confidence': 1.0}, {'entity': 'basement', 'concept_id': 'C0085872', 'confidence': 0.772655725479126}, {'entity': 'reed', 'concept_id': 'C0681191', 'confidence': 0.7412400841712952}], [{'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'fascicles', 'concept_id': 'C1185741', 'confidence': 1.0}, {'entity': 'uniform', 'concept_id': 'C0205375', 'confidence': 1.0}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}, {'entity': 'elongated', 'concept_id': 'C0205166', 'confidence': 1.0}, {'entity': 'tapered', 'concept_id': 'C0441640', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'indistinct cytoplasmic margins', 'concept_id': 'C4323148', 'confidence': 0.6683960556983948}], [{'entity': 'fascicles', 'concept_id': 'C1185741', 'confidence': 1.0}, {'entity': 'crisscross configuration', 'concept_id': 'C0449830', 'confidence': 0.7424066066741943}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_894",
"caption_rating": "8"
},
{
"": "1008537",
"caption": "Partial atrophy is characterized by partially atrophic glands that may be cystically dilated and have varying amounts of cytoplasm.",
"image_path": "iklRyY1nBIE_image_d679d1b5-2f4a-40aa-9aa0-e29634b90e37.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['Glands with patchy basal positivity', 'Partially atrophic glands with varying cytoplasm and cystic dilation']",
"noisy_text": " The problem is when we come to this area we were looking at earlier, you can see that some of the glands show patchy positivity for the basal cell markers, but some of them are completely negative. And to complicate things even more, some of these glands are positive for racemase or amarkar, so-called amarkar, and that causes a lot of concern. So that's why they were struggling with this case, because if you see positive racemase expression, which is typically positive in cancer, and you see negative basal cell expression, the impression people have is that you're dealing with cancer. But that's not always the case, and that's why I'm sharing this case with all of you, because this is actually a process called partial atrophy. The glands I showed you on H&E are partially atrophic. You can still see some of it here. Some of them are cystically dilated here. In some areas you can see more cytoplasm. In other areas it looks more atrophic. So even on this paint cocktail, you can appreciate the partially atrophic features. So this is a benign process. You should not call this cancer, and you should not be too generous with your atypical diagnosis either, or some people call it atypical small atrial proliferation. You should not render that diagnosis too frequently, otherwise your clinical colleagues won't trust your histologic judgment. So one has to be very careful with that. One should use that term very sparingly. So this is partial atrophy, and it's not unusual to have this kind of picture. If all the glands show patchy basal positivity, then that makes it an easy case. But some cases are tricky like this one, where some of the glands are completely negative for basal cell markers, while others are patchy positive for basal cell markers. But once you recognize on the H and E that both, you know, all these glands have similar cytologic features, both in the nucleus and the cytoplasm, that should make your life very easy. So this was a very good case of partial atrophy. I have some other cases I'll share with you very quickly. Similar scenario,",
"corrected_text": " The problem is when we come to this area we were looking at earlier, you can see that some of the glands show patchy positivity for the basal cell markers, but some of them are completely negative. And to complicate things even more, some of these glands are positive for racemase or AMACR, so-called AMACR, and that causes a lot of concern. So that's why they were struggling with this case, because if you see positive racemase expression, which is typically positive in cancer, and you see negative basal cell expression, the impression people have is that you're dealing with cancer. But that's not always the case, and that's why I'm sharing this case with all of you, because this is actually a process called partial atrophy. The glands I showed you on H&E are partially atrophic. You can still see some of it here. Some of them are cystically dilated here. In some areas you can see more cytoplasm. In other areas it looks more atrophic. So even on this paint cocktail, you can appreciate the partially atrophic features. So this is a benign process. You should not call this cancer, and you should not be too generous with your atypical diagnosis either, or some people call it atypical small atrial proliferation. You should not render that diagnosis too frequently, otherwise your clinical colleagues won't trust your histologic judgment. So one has to be very careful with that. One should use that term very sparingly. So this is partial atrophy, and it's not unusual to have this kind of picture. If all the glands show patchy basal positivity, then that makes it an easy case. But some cases are tricky like this one, where some of the glands are completely negative for basal cell markers, while others are patchy positive for basal cell markers. But once you recognize on the H and E that both, you know, all these glands have similar cytologic features, both in the nucleus and the cytoplasm, that should make your life very easy. So this was a very good case of partial atrophy. I have some other cases I'share with you very quickly. Similar scenario,",
"med_umls_ids": "[[{'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'area', 'concept_id': 'C0017446', 'confidence': 1.0}, {'entity': 'patchy', 'concept_id': 'C0205413', 'confidence': 1.0}, {'entity': 'positivity', 'concept_id': 'C4280732', 'confidence': 0.8599872589111328}, {'entity': 'basal cell', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'markers', 'concept_id': 'C0181734', 'confidence': 0.890313982963562}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'cancer', 'concept_id': 'C0006826', 'confidence': 0.9999998807907104}, {'entity': 'benign process', 'concept_id': 'C0205183', 'confidence': 0.7677057981491089}, {'entity': 'partial', 'concept_id': 'C0728938', 'confidence': 1.0}, {'entity': 'atrophy', 'concept_id': 'C0333641', 'confidence': 1.0}], [{'entity': 'Partial atrophy', 'concept_id': 'C1265892', 'confidence': 1.0}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'atrophic glands', 'concept_id': 'C5194745', 'confidence': 0.8184286952018738}, {'entity': 'cystically', 'concept_id': 'C0205207', 'confidence': 0.6787945628166199}, {'entity': 'dilated', 'concept_id': 'C0700124', 'confidence': 0.9999999403953552}, {'entity': 'cytoplasm', 'concept_id': 'C0010834', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_895",
"caption_rating": "9"
},
{
"": "1006364",
"caption": "The observed area shows extensive necrosis and bad-looking cells. There is a debate about the grading of the case, which is not a prostate primary. PSA stain shows positive results for benign glands, while GATA3 shows opposite expression with negative results for internal control glands.",
"image_path": "iklRyY1nBIE_image_69d04319-ecfd-4722-a1d4-852d5776ef51.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " So let's just look at the different areas. This area looks very, very busy. Lots of bad-looking cells, necrosis, extensive necrosis. So this case, this case we're looking at right now, one of the issues was how to grade it. Is this 549 or 459? Some of you would argue that's the midpoint, because they're both grade group 5. But I've seen those kind of scenarios before where there's a debate about grade, because the assumption has been made that it's a prostate primary. But in this case, as you'll see shortly, this is actually a different term. That's not what's going on with this case. So let's take a look at some of the stains. So this is PSA. You can see the benign glands are positive. The other glands and cells that are of interest are completely negative, completely negative. So you can see these are some more benign prostate glands that are positive there. The other stain that was done in this case was a GATA3. And you see it's the opposite expression. So the internal control glands are negative for GATA3, and the",
"corrected_text": " So let's just look at the different areas. This area looks very, very busy. Lots of bad-looking cells, necrosis, extensive necrosis. So this case, this case we're looking at right now, one of the issues was how to grade it. Is this 549 or 459? Some of you would argue that's the midpoint, because they're both grade group 5. But I've seen those kind of scenarios before where there's a debate about grade, because the assumption has been made that it's a prostate primary. But in this case, as you'll see shortly, this is actually a different term. That's not what's going on with this case. So let's take a look at some of the stains. So this is PSA. You can see the benign glands are positive. The other glands and cells that are of interest are completely negative, completely negative. So you can see these are some more benign prostate glands that are positive there. The other stain that was done in this case was a GATA3. And you see it's the opposite expression. So the internal control glands are negative for GATA3, and the",
"med_umls_ids": "[[{'entity': 'area', 'concept_id': 'C0017446', 'confidence': 1.0}, {'entity': 'necrosis', 'concept_id': 'C0027540', 'confidence': 1.0}, {'entity': 'grading', 'concept_id': 'C0441800', 'confidence': 0.9999999403953552}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'prostate primary', 'concept_id': 'C1335512', 'confidence': 0.7813769578933716}, {'entity': 'PSA', 'concept_id': 'C0138741', 'confidence': 1.0}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'results', 'concept_id': 'C0456984', 'confidence': 0.8586957454681396}, {'entity': 'benign glands', 'concept_id': 'C1301287', 'confidence': 0.726940393447876}, {'entity': 'GATA3', 'concept_id': 'C1307598', 'confidence': 1.0}, {'entity': 'expression', 'concept_id': 'C0017262', 'confidence': 0.9999998807907104}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'results', 'concept_id': 'C0456984', 'confidence': 0.8586957454681396}, {'entity': 'internal control glands', 'concept_id': 'C0597937', 'confidence': 0.7678565979003906}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_896",
"caption_rating": "7"
},
{
"": "1009109",
"caption": "The tumor is a variation of low-grade fibromyxoid sarcoma, which can be confused with the neuroblastoma-like variant of schwannoma.",
"image_path": "QDb68_G1HR4_image_85c0ccc4-360e-44bc-84d0-3c033ab285e7.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Big collagen rich rosettes', 'Prominent round cell appearance around the edge of the rim of the nodules', 'Small round blue cells of a neuroblastoma']",
"noisy_text": " It has also big collagen rich rosettes like this but it has a much more prominent round cell appearance around the edge of the rim of the nodules are very like small round blue cell almost look a little bit like the small round blue cells of a neuroblastoma which is why it's named that way but I've definitely seen pathologists have trouble telling those two apart telling a hyalinizing spindle cell tumor with giant rosettes. This tumor we're looking at here a variation of low-grade fibromyxoid sarcoma I've seen people get that confused with the neuroblastoma-like variant of schwannoma and the difference is important because the schwannoma is even though the name sounds kind of scary is actually benign it has a small round blue cell appearance but it's totally benign variation of schwannoma. S100 should easily solve that problem because S100 would be negative here in low-grade fibromyxoid sarcoma and",
"corrected_text": " It has also big collagen rich rosettes like this but it has a much more prominent round cell appearance around the edge of the rim of the nodules are very like small round blue cell almost look a little bit like the small round blue cells of a neuroblastoma which is why it's named that way but I've definitely seen pathologists have trouble telling those two apart telling a hyalinizing spindle cell tumor with giant rosettes. This tumor we're looking at here a variation of low-grade fibromyxoid sarcoma I've seen people get that confused with the neuroblastoma-like variant of schwannoma and the difference is important because the schwannoma is even though the name sounds kind of scary is actually benign it has a small round blue cell appearance but it's totally benign variation of schwannoma. S100 should easily solve that problem because S100 would be negative here in low-grade fibromyxoid sarcoma and",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'rosettes', 'concept_id': 'C0035863', 'confidence': 0.8847858905792236}, {'entity': 'round cell', 'concept_id': 'C0487470', 'confidence': 1.0}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'edge', 'concept_id': 'C0205154', 'confidence': 1.0}, {'entity': 'rim', 'concept_id': 'C1308727', 'confidence': 1.0}, {'entity': 'nodules', 'concept_id': 'C0028259', 'confidence': 1.0}, {'entity': 'neuroblastoma', 'concept_id': 'C0027819', 'confidence': 1.0}], [{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'variation', 'concept_id': 'C0205419', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'neuroblastoma-like variant of', 'concept_id': 'C1419295', 'confidence': 0.6589864492416382}, {'entity': 'schwannoma', 'concept_id': 'C0027809', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_897",
"caption_rating": "9"
},
{
"": "1005442",
"caption": "Moderate amount of amphiphilic cytoplasm.",
"image_path": "j_rG5XPImFQ_image_6da69d48-a359-4580-bf7d-0ccdf5b83e5b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Hematopathology', 'Breast pathology']",
"roi_text": "['nucleolus', 'myofibroblasts', 'myositis ossificans']",
"noisy_text": " nucleolus, and a moderate amount of amphiphilic cytoplasm. Now, at first glance, you might think these cells look a bit weird, and that might make you worry about a sarcoma, such as osteosarcoma. However, you'll come to recognize that this pattern in morphology you see here is really characteristic of myofibroblasts. This is an example of myocytosocificans, a benign myofibroblastic neoplasm that is part of the USP6 rearranged family of tumors, which includes, among others, nodular fasciitis and aneurysmal bone cyst. These are",
"corrected_text": " nucleolus, and a moderate amount of amphiphilic cytoplasm. Now, at first glance, you might think these cells look a bit weird, and that might make you worry about a sarcoma, such as osteosarcoma. However, you'll come to recognize that this pattern in morphology you see here is really characteristic of myofibroblasts. This is an example of myositis ossificans, a benign myofibroblastic neoplasm that is part of the USP6 rearranged family of tumors, which includes, among others, nodular fasciitis and aneurysmal bone cyst. These are",
"med_umls_ids": "[[{'entity': 'Moderate', 'concept_id': 'C0205081', 'confidence': 1.0}, {'entity': 'amount', 'concept_id': 'C1265611', 'confidence': 0.9999998807907104}, {'entity': 'amphiphilic', 'concept_id': 'C0596084', 'confidence': 0.8564908504486084}, {'entity': 'cytoplasm', 'concept_id': 'C0010834', 'confidence': 1.0}], [{'entity': 'Characteristic', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}, {'entity': 'myofibroblasts', 'concept_id': 'C0225360', 'confidence': 1.0}], [{'entity': 'Myositis ossificans', 'concept_id': 'C0027122', 'confidence': 0.9999999403953552}, {'entity': 'benign', 'concept_id': 'C0205183', 'confidence': 1.0}, {'entity': 'USP6', 'concept_id': 'C1175888', 'confidence': 1.0}, {'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_898",
"caption_rating": "8"
},
{
"": "1008739",
"caption": "Prominent nucleoli are seen in the cells, but the NC ratio is overall low.",
"image_path": "sDFjOtMAYrk_image_9c82fad4-2cd4-46e7-ad2a-ea44f4a70f53.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['prominent nucleoli', 'reactive cytologic atypia', 'chemotherapy or radiation', 'cancer', 'inflammatory bowel disease', 'prominent nucleoli', 'reactive cytologic atypia', 'chemotherapy or radiation', 'cancer', 'inflammatory bowel disease', 'prominent nucleoli', 'reactive cytologic atypia', 'chemotherapy or radiation', 'cancer', 'inflammatory bowel disease']",
"noisy_text": " I'm missing it. Okay. I think what's catching my eye for the most part is the prominent nucleolide, but what would you say about the NC ratio? Yeah, I think overall it's low. You have lots, loads of cytoplasm. Even though the nuclei are big, you have loads of cytoplasm. So, with this morphology, first of all, the question was, you know, inflammatory bowel disease. Okay, maybe, but the cytology is not great for the degree of reactive epithelial changes. Although you can have some crazy looking inflammatory bowel disease cases, it's really crazy. When I see crazy bizarre epithelial atypia, I think about treatment effect, either chemotherapy or radiation. Both of them can give you this crazy cytologic atypia that sometimes may actually make you think of cancer. We've got a couple of cases received in consultation. I'm remembering one specifically in the stomach where the question is, what about this cancer? And it wasn't. It was just crazy reactive epithelial changes in a patient who we didn't know, but the patient had received radiotherapy for lung cancer. And it definitely looked a lot like malignancy, but there was something not right about it. So, this patient was receiving at the same time chemotherapy for his pancreatic cancer. One thing you can see in patients, especially when they're receiving radiation,",
"corrected_text": " I'm missing it. Okay. I think what's catching my eye for the most part is the prominent nucleoli, but what would you say about the NC ratio? Yeah, I think overall it's low. You have lots, loads of cytoplasm. Even though the nuclei are big, you have loads of cytoplasm. So, with this morphology, first of all, the question was, you know, inflammatory bowel disease. Okay, maybe, but the cytology is not great for the degree of reactive epithelial changes. Although you can have some crazy looking inflammatory bowel disease cases, it's really crazy. When I see crazy bizarre epithelial atypia, I think about treatment effect, either chemotherapy or radiation. Both of them can give you this reactive cytologic atypia that sometimes may actually make you think of cancer. We've got a couple of cases received in consultation. I'm remembering one specifically in the stomach where the question is, what about this cancer? And it wasn't. It was just crazy reactive epithelial changes in a patient who we didn't know, but the patient had received radiotherapy for lung cancer. And it definitely looked a lot like malignancy, but there was something not right about it. So, this patient was receiving at the same time chemotherapy for his pancreatic cancer. One thing you can see in patients, especially when they're receiving radiation,",
"med_umls_ids": "[[{'entity': 'Prominent', 'concept_id': 'C0205402', 'confidence': 0.9999999403953552}, {'entity': 'nucleoli', 'concept_id': 'C0007609', 'confidence': 0.8710004091262817}, {'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'NC', 'concept_id': 'C0027964', 'confidence': 1.0}, {'entity': 'ratio', 'concept_id': 'C0456603', 'confidence': 1.0}, {'entity': 'low', 'concept_id': 'C0205251', 'confidence': 0.9999999403953552}], [{'entity': 'Reactive cytologic atypia', 'concept_id': 'C0333865', 'confidence': 0.8587049245834351}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'treatment effect', 'concept_id': 'C1518681', 'confidence': 1.0}, {'entity': 'chemotherapy', 'concept_id': 'C0013216', 'confidence': 1.0}, {'entity': 'radiation', 'concept_id': 'C0034519', 'confidence': 1.0}], [{'entity': 'Crazy', 'concept_id': 'C0424157', 'confidence': 0.6988691687583923}, {'entity': 'cancer', 'concept_id': 'C0006826', 'confidence': 0.9999998807907104}], [{'entity': 'Inflammatory bowel disease', 'concept_id': 'C0021390', 'confidence': 1.0}, {'entity': 'cytology', 'concept_id': 'C0010818', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_899",
"caption_rating": "8"
},
{
"": "1007838",
"caption": "Presence of internal elastic lamina indicates artery, while its absence indicates vein.",
"image_path": "r7OA0Trj5hQ_image_369996bb-284b-4e9e-bf1b-4a1517fa0710.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " In high power, you can see very thick vessel wall with the narrowing of the lumen, whereas here, it is relatively preserved. So you want to know whether it is a vein or artery. Please believe me, this is a vein, and this is an artery. And that is proved by the elastic tissue strain. These are all pictures from Dr. Gonzalez's Twitter. And you can see here, there is no internal elastic lamina, whereas here, there is an internal elastic lamina. So this is a branch of mesenteric artery, whereas this is a branch of mesenteric vein. And there is a condition called as idiopathic myointimal hyperplasia of the mesenteric vein. I don't know how many of you have heard this company. There's a",
"corrected_text": " In high power, you can see very thick vessel wall with the narrowing of the lumen, whereas here, it is relatively preserved. So you want to know whether it is a vein or artery. Please believe me, this is a vein, and this is an artery. And that is proved by the elastic tissue strain. These are all pictures from Dr. Gonzalez's Twitter. And you can see here, there is no internal elastic lamina, whereas here, there is an internal elastic lamina. So this is a branch of mesenteric artery, whereas this is a branch of mesenteric vein. And there is a condition called as idiopathic myointimal hyperplasia of mesenteric vein of the mesenteric vein. I don't know how many of you have heard this company. There's a",
"med_umls_ids": "[[{'entity': 'Thick vessel wall', 'concept_id': 'C1180033', 'confidence': 0.6420797109603882}, {'entity': 'lumen', 'concept_id': 'C0524461', 'confidence': 0.9999998807907104}, {'entity': 'power', 'concept_id': 'C0032863', 'confidence': 1.0}], [{'entity': 'Identification', 'concept_id': 'C0020792', 'confidence': 1.0}, {'entity': 'vein', 'concept_id': 'C0042449', 'confidence': 1.0}, {'entity': 'artery', 'concept_id': 'C0003842', 'confidence': 1.0}, {'entity': 'elastic tissue', 'concept_id': 'C0013762', 'confidence': 1.0}, {'entity': 'strain', 'concept_id': 'C0080194', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'internal elastic lamina', 'concept_id': 'C1180561', 'confidence': 1.0}, {'entity': 'artery', 'concept_id': 'C0003842', 'confidence': 1.0}, {'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'vein', 'concept_id': 'C0042449', 'confidence': 1.0}], [{'entity': 'Branches', 'concept_id': 'C1182977', 'confidence': 0.7288598418235779}, {'entity': 'mesenteric artery', 'concept_id': 'C0025465', 'confidence': 1.0}, {'entity': 'vein', 'concept_id': 'C0042449', 'confidence': 1.0}, {'entity': 'examples', 'concept_id': 'C1707959', 'confidence': 0.8639216423034668}], [{'entity': 'Idiopathic myointimal hyperplasia', 'concept_id': 'C0333978', 'confidence': 0.8139097094535828}, {'entity': 'mesenteric vein', 'concept_id': 'C0025473', 'confidence': 1.0}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_900",
"caption_rating": "8"
},
{
"": "1009001",
"caption": "The histology of pityriasis lichenoides and pleva is similar, with pleva showing more acute features such as spongiosis, ballooning, and necrosis.",
"image_path": "8S4LeiO6Bbk_image_8babc89a-e6f4-49c9-a23a-79c16fb030c5.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Infiltrate within the dermis composed entirely of lymphocytes.', 'Few extravasated erythrocytes in some areas.', 'Fragmented biopsy specimen with bluish stain.', 'Infiltrate within the dermis composed entirely of lymphocytes.', 'Few extravasated erythrocytes in some areas.']",
"noisy_text": " and if we look at the infiltrate within the dermis, we can see that it's composed entirely of lymphocytes. In some areas, there were a few extravasated erythrocytes, a few of which were carried up into the overlying epidermis. This constellation of findings is most suggestive of pittoriasis liganoides. Clinically, this patient had PLC, or pittoriasis liganoides chronica. I tend to view pittoriasis liganoides as running along a spectrum. A lot of times, we'll refer to the entire spectrum as Leuka Habermann disease, with pittoriasis liganoides chronica being on the one end of the spectrum, and pleva being on the other end of the spectrum, PLC being characterized by more scaly macules or scaly papules, and pleva being characterized by more crusted and eroded papulonecrotic type lesions. But the histology of the two conditions is actually quite similar. It's a matter of degree. With pleva, you're more likely the acute form of the condition to see more spongiosis, ballooning, necrosis, a denser infiltrate, more necrotics along the DEJ, pericaratosis containing neutrophils. With PLC, similar findings, just a little more blunt. The inflammatory infiltrate may be present around the superficial plexus only. One usually can see some pericaratosis, but there aren't as many necrotic keratinocytes along the DEJ, and a lot of times, the alterations within the epidermis are more subtle. But this was an example of biopsy from a patient with clinically documented pittoriasis like in wades clonica. Moving on to slide number 10. This was, I thought, a really cool case. This was a fragmented biopsy specimen, and you can see that the stain is quite bluish. I can't",
"corrected_text": " and if we look at the infiltrate within the dermis, we can see that it's composed entirely of lymphocytes. In some areas, there were a few extravasated erythrocytes, a few of which were carried up into the overlying epidermis. This constellation of findings is most suggestive of pityriasis lichenoides. Clinically, this patient had PLC, or pityriasis lichenoides chronica. I tend to view pityriasis lichenoides as running along a spectrum. A lot of times, we'refer to the entire spectrum as Leuka Habermann disease, with pityriasis lichenoides chronica being on the one end of the spectrum, and pleva being on the other end of the spectrum, PLC being characterized by more scaly macules or scaly papules, and pleva being characterized by more crusted and eroded papulonecrotic type lesions. But the histology of the two conditions is actually quite similar. It's a matter of degree. With pleva, you're more likely the acute form of the condition to see more spongiosis, ballooning, necrosis, a denser infiltrate, more necrotic along the DEJ, parakeratosis containing neutrophils. With PLC, similar findings, just a little more blunt. The inflammatory infiltrate may be present around the superficial plexus only. One usually can see some parakeratosis, but there aren't as many necrotic keratinocytes along the DEJ, and a lot of times, the alterations within the epidermis are more subtle. But this was an example of biopsy from a patient with clinically documented pittoriasis like in chronica. Moving on to slide number 10. This was, I thought, a really cool case. This was a fragmented biopsy specimen, and you can see that the stain is quite bluish. I can't",
"med_umls_ids": "[[{'entity': 'dermal infiltrate', 'concept_id': 'C0332448', 'confidence': 0.8524853587150574}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'extravasated', 'concept_id': 'C0015376', 'confidence': 0.868863582611084}, {'entity': 'erythrocytes', 'concept_id': 'C0014772', 'confidence': 1.0}, {'entity': 'areas', 'concept_id': 'C0205146', 'confidence': 1.0}, {'entity': 'pityriasis', 'concept_id': 'C0032024', 'confidence': 0.9999998807907104}, {'entity': 'lichenoides', 'concept_id': 'C0443248', 'confidence': 0.8475416302680969}], [{'entity': 'Pityriasis lichenoides', 'concept_id': 'C0162853', 'confidence': 1.0}, {'entity': 'running', 'concept_id': 'C0035953', 'confidence': 1.0}, {'entity': 'spectrum', 'concept_id': 'C1883073', 'confidence': 1.0}, {'entity': 'pityriasis lichenoides chronica', 'concept_id': 'C0162851', 'confidence': 1.0}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'scaly macules', 'concept_id': 'C0332573', 'confidence': 0.7616965174674988}, {'entity': 'papules', 'concept_id': 'C0332563', 'confidence': 0.9999999403953552}], [{'entity': 'histology', 'concept_id': 'C0019638', 'confidence': 1.0}, {'entity': 'pityriasis lichenoides', 'concept_id': 'C0162853', 'confidence': 1.0}, {'entity': 'pleva', 'concept_id': 'C0162852', 'confidence': 1.0}, {'entity': 'pleva', 'concept_id': 'C0162852', 'confidence': 1.0}, {'entity': 'acute', 'concept_id': 'C0205178', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'spongiosis', 'concept_id': 'C0702120', 'confidence': 1.0}, {'entity': 'ballooning', 'concept_id': 'C0004704', 'confidence': 1.0}, {'entity': 'necrosis', 'concept_id': 'C0027540', 'confidence': 1.0}], [{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'clinically documented', 'concept_id': 'C1828480', 'confidence': 0.814785361289978}, {'entity': 'pityriasis lichenoides chronica', 'concept_id': 'C0162851', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_901",
"caption_rating": "9"
},
{
"": "1005138",
"caption": "The patient has massive exfoliative dermatitis, which is a condition characterized by widespread scaling and flaking of the skin.",
"image_path": "udoW6VSqsm4_image_30e6f4ea-91ea-4de7-b623-197288c784a5.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['Exfoliative dermatitis']",
"noisy_text": " Pidicarenalysis, yeah, is that what this is? I didn't see any of this. No, this would be the piticarenalysis that ate Cleveland or something. Massive loss of the stratum corneum. It's really big. Those are usually teensy tiny little bells. So, this may not be in your vocabulary. You know, if you don't speak Russian and somebody asks you what's the Russian word for restaurant, you wouldn't know that it looked like pectopaw, you know, when you looked at it the way it was spelled. So, basically, if this isn't in your vocabulary, you don't have any idea what it is. Of course, you would notice that there's loss of the stratum corneum and there's also loss of the greater psoas. Who knows what this is? None of you guys know?",
"corrected_text": " pityriasis, yeah, is that what this is? I didn't see any of this. No, this would be the pityriasis that ate Cleveland or something. Massive loss of the stratum corneum. It's really big. Those are usually teensy tiny little bells. So, this may not be in your vocabulary. You know, if you don't speak Russian and somebody asks you what's the Russian word for restaurant, you wouldn't know that it looked like restaurant, you know, when you looked at it the way it was spelled. So, basically, if this isn't in your vocabulary, you don't have any idea what it is. Of course, you would notice that there's loss of the stratum corneum and there's also loss of the greater omentum. Who knows what this is? None of you guys know?",
"med_umls_ids": "[[{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'massive', 'concept_id': 'C0522501', 'confidence': 1.0}, {'entity': 'exfoliative dermatitis', 'concept_id': 'C0011606', 'confidence': 1.0}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'widespread', 'concept_id': 'C0205219', 'confidence': 1.0}, {'entity': 'scaling', 'concept_id': 'C0237849', 'confidence': 1.0}, {'entity': 'flaking', 'concept_id': 'C1880783', 'confidence': 1.0}, {'entity': 'skin', 'concept_id': 'C0444099', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_902",
"caption_rating": "8"
},
{
"": "1004298",
"caption": "Hyalinized lamina propria may be present in cases of long-standing ischemia.",
"image_path": "sDFjOtMAYrk_image_6186fdd9-5438-4a29-9e87-049df53ff824.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['Superficial injury', 'Bottom crypts', 'Hyalinized lamina propria', 'Cytologic atypia', 'Superficial injury', 'Bottom crypts', 'Hyalinized lamina propria', 'Cytologic atypia']",
"noisy_text": " what you see in patients with ischemia. So basically, injury that's predominantly superficial with relative preservation of the bottom crypts. Very hyaluronized lamina propria when the ischemia has been ongoing for a while. It may or may not be there when the ischemia has been short-lived. Here you can see very nicely the superficial injury with relatively preserved bottoms. I find the cytologic atypia really helpful when I'm dealing with cases where I really don't know what's going on. I've caught maybe one or two cases of patients with subclinical very mild level ischemia that the only finding was just the cytologic atypia that I don't know where it's really coming from. And I'll show a case down the road. Actually, I'll show it right now. So this is a patient who I don't really remember the clinical history. I just thought, I mean, the architecture",
"corrected_text": " what you see in patients with ischemia. So basically, injury that's predominantly superficial with relative preservation of the bottom crypts. Very hyalinized lamina propria when the ischemia has been ongoing for a while. It may or may not be there when the ischemia has been short-lived. Here you can see very nicely the superficial injury with relatively preserved bottoms. I find the cytologic atypia really helpful when I'm dealing with cases where I really don't know what's going on. I've caught maybe one or two cases of patients with subclinical very mild level ischemia that the only finding was just the cytologic atypia that I don't know where it's really coming from. And I'll show a case down the road. Actually, I'll show it right now. So this is a patient who I don't really remember the clinical history. I just thought, I mean, the architecture",
"med_umls_ids": "[[{'entity': 'Superficial injury', 'concept_id': 'C0332671', 'confidence': 1.0}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}], [{'entity': 'Hyalinized lamina propria', 'concept_id': 'C0332230', 'confidence': 0.7577076554298401}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}], [{'entity': 'Cytologic atypia', 'concept_id': 'C0333865', 'confidence': 1.0}, {'entity': 'finding', 'concept_id': 'C0037088', 'confidence': 1.0}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'mild', 'concept_id': 'C1513302', 'confidence': 1.0}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_903",
"caption_rating": "9"
},
{
"": "1005436",
"caption": "Cytokeratin will be positive in signet cell carcinoma.",
"image_path": "r7OA0Trj5hQ_image_61216ada-4856-4a84-bf6e-c6b8466d2f1f.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Gastric xanthoma', 'Signet ring cells', 'Poorly differentiated signet cell carcinoma', 'Gastric xanthoma', 'Signet ring cells', 'Poorly differentiated signet cell carcinoma']",
"noisy_text": " And so this is a gastric xanthoma. Here, it is more like a signet cells. And when you do cytokeratin, it will all be positive. So it's a poorly differentiated signet cell carcinoma. And there are only three types of pathologists in the world. And this, I got it again from Twitter, I think from Sanjay Bhavatiya, pathologists who missed signet cells, pathologists who are missing the signet cells, pathologists who will be missing the signet cell carcinoma. So it's a very, very, very difficult condition. We have to keep our eyes wide. Leave open to",
"corrected_text": " And so this is a gastric xanthoma. Here, it is more like a signet cells. And when you do cytokeratin, it will all be positive. So it's a poorly differentiated signet cell carcinoma. And there are only three types of pathologists in the world. And this, I got it again from Twitter, I think from Sanjay Bhavatiya, pathologists who missed signet cells, pathologists who are missing the signet cells, pathologists who will be missing the signet cell carcinoma. So it's a very, very, very difficult condition. We have to keep our eyes wide. Leave open to",
"med_umls_ids": "[[{'entity': 'Gastric xanthoma', 'concept_id': 'C1282522', 'confidence': 1.0}, {'entity': 'signet cell carcinoma', 'concept_id': 'C0206696', 'confidence': 0.9410539865493774}], [{'entity': 'Cytokeratin', 'concept_id': 'C0010803', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'signet cell carcinoma', 'concept_id': 'C0206696', 'confidence': 0.9410539865493774}], [{'entity': 'Signet cell carcinoma', 'concept_id': 'C0206696', 'confidence': 0.9410539865493774}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_904",
"caption_rating": "8"
},
{
"": "1009235",
"caption": "The presence of darker staining cells at the periphery, along with lymphocytes and scattered plasma cells, suggests the presence of infected histiocytes with small organisms within their cytoplasm.",
"image_path": "hoV-JkD6Wb0_image_09f48c15-1a31-47a5-af78-9211fbd37b30.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['Large histiocytes with cleared out cytoplasm', 'Erythrocyte used as a ruler to measure the size of the organisms']",
"noisy_text": " darker staining cells out at the periphery. And out at the periphery, we have a lot of lymphocytes and several scattered plasma cells. And if we look at the more clear staining areas, we can see that we actually have very large histiocytes. We've cleared out cytoplasm and with a little effort, one could see that there were organisms present within the cytoplasm of these histiocytes producing so-called parasitized histiocytes. And the organisms are very small, one to two microns. And we can use our erythrocyte here as kind of a ruler. Most erythrocytes and lymphocytes have nuclei that have diameters about five to six microns. And so you can see that these round organisms at",
"corrected_text": " darker staining cells out at the periphery. And out at the periphery, we have a lot of lymphocytes and several scattered plasma cells. And if we look at the more clear staining areas, we can see that we actually have very large histiocytes. We've cleared out cytoplasm and with a little effort, one could see that there were organisms present within the cytoplasm of these histiocytes producing so-called parasitized histiocytes. And the organisms are very small, one to two microns. And we can use our erythrocyte here as kind of a ruler. Most erythrocytes and lymphocytes have nuclei that have diameters about five to six microns. And so you can see that these round organisms at",
"med_umls_ids": "[[{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'darker staining cells', 'concept_id': 'C0007600', 'confidence': 0.5783368945121765}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'scattered', 'concept_id': 'C0439742', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'infected', 'concept_id': 'C0439663', 'confidence': 1.0}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'small organisms', 'concept_id': 'C0029235', 'confidence': 0.8106848001480103}, {'entity': 'cytoplasm', 'concept_id': 'C0010834', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_905",
"caption_rating": "9"
},
{
"": "1006183",
"caption": "Normal epithelium, low-grade dysplasia, and high-grade dysplasia can be seen in one picture.",
"image_path": "r7OA0Trj5hQ_image_db9604e5-bd2a-49f1-ba3b-c70944238020.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Back-to-back glands', 'Stroma running in between', 'Crowded appearance', 'Back-to-back glands', 'Cribriform appearance', 'Intraglandular epithelial proliferation']",
"noisy_text": " you can see some stroma running in between. However, it may be crowded. See here, one gland, another gland. You can see the nice stroma in between. These are back-to-back glands. But see here, this is one gland, this is one gland, this is one gland. But no stroma in between. So these are cribriform, which is intraglandular. Epithelial proliferation is happening within the gland, which is a future of high-grade dysplasia. So normal epithelium, low-grade dysplasia, high-grade dysplasia in one picture. Thanks to Google. I don't know the source, but I thank the person, anonymous person. So those are",
"corrected_text": " you can see some stroma running in between. However, it may be crowded. See here, one gland, another gland. You can see the nice stroma in between. These are back-to-back glands. But see here, this is one gland, this is one gland, this is one gland. But no stroma in between. So these are cribriform, which is intraglandular. Epithelial proliferation is happening within the gland, which is a future of high-grade dysplasia. So normal epithelium, low-grade dysplasia, high-grade dysplasia in one picture. Thanks to Google. I don't know the source, but I thank the person, anonymous person. So those are",
"med_umls_ids": "[[{'entity': 'Intraglandular', 'concept_id': 'C4725341', 'confidence': 0.9096097350120544}, {'entity': 'epithelial proliferation', 'concept_id': 'C0334097', 'confidence': 1.0}, {'entity': 'high-grade dysplasia', 'concept_id': 'C1333110', 'confidence': 0.8831341862678528}], [{'entity': 'Normal epithelium', 'concept_id': 'C0014609', 'confidence': 0.8199569582939148}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'dysplasia', 'concept_id': 'C0334044', 'confidence': 1.0}, {'entity': 'high-grade dysplasia', 'concept_id': 'C1333110', 'confidence': 0.8831341862678528}, {'entity': 'picture', 'concept_id': 'C0441468', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_906",
"caption_rating": "8"
},
{
"": "1009356",
"caption": "Molecular testing may be necessary if there are marked pleomorphism, high mitotic activity, or other concerning features.",
"image_path": "QDb68_G1HR4_image_7a59655a-83cd-439d-b918-af37b1dcc063.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " sometimes pleomorphism is seen it's just really uncommon. Also mitotic activity I don't think I mentioned it yet mitoses are usually very very low in this tumor if you see I think the general rule is if you're unless you're a sarcoma pathology expert. And even then if I see even as a sarcoma pathologist if I see marked pleomorphism a lot of mitotic activity other features like that I'm probably going to send the case for molecular testing just to be totally sure that it's a low-grade fiber myxoid sarcoma and not some other mimic. So experts",
"corrected_text": " sometimes pleomorphism is seen it's just really uncommon. Also mitotic activity I don't think I mentioned it yet mitoses are usually very very low in this tumor if you see I think the general rule is if you're unless you're a sarcoma pathology expert. And even then if I see even as a sarcoma pathologist if I see marked pleomorphism a lot of mitotic activity other features like that I'm probably going to send the case for molecular testing just to be totally sure that it's a low-grade fiber myxoid sarcoma and not some other mimic. So experts",
"med_umls_ids": "[[{'entity': 'Pleomorphism', 'concept_id': 'C0032219', 'confidence': 1.0}, {'entity': 'mitotic activity', 'concept_id': 'C1334779', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}], [{'entity': 'Mitoses', 'concept_id': 'C0026255', 'confidence': 1.0}], [{'entity': 'Molecular testing', 'concept_id': 'C1521991', 'confidence': 0.8002516627311707}, {'entity': 'pleomorphism', 'concept_id': 'C0032219', 'confidence': 1.0}, {'entity': 'mitotic activity', 'concept_id': 'C1334779', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_907",
"caption_rating": "8"
},
{
"": "1005796",
"caption": "Fibrin and inflammatory cells in the papillary dermis and blister cavity, with lymphocytes and scattered eosinophils present within the dermis, thickening or retention of the dermal papillae, and lots of eosinophils, extravasated erythrocytes, lymphocytes, and a few neutrophils in the blister cavity. These findings are consistent with bullous pemphigoid (BP), which was confirmed by direct immunofluorescence showing a linear IgG.",
"image_path": "hoV-JkD6Wb0_image_428b00c9-8608-424c-9471-7df53eac4049.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Pediatric', 'Soft tissue']",
"roi_text": "['Inflammatory cells in the papillary dermis and blister cavity', 'Lymphocytes and scattered eosinophils within the dermis', 'Thickening or retention of the dermal papillae', 'Eosinophils, extravasated erythrocytes, lymphocytes, and a few neutrophils in the blister cavity']",
"noisy_text": " There's fibrin and inflammatory cells in the papillary dermis and in the blister cavity. And if we look at the inflammatory infiltrate, there are lymphocytes and scattered eosinophils present within the dermis, some festooning or retention of the dermal papillae, and lots of eosinophils, some extravasated erythrocytes, lymphocytes, and a few neutrophils in the blister cavity. And so, you know, I'm thinking this is pretty good for BP, especially given the clinical presentation. And sure enough, on direct immunofluorescence, there was a linear IgG, and I didn't show that through C3,",
"corrected_text": " There's fibrin and inflammatory cells in the papillary dermis and in the blister cavity. And if we look at the inflammatory infiltrate, there are lymphocytes and scattered eosinophils present within the dermis, some spongiosis or retention of the dermal papillae, and lots of eosinophils, some extravasated erythrocytes, lymphocytes, and a few neutrophils in the blister cavity. And so, you know, I'm thinking this is pretty good for BP, especially given the clinical presentation. And sure enough, on direct immunofluorescence, there was a linear IgG, and I didn't show that through C3,",
"med_umls_ids": "[[{'entity': 'Fibrin', 'concept_id': 'C0015982', 'confidence': 1.0}, {'entity': 'inflammatory cells', 'concept_id': 'C0440752', 'confidence': 1.0}, {'entity': 'papillary dermis', 'concept_id': 'C0682598', 'confidence': 1.0}, {'entity': 'blister', 'concept_id': 'C0005758', 'confidence': 1.0}, {'entity': 'cavity', 'concept_id': 'C0011334', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'scattered', 'concept_id': 'C0439742', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'thickening', 'concept_id': 'C0205400', 'confidence': 1.0}, {'entity': 'retention', 'concept_id': 'C0035280', 'confidence': 1.0}, {'entity': 'dermal', 'concept_id': 'C0221928', 'confidence': 1.0}, {'entity': 'papillae', 'concept_id': 'C4230196', 'confidence': 0.8667760491371155}, {'entity': 'lots', 'concept_id': 'C0302148', 'confidence': 0.7982692718505859}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'extravasated', 'concept_id': 'C0015376', 'confidence': 0.868863582611084}, {'entity': 'erythrocytes', 'concept_id': 'C0014772', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'blister', 'concept_id': 'C0005758', 'confidence': 1.0}, {'entity': 'cavity', 'concept_id': 'C0011334', 'confidence': 1.0}, {'entity': 'findings', 'concept_id': 'C2607943', 'confidence': 1.0}, {'entity': 'consistent with', 'concept_id': 'C0332290', 'confidence': 1.0}, {'entity': 'bullous pemphigoid', 'concept_id': 'C0030805', 'confidence': 0.9999999403953552}, {'entity': 'BP', 'concept_id': 'C0005823', 'confidence': 1.0}, {'entity': 'immunofluorescence', 'concept_id': 'C0016318', 'confidence': 1.0}, {'entity': 'linear IgG.', 'concept_id': 'C0205132', 'confidence': 0.5133615732192993}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_908",
"caption_rating": "10"
},
{
"": "1005167",
"caption": "Low-grade fibromyxoid sarcoma is defined by a translocation, with the most common being the translocation 716 between the FUS and CREB3L2 genes.",
"image_path": "QDb68_G1HR4_image_3173ce40-b11f-40b2-bf84-fa1803725c7e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['synovial sarcoma', 'low-grade fibromyxoid sarcoma', 'FUS gene rearrangement']",
"noisy_text": " but I've seen very rare examples where there were very well differentiated areas in a synovial sarcoma that kind of had a fibrous look and looked similar to low-grade fibromyxoid sarcoma. So in that case, obviously you could use other stains like keratins and if you like TLE1 you could do that. And then in the end, if you have trouble, molecular pathology can help us out. Like I said earlier, these tumors, low-grade fibromyxoid sarcoma is defined by a translocation. The most common translocation is the translocation 716 which is between the genes FUS and CREB3L2. And there's also a small subset of these that have an alternate translocation which is between the FUS gene and the CREB3L1 gene. So FUS-CREB3L2 or FUS-CREB3L1 gene fusion can support the diagnosis. So you could use break apart fish for FUS. If the tumor looks like this and FUS is positive for FUS rearrangement, then you should be pretty good in calling it a low-grade fibromyxoid sarcoma. But do be aware that there are many other tumors in soft tissue pathology that have FUS rearrangements, myxoid liposarcoma and others. They usually have a different histologic appearance. So that's why you can never use, at least in my opinion, you shouldn't use molecular pathology by itself. You have to couple it with the clinical scenario and the histologic features and the immunostain findings. Put",
"corrected_text": " but I've seen very rare examples where there were very well differentiated areas in a synovial sarcoma that kind of had a fibrous look and looked similar to low-grade fibromyxoid sarcoma. So in that case, obviously you could use other stains like keratins and if you like TLE1 you could do that. And then in the end, if you have trouble, molecular pathology can help us out. Like I said earlier, these tumors, low-grade fibromyxoid sarcoma is defined by a translocation. The most common translocation is the translocation 716 which is between the genes FUS and CREB3L2. And there's also a small subset of these that have an alternate translocation which is between the FUS gene and the CREB3L1 gene. So FUS-CREB3L2 or FUS-CREB3L1 gene fusion can support the diagnosis. So you could use break apart fish for FUS. If the tumor looks like this and FUS is positive for FUS gene rearrangement, then you should be pretty good in calling it a low-grade fibromyxoid sarcoma. But do be aware that there are many other tumors in soft tissue pathology that have FUS gene rearrangements, myxoid liposarcoma and others. They usually have a different histologic appearance. So that's why you can never use, at least in my opinion, you shouldn't use molecular pathology by itself. You have to couple it with the clinical scenario and the histologic features and the immunohistochemistry findings. Put",
"med_umls_ids": "[[{'entity': 'Synovial sarcoma', 'concept_id': 'C0039101', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}], [{'entity': 'Keratin', 'concept_id': 'C0010803', 'confidence': 1.0}, {'entity': 'TLE1', 'concept_id': 'C1420752', 'confidence': 1.0}, {'entity': 'stains', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'differentiate', 'concept_id': 'C0205615', 'confidence': 0.9999998807907104}, {'entity': 'synovial sarcoma', 'concept_id': 'C0039101', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}], [{'entity': 'Low-grade fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.9999998807907104}, {'entity': 'translocation', 'concept_id': 'C0040715', 'confidence': 1.0}, {'entity': 'translocation', 'concept_id': 'C0040715', 'confidence': 1.0}, {'entity': 'FUS', 'concept_id': 'C0268696', 'confidence': 1.0}, {'entity': 'CREB3L2', 'concept_id': 'C1428221', 'confidence': 0.9999998807907104}, {'entity': 'genes', 'concept_id': 'C0017337', 'confidence': 1.0}], [{'entity': 'Break apart FISH', 'concept_id': 'C3831569', 'confidence': 0.7467014789581299}, {'entity': 'FUS', 'concept_id': 'C0268696', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}], [{'entity': 'Molecular pathology', 'concept_id': 'C0596962', 'confidence': 1.0}, {'entity': 'coupled', 'concept_id': 'C1948027', 'confidence': 1.0}, {'entity': 'clinical scenario', 'concept_id': 'C0205210', 'confidence': 0.6381967067718506}, {'entity': 'histologic features', 'concept_id': 'C1301121', 'confidence': 0.816085159778595}, {'entity': 'immunohistochemistry', 'concept_id': 'C0021044', 'confidence': 0.9999998807907104}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_909",
"caption_rating": "8"
},
{
"": "1004344",
"caption": "Clodin-1 is often expressed in perineuriomas, which can be a pitfall in diagnosis as it may resemble low-grade fibromyxoid sarcoma. Glut-1 is usually negative in perineuriomas but may be positive in rare cases of low-grade fibromyxoid sarcoma. MUC4 is a sensitive and specific marker for low-grade fibromyxoid sarcoma and should be negative in perineuriomas and DFSP.",
"image_path": "QDb68_G1HR4_image_655025bf-2bc2-4844-94e1-186bac092b47.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The one stain that was described a few years ago as being helpful here is called MUC4, M-U-C-4. MUC4 is in the setting of a fibroblastic spindle cell tumor like this, it is a very sensitive and specific marker at least as of today's date in 2018, so far it tends to be very sensitive and specific marker for low-grade fibromyxoid sarcoma and it should be negative in perineuriomas and DFSP and other entities in the differential diagnosis. Now I'm",
"corrected_text": " They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The one stain that was described a few years ago as being helpful here is called MUC4, M-U-C-4. MUC4 is in the setting of a fibroblastic spindle cell tumor like this, it is a very sensitive and specific marker at least as of today's date in 2018, so far it tends to be very sensitive and specific marker for low-grade fibromyxoid sarcoma and it should be negative in perineuriomas and DFSP and other entities in the differential diagnosis. Now I'm",
"med_umls_ids": "[[{'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}, {'entity': 'expressed', 'concept_id': 'C0017262', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'rare', 'concept_id': 'C0521114', 'confidence': 1.0}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'MUC4', 'concept_id': 'C1417496', 'confidence': 0.9999999403953552}, {'entity': 'sensitive', 'concept_id': 'C0020517', 'confidence': 1.0}, {'entity': 'marker', 'concept_id': 'C0005516', 'confidence': 0.9999999403953552}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_910",
"caption_rating": "10"
},
{
"": "1007226",
"caption": "Pyloric metaplasia is important in autoimmune gastritis.",
"image_path": "r7OA0Trj5hQ_image_dcd6971f-f861-486d-b872-e949ad5938df.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['gastric mucosa', 'body of the stomach', 'peritoneal cells', 'mucincycletine cells', 'chief cells', 'pyloric metaplasia', 'autoimmune gastritis']",
"noisy_text": " metaplasia of the gastric mucosa. Here the history is this biopsy is taken from the body of the stomach. In the body of the stomach, you have to see a lot of fried eggs. These are all the peritoneal cells in addition to mucincycletine cells and chief cells. These are the peritoneal cells. When you don't see the peritoneal cells in the gastric fundic mucosa or gastric corpus mucosa, then you have to call it as pyloric metaplasia. This is very, very important because you see it in autoimmune gastritis. Sometimes the",
"corrected_text": " metaplasia of the gastric mucosa. Here the history is this biopsy is taken from the body of the stomach. In the body of the stomach, you have to see a lot of fried eggs. These are all the peritoneal cells in addition to mucincycletine cells and chief cells. These are the peritoneal cells. When you don't see the peritoneal cells in the gastric fundic mucosa or gastric corpus mucosa, then you have to call it as pyloric metaplasia. This is very, very important because you see it in autoimmune gastritis. Sometimes the",
"med_umls_ids": "[[{'entity': 'Metaplasia', 'concept_id': 'C0025568', 'confidence': 1.0}, {'entity': 'gastric mucosa', 'concept_id': 'C0017136', 'confidence': 1.0}, {'entity': 'body', 'concept_id': 'C0227230', 'confidence': 1.0}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'peritoneal cells', 'concept_id': 'C0031153', 'confidence': 0.7749612331390381}, {'entity': 'mucincycletine cells', 'concept_id': 'C0007586', 'confidence': 0.6177586317062378}, {'entity': 'chief cells', 'concept_id': 'C1516470', 'confidence': 1.0}], [{'entity': 'Absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'peritoneal cells', 'concept_id': 'C0031153', 'confidence': 0.7749612331390381}, {'entity': 'gastric fundic mucosa', 'concept_id': 'C0017136', 'confidence': 0.8429272770881653}, {'entity': 'gastric corpus mucosa', 'concept_id': 'C0735811', 'confidence': 0.9813486337661743}, {'entity': 'pyloric metaplasia', 'concept_id': 'C4288813', 'confidence': 0.8951747417449951}], [{'entity': 'Pyloric metaplasia', 'concept_id': 'C4288813', 'confidence': 0.8951747417449951}, {'entity': 'autoimmune gastritis', 'concept_id': 'C3887639', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_911",
"caption_rating": "7"
},
{
"": "1007607",
"caption": "Lamina propria is full of cells with a distinct cell border, abundant foamy cytoplasm, and centrally placed nucleus in gastric xanthoma.",
"image_path": "r7OA0Trj5hQ_image_c7ed1339-6895-420a-bdd8-11bd0d9bacdb.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['centrally placed nucleus', 'young males', 'inflammatory bowel disease', 'lamina propria', 'distinct cell border', 'foamy cytoplasm', 'centrally placed nucleus', 'gastric xanthoma']",
"noisy_text": " It is commonly seen in young males, and they present with the signs and symptoms of inflammatory bowel disease. Interesting condition. Here, the lamina propria is full of cells with a distinct cell border, abundant foamy cytoplasm, most of the time centrally placed nucleus. Sometimes it is pushed to the periphery. The central nuclear placement is very important for a diagnosis of xanthoma. For a signet cells, it will be predominantly peripherally pushed nucleus. And when you have doubt, you do a CD68, which will be strongly positive. And so this is a gastric xanthoma. Here, it",
"corrected_text": " It is commonly seen in young males, and they present with the signs and symptoms of inflammatory bowel disease. Interesting condition. Here, the lamina propria is full of cells with a distinct cell border, abundant foamy cytoplasm, most of the time centrally placed nucleus. Sometimes it is pushed to the periphery. The central nuclear placement is very important for a diagnosis of xanthoma. For a signet ring cells, it will be predominantly peripherally pushed nucleus. And when you have doubt, you do a CD68, which will be strongly positive. And so this is a gastric xanthoma. Here, it",
"med_umls_ids": "[[{'entity': 'Xanthoma', 'concept_id': 'C0302314', 'confidence': 1.0}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}, {'entity': 'young', 'concept_id': 'C0332239', 'confidence': 1.0}, {'entity': 'males', 'concept_id': 'C0086582', 'confidence': 1.0}, {'entity': 'signs', 'concept_id': 'C0220912', 'confidence': 0.9999999403953552}, {'entity': 'symptoms', 'concept_id': 'C0683368', 'confidence': 1.0}, {'entity': 'inflammatory bowel disease', 'concept_id': 'C0021390', 'confidence': 1.0}], [{'entity': 'Lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'cell border', 'concept_id': 'C0205284', 'confidence': 0.773768424987793}, {'entity': 'foamy cytoplasm', 'concept_id': 'C0010834', 'confidence': 0.7207725048065186}, {'entity': 'centrally', 'concept_id': 'C0205099', 'confidence': 0.7070305943489075}, {'entity': 'nucleus', 'concept_id': 'C0007610', 'confidence': 1.0}, {'entity': 'gastric xanthoma', 'concept_id': 'C1282522', 'confidence': 1.0}], [{'entity': 'CD68', 'concept_id': 'C0108799', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'xanthoma', 'concept_id': 'C0302314', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_912",
"caption_rating": "9"
},
{
"": "1009428",
"caption": "Muscularization in the lamina propria is a nonspecific finding, but may indicate chemical gastritis.",
"image_path": "r7OA0Trj5hQ_image_0da56fc2-ec65-47cc-a3e5-b5888921f80d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Muscle coming in the lamina propria', 'Muscularis mucosa is hyperplastic']",
"noisy_text": " The epithelium, the glands are pushed apart each other. And this may be procedure related. This may be seen in chemical gastritis, lamina propria. It's a very nonspecific finding, not diagnostic of anything. But whenever you see, think of chemical gastritis. This is muscularization. You see in the hyperwire, muscle coming in the lamina propria. Lamina propria should be free of musculature. The muscle should be there only in the muscularis mucosa. Here in this low power, you can see the muscularis mucosa is hyperplastic. And it is sending the muscle bundle into the lamina propria. This happens in chemical gastritis in case of stomach and in",
"corrected_text": " The epithelium, the glands are pushed apart each other. And this may be procedure related. This may be seen in chemical gastritis, lamina propria. It's a very nonspecific finding, not diagnostic of anything. But whenever you see, think of chemical gastritis. This is muscularization. You see in the hyperplasia, muscle coming in the lamina propria. Lamina propria should be free of musculature. The muscle should be there only in the muscularis mucosa. Here in this low power, you can see the muscularis mucosa is hyperplastic. And it is sending the muscle bundle into the lamina propria. This happens in chemical gastritis in case of stomach and in",
"med_umls_ids": "[[{'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'procedure-related', 'concept_id': 'C2924519', 'confidence': 1.0}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}], [{'entity': 'Muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'nonspecific', 'concept_id': 'C0750540', 'confidence': 1.0}, {'entity': 'finding', 'concept_id': 'C0037088', 'confidence': 1.0}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}], [{'entity': 'Muscle', 'concept_id': 'C0026845', 'confidence': 1.0}, {'entity': 'muscularis mucosa', 'concept_id': 'C0225357', 'confidence': 0.9999998807907104}, {'entity': 'hyperplasia', 'concept_id': 'C0020507', 'confidence': 1.0}, {'entity': 'muscle bundles', 'concept_id': 'C0504095', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}], [{'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_913",
"caption_rating": "9"
},
{
"": "1005838",
"caption": "Intraluminal proliferation of epithelium is an important criteria for high-grade dysplasia, which is characterized by loss of cellular polarity, nuclei reaching the surface, prominent nuclei, and cribriform and micropapillary patterns. The concept of dysplasia includes low-grade dysplasia.",
"image_path": "r7OA0Trj5hQ_image_2ce326b1-f0b1-4bfc-82aa-4443f4bd44cf.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Nuclei reaching the surface', 'Nuclei reaching the surface', 'Nuclei reaching the surface']",
"noisy_text": " and connecting the other side of the lumen. So the intra-glandular proliferation of the epithelium is very, very important criteria, which we call it as cribriformic for high-grade dysplasia. So this is a picture of high-grade dysplasia. And the criteria are loss of polarity, nuclei reaching the surface. Here you can see nuclei reaching the surface. Prominent nuclei, if you see carefully for 10 seconds, you can start seeing the nuclei and cribriformic and micropapillary. This concept of dysplasia, low-grade dysplasia and high-grade",
"corrected_text": " and connecting the other side of the lumen. So the intra-glandular proliferation of the epithelium is very, very important criteria, which we call it as cribriform for high-grade dysplasia. So this is a picture of high-grade dysplasia. And the criteria are loss of polarity, nuclei reaching the surface. Here you can see nuclei reaching the surface. Prominent nuclei, if you see carefully for 10 seconds, you can start seeing the nuclei and cribriform and micropapillary. This concept of dysplasia, low-grade dysplasia and high-grade",
"med_umls_ids": "[[{'entity': 'Intraluminal proliferation', 'concept_id': 'C0334094', 'confidence': 0.7116578221321106}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'criteria', 'concept_id': 'C0243161', 'confidence': 0.9999998807907104}, {'entity': 'high-grade dysplasia', 'concept_id': 'C1333110', 'confidence': 0.8831341862678528}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'loss', 'concept_id': 'C1517945', 'confidence': 1.0}, {'entity': 'cellular polarity', 'concept_id': 'C0085304', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'cribriform', 'concept_id': 'C1621425', 'confidence': 0.9999999403953552}, {'entity': 'micropapillary', 'concept_id': 'C1290608', 'confidence': 0.891559898853302}, {'entity': 'concept', 'concept_id': 'C0178566', 'confidence': 1.0}, {'entity': 'dysplasia', 'concept_id': 'C0334044', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'dysplasia', 'concept_id': 'C0334044', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_914",
"caption_rating": "9"
},
{
"": "1006270",
"caption": "Focal area of calcification can be seen in the tumor.",
"image_path": "PJX3uZ7fRn4_image_6e06942c-9cdd-4403-a87b-fb8b5258284b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gynecologic', 'Soft tissue', 'Hematopathology']",
"roi_text": "['vascular channels', 'chorionic villi', 'calcification', 'vascular channels', 'chorionic villi', 'calcification']",
"noisy_text": " This is a section from placenta which shows a large irregular area with proliferation of thin walled vascular channels of variable size towards the fetal surface of placenta. Smaller chorionic villi can be seen towards the maternal site. Higher magnification of the same showing large vascular channels in the chorion filled with blood. Still higher magnification showing intercommunicating slit-like vascular spaces in the mass. Focal area of calcification can be seen in the tumor. Still another area",
"corrected_text": " This is a section from placenta which shows a large irregular area with proliferation of thin walled vascular channels of variable size towards the fetal surface of placenta. smaller chorionic villi are not incorrect can be seen towards the maternal site. Higher magnification of the same showing large vascular channels in the chorion filled with blood. Still higher magnification showing intercommunicating slit-like vascular spaces in the mass. Focal area of calcification can be seen in the tumor. Still another area",
"med_umls_ids": "[[{'entity': 'Proliferation', 'concept_id': 'C0334094', 'confidence': 1.0}, {'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}, {'entity': 'variable size', 'concept_id': 'C1866144', 'confidence': 0.8559831976890564}, {'entity': 'fetal', 'concept_id': 'C0015965', 'confidence': 1.0}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'placenta', 'concept_id': 'C0032043', 'confidence': 1.0}], [{'entity': 'chorionic villi', 'concept_id': 'C0008508', 'confidence': 1.0}, {'entity': 'maternal site', 'concept_id': 'C0026591', 'confidence': 0.7640593647956848}], [{'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}, {'entity': 'chorion', 'concept_id': 'C0008503', 'confidence': 0.9999998807907104}, {'entity': 'blood', 'concept_id': 'C0005767', 'confidence': 1.0}], [{'entity': 'Intercommunicating', 'concept_id': 'C0205196', 'confidence': 0.8271207213401794}, {'entity': 'vascular spaces', 'concept_id': 'C0225983', 'confidence': 0.819495439529419}, {'entity': 'mass', 'concept_id': 'C0577559', 'confidence': 1.0}], [{'entity': 'Focal area', 'concept_id': 'C0205234', 'confidence': 0.7634891271591187}, {'entity': 'calcification', 'concept_id': 'C0006660', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_915",
"caption_rating": "7"
},
{
"": "1008269",
"caption": "The glands seen in the image are pyloric gland metaplasia, which can be seen in colitis, end-associated injury, and mycophenol-associated injury.",
"image_path": "sDFjOtMAYrk_image_45cc0a3c-bc97-4a1d-a4a4-bd980ddb1f6f.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['pyloric gland metaplasia', 'solid organ transplant recipient', 'eosinophils']",
"noisy_text": " Yeah, these cells, these glands right here. What is it? Yeah, exactly. It's a pyloric glomeruloplasia. So pyloric glomeruloplasia should be Crohn's. No, you can see pyloric glomeruloplasia in your sort of a colitis and end-associated injury and also in microphenol-associated injury, as this case is. And the tip of the patient is a solid organ transplant recipient. with microphenol-associated injury have many more in the way of eosinophils, a lot more in the way of eosinophils than GVHD patients do. So that's really, really helpful. Is there",
"corrected_text": " Yeah, these cells, these glands right here. What is it? Yeah, exactly. It's a pyloric gland metaplasia. So pyloric gland metaplasia should be Crohn's. No, you can see pyloric gland metaplasia in your sort of a colitis and end-associated injury and also in mycophenol-associated injury, as this case is. And the tip of the patient is a solid organ transplant recipient. with mycophenol-associated injury have many more in the way of eosinophils, a lot more in the way of eosinophils than GVHD patients do. So that's really, really helpful. Is there",
"med_umls_ids": "[[{'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'image', 'concept_id': 'C1696103', 'confidence': 1.0}, {'entity': 'pyloric gland metaplasia', 'concept_id': 'C4288813', 'confidence': 1.0}, {'entity': 'colitis', 'concept_id': 'C0009319', 'confidence': 1.0}, {'entity': 'end-associated injury', 'concept_id': 'C0552509', 'confidence': 0.6716579794883728}, {'entity': 'mycophenol-associated injury', 'concept_id': 'C0552509', 'confidence': 0.6023857593536377}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'solid organ transplant', 'concept_id': 'C0730400', 'confidence': 1.0}, {'entity': 'recipient', 'concept_id': 'C1709854', 'confidence': 1.0}, {'entity': 'mycophenol-associated injury', 'concept_id': 'C0552509', 'confidence': 0.6023857593536377}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'GVHD', 'concept_id': 'C0018133', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_916",
"caption_rating": "8"
},
{
"": "1009429",
"caption": "Muscle should only be present in the muscularis mucosa, but hyperplasia can cause muscle bundles to extend into the lamina propria.",
"image_path": "r7OA0Trj5hQ_image_0da56fc2-ec65-47cc-a3e5-b5888921f80d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Muscle coming in the lamina propria', 'Muscularis mucosa is hyperplastic']",
"noisy_text": " The epithelium, the glands are pushed apart each other. And this may be procedure related. This may be seen in chemical gastritis, lamina propria. It's a very nonspecific finding, not diagnostic of anything. But whenever you see, think of chemical gastritis. This is muscularization. You see in the hyperwire, muscle coming in the lamina propria. Lamina propria should be free of musculature. The muscle should be there only in the muscularis mucosa. Here in this low power, you can see the muscularis mucosa is hyperplastic. And it is sending the muscle bundle into the lamina propria. This happens in chemical gastritis in case of stomach and in",
"corrected_text": " The epithelium, the glands are pushed apart each other. And this may be procedure related. This may be seen in chemical gastritis, lamina propria. It's a very nonspecific finding, not diagnostic of anything. But whenever you see, think of chemical gastritis. This is muscularization. You see in the hyperplasia, muscle coming in the lamina propria. Lamina propria should be free of musculature. The muscle should be there only in the muscularis mucosa. Here in this low power, you can see the muscularis mucosa is hyperplastic. And it is sending the muscle bundle into the lamina propria. This happens in chemical gastritis in case of stomach and in",
"med_umls_ids": "[[{'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'procedure-related', 'concept_id': 'C2924519', 'confidence': 1.0}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}], [{'entity': 'Muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'nonspecific', 'concept_id': 'C0750540', 'confidence': 1.0}, {'entity': 'finding', 'concept_id': 'C0037088', 'confidence': 1.0}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}], [{'entity': 'Muscle', 'concept_id': 'C0026845', 'confidence': 1.0}, {'entity': 'muscularis mucosa', 'concept_id': 'C0225357', 'confidence': 0.9999998807907104}, {'entity': 'hyperplasia', 'concept_id': 'C0020507', 'confidence': 1.0}, {'entity': 'muscle bundles', 'concept_id': 'C0504095', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}], [{'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_917",
"caption_rating": "9"
},
{
"": "1007291",
"caption": "The presence of one or two concerning glands at the edge of a case is not enough to diagnose high grade prostatic intraepithelial neoplasia (PIN) or prostate cancer.",
"image_path": "iklRyY1nBIE_image_de2ff8a9-2c40-4501-afd1-3d30010ed83f.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['glands at the edge', 'glands at the edge']",
"noisy_text": " and then we're going to come to the edge here. So assuming all I had was just one or two glands like this at the edge, let's say we had those two glands over here, right at the edge over here, and nothing else in the entire case, nothing else at all. Even though they look very concerning, assuming both of them were right here, even though they look very concerning, that would not be enough to pull the trigger. So this would be a good example of a typical small acinar proliferation or ASAP, because the glands at the edge, it's possible there could be a high grade pin focus here without patching of these atypical looking glands. What you call ASAP should be something that is really, really suspicious. So we'll stop there for case one, and then we'll move on to",
"corrected_text": " and then we're going to come to the edge here. So assuming all I had was just one or two glands like this at the edge, let's say we had those two glands over here, right at the edge over here, and nothing else in the entire case, nothing else at all. Even though they look very concerning, assuming both of them were right here, even though they look very concerning, that would not be enough to pull the trigger. So this would be a good example of a typical small acinar proliferation or ASAP, because the glands at the edge, it's possible there could be a high grade pin focus here without patching of these atypical looking glands. What you call ASAP should be something that is really, really suspicious. So we'stop there for case one, and then we'll move on to",
"med_umls_ids": "[[{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'edge', 'concept_id': 'C0205154', 'confidence': 1.0}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'prostatic intraepithelial neoplasia', 'concept_id': 'C0282612', 'confidence': 1.0}, {'entity': 'PIN', 'concept_id': 'C0175718', 'confidence': 1.0}, {'entity': 'prostate cancer', 'concept_id': 'C0376358', 'confidence': 1.0}], [{'entity': 'ASAP', 'concept_id': 'C0683504', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_918",
"caption_rating": "9"
},
{
"": "1004327",
"caption": "Some glands are negative for basal cell markers while others are patchy positive, but all glands have similar cytologic features in the nucleus and cytoplasm, indicating partial atrophy.",
"image_path": "iklRyY1nBIE_image_663893da-49b1-47c7-b44b-b0adb80ffaf4.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['negative for basal cell markers', 'patchy positive for basal cell markers', 'similar cytologic features', 'partial atrophy', 'partial atrophic hyperplasia', 'inflammation', 'well circumscribed cluster of glands', 'negative for basal cell markers', 'patchy positive for basal cell markers', 'similar cytologic features', 'partial atrophy', 'partial atrophic hyperplasia', 'inflammation', 'well circumscribed cluster of glands']",
"noisy_text": " But some cases are tricky like this one, where some of the glands are completely negative for basal cell markers, while others are patchy positive for basal cell markers. But once you recognize on the H and E that both, you know, all these glands have similar cytologic features, both in the nucleus and the cytoplasm, that should make your life very easy. So this was a very good case of partial atrophy. I have some other cases I'll share with you very quickly. Similar scenario, but with a few differences. So this is one case. This is another case. There's partial atrophic hyperplasia over here with some inflammation. But if you come to this area over here, again, you see a fairly well circumscribed cluster of glands. And if",
"corrected_text": " But some cases are tricky like this one, where some of the glands are completely negative for basal cell markers, while others are patchy positive for basal cell markers. But once you recognize on the H and E that both, you know, all these glands have similar cytologic features, both in the nucleus and the cytoplasm, that should make your life very easy. So this was a very good case of partial atrophy. I have some other cases I'share with you very quickly. Similar scenario, but with a few differences. So this is one case. This is another case. There's partial atrophic hyperplasia over here with some inflammation. But if you come to this area over here, again, you see a fairly well circumscribed cluster of glands. And if",
"med_umls_ids": "[[{'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'basal cell', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'markers', 'concept_id': 'C0181734', 'confidence': 0.890313982963562}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'cytologic features', 'concept_id': 'C0205471', 'confidence': 0.7179956436157227}, {'entity': 'nucleus', 'concept_id': 'C0007610', 'confidence': 1.0}, {'entity': 'cytoplasm', 'concept_id': 'C0010834', 'confidence': 1.0}, {'entity': 'partial', 'concept_id': 'C0728938', 'confidence': 1.0}, {'entity': 'atrophy', 'concept_id': 'C0333641', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_919",
"caption_rating": "8"
},
{
"": "1008647",
"caption": "Presence of several melanocytes, some forming nests, some as confluence solitary units, along the base of the matrix epithelium in the matrix layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern.",
"image_path": "8S4LeiO6Bbk_image_59b75d51-8011-42e1-9838-b22e2144b31f.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Presence of several melanocytes', 'too many melanocytes', 'Presence of several melanocytes', 'forming nests', 'confluence solitary units', 'matrix epithelium', 'basal layer of the matrix', 'upper portions of the matrix', 'pagetoid pattern', 'too many melanocytes', 'basal layer of the matrix', 'upper portions of the matrix']",
"noisy_text": " examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matricle epithelium in the matricle layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that being said, we'll go ahead and move on to slide number two, which was a melanin A or Mk1 immunohistochemical stain of this same piece of tissue. Underneath this bubble here we have our control. This is",
"corrected_text": " examination hopefully what was readily apparent to you was the presence of several melanocytes, some forming nests, some as confluence solitary units, not only along the base of the matrix epithelium in the matrix layer, in the basal layer of the matrix rather, but also extending into the upper portions of the matrix in a pagetoid pattern. And there are way too many melanocytes here in the matrix and these findings are highly suspicious for melanoma in situ. So with that being said, we'll go ahead and move on to slide number two, which was a melanin A or Mk1 immunohistochemical stain of this same piece of tissue. Underneath this bubble here we have our control. This is",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'nests', 'concept_id': 'C0035253', 'confidence': 0.7275967001914978}, {'entity': 'confluence', 'concept_id': 'C0226863', 'confidence': 0.857487678527832}, {'entity': 'solitary units', 'concept_id': 'C0205171', 'confidence': 0.7227572798728943}, {'entity': 'base', 'concept_id': 'C0002055', 'confidence': 1.0}, {'entity': 'matrix epithelium', 'concept_id': 'C0014609', 'confidence': 0.7584323883056641}, {'entity': 'matrix layer', 'concept_id': 'C0331858', 'confidence': 0.71736741065979}, {'entity': 'basal layer', 'concept_id': 'C0221925', 'confidence': 1.0}, {'entity': 'matrix', 'concept_id': 'C0331858', 'confidence': 1.0}, {'entity': 'upper portions', 'concept_id': 'C0449719', 'confidence': 0.6251541972160339}, {'entity': 'matrix', 'concept_id': 'C0331858', 'confidence': 1.0}, {'entity': 'pagetoid', 'concept_id': 'C1518847', 'confidence': 0.8801172375679016}, {'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}], [{'entity': 'melanocytes', 'concept_id': 'C0025201', 'confidence': 1.0}, {'entity': 'matrix', 'concept_id': 'C0331858', 'confidence': 1.0}, {'entity': 'suspicious', 'concept_id': 'C0750493', 'confidence': 1.0}, {'entity': 'melanoma', 'concept_id': 'C0025202', 'confidence': 1.0}, {'entity': 'in situ', 'concept_id': 'C0444498', 'confidence': 0.9999999403953552}]]",
"magnification": "1.0",
"height": "758.0",
"width": "1920.0",
"id": "test_920",
"caption_rating": "9"
},
{
"": "1008755",
"caption": "Presence of a deep nodular aggregate of blue cells, which may indicate lymphoma.",
"image_path": "udoW6VSqsm4_image_3e779bfb-2d52-42f2-b30c-dd40ea7f16c3.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['Deep nodular aggregate of blue cells']",
"noisy_text": " You're not going to be asked to be a lymphoma pathologist on the board, but it's kind of important to just know, because if you see these patients in practice, you don't want them to get up in the hands of an oncologist. The object will get up from here, like we normally do. Okay, who wants to give this one a go? We have a pretty deep nodular aggregate of blue cells here, pretty well debarcated. You can see it's a low power. And other than that, I guess in this power you can see that some of them, I thought the differentiation was sebaceous. They're definitely a minority of the neoplasm, but definitely there. Is it possible",
"corrected_text": " You're not going to be asked to be a lymphoma pathologist on the board, but it's kind of important to just know, because if you see these patients in practice, you don't want them to get up in the hands of an oncologist. The object will get up from here, like we normally do. Okay, who wants to give this one a go? We have a pretty deep nodular aggregate of blue cells here, pretty well circumscribed. You can see it's a low power. And other than that, I guess in this power you can see that some of them, I thought the differentiation was sebaceous. They're definitely a minority of the neoplasm, but definitely there. Is it possible",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'deep nodular', 'concept_id': 'C0205297', 'confidence': 0.7114682197570801}, {'entity': 'aggregate', 'concept_id': 'C0205418', 'confidence': 1.0}, {'entity': 'blue cells', 'concept_id': 'C0010520', 'confidence': 0.8241713047027588}, {'entity': 'lymphoma', 'concept_id': 'C0024299', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_921",
"caption_rating": "9"
},
{
"": "1004986",
"caption": "Surgical resection of solitary metastases from the lung may prolong the disease course.",
"image_path": "QDb68_G1HR4_image_b3c3132f-0ea6-4040-a517-87c50dadd4c7.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " diagnosis when a metastasis finally shows up. So unfortunately, that's a frustrating thing I think for both the treating physicians and the patients to know that basically you're never totally in the clear these things can recur or metastasize very, very long after diagnosis. When they metastasize, they often go to the lung or the pleura and there probably is some benefit at least in the opinion of some of the people that I know who treat these sarcomas in removing solitary metastases from the lung if they're surgically amenable to surgical resection that you can remove the metastasis and then the patient may go quite a few more years before having another metastasis. So you can really kind of prolong the disease course by removing metastasis. Obviously if you're a patient watching this that has this tumor, please make sure you see an expert",
"corrected_text": " diagnosis when a metastasis finally shows up. So unfortunately, that's a frustrating thing I think for both the treating physicians and the patients to know that basically you're never totally in the clear these things can recur or metastasize very, very long after diagnosis. When they metastasize, they often go to the lung or the pleura and there probably is some benefit at least in the opinion of some of the people that I know who treat these sarcomas in removing solitary metastases from the lung if they're surgically amenable to surgical resection that you can remove the metastasis and then the patient may go quite a few more years before having another metastasis. So you can really kind of prolong the disease course by removing metastasis. Obviously if you're a patient watching this that has this tumor, please make sure you see an expert",
"med_umls_ids": "[[{'entity': 'Metastasis', 'concept_id': 'C0027627', 'confidence': 1.0}, {'entity': 'metastasize', 'concept_id': 'C0027627', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'lung', 'concept_id': 'C0024109', 'confidence': 1.0}, {'entity': 'pleura', 'concept_id': 'C0032225', 'confidence': 1.0}], [{'entity': 'Surgical resection', 'concept_id': 'C0015252', 'confidence': 1.0}, {'entity': 'solitary metastases', 'concept_id': 'C0027627', 'confidence': 0.7712292075157166}, {'entity': 'lung', 'concept_id': 'C0024109', 'confidence': 1.0}, {'entity': 'disease course', 'concept_id': 'C0242656', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_922",
"caption_rating": "8"
},
{
"": "1009013",
"caption": "The low-grade fibromyxoid sarcoma or Evans tumor usually does not have pleomorphism, which is distinctly different from myxofibrosarcoma.",
"image_path": "QDb68_G1HR4_image_2a177f89-5009-48b9-8374-922dce4c7ba5.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " kind of rounded or triangle shaped but even still we really just don't see anything that looks like marked atypia or pleomorphism which is distinctly different from myxofibrosarcoma which again I have another video about that I'll put a link in the video description and up in the upper right hand corner. Myxofibrosarcomas are by definition pleomorphic sarcomas, they're aneuploid, they do not have translocations, they have random gains and losses and thus they have pleomorphism. So even in the grade 1, the low grade form of myxofibrosarcoma, you have to have pleomorphism, that's a different tumor than this low grade fibromyxoid sarcoma or Evans tumor which usually does not have pleomorphism, okay? So the myxoid areas here look a little different than the fibrous areas. So I'm",
"corrected_text": " kind of rounded or triangle shaped but even still we really just don't see anything that looks like marked atypia or pleomorphism which is distinctly different from myxofibrosarcoma which again I have another video about that I'll put a link in the video description and up in the upper right hand corner. myxofibrosarcoma are by definition pleomorphic sarcomas, they're aneuploid, they do not have translocations, they have random gains and losses and thus they have pleomorphism. So even in the grade 1, the low grade form of myxofibrosarcoma, you have to have pleomorphism, that's a different tumor than this low grade fibromyxoid sarcoma or Evans tumor which usually does not have pleomorphism, okay? So the myxoid areas here look a little different than the fibrous areas. So I'm",
"med_umls_ids": "[[{'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'Evans tumor', 'concept_id': 'C2697858', 'confidence': 0.6359843015670776}, {'entity': 'pleomorphism', 'concept_id': 'C0032219', 'confidence': 1.0}, {'entity': 'myxofibrosarcoma', 'concept_id': 'C3714524', 'confidence': 1.0}], [{'entity': 'Myxofibrosarcoma', 'concept_id': 'C3714524', 'confidence': 1.0}, {'entity': 'pleomorphic sarcoma', 'concept_id': 'C1261358', 'confidence': 0.9260651469230652}, {'entity': 'aneuploidy', 'concept_id': 'C0002938', 'confidence': 1.0}, {'entity': 'random', 'concept_id': 'C0034656', 'confidence': 1.0}, {'entity': 'gains', 'concept_id': 'C1517378', 'confidence': 0.7974324226379395}, {'entity': 'losses', 'concept_id': 'C0018840', 'confidence': 0.786555290222168}], [{'entity': 'myxoid areas', 'concept_id': 'C0205295', 'confidence': 0.8464413285255432}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'fibrous areas', 'concept_id': 'C0439709', 'confidence': 0.783623218536377}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_923",
"caption_rating": "9"
},
{
"": "1009070",
"caption": "The tumor has both an epithelial and spindle cell component, with concerning features in the epithelial component.",
"image_path": "iklRyY1nBIE_image_c49b67e3-332c-4010-98ee-fa3925d7a0cc.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['Wild tumor with bad nuclei', 'Mitotic activity', 'Epithelial and spindle cell component', 'Pain cocktail stain']",
"noisy_text": " We need to exclude these two. And I'll just let you all take a look at this and try and figure out what's going on. So this looks like another wild tumor of bad nuclei. If you look carefully, you can see some mitotic activity there. This looks like it has both an epithelial and a stromal component to it, or at least an epithelial and a spindle cell component to it. The epithelial component looks concerning. And if I show you the corresponding stain, that will give it away. This will give the diagnosis away. So this is the pain cocktail. And as you can see, it's negative in the epithelial component for basal cells.",
"corrected_text": " We need to exclude these two. And I'll just let you all take a look at this and try and figure out what's going on. So this looks like another wild tumor of bad nuclei. If you look carefully, you can see some mitotic activity there. This looks like it has both an epithelial and spindle cell component to it, or at least an epithelial and a spindle cell component to it. The epithelial component looks concerning. And if I show you the corresponding stain, that will give it away. This will give the diagnosis away. So this is the pain cocktail. And as you can see, it's negative in the epithelial component for basal cells.",
"med_umls_ids": "[[{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'epithelial', 'concept_id': 'C0221908', 'confidence': 1.0}, {'entity': 'spindle cell', 'concept_id': 'C0682540', 'confidence': 0.9999999403953552}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'epithelial component', 'concept_id': 'C1707933', 'confidence': 0.8783122897148132}], [{'entity': 'Mitotic activity', 'concept_id': 'C1334779', 'confidence': 1.0}], [{'entity': 'pain cocktail', 'concept_id': 'C0678420', 'confidence': 0.9142165184020996}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'epithelial component', 'concept_id': 'C1707933', 'confidence': 0.8783122897148132}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_924",
"caption_rating": "9"
},
{
"": "1008438",
"caption": "Myxoid liposarcoma can metastasize to the lungs.",
"image_path": "pBR26SS0FX8_image_decfa00c-795e-44d0-9da3-0464679a982a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Hematopathology', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " and not other parts of pathology where you have to calculate percent of key 67 staining and stuff. So anyway, I don't know if that's a good answer, but it's an honest one. Yeah, so the question brought up is that post treatment, once these tumors have been radiated, they usually, the vast majority of them just completely get wiped out. And all that's left is sclerotic collagen, a little bit of the vascular branchy stuff and mature adipocytes with occasional little tiny lipoblasts, maybe a few pockets of myxoid change. And if there was a round cell component, you'll never know because it usually gets wiped out and blasted by the radiation. So I agree, that's the problem. The trade-off is that doing the needle ahead of time to get the diagnosis on a needle biopsy allows you to make a diagnosis and pre-treat the tumor. The trade-off though, is that on the excision specimen, you'll really never probably know what the original morphology was like. And I feel like this is one of the trade-offs we've made in modern medicine, where there are benefits of having a needle biopsy before excision, a lot of benefits and probably more benefits than risks, but there are some downsides. And that's one of them is pre-treatment, wipes out the original morphology. But again, it's the main difference is the prognosis. The long-term prognosis is worse, unfortunately, for patients that have high-grade round cell morphology. And even though the low-grade myxoid liposarcoma, in the past, there was a thought that like, 90% of the patients were gonna be okay and 10% would get METs. But I think with longer follow-up, we started to see that a significantly larger number actually even of people with low-grade conventional myxoid liposarcoma will get metastases. I think the WHO says, I think their current quote is between 30 and it's more than 30%, I think. And different studies show different things so that even sometimes it's longer and farther out. Oh yeah, I forgot to mention, the other weird thing that you should know about myxoid liposarcoma, like all sarcomas, it will metastasize the lungs oftentimes. But it",
"corrected_text": " and not other parts of pathology where you have to calculate percent of key 67 staining and stuff. So anyway, I don't know if that's a good answer, but it's an honest one. Yeah, so the question brought up is that post treatment, once these tumors have been radiated, they usually, the vast majority of them just completely get wiped out. And all that's left is sclerotic collagen, a little bit of the vascular branching and mature adipocytes with occasional little tiny lipoblasts, maybe a few pockets of myxoid change. And if there was a round cell component, you'll never know because it usually gets wiped out and blasted by the radiation. So I agree, that's the problem. The trade-off is that doing the needle ahead of time to get the diagnosis on a needle biopsy allows you to make a diagnosis and pre-treat the tumor. The trade-off though, is that on the excision specimen, you'll really never probably know what the original morphology was like. And I feel like this is one of the trade-offs we've made in modern medicine, where there are benefits of having a needle biopsy before excision, a lot of benefits and probably more benefits than risks, but there are some downsides. And that's one of them is pre-treatment, wipes out the original morphology. But again, it's the main difference is the prognosis. The long-term prognosis is worse, unfortunately, for patients that have high-grade round cell morphology. And even though the low-grade myxoid liposarcoma, in the past, there was a thought that like, 90% of the patients were gonna be okay and 10% would get METs. But I think with longer follow-up, we started to see that a significantly larger number actually even of people with low-grade conventional myxoid liposarcoma will get metastases. I think the WHO says, I think their current quote is between 30 and it's more than 30%, I think. And different studies show different things so that even sometimes it's longer and farther out. Oh yeah, I forgot to mention, the other weird thing that you should know about myxoid liposarcoma, like all sarcomas, it will metastasize the lungs oftentimes. But it",
"med_umls_ids": "[[{'entity': 'Radiation treatment', 'concept_id': 'C1522449', 'confidence': 0.9999999403953552}, {'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'sclerotic', 'concept_id': 'C0036429', 'confidence': 0.9999999403953552}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'vascular branching', 'concept_id': 'C0005847', 'confidence': 0.7225151658058167}, {'entity': 'mature', 'concept_id': 'C0205286', 'confidence': 1.0}, {'entity': 'adipocytes', 'concept_id': 'C0206131', 'confidence': 1.0}, {'entity': 'lipoblasts', 'concept_id': 'C0225323', 'confidence': 0.8551441431045532}, {'entity': 'myxoid change', 'concept_id': 'C0205295', 'confidence': 0.815497636795044}], [{'entity': 'Needle biopsy', 'concept_id': 'C0005560', 'confidence': 1.0}, {'entity': 'excision', 'concept_id': 'C0015252', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'pre-treatment', 'concept_id': 'C0419819', 'confidence': 0.7933163046836853}, {'entity': 'original', 'concept_id': 'C0205313', 'confidence': 1.0}, {'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}], [{'entity': 'Prognosis', 'concept_id': 'C0033325', 'confidence': 1.0}, {'entity': 'patients', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'high-grade round cell', 'concept_id': 'C1512433', 'confidence': 0.7649602890014648}, {'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}], [{'entity': 'Low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'myxoid liposarcoma', 'concept_id': 'C0206634', 'confidence': 1.0}, {'entity': 'metastasize', 'concept_id': 'C0027627', 'confidence': 1.0}], [{'entity': 'Myxoid liposarcoma', 'concept_id': 'C0206634', 'confidence': 1.0}, {'entity': 'metastasize', 'concept_id': 'C0027627', 'confidence': 1.0}, {'entity': 'lungs', 'concept_id': 'C0024109', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_925",
"caption_rating": "7"
},
{
"": "1006484",
"caption": "The architecture of the glands is distorted and abnormal, indicating chronicity. No specific features are present in chronic inflammatory colonic pathology.",
"image_path": "sDFjOtMAYrk_image_ca673012-5fb7-4473-b88a-43e4407f4f1c.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['Distorted architecture of the glands.', 'Distorted architecture of the glands.']",
"noisy_text": " architecture. The glands start to look like anything they want to look like. Rabbits, monkeys, the face of Jesus, whatever, except for test tubes on a rack. And the other thing is, sometimes you'll see them instead of growing down, they'll grow sideways. So, that's very apparent, very abnormal. So, I would say this is great evidence of chronicity, good architectural distortion. What other features besides architecture can you see in cases where there's some chronicity, albeit nonspecific findings? I mean, nothing is specific in chronic inflammatory colonic pathology, but what other features would you expect to see in patients with inflammatory bowel disease? I don't remember, I think this is obviously from the right colon. So, if we see it here, it doesn't matter. But in cases from the left colon, what's a good finding that indicates chronicity? Yes,",
"corrected_text": " architecture. The glands start to look like anything they want to look like. Rabbits, monkeys, the face of Jesus, whatever, except for test tubes on a rack. And the other thing is, sometimes you'll see them instead of growing down, they'll grow sideways. So, that's very apparent, very abnormal. So, I would say this is great evidence of chronicity, good architectural distortion. What other features besides architecture can you see in cases where there's some chronicity, albeit nonspecific findings? I mean, nothing is specific in chronic inflammatory colonic pathology, but what other features would you expect to see in patients with inflammatory bowel disease? I don't remember, I think this is obviously from the right colon. So, if we see it here, it doesn't matter. But in cases from the left colon, what's a good finding that indicates chronicity? Yes,",
"med_umls_ids": "[[{'entity': 'architecture', 'concept_id': 'C0003737', 'confidence': 1.0}, {'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'distorted', 'concept_id': 'C0700135', 'confidence': 1.0}, {'entity': 'abnormal', 'concept_id': 'C0205161', 'confidence': 1.0}, {'entity': 'chronicity', 'concept_id': 'C0547045', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'chronic inflammatory colonic', 'concept_id': 'C0021376', 'confidence': 0.8024523258209229}, {'entity': 'pathology', 'concept_id': 'C0030664', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_926",
"caption_rating": "9"
},
{
"": "1008373",
"caption": "This was an example of a biopsy from a patient with clinically documented pityriasis lichenoides chronica.",
"image_path": "8S4LeiO6Bbk_image_c658e2d5-2f96-4420-8deb-ba2464e369ea.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Infiltrate within the dermis composed entirely of lymphocytes.', 'Few extravasated erythrocytes in some areas.', 'Few extravasated erythrocytes in some areas.', 'Infiltrate within the dermis composed entirely of lymphocytes.', 'Few extravasated erythrocytes in some areas.', 'Fragmented biopsy specimen with bluish stain.']",
"noisy_text": " and if we look at the infiltrate within the dermis, we can see that it's composed entirely of lymphocytes. In some areas, there were a few extravasated erythrocytes, a few of which were carried up into the overlying epidermis. This constellation of findings is most suggestive of pittoriasis liganoides. Clinically, this patient had PLC, or pittoriasis liganoides chronica. I tend to view pittoriasis liganoides as running along a spectrum. A lot of times, we'll refer to the entire spectrum as Leuka Habermann disease, with pittoriasis liganoides chronica being on the one end of the spectrum, and pleva being on the other end of the spectrum, PLC being characterized by more scaly macules or scaly papules, and pleva being characterized by more crusted and eroded papulonecrotic type lesions. But the histology of the two conditions is actually quite similar. It's a matter of degree. With pleva, you're more likely the acute form of the condition to see more spongiosis, ballooning, necrosis, a denser infiltrate, more necrotics along the DEJ, pericaratosis containing neutrophils. With PLC, similar findings, just a little more blunt. The inflammatory infiltrate may be present around the superficial plexus only. One usually can see some pericaratosis, but there aren't as many necrotic keratinocytes along the DEJ, and a lot of times, the alterations within the epidermis are more subtle. But this was an example of biopsy from a patient with clinically documented pittoriasis like in wades clonica. Moving on to slide number 10. This was, I thought, a really cool case. This was a fragmented biopsy specimen, and you can see that the stain is quite bluish. I can't",
"corrected_text": " and if we look at the infiltrate within the dermis, we can see that it's composed entirely of lymphocytes. In some areas, there were a few extravasated erythrocytes, a few of which were carried up into the overlying epidermis. This constellation of findings is most suggestive of pityriasis lichenoides. Clinically, this patient had PLC, or pityriasis lichenoides chronica. I tend to view pityriasis lichenoides as running along a spectrum. A lot of times, we'refer to the entire spectrum as Leuka Habermann disease, with pityriasis lichenoides chronica being on the one end of the spectrum, and pleva being on the other end of the spectrum, PLC being characterized by more scaly macules or scaly papules, and pleva being characterized by more crusted and eroded papulonecrotic type lesions. But the histology of the two conditions is actually quite similar. It's a matter of degree. With pleva, you're more likely the acute form of the condition to see more spongiosis, ballooning, necrosis, a denser infiltrate, more necrotic along the DEJ, parakeratosis containing neutrophils. With PLC, similar findings, just a little more blunt. The inflammatory infiltrate may be present around the superficial plexus only. One usually can see some parakeratosis, but there aren't as many necrotic keratinocytes along the DEJ, and a lot of times, the alterations within the epidermis are more subtle. But this was an example of biopsy from a patient with clinically documented pittoriasis like in chronica. Moving on to slide number 10. This was, I thought, a really cool case. This was a fragmented biopsy specimen, and you can see that the stain is quite bluish. I can't",
"med_umls_ids": "[[{'entity': 'dermal infiltrate', 'concept_id': 'C0332448', 'confidence': 0.8524853587150574}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'extravasated', 'concept_id': 'C0015376', 'confidence': 0.868863582611084}, {'entity': 'erythrocytes', 'concept_id': 'C0014772', 'confidence': 1.0}, {'entity': 'areas', 'concept_id': 'C0205146', 'confidence': 1.0}, {'entity': 'pityriasis', 'concept_id': 'C0032024', 'confidence': 0.9999998807907104}, {'entity': 'lichenoides', 'concept_id': 'C0443248', 'confidence': 0.8475416302680969}], [{'entity': 'Pityriasis lichenoides', 'concept_id': 'C0162853', 'confidence': 1.0}, {'entity': 'running', 'concept_id': 'C0035953', 'confidence': 1.0}, {'entity': 'spectrum', 'concept_id': 'C1883073', 'confidence': 1.0}, {'entity': 'pityriasis lichenoides chronica', 'concept_id': 'C0162851', 'confidence': 1.0}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'scaly macules', 'concept_id': 'C0332573', 'confidence': 0.7616965174674988}, {'entity': 'papules', 'concept_id': 'C0332563', 'confidence': 0.9999999403953552}], [{'entity': 'histology', 'concept_id': 'C0019638', 'confidence': 1.0}, {'entity': 'pityriasis lichenoides', 'concept_id': 'C0162853', 'confidence': 1.0}, {'entity': 'pleva', 'concept_id': 'C0162852', 'confidence': 1.0}, {'entity': 'pleva', 'concept_id': 'C0162852', 'confidence': 1.0}, {'entity': 'acute', 'concept_id': 'C0205178', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'spongiosis', 'concept_id': 'C0702120', 'confidence': 1.0}, {'entity': 'ballooning', 'concept_id': 'C0004704', 'confidence': 1.0}, {'entity': 'necrosis', 'concept_id': 'C0027540', 'confidence': 1.0}], [{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'clinically documented', 'concept_id': 'C1828480', 'confidence': 0.814785361289978}, {'entity': 'pityriasis lichenoides chronica', 'concept_id': 'C0162851', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_927",
"caption_rating": "8"
},
{
"": "1008513",
"caption": "Tumor is recapitulating fetal fat development.",
"image_path": "pBR26SS0FX8_image_e4af34da-8507-4e4f-a94a-e1471a8a8a63.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Hematopathology', 'Breast pathology']",
"roi_text": "['multi-vacuolated']",
"noisy_text": " or some of these guys are kind of bivaculated or multi-vaculated, but with a tiny little bland nucleus. See, these are multi-bubbly cells, but they just are so little, right? So the idea here is that this tumor is kind of recapitulating what fetal fat looks like during fat development in the fetus. And if you see fetal fat, which I'm sure our pediatric pathology colleague, Yan Hong can speak to, that there are times in early fetal life where the fat can have some similarity to this, that fat in embryology, my basic understanding is it starts out as a spindled precursor to adipocytes, and then it builds up a little lipid and makes a vacuole, and then can make more vacuoles sometimes, and then eventually",
"corrected_text": " or some of these guys are kind of bivacuolated or multi-vacuolated, but with a tiny little bland nucleus. See, these are multi-bubbly cells, but they just are so little, right? So the idea here is that this tumor is kind of recapitulating what fetal fat looks like during fat development in the fetus. And if you see fetal fat, which I'm sure our pediatric pathology colleague, Yan Hong can speak to, that there are times in early fetal life where the fat can have some similarity to this, that fat in embryology, my basic understanding is it starts out as a spindle precursor to adipocytes, and then it builds up a little lipid and makes a vacuole, and then can make more vacuoles sometimes, and then eventually",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'tumor cells', 'concept_id': 'C0431085', 'confidence': 1.0}, {'entity': 'bivacuolated', 'concept_id': 'C0010840', 'confidence': 0.7087458372116089}, {'entity': 'multi-vacuolated', 'concept_id': 'C1513755', 'confidence': 0.6100779175758362}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'bland nucleus', 'concept_id': 'C0007610', 'confidence': 0.7939299941062927}], [{'entity': 'Tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'fetal', 'concept_id': 'C0015965', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_928",
"caption_rating": "7"
},
{
"": "1009441",
"caption": "Whirling pattern can be seen in perineurioma and dermatofibrosarcoma protuberans (DFSP).",
"image_path": "QDb68_G1HR4_image_744a098e-53fa-41a0-8aaf-b32c7771239e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['whirling pattern']",
"noisy_text": " This one's not really showing that but some of them do, they have a lot of whirling pattern. So the two other things that keep in the differential here are perineurioma and also dermatofibrosarcoma protuberans, DFSP, which also has a tends to have a story form or whirled and swirled growth pattern and also has a translocation sarcoma, has very bland spindle cells. Okay, I guess I don't have any immunostains with me to show you today but just briefly the immunostains, most of the immunostains that we use for soft tissue tumors are negative most of the time in low-grade fibromyxoid sarcoma. CD34 is usually negative which is a pretty easy way to separate this from DFSP. The other thing is that low-grade fibromyxoid sarcoma usually is a relatively larger and deep, deep soft tissue below the fascia mass, although there are rare examples that are small and superficial and those seem to be more common in children. But DFSP is essentially always in the skin, the dermis or subcutaneous and rarely ever involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is",
"corrected_text": " This one's not really showing that but some of them do, they have a lot of whirling pattern. So the two other things that keep in the differential here are perineurioma and also dermatofibrosarcoma protuberans, DFSP, which also has a tends to have a story form or whirled and swirled growth pattern and also has a translocation sarcoma, has very bland spindle cells. Okay, I guess I don't have any immunostaining with me to show you today but just briefly the immunostaining, most of the immunostaining that we use for soft tissue tumors are negative most of the time in low-grade fibromyxoid sarcoma. CD34 is usually negative which is a pretty easy way to separate this from DFSP. The other thing is that low-grade fibromyxoid sarcoma usually is a relatively larger and deep, deep soft tissue below the fascia mass, although there are rare examples that are small and superficial and those seem to be more common in children. But DFSP is essentially always in the skin, the dermis or subcutaneous and rarely ever involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is",
"med_umls_ids": "[[{'entity': 'Whirling pattern', 'concept_id': 'C0449774', 'confidence': 0.6110570430755615}, {'entity': 'perineurioma', 'concept_id': 'C0751691', 'confidence': 0.9999999403953552}, {'entity': 'dermatofibrosarcoma protuberans', 'concept_id': 'C0206647', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}], [{'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}, {'entity': 'skin', 'concept_id': 'C0444099', 'confidence': 1.0}, {'entity': 'deep soft tissue', 'concept_id': 'C0225317', 'confidence': 0.7996832728385925}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_929",
"caption_rating": "8"
},
{
"": "1008941",
"caption": "Uniform cells surrounding the edge of the neurofibroma with rosettes, which may indicate a low-grade fibromyxoid sarcoma.",
"image_path": "QDb68_G1HR4_image_fa35112f-0444-4765-b252-414100c399df.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " uniform cells that surround the edge of the collagen rosettes when you see those rosettes in this tumor so collagen rosettes in a fibroblastic tumor should be an instant clue that you're probably dealing with a low-grade fibromyxoid sarcoma but do remember again that some variants of schwannoma can also have rosettes and so be sure not to confuse those immunostains can help you out there so I hope that you like this video and that this helps sort this out again make sure that you've checked out my you know five-minute approach to telling apart low-grade fibromyxoid sarcoma from myxofibrosarcoma comma grade 1 and also watch the full-length feature video about myxofibrosarcoma and then I think after seeing this video and those two videos you should have a really solid handle on how to tell these tumors apart I made these videos and went so in-depth because I find that that pathologists often really struggle with these because the name sounds so much alike and in those of us in soft tissue pathology who publish papers maybe we haven't helped the general pathology public so much by making names that all sound so similar. So I hope the video has helped if you liked it please click like down below and leave comments or questions in the comment section and of course make sure you subscribe to my channel if you haven't yet so that you'll be notified about new videos that I post in the future.",
"corrected_text": " uniform cells that surround the edge of the collagen rosettes when you see those rosettes in this tumor so collagen rosettes in a fibroblastic tumor should be an instant clue that you're probably dealing with a low-grade fibromyxoid sarcoma but do remember again that some variants of schwannoma can also have rosettes and so be sure not to confuse those immunostains can help you out there so I hope that you like this video and that this helps sort this out again make sure that you've checked out my you know five-minute approach to telling apart low-grade fibromyxoid sarcoma from myxofibrosarcoma comma grade 1 and also watch the full-length feature video about myxofibrosarcoma and then I think after seeing this video and those two videos you should have a really solid handle on how to tell these tumors apart I made these videos and went so detailed because I find that that pathologists often really struggle with these because the name sounds so much alike and in those of us in soft tissue pathology who publish papers maybe we haven't helped the general pathology public so much by making names that all sound so similar. So I hope the video has helped if you liked it please click like down below and leave comments or questions in the comment section and of course make sure you subscribe to my channel if you haven't yet so that you'll be notified about new videos that I post in the future.",
"med_umls_ids": "[[{'entity': 'Uniform cells', 'concept_id': 'C0007584', 'confidence': 0.6272867321968079}, {'entity': 'edge', 'concept_id': 'C0205154', 'confidence': 1.0}, {'entity': 'neurofibroma', 'concept_id': 'C0027830', 'confidence': 1.0}, {'entity': 'rosettes', 'concept_id': 'C0035863', 'confidence': 0.8847858905792236}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}], [{'entity': 'Immunohistochemistry', 'concept_id': 'C0021044', 'confidence': 0.9999998807907104}, {'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_930",
"caption_rating": "8"
},
{
"": "1007865",
"caption": "Histopathological description of a targetoid hemosiderotic hemangioma, which can be distinguished from Kaposi\u2019s sarcoma by the absence of plasma cells within the infiltrate and negative HHV8 stain.",
"image_path": "8S4LeiO6Bbk_image_75f8f0dd-6414-408d-ac76-5b6f39d49caf.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['collagen bundles', 'pre-existing vascular spaces', 'plump endothelial cells', 'absence of plasma cells', 'negative HHV8 stain']",
"noisy_text": " between collagen bundles. We even have a little bit of a promontory sign here where we've got these vessels surrounding pre-existing vascular spaces. But unlike the neovascular spaces that we see in Kaposi's sarcoma, the endothelial cells here are a little more plump, and we don't have plasma cells within the infiltrate. And plasma cells within the infiltrate can be very useful in discriminating between this condition and Kaposi's sarcoma. In this particular case, also the HHV8 stain was a negative, which would be positive in Kaposi's sarcoma. So the diagnosis in this case was a targetoid hemocidiotic hemangioma, sometimes known as a hobnail hemangioma. Frequently has a characteristic clinical appearance, occurs commonly",
"corrected_text": " between collagen bundles. We even have a little bit of a promontory sign here where we've got these vessels surrounding pre-existing vascular spaces. But unlike the neovascularization that we see in Kaposi's sarcoma, the endothelial cells here are a little more plump, and we don't have plasma cells within the infiltrate. And plasma cells within the infiltrate can be very useful in discriminating between this condition and Kaposi's sarcoma. In this particular case, also the HHV8 stain was a negative, which would be positive in Kaposi's sarcoma. So the diagnosis in this case was a targetoid hemosiderotic hemangioma, sometimes known as a hobnail hemangioma. Frequently has a characteristic clinical appearance, occurs commonly",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'targetoid hemosiderotic hemangioma', 'concept_id': 'C0346076', 'confidence': 0.9999999403953552}, {'entity': 'Kaposi\u2019s sarcoma', 'concept_id': 'C0036220', 'confidence': 0.9617650508880615}, {'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}]]",
"magnification": "1.0",
"height": "758.0",
"width": "1920.0",
"id": "test_931",
"caption_rating": "9"
},
{
"": "1006828",
"caption": "The presence of sarcoma cells, which are uniform and fibroblastic in appearance.",
"image_path": "QDb68_G1HR4_image_3594f719-d6fd-4c1d-bc83-4aa9c52ac1e9.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Sarcoma cells', 'Fibrous area with delicate collagen.']",
"noisy_text": " So I'm going to go in even higher power to convince you, yes these are sarcoma cells right here. They just don't look very atypical at all. They look bland, they don't usually have pleomorphism, they look uniform, they look very much like each other and look very fibroblastic and again this is, I've talked in other videos this is a true statement about many of the translocation associated sarcomas. They have the same molecular abnormality in every single cell so all the cells look alike. They look monotonous and uniform rather than pleomorphic, okay? So there's a few exceptions to this we'll talk about in a minute but this is the cytologic feature of low grade fibromyxoid sarcoma so that's the fibrous area, delicate collagen kind of",
"corrected_text": " So I'm going to go in even higher power to convince you, yes these are sarcoma cells right here. They just don't look very atypical at all. They look bland, they don't usually have pleomorphism, they look uniform, they look very much like each other and look very fibroblastic and again this is, I've talked in other videos this is a true statement about many of the translocation associated sarcomas. They have the same molecular abnormality in every single cell so all the cells look alike. They look monotonous and uniform rather than pleomorphic, okay? So there's a few exceptions to this we'talk about in a minute but this is the cytologic feature of low grade fibromyxoid sarcoma so that's the fibrous area, delicate collagen kind of",
"med_umls_ids": "[[{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'sarcoma cells', 'concept_id': 'C0024302', 'confidence': 0.7867116332054138}, {'entity': 'uniform', 'concept_id': 'C0205375', 'confidence': 1.0}, {'entity': 'fibroblastic', 'concept_id': 'C0016030', 'confidence': 0.8876925110816956}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}], [{'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_932",
"caption_rating": "8"
},
{
"": "1004844",
"caption": "Superficial and deep perivascular infiltrate present in sections as a vague wedge-shaped configuration.",
"image_path": "8S4LeiO6Bbk_image_9ce3c52a-4c31-4758-b5c6-6541c12d3d6e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Biopsy specimen from the trunk.']",
"noisy_text": " Okay, let's go ahead and move on to slide number nine. This was another example of an interface dermatitis. We have a bisected punch biopsy here. This biopsy specimen was from the trunk and one can see that we've got a superficial and deep perivascular infiltrate present in these sections as a vague wedge-shaped configuration. If we look at the epidermis, we can see, again, there's an obscuration of the normal epidermal junction by bacular change and Apache lymphocytic infiltrate. In this particular instance, there's also a little bit of spongiosis with exocytosis of lymphocytes into widened intracellular spaces, and there are some mounds of perikaratosis within the",
"corrected_text": " Okay, let's go ahead and move on to slide number nine. This was another example of an interface dermatitis. We have a bisected punch biopsy here. This biopsy specimen was from the trunk and one can see that we've got a superficial and deep perivascular infiltrate present in these sections as a vague wedge-shaped configuration. If we look at the epidermis, we can see, again, there's an obscuration of the normal epidermal junction by vacuolar change and Apache lymphocytic infiltrate. In this particular instance, there's also a little bit of spongiosis with exocytosis of lymphocytes into widened intracellular spaces, and there are some mounds of parakeratosis within the",
"med_umls_ids": "[[{'entity': 'Punch biopsy', 'concept_id': 'C0182557', 'confidence': 1.0}, {'entity': 'interface dermatitis', 'concept_id': 'C0262981', 'confidence': 1.0}, {'entity': 'trunk', 'concept_id': 'C0225442', 'confidence': 0.9999999403953552}], [{'entity': 'Superficial', 'concept_id': 'C0205124', 'confidence': 1.0}, {'entity': 'deep perivascular infiltrate', 'concept_id': 'C4531289', 'confidence': 0.8486854434013367}, {'entity': 'sections', 'concept_id': 'C0007876', 'confidence': 0.8770228624343872}, {'entity': 'wedge-shaped configuration', 'concept_id': 'C1695776', 'confidence': 0.6548662185668945}], [{'entity': 'Obscuration', 'concept_id': 'C4100897', 'confidence': 0.8260445594787598}, {'entity': 'vacuolar change', 'concept_id': 'C0010840', 'confidence': 1.0}, {'entity': 'Apache lymphocytic infiltrate', 'concept_id': 'C0333386', 'confidence': 0.8769314885139465}], [{'entity': 'Spongiosis', 'concept_id': 'C0702120', 'confidence': 1.0}, {'entity': 'exocytosis', 'concept_id': 'C0015283', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'intracellular', 'concept_id': 'C0175996', 'confidence': 1.0}, {'entity': 'spaces', 'concept_id': 'C1883067', 'confidence': 0.7782474160194397}, {'entity': 'mounds', 'concept_id': 'C2717795', 'confidence': 0.736616313457489}, {'entity': 'parakeratosis', 'concept_id': 'C0030436', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_933",
"caption_rating": "8"
},
{
"": "1007266",
"caption": "Presence of active inflammation.",
"image_path": "sDFjOtMAYrk_image_1084161e-7caa-402a-825a-a07d77549d1b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['Thick and irregular band with feet-like projections into the lamina propria.']",
"noisy_text": " and some eos. And what else? Yeah, exactly. So the band interrupts inflammatory cells and capillaries, and it's not just the thickness of the band that really catches your eyes, the irregularity of it. So you don't have a thin smooth line anymore. It's just, you know, thick and irregular, just just throwing like feet down into the, into the lamina appropriate. There are also a few lymphocytes in the epithelium, but that's not the main finding. The other thing you might find in some of these is some degree of active inflammation. And let",
"corrected_text": " and some eos. And what else? Yeah, exactly. So the band interrupts inflammatory cells and capillaries, and it's not just the thickness of the band that really catches your eyes, the irregularity of it. So you don't have a thin smooth line anymore. It's just, you know, thick and irregular, just just throwing like feet down into the, into the lamina appropriate. There are also a few lymphocytes in the epithelium, but that's not the main finding. The other thing you might find in some of these is some degree of active inflammation. And let",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'band', 'concept_id': 'C0175723', 'confidence': 1.0}, {'entity': 'inflammatory cells', 'concept_id': 'C0440752', 'confidence': 1.0}, {'entity': 'capillaries', 'concept_id': 'C0006901', 'confidence': 0.9999998807907104}], [{'entity': 'Thick', 'concept_id': 'C1280412', 'confidence': 1.0}, {'entity': 'irregular', 'concept_id': 'C0205271', 'confidence': 1.0}, {'entity': 'projections', 'concept_id': 'C0016538', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'active', 'concept_id': 'C0205177', 'confidence': 1.0}, {'entity': 'inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_934",
"caption_rating": "7"
},
{
"": "1009124",
"caption": "Giant cells are not numerous and there is minimal hemosiderin deposition in this case.",
"image_path": "j_rG5XPImFQ_image_80d9c191-1c69-4c48-b896-3b788cf951ee.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Hematopathology', 'Breast pathology']",
"roi_text": "['multilobulated growth', 'dense fibrosis', 'giant cells', 'multilobulated growth', 'dense fibrosis', 'giant cells']",
"noisy_text": " Mitotic activity can be relatively high, but this on its own should not be concerning for malignant transformation. In this case, you could see that the giant cells were not numerous, and there was minimal hemosiderin deposition. To give you a better sense of the morphologic spectrum of this tumor, I'm going to show a couple more examples. In this example, we still have multilobulated growth and dense fibrosis. However, even at low power, you can see that the giant cells are larger and more numerous than the previous example.",
"corrected_text": " Mitotic activity can be relatively high, but this on its own should not be concerning for malignant transformation. In this case, you could see that the giant cells were not numerous, and there was minimal hemosiderin deposition. To give you a better sense of the morphologic spectrum of this tumor, I'm going to show a couple more examples. In this example, we still have multilobulated growth and dense fibrosis. However, even at low power, you can see that the giant cells are larger and more numerous than the previous example.",
"med_umls_ids": "[[{'entity': 'Mitotic activity', 'concept_id': 'C1334779', 'confidence': 1.0}, {'entity': 'malignant transformation', 'concept_id': 'C0287850', 'confidence': 0.8324378132820129}], [{'entity': 'Giant cells', 'concept_id': 'C0017526', 'confidence': 1.0}, {'entity': 'hemosiderin', 'concept_id': 'C0019113', 'confidence': 1.0}, {'entity': 'deposition', 'concept_id': 'C0333562', 'confidence': 1.0}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}], [{'entity': 'Multilobulated', 'concept_id': 'C4538849', 'confidence': 0.8302288055419922}, {'entity': 'growth', 'concept_id': 'C0018270', 'confidence': 1.0}, {'entity': 'dense fibrosis', 'concept_id': 'C0016059', 'confidence': 0.8111783862113953}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}], [{'entity': 'Giant cells', 'concept_id': 'C0017526', 'confidence': 1.0}, {'entity': 'larger', 'concept_id': 'C0549177', 'confidence': 1.0}, {'entity': 'numerous', 'concept_id': 'C0439064', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_935",
"caption_rating": "9"
},
{
"": "1004846",
"caption": "Spongiosis with exocytosis of lymphocytes into widened intracellular spaces and mounds of parakeratosis are also present.",
"image_path": "8S4LeiO6Bbk_image_9ce3c52a-4c31-4758-b5c6-6541c12d3d6e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Biopsy specimen from the trunk.']",
"noisy_text": " Okay, let's go ahead and move on to slide number nine. This was another example of an interface dermatitis. We have a bisected punch biopsy here. This biopsy specimen was from the trunk and one can see that we've got a superficial and deep perivascular infiltrate present in these sections as a vague wedge-shaped configuration. If we look at the epidermis, we can see, again, there's an obscuration of the normal epidermal junction by bacular change and Apache lymphocytic infiltrate. In this particular instance, there's also a little bit of spongiosis with exocytosis of lymphocytes into widened intracellular spaces, and there are some mounds of perikaratosis within the",
"corrected_text": " Okay, let's go ahead and move on to slide number nine. This was another example of an interface dermatitis. We have a bisected punch biopsy here. This biopsy specimen was from the trunk and one can see that we've got a superficial and deep perivascular infiltrate present in these sections as a vague wedge-shaped configuration. If we look at the epidermis, we can see, again, there's an obscuration of the normal epidermal junction by vacuolar change and Apache lymphocytic infiltrate. In this particular instance, there's also a little bit of spongiosis with exocytosis of lymphocytes into widened intracellular spaces, and there are some mounds of parakeratosis within the",
"med_umls_ids": "[[{'entity': 'Punch biopsy', 'concept_id': 'C0182557', 'confidence': 1.0}, {'entity': 'interface dermatitis', 'concept_id': 'C0262981', 'confidence': 1.0}, {'entity': 'trunk', 'concept_id': 'C0225442', 'confidence': 0.9999999403953552}], [{'entity': 'Superficial', 'concept_id': 'C0205124', 'confidence': 1.0}, {'entity': 'deep perivascular infiltrate', 'concept_id': 'C4531289', 'confidence': 0.8486854434013367}, {'entity': 'sections', 'concept_id': 'C0007876', 'confidence': 0.8770228624343872}, {'entity': 'wedge-shaped configuration', 'concept_id': 'C1695776', 'confidence': 0.6548662185668945}], [{'entity': 'Obscuration', 'concept_id': 'C4100897', 'confidence': 0.8260445594787598}, {'entity': 'vacuolar change', 'concept_id': 'C0010840', 'confidence': 1.0}, {'entity': 'Apache lymphocytic infiltrate', 'concept_id': 'C0333386', 'confidence': 0.8769314885139465}], [{'entity': 'Spongiosis', 'concept_id': 'C0702120', 'confidence': 1.0}, {'entity': 'exocytosis', 'concept_id': 'C0015283', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'intracellular', 'concept_id': 'C0175996', 'confidence': 1.0}, {'entity': 'spaces', 'concept_id': 'C1883067', 'confidence': 0.7782474160194397}, {'entity': 'mounds', 'concept_id': 'C2717795', 'confidence': 0.736616313457489}, {'entity': 'parakeratosis', 'concept_id': 'C0030436', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_936",
"caption_rating": "9"
},
{
"": "1007970",
"caption": "The atypia seen in this case is consistent with STOMP, stromal tumor of uncertain malignant potential.",
"image_path": "iklRyY1nBIE_image_25025022-8442-4585-8463-496487442b19.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['basal cell hyperplasia', 'infiltrating between benign glands', 'STOMP', 'prostatic stroma of sarcoma', 'HMB45 melanin', 'S100', 'STAT6']",
"noisy_text": " Something else you may have observed with this case is the fact that it's not just a stroma process. It looks like there's something else going on in the glands, too. And in the glands, it's almost like there's a crosstalk between the stroma process and the glands. The glands are benign, but they actually have what looks like basal cell hyperplasia in areas. And that's not uncommon with this entity. It is not unusual to have this entity, actually, with basal cell hyperplasia. The other observation I want to bring to your attention is the fact that this process is going in between benign glands, which means that it's almost respecting the benign glands next door. Because there are a number of processes that would destroy the adjacent benign glands and basically push them aside. But this process actually respects the benign glands, in quotes, and is actually going in between them, infiltrating in between them. And that's a clue to the diagnosis. Because as I hinted earlier, when you talk of tumors of the specialized prosthetic stroma, there are two main entities you think about. One is the so-called STOMP, stromal tumor of unsaturated malignant potential. And the other entity at the other extreme is the so-called prosthetic stroma of sarcoma. Some argue that there's some relationship between both of them that are in the spectrum. But what you're looking at right now in this case, based on what I've shown you, this type of atypia, it almost looks simplistic. It has this degenerative type of look to it. We are not seeing mitotic activity. For something this ugly or that looks this nasty, you'll expect to see necrosis, mitotic activity, and even destruction of the adjacent glands. But we're not seeing that. And that's kind of a perfect picture for so-called STOMP, stromal tumor of unsaturated malignant potential. As I said earlier, there's a relationship between this entity and prosthetic stroma of sarcoma. To start with, STOMPs can recur. About 15% of STOMPs can recur months or years after the initial resection. But about 15% to 20% of STOMPs may progress or may be associated with adjacent prosthetic stroma of sarcoma. So that's a very important thing to know. Because STOMP itself, as the name implies, is of unsaturated malignant potential. So it should not be downplayed. Because some of you may ask me, how do I sign all these cases? It's very important in your comments to document what I just said, that about 15% of these, if it's just STOMP is here on the H&E, nothing else, it's important to document that about 15% would recur. And more importantly, it's important to document that about 15% to 20% of these may be associated with or progress to prosthetic stroma of sarcoma. So it's not a case of they excise this and they leave the patient alone. They need to follow up these patients very closely. So that's very important to document in the report. So some of you may ask, OK, so what stains do we do for these cases? Obviously, you want to exclude a number of things. We talked about melanoma and other things. So you want to exclude those. So obviously, HMB45 melanin, those will be negative. Vimentin, which nobody uses anymore, is actually positive in this entity. PR could also be positive in this entity. Plus or minus CD34, plus or minus Desmin SMA, plus or minus ER may be positive, but it's usually negative. The pertinent negative stains are S100. I talked about the melanoma markers. And STAT6 is also negative. So it's very important to know that. So this is a stromal tumor of uncertain malignant potential. There have been a number of names for this entity over the years.",
"corrected_text": " Something else you may have observed with this case is the fact that it's not just a stroma process. It looks like there's something else going on in the glands, too. And in the glands, it's almost like there's a crosstalk between the stroma process and the glands. The glands are benign, but they actually have what looks like basal cell hyperplasia in areas. And that's not uncommon with this entity. It is not unusual to have this entity, actually, with basal cell hyperplasia. The other observation I want to bring to your attention is the fact that this process is going in between benign glands, which means that it's almost respecting the benign glands next door. Because there are a number of processes that would destroy the adjacent benign glands and basically push them aside. But this process actually respects the benign glands, in quotes, and is actually going in between them, infiltrating in between them. And that's a clue to the diagnosis. Because as I hinted earlier, when you talk of tumors of the specialized prosthetic stroma, there are two main entities you think about. One is the so-called STOMP, stromal tumor of unsaturated malignant potential. And the other entity at the other extreme is the so-called prosthetic stroma of sarcoma. Some argue that there's some relationship between both of them that are in the spectrum. But what you're looking at right now in this case, based on what I've shown you, this type of atypia, it almost looks simplistic. It has this degenerative type of look to it. We are not seeing mitotic activity. For something this ugly or that looks this nasty, you'expect to see necrosis, mitotic activity, and even destruction of the adjacent glands. But we're not seeing that. And that's kind of a perfect picture for so-called STOMP, stromal tumor of unsaturated malignant potential. As I said earlier, there's a relationship between this entity and prosthetic stroma of sarcoma. To start with, STOMPs can recur. About 15% of STOMPs can recur months or years after the initial resection. But about 15% to 20% of STOMPs may progress or may be associated with adjacent prosthetic stroma of sarcoma. So that's a very important thing to know. Because STOMP itself, as the name implies, is of unsaturated malignant potential. So it should not be downplayed. Because some of you may ask me, how do I sign all these cases? It's very important in your comments to document what I just said, that about 15% of these, if it's just STOMP is here on the H&E, nothing else, it's important to document that about 15% would recur. And more importantly, it's important to document that about 15% to 20% of these may be associated with or progress to prosthetic stroma of sarcoma. So it's not a case of they excise this and they leave the patient alone. They need to follow up these patients very closely. So that's very important to document in the report. So some of you may ask, OK, so what stains do we do for these cases? Obviously, you want to exclude a number of things. We talked about melanoma and other things. So you want to exclude those. So obviously, HMB45 melanin, those will be negative. Vimentin, which nobody uses anymore, is actually positive in this entity. PR could also be positive in this entity. Plus or minus CD34, plus or minus Desmin SMA, plus or minus ER may be positive, but it's usually negative. The pertinent negative stains are S100. I talked about the melanoma markers. And STAT6 is also negative. So it's very important to know that. So this is a stromal tumor of uncertain malignant potential. There have been a number of names for this entity over the years.",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'basal cell', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'benign glands', 'concept_id': 'C1301287', 'confidence': 0.726940393447876}, {'entity': 'entity', 'concept_id': 'C1551338', 'confidence': 1.0}], [{'entity': 'process', 'concept_id': 'C1184743', 'confidence': 1.0}, {'entity': 'infiltrating', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'benign glands', 'concept_id': 'C1301287', 'confidence': 0.726940393447876}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'atypia', 'concept_id': 'C0741302', 'confidence': 0.9999999403953552}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'consistent with', 'concept_id': 'C0332290', 'confidence': 1.0}, {'entity': 'STOMP', 'concept_id': 'C0056167', 'confidence': 0.6245664358139038}, {'entity': 'stromal tumor', 'concept_id': 'C0879615', 'confidence': 1.0}, {'entity': 'malignant', 'concept_id': 'C0205282', 'confidence': 1.0}, {'entity': 'potential', 'concept_id': 'C3245505', 'confidence': 1.0}], [{'entity': 'STOMPs', 'concept_id': 'C0577018', 'confidence': 0.6140404343605042}, {'entity': 'recur', 'concept_id': 'C0034897', 'confidence': 0.9999999403953552}, {'entity': 'progress', 'concept_id': 'C1272688', 'confidence': 1.0}, {'entity': 'prostatic stroma', 'concept_id': 'C1521760', 'confidence': 0.9999999403953552}, {'entity': 'sarcoma', 'concept_id': 'C1261473', 'confidence': 1.0}], [{'entity': 'Stains', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'entities', 'concept_id': 'C0424215', 'confidence': 0.7521668672561646}, {'entity': 'HMB45', 'concept_id': 'C1440756', 'confidence': 1.0}, {'entity': 'melanin', 'concept_id': 'C0025196', 'confidence': 1.0}, {'entity': 'S100', 'concept_id': 'C3273837', 'confidence': 1.0}, {'entity': 'STAT6', 'concept_id': 'C0297890', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_937",
"caption_rating": "9"
},
{
"": "1007401",
"caption": "The biopsy from the urethra shows urethritis cystica et glandularis, with dissecting pools of mucin that do not necessarily indicate malignancy. Goblet cell formation is visible, indicating the initial stages of mucinous adenocarcinoma.",
"image_path": "iklRyY1nBIE_image_ea3ae54e-461c-4f5c-baf6-17d730741228.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['Urethritis cystica et glandularis', 'Goblet cell formation', 'Urethritis cystica et glandularis', 'Goblet cell formation']",
"noisy_text": " So this was a biopsy from the urethra. And all you can see here is urethritis cystica et glandularis. They're dissecting pools of mucin, but that doesn't always mean there's a malignant process going on. So that's something else one needs to be careful about. There are some areas here that are very concerning. But the reason why I'm showing you this slide is just to show you the overlying urethritis cystic ed glandularis intestinal type. You can actually see some goblet cell formation there. So that's how it starts. And then it progresses to this, where you're not just seeing the surface urethelium involved by this misnose adenocarcinoma, but it's actually beginning to invade the subepithelial connective tissue. It's beginning",
"corrected_text": " So this was a biopsy from the urethra. And all you can see here is urethritis cystica et glandularis. They're dissecting pools of mucin, but that doesn't always mean there's a malignant process going on. So that's something else one needs to be careful about. There are some areas here that are very concerning. But the reason why I'm showing you this slide is just to show you the overlying urethritis cystic ed glandularis intestinal type. You can actually see some goblet cell formation there. So that's how it starts. And then it progresses to this, where you're not just seeing the surface urothelium involved by this mucinous adenocarcinoma, but it's actually beginning to invade the lamina propria. It's beginning",
"med_umls_ids": "[[{'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}, {'entity': 'urethra', 'concept_id': 'C0041967', 'confidence': 1.0}, {'entity': 'urethritis cystica', 'concept_id': 'C3272656', 'confidence': 0.9999998807907104}, {'entity': 'glandularis', 'concept_id': 'C1231964', 'confidence': 0.8643958568572998}, {'entity': 'dissecting pools', 'concept_id': 'C0205239', 'confidence': 0.6663767695426941}, {'entity': 'mucin', 'concept_id': 'C0026682', 'confidence': 1.0}, {'entity': 'malignancy', 'concept_id': 'C0006826', 'confidence': 1.0}, {'entity': 'Goblet', 'concept_id': 'C0506994', 'confidence': 0.8473865389823914}, {'entity': 'cell formation', 'concept_id': 'C2936218', 'confidence': 0.9225678443908691}, {'entity': 'visible', 'concept_id': 'C0205379', 'confidence': 0.9999998807907104}, {'entity': 'stages', 'concept_id': 'C1306673', 'confidence': 0.9999999403953552}, {'entity': 'mucinous adenocarcinoma', 'concept_id': 'C0007130', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_938",
"caption_rating": "8"
},
{
"": "1008641",
"caption": "Active inflammation in the stomach, with neutrophils present on the epithelium.",
"image_path": "r7OA0Trj5hQ_image_543a0feb-40d4-4b35-a6e4-da5a8bdec291.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['H. pylori in the luminal area or lumen', 'Neutrophils on the epithelium indicating active inflammation', 'H. pylori in the luminal area or lumen', 'Goblet cells in the surface epithelium.', 'Neutrophils on the epithelium indicating active inflammation', 'H. pylori in the luminal area or lumen', 'Goblet cells in the surface epithelium.']",
"noisy_text": " this is equivalent to cryptitis in the colon. In the stomach, we call it pit, so I don't want to call it pititis. It doesn't sound very great, but you can see the neutrophils sitting on the epithelium. So this is an active inflammation. Here, now we are coming to cytology. You see in the intra-luminal area or in the lumen, you see a lot of comma-shaped rods sitting on the epithelium, not going into the epithelium. So these are all the H. pylori in the oil immersion. Here, the surface epithelium shows goblet cells, and these are all biopsies",
"corrected_text": " this is equivalent to cryptitis in the colon. In the stomach, we call it pit, so I don't want to call it pititis. It doesn't sound very great, but you can see the neutrophils sitting on the epithelium. So this is an active inflammation. Here, now we are coming to cytology. You see in the luminal area or in the lumen, you see a lot of comma-shaped rods sitting on the epithelium, not going into the epithelium. So these are all the H. pylori in the oil immersion. Here, the surface epithelium shows goblet cells, and these are all biopsies",
"med_umls_ids": "[[{'entity': 'Active inflammation', 'concept_id': 'C0333361', 'confidence': 1.0}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}, {'entity': 'neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'H. pylori', 'concept_id': 'C0079488', 'confidence': 1.0}, {'entity': 'luminal area', 'concept_id': 'C0524462', 'confidence': 0.7778207659721375}, {'entity': 'lumen', 'concept_id': 'C0524461', 'confidence': 0.9999998807907104}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}], [{'entity': 'Surface epithelium', 'concept_id': 'C1182809', 'confidence': 1.0}, {'entity': 'goblet cells', 'concept_id': 'C0506994', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_939",
"caption_rating": "9"
},
{
"": "1008225",
"caption": "Salt and pepper chromatin is a defining feature of a neuroendocrine tumor.",
"image_path": "Wiyo6taYRF4_image_f2fd3cc2-b10f-44d2-aa3a-167b1cde6571.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Hematopathology', 'Neuropathology', 'Cytopathology']",
"roi_text": "['neuroendocrine carcinoma', 'hyperchromatic nuclei', 'vesicular nuclei', 'nucleoli', 'salt and pepper chromatin', 'nucleoli', 'salt and pepper chromatin']",
"noisy_text": " and pepper like copper chromatin, that means you're telling that this is most likely a neuroendocrine kind of a carcinoma. So those are the different types of nuclei that we have seen. Again, to go back at the reference, we are going to look at the plasma cell. In the plasma cell, we can easily identify the hetero and the vesicular areas, that is heterochromatin and nucleomatin. If the cell is entirely composed of heterochromatin, it will be very dark-staining. And this is called as hyperchromatic nuclei. If it is composed of lightly-stained nuclei, lightly-stained areas, then it is called vesicular nuclei. A vesicular nuclei is usually accompanied by a nucleoli. And if you have very finely granular dark and light areas, then it is called as salt and pepper chromatin. And these are the defining features for a neuroendocrine tumor. Now, once we have understood the staining pattern of the",
"corrected_text": " and pepper like copper chromatin, that means you're telling that this is most likely a neuroendocrine kind of a carcinoma. So those are the different types of nuclei that we have seen. Again, to go back at the reference, we are going to look at the plasma cell. In the plasma cell, we can easily identify the hetero and the vesicular areas, that is heterochromatin and nucleoplasm. If the cell is entirely composed of heterochromatin, it will be very hyperchromatic. And this is called as hyperchromatic nuclei. If it is composed of lightly-stained areas, lightly-stained areas, then it is called vesicular nuclei. A vesicular nuclei is usually accompanied by a nucleoli. And if you have very finely granular dark and light areas, then it is called as salt and pepper chromatin. And these are the defining features for a neuroendocrine tumor. Now, once we have understood the staining pattern of the",
"med_umls_ids": "[[{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'pepper-like copper chromatin', 'concept_id': 'C0453397', 'confidence': 0.5605897903442383}, {'entity': 'neuroendocrine carcinoma', 'concept_id': 'C0206695', 'confidence': 1.0}], [{'entity': 'nuclei', 'concept_id': 'C0007610', 'confidence': 0.8452459573745728}, {'entity': 'observed', 'concept_id': 'C1441672', 'confidence': 1.0}, {'entity': 'hyperchromatic', 'concept_id': 'C0333911', 'confidence': 1.0}, {'entity': 'vesicular nuclei', 'concept_id': 'C2325471', 'confidence': 0.7651268839836121}], [{'entity': 'Heterochromatin', 'concept_id': 'C0019397', 'confidence': 1.0}, {'entity': 'nucleoplasm', 'concept_id': 'C0682537', 'confidence': 1.0}, {'entity': 'identified', 'concept_id': 'C0205396', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}], [{'entity': 'Vesicular nuclei', 'concept_id': 'C2325471', 'confidence': 0.7651268839836121}, {'entity': 'nucleoli', 'concept_id': 'C0007609', 'confidence': 0.8710004091262817}], [{'entity': 'Salt', 'concept_id': 'C0036140', 'confidence': 1.0}, {'entity': 'pepper chromatin', 'concept_id': 'C0008546', 'confidence': 0.7025638818740845}, {'entity': 'neuroendocrine tumor', 'concept_id': 'C0206754', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1152.0",
"id": "test_940",
"caption_rating": "9"
},
{
"": "1008319",
"caption": "Rosacea can present with multiple different histologic reaction patterns including papulopustular rosacea and telangiectatic type of rosacea.",
"image_path": "LlPaENuqzVQ_image_4619fb4f-a724-4098-99be-ac57f694e50b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['face', 'follicular pustule', 'histiocytes', 'lymphocytes', 'face', 'follicular pustule', 'histiocytes', 'lymphocytes']",
"noisy_text": " Oh, maybe there are some there on the other slide. But, oh, yeah, there's some. Not a lot, but, you know, there's mostly histiocytes predominated with lymphocytes. There's a couple of eos, but it's not... There aren't a lot. So that kind of made me think of granulomatous rosacea. Good. Excellent. That's exactly what it should make you think of. Very, very good. That's exactly what this is. So the face helps you, right? You're not going to see this on somebody's trunk. The follicular pustule helps too, right? Because rosacea can give you multiple different histologic reaction patterns. What are some of the forms of rosacea? So we've got two forms here. We've got papulopustular rosacea. We've got granulomatous rosacea. What are a couple other forms of rosacea? You could just have an ET type of just, you know, kind of like telangiectasia. Yes, good. The telangiectatic type of rosacea. What's one other one that we get sometimes? I guess there's other... I mean, I don't",
"corrected_text": " Oh, maybe there are some there on the other slide. But, oh, yeah, there's some. Not a lot, but, you know, there's mostly histiocytes predominated with lymphocytes. There's a couple of eos, but it's not... There aren't a lot. So that kind of made me think of granulomatous rosacea. Good. Excellent. That's exactly what it should make you think of. Very, very good. That's exactly what this is. So the face helps you, right? You're not going to see this on somebody's trunk. The follicular pustule helps too, right? Because rosacea can give you multiple different histologic reaction patterns. What are some of the forms of rosacea? So we've got two forms here. We've got papulopustular rosacea. We've got granulomatous rosacea. What are a couple other forms of rosacea? You could just have an ET type of just, you know, kind of like telangiectasia. Yes, good. The telangiectatic type of rosacea. What's one other one that we get sometimes? I guess there's other... I mean, I don't",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'skin condition', 'concept_id': 'C1719933', 'confidence': 1.0}, {'entity': 'predominance', 'concept_id': 'C1835590', 'confidence': 0.8840479850769043}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}], [{'entity': 'Granulomatous rosacea', 'concept_id': 'C1275718', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'Rosacea', 'concept_id': 'C0035854', 'confidence': 1.0}, {'entity': 'multiple', 'concept_id': 'C0439064', 'confidence': 1.0}, {'entity': 'histologic reaction', 'concept_id': 'C0205462', 'confidence': 0.8118124008178711}, {'entity': 'papulopustular rosacea', 'concept_id': 'C1449853', 'confidence': 1.0}, {'entity': 'telangiectatic type', 'concept_id': 'C4014149', 'confidence': 0.7599172592163086}, {'entity': 'rosacea', 'concept_id': 'C0035854', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_941",
"caption_rating": "8"
},
{
"": "1008364",
"caption": "The absence of neutrophils and foam cells distinguishes this from a verruciform xanthoma.",
"image_path": "8S4LeiO6Bbk_image_525c93d7-23ef-4276-b0ce-6a5662640cb6.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['columns and mounds of parakeratosis within the stratum corneum', 'dyskeratotic cells within the underlying epidermis', 'papillary dermis between these zones', 'no identifiable foam cells present within the papillary dermis', 'columns and mounds of parakeratosis within the stratum corneum', 'dyskeratotic cells within the underlying epidermis', 'papillary dermis between these zones', 'no identifiable foam cells present within the papillary dermis']",
"noisy_text": " and if we move to higher power, we can confirm these findings. Lymphocytes, dilated vessels, papillomatosis, and epidermal hyperplasia. There are discrete columns and mounds of pericaratosis within the stratum corneum and some dyskeratotic cells within the underlying epidermis. One of the things when one sees these these columns of bright pink pericaratosis that one might think about would be a verruciform xanthoma because you'll remember we tend to get these vertical columns of pericaratosis kind of extending down to a v-shaped imagination of the epidermis. We have that here but one thing that we don't have here that one typically sees in a verruciform xanthoma is the presence of neutrophils and mixed with the pericaratotic cells and also if we look in the dermal papillae between these zones, there are really no identifiable foam cells present within the dermal papillae. Looking over at the far edge of this",
"corrected_text": " and if we move to higher power, we can confirm these findings. Lymphocytes, dilated vessels, papillomatosis, and epidermal hyperplasia. There are discrete columns and mounds of parakeratosis within the stratum corneum and some dyskeratotic cells within the underlying epidermis. One of the things when one sees these these columns of bright pink parakeratosis that one might think about would be a verruciform xanthoma because you'remember we tend to get these vertical columns of pericaratosis kind of extending down to a v-shaped imagination of the epidermis. We have that here but one thing that we don't have here that one typically sees in a verruciform xanthoma is the presence of neutrophils and mixed with the parakeratotic cells and also if we look in the dermal papillae between these zones, there are really no identifiable foam cells present within the dermal papillae. Looking over at the far edge of this",
"med_umls_ids": "[[{'entity': 'histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'findings', 'concept_id': 'C2607943', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'dilated vessels', 'concept_id': 'C0424830', 'confidence': 0.8255378603935242}, {'entity': 'papillomatosis', 'concept_id': 'C0205875', 'confidence': 1.0}, {'entity': 'epidermal hyperplasia', 'concept_id': 'C0263641', 'confidence': 1.0}], [{'entity': 'discrete columns', 'concept_id': 'C0227428', 'confidence': 0.6879350543022156}, {'entity': 'mounds', 'concept_id': 'C2717795', 'confidence': 0.736616313457489}, {'entity': 'parakeratosis', 'concept_id': 'C0030436', 'confidence': 1.0}, {'entity': 'stratum corneum', 'concept_id': 'C0221921', 'confidence': 1.0}, {'entity': 'dyskeratotic cells', 'concept_id': 'C1512098', 'confidence': 0.8970272541046143}, {'entity': 'epidermis', 'concept_id': 'C0014520', 'confidence': 1.0}], [{'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'neutrophils', 'concept_id': 'C0027950', 'confidence': 1.0}, {'entity': 'foam cells', 'concept_id': 'C0016390', 'confidence': 1.0}, {'entity': 'verruciform xanthoma', 'concept_id': 'C0346054', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_942",
"caption_rating": "8"
},
{
"": "1009492",
"caption": "The presence of a large cellular fibrohistiocytic infiltrate with collagen trapping and ring siderophages is indicative of a hemosiderotic or aneurysmal type of dermatofibroma, also known as a sclerosing hemangioma variant of a dermatofibroma. These lesions have a tendency to persist or recur if incompletely excised.",
"image_path": "8S4LeiO6Bbk_image_7e3835f4-1d1b-47bf-8ec0-cc8848e903a0.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Large cellular fibrohistiocytic infiltrate with collagen trapping and ring siderophages', 'Hemosiderotic or aneurysmal type of dermatofibroma', 'Punch biopsy specimen', 'Large cellular fibrohistiocytic infiltrate with collagen trapping and ring siderophages', 'Hemosiderotic or aneurysmal type of dermatofibroma', 'Punch biopsy specimen']",
"noisy_text": " know, we're not seeing any necrosis or an appreciable number of mitotic figures. And this large cellular fibrohystic-acidic infiltrate, again with the collagen trapping and ring siderophages out of the periphery, seems to be compressing the fat. And the constellation of features in these sections is pathognomonic, of course, or a hemociderotic or aneurysmal type of dermatofibroma, also known as a sclerosing hemangioma variant of a dermatofibroma. This is a type of cellular dermatofibroma. These lesions can get quite large and if incompletely excised do have a tendency to persist or recur. So good idea to completely excise these because they're certainly not going to go away on their own. A classic example, very commonly asked on boards and usually spoilers that you could expect in a question given this slide would include things like a blue nevus or melanoma or even nodular cap issues. So be familiar with the features of the hemociderotic variant of a dermatofibroma. Moving on to slide number five. This was kind of a cool case. We have a bisected punch biopsy specimen here. If we move into higher power, we can see that the epidermis",
"corrected_text": " know, we're not seeing any necrosis or an appreciable number of mitotic figures. And this large cellular fibrohystic-acidic infiltrate, again with the collagen trapping and ring siderophages out of the periphery, seems to be compressing the fat. And the constellation of features in these sections is pathognomonic, of course, or a hemosiderotic or aneurysmal type of dermatofibroma, also known as a sclerosing hemangioma variant of a dermatofibroma. This is a type of cellular dermatofibroma. These lesions can get quite large and if incompletely excised do have a tendency to persist or recur. So good idea to completely excise these because they're certainly not going to go away on their own. A classic example, very commonly asked on boards and usually spoilers that you could expect in a question given this slide would include things like a blue nevus or melanoma or even nodular cap issues. So be familiar with the features of the hemosiderotic variant of dermatofibroma of a dermatofibroma. Moving on to slide number five. This was kind of a cool case. We have a bisected punch biopsy specimen here. If we move into higher power, we can see that the epidermis",
"med_umls_ids": "[[{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'cellular fibrohistiocytic infiltrate', 'concept_id': 'C0019618', 'confidence': 0.7253735065460205}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'trapping', 'concept_id': 'C0282665', 'confidence': 0.8904784917831421}, {'entity': 'ring siderophages', 'concept_id': 'C1136253', 'confidence': 0.6553963422775269}, {'entity': 'hemosiderotic', 'concept_id': 'C0019114', 'confidence': 0.7758374810218811}, {'entity': 'aneurysmal type', 'concept_id': 'C0439651', 'confidence': 0.8459930419921875}, {'entity': 'dermatofibroma', 'concept_id': 'C0002991', 'confidence': 1.0}, {'entity': 'sclerosing', 'concept_id': 'C0036426', 'confidence': 0.833010733127594}, {'entity': 'hemangioma', 'concept_id': 'C0018916', 'confidence': 1.0}, {'entity': 'variant', 'concept_id': 'C0205419', 'confidence': 1.0}, {'entity': 'dermatofibroma', 'concept_id': 'C0002991', 'confidence': 1.0}, {'entity': 'lesions', 'concept_id': 'C0221198', 'confidence': 1.0}, {'entity': 'excised', 'concept_id': 'C1444670', 'confidence': 0.7215964794158936}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_943",
"caption_rating": "10"
},
{
"": "1004808",
"caption": "Lipophagic cells with lipid vacuoles and hemocyanin, including ringed siderophages.",
"image_path": "8S4LeiO6Bbk_image_da91943b-95f1-427f-85ac-c15b9d31eae8.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['collagen balls', 'spindle-shaped cells', 'lipophagic cells', 'ringed siderophages', 'pigmented histiocytes', 'collagen balls', 'spindle-shaped cells', 'lipophagic cells', 'ringed siderophages', 'pigmented histiocytes']",
"noisy_text": " these collagen balls that are being surrounded by cells that have a somewhat spindled shape. The nuclei are spindled over our fusiform and they're kind of wrapping around these collagen bundles. In this same area, we can begin to see some lipophagia. So we see these large histiocytes containing lipid. Some of them are multi-nucleated and some of these are actually ringed siderophages. So we see large multi-nucleated histiocytes with a ring of nuclei and they contain not only lipid vacuoles but hemocentaurant. And these are particularly common in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes",
"corrected_text": " these collagen balls that are being surrounded by cells that have a somewhat spindle-shaped. The nuclei are spindle-shaped over our fusiform and they're kind of wrapping around these collagen bundles. In this same area, we can begin to see some lipophagic. So we see these large histiocytes containing lipid. Some of them are multi-nucleated and some of these are actually ringed siderophages. So we see large multinucleated histiocytes with a ring of nuclei and they contain not only lipid vacuoles but hemosiderin. And these are particularly common in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'collagen balls', 'concept_id': 'C0009325', 'confidence': 0.7217866778373718}, {'entity': 'surrounded', 'concept_id': 'C1282914', 'confidence': 1.0}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}], [{'entity': 'Lipophagic cells', 'concept_id': 'C0007584', 'confidence': 0.5962335467338562}, {'entity': 'lipid vacuoles', 'concept_id': 'C1179126', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'ringed', 'concept_id': 'C0325501', 'confidence': 0.77345871925354}, {'entity': 'siderophages', 'concept_id': 'C1136253', 'confidence': 0.7251443266868591}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_944",
"caption_rating": "9"
},
{
"": "1008516",
"caption": "Dysgerminoma is a highly malignant tumor that commonly spreads by lymphatics.",
"image_path": "3mRB9j0eyVM_image_93b859d1-6fae-4171-93a6-905bac877aae.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gynecologic', 'Hematopathology', 'Soft tissue']",
"roi_text": "['Schiller-Duval-Dewall bodies in endodermal sinus tumor', 'lymphatics in dysgerminoma', 'glomerulite structure of endodermal sinus tumor']",
"noisy_text": " Then other malignant young cell tumors include the yolk sap tumor that is highly malignant. It is also named as endodermal sinus tumor. It affects the young age and these are partly solid and they secrete alpha-phetoprotein. This is my dear student the histological picture of yolk sap tumor. The typical finding of yolk sap tumor is that it contains the specialized type of bodies that are named as Shiller-Dewall bodies. That Shiller-Dewall bodies are the bodies that comprise of the central capillary, central this vascular area and it is surrounded by the tumor cells. Then a space and that space is again surrounded by the tumor cells. So it presents as the glomerulite structure like glomerulus like that is just like as the as we see the glomerulus of a kidney. So glomerulite bodies that are found and that are typical of the yolk sap tumor and these glomerulite bodies are named as Shiller-Dewall bodies. So these are the typical identification feature of the yolk sap. Then is the dysgerminoma that is very common highly malignant tumor and usually it spreads by lymphatics. It is very radio",
"corrected_text": " Then other malignant young cell tumors include the endodermal sinus tumor that is highly malignant. It is also named as endodermal sinus tumor. It affects the young age and these are partly solid and they secrete alpha-fetoprotein. This is my dear student the histological picture of endodermal sinus tumor. The typical finding of endodermal sinus tumor is that it contains the specialized type of bodies that are named as Schiller-Duval-Dewall bodies. That Schiller-Duval-Dewall bodies are the bodies that comprise of the central capillary, central this vascular area and it is surrounded by the tumor cells. Then a space and that space is again surrounded by the tumor cells. So it presents as the glomerulite structure like glomerulus like that is just like as the as we see the glomerulus of a kidney. So glomerulite bodies that are found and that are typical of the endodermal sinus tumor and these glomerulite bodies are named as Schiller-Duval-Dewall bodies. So these are the typical identification feature of the yolk sap. Then is the dysgerminoma that is very common highly malignant tumor and usually it spreads by lymphatics. It is very radio",
"med_umls_ids": "[[{'entity': 'Endodermal sinus tumor', 'concept_id': 'C0014145', 'confidence': 1.0}, {'entity': 'malignant tumor', 'concept_id': 'C0006826', 'confidence': 1.0}, {'entity': 'young', 'concept_id': 'C0332239', 'confidence': 1.0}, {'entity': 'individuals', 'concept_id': 'C0027361', 'confidence': 0.8766164779663086}, {'entity': 'solid', 'concept_id': 'C0205208', 'confidence': 1.0}, {'entity': 'secretes', 'concept_id': 'C1327616', 'confidence': 0.8702053427696228}, {'entity': 'alpha-fetoprotein', 'concept_id': 'C0002210', 'confidence': 1.0}], [{'entity': 'histological picture', 'concept_id': 'C0205462', 'confidence': 0.785039484500885}, {'entity': 'endodermal sinus tumor', 'concept_id': 'C0014145', 'confidence': 1.0}, {'entity': 'Schiller-Duval-Dewall bodies', 'concept_id': 'C1710022', 'confidence': 0.7228695750236511}, {'entity': 'bodies', 'concept_id': 'C0242821', 'confidence': 1.0}, {'entity': 'central capillary surrounded', 'concept_id': 'C0006901', 'confidence': 0.5871620774269104}, {'entity': 'tumor cells', 'concept_id': 'C0431085', 'confidence': 1.0}], [{'entity': 'Dysgerminoma', 'concept_id': 'C0013377', 'confidence': 1.0}, {'entity': 'malignant tumor', 'concept_id': 'C0006826', 'confidence': 1.0}, {'entity': 'spreads', 'concept_id': 'C0564319', 'confidence': 0.8124106526374817}, {'entity': 'lymphatics', 'concept_id': 'C0024235', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "960.0",
"id": "test_945",
"caption_rating": "8"
},
{
"": "1008600",
"caption": "Lamina propria on the right is typically busier with eosinophils, lymphocytes, and plasma cells.",
"image_path": "sDFjOtMAYrk_image_87eda8ad-6e79-47c1-a274-11131c97a2ea.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['lamina propria', 'inflammatory cells', 'eosinophils', 'lymphocytes', 'plasma cells', 'basement membrane', 'lamina propria', 'inflammatory cells', 'eosinophils', 'lymphocytes', 'plasma cells', 'basement membrane']",
"noisy_text": " segment and shows a lamina propria pretty devoid of... You see a couple of inflammatory cells here and there, but not really a lot in the way of lymphocytes, plasma cells, and actually eos are rare. But when you get biopsies, and I'm sorry I didn't bring one from... That was on the left. If you used to have something from the right, your lamina propria is typically busier, and I allow for quite a few eosinophils, lymphocytes, and plasma cells. The other thing that you want to keep in mind is... Let me just go back to the H and E for a second. The basement membrane, I will",
"corrected_text": " segment and shows a lamina propria pretty devoid of... You see a couple of inflammatory cells here and there, but not really a lot in the way of lymphocytes, plasma cells, and actually eos are rare. But when you get biopsies, and I'm sorry I didn't bring one from... That was on the left. If you used to have something from the right, your lamina propria is typically busier, and I allow for quite a few eosinophils, lymphocytes, and plasma cells. The other thing that you want to keep in mind is... Let me just go back to the H and E for a second. The basement membrane, I will",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'segment', 'concept_id': 'C0441635', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'inflammatory cells', 'concept_id': 'C0440752', 'confidence': 1.0}], [{'entity': 'Lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'right', 'concept_id': 'C0205090', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'plasma cells', 'concept_id': 'C0032112', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_946",
"caption_rating": "8"
},
{
"": "1006514",
"caption": "The lesion appears neoplastic and epithelial in nature",
"image_path": "LlPaENuqzVQ_image_cc92051f-2349-4017-bf3d-e70cda207b5a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['The lesion is not well circumscribed and appears asymmetrical', 'The size of the lesion is large', 'The lesion is not well circumscribed and appears asymmetrical', 'The size of the lesion is large']",
"noisy_text": " So they basically took the elliptical excision. They cut it into bread loaves and put it all on one slide. So that's how they did this in this case, because yeah, if you do a shave, how frequently do you get down to the bottom of the subcutaneous fat? That's pretty rare. So this is an excisional biopsy. Good. And are you dealing with an inflammatory or neoplastic process? Looks more neoplastic. Good, good. Epithelial or non-epithelial? Epithelioid. Good, epithelial. Benign or malignant? It's not very well prescribed. You can do it low power, isn't it? It's phenomenal. You can really get it down pretty well if you just apply the criteria. So you like benign or malignant here? It's not very well circumscribed, and it looks like there's some erosion on top. That may be from a prior biopsy, interestingly enough. But yeah, look at its symmetry. Is this symmetrical? Not really. No, no, no. It's pretty big. This is",
"corrected_text": " So they basically took the elliptical excision. They cut it into bread loaves and put it all on one slide. So that's how they did this in this case, because yeah, if you do a shave, how frequently do you get down to the bottom of the subcutaneous fat? That's pretty rare. So this is an excisional biopsy. Good. And are you dealing with an inflammatory or neoplastic process? Looks more neoplastic. Good, good. Epithelial or non-epithelial? epithelial. Good, epithelial. Benign or malignant? It's not very well prescribed. You can do it low power, isn't it? It's phenomenal. You can really get it down pretty well if you just apply the criteria. So you like benign or malignant here? It's not very well circumscribed, and it looks like there's some erosion on top. That may be from a prior biopsy, interestingly enough. But yeah, look at its symmetry. Is this symmetrical? Not really. No, no, no. It's pretty big. This is",
"med_umls_ids": "[[{'entity': 'Elliptical excision', 'concept_id': 'C1707902', 'confidence': 0.8901858329772949}, {'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}], [{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'neoplastic', 'concept_id': 'C1709160', 'confidence': 0.9999999403953552}, {'entity': 'epithelial', 'concept_id': 'C0221908', 'confidence': 1.0}], [{'entity': 'Malignancy', 'concept_id': 'C0006826', 'confidence': 1.0}, {'entity': 'determined with', 'concept_id': 'C0521095', 'confidence': 0.8590028285980225}, {'entity': 'certainty', 'concept_id': 'C0205423', 'confidence': 1.0}], [{'entity': 'erosion', 'concept_id': 'C0333307', 'confidence': 1.0}, {'entity': 'top', 'concept_id': 'C1420726', 'confidence': 1.0}, {'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_947",
"caption_rating": "8"
},
{
"": "1004650",
"caption": "Clefting between epithelium and stroma is not seen in these lesions, unlike basal cell carcinoma.",
"image_path": "LlPaENuqzVQ_image_6ba963b0-96f9-4e11-99d7-c8d4db19a672.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['Trichofolliculoma with a cyst and miniaturized hair follicles', 'fibrous stroma', 'clefting between epithelium and stroma']",
"noisy_text": " This is sort of a tricofolliculoma cut adjacent to the really the central cyst. And the tricofolliculoma has got a little cyst with these little miniaturized hair follicles that are radiating from the central cyst component of the lesion. So this is off to the side of it. But you can see that these follicular neoplasms, they pretty much commonly do have this stroma that you see with it that's more fibrous as opposed to fibromucinous. And that's helpful. It's not a criterion for the diagnosis necessarily every time, but it's a helpful finding when you see it because you don't usually get clefting between the epithelium and the stroma in these lesions as opposed to a basal cell carcinoma where you do. So that's a tricofolliculoma kind of cut to the side. OK, let's",
"corrected_text": " This is sort of a trichofolliculoma cut adjacent to the really the central cyst. And the trichofolliculoma has got a little cyst with these little miniaturized hair follicles that are radiating from the central cyst component of the lesion. So this is off to the side of it. But you can see that these follicular neoplasms, they pretty much commonly do have this stroma that you see with it that's more fibrous as opposed to fibromyxoid. And that's helpful. It's not a criterion for the diagnosis necessarily every time, but it's a helpful finding when you see it because you don't usually get clefting between the epithelium and the stroma in these lesions as opposed to a basal cell carcinoma where you do. So that's a trichofolliculoma kind of cut to the side. OK, let's",
"med_umls_ids": "[[{'entity': 'Trichofolliculoma', 'concept_id': 'C0334262', 'confidence': 1.0}, {'entity': 'cyst', 'concept_id': 'C0010709', 'confidence': 1.0}, {'entity': 'miniaturized hair follicles', 'concept_id': 'C0221971', 'confidence': 0.7287319302558899}, {'entity': 'adjacent', 'concept_id': 'C0205117', 'confidence': 1.0}, {'entity': 'central cyst', 'concept_id': 'C0205099', 'confidence': 0.7124271988868713}], [{'entity': 'Follicular', 'concept_id': 'C0439682', 'confidence': 1.0}, {'entity': 'neoplasms', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'fibrous stroma', 'concept_id': 'C1180207', 'confidence': 0.8035051226615906}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'Clefting', 'concept_id': 'C4021813', 'confidence': 0.8906428217887878}, {'entity': 'epithelium', 'concept_id': 'C0014609', 'confidence': 1.0}, {'entity': 'stroma', 'concept_id': 'C0927195', 'confidence': 1.0}, {'entity': 'lesions', 'concept_id': 'C0221198', 'confidence': 1.0}, {'entity': 'basal cell carcinoma', 'concept_id': 'C0007117', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_948",
"caption_rating": "9"
},
{
"": "1005147",
"caption": "The narrator is discussing pigmented Bowen\u2019s disease, which can resemble other benign skin conditions but must be checked for orderly maturation to differentiate it from squamous cell carcinoma.",
"image_path": "8S4LeiO6Bbk_image_836ea94b-1bc5-4588-b069-005e968b8c4b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['pigmented Bowen\u2019s disease']",
"noisy_text": " of pigmented Bowen's disease or pigmented squamous cell carcinoma. One could see similar changes in lesions too of boenoid papillosis and if this was one of many or a few papules on the genitalia one would have to keep boenoid papillosis and the differential as well here but this is one of these lesions that kind of is a fooler because it has a benign silhouette, resembles a psoriasis form dermatitis or even an inflamed pigmented seborrheic keratosis but it always behooves you to go down and check to make sure that you've got orderly maturation because architecturally Bowen's disease can resemble a benign keratosis. So, pigmented Bowen's disease in this case. Moving on to slide number eight. Slide number eight is the first of two interface dermatitis that we're",
"corrected_text": " of pigmented Bowen's disease or pigmented squamous cell carcinoma. One could see similar changes in lesions too of bowenoid papulosis and if this was one of many or a few papules on the genitalia one would have to keep bowenoid papulosis and the differential as well here but this is one of these lesions that kind of is a fooler because it has a benign silhouette, resembles a psoriasis form dermatitis or even an inflamed pigmented seborrheic keratosis but it always behooves you to go down and check to make sure that you've got orderly maturation because architecturally squamous cell carcinoma's disease can resemble a benign keratosis. So, pigmented Bowen's disease in this case. Moving on to slide number eight. Slide number eight is the first of two interface dermatitis that we're",
"med_umls_ids": "[[{'entity': 'narrator', 'concept_id': 'C1135957', 'confidence': 0.7711340188980103}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'Bowen\u2019s disease', 'concept_id': 'C0006079', 'confidence': 0.9730859994888306}, {'entity': 'benign', 'concept_id': 'C0205183', 'confidence': 1.0}, {'entity': 'maturation', 'concept_id': 'C0678723', 'confidence': 1.0}, {'entity': 'differentiate', 'concept_id': 'C0205615', 'confidence': 0.9999998807907104}, {'entity': 'squamous cell carcinoma', 'concept_id': 'C0007137', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_949",
"caption_rating": "7"
},
{
"": "1009384",
"caption": "The presence of eosinophils or prominent eosinophils can indicate mycophenol. Neuroendocrine cell aggregates and apoptotic bodies are not present in mycophenol.",
"image_path": "sDFjOtMAYrk_image_84730f38-cd87-4e07-a673-99516f299c59.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['Presence of eosinophils or prominent eosinophils', 'Neuroendocrine cell aggregates', 'Apoptotic bodies']",
"noisy_text": " Is there a number? I think it's more than 15 per high power field. Typically, I just say, you know, the presence of eosinophils or prominent eosinophils favors microphenol. The other thing is you don't see any neuroendocrine cell aggregates. Those you see in GVHD. The other thing is you don't see apoptotic micro abscesses. Those will be in GVHD and you will not see them in microphenol. And then, you know, actually, the main finding, let's talk about the main finding, which is what? Yeah, exactly. And let's see if we can find some right there. Yeah. Apoptotic bodies. Yeah. So I find that",
"corrected_text": " Is there a number? I think it's more than 15 per high power field. Typically, I just say, you know, the presence of eosinophils or prominent eosinophils favors mycophenol. The other thing is you don't see any neuroendocrine cell aggregates. Those you see in GVHD. The other thing is you don't see apoptotic bodies. Those will be in GVHD and you will not see them in mycophenol. And then, you know, actually, the main finding, let's talk about the main finding, which is what? Yeah, exactly. And let's see if we can find some right there. Yeah. Apoptotic bodies. Yeah. So I find that",
"med_umls_ids": "[[{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'mycophenol', 'concept_id': 'C0883242', 'confidence': 0.8315404653549194}, {'entity': 'Neuroendocrine cell', 'concept_id': 'C1518275', 'confidence': 1.0}, {'entity': 'aggregates', 'concept_id': 'C0205418', 'confidence': 1.0}, {'entity': 'apoptotic bodies', 'concept_id': 'C3269134', 'confidence': 1.0}, {'entity': 'mycophenol', 'concept_id': 'C0883242', 'confidence': 0.8315404653549194}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_950",
"caption_rating": "8"
},
{
"": "1008108",
"caption": "Differentiating between myxoma and cellular intramuscular myxoma can be challenging on needle biopsy.",
"image_path": "QDb68_G1HR4_image_3fd48468-516d-41b7-b65c-1e2b8862f938.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " And on a needle biopsy I think that can be challenging. So I think usually with some experience you can tell them apart on H and E most of the time but when I have any doubt I just do a MUC4 stain. The MUC4 is negative and on a needle it looks like a myxoma with some kind of fibrous or a little bit more cellular areas and then I just say that it's probably a cellular intramuscular myxoma. So I think MUC4 is a really helpful stain and if you don't have it in your lab you can send out and get it done at outside labs too. So again when you have the whole tumor removed it's pretty easy to tell that this is not an intramuscular myxoma. Intramuscular myxoma",
"corrected_text": " And on a needle biopsy I think that can be challenging. So I think usually with some experience you can tell them apart on H and E most of the time but when I have any doubt I just do a MUC4 stain. The MUC4 is negative and on a needle it looks like a myxoma with some kind of fibrous or a little bit more cellular areas and then I just say that it's probably a cellular intramuscular myxoma. So I think MUC4 is a really helpful stain and if you don't have it in your lab you can send out and get it done at outside labs too. So again when you have the whole tumor removed it's pretty easy to tell that this is not an intramuscular myxoma. Intramuscular myxoma",
"med_umls_ids": "[[{'entity': 'Differentiating', 'concept_id': 'C0205615', 'confidence': 1.0}, {'entity': 'myxoma', 'concept_id': 'C0027149', 'confidence': 1.0}, {'entity': 'cellular intramuscular myxoma', 'concept_id': 'C1334260', 'confidence': 0.8910117149353027}, {'entity': 'needle biopsy', 'concept_id': 'C0005560', 'confidence': 1.0}], [{'entity': 'MUC4', 'concept_id': 'C1417496', 'confidence': 0.9999999403953552}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}], [{'entity': 'Negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'MUC4', 'concept_id': 'C1417496', 'confidence': 0.9999999403953552}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'cellular intramuscular myxoma', 'concept_id': 'C1334260', 'confidence': 0.8910117149353027}], [{'entity': 'Complete', 'concept_id': 'C0205197', 'confidence': 0.9999998807907104}, {'entity': 'differentiate', 'concept_id': 'C0205615', 'confidence': 0.9999998807907104}, {'entity': 'myxoma', 'concept_id': 'C0027149', 'confidence': 1.0}, {'entity': 'cellular intramuscular myxoma', 'concept_id': 'C1334260', 'confidence': 0.8910117149353027}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_951",
"caption_rating": "8"
},
{
"": "1004619",
"caption": "The hamartoma involves both the epithelial component and a fibrous sheath around the hair follicle.",
"image_path": "LlPaENuqzVQ_image_a9bad7d7-e820-43ea-879e-fb44eed5e7d3.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['miniaturized hair follicle', 'mantle zone', 'stem cell area', 'bulge', 'apocrine gland', 'sebaceous gland', 'hamartoma', 'fibrous sheath', 'bulge']",
"noisy_text": " Like, it looks more like if there's, if I'm going to guess, like there's, I feel like there's a little bit of like, I would guess more like towards the, like a glandular. Yeah, well, it's, it's, it's a little miniaturized hair follicle. Nope. It's like this little guy here. It's like a little tiny follicle. And there's, we always think of three parts of the hair follicle. We think of the infundibulum, the isthmus, and we think of the inferior portion, but there's a very important part right around the isthmic part, just beneath the follicle, the infundibulum, and then where the inferior portion begins, that's known as the mantle zone. And that's kind of where all the action is. That's really kind of a stem cell area that sometimes those cells will form a little bulge there and they actually will end up forming an apocrine gland. Sometimes they'll end up forming a sebaceous gland. Sometimes they, you know, will just, they'll form, sometimes they form a little hammertoma, like you see right here. And they actually end up getting you this little sort of primitive little, it almost looks like a mini hair follicle that didn't really form. And then when you look at a hair follicle, it's comprised not only of the epithelial component, but there's also a periepithelial sheath around it, a fibrous sheath around the hair follicle. And so this is a hammertoma that involves both of those. So it's got a fibrous element to it. And then",
"corrected_text": " Like, it looks more like if there's, if I'm going to guess, like there's, I feel like there's a little bit of like, I would guess more like towards the, like a glandular. Yeah, well, it's, it's, it's a little miniaturized hair follicle. Nope. It's like this little guy here. It's like a little tiny follicle. And there's, we always think of three parts of the hair follicle. We think of the infundibulum, the isthmus, and we think of the inferior portion, but there's a very important part right around the isthmic part, just beneath the follicle, the infundibulum, and then where the inferior portion begins, that's known as the mantle zone. And that's kind of where all the action is. That's really kind of a stem cell area that sometimes those cells wiform a little bulge there and they actually wiend up forming an apocrine gland. Sometimes they'end up forming a sebaceous gland. Sometimes they, you know, will just, they'form, sometimes they form a little hamartoma, like you see right here. And they actually end up getting you this little sort of primitive little, it almost looks like a mini hair follicle that didn't really form. And then when you look at a hair follicle, it's comprised not only of the epithelial component, but there's also a periepithelial sheath around it, a fibrous sheath around the hair follicle. And so this is a hamartoma that involves both of those. So it's got a fibrous element to it. And then",
"med_umls_ids": "[[{'entity': 'narrator', 'concept_id': 'C1135957', 'confidence': 0.7711340188980103}, {'entity': 'miniaturized', 'concept_id': 'C0872350', 'confidence': 0.8111259341239929}, {'entity': 'hair follicle', 'concept_id': 'C0221971', 'confidence': 1.0}, {'entity': 'stem cell', 'concept_id': 'C0038250', 'confidence': 1.0}, {'entity': 'mantle zone', 'concept_id': 'C1512987', 'confidence': 1.0}], [{'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'mantle', 'concept_id': 'C0232445', 'confidence': 0.8497024178504944}, {'entity': 'zone', 'concept_id': 'C1710706', 'confidence': 1.0}, {'entity': 'bulge', 'concept_id': 'C0038999', 'confidence': 0.9999999403953552}, {'entity': 'apocrine gland', 'concept_id': 'C0003584', 'confidence': 0.9999998807907104}, {'entity': 'sebaceous gland', 'concept_id': 'C0036505', 'confidence': 1.0}, {'entity': 'hamartoma', 'concept_id': 'C0018552', 'confidence': 0.9999999403953552}], [{'entity': 'hamartoma', 'concept_id': 'C0018552', 'confidence': 0.9999999403953552}, {'entity': 'epithelial component', 'concept_id': 'C1707933', 'confidence': 0.8783122897148132}, {'entity': 'fibrous sheath', 'concept_id': 'C1185724', 'confidence': 1.0}, {'entity': 'hair follicle', 'concept_id': 'C0221971', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_952",
"caption_rating": "9"
},
{
"": "1006031",
"caption": "Subepidermal bullous lesion resembling bullous pemphigoid under the microscope, likely pemphigoid gestation in a pregnant woman.",
"image_path": "udoW6VSqsm4_image_6f8b09d3-0b63-4ad7-b0a9-acf69e1eb6f5.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['subepidermal bullous lesion', 'bullous pemphigoid', 'microscope', 'pregnant woman', 'immunofluorescence pattern', 'Ig', 'C3', 'Ig']",
"noisy_text": " So EBA, DH, PCT. You don't have to go through the entire... I'm just subepidermal. I'm just going through them. I don't know what's the... What if this is a 25-year-old pregnant woman? Oh, gestational. Yeah, pemphigoid gestation. And that's what this is in this case. It looks exactly like bullous pemphigoid under the microscope. You can't tell it apart. So always think of it. And what's the immunofluorescence pattern that we can see? So you would see Ig, not Ag? No Ig at all. No, okay, no. But what do you see? I'm not sure. Anybody know? C3. Linear complement",
"corrected_text": " So EBA, DH, PCT. You don't have to go through the entire... I'm just subepidermal. I'm just going through them. I don't know what's the... What if this is a 25-year-old pregnant woman? Oh, gestational. Yeah, pemphigoid gestation. And that's what this is in this case. It looks exactly like bullous pemphigoid under the microscope. You can't tell it apart. So always think of it. And what's the immunofluorescence pattern that we can see? So you would see Ig, not Ag? No Ig at all. No, okay, no. But what do you see? I'm not sure. Anybody know? C3. Linear complement",
"med_umls_ids": "[[{'entity': 'Subepidermal', 'concept_id': 'C0221935', 'confidence': 0.8599841594696045}, {'entity': 'bullous lesion', 'concept_id': 'C0005758', 'confidence': 1.0}, {'entity': 'bullous pemphigoid', 'concept_id': 'C0030805', 'confidence': 0.9999999403953552}, {'entity': 'microscope', 'concept_id': 'C0181839', 'confidence': 1.0}, {'entity': 'pemphigoid', 'concept_id': 'C0030805', 'confidence': 0.9999999403953552}, {'entity': 'gestation', 'concept_id': 'C0032961', 'confidence': 1.0}, {'entity': 'pregnant woman', 'concept_id': 'C0033011', 'confidence': 1.0}], [{'entity': 'Immunofluorescence pattern', 'concept_id': 'C0016318', 'confidence': 0.8741495609283447}, {'entity': 'absence', 'concept_id': 'C0332197', 'confidence': 1.0}, {'entity': 'Ig', 'concept_id': 'C0021027', 'confidence': 1.0}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'C3', 'concept_id': 'C1305853', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_953",
"caption_rating": "8"
},
{
"": "1006028",
"caption": "Compressed vascular channels are present at the periphery of the tumor.",
"image_path": "8S4LeiO6Bbk_image_aa903496-ae7f-4150-9b54-0225f8d20fbe.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['dilated vascular channels', 'papillary projections', 'enlarged endothelial cells', 'compressed vascular channels', 'extravasated erythrocytes']",
"noisy_text": " which will slowly risk halt. These lesions will stain, frequently with CD34, but also are strongly positive for D240. So they probably are of lymphatic origin rather than vascular origin. What one looks for is a biphasic vascular tumor with this central area characterized by these dilated vascular channels. Let's look at the bottom piece, which frequently do contain these papillary projections, which protrude into the lumina, these plump endothelial cells, and then at the periphery, more compressed vascular channels, which dissect between collagen bundles. And it's at the periphery one frequently sees extravasated erythrocytes, siderophages, and",
"corrected_text": " which will slowly risk halt. These lesions will stain, frequently with CD34, but also are strongly positive for D240. So they probably are of lymphatic origin rather than vascular origin. What one looks for is a biphasic vascular tumor with this central area characterized by these dilated vascular channels. Let's look at the bottom piece, which frequently do contain these papillary projections, which protrude into the lumina, these plump endothelial cells, and then at the periphery, more compressed vascular channels, which dissect between collagen bundles. And it's at the periphery one frequently sees extravasated erythrocytes, siderophages, and",
"med_umls_ids": "[[{'entity': 'Lesions', 'concept_id': 'C0221198', 'confidence': 1.0}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}, {'entity': 'CD34', 'concept_id': 'C0054953', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'D240', 'concept_id': 'C3766973', 'confidence': 0.5323090553283691}, {'entity': 'lymphatic origin', 'concept_id': 'C0229889', 'confidence': 0.7706887125968933}, {'entity': 'vascular origin', 'concept_id': 'C0395959', 'confidence': 0.7819716334342957}], [{'entity': 'biphasic', 'concept_id': 'C0205184', 'confidence': 1.0}, {'entity': 'characterized', 'concept_id': 'C1880022', 'confidence': 1.0}, {'entity': 'dilated', 'concept_id': 'C0700124', 'confidence': 0.9999999403953552}, {'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}, {'entity': 'central area', 'concept_id': 'C0929543', 'confidence': 0.8492603302001953}], [{'entity': 'Papillary projections', 'concept_id': 'C0016538', 'confidence': 0.7451471090316772}, {'entity': 'bottom piece', 'concept_id': 'C1511276', 'confidence': 0.722324788570404}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}], [{'entity': 'Enlarged endothelial cells', 'concept_id': 'C0423263', 'confidence': 0.7785332202911377}, {'entity': 'papillary projections', 'concept_id': 'C0016538', 'confidence': 0.7451471090316772}], [{'entity': 'Compressed vascular channels', 'concept_id': 'C1336948', 'confidence': 0.5993747711181641}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}], [{'entity': 'Extravasated', 'concept_id': 'C0015376', 'confidence': 0.868863582611084}, {'entity': 'erythrocytes', 'concept_id': 'C0014772', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_954",
"caption_rating": "8"
},
{
"": "1006991",
"caption": "Inflammatory colonic pathology can present with varying degrees of inflammation.",
"image_path": "sDFjOtMAYrk_image_757283d5-c995-4a15-9f3b-7b4fcc051194.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "[]",
"noisy_text": " is probably STI. And I said, well, it's really, really inflamed for STI. And lo and behold, she was right. The patient had positive nucleic acid amplification testing for chlamydia. Plus, he had a history of syphilis in the past. So this is a chlamydia proctitis. And this just goes to show you how typically we say in STI proctitis, inflammation is mild to at most moderate, but you can see anything and everything under the sun when it comes to inflammatory colonic pathology and just keep an open mind. Yeah. And I'll be the first to admit that the history really, really helped in this case. No. Yes. Yes. We did immunostains to rule out CMB and",
"corrected_text": " is probably STI. And I said, well, it's really, really inflamed for STI. And lo and behold, she was right. The patient had positive nucleic acid amplification testing for chlamydia. Plus, he had a history of syphilis in the past. So this is a chlamydia proctitis. And this just goes to show you how typically we say in STI proctitis, inflammation is mild to at most moderate, but you can see anything and everything under the sun when it comes to inflammatory colonic pathology and just keep an open mind. Yeah. And I'll be the first to admit that the history really, really helped in this case. No. Yes. Yes. We did immunostains to rule out CMB and",
"med_umls_ids": "[[{'entity': 'Patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'nucleic acid amplification testing', 'concept_id': 'C0200932', 'confidence': 0.938366174697876}, {'entity': 'chlamydia', 'concept_id': 'C0008148', 'confidence': 1.0}, {'entity': 'chlamydia proctitis', 'concept_id': 'C0149856', 'confidence': 1.0}], [{'entity': 'Inflammatory', 'concept_id': 'C0333348', 'confidence': 1.0}, {'entity': 'pathology', 'concept_id': 'C0030664', 'confidence': 1.0}, {'entity': 'degrees', 'concept_id': 'C0449286', 'confidence': 1.0}, {'entity': 'inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}], [{'entity': 'History', 'concept_id': 'C0019664', 'confidence': 1.0}, {'entity': 'diagnosing', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'STI', 'concept_id': 'C0036916', 'confidence': 1.0}, {'entity': 'proctitis', 'concept_id': 'C0033246', 'confidence': 0.9999999403953552}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_955",
"caption_rating": "8"
},
{
"": "1006844",
"caption": "Presence of atypical cells with hyperchromatic nuclei inside blood vessels, possibly indicating inflammation secondary to a tumor or lymphoma.",
"image_path": "LlPaENuqzVQ_image_5b1ef3bd-4451-46c6-bba5-df94b4856a3c.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['lined by endothelium', 'blood vessels', 'atypical cells with hyperchromatic nuclei', 'intravascular', 'intravascular']",
"noisy_text": " And maybe that's lined by endothelium. So it's in the vessels. Yeah, there's another area right there. So this is not an easy one. This is probably more a third year diagnosis, but there's definitely something within the blood vessels here. So the inflammation is probably happening secondary to that. This is, whoa, these cells don't belong here. And, you know, they're sitting inside these blood vessels and they look atypical. There's like hyperchromatic nuclei here. They vary in size and shape. Like intravascular, it doesn't, like lymphoma? I mean, the only thing I think of where it's like, you don't",
"corrected_text": " And maybe that's lined by endothelium. So it's in the vessels. Yeah, there's another area right there. So this is not an easy one. This is probably more a third year diagnosis, but there's definitely something within the blood vessels here. So the inflammation is probably happening secondary to that. This is, whoa, these cells don't belong here. And, you know, they're sitting inside these blood vessels and they look atypical. There's like hyperchromatic nuclei here. They vary in size and shape. Like intravascular, it doesn't, like lymphoma? I mean, the only thing I think of where it's like, you don't",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'atypical cells', 'concept_id': 'C0333865', 'confidence': 1.0}, {'entity': 'hyperchromatic nuclei', 'concept_id': 'C3553776', 'confidence': 1.0}, {'entity': 'blood vessels', 'concept_id': 'C0005847', 'confidence': 1.0}, {'entity': 'inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}, {'entity': 'secondary to', 'concept_id': 'C0175668', 'confidence': 1.0}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'lymphoma', 'concept_id': 'C0024299', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_956",
"caption_rating": "8"
},
{
"": "1008819",
"caption": "Description of nuclear placement in xanthoma and signet ring cells. Diagnosis of gastric xanthoma and poorly differentiated signet cell carcinoma.",
"image_path": "r7OA0Trj5hQ_image_a32621aa-8935-441d-a1ac-e48a230d2a50.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['centrally placed nucleus', 'peripherally pushed nucleus', 'gastric xanthoma', 'signet ring cells', 'poorly differentiated signet cell carcinoma', 'centrally placed nucleus', 'peripherally pushed nucleus', 'gastric xanthoma', 'signet ring cells', 'poorly differentiated signet cell carcinoma', 'centrally placed nucleus', 'peripherally pushed nucleus', 'gastric xanthoma', 'signet ring cells', 'poorly differentiated signet cell carcinoma']",
"noisy_text": " most of the time centrally placed nucleus. Sometimes it is pushed to the periphery. The central nuclear placement is very important for a diagnosis of xanthoma. For a signet cells, it will be predominantly peripherally pushed nucleus. And when you have doubt, you do a CD68, which will be strongly positive. And so this is a gastric xanthoma. Here, it is more like a signet cells. And when you do cytokeratin, it will all be positive. So it's a poorly differentiated signet cell carcinoma. And there are only three types of pathologists in the world. And this, I got it again from Twitter, I think from",
"corrected_text": " most of the time centrally placed nucleus. Sometimes it is pushed to the periphery. The central nuclear placement is very important for a diagnosis of xanthoma. For a signet cells, it will be predominantly peripherally pushed nucleus. And when you have doubt, you do a CD68, which will be strongly positive. And so this is a gastric xanthoma. Here, it is more like a signet cells. And when you do cytokeratin, it will all be positive. So it's a poorly differentiated signet cell carcinoma. And there are only three types of pathologists in the world. And this, I got it again from Twitter, I think from",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'nuclear', 'concept_id': 'C0521447', 'confidence': 1.0}, {'entity': 'xanthoma', 'concept_id': 'C0302314', 'confidence': 1.0}, {'entity': 'signet ring cells', 'concept_id': 'C0333727', 'confidence': 1.0}, {'entity': 'Diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'gastric xanthoma', 'concept_id': 'C1282522', 'confidence': 1.0}, {'entity': 'poorly differentiated', 'concept_id': 'C0205617', 'confidence': 1.0}, {'entity': 'signet cell carcinoma', 'concept_id': 'C0206696', 'confidence': 0.9410539865493774}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_957",
"caption_rating": "8"
},
{
"": "1008381",
"caption": "Invasive urethral carcinoma involving the prostate with colonization.",
"image_path": "iklRyY1nBIE_image_d8f95d8f-96e0-4889-9a62-34c9265898a1.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['Invasive urethral carcinoma involving the prostate.', 'Possible origin of the carcinoma from the prosthetic urethra or bladder.']",
"noisy_text": " So this is an invasive component. So it's very important to document that. So you can't just say urethral carcinoma involving the prostate, you need to say there's a lot of colonization. But you need to also make it clear that there's an invasive component. Now the next question some of you may ask me is, OK, so where is this coming from? Is this coming from the prosthetic urethra? Is this coming from the bladder? And sometimes you can't tell. And it's very important, to be honest, in your report, especially if it's a small biopsy or a top sample, where you can't see urethral carcinoma inside the component, that it could be arising from the prosthetic urethra. But you cannot exclude the possibility of this arising from the bladder. It's very important to document that. Even if you see an incisor component, that does not exclude that it's coming from the bladder. Because sometimes you can have secondary tumors colonize the surface and mimic a primary lesion. So that's an important point to keep in mind. So that was an interesting case I thought I'd share. We're going to move on to case nine shortly. Case nine is a 45-year-old gentleman that presented with a positive digital rectal examination and elevated PSA levels. So remember that age is just 45. I also shared this with you. I think",
"corrected_text": " So this is an invasive component. So it's very important to document that. So you can't just say urethral carcinoma involving the prostate, you need to say there's a lot of colonization. But you need to also make it clear that there's an invasive component. Now the next question some of you may ask me is, OK, so where is this coming from? Is this coming from the prosthetic urethra? Is this coming from the bladder? And sometimes you can't tell. And it's very important, to be honest, in your report, especially if it's a small biopsy or a top sample, where you can't see urethral carcinoma inside the component, that it could be arising from the prosthetic urethra. But you cannot exclude the possibility of this arising from the bladder. It's very important to document that. Even if you see an incisor component, that does not exclude that it's coming from the bladder. Because sometimes you can have secondary tumors colonize the surface and mimic a primary lesion. So that's an important point to keep in mind. So that was an interesting case I thought I'd share. We're going to move on to case nine shortly. Case nine is a 45-year-old gentleman that presented with a positive digital rectal examination and elevated PSA levels. So remember that age is just 45. I also shared this with you. I think",
"med_umls_ids": "[[{'entity': 'Invasive', 'concept_id': 'C0205281', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'colonization', 'concept_id': 'C4289767', 'confidence': 1.0}], [{'entity': 'document', 'concept_id': 'C1301746', 'confidence': 1.0}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}, {'entity': 'component', 'concept_id': 'C0449432', 'confidence': 1.0}, {'entity': 'origin', 'concept_id': 'C0079946', 'confidence': 1.0}, {'entity': 'carcinoma', 'concept_id': 'C0007097', 'confidence': 1.0}], [{'entity': 'Secondary tumors', 'concept_id': 'C0027627', 'confidence': 0.9999999403953552}, {'entity': 'colonize', 'concept_id': 'C3829074', 'confidence': 0.6422675251960754}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'primary', 'concept_id': 'C0205225', 'confidence': 1.0}, {'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_958",
"caption_rating": "8"
},
{
"": "1007244",
"caption": "Some glands are negative for basal cell markers while others are patchy positive, but all glands have similar cytologic features in the nucleus and cytoplasm, indicating partial atrophy.",
"image_path": "iklRyY1nBIE_image_694f7b6d-9bbc-4534-8a4a-7484cd76c906.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['negative for basal cell markers', 'patchy positive for basal cell markers', 'similar cytologic features', 'partial atrophy', 'partial atrophic hyperplasia', 'inflammation', 'well circumscribed cluster of glands', 'negative for basal cell markers', 'patchy positive for basal cell markers', 'similar cytologic features', 'partial atrophy', 'partial atrophic hyperplasia', 'inflammation', 'well circumscribed cluster of glands']",
"noisy_text": " But some cases are tricky like this one, where some of the glands are completely negative for basal cell markers, while others are patchy positive for basal cell markers. But once you recognize on the H and E that both, you know, all these glands have similar cytologic features, both in the nucleus and the cytoplasm, that should make your life very easy. So this was a very good case of partial atrophy. I have some other cases I'll share with you very quickly. Similar scenario, but with a few differences. So this is one case. This is another case. There's partial atrophic hyperplasia over here with some inflammation. But if you come to this area over here, again, you see a fairly well circumscribed cluster of glands. And if",
"corrected_text": " But some cases are tricky like this one, where some of the glands are completely negative for basal cell markers, while others are patchy positive for basal cell markers. But once you recognize on the H and E that both, you know, all these glands have similar cytologic features, both in the nucleus and the cytoplasm, that should make your life very easy. So this was a very good case of partial atrophy. I have some other cases I'share with you very quickly. Similar scenario, but with a few differences. So this is one case. This is another case. There's partial atrophic hyperplasia over here with some inflammation. But if you come to this area over here, again, you see a fairly well circumscribed cluster of glands. And if",
"med_umls_ids": "[[{'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'basal cell', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'markers', 'concept_id': 'C0181734', 'confidence': 0.890313982963562}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}, {'entity': 'cytologic features', 'concept_id': 'C0205471', 'confidence': 0.7179956436157227}, {'entity': 'nucleus', 'concept_id': 'C0007610', 'confidence': 1.0}, {'entity': 'cytoplasm', 'concept_id': 'C0010834', 'confidence': 1.0}, {'entity': 'partial', 'concept_id': 'C0728938', 'confidence': 1.0}, {'entity': 'atrophy', 'concept_id': 'C0333641', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_959",
"caption_rating": "8"
},
{
"": "1004608",
"caption": "Inclusion body fibromatosis can be deforming if present in large numbers.",
"image_path": "8S4LeiO6Bbk_image_8e12c438-65b7-4f22-b03f-1a98c212c8f2.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "[]",
"noisy_text": " and these can actually, if they're present in large enough number, be deforming. This also goes by the name inclusion body fibromatosis, and if you ever see it on a pick list, what you want to do is go down on high power and look for the inclusions. This is kind of a high-power recognition diagnosis, but high yield. Just a beautiful example. We don't see biopsies very often of this condition. Slide number 11. Again, kind of switching gears here. We have a bisectant pudge biopsy specimen. This was also from the trunk. And as we",
"corrected_text": " and these can actually, if they're present in large enough number, be deforming. This also goes by the name inclusion body fibromatosis, and if you ever see it on a pick list, what you want to do is go down on high power and look for the inclusions. This is kind of a high-power recognition diagnosis, but high yield. Just a beautiful example. We don't see biopsies very often of this condition. Slide number 11. Again, kind of switching gears here. We have a desmoplastic fibroblastoma biopsy specimen. This was also from the trunk. And as we",
"med_umls_ids": "[[{'entity': 'Inclusion body fibromatosis', 'concept_id': 'C1318562', 'confidence': 0.9999999403953552}, {'entity': 'deforming', 'concept_id': 'C0333067', 'confidence': 1.0}, {'entity': 'numbers', 'concept_id': 'C0237753', 'confidence': 1.0}], [{'entity': 'Inclusion body fibromatosis', 'concept_id': 'C1318562', 'confidence': 0.9999999403953552}, {'entity': 'high-power recognition diagnosis', 'concept_id': 'C0524637', 'confidence': 0.5715622305870056}], [{'entity': 'Biopsies', 'concept_id': 'C0005558', 'confidence': 1.0}, {'entity': 'condition', 'concept_id': 'C0012634', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_960",
"caption_rating": "8"
},
{
"": "1004438",
"caption": "There are zones of pleomorphism and spindle cells in some areas.",
"image_path": "LlPaENuqzVQ_image_0827e0c8-1f0d-4227-b777-830b8dac8a2d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " and then it becomes much more aggressive. So that's why I'm going to do them with soft tissue. You have to think more of geography. You have to say, we're going to look at this entire thing and we're going to take sections from the whole thing because we want to make sure there's not zones in which it's become more cancerous, more aggressive in those areas. So this lesion probably started off as a benign lyomyoma. So I think in some areas it doesn't look very atypical. Right there, that's pretty typical appearing lyomyoma. Other areas though, you see there's zones of pleomorphism and some spindle-shaped cells that are quite very",
"corrected_text": " and then it becomes much more aggressive. So that's why I'm going to do them with soft tissue. You have to think more of geography. You have to say, we're going to look at this entire thing and we're going to take sections from the whole thing because we want to make sure there's not zones in which it's become more cancerous, more aggressive in those areas. So this lesion probably started off as a benign leiomyoma. So I think in some areas it doesn't look very atypical. Right there, that's pretty typical appearing lyomyoma. Other areas though, you see there's zones of pleomorphism and some spindle cells that are quite very",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'aggressive', 'concept_id': 'C0001807', 'confidence': 1.0}, {'entity': 'soft tissue', 'concept_id': 'C0225317', 'confidence': 0.9999999403953552}], [{'entity': 'Sections', 'concept_id': 'C0007876', 'confidence': 0.8770228624343872}, {'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'zones', 'concept_id': 'C1710706', 'confidence': 0.8182461857795715}, {'entity': 'cancerous', 'concept_id': 'C1514391', 'confidence': 0.763753354549408}, {'entity': 'aggressive', 'concept_id': 'C0001807', 'confidence': 1.0}], [{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'benign leiomyoma', 'concept_id': 'C0023267', 'confidence': 0.9082092046737671}], [{'entity': 'zones', 'concept_id': 'C1710706', 'confidence': 0.8182461857795715}, {'entity': 'pleomorphism', 'concept_id': 'C0032219', 'confidence': 1.0}, {'entity': 'spindle cells', 'concept_id': 'C0682540', 'confidence': 1.0}, {'entity': 'areas', 'concept_id': 'C0205146', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_961",
"caption_rating": "7"
},
{
"": "1004807",
"caption": "Presence of collagen balls surrounded by spindle-shaped cells.",
"image_path": "8S4LeiO6Bbk_image_da91943b-95f1-427f-85ac-c15b9d31eae8.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['collagen balls', 'spindle-shaped cells', 'lipophagic cells', 'ringed siderophages', 'pigmented histiocytes', 'collagen balls', 'spindle-shaped cells', 'lipophagic cells', 'ringed siderophages', 'pigmented histiocytes']",
"noisy_text": " these collagen balls that are being surrounded by cells that have a somewhat spindled shape. The nuclei are spindled over our fusiform and they're kind of wrapping around these collagen bundles. In this same area, we can begin to see some lipophagia. So we see these large histiocytes containing lipid. Some of them are multi-nucleated and some of these are actually ringed siderophages. So we see large multi-nucleated histiocytes with a ring of nuclei and they contain not only lipid vacuoles but hemocentaurant. And these are particularly common in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes",
"corrected_text": " these collagen balls that are being surrounded by cells that have a somewhat spindle-shaped. The nuclei are spindle-shaped over our fusiform and they're kind of wrapping around these collagen bundles. In this same area, we can begin to see some lipophagic. So we see these large histiocytes containing lipid. Some of them are multi-nucleated and some of these are actually ringed siderophages. So we see large multinucleated histiocytes with a ring of nuclei and they contain not only lipid vacuoles but hemosiderin. And these are particularly common in this particular lesion that we're looking at. Moving towards the more cellular areas, we do see that we've got a lot of pigmented histiocytes here. The pigment present within these histiocytes",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'collagen balls', 'concept_id': 'C0009325', 'confidence': 0.7217866778373718}, {'entity': 'surrounded', 'concept_id': 'C1282914', 'confidence': 1.0}, {'entity': 'spindle-shaped cells', 'concept_id': 'C4230397', 'confidence': 0.803756058216095}], [{'entity': 'Lipophagic cells', 'concept_id': 'C0007584', 'confidence': 0.5962335467338562}, {'entity': 'lipid vacuoles', 'concept_id': 'C1179126', 'confidence': 1.0}, {'entity': 'hemocyanin', 'concept_id': 'C0018999', 'confidence': 0.9999998807907104}, {'entity': 'ringed', 'concept_id': 'C0325501', 'confidence': 0.77345871925354}, {'entity': 'siderophages', 'concept_id': 'C1136253', 'confidence': 0.7251443266868591}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'pigmented', 'concept_id': 'C0333610', 'confidence': 0.9999999403953552}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_962",
"caption_rating": "8"
},
{
"": "1005957",
"caption": "Intravascular neoplasm is suspected, possibly a metastatic neoplasm to the skin that is epithelial in nature.",
"image_path": "LlPaENuqzVQ_image_7b28124b-26e5-41df-a292-b4158529706a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['Atypical cells inside blood vessels with hyperchromatic nuclei.', 'Large cells hugging each other and looking epithelial.']",
"noisy_text": " So the inflammation is probably happening secondary to that. This is, whoa, these cells don't belong here. And, you know, they're sitting inside these blood vessels and they look atypical. There's like hyperchromatic nuclei here. They vary in size and shape. Like intravascular, it doesn't, like lymphoma? I mean, the only thing I think of where it's like, you don't have a huge inflammatory response like intravascular lymphoma. Yeah, yeah. So you say the intravascular neoplasm of some sort. Well, I'm not sure what this is. And they kind of look epithelial. If you look at it, it looks like these cells are really hugging one another and they're pretty large. So yeah, I would agree with you. I'd say this is an intravascular neoplasm and maybe it's a metastatic neoplasm to the skin that's possibly epithelial. If it's a lymphoma, it's going to be pretty weird. It'd have to be some kind of a histiocytoid lymphoma, something that's got these cells very large and looks like histiocytes. This is an example of an intravascular metastatic breast cancer in this case. And probably the lymphocytic infiltrator is just, you know, it's like",
"corrected_text": " So the inflammation is probably happening secondary to that. This is, whoa, these cells don't belong here. And, you know, they're sitting inside these blood vessels and they look atypical. There's like hyperchromatic nuclei here. They vary in size and shape. Like intravascular, it doesn't, like lymphoma? I mean, the only thing I think of where it's like, you don't have a huge inflammatory response like intravascular lymphoma. Yeah, yeah. So you say the intravascular neoplasm of some sort. Well, I'm not sure what this is. And they kind of look epithelial. If you look at it, it looks like these cells are really hugging one another and they're pretty large. So yeah, I would agree with you. I'd say this is an intravascular neoplasm and maybe it's a metastatic neoplasm to the skin that's possibly epithelial. If it's a lymphoma, it's going to be pretty weird. It'd have to be some kind of a histiocytic lymphoma, something that's got these cells very large and looks like histiocytes. This is an example of an intravascular metastatic breast cancer in this case. And probably the lymphocytic infiltrator is just, you know, it's like",
"med_umls_ids": "[[{'entity': 'Inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}, {'entity': 'secondary', 'concept_id': 'C0027627', 'confidence': 1.0}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'atypical cells', 'concept_id': 'C0333865', 'confidence': 1.0}, {'entity': 'blood vessels', 'concept_id': 'C0005847', 'confidence': 1.0}], [{'entity': 'Hyperchromatic nuclei', 'concept_id': 'C3553776', 'confidence': 1.0}, {'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'shape', 'concept_id': 'C0332479', 'confidence': 1.0}], [{'entity': 'Intravascular neoplasm', 'concept_id': 'C0027668', 'confidence': 0.8177628517150879}, {'entity': 'suspected', 'concept_id': 'C0332147', 'confidence': 1.0}, {'entity': 'metastatic neoplasm', 'concept_id': 'C0027627', 'confidence': 0.9999999403953552}, {'entity': 'skin', 'concept_id': 'C0444099', 'confidence': 1.0}, {'entity': 'epithelial', 'concept_id': 'C0221908', 'confidence': 1.0}, {'entity': 'nature', 'concept_id': 'C0349590', 'confidence': 1.0}], [{'entity': 'lymphoma', 'concept_id': 'C0024299', 'confidence': 1.0}, {'entity': 'histiocytic lymphoma', 'concept_id': 'C0024302', 'confidence': 1.0}, {'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'histiocytes', 'concept_id': 'C0019612', 'confidence': 1.0}], [{'entity': 'intravascular metastatic breast cancer', 'concept_id': 'C0278488', 'confidence': 0.766404926776886}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_963",
"caption_rating": "8"
},
{
"": "1009454",
"caption": "The tumor has a unique pattern of hyalinizing spindle cell tumor with giant rosettes, but the diagnosis is still low-grade fibromyxoid sarcoma.",
"image_path": "QDb68_G1HR4_image_c225f0f2-ac45-4685-aa17-97910ae9fdc4.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " So this tumor has been in the past described as hyalinizing spindle cell tumor with giant rosettes and we now recognize and have immunohistochemical and molecular proof that this is just a morphologic variation of low-grade fibromyxoid sarcoma so I'll still mention this oftentimes in the report just as a kind of a comment that this tumor has the unique pattern of hyalinizing spindle cell tumor with giant rosettes but in my line diagnosis I would still call this low-grade fibromyxoid sarcoma because it is low-grade fibromyxoid and look again how dense the collagen is in this area this is that sclerotic kind of area really has almost like a tiger",
"corrected_text": " So this tumor has been in the past described as hyalinizing spindle cell tumor with giant rosettes and we now recognize and have immunohistochemical and molecular proof that this is just a morphologic variation of low-grade fibromyxoid sarcoma so I'll still mention this oftentimes in the report just as a kind of a comment that this tumor has the unique pattern of hyalinizing spindle cell tumor with giant rosettes but in my line diagnosis I would still call this low-grade fibromyxoid sarcoma because it is low-grade fibromyxoid and look again how dense the collagen is in this area this is that sclerotic kind of area really has almost like a tiger",
"med_umls_ids": "[[{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'hyalinizing', 'concept_id': 'C0332230', 'confidence': 1.0}, {'entity': 'giant', 'concept_id': 'C0017547', 'confidence': 1.0}, {'entity': 'rosettes', 'concept_id': 'C0035863', 'confidence': 0.8847858905792236}], [{'entity': 'morphologic', 'concept_id': 'C0543482', 'confidence': 0.9229367971420288}, {'entity': 'variation', 'concept_id': 'C0205419', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}], [{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'unique', 'concept_id': 'C1710548', 'confidence': 1.0}, {'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}, {'entity': 'hyalinizing', 'concept_id': 'C0332230', 'confidence': 1.0}, {'entity': 'giant', 'concept_id': 'C0017547', 'confidence': 1.0}, {'entity': 'rosettes', 'concept_id': 'C0035863', 'confidence': 0.8847858905792236}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_964",
"caption_rating": "9"
},
{
"": "1005037",
"caption": "A tumor is colonizing and destroying previously benign glands, likely arising from the prostatic urethra.",
"image_path": "iklRyY1nBIE_image_04cd57c4-7aac-4e75-8e6f-28cd9419e459.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['tumor', 'prostatic urethra', 'inflammatory response']",
"noisy_text": " is colonizing and destroying previously benign glands. And when you see that, it's usually, obviously, you want to exclude an introductory process, colonizing benign glands. But you also want to exclude secondary tumors. Secondary tumors do that, too. Colorectal carcinoma can do that. Urethelial carcinoma can do that. But this specular entity is arising not from the colon, even though it looks like it in areas. It's also not arising from the bladder. This is actually arising from the prostatic urethra. So this is what used to be the prostatic urethra, which has been destroyed by this tumor, because the tumor actually arose from here. I'll show you some early stages of this, early forms of this. This is like an advanced case. You can see there's a very florid host inflammatory response. As you'll",
"corrected_text": " is colonizing and destroying previously benign glands. And when you see that, it's usually, obviously, you want to exclude an introductory process, colonizing benign glands. But you also want to exclude secondary tumors. Secondary tumors do that, too. Colorectal carcinoma can do that. urothelial carcinoma can do that. But this specific entity is arising not from the colon, even though it looks like it in areas. It's also not arising from the bladder. This is actually arising from the prostatic urethra. So this is what used to be the prostatic urethra, which has been destroyed by this tumor, because the tumor actually arose from here. I'll show you some early stages of this, early forms of this. This is like an advanced case. You can see there's a very florid host inflammatory response. As you'll",
"med_umls_ids": "[[{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'colonizing', 'concept_id': 'C1300196', 'confidence': 0.61208176612854}, {'entity': 'destroying', 'concept_id': 'C1948029', 'confidence': 1.0}, {'entity': 'benign glands', 'concept_id': 'C1301287', 'confidence': 0.726940393447876}, {'entity': 'prostatic urethra', 'concept_id': 'C0458450', 'confidence': 1.0}], [{'entity': 'Secondary tumors', 'concept_id': 'C0027627', 'confidence': 0.9999999403953552}, {'entity': 'colorectal carcinoma', 'concept_id': 'C0009402', 'confidence': 0.9999998807907104}, {'entity': 'urothelial carcinoma', 'concept_id': 'C0007138', 'confidence': 1.0}, {'entity': 'destroy', 'concept_id': 'C0681205', 'confidence': 0.9999999403953552}, {'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}], [{'entity': 'host', 'concept_id': 'C1167395', 'confidence': 0.9999999403953552}, {'entity': 'inflammatory response', 'concept_id': 'C1155266', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_965",
"caption_rating": "8"
},
{
"": "1009159",
"caption": "Superficial injury with relatively preserved bottom crypts is indicative of ischemia.",
"image_path": "sDFjOtMAYrk_image_58a2cf0e-9b77-4366-a034-6aa08c3f4e31.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['Superficial injury', 'Bottom crypts', 'Hyalinized lamina propria', 'Cytologic atypia', 'Superficial injury', 'Bottom crypts', 'Hyalinized lamina propria', 'Cytologic atypia']",
"noisy_text": " what you see in patients with ischemia. So basically, injury that's predominantly superficial with relative preservation of the bottom crypts. Very hyaluronized lamina propria when the ischemia has been ongoing for a while. It may or may not be there when the ischemia has been short-lived. Here you can see very nicely the superficial injury with relatively preserved bottoms. I find the cytologic atypia really helpful when I'm dealing with cases where I really don't know what's going on. I've caught maybe one or two cases of patients with subclinical very mild level ischemia that the only finding was just the cytologic atypia that I don't know where it's really coming from. And I'll show a case down the road. Actually, I'll show it right now. So this is a patient who I don't really remember the clinical history. I just thought, I mean, the architecture",
"corrected_text": " what you see in patients with ischemia. So basically, injury that's predominantly superficial with relative preservation of the bottom crypts. Very hyalinized lamina propria when the ischemia has been ongoing for a while. It may or may not be there when the ischemia has been short-lived. Here you can see very nicely the superficial injury with relatively preserved bottoms. I find the cytologic atypia really helpful when I'm dealing with cases where I really don't know what's going on. I've caught maybe one or two cases of patients with subclinical very mild level ischemia that the only finding was just the cytologic atypia that I don't know where it's really coming from. And I'll show a case down the road. Actually, I'll show it right now. So this is a patient who I don't really remember the clinical history. I just thought, I mean, the architecture",
"med_umls_ids": "[[{'entity': 'Superficial injury', 'concept_id': 'C0332671', 'confidence': 1.0}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}], [{'entity': 'Hyalinized lamina propria', 'concept_id': 'C0332230', 'confidence': 0.7577076554298401}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}], [{'entity': 'Cytologic atypia', 'concept_id': 'C0333865', 'confidence': 1.0}, {'entity': 'finding', 'concept_id': 'C0037088', 'confidence': 1.0}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'mild', 'concept_id': 'C1513302', 'confidence': 1.0}, {'entity': 'ischemia', 'concept_id': 'C0022116', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_966",
"caption_rating": "8"
},
{
"": "1007164",
"caption": "The collagen fibers are wavy, indicating a fibroblastic proliferation rather than a neural proliferation.",
"image_path": "QDb68_G1HR4_image_456bb1de-691c-4dfb-a9c1-ac6fbf8892e0.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['wavy collagen fibers', 'fibroblastic proliferation', 'neural proliferation', 'wavy collagen fibers', 'fibroblastic proliferation', 'neural proliferation']",
"noisy_text": " and you can see that the actual collagen fibers are really wavy up and down that usually is a sign that you're dealing with a fibroblastic proliferation not a neural proliferation. Neural proliferations are gently wavy gently undulating and usually not strikingly wavy like this my fellow Ed Fulton my DermPath fellow from from last year he loves to say he told me that he thought to the collagen here looks kind of like ramen noodles the dry ramen noodles when they first come out of the package if you don't know what that looks like you should a buy some ramen noodles and eat them because they're good and also you should go do a Google image search and you can see what ramen noodles in a package look like",
"corrected_text": " and you can see that the actual collagen fibers are really wavy up and down that usually is a sign that you're dealing with a fibroblastic proliferation not a neural proliferation. Neural proliferations are gently wavy gently undulating and usually not strikingly wavy like this my fellow Ed Fulton my DermPath fellow from from last year he loves to say he told me that he thought to the collagen here looks kind of like ramen noodles the dry ramen noodles when they first come out of the package if you don't know what that looks like you should a buy some ramen noodles and eat them because they're good and also you should go do a Google image search and you can see what ramen noodles in a package look like",
"med_umls_ids": "[[{'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'fibers', 'concept_id': 'C0000696', 'confidence': 0.9201323986053467}, {'entity': 'wavy', 'concept_id': 'C1969185', 'confidence': 0.8467161655426025}, {'entity': 'fibroblastic proliferation', 'concept_id': 'C1326347', 'confidence': 0.9352954626083374}, {'entity': 'neural proliferation', 'concept_id': 'C0334094', 'confidence': 0.8048738241195679}], [{'entity': 'Neural proliferations', 'concept_id': 'C0334094', 'confidence': 0.826797604560852}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_967",
"caption_rating": "9"
},
{
"": "1008982",
"caption": "Tuberculoid form of leprosy can cause sarcoid granulomatous inflammation.",
"image_path": "udoW6VSqsm4_image_f8689d95-7530-4b83-898a-d4cd00fc356d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['sarcoid granulomatous inflammation', 'involvement around nerves', 'sarcoid granulomatous inflammation', 'involvement around nerves']",
"noisy_text": " That's the tuberculoid. Yeah, good. The tuberculoid form of leprosy gives you sarcoidal granulomatous inflammation. It's elongated. Very good. That's exactly right. What else can give you sarcoidal granulomatous inflammation? Can I ask a quick question about the sarcoid with the two... The nansins? So, I had a case, I saw a case that looked kind of horizontal, but it was sarcoid. And so, what other ways can you tell? Sometimes it can be difficult, but usually you're going to see involvement around nerves damaged nerves. You're about to get sarcoidal granulomatous inflammation. They always have very high risk inflammatory reactions. They just wipe out the nerves. So, that's helpful. Wasn't",
"corrected_text": " That's the tuberculoid. Yeah, good. The tuberculoid form of leprosy gives you sarcoidal granulomatous inflammation. It's elongated. Very good. That's exactly right. What else can give you sarcoidal granulomatous inflammation? Can I ask a quick question about the sarcoid with the two... The sarcoidosis? So, I had a case, I saw a case that looked kind of horizontal, but it was sarcoid. And so, what other ways can you tell? Sometimes it can be difficult, but usually you're going to see involvement around nerves damaged nerves. You're about to get sarcoidal granulomatous inflammation. They always have very high risk inflammatory reactions. They just wipe out the nerves. So, that's helpful. Wasn't",
"med_umls_ids": "[[{'entity': 'Tuberculoid', 'concept_id': 'C0544783', 'confidence': 0.8459237217903137}, {'entity': 'leprosy', 'concept_id': 'C0023343', 'confidence': 1.0}, {'entity': 'sarcoid', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'granulomatous inflammation', 'concept_id': 'C0553697', 'confidence': 1.0}], [{'entity': 'Involvement', 'concept_id': 'C1314939', 'confidence': 1.0}, {'entity': 'damaged nerves', 'concept_id': 'C3887709', 'confidence': 0.8087002038955688}, {'entity': 'sarcoid', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'granulomatous inflammation', 'concept_id': 'C0553697', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_968",
"caption_rating": "7"
},
{
"": "1005179",
"caption": "Muscularization of the lamina propria in gastric mucosa may indicate chemical gastritis, which can be caused by biliary reflux or NSAID use.",
"image_path": "r7OA0Trj5hQ_image_ddce5612-5ad7-4516-a2fe-15aa78808396.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['muscularization of the lamina propria', 'gastric mucosa', 'chemical gastritis', 'antral biopsy', 'inflammation', 'muscularization of the lamina propria', 'gastric mucosa', 'chemical gastritis', 'antral biopsy', 'inflammation']",
"noisy_text": " and in cases of mucosal prolapse in colon. Remember that solitary rectal ulcer syndrome, which is totally misnomer. It is neither solitary, can be seen in other parts other than rectum. There may not be any ulcer, there is no syndrome. So the whole solitary rectal ulcer syndrome is a misnomer. But muscularization of the lamina propria is one of the criteria for mucosal prolapse that is happening in solitary rectal ulcer syndrome. And this is a gastric mucosa. Here when you see muscularization of the lamina propria, you have to think of chemical gastritis. Will it form surface changes? Lamina propria edema and muscularis mucosa coming into the lamina propria. These are the three criterias. When you see it in the anterobiopsy, think of chemical gastritis that can be seen in biliary reflux or NSAID use. Lot of inflammation results. Remember I",
"corrected_text": " and in cases of mucosal prolapse in colon. Remember that solitary rectal ulcer syndrome, which is totally misnomer. It is neither solitary, can be seen in other parts other than rectum. There may not be any ulcer, there is no syndrome. So the whole solitary rectal ulcer syndrome is a misnomer. But muscularization of the lamina propria is one of the criteria for mucosal prolapse that is happening in solitary rectal ulcer syndrome. And this is a gastric mucosa. Here when you see muscularization of the lamina propria, you have to think of chemical gastritis. Will it form surface changes? Lamina propria edema and muscularis mucosa coming into the lamina propria. These are the three criteria. When you see it in the endoscopic biopsy, think of chemical gastritis that can be seen in biliary reflux or NSAID use. Lot of inflammation results. Remember I",
"med_umls_ids": "[[{'entity': 'Muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'criterion', 'concept_id': 'C0243161', 'confidence': 1.0}, {'entity': 'mucosal prolapse', 'concept_id': 'C0034888', 'confidence': 0.826268196105957}, {'entity': 'colon', 'concept_id': 'C0009368', 'confidence': 1.0}, {'entity': 'solitary rectal ulcer syndrome', 'concept_id': 'C4274343', 'confidence': 0.9999999403953552}], [{'entity': 'Muscularization', 'concept_id': 'C0027686', 'confidence': 0.7611830234527588}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'gastric mucosa', 'concept_id': 'C0017136', 'confidence': 1.0}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}, {'entity': 'biliary reflux', 'concept_id': 'C0232483', 'confidence': 0.7931289672851562}, {'entity': 'NSAID', 'concept_id': 'C0003211', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_969",
"caption_rating": "9"
},
{
"": "1004201",
"caption": "The presence of a ring chromosome and translocation involving collagen A and platelet-derived growth factor is classic for DFSP.",
"image_path": "LlPaENuqzVQ_image_76a5b714-55f4-4548-a00f-fcd28a02bf2a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['diffuse pattern between and among lipocytes', 'typical storiform pattern', 'ring chromosome', 'translocation involving collagen A and platelet-derived growth factor', 'diffuse pattern between and among lipocytes']",
"noisy_text": " you can impress your friends and colleagues. You can say, this is DFSB. You don't need the storiform pattern. If you see this, you got the diagnosis. No other neoplasm really gets diffusely between and among lipocytes in a diffuse pattern like this, other than DFSB. Now you look up here and yeah, you do have the nice, beautiful storiform pattern here. And you don't really need a CD34 stain here. You can do it if you want to, if you like to sort of charge patients extra money, but this is a classic DFSB. And that ring chromosome, the collagen A, platelet-derived growth factor, the translocation is classic for that. And one",
"corrected_text": " you can impress your friends and colleagues. You can say, this is DFSP. You don't need the storiform pattern. If you see this, you got the diagnosis. No other neoplasm really gets diffusely between and among lipocytes in a diffuse pattern like this, other than DFSP. Now you look up here and yeah, you do have the nice, typical storiform pattern here. And you don't really need a CD34 stain here. You can do it if you want to, if you like to sort of charge patients extra money, but this is a classic DFSP. And that ring chromosome, the collagen A, platelet-derived growth factor, the translocation is classic for that. And one",
"med_umls_ids": "[[{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'diffuse', 'concept_id': 'C0205219', 'confidence': 1.0}, {'entity': 'lipocytes', 'concept_id': 'C0206131', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}], [{'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}, {'entity': 'storiform pattern', 'concept_id': 'C1336510', 'confidence': 0.8142904043197632}], [{'entity': 'CD34 stain', 'concept_id': 'C0038128', 'confidence': 0.5134490728378296}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'ring chromosome', 'concept_id': 'C0035639', 'confidence': 1.0}, {'entity': 'translocation', 'concept_id': 'C0040715', 'confidence': 1.0}, {'entity': 'collagen A', 'concept_id': 'C0009325', 'confidence': 0.9128584265708923}, {'entity': 'platelet-derived growth factor', 'concept_id': 'C0032200', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_970",
"caption_rating": "9"
},
{
"": "1004843",
"caption": "Punch biopsy showing an interface dermatitis on the trunk.",
"image_path": "8S4LeiO6Bbk_image_9ce3c52a-4c31-4758-b5c6-6541c12d3d6e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Biopsy specimen from the trunk.']",
"noisy_text": " Okay, let's go ahead and move on to slide number nine. This was another example of an interface dermatitis. We have a bisected punch biopsy here. This biopsy specimen was from the trunk and one can see that we've got a superficial and deep perivascular infiltrate present in these sections as a vague wedge-shaped configuration. If we look at the epidermis, we can see, again, there's an obscuration of the normal epidermal junction by bacular change and Apache lymphocytic infiltrate. In this particular instance, there's also a little bit of spongiosis with exocytosis of lymphocytes into widened intracellular spaces, and there are some mounds of perikaratosis within the",
"corrected_text": " Okay, let's go ahead and move on to slide number nine. This was another example of an interface dermatitis. We have a bisected punch biopsy here. This biopsy specimen was from the trunk and one can see that we've got a superficial and deep perivascular infiltrate present in these sections as a vague wedge-shaped configuration. If we look at the epidermis, we can see, again, there's an obscuration of the normal epidermal junction by vacuolar change and Apache lymphocytic infiltrate. In this particular instance, there's also a little bit of spongiosis with exocytosis of lymphocytes into widened intracellular spaces, and there are some mounds of parakeratosis within the",
"med_umls_ids": "[[{'entity': 'Punch biopsy', 'concept_id': 'C0182557', 'confidence': 1.0}, {'entity': 'interface dermatitis', 'concept_id': 'C0262981', 'confidence': 1.0}, {'entity': 'trunk', 'concept_id': 'C0225442', 'confidence': 0.9999999403953552}], [{'entity': 'Superficial', 'concept_id': 'C0205124', 'confidence': 1.0}, {'entity': 'deep perivascular infiltrate', 'concept_id': 'C4531289', 'confidence': 0.8486854434013367}, {'entity': 'sections', 'concept_id': 'C0007876', 'confidence': 0.8770228624343872}, {'entity': 'wedge-shaped configuration', 'concept_id': 'C1695776', 'confidence': 0.6548662185668945}], [{'entity': 'Obscuration', 'concept_id': 'C4100897', 'confidence': 0.8260445594787598}, {'entity': 'vacuolar change', 'concept_id': 'C0010840', 'confidence': 1.0}, {'entity': 'Apache lymphocytic infiltrate', 'concept_id': 'C0333386', 'confidence': 0.8769314885139465}], [{'entity': 'Spongiosis', 'concept_id': 'C0702120', 'confidence': 1.0}, {'entity': 'exocytosis', 'concept_id': 'C0015283', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'intracellular', 'concept_id': 'C0175996', 'confidence': 1.0}, {'entity': 'spaces', 'concept_id': 'C1883067', 'confidence': 0.7782474160194397}, {'entity': 'mounds', 'concept_id': 'C2717795', 'confidence': 0.736616313457489}, {'entity': 'parakeratosis', 'concept_id': 'C0030436', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_971",
"caption_rating": "8"
},
{
"": "1004343",
"caption": "This constellation of features is very characteristic of a variant of porokeratosis that tends to produce papules and at times very large.",
"image_path": "8S4LeiO6Bbk_image_9ceb5416-9bcf-4224-85d1-aca7eb1a5922.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['Vertical column of parakeratosis with underlying dyskeratotic cells in the stratum corneum and an absent granule layer (cornoid lamella)', 'Vertical column of parakeratosis with underlying dyskeratotic cells in the stratum corneum and an absent granule layer (cornoid lamella)']",
"noisy_text": " cells and also if we look in the dermal papillae between these zones, there are really no identifiable foam cells present within the dermal papillae. Looking over at the far edge of this lesion however, we can see that we've got this vertical column of pericaratosis with underlying dyskeratotic cells in the stratum corneum and an absent granule layer and this is very characteristic and meets all the criteria for a cornoid lamella. So we have this hyperplastic epidermis that is papillated with an inflammatory infiltrate and several discrete cornoid lamella formation across the biopsy specimen and this constellation of features is very characteristic of a variant of porocaratosis that tends to produce papules and at times very large plaques in",
"corrected_text": " cells and also if we look in the papillary dermis between these zones, there are really no identifiable foam cells present within the papillary dermis. Looking over at the far edge of this lesion however, we can see that we've got this vertical column of parakeratosis with underlying dyskeratotic cells in the stratum corneum and an absent granule layer and this is very characteristic and meets all the criteria for a cornoid lamella. So we have this hyperplastic epidermis that is papillary with an inflammatory infiltrate and several discrete cornoid lamella formation across the biopsy specimen and this constellation of features is very characteristic of a variant of porokeratosis that tends to produce papules and at times very large plaques in",
"med_umls_ids": "[[{'entity': 'biopsy specimen', 'concept_id': 'C0677862', 'confidence': 1.0}, {'entity': 'hyperplastic epidermis', 'concept_id': 'C4748317', 'confidence': 0.7633129358291626}, {'entity': 'papillary', 'concept_id': 'C0205312', 'confidence': 1.0}, {'entity': 'inflammatory infiltrate', 'concept_id': 'C3887644', 'confidence': 0.9999999403953552}, {'entity': 'discrete cornoid lamella formation', 'concept_id': 'C3552548', 'confidence': 0.7204381823539734}], [{'entity': 'constellation', 'concept_id': 'C5227392', 'confidence': 0.6721397042274475}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'variant', 'concept_id': 'C0205419', 'confidence': 1.0}, {'entity': 'porokeratosis', 'concept_id': 'C0162839', 'confidence': 1.0}, {'entity': 'papules', 'concept_id': 'C0332563', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_972",
"caption_rating": "8"
},
{
"": "1006213",
"caption": "The lesion in question is a hemosiderotic or aneurysmal type of dermatofibroma, also known as a sclerosing hemangioma variant of a dermatofibroma.",
"image_path": "8S4LeiO6Bbk_image_bb553ad9-91c5-4867-9261-6ce8b5efcff2.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['fascicles of histiocytes and fibrocytes with oval and fusiform nuclei']",
"noisy_text": " the to the lesion in question, we've got a lot of hemocentaurant-laden histiocytes here. We've also got, in other areas, fascicles, kind of randomly oriented of histiocytes and fibrocytes with oval and fusiform nuclei. There's a little bit of nuclear pleomorphism, but if you know, we're not seeing any necrosis or an appreciable number of mitotic figures. And this large cellular fibrohystic-acidic infiltrate, again with the collagen trapping and ring siderophages out of the periphery, seems to be compressing the fat. And the constellation of features in these sections is pathognomonic, of course, or a hemociderotic or aneurysmal type of dermatofibroma, also known as a sclerosing hemangioma variant of a dermatofibroma. This is a type of",
"corrected_text": " the to the lesion in question, we've got a lot of hemocentaurant-laden histiocytes here. We've also got, in other areas, fascicles, kind of randomly oriented of histiocytes and fibrocytes with oval and fusiform nuclei. There's a little bit of nuclear pleomorphism, but if you know, we're not seeing any necrosis or an appreciable number of mitotic figures. And this large cellular fibrohystic-acidic infiltrate, again with the collagen trapping and ring siderophages out of the periphery, seems to be compressing the fat. And the constellation of features in these sections is pathognomonic, of course, or a hemosiderotic or aneurysmal type of dermatofibroma, also known as a sclerosing hemangioma variant of a dermatofibroma. This is a type of",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'question', 'concept_id': 'C1522634', 'confidence': 1.0}, {'entity': 'hemosiderotic', 'concept_id': 'C0019114', 'confidence': 0.7758374810218811}, {'entity': 'aneurysmal type', 'concept_id': 'C0439651', 'confidence': 0.8459930419921875}, {'entity': 'dermatofibroma', 'concept_id': 'C0002991', 'confidence': 1.0}, {'entity': 'sclerosing', 'concept_id': 'C0036426', 'confidence': 0.833010733127594}, {'entity': 'hemangioma', 'concept_id': 'C0018916', 'confidence': 1.0}, {'entity': 'variant', 'concept_id': 'C0205419', 'confidence': 1.0}, {'entity': 'dermatofibroma', 'concept_id': 'C0002991', 'confidence': 1.0}], [{'entity': 'sections', 'concept_id': 'C0007876', 'confidence': 0.8770228624343872}, {'entity': 'cellular fibrohistiocytic infiltrate', 'concept_id': 'C0019618', 'confidence': 0.7253735065460205}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'trapping', 'concept_id': 'C0282665', 'confidence': 0.8904784917831421}, {'entity': 'ring siderophages', 'concept_id': 'C1136253', 'confidence': 0.6553963422775269}], [{'entity': 'nuclear pleomorphism', 'concept_id': 'C1518437', 'confidence': 1.0}, {'entity': 'necrosis', 'concept_id': 'C0027540', 'confidence': 1.0}, {'entity': 'mitoses', 'concept_id': 'C0026255', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "758.0",
"width": "1920.0",
"id": "test_973",
"caption_rating": "9"
},
{
"": "1007110",
"caption": "The patient had a history of uveitis with characteristic features of sarcoidosis.",
"image_path": "sDFjOtMAYrk_image_bd78a499-7df9-4eaa-9442-5bfa70ba065e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['granuloma', 'granuloma', 'lamina propria', 'Crohn\u2019s disease', 'infectious process', 'sarcoidosis', 'uveitis']",
"noisy_text": " I like this place. So if you have big coalescing masses of granuloma, expanding your lamina propria, think something other than Crohn's. Think of infectious process, especially if they're necrotizing, but even if they're not, and also think of sarcoid. This patient had sarcoid. So I said, this is probably not IBD, clinicians came down, we want to look at the biopsy, of course. It turns out that they went back and talked to the patient. The patient has a history of uveitis with characteristic features that were good for sarcoidosis. Nobody knew about they treated the patient for sarcoid, re-biopsied the patient. And he was fine. There were no more granulomas on multiple repeat biopsies. And now compare those grannies with the grannies in Crohn's. So here's",
"corrected_text": " I like this place. So if you have big coalescing masses of granuloma, expanding your lamina propria, think something other than Crohn's. Think of infectious process, especially if they're necrotizing, but even if they're not, and also think of sarcoid. This patient had sarcoid. So I said, this is probably not IBD, clinicians came down, we want to look at the biopsy, of course. It turns out that they went back and talked to the patient. The patient has a history of uveitis with characteristic features that were good for sarcoidosis. Nobody knew about they treated the patient for sarcoid, re-biopsied the patient. And he was fine. There were no more granulomas on multiple repeat biopsies. And now compare those grannies with the grannies in Crohn's. So here's",
"med_umls_ids": "[[{'entity': 'Coalescing masses', 'concept_id': 'C4727092', 'confidence': 0.5960795283317566}, {'entity': 'granuloma', 'concept_id': 'C0018188', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'infectious process', 'concept_id': 'C0745283', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'Crohn\u2019s disease', 'concept_id': 'C0010346', 'confidence': 0.8916962146759033}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'history', 'concept_id': 'C0019664', 'confidence': 1.0}, {'entity': 'uveitis', 'concept_id': 'C0042164', 'confidence': 1.0}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}], [{'entity': 'Re-biopsy', 'concept_id': 'C0005558', 'confidence': 0.6681398749351501}, {'entity': 'granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}, {'entity': 'treatment', 'concept_id': 'C0039798', 'confidence': 1.0}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_974",
"caption_rating": "8"
},
{
"": "1005294",
"caption": "Sarcoidosis can have various clinical manifestations, including the deeper nodular form, the Dariae ruse type.",
"image_path": "udoW6VSqsm4_image_21d07b99-d98c-471e-abc9-857c7318fe6e.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['Lesions around the A-web, the nose', 'Deeper nodular form of sarcoidosis']",
"noisy_text": " So, yeah, there's several other things you can do. We're doing ulcerative colitis with rosacea sometimes. Usually not this intense, but you can see it in rosacea also. So, we'll show the picture of this. So, this is a classic clinical. These are lesions around the A-web, the nose. Beautiful example. The deeper nodular form, the Dariae ruse type of sarcoid. The guy on the right is going to come over and plaque wipe the area. So, there are a lot of clinical manifestations of sarcoidosis. So, yeah, this is a beautiful example of that. Caneous Crohn's, that's why I was going to ask. Caneous Crohn's can look sort of like this, yeah. That would be the differential also. So, yeah, you think about that. Usually, you know, Balfour's and Rosenthal. Usually not quite this degree like you see here. This is really a great example of real sarcoid. But, obviously,",
"corrected_text": " So, yeah, there's several other things you can do. We're doing ulcerative colitis with rosacea sometimes. Usually not this intense, but you can see it in rosacea also. So, we'll show the picture of this. So, this is a classic clinical. These are lesions around the A-web, the nose. Beautiful example. The deeper nodular form, the Dariae ruse type of sarcoid. The guy on the right is going to come over and plaque wipe the area. So, there are a lot of clinical manifestations of sarcoidosis. So, yeah, this is a beautiful example of that. cutaneous Crohn's, that's why I was going to ask. cutaneous Crohn's can look sort of like this, yeah. That would be the differential also. So, yeah, you think about that. Usually, you know, Balfour's and Rosenthal. Usually not quite this degree like you see here. This is really a great example of sarcoidosis. But, obviously,",
"med_umls_ids": "[[{'entity': 'Ulcerative colitis', 'concept_id': 'C0009324', 'confidence': 1.0}, {'entity': 'rosacea', 'concept_id': 'C0035854', 'confidence': 1.0}, {'entity': 'lesions', 'concept_id': 'C0221198', 'confidence': 1.0}, {'entity': 'A-web', 'concept_id': 'C0282111', 'confidence': 0.5314000844955444}, {'entity': 'nose', 'concept_id': 'C0028429', 'confidence': 0.9999999403953552}], [{'entity': 'Sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}, {'entity': 'clinical manifestations', 'concept_id': 'C4231046', 'confidence': 0.9626281261444092}, {'entity': 'nodular form', 'concept_id': 'C0205297', 'confidence': 0.8008954524993896}, {'entity': 'Dariae ruse type', 'concept_id': 'C0332307', 'confidence': 0.5478090047836304}], [{'entity': 'Cutaneous Crohns', 'concept_id': 'C0221912', 'confidence': 0.5978212356567383}, {'entity': 'clinical presentation', 'concept_id': 'C4554564', 'confidence': 0.8858868479728699}, {'entity': 'sarcoidosis', 'concept_id': 'C0036202', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_975",
"caption_rating": "7"
},
{
"": "1005509",
"caption": "Cellular DF with lipid accumulation is commonly located on the legs, particularly the ankle.",
"image_path": "udoW6VSqsm4_image_d327ce07-00c2-4757-a820-f54f96604301.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "[]",
"noisy_text": " This one is a nice example of like a cellular DF with lipidization. What part of the body are these most commonly located on? Legs? Yeah, the ankle. In fact, they used to be called the ankle type DF. People still call it that because that's their common location. I don't know why it always occurs in that location, but that's a very common site where you see these. Sometimes they can be several centimeters. If they're really big, they're still benign. Rarely there's been a case of corks and Fletcher who reports everything that can possibly happen that they need to spread to localized nodes. But anyway,",
"corrected_text": " This one is a nice example of like a cellular DF with lipidization. What part of the body are these most commonly located on? Legs? Yeah, the ankle. In fact, they used to be called the ankle type DF. People still call it that because that's their common location. I don't know why it always occurs in that location, but that's a very common site where you see these. Sometimes they can be several centimeters. If they're really big, they're still benign. Rarely there's been a case of corks and Fletcher who reports everything that can possibly happen that they need to spread to localized nodes. But anyway,",
"med_umls_ids": "[[{'entity': 'Cellular DF', 'concept_id': 'C0007634', 'confidence': 0.7029635906219482}, {'entity': 'lipid accumulation', 'concept_id': 'C0333574', 'confidence': 1.0}, {'entity': 'legs', 'concept_id': 'C1140621', 'confidence': 1.0}, {'entity': 'ankle', 'concept_id': 'C0003086', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_976",
"caption_rating": "7"
},
{
"": "1008320",
"caption": "Description of the vessel pattern seen in myxoid liposarcoma, which includes delicate vessels with single file endothelial cells and no muscle layer or pericytes.",
"image_path": "pBR26SS0FX8_image_9b09f62b-7b59-430c-9ce5-0d70de861ae3.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Hematopathology', 'Breast pathology']",
"roi_text": "['red cells in vessels resembling rollo formation', 'single file endothelial cells', 'vessel pattern in myxoid liposarcoma', 'delicate vessels that break open easily.']",
"noisy_text": " If you find ones with red cells in them, sometimes the red cells look like rollo formation. There's like only room for one single, single file endothelial cells to go through the vessel. That's the way I like to think of them. So if you're seeing vessels that are branchy, but have like a muscle layer around them, a nice layer of pericytes, obviously around the outside of the endothelium, that's not the vessel pattern that you look for in myxoid liposarcoma. You want these super delicate vessels that if you touch them, they just break open, right? Look at that.",
"corrected_text": " If you find ones with red cells in them, sometimes the red cells look like rollo formation. There's like only room for one single, single file endothelial cells to go through the vessel. That's the way I like to think of them. So if you're seeing vessels that are branching, but have like a muscle layer around them, a nice layer of pericytes, obviously around the outside of the endothelium, that's not the vessel pattern that you look for in myxoid liposarcoma. You want these super delicate vessels that if you touch them, they just break open, right? Look at that.",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'vessel', 'concept_id': 'C0005847', 'confidence': 1.0}, {'entity': 'pattern', 'concept_id': 'C0449774', 'confidence': 1.0}, {'entity': 'myxoid liposarcoma', 'concept_id': 'C0206634', 'confidence': 1.0}, {'entity': 'delicate vessels', 'concept_id': 'C0005847', 'confidence': 0.7629815936088562}, {'entity': 'endothelial cells', 'concept_id': 'C0225336', 'confidence': 1.0}, {'entity': 'muscle layer', 'concept_id': 'C0225358', 'confidence': 1.0}, {'entity': 'pericytes', 'concept_id': 'C0598800', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_977",
"caption_rating": "9"
},
{
"": "1008782",
"caption": "DFSPs can have vesicular and herringbone areas as they transform into a higher grade form.",
"image_path": "QDb68_G1HR4_image_7603fd9a-353a-483f-8a51-e8ef46508e9a.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " here like that see all the cells are kind of streaming the same direction so one thing you could consider here I think would be would be a dermata fibrosarcoma protuberans a myxoid DFSP DFSPs particularly as they transform into a higher grade form they can begin to get kind of vesicular almost herringbone areas and even though this isn't nearly as cellular as a fibrosarcoma as DFSP I think still seeing myxoid bland spindle cell thing that has that has areas like this could really make me wonder am I dealing with a DFSP and DFSPs that get more cellular",
"corrected_text": " here like that see all the cells are kind of streaming the same direction so one thing you could consider here I think would be would be a dermatofibrosarcoma protuberans a myxoid DFSP DFSPs particularly as they transform into a higher grade form they can begin to get kind of vesicular almost herringbone areas and even though this isn't nearly as cellular as a fibrosarcoma as DFSP I think still seeing myxoid bland spindle cell thing that has that has areas like this could really make me wonder am I dealing with a DFSP and DFSPs that get more cellular",
"med_umls_ids": "[[{'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'dermatofibrosarcoma protuberans', 'concept_id': 'C0206647', 'confidence': 1.0}, {'entity': 'DFSP', 'concept_id': 'C0392784', 'confidence': 1.0}, {'entity': 'streaming', 'concept_id': 'C0720356', 'confidence': 0.736393928527832}, {'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'direction', 'concept_id': 'C0449738', 'confidence': 1.0}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'myxoid bland spindle cells', 'concept_id': 'C0682540', 'confidence': 0.6821858286857605}], [{'entity': 'DFSPs', 'concept_id': 'C0334464', 'confidence': 0.8083938360214233}, {'entity': 'vesicular', 'concept_id': 'C0205378', 'confidence': 1.0}, {'entity': 'herringbone areas', 'concept_id': 'C0264075', 'confidence': 0.7204739451408386}, {'entity': 'transform', 'concept_id': 'C1510411', 'confidence': 0.8196498155593872}, {'entity': 'higher', 'concept_id': 'C0205250', 'confidence': 1.0}, {'entity': 'grade form', 'concept_id': 'C0441800', 'confidence': 0.7383699417114258}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_978",
"caption_rating": "8"
},
{
"": "1008253",
"caption": "The tissue sample is not indicative of Crohn's disease due to preserved architecture and coalescing masses of granulomas that are expanding the lamina propria.",
"image_path": "sDFjOtMAYrk_image_4c518c51-7ba0-469b-bf27-ada67608e34f.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['coalescing masses of granulomas', 'expanding the lamina propria']",
"noisy_text": " Crohn's. No. Why is it not Crohn's? So two main reasons why it's not Crohn's. So number one, the architecture is completely preserved. Okay. That can happen in Crohn's. Why not? The granulomas are too good to be true. You can have granulomas sometimes will form in Crohn's of course, rarely, but they won't be coalescing. They won't be expanding the lamina propria to this degree. So if you have coalescing masses of granulomas, quite romantic. I like this place. So if you have big coalescing masses of granuloma, expanding your lamina propria, think something other than Crohn's. Think of infectious process, especially if",
"corrected_text": " Crohn's. No. Why is it not Crohn's? So two main reasons why it's not Crohn's. So number one, the architecture is completely preserved. Okay. That can happen in Crohn's. Why not? The granulomas are too good to be true. You can have granulomas sometimes will form in Crohn's of course, rarely, but they won't be coalescing. They won't be expanding the lamina propria to this degree. So if you have coalescing masses of granulomas, quite romantic. I like this place. So if you have big coalescing masses of granuloma, expanding your lamina propria, think something other than Crohn's. Think of infectious process, especially if",
"med_umls_ids": "[[{'entity': 'tissue', 'concept_id': 'C0040300', 'confidence': 1.0}, {'entity': \"Crohn's disease\", 'concept_id': 'C0010346', 'confidence': 1.0}, {'entity': 'architecture', 'concept_id': 'C0003737', 'confidence': 1.0}, {'entity': 'coalescing masses', 'concept_id': 'C4727092', 'confidence': 0.5960795283317566}, {'entity': 'granulomas', 'concept_id': 'C0018188', 'confidence': 1.0}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}], [{'entity': 'Infectious process', 'concept_id': 'C0745283', 'confidence': 1.0}, {'entity': 'Crohn\u2019s disease', 'concept_id': 'C0010346', 'confidence': 0.8916962146759033}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_979",
"caption_rating": "8"
},
{
"": "1006806",
"caption": "A small subset of these tumors actually occur de novo within a previously benign gland.",
"image_path": "iklRyY1nBIE_image_06474144-5c48-46a7-8e65-c93b6249c886.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['basal cells at the periphery', 'enlarged nuclei', 'intraductal carcinoma of the prostate', 'adjacent invasive tumor', 'previously benign gland', 'basal cells at the periphery', 'enlarged nuclei', 'intraductal carcinoma of the prostate', 'adjacent invasive tumor', 'previously benign gland']",
"noisy_text": " Let me show you what the cocktail looks like. Again, this is the pin three, or some call it pin four. You have the P63, you have the hemoglobin cytokeratin, and then you have the racemase, which is the pink chromogen. And as you can see, as I demonstrated on the H&E, basal cells are indeed present. This is too much for high-grade pin. This is basically what is called a solid cribriform kind of pattern, in which over 50% of the lumen is filled by tumor cells. So this is way too much for high-grade pin. But it's not invasive, because you have basal cells at the periphery. And the nuclei are enlarged. These nuclei are about six times the size of normal prostate nuclei. So this case meets the criteria for introductal carcinoma of the prostate. There is an invasive component, which you can see is negative for basal cell markers. But you have the introductal component. And this is a very interesting entity. The vast majority of cases, and I'll show you the corresponding radical prostatectomy specimens in a second, but the vast majority of these so-called introductal carcinoma of the prostate is due to invasion, colonization by adjacent invasive tumor. And it usually occurs in patients that have high-volume tumors. When I show you the corresponding radical prostatectomies, you'll see what I'm talking about. You usually don't have this in patients in their radicals that have 5% prostate cancer or 10% prostate cancer. It's usually patients that have extensive prostate cancer involvement, and the invasive glands basically have nowhere else to go but to colonize adjacent benign glands. And I'll demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues,",
"corrected_text": " Let me show you what the cocktail looks like. Again, this is the pin three, or some call it pin four. You have the P63, you have the hemoglobin cytokeratin, and then you have the racemase, which is the AMACR. And as you can see, as I demonstrated on the H&E, basal cells are indeed present. This is too much for high-grade pin. This is basically what is called a solid cribriform kind of pattern, in which over 50% of the lumen is filled by tumor cells. So this is way too much for high-grade pin. But it's not invasive, because you have basal cells at the periphery. And the nuclei are enlarged. These nuclei are about six times the size of normal prostate nuclei. So this case meets the criteria for intraductal carcinoma of the prostate. There is an invasive component, which you can see is negative for basal cell markers. But you have the intraductal component. And this is a very interesting entity. The vast majority of cases, and I'll show you the corresponding radical prostatectomy specimens in a second, but the vast majority of these so-called intraductal carcinoma of the prostate is due to invasion, colonization by adjacent invasive tumor. And it usually occurs in patients that have high-volume tumors. When I show you the corresponding radical prostatectomies, you'll see what I'm talking about. You usually don't have this in patients in their radicals that have 5% prostate cancer or 10% prostate cancer. It's usually patients that have extensive prostate cancer involvement, and the invasive glands basically have nowhere else to go but to colonize adjacent benign glands. And I'demonstrate that to you shortly. But there's a small subset of these tumors that actually occur de novo, which means that they do not have adjacent invasive cancer, but arise de novo within a previously benign gland. But that's exceedingly rare. And the key message here is that the vast majority of these cases are actually with invasive cancer. So when you're communicating with urology colleagues or oncology colleagues,",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'cocktail', 'concept_id': 'C0678420', 'confidence': 1.0}, {'entity': 'markers', 'concept_id': 'C0181734', 'confidence': 0.890313982963562}, {'entity': 'intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate diagnosis', 'concept_id': 'C0011900', 'confidence': 0.7927443981170654}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'basal cells', 'concept_id': 'C0596155', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}, {'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}], [{'entity': 'Enlarged nuclei', 'concept_id': 'C4013177', 'confidence': 0.7774685621261597}, {'entity': 'size', 'concept_id': 'C0456389', 'confidence': 1.0}, {'entity': 'normal', 'concept_id': 'C0205307', 'confidence': 1.0}], [{'entity': 'Intraductal carcinoma', 'concept_id': 'C0007124', 'confidence': 1.0}, {'entity': 'prostate', 'concept_id': 'C0033572', 'confidence': 1.0}, {'entity': 'invasion', 'concept_id': 'C1269955', 'confidence': 1.0}, {'entity': 'colonization', 'concept_id': 'C4289767', 'confidence': 1.0}, {'entity': 'adjacent', 'concept_id': 'C0205117', 'confidence': 1.0}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}], [{'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'benign gland', 'concept_id': 'C0205183', 'confidence': 0.7986565828323364}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_980",
"caption_rating": "7"
},
{
"": "1006990",
"caption": "Patient had positive nucleic acid amplification testing for chlamydia, indicating chlamydia proctitis.",
"image_path": "sDFjOtMAYrk_image_757283d5-c995-4a15-9f3b-7b4fcc051194.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "[]",
"noisy_text": " is probably STI. And I said, well, it's really, really inflamed for STI. And lo and behold, she was right. The patient had positive nucleic acid amplification testing for chlamydia. Plus, he had a history of syphilis in the past. So this is a chlamydia proctitis. And this just goes to show you how typically we say in STI proctitis, inflammation is mild to at most moderate, but you can see anything and everything under the sun when it comes to inflammatory colonic pathology and just keep an open mind. Yeah. And I'll be the first to admit that the history really, really helped in this case. No. Yes. Yes. We did immunostains to rule out CMB and",
"corrected_text": " is probably STI. And I said, well, it's really, really inflamed for STI. And lo and behold, she was right. The patient had positive nucleic acid amplification testing for chlamydia. Plus, he had a history of syphilis in the past. So this is a chlamydia proctitis. And this just goes to show you how typically we say in STI proctitis, inflammation is mild to at most moderate, but you can see anything and everything under the sun when it comes to inflammatory colonic pathology and just keep an open mind. Yeah. And I'll be the first to admit that the history really, really helped in this case. No. Yes. Yes. We did immunostains to rule out CMB and",
"med_umls_ids": "[[{'entity': 'Patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'nucleic acid amplification testing', 'concept_id': 'C0200932', 'confidence': 0.938366174697876}, {'entity': 'chlamydia', 'concept_id': 'C0008148', 'confidence': 1.0}, {'entity': 'chlamydia proctitis', 'concept_id': 'C0149856', 'confidence': 1.0}], [{'entity': 'Inflammatory', 'concept_id': 'C0333348', 'confidence': 1.0}, {'entity': 'pathology', 'concept_id': 'C0030664', 'confidence': 1.0}, {'entity': 'degrees', 'concept_id': 'C0449286', 'confidence': 1.0}, {'entity': 'inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}], [{'entity': 'History', 'concept_id': 'C0019664', 'confidence': 1.0}, {'entity': 'diagnosing', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'STI', 'concept_id': 'C0036916', 'confidence': 1.0}, {'entity': 'proctitis', 'concept_id': 'C0033246', 'confidence': 0.9999999403953552}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_981",
"caption_rating": "9"
},
{
"": "1008703",
"caption": "Histopathological examination of prostate cancer with staining for nuclear and membranous wispy cytoplasmic stain, hemoglobin cytokeratin, and predominantly negative racemase.",
"image_path": "iklRyY1nBIE_image_34412311-c4b7-43e7-a39e-2295e0cd94dd.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['Prostate cancer with aberrant P63 staining expression.', 'Prostate cancer with aberrant P63 staining expression.']",
"noisy_text": " Again, you want to look at your internal control. These are the glands that were comfortable or benign. You can see they're staining for both nuclear stain and membranous wispy cytoplasmic stain, which is the hemoglobin cytokeratin. In this baccalaureate case, the racemase was predominantly negative. There's a hint of staining in areas, but it's predominantly negative. What is striking, what is very striking, is the fact that the P63 is diffusely positive, which they found very odd. And so this is a very, very fascinating case of prostatic adenocarcinoma with aberrant P63 expression, or what some people call P63 prostate prostate cancer. And I'll show you, this is the index case, but I'll show you a few other cases. Because it's a very, very fascinating, it's an",
"corrected_text": " Again, you want to look at your internal control. These are the glands that were comfortable or benign. You can see they're staining for both nuclear stain and membranous wispy cytoplasmic stain, which is the hemoglobin cytokeratin. In this baccalaureate case, the racemase was predominantly negative. There's a hint of staining in areas, but it's predominantly negative. What is striking, what is very striking, is the fact that the P63 is diffusely positive, which they found very odd. And so this is a very, very fascinating case of prostatic adenocarcinoma with aberrant P63 expression, or what some people call P63 prostate prostate cancer. And I'll show you, this is the index case, but I'll show you a few other cases. Because it's a very, very fascinating, it's an",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'examination', 'concept_id': 'C0031809', 'confidence': 1.0}, {'entity': 'prostate cancer', 'concept_id': 'C0376358', 'confidence': 1.0}, {'entity': 'staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'nuclear', 'concept_id': 'C0521447', 'confidence': 1.0}, {'entity': 'membranous', 'concept_id': 'C0025255', 'confidence': 1.0}, {'entity': 'wispy cytoplasmic stain', 'concept_id': 'C0010834', 'confidence': 0.6738394498825073}, {'entity': 'hemoglobin cytokeratin', 'concept_id': 'C0010803', 'confidence': 0.7460406422615051}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'racemase', 'concept_id': 'C0034503', 'confidence': 1.0}], [{'entity': 'Diffuse positive P63 staining', 'concept_id': 'C0205219', 'confidence': 0.5406208634376526}, {'entity': 'expression', 'concept_id': 'C0017262', 'confidence': 0.9999998807907104}, {'entity': 'prostatic adenocarcinoma', 'concept_id': 'C0007112', 'confidence': 1.0}, {'entity': 'P63 prostate cancer', 'concept_id': 'C0376358', 'confidence': 0.7053087949752808}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_982",
"caption_rating": "7"
},
{
"": "1008740",
"caption": "Reactive cytologic atypia can be seen in cases of treatment effect, such as chemotherapy or radiation.",
"image_path": "sDFjOtMAYrk_image_9c82fad4-2cd4-46e7-ad2a-ea44f4a70f53.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Hematopathology', 'Dermatopathology']",
"roi_text": "['prominent nucleoli', 'reactive cytologic atypia', 'chemotherapy or radiation', 'cancer', 'inflammatory bowel disease', 'prominent nucleoli', 'reactive cytologic atypia', 'chemotherapy or radiation', 'cancer', 'inflammatory bowel disease', 'prominent nucleoli', 'reactive cytologic atypia', 'chemotherapy or radiation', 'cancer', 'inflammatory bowel disease']",
"noisy_text": " I'm missing it. Okay. I think what's catching my eye for the most part is the prominent nucleolide, but what would you say about the NC ratio? Yeah, I think overall it's low. You have lots, loads of cytoplasm. Even though the nuclei are big, you have loads of cytoplasm. So, with this morphology, first of all, the question was, you know, inflammatory bowel disease. Okay, maybe, but the cytology is not great for the degree of reactive epithelial changes. Although you can have some crazy looking inflammatory bowel disease cases, it's really crazy. When I see crazy bizarre epithelial atypia, I think about treatment effect, either chemotherapy or radiation. Both of them can give you this crazy cytologic atypia that sometimes may actually make you think of cancer. We've got a couple of cases received in consultation. I'm remembering one specifically in the stomach where the question is, what about this cancer? And it wasn't. It was just crazy reactive epithelial changes in a patient who we didn't know, but the patient had received radiotherapy for lung cancer. And it definitely looked a lot like malignancy, but there was something not right about it. So, this patient was receiving at the same time chemotherapy for his pancreatic cancer. One thing you can see in patients, especially when they're receiving radiation,",
"corrected_text": " I'm missing it. Okay. I think what's catching my eye for the most part is the prominent nucleoli, but what would you say about the NC ratio? Yeah, I think overall it's low. You have lots, loads of cytoplasm. Even though the nuclei are big, you have loads of cytoplasm. So, with this morphology, first of all, the question was, you know, inflammatory bowel disease. Okay, maybe, but the cytology is not great for the degree of reactive epithelial changes. Although you can have some crazy looking inflammatory bowel disease cases, it's really crazy. When I see crazy bizarre epithelial atypia, I think about treatment effect, either chemotherapy or radiation. Both of them can give you this reactive cytologic atypia that sometimes may actually make you think of cancer. We've got a couple of cases received in consultation. I'm remembering one specifically in the stomach where the question is, what about this cancer? And it wasn't. It was just crazy reactive epithelial changes in a patient who we didn't know, but the patient had received radiotherapy for lung cancer. And it definitely looked a lot like malignancy, but there was something not right about it. So, this patient was receiving at the same time chemotherapy for his pancreatic cancer. One thing you can see in patients, especially when they're receiving radiation,",
"med_umls_ids": "[[{'entity': 'Prominent', 'concept_id': 'C0205402', 'confidence': 0.9999999403953552}, {'entity': 'nucleoli', 'concept_id': 'C0007609', 'confidence': 0.8710004091262817}, {'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'NC', 'concept_id': 'C0027964', 'confidence': 1.0}, {'entity': 'ratio', 'concept_id': 'C0456603', 'confidence': 1.0}, {'entity': 'low', 'concept_id': 'C0205251', 'confidence': 0.9999999403953552}], [{'entity': 'Reactive cytologic atypia', 'concept_id': 'C0333865', 'confidence': 0.8587049245834351}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'treatment effect', 'concept_id': 'C1518681', 'confidence': 1.0}, {'entity': 'chemotherapy', 'concept_id': 'C0013216', 'confidence': 1.0}, {'entity': 'radiation', 'concept_id': 'C0034519', 'confidence': 1.0}], [{'entity': 'Crazy', 'concept_id': 'C0424157', 'confidence': 0.6988691687583923}, {'entity': 'cancer', 'concept_id': 'C0006826', 'confidence': 0.9999998807907104}], [{'entity': 'Inflammatory bowel disease', 'concept_id': 'C0021390', 'confidence': 1.0}, {'entity': 'cytology', 'concept_id': 'C0010818', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_983",
"caption_rating": "9"
},
{
"": "1008719",
"caption": "Dilated vascular channels are present.",
"image_path": "8S4LeiO6Bbk_image_7a1fbb54-1a16-4c4d-ba48-7199d6c67247.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['siderophages']",
"noisy_text": " by these dilated vascular channels. Let's look at the bottom piece, which frequently do contain these papillary projections, which protrude into the lumina, these plump endothelial cells, and then at the periphery, more compressed vascular channels, which dissect between collagen bundles. And it's at the periphery one frequently sees extravasated erythrocytes, siderophages, and an infiltrate of lymphocytes. So targetoid hemocidiotic hemangioma. Sometimes it can be quite difficult to distinguish these from patch gage stage Kaposi's. And again, HHV8 stain will help you because these are routinely negative for HHVA and the Kaposi's, of course, will always stain with an HHV8 stain. And we will close out our discussion with slide number 12, which is kind of a cool case to end on. And we have two pieces of tissue here. And if",
"corrected_text": " by these dilated vascular channels. Let's look at the bottom piece, which frequently do contain these papillary projections, which protrude into the lumina, these plump endothelial cells, and then at the periphery, more compressed vascular channels, which dissect between collagen bundles. And it's at the periphery one frequently sees extravasated erythrocytes, siderophages, and an infiltrate of lymphocytes. So targetoid hemosiderotic hemangioma. Sometimes it can be quite difficult to distinguish these from patch gage stage Kaposi's. And again, HHV8 stain will help you because these are routinely negative for HHVA and the Kaposi's, of course, will always stain with an HHV8 stain. And we will close out our discussion with slide number 12, which is kind of a cool case to end on. And we have two pieces of tissue here. And if",
"med_umls_ids": "[[{'entity': 'Dilated', 'concept_id': 'C0700124', 'confidence': 0.9999999403953552}, {'entity': 'vascular channels', 'concept_id': 'C1336948', 'confidence': 0.7465758919715881}], [{'entity': 'Papillary projections', 'concept_id': 'C0016538', 'confidence': 0.7451471090316772}, {'entity': 'lumina', 'concept_id': 'C0524462', 'confidence': 0.845600426197052}], [{'entity': 'Enlarged endothelial cells', 'concept_id': 'C0423263', 'confidence': 0.7785332202911377}], [{'entity': 'Compressed vascular channels', 'concept_id': 'C1336948', 'confidence': 0.5993747711181641}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'bundles', 'concept_id': 'C3658308', 'confidence': 0.8706014752388}], [{'entity': 'Extravasated', 'concept_id': 'C0015376', 'confidence': 0.868863582611084}, {'entity': 'erythrocytes', 'concept_id': 'C0014772', 'confidence': 1.0}, {'entity': 'siderophages', 'concept_id': 'C1136253', 'confidence': 0.7251443266868591}, {'entity': 'infiltrate', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'lymphocytes', 'concept_id': 'C0024264', 'confidence': 1.0}, {'entity': 'periphery', 'concept_id': 'C1622967', 'confidence': 0.8329963088035583}], [{'entity': 'Targetoid hemosiderotic hemangioma', 'concept_id': 'C0346076', 'confidence': 0.9999999403953552}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}], [{'entity': 'targetoid hemosiderotic hemangioma', 'concept_id': 'C0346076', 'confidence': 0.9999999403953552}, {'entity': \"patch stage Kaposi's\", 'concept_id': 'C0280201', 'confidence': 0.7629613280296326}], [{'entity': 'HHV8', 'concept_id': 'C0036220', 'confidence': 1.0}, {'entity': 'stain', 'concept_id': 'C0038128', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_984",
"caption_rating": "8"
},
{
"": "1005326",
"caption": "Description of a benign-looking tumor with delicate stringy fine collagen and bland fibroblastic looking cells. The importance of recognizing the histologic pattern to correctly diagnose tumors.",
"image_path": "QDb68_G1HR4_image_adc17ea5-6336-438c-97f0-bc0b05d66e80.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['fibroblastic looking cells']",
"noisy_text": " Let me flip the condenser back so we can see it more clearly. So this is what it looks like without the condenser on, again, very delicate stringy fine collagen and in between these bland, bland, thin, not atypical at all, fibroblastic looking cells. And I could show anyone a picture of that, one picture. That does not look malignant, it looks totally benign by all of the rules that we usually use to assess malignancy histologically and cytologically. This is the most important take home point from this whole video. These tumors do not usually look malignant and because of that if you don't recognize the pattern, it is so easy to misdiagnose them as a benign thing. So I think a couple ways to avoid that is A, don't look at this and say, oh look it's a benign and it looks fibroblastic, let's call it a fibroma, don't do that. The other thing, one of my mentors, one of my greatest mentors, the one who made me decide to pursue academic medicine and teaching, Dr. Jay Rowe from Houston Methodist Hospital, what he told me, it was I think some great advice, he said if you see a lesion that you think is a neoplasm and you think it's a benign neoplasm but you don't know a name for it, don't just sign it out and diagnose it as benign neoplasm, not otherwise specified unless you're an expert in that particular subspecialty. Go and show it to an expert if you have a case like that and the reason is that maybe most of the time you'll be okay doing that but you're going to end up having things like this that are known entities that don't look malignant. In soft tissue we have quite a few of these, we have low grade fibromyxoid sarcoma, myxoid liposarcoma also looks totally benign most of the time unless you recognize the pattern. So this is another one of those tumors where the histologic pattern is really the key to recognizing the diagnosis. So I'm going to go in even higher power to convince you, yes these are sarcoma cells right here.",
"corrected_text": " Let me flip the condenser back so we can see it more clearly. So this is what it looks like without the condenser on, again, very delicate stringy fine collagen and in between these bland, bland, thin, not atypical at all, fibroblastic looking cells. And I could show anyone a picture of that, one picture. That does not look malignant, it looks totally benign by all of the rules that we usually use to assess malignancy histologically and cytology. This is the most important take home point from this whole video. These tumors do not usually look malignant and because of that if you don't recognize the pattern, it is so easy to misdiagnose them as a benign thing. So I think a couple ways to avoid that is A, don't look at this and say, oh look it's a benign and it looks fibroblastic, let's call it a fibroma, don't do that. The other thing, one of my mentors, one of my greatest mentors, the one who made me decide to pursue academic medicine and teaching, Dr. Jay Rowe from Houston Methodist Hospital, what he told me, it was I think some great advice, he said if you see a lesion that you think is a neoplasm and you think it's a benign neoplasm but you don't know a name for it, don't just sign it out and diagnose it as benign neoplasm, not otherwise specified unless you're an expert in that particular subspecialty. Go and show it to an expert if you have a case like that and the reason is that maybe most of the time you'll be okay doing that but you're going to end up having things like this that are known entities that don't look malignant. In soft tissue we have quite a few of these, we have low grade fibromyxoid sarcoma, myxoid liposarcoma also looks totally benign most of the time unless you recognize the pattern. So this is another one of those tumors where the histologic pattern is really the key to recognizing the diagnosis. So I'm going to go in even higher power to convince you, yes these are sarcoma cells right here.",
"med_umls_ids": "[[{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'benign-looking tumor', 'concept_id': 'C0086692', 'confidence': 0.5747699737548828}, {'entity': 'collagen', 'concept_id': 'C0009325', 'confidence': 0.9999998807907104}, {'entity': 'bland', 'concept_id': 'C0227475', 'confidence': 0.7435316443443298}, {'entity': 'fibroblastic', 'concept_id': 'C0016030', 'confidence': 0.8876925110816956}, {'entity': 'histologic', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_985",
"caption_rating": "8"
},
{
"": "1006926",
"caption": "Papillary configuration is the most common presentation of serous cyst adenocarcinoma.",
"image_path": "3mRB9j0eyVM_image_a564e201-b229-4bf5-9c1f-ede3903c371b.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gynecologic', 'Hematopathology', 'Soft tissue']",
"roi_text": "['atypia', 'infiltrated the underlying stroma', 'solid looking tumor', 'lining epithelial cells', 'infiltrative pattern', 'malignant tumor', 'invasive pattern', 'calcified body', 'rounded calcified bodies', 'papillary configuration', 'papillary structures', 'psammoma bodies']",
"noisy_text": " they will they will be infiltrative pattern, invasive pattern of the tumor, solid looking tumor with you can see here again, pepillary structures are very clearly seen even in the here. This is the picture of serous cyst adenocarcinoma, why we are saying it is carcinoma? Because the lining epithelial cells they have these they have the characteristic feature of atypia, atypia we all know hyperchromatism, pleomorphism, atypical mitotic activity, high MC ratio all these features are seen in these cells along with infiltration. These cells they have infiltrated the underlying stroma, when they have infiltrated the underlying stroma we call this is a malignant tumor, this is serous cyst adenocarcinoma. Now we come to the most common presentation of the serous cyst adenocarcinoma that is pepillary. So most of these tumors they show pepillary configuration that is their cells the epithelial cells they are found in the they form the pepillary configuration and that pepillae then ultimately they invade and they result in the invasiveness. And we all know that the serous cyst pepillary carcinoma we these adenocarcinoma of the ovary this frequently is associated with presence of somoma bodies and what is somoma body you all know from your 3rd year lectures and it was very frequently asked in your viva questions also in your viva examination also that somoma body is a calcified body, rounded calcified bodies are the somoma bodies and these are the typical features or typical findings that are commonly seen in the pepillary serous cyst adenocarcinoma of the ovary. Now we come to the mucinous tumors, again the mucinous tumors are again categorized in mucinous",
"corrected_text": " they will they will be infiltrative pattern, invasive pattern of the tumor, solid looking tumor with you can see here again, papillary structures are very clearly seen even in the here. This is the picture of serous cyst adenocarcinoma, why we are saying it is carcinoma? Because the lining epithelial cells they have these they have the characteristic feature of atypia, atypia we all know hyperchromatism, pleomorphism, atypical mitotic activity, high MC ratio all these features are seen in these cells along with infiltration. These cells they have infiltrated the underlying stroma, when they have infiltrated the underlying stroma we call this is a malignant tumor, this is serous cyst adenocarcinoma. Now we come to the most common presentation of the serous cyst adenocarcinoma that is papillary. So most of these tumors they show papillary configuration that is their cells the epithelial cells they are found in the they form the papillary configuration and that papillae then ultimately they invade and they result in the invasiveness. And we all know that the serous cyst papillary carcinoma we these adenocarcinoma of the ovary this frequently is associated with presence of psammoma bodies and what is somoma body you all know from your 3rd year lectures and it was very frequently asked in your viva questions also in your viva examination also that somoma body is a calcified body, rounded calcified bodies are the psammoma bodies and these are the typical features or typical findings that are commonly seen in the papillary serous cyst adenocarcinoma of the ovary. Now we come to the mucinous tumors, again the mucinous tumors are again categorized in mucinous",
"med_umls_ids": "[[{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'infiltrative', 'concept_id': 'C4527217', 'confidence': 1.0}, {'entity': 'invasive', 'concept_id': 'C0205281', 'confidence': 1.0}, {'entity': 'solid', 'concept_id': 'C0205208', 'confidence': 1.0}, {'entity': 'papillary structures', 'concept_id': 'C0030352', 'confidence': 0.7890171408653259}], [{'entity': 'tumor', 'concept_id': 'C0027651', 'confidence': 0.9999999403953552}, {'entity': 'serous cyst adenocarcinoma', 'concept_id': 'C0206701', 'confidence': 0.8984156847000122}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'atypia', 'concept_id': 'C0741302', 'confidence': 0.9999999403953552}, {'entity': 'infiltration', 'concept_id': 'C0332448', 'confidence': 1.0}, {'entity': 'malignant behavior', 'concept_id': 'C0004927', 'confidence': 0.7649628520011902}], [{'entity': 'Papillary configuration', 'concept_id': 'C1276436', 'confidence': 0.9154161214828491}, {'entity': 'presentation', 'concept_id': 'C0449450', 'confidence': 1.0}, {'entity': 'serous cyst adenocarcinoma', 'concept_id': 'C0206701', 'confidence': 0.8984156847000122}], [{'entity': 'Serous cyst papillary carcinoma', 'concept_id': 'C3839184', 'confidence': 0.9130419492721558}, {'entity': 'associated with', 'concept_id': 'C0332281', 'confidence': 1.0}, {'entity': 'presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'psammoma bodies', 'concept_id': 'C0391863', 'confidence': 1.0}, {'entity': 'calcified rounded bodies', 'concept_id': 'C0175895', 'confidence': 0.645065188407898}]]",
"magnification": "1.0",
"height": "720.0",
"width": "960.0",
"id": "test_986",
"caption_rating": "9"
},
{
"": "1005499",
"caption": "Possible presence of germ cell tumors, including malignant or immature teratoma.",
"image_path": "3mRB9j0eyVM_image_492b9987-d0e2-4954-aca0-c9489cd97900.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gynecologic', 'Hematopathology', 'Soft tissue']",
"roi_text": "['Immature teratoma with premature cells invading ovarian stroma', 'Choriocarcinoma of the ovary']",
"noisy_text": " germ cell tumors. You may find malignant teratoma or immature teratoma. Immature teratoma is commonly seen in case of the males. In females the most common teratoma is mature cystic teratoma that is benign tumor. This is immature teratoma, immature teratoma in which you see the premature cells, the neuronal cells and these are invading the stroma, the ovarian stroma. So these contain premature elements. Next is the choriocarcinoma of the ovary that is called non-gestational choriocarcinoma and it secretes human chorionic gonadotropin. It may be",
"corrected_text": " germ cell tumors. You may find malignant teratoma or immature teratoma. Immature teratoma is commonly seen in case of the males. In females the most common teratoma is mature cystic teratoma that is benign tumor. This is immature teratoma, immature teratoma in which you see the premature cells, the neuronal cells and these are invading the stroma, the ovarian stroma. So these contain premature elements. Next is the choriocarcinoma of the ovary that is called non-gestational choriocarcinoma and it secretes human chorionic gonadotropin. It may be",
"med_umls_ids": "[[{'entity': 'germ cell tumors', 'concept_id': 'C0205851', 'confidence': 1.0}, {'entity': 'malignant', 'concept_id': 'C0205282', 'confidence': 1.0}, {'entity': 'immature', 'concept_id': 'C0205252', 'confidence': 1.0}], [{'entity': 'Immature teratoma', 'concept_id': 'C0334520', 'confidence': 1.0}, {'entity': 'males', 'concept_id': 'C0086582', 'confidence': 1.0}, {'entity': 'mature', 'concept_id': 'C0205286', 'confidence': 1.0}, {'entity': 'cystic teratoma', 'concept_id': 'C0011649', 'confidence': 0.9999998807907104}, {'entity': 'benign', 'concept_id': 'C0205183', 'confidence': 1.0}, {'entity': 'females', 'concept_id': 'C0086287', 'confidence': 0.9999999403953552}], [{'entity': 'immature', 'concept_id': 'C0205252', 'confidence': 1.0}, {'entity': 'teratoma', 'concept_id': 'C0039538', 'confidence': 1.0}, {'entity': 'premature cells', 'concept_id': 'C0205252', 'confidence': 0.7552258372306824}, {'entity': 'neuronal cells', 'concept_id': 'C0027882', 'confidence': 0.7867127656936646}, {'entity': 'invade', 'concept_id': 'C1517574', 'confidence': 0.857607364654541}, {'entity': 'ovarian stroma', 'concept_id': 'C0227896', 'confidence': 1.0}], [{'entity': 'Choriocarcinoma', 'concept_id': 'C0008497', 'confidence': 1.0}, {'entity': 'ovary', 'concept_id': 'C0029939', 'confidence': 1.0}, {'entity': 'non-gestational choriocarcinoma', 'concept_id': 'C1135873', 'confidence': 1.0}, {'entity': 'secretes', 'concept_id': 'C1327616', 'confidence': 0.8702053427696228}, {'entity': 'human', 'concept_id': 'C0086418', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "960.0",
"id": "test_987",
"caption_rating": "8"
},
{
"": "1006020",
"caption": "Comparison of squamous morphology of MAC with desmoplastic tricholemmoma or syringoma.",
"image_path": "LlPaENuqzVQ_image_784fb44f-bfa3-44d3-811f-518068d88be6.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['Eosinophilic cells with squamous morphology', 'Fibromyxoid stroma', 'Diffuse dissection throughout the dermis', 'Eosinophilic cells with squamous morphology', 'Fibromyxoid stroma', 'Diffuse dissection throughout the dermis']",
"noisy_text": " We have a diagnosis called the surface of the sclerosing epithelial neoplasm. You have to go back and take more, another biopsy. MACs often will have a little more squamoid morphology like this. Can you see those kind of eosinophilic cells? They kind of look a little bit more like squamous cells a little bit. So that favors MAC more than like a desmoplastic tricho or even like a serendoma. A serendoma usually also is obviously much smaller. You can't take a shave biopsy and get an entire serendoma out. And usually the stroma is more prominent in the serendoma. Notice that this stroma is more fibromucinous. So this thing is kind of dissecting diffusely throughout the dermis here. I don't see",
"corrected_text": " We have a diagnosis called the surface of the sclerosing epithelial neoplasm. You have to go back and take more, another biopsy. MACs often will have a little more squamous morphology like this. Can you see those kind of eosinophilic cells? They kind of look a little bit more like squamous cells a little bit. So that favors MAC more than like a desmoplastic tricholemmoma or even like a syringoma. A syringoma usually also is obviously much smaller. You can't take a shave biopsy and get an entire syringoma out. And usually the stroma is more prominent in the syringoma. Notice that this stroma is more fibromyxoid. So this thing is kind of dissecting diffusely throughout the dermis here. I don't see",
"med_umls_ids": "[[{'entity': 'Diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'surface', 'concept_id': 'C0205148', 'confidence': 1.0}, {'entity': 'sclerosing', 'concept_id': 'C0036426', 'confidence': 0.833010733127594}, {'entity': 'epithelial neoplasm', 'concept_id': 'C1368683', 'confidence': 1.0}, {'entity': 'biopsy', 'concept_id': 'C0005558', 'confidence': 0.9999998807907104}], [{'entity': 'Comparison', 'concept_id': 'C1707455', 'confidence': 1.0}, {'entity': 'squamous', 'concept_id': 'C1182670', 'confidence': 0.9999998807907104}, {'entity': 'morphology', 'concept_id': 'C0332437', 'confidence': 0.9999999403953552}, {'entity': 'MAC', 'concept_id': 'C0009545', 'confidence': 0.9999999403953552}, {'entity': 'desmoplastic tricholemmoma', 'concept_id': 'C1275206', 'confidence': 0.9999999403953552}, {'entity': 'syringoma', 'concept_id': 'C0206673', 'confidence': 1.0}], [{'entity': 'Description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'fibromyxoid', 'concept_id': 'C0205766', 'confidence': 0.8987292051315308}, {'entity': 'stroma', 'concept_id': 'C0927195', 'confidence': 1.0}, {'entity': 'diffuse dissection', 'concept_id': 'C0205219', 'confidence': 0.7718934416770935}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_988",
"caption_rating": "7"
},
{
"": "1004803",
"caption": "Basal cell carcinoma with sebaceous differentiation should have clefting and palisading with obvious sebaceous differentiation.",
"image_path": "udoW6VSqsm4_image_4483f4d9-3fdd-47b6-b585-c7025cc11c86.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['sebaceoma', 'basal cell carcinoma', 'sebaceous differentiation', 'sebaceoma', 'basal cell carcinoma', 'sebaceous differentiation']",
"noisy_text": " I think we've called it sebaceous epithelium, but again I'm not a big fan of that term. And these look usually like this. They're usually small, round, skin-colored leaves. They kind of look like sebaceous epithelium. They usually come in as real-life basins, so nobody diagnoses these clinically correctly. So these are items in the differential diagnosis. Basal cell with sebaceous differentiation, if you're going to make that diagnosis, it generally needs to look like a basal cell with nice clefting and put the palisade in there and all that, and then have foci where there's obvious sebaceous differentiation. You'll see that on occasion. But I would probably call this sebaceoma, without thinking it's sort of synonymous with sebaceous epithelium. Now, is there any condition you have to worry about with these? With any",
"corrected_text": " I think we've called it sebaceous epithelium, but again I'm not a big fan of that term. And these look usually like this. They're usually small, round, skin-colored leaves. They kind of look like sebaceous epithelium. They usually come in as real-life basins, so nobody diagnoses these clinically correctly. So these are items in the differential diagnosis. Basal cell with sebaceous differentiation, if you're going to make that diagnosis, it generally needs to look like a basal cell with nice clefting and put the palisade in there and all that, and then have foci where there's obvious sebaceous differentiation. You'll see that on occasion. But I would probably call this sebaceoma, without thinking it's sort of synonymous with sebaceous epithelium. Now, is there any condition you have to worry about with these? With any",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'sebaceoma', 'concept_id': 'C1275210', 'confidence': 1.0}, {'entity': 'basal cell carcinoma', 'concept_id': 'C0007117', 'confidence': 1.0}, {'entity': 'sebaceous differentiation', 'concept_id': 'C1882988', 'confidence': 1.0}], [{'entity': 'Sebaceomas', 'concept_id': 'C1275210', 'confidence': 0.8855459690093994}, {'entity': 'small', 'concept_id': 'C0700321', 'confidence': 0.9999998807907104}, {'entity': 'round', 'concept_id': 'C0332490', 'confidence': 1.0}, {'entity': 'skin-colored', 'concept_id': 'C4476819', 'confidence': 0.8005288243293762}], [{'entity': 'Basal cell carcinoma', 'concept_id': 'C0007117', 'confidence': 1.0}, {'entity': 'sebaceous differentiation', 'concept_id': 'C1882988', 'confidence': 1.0}, {'entity': 'clefting', 'concept_id': 'C4021813', 'confidence': 0.8906428217887878}, {'entity': 'palisading', 'concept_id': 'C1622240', 'confidence': 0.8684062361717224}, {'entity': 'sebaceous differentiation', 'concept_id': 'C1882988', 'confidence': 1.0}], [{'entity': 'conditions', 'concept_id': 'C0012634', 'confidence': 0.8556983470916748}, {'entity': 'concern', 'concept_id': 'C2699424', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_989",
"caption_rating": "8"
},
{
"": "1008445",
"caption": "Perineurioma can be difficult to diagnose because it overlaps with low-grade fibromyxoid sarcoma histologically and on immunohistochemistry.",
"image_path": "QDb68_G1HR4_image_8772a4d0-5e6a-4322-9ff2-d521cda51a2d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Deep soft tissue', 'Perineurioma', 'Low-grade fibromyxoid sarcoma', 'Immunohistochemistry', 'Swirling growth', 'Deep soft tissue', 'Perineurioma', 'Low-grade fibromyxoid sarcoma', 'Immunohistochemistry', 'Swirling growth']",
"noisy_text": " involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is more of a difficult problem because perineurioma has a lot of overlap histologically with low-grade fibromyxoid sarcoma and also immunohistochemically. On immunostains, EMA, Clodin-1 and Glut-1 are three immunostains that will usually stain perineuriomas. The problem is that low-grade fibromyxoid sarcomas often express at least focal EMA, so that's a problem and additionally, the examples of low-grade fibromyxoid sarcoma that have dramatic swirling and whirling growth, those are the ones that have a perineurioma like pattern, the ones that mimic perineurioma. They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The",
"corrected_text": " involves the deep soft tissue. So that's another easy way of that plus CD34. Perineurioma is more of a difficult problem because perineurioma has a lot of overlap histologically with low-grade fibromyxoid sarcoma and also immunohistochemically. On immunostains, EMA, Clodin-1 and Glut-1 are three immunostains that will usually stain perineuriomas. The problem is that low-grade fibromyxoid sarcomas often express at least focal EMA, so that's a problem and additionally, the examples of low-grade fibromyxoid sarcoma that have dramatic swirling and whirling growth, those are the ones that have a perineurioma like pattern, the ones that mimic perineurioma. They also often or almost always express Clodin-1 at least according to some studies. So that's a real pitfall that it looks like a perineurioma, it stains like perineurioma, Glut-1 at least to my knowledge is usually negative but I think I've seen one case report that reported positive staining for Glut in a low-grade fibromyxoid sarcoma. So not usual but in any case, with that differential, what you have to do here is do some ancillary testing. The",
"med_umls_ids": "[[{'entity': 'CD34', 'concept_id': 'C0054953', 'confidence': 1.0}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'deep soft tissue tumors', 'concept_id': 'C0037579', 'confidence': 0.8622524738311768}], [{'entity': 'Perineurioma', 'concept_id': 'C0751691', 'confidence': 0.9999999403953552}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcoma', 'concept_id': 'C1275282', 'confidence': 0.8688398599624634}, {'entity': 'histologically', 'concept_id': 'C0205462', 'confidence': 1.0}, {'entity': 'immunohistochemistry', 'concept_id': 'C0021044', 'confidence': 0.9999998807907104}], [{'entity': 'EMA', 'concept_id': 'C0268596', 'confidence': 0.9999999403953552}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}, {'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'immunohistochemical stains', 'concept_id': 'C4317108', 'confidence': 0.9999999403953552}, {'entity': 'diagnose', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibrosarcomas', 'concept_id': 'C0016057', 'confidence': 1.0}, {'entity': 'EMA', 'concept_id': 'C0268596', 'confidence': 0.9999999403953552}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}], [{'entity': 'Low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'swirling', 'concept_id': 'C0233591', 'confidence': 0.7064549922943115}, {'entity': 'growth', 'concept_id': 'C0018270', 'confidence': 1.0}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'express', 'concept_id': 'C0017262', 'confidence': 0.8176293969154358}, {'entity': 'Clodin-1', 'concept_id': 'C3496132', 'confidence': 0.5473200082778931}], [{'entity': 'Glut-1', 'concept_id': 'C1504631', 'confidence': 1.0}, {'entity': 'negative', 'concept_id': 'C0205160', 'confidence': 0.9999999403953552}, {'entity': 'perineuriomas', 'concept_id': 'C0751691', 'confidence': 1.0}, {'entity': 'reports', 'concept_id': 'C0684224', 'confidence': 1.0}, {'entity': 'positive', 'concept_id': 'C1446409', 'confidence': 1.0}, {'entity': 'staining', 'concept_id': 'C0487602', 'confidence': 1.0}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'fibromyxoid sarcomas', 'concept_id': 'C1275282', 'confidence': 0.8123146891593933}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_990",
"caption_rating": "8"
},
{
"": "1006301",
"caption": "Presence of hemosiderin and lipid-laden cells in a cellular dermatofibroma with lipid accumulation.",
"image_path": "udoW6VSqsm4_image_2a63f541-31ba-4776-91c6-846c7a4b6c86.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Genitourinary', 'Breast pathology']",
"roi_text": "['Areas with hemosiderin', 'Areas with foamy appearance', 'Lipid-laden cells in cellular dermatofibroma']",
"noisy_text": " Like there are areas where there was hemosiderin. It's kind of hard to see from here, but I found some areas where there was hemosiderin, but some areas that were also a little foamy. Yeah, I'd say a little bit foamy. Scale of one to ten, that's probably about a ten with regard to foaming. So yeah, they're very lipidized. So this would be like a cellular dermatofibroma with lipidization. There's another type of dermatofibroma where you can see large atypical cells, or dermatofibroma with monster cells. Those can simulate cancer. This one didn't really have as many of those kinds of cells. Yeah, so",
"corrected_text": " Like there are areas where there was hemosiderin. It's kind of hard to see from here, but I found some areas where there was hemosiderin, but some areas that were also a little foamy. Yeah, I'd say a little bit foamy. Scale of one to ten, that's probably about a ten with regard to foaming. So yeah, they're very lipid-laden. So this would be like a cellular dermatofibroma with lipid accumulation. There's another type of dermatofibroma where you can see large atypical cells, or dermatofibroma with monster cells. Those can simulate cancer. This one didn't really have as many of those kinds of cells. Yeah, so",
"med_umls_ids": "[[{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'hemosiderin', 'concept_id': 'C0019113', 'confidence': 1.0}, {'entity': 'lipid-laden cells', 'concept_id': 'C0007584', 'confidence': 0.5060436129570007}, {'entity': 'cellular dermatofibroma', 'concept_id': 'C0002991', 'confidence': 0.833601713180542}, {'entity': 'lipid accumulation', 'concept_id': 'C0333574', 'confidence': 1.0}], [{'entity': 'dermatofibroma', 'concept_id': 'C0002991', 'confidence': 1.0}, {'entity': 'atypical cells', 'concept_id': 'C0333865', 'confidence': 1.0}, {'entity': 'monster cells', 'concept_id': 'C0007584', 'confidence': 0.7091032862663269}, {'entity': 'simulate', 'concept_id': 'C0284447', 'confidence': 0.9999998807907104}, {'entity': 'cancer', 'concept_id': 'C0006826', 'confidence': 0.9999998807907104}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_991",
"caption_rating": "8"
},
{
"": "1008470",
"caption": "Prior therapy, such as radiation or androgen deprivation therapy, can affect the appearance of the glands.",
"image_path": "iklRyY1nBIE_image_283e3876-761a-4b0a-aff5-50ea1dcea3b9.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Genitourinary', 'Hematopathology', 'Breast pathology']",
"roi_text": "['prostate glands', 'atrophy']",
"noisy_text": " are not that prominent. You see some prominent nuclei in some of the glands. But some other glands just look very bland. And it's almost like the case is sending mixed messages. In some areas, you see prominent nuclei. In some other areas, you don't see prominent nuclei. It looks very atrophic. And this obviously makes people very nervous when you see a lot of atrophy. The other issue is you could wonder, or you could ask, did this patient get any prior therapy? That's something else you want to know. Did this patient get prior radiation therapy? Did this patient get prior androgen deprivation therapy? In this baccalaureate case, the answer is no. The patient didn't get any prior therapy. So what do we do with these glands? They don't look like your typical prostate cancer. They look too atrophic. And they have",
"corrected_text": " are not that prominent. You see some prominent nuclei in some of the glands. But some other glands just look very bland. And it's almost like the case is sending mixed messages. In some areas, you see prominent nuclei. In some other areas, you don't see prominent nuclei. It looks very atrophic. And this obviously makes people very nervous when you see a lot of atrophy. The other issue is you could wonder, or you could ask, did this patient get any prior therapy? That's something else you want to know. Did this patient get prior radiation therapy? Did this patient get prior androgen deprivation therapy? In this baccalaureate case, the answer is no. The patient didn't get any prior therapy. So what do we do with these glands? They don't look like your typical prostate cancer. They look too atrophic. And they have",
"med_umls_ids": "[[{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'prostate glands', 'concept_id': 'C0033572', 'confidence': 0.8152219653129578}, {'entity': 'messages', 'concept_id': 'C0470166', 'confidence': 1.0}, {'entity': 'cell nuclei', 'concept_id': 'C0007610', 'confidence': 1.0}, {'entity': 'bland', 'concept_id': 'C0227475', 'confidence': 0.7435316443443298}, {'entity': 'atrophic', 'concept_id': 'C0151514', 'confidence': 1.0}], [{'entity': 'Presence', 'concept_id': 'C0150312', 'confidence': 1.0}, {'entity': 'atrophy', 'concept_id': 'C0333641', 'confidence': 1.0}, {'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}], [{'entity': 'therapy', 'concept_id': 'C0039798', 'confidence': 0.9999999403953552}, {'entity': 'radiation', 'concept_id': 'C0034519', 'confidence': 1.0}, {'entity': 'androgen deprivation therapy', 'concept_id': 'C0279492', 'confidence': 1.0}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'glands', 'concept_id': 'C1285092', 'confidence': 0.9999999403953552}], [{'entity': 'patient', 'concept_id': 'C0030705', 'confidence': 1.0}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'therapy', 'concept_id': 'C0039798', 'confidence': 0.9999999403953552}]]",
"magnification": "2.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_992",
"caption_rating": "8"
},
{
"": "1008591",
"caption": "Inflammation is a common result of chemical gastritis.",
"image_path": "r7OA0Trj5hQ_image_e4ca3b4b-74d6-408a-8711-0e8944691e10.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['lamina propria edema', 'muscularis mucosa', 'neutrophils', 'eosinophils', 'stomach', 'esophagus', 'enteritis', 'colitis', 'lamina propria edema', 'muscularis mucosa', 'neutrophils', 'eosinophils', 'stomach', 'esophagus', 'enteritis', 'colitis']",
"noisy_text": " Lamina propria edema and muscularis mucosa coming into the lamina propria. These are the three criterias. When you see it in the anterobiopsy, think of chemical gastritis that can be seen in biliary reflux or NSAID use. Lot of inflammation results. Remember I told you if you see more than five neutrophils, more than five eosinophils sitting in the lamina propria or more than 15 eosinophils per high power field, that is a eosinophilic gastritis, if it is from the stomach. If it is esophagus, it is eosinophilic esophagitis, eosinophilic entritis, eosinophilic colitis. So eosinophilic",
"corrected_text": " Lamina propria edema and muscularis mucosa coming into the lamina propria. These are the three criterias. When you see it in the antral biopsy, think of chemical gastritis that can be seen in biliary reflux or NSAID use. Lot of inflammation results. Remember I told you if you see more than five neutrophils, more than five eosinophils sitting in the lamina propria or more than 15 or more eosinophils per high power field, that is a eosinophilic gastritis, if it is from the stomach. If it is esophagus, it is eosinophilic esophagitis, eosinophilic enteritis, eosinophilic colitis. So eosinophilic",
"med_umls_ids": "[[{'entity': 'Lamina propria edema', 'concept_id': 'C1179187', 'confidence': 0.7593827247619629}, {'entity': 'muscularis mucosa', 'concept_id': 'C0225357', 'confidence': 0.9999998807907104}, {'entity': 'lamina propria', 'concept_id': 'C1179187', 'confidence': 1.0}, {'entity': 'criteria', 'concept_id': 'C0243161', 'confidence': 0.9999998807907104}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}], [{'entity': 'Inflammation', 'concept_id': 'C0021368', 'confidence': 1.0}, {'entity': 'chemical gastritis', 'concept_id': 'C2830012', 'confidence': 1.0}], [{'entity': 'Eosinophilic gastritis', 'concept_id': 'C0267154', 'confidence': 1.0}, {'entity': 'diagnosed', 'concept_id': 'C0011900', 'confidence': 1.0}, {'entity': 'eosinophils', 'concept_id': 'C0014467', 'confidence': 1.0}, {'entity': 'stomach', 'concept_id': 'C0038351', 'confidence': 1.0}], [{'entity': 'Eosinophilic esophagitis', 'concept_id': 'C0341106', 'confidence': 0.9999999403953552}, {'entity': 'eosinophilic enteritis', 'concept_id': 'C1262481', 'confidence': 1.0}, {'entity': 'eosinophilic colitis', 'concept_id': 'C0267448', 'confidence': 1.0}, {'entity': 'diagnoses', 'concept_id': 'C0011900', 'confidence': 1.0}]]",
"magnification": "1.0",
"height": "720.0",
"width": "1280.0",
"id": "test_993",
"caption_rating": "7"
},
{
"": "1007742",
"caption": "Likely neoplastic process with eosinophilic ball cells in the dermis.",
"image_path": "LlPaENuqzVQ_image_3bf63745-dc8d-43a8-87e1-603213f9e035.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Breast pathology']",
"roi_text": "['neoplasm', 'dermis', 'eosinophilic ball cells', 'malignant', 'benign', 'necrosis']",
"noisy_text": " OK, let's give this one a go. Yeah, I can do this one. So looks like we have a, I mean, I'm thinking this is probably malignant. Oh, sorry, it's not inflammatory. It's some proliferation of cells here. And this is likely, it's a eosinophilic, well-encapsulated. So you think it's a neoplasm? Yeah, it's a neoplastic process that it's, yeah. So I'm seeing eosinophilic ball cells in the dermis. I don't think that I can say much more at this point. You can, you can. So do you think it's epithelial or non-epithelial? It's probably not epithelial. Good, good, good. And you know, at low power, that's fine. You can say probably this, because you're going to confirm it when you go to higher magnitudes. That's perfectly fine. At low power, sometimes you can make an instant diagnosis. If you see molluscum bodies at low power, you just move on to the next case. Or you see herpes varus, you're gone, you're finished. You don't have to waste time on it anymore. But if it's something like this, you say, well, yeah, it looks like it's probably non-epithelial. Sometimes you can get spindle-shaped cells in an epithelial neoplasm, like a squamous cell, spindle cell, squamous cell. So we're not sure, but you're right. At low power, it seems like it's probably going to be non-epithelial. Certainly doesn't look like any typical epithelial structure. And it's interesting. You said it looks kind of well-circumscribed. I agree. But it's got a, this is a pretty low power view, and it's a pretty big specimen. So it's large, and it's kind of bottom-heavy. So you said at low power, you thought it was malignant. So why did you say malignant? Sorry, I meant neoplastic. I don't think, I mean, it looks very well-capsulated, and it looks like it's probably completely removed. So I actually, I favor benign, but it might be benign. Yeah, I agree, it could be benign. But it does have a couple of features a little bit weird. It's bottom-heavy, which that kind of makes you say, well, you be careful, because bottom-heavy neoplasm can sometimes be malignant, even though they kind of look well-circumscribed. It's a little bit asymmetrical. We draw a line down the middle of it. I mean, this little piece over here is kind of sticking out versus over here. So it may be benign, because it seems to be well-circumscribed, but it's got a couple of criteria that we wonder at low power. Maybe we're going to make sure that it's not malignant. This may even be some necrosis on moss in here, which is another feature of malignant. So we're going to have magnification. Let's see what",
"corrected_text": " OK, let's give this one a go. Yeah, I can do this one. So looks like we have a, I mean, I'm thinking this is probably malignant. Oh, sorry, it's not inflammatory. It's some proliferation of cells here. And this is likely, it's a eosinophilic, well-encapsulated. So you think it's a neoplasm? Yeah, it's a neoplastic process that it's, yeah. So I'm seeing eosinophilic ball cells in the dermis. I don't think that I can say much more at this point. You can, you can. So do you think it's epithelial or non-epithelial? It's probably not epithelial. Good, good, good. And you know, at low power, that's fine. You can say probably this, because you're going to confirm it when you go to higher magnitudes. That's perfectly fine. At low power, sometimes you can make an instant diagnosis. If you see molluscum bodies at low power, you just move on to the next case. Or you see herpes varus, you're gone, you're finished. You don't have to waste time on it anymore. But if it's something like this, you say, well, yeah, it looks like it's probably non-epithelial. Sometimes you can get spindle-shaped cells in an epithelial neoplasm, like a squamous cell, spindle cell, squamous cell. So we're not sure, but you're right. At low power, it seems like it's probably going to be non-epithelial. Certainly doesn't look like any typical epithelial structure. And it's interesting. You said it looks kind of well-circumscribed. I agree. But it's got a, this is a pretty low power view, and it's a pretty big specimen. So it's large, and it's kind of bottombulky. So you said at low power, you thought it was malignant. So why did you say malignant? Sorry, I meant neoplastic. I don't think, I mean, it looks very well-capsulated, and it looks like it's probably completely removed. So I actually, I favor benign, but it might be benign. Yeah, I agree, it could be benign. But it does have a couple of features a little bit weird. It's bottombulky, which that kind of makes you say, well, you be careful, because bottombulky neoplasm can sometimes be malignant, even though they kind of look well-circumscribed. It's a little bit asymmetrical. We draw a line down the middle of it. I mean, this little piece over here is kind of sticking out versus over here. So it may be benign, because it seems to be well-circumscribed, but it's got a couple of criteria that we wonder at low power. Maybe we're going to make sure that it's not malignant. This may even be some necrosis on moss in here, which is another feature of malignant. So we're going to have magnification. Let's see what",
"med_umls_ids": "[[{'entity': 'neoplastic process', 'concept_id': 'C0027671', 'confidence': 1.0}, {'entity': 'eosinophilic ball cells', 'concept_id': 'C0682547', 'confidence': 0.8429232835769653}, {'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}], [{'entity': 'Uncertain', 'concept_id': 'C0087130', 'confidence': 0.9999998807907104}, {'entity': 'neoplasm', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'epithelial', 'concept_id': 'C0221908', 'confidence': 1.0}, {'entity': 'non-epithelial', 'concept_id': 'C0809966', 'confidence': 0.7444443106651306}], [{'entity': 'Specimen', 'concept_id': 'C0370003', 'confidence': 1.0}, {'entity': 'well-circumscribed', 'concept_id': 'C1707398', 'confidence': 0.9430561065673828}, {'entity': 'features', 'concept_id': 'C1521970', 'confidence': 1.0}, {'entity': 'suspicion', 'concept_id': 'C0242114', 'confidence': 1.0}, {'entity': 'malignancy', 'concept_id': 'C0006826', 'confidence': 1.0}, {'entity': 'bottombulky', 'concept_id': 'C1511276', 'confidence': 0.5303326845169067}, {'entity': 'asymmetrical', 'concept_id': 'C0332514', 'confidence': 1.0}], [{'entity': 'magnification', 'concept_id': 'C5197828', 'confidence': 0.9129886031150818}, {'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_994",
"caption_rating": "8"
},
{
"": "1007061",
"caption": "The lesion described could be a fibroma or an acquired digital fibrokeratoma. Acquired digital fibromas are angiofibromas involving distal extremities. Diagnosis in this case is rudimentary supernumerary digit.",
"image_path": "8S4LeiO6Bbk_image_185dfddb-aa46-4460-b27f-05e4a2580681.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "[]",
"noisy_text": " fibroma or an acquired digital fibrocarotoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an acral surface. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trisected shade biopsy specimen and if we zoom in and study this lesion on low power we can see that the epidermis is hyperplastic characterized by",
"corrected_text": " fibroma or an acquired digital fibrokeratoma and if we had this lesion with the same configuration but wiped out or subtracted out the nerve fascicles we would have an acquired digital fibroma and acquired digital fibromas are nothing more than angiofibromas involving an distal extremities. So in this particular instance, diagnosis rudimentary supernumerary digit. Moving on to slide number seven, slide number seven we have a trichilemmal cyst biopsy specimen and if we zoom in and study this lesion on low power we can see that the epidermis is hyperplastic characterized by",
"med_umls_ids": "[[{'entity': 'lesion', 'concept_id': 'C0221198', 'confidence': 0.9999998807907104}, {'entity': 'fibroma', 'concept_id': 'C0016045', 'confidence': 1.0}, {'entity': 'acquired', 'concept_id': 'C0439661', 'confidence': 1.0}, {'entity': 'Acquired digital fibromas', 'concept_id': 'C0346045', 'confidence': 0.9422788023948669}, {'entity': 'angiofibromas', 'concept_id': 'C0206731', 'confidence': 1.0}, {'entity': 'distal extremities', 'concept_id': 'C0015385', 'confidence': 0.852354884147644}, {'entity': 'Diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'case', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'rudimentary supernumerary digit', 'concept_id': 'C0152427', 'confidence': 0.8142021894454956}], [{'entity': 'Histopathological', 'concept_id': 'C0677043', 'confidence': 0.9437630772590637}, {'entity': 'description', 'concept_id': 'C0678257', 'confidence': 1.0}, {'entity': 'trichilemmal cyst', 'concept_id': 'C2266788', 'confidence': 1.0}, {'entity': 'hyperplastic epidermis', 'concept_id': 'C4748317', 'confidence': 0.7633129358291626}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_995",
"caption_rating": "7"
},
{
"": "1009462",
"caption": "Rare reports of cases with a full-blown high-grade pleomorphic sarcoma-like appearance or osteosarcomatous areas have been described.",
"image_path": "QDb68_G1HR4_image_28c0e68e-a4f7-48da-9edb-09482f347963.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Soft tissue', 'Dermatopathology', 'Hematopathology']",
"roi_text": "[]",
"noisy_text": " Now I've been telling you and highlighting how important it is to know that these tumors don't have atypia. Now again that's another rule that's sometimes broken I think it's important to learn that the most common the most common appearance is a benign looking tumor that doesn't look atypical that's important because I think that's the one those are the ones that are easy to miss but it is worth noting that a subset a small subset maybe around 10% of cases can have areas with increased cellularity, scattered pleomorphism, a round cell or epithelioid cell appearance. There have also been rare reports of cases that truly have a full-blown high-grade pleomorphic sarcoma like appearance like that they've transitioned into high-grade sarcoma or I think even osteosarcomatous areas have been described. These are all really rare exceptions to the rule but I and I think it's again much more important for the general pathologists to know that this very bland benign looking appearance because this",
"corrected_text": " Now I've been telling you and highlighting how important it is to know that these tumors don't have atypia. Now again that's another rule that's sometimes broken I think it's important to learn that the most common the most common appearance is a benign looking tumor that doesn't look atypical that's important because I think that's the one those are the ones that are easy to miss but it is worth noting that a subset a small subset maybe around 10% of cases can have areas with increased cellularity, scattered pleomorphism, a round cell or epithelioid cell appearance. There have also been rare reports of cases that truly have a full-blown high-grade pleomorphic sarcoma like appearance like that they've transitioned into high-grade sarcoma or I think even osteosarcomatous areas have been described have been described. These are all really rare exceptions to the rule but I and I think it's again much more important for the general pathologists to know that this very bland benign looking appearance because this",
"med_umls_ids": "[[{'entity': 'tumors', 'concept_id': 'C0027651', 'confidence': 1.0}, {'entity': 'benign', 'concept_id': 'C0205183', 'confidence': 1.0}, {'entity': 'atypia', 'concept_id': 'C0741302', 'confidence': 0.9999999403953552}], [{'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'increased', 'concept_id': 'C0205217', 'confidence': 1.0}, {'entity': 'cellularity', 'concept_id': 'C0178539', 'confidence': 0.9999999403953552}, {'entity': 'scattered', 'concept_id': 'C0439742', 'confidence': 1.0}, {'entity': 'pleomorphism', 'concept_id': 'C0032219', 'confidence': 1.0}, {'entity': 'round cell', 'concept_id': 'C0487470', 'confidence': 1.0}, {'entity': 'epithelioid cell', 'concept_id': 'C0014603', 'confidence': 0.9999999403953552}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}], [{'entity': 'Rare', 'concept_id': 'C0521114', 'confidence': 1.0}, {'entity': 'reports', 'concept_id': 'C0684224', 'confidence': 1.0}, {'entity': 'cases', 'concept_id': 'C0868928', 'confidence': 1.0}, {'entity': 'high-grade', 'concept_id': 'C1512433', 'confidence': 0.9347730875015259}, {'entity': 'pleomorphic', 'concept_id': 'C1514164', 'confidence': 1.0}, {'entity': 'appearance', 'concept_id': 'C0233426', 'confidence': 1.0}, {'entity': 'osteosarcomatous areas', 'concept_id': 'C0279602', 'confidence': 0.7822340130805969}]]",
"magnification": "0.0",
"height": "1080.0",
"width": "1920.0",
"id": "test_996",
"caption_rating": "8"
},
{
"": "1009464",
"caption": "Colonic biopsy showing normal epithelium with a single layer of cells and mucin present.",
"image_path": "r7OA0Trj5hQ_image_d83c895f-5036-45e0-aeac-e8e88adc4f94.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['acidic intestinal mucin taking Asian blue color', 'colonic biopsy showing normal epithelium with a single layer of cells and mucin present.', 'acidic intestinal mucin taking Asian blue color', 'colonic biopsy showing normal epithelium with a single layer of cells and mucin present.']",
"noisy_text": " the acidic mucin is taking the asian blue color, whereas the gastric mucin is taking the neutral mucin, pink color, PAS. Asian blue stains the acidic intestinal mucin into blue. That is very essential to remember. Here, what is happening? This is a colonic biopsy. You see the normal epithelium, single strand, single epithelium, lot of mucin. Looks normal now, normal. When you travel all along, what's happening here? You see the difference between this and this. Here, single layer of cells, mucin is present, whereas here,",
"corrected_text": " the acidic mucin is taking the asian blue color, whereas the gastric mucin is taking the neutral mucin, pink color, PAS. Asian blue stains the acidic intestinal mucin into blue. That is very essential to remember. Here, what is happening? This is a colonic biopsy. You see the normal epithelium, single strand, single epithelium, lot of mucin. Looks normal now, normal. When you travel all along, what's happening here? You see the difference between this and this. Here, single layer of cells, mucin is present, whereas here,",
"med_umls_ids": "[[{'entity': 'Differentiation', 'concept_id': 'C0007589', 'confidence': 1.0}, {'entity': 'acidic', 'concept_id': 'C0001128', 'confidence': 1.0}, {'entity': 'gastric mucin', 'concept_id': 'C0017135', 'confidence': 1.0}, {'entity': 'Asian blue', 'concept_id': 'C1197245', 'confidence': 0.8144476413726807}, {'entity': 'pink color', 'concept_id': 'C0332585', 'confidence': 0.9999998807907104}, {'entity': 'PAS', 'concept_id': 'C0030125', 'confidence': 1.0}, {'entity': 'stains', 'concept_id': 'C0038128', 'confidence': 1.0}], [{'entity': 'Colonic biopsy', 'concept_id': 'C0192867', 'confidence': 1.0}, {'entity': 'cells', 'concept_id': 'C0007584', 'confidence': 0.9999999403953552}, {'entity': 'mucin', 'concept_id': 'C0026682', 'confidence': 1.0}]]",
"magnification": "0.0",
"height": "720.0",
"width": "1280.0",
"id": "test_997",
"caption_rating": "9"
},
{
"": "1006672",
"caption": "Normal epithelium, low-grade dysplasia, and high-grade dysplasia can be seen in one picture.",
"image_path": "r7OA0Trj5hQ_image_fac10052-2d43-4ed1-83bb-3a07863f42c4.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Gastrointestinal', 'Dermatopathology', 'Hematopathology']",
"roi_text": "['Stroma running in between', 'Crowded appearance', 'Back-to-back glands', 'Cribriform appearance', 'Intraglandular epithelial proliferation', 'Stroma running in between', 'Crowded appearance', 'Back-to-back glands', 'Cribriform appearance', 'Intraglandular epithelial proliferation', 'Stroma running in between', 'Crowded appearance', 'Back-to-back glands', 'Cribriform appearance', 'Intraglandular epithelial proliferation']",
"noisy_text": " you can see some stroma running in between. However, it may be crowded. See here, one gland, another gland. You can see the nice stroma in between. These are back-to-back glands. But see here, this is one gland, this is one gland, this is one gland. But no stroma in between. So these are cribriform, which is intraglandular. Epithelial proliferation is happening within the gland, which is a future of high-grade dysplasia. So normal epithelium, low-grade dysplasia, high-grade dysplasia in one picture. Thanks to Google. I don't know the source, but I thank the person, anonymous person. So those are",
"corrected_text": " you can see some stroma running in between. However, it may be crowded. See here, one gland, another gland. You can see the nice stroma in between. These are back-to-back glands. But see here, this is one gland, this is one gland, this is one gland. But no stroma in between. So these are cribriform, which is intraglandular. Epithelial proliferation is happening within the gland, which is a future of high-grade dysplasia. So normal epithelium, low-grade dysplasia, high-grade dysplasia in one picture. Thanks to Google. I don't know the source, but I thank the person, anonymous person. So those are",
"med_umls_ids": "[[{'entity': 'Intraglandular', 'concept_id': 'C4725341', 'confidence': 0.9096097350120544}, {'entity': 'epithelial proliferation', 'concept_id': 'C0334097', 'confidence': 1.0}, {'entity': 'high-grade dysplasia', 'concept_id': 'C1333110', 'confidence': 0.8831341862678528}], [{'entity': 'Normal epithelium', 'concept_id': 'C0014609', 'confidence': 0.8199569582939148}, {'entity': 'low-grade', 'concept_id': 'C1518005', 'confidence': 0.9270920157432556}, {'entity': 'dysplasia', 'concept_id': 'C0334044', 'confidence': 1.0}, {'entity': 'high-grade dysplasia', 'concept_id': 'C1333110', 'confidence': 0.8831341862678528}, {'entity': 'picture', 'concept_id': 'C0441468', 'confidence': 1.0}]]",
"magnification": "2.0",
"height": "720.0",
"width": "1280.0",
"id": "test_998",
"caption_rating": "7"
},
{
"": "1007060",
"caption": "The epidermis is hyperplastic and papillary, with altered quantified layer and some compact ortho and parakeratosis.",
"image_path": "8S4LeiO6Bbk_image_35e1e06c-3636-48f5-a522-44a08f05a70d.jpg",
"subset": "quilt",
"split": "val",
"pathology": "['Dermatopathology', 'Soft tissue', 'Neuropathology']",
"roi_text": "['hyperplastic epidermis', 'papillary epidermis', 'compact ortho', 'parakeratosis', 'patchy perivascular infiltrative lymphocytes', 'discrete columns and mounds of parakeratosis', 'dyskeratotic cells', 'verruciform xanthoma']",
"noisy_text": " that the epidermis is hyperplastic and gently papillated. The quantified layer is altered somewhat. We got some compact ortho and probably a little bit of pericaratosis here are to tell at this power. The underlying dermis contains a patchy perivascular infiltrative lymphocytes and if we move to higher power, we can confirm these findings. Lymphocytes, dilated vessels, papillomatosis, and epidermal hyperplasia. There are discrete columns and mounds of pericaratosis within the stratum corneum and some dyskeratotic cells within the underlying epidermis. One of the things when one sees these these columns of bright pink pericaratosis that one might think about would be a verruciform xanthoma because you'll remember we tend to get these vertical",
"corrected_text": " that the epidermis is hyperplastic and gently papillated. The quantified layer is altered somewhat. We got some compact ortho and probably a little bit of parakeratosis here are to tell at this power. The underlying dermis contains a patchy perivascular infiltrative lymphocytes and if we move to higher power, we can confirm these findings. Lymphocytes, dilated vessels, papillomatosis, and epidermal hyperplasia. There are discrete columns and mounds of parakeratosis within the stratum corneum and some dyskeratotic cells within the underlying epidermis. One of the things when one sees these these columns of bright pink pericaratosis that one might think about would be a verruciform xanthoma because you'remember we tend to get these vertical",
"med_umls_ids": "[[{'entity': 'epidermis', 'concept_id': 'C0014520', 'confidence': 1.0}, {'entity': 'hyperplastic', 'concept_id': 'C0020507', 'confidence': 1.0}, {'entity': 'papillary', 'concept_id': 'C0205312', 'confidence': 1.0}, {'entity': 'quantified', 'concept_id': 'C1709793', 'confidence': 0.6807526350021362}, {'entity': 'layer', 'concept_id': 'C0934502', 'confidence': 1.0}, {'entity': 'compact ortho', 'concept_id': 'C1333134', 'confidence': 0.7191344499588013}, {'entity': 'parakeratosis', 'concept_id': 'C0030436', 'confidence': 1.0}], [{'entity': 'dermis', 'concept_id': 'C0011646', 'confidence': 1.0}, {'entity': 'perivascular', 'concept_id': 'C0442165', 'confidence': 1.0}], [{'entity': 'Discrete columns', 'concept_id': 'C0227428', 'confidence': 0.6879350543022156}, {'entity': 'mounds', 'concept_id': 'C2717795', 'confidence': 0.736616313457489}, {'entity': 'parakeratosis', 'concept_id': 'C0030436', 'confidence': 1.0}, {'entity': 'stratum corneum', 'concept_id': 'C0221921', 'confidence': 1.0}, {'entity': 'dyskeratotic cells', 'concept_id': 'C1512098', 'confidence': 0.8970272541046143}, {'entity': 'epidermis', 'concept_id': 'C0014520', 'confidence': 1.0}], [{'entity': 'diagnosis', 'concept_id': 'C0011900', 'confidence': 0.9999998807907104}, {'entity': 'verruciform xanthoma', 'concept_id': 'C0346054', 'confidence': 0.9999999403953552}]]",
"magnification": "0.0",
"height": "758.0",
"width": "1920.0",
"id": "test_999",
"caption_rating": "8"
}
]
================================================
FILE: data/test/vqa/harvard_test.jsonl
================================================
{"question_id": 1, "question": "Has the patient been diagnosed with glaucoma?\n", "answer": "Yes.", "image": "slo_fundus_08003.jpg", "report": "86-year-old white, non-hispanic female diagnosed with glaucoma."}
{"question_id": 2, "question": "Is the patient undergoing treatment for glaucoma?\n", "answer": "The summary does not provide this information.", "image": "slo_fundus_08003.jpg", "report": "86-year-old white, non-hispanic female diagnosed with glaucoma."}
{"question_id": 3, "question": "Has the patient had any surgeries to treat glaucoma?\n", "answer": "The summary does not provide this information.", "image": "slo_fundus_08003.jpg", "report": "86-year-old white, non-hispanic female diagnosed with glaucoma."}
{"question_id": 4, "question": "Is the patient's glaucoma diagnosis recent?\n", "answer": "The summary does not provide this information.", "image": "slo_fundus_08003.jpg", "report": "86-year-old white, non-hispanic female diagnosed with glaucoma."}
{"question_id": 5, "question": "Has erythromycin ophthalmic ointment been prescribed for the patient's right eye?\n", "answer": "Yes.", "image": "slo_fundus_08008.jpg", "report": "The clinical note prescribes erythromycin ophthalmic ointment for the patient's right eye. The patient is referred to ophthalmology. No mention of glaucoma. Other conditions include goiter, rheumatoid arthritis, etc."}
{"question_id": 6, "question": "Is the patient currently being referred to ophthalmology?\n", "answer": "Yes.", "image": "slo_fundus_08008.jpg", "report": "The clinical note prescribes erythromycin ophthalmic ointment for the patient's right eye. The patient is referred to ophthalmology. No mention of glaucoma. Other conditions include goiter, rheumatoid arthritis, etc."}
{"question_id": 7, "question": "Is there any mention of the patient having glaucoma in the clinical note?\n", "answer": "No.", "image": "slo_fundus_08008.jpg", "report": "The clinical note prescribes erythromycin ophthalmic ointment for the patient's right eye. The patient is referred to ophthalmology. No mention of glaucoma. Other conditions include goiter, rheumatoid arthritis, etc."}
{"question_id": 8, "question": "Does the patient have a goiter as a coexisting condition?\n", "answer": "Yes.", "image": "slo_fundus_08008.jpg", "report": "The clinical note prescribes erythromycin ophthalmic ointment for the patient's right eye. The patient is referred to ophthalmology. No mention of glaucoma. Other conditions include goiter, rheumatoid arthritis, etc."}
{"question_id": 9, "question": "Is rheumatoid arthritis one of the patient's other conditions?\n", "answer": "Yes.", "image": "slo_fundus_08008.jpg", "report": "The clinical note prescribes erythromycin ophthalmic ointment for the patient's right eye. The patient is referred to ophthalmology. No mention of glaucoma. Other conditions include goiter, rheumatoid arthritis, etc."}
{"question_id": 10, "question": "Does the patient exhibit thinning of the temporal nerve fiber layer in the left eye?\n", "answer": "Yes.", "image": "slo_fundus_08009.jpg", "report": "Patient displays thin temporal os and hvf 24-2 shows corresponding inferior defects. Risk factors for glaucoma noted. Patient also has borderline diabetes, chronic anemia and a family history of macular degeneration."}
{"question_id": 11, "question": "Does the Humphrey Visual Field (HVF) 24-2 test indicate corresponding inferior visual field defects?\n", "answer": "Yes.", "image": "slo_fundus_08009.jpg", "report": "Patient displays thin temporal os and hvf 24-2 shows corresponding inferior defects. Risk factors for glaucoma noted. Patient also has borderline diabetes, chronic anemia and a family history of macular degeneration."}
{"question_id": 12, "question": "Are there noted risk factors for glaucoma in this patient's case?\n", "answer": "Yes.", "image": "slo_fundus_08009.jpg", "report": "Patient displays thin temporal os and hvf 24-2 shows corresponding inferior defects. Risk factors for glaucoma noted. Patient also has borderline diabetes, chronic anemia and a family history of macular degeneration."}
{"question_id": 13, "question": "Has the patient been diagnosed with borderline diabetes?\n", "answer": "Yes.", "image": "slo_fundus_08009.jpg", "report": "Patient displays thin temporal os and hvf 24-2 shows corresponding inferior defects. Risk factors for glaucoma noted. Patient also has borderline diabetes, chronic anemia and a family history of macular degeneration."}
{"question_id": 14, "question": "Does the patient suffer from chronic anemia?\n", "answer": "Yes.", "image": "slo_fundus_08009.jpg", "report": "Patient displays thin temporal os and hvf 24-2 shows corresponding inferior defects. Risk factors for glaucoma noted. Patient also has borderline diabetes, chronic anemia and a family history of macular degeneration."}
{"question_id": 15, "question": "Is there a family history of macular degeneration for this patient?\n", "answer": "Yes.", "image": "slo_fundus_08009.jpg", "report": "Patient displays thin temporal os and hvf 24-2 shows corresponding inferior defects. Risk factors for glaucoma noted. Patient also has borderline diabetes, chronic anemia and a family history of macular degeneration."}
{"question_id": 16, "question": "Does the patient suffer from dry eye?\n", "answer": "Yes.", "image": "slo_fundus_08010.jpg", "report": "The 44-year-old patient has dry eye, pinguecula, and optic disc cupping. There are nonspecific defects in their visual field, and thinning in the superior and temporal sectors of the eye. No signs of glaucoma."}
{"question_id": 17, "question": "Is there a pinguecula present in the patient's eye?\n", "answer": "Yes.", "image": "slo_fundus_08010.jpg", "report": "The 44-year-old patient has dry eye, pinguecula, and optic disc cupping. There are nonspecific defects in their visual field, and thinning in the superior and temporal sectors of the eye. No signs of glaucoma."}
{"question_id": 18, "question": "Does the patient exhibit optic disc cupping?\n", "answer": "Yes.", "image": "slo_fundus_08010.jpg", "report": "The 44-year-old patient has dry eye, pinguecula, and optic disc cupping. There are nonspecific defects in their visual field, and thinning in the superior and temporal sectors of the eye. No signs of glaucoma."}
{"question_id": 19, "question": "Are there nonspecific defects in the patient's visual field?\n", "answer": "Yes.", "image": "slo_fundus_08010.jpg", "report": "The 44-year-old patient has dry eye, pinguecula, and optic disc cupping. There are nonspecific defects in their visual field, and thinning in the superior and temporal sectors of the eye. No signs of glaucoma."}
{"question_id": 20, "question": "Is there thinning in the superior sector of the patient's eye?\n", "answer": "Yes.", "image": "slo_fundus_08010.jpg", "report": "The 44-year-old patient has dry eye, pinguecula, and optic disc cupping. There are nonspecific defects in their visual field, and thinning in the superior and temporal sectors of the eye. No signs of glaucoma."}
{"question_id": 21, "question": "Is there thinning in the temporal sector of the patient's eye?\n", "answer": "Yes.", "image": "slo_fundus_08010.jpg", "report": "The 44-year-old patient has dry eye, pinguecula, and optic disc cupping. There are nonspecific defects in their visual field, and thinning in the superior and temporal sectors of the eye. No signs of glaucoma."}
{"question_id": 22, "question": "Are there any signs of glaucoma in the patient's eye?\n", "answer": "No.", "image": "slo_fundus_08010.jpg", "report": "The 44-year-old patient has dry eye, pinguecula, and optic disc cupping. There are nonspecific defects in their visual field, and thinning in the superior and temporal sectors of the eye. No signs of glaucoma."}
{"question_id": 23, "question": "Is the patient dissatisfied with the visual outcome after glaucoma surgery?\n", "answer": "Yes.", "image": "slo_fundus_08013.jpg", "report": "Patient unhappy with post-surgery visual improvement due to severe glaucoma. Misunderstood pre-surgery conversations. Sought second opinion but decided to continue with current provider. Upcoming appointments scheduled for eyelid, cornea and low-vision care."}
{"question_id": 24, "question": "Did the patient have severe glaucoma prior to the surgery?\n", "answer": "Yes.", "image": "slo_fundus_08013.jpg", "report": "Patient unhappy with post-surgery visual improvement due to severe glaucoma. Misunderstood pre-surgery conversations. Sought second opinion but decided to continue with current provider. Upcoming appointments scheduled for eyelid, cornea and low-vision care."}
{"question_id": 25, "question": "Was there a misunderstanding in the pre-surgery conversations regarding the expected outcomes?\n", "answer": "Yes.", "image": "slo_fundus_08013.jpg", "report": "Patient unhappy with post-surgery visual improvement due to severe glaucoma. Misunderstood pre-surgery conversations. Sought second opinion but decided to continue with current provider. Upcoming appointments scheduled for eyelid, cornea and low-vision care."}
{"question_id": 26, "question": "Has the patient sought a second opinion regarding their post-surgery visual improvement?\n", "answer": "Yes.", "image": "slo_fundus_08013.jpg", "report": "Patient unhappy with post-surgery visual improvement due to severe glaucoma. Misunderstood pre-surgery conversations. Sought second opinion but decided to continue with current provider. Upcoming appointments scheduled for eyelid, cornea and low-vision care."}
{"question_id": 27, "question": "Despite seeking a second opinion, has the patient decided to continue care with the original provider?\n", "answer": "Yes.", "image": "slo_fundus_08013.jpg", "report": "Patient unhappy with post-surgery visual improvement due to severe glaucoma. Misunderstood pre-surgery conversations. Sought second opinion but decided to continue with current provider. Upcoming appointments scheduled for eyelid, cornea and low-vision care."}
{"question_id": 28, "question": "Are there upcoming appointments for the patient concerning eyelid care?\n", "answer": "Yes.", "image": "slo_fundus_08013.jpg", "report": "Patient unhappy with post-surgery visual improvement due to severe glaucoma. Misunderstood pre-surgery conversations. Sought second opinion but decided to continue with current provider. Upcoming appointments scheduled for eyelid, cornea and low-vision care."}
{"question_id": 29, "question": "Does the patient have a scheduled appointment for cornea care?\n", "answer": "Yes.", "image": "slo_fundus_08013.jpg", "report": "Patient unhappy with post-surgery visual improvement due to severe glaucoma. Misunderstood pre-surgery conversations. Sought second opinion but decided to continue with current provider. Upcoming appointments scheduled for eyelid, cornea and low-vision care."}
{"question_id": 30, "question": "Is the patient also scheduled for low-vision care services?\n", "answer": "Yes.", "image": "slo_fundus_08013.jpg", "report": "Patient unhappy with post-surgery visual improvement due to severe glaucoma. Misunderstood pre-surgery conversations. Sought second opinion but decided to continue with current provider. Upcoming appointments scheduled for eyelid, cornea and low-vision care."}
{"question_id": 31, "question": "Is the patient suspected of having open-angle glaucoma?\n", "answer": "Yes.", "image": "slo_fundus_08016.jpg", "report": "The patient, a 65-year-old female, is a suspect for open-angle glaucoma, presenting no family history. She also has sulfa allergy, a history of trauma, and early cataracts. For now, no glaucoma treatment is planned."}
{"question_id": 32, "question": "Does the patient have a known family history of glaucoma?\n", "answer": "No.", "image": "slo_fundus_08016.jpg", "report": "The patient, a 65-year-old female, is a suspect for open-angle glaucoma, presenting no family history. She also has sulfa allergy, a history of trauma, and early cataracts. For now, no glaucoma treatment is planned."}
{"question_id": 33, "question": "Does the patient have a sulfa allergy?\n", "answer": "Yes.", "image": "slo_fundus_08016.jpg", "report": "The patient, a 65-year-old female, is a suspect for open-angle glaucoma, presenting no family history. She also has sulfa allergy, a history of trauma, and early cataracts. For now, no glaucoma treatment is planned."}
{"question_id": 34, "question": "Has the patient experienced ocular trauma in the past?\n", "answer": "Yes.", "image": "slo_fundus_08016.jpg", "report": "The patient, a 65-year-old female, is a suspect for open-angle glaucoma, presenting no family history. She also has sulfa allergy, a history of trauma, and early cataracts. For now, no glaucoma treatment is planned."}
{"question_id": 35, "question": "Does the patient have early-stage cataracts?\n", "answer": "Yes.", "image": "slo_fundus_08016.jpg", "report": "The patient, a 65-year-old female, is a suspect for open-angle glaucoma, presenting no family history. She also has sulfa allergy, a history of trauma, and early cataracts. For now, no glaucoma treatment is planned."}
{"question_id": 36, "question": "Is the patient currently receiving treatment for glaucoma?\n", "answer": "No.", "image": "slo_fundus_08016.jpg", "report": "The patient, a 65-year-old female, is a suspect for open-angle glaucoma, presenting no family history. She also has sulfa allergy, a history of trauma, and early cataracts. For now, no glaucoma treatment is planned."}
{"question_id": 37, "question": "Is the patient currently using brimonidine/alphagan for the left eye?\n", "answer": "Yes.", "image": "slo_fundus_08019.jpg", "report": "Patient is on brimonidine/alphagan for the left eye 2x/day & prednisolone for the right eye 1x/day. Advised not to rub operated eye for 4 weeks. Urged to contact the glaucoma department for any concerns."}
{"question_id": 38, "question": "Is the patient prescribed to use prednisolone for the right eye once a day?\n", "answer": "Yes.", "image": "slo_fundus_08019.jpg", "report": "Patient is on brimonidine/alphagan for the left eye 2x/day & prednisolone for the right eye 1x/day. Advised not to rub operated eye for 4 weeks. Urged to contact the glaucoma department for any concerns."}
{"question_id": 39, "question": "Has the patient been advised to avoid rubbing the operated eye for 4 weeks?\n", "answer": "Yes.", "image": "slo_fundus_08019.jpg", "report": "Patient is on brimonidine/alphagan for the left eye 2x/day & prednisolone for the right eye 1x/day. Advised not to rub operated eye for 4 weeks. Urged to contact the glaucoma department for any concerns."}
{"question_id": 40, "question": "Should the patient contact the glaucoma department if they have any concerns?\n", "answer": "Yes.", "image": "slo_fundus_08019.jpg", "report": "Patient is on brimonidine/alphagan for the left eye 2x/day & prednisolone for the right eye 1x/day. Advised not to rub operated eye for 4 weeks. Urged to contact the glaucoma department for any concerns."}
{"question_id": 41, "question": "Does the patient have primary open-angle glaucoma in the left eye?\n", "answer": "Yes.", "image": "slo_fundus_08021.jpg", "report": "The patient, formerly of Pasquale, has primary open angle glaucoma and amblyopia in the left eye. Other issues include lattice in both eyes and a history of cataract extraction in both eyes."}
{"question_id": 42, "question": "Is the patient diagnosed with amblyopia in the left eye?\n", "answer": "Yes.", "image": "slo_fundus_08021.jpg", "report": "The patient, formerly of Pasquale, has primary open angle glaucoma and amblyopia in the left eye. Other issues include lattice in both eyes and a history of cataract extraction in both eyes."}
{"question_id": 43, "question": "Does the patient have lattice degeneration in both eyes?\n", "answer": "Yes.", "image": "slo_fundus_08021.jpg", "report": "The patient, formerly of Pasquale, has primary open angle glaucoma and amblyopia in the left eye. Other issues include lattice in both eyes and a history of cataract extraction in both eyes."}
{"question_id": 44, "question": "Has the patient undergone cataract extraction in both eyes?\n", "answer": "Yes.", "image": "slo_fundus_08021.jpg", "report": "The patient, formerly of Pasquale, has primary open angle glaucoma and amblyopia in the left eye. Other issues include lattice in both eyes and a history of cataract extraction in both eyes."}
{"question_id": 45, "question": "Has the patient been diagnosed with low tension glaucoma?\n", "answer": "Yes.", "image": "slo_fundus_08022.jpg", "report": "Patient visited for a second opinion and was diagnosed with low tension glaucoma. Initial visit showed no thinning in the right eye, but focal superior thinning in left eye. Plans to start new medication regimen including timoptic, brimonidine and continuing latanoprost. "}
{"question_id": 46, "question": "Was there any thinning observed in the right eye during the initial visit?\n", "answer": "No.", "image": "slo_fundus_08022.jpg", "report": "Patient visited for a second opinion and was diagnosed with low tension glaucoma. Initial visit showed no thinning in the right eye, but focal superior thinning in left eye. Plans to start new medication regimen including timoptic, brimonidine and continuing latanoprost. "}
{"question_id": 47, "question": "Was focal superior thinning observed in the left eye?\n", "answer": "Yes.", "image": "slo_fundus_08022.jpg", "report": "Patient visited for a second opinion and was diagnosed with low tension glaucoma. Initial visit showed no thinning in the right eye, but focal superior thinning in left eye. Plans to start new medication regimen including timoptic, brimonidine and continuing latanoprost. "}
{"question_id": 48, "question": "Is the patient planned to start a new medication regimen that includes timoptic?\n", "answer": "Yes.", "image": "slo_fundus_08022.jpg", "report": "Patient visited for a second opinion and was diagnosed with low tension glaucoma. Initial visit showed no thinning in the right eye, but focal superior thinning in left eye. Plans to start new medication regimen including timoptic, brimonidine and continuing latanoprost. "}
{"question_id": 49, "question": "Is brimonidine part of the new medication regimen for the patient?\n", "answer": "Yes.", "image": "slo_fundus_08022.jpg", "report": "Patient visited for a second opinion and was diagnosed with low tension glaucoma. Initial visit showed no thinning in the right eye, but focal superior thinning in left eye. Plans to start new medication regimen including timoptic, brimonidine and continuing latanoprost. "}
{"question_id": 50, "question": "Will the patient continue using latanoprost as part of their treatment?\n", "answer": "Yes.", "image": "slo_fundus_08022.jpg", "report": "Patient visited for a second opinion and was diagnosed with low tension glaucoma. Initial visit showed no thinning in the right eye, but focal superior thinning in left eye. Plans to start new medication regimen including timoptic, brimonidine and continuing latanoprost. "}
{"question_id": 51, "question": "Has the patient been diagnosed with glaucoma?\n", "answer": "No.", "image": "slo_fundus_08024.jpg", "report": "61 y.o. white, non-hispanic male with no diagnosis of glaucoma. Requested to mail clinical note to specific person and location."}
{"question_id": 52, "question": "Did the patient request to mail the clinical note to a specific person and location?\n", "answer": "Yes.", "image": "slo_fundus_08024.jpg", "report": "61 y.o. white, non-hispanic male with no diagnosis of glaucoma. Requested to mail clinical note to specific person and location."}
{"question_id": 53, "question": "Is the patient suspected to have glaucoma due to family history and ocular hypertension?\n", "answer": "Yes.", "image": "slo_fundus_08032.jpg", "report": "61 y.o. male suspect for glaucoma due to family history, ocular hypertension, and high intraocular pressure (IOP: 29/32). His father possibly had glaucoma. Patient also has incipient senile cataract, myopia, astigmatism, and presbyopia."}
{"question_id": 54, "question": "Was the patient's intraocular pressure found to be high, with readings of 29 in one eye and 32 in the other?\n", "answer": "Yes.", "image": "slo_fundus_08032.jpg", "report": "61 y.o. male suspect for glaucoma due to family history, ocular hypertension, and high intraocular pressure (IOP: 29/32). His father possibly had glaucoma. Patient also has incipient senile cataract, myopia, astigmatism, and presbyopia."}
{"question_id": 55, "question": "Did the patient's father possibly have glaucoma?\n", "answer": "Yes.", "image": "slo_fundus_08032.jpg", "report": "61 y.o. male suspect for glaucoma due to family history, ocular hypertension, and high intraocular pressure (IOP: 29/32). His father possibly had glaucoma. Patient also has incipient senile cataract, myopia, astigmatism, and presbyopia."}
{"question_id": 56, "question": "Does the patient have an incipient senile cataract?\n", "answer": "Yes.", "image": "slo_fundus_08032.jpg", "report": "61 y.o. male suspect for glaucoma due to family history, ocular hypertension, and high intraocular pressure (IOP: 29/32). His father possibly had glaucoma. Patient also has incipient senile cataract, myopia, astigmatism, and presbyopia."}
{"question_id": 57, "question": "Is the patient myopic?\n", "answer": "Yes.", "image": "slo_fundus_08032.jpg", "report": "61 y.o. male suspect for glaucoma due to family history, ocular hypertension, and high intraocular pressure (IOP: 29/32). His father possibly had glaucoma. Patient also has incipient senile cataract, myopia, astigmatism, and presbyopia."}
{"question_id": 58, "question": "Does the patient have astigmatism?\n", "answer": "Yes.", "image": "slo_fundus_08032.jpg", "report": "61 y.o. male suspect for glaucoma due to family history, ocular hypertension, and high intraocular pressure (IOP: 29/32). His father possibly had glaucoma. Patient also has incipient senile cataract, myopia, astigmatism, and presbyopia."}
{"question_id": 59, "question": "Is the patient presbyopic?\n", "answer": "Yes.", "image": "slo_fundus_08032.jpg", "report": "61 y.o. male suspect for glaucoma due to family history, ocular hypertension, and high intraocular pressure (IOP: 29/32). His father possibly had glaucoma. Patient also has incipient senile cataract, myopia, astigmatism, and presbyopia."}
{"question_id": 60, "question": "Does the patient have a visually significant cataract?\n", "answer": "Yes.", "image": "slo_fundus_08035.jpg", "report": "76yo patient has depression, htn, breast cancer, visually significant cataract, pseudophakia os, and glaucoma (recently diagnosed, on latanoprost). No family history of glaucoma. IOP is OK but concern about hvf defect. Also has allergic conjunctivitis, and conjunctival pigment."}
{"question_id": 61, "question": "Is the patient pseudophakic in the left eye?\n", "answer": "Yes.", "image": "slo_fundus_08035.jpg", "report": "76yo patient has depression, htn, breast cancer, visually significant cataract, pseudophakia os, and glaucoma (recently diagnosed, on latanoprost). No family history of glaucoma. IOP is OK but concern about hvf defect. Also has allergic conjunctivitis, and conjunctival pigment."}
{"question_id": 62, "question": "Has the patient been recently diagnosed with glaucoma?\n", "answer": "Yes.", "image": "slo_fundus_08035.jpg", "report": "76yo patient has depression, htn, breast cancer, visually significant cataract, pseudophakia os, and glaucoma (recently diagnosed, on latanoprost). No family history of glaucoma. IOP is OK but concern about hvf defect. Also has allergic conjunctivitis, and conjunctival pigment."}
{"question_id": 63, "question": "Is the patient currently being treated with latanoprost for glaucoma?\n", "answer": "Yes.", "image": "slo_fundus_08035.jpg", "report": "76yo patient has depression, htn, breast cancer, visually significant cataract, pseudophakia os, and glaucoma (recently diagnosed, on latanoprost). No family history of glaucoma. IOP is OK but concern about hvf defect. Also has allergic conjunctivitis, and conjunctival pigment."}
{"question_id": 64, "question": "Is the intraocular pressure (IOP) of the patient currently within normal limits?\n", "answer": "Yes.", "image": "slo_fundus_08035.jpg", "report": "76yo patient has depression, htn, breast cancer, visually significant cataract, pseudophakia os, and glaucoma (recently diagnosed, on latanoprost). No family history of glaucoma. IOP is OK but concern about hvf defect. Also has allergic conjunctivitis, and conjunctival pigment."}
{"question_id": 65, "question": "Is there a concern about a visual field (HVF) defect in the patient?\n", "answer": "Yes.", "image": "slo_fundus_08035.jpg", "report": "76yo patient has depression, htn, breast cancer, visually significant cataract, pseudophakia os, and glaucoma (recently diagnosed, on latanoprost). No family history of glaucoma. IOP is OK but concern about hvf defect. Also has allergic conjunctivitis, and conjunctival pigment."}
{"question_id": 66, "question": "Does the patient suffer from allergic conjunctivitis?\n", "answer": "Yes.", "image": "slo_fundus_08035.jpg", "report": "76yo patient has depression, htn, breast cancer, visually significant cataract, pseudophakia os, and glaucoma (recently diagnosed, on latanoprost). No family history of glaucoma. IOP is OK but concern about hvf defect. Also has allergic conjunctivitis, and conjunctival pigment."}
{"question_id": 67, "question": "Is there conjunctival pigment present in the patient's eye(s)?\n", "answer": "Yes.", "image": "slo_fundus_08035.jpg", "report": "76yo patient has depression, htn, breast cancer, visually significant cataract, pseudophakia os, and glaucoma (recently diagnosed, on latanoprost). No family history of glaucoma. IOP is OK but concern about hvf defect. Also has allergic conjunctivitis, and conjunctival pigment."}
{"question_id": 68, "question": "Does the patient have a family history of glaucoma?\n", "answer": "No.", "image": "slo_fundus_08035.jpg", "report": "76yo patient has depression, htn, breast cancer, visually significant cataract, pseudophakia os, and glaucoma (recently diagnosed, on latanoprost). No family history of glaucoma. IOP is OK but concern about hvf defect. Also has allergic conjunctivitis, and conjunctival pigment."}
{"question_id": 69, "question": "Does the patient have blepharitis?\n", "answer": "Yes.", "image": "slo_fundus_08040.jpg", "report": "The note discusses a 62-year-old female with blepharitis, who experiences significant improvement with ocusoft wipes. She wears multifocal contact lenses and is being referred to optometry. She is suspected of having glaucoma due to an increased c/d ratio, despite normal intraocular pressure. Other factors like family history or steroid medication use are ruled out. Eye scans reveal borderline changes and thinning superiorly. Future visits are scheduled for ongoing evaluation."}
{"question_id": 70, "question": "Has the patient experienced significant improvement with ocusoft wipes?\n", "answer": "Yes.", "image": "slo_fundus_08040.jpg", "report": "The note discusses a 62-year-old female with blepharitis, who experiences significant improvement with ocusoft wipes. She wears multifocal contact lenses and is being referred to optometry. She is suspected of having glaucoma due to an increased c/d ratio, despite normal intraocular pressure. Other factors like family history or steroid medication use are ruled out. Eye scans reveal borderline changes and thinning superiorly. Future visits are scheduled for ongoing evaluation."}
{"question_id": 71, "question": "Does the patient wear multifocal contact lenses?\n", "answer": "Yes.", "image": "slo_fundus_08040.jpg", "report": "The note discusses a 62-year-old female with blepharitis, who experiences significant improvement with ocusoft wipes. She wears multifocal contact lenses and is being referred to optometry. She is suspected of having glaucoma due to an increased c/d ratio, despite normal intraocular pressure. Other factors like family history or steroid medication use are ruled out. Eye scans reveal borderline changes and thinning superiorly. Future visits are scheduled for ongoing evaluation."}
{"question_id": 72, "question": "Is the patient being referred to optometry?\n", "answer": "Yes.", "image": "slo_fundus_08040.jpg", "report": "The note discusses a 62-year-old female with blepharitis, who experiences significant improvement with ocusoft wipes. She wears multifocal contact lenses and is being referred to optometry. She is suspected of having glaucoma due to an increased c/d ratio, despite normal intraocular pressure. Other factors like family history or steroid medication use are ruled out. Eye scans reveal borderline changes and thinning superiorly. Future visits are scheduled for ongoing evaluation."}
{"question_id": 73, "question": "Is the patient suspected of having glaucoma?\n", "answer": "Yes.", "image": "slo_fundus_08040.jpg", "report": "The note discusses a 62-year-old female with blepharitis, who experiences significant improvement with ocusoft wipes. She wears multifocal contact lenses and is being referred to optometry. She is suspected of having glaucoma due to an increased c/d ratio, despite normal intraocular pressure. Other factors like family history or steroid medication use are ruled out. Eye scans reveal borderline changes and thinning superiorly. Future visits are scheduled for ongoing evaluation."}
{"question_id": 74, "question": "Is the increased c/d ratio the reason for the glaucoma suspicion?\n", "answer": "Yes.", "image": "slo_fundus_08040.jpg", "report": "The note discusses a 62-year-old female with blepharitis, who experiences significant improvement with ocusoft wipes. She wears multifocal contact lenses and is being referred to optometry. She is suspected of having glaucoma due to an increased c/d ratio, despite normal intraocular pressure. Other factors like family history or steroid medication use are ruled out. Eye scans reveal borderline changes and thinning superiorly. Future visits are scheduled for ongoing evaluation."}
{"question_id": 75, "question": "Does the patient have normal intraocular pressure despite the glaucoma suspicion?\n", "answer": "Yes.", "image": "slo_fundus_08040.jpg", "report": "The note discusses a 62-year-old female with blepharitis, who experiences significant improvement with ocusoft wipes. She wears multifocal contact lenses and is being referred to optometry. She is suspected of having glaucoma due to an increased c/d ratio, despite normal intraocular pressure. Other factors like family history or steroid medication use are ruled out. Eye scans reveal borderline changes and thinning superiorly. Future visits are scheduled for ongoing evaluation."}
{"question_id": 76, "question": "Have family history and steroid medication use been ruled out as factors for glaucoma in this patient?\n", "answer": "Yes.", "image": "slo_fundus_08040.jpg", "report": "The note discusses a 62-year-old female with blepharitis, who experiences significant improvement with ocusoft wipes. She wears multifocal contact lenses and is being referred to optometry. She is suspected of having glaucoma due to an increased c/d ratio, despite normal intraocular pressure. Other factors like family history or steroid medication use are ruled out. Eye scans reveal borderline changes and thinning superiorly. Future visits are scheduled for ongoing evaluation."}
{"question_id": 77, "question": "Do the eye scans reveal borderline changes?\n", "answer": "Yes.", "image": "slo_fundus_08040.jpg", "report": "The note discusses a 62-year-old female with blepharitis, who experiences significant improvement with ocusoft wipes. She wears multifocal contact lenses and is being referred to optometry. She is suspected of having glaucoma due to an increased c/d ratio, despite normal intraocular pressure. Other factors like family history or steroid medication use are ruled out. Eye scans reveal borderline changes and thinning superiorly. Future visits are scheduled for ongoing evaluation."}
{"question_id": 78, "question": "Is there thinning observed superiorly on the eye scans?\n", "answer": "Yes.", "image": "slo_fundus_08040.jpg", "report": "The note discusses a 62-year-old female with blepharitis, who experiences significant improvement with ocusoft wipes. She wears multifocal contact lenses and is being referred to optometry. She is suspected of having glaucoma due to an increased c/d ratio, despite normal intraocular pressure. Other factors like family history or steroid medication use are ruled out. Eye scans reveal borderline changes and thinning superiorly. Future visits are scheduled for ongoing evaluation."}
{"question_id": 79, "question": "Are future visits scheduled for ongoing evaluation of the patient's eye condition?\n", "answer": "Yes.", "image": "slo_fundus_08040.jpg", "report": "The note discusses a 62-year-old female with blepharitis, who experiences significant improvement with ocusoft wipes. She wears multifocal contact lenses and is being referred to optometry. She is suspected of having glaucoma due to an increased c/d ratio, despite normal intraocular pressure. Other factors like family history or steroid medication use are ruled out. Eye scans reveal borderline changes and thinning superiorly. Future visits are scheduled for ongoing evaluation."}
{"question_id": 80, "question": "Does the patient show signs of glaucoma?\n", "answer": "Yes.", "image": "slo_fundus_08047.jpg", "report": "Patient shows signs of glaucoma. Hx of amblyopia in left eye. No HIV retinopathy. Marked cupping OD>OS. Intraocular pressure highly elevated. RNFL thinning OD. Normal HVF."}
{"question_id": 81, "question": "Does the patient have a history of amblyopia in the left eye?\n", "answer": "Yes.", "image": "slo_fundus_08047.jpg", "report": "Patient shows signs of glaucoma. Hx of amblyopia in left eye. No HIV retinopathy. Marked cupping OD>OS. Intraocular pressure highly elevated. RNFL thinning OD. Normal HVF."}
{"question_id": 82, "question": "Is there any indication of HIV retinopathy in the fundus images?\n", "answer": "No.", "image": "slo_fundus_08047.jpg", "report": "Patient shows signs of glaucoma. Hx of amblyopia in left eye. No HIV retinopathy. Marked cupping OD>OS. Intraocular pressure highly elevated. RNFL thinning OD. Normal HVF."}
{"question_id": 83, "question": "Is there marked cupping observed in the right eye greater than the left eye?\n", "answer": "Yes.", "image": "slo_fundus_08047.jpg", "report": "Patient shows signs of glaucoma. Hx of amblyopia in left eye. No HIV retinopathy. Marked cupping OD>OS. Intraocular pressure highly elevated. RNFL thinning OD. Normal HVF."}
{"question_id": 84, "question": "Is the intraocular pressure highly elevated in the patient's eyes?\n", "answer": "Yes.", "image": "slo_fundus_08047.jpg", "report": "Patient shows signs of glaucoma. Hx of amblyopia in left eye. No HIV retinopathy. Marked cupping OD>OS. Intraocular pressure highly elevated. RNFL thinning OD. Normal HVF."}
{"question_id": 85, "question": "Is there retinal nerve fiber layer (RNFL) thinning in the right eye (OD)?\n", "answer": "Yes.", "image": "slo_fundus_08047.jpg", "report": "Patient shows signs of glaucoma. Hx of amblyopia in left eye. No HIV retinopathy. Marked cupping OD>OS. Intraocular pressure highly elevated. RNFL thinning OD. Normal HVF."}
{"question_id": 86, "question": "Are the results of the Humphrey Visual Field (HVF) test normal?\n", "answer": "Yes.", "image": "slo_fundus_08047.jpg", "report": "Patient shows signs of glaucoma. Hx of amblyopia in left eye. No HIV retinopathy. Marked cupping OD>OS. Intraocular pressure highly elevated. RNFL thinning OD. Normal HVF."}
{"question_id": 87, "question": "Does the patient have presbyopia?\n", "answer": "Yes.", "image": "slo_fundus_08050.jpg", "report": "Patient has presbyopia and glaucoma. Undergoing treatment to control intraocular pressure (IOP). Recent procedures include phaco/xen gel stent. Plans to possibly continue with phaco/xen procedure on next visit."}
{"question_id": 88, "question": "Does the patient have glaucoma?\n", "answer": "Yes.", "image": "slo_fundus_08050.jpg", "report": "Patient has presbyopia and glaucoma. Undergoing treatment to control intraocular pressure (IOP). Recent procedures include phaco/xen gel stent. Plans to possibly continue with phaco/xen procedure on next visit."}
{"question_id": 89, "question": "Is the patient currently undergoing treatment to control intraocular pressure?\n", "answer": "Yes.", "image": "slo_fundus_08050.jpg", "report": "Patient has presbyopia and glaucoma. Undergoing treatment to control intraocular pressure (IOP). Recent procedures include phaco/xen gel stent. Plans to possibly continue with phaco/xen procedure on next visit."}
{"question_id": 90, "question": "Has the patient recently undergone a phaco/xen gel stent procedure?\n", "answer": "Yes.", "image": "slo_fundus_08050.jpg", "report": "Patient has presbyopia and glaucoma. Undergoing treatment to control intraocular pressure (IOP). Recent procedures include phaco/xen gel stent. Plans to possibly continue with phaco/xen procedure on next visit."}
{"question_id": 91, "question": "Is there a possibility of continuing with a phaco/xen procedure in the next visit?\n", "answer": "Yes.", "image": "slo_fundus_08050.jpg", "report": "Patient has presbyopia and glaucoma. Undergoing treatment to control intraocular pressure (IOP). Recent procedures include phaco/xen gel stent. Plans to possibly continue with phaco/xen procedure on next visit."}
{"question_id": 92, "question": "Is the intraocular pressure currently measured at 16 in both eyes?\n", "answer": "Yes.", "image": "slo_fundus_08054.jpg", "report": "Patient, 68, with GERD, hypertension, intraocular pressure is 16/16, previously was 18/17, 26/23, max of 26/23. Patient has ocular hypertension. C/D ratio is 0.5/0.5, open on gonioscopy. No mention of glaucoma."}
{"question_id": 93, "question": "Has the patient's intraocular pressure previously been recorded at higher values such as 26/23?\n", "answer": "Yes.", "image": "slo_fundus_08054.jpg", "report": "Patient, 68, with GERD, hypertension, intraocular pressure is 16/16, previously was 18/17, 26/23, max of 26/23. Patient has ocular hypertension. C/D ratio is 0.5/0.5, open on gonioscopy. No mention of glaucoma."}
{"question_id": 94, "question": "Is the patient diagnosed with ocular hypertension?\n", "answer": "Yes.", "image": "slo_fundus_08054.jpg", "report": "Patient, 68, with GERD, hypertension, intraocular pressure is 16/16, previously was 18/17, 26/23, max of 26/23. Patient has ocular hypertension. C/D ratio is 0.5/0.5, open on gonioscopy. No mention of glaucoma."}
{"question_id": 95, "question": "Is the cup-to-disc (C/D) ratio 0.5 in both eyes?\n", "answer": "Yes.", "image": "slo_fundus_08054.jpg", "report": "Patient, 68, with GERD, hypertension, intraocular pressure is 16/16, previously was 18/17, 26/23, max of 26/23. Patient has ocular hypertension. C/D ratio is 0.5/0.5, open on gonioscopy. No mention of glaucoma."}
{"question_id": 96, "question": "Were the angles found to be open on gonioscopy?\n", "answer": "Yes.", "image": "slo_fundus_08054.jpg", "report": "Patient, 68, with GERD, hypertension, intraocular pressure is 16/16, previously was 18/17, 26/23, max of 26/23. Patient has ocular hypertension. C/D ratio is 0.5/0.5, open on gonioscopy. No mention of glaucoma."}
{"question_id": 97, "question": "Is there any mention of glaucoma in the patient's summary?\n", "answer": "No.", "image": "slo_fundus_08054.jpg", "report": "Patient, 68, with GERD, hypertension, intraocular pressure is 16/16, previously was 18/17, 26/23, max of 26/23. Patient has ocular hypertension. C/D ratio is 0.5/0.5, open on gonioscopy. No mention of glaucoma."}
{"question_id": 98, "question": "Does the patient have glaucoma?\n", "answer": "Yes.", "image": "slo_fundus_08055.jpg", "report": "The patient has glaucoma and is considering different types of surgery. Due to the severe irritation caused by current medication, they proceeded with phaco/trab mmc os. Follow-up planned for IOP check."}
{"question_id": 99, "question": "Is the patient considering surgery options for their condition?\n", "answer": "Yes.", "image": "slo_fundus_08055.jpg", "report": "The patient has glaucoma and is considering different types of surgery. Due to the severe irritation caused by current medication, they proceeded with phaco/trab mmc os. Follow-up planned for IOP check."}
{"question_id": 100, "question": "Has the patient experienced severe irritation from the current medication?\n", "answer": "Yes.", "image": "slo_fundus_08055.jpg", "report": "The patient has glaucoma and is considering different types of surgery. Due to the severe irritation caused by current medication, they proceeded with phaco/trab mmc os. Follow-up planned for IOP check."}
{"question_id": 101, "question": "Did the patient undergo a phaco/trab mmc os procedure?\n", "answer": "Yes.", "image": "slo_fundus_08055.jpg", "report": "The patient has glaucoma and is considering different types of surgery. Due to the severe irritation caused by current medication, they proceeded with phaco/trab mmc os. Follow-up planned for IOP check."}
{"question_id": 102, "question": "Is a follow-up planned specifically for an intraocular pressure (IOP) check?\n", "answer": "Yes.", "image": "slo_fundus_08055.jpg", "report": "The patient has glaucoma and is considering different types of surgery. Due to the severe irritation caused by current medication, they proceeded with phaco/trab mmc os. Follow-up planned for IOP check."}
{"question_id": 103, "question": "Is a visual field test scheduled to be performed on the left eye?\n", "answer": "Yes.", "image": "slo_fundus_08056.jpg", "report": "Visual field test is to be performed on the left eye with lid taping, following monocular precautions. No mention of glaucoma."}
{"question_id": 104, "question": "Is lid taping going to be used during the visual field test?\n", "answer": "Yes.", "image": "slo_fundus_08056.jpg", "report": "Visual field test is to be performed on the left eye with lid taping, following monocular precautions. No mention of glaucoma."}
{"question_id": 105, "question": "Are monocular precautions to be observed during the visual field test?\n", "answer": "Yes.", "image": "slo_fundus_08056.jpg", "report": "Visual field test is to be performed on the left eye with lid taping, following monocular precautions. No mention of glaucoma."}
{"question_id": 106, "question": "Is glaucoma mentioned in relation to the patient's condition?\n", "answer": "No.", "image": "slo_fundus_08056.jpg", "report": "Visual field test is to be performed on the left eye with lid taping, following monocular precautions. No mention of glaucoma."}
{"question_id": 107, "question": "Does the patient have a suspected myelinated nerve fiber layer in the right eye (OD)?\n", "answer": "Yes.", "image": "slo_fundus_08057.jpg", "report": "Patient has suspected myelinated nerve fiber layer od, near circumferential on exam. Experiencing enlarging blind spot; advised to bring records to next appointment. No mention of glaucoma."}
{"question_id": 108, "question": "Is the myelinated nerve fiber layer nearly circumferential upon examination?\n", "answer": "Yes.", "image": "slo_fundus_08057.jpg", "report": "Patient has suspected myelinated nerve fiber layer od, near circumferential on exam. Experiencing enlarging blind spot; advised to bring records to next appointment. No mention of glaucoma."}
{"question_id": 109, "question": "Is the patient experiencing an enlarging blind spot?\n", "answer": "Yes.", "image": "slo_fundus_08057.jpg", "report": "Patient has suspected myelinated nerve fiber layer od, near circumferential on exam. Experiencing enlarging blind spot; advised to bring records to next appointment. No mention of glaucoma."}
{"question_id": 110, "question": "Has glaucoma been mentioned in the patient's summary?\n", "answer": "No.", "image": "slo_fundus_08057.jpg", "report": "Patient has suspected myelinated nerve fiber layer od, near circumferential on exam. Experiencing enlarging blind spot; advised to bring records to next appointment. No mention of glaucoma."}
{"question_id": 111, "question": "Was the patient advised to bring records to the next appointment?\n", "answer": "Yes.", "image": "slo_fundus_08057.jpg", "report": "Patient has suspected myelinated nerve fiber layer od, near circumferential on exam. Experiencing enlarging blind spot; advised to bring records to next appointment. No mention of glaucoma."}
{"question_id": 112, "question": "Does the patient have glaucoma?\n", "answer": "Yes.", "image": "slo_fundus_08058.jpg", "report": "The patient has glaucoma and is taking multiple medications: Timolol/Brimonidine 1x/night in both eyes, Dorzolamide 3x/day in right eye, Netarsudil 1x/night in right eye, and artificial tears as needed in both eyes."}
{"question_id": 113, "question": "Is the patient currently using Timolol/Brimonidine combination drops once a night in both eyes?\n", "answer": "Yes.", "image": "slo_fundus_08058.jpg", "report": "The patient has glaucoma and is taking multiple medications: Timolol/Brimonidine 1x/night in both eyes, Dorzolamide 3x/day in right eye, Netarsudil 1x/night in right eye, and artificial tears as needed in both eyes."}
{"question_id": 114, "question": "Is Dorzolamide being administered three times a day in the patient's right eye?\n", "answer": "Yes.", "image": "slo_fundus_08058.jpg", "report": "The patient has glaucoma and is taking multiple medications: Timolol/Brimonidine 1x/night in both eyes, Dorzolamide 3x/day in right eye, Netarsudil 1x/night in right eye, and artificial tears as needed in both eyes."}
{"question_id": 115, "question": "Is Netarsudil part of the patient's medication regimen, applied once nightly in the right eye?\n", "answer": "Yes.", "image": "slo_fundus_08058.jpg", "report": "The patient has glaucoma and is taking multiple medications: Timolol/Brimonidine 1x/night in both eyes, Dorzolamide 3x/day in right eye, Netarsudil 1x/night in right eye, and artificial tears as needed in both eyes."}
{"question_id": 116, "question": "Are artificial tears being used by the patient as needed for both eyes?\n", "answer": "Yes.", "image": "slo_fundus_08058.jpg", "report": "The patient has glaucoma and is taking multiple medications: Timolol/Brimonidine 1x/night in both eyes, Dorzolamide 3x/day in right eye, Netarsudil 1x/night in right eye, and artificial tears as needed in both eyes."}
{"question_id": 117, "question": "Does the patient suffer from dry eyes?\n", "answer": "Yes.", "image": "slo_fundus_08066.jpg", "report": "69 y.o. male has dry eyes, blepharitis, ocular hypertension, cataracts (not visually significant), refractive error. No glaucoma detected. Monitoring for now."}
{"question_id": 118, "question": "Is blepharitis present in the patient's eye condition?\n", "answer": "Yes.", "image": "slo_fundus_08066.jpg", "report": "69 y.o. male has dry eyes, blepharitis, ocular hypertension, cataracts (not visually significant), refractive error. No glaucoma detected. Monitoring for now."}
{"question_id": 119, "question": "Has the patient been diagnosed with ocular hypertension?\n", "answer": "Yes.", "image": "slo_fundus_08066.jpg", "report": "69 y.o. male has dry eyes, blepharitis, ocular hypertension, cataracts (not visually significant), refractive error. No glaucoma detected. Monitoring for now."}
{"question_id": 120, "question": "Does the patient have cataracts that are not visually significant?\n", "answer": "Yes.", "image": "slo_fundus_08066.jpg", "report": "69 y.o. male has dry eyes, blepharitis, ocular hypertension, cataracts (not visually significant), refractive error. No glaucoma detected. Monitoring for now."}
{"question_id": 121, "question": "Is there a refractive error identified in the patient's eyes?\n", "answer": "Yes.", "image": "slo_fundus_08066.jpg", "report": "69 y.o. male has dry eyes, blepharitis, ocular hypertension, cataracts (not visually significant), refractive error. No glaucoma detected. Monitoring for now."}
{"question_id": 122, "question": "Has glaucoma been detected in this patient?\n", "answer": "No.", "image": "slo_fundus_08066.jpg", "report": "69 y.o. male has dry eyes, blepharitis, ocular hypertension, cataracts (not visually significant), refractive error. No glaucoma detected. Monitoring for now."}
{"question_id": 123, "question": "Is the current approach to the patient's eye condition to monitor the symptoms for now?\n", "answer": "Yes.", "image": "slo_fundus_08066.jpg", "report": "69 y.o. male has dry eyes, blepharitis, ocular hypertension, cataracts (not visually significant), refractive error. No glaucoma detected. Monitoring for now."}
{"question_id": 124, "question": "Is the patient considered a glaucoma suspect?\n", "answer": "Yes.", "image": "slo_fundus_08068.jpg", "report": "Patient is a glaucoma suspect, with myopia being a risk factor. Intraocular pressure is within normal range, with possible mild corneal arcus. New prescription for myopia with astigmatism and presbyopia given. The patient also has cataracts and borderline high cholesterol."}
{"question_id": 125, "question": "Is myopia a risk factor for the patient's glaucoma suspicion?\n", "answer": "Yes.", "image": "slo_fundus_08068.jpg", "report": "Patient is a glaucoma suspect, with myopia being a risk factor. Intraocular pressure is within normal range, with possible mild corneal arcus. New prescription for myopia with astigmatism and presbyopia given. The patient also has cataracts and borderline high cholesterol."}
{"question_id": 126, "question": "Is the intraocular pressure within the normal range for this patient?\n", "answer": "Yes.", "image": "slo_fundus_08068.jpg", "report": "Patient is a glaucoma suspect, with myopia being a risk factor. Intraocular pressure is within normal range, with possible mild corneal arcus. New prescription for myopia with astigmatism and presbyopia given. The patient also has cataracts and borderline high cholesterol."}
{"question_id": 127, "question": "Does the patient show signs of a possible mild corneal arcus?\n", "answer": "Yes.", "image": "slo_fundus_08068.jpg", "report": "Patient is a glaucoma suspect, with myopia being a risk factor. Intraocular pressure is within normal range, with possible mild corneal arcus. New prescription for myopia with astigmatism and presbyopia given. The patient also has cataracts and borderline high cholesterol."}
{"question_id": 128, "question": "Has the patient been given a new prescription that includes correction for myopia, astigmatism, and presbyopia?\n", "answer": "Yes.", "image": "slo_fundus_08068.jpg", "report": "Patient is a glaucoma suspect, with myopia being a risk factor. Intraocular pressure is within normal range, with possible mild corneal arcus. New prescription for myopia with astigmatism and presbyopia given. The patient also has cataracts and borderline high cholesterol."}
{"question_id": 129, "question": "Does the patient have cataracts?\n", "answer": "Yes.", "image": "slo_fundus_08068.jpg", "report": "Patient is a glaucoma suspect, with myopia being a risk factor. Intraocular pressure is within normal range, with possible mild corneal arcus. New prescription for myopia with astigmatism and presbyopia given. The patient also has cataracts and borderline high cholesterol."}
{"question_id": 130, "question": "Does the patient have borderline high cholesterol?\n", "answer": "Yes.", "image": "slo_fundus_08068.jpg", "report": "Patient is a glaucoma suspect, with myopia being a risk factor. Intraocular pressure is within normal range, with possible mild corneal arcus. New prescription for myopia with astigmatism and presbyopia given. The patient also has cataracts and borderline high cholesterol."}
{"question_id": 131, "question": "Is the patient seeking a second opinion for eye issues?\n", "answer": "Yes.", "image": "slo_fundus_08073.jpg", "report": "Patient seeking second opinion for eye issues. Goals include reducing intraocular pressure in both eyes. Glaucoma suspected due to elevated intraocular pressure. Current treatment includes Zioptan and PERSON medication and Xen Gel Stent procedure."}
{"question_id": 132, "question": "Are the goals of the patient to reduce intraocular pressure in both eyes?\n", "answer": "Yes.", "image": "slo_fundus_08073.jpg", "report": "Patient seeking second opinion for eye issues. Goals include reducing intraocular pressure in both eyes. Glaucoma suspected due to elevated intraocular pressure. Current treatment includes Zioptan and PERSON medication and Xen Gel Stent procedure."}
{"question_id": 133, "question": "Is glaucoma suspected in this patient due to elevated intraocular pressure?\n", "answer": "Yes.", "image": "slo_fundus_08073.jpg", "report": "Patient seeking second opinion for eye issues. Goals include reducing intraocular pressure in both eyes. Glaucoma suspected due to elevated intraocular pressure. Current treatment includes Zioptan and PERSON medication and Xen Gel Stent procedure."}
{"question_id": 134, "question": "Is the patient currently being treated with Zioptan?\n", "answer": "Yes.", "image": "slo_fundus_08073.jpg", "report": "Patient seeking second opinion for eye issues. Goals include reducing intraocular pressure in both eyes. Glaucoma suspected due to elevated intraocular pressure. Current treatment includes Zioptan and PERSON medication and Xen Gel Stent procedure."}
{"question_id": 135, "question": "Is PERSON medication part of the patient's current treatment regimen?\n", "answer": "Yes.", "image": "slo_fundus_08073.jpg", "report": "Patient seeking second opinion for eye issues. Goals include reducing intraocular pressure in both eyes. Glaucoma suspected due to elevated intraocular pressure. Current treatment includes Zioptan and PERSON medication and Xen Gel Stent procedure."}
{"question_id": 136, "question": "Has the patient undergone a Xen Gel Stent procedure?\n", "answer": "Yes.", "image": "slo_fundus_08073.jpg", "report": "Patient seeking second opinion for eye issues. Goals include reducing intraocular pressure in both eyes. Glaucoma suspected due to elevated intraocular pressure. Current treatment includes Zioptan and PERSON medication and Xen Gel Stent procedure."}
{"question_id": 137, "question": "Does the patient show signs of cupping that may suggest glaucoma?\n", "answer": "Yes.", "image": "slo_fundus_08075.jpg", "report": "Patient suspected of glaucoma due to cupping, has myopic astigmatism, Type 1 diabetes without retinopathy, and scheduled for silent sinus syndrome surgery."}
{"question_id": 138, "question": "Does the patient have myopic astigmatism?\n", "answer": "Yes.", "image": "slo_fundus_08075.jpg", "report": "Patient suspected of glaucoma due to cupping, has myopic astigmatism, Type 1 diabetes without retinopathy, and scheduled for silent sinus syndrome surgery."}
{"question_id": 139, "question": "Is the patient diagnosed with Type 1 diabetes?\n", "answer": "Yes.", "image": "slo_fundus_08075.jpg", "report": "Patient suspected of glaucoma due to cupping, has myopic astigmatism, Type 1 diabetes without retinopathy, and scheduled for silent sinus syndrome surgery."}
{"question_id": 140, "question": "Does the patient have diabetic retinopathy?\n", "answer": "No.", "image": "slo_fundus_08075.jpg", "report": "Patient suspected of glaucoma due to cupping, has myopic astigmatism, Type 1 diabetes without retinopathy, and scheduled for silent sinus syndrome surgery."}
{"question_id": 141, "question": "Is the patient scheduled to undergo surgery for silent sinus syndrome?\n", "answer": "Yes.", "image": "slo_fundus_08075.jpg", "report": "Patient suspected of glaucoma due to cupping, has myopic astigmatism, Type 1 diabetes without retinopathy, and scheduled for silent sinus syndrome surgery."}
{"question_id": 142, "question": "Is the patient suspected to have open angle glaucoma in both eyes?\n", "answer": "Yes.", "image": "slo_fundus_08077.jpg", "report": "Patient referred for suspected open angle glaucoma with low risk in both eyes. Risk factors include family history of glaucoma (mother) and long-term steroid use. No history of eye trauma or other eye procedures. Undergone IOP tonometry with pressure 23 both eyes. No glaucoma medication issues or allergies. Advised follow up."}
{"question_id": 143, "question": "Is the patient considered to have a low risk for developing glaucoma?\n", "answer": "Yes.", "image": "slo_fundus_08077.jpg", "report": "Patient referred for suspected open angle glaucoma with low risk in both eyes. Risk factors include family history of glaucoma (mother) and long-term steroid use. No history of eye trauma or other eye procedures. Undergone IOP tonometry with pressure 23 both eyes. No glaucoma medication issues or allergies. Advised follow up."}
{"question_id": 144, "question": "Does the patient have a family history of glaucoma?\n", "answer": "Yes.", "image": "slo_fundus_08077.jpg", "report": "Patient referred for suspected open angle glaucoma with low risk in both eyes. Risk factors include family history of glaucoma (mother) and long-term steroid use. No history of eye trauma or other eye procedures. Undergone IOP tonometry with pressure 23 both eyes. No glaucoma medication issues or allergies. Advised follow up."}
{"question_id": 145, "question": "Has the patient been using steroids for a long term?\n", "answer": "Yes.", "image": "slo_fundus_08077.jpg", "report": "Patient referred for suspected open angle glaucoma with low risk in both eyes. Risk factors include family history of glaucoma (mother) and long-term steroid use. No history of eye trauma or other eye procedures. Undergone IOP tonometry with pressure 23 both eyes. No glaucoma medication issues or allergies. Advised follow up."}
{"question_id": 146, "question": "Does the patient have any history of eye trauma?\n", "answer": "No.", "image": "slo_fundus_08077.jpg", "report": "Patient referred for suspected open angle glaucoma with low risk in both eyes. Risk factors include family history of glaucoma (mother) and long-term steroid use. No history of eye trauma or other eye procedures. Undergone IOP tonometry with pressure 23 both eyes. No glaucoma medication issues or allergies. Advised follow up."}
{"question_id": 147, "question": "Has the patient undergone any eye procedures?\n", "answer": "No.", "image": "slo_fundus_08077.jpg", "report": "Patient referred for suspected open angle glaucoma with low risk in both eyes. Risk factors include family history of glaucoma (mother) and long-term steroid use. No history of eye trauma or other eye procedures. Undergone IOP tonometry with pressure 23 both eyes. No glaucoma medication issues or allergies. Advised follow up."}
{"question_id": 148, "question": "Was the intraocular pressure (IOP) measured at 23 in both eyes?\n", "answer": "Yes.", "image": "slo_fundus_08077.jpg", "report": "Patient referred for suspected open angle glaucoma with low risk in both eyes. Risk factors include family history of glaucoma (mother) and long-term steroid use. No history of eye trauma or other eye procedures. Undergone IOP tonometry with pressure 23 both eyes. No glaucoma medication issues or allergies. Advised follow up."}
{"question_id": 149, "question": "Has the patient reported any issues or allergies with glaucoma medications?\n", "answer": "No.", "image": "slo_fundus_08077.jpg", "report": "Patient referred for suspected open angle glaucoma with low risk in both eyes. Risk factors include family history of glaucoma (mother) and long-term steroid use. No history of eye trauma or other eye procedures. Undergone IOP tonometry with pressure 23 both eyes. No glaucoma medication issues or allergies. Advised follow up."}
{"question_id": 150, "question": "Has the patient been advised to follow up for the suspected condition?\n", "answer": "Yes.", "image": "slo_fundus_08077.jpg", "report": "Patient referred for suspected open angle glaucoma with low risk in both eyes. Risk factors include family history of glaucoma (mother) and long-term steroid use. No history of eye trauma or other eye procedures. Undergone IOP tonometry with pressure 23 both eyes. No glaucoma medication issues or allergies. Advised follow up."}
{"question_id": 151, "question": "Does the patient have a posterior vitreous detachment (PVD) in the right eye?\n", "answer": "Yes.", "image": "slo_fundus_08078.jpg", "report": "Patient has PVD in right eye, mild cataract in both eyes, and normal, non-glaucomatous cupping in both eyes. Yearly follow-up planned."}
{"question_id": 152, "question": "Is there a mild cataract present in both eyes?\n", "answer": "Yes.", "image": "slo_fundus_08078.jpg", "report": "Patient has PVD in right eye, mild cataract in both eyes, and normal, non-glaucomatous cupping in both eyes. Yearly follow-up planned."}
{"question_id": 153, "question": "Is the cupping observed in both eyes non-glaucomatous?\n", "answer": "Yes.", "image": "slo_fundus_08078.jpg", "report": "Patient has PVD in right eye, mild cataract in both eyes, and normal, non-glaucomatous cupping in both eyes. Yearly follow-up planned."}
{"question_id": 154, "question": "Is the patient scheduled for a yearly follow-up?\n", "answer": "Yes.", "image": "slo_fundus_08078.jpg", "report": "Patient has PVD in right eye, mild cataract in both eyes, and normal, non-glaucomatous cupping in both eyes. Yearly follow-up planned."}
{"question_id": 155, "question": "Has Madeline undergone glaucoma surgery in her left eye?\n", "answer": "Yes.", "image": "slo_fundus_08083.jpg", "report": "Madeline recently underwent glaucoma surgery in left eye. Her conditions include open angle glaucoma in both eyes, pseudophakia, astigmatism, myopia, presbyopia, and asthma. Showing improvement, but further treatment may be considered."}
{"question_id": 156, "question": "Does Madeline have open angle glaucoma in both eyes?\n", "answer": "Yes.", "image": "slo_fundus_08083.jpg", "report": "Madeline recently underwent glaucoma surgery in left eye. Her conditions include open angle glaucoma in both eyes, pseudophakia, astigmatism, myopia, presbyopia, and asthma. Showing improvement, but further treatment may be considered."}
{"question_id": 157, "question": "Is Madeline diagnosed with pseudophakia?\n", "answer": "Yes.", "image": "slo_fundus_08083.jpg", "report": "Madeline recently underwent glaucoma surgery in left eye. Her conditions include open angle glaucoma in both eyes, pseudophakia, astigmatism, myopia, presbyopia, and asthma. Showing improvement, but further treatment may be considered."}
{"question_id": 158, "question": "Does Madeline have astigmatism?\n", "answer": "Yes.", "image": "slo_fundus_08083.jpg", "report": "Madeline recently underwent glaucoma surgery in left eye. Her conditions include open angle glaucoma in both eyes, pseudophakia, astigmatism, myopia, presbyopia, and asthma. Showing improvement, but further treatment may be considered."}
{"question_id": 159, "question": "Is Madeline myopic?\n", "answer": "Yes.", "image": "slo_fundus_08083.jpg", "report": "Madeline recently underwent glaucoma surgery in left eye. Her conditions include open angle glaucoma in both eyes, pseudophakia, astigmatism, myopia, presbyopia, and asthma. Showing improvement, but further treatment may be considered."}
{"question_id": 160, "question": "Does Madeline suffer from presbyopia?\n", "answer": "Yes.", "image": "slo_fundus_08083.jpg", "report": "Madeline recently underwent glaucoma surgery in left eye. Her conditions include open angle glaucoma in both eyes, pseudophakia, astigmatism, myopia, presbyopia, and asthma. Showing improvement, but further treatment may be considered."}
{"question_id": 161, "question": "Does Madeline have asthma?\n", "answer": "Yes.", "image": "slo_fundus_08083.jpg", "report": "Madeline recently underwent glaucoma surgery in left eye. Her conditions include open angle glaucoma in both eyes, pseudophakia, astigmatism, myopia, presbyopia, and asthma. Showing improvement, but further treatment may be considered."}
{"question_id": 162, "question": "Is Madeline showing improvement after the recent glaucoma surgery?\n", "answer": "Yes.", "image": "slo_fundus_08083.jpg", "report": "Madeline recently underwent glaucoma surgery in left eye. Her conditions include open angle glaucoma in both eyes, pseudophakia, astigmatism, myopia, presbyopia, and asthma. Showing improvement, but further treatment may be considered."}
{"question_id": 163, "question": "Might further treatment be considered for Madeline?\n", "answer": "Yes.", "image": "slo_fundus_08083.jpg", "report": "Madeline recently underwent glaucoma surgery in left eye. Her conditions include open angle glaucoma in both eyes, pseudophakia, astigmatism, myopia, presbyopia, and asthma. Showing improvement, but further treatment may be considered."}
{"question_id": 164, "question": "Is the patient currently on medication for various conditions?\n", "answer": "Yes.", "image": "slo_fundus_08096.jpg", "report": "The patient is currently taking econazole, sulfacetamide sodium-sulfur, valacyclovir, and acetaminophen-codeine for various conditions. They underwent Humphrey Visual Field and OCT optic nerve tests. Conditions include varicose veins and hypertension. No mention of glaucoma."}
{"question_id": 165, "question": "Has the patient undergone Humphrey Visual Field testing?\n", "answer": "Yes.", "image": "slo_fundus_08096.jpg", "report": "The patient is currently taking econazole, sulfacetamide sodium-sulfur, valacyclovir, and acetaminophen-codeine for various conditions. They underwent Humphrey Visual Field and OCT optic nerve tests. Conditions include varicose veins and hypertension. No mention of glaucoma."}
{"question_id": 166, "question": "Has the patient undergone OCT optic nerve testing?\n", "answer": "Yes.", "image": "slo_fundus_08096.jpg", "report": "The patient is currently taking econazole, sulfacetamide sodium-sulfur, valacyclovir, and acetaminophen-codeine for various conditions. They underwent Humphrey Visual Field and OCT optic nerve tests. Conditions include varicose veins and hypertension. No mention of glaucoma."}
{"question_id": 167, "question": "Does the patient have a condition involving varicose veins?\n", "answer": "Yes.", "image": "slo_fundus_08096.jpg", "report": "The patient is currently taking econazole, sulfacetamide sodium-sulfur, valacyclovir, and acetaminophen-codeine for various conditions. They underwent Humphrey Visual Field and OCT optic nerve tests. Conditions include varicose veins and hypertension. No mention of glaucoma."}
{"question_id": 168, "question": "Is hypertension one of the patient's conditions?\n", "answer": "Yes.", "image": "slo_fundus_08096.jpg", "report": "The patient is currently taking econazole, sulfacetamide sodium-sulfur, valacyclovir, and acetaminophen-codeine for various conditions. They underwent Humphrey Visual Field and OCT optic nerve tests. Conditions include varicose veins and hypertension. No mention of glaucoma."}
{"question_id": 169, "question": "Is there any mention of glaucoma in the patient's summary?\n", "answer": "No.", "image": "slo_fundus_08096.jpg", "report": "The patient is currently taking econazole, sulfacetamide sodium-sulfur, valacyclovir, and acetaminophen-codeine for various conditions. They underwent Humphrey Visual Field and OCT optic nerve tests. Conditions include varicose veins and hypertension. No mention of glaucoma."}
{"question_id": 170, "question": "Does the patient have a history of hypertension?\n", "answer": "Yes.", "image": "slo_fundus_08097.jpg", "report": "63-year-old patient with history of hypertension, hyperlipidemia, diabetes, GERD, back pain, and thyroidectomy for Graves' disease. No glaucoma mentioned but patient has controlled hyperglycemia, mild cataracts, occasional floaters, and dry eyes.\n"}
{"question_id": 171, "question": "Is there a mention of glaucoma in the patient's history?\n", "answer": "No.", "image": "slo_fundus_08097.jpg", "report": "63-year-old patient with history of hypertension, hyperlipidemia, diabetes, GERD, back pain, and thyroidectomy for Graves' disease. No glaucoma mentioned but patient has controlled hyperglycemia, mild cataracts, occasional floaters, and dry eyes.\n"}
{"question_id": 172, "question": "Has the patient undergone thyroidectomy for Graves' disease?\n", "answer": "Yes.", "image": "slo_fundus_08097.jpg", "report": "63-year-old patient with history of hypertension, hyperlipidemia, diabetes, GERD, back pain, and thyroidectomy for Graves' disease. No glaucoma mentioned but patient has controlled hyperglycemia, mild cataracts, occasional floaters, and dry eyes.\n"}
{"question_id": 173, "question": "Does the patient suffer from controlled hyperglycemia?\n", "answer": "Yes.", "image": "slo_fundus_08097.jpg", "report": "63-year-old patient with history of hypertension, hyperlipidemia, diabetes, GERD, back pain, and thyroidectomy for Graves' disease. No glaucoma mentioned but patient has controlled hyperglycemia, mild cataracts, occasional floaters, and dry eyes.\n"}
{"question_id": 174, "question": "Are mild cataracts present in the patient's eyes?\n", "answer": "Yes.", "image": "slo_fundus_08097.jpg", "report": "63-year-old patient with history of hypertension, hyperlipidemia, diabetes, GERD, back pain, and thyroidectomy for Graves' disease. No glaucoma mentioned but patient has controlled hyperglycemia, mild cataracts, occasional floaters, and dry eyes.\n"}
{"question_id": 175, "question": "Does the patient experience occasional floaters?\n", "answer": "Yes.", "image": "slo_fundus_08097.jpg", "report": "63-year-old patient with history of hypertension, hyperlipidemia, diabetes, GERD, back pain, and thyroidectomy for Graves' disease. No glaucoma mentioned but patient has controlled hyperglycemia, mild cataracts, occasional floaters, and dry eyes.\n"}
{"question_id": 176, "question": "Does the patient have dry eyes?\n", "answer": "Yes.", "image": "slo_fundus_08097.jpg", "report": "63-year-old patient with history of hypertension, hyperlipidemia, diabetes, GERD, back pain, and thyroidectomy for Graves' disease. No glaucoma mentioned but patient has controlled hyperglycemia, mild cataracts, occasional floaters, and dry eyes.\n"}
{"question_id": 177, "question": "Does the patient have a history of poor compliance with glaucoma treatments?\n", "answer": "Yes.", "image": "slo_fundus_08101.jpg", "report": "Patient has history of poor compliance with glaucoma treatments. Diagnosis: mild glaucoma. Medications: latanoprost, timolol. Glaucoma procedures performed on both eyes. Assessment: thin cornea, progression of vision field loss, irreversible nature of glaucoma discussed. Plan: restart latanoprost and timolol."}
{"question_id": 178, "question": "Is the diagnosis for the patient mild glaucoma?\n", "answer": "Yes.", "image": "slo_fundus_08101.jpg", "report": "Patient has history of poor compliance with glaucoma treatments. Diagnosis: mild glaucoma. Medications: latanoprost, timolol. Glaucoma procedures performed on both eyes. Assessment: thin cornea, progression of vision field loss, irreversible nature of glaucoma discussed. Plan: restart latanoprost and timolol."}
{"question_id": 179, "question": "Are latanoprost and timolol the medications prescribed for the patient's glaucoma?\n", "answer": "Yes.", "image": "slo_fundus_08101.jpg", "report": "Patient has history of poor compliance with glaucoma treatments. Diagnosis: mild glaucoma. Medications: latanoprost, timolol. Glaucoma procedures performed on both eyes. Assessment: thin cornea, progression of vision field loss, irreversible nature of glaucoma discussed. Plan: restart latanoprost and timolol."}
{"question_id": 180, "question": "Has the patient undergone glaucoma procedures on both eyes?\n", "answer": "Yes.", "image": "slo_fundus_08101.jpg", "report": "Patient has history of poor compliance with glaucoma treatments. Diagnosis: mild glaucoma. Medications: latanoprost, timolol. Glaucoma procedures performed on both eyes. Assessment: thin cornea, progression of vision field loss, irreversible nature of glaucoma discussed. Plan: restart latanoprost and timolol."}
{"question_id": 181, "question": "Does the assessment indicate that the patient has a thin cornea?\n", "answer": "Yes.", "image": "slo_fundus_08101.jpg", "report": "Patient has history of poor compliance with glaucoma treatments. Diagnosis: mild glaucoma. Medications: latanoprost, timolol. Glaucoma procedures performed on both eyes. Assessment: thin cornea, progression of vision field loss, irreversible nature of glaucoma discussed. Plan: restart latanoprost and timolol."}
{"question_id": 182, "question": "Is there progression of vision field loss noted in the patient's condition?\n", "answer": "Yes.", "image": "slo_fundus_08101.jpg", "report": "Patient has history of poor compliance with glaucoma treatments. Diagnosis: mild glaucoma. Medications: latanoprost, timolol. Glaucoma procedures performed on both eyes. Assessment: thin cornea, progression of vision field loss, irreversible nature of glaucoma discussed. Plan: restart latanoprost and timolol."}
{"question_id": 183, "question": "Was the irreversible nature of glaucoma discussed with the patient?\n", "answer": "Yes.", "image": "slo_fundus_08101.jpg", "report": "Patient has history of poor compliance with glaucoma treatments. Diagnosis: mild glaucoma. Medications: latanoprost, timolol. Glaucoma procedures performed on both eyes. Assessment: thin cornea, progression of vision field loss, irreversible nature of glaucoma discussed. Plan: restart latanoprost and timolol."}
{"question_id": 184, "question": "Is the plan to restart the patient on latanoprost and timolol for treatment?\n", "answer": "Yes.", "image": "slo_fundus_08101.jpg", "report": "Patient has history of poor compliance with glaucoma treatments. Diagnosis: mild glaucoma. Medications: latanoprost, timolol. Glaucoma procedures performed on both eyes. Assessment: thin cornea, progression of vision field loss, irreversible nature of glaucoma discussed. Plan: restart latanoprost and timolol."}
{"question_id": 185, "question": "Does the patient have a history of breast cancer?\n", "answer": "Yes.", "image": "slo_fundus_08106.jpg", "report": "Patient with breast cancer history follows up for idiopathic intracranial hypertension (iih). Despite weight gain, visual status remains stable. Concerns over increased intracranial pressure discussed. No glaucoma mentioned."}
{"question_id": 186, "question": "Is the patient being followed up for idiopathic intracranial hypertension?\n", "answer": "Yes.", "image": "slo_fundus_08106.jpg", "report": "Patient with breast cancer history follows up for idiopathic intracranial hypertension (iih). Despite weight gain, visual status remains stable. Concerns over increased intracranial pressure discussed. No glaucoma mentioned."}
{"question_id": 187, "question": "Has the patient experienced weight gain recently?\n", "answer": "Yes.", "image": "slo_fundus_08106.jpg", "report": "Patient with breast cancer history follows up for idiopathic intracranial hypertension (iih). Despite weight gain, visual status remains stable. Concerns over increased intracranial pressure discussed. No glaucoma mentioned."}
{"question_id": 188, "question": "Has the patient's visual status remained stable despite the weight gain?\n", "answer": "Yes.", "image": "slo_fundus_08106.jpg", "report": "Patient with breast cancer history follows up for idiopathic intracranial hypertension (iih). Despite weight gain, visual status remains stable. Concerns over increased intracranial pressure discussed. No glaucoma mentioned."}
{"question_id": 189, "question": "Were concerns over increased intracranial pressure discussed with the patient?\n", "answer": "Yes.", "image": "slo_fundus_08106.jpg", "report": "Patient with breast cancer history follows up for idiopathic intracranial hypertension (iih). Despite weight gain, visual status remains stable. Concerns over increased intracranial pressure discussed. No glaucoma mentioned."}
{"question_id": 190, "question": "Is there any mention of glaucoma in the patient's history?\n", "answer": "No.", "image": "slo_fundus_08106.jpg", "report": "Patient with breast cancer history follows up for idiopathic intracranial hypertension (iih). Despite weight gain, visual status remains stable. Concerns over increased intracranial pressure discussed. No glaucoma mentioned."}
{"question_id": 191, "question": "Does the patient have type 2 diabetes?\n", "answer": "Yes.", "image": "slo_fundus_08107.jpg", "report": "Patient has diabetes type 2, history of stroke with left homonymous hemianopsia. RNFL showing superior thinning indicators of glaucoma. Cataracts present but not visually significant. Glaucoma consultation advised."}
{"question_id": 192, "question": "Has the patient had a history of stroke?\n", "answer": "Yes.", "image": "slo_fundus_08107.jpg", "report": "Patient has diabetes type 2, history of stroke with left homonymous hemianopsia. RNFL showing superior thinning indicators of glaucoma. Cataracts present but not visually significant. Glaucoma consultation advised."}
{"question_id": 193, "question": "Does the patient suffer from left homonymous hemianopsia?\n", "answer": "Yes.", "image": "slo_fundus_08107.jpg", "report": "Patient has diabetes type 2, history of stroke with left homonymous hemianopsia. RNFL showing superior thinning indicators of glaucoma. Cataracts present but not visually significant. Glaucoma consultation advised."}
{"question_id": 194, "question": "Is there evidence of superior thinning in the RNFL indicative of glaucoma?\n", "answer": "Yes.", "image": "slo_fundus_08107.jpg", "report": "Patient has diabetes type 2, history of stroke with left homonymous hemianopsia. RNFL showing superior thinning indicators of glaucoma. Cataracts present but not visually significant. Glaucoma consultation advised."}
{"question_id": 195, "question": "Are cataracts present in the patient's eyes?\n", "answer": "Yes.", "image": "slo_fundus_08107.jpg", "report": "Patient has diabetes type 2, history of stroke with left homonymous hemianopsia. RNFL showing superior thinning indicators of glaucoma. Cataracts present but not visually significant. Glaucoma consultation advised."}
{"question_id": 196, "question": "Are the present cataracts considered visually significant?\n", "answer": "No.", "image": "slo_fundus_08107.jpg", "report": "Patient has diabetes type 2, history of stroke with left homonymous hemianopsia. RNFL showing superior thinning indicators of glaucoma. Cataracts present but not visually significant. Glaucoma consultation advised."}
{"question_id": 197, "question": "Has a glaucoma consultation been advised for the patient?\n", "answer": "Yes.", "image": "slo_fundus_08107.jpg", "report": "Patient has diabetes type 2, history of stroke with left homonymous hemianopsia. RNFL showing superior thinning indicators of glaucoma. Cataracts present but not visually significant. Glaucoma consultation advised."}
{"question_id": 198, "question": "Does the patient have cataracts?\n", "answer": "Yes.", "image": "slo_fundus_08109.jpg", "report": "80 y.o. patient with cataracts and a history of glaucoma. Cataract surgery was delayed due to COVID-19. The patient hasn't been using prescribed medication, resulting in high intraocular pressure (IOP)."}
{"question_id": 199, "question": "Does the patient have a history of glaucoma?\n", "answer": "Yes.", "image": "slo_fundus_08109.jpg", "report": "80 y.o. patient with cataracts and a history of glaucoma. Cataract surgery was delayed due to COVID-19. The patient hasn't been using prescribed medication, resulting in high intraocular pressure (IOP)."}
{"question_id": 200, "question": "Was the cataract surgery delayed due to COVID-19?\n", "answer": "Yes.", "image": "slo_fundus_08109.jpg", "report": "80 y.o. patient with cataracts and a history of glaucoma. Cataract surgery was delayed due to COVID-19. The patient hasn't been using prescribed medication, resulting in high intraocular pressure (IOP)."}
{"question_id": 201, "question": "Has the patient not been using the prescribed glaucoma medication?\n", "answer": "Yes.", "image": "slo_fundus_08109.jpg", "report": "80 y.o. patient with cataracts and a history of glaucoma. Cataract surgery was delayed due to COVID-19. The patient hasn't been using prescribed medication, resulting in high intraocular pressure (IOP)."}
{"question_id": 202, "question": "Is the patient's intraocular pressure (IOP) high?\n", "answer": "Yes.", "image": "slo_fundus_08109.jpg", "report": "80 y.o. patient with cataracts and a history of glaucoma. Cataract surgery was delayed due to COVID-19. The patient hasn't been using prescribed medication, resulting in high intraocular pressure (IOP)."}
{"question_id": 203, "question": "Is the patient suspected of having glaucoma because of an increased cup-to-disc ratio (cdr)?\n", "answer": "Yes.", "image": "slo_fundus_08112.jpg", "report": "51 y.o. female, suspected glaucoma due to increased cdr. Negative family history, normal OCT, mild nonspecific changes OD in HVF. Monitoring refractive error."}
{"question_id": 204, "question": "Does the patient have a negative family history for glaucoma?\n", "answer": "Yes.", "image": "slo_fundus_08112.jpg", "report": "51 y.o. female, suspected glaucoma due to increased cdr. Negative family history, normal OCT, mild nonspecific changes OD in HVF. Monitoring refractive error."}
{"question_id": 205, "question": "Are the OCT (Optical Coherence Tomography) findings normal for this patient?\n", "answer": "Yes.", "image": "slo_fundus_08112.jpg", "report": "51 y.o. female, suspected glaucoma due to increased cdr. Negative family history, normal OCT, mild nonspecific changes OD in HVF. Monitoring refractive error."}
{"question_id": 206, "question": "Are there mild nonspecific changes in the visual field (HVF) of the right eye (OD)?\n", "answer": "Yes.", "image": "slo_fundus_08112.jpg", "report": "51 y.o. female, suspected glaucoma due to increased cdr. Negative family history, normal OCT, mild nonspecific changes OD in HVF. Monitoring refractive error."}
{"question_id": 207, "question": "Is the patient currently being monitored for refractive error?\n", "answer": "Yes.", "image": "slo_fundus_08112.jpg", "report": "51 y.o. female, suspected glaucoma due to increased cdr. Negative family history, normal OCT, mild nonspecific changes OD in HVF. Monitoring refractive error."}
{"question_id": 208, "question": "Is the patient considered a glaucoma suspect?\n", "answer": "Yes.", "image": "slo_fundus_08119.jpg", "report": "Patient is a glaucoma suspect but has normal visual fields in both eyes. Intraocular pressure and testing show stable results. No treatment initiated, planned for monitoring."}
{"question_id": 209, "question": "Does the patient have normal visual fields in both eyes?\n", "answer": "Yes.", "image": "slo_fundus_08119.jpg", "report": "Patient is a glaucoma suspect but has normal visual fields in both eyes. Intraocular pressure and testing show stable results. No treatment initiated, planned for monitoring."}
{"question_id": 210, "question": "Are the intraocular pressure and testing results stable for this patient?\n", "answer": "Yes.", "image": "slo_fundus_08119.jpg", "report": "Patient is a glaucoma suspect but has normal visual fields in both eyes. Intraocular pressure and testing show stable results. No treatment initiated, planned for monitoring."}
{"question_id": 211, "question": "Has any treatment been initiated for the patient's condition?\n", "answer": "No.", "image": "slo_fundus_08119.jpg", "report": "Patient is a glaucoma suspect but has normal visual fields in both eyes. Intraocular pressure and testing show stable results. No treatment initiated, planned for monitoring."}
{"question_id": 212, "question": "Is the patient's condition planned to be managed through monitoring?\n", "answer": "Yes.", "image": "slo_fundus_08119.jpg", "report": "Patient is a glaucoma suspect but has normal visual fields in both eyes. Intraocular pressure and testing show stable results. No treatment initiated, planned for monitoring."}
{"question_id": 213, "question": "Does the patient have a history of primary open-angle glaucoma (POAG)?\n", "answer": "Yes.", "image": "slo_fundus_08120.jpg", "report": "The 67 y.o. male patient has a history of glaucoma (POAG), with an increased c:d ratio and controlled IOP. He also shows ocular scars and has a history of ocular migraines and scleral lens wear."}
{"question_id": 214, "question": "Is there an increased cup-to-disc (c:d) ratio evident in the patient's fundus image?\n", "answer": "Yes.", "image": "slo_fundus_08120.jpg", "report": "The 67 y.o. male patient has a history of glaucoma (POAG), with an increased c:d ratio and controlled IOP. He also shows ocular scars and has a history of ocular migraines and scleral lens wear."}
{"question_id": 215, "question": "Is the intraocular pressure (IOP) currently controlled for this patient?\n", "answer": "Yes.", "image": "slo_fundus_08120.jpg", "report": "The 67 y.o. male patient has a history of glaucoma (POAG), with an increased c:d ratio and controlled IOP. He also shows ocular scars and has a history of ocular migraines and scleral lens wear."}
{"question_id": 216, "question": "Are there ocular scars present in the patient's eye?\n", "answer": "Yes.", "image": "slo_fundus_08120.jpg", "report": "The 67 y.o. male patient has a history of glaucoma (POAG), with an increased c:d ratio and controlled IOP. He also shows ocular scars and has a history of ocular migraines and scleral lens wear."}
{"question_id": 217, "question": "Does the patient have a history of ocular migraines?\n", "answer": "Yes.", "image": "slo_fundus_08120.jpg", "report": "The 67 y.o. male patient has a history of glaucoma (POAG), with an increased c:d ratio and controlled IOP. He also shows ocular scars and has a history of ocular migraines and scleral lens wear."}
{"question_id": 218, "question": "Is the patient currently wearing scleral lenses or has a history of wearing them?\n", "answer": "Yes.", "image": "slo_fundus_08120.jpg", "report": "The 67 y.o. male patient has a history of glaucoma (POAG), with an increased c:d ratio and controlled IOP. He also shows ocular scars and has a history of ocular migraines and scleral lens wear."}
{"question_id": 219, "question": "Does the patient have a diagnosis of glaucoma?\n", "answer": "No.", "image": "slo_fundus_08127.jpg", "report": "27 y.o. white, non-hispanic female. No diagnosis of glaucoma. Exam as needed. Assisted by Huy Nguyen, PGY3."}
{"question_id": 220, "question": "Is the patient required to have eye exams as needed?\n", "answer": "Yes.", "image": "slo_fundus_08127.jpg", "report": "27 y.o. white, non-hispanic female. No diagnosis of glaucoma. Exam as needed. Assisted by Huy Nguyen, PGY3."}
{"question_id": 221, "question": "Was the examination assisted by Huy Nguyen, PGY3?\n", "answer": "Yes.", "image": "slo_fundus_08127.jpg", "report": "27 y.o. white, non-hispanic female. No diagnosis of glaucoma. Exam as needed. Assisted by Huy Nguyen, PGY3."}
{"question_id": 222, "question": "Is the patient currently using timolol 0.5% ophthalmic gel for both eyes?\n", "answer": "Yes.", "image": "slo_fundus_08132.jpg", "report": "The patient is taking timolol 0.5% ophthalmic gel, dropped in each eye daily. They are also taking trazodone orally. The patient has been referred for visual field and optic nerve examinations. No mention of glaucoma. Other health conditions include chronic renal impairment, hyperkalemia, hyperlipidemia, gout, hypothyroidism, GERD, and hypertension.\n"}
{"question_id": 223, "question": "Is trazodone being taken by the patient orally?\n", "answer": "Yes.", "image": "slo_fundus_08132.jpg", "report": "The patient is taking timolol 0.5% ophthalmic gel, dropped in each eye daily. They are also taking trazodone orally. The patient has been referred for visual field and optic nerve examinations. No mention of glaucoma. Other health conditions include chronic renal impairment, hyperkalemia, hyperlipidemia, gout, hypothyroidism, GERD, and hypertension.\n"}
{"question_id": 224, "question": "Has the patient been referred for visual field testing?\n", "answer": "Yes.", "image": "slo_fundus_08132.jpg", "report": "The patient is taking timolol 0.5% ophthalmic gel, dropped in each eye daily. They are also taking trazodone orally. The patient has been referred for visual field and optic nerve examinations. No mention of glaucoma. Other health conditions include chronic renal impairment, hyperkalemia, hyperlipidemia, gout, hypothyroidism, GERD, and hypertension.\n"}
{"question_id": 225, "question": "Has the patient been referred for optic nerve examinations?\n", "answer": "Yes.", "image": "slo_fundus_08132.jpg", "report": "The patient is taking timolol 0.5% ophthalmic gel, dropped in each eye daily. They are also taking trazodone orally. The patient has been referred for visual field and optic nerve examinations. No mention of glaucoma. Other health conditions include chronic renal impairment, hyperkalemia, hyperlipidemia, gout, hypothyroidism, GERD, and hypertension.\n"}
{"question_id": 226, "question": "Is there any mention of the patient having glaucoma?\n", "answer": "No.", "image": "slo_fundus_08132.jpg", "report": "The patient is taking timolol 0.5% ophthalmic gel, dropped in each eye daily. They are also taking trazodone orally. The patient has been referred for visual field and optic nerve examinations. No mention of glaucoma. Other health conditions include chronic renal impairment, hyperkalemia, hyperlipidemia, gout, hypothyroidism, GERD, and hypertension.\n"}
{"question_id": 227, "question": "Does the patient have chronic renal impairment?\n", "answer": "Yes.", "image": "slo_fundus_08132.jpg", "report": "The patient is taking timolol 0.5% ophthalmic gel, dropped in each eye daily. They are also taking trazodone orally. The patient has been referred for visual field and optic nerve examinations. No mention of glaucoma. Other health conditions include chronic renal impairment, hyperkalemia, hyperlipidemia, gout, hypothyroidism, GERD, and hypertension.\n"}
{"question_id": 228, "question": "Does the patient suffer from hyperkalemia?\n", "answer": "Yes.", "image": "slo_fundus_08132.jpg", "report": "The patient is taking timolol 0.5% ophthalmic gel, dropped in each eye daily. They are also taking trazodone orally. The patient has been referred for visual field and optic nerve examinations. No mention of glaucoma. Other health conditions include chronic renal impairment, hyperkalemia, hyperlipidemia, gout, hypothyroidism, GERD, and hypertension.\n"}
{"question_id": 229, "question": "Is hyperlipidemia one of the patient's health conditions?\n", "answer": "Yes.", "image": "slo_fundus_08132.jpg", "report": "The patient is taking timolol 0.5% ophthalmic gel, dropped in each eye daily. They are also taking trazodone orally. The patient has been referred for visual field and optic nerve examinations. No mention of glaucoma. Other health conditions include chronic renal impairment, hyperkalemia, hyperlipidemia, gout, hypothyroidism, GERD, and hypertension.\n"}
{"question_id": 230, "question": "Does the patient have a history of gout?\n", "answer": "Yes.", "image": "slo_fundus_08132.jpg", "report": "The patient is taking timolol 0.5% ophthalmic gel, dropped in each eye daily. They are also taking trazodone orally. The patient has been referred for visual field and optic nerve examinations. No mention of glaucoma. Other health conditions include chronic renal impairment, hyperkalemia, hyperlipidemia, gout, hypothyroidism, GERD, and hypertension.\n"}
{"question_id": 231, "question": "Is hypothyroidism a condition that the patient is dealing with?\n", "answer": "Yes.", "image": "slo_fundus_08132.jpg", "report": "The patient is taking timolol 0.5% ophthalmic gel, dropped in each eye daily. They are also taking trazodone orally. The patient has been referred for visual field and optic nerve examinations. No mention of glaucoma. Other health conditions include chronic renal impairment, hyperkalemia, hyperlipidemia, gout, hypothyroidism, GERD, and hypertension.\n"}
{"question_id": 232, "question": "Does the patient suffer from gastroesophageal reflux disease (GERD)?\n", "answer": "Yes.", "image": "slo_fundus_08132.jpg", "report": "The patient is taking timolol 0.5% ophthalmic gel, dropped in each eye daily. They are also taking trazodone orally. The patient has been referred for visual field and optic nerve examinations. No mention of glaucoma. Other health conditions include chronic renal impairment, hyperkalemia, hyperlipidemia, gout, hypothyroidism, GERD, and hypertension.\n"}
{"question_id": 233, "question": "Is the patient hypertensive?\n", "answer": "Yes.", "image": "slo_fundus_08132.jpg", "report": "The patient is taking timolol 0.5% ophthalmic gel, dropped in each eye daily. They are also taking trazodone orally. The patient has been referred for visual field and optic nerve examinations. No mention of glaucoma. Other health conditions include chronic renal impairment, hyperkalemia, hyperlipidemia, gout, hypothyroidism, GERD, and hypertension.\n"}
{"question_id": 234, "question": "Has the patient been advised to use warm compresses for their eye condition?\n", "answer": "Yes.", "image": "slo_fundus_08135.jpg", "report": "The patient has been advised to use warm compresses and stop eye rubbing. Potential referral for ABMD. Needs to return to the Glaucoma Clinic for further tests."}
{"question_id": 235, "question": "Has the patient been instructed to stop rubbing their eyes?\n", "answer": "Yes.", "image": "slo_fundus_08135.jpg", "report": "The patient has been advised to use warm compresses and stop eye rubbing. Potential referral for ABMD. Needs to return to the Glaucoma Clinic for further tests."}
{"question_id": 236, "question": "Is there a potential referral for the patient for Anterior Basement Membrane Dystrophy (ABMD)?\n", "answer": "Yes.", "image": "slo_fundus_08135.jpg", "report": "The patient has been advised to use warm compresses and stop eye rubbing. Potential referral for ABMD. Needs to return to the Glaucoma Clinic for further tests."}
{"question_id": 237, "question": "Does the patient need to return to the Glaucoma Clinic for further tests?\n", "answer": "Yes.", "image": "slo_fundus_08135.jpg", "report": "The patient has been advised to use warm compresses and stop eye rubbing. Potential referral for ABMD. Needs to return to the Glaucoma Clinic for further tests."}
{"question_id": 238, "question": "Is the patient a suspect for narrow angle glaucoma?\n", "answer": "Yes.", "image": "slo_fundus_08136.jpg", "report": "Patient is a suspect of narrow angle glaucoma due to hereditary reasons. She previously suffered sudden vision loss and had been diagnosed with Posner-Schlossman syndrome. She's also had episodes of bright light vision, diagnosed as ocular migraines. She had laser peripheral iridotomy (LPI), which reduced the symptoms. The patient's intraocular pressure is currently acceptable and her visual field is stable, but she has mild posterior capsular opacification in right eye. Follow-up planned in 6 months."}
{"question_id": 239, "question": "Has the patient been diagnosed with Posner-Schlossman syndrome?\n", "answer": "Yes.", "image": "slo_fundus_08136.jpg", "report": "Patient is a suspect of narrow angle glaucoma due to hereditary reasons. She previously suffered sudden vision loss and had been diagnosed with Posner-Schlossman syndrome. She's also had episodes of bright light vision, diagnosed as ocular migraines. She had laser peripheral iridotomy (LPI), which reduced the symptoms. The patient's intraocular pressure is currently acceptable and her visual field is stable, but she has mild posterior capsular opacification in right eye. Follow-up planned in 6 months."}
{"question_id": 240, "question": "Has the patient experienced episodes diagnosed as ocular migraines?\n", "answer": "Yes.", "image": "slo_fundus_08136.jpg", "report": "Patient is a suspect of narrow angle glaucoma due to hereditary reasons. She previously suffered sudden vision loss and had been diagnosed with Posner-Schlossman syndrome. She's also had episodes of bright light vision, diagnosed as ocular migraines. She had laser peripheral iridotomy (LPI), which reduced the symptoms. The patient's intraocular pressure is currently acceptable and her visual field is stable, but she has mild posterior capsular opacification in right eye. Follow-up planned in 6 months."}
{"question_id": 241, "question": "Did the patient undergo laser peripheral iridotomy (LPI)?\n", "answer": "Yes.", "image": "slo_fundus_08136.jpg", "report": "Patient is a suspect of narrow angle glaucoma due to hereditary reasons. She previously suffered sudden vision loss and had been diagnosed with Posner-Schlossman syndrome. She's also had episodes of bright light vision, diagnosed as ocular migraines. She had laser peripheral iridotomy (LPI), which reduced the symptoms. The patient's intraocular pressure is currently acceptable and her visual field is stable, but she has mild posterior capsular opacification in right eye. Follow-up planned in 6 months."}
{"question_id": 242, "question": "Has the laser peripheral iridotomy (LPI) helped reduce the patient\u2019s symptoms?\n", "answer": "Yes.", "image": "slo_fundus_08136.jpg", "report": "Patient is a suspect of narrow angle glaucoma due to hereditary reasons. She previously suffered sudden vision loss and had been diagnosed with Posner-Schlossman syndrome. She's also had episodes of bright light vision, diagnosed as ocular migraines. She had laser peripheral iridotomy (LPI), which reduced the symptoms. The patient's intraocular pressure is currently acceptable and her visual field is stable, but she has mild posterior capsular opacification in right eye. Follow-up planned in 6 months."}
{"question_id": 243, "question": "Is the patient\u2019s intraocular pressure currently at an acceptable level?\n", "answer": "Yes.", "image": "slo_fundus_08136.jpg", "report": "Patient is a suspect of narrow angle glaucoma due to hereditary reasons. She previously suffered sudden vision loss and had been diagnosed with Posner-Schlossman syndrome. She's also had episodes of bright light vision, diagnosed as ocular migraines. She had laser peripheral iridotomy (LPI), which reduced the symptoms. The patient's intraocular pressure is currently acceptable and her visual field is stable, but she has mild posterior capsular opacification in right eye. Follow-up planned in 6 months."}
{"question_id": 244, "question": "Is the patient\u2019s visual field currently stable?\n", "answer": "Yes.", "image": "slo_fundus_08136.jpg", "report": "Patient is a suspect of narrow angle glaucoma due to hereditary reasons. She previously suffered sudden vision loss and had been diagnosed with Posner-Schlossman syndrome. She's also had episodes of bright light vision, diagnosed as ocular migraines. She had laser peripheral iridotomy (LPI), which reduced the symptoms. The patient's intraocular pressure is currently acceptable and her visual field is stable, but she has mild posterior capsular opacification in right eye. Follow-up planned in 6 months."}
{"question_id": 245, "question": "Does the patient have mild posterior capsular opacification in the right eye?\n", "answer": "Yes.", "image": "slo_fundus_08136.jpg", "report": "Patient is a suspect of narrow angle glaucoma due to hereditary reasons. She previously suffered sudden vision loss and had been diagnosed with Posner-Schlossman syndrome. She's also had episodes of bright light vision, diagnosed as ocular migraines. She had laser peripheral iridotomy (LPI), which reduced the symptoms. The patient's intraocular pressure is currently acceptable and her visual field is stable, but she has mild posterior capsular opacification in right eye. Follow-up planned in 6 months."}
{"question_id": 246, "question": "Is a follow-up for the patient planned in 6 months?\n", "answer": "Yes.", "image": "slo_fundus_08136.jpg", "report": "Patient is a suspect of narrow angle glaucoma due to hereditary reasons. She previously suffered sudden vision loss and had been diagnosed with Posner-Schlossman syndrome. She's also had episodes of bright light vision, diagnosed as ocular migraines. She had laser peripheral iridotomy (LPI), which reduced the symptoms. The patient's intraocular pressure is currently acceptable and her visual field is stable, but she has mild posterior capsular opacification in right eye. Follow-up planned in 6 months."}
{"question_id": 247, "question": "Does the patient have glaucoma?\n", "answer": "Yes.", "image": "slo_fundus_08140.jpg", "report": "The patient has glaucoma. The intraocular pressure (IOP) is above target in both eyes, an additional medication (Rhopressa) was recommended due to new disc hemorrhage in right eye and increasing IOP, but the patient refused. Retinal detachment precautions reviewed."}
{"question_id": 248, "question": "Is the intraocular pressure above target in both eyes?\n", "answer": "Yes.", "image": "slo_fundus_08140.jpg", "report": "The patient has glaucoma. The intraocular pressure (IOP) is above target in both eyes, an additional medication (Rhopressa) was recommended due to new disc hemorrhage in right eye and increasing IOP, but the patient refused. Retinal detachment precautions reviewed."}
{"question_id": 249, "question": "Was Rhopressa recommended as an additional medication for this patient?\n