

| \n", " | 0: Pan_Interferon-response | \n", "1: Pan_Proliferation-S | \n", "2: Pan_Heat-stress | \n", "3: DC_pDC | \n", "4: B_Plasma | \n", "5: Pan_Proliferation-G2-M | \n", "6: DC_cDC2-MHCII | \n", "7: T_Treg-T-co-signaling | \n", "8: T_NK-cytotoxic | \n", "9: M_Monocyte-CD16 | \n", "... | \n", "77: B_Plasma-JCHAIN | \n", "78: T_CD4T-IL7R | \n", "MeC_79 | \n", "MeC_80 | \n", "81: Stroma_Fibroblast-VEGF | \n", "MeC_82 | \n", "83: Pan_Myeloid-fibroblast | \n", "MeC_84 | \n", "MeC_85 | \n", "overcluster | \n", "
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| bcc.su001.pre.tcell_AAACCTGCAGGGATTG | \n", "-0.819890 | \n", "-0.688164 | \n", "-1.293394 | \n", "-0.623175 | \n", "-0.619621 | \n", "-0.014213 | \n", "-0.421470 | \n", "-0.575049 | \n", "0.806688 | \n", "-0.228148 | \n", "... | \n", "-0.503919 | \n", "1.365941 | \n", "0.532829 | \n", "1.303657 | \n", "-0.015501 | \n", "-0.200811 | \n", "2.227211 | \n", "-2.101272 | \n", "0.964769 | \n", "103 | \n", "
| bcc.su001.pre.tcell_AAACGGGCATAGACTC | \n", "0.497730 | \n", "-0.781702 | \n", "-1.236870 | \n", "-0.225077 | \n", "-0.407063 | \n", "-0.196667 | \n", "-0.708806 | \n", "0.148677 | \n", "1.226127 | \n", "0.229111 | \n", "... | \n", "-0.964028 | \n", "-0.869057 | \n", "-0.948729 | \n", "0.932158 | \n", "-1.617307 | \n", "-0.813145 | \n", "-0.541694 | \n", "-1.985215 | \n", "0.821645 | \n", "71 | \n", "
| bcc.su001.pre.tcell_AAACGGGTCATACGGT | \n", "-0.853597 | \n", "0.389129 | \n", "2.834898 | \n", "-0.235956 | \n", "0.469343 | \n", "0.946867 | \n", "-0.673814 | \n", "0.078563 | \n", "1.469857 | \n", "0.388126 | \n", "... | \n", "-0.713808 | \n", "1.094122 | \n", "1.178537 | \n", "-2.930747 | \n", "-2.534621 | \n", "1.399297 | \n", "-0.640663 | \n", "2.175453 | \n", "-1.674753 | \n", "9 | \n", "
| bcc.su001.pre.tcell_AAAGATGAGACAGGCT | \n", "1.643644 | \n", "-0.217423 | \n", "-0.643116 | \n", "0.088754 | \n", "-0.523546 | \n", "-1.255705 | \n", "-0.849190 | \n", "0.658166 | \n", "-0.770305 | \n", "1.756781 | \n", "... | \n", "-1.132153 | \n", "1.547834 | \n", "-1.547482 | \n", "0.496351 | \n", "-1.177201 | \n", "-0.764956 | \n", "0.551764 | \n", "0.479404 | \n", "-0.165305 | \n", "8 | \n", "
| bcc.su001.pre.tcell_AAAGATGTCTGAGTGT | \n", "-0.904096 | \n", "-0.855004 | \n", "-1.025405 | \n", "-0.417323 | \n", "-0.265433 | \n", "-0.517993 | \n", "-0.371883 | \n", "-0.238967 | \n", "-1.225588 | \n", "0.211766 | \n", "... | \n", "0.743283 | \n", "2.142204 | \n", "0.523307 | \n", "0.401327 | \n", "-0.243886 | \n", "-0.139409 | \n", "1.541129 | \n", "-0.646087 | \n", "-0.965725 | \n", "40 | \n", "
| ... | \n", "... | \n", "... | \n", "... | \n", "... | \n", "... | \n", "... | \n", "... | \n", "... | \n", "... | \n", "... | \n", "... | \n", "... | \n", "... | \n", "... | \n", "... | \n", "... | \n", "... | \n", "... | \n", "... | \n", "... | \n", "... | \n", "
| bcc.su012.post.tcell_TTTGCGCGTCTTTCAT | \n", "-0.655006 | \n", "-0.323290 | \n", "1.357172 | \n", "-0.252120 | \n", "-0.477362 | \n", "-0.562883 | \n", "-0.469015 | \n", "-0.594926 | \n", "-0.978787 | \n", "0.131918 | \n", "... | \n", "0.224142 | \n", "1.476642 | \n", "1.258007 | \n", "-0.838055 | \n", "0.543334 | \n", "0.264970 | \n", "-0.528499 | \n", "1.782975 | \n", "-2.250962 | \n", "19 | \n", "
| bcc.su012.post.tcell_TTTGGTTCAGCCAGAA | \n", "-1.002944 | \n", "-0.177266 | \n", "1.441417 | \n", "-0.175024 | \n", "-0.643992 | \n", "-1.178595 | \n", "-1.009185 | \n", "0.391318 | \n", "0.190629 | \n", "1.112531 | \n", "... | \n", "0.111604 | \n", "0.727014 | \n", "0.063260 | \n", "0.221161 | \n", "1.290879 | \n", "0.011502 | \n", "-0.428551 | \n", "1.685099 | \n", "-0.775345 | \n", "15 | \n", "
| bcc.su012.post.tcell_TTTGTCAAGCACCGTC | \n", "-0.705487 | \n", "-0.384236 | \n", "1.495082 | \n", "-0.411420 | \n", "-0.401349 | \n", "-0.957136 | \n", "-1.487738 | \n", "0.004184 | \n", "-0.690182 | \n", "0.843381 | \n", "... | \n", "-0.196389 | \n", "-0.427286 | \n", "-0.727919 | \n", "-0.666853 | \n", "1.105166 | \n", "3.032268 | \n", "-0.136370 | \n", "1.011591 | \n", "-0.914623 | \n", "15 | \n", "
| bcc.su012.post.tcell_TTTGTCAAGTGAACGC | \n", "0.205688 | \n", "-0.372909 | \n", "1.382011 | \n", "0.256174 | \n", "-0.391342 | \n", "0.236742 | \n", "-1.236226 | \n", "1.282568 | \n", "0.039292 | \n", "0.352591 | \n", "... | \n", "-1.496709 | \n", "-0.348647 | \n", "-0.667981 | \n", "0.685011 | \n", "-1.942186 | \n", "-0.779483 | \n", "-0.759375 | \n", "0.198692 | \n", "0.043316 | \n", "12 | \n", "
| bcc.su012.post.tcell_TTTGTCAGTCCCTTGT | \n", "-0.059757 | \n", "0.314007 | \n", "1.000176 | \n", "-0.132242 | \n", "0.371538 | \n", "-0.351378 | \n", "-0.189296 | \n", "3.665382 | \n", "-0.018753 | \n", "0.335091 | \n", "... | \n", "-0.520862 | \n", "-0.083217 | \n", "2.131293 | \n", "-0.706136 | \n", "0.002483 | \n", "-0.122560 | \n", "-0.354572 | \n", "1.812793 | \n", "-0.942595 | \n", "3 | \n", "
38836 rows × 87 columns
\n", "| \n", " | patient | \n", "su001 | \n", "su002 | \n", "su003 | \n", "su004 | \n", "su005 | \n", "su006 | \n", "su007 | \n", "su008 | \n", "su009 | \n", "su010 | \n", "su012 | \n", "
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| treatment | \n", "MetaTiME | \n", "\n", " | \n", " | \n", " | \n", " | \n", " | \n", " | \n", " | \n", " | \n", " | \n", " | \n", " |
| post | \n", "B_B | \n", "3447.0 | \n", "0.0 | \n", "8.0 | \n", "19.0 | \n", "55.0 | \n", "18.0 | \n", "2.0 | \n", "127.0 | \n", "2.0 | \n", "0.0 | \n", "0.0 | \n", "
| B_B-Ig-kappa | \n", "12.0 | \n", "3.0 | \n", "0.0 | \n", "3.0 | \n", "8.0 | \n", "537.0 | \n", "0.0 | \n", "27.0 | \n", "0.0 | \n", "0.0 | \n", "2.0 | \n", "|
| B_B-Ig-lambda | \n", "7.0 | \n", "1.0 | \n", "1.0 | \n", "2.0 | \n", "3.0 | \n", "76.0 | \n", "2.0 | \n", "32.0 | \n", "0.0 | \n", "0.0 | \n", "0.0 | \n", "|
| B_B-PAX5 | \n", "273.0 | \n", "0.0 | \n", "0.0 | \n", "0.0 | \n", "0.0 | \n", "0.0 | \n", "0.0 | \n", "0.0 | \n", "0.0 | \n", "0.0 | \n", "0.0 | \n", "|
| B_Plasma | \n", "15.0 | \n", "4.0 | \n", "0.0 | \n", "5.0 | \n", "16.0 | \n", "164.0 | \n", "2.0 | \n", "23.0 | \n", "8.0 | \n", "0.0 | \n", "2.0 | \n", "|
| ... | \n", "... | \n", "... | \n", "... | \n", "... | \n", "... | \n", "... | \n", "... | \n", "... | \n", "... | \n", "... | \n", "... | \n", "... | \n", "
| pre | \n", "T_T-CREM | \n", "72.0 | \n", "4.0 | \n", "7.0 | \n", "33.0 | \n", "64.0 | \n", "83.0 | \n", "126.0 | \n", "12.0 | \n", "324.0 | \n", "7.0 | \n", "100.0 | \n", "
| T_T-Immune-synapse | \n", "47.0 | \n", "0.0 | \n", "6.0 | \n", "22.0 | \n", "28.0 | \n", "35.0 | \n", "82.0 | \n", "4.0 | \n", "146.0 | \n", "6.0 | \n", "130.0 | \n", "|
| T_T-naive | \n", "1.0 | \n", "0.0 | \n", "2.0 | \n", "13.0 | \n", "13.0 | \n", "2.0 | \n", "22.0 | \n", "1.0 | \n", "113.0 | \n", "0.0 | \n", "13.0 | \n", "|
| T_Tfh-CXCL13 | \n", "25.0 | \n", "2.0 | \n", "9.0 | \n", "16.0 | \n", "74.0 | \n", "335.0 | \n", "94.0 | \n", "87.0 | \n", "408.0 | \n", "0.0 | \n", "465.0 | \n", "|
| T_Treg-T-co-signaling | \n", "200.0 | \n", "6.0 | \n", "8.0 | \n", "52.0 | \n", "79.0 | \n", "300.0 | \n", "166.0 | \n", "90.0 | \n", "338.0 | \n", "3.0 | \n", "353.0 | \n", "
76 rows × 11 columns
\n", "| \n", " | -logp | \n", "effect | \n", "effect1 | \n", "meanb | \n", "meana | \n", "scorecol | \n", "cluster1 | \n", "mec | \n", "
|---|---|---|---|---|---|---|---|---|
| M_Monocyte-CD14-proliferation@M_Macrophage-IL1-NFKB | \n", "47.236925 | \n", "-1.885173 | \n", "-1.885173 | \n", "0.486959 | \n", "2.372133 | \n", "MeC_74 | \n", "M_Macrophage-IL1-NFKB | \n", "M_Monocyte-CD14-proliferation | \n", "
| M_Macrophage-IL1-NFKB | \n", "43.831255 | \n", "-2.024648 | \n", "-2.024648 | \n", "4.083235 | \n", "6.107882 | \n", "MeC_42 | \n", "M_Macrophage-IL1-NFKB | \n", "M_Macrophage-IL1-NFKB | \n", "
| T_NK-T-IFNG-CCL4@M_Macrophage-IL1-NFKB | \n", "38.030503 | \n", "-1.774028 | \n", "-1.774028 | \n", "0.264443 | \n", "2.038471 | \n", "MeC_34 | \n", "M_Macrophage-IL1-NFKB | \n", "T_NK-T-IFNG-CCL4 | \n", "